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Search of human proteins with 4759100
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4759100 splicing factor, arginine/serine-rich 11 [Homo
sapiens]
(484 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 949 0.0
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 349 3e-96
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 202 6e-52
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 110 4e-24
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 108 8e-24
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 108 1e-23
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 106 4e-23
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 104 2e-22
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 103 3e-22
gi|52426743 cisplatin resistance-associated overexpressed protei... 102 8e-22
gi|19923485 cisplatin resistance-associated overexpressed protei... 102 8e-22
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 101 1e-21
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 100 2e-21
gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap... 100 2e-21
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 100 3e-21
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 100 3e-21
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 100 3e-21
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 98 1e-20
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 97 3e-20
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 96 6e-20
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 96 7e-20
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 94 3e-19
gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti... 94 3e-19
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 94 3e-19
gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo s... 93 6e-19
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 91 2e-18
gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens] 91 2e-18
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 91 3e-18
gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens] 88 2e-17
gi|38488727 arginine/serine-rich coiled-coil 1 [Homo sapiens] 87 4e-17
>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
Length = 484
Score = 949 bits (2452), Expect = 0.0
Identities = 484/484 (100%), Positives = 484/484 (100%)
Query: 1 MSNTTVVPSTAGPGPSGGPGGGGGGGGGGGGTEVIQVTNVSPSASSEQMRTLFGFLGKID 60
MSNTTVVPSTAGPGPSGGPGGGGGGGGGGGGTEVIQVTNVSPSASSEQMRTLFGFLGKID
Sbjct: 1 MSNTTVVPSTAGPGPSGGPGGGGGGGGGGGGTEVIQVTNVSPSASSEQMRTLFGFLGKID 60
Query: 61 ELRLFPPDDSPLPVSSRVCFVKFHDPDSAVVAQHLTNTVFVDRALIVVPYAEGVIPDEAK 120
ELRLFPPDDSPLPVSSRVCFVKFHDPDSAVVAQHLTNTVFVDRALIVVPYAEGVIPDEAK
Sbjct: 61 ELRLFPPDDSPLPVSSRVCFVKFHDPDSAVVAQHLTNTVFVDRALIVVPYAEGVIPDEAK 120
Query: 121 ALSLLAPANAVAGLLPGGGLLPTPNPLTQIGAVPLAALGAPTLDPALAALGLPGANLNSQ 180
ALSLLAPANAVAGLLPGGGLLPTPNPLTQIGAVPLAALGAPTLDPALAALGLPGANLNSQ
Sbjct: 121 ALSLLAPANAVAGLLPGGGLLPTPNPLTQIGAVPLAALGAPTLDPALAALGLPGANLNSQ 180
Query: 181 SLAADQLLKLMSTVDPKLNHVAAGLVSPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPD 240
SLAADQLLKLMSTVDPKLNHVAAGLVSPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPD
Sbjct: 181 SLAADQLLKLMSTVDPKLNHVAAGLVSPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPD 240
Query: 241 KKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRER 300
KKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRER
Sbjct: 241 KKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRER 300
Query: 301 GRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRS 360
GRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRS
Sbjct: 301 GRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRS 360
Query: 361 PKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQ 420
PKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQ
Sbjct: 361 PKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQ 420
Query: 421 VTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDHHEEDM 480
VTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDHHEEDM
Sbjct: 421 VTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDHHEEDM 480
Query: 481 DMSD 484
DMSD
Sbjct: 481 DMSD 484
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 349 bits (896), Expect = 3e-96
Identities = 252/626 (40%), Positives = 332/626 (53%), Gaps = 186/626 (29%)
Query: 21 GGGGGGGGGGG---TEVIQVTNVSPSASSEQMRTLFGFLGKIDELRLFPPDDSPLPVSSR 77
GGG G G G G T VIQVTN+S + +SEQMRTLF FLG+I+ELRL+PPD++PL SS+
Sbjct: 4 GGGFGLGLGFGLTPTSVIQVTNLSSAVTSEQMRTLFSFLGEIEELRLYPPDNAPLAFSSK 63
Query: 78 VCFVKFHDPDSAVVAQHLTNTVFVDRALIVVPYAEGVIPDEAKALSLLAPANAVAGLLPG 137
VC+VKF DP S VAQHLTNTVF+DRALIVVP AEG IP+E+KALSLLAPA + L+PG
Sbjct: 64 VCYVKFRDPSSVGVAQHLTNTVFIDRALIVVPCAEGKIPEESKALSLLAPAPTMTSLMPG 123
Query: 138 GGLLP--TPNPLTQIGAVPLAALGA---PTLDPALAALG------LPG------------ 174
GLLP TPNPLT +G V L++LGA LDP +A LG L G
Sbjct: 124 AGLLPIPTPNPLTTLG-VSLSSLGAIPAAALDPNIATLGEIPQPPLMGNVDPSKIDEIRR 182
Query: 175 ----ANLNSQSLAADQLLKLMSTVDP---------------------------------- 196
NLNSQ+ ADQLL+ V
Sbjct: 183 TVYVGNLNSQTTTADQLLEFFKQVGEVKFVRMAGDETQPTRFAFVEFADQNSVPRALAFN 242
Query: 197 ---------KLNHVAAGLVSP-SLKSDTSSKEIEEAMKRVREAQSLISAAIEPDK-KEEK 245
K+NH +V P + ++KE+EE MKRVREAQS ISAAIEP+ K +
Sbjct: 243 GVMFGDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNE 302
Query: 246 RRHSRSRSRSRRRRTPSS---SRHRRSRSRSRRRSHSKSRSR----RRSKSPRRR----- 293
R+ RSRS +R + SS SR +RS+S+ R RSH++SRSR RRSKSP ++
Sbjct: 303 RKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSR 362
Query: 294 -------RSHSR-----------------------------------ERGR--------- 302
RSHSR ERG+
Sbjct: 363 ERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKERE 422
Query: 303 --------------RSRSTSKTRDKKKE---DKEK-----------------KRSKTPPK 328
R + K RDK+KE DKEK K+S+TPP+
Sbjct: 423 KDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPR 482
Query: 329 SYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPR-RHKKEKKKDKDKER- 386
SY+ +RRSRS+SRERRRRRSRS +RSP+ ++ KRK SRSPSPR R+KK+KK++K+++
Sbjct: 483 SYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHI 542
Query: 387 -SRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPI 445
R ERERSTS +K S D++ +E+ ++ +K E+ ++ E + K+
Sbjct: 543 SERRERERSTSMRKSSNDRD-GKEKLEKNSTSLK---------EKEHNKEPDSSVSKEVD 592
Query: 446 ETGSPKTKECSVEKGTGDSLRESKVN 471
+ +P+T+E ++ L E ++
Sbjct: 593 DKDAPRTEENKIQHNGNCQLNEENLS 618
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 202 bits (514), Expect = 6e-52
Identities = 173/513 (33%), Positives = 240/513 (46%), Gaps = 183/513 (35%)
Query: 131 VAGLLPGGGLLP--TPNPLTQIGAVPLAALGA---PTLDPALAALG------LPG----- 174
+ L+PG GLLP TPNPLT +G V L++LGA LDP +A LG L G
Sbjct: 1 MTSLMPGAGLLPIPTPNPLTTLG-VSLSSLGAIPAAALDPNIATLGEIPQPPLMGNVDPS 59
Query: 175 -----------ANLNSQSLAADQLLKLMSTVDP--------------------------- 196
NLNSQ+ ADQLL+ V
Sbjct: 60 KIDEIRRTVYVGNLNSQTTTADQLLEFFKQVGEVKFVRMAGDETQPTRFAFVEFADQNSV 119
Query: 197 ----------------KLNHVAAGLVSP-SLKSDTSSKEIEEAMKRVREAQSLISAAIEP 239
K+NH +V P + ++KE+EE MKRVREAQS ISAAIEP
Sbjct: 120 PRALAFNGVMFGDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEP 179
Query: 240 DK-KEEKRRHSRSRSRSRRRRTPSS---SRHRRSRSRSRRRSHSKSRSR----RRSKSPR 291
+ K +R+ RSRS +R + SS SR +RS+S+ R RSH++SRSR RRSKSP
Sbjct: 180 ESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPH 239
Query: 292 RR------------RSHSR-----------------------------------ERGR-- 302
++ RSHSR ERG+
Sbjct: 240 KKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNK 299
Query: 303 ---------------------RSRSTSKTRDKKKE---DKEK-----------------K 321
R + K RDK+KE DKEK K
Sbjct: 300 DRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDK 359
Query: 322 RSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPR-RHKKEKKK 380
+S+TPP+SY+ +RRSRS+SRERRRRRSRS +RSP+ ++ KRK SRSPSPR R+KK+KK+
Sbjct: 360 KSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKR 419
Query: 381 DKDKER--SRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEK 438
+K+++ R ERERSTS +K S D++ +E+ ++ +K E+ ++ E +
Sbjct: 420 EKERDHISERRERERSTSMRKSSNDRD-GKEKLEKNSTSLK---------EKEHNKEPDS 469
Query: 439 KEEKKPIETGSPKTKECSVEKGTGDSLRESKVN 471
K+ + +P+T+E ++ L E ++
Sbjct: 470 SVSKEVDDKDAPRTEENKIQHNGNCQLNEENLS 502
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 110 bits (274), Expect = 4e-24
Identities = 67/195 (34%), Positives = 112/195 (57%), Gaps = 11/195 (5%)
Query: 227 REAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSR--RRSHSKSRSR 284
++ QS +S + K R SRSRSR R+R++ + R RSRSRS+ RR SK +S
Sbjct: 23 KKEQSEVSVSPRASKHHYSR--SRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSS 80
Query: 285 RRSKSPRRR-RSHSRERGRRSRSTSKTRDKKKEDKEKK--RSKTPPKSYSTARRSRSASR 341
++ KS + HS ++GR ++S+ + + + KE+K R ++ +S S RR RS SR
Sbjct: 81 KKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSR 140
Query: 342 ERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKS 401
ER++ RSRS R + RS +RK SRS R ++ K++ + + RSR T + ++
Sbjct: 141 ERKKSRSRSRERKKSRSRSRERKKSRS----RSRERKRRIRSRSRSRSRHRHRTRSRSRT 196
Query: 402 KDKEKDRERKSESDK 416
+ + +DR+++ E +
Sbjct: 197 RSRSRDRKKRIEKPR 211
Score = 66.6 bits (161), Expect = 5e-11
Identities = 47/150 (31%), Positives = 71/150 (47%), Gaps = 9/150 (6%)
Query: 295 SHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGT-- 352
S + G TS RDKKKE E S +P S RSRS SRER+R+ G
Sbjct: 4 SDTERDGLAPEKTSPDRDKKKEQSEV--SVSPRASKHHYSRSRSRSRERKRKSDNEGRKH 61
Query: 353 RSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKS 412
RS + + +R S+ S ++HK E + DKE S D+ + + +D+ K +ERKS
Sbjct: 62 RSRSRSKEGRRHESKDKSSKKHKSE--EHNDKEHSSDKGRERLNSSENGEDRHKRKERKS 119
Query: 413 ESDKDVKQVTRDYDEEEQGYDSEKEKKEEK 442
+ +R E + +E+K+ +
Sbjct: 120 SRG---RSHSRSRSRERRHRSRSRERKKSR 146
Score = 59.3 bits (142), Expect = 8e-09
Identities = 56/201 (27%), Positives = 85/201 (42%), Gaps = 43/201 (21%)
Query: 197 KLNHVAAGLVSPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSR 256
+LN G K SS+ + R RE + + + R +SRSRSR
Sbjct: 101 RLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSR 160
Query: 257 -RRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKK 315
R+++ S SR R+ R RSR RS S+ R R RS RSR+ S++RD+KK
Sbjct: 161 ERKKSRSRSRERKRRIRSRSRSRSRHRHRTRS---------------RSRTRSRSRDRKK 205
Query: 316 EDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKL---SRSPSPR 372
E+ RR SRS +R+P P R ++ R
Sbjct: 206 R------------------------IEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALAR 241
Query: 373 RHKKEKKKDKDKERSRDERER 393
R ++ KK + +E+ E+++
Sbjct: 242 RLERAKKLQEQREKEMVEKQK 262
Score = 42.7 bits (99), Expect = 7e-04
Identities = 32/103 (31%), Positives = 51/103 (49%), Gaps = 4/103 (3%)
Query: 375 KKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDS 434
K +DK KE+S SK S+ + + RERK +SD + ++ R ++G
Sbjct: 15 KTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRK-HRSRSRSKEGRRH 73
Query: 435 EKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDHHE 477
E + K KK ++ KE S +KG + L S+ NG+D H+
Sbjct: 74 ESKDKSSKKH-KSEEHNDKEHSSDKGR-ERLNSSE-NGEDRHK 113
Score = 40.4 bits (93), Expect = 0.004
Identities = 29/137 (21%), Positives = 54/137 (39%), Gaps = 5/137 (3%)
Query: 333 ARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERE 392
A S R++++ +S PR+ K SRS S R +K +K D + + R
Sbjct: 12 APEKTSPDRDKKKEQSEVSV----SPRASKHHYSRSRSRSRERK-RKSDNEGRKHRSRSR 66
Query: 393 RSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKT 452
++ +SKDK + + E + + + + E K +++ G +
Sbjct: 67 SKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHS 126
Query: 453 KECSVEKGTGDSLRESK 469
+ S E+ RE K
Sbjct: 127 RSRSRERRHRSRSRERK 143
Score = 36.2 bits (82), Expect = 0.068
Identities = 27/132 (20%), Positives = 51/132 (38%), Gaps = 7/132 (5%)
Query: 350 SGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRE 409
S R KK +S ++S SP +H + + RSR+ + +S ++ +K + + + +E
Sbjct: 17 SPDRDKKKEQS---EVSVSPRASKHHYSRSRS----RSRERKRKSDNEGRKHRSRSRSKE 69
Query: 410 RKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESK 469
+ KD +E S + +E E G + K + G S S+
Sbjct: 70 GRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSR 129
Query: 470 VNGDDHHEEDMD 481
H +
Sbjct: 130 SRERRHRSRSRE 141
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 108 bits (271), Expect = 8e-24
Identities = 94/252 (37%), Positives = 125/252 (49%), Gaps = 42/252 (16%)
Query: 246 RRHSRSRSRSRRRRTP------SSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRR-----R 294
R HSRSRSRSR R S S H +SRSRSR S S+S+SR RS+S R R
Sbjct: 189 RSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSR 248
Query: 295 SHSRERGR-RSRSTSKTRDKKKEDKEKKRSKTP----PKSYSTAR-----RSRSASRERR 344
S S+E+ R RS S K+R K K+ E+K PKS S +R +SRS S+ERR
Sbjct: 249 SPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERR 308
Query: 345 ----RRRSRSGTRSPKKPRSPKRKLSRSPSPRRHK-----KEKKKDKDKERSRDE---RE 392
+R S S RS +K R SRS R + K K K K ++RSR+E R
Sbjct: 309 VEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRS 368
Query: 393 RSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKT 452
RS SK ++S+ + R+ K+ S K K+ D + S +++E K
Sbjct: 369 RSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAK--------- 419
Query: 453 KECSVEKGTGDS 464
E S +G G+S
Sbjct: 420 SESSQREGRGES 431
Score = 103 bits (258), Expect = 3e-22
Identities = 83/232 (35%), Positives = 118/232 (50%), Gaps = 28/232 (12%)
Query: 240 DKKEEKRR--HSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHS 297
DK +RR +SRSRS SR R SR RSRS S + SHSKSRSR RS S R +S
Sbjct: 175 DKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKS-- 232
Query: 298 RERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYS---TARRSRSASRERRRRRSRSGTRS 354
RSRS S++R KK EK RS + KS S +A +SRS S+++ + ++
Sbjct: 233 -----RSRSQSRSRSKK----EKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNV 283
Query: 355 PK-KPRSPKRKLSRSPS-----PRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDR 408
K K RSP R S+S S RR ++EK+ + RS+++ R + + +SK + R
Sbjct: 284 GKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSR 343
Query: 409 ERKSESDKDVKQVTRDYDEEEQGYDSEKEKKE------EKKPIETGSPKTKE 454
R KD ++ + EE + + K E K+ + GS K K+
Sbjct: 344 SRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKK 395
Score = 97.4 bits (241), Expect = 3e-20
Identities = 72/252 (28%), Positives = 122/252 (48%), Gaps = 17/252 (6%)
Query: 227 REAQSLISAAIEPDKKEEKRRHSRSRSRSRRR-RTPSSSRHRRSRSRS------RRRSHS 279
R+++S ++ K R S SRSRS+ R R+ S SR ++ +SRS R RSHS
Sbjct: 202 RKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHS 261
Query: 280 KSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARR---S 336
+SR +SK + + + + +S S +R K K K RS++ + +R S
Sbjct: 262 AGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHK---SKSKSRSRSQERRVEEEKRGSVS 318
Query: 337 RSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKK---EKKKDKDKERSRDERER 393
R S+E+ R+SRS +RS RS R S+S R+ +K E+ + + + RS+ ER R
Sbjct: 319 RGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSR 378
Query: 394 STSKKKKSKDKEKDRERKSESDK-DVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKT 452
K+ SK +++K ++D+ + +R +E + SE ++E + E
Sbjct: 379 KRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQ 438
Query: 453 KECSVEKGTGDS 464
+ S + S
Sbjct: 439 ETRSRSRSNSKS 450
Score = 92.8 bits (229), Expect = 6e-19
Identities = 67/216 (31%), Positives = 100/216 (46%), Gaps = 24/216 (11%)
Query: 207 SPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKR-RHSRSRSRSRRRRTPSSSR 265
SPS S +RV E + ++ + +EK R SRSRSRS+
Sbjct: 290 SPSRHKSKSKSRSRSQERRVEEEKR---GSVSRGRSQEKSLRQSRSRSRSK--------G 338
Query: 266 HRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRD--------KKKED 317
RSRSRSR +S K + R+RS+ R RS SR + RSR RD KKKED
Sbjct: 339 GSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKED 398
Query: 318 KEKKRSKTPPKSYSTAR---RSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRH 374
++ +S++P +S S R +S S+ RE R +GT + RS S+ P+
Sbjct: 399 TDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSK-PNLPSE 457
Query: 375 KKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRER 410
+ + K K RSR + ++ + S+ + + R
Sbjct: 458 SRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSR 493
Score = 89.4 bits (220), Expect = 7e-18
Identities = 78/286 (27%), Positives = 121/286 (42%), Gaps = 24/286 (8%)
Query: 209 SLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRR---RTPSSSR 265
S S + S+ + R R S + KKE+ R S+ +SRSR ++ S S+
Sbjct: 211 SKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSK 270
Query: 266 HR--------------RSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTR 311
+ +SRS SR +S SKSRSR + + + S RGR + +
Sbjct: 271 DQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQS 330
Query: 312 DKKKEDKEKKRSKTPPKSYST-ARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPS 370
+ K RS++ +S S R+ R SRE R RSRS ++S RS KR R
Sbjct: 331 RSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKS---ERSRKRGSKRDSK 387
Query: 371 PRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDK-DVKQVTRDYDEEE 429
KK+KK+D D+ +SR + +++ +K + RE + ES+ Q TR
Sbjct: 388 AGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETR--SRSR 445
Query: 430 QGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDH 475
S+ E + + KT+ S + S S+ H
Sbjct: 446 SNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSH 491
Score = 76.6 bits (187), Expect = 5e-14
Identities = 64/195 (32%), Positives = 99/195 (50%), Gaps = 25/195 (12%)
Query: 291 RRRRSHSRERGRRSRSTSKTRDKKKED-KEKKRSKTPPKSYSTAR-RSRSASRERRRRRS 348
RRRRS+SR SRS S++R + + K + RS + S+S +R RSRS SR R + RS
Sbjct: 180 RRRRSYSR-----SRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRS 234
Query: 349 RSGTRS---PKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDE----------RERST 395
RS +RS +K RSP ++ SRS R H K + K K+++ ++ + RS
Sbjct: 235 RSQSRSRSKKEKSRSPSKEKSRS---RSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSP 291
Query: 396 SK-KKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKE 454
S+ K KSK + + +ER+ E +K V+R +E+ S + + ++K
Sbjct: 292 SRHKSKSKSRSRSQERRVEEEKR-GSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKS 350
Query: 455 CSVEKGTGDSLRESK 469
KG S ES+
Sbjct: 351 KDKRKGRKRSREESR 365
Score = 63.5 bits (153), Expect = 4e-10
Identities = 52/166 (31%), Positives = 79/166 (47%), Gaps = 20/166 (12%)
Query: 316 EDKEKKRSKTPPKSYSTAR-RSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRH 374
EDK R + +SYS +R SRS SR R R+SRS + S K S R SRS S R
Sbjct: 174 EDKPGSRRR---RSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGS-RSR 229
Query: 375 KKEKKKDKDKERSRDERERSTSKKK---------KSKDKEKDRERKSESDKDVKQVTRDY 425
K + + + + RS+ E+ RS SK+K KS+ K KD+ + + D +
Sbjct: 230 SKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSR 289
Query: 426 DEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGD--SLRESK 469
S+ + +++ +E + K SV +G SLR+S+
Sbjct: 290 SPSRHKSKSKSRSRSQERRVE----EEKRGSVSRGRSQEKSLRQSR 331
Score = 58.2 bits (139), Expect = 2e-08
Identities = 45/146 (30%), Positives = 62/146 (42%), Gaps = 2/146 (1%)
Query: 328 KSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERS 387
K S RRS S SR R RSRS + RS K S S S R + + + K RS
Sbjct: 176 KPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKS-RSRSRSGSRSRSKSRS 234
Query: 388 RDE-RERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIE 446
R + R RS +K +S KEK R R + K + +E+ Q D+ + K
Sbjct: 235 RSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRH 294
Query: 447 TGSPKTKECSVEKGTGDSLRESKVNG 472
K++ S E+ + R S G
Sbjct: 295 KSKSKSRSRSQERRVEEEKRGSVSRG 320
Score = 38.1 bits (87), Expect = 0.018
Identities = 21/53 (39%), Positives = 31/53 (58%)
Query: 229 AQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKS 281
++S ++ +P+ E R S+S S++R R S RS SRSR RSHS+S
Sbjct: 442 SRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494
Score = 35.8 bits (81), Expect = 0.089
Identities = 27/77 (35%), Positives = 36/77 (46%), Gaps = 1/77 (1%)
Query: 211 KSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSR 270
KS++S +E + Q S + + K + S SRSRS+ S RSR
Sbjct: 419 KSESSQREGRGESENAGTNQETRSRS-RSNSKSKPNLPSESRSRSKSASKTRSRSKSRSR 477
Query: 271 SRSRRRSHSKSRSRRRS 287
S SR S S+SRS RS
Sbjct: 478 SASRSPSRSRSRSHSRS 494
Score = 30.0 bits (66), Expect = 4.9
Identities = 31/125 (24%), Positives = 53/125 (42%), Gaps = 10/125 (8%)
Query: 363 RKLSRSPSPRR---HKKEKKKDKDKERSRDERE-RSTS-KKKKSKDKEKDRER---KSES 414
R + P RR + + + + + RSR R+ RS S K S K + R R +S S
Sbjct: 171 RLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRS 230
Query: 415 DKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGS-PKTKECSVEK-GTGDSLRESKVNG 472
+ +R ++E+ KEK + S K+K+ + EK D++ + K
Sbjct: 231 KSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRS 290
Query: 473 DDHHE 477
H+
Sbjct: 291 PSRHK 295
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 108 bits (269), Expect = 1e-23
Identities = 93/288 (32%), Positives = 138/288 (47%), Gaps = 30/288 (10%)
Query: 212 SDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRS 271
S +SSKE + +S S + P+K+ R HSRSRS ++ R S ++R
Sbjct: 368 SRSSSKERDHRGSSSPRKESGRSQSGSPNKQ---RDHSRSRSPNKARDRSRSRSPYKARD 424
Query: 272 RSRRRSHSKSRSRRRSKSPRRRRSHSRERG-------RRSRSTSKTRDKKKE---DKEKK 321
RSR RS +K+R RS+SP + R SR R RSRS +K RD+ + KE+
Sbjct: 425 RSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERD 484
Query: 322 RSKT-PPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKK- 379
S+ P RRSRS S+ER+ R+SRS + K R +R SRSPS R +++ +
Sbjct: 485 HSQLGSPSKERDHRRSRSPSKERQCRQSRSSS----KERDHRR--SRSPSKERQRRQSRS 538
Query: 380 --KDKDKERSRDERERSTSKKKKSKDKEKDRER-KSESDKDVKQVTRDYDEEEQGYDSEK 436
K++D+ +SR E ++ +S KE+DR R +S S + ++ +R EE S
Sbjct: 539 PNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRS 598
Query: 437 EKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDHHEEDMDMSD 484
K ++G + + S EK S SK SD
Sbjct: 599 PNK------QSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESD 640
Score = 99.8 bits (247), Expect = 5e-21
Identities = 80/289 (27%), Positives = 130/289 (44%), Gaps = 50/289 (17%)
Query: 245 KRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRR------SKSPRRRRSHS- 297
KR HSR+RSR+R+ RH +SRS S+ +S ++SR+ RR S++P + RSHS
Sbjct: 308 KRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSH 367
Query: 298 -----------------RERGR-------------RSRSTSKTRDKKK-----EDKEKKR 322
+E GR RSRS +K RD+ + + +++ R
Sbjct: 368 SRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSR 427
Query: 323 SKTPPKSYSTAR-RSRSASRERRRRRSRSGTRSPKKPRSPK----RKLSRSPSPRRHKKE 377
S++P K+ +R RS +R+R R RS + R + RSP R SRSPS R +
Sbjct: 428 SRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQ 487
Query: 378 ---KKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDS 434
K++D RSR + ++ +S KE+D R K+ ++ +E+
Sbjct: 488 LGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQ 547
Query: 435 EKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDHHEEDMDMS 483
+ EE++ ++ SP + + RE + + E D S
Sbjct: 548 SRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRS 596
Score = 95.1 bits (235), Expect = 1e-19
Identities = 80/313 (25%), Positives = 128/313 (40%), Gaps = 46/313 (14%)
Query: 205 LVSPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSS 264
++ PS + S E+ +K +A + + + HS+SRS R R
Sbjct: 248 MIIPSREKSYSPTEMSSRVKSYNQAST----------RSRPQSHSQSRSPRRSRSGSQKR 297
Query: 265 RHRRSRSRSRRRSHSKSRSRRR------------------------SKSPRRRRSH---- 296
H R RS S +R+HS++RSR R S++PRR RSH
Sbjct: 298 THSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSR 357
Query: 297 --SRERGR-RSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTR 353
S+ER SRS+SK RD + +K S +R S SR + R RS +R
Sbjct: 358 NPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSR 417
Query: 354 SPKKPRSPKRKLSRSPSPRR---HKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRER 410
SP K R R SRSP+ R + K +D+ RSR + + +S +K +DR R
Sbjct: 418 SPYKARD--RSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSR 475
Query: 411 KSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESKV 470
K+ +E+ + + +E++ ++ S + + R+ +
Sbjct: 476 SRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQ 535
Query: 471 NGDDHHEEDMDMS 483
+ + E D S
Sbjct: 536 SRSPNKERDRSQS 548
Score = 91.7 bits (226), Expect = 1e-18
Identities = 72/241 (29%), Positives = 115/241 (47%), Gaps = 32/241 (13%)
Query: 242 KEEKRRHSRSRSRSR---RRRTPSSSRHR-RSRSRSRRRSHS------KSRSRRRSKSPR 291
K R SRS +++R R R+P+ +R R RSRS S+ R HS K R RRS+SP
Sbjct: 445 KARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPS 504
Query: 292 RRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSG 351
