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Search of human proteins with 4758282
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4758282 ephrin receptor EphA7 [Homo sapiens]
(998 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4758282 ephrin receptor EphA7 [Homo sapiens] 2045 0.0
gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sap... 1327 0.0
gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sap... 1313 0.0
gi|4758280 ephrin receptor EphA4 [Homo sapiens] 1302 0.0
gi|21361241 ephrin receptor EphA3 isoform a precursor [Homo sapi... 1286 0.0
gi|145312251 EPH receptor A6 isoform a [Homo sapiens] 1219 0.0
gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo sapi... 1189 0.0
gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo sapi... 1165 0.0
gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo sap... 1162 0.0
gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens] 1136 0.0
gi|150456460 EPH receptor A10 isofom 3 [Homo sapiens] 1078 0.0
gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens] 1076 0.0
gi|32967311 ephrin receptor EphA2 [Homo sapiens] 993 0.0
gi|32528301 EPH receptor B4 precursor [Homo sapiens] 942 0.0
gi|221316650 ephrin receptor EphA1 [Homo sapiens] 808 0.0
gi|194097332 ephrin receptor EphB6 precursor [Homo sapiens] 785 0.0
gi|32967314 ephrin receptor EphA3 isoform b precursor [Homo sapi... 675 0.0
gi|55770892 ephrin receptor EphA8 isoform 2 precursor [Homo sapi... 525 e-149
gi|150456469 EPH receptor A10 isoform 2 [Homo sapiens] 363 e-100
gi|30795229 hemopoietic cell kinase isoform p61HCK [Homo sapiens] 226 1e-58
gi|4557665 insulin-like growth factor 1 receptor precursor [Homo... 222 2e-57
gi|27886593 PTK2 protein tyrosine kinase 2 isoform b [Homo sapiens] 219 1e-56
gi|24476013 PTK2 protein tyrosine kinase 2 isoform a [Homo sapiens] 219 1e-56
gi|4885661 viral oncogene yes-1 homolog 1 [Homo sapiens] 219 1e-56
gi|4503823 protein-tyrosine kinase fyn isoform a [Homo sapiens] 218 2e-56
gi|38202217 proto-oncogene tyrosine-protein kinase SRC [Homo sap... 218 3e-56
gi|4885609 proto-oncogene tyrosine-protein kinase SRC [Homo sapi... 218 3e-56
gi|119395738 insulin receptor isoform Short precursor [Homo sapi... 217 5e-56
gi|119395736 insulin receptor isoform Long precursor [Homo sapiens] 217 5e-56
gi|162287326 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog ... 216 9e-56
>gi|4758282 ephrin receptor EphA7 [Homo sapiens]
Length = 998
Score = 2045 bits (5298), Expect = 0.0
Identities = 998/998 (100%), Positives = 998/998 (100%)
Query: 1 MVFQTRYPSWIILCYIWLLRFAHTGEAQAAKEVLLLDSKAQQTELEWISSPPNGWEEISG 60
MVFQTRYPSWIILCYIWLLRFAHTGEAQAAKEVLLLDSKAQQTELEWISSPPNGWEEISG
Sbjct: 1 MVFQTRYPSWIILCYIWLLRFAHTGEAQAAKEVLLLDSKAQQTELEWISSPPNGWEEISG 60
Query: 61 LDENYTPIRTYQVCQVMEPNQNNWLRTNWISKGNAQRIFVELKFTLRDCNSLPGVLGTCK 120
LDENYTPIRTYQVCQVMEPNQNNWLRTNWISKGNAQRIFVELKFTLRDCNSLPGVLGTCK
Sbjct: 61 LDENYTPIRTYQVCQVMEPNQNNWLRTNWISKGNAQRIFVELKFTLRDCNSLPGVLGTCK 120
Query: 121 ETFNLYYYETDYDTGRNIRENLYVKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSKK 180
ETFNLYYYETDYDTGRNIRENLYVKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSKK
Sbjct: 121 ETFNLYYYETDYDTGRNIRENLYVKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSKK 180
Query: 181 GFYLAFQDVGACIALVSVKVYYKKCWSIIENLAIFPDTVTGSEFSSLVEVRGTCVSSAEE 240
GFYLAFQDVGACIALVSVKVYYKKCWSIIENLAIFPDTVTGSEFSSLVEVRGTCVSSAEE
Sbjct: 181 GFYLAFQDVGACIALVSVKVYYKKCWSIIENLAIFPDTVTGSEFSSLVEVRGTCVSSAEE 240
Query: 241 EAENAPRMHCSAEGEWLVPIGKCICKAGYQQKGDTCEPCGRGFYKSSSQDLQCSRCPTHS 300
EAENAPRMHCSAEGEWLVPIGKCICKAGYQQKGDTCEPCGRGFYKSSSQDLQCSRCPTHS
Sbjct: 241 EAENAPRMHCSAEGEWLVPIGKCICKAGYQQKGDTCEPCGRGFYKSSSQDLQCSRCPTHS 300
Query: 301 FSDKEGSSRCECEDGYYRAPSDPPYVACTRPPSAPQNLIFNINQTTVSLEWSPPADNGGR 360
FSDKEGSSRCECEDGYYRAPSDPPYVACTRPPSAPQNLIFNINQTTVSLEWSPPADNGGR
Sbjct: 301 FSDKEGSSRCECEDGYYRAPSDPPYVACTRPPSAPQNLIFNINQTTVSLEWSPPADNGGR 360
Query: 361 NDVTYRILCKRCSWEQGECVPCGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNG 420
NDVTYRILCKRCSWEQGECVPCGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNG
Sbjct: 361 NDVTYRILCKRCSWEQGECVPCGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNG 420
Query: 421 VSDLSRSQRLFAAVSITTGQAAPSQVSGVMKERVLQRSVELSWQEPEHPNGVITEYEIKY 480
VSDLSRSQRLFAAVSITTGQAAPSQVSGVMKERVLQRSVELSWQEPEHPNGVITEYEIKY
Sbjct: 421 VSDLSRSQRLFAAVSITTGQAAPSQVSGVMKERVLQRSVELSWQEPEHPNGVITEYEIKY 480
Query: 481 YEKDQRERTYSTVKTKSTSASINNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEATG 540
YEKDQRERTYSTVKTKSTSASINNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEATG
Sbjct: 481 YEKDQRERTYSTVKTKSTSASINNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEATG 540
Query: 541 KMFEATAVSSEQNPVIIIAVVAVAGTIILVFMVFGFIIGRRHCGYSKADQEGDEELYFHF 600
KMFEATAVSSEQNPVIIIAVVAVAGTIILVFMVFGFIIGRRHCGYSKADQEGDEELYFHF
Sbjct: 541 KMFEATAVSSEQNPVIIIAVVAVAGTIILVFMVFGFIIGRRHCGYSKADQEGDEELYFHF 600
Query: 601 KFPGTKTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDV 660
KFPGTKTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDV
Sbjct: 601 KFPGTKTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDV 660
Query: 661 AVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALD 720
AVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALD
Sbjct: 661 AVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALD 720
Query: 721 AFLRKHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLS 780
AFLRKHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLS
Sbjct: 721 AFLRKHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLS 780
Query: 781 RVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDM 840
RVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDM
Sbjct: 781 RVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDM 840
Query: 841 SNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPNSL 900
SNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPNSL
Sbjct: 841 SNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPNSL 900
Query: 901 KTPLGTCSRPISPLLDQNTPDFTTFCSVGEWLQAIKMERYKDNFTAAGYNSLESVARMTI 960
KTPLGTCSRPISPLLDQNTPDFTTFCSVGEWLQAIKMERYKDNFTAAGYNSLESVARMTI
Sbjct: 901 KTPLGTCSRPISPLLDQNTPDFTTFCSVGEWLQAIKMERYKDNFTAAGYNSLESVARMTI 960
Query: 961 EDVMSLGITLVGHQKKIMSSIQTMRAQMLHLHGTGIQV 998
EDVMSLGITLVGHQKKIMSSIQTMRAQMLHLHGTGIQV
Sbjct: 961 EDVMSLGITLVGHQKKIMSSIQTMRAQMLHLHGTGIQV 998
>gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sapiens]
Length = 1015
Score = 1327 bits (3434), Expect = 0.0
Identities = 642/990 (64%), Positives = 791/990 (79%), Gaps = 21/990 (2%)
Query: 6 RYPSWIILCYIWLLRFAHTGEAQAAKEVLLLDSKAQQTELEWISSPPNGWEEISGLDENY 65
R P W L LR T A + EV LLDS+ +L WI+ P NGWEEI +DENY
Sbjct: 37 RAPLWTCLLLCAALR---TLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENY 93
Query: 66 TPIRTYQVCQVMEPNQNNWLRTNWISKGNAQRIFVELKFTLRDCNSLPGVLGTCKETFNL 125
PI TYQVC+VME NQNNWL T+WIS A RIF+ELKFTLRDCNSLPG LGTCKETFN+
Sbjct: 94 APIHTYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNM 153
Query: 126 YYYETDYDTGRNIRENLYVKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSKKGFYLA 185
YY+E+D GRNI+EN Y+KIDTIAADESFT+ DLG+R MKLNTEVR++GPLSKKGFYLA
Sbjct: 154 YYFESDDQNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLA 213
Query: 186 FQDVGACIALVSVKVYYKKCWSIIENLAIFPDTVTGSEFSSLVEVRGTCVSSAEEEAENA 245
FQDVGACIALVSV+VYYKKC S++ +LA+FPDT+TG++ S L+EV G+CV+ + +
Sbjct: 214 FQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSV--TDEP 271
Query: 246 PRMHCSAEGEWLVPIGKCICKAGYQQKGDTCEPCGRGFYKSSSQDLQCSRCPTHSFSDKE 305
P+MHCSAEGEWLVPIGKC+CKAGY++K TC+ C GF+K+S C +CP HS++ +E
Sbjct: 272 PKMHCSAEGEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEE 331
Query: 306 GSSRCECEDGYYRAPSDPPYVACTRPPSAPQNLIFNINQTTVSLEWSPPADNGGRNDVTY 365
S+ C CE Y+R SDPP +ACTRPPSAP+N I N+N+T+V LEW PPAD GGR DV+Y
Sbjct: 332 ASTSCVCEKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSY 391
Query: 366 RILCKRCSWEQGECVPCGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLS 425
I CK+C+ G C CG ++ Y+P+Q+GL++ V ++DLLAH NYTFE+EAVNGVSDLS
Sbjct: 392 YIACKKCNSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLS 451
Query: 426 RSQRLFAAVSITTGQAAPSQVSGVMKERVLQRSVELSWQEPEHPNGVITEYEIKYYEKDQ 485
R + +V++TT QAAPS V+ V K ++ + S+ LSWQEP+ PNG+I EYEIKY+EKDQ
Sbjct: 452 PGARQYVSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQ 511
Query: 486 RERTYSTVKTKSTSASINNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEATGKMFEA 545
E +Y+ +K+K T+ + LKP +VYVFQIRA TAAGYG +S R + T
Sbjct: 512 -ETSYTIIKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTP--------V 562
Query: 546 TAVSSEQNPVIIIAVVAVAGTIILVFMVFGFIIGRRHCGYSKADQEGDEE-LYFH---FK 601
A SS+Q+ + +IAV G I+L +V G ++ R CGYSKA Q+ +EE ++FH K
Sbjct: 563 FAASSDQSQIPVIAVSVTVGVILLA-VVIGVLLSGRRCGYSKAKQDPEEEKMHFHNGHIK 621
Query: 602 FPGTKTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVA 661
PG +TYIDP TYEDPN+AVH+FAKE++ASCI IERVIGAGEFGEVCSGRLKLPGKR++
Sbjct: 622 LPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELP 681
Query: 662 VAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDA 721
VAIKTLKVGYTEKQRRDFL EASIMGQFDHPN++HLEGVVT+ KPVMIV E+MENG+LD
Sbjct: 682 VAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDT 741
Query: 722 FLRKHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSR 781
FL+K+DGQFTVIQLVGMLRGI+AGM+YL+DMGYVHRDLAARNIL+NSNLVCKVSDFGLSR
Sbjct: 742 FLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSR 801
Query: 782 VIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMS 841
V+EDDPEA YTT GGKIP+RWTAPEAI +RKFTSASDVWSYGIVMWEV+SYGERPYW+M+
Sbjct: 802 VLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMT 861
Query: 842 NQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPNSLK 901
NQDVIKA+EEGYRLP+PMDCPA L+QLMLDCWQKER RPKF++IV +LDK+IRNP+SLK
Sbjct: 862 NQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLK 921
Query: 902 TPLGTCSRPISPLLDQNTP-DFTTFCSVGEWLQAIKMERYKDNFTAAGYNSLESVARMTI 960
T + R +S LL +++P + SVGEWL+AIKM RY + F GY+S+++VA++T+