+ R + R+SRS+SK RD +RS++P K R R SR + R RS
Sbjct: 505 KER-----QCRQSRSSSKERD-------HRRSRSPSK-----ERQRRQSRSPNKERDRSQ 547
Query: 352 TRSPKKPRSPKRKLSRSPS---PRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDR 408
+RSP + R + + SRSPS RR + K++++ +SR E + +S +K+
Sbjct: 548 SRSPSEER--EHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGY 605
Query: 409 ERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRES 468
R S K+ +E + + +E P ++ P++ + SL ++
Sbjct: 606 SRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQN 665
Query: 469 K 469
+
Sbjct: 666 R 666
Score = 74.7 bits (182), Expect = 2e-13
Identities = 75/238 (31%), Positives = 110/238 (46%), Gaps = 33/238 (13%)
Query: 207 SPSLKSDTS-----SKEIEEAMKRV----REAQSLISAAIEPD-------KKEEKRRHSR 250
SPS + D S SKE + R R+ + S++ E D KE +RR SR
Sbjct: 478 SPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSR 537
Query: 251 SRSRSRRR---RTPSSSR-HRRSRS------RSRRRSHSKSRSRRRSKSPRRRRSHSRER 300
S ++ R R R+PS R HR+SRS R R RS SK R RR+S+S R HSR R
Sbjct: 538 SPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSR 597
Query: 301 GRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRS 360
+S ++K RS+TP K +SR++S+E +S + RSP RS
Sbjct: 598 SPNKQSGYSRPRASSKEKAHSRSRTPSKE-GNHSQSRTSSKESDPSQS-TVPRSPDWKRS 655
Query: 361 PKR--KLSRSPSPRR---HKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSE 413
P R LS++ +P + H + S+D+ + + K + E+ S+
Sbjct: 656 PTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATTSKATLPGERSSSSSSK 713
Score = 58.2 bits (139), Expect = 2e-08
Identities = 65/279 (23%), Positives = 104/279 (37%), Gaps = 30/279 (10%)
Query: 161 PTLDPALAALGLPGANLNSQSLAADQLLKLMSTVDPKLNHVAAGLVSPSLKSDTSSKEIE 220
PT DP P A+L S A S V K ++SPS T S +
Sbjct: 22 PTADPK------PPASLKSTKSATPN----RSLVPTKPATSRNSVMSPSSSKSTKSTSTK 71
Query: 221 EAMKRVREAQSLI-SAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHS 279
A ++S + S A P + R S++ S R H R R+ RR S S
Sbjct: 72 RAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTPGRRGSRS 131
Query: 280 KSRSRRRSKSPRRRRSH--------------SRERGRRSRSTSKTRDKKKEDKEKKRSKT 325
RS R+ +P R R+H S+++G R +S + R +E + +
Sbjct: 132 SKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNL 191
Query: 326 PPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDK--- 382
KSY S R + S + P ++ S +PSP +K K +
Sbjct: 192 SKKSYRPPGGS-GIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMII 250
Query: 383 -DKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQ 420
+E+S E S+ K ++ + R + + ++
Sbjct: 251 PSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRR 289
Score = 47.8 bits (112), Expect = 2e-05
Identities = 94/397 (23%), Positives = 140/397 (35%), Gaps = 95/397 (23%)
Query: 134 LLPGGGLLPTPNPLTQIGAVPLAALGAPTLDPALAALGLPGANLNS-QSLAADQLLKLMS 192
L P G +PT +P L + + T + +L P + NS S ++ + K S
Sbjct: 14 LAPSGSSMPTADPKPPAS---LKSTKSATPNRSLVPTK-PATSRNSVMSPSSSKSTKSTS 69
Query: 193 TVDPKLNHVAAGLVSPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSR 252
T N PS +S SK RV A+ D + +RR + SR
Sbjct: 70 TKRAPSNR-------PSSRSRVRSKA--RTPSRVSTDTRTSKASKASDVRCHQRRGTHSR 120
Query: 253 SRSRRRRTPSSSRHRRSRSRS--RRRSH-------------------SKSRSRRRSKSPR 291
R+ RR SS+ SR+ + R R+H S+ +S R ++
Sbjct: 121 GRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSN 180
Query: 292 RRRSHSRER---------------GRRSR-----STSKTR------DKKKEDKEKKRSKT 325
R RS S+ R GR S ST+K + K+K D S
Sbjct: 181 RERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSR 240
Query: 326 PPKSY---------------------------STARRSRSASRERRRRRSRSGTRSPKKP 358
KSY ST R +S S+ R RRSRSG S K+
Sbjct: 241 KVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSG--SQKRT 298
Query: 359 RSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSES---- 414
S R S + R + +K + R + RS SK K R +S +
Sbjct: 299 HSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRN 358
Query: 415 -DKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSP 450
K+ +E+ + ++E ++GSP
Sbjct: 359 PSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSP 395
Score = 33.9 bits (76), Expect = 0.34
Identities = 30/127 (23%), Positives = 47/127 (37%), Gaps = 11/127 (8%)
Query: 289 SPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRS 348
SP+R S S K + +S TP +S + + S
Sbjct: 3 SPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPA----------TS 52
Query: 349 RSGTRSPKKPRSPK-RKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKD 407
R+ SP +S K R+PS R + + + K + SR + TSK K+ D
Sbjct: 53 RNSVMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCH 112
Query: 408 RERKSES 414
+ R + S
Sbjct: 113 QRRGTHS 119
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 106 bits (265), Expect = 4e-23
Identities = 66/271 (24%), Positives = 133/271 (49%), Gaps = 22/271 (8%)
Query: 211 KSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHS-RSRSRSRRRRTPSSSRHRRS 269
K++ E +R RE ++ + D++ +++R + R R + R S R
Sbjct: 200 KTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERD 259
Query: 270 RSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKE-DKEKKRSKTPPK 328
+ R R R + R RR+ + R+ + R R R T + R++++E ++E++R++
Sbjct: 260 KERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNR---- 315
Query: 329 SYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRH-------KKEKKKD 381
+R R RER R R R R +K R KRK R+ +++ +++
Sbjct: 316 -----KRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERE 370
Query: 382 KDKERSRDE---RERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEK-E 437
+++ER RD RER ++ + +D++K+RER++E D+D ++ T E E+ +SE+
Sbjct: 371 RERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGR 430
Query: 438 KKEEKKPIETGSPKTKECSVEKGTGDSLRES 468
++ ++ + G + +E ++ G + S
Sbjct: 431 ERGREREKQKGRERDRERQTDRQAGRQRKRS 461
Score = 105 bits (261), Expect = 1e-22
Identities = 69/275 (25%), Positives = 121/275 (44%), Gaps = 21/275 (7%)
Query: 217 KEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRR 276
+E +R RE Q E + K E R R R R R R T + + +R R R R
Sbjct: 181 REKNRQERRERERQR------EKENKTEDRHSERGRERERERETETETERKRQTDRERDR 234
Query: 277 SHSKSRSRRRSKSPRRRRSHSRERGR---RSRSTSKTRDKKKEDKEKKRSKTPPKSYSTA 333
+ R R K R R+ RE R R R + RD+ + KE++R + T
Sbjct: 235 Q--RKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTE 292
Query: 334 R---------RSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKK-DKD 383
R R R RER R R R R ++ R +R+ R R +K K++ + D
Sbjct: 293 RDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMD 352
Query: 384 KERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKK 443
+ER+R + ++ +++E++R+R+S +++ ++ RD D +++ ++ ++ ++
Sbjct: 353 RERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQR 412
Query: 444 PIETGSPKTKECSVEKGTGDSLRESKVNGDDHHEE 478
E + K+ E+G K G + E
Sbjct: 413 ETEKQREREKDRESERGRERGREREKQKGRERDRE 447
Score = 103 bits (258), Expect = 3e-22
Identities = 62/227 (27%), Positives = 113/227 (49%), Gaps = 7/227 (3%)
Query: 238 EPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHS 297
E +++ EKR+ R R R RR +R R R R+R K R R+ + R+R
Sbjct: 61 ERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKE 120
Query: 298 RERGR-RSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPK 356
R R + R R T + ++ ++ + + + + + R R RER+R+ R+ R +
Sbjct: 121 RNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERN--RQKE 178
Query: 357 KPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRD-ERERST---SKKKKSKDKEKDRERKS 412
+ R R+ R +R K+ K +D+ ER R+ ERER T +++K+ D+E+DR+RK+
Sbjct: 179 REREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKT 238
Query: 413 ESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEK 459
E +++ + E E D E+E++ ++ K +E ++
Sbjct: 239 EREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDR 285
Score = 99.4 bits (246), Expect = 7e-21
Identities = 64/266 (24%), Positives = 128/266 (48%), Gaps = 16/266 (6%)
Query: 215 SSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRH-RRSRSRS 273
+ KE E R R+ Q+ + E ++ E+ R+ R R R R + + RH R R R
Sbjct: 155 AEKERERQTDRERQRQTERNRQKERER-EKNRQERRERERQREKENKTEDRHSERGRERE 213
Query: 274 RRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTA 333
R R R+R R R ER R ++ + +++ +++K+R + +
Sbjct: 214 RERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRD 273
Query: 334 RRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERER 393
RR + R+ R+R R R + R +R+ R R ++ +K+++++ER R+ +
Sbjct: 274 RRQKERERQTDRKRQRRTERDRETERKRERQRERE---RERERNRKRERERERERERERQ 330
Query: 394 STSKKKKSKDKEKDRERKSESDKD---------VKQVTRDYD-EEEQGYDSEKEKKEEKK 443
+++ + K++E+ R+R++E D++ +Q R+ + E E+ S +E++E ++
Sbjct: 331 RETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERER 390
Query: 444 PIETGSPKTKECSVEKGTGDSLRESK 469
+ K +E EK D RE++
Sbjct: 391 DRDRDRQKERERQTEKDR-DGQRETE 415
Score = 95.5 bits (236), Expect = 1e-19
Identities = 52/212 (24%), Positives = 105/212 (49%), Gaps = 14/212 (6%)
Query: 241 KKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRER 300
+KE +R R R R R+T R R + R R R+R R++ RE+
Sbjct: 124 QKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREK 183
Query: 301 GR---RSRSTSKTRDKKKEDKEKKRSKTPPKSYSTA-----RRSRSASRERRRRRSRSGT 352
R R R + ++ K ED+ +R + + T +R R+R+R+ R
Sbjct: 184 NRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTERERE 243
Query: 353 RSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKK---SKDKEKDRE 409
+ ++ R+ +R+ R + ++E+ +D+D++R + ERER T +K++ +D+E +R+
Sbjct: 244 KQAERERASERETERD---KERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERK 300
Query: 410 RKSESDKDVKQVTRDYDEEEQGYDSEKEKKEE 441
R+ + +++ ++ E E+ + E+E++ E
Sbjct: 301 RERQRERERERERNRKRERERERERERERQRE 332
Score = 95.5 bits (236), Expect = 1e-19
Identities = 68/282 (24%), Positives = 133/282 (47%), Gaps = 18/282 (6%)
Query: 217 KEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRR 276
+E E +R R+ Q+ E + EK R R R R+R+T + + R R ++R+
Sbjct: 129 RETEREGERGRDRQTDGQRERERQRDAEKERE-RQTDRERQRQTERNRQKEREREKNRQE 187
Query: 277 SHSKSRSRRR-SKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRS-KTPPKSYSTAR 334
+ R R + +K+ R RER R + ++T K++ D+E+ R KT + A
Sbjct: 188 RRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAE 247
Query: 335 RSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRD----- 389
R R++ RE R + R R + R ++K + R+ ++ ++D++ ER R+
Sbjct: 248 RERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRER 307
Query: 390 ERERSTSKKK---KSKDKEKDRERKSESDKD-------VKQVTRDYDEEEQGYDSEKEKK 439
ERER ++K+ + +++E++R+R++E D++ +Q D + Q + +
Sbjct: 308 ERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQA 367
Query: 440 EEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDHHEEDMD 481
E ++ E + E+ D R+ + + E+D D
Sbjct: 368 ERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRD 409
Score = 94.7 bits (234), Expect = 2e-19
Identities = 59/221 (26%), Positives = 108/221 (48%), Gaps = 18/221 (8%)
Query: 239 PDKKEEKRRHSRSRSRSR-----RRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRR 293
P +E RR ++ R R R RR R R + R RRR K R+
Sbjct: 31 PGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRK 90
Query: 294 RSHSRERGR-----RSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRS 348
R RER R R R T + RD+++E + ++ + ++ R R + +R R
Sbjct: 91 RDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERE 150
Query: 349 RSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDK---- 404
R ++ R R+ R + R +KE++++K+++ R ERER K+ K++D+
Sbjct: 151 RQRDAEKERERQTDRERQRQ-TERNRQKEREREKNRQERR-ERERQREKENKTEDRHSER 208
Query: 405 --EKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKK 443
E++RER++E++ + K+ T + ++ + E+EK+ E++
Sbjct: 209 GRERERERETETETERKRQTDRERDRQRKTEREREKQAERE 249
Score = 90.9 bits (224), Expect = 2e-18
Identities = 57/239 (23%), Positives = 114/239 (47%), Gaps = 13/239 (5%)
Query: 217 KEIEEAMKRVREAQSLISAAIEPDKKEEKRR-HSRSRSRSRRRRTPSSSRHRRSRSRSRR 275
+E + KR R + E +++ ++ R R + R+R++ + R R R+
Sbjct: 83 REKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQ 142
Query: 276 RSHSKSRSRRRSKSPRRRRSHSRERGR---RSRSTSKTRDKKKE---DKEKKRSKTPPKS 329
+ R R+R R R RER R R+R + R+K ++ ++E++R K
Sbjct: 143 TDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTE 202
Query: 330 YSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSR-----SPSPRRHKKEKKKDKDK 384
+ R R RER R + R +RK R + R ++E ++DK++
Sbjct: 203 DRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKER 262
Query: 385 ERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKK 443
ER RD R+R +++K ++++ DR+R+ +++D + + + E+ + E+ +K E++
Sbjct: 263 ERERD-RDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERE 320
Score = 87.0 bits (214), Expect = 3e-17
Identities = 58/241 (24%), Positives = 107/241 (44%), Gaps = 12/241 (4%)
Query: 250 RSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSK 309
R S+ RR H+ + R R+ K R RRR K R + + RR + +
Sbjct: 30 RPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHR 89
Query: 310 TRDKKKE---DKEKKRSKTPPKSYSTAR-RSRSASRERRRRRSRSGTRSPKKPRSPKRKL 365
RD+ +E D+EK+R + + R + R+ +ER R R G R + +R+
Sbjct: 90 KRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRER 149
Query: 366 SRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDY 425
R R +KE+++ D+ER R ++++ K++++ RER+ + +K+ K R
Sbjct: 150 ERQ---RDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHS 206
Query: 426 D-----EEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDHHEEDM 480
+ E E+ ++E E+K + KT+ ++ + E + D E +
Sbjct: 207 ERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERER 266
Query: 481 D 481
D
Sbjct: 267 D 267
Score = 83.6 bits (205), Expect = 4e-16
Identities = 54/197 (27%), Positives = 104/197 (52%), Gaps = 14/197 (7%)
Query: 255 SRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKK 314
SRRR S RR ++ + + R R R K RR RE+ + R T + R+++
Sbjct: 27 SRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERR----REKRQTERETDRKRERR 82
Query: 315 KE-DKEKKRSKTPPKSYSTAR-RSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRS---P 369
+E D+ +KR + + + R R RER R+R + R ++ R +R+ R
Sbjct: 83 REKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQ 142
Query: 370 SPRRHKKEKKKDKDKERSRD---ERERSTSK-KKKSKDKEKDRERKSESDKDVKQVTRDY 425
+ + ++E+++D +KER R ER+R T + ++K +++EK+R+ + E ++ ++ +
Sbjct: 143 TDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTE 202
Query: 426 D-EEEQGYDSEKEKKEE 441
D E+G + E+E++ E
Sbjct: 203 DRHSERGRERERERETE 219
Score = 70.1 bits (170), Expect = 4e-12
Identities = 56/197 (28%), Positives = 94/197 (47%), Gaps = 27/197 (13%)
Query: 292 RRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSG 351
RRR S+E RR +D +D+E+ R K + + R R+R RRR
Sbjct: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRR---- 83
Query: 352 TRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRD-ERERSTSK-KKKSKDKEKDRE 409
+K R KR RH+ E+++D++KER R +RER + K++++ KE++RE
Sbjct: 84 ----EKDRHRKRD--------RHR-ERQRDREKERERQTDRERDRQREKERNRQKERERE 130
Query: 410 RKSESDKDVKQVTRDYDEEEQGYDSEKEK-----KEEKKPIETGSPKTKECS---VEKGT 461
+ E ++ + T E E+ D+EKE+ +E ++ E K +E E+
Sbjct: 131 TEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRE 190
Query: 462 GDSLRESKVNGDDHHEE 478
+ RE + +D H E
Sbjct: 191 RERQREKENKTEDRHSE 207
Score = 57.4 bits (137), Expect = 3e-08
Identities = 46/168 (27%), Positives = 74/168 (44%), Gaps = 13/168 (7%)
Query: 217 KEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRR 276
+E E +R RE Q E ++ E KR+ R R R+T R + R R R R
Sbjct: 317 RERERERERERERQRETERDREKER-ERKRKRQTEMDRERNRQTGREGRRQAERERERER 375
Query: 277 SHSKSRSRRRSKSPRRR-RSHSRERGRRS-------RSTSKTRDKKKE---DKEKKRSKT 325
+ +R R + R R R +ER R++ R T K R+++K+ ++ ++R +
Sbjct: 376 ERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGRE 435
Query: 326 PPKSYSTAR-RSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPR 372
K R R R R+ R+R RS PR+ + + +S R
Sbjct: 436 REKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNR 483
Score = 47.4 bits (111), Expect = 3e-05
Identities = 41/170 (24%), Positives = 62/170 (36%), Gaps = 16/170 (9%)
Query: 218 EIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRS 277
E E +R R+ QS ++ E+R R R R + R + R ++R
Sbjct: 368 ERERERERERDRQSA--------REREERERDRDRDRQKERERQTEKDRDGQRETEKQRE 419
Query: 278 HSKSRSRRRSKSPRRRRSHSRERGR-RSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRS 336
K R R + R R +++GR R R R ++ K PP R +
Sbjct: 420 REKDRESERGR--ERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPP-----PRTA 472
Query: 337 RSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKER 386
RS + R G R P PK +R P R K + + + R
Sbjct: 473 RSGVVQSDPNRPTRGIRWKSSPEDPKAASTRFPWGRPAKASRGRVAGRRR 522
Score = 43.5 bits (101), Expect = 4e-04
Identities = 36/135 (26%), Positives = 61/135 (45%), Gaps = 23/135 (17%)
Query: 362 KRKLSRSPSPRR------HKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESD 415
+R+ SPRR HK D+++ R + ERER K++ ++ ++ RER+ E D
Sbjct: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQK-ERERRREKRQTERETDRKRERRREKD 86
Query: 416 KDVKQVTRDYDEEEQGYDSEKEKKEEK---------KPIETGSPKTKECSVEKGTGDSLR 466
+ K RD E Q ++EK+ E+ + E K +E E+ G+ R
Sbjct: 87 RHRK---RDRHRERQ---RDREKERERQTDRERDRQREKERNRQKERERETER-EGERGR 139
Query: 467 ESKVNGDDHHEEDMD 481
+ + +G E D
Sbjct: 140 DRQTDGQRERERQRD 154
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 104 bits (260), Expect = 2e-22
Identities = 74/224 (33%), Positives = 123/224 (54%), Gaps = 18/224 (8%)
Query: 264 SRHRRSRSRSRRRSHSKSRSR----RRSKSPRRRRSHSRERGRRSRSTSKTRDKKKE-DK 318
SRH R RS SR RS S+SRSR +RSK RRS SR+R RR R S++RDK++ +
Sbjct: 5 SRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRR-RERSRSRDKRRSRSR 63
Query: 319 EKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKR-KLSRSPSPRRHKKE 377
++KR RRSRS R+R R R RS +R ++ RS R + SRS SP +K +
Sbjct: 64 DRKR----------LRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPG-NKSK 112
Query: 378 KKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKE 437
K +++ + + + + S+ +KKK KD ++D + K + D ++ + + ++ + +E
Sbjct: 113 KTENRSRSKEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWRE 172
Query: 438 KKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDHHEEDMD 481
++ +K G K + +++G SL + + DD E + +
Sbjct: 173 EQRKKAMENIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKE 216
Score = 103 bits (256), Expect = 5e-22
Identities = 73/212 (34%), Positives = 117/212 (55%), Gaps = 19/212 (8%)
Query: 245 KRRHSRSRSRSRRR-RTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRR 303
KR SR RS SR R R+PS R +R R R RS + R R RS+S +RRS SR+R R
Sbjct: 10 KRSASRGRSGSRSRSRSPSDKRSKRGDDR-RSRSRDRDRRRERSRSRDKRRSRSRDRKRL 68
Query: 304 SRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPK-KPRSPK 362
RS S+ RD+ +E ++RS++ + RRSRS SR RR R S G +S K + RS
Sbjct: 69 RRSRSRERDRSRE---RRRSRSRDR-----RRSRSRSRGRRSRSSSPGNKSKKTENRSRS 120
Query: 363 RKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDR------ERKSESDK 416
++ + + KK+ K DK+ E+ +D +K ++ K K+R E++ ++ +
Sbjct: 121 KEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKAME 180
Query: 417 DVKQVTRDYDEEEQG--YDSEKEKKEEKKPIE 446
++ ++ ++ +E +QG + E + +E P E
Sbjct: 181 NIGELKKEIEEMKQGKKWSLEDDDDDEDDPAE 212
Score = 99.4 bits (246), Expect = 7e-21
Identities = 70/221 (31%), Positives = 106/221 (47%), Gaps = 12/221 (5%)
Query: 234 SAAIEPDKKEEKR---RHSRSRSRSRRRRTPSSSRHRRSRSR-------SRRRSHSKSRS 283
S + P K KR R SRSR R RRR S RRSRSR SR R +SR
Sbjct: 22 SRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRE 81
Query: 284 RRRSKSPRRRRSHSRERGRRSRSTSK-TRDKKKEDKEKKRSKTPPKSYSTARRSRSASRE 342
RRRS+S RRRS SR RGRRSRS+S + KK E++ + + KT S ++ +E
Sbjct: 82 RRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKDDKE 141
Query: 343 RRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSK 402
+ + K +++ R R +++K + E ++ E KK +
Sbjct: 142 DEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKAMENIGELKKEIEEMKQGKKWSLE 201
Query: 403 DKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKK 443
D + D + +E++K+ ++ + + Y E+ K+E KK
Sbjct: 202 DDDDDEDDPAEAEKEGNEMEGEELDPLDAY-MEEVKEEVKK 241
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 103 bits (258), Expect = 3e-22
Identities = 51/187 (27%), Positives = 97/187 (51%), Gaps = 3/187 (1%)
Query: 238 EPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHS 297
E +K++ +R R R R ++ + R R +R+ K R RR K R+R+
Sbjct: 42 EREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEK 101
Query: 298 RERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKK 357
++R R+ R + R KKKE KE++R + +R + R+ R+R G R K
Sbjct: 102 KKRERKQRGR-RERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERK- 159
Query: 358 PRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKD 417
R ++K R R++KE+KK+++++ R+ ++ +++K K+++KDR+ ++D
Sbjct: 160 -RKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQ 218
Query: 418 VKQVTRD 424
V + R+
Sbjct: 219 VFRPLRE 225
Score = 101 bits (251), Expect = 2e-21
Identities = 54/205 (26%), Positives = 103/205 (50%), Gaps = 6/205 (2%)
Query: 267 RRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTP 326
+R R + R + R R R K +R R ++ R+ R K R++K++++EK+R +
Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
Query: 327 PKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKER 386
K RR R +++R R+ R R +K + +++ R RR +K KK+ K K R
Sbjct: 91 EKE----RRKRKKEKKKRERKQRG--RRERKKKKERKERERENKQRRERKRKKRRKKKRR 144
Query: 387 SRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIE 446
+RE+ K+++ + K K ER+ + +++ K+ ++ + +E+ ++ KKE +K E
Sbjct: 145 KERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKE 204
Query: 447 TGSPKTKECSVEKGTGDSLRESKVN 471
+ + + LRES N
Sbjct: 205 RKKDRKTDRQTDSQVFRPLRESAFN 229
Score = 100 bits (250), Expect = 2e-21
Identities = 58/184 (31%), Positives = 97/184 (52%), Gaps = 15/184 (8%)
Query: 241 KKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRER 300
KKE + R R R R + R+ R ++ + + ++R K R R+R K ++R RE+
Sbjct: 37 KKERREREKRKREREKERKR---ERGKKEKKKRKKRERGKERERKR-KEREKQRKERREK 92
Query: 301 GRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRS 360
RR R K KK+E K++ R + K R+ R ++RR R R R K+ +
Sbjct: 93 ERRKRKKEK---KKRERKQRGRRERKKKK---ERKERERENKQRRERKRKKRRKKKRRKE 146
Query: 361 PKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKK-----SKDKEKDRERKSESD 415
KR+ R R+ KK KK++++K+R R+ +ER +++K K+++K+R +K E
Sbjct: 147 RKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERK 206
Query: 416 KDVK 419
KD K
Sbjct: 207 KDRK 210
Score = 85.9 bits (211), Expect = 8e-17
Identities = 56/184 (30%), Positives = 86/184 (46%), Gaps = 29/184 (15%)
Query: 211 KSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRR---RRTPSSSRHR 267
K K+ E +R R+ + E +KE ++R + R R+ RR + R
Sbjct: 61 KEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKER 120
Query: 268 RSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPP 327
+ R R ++ + R +RR K R+ R +ERG+R R K + +KKE++EKKR +
Sbjct: 121 KERERENKQRRERKRKKRRKKKRRKERKREKERGKRER---KRKKRKKEEREKKRERN-- 175
Query: 328 KSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERS 387
R+ R RER+ RR R KK R + RR KKE+KKD+ +R
Sbjct: 176 ------RKERKKERERKERRER------KKERKKE---------RRKKKERKKDRKTDRQ 214
Query: 388 RDER 391
D +
Sbjct: 215 TDSQ 218
Score = 71.2 bits (173), Expect = 2e-12
Identities = 57/204 (27%), Positives = 94/204 (46%), Gaps = 21/204 (10%)
Query: 269 SRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPK 328
SR+ + + + S P +R R++ RR R +K+K ++EK+R + K
Sbjct: 7 SRAAVKLNTELQMVSCSHISKPCTQRESERKKERRER------EKRKREREKERKRERGK 60
Query: 329 SYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKER-S 387
R+ R +ER R+R K R +RK R R+ KKEK K +ER
Sbjct: 61 KEKKKRKKRERGKERERKR---------KEREKQRKERREKERRKRKKEK---KKRERKQ 108
Query: 388 RDERERSTSKKKKSKDKE--KDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPI 445
R RER K++K +++E + RERK + + K+ E+E+G K KK +K+
Sbjct: 109 RGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEER 168
Query: 446 ETGSPKTKECSVEKGTGDSLRESK 469
E + ++ ++ RE K
Sbjct: 169 EKKRERNRKERKKERERKERRERK 192
Score = 47.4 bits (111), Expect = 3e-05
Identities = 28/106 (26%), Positives = 51/106 (48%), Gaps = 2/106 (1%)
Query: 374 HKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYD 433
H + ++ ER ++ RER K+K+ ++KE+ RER + K K+ R + E + +
Sbjct: 24 HISKPCTQRESERKKERRERE--KRKREREKERKRERGKKEKKKRKKRERGKERERKRKE 81
Query: 434 SEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDHHEED 479
EK++KE ++ K K+ K G R+ K + E+
Sbjct: 82 REKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKEREREN 127
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 102 bits (254), Expect = 8e-22
Identities = 75/231 (32%), Positives = 110/231 (47%), Gaps = 10/231 (4%)
Query: 213 DTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSR 272
D S+ + M + + I A +E + KE+ R+ + R R + R R + R
Sbjct: 203 DAQSRVDDHLMGKQHMGYAKIKATVE-ELKEKLRKRTEEPDRDERLKKEKQEREEREKER 261
Query: 273 SRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYST 332
R R + + RR + + R+ RER +RSRS S+ + D+ RS+ +S S
Sbjct: 262 EREREERERKRRREEEEREKERARDRERRKRSRSRSR-HSSRTSDRRCSRSRDHKRSRS- 319
Query: 333 ARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHK---KEKKKDKDKERSRD 389
R R SR R RRRSRS RS +K RS R RS S R + K +D++++R
Sbjct: 320 --RERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSK 377
Query: 390 ERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKE 440
E+E+ S KKS K RE++SE D + + D E G SE K E
Sbjct: 378 EKEKRGSDDKKSSVKSGSREKQSE-DTNTESKESDTKNEVNG-TSEDIKSE 426
Score = 94.7 bits (234), Expect = 2e-19
Identities = 71/221 (32%), Positives = 105/221 (47%), Gaps = 30/221 (13%)
Query: 210 LKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRS 269
L+ T + +E +K+ E Q E +++ E+R R R R + + R RR
Sbjct: 234 LRKRTEEPDRDERLKK--EKQEREEREKEREREREERERKRRREEEEREKERARDRERRK 291
Query: 270 RSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKS 329
RSRSR R S++ RR S+S +RS SRER RRSRS +
Sbjct: 292 RSRSRSRHSSRTSDRRCSRSRDHKRSRSRER-RRSRSRDR-------------------- 330
Query: 330 YSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRD 389
RRSRS R R+ RSRS R K R K RS S R + K K+K+K S D
Sbjct: 331 ----RRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDD 386
Query: 390 ERE--RSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEE 428
++ +S S++K+S+D + ++S++ +V + D E
Sbjct: 387 KKSSVKSGSREKQSEDTNTE-SKESDTKNEVNGTSEDIKSE 426
Score = 87.4 bits (215), Expect = 3e-17
Identities = 64/246 (26%), Positives = 108/246 (43%), Gaps = 23/246 (9%)
Query: 210 LKSDTSSKEIEEAMKRVREAQSLISA-AIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRR 268
L+S TS+ E A ++ E + A I D + H + + ++ +
Sbjct: 172 LRSTTSTIESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELK 231
Query: 269 SRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPK 328
+ R R + ++ K R R RER R R + R++++ +KE+ R +
Sbjct: 232 EKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRE--- 288
Query: 329 SYSTARRSRSASRERRRRRSR----SGTRSPKKPRSPKRKLSRSPSPRR-------HKKE 377
RR RS SR R R+ S +R K+ RS +R+ SRS RR +K
Sbjct: 289 -----RRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKH 343
Query: 378 KKKDKDKERSRDERERSTSKKKKSKDKEKDR---ERKSESDKDVKQVTRDYDEEEQGYDS 434
+ + +D+ RS+ +S + KS+D+E+DR E++ D K + E+Q D+
Sbjct: 344 RSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDT 403
Query: 435 EKEKKE 440
E KE
Sbjct: 404 NTESKE 409
Score = 72.0 bits (175), Expect = 1e-12
Identities = 51/205 (24%), Positives = 98/205 (47%), Gaps = 37/205 (18%)
Query: 288 KSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRR-- 345
K R+R+ +R R + + R+++++++E++R + R+RRR
Sbjct: 231 KEKLRKRTEEPDRDERLKKEKQEREEREKEREREREER--------------ERKRRREE 276
Query: 346 ------------RRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERER 393
RR RS +RS R+ R+ SRS R HK+ + +++ + RSRD R
Sbjct: 277 EEREKERARDRERRKRSRSRSRHSSRTSDRRCSRS---RDHKRSRSRERRRSRSRDRRRS 333
Query: 394 STSKKKKSKDKEKDRER---KSESDKDVKQVTRDYDEEEQGYDSEKEKK---EEKKPIET 447
+ + + K + + R+R KS K K ++ D E+ EKEK+ ++K +++
Sbjct: 334 RSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKS 393
Query: 448 GSPKTKECSVEKGTGDSLRESKVNG 472
GS + + + +S +++VNG
Sbjct: 394 GSREKQSEDTNTESKESDTKNEVNG 418
>gi|19923485 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 102 bits (254), Expect = 8e-22
Identities = 75/231 (32%), Positives = 110/231 (47%), Gaps = 10/231 (4%)
Query: 213 DTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSR 272
D S+ + M + + I A +E + KE+ R+ + R R + R R + R
Sbjct: 203 DAQSRVDDHLMGKQHMGYAKIKATVE-ELKEKLRKRTEEPDRDERLKKEKQEREEREKER 261
Query: 273 SRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYST 332
R R + + RR + + R+ RER +RSRS S+ + D+ RS+ +S S
Sbjct: 262 EREREERERKRRREEEEREKERARDRERRKRSRSRSR-HSSRTSDRRCSRSRDHKRSRS- 319
Query: 333 ARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHK---KEKKKDKDKERSRD 389
R R SR R RRRSRS RS +K RS R RS S R + K +D++++R
Sbjct: 320 --RERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSK 377
Query: 390 ERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKE 440
E+E+ S KKS K RE++SE D + + D E G SE K E
Sbjct: 378 EKEKRGSDDKKSSVKSGSREKQSE-DTNTESKESDTKNEVNG-TSEDIKSE 426
Score = 94.7 bits (234), Expect = 2e-19
Identities = 71/221 (32%), Positives = 105/221 (47%), Gaps = 30/221 (13%)
Query: 210 LKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRS 269
L+ T + +E +K+ E Q E +++ E+R R R R + + R RR
Sbjct: 234 LRKRTEEPDRDERLKK--EKQEREEREKEREREREERERKRRREEEEREKERARDRERRK 291
Query: 270 RSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKS 329
RSRSR R S++ RR S+S +RS SRER RRSRS +
Sbjct: 292 RSRSRSRHSSRTSDRRCSRSRDHKRSRSRER-RRSRSRDR-------------------- 330
Query: 330 YSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRD 389
RRSRS R R+ RSRS R K R K RS S R + K K+K+K S D
Sbjct: 331 ----RRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDD 386
Query: 390 ERE--RSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEE 428
++ +S S++K+S+D + ++S++ +V + D E
Sbjct: 387 KKSSVKSGSREKQSEDTNTE-SKESDTKNEVNGTSEDIKSE 426
Score = 87.4 bits (215), Expect = 3e-17
Identities = 64/246 (26%), Positives = 108/246 (43%), Gaps = 23/246 (9%)
Query: 210 LKSDTSSKEIEEAMKRVREAQSLISA-AIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRR 268
L+S TS+ E A ++ E + A I D + H + + ++ +
Sbjct: 172 LRSTTSTIESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELK 231
Query: 269 SRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPK 328
+ R R + ++ K R R RER R R + R++++ +KE+ R +
Sbjct: 232 EKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRE--- 288
Query: 329 SYSTARRSRSASRERRRRRSR----SGTRSPKKPRSPKRKLSRSPSPRR-------HKKE 377
RR RS SR R R+ S +R K+ RS +R+ SRS RR +K
Sbjct: 289 -----RRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKH 343
Query: 378 KKKDKDKERSRDERERSTSKKKKSKDKEKDR---ERKSESDKDVKQVTRDYDEEEQGYDS 434
+ + +D+ RS+ +S + KS+D+E+DR E++ D K + E+Q D+
Sbjct: 344 RSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDT 403
Query: 435 EKEKKE 440
E KE
Sbjct: 404 NTESKE 409
Score = 72.0 bits (175), Expect = 1e-12
Identities = 51/205 (24%), Positives = 98/205 (47%), Gaps = 37/205 (18%)
Query: 288 KSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRR-- 345
K R+R+ +R R + + R+++++++E++R + R+RRR
Sbjct: 231 KEKLRKRTEEPDRDERLKKEKQEREEREKEREREREER--------------ERKRRREE 276
Query: 346 ------------RRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERER 393
RR RS +RS R+ R+ SRS R HK+ + +++ + RSRD R
Sbjct: 277 EEREKERARDRERRKRSRSRSRHSSRTSDRRCSRS---RDHKRSRSRERRRSRSRDRRRS 333
Query: 394 STSKKKKSKDKEKDRER---KSESDKDVKQVTRDYDEEEQGYDSEKEKK---EEKKPIET 447
+ + + K + + R+R KS K K ++ D E+ EKEK+ ++K +++
Sbjct: 334 RSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKS 393
Query: 448 GSPKTKECSVEKGTGDSLRESKVNG 472
GS + + + +S +++VNG
Sbjct: 394 GSREKQSEDTNTESKESDTKNEVNG 418
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 101 bits (252), Expect = 1e-21
Identities = 78/299 (26%), Positives = 141/299 (47%), Gaps = 23/299 (7%)
Query: 206 VSPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSR 265
V+P + +KE A++ + + LIS I + K+ + + R+ R
Sbjct: 250 VAPLIPYPLITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKER 309
Query: 266 HRRSRSRSR---RRSHSKSRSRRRSKSPRRRRSHSRERGR-RSRSTSKTRDKKKE-DKEK 320
R R R R RR + R R R + + R RER R R R+ + RD+ +E D+++
Sbjct: 310 RERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDR 369
Query: 321 KRSKTPPKSYSTAR-RSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKK 379
R ++ ++ +R R +S RER R R R R ++ R +R+ R R ++E++
Sbjct: 370 DRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERE---RERERERE 426
Query: 380 KDKDKERSRDERERSTSKKKKSKDKEKD---RERKSESDKDVKQVTRDYD-----EEEQG 431
KDK ++R DE + +K + K +EK+ +ER + ++ TR+Y+ EEE+
Sbjct: 427 KDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERR 486
Query: 432 YDSEKEKKEEKKPIE-----TGSPK-TKECSVEKGTGDSLRESKVNGDDHHEEDMDMSD 484
+ KE K K+ +E PK + +++K D +E + + D E ++ +
Sbjct: 487 REMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEE 545
Score = 94.0 bits (232), Expect = 3e-19
Identities = 83/331 (25%), Positives = 137/331 (41%), Gaps = 72/331 (21%)
Query: 213 DTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSR 272
DT K EE K+ +E Q + E +++ E+ R R R R R R R R R
Sbjct: 286 DTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERER 345
Query: 273 SRRRSHSKSRSRRRSKSPRRRRSHSRERGR-----RSRSTSKTRDKKKE-DKEKKRSKTP 326
R R +++ R R + R R RER RSRS K+RD+++E ++E++R +
Sbjct: 346 ERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERER 405
Query: 327 PKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSP-------KRKLSRSPSP-------- 371
+ R R RER R R R + K+ R +RKL R
Sbjct: 406 ERE-----REREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQER 460
Query: 372 ------RRHKKEKKKDKDKERSRDERE--------------------------RSTSKKK 399
R KK ++ +K+ ER + R R ++ +K
Sbjct: 461 LKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQK 520
Query: 400 KSKDKEK-------DRERKSESDKDVKQVT-----RDYDEEEQGYDSEKEKKEEKKPIET 447
+ +D+EK DR+R+ E ++++Q D D E Q + E E++ ++P
Sbjct: 521 RLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERR--RQPQIK 578
Query: 448 GSPKTKECSVEKGTGDSLRESKVNGDDHHEE 478
P+++E EK + RE + ++ E+
Sbjct: 579 QEPESEEEEEEKQEKEEKREEPMEEEEEPEQ 609
Score = 36.6 bits (83), Expect = 0.052
Identities = 54/242 (22%), Positives = 86/242 (35%), Gaps = 32/242 (13%)
Query: 224 KRVREAQSLISAAIEPDKKEEKRRHSRSRSR--SRRRRTPSSSRHRRSRSRSRRRSHSKS 281
KR+R+ + + A E D+K EK R R + P + R + RRR
Sbjct: 520 KRLRDREKEMEAD-ERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRR----- 573
Query: 282 RSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSAS- 340
+ + K E+ + + ++++E ++K K + S+A SAS
Sbjct: 574 --QPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPCLKPTLRPISSAPSVSSASG 631
Query: 341 ------------------RERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDK 382
E + + PK S K S SP K KK
Sbjct: 632 NATPNTPGDESPCGIIIPHENSPDQQQPEEHRPKIGLSLKLGASNSPGQPNSVKRKKLPV 691
Query: 383 DKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEK 442
D ++ E E S +K K D E DK+ + T + +E+ + S EK
Sbjct: 692 DSVFNKFEDEDSDDVPRKRKLVPLD---YGEDDKNATKGTVNTEEKRKHIKSLIEKIPTA 748
Query: 443 KP 444
KP
Sbjct: 749 KP 750
Score = 35.8 bits (81), Expect = 0.089
Identities = 46/198 (23%), Positives = 84/198 (42%), Gaps = 27/198 (13%)
Query: 301 GRRSRSTSKTRDKKKEDKEKKRSKTPPKS--------YST---ARRSRSASRERRRRRSR 349
G T D++ D+E KR K YS+ A S S R++++ +
Sbjct: 181 GNARPETVTNDDEEALDEETKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEK 240
Query: 350 SGT---RSPKKPRSPKRKLSRSPSPRRHKKEKKKD---KDKERSRDERERSTSKKKKSKD 403
R P P P +++ +E K+D ++ + RD ++ +K K
Sbjct: 241 KEDIFRRFPVAPLIPYPLITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGK--- 297
Query: 404 KEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGD 463
KEK+R+ E +K+ ++ R+ + E + + E+E++ E+ E K +E E+ D
Sbjct: 298 KEKERQ---EIEKERRERERERERERERRERERERERER---EREKEKERERERERDR-D 350
Query: 464 SLRESKVNGDDHHEEDMD 481
R + + D E D D
Sbjct: 351 RDRTKERDRDRDRERDRD 368
>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 100 bits (250), Expect = 2e-21
Identities = 76/224 (33%), Positives = 116/224 (51%), Gaps = 28/224 (12%)
Query: 234 SAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSK-------SRSRRR 286
++ +EP KKE K + + RSRS + SSS + R+ S S S S SR+ R
Sbjct: 490 TSVLEP-KKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSR 548
Query: 287 SKSPRRRRSHSRERG-----RRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASR 341
S SP+R++ HSR R RRSRS S +R + K + + R K + RRS S
Sbjct: 549 SSSPKRKKRHSRSRSPTIKARRSRSRSYSR-RIKIESNRARVKIRDR-----RRSNRNSI 602
Query: 342 ERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKS 401
ER RRR+RS +R ++ RS RS R ++ + + +D+ + D+R + K
Sbjct: 603 ERERRRNRSPSRERRRSRS------RSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKH 656
Query: 402 KDKEKDRERKSESDKDVKQVTRDYDEE---EQGYDSEKEKKEEK 442
K + K++ERK E + + + + D+E EQ EK+K+EEK
Sbjct: 657 KGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEK 700
Score = 97.8 bits (242), Expect = 2e-20
Identities = 88/281 (31%), Positives = 140/281 (49%), Gaps = 48/281 (17%)
Query: 219 IEEAMKRVREAQSLISAAIEPDKKEEKRRHSR-----SRSRSRRRRTPSSSRHRRSRSRS 273
+ E + E S++ E K++EK+ SR S S S RT S+S S S S
Sbjct: 479 VNEKKRTPNETTSVLEPKKE-HKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYS 537
Query: 274 RRRSHSKSRSRRRSKSPRRRRSHSRER-----GRRSRSTS--------------KTRDKK 314
S SR+ RS SP+R++ HSR R RRSRS S K RD++
Sbjct: 538 --SSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRR 595
Query: 315 KE-----DKEKKRSKTPPKSYSTARRSRSASRERR-RRRSRSGTRSPKKPRSPKRKLSRS 368
+ ++E++R+++P + RRSRS SR+RR R SRS +R +K + L S
Sbjct: 596 RSNRNSIERERRRNRSPSRE---RRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNL--S 650
Query: 369 PSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEE 428
+ +HK E K+ + K+ ER RS K +K KDKE++RE+ +K + +E+
Sbjct: 651 GNSHKHKGEAKEQERKK----ERSRSIDKDRKKKDKEREREQDKRKEKQKR------EEK 700
Query: 429 EQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESK 469
+ + S+ ++ + K+ E ++ SV+ DS ++SK
Sbjct: 701 DFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSK 741
Score = 88.6 bits (218), Expect = 1e-17
Identities = 78/283 (27%), Positives = 127/283 (44%), Gaps = 26/283 (9%)
Query: 207 SPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEE---------KRRHSRSRSRSRR 257
S S S TSS + + S + P +K+ K R SRSRS SRR
Sbjct: 520 SNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRR 579
Query: 258 RRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSP--RRRRSHSRERGRRSRSTSKTRDKKK 315
+ S+ + R R R +S R RRR++SP RRRS SR R RR+ S++R + +
Sbjct: 580 IKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDR 639
Query: 316 EDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHK 375
+ +R S+ + + ++E+ R++ RS RS K R K K +R +
Sbjct: 640 RKIDDQRGNLSGNSH----KHKGEAKEQERKKERS--RSIDKDRKKKDKEREREQDKRKE 693
Query: 376 KEKKKDKD-KERSRDER-------ERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDE 427
K+K+++KD K S+D+R ER+ S+ K + + +S K + ++ +
Sbjct: 694 KQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSG 753
Query: 428 EEQGYDSEKEKKEEKKPIETGSPK-TKECSVEKGTGDSLRESK 469
+ S E K + PK ++ SVEK + S+
Sbjct: 754 SDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASR 796
Score = 80.9 bits (198), Expect = 2e-15
Identities = 67/243 (27%), Positives = 115/243 (47%), Gaps = 10/243 (4%)
Query: 207 SPSLKSDTS-SKEIEEAMK-RVREAQSLISAAIEPDKKEEKRRHSRSRSRSR-RRRTPSS 263
SP++K+ S S+ +K A+ I ++ +R R+RS SR RRR+ S
Sbjct: 563 SPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSR 622
Query: 264 SRHRR----SRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGR---RSRSTSKTRDKKKE 316
SR RR SRSRSR R + S + + + ++E+ R RSRS K R KK +
Sbjct: 623 SRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDK 682
Query: 317 DKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKK 376
++E+++ K K + + +S++ R +R R R+ + S K+ R S + KK
Sbjct: 683 EREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKK 742
Query: 377 EKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEK 436
KD K D RS+S+ S ++K ++ K + V++ R + + + S+
Sbjct: 743 STTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKS 802
Query: 437 EKK 439
+
Sbjct: 803 RSR 805
Score = 35.8 bits (81), Expect = 0.089
Identities = 39/145 (26%), Positives = 63/145 (43%), Gaps = 11/145 (7%)
Query: 300 RGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSA-SRERRRRRSRSGTRSPKKP 358
+ RR R +S RD+++ + PP+ + RR+ A RE + R + +K
Sbjct: 196 QNRRERPSS-FRDRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKE 254
Query: 359 RSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDV 418
R +++ S KKEKK +D E + R + K D+E++ E+
Sbjct: 255 RMEQQRSQLS------KKEKKATEDAEGG--DGPRLPQRSKFDSDEEEEDTENVEAASSG 306
Query: 419 KQVTRDYDEEEQGYDSEKEKKEEKK 443
K VTR Q S+ E EE+K
Sbjct: 307 K-VTRSPSPVPQEEHSDPEMTEEEK 330
Score = 33.9 bits (76), Expect = 0.34
Identities = 38/178 (21%), Positives = 66/178 (37%), Gaps = 18/178 (10%)
Query: 316 EDKEKKRSKTPPKSYSTARRSRS----------ASRERRRRRSRSGTRSPKKPRSPKRKL 365
+D +K +K P K + + S S + RS G+ S R
Sbjct: 359 KDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHR 418
Query: 366 SRSPSPRRHKKEKKK----DKDKERSRDERERSTSKKKKSKDKEKDR----ERKSESDKD 417
R +KEK++ DK E + + ER T + + KE++ E +
Sbjct: 419 IRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDV 478
Query: 418 VKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDH 475
V + R +E + +KE KE++K + S + S + S S V+ +
Sbjct: 479 VNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSY 536
Score = 33.1 bits (74), Expect = 0.58
Identities = 21/79 (26%), Positives = 41/79 (51%), Gaps = 5/79 (6%)
Query: 201 VAAGLVSPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKR----RHSRSRSRSR 256
++ ++ + D+ +++ K S S++ P +EK+ +HSRSRS +
Sbjct: 727 ISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEK 786
Query: 257 RRRT-PSSSRHRRSRSRSR 274
+R+ +SR +S+SRSR
Sbjct: 787 SQRSGKKASRKHKSKSRSR 805
Score = 32.3 bits (72), Expect = 0.99
Identities = 31/173 (17%), Positives = 57/173 (32%), Gaps = 8/173 (4%)
Query: 271 SRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSY 330
S R S + R R +E R + K+ ++EK++++ K
Sbjct: 396 SEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEM 455
Query: 331 STARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDE 390
+ S R G +K R+P S + HK+++K+ + + S
Sbjct: 456 NEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSS 515
Query: 391 RERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKK 443
S++ + S S S + +R S K KK +
Sbjct: 516 GSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRS--------SSPKRKKRHSR 560
>gi|154146193 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 100 bits (250), Expect = 2e-21
Identities = 76/224 (33%), Positives = 116/224 (51%), Gaps = 28/224 (12%)
Query: 234 SAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSK-------SRSRRR 286
++ +EP KKE K + + RSRS + SSS + R+ S S S S SR+ R
Sbjct: 490 TSVLEP-KKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSR 548
Query: 287 SKSPRRRRSHSRERG-----RRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASR 341
S SP+R++ HSR R RRSRS S +R + K + + R K + RRS S
Sbjct: 549 SSSPKRKKRHSRSRSPTIKARRSRSRSYSR-RIKIESNRARVKIRDR-----RRSNRNSI 602
Query: 342 ERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKS 401
ER RRR+RS +R ++ RS RS R ++ + + +D+ + D+R + K
Sbjct: 603 ERERRRNRSPSRERRRSRS------RSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKH 656
Query: 402 KDKEKDRERKSESDKDVKQVTRDYDEE---EQGYDSEKEKKEEK 442
K + K++ERK E + + + + D+E EQ EK+K+EEK
Sbjct: 657 KGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEK 700
Score = 97.8 bits (242), Expect = 2e-20
Identities = 88/281 (31%), Positives = 140/281 (49%), Gaps = 48/281 (17%)
Query: 219 IEEAMKRVREAQSLISAAIEPDKKEEKRRHSR-----SRSRSRRRRTPSSSRHRRSRSRS 273
+ E + E S++ E K++EK+ SR S S S RT S+S S S S
Sbjct: 479 VNEKKRTPNETTSVLEPKKE-HKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYS 537
Query: 274 RRRSHSKSRSRRRSKSPRRRRSHSRER-----GRRSRSTS--------------KTRDKK 314
S SR+ RS SP+R++ HSR R RRSRS S K RD++
Sbjct: 538 --SSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRR 595
Query: 315 KE-----DKEKKRSKTPPKSYSTARRSRSASRERR-RRRSRSGTRSPKKPRSPKRKLSRS 368
+ ++E++R+++P + RRSRS SR+RR R SRS +R +K + L S
Sbjct: 596 RSNRNSIERERRRNRSPSRE---RRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNL--S 650
Query: 369 PSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEE 428
+ +HK E K+ + K+ ER RS K +K KDKE++RE+ +K + +E+
Sbjct: 651 GNSHKHKGEAKEQERKK----ERSRSIDKDRKKKDKEREREQDKRKEKQKR------EEK 700
Query: 429 EQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESK 469
+ + S+ ++ + K+ E ++ SV+ DS ++SK
Sbjct: 701 DFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSK 741
Score = 88.6 bits (218), Expect = 1e-17
Identities = 78/283 (27%), Positives = 127/283 (44%), Gaps = 26/283 (9%)
Query: 207 SPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEE---------KRRHSRSRSRSRR 257
S S S TSS + + S + P +K+ K R SRSRS SRR
Sbjct: 520 SNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRR 579
Query: 258 RRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSP--RRRRSHSRERGRRSRSTSKTRDKKK 315
+ S+ + R R R +S R RRR++SP RRRS SR R RR+ S++R + +
Sbjct: 580 IKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDR 639
Query: 316 EDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHK 375
+ +R S+ + + ++E+ R++ RS RS K R K K +R +
Sbjct: 640 RKIDDQRGNLSGNSH----KHKGEAKEQERKKERS--RSIDKDRKKKDKEREREQDKRKE 693
Query: 376 KEKKKDKD-KERSRDER-------ERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDE 427
K+K+++KD K S+D+R ER+ S+ K + + +S K + ++ +
Sbjct: 694 KQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSG 753
Query: 428 EEQGYDSEKEKKEEKKPIETGSPK-TKECSVEKGTGDSLRESK 469
+ S E K + PK ++ SVEK + S+
Sbjct: 754 SDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASR 796
Score = 80.9 bits (198), Expect = 2e-15
Identities = 67/243 (27%), Positives = 115/243 (47%), Gaps = 10/243 (4%)
Query: 207 SPSLKSDTS-SKEIEEAMK-RVREAQSLISAAIEPDKKEEKRRHSRSRSRSR-RRRTPSS 263
SP++K+ S S+ +K A+ I ++ +R R+RS SR RRR+ S
Sbjct: 563 SPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSR 622
Query: 264 SRHRR----SRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGR---RSRSTSKTRDKKKE 316
SR RR SRSRSR R + S + + + ++E+ R RSRS K R KK +
Sbjct: 623 SRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDK 682
Query: 317 DKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKK 376
++E+++ K K + + +S++ R +R R R+ + S K+ R S + KK
Sbjct: 683 EREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKK 742
Query: 377 EKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEK 436
KD K D RS+S+ S ++K ++ K + V++ R + + + S+
Sbjct: 743 STTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKS 802
Query: 437 EKK 439
+
Sbjct: 803 RSR 805
Score = 35.8 bits (81), Expect = 0.089
Identities = 39/145 (26%), Positives = 63/145 (43%), Gaps = 11/145 (7%)
Query: 300 RGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSA-SRERRRRRSRSGTRSPKKP 358
+ RR R +S RD+++ + PP+ + RR+ A RE + R + +K
Sbjct: 196 QNRRERPSS-FRDRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKE 254
Query: 359 RSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDV 418
R +++ S KKEKK +D E + R + K D+E++ E+
Sbjct: 255 RMEQQRSQLS------KKEKKATEDAEGG--DGPRLPQRSKFDSDEEEEDTENVEAASSG 306
Query: 419 KQVTRDYDEEEQGYDSEKEKKEEKK 443
K VTR Q S+ E EE+K
Sbjct: 307 K-VTRSPSPVPQEEHSDPEMTEEEK 330
Score = 33.9 bits (76), Expect = 0.34
Identities = 38/178 (21%), Positives = 66/178 (37%), Gaps = 18/178 (10%)
Query: 316 EDKEKKRSKTPPKSYSTARRSRS----------ASRERRRRRSRSGTRSPKKPRSPKRKL 365
+D +K +K P K + + S S + RS G+ S R
Sbjct: 359 KDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHR 418
Query: 366 SRSPSPRRHKKEKKK----DKDKERSRDERERSTSKKKKSKDKEKDR----ERKSESDKD 417
R +KEK++ DK E + + ER T + + KE++ E +
Sbjct: 419 IRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDV 478
Query: 418 VKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDH 475
V + R +E + +KE KE++K + S + S + S S V+ +
Sbjct: 479 VNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSY 536
Score = 33.1 bits (74), Expect = 0.58
Identities = 21/79 (26%), Positives = 41/79 (51%), Gaps = 5/79 (6%)
Query: 201 VAAGLVSPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKR----RHSRSRSRSR 256
++ ++ + D+ +++ K S S++ P +EK+ +HSRSRS +
Sbjct: 727 ISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEK 786
Query: 257 RRRT-PSSSRHRRSRSRSR 274
+R+ +SR +S+SRSR
Sbjct: 787 SQRSGKKASRKHKSKSRSR 805
Score = 32.3 bits (72), Expect = 0.99
Identities = 31/173 (17%), Positives = 57/173 (32%), Gaps = 8/173 (4%)
Query: 271 SRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSY 330
S R S + R R +E R + K+ ++EK++++ K
Sbjct: 396 SEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEM 455
Query: 331 STARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDE 390
+ S R G +K R+P S + HK+++K+ + + S
Sbjct: 456 NEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSS 515
Query: 391 RERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKK 443
S++ + S S S + +R S K KK +
Sbjct: 516 GSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRS--------SSPKRKKRHSR 560
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 100 bits (249), Expect = 3e-21
Identities = 82/254 (32%), Positives = 124/254 (48%), Gaps = 28/254 (11%)