Sbjct: 922 TLVNASCR-VSNLLAEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTL 980
Query: 961 EDVMSLGITLVGHQKKIMSSIQTMRAQMLH 990
ED+ LG+TLVGHQKKIM+S+Q M+ Q+++
Sbjct: 981 EDLRRLGVTLVGHQKKIMNSLQEMKVQLVN 1010
>gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sapiens]
Length = 1037
Score = 1313 bits (3397), Expect = 0.0
Identities = 643/1012 (63%), Positives = 792/1012 (78%), Gaps = 43/1012 (4%)
Query: 6 RYPSWIILCYIWLLRFAHTGEAQAAKEVLLLDSKAQQTELEWISSPPNGWEEISGLDENY 65
R P W L LR T A + EV LLDS+ +L WI+ P NGWEEI +DENY
Sbjct: 37 RAPLWTCLLLCAALR---TLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENY 93
Query: 66 TPIRTYQVCQVMEPNQNNWLRTNWISKGNAQRIFVELKFTLRDCNSLPGVLGTCKETFNL 125
PI TYQVC+VME NQNNWL T+WIS A RIF+ELKFTLRDCNSLPG LGTCKETFN+
Sbjct: 94 APIHTYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNM 153
Query: 126 YYYETDYDTGRNIRENLYVKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSKKGFYLA 185
YY+E+D GRNI+EN Y+KIDTIAADESFT+ DLG+R MKLNTEVR++GPLSKKGFYLA
Sbjct: 154 YYFESDDQNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLA 213
Query: 186 FQDVGACIALVSVKVYYKKCWSIIENLAIFPDTVTGSEFSSLVEVRGTCVSSAEEEAENA 245
FQDVGACIALVSV+VYYKKC S++ +LA+FPDT+TG++ S L+EV G+CV+ + +
Sbjct: 214 FQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSV--TDEP 271
Query: 246 PRMHCSAEGEWLVPIGKCICKAGYQQKGDTCEPCGRGFYKSSSQDLQCSRCPTHSFSDKE 305
P+MHCSAEGEWLVPIGKC+CKAGY++K TC+ C GF+K+S C +CP HS++ +E
Sbjct: 272 PKMHCSAEGEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEE 331
Query: 306 GSSRCECEDGYYRAPSDPPYVACTRPPSAPQNLIFNINQTTVSLEWSPPADNGGRNDVTY 365
S+ C CE Y+R SDPP +ACTRPPSAP+N I N+N+T+V LEW PPAD GGR DV+Y
Sbjct: 332 ASTSCVCEKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSY 391
Query: 366 RILCKRCSWEQGECVPCGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLS 425
I CK+C+ G C CG ++ Y+P+Q+GL++ V ++DLLAH NYTFE+EAVNGVSDLS
Sbjct: 392 YIACKKCNSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLS 451
Query: 426 RSQRLFAAVSITTGQAAPSQVSGVMKERVLQRSVELSWQEPEHPNGVITEYEIKYYEKDQ 485
R + +V++TT QAAPS V+ V K ++ + S+ LSWQEP+ PNG+I EYEIKY+EKDQ
Sbjct: 452 PGARQYVSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQ 511
Query: 486 RERTYSTVKTKSTSASINNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEATGKMFEA 545
E +Y+ +K+K T+ + LKP +VYVFQIRA TAAGYG +S R + T
Sbjct: 512 -ETSYTIIKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTP--------V 562
Query: 546 TAVSSEQNPVIIIAVVAVAGTIILVFMVFGFII---------GRR-------------HC 583
A SS+Q+ + +IAV G I+L +V G ++ GR C
Sbjct: 563 FAASSDQSQIPVIAVSVTVGVILLA-VVIGVLLSGSCCECGCGRASSLCAVAHPSLIWRC 621
Query: 584 GYSKADQEGDEE-LYFH---FKFPGTKTYIDPETYEDPNRAVHQFAKELDASCIKIERVI 639
GYSKA Q+ +EE ++FH K PG +TYIDP TYEDPN+AVH+FAKE++ASCI IERVI
Sbjct: 622 GYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVI 681
Query: 640 GAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEG 699
GAGEFGEVCSGRLKLPGKR++ VAIKTLKVGYTEKQRRDFL EASIMGQFDHPN++HLEG
Sbjct: 682 GAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEG 741
Query: 700 VVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDL 759
VVT+ KPVMIV E+MENG+LD FL+K+DGQFTVIQLVGMLRGI+AGM+YL+DMGYVHRDL
Sbjct: 742 VVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDL 801
Query: 760 AARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDV 819
AARNIL+NSNLVCKVSDFGLSRV+EDDPEA YTT GGKIP+RWTAPEAI +RKFTSASDV
Sbjct: 802 AARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDV 861
Query: 820 WSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAE 879
WSYGIVMWEV+SYGERPYW+M+NQDVIKA+EEGYRLP+PMDCPA L+QLMLDCWQKER
Sbjct: 862 WSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNS 921
Query: 880 RPKFEQIVGILDKMIRNPNSLKTPLGTCSRPISPLLDQNTP-DFTTFCSVGEWLQAIKME 938
RPKF++IV +LDK+IRNP+SLKT + R +S LL +++P + SVGEWL+AIKM
Sbjct: 922 RPKFDEIVNMLDKLIRNPSSLKTLVNASCR-VSNLLAEHSPLGSGAYRSVGEWLEAIKMG 980
Query: 939 RYKDNFTAAGYNSLESVARMTIEDVMSLGITLVGHQKKIMSSIQTMRAQMLH 990
RY + F GY+S+++VA++T+ED+ LG+TLVGHQKKIM+S+Q M+ Q+++
Sbjct: 981 RYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQLVN 1032
>gi|4758280 ephrin receptor EphA4 [Homo sapiens]
Length = 986
Score = 1302 bits (3369), Expect = 0.0
Identities = 623/972 (64%), Positives = 775/972 (79%), Gaps = 16/972 (1%)
Query: 30 AKEVLLLDSKAQQTELEWISSP-PNGWEEISGLDENYTPIRTYQVCQVMEPNQNNWLRTN 88
A EV LLDS++ Q EL WI+SP GWEE+S +DE TPIRTYQVC VMEP+QNNWLRT+
Sbjct: 28 ANEVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNTPIRTYQVCNVMEPSQNNWLRTD 87
Query: 89 WISKGNAQRIFVELKFTLRDCNSLPGVLGTCKETFNLYYYETDYDTGRNIRENLYVKIDT 148
WI++ AQR+++E+KFTLRDCNSLPGV+GTCKETFNLYYYE+D D R IREN +VKIDT
Sbjct: 88 WITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESDNDKERFIRENQFVKIDT 147
Query: 149 IAADESFTQGDLGERKMKLNTEVREIGPLSKKGFYLAFQDVGACIALVSVKVYYKKCWSI 208
IAADESFTQ D+G+R MKLNTE+R++GPLSKKGFYLAFQDVGACIALVSV+V+YKKC
Sbjct: 148 IAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKKCPLT 207
Query: 209 IENLAIFPDTVTGSEFSSLVEVRGTCVSSAEEEAENAPRMHCSAEGEWLVPIGKCICKAG 268