Query: 216 SKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRS-RRRRTPSSSRHR-RSRSRS 273
S + ++R +E Q L A E +E++RR SRS R RRR+ S RHR RSRSR
Sbjct: 288 SSSFDRELEREKERQRLEREAKE---REKERRRSRSIDRGLERRRSRSRERHRSRSRSRD 344
Query: 274 R---RRSHSKSRSRRRSKSPRRRRSHSRERG-------RRSRSTSKTR--------DKKK 315
R RR + R + + RR R + +ERG RSR SK + K K
Sbjct: 345 RKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHK 404
Query: 316 EDKEKKRSKTPPK-SYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRH 374
EDK+ +R + + S + SRS SRE R+ RSRS +R+ K RS R +S +
Sbjct: 405 EDKDDRRHRDDKRDSKKEKKHSRSRSRE-RKHRSRSRSRNAGK-RSRSRSKEKSSKHKNE 462
Query: 375 KKEK--KKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGY 432
KEK K+ + + R + + K++ S KEK R+R ++ K+ D ++ +
Sbjct: 463 SKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKH 522
Query: 433 DSEKEKKEEKKPIE 446
D + + E++ E
Sbjct: 523 DRRRSQSIEQESQE 536
Score = 98.2 bits (243), Expect = 1e-20
Identities = 81/250 (32%), Positives = 114/250 (45%), Gaps = 26/250 (10%)
Query: 245 KRRHSRSRSRSRRRRTPSSS------RHRRSRSRSRRRSHSKSRSRRRSKSP----RRRR 294
+R RSRSRS R SS + R R R + + + RRRS+S RRR
Sbjct: 270 RRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRR 329
Query: 295 SHSRERGR-RSRSTSKTRDKKKED----KEKKRSKTPPKSYSTAR-----RSRSASRERR 344
S SRER R RSRS + D++ D KE +R + + Y R + R SRER
Sbjct: 330 SRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERS 389
Query: 345 RRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKK--KKSK 402
+ + G KK + K R KKEKK + + R R R RS S+ K+S+
Sbjct: 390 KEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSR 449
Query: 403 DKEKDRERKSESDKDVKQVTRDYDEEEQGYDS-EKEKKEEKKPIETGSPK---TKECSVE 458
+ K++ K +++ K R + DS EK KK E P + S K +KE S +
Sbjct: 450 SRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHK 509
Query: 459 KGTGDSLRES 468
+ DS +S
Sbjct: 510 RDHSDSKDQS 519
Score = 97.1 bits (240), Expect = 3e-20
Identities = 72/256 (28%), Positives = 121/256 (47%), Gaps = 12/256 (4%)
Query: 233 ISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRH-RRSRSRSRRRSHSKSRSRRRSKSPR 291
I ++ + ++ + R + + RH R RSRS RRS S RS RRS+S
Sbjct: 221 IPVPVQKNIDQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRS-- 278
Query: 292 RRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSG 351
RSH RE S+S R+ ++E + ++ + + RRSRS R RRRSRS
Sbjct: 279 --RSHHREG---HGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSR 333
Query: 352 TRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERK 411
R + RS RK R R +KE ++ + ++R D+ + +K++ + +E+ +E++
Sbjct: 334 ERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQR 393
Query: 412 SESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLR---ES 468
S + + K+ D D+ D +++ K+EKK + S + K S + R S
Sbjct: 394 SRGEVEEKKHKEDKDDRRH-RDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRS 452
Query: 469 KVNGDDHHEEDMDMSD 484
K H E + S+
Sbjct: 453 KEKSSKHKNESKEKSN 468
Score = 95.5 bits (236), Expect = 1e-19
Identities = 75/246 (30%), Positives = 117/246 (47%), Gaps = 27/246 (10%)
Query: 243 EEKRRH-SRSRSRSRRRRTPSSSRHRRSRSRSRRR----SHSKSRSRRRSKSPRRRRSHS 297
EE RH R RSRS RR RRSRSRS R S S R R K +R +
Sbjct: 249 EEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREA 308
Query: 298 RERG---RRSRSTSKTRDKKKE-DKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTR 353
+ER RRSRS + ++++ +E+ RS++ + RR R RE+ R R R
Sbjct: 309 KEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDR 368
Query: 354 SPKKPRSPKRKLSRSPSPRRHKKEK----------KKDKDKERSRDERERSTSKKKKSKD 403
K R +R+ R S R K+++ K+DKD R RD++ S +KK S+
Sbjct: 369 DYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRS 428
Query: 404 KEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGD 463
+ ++R+ +S S +R+ + + EK K + + E + +++ S +G D
Sbjct: 429 RSRERKHRSRSR------SRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGS--QGRTD 480
Query: 464 SLRESK 469
S+ +SK
Sbjct: 481 SVEKSK 486
Score = 91.7 bits (226), Expect = 1e-18
Identities = 66/246 (26%), Positives = 113/246 (45%), Gaps = 22/246 (8%)
Query: 217 KEIEEAMKRVREAQSLISAAIEPDKKEEKRRH-SRSRSRSR--------RRRTPSSSRHR 267
+E +E K R ++S I +E + + RH SRSRSR R R R + R R
Sbjct: 306 REAKEREKERRRSRS-IDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGR 364
Query: 268 R-----SRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKK- 321
R + R R + RSR RSK R R ++ + + + RD K++ K++K
Sbjct: 365 RRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKK 424
Query: 322 --RSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKK 379
RS++ + + + RSR+A + R R ++ + + K SRS S R +K
Sbjct: 425 HSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEK 484
Query: 380 KDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKK 439
K + E+ R S+ K+ K + K +SDK ++ ++ ++E Q EK+ K
Sbjct: 485 SKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQ----EKQHK 540
Query: 440 EEKKPI 445
+ + +
Sbjct: 541 NKDETV 546
Score = 76.6 bits (187), Expect = 5e-14
Identities = 58/179 (32%), Positives = 90/179 (50%), Gaps = 13/179 (7%)
Query: 211 KSDTSSKEIEEAMKRVREAQS---LISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHR 267
+ + KE E + +R +E +S + + DK + + R + S+ ++ + S SR R
Sbjct: 374 RGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRER 433
Query: 268 RSRSRSRRRSHSK-SRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTP 326
+ RSRSR R+ K SRSR + KS + + + +RSRS S+ R E K KKR +P
Sbjct: 434 KHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVE-KSKKREHSP 492
Query: 327 PKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKK-KDKDK 384
K +SR SR + R R S K +S K RS S + +EK+ K+KD+
Sbjct: 493 SKE-----KSRKRSRSKERSHKRD--HSDSKDQSDKHDRRRSQSIEQESQEKQHKNKDE 544
Score = 40.0 bits (92), Expect = 0.005
Identities = 35/112 (31%), Positives = 58/112 (51%), Gaps = 12/112 (10%)
Query: 203 AGLVSPSLKSDTSSKEIEEAMKRV-REAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTP 261
AG S S + SSK E+ ++ + ++S + +K +KR HS S+ +SR+R +
Sbjct: 444 AGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKR-S- 501
Query: 262 SSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDK 313
RS+ RS +R HS S+ +S RRRS S E+ + + K +D+
Sbjct: 502 ------RSKERSHKRDHSDSKD--QSDKHDRRRSQSIEQESQEKQ-HKNKDE 544
>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
Length = 2426
Score = 100 bits (249), Expect = 3e-21
Identities = 71/210 (33%), Positives = 103/210 (49%), Gaps = 5/210 (2%)
Query: 206 VSPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSR 265
V + + +K ++ K + SL S + E K R S SRSR R+ S S+
Sbjct: 1796 VKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSK 1855
Query: 266 HRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRS---RSTSKTRDKKKEDKEKKR 322
RS++RSR RS + RS R R RRS S+E+ +RS RS S+ R +K+ R
Sbjct: 1856 SHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNR 1915
Query: 323 SKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDK 382
+S + +RRSRS + RRRRSRS R SP R+ SR+PS R ++
Sbjct: 1916 KTVRARSRTPSRRSRSHT-PSRRRRSRSVGRRRSFSISPSRR-SRTPSRRSRTPSRRSRT 1973
Query: 383 DKERSRDERERSTSKKKKSKDKEKDRERKS 412
RSR RS + ++S+ + R +S
Sbjct: 1974 PSRRSRTPSRRSRTPSRRSRTPSRRRRSRS 2003
Score = 99.0 bits (245), Expect = 9e-21
Identities = 84/245 (34%), Positives = 121/245 (49%), Gaps = 39/245 (15%)
Query: 209 SLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHR- 267
SL+S + + E R R ++S A K + R +RSRSRSRRRR S SR +
Sbjct: 1821 SLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKS 1880
Query: 268 -----------------RSRSRSRRRSHSKSRSRR-----RSKSP-RRRRSHSRERGRRS 304
RS+SR R+R S SR R RS++P RR RSH+ R RRS
Sbjct: 1881 RGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRS 1940
Query: 305 RSTSKTRD-----KKKEDKEKKRSKTPP-KSYSTARRSRSASRERR--RRRSRSGTRSPK 356
RS + R ++ +RS+TP +S + +RRSR+ SR R RRSR+ +R +
Sbjct: 1941 RSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRR-R 1999
Query: 357 KPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDK 416
+ RS R+ S S SP R ++ + R RS ++K+S+ E+ R K +D
Sbjct: 2000 RSRSVVRRRSFSISPVRLRRSRTP------LRRRFSRSPIRRKRSRSSERGRSPKRLTDL 2053
Query: 417 DVKQV 421
D Q+
Sbjct: 2054 DKAQL 2058
Score = 65.9 bits (159), Expect = 8e-11
Identities = 45/189 (23%), Positives = 87/189 (46%), Gaps = 13/189 (6%)
Query: 252 RSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTR 311
R RS SS R S S S + + + + + +++ +R++G +
Sbjct: 1763 RDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEK-------- 1814
Query: 312 DKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSP 371
+KK++ + RSK S +R+ S SR R R+RS K RS R SRS
Sbjct: 1815 EKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKS----KSHRSQTRSRSRSRRR 1870
Query: 372 RRHKKEKKKDKDKER-SRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQ 430
RR + + K + + S+++R+RS + KS+++++ R ++ K V+ +R +
Sbjct: 1871 RRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSR 1930
Query: 431 GYDSEKEKK 439
+ + ++
Sbjct: 1931 SHTPSRRRR 1939
Score = 44.3 bits (103), Expect = 3e-04
Identities = 29/154 (18%), Positives = 58/154 (37%), Gaps = 6/154 (3%)
Query: 303 RSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPK 362
R RS + ++ + S Y + + + ++ ++R KK S
Sbjct: 1763 RDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSL 1822
Query: 363 RKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVT 422
R S+ HK K+ + + R+R +S S + +++ + + R R+ S +
Sbjct: 1823 RSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSR------S 1876
Query: 423 RDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECS 456
R + EK K+ K ++ K K S
Sbjct: 1877 RSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSS 1910
Score = 42.4 bits (98), Expect = 0.001
Identities = 76/301 (25%), Positives = 113/301 (37%), Gaps = 78/301 (25%)
Query: 207 SPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRH 266
+PS +S T S+ +R R + +RR SRS R RR + S R
Sbjct: 1959 TPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVR-RRSFSISPVRL 2017
Query: 267 RRSRSRSRRRSHSKSRSRRRSKSP-RRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKT 325
RRSR+ RRR S+SP RR+RS S ERGR K+ D +K +
Sbjct: 2018 RRSRTPLRRRF---------SRSPIRRKRSRSSERGR--------SPKRLTDLDKAQLLE 2060
Query: 326 PPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKE 385
K+ + A +++ P P K P+P +EK K
Sbjct: 2061 IAKANAAAMCAKAG-----------------VPLPPNLK----PAPPPTIEEKVAKKSGG 2099
Query: 386 RSRDERERSTSKKKKSKDKEKDRERKSESDKDV---KQVTRDYDEEEQGYDSEKEKKEEK 442
+ +E + +SK+ D DV K D +EEE + K E
Sbjct: 2100 ATIEELTEKCKQIAQSKE-----------DDDVIVNKPHVSDEEEEEPPFYHHPFKLSEP 2148
Query: 443 KPI---------ETGSPK-----TKECSVEKGTGDSLRES----------KVNGDDHHEE 478
KPI + PK TKE V G+ +E+ + NG+++ ++
Sbjct: 2149 KPIFFNLNIAAAKPTPPKSQVTLTKEFPVSSGSQHRKKEADSVYGEWVPVEKNGEENKDD 2208
Query: 479 D 479
D
Sbjct: 2209 D 2209
Score = 37.7 bits (86), Expect = 0.024
Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 2/88 (2%)
Query: 373 RHKKEKKKDK-DKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQG 431
+ KK K +DK +KE+ RD RS SK+ KS + K R+R SES ++ +
Sbjct: 1802 KSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSE-HKSRKRTSESRSRARKRSSKSKSHRSQ 1860
Query: 432 YDSEKEKKEEKKPIETGSPKTKECSVEK 459
S + ++ + S SV K
Sbjct: 1861 TRSRSRSRRRRRSSRSRSKSRGRRSVSK 1888
Score = 32.0 bits (71), Expect = 1.3
Identities = 16/60 (26%), Positives = 33/60 (55%), Gaps = 3/60 (5%)
Query: 385 ERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKP 444
++S+ ++ KKKK K+KEK +R+ E + + T+ +D+ +S+ K + +P
Sbjct: 106 KKSKKHKKHKNKKKKKKKEKEKKYKRQPE---ESESKTKSHDDGNIDLESDSFLKFDSEP 162
Score = 31.2 bits (69), Expect = 2.2
Identities = 25/114 (21%), Positives = 47/114 (41%), Gaps = 1/114 (0%)
Query: 299 ERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKP 358
E + + + R E+ +K + T R + +E R+ ++
Sbjct: 42 EGNQAGDAAASARSLPNEEIVQKIEEVLSGVLDTELRYKPDLKEGSRKSRCVSVQTDPTD 101
Query: 359 RSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKS 412
P +K S+ ++KK+KKK + +++ + + E S SK K D D E S
Sbjct: 102 EIPTKK-SKKHKKHKNKKKKKKKEKEKKYKRQPEESESKTKSHDDGNIDLESDS 154
>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
Length = 2303
Score = 100 bits (249), Expect = 3e-21
Identities = 71/210 (33%), Positives = 103/210 (49%), Gaps = 5/210 (2%)
Query: 206 VSPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSR 265
V + + +K ++ K + SL S + E K R S SRSR R+ S S+
Sbjct: 1796 VKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSK 1855
Query: 266 HRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRS---RSTSKTRDKKKEDKEKKR 322
RS++RSR RS + RS R R RRS S+E+ +RS RS S+ R +K+ R
Sbjct: 1856 SHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNR 1915
Query: 323 SKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDK 382
+S + +RRSRS + RRRRSRS R SP R+ SR+PS R ++
Sbjct: 1916 KTVRARSRTPSRRSRSHT-PSRRRRSRSVGRRRSFSISPSRR-SRTPSRRSRTPSRRSRT 1973
Query: 383 DKERSRDERERSTSKKKKSKDKEKDRERKS 412
RSR RS + ++S+ + R +S
Sbjct: 1974 PSRRSRTPSRRSRTPSRRSRTPSRRRRSRS 2003
Score = 99.0 bits (245), Expect = 9e-21
Identities = 84/245 (34%), Positives = 121/245 (49%), Gaps = 39/245 (15%)
Query: 209 SLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHR- 267
SL+S + + E R R ++S A K + R +RSRSRSRRRR S SR +
Sbjct: 1821 SLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKS 1880
Query: 268 -----------------RSRSRSRRRSHSKSRSRR-----RSKSP-RRRRSHSRERGRRS 304
RS+SR R+R S SR R RS++P RR RSH+ R RRS
Sbjct: 1881 RGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRS 1940
Query: 305 RSTSKTRD-----KKKEDKEKKRSKTPP-KSYSTARRSRSASRERR--RRRSRSGTRSPK 356
RS + R ++ +RS+TP +S + +RRSR+ SR R RRSR+ +R +
Sbjct: 1941 RSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRR-R 1999
Query: 357 KPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDK 416
+ RS R+ S S SP R ++ + R RS ++K+S+ E+ R K +D
Sbjct: 2000 RSRSVVRRRSFSISPVRLRRSRTP------LRRRFSRSPIRRKRSRSSERGRSPKRLTDL 2053
Query: 417 DVKQV 421
D Q+
Sbjct: 2054 DKAQL 2058
Score = 65.9 bits (159), Expect = 8e-11
Identities = 45/189 (23%), Positives = 87/189 (46%), Gaps = 13/189 (6%)
Query: 252 RSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTR 311
R RS SS R S S S + + + + + +++ +R++G +
Sbjct: 1763 RDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEK-------- 1814
Query: 312 DKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSP 371
+KK++ + RSK S +R+ S SR R R+RS K RS R SRS
Sbjct: 1815 EKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKS----KSHRSQTRSRSRSRRR 1870
Query: 372 RRHKKEKKKDKDKER-SRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQ 430
RR + + K + + S+++R+RS + KS+++++ R ++ K V+ +R +
Sbjct: 1871 RRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSR 1930
Query: 431 GYDSEKEKK 439
+ + ++
Sbjct: 1931 SHTPSRRRR 1939
Score = 44.3 bits (103), Expect = 3e-04
Identities = 29/154 (18%), Positives = 58/154 (37%), Gaps = 6/154 (3%)
Query: 303 RSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPK 362
R RS + ++ + S Y + + + ++ ++R KK S
Sbjct: 1763 RDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSL 1822
Query: 363 RKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVT 422
R S+ HK K+ + + R+R +S S + +++ + + R R+ S +
Sbjct: 1823 RSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSR------S 1876
Query: 423 RDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECS 456
R + EK K+ K ++ K K S
Sbjct: 1877 RSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSS 1910
Score = 42.4 bits (98), Expect = 0.001
Identities = 76/301 (25%), Positives = 113/301 (37%), Gaps = 78/301 (25%)
Query: 207 SPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRH 266
+PS +S T S+ +R R + +RR SRS R RR + S R
Sbjct: 1959 TPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVR-RRSFSISPVRL 2017
Query: 267 RRSRSRSRRRSHSKSRSRRRSKSP-RRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKT 325
RRSR+ RRR S+SP RR+RS S ERGR K+ D +K +
Sbjct: 2018 RRSRTPLRRRF---------SRSPIRRKRSRSSERGR--------SPKRLTDLDKAQLLE 2060
Query: 326 PPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKE 385
K+ + A +++ P P K P+P +EK K
Sbjct: 2061 IAKANAAAMCAKAG-----------------VPLPPNLK----PAPPPTIEEKVAKKSGG 2099
Query: 386 RSRDERERSTSKKKKSKDKEKDRERKSESDKDV---KQVTRDYDEEEQGYDSEKEKKEEK 442
+ +E + +SK+ D DV K D +EEE + K E
Sbjct: 2100 ATIEELTEKCKQIAQSKE-----------DDDVIVNKPHVSDEEEEEPPFYHHPFKLSEP 2148
Query: 443 KPI---------ETGSPK-----TKECSVEKGTGDSLRES----------KVNGDDHHEE 478
KPI + PK TKE V G+ +E+ + NG+++ ++
Sbjct: 2149 KPIFFNLNIAAAKPTPPKSQVTLTKEFPVSSGSQHRKKEADSVYGEWVPVEKNGEENKDD 2208
Query: 479 D 479
D
Sbjct: 2209 D 2209
Score = 37.7 bits (86), Expect = 0.024
Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 2/88 (2%)
Query: 373 RHKKEKKKDK-DKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQG 431
+ KK K +DK +KE+ RD RS SK+ KS + K R+R SES ++ +
Sbjct: 1802 KSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSE-HKSRKRTSESRSRARKRSSKSKSHRSQ 1860
Query: 432 YDSEKEKKEEKKPIETGSPKTKECSVEK 459
S + ++ + S SV K
Sbjct: 1861 TRSRSRSRRRRRSSRSRSKSRGRRSVSK 1888
Score = 32.0 bits (71), Expect = 1.3
Identities = 16/60 (26%), Positives = 33/60 (55%), Gaps = 3/60 (5%)
Query: 385 ERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKP 444
++S+ ++ KKKK K+KEK +R+ E + + T+ +D+ +S+ K + +P
Sbjct: 106 KKSKKHKKHKNKKKKKKKEKEKKYKRQPE---ESESKTKSHDDGNIDLESDSFLKFDSEP 162
Score = 31.2 bits (69), Expect = 2.2
Identities = 25/114 (21%), Positives = 47/114 (41%), Gaps = 1/114 (0%)
Query: 299 ERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKP 358
E + + + R E+ +K + T R + +E R+ ++
Sbjct: 42 EGNQAGDAAASARSLPNEEIVQKIEEVLSGVLDTELRYKPDLKEGSRKSRCVSVQTDPTD 101
Query: 359 RSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKS 412
P +K S+ ++KK+KKK + +++ + + E S SK K D D E S
Sbjct: 102 EIPTKK-SKKHKKHKNKKKKKKKEKEKKYKRQPEESESKTKSHDDGNIDLESDS 154
>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
Length = 290
Score = 98.2 bits (243), Expect = 1e-20
Identities = 60/202 (29%), Positives = 99/202 (49%), Gaps = 15/202 (7%)
Query: 240 DKKEEKRRHSRSRSRSRRRRTPSSSRHRRSR-----SRSRRRSHSKSRSRRRSKSPRRRR 294
+K E++R R R R RRR+ ++R+R R R R K R R R + R R
Sbjct: 86 EKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERER 145
Query: 295 SHSRERGRRSRSTSKTRDKKKE---DKEKKRSKTPPKSYSTAR---RSRSASRERRRRRS 348
RE+ R R T K RD ++E ++E+ R + K T R R R +ER R+
Sbjct: 146 DRDREK-ERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTD 204
Query: 349 RSGTRSPKKPRSPKRKLSRS---PSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKE 405
R R K +R+ R + RR ++++ +D+ KER R+ + KK++ K+++
Sbjct: 205 RERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERK 264
Query: 406 KDRERKSESDKDVKQVTRDYDE 427
K+R+ K + +K + R + E
Sbjct: 265 KERKEKKKEEKRREDKKRKWGE 286
Score = 88.6 bits (218), Expect = 1e-17
Identities = 64/236 (27%), Positives = 120/236 (50%), Gaps = 22/236 (9%)
Query: 251 SRSRSRRRRTPSS----SRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRS 306
SR R + +P S H+ + R+R + R + + R R+ RER R+ +
Sbjct: 50 SRGRLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRK-RDRERRRKEKE 108
Query: 307 TSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLS 366
T++ RD++K+ + ++ + + R R RER R R + R +K R +R+ +
Sbjct: 109 TNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRE-T 167
Query: 367 RSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKS------ESDKDVKQ 420
+ R ++EK+K+++ ER RD + + ++++ D+E+DR+RK+ E+D++ ++
Sbjct: 168 ETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGER 227
Query: 421 VT-------RDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESK 469
T RD D ++ D E+++KEE+K E + KE EK + RE K
Sbjct: 228 ETDRRRERQRDRDRGKE-RDRERDRKEERKK-ERKKERKKE-RKEKKKEEKRREDK 280
Score = 85.5 bits (210), Expect = 1e-16
Identities = 63/205 (30%), Positives = 96/205 (46%), Gaps = 28/205 (13%)
Query: 217 KEIEEAMKRVREAQSLISAAIEPDKKEEKRR-HSRSRSRSRRRRTPSSSRHRRSRSRSRR 275
KE E R RE Q+ IE D++ EK++ R R R R R R R + R
Sbjct: 105 KEKETNRNRDREKQT----EIERDREREKQKGRERERDRGRER------ERDRDREKERE 154
Query: 276 RSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARR 335
R K R +R R R RE+ ++ R T + RD+++ D EK+R + + R
Sbjct: 155 RQTEKDRDGQRETETERERDREREK-QKERETERDRDRQR-DTEKERERQTDRERD---R 209
Query: 336 SRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSR-DERERS 394
R ER+R R G R + R R+ +++ K++D+ER R +ER++
Sbjct: 210 QRKTQTERQRETDREGERETDRRRE-----------RQRDRDRGKERDRERDRKEERKKE 258
Query: 395 TSKKKKSKDKEKDRERKSESDKDVK 419
K++K + KEK +E K DK K
Sbjct: 259 RKKERKKERKEKKKEEKRREDKKRK 283
Score = 67.4 bits (163), Expect = 3e-11
Identities = 47/205 (22%), Positives = 101/205 (49%), Gaps = 10/205 (4%)
Query: 281 SRSRRRSK-SPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSA 339
SR R S+ SPR + + RD+ +E EK+R + + R+ +
Sbjct: 50 SRGRLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKET 109
Query: 340 SRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHK---KEKKKDKDKERSRDERERSTS 396
+R R R + R ++ + R+ R R + +EK++++ E+ RD + + +
Sbjct: 110 NRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETET 169
Query: 397 KKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECS 456
++++ +++EK +ER++E D+D ++ T E+E+ +++E+ ++K +T + +
Sbjct: 170 ERERDREREKQKERETERDRDRQRDT----EKERERQTDRERDRQRK-TQTERQRETDRE 224
Query: 457 VEKGTGDSLRESKVNGDDHHEEDMD 481
E+ T D RE + + D E D +
Sbjct: 225 GERET-DRRRERQRDRDRGKERDRE 248
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 97.4 bits (241), Expect = 3e-20
Identities = 69/262 (26%), Positives = 126/262 (48%), Gaps = 32/262 (12%)
Query: 238 EPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRS--RSRRRSHSKSRSRRRSKSPRRRRS 295
E D +++ R S R R R + R +R S R + R+ R RR + R
Sbjct: 610 ERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVD 669
Query: 296 HSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSP 355
R+ R R + RD+++E +E++R + R R RE R R+R R
Sbjct: 670 DRRDERARERDRERERDRERE-RERERERD---------REREKERELERERARERERER 719
Query: 356 KKPRSPKRKLSRSPSPRRHK-KEKKKDKDKERSRDERERSTSKKK-KSKDKEKDRERKSE 413
+K R +R R R + +E+ ++K++ER R+ERER +++ + +++E++RER E
Sbjct: 720 EKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERARE 779
Query: 414 SDKDVKQVTRDYDEEEQGYDSEKEKKEE-----------------KKPIETGSPKTKECS 456
DK+ ++ RD++++++G D +EK+EE K+ GSP ++
Sbjct: 780 RDKE-RERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSP 838
Query: 457 VEKGTGDSLRESKVNGDDHHEE 478
+ ++ +GDD +E+
Sbjct: 839 KRRREHSPDSDAYNSGDDKNEK 860
Score = 91.3 bits (225), Expect = 2e-18
Identities = 83/288 (28%), Positives = 124/288 (43%), Gaps = 46/288 (15%)
Query: 218 EIEEAMKRVREAQSLISAAIEPDKKEEKRR-HSRSRSRSRRR-RTPSSSRHRRSRSRSRR 275
E E A +R RE + E D++ ++ R H R R R R R R R R R R R
Sbjct: 708 ERERAREREREREK------ERDRERDRDRDHDRERERERERDREKEREREREERERERE 761
Query: 276 RSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARR 335
R + R R R + R R RER R K RD ++E +E+ R P+ R+
Sbjct: 762 RERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERK 821
Query: 336 SRSASR-----------ERRRRRS------RSGTRSPKKPR------SPKRKLSRSPS-- 370
S+ R +RRR S SG +K R P+ S SPS
Sbjct: 822 SKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHL 881
Query: 371 ----PRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQ------ 420
R K+E +K + KE SR E+ +K S DK++++ ES + Q
Sbjct: 882 TEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHH 941
Query: 421 VTRDYDEEEQGYDSEKEK-KEEKKPIETGSPKTKECSVEKGTGDSLRE 467
+ D + ++ +D K+K K +KKPI+ K + +E+G ++ E
Sbjct: 942 QSEDRETSDRAHDENKKKAKIQKKPIK--KKKEDDVGIERGNIETTSE 987
Score = 89.4 bits (220), Expect = 7e-18
Identities = 77/297 (25%), Positives = 122/297 (41%), Gaps = 49/297 (16%)
Query: 237 IEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSH 296
+E D++ E+RR R R R R R R R R + R R + + R R+
Sbjct: 654 LERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERAR 713
Query: 297 SRERGR---RSRSTSKTRDKKKE-DKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGT 352
RER R R R + RD +E ++E++R + + R R RER R R R
Sbjct: 714 EREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERE 773
Query: 353 RSPKKPRSPKRKLSR-------SPSPRRHKKEK-KKDKDKERSRDERE------------ 392
R + R +R+ R RR K+E+ ++D++ DER+
Sbjct: 774 RERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPS 833
Query: 393 -RSTSKKKKSKDKEKDR----ERKSESDKDVKQVTRDYD----------EEEQG----YD 433
R + K+++ + D + K+E + + QV R + E+ QG D
Sbjct: 834 PRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEED 893
Query: 434 SEKEKKEEKKPIETGSPKTKECSVEKGTGDS--LRESKVNGDD----HHEEDMDMSD 484
+ E+KE + E K K SV+K + L S++ D H ED + SD
Sbjct: 894 RKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSD 950
Score = 77.8 bits (190), Expect = 2e-14
Identities = 67/261 (25%), Positives = 116/261 (44%), Gaps = 20/261 (7%)
Query: 241 KKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRER 300
++E R R+ SR+ R + R RSR R SR R S+ + +
Sbjct: 535 REESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHD 594
Query: 301 GRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRS---RSGTRSPKK 357
+RS+ RD+ E + +++ R R +RER +R S R R+ +
Sbjct: 595 SWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDEL 654
Query: 358 PRSPKRKLSRSPSPRRHKKEKKKDKDKERSRD-------ERERSTSKKKK---SKDKEKD 407
R +R+ R + E+ +++D+ER RD ERER ++K+ +++ ++
Sbjct: 655 ERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERARE 714
Query: 408 RERKSESDKD-VKQVTRDYD---EEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGD 463
RER+ E ++D + RD+D E E+ D EKE++ E++ E + +E E+ +
Sbjct: 715 REREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERER---E 771
Query: 464 SLRESKVNGDDHHEEDMDMSD 484
RE D E D D
Sbjct: 772 RERERARERDKERERQRDWED 792
Score = 76.6 bits (187), Expect = 5e-14
Identities = 68/264 (25%), Positives = 118/264 (44%), Gaps = 25/264 (9%)
Query: 199 NHVAAGLVSPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRR 258
+H + L SPS S S + + KRV + S ++ ++ S + R+
Sbjct: 1200 SHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSGS----------RDREKTKSLEITGERKS 1249
Query: 259 RTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDK 318
R R SRS S R S+S S RRS R+ HSR SR + RD+ + D+
Sbjct: 1250 RIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDR 1309
Query: 319 EKKRSKTPPKSYSTARRS-----RSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRR 373
E++R + + R + R+ R+R R R R R ++ +R+ S S
Sbjct: 1310 ERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRERERLISDS--- 1366
Query: 374 HKKEKKKDKDKERSRDERERSTSKKKKSK---DKEKDRERKSESDKDVKQVTRDYD-EEE 429
E+ +D+D++R+ + + + K+ ++K + E+D E S + + D D
Sbjct: 1367 --VERDRDRDRDRTFESSQIESVKRCEAKLEGEHERDLESTSRDSLALDKERMDKDLGSV 1424
Query: 430 QGYDSEKEKKEEKKPIETGSPKTK 453
QG++ E K E + +E G ++K
Sbjct: 1425 QGFE-ETNKSERTESLEAGDDESK 1447
Score = 73.6 bits (179), Expect = 4e-13
Identities = 70/233 (30%), Positives = 109/233 (46%), Gaps = 36/233 (15%)
Query: 246 RRHSRSRSRSRRRRTPSSSRHRR-----SRSRSRRRSHSKSRSRRRSKSPRRRRSHSRER 300
+RHS S RR+RTPS S R RS S SHS S S +R +SP R RS RE+
Sbjct: 343 QRHSPS---PRRKRTPSPSYQRTLTPPLRRSASPYPSHSLS-SPQRKQSPPRHRSPMREK 398
Query: 301 GRRSRS-TSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPR 359
GR TS++ D++ E +E R K R + + ER + +S +R + R
Sbjct: 399 GRHDHERTSQSHDRRHERREDTRGKRD--------REKDSREEREYEQDQSSSRDHRDDR 450
Query: 360 SPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKK--SKDKEKDRE-RKSESDK 416
P+ R +++ + +D+ RD R+ S++ + S+D ++ R+ R S S +
Sbjct: 451 EPR--------DGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTR 502
Query: 417 DVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESK 469
D DY + E G D+ +KE+ P E+ S E + ES+
Sbjct: 503 D----AHDYRDRE-GRDT--HRKEDTYPEESRSYGRNHLREESSRTEIRNESR 548
Score = 71.2 bits (173), Expect = 2e-12
Identities = 90/378 (23%), Positives = 149/378 (39%), Gaps = 57/378 (15%)
Query: 115 IPDEAKALSLLAPANAVAGLLPGGGLLPTPNPLTQI--GAVPLAALGAPTLDPALAALGL 172
+PD + A A PG TP+PL+ + P+A A T+ LAA
Sbjct: 1072 VPDRTEVTEAEHTATATT---PGS----TPSPLSSLLPPPPPVATATATTVPATLAATTA 1124
Query: 173 PGANLNSQSLAADQLLKLMSTVDPKLNHVAAGLVSPSLKSDTSSKEIEEAMKRVREAQSL 232
A S S + +T N+ A S T +++E + +AQ
Sbjct: 1125 AAATSFSTSAIT---ISTSATPTNTTNNTFANEDSHRKCHRTRVEKVETPHVTIEDAQHR 1181
Query: 233 ISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRS--HSKSRSRRRSKS- 289
+ R +RS + R R + S HR +S R+ HS SR R ++KS
Sbjct: 1182 KPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSGSRDREKTKSL 1241
Query: 290 ----PRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRR 345
R+ R +RG SRSTS R + ++ S + SRS S + R
Sbjct: 1242 EITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQV----HSRSGSFDSRD 1297
Query: 346 RRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKE 405
R + R +R+ R+ + ++ DKD R+RD + + +E
Sbjct: 1298 RLQERDRYEHDRERERERR-----DTRQREWDRDADKDWPRNRD----------RDRLRE 1342
Query: 406 KDRERKSESDKDVKQVTRDY--DEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGD 463
++RER+ + +D+ + D E+ D ++++ E IE+ K C
Sbjct: 1343 RERERERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIES----VKRC-------- 1390
Query: 464 SLRESKVNGDDHHEEDMD 481
E+K+ G+ HE D++
Sbjct: 1391 ---EAKLEGE--HERDLE 1403
Score = 68.2 bits (165), Expect = 2e-11
Identities = 61/255 (23%), Positives = 115/255 (45%), Gaps = 27/255 (10%)
Query: 240 DKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRE 299
+++ EKR RS S + + +P SSRH S S+S S +R S SPRR+R+ S
Sbjct: 305 ERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSG------SSIQRHSPSPRRKRTPSPS 358
Query: 300 RGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPR 359
R + + S P S S+ +R +S R R R + + +
Sbjct: 359 YQRTLTPPLR----------RSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQ 408
Query: 360 SPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESD-KDV 418
S R+ R R K++++KD +ER ++ + S+ + ++ R+R+ D +D
Sbjct: 409 SHDRRHERREDTRG-KRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDR 467
Query: 419 KQV--TRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLR-------ESK 469
+++ +RD + + D ++ KE + P ++ S + ++ D+ R ES+
Sbjct: 468 RELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESR 527
Query: 470 VNGDDHHEEDMDMSD 484
G +H E+ ++
Sbjct: 528 SYGRNHLREESSRTE 542
Score = 60.5 bits (145), Expect = 3e-09
Identities = 76/323 (23%), Positives = 128/323 (39%), Gaps = 67/323 (20%)
Query: 217 KEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRR 276
+E E +R RE + A E DK+ E++R + + R R R R+
Sbjct: 758 RERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGH 817
Query: 277 SHSKSRSRRRSK-------SPRRRRSHSRE---------------------RGRRSRSTS 308
KS+ R R++ SP+RRR HS + R + SRS S
Sbjct: 818 DERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLS 877
Query: 309 K---TRDK----KKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRS- 360
T D+ K+ED++ +R ++ + + + +S +++R ++ S + +
Sbjct: 878 PSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDI 937
Query: 361 --PKRKLSRSPSPRRH-----------KKEKKKDKD---------KERSRDERERSTSKK 398
+ R S R H K KKK +D + S D + S K
Sbjct: 938 IGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKG 997
Query: 399 KKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVE 458
+K K EK R +KS+ D D+ +EE S+K++ PI T + C+ +
Sbjct: 998 QKKKSIEKKR-KKSKGDSDI-------SDEEAAQQSKKKRGPRTPPITTKEELVEMCNGK 1049
Query: 459 KG-TGDSLRESKVNGDDHHEEDM 480
G DS ++ D +ED+
Sbjct: 1050 NGILEDSQKKEDTAFSDWSDEDV 1072
Score = 60.1 bits (144), Expect = 4e-09
Identities = 74/313 (23%), Positives = 119/313 (38%), Gaps = 58/313 (18%)
Query: 224 KRVREAQSLISAAIEPDKKEEK-RRHSRSRSRSRRRRTPSSSRHRRSRSRSR-----RRS 277
KR RE S E D+ + R R R RR +R RR SR R
Sbjct: 423 KRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREM 482
Query: 278 HSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSR 337
SR + S+ PR RS R R T +KED + S++ +++ SR
Sbjct: 483 RDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTH--RKEDTYPEESRSYGRNHLREESSR 540
Query: 338 SASRERRRRRSRSGTRSPKKPRSPKR------KLSRSPS--------------------- 370
+ R R SRS R+ + RS R K SR
Sbjct: 541 TEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRS 600
Query: 371 --------PRRHKKEKKKDKDKERSRDERERSTSKKK----------KSKDKEKDRERKS 412
P R +++ +D ER ER+R ++++ + ++ E +R+ +
Sbjct: 601 SYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERR 660
Query: 413 ESDKDVKQVTRDYDEEEQGYDSEKEK---KEEKKPIETGSPKTKECSVEKGTG-DSLRES 468
E ++ V +V DE + D E+E+ +E ++ E + KE +E+ + RE
Sbjct: 661 E-ERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERARERERER 719
Query: 469 KVNGDDHHEEDMD 481
+ D + D D
Sbjct: 720 EKERDRERDRDRD 732
Score = 44.3 bits (103), Expect = 3e-04
Identities = 55/250 (22%), Positives = 89/250 (35%), Gaps = 57/250 (22%)
Query: 251 SRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKT 310
S R R R R R + + R+ S SP R+ S SR R R T
Sbjct: 72 SNYRRSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKES-SRGRHREKEDIKIT 130
Query: 311 RDKKKEDKEKK---------------------RSKTPPKSYSTARRSRSASRERRRRRSR 349
+++ E +E+ K R +E +R
Sbjct: 131 KERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENMEKREE 190
Query: 350 SGTRSPKKPRSPKRKLSRSPSPRRHKKE-KKKDKDKERSRDERERST------------- 395
+ P + KLS SPS R+ K K+K K S +++R T
Sbjct: 191 IIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRN 250
Query: 396 SKKKKSKDK------------------EKDRERKSESDKDVKQVTRDYDEEEQGYDSEKE 437
SK +SK K +K +E+ D+ +++ TR D +++G D E++
Sbjct: 251 SKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDR-IEEKTR--DGKDRGRDFERQ 307
Query: 438 KKEEKKPIET 447
+++ KP T
Sbjct: 308 REKRDKPRST 317
Score = 42.7 bits (99), Expect = 7e-04
Identities = 54/229 (23%), Positives = 88/229 (38%), Gaps = 50/229 (21%)
Query: 221 EAMKRVREAQSLISAAIEPDKKEEKRRHSRSRS--RSRRRRTPSSSRHRRSRSRSRRRS- 277
E KR E S P +KE R R + + + RTP S +R S
Sbjct: 99 EPQKRNTEESS------SPVRKESSRGRHREKEDIKITKERTPESEEENVEWETNRDDSD 152
Query: 278 ---------HSKSRSRRRSKSPRRRRSHSRERGRRSR--------STSKTRDK------- 313
H S +R K R +E + S R K
Sbjct: 153 NGDINYDYVHELSLEMKRQKIQRELMKLEQENMEKREEIIIKKEVSPEVVRSKLSPSPSL 212
Query: 314 KKEDKEKKRSKTPPKSYSTARRSRSAS--------RERRRRRSRSGTRSPKKPRSPKRKL 365
+K K KR K+ PKS S +++ R S ++R + ++S + P+ P P
Sbjct: 213 RKSSKSPKR-KSSPKSSSASKKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIP 271
Query: 366 SRSPSPRRHK-KEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSE 413
+++K K K KD+ +E++RD ++R +D E+ RE++ +
Sbjct: 272 EDIALGKKYKEKYKVKDRIEEKTRDGKDRG-------RDFERQREKRDK 313
Score = 39.7 bits (91), Expect = 0.006
Identities = 39/166 (23%), Positives = 69/166 (41%), Gaps = 18/166 (10%)
Query: 275 RRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTAR 334
RR + ++ S S RR S G + ST++T+ + KT Y
Sbjct: 5 RRKVTVENTKTISDSTSRRPSVFERLGPSTGSTAETQCRNW-------LKTGNCLYGNTC 57
Query: 335 RSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERS 394
R R + S + RSP++P R+ K K++D D E + E S
Sbjct: 58 RFVHGPSPRGKGYSSNYRRSPERPTGDLRE---------RMKNKRQDVDTEPQKRNTEES 108
Query: 395 TSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKE 440
+S + K+ + R R+ E K K+ T + +EE +++ ++ +
Sbjct: 109 SSPVR--KESSRGRHREKEDIKITKERTPESEEENVEWETNRDDSD 152
Score = 37.4 bits (85), Expect = 0.031
Identities = 50/212 (23%), Positives = 87/212 (41%), Gaps = 10/212 (4%)
Query: 264 SRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRS 323
S+ RR + ++ S S SRR S R S + R+ KT + + +
Sbjct: 2 SKIRRKVTVENTKTISDSTSRRPSVFERLGPSTGSTAETQCRNWLKTGNCLYGNTCRFVH 61
Query: 324 KTPP--KSYSTARRSRSASRERRRRRSRSGTRSPKKPRSP-KRKLSRSPSPRRHKKEKKK 380
P K YS+ R RS R R R + P KR S SP R + + +
Sbjct: 62 GPSPRGKGYSSNYR-RSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGR 120
Query: 381 DKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEE-EQGYDSEKEKK 439
++KE + +ER+ ++++ + E +R+ D D + DY E +K ++
Sbjct: 121 HREKEDIKITKERTPESEEENVEWETNRD-----DSDNGDINYDYVHELSLEMKRQKIQR 175
Query: 440 EEKKPIETGSPKTKECSVEKGTGDSLRESKVN 471
E K + K +E ++K + SK++
Sbjct: 176 ELMKLEQENMEKREEIIIKKEVSPEVVRSKLS 207
Score = 34.7 bits (78), Expect = 0.20
Identities = 33/176 (18%), Positives = 64/176 (36%), Gaps = 12/176 (6%)
Query: 308 SKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSR 367
SK R K + K S + + S R ++ + R+ ++ +
Sbjct: 2 SKIRRKVTVENTKTISDSTSRRPSVFERLGPSTGSTAETQCRNWLKTGNCLYGNTCRFVH 61
Query: 368 SPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDE 427
PSPR + ER + K++ D E + ES V++
Sbjct: 62 GPSPRGKGYSSNYRRSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRK------- 114
Query: 428 EEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDHHEEDMDMS 483
+S + + EK+ I+ +T E E ++ R+ NGD +++ ++S
Sbjct: 115 -----ESSRGRHREKEDIKITKERTPESEEENVEWETNRDDSDNGDINYDYVHELS 165
Score = 33.5 bits (75), Expect = 0.44
Identities = 39/165 (23%), Positives = 70/165 (42%), Gaps = 22/165 (13%)
Query: 211 KSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSR 270
K + E +E+ +R E Q L DK+ E+ S SR R H+
Sbjct: 890 KEEDRKPERKESSRRYEE-QELKEKVSSVDKQREQTEILES---SRMRAQDIIGHHQSED 945
Query: 271 SRSRRRSHSKSRSRRR-SKSPRRRRSHSR---ERGRRSRST------SKTRDKKKEDKEK 320
+ R+H +++ + + K P +++ ERG ++ S + +KK+ EK
Sbjct: 946 RETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEK 1005
Query: 321 KRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKL 365
KR K+ S + + S+++R G R+P P + K +L
Sbjct: 1006 KRKKSKGDSDISDEEAAQQSKKKR------GPRTP--PITTKEEL 1042
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 96.3 bits (238), Expect = 6e-20
Identities = 60/213 (28%), Positives = 109/213 (51%), Gaps = 20/213 (9%)
Query: 244 EKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRR--RRSHSRERG 301
E+ R +R ++ R + RR R + R+R K R R R K ++ R+ RER
Sbjct: 40 EREREIETRKEGKKERESERKKERREREK-RKREREKERKRERGKKEKKGERKKEERERK 98
Query: 302 RRSRSTS----KTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKK 357
+R R + ++K+K+ ++K+R +T + R+ ER+ R + R ++
Sbjct: 99 KRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKER 158
Query: 358 PRSPKRKLSR----SPSPRRHKKEKKKDKDKERSRDERERSTSKK---KKSKDKEKDRER 410
R ++K R R +KE+K+ K +ER+R ER++ +K ++ K+++K ER
Sbjct: 159 ERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEER 218
Query: 411 KSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKK 443
K E KD + ++ E+E+G ++E+KE KK
Sbjct: 219 KKERQKDRQ---TNWREKERG---KRERKERKK 245
Score = 84.7 bits (208), Expect = 2e-16
Identities = 48/198 (24%), Positives = 95/198 (47%), Gaps = 17/198 (8%)
Query: 249 SRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTS 308
S R R R T + R R + R + R R R K +R R ++G R +
Sbjct: 36 SEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKE-E 94
Query: 309 KTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRS 368
+ R K++ +KE K + K R+++ + R+ K+ + +RK R
Sbjct: 95 RERKKRRREKENKEGEEKEK--------------RKKKEKKERGRTSKEGKERERKEERK 140
Query: 369 PSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEE 428
R+ ++ KK++++KER + +ER ++K+ +KE++R+ K ++ ++ R ++
Sbjct: 141 REERKERERKKEEREKER--ERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKK 198
Query: 429 EQGYDSEKEKKEEKKPIE 446
E+ +E+K+E+K E
Sbjct: 199 ERERKERRERKKERKKKE 216
Score = 83.2 bits (204), Expect = 5e-16
Identities = 52/176 (29%), Positives = 84/176 (47%), Gaps = 12/176 (6%)
Query: 279 SKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRS 338
S+ R R R R+ RE R+ + + K++ +KE+KR + K R+
Sbjct: 36 SEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRER-GKKEKKGERKKEE 94
Query: 339 ASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKK 398
R++RRR + K+ R K K R + + K+ ++K++ K R ERER
Sbjct: 95 RERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERER----- 149
Query: 399 KKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKE 454
K +++EK+RERK ++ KQV +E + EKE+KE KK + KE
Sbjct: 150 -KKEEREKERERKERKKRERKQVGEKEEERK-----EKERKERKKRERNRKERKKE 199
Score = 82.8 bits (203), Expect = 6e-16
Identities = 46/195 (23%), Positives = 96/195 (49%), Gaps = 3/195 (1%)
Query: 280 KSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSA 339
+S R R + R+ +ER + + R+K+K ++EK+R + K R +
Sbjct: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
Query: 340 SRERRRRRSRSGTRSPKKP-RSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKK 398
++RRR + +K R K K R + + K+ ++K++ K R ERER ++
Sbjct: 95 RERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEER 154
Query: 399 KKSKDKE--KDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECS 456
+K ++++ K RERK +K+ ++ ++ E ++ + KE+K+E++ E K +
Sbjct: 155 EKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKK 214
Query: 457 VEKGTGDSLRESKVN 471
E+ + ++ + N
Sbjct: 215 KEERKKERQKDRQTN 229
Score = 53.5 bits (127), Expect = 4e-07
Identities = 40/145 (27%), Positives = 69/145 (47%), Gaps = 10/145 (6%)
Query: 340 SRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHK---KEKKKDKDKERSRDER---ER 393
S R R R + KK R +RK R +R + KE+K+++ K+ + ER ER
Sbjct: 36 SEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEER 95
Query: 394 STSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTK 453
K+++ K+ ++ E++ K+ K+ R E ++ E+ K+EE+K E K +
Sbjct: 96 ERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERER---KKE 152
Query: 454 ECSVEKGTGD-SLRESKVNGDDHHE 477
E E+ + RE K G+ E
Sbjct: 153 EREKERERKERKKRERKQVGEKEEE 177
Score = 49.7 bits (117), Expect = 6e-06
Identities = 34/137 (24%), Positives = 68/137 (49%), Gaps = 4/137 (2%)
Query: 348 SRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKD 407
++ G +S + R + + + R + KK+ +++E+ + ERE+ +K++ KEK
Sbjct: 30 TQPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREK--ERKRERGKKEKK 87
Query: 408 RERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRE 467
ERK E + K+ R E ++G + EK KK+EKK S + KE ++ R+
Sbjct: 88 GERKKEERERKKR--RREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERK 145
Query: 468 SKVNGDDHHEEDMDMSD 484
+ + E++ + +
Sbjct: 146 ERERKKEEREKERERKE 162
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 95.9 bits (237), Expect = 7e-20
Identities = 73/192 (38%), Positives = 99/192 (51%), Gaps = 24/192 (12%)
Query: 246 RRHSRSRSRSRRR---RTPSSSRHRRSRSRSRRRSHSKS--RSRRRSKSPRRR--RSHSR 298
RR SRSR+ +RRR RTP+ RSR+ +RRRS ++S R R RS+SP RR RS SR
Sbjct: 591 RRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSR 650
Query: 299 ERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKP 358
RR RS S+T + + + RS+TP ARRS + RR RS +R+P++
Sbjct: 651 TPARRGRSRSRTPAR----RGRSRSRTP------ARRSGRSRSRTPARRGRSRSRTPRRG 700
Query: 359 RSPKRKL-------SRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERK 411
RS R L SR+P R + K+K R+ R RS S + K + R +
Sbjct: 701 RSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSR 760
Query: 412 SESDKDVKQVTR 423
S S K +R
Sbjct: 761 SLSSPRSKAKSR 772
Score = 94.7 bits (234), Expect = 2e-19
Identities = 74/241 (30%), Positives = 116/241 (48%), Gaps = 23/241 (9%)
Query: 241 KKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRER 300
++ R R RS SR T SR R R R RS + +R R RS++P RRRS SR
Sbjct: 550 RRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTP 609
Query: 301 GRRSRSTSKTRDKKKED-----KEKKRSKTP------PKSYSTARRSRSASR-ERRRRRS 348
RR RS S+T +++ + + RS++P +S + ARR RS SR RR RS
Sbjct: 610 ARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRS 669
Query: 349 RSGTRSPKKPRS-----PKRKLSRSPSPRRHKKEK----KKDKDKERSRDERERS-TSKK 398
RS T + + RS +R SRS +PRR + ++ + R+ R RS +S +
Sbjct: 670 RSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSE 729
Query: 399 KKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVE 458
+K+K + R +S S ++K+ +R + S + K + + + + C +
Sbjct: 730 RKNKSRTSQRRSRSNSSPEMKK-SRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQ 788
Query: 459 K 459
K
Sbjct: 789 K 789
Score = 94.0 bits (232), Expect = 3e-19
Identities = 77/225 (34%), Positives = 111/225 (49%), Gaps = 20/225 (8%)
Query: 245 KRRHSRSRSRSRRRRTPSSSRHRRS-RSRSR---RRSHSKSRSRRRSKS-----PRRRRS 295
+R SRSR+ +RR R+ S + RRS RSRSR RR S+SR+ RR +S RR RS
Sbjct: 654 RRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRS 713
Query: 296 HSR--ERGRRSRSTSKTRDKKKEDKEKKRSKTPP---KSYSTARRSRSASRERRRRRSRS 350
HSR +R RS S+S+ ++K + + + RS + P KS ++RRSRS S R + +SR
Sbjct: 714 HSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRL 773
Query: 351 GTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRER 410
R SP K PRR + + K K R+ R RS+S K K K R
Sbjct: 774 SLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSS-SPPPKQKSKTPSR 832
Query: 411 KSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKEC 455
+S S + QG + + E ++ +P+ + C
Sbjct: 833 QSHSSSSPHPKVKSGTPPRQGSITSPQANE-----QSVTPQRRSC 872
Score = 93.6 bits (231), Expect = 4e-19
Identities = 83/261 (31%), Positives = 121/261 (46%), Gaps = 40/261 (15%)
Query: 245 KRRHSRSRS------RSRRRRTPSSSRHRRSRSRSRRR---SHSKSRSRR-RSKSPRRRR 294
KR HSRSRS RS +R S S RR RSRS +R S S++ RR RS+S RR R
Sbjct: 502 KRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGR 561
Query: 295 SHSRERGRRSRSTSKTRDKKKEDKEK------KRSKTPPKSYSTAR------RSRSASRE 342
SHSR R RS S+T ++ + + RS+TP + S +R RSRS +
Sbjct: 562 SHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPA 621
Query: 343 RRRRRSRSGTRSPKKPRSPKRKLSRSPS---PRRHKKEKKKDKDKERSRDE-------RE 392
RRR R+RS R + RSP R+ RS S RR + + + RSR R
Sbjct: 622 RRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRS 681
Query: 393 RSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQ-----GYDSEKEKK---EEKKP 444
RS + ++ + + + R + + + R + Q G SE++ K +++
Sbjct: 682 RSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRS 741
Query: 445 IETGSPKTKECSVEKGTGDSL 465
SP+ K+ + SL
Sbjct: 742 RSNSSPEMKKSRISSRRSRSL 762
Score = 90.9 bits (224), Expect = 2e-18
Identities = 84/265 (31%), Positives = 116/265 (43%), Gaps = 53/265 (20%)
Query: 246 RRHSRSRSRSRRRRTPSSS-RHRRSRSRS--RRRSHSKSRSRR----RSKSPRRR-RSHS 297
RR SRSR+ +RR R+ S + RRSR+RS RRRS S+S +RR RS++P RR RS S
Sbjct: 601 RRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRS 660
Query: 298 RERGRRSRSTSKT--------RDKKKEDKEKKRSKTPPKSYSTA---------------R 334
R RR RS S+T R + + + RS+TP + S + R
Sbjct: 661 RTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQR 720
Query: 335 RSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKER-------- 386
R RS S R+ +SR+ R + SP+ K SR S R + K K R
Sbjct: 721 RGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLS 780
Query: 387 -----------SRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSE 435
+ R RS S + K+K + R +S S KQ ++ + S
Sbjct: 781 GSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSP 840
Query: 436 KEKKEEKKPIETG---SPKTKECSV 457
K + P G SP+ E SV
Sbjct: 841 HPKVKSGTPPRQGSITSPQANEQSV 865
Score = 83.2 bits (204), Expect = 5e-16
Identities = 68/205 (33%), Positives = 109/205 (53%), Gaps = 32/205 (15%)
Query: 241 KKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRS-RRRSHSKSRSRR-----------RSK 288
K+++ H+ SR R R R+P++++ RSRSR+ +R HS+SRS + RS+
Sbjct: 468 KRDKSHSHTPSR-RMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSR 526
Query: 289 SPRRR---RSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPP-----KSYSTARRSRSAS 340
SP+RR RS R RSR+T + + + + S++P +S + ARR RS S
Sbjct: 527 SPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRS 586
Query: 341 RE--RRRRRSRSGTRSPKKPRSPKRK-LSRSPSP-RRHKKEKKKDKDKERSRD------- 389
R RRR RSR+ TR + R+P R+ SRS +P RR + + + + RSR
Sbjct: 587 RTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGR 646
Query: 390 ERERSTSKKKKSKDKEKDRERKSES 414
R R+ +++ +S+ + R +S S
Sbjct: 647 SRSRTPARRGRSRSRTPARRGRSRS 671
Score = 82.8 bits (203), Expect = 6e-16
Identities = 73/215 (33%), Positives = 100/215 (46%), Gaps = 24/215 (11%)
Query: 227 REAQSLISAAIEPDKKEEKRRHSRSRSRSR-----RRRTPSSSRHRRSRSRSRRRSHSKS 281
+ ++S S A + SR RSRSR RRR+ S + R RSRSR S+
Sbjct: 1862 KRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRR 1921
Query: 282 RSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASR 341
RSR R+ RRRS SR R RS S+T + + RS+TPP T RRSRS +
Sbjct: 1922 RSRSRTPPVTRRRSRSRTPTTRRRSRSRT---PPVTRRRSRSRTPP---VTRRRSRSRTS 1975
Query: 342 ERRRRRSRSGT--------RSPKKPRSPKRKLSR-SPSPRRHKKEKKKDKDKERSRDERE 392
RRRSRS T RS P + +R SR SP RR + + + RSR
Sbjct: 1976 PITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTP 2035
Query: 393 RSTSKKKKSKD----KEKDRERKSESDKDVKQVTR 423
K+ +S+ + + R R + + + +TR
Sbjct: 2036 LLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTR 2070
Score = 82.0 bits (201), Expect = 1e-15
Identities = 73/189 (38%), Positives = 97/189 (51%), Gaps = 32/189 (16%)
Query: 246 RRHSRSRS------RSRRRRTPSSSRHRRSRSR----SRRRSHSKSR--SRRRSK---SP 290
R+ SRSR+ RSR R +P++ HRRSRSR SRRRS S++ SRRRS+ S
Sbjct: 1849 RKRSRSRTSPAPWKRSRSRASPAT--HRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSV 1906
Query: 291 RRRRSHSRE---RGRRSRSTS------KTRDKKKEDKEKKRSKTPPKSYSTARRSRSASR 341
RRRS SR RRSRS + ++R + + + RS+TPP T RRSRS +
Sbjct: 1907 TRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPP---VTRRRSRSRTP 1963
Query: 342 ERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKS 401
RRRSRS T + RS R SP RR + + + RSR T ++ +S
Sbjct: 1964 PVTRRRSRSRTSPITRRRSRSR---TSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRS 2020
Query: 402 KDKEKDRER 410
+ R R
Sbjct: 2021 RTPPAIRRR 2029
Score = 80.9 bits (198), Expect = 2e-15
Identities = 65/218 (29%), Positives = 93/218 (42%), Gaps = 21/218 (9%)
Query: 246 RRHSRSRSRSR--RRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRER--- 300
RR RSRSRSR RRR S H RS +R S R R RS++P R SR R
Sbjct: 1799 RRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSP 1858
Query: 301 --GRRSRSTSKTRDKKKE-------DKEKKRSKTPPKSYSTARRSRSASRERRRRR---- 347