+ NLA FPDT+TG++ SSLVEVRG+CV+++EE+ + P+M+C A+GEWLVPIG C+C AG
Sbjct: 208 VRNLAQFPDTITGADTSSLVEVRGSCVNNSEEK--DVPKMYCGADGEWLVPIGNCLCNAG 265
Query: 269 YQQKGDTCEPCGRGFYKSSSQDLQCSRCPTHSFSDKEGSSRCECEDGYYRAPSDPPYVAC 328
++++ C+ C G+YK+ S D C++CP HS+S EG++ C C+ G++RA +D + C
Sbjct: 266 HEERSGECQACKIGYYKALSTDATCAKCPPHSYSVWEGATSCTCDRGFFRADNDAASMPC 325
Query: 329 TRPPSAPQNLIFNINQTTVSLEWSPPADNGGRNDVTYRILCKRC-SWEQGECVPCGSNIG 387
TRPPSAP NLI N+N+T+V+LEWS P + GGR D++Y ++CK+C + + +C PCGS +
Sbjct: 326 TRPPSAPLNLISNVNETSVNLEWSSPQNTGGRQDISYNVVCKKCGAGDPSKCRPCGSGVH 385
Query: 388 YMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFAAVSITTGQAAPSQVS 447
Y PQQ GL+ V++ DLLAH NYTFE+ AVNGVS + + +V++TT QAAPS ++
Sbjct: 386 YTPQQNGLKTTKVSITDLLAHTNYTFEIWAVNGVSKYNPNPDQSVSVTVTTNQAAPSSIA 445
Query: 448 GVMKERVLQRSVELSWQEPEHPNGVITEYEIKYYEKDQRERTYSTVKTKSTSASINNLKP 507
V + V + SV L+W EP+ PNGVI EYE+KYYEKDQ ER+Y V+T + + I L P
Sbjct: 446 LVQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYEKDQNERSYRIVRTAARNTDIKGLNP 505
Query: 508 GTVYVFQIRAFTAAGYGNYSPRLDVATLEEATGKMFEATAVSSEQNPVIIIAVVAVAGTI 567
T YVF +RA TAAGYG++S L+V T + + N +++ V+V+G++
Sbjct: 506 LTSYVFHVRARTAAGYGDFSEPLEVTT------NTVPSRIIGDGANSTVLL--VSVSGSV 557
Query: 568 ILV-FMVFGFIIGRRHCGYSKADQEGDEELYFHFKFPGTKTYIDPETYEDPNRAVHQFAK 626
+LV ++ F+I RR YSKA QE DEE + + G +TY+DP TYEDPN+AV +FAK
Sbjct: 558 VLVVILIAAFVISRRRSKYSKAKQEADEEKHLN---QGVRTYVDPFTYEDPNQAVREFAK 614
Query: 627 ELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCEASIM 686
E+DASCIKIE+VIG GEFGEVCSGRLK+PGKR++ VAIKTLK GYT+KQRRDFL EASIM
Sbjct: 615 EIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLSEASIM 674
Query: 687 GQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGMLRGIAAGM 746
GQFDHPN++HLEGVVT+ KPVMI+ E+MENG+LDAFLRK+DG+FTVIQLVGMLRGI +GM
Sbjct: 675 GQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGM 734
Query: 747 RYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPE 806
+YL+DM YVHRDLAARNILVNSNLVCKVSDFG+SRV+EDDPEA YTT GGKIP+RWTAPE
Sbjct: 735 KYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPE 794
Query: 807 AIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPAPMDCPAGLH 866
AI YRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLP PMDCP LH
Sbjct: 795 AIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPIALH 854
Query: 867 QLMLDCWQKERAERPKFEQIVGILDKMIRNPNSLKTPLGTCSRPISPLLDQNTPDFTTFC 926
QLMLDCWQKER++RPKF QIV +LDK+IRNPNSLK SRP + LLD ++P+F+
Sbjct: 855 QLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGTESSRPNTALLDPSSPEFSAVV 914
Query: 927 SVGEWLQAIKMERYKDNFTAAGYNSLESVARMTIEDVMSLGITLVGHQKKIMSSIQTMRA 986
SVG+WLQAIKM+RYKDNFTAAGY +LE+V + ED+ +GIT + HQ KI+SS+Q MR
Sbjct: 915 SVGDWLQAIKMDRYKDNFTAAGYTTLEAVVHVNQEDLARIGITAITHQNKILSSVQAMRT 974
Query: 987 QMLHLHGTGIQV 998
QM +HG + V
Sbjct: 975 QMQQMHGRMVPV 986
>gi|21361241 ephrin receptor EphA3 isoform a precursor [Homo
sapiens]
Length = 983
Score = 1286 bits (3329), Expect = 0.0
Identities = 609/963 (63%), Positives = 769/963 (79%), Gaps = 15/963 (1%)
Query: 28 QAAKEVLLLDSKAQQTELEWISSPPNGWEEISGLDENYTPIRTYQVCQVMEPNQNNWLRT 87
Q + EV LLDSK Q EL WIS P +GWEEISG+DE+YTPIRTYQVC VM+ +QNNWLRT
Sbjct: 25 QPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRT 84
Query: 88 NWISKGNAQRIFVELKFTLRDCNSLPGVLGTCKETFNLYYYETDYDTGRNIRENLYVKID 147
NW+ + +AQ+I+VELKFTLRDCNS+P VLGTCKETFNLYY E+D D G RE+ + KID
Sbjct: 85 NWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVKFREHQFTKID 144
Query: 148 TIAADESFTQGDLGERKMKLNTEVREIGPLSKKGFYLAFQDVGACIALVSVKVYYKKCWS 207
TIAADESFTQ DLG+R +KLNTE+RE+GP++KKGFYLAFQDVGAC+ALVSV+VY+KKC
Sbjct: 145 TIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPF 204
Query: 208 IIENLAIFPDTVTGSEFSSLVEVRGTCVSSAEEEAENAPRMHCSAEGEWLVPIGKCICKA 267
++NLA+FPDTV + SLVEVRG+CV++++EE + PRM+CS EGEWLVPIGKC C A
Sbjct: 205 TVKNLAMFPDTVP-MDSQSLVEVRGSCVNNSKEE--DPPRMYCSTEGEWLVPIGKCSCNA 261
Query: 268 GYQQKGDTCEPCGRGFYKSSSQDLQCSRCPTHSFSDKEGSSRCECEDGYYRAPSDPPYVA 327
GY+++G C+ C GFYK+ +++C++CP HS + ++GS C CE+ Y+RA DPP +A
Sbjct: 262 GYEERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSMA 321
Query: 328 CTRPPSAPQNLIFNINQTTVSLEWSPPADNGGRNDVTYRILCKRCSWEQGECVPCGSNIG 387
CTRPPS+P+N+I NIN+T+V L+WS P D GGR DVT+ I+CK+C W +C PC N+
Sbjct: 322 CTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVR 381
Query: 388 YMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFAAVSITTGQAAPSQVS 447
++P+Q GL + VTV DLLAH NYTFE++AVNGVS+LS R FAAVSITT QAAPS V
Sbjct: 382 FLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVL 441
Query: 448 GVMKERVLQRSVELSWQEPEHPNGVITEYEIKYYEKDQRERTYSTVKTKSTSASINNLKP 507
+ K+R + S+ LSWQEPEHPNG+I +YE+KYYEK ++E +Y+ ++ + T+ +I++LKP
Sbjct: 442 TIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKP 501
Query: 508 GTVYVFQIRAFTAAGYGNYSPRLDVATLEEATGKMFEATAVSSEQNPVIIIAVVAVAGTI 567
T+YVFQIRA TAAGYG S + + T ++ ++S E + V++IA+ A I
Sbjct: 502 DTIYVFQIRARTAAGYGTNSRKFEFETSPDSF-------SISGESSQVVMIAISAAVAII 554
Query: 568 ILVFMVFGFIIGRRHCGYSKADQEGDEELYF---HFKFPGTKTYIDPETYEDPNRAVHQF 624