+RSRS + ++ + + RS+T P S +R S +R R R R
Sbjct: 1859 APWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPV 1918
Query: 348 SRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKD 407
SR +RS P + +R SR+P+ RR + + + RSR T ++ +S+
Sbjct: 1919 SRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPIT 1978
Query: 408 RERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPI 445
R R S VTR + + + P+
Sbjct: 1979 RRR---SRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPV 2013
Score = 80.1 bits (196), Expect = 4e-15
Identities = 81/277 (29%), Positives = 124/277 (44%), Gaps = 46/277 (16%)
Query: 175 ANLNSQSLAADQLLKLMSTVDPKLNHVAAGLVSPSLKSDTSSKEIEEAMKRVREAQSLIS 234
A L+ +S +A + S P+ SPS+ S +++ + +R
Sbjct: 1701 ARLSRRSRSASSSPETRSRTPPRHRR------SPSVSSPEPAEKSRSSRRR--------R 1746
Query: 235 AAIEPDKKEEKRRH----------SRSRSRSRRRRTPSSSRHRRS---RSRSRRRSHSKS 281
+A P K RR RSRSRSRR +T ++ R RS +S SRRR S+S
Sbjct: 1747 SASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRS 1806
Query: 282 RSR----RR------SKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYS 331
RSR RR S+SP R+ S SR RR R S+T +++ RS+T P +
Sbjct: 1807 RSRVTRRRRGGSGYHSRSPARQES-SRTSSRRRRGRSRT---PPTSRKRSRSRTSPAPWK 1862
Query: 332 TAR-RSRSASRERRRRR----SRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKER 386
+R R+ A+ R R R SR +RS P S +R SR+ RR + + + R
Sbjct: 1863 RSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRR 1922
Query: 387 SRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTR 423
SR T ++ +S+ R +S + ++ +R
Sbjct: 1923 SRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSR 1959
Score = 79.7 bits (195), Expect = 5e-15
Identities = 67/194 (34%), Positives = 93/194 (47%), Gaps = 28/194 (14%)
Query: 242 KEEKRRHSRSRSRSRRRRTPSSSRHRRSRS------RSRRRSHSKSRSRRRSKSP--RRR 293
++E R S R R R R P+S + RSR+ RSR R+ + R RS++P RR
Sbjct: 1827 RQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRR 1886
Query: 294 RSHSRE---RGRRSRS-TSKTRDKKKE-----DKEKKRSKTPP--------KSYSTARRS 336
RS SR RRSRS TS TR + + + + RS+TPP ++ +T RRS
Sbjct: 1887 RSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRS 1946
Query: 337 RSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTS 396
RS + RRRSRS T + RS R SP RR + + + RSR T
Sbjct: 1947 RSRTPPVTRRRSRSRTPPVTRRRSRSR---TSPITRRRSRSRTSPVTRRRSRSRTSPVTR 2003
Query: 397 KKKKSKDKEKDRER 410
++ +S+ R R
Sbjct: 2004 RRSRSRTSPVTRRR 2017
Score = 79.3 bits (194), Expect = 7e-15
Identities = 63/221 (28%), Positives = 100/221 (45%), Gaps = 20/221 (9%)
Query: 206 VSPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKR--RHSRSRSRSRRR----- 258
+SP SS E+++ + AQS ++ EP + R SRS S S+ R
Sbjct: 1591 LSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPE 1650
Query: 259 ---RTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKK 315
T SS H +RR S S + +S++P RRRS ++ R +
Sbjct: 1651 GSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSA 1710
Query: 316 EDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTR-----SPKKPRSPKRKLSRSPS 370
+ RS+TPP+ RRS S S +SRS R SP+ + +R S SP
Sbjct: 1711 SSSPETRSRTPPRH----RRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPK 1766
Query: 371 PRRHKKEKKKD-KDKERSRDERERSTSKKKKSKDKEKDRER 410
PR ++ + + ++K R+ R+RS S + S+ +++ R R
Sbjct: 1767 PRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSR 1807
Score = 77.4 bits (189), Expect = 3e-14
Identities = 61/202 (30%), Positives = 91/202 (45%), Gaps = 17/202 (8%)
Query: 221 EAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRR-RSHS 279
+ +R REA+ A EP K R S S R TP + ++ + R RR S S
Sbjct: 152 DPQRRAREAKQ---PAPEPPKPYSLVRESSSS----RSPTPKQKKKKKKKDRGRRSESSS 204
Query: 280 KSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSK--TPPKSYSTARRSR 337
R R++S ++ RS S + R+ RS + +K +DK++KRS+ TP A RS
Sbjct: 205 PRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRST 264
Query: 338 SASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSK 397
SA SRS +RS RSPSP ++ + E +R +S
Sbjct: 265 SADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSP 324
Query: 398 KKKSK-------DKEKDRERKS 412
+ +K DK+KD++ KS
Sbjct: 325 ETATKQPSSPYEDKDKDKKEKS 346
Score = 77.0 bits (188), Expect = 3e-14
Identities = 72/266 (27%), Positives = 113/266 (42%), Gaps = 30/266 (11%)
Query: 207 SPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRH 266
S S +S T K+ ++ K+ R +S S+ KK K++ RS S S++R+ H
Sbjct: 177 SSSSRSPTP-KQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRK------H 229
Query: 267 RRSRSRSRRRSHSKSRSRRRS--KSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSK 324
R +S+R+S K R R RS +P+ RR+H RSTS + +
Sbjct: 230 RSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAH--------RSTSADSASSSDTSRSRSRS 281
Query: 325 TPPKSYSTARRSRSASRERRRRR------SRSGTRSPKKPRSPKRKLSRSPSPRRHKKEK 378
K+++TA RS S RR S GT S ++P SP+ + SP K +
Sbjct: 282 AAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKD 341
Query: 379 KKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEK 438
KK+K R ERS++ + ER S + + T +E SE
Sbjct: 342 KKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPL--ATTPLSQEPVNPPSEASP 399
Query: 439 KEEKKPIETGSPKTKECSVEKGTGDS 464
++ P PK+ E + + +S
Sbjct: 400 TRDRSP-----PKSPEKLPQSSSSES 420
Score = 77.0 bits (188), Expect = 3e-14
Identities = 70/231 (30%), Positives = 107/231 (46%), Gaps = 27/231 (11%)
Query: 208 PSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRS--------RSRSRRRR 259
P +S SS E+ + R ++S S+ + + R S S +SRS RRR
Sbjct: 1686 PRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRR 1745
Query: 260 TPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKE 319
+SS ++ SR R K R +RS+S R RR +R RR RS S ++ +
Sbjct: 1746 RSASSPRTKTTSRRGRSPSPKPRGLQRSRS-RSRREKTRTTRRRDRSGSSQSTSRRRQRS 1804
Query: 320 KKRSKTPPK--------SYSTARR--SRSASRERRRRRSRSGTRSPKKPRSP------KR 363
+ RS+ + S S AR+ SR++SR RRR RSR+ S K+ RS KR
Sbjct: 1805 RSRSRVTRRRRGGSGYHSRSPARQESSRTSSR-RRRGRSRTPPTSRKRSRSRTSPAPWKR 1863
Query: 364 KLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSES 414
SR+ SP H++ + + R R S +++S+ + R+S S
Sbjct: 1864 SRSRA-SPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRS 1913
Score = 75.5 bits (184), Expect = 1e-13
Identities = 69/221 (31%), Positives = 107/221 (48%), Gaps = 26/221 (11%)
Query: 208 PSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEE---KRRHSRSRSR-------SRR 257
PS + +S++ E + R A+ ++ EP K +RR SRS SRR
Sbjct: 1647 PSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRR 1706
Query: 258 RRTPSSSRHRRSRSRSRRR---SHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKK 314
R+ SSS RSR+ R R S S +S+S RRRRS S R + + ++ K
Sbjct: 1707 SRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPK 1766
Query: 315 KEDKEKKRSKTP-PKSYSTARRSRSASRE---RRRRRSRSGTRSPKK--------PRSPK 362
++ RS++ K+ +T RR RS S + RRR+RSRS +R ++ RSP
Sbjct: 1767 PRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPA 1826
Query: 363 R-KLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSK 402
R + SR+ S RR + + ++RSR + K+ +S+
Sbjct: 1827 RQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSR 1867
Score = 75.5 bits (184), Expect = 1e-13
Identities = 75/234 (32%), Positives = 109/234 (46%), Gaps = 39/234 (16%)
Query: 207 SPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRH 266
SP+ + S+ + +R R S +S ++ + R S +R RSR R +P S R
Sbjct: 1869 SPATHRRSRSRTPLISRRRSRSRTSPVS------RRRSRSRTSVTRRRSRSRASPVSRRR 1922
Query: 267 RRSRSR--SRRRSHSK---SRSRRRSKSP--RRRRSHSR-----ERGRRSRSTSKTRDKK 314
RSR+ +RRRS S+ +R R RS++P RRRS SR R RSR++ TR +
Sbjct: 1923 SRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRS 1982
Query: 315 KE-----DKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGT----------RSPKKPR 359
+ + + RS+T P T RRSRS + RRRSRS T R+P PR
Sbjct: 1983 RSRTSPVTRRRSRSRTSP---VTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPR 2039
Query: 360 SPKRKLSRSPSPRRHKKEKKKDKDKERSRD-ERERSTSKKKKSKDKEKDRERKS 412
KR SRSP R + + + R R +++ + DR R +
Sbjct: 2040 --KRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSA 2091
Score = 75.1 bits (183), Expect = 1e-13
Identities = 63/187 (33%), Positives = 89/187 (47%), Gaps = 24/187 (12%)
Query: 238 EPDKKEEKRRHSRSR----SRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRR 293
E + +RR RSR SR R R S + +RSRSR+ +H +SRSR S RR
Sbjct: 1829 ESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRS 1888
Query: 294 RSH----SRERGRRSRSTSKTRDKKKED---KEKKRSKTPPKSYSTARRSRSASRERRRR 346
RS SR R R S ++ R + + + + RS+TPP T RRSRS + RRR
Sbjct: 1889 RSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPV---TRRRSRSRTPTTRRR 1945
Query: 347 RSRSGTRSPKKPRSPKRKLSRSPSP---RRHKKEKKKDKDKERSRDERERSTSKKKKSKD 403
S +R+P R + SRS +P RR + + + RSR T ++ +S+
Sbjct: 1946 ---SRSRTPPVTR----RRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRT 1998
Query: 404 KEKDRER 410
R R
Sbjct: 1999 SPVTRRR 2005
Score = 72.8 bits (177), Expect = 7e-13
Identities = 58/200 (29%), Positives = 90/200 (45%), Gaps = 18/200 (9%)
Query: 229 AQSLISAAIEPDKKEEKRRHSRSRSRSR-RRRTPSSSRHRRSRSRSRRRSHSKSRSRRRS 287
+ S S+ P K RR SRS + + RTP R RS R++ RSR S
Sbjct: 1652 SSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSAS 1711
Query: 288 KSPRRRRSHSRERGRRSRSTSKTRD-KKKEDKEKKRSKTPPKSYSTARRSRSAS---RER 343
SP RS + R RRS S S +K ++RS + P++ +T+RR RS S R
Sbjct: 1712 SSP-ETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGL 1770
Query: 344 RRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKER------------SRDER 391
+R RSRS + R R S + RR ++ + + + R +R E
Sbjct: 1771 QRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQES 1830
Query: 392 ERSTSKKKKSKDKEKDRERK 411
R++S++++ + + RK
Sbjct: 1831 SRTSSRRRRGRSRTPPTSRK 1850
Score = 72.4 bits (176), Expect = 9e-13
Identities = 67/223 (30%), Positives = 95/223 (42%), Gaps = 16/223 (7%)
Query: 245 KRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSR-SRRRSKS---PRRRRSHSRER 300
+R SRSRS RR R+ S + RR RS S +KSR S+RRS+S P ++ SR
Sbjct: 698 RRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKK--SRIS 755
Query: 301 GRRSRSTSKTRDKKKEDKEKKRSKT------PPKSYSTARRSRSASRERRRRRSRSGTRS 354
RRSRS S R K K +RS + KS + RRSRS S + + + RS
Sbjct: 756 SRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRS 815
Query: 355 PKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSES 414
P ++ S++PS + H K K + + TS + + R ES
Sbjct: 816 RSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFES 875
Query: 415 DKDVKQVTRDYDEEEQGYDSEKEKKE----EKKPIETGSPKTK 453
D + +R S K + P + SP+ K
Sbjct: 876 SPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPK 918
Score = 68.6 bits (166), Expect = 1e-11
Identities = 69/243 (28%), Positives = 111/243 (45%), Gaps = 27/243 (11%)
Query: 208 PSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRH- 266
PS S T + ++ +++ ++ S S+ P + R S S + P S R
Sbjct: 394 PSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREI 453
Query: 267 -----RRSRS-----RSRRRSHSKSRSRRRSKSP---RRRRSHSRERGRRSRSTSKTRDK 313
++RS R + SH+ SR RS+SP +R RS SR +R S S++
Sbjct: 454 SSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQW 513
Query: 314 KKEDKEKK--RSKTPP---KSYSTARRSRSASRERRRR-RSRSGTRSPKKPRSP-KRKLS 366
++ ++ RS++P +S S R S SR +RR RSRS R RSP R S
Sbjct: 514 RRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRS 573
Query: 367 RSPSPRRHKKEKKKDKDKERSRDE---RERSTSKKKKSKDKEKDR---ERKSESDKDVKQ 420
RS +P R + + + + RSR R RS S+ + + + R R+S + V++
Sbjct: 574 RSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRR 633
Query: 421 VTR 423
+R
Sbjct: 634 RSR 636
Score = 65.5 bits (158), Expect = 1e-10
Identities = 82/308 (26%), Positives = 123/308 (39%), Gaps = 37/308 (12%)
Query: 98 TVFVDRALIVVPYAEGVIPDEAKALSLLAPANAVAGLLPGGGLLPTPN-PLTQIGAVPLA 156
+ F D++ ++ V ++ + +A + AG G +P P P + +G P A
Sbjct: 2453 SAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPP-A 2511
Query: 157 ALGAPTLDPALAALGLPGANLNSQSLAADQLLKLMSTVDPKLNHVAAGLVSPSLKSDTSS 216
+ GA ALAAL P S S ++ S+ + ++G S + +
Sbjct: 2512 STGAQQ-PSALAALQ-PAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLP 2569
Query: 217 KEIEEAMKRVREAQSLISAAI------EPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSR 270
+ E A+KRV A+ EP + KRR S S S S + SSS S
Sbjct: 2570 VQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSS 2629
Query: 271 SRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSY 330
S S S S S S S SP + + + K KK ++RS++P K
Sbjct: 2630 SSSSSSSSSSSSSSSSSSSPSPAKPGPQ-------ALPKPASPKKPPPGERRSRSPRKPI 2682
Query: 331 STARRSRSASR---ERRR----------------RRSRSGTR-SPKKPRSPKRKLSRSPS 370
+ R SRS S ERRR R SR G R + P +R+ + SP
Sbjct: 2683 DSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPR 2742
Query: 371 PRRHKKEK 378
P RH+ +
Sbjct: 2743 PMRHRSSR 2750
Score = 65.1 bits (157), Expect = 1e-10
Identities = 69/273 (25%), Positives = 110/273 (40%), Gaps = 53/273 (19%)
Query: 215 SSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRR-RTPSSSR--HRRSRS 271
SS+E++ +K Q + PD K + R R RSRS S SR RRSRS
Sbjct: 1541 SSQELD--VKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRS 1598
Query: 272 RSRRRSHSKSRSRRRSKS----------------PRRRRSHSRERGRRS----------- 304
S K R+ R++S PRR RS S +GR
Sbjct: 1599 GSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESS 1658
Query: 305 -----RSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPK-KP 358
+S + R + + K +S+TPP+ S+ + R RRSRS + SP+ +
Sbjct: 1659 PEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRS 1718
Query: 359 RSPKRKLSRSPS---------PRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRE 409
R+P R RSPS R ++ + + ++ R RS S K + + + R
Sbjct: 1719 RTPPRH-RRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRS 1777
Query: 410 RKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEK 442
R+ ++ + TR D + + ++ +
Sbjct: 1778 RREKT-----RTTRRRDRSGSSQSTSRRRQRSR 1805
Score = 62.0 bits (149), Expect = 1e-09
Identities = 67/299 (22%), Positives = 123/299 (41%), Gaps = 45/299 (15%)
Query: 180 QSLAADQLLKLMSTVDPKLNHVAAGLVSPSLKSDTSSKEIEEAMKRVREAQSLISAAIEP 239
+ +A +L+ L V+P G ++ ++ E+ +R+R A + + ++
Sbjct: 89 EKVATFRLMLLEKDVNPGGKEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDG 148
Query: 240 DKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHS-- 297
+ +RR ++ + P S R S RS + + +++ K R RRS S
Sbjct: 149 SSFDPQRRAREAKQPAPEPPKPYSL----VRESSSSRSPTPKQKKKKKKKDRGRRSESSS 204
Query: 298 --RERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSP 355
RER ++S K R + + K K RS TP +S+ S++++R+RSRS T +P
Sbjct: 205 PRRER-KKSSKKKKHRSESESKKRKHRSPTP--------KSKRKSKDKKRKRSRSTTPAP 255
Query: 356 KKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDR------- 408
K R+ + + S S + + RS + +T+ +S R
Sbjct: 256 KSRRAHRSTSADSAS------SSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAP 309
Query: 409 ---------ERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVE 458
+R S + KQ + Y+ D +K+KKE+ + SP+ E
Sbjct: 310 FSEPGTTSTQRPSSPETATKQPSSPYE------DKDKDKKEKSATRPSPSPERSSTGPE 362
Score = 59.3 bits (142), Expect = 8e-09
Identities = 58/234 (24%), Positives = 90/234 (38%), Gaps = 13/234 (5%)
Query: 234 SAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSR-SRRRSKS--- 289
S++ +K +R SRS S +++ SSR RSRS S RS +KSR S RRS S
Sbjct: 726 SSSERKNKSRTSQRRSRSNSSPEMKKSRISSR--RSRSLSSPRSKAKSRLSLRRSLSGSS 783
Query: 290 --PRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRR 347
P+++ R R S K + + + + S PPK S +S S +
Sbjct: 784 PCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPK 843
Query: 348 SRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTS-----KKKKSK 402
+SGT + + + +S +P+R + + +SR S S + K S
Sbjct: 844 VKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSST 903
Query: 403 DKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECS 456
+ R S VK + G S + + S CS
Sbjct: 904 PPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCS 957
Score = 57.0 bits (136), Expect = 4e-08
Identities = 66/228 (28%), Positives = 93/228 (40%), Gaps = 23/228 (10%)
Query: 247 RHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRS----RRRSKSPRRRRSHSRERGR 302
+ SRS S PS+S RS S S S +K+R+ R RS S S SR R
Sbjct: 1535 QRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPR 1594
Query: 303 RSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRR-RRSRSGTRSPKKPRSP 361
RSRS S E K+K R+ +S S + A R RRSRSG+ S + SP
Sbjct: 1595 RSRSGSSP-----EVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSP 1649
Query: 362 KRKLSRSPSP---------RRHKKEKKKDKDKERSRDERERSTSKKKKS-KDKEKDRERK 411
+ S SP RR + + K K R+ R S S + + K + R R
Sbjct: 1650 EGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRS 1709
Query: 412 SESDKDVKQVTRDYDEEEQGYDS---EKEKKEEKKPIETGSPKTKECS 456
+ S + + T S ++ + ++ SP+TK S
Sbjct: 1710 ASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTS 1757
Score = 55.5 bits (132), Expect = 1e-07
Identities = 53/150 (35%), Positives = 76/150 (50%), Gaps = 26/150 (17%)
Query: 246 RRHSRSRS------RSRRRRTPSSSRHRRSRSR--SRRRSHSKS----RSRRRSKSPR-- 291
RR SRSR+ RSR R +P + R RSR+ +RRRS S++ R R RS++P
Sbjct: 1979 RRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLP 2038
Query: 292 RRRSHSRE-----RGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRR 346
R+RS SR R RSR+ R K+ + + S S++ RSRSA+
Sbjct: 2039 RKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPP--AT 2096
Query: 347 RSRSGTRSPKKPRSPKR-----KLSRSPSP 371
R+ SG+R+P + R + S SP+P
Sbjct: 2097 RNHSGSRTPPVALNSSRMSCFSRPSMSPTP 2126
Score = 51.6 bits (122), Expect = 2e-06
Identities = 56/231 (24%), Positives = 93/231 (40%), Gaps = 20/231 (8%)
Query: 207 SPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRS--------RSRSRRR 258
+P + + S + R + +S +++ E K R SRS +SR R
Sbjct: 717 TPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLR 776
Query: 259 RTPSSSR---HRRSRSRSRRRSHSKSRSRRRSKSP--RRRRSHSRERGRRSRSTSKTRDK 313
R+ S S ++S++ RR S+ + +S++P R R S S ++S++ S+
Sbjct: 777 RSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHS 836
Query: 314 KKEDKEKKRSKTPPKSYS-TARRSRSASRERRRRRSRSGTRSPK-KPRSPKRKLSRSPSP 371
K +S TPP+ S T+ ++ S +RR + P+ K R+P R SP
Sbjct: 837 SSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSP 896
Query: 372 RRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVT 422
R K R R S K K+ + R S +VT
Sbjct: 897 PR-----VKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVT 942
Score = 50.1 bits (118), Expect = 5e-06
Identities = 67/270 (24%), Positives = 98/270 (36%), Gaps = 22/270 (8%)
Query: 212 SDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRR----RTPSSSRHR 267
S+ S +E+A + QS+ S ++ + R S S S + RTPS
Sbjct: 1384 SELSPDAVEKA--GMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRS 1441
Query: 268 RSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPP 327
S R S + SR SP + RS S K + RS++P
Sbjct: 1442 GSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPS 1501
Query: 328 -----KSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKR-----KLSRSPSPRRHKKE 377
T +R RS S +++ + T ++ RS K S SP R
Sbjct: 1502 SPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDS 1561
Query: 378 KKKDKDKERS--RDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSE 435
K K R+ R +S + SK + R +S S +VK R + G DS
Sbjct: 1562 SPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDS- 1620
Query: 436 KEKKEEKKPIETGSP-KTKECSVEKGTGDS 464
E K P P +++ S KG G S
Sbjct: 1621 --SPEPKAPAPRALPRRSRSGSSSKGRGPS 1648
Score = 47.4 bits (111), Expect = 3e-05
Identities = 69/335 (20%), Positives = 118/335 (35%), Gaps = 44/335 (13%)
Query: 144 PNPLTQIGAVPLAALGAPTLDPALAALGLPGANLNSQSLAADQLLKLMSTVDPKLNHVAA 203
P+P +++G P +L P D + + S +DQ L++ P +
Sbjct: 2425 PSPSSRMGQAPSQSLLPPAQDQPRSPV---------PSAFSDQSRCLIAQTTPVAG--SQ 2473
Query: 204 GLVSPSLKSDTSS-----------------KEIEEAMKRVREAQSLISAAIEPDKKEEKR 246
L S ++ + TSS ++ E Q AA++P K+ R
Sbjct: 2474 SLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKE---R 2530
Query: 247 RHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSR--------RRSKSPRRRRSHSR 298
R S S S S + SSS S S S S+ S +R SP +
Sbjct: 2531 RSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAV 2590
Query: 299 ERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRS--PK 356
GR T R ++ S + S S++ S S+S S S + S P
Sbjct: 2591 REGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPS 2650
Query: 357 KPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDK 416
+ + L + SP++ +++ + + D S S ++ + + S D+
Sbjct: 2651 PAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQ 2710
Query: 417 DVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPK 451
R +G + K+ ET SP+
Sbjct: 2711 QSSSSERG---SRRGQRGDSRSPSHKRRRETPSPR 2742
Score = 46.6 bits (109), Expect = 5e-05
Identities = 68/247 (27%), Positives = 93/247 (37%), Gaps = 56/247 (22%)
Query: 178 NSQSLAADQLLKLMSTVDPKLN------HVAAGLVSPSLKSDTSSKEIEEAMKRVREAQS 231
N QS+ + S+ DP+L H +G P +KS T ++ + R Q
Sbjct: 861 NEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQ---SPSRSSSPQP 917
Query: 232 LISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRR--SRSRSR---RRSHSKSRSRRR 286
+ A I P ++ S S SR R TP SR S SR R SHS S S
Sbjct: 918 KVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDT 977
Query: 287 SKSPRR--RRSHS---------RERGRRSRSTSKTRDKKKEDKEKK-------------- 321
P R+SHS + + S S ++ ++K K
Sbjct: 978 KVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCA 1037
Query: 322 --RSKTPP-KSY--------------STARRSRSASRERRRRRSRSGTRSPKKPRSPKRK 364
+S TPP +SY S RS ++S E R+ S S + K SPK
Sbjct: 1038 GVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGG 1097
Query: 365 LSRSPSP 371
SRS SP
Sbjct: 1098 RSRSSSP 1104
Score = 46.2 bits (108), Expect = 7e-05
Identities = 74/346 (21%), Positives = 112/346 (32%), Gaps = 27/346 (7%)
Query: 146 PLTQIGAVPLAALGAPTLDPALAALGLPGANLNSQSLAADQLLKLMSTVDPKLNHVAAGL 205
P+ G+ AAL +L A A L GANL S + ++ P L A
Sbjct: 2349 PVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSR 2408
Query: 206 VSPSLKSDT--SSKEIEEAMKRVREA--QSLISAAIEPDKKEEKRRHSRSRSRSRRRRTP 261
PS S + +S+ R+ +A QSL+ A + + S + TP
Sbjct: 2409 TPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTP 2468
Query: 262 SSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKK 321
+ S + S P HS + G ST + +
Sbjct: 2469 VAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHS-DVGEPPASTGAQQPSALAALQPA 2527
Query: 322 RSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKK-----PRSPKRKLSRSPSPRRHKK 376
+ + S S++ S S+S S SG+ S P P+ L R PSP K
Sbjct: 2528 KERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPK 2587
Query: 377 E-------------KKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTR 423
E K+K + S S+S S S S +
Sbjct: 2588 EAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2647
Query: 424 DYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESK 469
+ G + + KKP P + + DSLR+S+
Sbjct: 2648 SPSPAKPGPQALPKPASPKKP----PPGERRSRSPRKPIDSLRDSR 2689
Score = 31.6 bits (70), Expect = 1.7
Identities = 19/40 (47%), Positives = 23/40 (57%), Gaps = 2/40 (5%)
Query: 234 SAAIEPDKKEEKRRHSRSRSRSRRRRTPS--SSRHRRSRS 271
S++ E + +R SRS S RRR TPS RHR SRS
Sbjct: 2712 SSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSRS 2751
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 94.0 bits (232), Expect = 3e-19
Identities = 58/194 (29%), Positives = 102/194 (52%), Gaps = 14/194 (7%)
Query: 252 RSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTR 311
R R R+R T R R R R R + R R R+R RER R++ +
Sbjct: 3 RQRERKRETDRGKETERERDRQRERENQTERENRH-----RQRDRHRERDRQTDREKERE 57
Query: 312 DKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSP 371
+K+ D++++R + + R R R+R R+R R + R KR+ R+
Sbjct: 58 RQKERDRQRQRERETERE---TERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRE- 113
Query: 372 RRHKKEKKKDKDKERSRD-ERERSTSKKKKSKDKEKDRERKSESDKDVKQ-VTRDYDEEE 429
R K +++DK ER RD ERER ++++ +++++ RERK E+D++ ++ R+ ++E
Sbjct: 114 RNRKGGRERDKQTERERDRERER---QRQRERERQRQRERKRETDRERQRWAEREERKKE 170
Query: 430 QGYDSEKEKKEEKK 443
+ + +KE+KE+KK
Sbjct: 171 RKKERKKERKEKKK 184
Score = 92.4 bits (228), Expect = 8e-19
Identities = 65/209 (31%), Positives = 105/209 (50%), Gaps = 26/209 (12%)
Query: 223 MKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHR-RSRSRSRRRSHSKS 281
M+R RE + E D+ +E R R R R R +T +RHR R R R R R +
Sbjct: 1 MERQRERKR------ETDRGKETERE-RDRQRERENQTERENRHRQRDRHRERDRQTDRE 53
Query: 282 RSRRRSKSPRRRRSHSRERGR---RSRSTSKTRDKKKE-DKEKKRSKTPPKSYSTAR--- 334
+ R R K R+R RE R R R + R++K++ D+E+ + + + T R
Sbjct: 54 KERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRE 113
Query: 335 RSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSR----DE 390
R+R RER ++ R R ++ R +R+ R+ ++E+K++ D+ER R +E
Sbjct: 114 RNRKGGRERDKQTERERDRERERQRQRERE-------RQRQRERKRETDRERQRWAEREE 166
Query: 391 RERSTSKKKKSKDKEKDRERKSESDKDVK 419