+L +++ +IGR CGY ++ L+F H K PG +TY+DP TYEDP +AVH+F
Sbjct: 555 LLTVVIY-VLIGR-FCGYKSKHGADEKRLHFGNGHLKLPGLRTYVDPHTYEDPTQAVHEF 612
Query: 625 AKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCEAS 684
AKELDA+ I I++V+GAGEFGEVCSGRLKLP K++++VAIKTLKVGYTEKQRRDFL EAS
Sbjct: 613 AKELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRRDFLGEAS 672
Query: 685 IMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGMLRGIAA 744
IMGQFDHPN++ LEGVVT+ KPVMIV E+MENG+LD+FLRKHD QFTVIQLVGMLRGIA+
Sbjct: 673 IMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIAS 732
Query: 745 GMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTA 804
GM+YL+DMGYVHRDLAARNIL+NSNLVCKVSDFGLSRV+EDDPEA YTT GGKIP+RWT+
Sbjct: 733 GMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTS 792
Query: 805 PEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPAPMDCPAG 864
PEAI YRKFTSASDVWSYGIV+WEVMSYGERPYW+MSNQDVIKA++EGYRLP PMDCPA
Sbjct: 793 PEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRLPPPMDCPAA 852
Query: 865 LHQLMLDCWQKERAERPKFEQIVGILDKMIRNPNSLKTPLGTCSRPISPLLDQNTPDFTT 924
L+QLMLDCWQK+R RPKFEQIV ILDK+IRNP SLK +RP + LLDQ+ D TT
Sbjct: 853 LYQLMLDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKIITSAAARPSNLLLDQSNVDITT 912
Query: 925 FCSVGEWLQAIKMERYKDNFTAAGYNSLESVARMTIEDVMSLGITLVGHQKKIMSSIQTM 984
F + G+WL + K+ FT Y+S +++A+++ +D+ +G+T+VG QKKI+SSI+ +
Sbjct: 913 FRTTGDWLNGVWTAHCKEIFTGVEYSSCDTIAKISTDDMKKVGVTVVGPQKKIISSIKAL 972
Query: 985 RAQ 987
Q
Sbjct: 973 ETQ 975
>gi|145312251 EPH receptor A6 isoform a [Homo sapiens]
Length = 1130
Score = 1219 bits (3154), Expect = 0.0
Identities = 586/1014 (57%), Positives = 746/1014 (73%), Gaps = 58/1014 (5%)
Query: 32 EVLLLDSKAQQTELEWISSPPNGWEEISGLDENYTPIRTYQVCQVMEPNQNNWLRTNWIS 91
+V+LLD+ EL W + P NGW+ I+ +DE+ PI TYQVC VMEPNQNNWLRTNWIS
Sbjct: 128 QVVLLDTTTVLGELGWKTYPLNGWDAITEMDEHNRPIHTYQVCNVMEPNQNNWLRTNWIS 187
Query: 92 KGNAQRIFVELKFTLRDCNSLPGVLGTCKETFNLYYYETDYDTGRNIRENLYVKIDTIAA 151
+ AQ+I+VE+KFTLRDCNS+P VLGTCKETFNL+Y E+D G + N Y KIDTIAA
Sbjct: 188 RDAAQKIYVEMKFTLRDCNSIPWVLGTCKETFNLFYMESDESHGIKFKPNQYTKIDTIAA 247
Query: 152 DESFTQGDLGERKMKLNTEVREIGPLSKKGFYLAFQDVGACIALVSVKVYYKKCWSIIEN 211
DESFTQ DLG+R +KLNTE+RE+GP+ +KGFYLAFQD+GACIALVSV+V+YKKC + N
Sbjct: 248 DESFTQMDLGDRILKLNTEIREVGPIERKGFYLAFQDIGACIALVSVRVFYKKCPFTVRN 307
Query: 212 LAIFPDTVTGSEFSSLVEVRGTCVSSAEEEAENAPRMHCSAEGEWLVPIGKCICKAGYQQ 271
LA+FPDT+ + SSLVEVRG+CV SAEE + P+++C A+G+WLVP+G+CIC GY++
Sbjct: 308 LAMFPDTIPRVDSSSLVEVRGSCVKSAEER--DTPKLYCGADGDWLVPLGRCICSTGYEE 365
Query: 272 KGDTCEPCGRGFYKSSSQDLQCSRCPTHSFSDKEGSSRCECEDGYYRAPSDPPYVACTRP 331
+C C GFYK+ + + +CS+CP HS + E +S C+CE GY+RA DPP +ACTRP
Sbjct: 366 IEGSCHACRPGFYKAFAGNTKCSKCPPHSLTYMEATSVCQCEKGYFRAEKDPPSMACTRP 425
Query: 332 PSAPQNLIFNINQTTVSLEWSPPADNGGRNDVTYRILCKRCSWEQGECVPCGSNIGYMPQ 391
PSAP+N++FNIN+T + LEWSPP+D GGR D+TY ++CK+C + +C CG + ++P+
Sbjct: 426 PSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSVICKKCGLDTSQCEDCGGGLRFIPR 485
Query: 392 QTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFAAVSITTGQAAPSQVSGVMK 451
TGL +N V V+D ++H NYTFE+EA+NGVS+LS S + F A+++TT Q APS + V K
Sbjct: 486 HTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSFSPKPFTAITVTTDQDAPSLIGVVRK 545
Query: 452 ERVLQRSVELSWQEPEHPNGVITEYEIKYYEKDQRERTYSTVKTKSTSASINNLKPGTVY 511
+ Q S+ LSWQ P NG I +YEIKYYEK+ + TYS+ ++K+ S I LKP T Y
Sbjct: 546 DWASQNSIALSWQAPAFSNGAILDYEIKYYEKEHEQLTYSSTRSKAPSVIITGLKPATKY 605
Query: 512 VFQIRAFTAAGYGNYSPRLDVATLEEATGKMFEATAVSSEQNPVIIIAVVAVAGTIILVF 571
VF IR TA GY YS + + T +E + +++EQ +++IA AV G +LV
Sbjct: 606 VFHIRVRTATGYSGYSQKFEFETGDETSD-------MAAEQGQILVIATAAVGGFTLLVI 658
Query: 572 MVFGFIIGRRHCGYSKADQEGDEE-----LYFHFKFPGTKTYIDPETYEDPNRAVHQFAK 626
+ F+I R Y KA + +E+ H +FPG KTYIDP+TYEDP+ AVH+FAK
Sbjct: 659 LTLFFLITGRCQWYIKAKMKSEEKRRNHLQNGHLRFPGIKTYIDPDTYEDPSLAVHEFAK 718
Query: 627 ELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCEASIM 686
E+D S I+IERVIGAGEFGEVCSGRLK PGKR++ VAIKTLK G+ ++QRRDFL EASIM
Sbjct: 719 EIDPSRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRDFLREASIM 778
Query: 687 GQFDHPNVVHLEGVVTR------------------------------------------G 704
GQFDHPN++ LEGVVT+ G
Sbjct: 779 GQFDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIPAG 838
Query: 705 KPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNI 764
+PVMIV+E+MENG+LD+FLRKHDG FTVIQLVGMLRGIA+GM+YL+DMGYVHRDLAARNI
Sbjct: 839 RPVMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNI 898
Query: 765 LVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGI 824
LVNSNLVCKVSDFGLSRV+EDDPEA YTTTGGKIP+RWTAPEAI YRKF+SASD WSYGI
Sbjct: 899 LVNSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDAWSYGI 958
Query: 825 VMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFE 884
VMWEVMSYGERPYW+MSNQDVI +IEEGYRLPAPM CPA LHQLML CWQKER RPKF
Sbjct: 959 VMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKERNHRPKFT 1018
Query: 885 QIVGILDKMIRNPNSLKTPLGTCSRPISPLLDQNTPDFTTFCSVGEWLQAIKMERYKDNF 944
IV LDK+IRNP++L T + + P P++ F +VG+WL +IKM +YK+NF
Sbjct: 1019 DIVSFLDKLIRNPSALHTLVEDIL--VMPESPGEVPEYPLFVTVGDWLDSIKMGQYKNNF 1076
Query: 945 TAAGYNSLESVARMTIEDVMSLGITLVGHQKKIMSSIQTMRAQMLHLHGTGIQV 998
AAG+ + + ++RM+I+D+ +G+ L+GHQ++I+SSIQT+R M+H+ G V
Sbjct: 1077 VAAGFTTFDLISRMSIDDIRRIGVILIGHQRRIVSSIQTLRLHMMHIQEKGFHV 1130
>gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo sapiens]
Length = 1005
Score = 1189 bits (3076), Expect = 0.0
Identities = 577/995 (57%), Positives = 736/995 (73%), Gaps = 38/995 (3%)
Query: 22 AHTGEAQAAKEVLLLDSKAQQTELEWISSPPNGWEEISGLDENYTPIRTYQVCQVMEPNQ 81
A T + A EV LLD+ + W++ P +GW+ I+ +DE++ PI TYQVC VM PNQ
Sbjct: 21 AATCVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTYQVCNVMSPNQ 80
Query: 82 NNWLRTNWISKGNAQRIFVELKFTLRDCNSLPGVLGTCKETFNLYYYETDYDTGRNIREN 141
NNWLRT+W+ + A+R++ E+KFTLRDCNS+PGVLGTCKETFNLYY E+D D G + +E+
Sbjct: 81 NNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESDRDLGASTQES 140
Query: 142 LYVKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSKKGFYLAFQDVGACIALVSVKVY 201
++KIDTIAADESFT DLG R++KLNTEVR +GPLSK+GFYLAFQD+GAC+A++S+++Y
Sbjct: 141 QFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRIY 200
Query: 202 YKKCWSIIENLAIFPDTVTGSEFSSLVEVRGTCVSSAEEEAENAPRMHCSAEGEWLVPIG 261
YKKC +++ NLA F + VTG++ SSLVEVRG CV +EE + P+M+CSAEGEWLVPIG
Sbjct: 201 YKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEER--DTPKMYCSAEGEWLVPIG 258
Query: 262 KCICKAGYQQKGDTCEPCGRGFYKSSSQDLQCSRCPTHSFSDKEGSSRCECEDGYYRAPS 321
KC+C AGY+++ D C C GFYKS+ D C+RCP HS S + C C+ YYRA
Sbjct: 259 KCVCSAGYEERRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYYRAAL 318
Query: 322 DPPYVACTRPPSAPQNLIFNINQTTVSLEWSPPADNGGRNDVTYRILCKRCSWEQGECVP 381
DPP ACTRPPSAP NLI ++N T+V+LEW+PP D GGR+D+TY +C+RC W C
Sbjct: 319 DPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCPWALSRCEA 378
Query: 382 CGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFAAVSITTGQA 441
CGS ++PQQT L + V +LLAH NY+F +EAVNGVSDLS R A V+ITT QA
Sbjct: 379 CGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAVVNITTNQA 438
Query: 442 APSQVSGVMKERVLQRSVELSWQEPEHPNGVITEYEIKYYEKDQRERTYSTVKTKSTSAS 501
APSQV + +ER Q SV L WQEPE PNG+I EYEIKYYEKD+ ++YST+K +T A+
Sbjct: 439 APSQVVVIRQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEKDKEMQSYSTLKAVTTRAT 498
Query: 502 INNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEATGKMFEATAVSSEQNPVIIIAVV 561
++ LKPGT YVFQ+RA T+AG G +S ++V T GK + ++ I +
Sbjct: 499 VSGLKPGTRYVFQVRARTSAGCGRFSQAMEVET-----GK----PRPRYDTRTIVWICLT 549
Query: 562 AVAGTIILVFMVFGFIIGRRHCGYSKADQEGDEE--------------LYFHF---KFPG 604
+ G ++L+ ++ I +RHCGYSKA Q+ DEE L H K P
Sbjct: 550 LITGLVVLLLLL---ICKKRHCGYSKAFQDSDEEKMHYQNGQAPPPVFLPLHHPPGKLPE 606
Query: 605 TKTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAI 664
+ Y +P TYE+P RA F +E++AS I IE++IG+G+ GEVC GRL++PG+RDV VAI
Sbjct: 607 PQFYAEPHTYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAI 666
Query: 665 KTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLR 724
K LK GYTE+QRRDFL EASIMGQFDHPN++ LEGVVTRG+ MIV E+MENG+LD FLR
Sbjct: 667 KALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLR 726
Query: 725 KHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIE 784
HDGQFT++QLVGMLRG+ AGMRYL+D+GYVHRDLAARN+LV+SNLVCKVSDFGLSRV+E
Sbjct: 727 THDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLE 786
Query: 785 DDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQD 844
DDP+A YTTTGGKIP+RWTAPEAI +R F+SASDVWS+G+VMWEV++YGERPYW+M+N+D
Sbjct: 787 DDPDAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRD 846
Query: 845 VIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPNSLKTPL 904
VI ++EEGYRLPAPM CP LHQLMLDCW K+RA+RP+F QIV +LD +IR+P SL+
Sbjct: 847 VISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPESLRA-T 905
Query: 905 GTCSRPISPLLDQNTPDFT------TFCSVGEWLQAIKMERYKDNFTAAGYNSLESVARM 958
T SR P ++ D +VG+WL +I+M RY+D+F A GY+SL V RM
Sbjct: 906 ATVSRCPPPAFVRSCFDLRGGSGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLRM 965
Query: 959 TIEDVMSLGITLVGHQKKIMSSIQTMRAQMLHLHG 993
+DV +LGITL+GHQKKI+ SIQTMRAQ+ G
Sbjct: 966 NAQDVRALGITLMGHQKKILGSIQTMRAQLTSTQG 1000
>gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo
sapiens]
Length = 987
Score = 1165 bits (3015), Expect = 0.0
Identities = 572/971 (58%), Positives = 727/971 (74%), Gaps = 19/971 (1%)
Query: 29 AAKEVLLLDSKAQQTELEWISSPPNGWEEISGLDENYTPIRTYQVCQVMEPNQNNWLRTN 88
AA E L+DS EL W+ PP+GWEE+SG DEN IRTYQVC V E +QNNWLRT
Sbjct: 17 AAVEETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQVCNVFESSQNNWLRTK 76
Query: 89 WISKGNAQRIFVELKFTLRDCNSLPGVLGTCKETFNLYYYETDYDTGR----NIRENLYV 144
+I + A RI VE+KF++RDC+S+P V G+CKETFNLYYYE D+D+ N EN +V
Sbjct: 77 FIRRRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDSATKTFPNWMENPWV 136
Query: 145 KIDTIAADESFTQGDLGERKMKLNTEVREIGPLSKKGFYLAFQDVGACIALVSVKVYYKK 204
K+DTIAADESF+Q DLG R MK+NTEVR GP+S+ GFYLAFQD G C++L++V+V+Y+K
Sbjct: 137 KVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYGGCMSLIAVRVFYRK 196
Query: 205 CWSIIENLAIFPDTVTGSEFSSLVEVRGTCVSSAEEEAENAPRMHCSAEGEWLVPIGKCI 264
C II+N AIF +T++G+E +SLV RG+C+++AEE + +++C+ +GEWLVPIG+C+
Sbjct: 197 CPRIIQNGAIFQETLSGAESTSLVAARGSCIANAEE-VDVPIKLYCNGDGEWLVPIGRCM 255
Query: 265 CKAGYQ--QKGDTCEPCGRGFYKSSSQDLQCSRCPTHSFSDKEGSSRCECEDGYYRAPSD 322
CKAG++ + G C C G +K++ D C+ CP +S + EG++ C C +GYYRA D
Sbjct: 256 CKAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNCVCRNGYYRADLD 315
Query: 323 PPYVACTRPPSAPQNLIFNINQTTVSLEWSPPADNGGRNDVTYRILCKRCSWEQGECVPC 382
P + CT PSAPQ +I ++N+T++ LEW+PP D+GGR D+ Y I+CK C +G C C
Sbjct: 316 PLDMPCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICKSCGSGRGACTRC 375
Query: 383 GSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFAAVSITTGQAA 442
G N+ Y P+Q GL + + + DLLAH YTFE++AVNGV+D S FA+V+ITT QAA
Sbjct: 376 GDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFASVNITTNQAA 435
Query: 443 PSQVSGVMKERVLQRSVELSWQEPEHPNGVITEYEIKYYEKDQRERTYSTVKTKSTSASI 502
PS VS + + S+ LSW +P+ PNGVI +YE++YYEK+ E + +K+ + + ++
Sbjct: 436 PSAVSIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEYNATAIKSPTNTVTV 495
Query: 503 NNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEATGKMFEATAVSSEQNPVIIIAVVA 562
LK G +YVFQ+RA T AGYG YS ++ T+ EA E E+ P+II + +
Sbjct: 496 QGLKAGAIYVFQVRARTVAGYGRYSGKMYFQTMTEA-----EYQTSIQEKLPLIIGS--S 548
Query: 563 VAGTIILVFMVFGFIIGRRHCGYSKADQEGDEELYFHFK---FPGTKTYIDPETYEDPNR 619
AG + L+ +V I+ R G+ +AD E ++L + PG K YIDP TYEDPN
Sbjct: 549 AAGLVFLIAVVVIAIVCNRRRGFERADSEYTDKLQHYTSGHMTPGMKIYIDPFTYEDPNE 608
Query: 620 AVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDF 679
AV +FAKE+D SC+KIE+VIGAGEFGEVCSG LKLPGKR++ VAIKTLK GYTEKQRRDF
Sbjct: 609 AVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDF 668
Query: 680 LCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGML 739
L EASIMGQFDHPNV+HLEGVVT+ PVMI+ EFMENG+LD+FLR++DGQFTVIQLVGML
Sbjct: 669 LSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGML 728
Query: 740 RGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDD-PEAVYTTT-GGK 797
RGIAAGM+YLADM YVHRDLAARNILVNSNLVCKVSDFGLSR +EDD + YT+ GGK
Sbjct: 729 RGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGK 788
Query: 798 IPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPA 857
IP+RWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDM+NQDVI AIE+ YRLP
Sbjct: 789 IPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPP 848
Query: 858 PMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPNSLKTPLGTCSRPISPLLDQ 917
PMDCP+ LHQLMLDCWQK+R RPKF QIV LDKMIRNPNSLK S PLLD+
Sbjct: 849 PMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLSSGINLPLLDR 908
Query: 918 NTPDFTTFCSVGEWLQAIKMERYKDNFTAAGYNSLESVARMTIEDVMSLGITLVGHQKKI 977
PD+T+F +V EWL+AIKM +YK++F AG+ S + V++M +ED++ +G+TL GHQKKI
Sbjct: 909 TIPDYTSFNTVDEWLEAIKMGQYKESFANAGFTSFDVVSQMMMEDILRVGVTLAGHQKKI 968
Query: 978 MSSIQTMRAQM 988
++SIQ MRAQM
Sbjct: 969 LNSIQVMRAQM 979
>gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo
sapiens]
Length = 986
Score = 1162 bits (3006), Expect = 0.0
Identities = 572/971 (58%), Positives = 727/971 (74%), Gaps = 20/971 (2%)
Query: 29 AAKEVLLLDSKAQQTELEWISSPPNGWEEISGLDENYTPIRTYQVCQVMEPNQNNWLRTN 88
AA E L+DS EL W+ PP+GWEE+SG DEN IRTYQVC V E +QNNWLRT
Sbjct: 17 AAVEETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQVCNVFESSQNNWLRTK 76
Query: 89 WISKGNAQRIFVELKFTLRDCNSLPGVLGTCKETFNLYYYETDYDTGR----NIRENLYV 144
+I + A RI VE+KF++RDC+S+P V G+CKETFNLYYYE D+D+ N EN +V
Sbjct: 77 FIRRRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDSATKTFPNWMENPWV 136
Query: 145 KIDTIAADESFTQGDLGERKMKLNTEVREIGPLSKKGFYLAFQDVGACIALVSVKVYYKK 204
K+DTIAADESF+Q DLG R MK+NTEVR GP+S+ GFYLAFQD G C++L++V+V+Y+K
Sbjct: 137 KVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYGGCMSLIAVRVFYRK 196
Query: 205 CWSIIENLAIFPDTVTGSEFSSLVEVRGTCVSSAEEEAENAPRMHCSAEGEWLVPIGKCI 264
C II+N AIF +T++G+E +SLV RG+C+++AEE + +++C+ +GEWLVPIG+C+
Sbjct: 197 CPRIIQNGAIFQETLSGAESTSLVAARGSCIANAEE-VDVPIKLYCNGDGEWLVPIGRCM 255
Query: 265 CKAGYQ--QKGDTCEPCGRGFYKSSSQDLQCSRCPTHSFSDKEGSSRCECEDGYYRAPSD 322
CKAG++ + G C C G +K++ D C+ CP +S + EG++ C C +GYYRA D
Sbjct: 256 CKAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNCVCRNGYYRADLD 315
Query: 323 PPYVACTRPPSAPQNLIFNINQTTVSLEWSPPADNGGRNDVTYRILCKRCSWEQGECVPC 382
P + CT PSAPQ +I ++N+T++ LEW+PP D+GGR D+ Y I+CK C +G C C
Sbjct: 316 PLDMPCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICKSCGSGRGACTRC 375
Query: 383 GSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFAAVSITTGQAA 442
G N+ Y P+Q GL + + + DLLAH YTFE++AVNGV+D S FA+V+ITT QAA
Sbjct: 376 GDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFASVNITTNQAA 435
Query: 443 PSQVSGVMKERVLQRSVELSWQEPEHPNGVITEYEIKYYEKDQRERTYSTVKTKSTSASI 502
PS VS + + S+ LSW +P+ PNGVI +YE++YYEK+ E + +K+ + + ++
Sbjct: 436 PSAVSIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEYNATAIKSPTNTVTV 495
Query: 503 NNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEATGKMFEATAVSSEQNPVIIIAVVA 562