R++ K++K + KEK +E K DK K
Sbjct: 167 RKKERKKERKKERKEKKKEEKRREDKKRK 195
Score = 84.0 bits (206), Expect = 3e-16
Identities = 57/197 (28%), Positives = 88/197 (44%), Gaps = 18/197 (9%)
Query: 219 IEEAMKRVREAQSLISAAIEPDKKEEKR----RHSRSRSRSRRRRTPSSSRHRRSRSRSR 274
+E +R RE E D++ E+ R +R R R R R + + R R +
Sbjct: 1 MERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQK 60
Query: 275 RRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRS---------KT 325
R + R R + R+R R+R R+ R T + RDK + D+E+KR K
Sbjct: 61 ERDRQRQRERETERETERQRERQRQRERK-RQTDRERDKDR-DRERKRETDRNRERNRKG 118
Query: 326 PPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKE 385
+ R R RER+R+R R R ++ R R+ R KKE+KK++ KE
Sbjct: 119 GRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKE 178
Query: 386 RS---RDERERSTSKKK 399
R ++E+ R K+K
Sbjct: 179 RKEKKKEEKRREDKKRK 195
Score = 82.0 bits (201), Expect = 1e-15
Identities = 56/210 (26%), Positives = 105/210 (50%), Gaps = 29/210 (13%)
Query: 270 RSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKE-DKEKKRSKTPPK 328
R R R+R + + R + +R R + ER R R + R++ ++ D+EK+R
Sbjct: 3 RQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERE----- 57
Query: 329 SYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSR 388
R R+R+R+R R R ++ R +R+ R R+ +E+ KD+D+ER R
Sbjct: 58 --------RQKERDRQRQRERETERETERQRERQRQRERK---RQTDRERDKDRDRERKR 106
Query: 389 D-ERERSTSKK---------KKSKDKEKDRERKSESDKD-VKQVTRDYDEEEQGYDSEKE 437
+ +R R ++K ++ +D+E++R+R+ E ++ ++ R+ D E Q + +E
Sbjct: 107 ETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREE 166
Query: 438 KKEEKKPIETGSPKTKECSVEKGTGDSLRE 467
+K+E+K K K+ EK D R+
Sbjct: 167 RKKERKKERKKERKEKK-KEEKRREDKKRK 195
Score = 58.2 bits (139), Expect = 2e-08
Identities = 35/142 (24%), Positives = 65/142 (45%), Gaps = 6/142 (4%)
Query: 211 KSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHS---RSRSRSRRRRTPSSSRHR 267
K KE + +R RE + E ++ E++R + R + R R R+ +
Sbjct: 54 KERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRE 113
Query: 268 RSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGR-RSRSTSKTRDK--KKEDKEKKRSK 324
R+R R R R R R + +R+R R+R R R R T + R + ++E+++K+R K
Sbjct: 114 RNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKK 173
Query: 325 TPPKSYSTARRSRSASRERRRR 346
K ++ +++R+
Sbjct: 174 ERKKERKEKKKEEKRREDKKRK 195
Score = 54.7 bits (130), Expect = 2e-07
Identities = 24/102 (23%), Positives = 54/102 (52%)
Query: 342 ERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKS 401
ER+R R R R + R R+ R R + +++D+ +ER R +++K
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
Query: 402 KDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKK 443
+D+++ RER++E + + ++ + E ++ D E++K +++
Sbjct: 62 RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRE 103
Score = 45.8 bits (107), Expect = 9e-05
Identities = 26/111 (23%), Positives = 56/111 (50%), Gaps = 3/111 (2%)
Query: 372 RRHKKEKKKDKDKERSRD---ERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEE 428
R K+E + K+ ER RD ERE T ++ + + +++ RER ++D++ ++ + +
Sbjct: 5 RERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDR 64
Query: 429 EQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDHHEED 479
++ + E E++ E++ + K + + D RE K D + E +
Sbjct: 65 QRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERN 115
>gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial
[Homo sapiens]
Length = 213
Score = 94.0 bits (232), Expect = 3e-19
Identities = 60/207 (28%), Positives = 106/207 (51%), Gaps = 32/207 (15%)
Query: 240 DKKEEKRRHSRSRSRSRRRRTPSSSRH-RRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSR 298
D++ E+RR + R R R + + + RH R R R R R+ + R R R K R R
Sbjct: 18 DRQRERRRET-DRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQR 76
Query: 299 ERGR---RSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSP 355
ER R R R T + RDK++E R RER++++ R R
Sbjct: 77 ERERDRDRQRETERERDKERETD----------------RHTETDRERQKQKEREMERVR 120
Query: 356 KKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRD-ERERSTSKKKKSKDKEKDRERKSES 414
+ R ++++ R +++ ++ D+ER R ERER T +++K++D+ ++RER+ +
Sbjct: 121 DREREKQKEMGR-------ERQTDRETDRERERQAERERETGRERKTEDRHRERERERKR 173
Query: 415 DKDVKQVTRDYDEEEQGYDSEKEKKEE 441
+++ K+ T+ E E+ D E+E++ E
Sbjct: 174 ERERKRETK---ERERHTDMERERQRE 197
Score = 84.0 bits (206), Expect = 3e-16
Identities = 52/205 (25%), Positives = 97/205 (47%), Gaps = 20/205 (9%)
Query: 217 KEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRR 276
+E + R +E+++ + +++ +R R R R R ++T +R R R R R
Sbjct: 25 RETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDR 84
Query: 277 SHSKSRSRRRSKSPRRRRSHSRERGR-RSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARR 335
R R + + R RER + + R + RD+++E K+K+ R
Sbjct: 85 QRETERERDKERETDRHTETDRERQKQKEREMERVRDRERE-KQKEMG-----------R 132
Query: 336 SRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERST 395
R RE R R R R R R+ R ++E+K++++++R ERER T
Sbjct: 133 ERQTDRETDRERERQAERE----RETGRERKTEDRHRERERERKRERERKRETKERERHT 188
Query: 396 S---KKKKSKDKEKDRERKSESDKD 417
++++ D+++DR+R+SE ++D
Sbjct: 189 DMERERQRETDRKRDRQRESERERD 213
Score = 77.4 bits (189), Expect = 3e-14
Identities = 41/182 (22%), Positives = 95/182 (52%), Gaps = 8/182 (4%)
Query: 275 RRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKE-DKEKKRSKTPPKSYSTA 333
R +H+++ + R + RR R+R + S++ + ++ ++ D+E+ R + +
Sbjct: 8 RHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREK- 66
Query: 334 RRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSR-SPSPRRHKKEKKKDKDKERSRDERE 392
+ R R+R R R R R ++ R +R+ R + + R +K+K+++ ++ R R+ +
Sbjct: 67 QTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREK 126
Query: 393 RSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKT 452
+ +++ D+E DRER+ +++++ R+ E + D +E++ E+K +T
Sbjct: 127 QKEMGRERQTDRETDRERERQAERE-----RETGRERKTEDRHRERERERKRERERKRET 181
Query: 453 KE 454
KE
Sbjct: 182 KE 183
Score = 73.6 bits (179), Expect = 4e-13
Identities = 50/198 (25%), Positives = 97/198 (48%), Gaps = 16/198 (8%)
Query: 297 SRERGRRSRSTSKTRDKKKE-----DKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSG 351
S+ GR + + ++T D+++E D+E+ R+K + R R RER R R R
Sbjct: 3 SKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDR 62
Query: 352 TRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKE----KD 407
R + R +R+ R R ++E ++++DKER D + +++K K++E +D
Sbjct: 63 EREKQTDREGERQRERERD-RDRQRETERERDKERETDRHTETDRERQKQKEREMERVRD 121
Query: 408 RERKSESDKD-VKQVTRDYDEE-----EQGYDSEKEKKEEKKPIETGSPKTKECSVEKGT 461
RER+ + + +Q R+ D E E+ ++ +E+K E + E + +E ++ T
Sbjct: 122 REREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRET 181
Query: 462 GDSLRESKVNGDDHHEED 479
+ R + + + E D
Sbjct: 182 KERERHTDMERERQRETD 199
Score = 57.8 bits (138), Expect = 2e-08
Identities = 38/149 (25%), Positives = 61/149 (40%), Gaps = 4/149 (2%)
Query: 215 SSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSR 274
+ +E E +R R+ E DK+ E RH+ + R R+ R R R R
Sbjct: 68 TDREGERQRERERDRDRQRETERERDKERETDRHTET---DRERQKQKEREMERVRDRER 124
Query: 275 RRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTAR 334
+ R R+ + R R ER R + KT D+ +E +E++R + + T
Sbjct: 125 EKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRE-RERERKRERERKRETKE 183
Query: 335 RSRSASRERRRRRSRSGTRSPKKPRSPKR 363
R R ER R+R R ++ +R
Sbjct: 184 RERHTDMERERQRETDRKRDRQRESERER 212
Score = 32.7 bits (73), Expect = 0.76
Identities = 29/117 (24%), Positives = 57/117 (48%), Gaps = 15/117 (12%)
Query: 368 SPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDE 427
S + RH + + D++R ER R T D+E+DR ++S+++ + R D
Sbjct: 3 SKTEGRHTHTETETMDRQR---ERRRET-------DRERDRAKESKTEDRHSERDRQRDR 52
Query: 428 E---EQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDHHEEDMD 481
E E+ D E+EK+ +++ E + ++ ++ T + R+ + D H E D +
Sbjct: 53 ERNRERDRDREREKQTDREG-ERQRERERDRDRQRET-ERERDKERETDRHTETDRE 107
>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
sapiens]
Length = 820
Score = 94.0 bits (232), Expect = 3e-19
Identities = 69/245 (28%), Positives = 119/245 (48%), Gaps = 18/245 (7%)
Query: 239 PDKKEEKRRHS--RSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSH 296
P K+E KR + R R R R R++ S +R RSR RRR S+SRSR RSKS R R H
Sbjct: 15 PSKEERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSAERERRH 74
Query: 297 -----SRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSG 351
+ER R + + +D + DK++KRS P + + ++R ++
Sbjct: 75 KERERDKERDRNKKDRDRDKDGHRRDKDRKRSSLSP----GRGKDFKSRKDRDSKKDEED 130
Query: 352 TRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERK 411
KKP++ L + ++ +E+ + K K S+ ERE K+++ + +E R+R
Sbjct: 131 EHGDKKPKAQPLSLEELLA-KKKAEEEAEAKPKFLSKAEREAEALKRRQQEVEE--RQRM 187
Query: 412 SESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVN 471
E ++ ++ +D + E+E++E ++ +E +T E+G +RE K
Sbjct: 188 LEEERKKRKQFQDLGRKMLEDPQERERRERRERMER---ETNGNEDEEGR-QKIREEKDK 243
Query: 472 GDDHH 476
+ H
Sbjct: 244 SKELH 248
Score = 76.6 bits (187), Expect = 5e-14
Identities = 50/141 (35%), Positives = 77/141 (54%), Gaps = 11/141 (7%)
Query: 309 KTRDKKKEDKEKKRSKTPPKSYSTAR-RSRSASRERRRRRSRSGTRSPKKPRSPKRKLSR 367
K RD +E+KRS+TP + R R S S++R+R RSR R + RS SR
Sbjct: 9 KDRDASPSKEERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSR----SR 64
Query: 368 SPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSES---DKDVKQVTRD 424
S S R ++ K++++DKER R++++R K +DK DR+R S S KD K +D
Sbjct: 65 SKSAERERRHKERERDKERDRNKKDRDRDKDGHRRDK--DRKRSSLSPGRGKDFKS-RKD 121
Query: 425 YDEEEQGYDSEKEKKEEKKPI 445
D ++ D +KK + +P+
Sbjct: 122 RDSKKDEEDEHGDKKPKAQPL 142
Score = 70.9 bits (172), Expect = 3e-12
Identities = 62/248 (25%), Positives = 115/248 (46%), Gaps = 18/248 (7%)
Query: 207 SPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRH-SRSRSRSRRRRTPSSSR 265
SPS + S+ + R R+ +S S + + ++RR SRSRSRSR + R
Sbjct: 14 SPSKEERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSAERERR 73
Query: 266 HRRSRSRSRRRSHSK-----SRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEK 320
H+ R R + R +K + R R+R S S RG+ +S K RD KK+++++
Sbjct: 74 HKE-RERDKERDRNKKDRDRDKDGHRRDKDRKRSSLSPGRGKDFKS-RKDRDSKKDEEDE 131
Query: 321 KRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPR-SPKRKLSRSPSPRRHKKEKK 379
K P +++ S E + ++ + KP+ K + RR ++ ++
Sbjct: 132 HGDKKP--------KAQPLSLEELLAKKKAEEEAEAKPKFLSKAEREAEALKRRQQEVEE 183
Query: 380 KDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEE-EQGYDSEKEK 438
+ + E R +R++ +K + ++RER+ ++ ++ + DEE Q EK+K
Sbjct: 184 RQRMLEEERKKRKQFQDLGRKMLEDPQERERRERRERMERETNGNEDEEGRQKIREEKDK 243
Query: 439 KEEKKPIE 446
+E I+
Sbjct: 244 SKELHAIK 251
Score = 64.7 bits (156), Expect = 2e-10
Identities = 47/159 (29%), Positives = 79/159 (49%), Gaps = 14/159 (8%)
Query: 292 RRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTAR-RSRSASRERRRRRSRS 350
R S S+E +RSR+ + RD+ D+++K S + + +R R R SR R R RS+S
Sbjct: 11 RDASPSKEERKRSRTPDRERDR---DRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKS 67
Query: 351 GTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRER 410
R + ++ R R+KK++ +DKD R +R+RS+ + KD + ++R
Sbjct: 68 AERERR-----HKERERDKERDRNKKDRDRDKDGHRRDKDRKRSSLSPGRGKDFKSRKDR 122
Query: 411 KSESDK-----DVKQVTRDYDEEEQGYDSEKEKKEEKKP 444
S+ D+ D K + EE + E++ E KP
Sbjct: 123 DSKKDEEDEHGDKKPKAQPLSLEELLAKKKAEEEAEAKP 161
Score = 50.8 bits (120), Expect = 3e-06
Identities = 39/145 (26%), Positives = 60/145 (41%), Gaps = 25/145 (17%)
Query: 335 RSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERS 394
R S S+E R+R +R+P + R R SPS KD+ + RSRD R
Sbjct: 11 RDASPSKEERKR-----SRTPDRERDRDRDRKSSPS---------KDRKRHRSRDRRRGG 56
Query: 395 TSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKE 454
+ + +S+ K +RER+ + R+ D+E D K+ ++ K K
Sbjct: 57 SRSRSRSRSKSAERERRHKE--------RERDKER---DRNKKDRDRDKDGHRRDKDRKR 105
Query: 455 CSVEKGTGDSLRESKVNGDDHHEED 479
S+ G G + K EED
Sbjct: 106 SSLSPGRGKDFKSRKDRDSKKDEED 130
>gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo
sapiens]
Length = 375
Score = 92.8 bits (229), Expect = 6e-19
Identities = 66/176 (37%), Positives = 93/176 (52%), Gaps = 20/176 (11%)
Query: 238 EPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHS 297
E K ++R+ SR RS SR R SR RR RSRSR R S+SRSR R KS RS S
Sbjct: 50 EDRHKRKERKSSRGRSHSRSR-----SRERRHRSRSRERKKSRSRSRERKKS----RSRS 100
Query: 298 RERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKK 357
RER ++SRS S+ R ++ + + RS+ R R+ SR R R RSR + +K
Sbjct: 101 RER-KKSRSRSRERKRRIRSRSRSRSR---------HRHRTRSRSRTRSRSRDRKKRIEK 150
Query: 358 PRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSE 413
PR R LSR+PSP + + D + + R K ++ ++KE ++K +
Sbjct: 151 PRRFSRSLSRTPSPPPF-RGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQ 205
Score = 84.0 bits (206), Expect = 3e-16
Identities = 47/145 (32%), Positives = 83/145 (57%), Gaps = 7/145 (4%)
Query: 275 RRSHSKSRSRRRSKSPRRR-RSHSRERGRRSRSTSKTRDKKKEDKEKK--RSKTPPKSYS 331
RR SK +S ++ KS + HS ++GR ++S+ + + + KE+K R ++ +S S
Sbjct: 12 RRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRS 71
Query: 332 TARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDER 391
RR RS SRER++ RSRS R + RS +RK SRS R ++ K++ + + RSR
Sbjct: 72 RERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRS----RSRERKRRIRSRSRSRSRH 127
Query: 392 ERSTSKKKKSKDKEKDRERKSESDK 416
T + +++ + +DR+++ E +
Sbjct: 128 RHRTRSRSRTRSRSRDRKKRIEKPR 152
Score = 81.6 bits (200), Expect = 1e-15
Identities = 64/208 (30%), Positives = 105/208 (50%), Gaps = 19/208 (9%)
Query: 243 EEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHS----KSRSRRRSKSPRRRRSHSR 298
++ RRH S++ ++ + S + R R +S + R +R+ + R RSHSR
Sbjct: 9 KQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR 68
Query: 299 ERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTAR---RSRSASRERRRR-RSRSGTRS 354
R R R S++R++KK + RS+ KS S +R +SRS SRER+RR RSRS +RS
Sbjct: 69 SRSRERRHRSRSRERKKS---RSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRS 125
Query: 355 PKKPRSPKRKLSRSPSPRRHKK-EKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSE 413
+ R+ R +RS S R K+ EK + + SR + + D ++ R+ E
Sbjct: 126 RHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLE 185
Query: 414 SDKDVKQVTRDYDEEEQGYDSEKEKKEE 441
K ++ E+ + EK+K++E
Sbjct: 186 RAKKLQ-------EQREKEMVEKQKQQE 206
Score = 72.0 bits (175), Expect = 1e-12
Identities = 59/184 (32%), Positives = 89/184 (48%), Gaps = 30/184 (16%)
Query: 215 SSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSR 274
SS+ E+ KR +E +S + + E+R SRSR R + R + RSRSR R
Sbjct: 45 SSENGEDRHKR-KERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRER 103
Query: 275 RRSHSKSRSR-RRSKSPRRRRSHSRERGR-RSRSTSKTRDKKKEDKEKKRSKTPPKSYST 332
++S S+SR R RR +S R RS R R R RSR+ S++RD+KK
Sbjct: 104 KKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKR---------------- 147
Query: 333 ARRSRSASRERRRRRSRSGTRSPKKPRSPKRKL---SRSPSPRRHKKEKKKDKDKERSRD 389
E+ RR SRS +R+P P R ++ RR ++ KK + +E+
Sbjct: 148 --------IEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMV 199
Query: 390 ERER 393
E+++
Sbjct: 200 EKQK 203
Score = 50.1 bits (118), Expect = 5e-06
Identities = 40/123 (32%), Positives = 62/123 (50%), Gaps = 13/123 (10%)
Query: 211 KSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSR 270
KS + S+E +++ R RE + S + E +K R SRSRSR R R S RSR
Sbjct: 85 KSRSRSRERKKSRSRSRERKKSRSRSRE--RKRRIRSRSRSRSRHRHRTRSRSRTRSRSR 142
Query: 271 SRSRR----RSHSKSRSRRRSKSPRRRRSHSRE-------RGRRSRSTSKTRDKKKEDKE 319
R +R R S+S SR S P R R+ + + R R++ + R+K+ +K+
Sbjct: 143 DRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQ 202
Query: 320 KKR 322
K++
Sbjct: 203 KQQ 205
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 91.3 bits (225), Expect = 2e-18
Identities = 86/312 (27%), Positives = 143/312 (45%), Gaps = 55/312 (17%)
Query: 210 LKSDTSS----KEIEEAMKRVREAQSLISAAIE--PDKKEEKRRH-----SRSRSRSRRR 258
+K D S KE + + RV+E + + P++K EK + S S+ R RR
Sbjct: 381 IKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRR 440
Query: 259 RTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRD----KK 314
+ +++ ++ + R +S S+S+S+ +SKS R H+R +R RS SK RD K+
Sbjct: 441 NSEKDDKYK-NKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKE 499
Query: 315 KE--------DKEKKRSKTP-------------PKSYSTARRSRSASRE----------- 342
KE D+E+ RSK KS RR++S SRE
Sbjct: 500 KEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYN 559
Query: 343 -RRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKS 401
R R RSRS RS ++ RS RS S H+ +++ + + RSR R+ + +S
Sbjct: 560 SRTRERSRSRDRS-RRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRS 618
Query: 402 KDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGT 461
KD+ + R R S S + + +R+ D+ Y +++ K +K + S + +
Sbjct: 619 KDRRR-RRRDSRSSEREESQSRNKDK----YRNQESKSSHRKENSESEKRMYSKSRDHNS 673
Query: 462 GDSLRESKVNGD 473
++ RE K + D
Sbjct: 674 SNNSREKKADRD 685
Score = 89.4 bits (220), Expect = 7e-18
Identities = 68/286 (23%), Positives = 124/286 (43%), Gaps = 33/286 (11%)
Query: 213 DTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSS-SRHRRSRS 271
D S E ++R E ++ K + R S+ +S+S+ R + + + +R RS
Sbjct: 428 DHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRS 487
Query: 272 RSRRRSHSKSRSRRR---SKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPK 328
RS+ R H + + + SK + RS S+E+ ++ S S D K ++ +R+++ +
Sbjct: 488 RSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSR 547
Query: 329 ---------SYSTARRSRSASRERRRR-RSRSGTRS---------------PKKPRSPKR 363
SY++ R RS SR+R RR RSR+ R ++ RS R
Sbjct: 548 ECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSR 607
Query: 364 KLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTR 423
+ P R K +++ +D S E +S +K K + K RK S+ + + ++
Sbjct: 608 ERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSK 667
Query: 424 DYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESK 469
D EK+ ++ P K K+ S + S+ ++K
Sbjct: 668 SRDHNSSNNSREKKADRDQSPFS----KIKQSSQDNELKSSMLKNK 709
Score = 89.0 bits (219), Expect = 9e-18
Identities = 77/264 (29%), Positives = 125/264 (47%), Gaps = 36/264 (13%)
Query: 211 KSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSR 270
+SD+ K+ E + + + Q L S + E D + K + R++SRSR SR
Sbjct: 503 QSDSKGKDQERSRSKEKSKQ-LESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSR 561
Query: 271 SRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRS---KTPP 327
+R R SRSR RS+ R R+H R+R RS+ + R+++ + + RS +TPP
Sbjct: 562 TRER------SRSRDRSRRV-RSRTHDRDRS-RSKEYHRYREQEYRRRGRSRSRERRTPP 613
Query: 328 KSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDK--E 385
RSRS R RRRR SRS R + R+ K K S H+KE + + +
Sbjct: 614 ------GRSRSKDRRRRRRDSRSSEREESQSRN-KDKYRNQESKSSHRKENSESEKRMYS 666
Query: 386 RSRDERERSTSKKKKS----------KDKEKDRERKS-----ESDKDVKQVTRDYDEEEQ 430
+SRD + S++KK+ K +D E KS + D+ ++ +++ +
Sbjct: 667 KSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSK 726
Query: 431 GYDSEKEKKEEKKPIETGSPKTKE 454
G +++ ++ KK SP T E
Sbjct: 727 GQENDHVHEKNKKFDHESSPGTDE 750
Score = 87.0 bits (214), Expect = 3e-17
Identities = 82/301 (27%), Positives = 143/301 (47%), Gaps = 42/301 (13%)
Query: 206 VSPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSR 265
V KS + SK E++ + R+++ ++ EEKR SRS+ R +
Sbjct: 452 VKKRAKSKSRSKSKEKSKSKERDSKH--------NRNEEKRMRSRSKGRDHEN-VKEKEK 502
Query: 266 HRRSRSRSRRRSHSKSRSRR-RSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSK 324
S+ + + RS SK +S++ SKS S S+E+ RR++S S+ D K K S+
Sbjct: 503 QSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITK-GKHSYNSR 561
Query: 325 TPPKSYSTAR----------RSRSASRE---------RRRRRSRSGTR--SPKKPRSPKR 363
T +S S R R RS S+E RRR RSRS R P + RS R
Sbjct: 562 TRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDR 621
Query: 364 KLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKE----KDRERKSESDKDVK 419
+ R S R ++E+ + ++K++ R++ +S+ +K+ S+ ++ K R+ S ++ K
Sbjct: 622 RRRRRDS-RSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREK 680
Query: 420 QVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDH-HEE 478
+ RD + S ++ + + ++ + SVEK ++SK +DH HE+
Sbjct: 681 KADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKEN----QKSKGQENDHVHEK 736
Query: 479 D 479
+
Sbjct: 737 N 737
Score = 82.8 bits (203), Expect = 6e-16
Identities = 76/264 (28%), Positives = 114/264 (43%), Gaps = 49/264 (18%)
Query: 239 PDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSR 298
P K +EK R +R R R R P+S + S RR ++S + + + PRR R+ SR
Sbjct: 291 PPKADEKERKNRERERERECNPPNS----QPASYQRRLLVTRSGRKIKGRGPRRYRTPSR 346
Query: 299 ERGRRSRSTSKTRDKKKEDKEKKRSKTPP---KSYSTARRSRSASRERRRRRSRS----- 350
R R +RS+TPP + A+R R +S ER + +S
Sbjct: 347 SRSR---------------DRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEI 391
Query: 351 --GTRSPKKPRSPK----RKLSRSPSPRRHKKEKKKD-KDKERSRDERERS--------- 394
RSP + + K R +S SP+ + K++K KD K + RD R S
Sbjct: 392 KENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNK 451
Query: 395 TSKKKKSKDKEKDRERKSESDKDVKQVTRDYDE---EEQGYDSEKEKKEEKKPIETGSPK 451
K+ KSK + K +E+ ++D K + +G D E K++EK+ G +
Sbjct: 452 VKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQ 511
Query: 452 TKECSVEKGTGDSLRESKVNGDDH 475
+ S EK ESK N DH
Sbjct: 512 ERSRSKEK---SKQLESKSNEHDH 532
Score = 82.8 bits (203), Expect = 6e-16
Identities = 68/235 (28%), Positives = 105/235 (44%), Gaps = 27/235 (11%)
Query: 207 SPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSR-RRRTPSSSR 265
S L+S ++ + ++ ++ R AQS K +R RSRSR R R S
Sbjct: 520 SKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRT 579
Query: 266 HRRSRSRSRR---------RSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKE 316
H R RSRS+ R +SRSR R P R RS R R RR +S+ + +
Sbjct: 580 HDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSR 639
Query: 317 DKEKKRSKTPPKSYSTARRSRSASRERRRRRSR-------SGTRSPKKPRSPKRKLSRSP 369
+K+K R++ +S S+ R+ S S +R +SR S + + +SP K+ +S
Sbjct: 640 NKDKYRNQ---ESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSS 696
Query: 370 SPRRHKKEKKKDKDKERSRDERERSTSKKK-------KSKDKEKDRERKSESDKD 417
K K+K+ E+ R E+ K K K+K+ D E +D+D
Sbjct: 697 QDNELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVHEKNKKFDHESSPGTDED 751
Score = 75.9 bits (185), Expect = 8e-14
Identities = 89/329 (27%), Positives = 142/329 (43%), Gaps = 70/329 (21%)
Query: 211 KSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRH-SRSRSRSRRRRTPSSSRHRRS 269
K+D +SK E R+ LI + KKEEK+RH S S S S + SSS + S
Sbjct: 158 KTDAASKPFAEV--RILSCGELIPKS--KVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSS 213
Query: 270 RSRSRRRSHSKSRSRRRSKSPRRR-RSHSRERGRRSRS-TSKTRDKKKEDKEKK------ 321
S S ++ +S++R K R+ R H +E+ +R +S S + + + E+ E +
Sbjct: 214 SDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVR 273
Query: 322 -------------RSKTPPKSYSTARRSRSASRERR-----------RRR---SRSGT-- 352
K+PPK+ R++R RER +RR +RSG
Sbjct: 274 PEEIPPIPENRFLMRKSPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKI 333
Query: 353 --RSPKKPRSPKRKLS-----RSPSPRRHKKEK---------------KKDKDKERSRDE 390
R P++ R+P R S RS +P ++E K DK + E
Sbjct: 334 KGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKE 393
Query: 391 RERSTSKKKKSK-----DKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPI 445
+RS + K+ K + + RK+E +K VK + E + +SEK+ K + K
Sbjct: 394 NQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVK 453
Query: 446 ETGSPKTKECSVEKGTGDSLRESKVNGDD 474
+ K++ S EK R+SK N ++
Sbjct: 454 KRAKSKSRSKSKEKSKSKE-RDSKHNRNE 481
Score = 75.5 bits (184), Expect = 1e-13
Identities = 57/228 (25%), Positives = 101/228 (44%), Gaps = 30/228 (13%)
Query: 246 RRHSRSRSRSRRRRTPSSSRHRRSRSRSRR--------------------RSHSKSRSRR 285
R SRSRSR R RR+ + R+ R++R + + +S R
Sbjct: 342 RTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRV 401
Query: 286 RSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEK--KRSKTPPKSYSTA--RRSRSASR 341
+ + R+ S R++ K +D K KE+ +R+ Y +R++S SR
Sbjct: 402 KERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSR 461
Query: 342 ERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHK--KEKKKDKDKERSRDERERSTSKKK 399
+ + +S+S R K R+ ++++ R H+ KEK+K D + ER RS K K
Sbjct: 462 SKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSK 521
Query: 400 --KSKDKEKDRERKSESDKDVKQVTRDYD--EEEQGYDSEKEKKEEKK 443
+SK E D + E D+ + +R+ D + + Y+S ++ +
Sbjct: 522 QLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSR 569
Score = 67.0 bits (162), Expect = 4e-11
Identities = 67/284 (23%), Positives = 108/284 (38%), Gaps = 22/284 (7%)
Query: 211 KSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSR 270
+S+T +E + R S I+ DK E RS R + + S
Sbjct: 355 RSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSE 414
Query: 271 SRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSY 330
S +R+ K +S S R + E+ + ++ K R K K RSK+ KS
Sbjct: 415 SPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKR-----AKSKSRSKSKEKSK 469
Query: 331 STARRSRSASRERRRRRSRSGTR-----------SPKKPRSPKRKLSRSPSPRRHKKEKK 379
S R S+ E +R RSRS R S K + +R S+ S + K +
Sbjct: 470 SKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNE 529
Query: 380 KDKDKERSRDERERSTSK-----KKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDS 434
D K + +D R +S S+ K K + RER D+ + +R +D ++
Sbjct: 530 HDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHD-RDRSRSK 588
Query: 435 EKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDHHEE 478
E + E++ G +++E G S + D E
Sbjct: 589 EYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSE 632
Score = 37.4 bits (85), Expect = 0.031
Identities = 34/145 (23%), Positives = 64/145 (44%), Gaps = 26/145 (17%)
Query: 339 ASRERRRRRSRSGTRSPKKPRSPKRKLSRS---PSPRRHKKEKKKDK----------DKE 385
+ +E R T + KP + R LS P + K+EKK+ K D +
Sbjct: 146 SGQEVVREIENQKTDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSSSSDSD 205
Query: 386 RSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPI 445
S D + S S +S +EK ++RK + K+ ++ +KEKK+ KK
Sbjct: 206 SSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRK-------------HKKEKKKRKKSK 252
Query: 446 ETGSPKTKECSVEKGTGDSLRESKV 470
++ S +++ ++E ++R ++
Sbjct: 253 KSASSESEAENLEAQPQSTVRPEEI 277
>gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens]
Length = 1007
Score = 90.9 bits (224), Expect = 2e-18
Identities = 83/294 (28%), Positives = 128/294 (43%), Gaps = 50/294 (17%)
Query: 211 KSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSR 270
K + S+ E R + +S I +K + R +S+S +R+ S + R+S+
Sbjct: 181 KKRSKSRSKERTRHRSDKKKSKGGIEIVKEKTTRSKSKERKKSKSPSKRSKSQDQARKSK 240
Query: 271 SRS-RRRSHSK-----------------SRSRRRSKSPRRRRSHSRERGRRSRSTSKTRD 312
S + RRRS K S+S+ R KSP S SR+RG++SRS R
Sbjct: 241 SPTLRRRSQEKIGKARSPTDDKVKIEDKSKSKDRKKSPIINESRSRDRGKKSRSPVDLRG 300
Query: 313 KKKE---------------DKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKK 357
K K+ DKEKK K+P K S+ + +RS S RR RS R
Sbjct: 301 KSKDRRSRSKERKSKRSETDKEKKPIKSPSKDASSGKENRSPS----RRPGRSPKRRSLS 356
Query: 358 PRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKD 417
P+ P+ K RS SP + + K+ K R+ R+ S+ + K +E +R R S
Sbjct: 357 PK-PRDKSRRSRSPLLNDRRSKQSKSPSRTLSPGRRAKSRSLERKRREPERRRLSSPR-- 413
Query: 418 VKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSP--KTKECSVEKGTGDSLRESK 469
TR D+ S +E+ ++ PI SP + + + + LR S+
Sbjct: 414 ----TRPRDD----ILSRRERSKDASPINRWSPTRRRSRSPIRRRSRSPLRRSR 459
Score = 87.0 bits (214), Expect = 3e-17
Identities = 96/363 (26%), Positives = 152/363 (41%), Gaps = 93/363 (25%)
Query: 211 KSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRR------HSRSRSRSRRRRTP--- 261
KS T + +E + + R IE K + R+ SRSR R ++ R+P
Sbjct: 240 KSPTLRRRSQEKIGKARSPTD-DKVKIEDKSKSKDRKKSPIINESRSRDRGKKSRSPVDL 298
Query: 262 -SSSRHRRSRSRSRRRSHSKS-RSRRRSKSP-------RRRRSHSRERGRRSRSTS---K 309
S+ RRSRS+ R+ S++ + ++ KSP + RS SR GR + S K
Sbjct: 299 RGKSKDRRSRSKERKSKRSETDKEKKPIKSPSKDASSGKENRSPSRRPGRSPKRRSLSPK 358
Query: 310 TRDKKKE-------DKEKKRSKTPPKSYSTARRSRSASRERRRR---------------- 346
RDK + D+ K+SK+P ++ S RR++S S ER+RR
Sbjct: 359 PRDKSRRSRSPLLNDRRSKQSKSPSRTLSPGRRAKSRSLERKRREPERRRLSSPRTRPRD 418
Query: 347 -----RSRSGTRSP--------KKPRSPKRKLSRSP-----SPRRHKKEKKKDKDKERSR 388
R RS SP ++ RSP R+ SRSP SPRR + ++ RSR
Sbjct: 419 DILSRRERSKDASPINRWSPTRRRSRSPIRRRSRSPLRRSRSPRRRSRSPRRRDRGRRSR 478
Query: 389 DE-RERSTSK---KKKSKDKEKDR------------ERKSESDKDVKQVTRDYDEEE--- 429
R RS S+ +++S+ K K+ E++S SD +++ + ++EE
Sbjct: 479 SRLRRRSRSRGGRRRRSRSKVKEDKFKGSLSEGMKVEQESSSDDNLEDFDVEEEDEEALI 538
Query: 430 -----------QGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDHHEE 478
Q Y E P E SP++ + D L + ++ E
Sbjct: 539 EQRRIQRQAIVQKYKYLAEDSNMSVPSEPSSPQSSTRTRSPSPDDILERVAADVKEYERE 598
Query: 479 DMD 481
++D
Sbjct: 599 NVD 601
Score = 78.2 bits (191), Expect = 2e-14
Identities = 64/255 (25%), Positives = 113/255 (44%), Gaps = 25/255 (9%)
Query: 225 RVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRR----SRSRSRRRSHSK 280
+V+ LI E +EE H ++R+ +R SS++ + ++ +++RS S+
Sbjct: 128 KVQSGMGLILQGYESGSEEEGEIHEKARNGNRSSTRSSSTKGKLELVDNKITTKKRSKSR 187
Query: 281 SRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSAS 340
S+ R R +S +++ E + TR K KE K+ K KS AR+S+S +
Sbjct: 188 SKERTRHRSDKKKSKGGIEIVKEKT----TRSKSKERKKSKSPSKRSKSQDQARKSKSPT 243
Query: 341 RERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERS------ 394
RRRS+ + P K K+ + KK ++ + R R ++ RS
Sbjct: 244 ---LRRRSQEKIGKARSPTDDKVKIEDKSKSKDRKKSPIINESRSRDRGKKSRSPVDLRG 300
Query: 395 TSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKE 454
SK ++S+ KE+ + ++SE+DK+ K + + G KE + P K
Sbjct: 301 KSKDRRSRSKER-KSKRSETDKEKKPIKSPSKDASSG-------KENRSPSRRPGRSPKR 352
Query: 455 CSVEKGTGDSLRESK 469
S+ D R S+
Sbjct: 353 RSLSPKPRDKSRRSR 367
Score = 60.8 bits (146), Expect = 3e-09
Identities = 65/275 (23%), Positives = 104/275 (37%), Gaps = 57/275 (20%)
Query: 228 EAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRS--RSRSRRRSHSKSRSRR 285
E QSL D EK + + S + SRH++ + RS+ + H S
Sbjct: 5 ETQSLREQPEMEDANSEKSINEENGEVSEDQSQNKHSRHKKKKHKHRSKHKKHKHSSEED 64
Query: 286 RSKSPRRRRSHSRER-----------GRRSRSTSKTRD-KKKEDKEKKRSKTPP------ 327
+ K + + H + + G +K D ED EK+R+
Sbjct: 65 KDKKHKHKHKHKKHKRKEIIDASDKEGMSPAKRTKLDDLALLEDLEKQRALIKAELDNEL 124
Query: 328 -------------KSYSTARRSRSASRERRRRRSRSGTRS----------PKKPRSPKRK 364
+ Y + E+ R +RS TRS K + KR
Sbjct: 125 MEGKVQSGMGLILQGYESGSEEEGEIHEKARNGNRSSTRSSSTKGKLELVDNKITTKKRS 184
Query: 365 LSRSPSPRRHKKEKKKDKD-----KERS----RDERERSTSKKKKSKDKEKDRERKS--- 412
SRS RH+ +KKK K KE++ ER++S S K+SK +++ R+ KS
Sbjct: 185 KSRSKERTRHRSDKKKSKGGIEIVKEKTTRSKSKERKKSKSPSKRSKSQDQARKSKSPTL 244
Query: 413 --ESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPI 445
S + + + D++ + D K K +K PI
Sbjct: 245 RRRSQEKIGKARSPTDDKVKIEDKSKSKDRKKSPI 279
Score = 44.7 bits (104), Expect = 2e-04
Identities = 61/282 (21%), Positives = 102/282 (36%), Gaps = 42/282 (14%)
Query: 208 PSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHR 267
P ++ S K I E V E QS K + + + + RS+ ++ SS
Sbjct: 13 PEMEDANSEKSINEENGEVSEDQS--------QNKHSRHKKKKHKHRSKHKKHKHSSEED 64
Query: 268 RSRSRSRRRSHSKSR-------SRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEK 320
+ + + H K + S + SP +R + K + D E
Sbjct: 65 KDKKHKHKHKHKKHKRKEIIDASDKEGMSPAKRTKLDDLALLEDLEKQRALIKAELDNEL 124
Query: 321 KRSKTPPKSYSTARRSRSASRERRR--RRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEK 378
K + S S E ++R+G RS + S K KL +
Sbjct: 125 MEGKVQSGMGLILQGYESGSEEEGEIHEKARNGNRSSTRSSSTKGKLELVDN-------- 176
Query: 379 KKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDV----KQVTRDYDEEEQGYDS 434
K K+RS K +SK++ + R K +S + ++ TR +E + S
Sbjct: 177 -KITTKKRS----------KSRSKERTRHRSDKKKSKGGIEIVKEKTTRSKSKERKKSKS 225
Query: 435 -EKEKKEEKKPIETGSPKTKECSVEK-GTGDSLRESKVNGDD 474
K K + + ++ SP + S EK G S + KV +D
Sbjct: 226 PSKRSKSQDQARKSKSPTLRRRSQEKIGKARSPTDDKVKIED 267
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 90.5 bits (223), Expect = 3e-18
Identities = 81/296 (27%), Positives = 128/296 (43%), Gaps = 50/296 (16%)
Query: 196 PKLNHVAAGLVSPSLKSDTSSKEIEEAMKR--VREAQSLISAAIEPDKKEEKRRHSRSRS 253
P+L + + PS++ TS+ +I + K + E + +KE+++ RSRS
Sbjct: 221 PELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRS 280
Query: 254 RSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRE----------RGRR 303
RS+ R S +R R R RS S+S S RR SPRRR S R R RR
Sbjct: 281 RSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRR 340
Query: 304 SR------------------STSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRR 345
SR S+S +R + K KR+ +PP+ T R S SAS RRR
Sbjct: 341 SRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPR--KTRRLSPSASPPRRR 398
Query: 346 RRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKK----DKDKERSRDERERSTSKKKKS 401
R P P +P K SP+P++ + +K + + + + T K++
Sbjct: 399 HR-------PSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESP 451
Query: 402 KDKEKDRE---RKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKE 454
K R+ +SE DK K D ++ + Y ++ ++ ++GS + E
Sbjct: 452 SPAPKPRKVELSESEEDKGGKMAAADSVQQRRQY----RRQNQQSSSDSGSSSSSE 503
Score = 75.9 bits (185), Expect = 8e-14
Identities = 69/259 (26%), Positives = 99/259 (38%), Gaps = 52/259 (20%)
Query: 237 IEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRR--- 293
IE +K ++ + + R + SSR +R RSRS RR S+S S RR SP RR
Sbjct: 136 IEQEKLASMKKQDEDKDK-RDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERK 194
Query: 294 RSHSRERGRRSRSTSKTRDKKKEDK----------------------------------- 318
RSHSR R++S S + +K++K
Sbjct: 195 RSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIP 254
Query: 319 EKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPK----KPRSPKRKLSRSPSPRRH 374
E K S + ++ R R R +SRS TRS +PR R SRS SPRR
Sbjct: 255 EPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRR 314
Query: 375 KKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDS 434
+++ + R+ R + ++S+ + R R S S S
Sbjct: 315 PSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLS---------GSSSSSSSS 365
Query: 435 EKEKKEEKKPIETGSPKTK 453
+K P T SP K
Sbjct: 366 RSRSPPKKPPKRTSSPPRK 384
Score = 68.9 bits (167), Expect = 1e-11
Identities = 62/220 (28%), Positives = 99/220 (45%), Gaps = 26/220 (11%)
Query: 217 KEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRS--- 273
+++E + + + +A +++ +R++ +S S S + R +RS ++
Sbjct: 458 RKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEV 517
Query: 274 -RRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKE------KKRSKTP 326
RRR HS SRS S SPR+R+ + RGRR RS S +++ ++R+ TP
Sbjct: 518 GRRRRHSPSRSA--SPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTP 575
Query: 327 P---KSYSTARRSRSASRER-----RRRRSRSGT---RSPKKPRSPKRKLSRSPSPRR-- 373
P ++ S R RS S R +RR S S R+ P PKR+ S SP P+R
Sbjct: 576 PPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRV 635
Query: 374 -HKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKS 412
H K+ R S+ +K S RE +S
Sbjct: 636 SHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARS 675
Score = 67.0 bits (162), Expect = 4e-11
Identities = 79/295 (26%), Positives = 123/295 (41%), Gaps = 60/295 (20%)
Query: 209 SLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRS---RRRRTPSSSR 265
S S +SS +E KR + ++ + +RRHS SRS S R+R+ +S R
Sbjct: 493 SSDSGSSSSSEDERPKR---------SHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPR 543
Query: 266 HRRSRSRS-----RRRSHSKS---RSRRRSKSPRRRRSHSRERGRRSRSTSK-----TRD 312
RR RS S RRRS S + R RR P RRR+ S RRS S + R
Sbjct: 544 GRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRR 603
Query: 313 KKKEDKEKKRSKTPPK----------------SYSTARRSRSASRERRR--------RRS 348
K+R+ +PP S+S + RS+ +RR R+
Sbjct: 604 YSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKG 663
Query: 349 RSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKER----SRDERERSTS-------K 397
S +RS ++ RSP+ SPSPR + R S +R +S S +
Sbjct: 664 SSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRR 723
Query: 398 KKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKT 452
++ + +K ++ S S + V++V+ + K+ P+++ SP T
Sbjct: 724 VSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPST 778
Score = 63.5 bits (153), Expect = 4e-10
Identities = 61/240 (25%), Positives = 106/240 (44%), Gaps = 11/240 (4%)
Query: 215 SSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSR 274
S ++ + ++ +++ S ++ + + KR H ++ RRRR S SR R R
Sbjct: 478 SVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRH-SPSRSASPSPRKR 536
Query: 275 RRSHSKSRSRRRSKS-P--RRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTP-PKSY 330
++ S RRRS S P RRRRS S R R T +++ R ++P P+ Y
Sbjct: 537 QKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRY 596
Query: 331 STARRSRSASRERRRRRSRSGTRSPKKPRS----PKRKLSRSPSPRRHKKEKKKDKDKER 386
S + R + +RR+ S PK+ S PKR++S SP P++ K +
Sbjct: 597 SPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSL 656
Query: 387 SRDERERST-SKKKKSKDKEKDRERKSESDKD-VKQVTRDYDEEEQGYDSEKEKKEEKKP 444
S R+ S+ S+ + + +R S S + Q + +G S ++++ P
Sbjct: 657 SSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSP 716
Score = 63.5 bits (153), Expect = 4e-10
Identities = 66/203 (32%), Positives = 89/203 (43%), Gaps = 28/203 (13%)
Query: 245 KRRHSRSRSRSRR------RRTPS-SSRHRR--SRSRSRRRSHSKSRSRRRSKSPRRRR- 294
KRR S S +R RR+PS SS+HR+ S SRS R + S ++R S SPR R
Sbjct: 632 KRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAP 691
Query: 295 --SHSRERGRRSRSTSKTRDKKKEDKEK-----KRSKTPPKSYSTARRSRSASRERRRRR 347
S S RR S+S R + + R+ P K A S + R R
Sbjct: 692 QTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSR 751
Query: 348 SRSGTRSP---KKPRSPKRKLSRSPS-------PRRHKKEKKKDKDKERSRDERERSTSK 397
S SG+ P K P P S+SPS P + K R+ D+ E K
Sbjct: 752 SVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQ-EGGGKK 810
Query: 398 KKKSKDKEKDRERKSESDKDVKQ 420
KKK KDK+ +++K + K K+
Sbjct: 811 KKKKKDKKHKKDKKHKKHKKHKK 833
Score = 62.4 bits (150), Expect = 9e-10
Identities = 87/332 (26%), Positives = 119/332 (35%), Gaps = 64/332 (19%)
Query: 196 PKLNHVAAGLVSPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRS 255
PK +HV G V + S KR +E P +RR S S +
Sbjct: 507 PKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPP 566
Query: 256 -RRRRTPSSSRHRRSRSRS-RRRSHSKSR--------------------------SRRRS 287
RRRRTP+ RR+ S RRRS S R RR S
Sbjct: 567 PRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRAS 626
Query: 288 KSP--RRRRSHSRERGRRSRSTSKTRDKKKEDKEKK-----------RSKTPPKSYSTAR 334
SP +RR SHS +RS +K R K +K RS P K +S +
Sbjct: 627 PSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSP 686
Query: 335 RSRSASRER-----RRRRSRSGTR--SPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERS 387
R R+ RR S S R SP P R++SR+P P++ KK R
Sbjct: 687 RPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVR- 745
Query: 388 RDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIET 447
R +S + S E ++ V+ + K+ K P T
Sbjct: 746 -----RVSSSRSVSGSPEPAAKKPPAPPSPVQS-----QSPSTNWSPAVPVKKAKSP--T 793
Query: 448 GSPKTKECSVEKGTGDSLRESKVNGDDHHEED 479
SP S ++G G ++ K D H++D
Sbjct: 794 PSPSPPRNSDQEGGGKKKKKKK---DKKHKKD 822
Score = 54.3 bits (129), Expect = 2e-07
Identities = 45/171 (26%), Positives = 74/171 (43%), Gaps = 34/171 (19%)
Query: 299 ERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKP 358
E+ + + + DK K DKE+K S SRE+R R
Sbjct: 137 EQEKLASMKKQDEDKDKRDKEEKES----------------SREKRERS----------- 169
Query: 359 RSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDV 418
RSP+R+ SRSPSPRR ++++ + SR R R+ K +S +++ K+ +
Sbjct: 170 RSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRT---KSRSPSPAPEKKEKTPELPEP 226
Query: 419 KQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESK 469
++ +E S+ K + +PI P+ KE S EK + + K
Sbjct: 227 SVKVKEPSVQEATSTSDILKVPKPEPI----PEPKEPSPEKNSKKEKEKEK 273
Score = 51.6 bits (122), Expect = 2e-06
Identities = 68/290 (23%), Positives = 99/290 (34%), Gaps = 88/290 (30%)
Query: 211 KSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSR 270
KS + ++ + R R S + P ++ RR R R+ RR P RHRRSR
Sbjct: 283 KSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSR 342
Query: 271 SRSRRR----------SHSKSRSRRRS---KSPRRRRSHSRERGRRSRSTSKTRDK---- 313
S RRR S S S SR RS K P+R S R+ R S S S R +
Sbjct: 343 SPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPS 402
Query: 314 --------------------------------------KKEDKEKKRSKTP-PK------ 328
K + EK+ S +P PK
Sbjct: 403 PPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVEL 462
Query: 329 ------------SYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKR------------- 363
+ + ++ R R+ ++ S SG+ S + PKR
Sbjct: 463 SESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRR 522
Query: 364 -KLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKS 412
SRS SP K++K+ R R T +++ R R++
Sbjct: 523 HSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRT 572
Score = 50.1 bits (118), Expect = 5e-06
Identities = 54/175 (30%), Positives = 74/175 (42%), Gaps = 22/175 (12%)
Query: 214 TSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRS-RSRRRRTPSSSRHRRSRSR 272
TS K + RE+ S P K K S S + + S + RR R
Sbjct: 435 TSGKVTKHKGTEKRESPS-------PAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRR 487
Query: 273 SRRRSHSKSRSRRRSKSPRRRRSHSR--ERGRRSRSTSKTRDKKKEDKEKKRSK-TPPKS 329
++S S S S S+ R +RSH + E GRR R + + +KR K T P+
Sbjct: 488 QNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPS---RSASPSPRKRQKETSPR- 543
Query: 330 YSTARRSRSAS-RERRRRRSRSGTRSPKK---PRSPKRKLSRSPSPRRHKKEKKK 380
RR RS S RRRRS S P++ P P R+ + SP PRR ++
Sbjct: 544 ---GRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRR 595
Score = 38.5 bits (88), Expect = 0.014
Identities = 34/128 (26%), Positives = 55/128 (42%), Gaps = 7/128 (5%)
Query: 338 SASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERER-STS 396
SA E ++ + +K S K++ + +KE ++K +ERSR R R S S
Sbjct: 121 SAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREK-RERSRSPRRRKSRS 179
Query: 397 KKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECS 456
+ + RERK + + T+ + EKKE+ + S K KE S
Sbjct: 180 PSPRRRSSPVRRERKRSHSRSPRHRTK-----SRSPSPAPEKKEKTPELPEPSVKVKEPS 234
Query: 457 VEKGTGDS 464
V++ T S
Sbjct: 235 VQEATSTS 242
>gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens]
Length = 344
Score = 88.2 bits (217), Expect = 2e-17
Identities = 75/213 (35%), Positives = 104/213 (48%), Gaps = 14/213 (6%)
Query: 212 SDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSR---SRSRSRRRRTPSSSRHRR 268
+D + E + R + A + D E R+ R + R+ RR+ S SR
Sbjct: 139 ADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGSR--- 195
Query: 269 SRSRSRRRSHSKSR--SRRRSKSPRRRRSHSRERGR-RSRSTSKTRDKKKEDKEKKRSKT 325
SRSRSRRRS S+SR SR RS+S + RS SR R + RSRS SK R + + K K +S
Sbjct: 196 SRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDR 255
Query: 326 PPKSYSTARRSRSASRERRRRRSRSGTRSPKK-PRSPKRKLSRSPSPRRHKKEKKKDKDK 384
S+S RSRS E + RSRS +RSPK+ + + SRS S R K
Sbjct: 256 GSHSHS---RSRSKD-EYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSK 311
Query: 385 ERSRDERERSTSKKKKSKDKEKDRERKSESDKD 417
RS + + + +S+ + K R R S +D
Sbjct: 312 ARSVSPPPKRATSRSRSRSRSKSRSRSRSSSRD 344
Score = 59.3 bits (142), Expect = 8e-09
Identities = 45/143 (31%), Positives = 64/143 (44%), Gaps = 20/143 (13%)
Query: 211 KSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSR 270
KS + S+ + R R + + K ++ HS SRSRS
Sbjct: 221 KSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRS--------------- 265
Query: 271 SRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSY 330
+ + KSRSR RS+SP+ + RSRS S++ K RS +PP
Sbjct: 266 ----KDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKR 321
Query: 331 STARRSRSASRERRRRRSRSGTR 353
+T+ RSRS SR + R RSRS +R
Sbjct: 322 ATS-RSRSRSRSKSRSRSRSSSR 343
Score = 57.0 bits (136), Expect = 4e-08
Identities = 41/132 (31%), Positives = 58/132 (43%), Gaps = 7/132 (5%)
Query: 319 EKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEK 378
E K + +SYS +R SRS SR R R RSR +RS + S R SRS S R +
Sbjct: 180 EDKPRTSHRRSYSGSR-SRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRS 238
Query: 379 KKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEK 438
K K + +S+ + + S+ + KD KS S +R +E G K K
Sbjct: 239 KGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSR------SRSRSPKENGKGDIKSK 292
Query: 439 KEEKKPIETGSP 450
+ + SP
Sbjct: 293 SRSRSQSRSNSP 304
Score = 52.8 bits (125), Expect = 7e-07
Identities = 43/132 (32%), Positives = 60/132 (45%), Gaps = 23/132 (17%)
Query: 328 KSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERS 387
K ++ RRS S SR R R R RS +RS + RS R +S+S S RS
Sbjct: 182 KPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRS---------------RS 226
Query: 388 RDE---RERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKP 444
R R RS SK +KS+ K K K +SD+ +R ++E Y+ + + + P
Sbjct: 227 RSRSKGRSRSRSKGRKSRSKSKS---KPKSDRGSHSHSRSRSKDE--YEKSRSRSRSRSP 281
Query: 445 IETGSPKTKECS 456
E G K S
Sbjct: 282 KENGKGDIKSKS 293
Score = 49.7 bits (117), Expect = 6e-06
Identities = 38/122 (31%), Positives = 60/122 (49%), Gaps = 16/122 (13%)
Query: 211 KSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHR--- 267
+S + S+ + R + +S + +P HSRSRS+ ++ S SR R
Sbjct: 223 RSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPK 282
Query: 268 -------RSRSRSRRRSHSKSR-----SRRRSKSPRRRRSHSRERGR-RSRSTSKTRDKK 314
+S+SRSR +S S S S+ RS SP +R+ SR R R RS+S S++R
Sbjct: 283 ENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSS 342
Query: 315 KE 316
++
Sbjct: 343 RD 344
>gi|38488727 arginine/serine-rich coiled-coil 1 [Homo sapiens]
Length = 334
Score = 86.7 bits (213), Expect = 4e-17
Identities = 60/168 (35%), Positives = 91/168 (54%), Gaps = 14/168 (8%)
Query: 241 KKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKS-PRRRRSHSRE 299
+ + SRS+ + + RR SSS SR+ SR++ KSRS+ RS S + RSHS +
Sbjct: 4 RSSDTEEESRSKRKKKHRRRSSSSSSSDSRTYSRKKGGRKSRSKSRSWSRDLQPRSHSYD 63
Query: 300 RGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPR 359
R RR RS+S + + + + RS+ KSY +RSRS SR RR R +PR
Sbjct: 64 RRRRHRSSSSSSYGSRRKRSRSRSRGRGKSYRV-QRSRSKSRTRRSR---------SRPR 113
Query: 360 SPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKD 407
R SRS H++ + + +D+ER R R++ +K+K K K+K+
Sbjct: 114 L--RSHSRSSERSSHRRTRSRSRDRER-RKGRDKEKREKEKDKGKDKE 158
Score = 81.3 bits (199), Expect = 2e-15
Identities = 78/266 (29%), Positives = 118/266 (44%), Gaps = 44/266 (16%)
Query: 214 TSSKEIEEAMKRVREAQSLISAAIEPDKKEEKR----RHSRSRSRSRRR----RTPSSSR 265
+S E E KR ++ + S++ D + R R SRS+SRS R R+ S R
Sbjct: 5 SSDTEEESRSKRKKKHRRRSSSSSSSDSRTYSRKKGGRKSRSKSRSWSRDLQPRSHSYDR 64
Query: 266 HRRSRSRSR-----RRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEK 320
RR RS S RR S+SRSR R KS R +RS S+ R RRSRS + R + +
Sbjct: 65 RRRHRSSSSSSYGSRRKRSRSRSRGRGKSYRVQRSRSKSRTRRSRSRPRLRSHSRSSER- 123
Query: 321 KRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRK---------------- 364
S+ RR+RS SR+R RR+ R + K+ K K
Sbjct: 124 ----------SSHRRTRSRSRDRERRKGRDKEKREKEKDKGKDKELHNIKRGESGNIKAG 173
Query: 365 LSRSPSPRRHKKEKKKDKDKERSRDE--RERSTSKKKKSKDKEKDRERKSESDKDVKQVT 422
L P + K + + DE + + ++++ + KE+D+ E K VK++
Sbjct: 174 LEHLPPAEQAKARLQLVLEAAAKADEALKAKERNEEEAKRRKEEDQATLVEQVKRVKEIE 233
Query: 423 RDYDEE--EQGYDSEKEKKEEKKPIE 446
+ +Q + S KE K+ +P E
Sbjct: 234 AIESDSFVQQTFRSSKEVKKSVEPSE 259
Score = 68.6 bits (166), Expect = 1e-11
Identities = 51/176 (28%), Positives = 82/176 (46%), Gaps = 16/176 (9%)
Query: 284 RRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTAR----RSRSA 339
RR S + RS +++ RR S+S + D + ++K K+ KS S +R RS S
Sbjct: 3 RRSSDTEEESRSKRKKKHRRRSSSSSSSDSRTYSRKKGGRKSRSKSRSWSRDLQPRSHSY 62
Query: 340 SRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSR-----DERERS 394
R RR R S S + ++ RS R R S R + K + RSR R
Sbjct: 63 DRRRRHRSSSSSSYGSRRKRSRSRSRGRGKSYRVQRSRSKSRTRRSRSRPRLRSHSRSSE 122
Query: 395 TSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKE--KKEEKKPIETG 448
S ++++ + +DRER+ DK+ ++ E+++G D E K+ E I+ G
Sbjct: 123 RSSHRRTRSRSRDRERRKGRDKEKRE-----KEKDKGKDKELHNIKRGESGNIKAG 173
Score = 65.5 bits (158), Expect = 1e-10
Identities = 46/157 (29%), Positives = 79/157 (50%), Gaps = 19/157 (12%)
Query: 301 GRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRS------ 354
GRRS T + K++ K ++RS S S++ SR+ SR++ R+SRS +RS
Sbjct: 2 GRRSSDTEEESRSKRKKKHRRRS-----SSSSSSDSRTYSRKKGGRKSRSKSRSWSRDLQ 56
Query: 355 PKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRD-----ERERSTSKKKKSKDKEKDRE 409
P+ +R+ RS S + +K+ + + R R +R RS S+ ++S+ + + R
Sbjct: 57 PRSHSYDRRRRHRSSSSSSYGSRRKRSRSRSRGRGKSYRVQRSRSKSRTRRSRSRPRLRS 116
Query: 410 RKSESDKDVKQVTRDYD---EEEQGYDSEKEKKEEKK 443
S++ + TR E +G D EK +KE+ K
Sbjct: 117 HSRSSERSSHRRTRSRSRDRERRKGRDKEKREKEKDK 153
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.125 0.342
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,559,865
Number of Sequences: 37866
Number of extensions: 1263597
Number of successful extensions: 64684
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1295
Number of HSP's successfully gapped in prelim test: 1225
Number of HSP's that attempted gapping in prelim test: 17678
Number of HSP's gapped (non-prelim): 18551
length of query: 484
length of database: 18,247,518
effective HSP length: 106
effective length of query: 378
effective length of database: 14,233,722
effective search space: 5380346916
effective search space used: 5380346916
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.