LK G +YVFQ+RA T AGYG YS ++ T+ EA E E+ P+II + +
Sbjct: 496 QGLKAGAIYVFQVRARTVAGYGRYSGKMYFQTMTEA-----EYQTSIQEKLPLIIGS--S 548
Query: 563 VAGTIILVFMVFGFIIGRRHCGYSKADQEGDEELYFHFK---FPGTKTYIDPETYEDPNR 619
AG + L+ +V I+ R G+ +AD E ++L + PG K YIDP TYEDPN
Sbjct: 549 AAGLVFLIAVVVIAIVCNRR-GFERADSEYTDKLQHYTSGHMTPGMKIYIDPFTYEDPNE 607
Query: 620 AVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDF 679
AV +FAKE+D SC+KIE+VIGAGEFGEVCSG LKLPGKR++ VAIKTLK GYTEKQRRDF
Sbjct: 608 AVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDF 667
Query: 680 LCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGML 739
L EASIMGQFDHPNV+HLEGVVT+ PVMI+ EFMENG+LD+FLR++DGQFTVIQLVGML
Sbjct: 668 LSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGML 727
Query: 740 RGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDD-PEAVYTTT-GGK 797
RGIAAGM+YLADM YVHRDLAARNILVNSNLVCKVSDFGLSR +EDD + YT+ GGK
Sbjct: 728 RGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGK 787
Query: 798 IPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPA 857
IP+RWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDM+NQDVI AIE+ YRLP
Sbjct: 788 IPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPP 847
Query: 858 PMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPNSLKTPLGTCSRPISPLLDQ 917
PMDCP+ LHQLMLDCWQK+R RPKF QIV LDKMIRNPNSLK S PLLD+
Sbjct: 848 PMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLSSGINLPLLDR 907
Query: 918 NTPDFTTFCSVGEWLQAIKMERYKDNFTAAGYNSLESVARMTIEDVMSLGITLVGHQKKI 977
PD+T+F +V EWL+AIKM +YK++F AG+ S + V++M +ED++ +G+TL GHQKKI
Sbjct: 908 TIPDYTSFNTVDEWLEAIKMGQYKESFANAGFTSFDVVSQMMMEDILRVGVTLAGHQKKI 967
Query: 978 MSSIQTMRAQM 988
++SIQ MRAQM
Sbjct: 968 LNSIQVMRAQM 978
>gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens]
Length = 984
Score = 1136 bits (2939), Expect = 0.0
Identities = 567/985 (57%), Positives = 722/985 (73%), Gaps = 20/985 (2%)
Query: 13 LCYIWLLRFAHTGEAQAAKEVLLLDSKAQQTELEWISSPPNGWEEISGLDENYTPIRTYQ 72
L Y+ LL A A AA E L+D++ EL W ++P +GWEE+SG DEN IRTYQ
Sbjct: 3 LDYLLLLLLA---SAVAAMEETLMDTRTATAELGWTANPASGWEEVSGYDENLNTIRTYQ 59
Query: 73 VCQVMEPNQNNWLRTNWISKGNAQRIFVELKFTLRDCNSLPGVLGTCKETFNLYYYETD- 131
VC V EPNQNNWL T +I++ A RI+ E++FT+RDC+SLP V G+CKETFNLYYYETD
Sbjct: 60 VCNVFEPNQNNWLLTTFINRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDS 119
Query: 132 -YDTGRNI--RENLYVKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSKKGFYLAFQD 188
T ++ E Y+K+DTIAADESF+Q D G R MK+NTEVR GPL++ GFYLAFQD
Sbjct: 120 VIATKKSAFWSEAPYLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQD 179
Query: 189 VGACIALVSVKVYYKKCWSIIENLAIFPDTVTGSEFSSLVEVRGTCVSSAEEEAENAPRM 248
GAC++L+SV+V++KKC SI++N A+FP+T+TG+E +SLV RGTC+ +AEE + ++
Sbjct: 180 YGACMSLLSVRVFFKKCPSIVQNFAVFPETMTGAESTSLVIARGTCIPNAEE-VDVPIKL 238
Query: 249 HCSAEGEWLVPIGKCICKAGYQQKGDT-CEPCGRGFYKSSSQDLQCSRCPTHSFSDKEGS 307
+C+ +GEW+VPIG+C CK GY+ + C+ C G +K+S + CS CP++S S E S
Sbjct: 239 YCNGDGEWMVPIGRCTCKPGYEPENSVACKACPAGTFKASQEAEGCSHCPSNSRSPAEAS 298
Query: 308 SRCECEDGYYRAPSDPPYVACTRPPSAPQNLIFNINQTTVSLEWSPPADNGGRNDVTYRI 367
C C GYYRA DPP VACT PS P+N+I +N+T++ LEW PP + GGR+DVTY I
Sbjct: 299 PICTCRTGYYRADFDPPEVACTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNI 358
Query: 368 LCKRCSWEQGECVPCGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRS 427
+CK+C ++ C C N+ ++P+Q GL + V++ L AH YTF+++A+NGVS S
Sbjct: 359 ICKKCRADRRSCSRCDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPF 418
Query: 428 QRLFAAVSITTGQAAPSQVSGVMKERVLQRSVELSWQEPEHPNGVITEYEIKYYEKDQRE 487
+V+ITT QAAPS V + + RS+ LSW +PE PNG+I +YEI+YYEK+ E
Sbjct: 419 PPQHVSVNITTNQAAPSTVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEHNE 478
Query: 488 RTYSTVKTKSTSASINNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEATGKMFEATA 547
S ++++ +A I+ L+PG VYV Q+RA T AGYG +S ++ TL + K
Sbjct: 479 FNSSMARSQTNTARIDGLRPGMVYVVQVRARTVAGYGKFSGKMCFQTLTDDDYK------ 532
Query: 548 VSSEQNPVIIIAVVAVAGTIILVFMVFGFIIGRRHCGYSKADQEGDEELYFHFK--FPGT 605
S + + +IA A AG + +V +V I+ R YSK D+ ++ PG
Sbjct: 533 -SELREQLPLIAGSAAAGVVFVVSLVAISIVCSRKRAYSKEAVYSDKLQHYSTGRGSPGM 591
Query: 606 KTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAIK 665
K YIDP TYEDPN AV +FAKE+D S +KIE VIGAGEFGEV GRLKLPGKR++ VAIK
Sbjct: 592 KIYIDPFTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIK 651
Query: 666 TLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRK 725
TLK GY+EKQRRDFL EASIMGQFDHPN++ LEGVVT+ +PVMI+ EFMENGALD+FLR+
Sbjct: 652 TLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQ 711
Query: 726 HDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIED 785
+DGQFTVIQLVGMLRGIAAGM+YLA+M YVHRDLAARNILVNSNLVCKVSDFGLSR ++D
Sbjct: 712 NDGQFTVIQLVGMLRGIAAGMKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQD 771
Query: 786 D-PEAVYTTT-GGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQ 843
D + YT++ GGKIPVRWTAPEAI YRKFTSASDVWSYGIVMWEVMS+GERPYWDMSNQ
Sbjct: 772 DTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQ 831
Query: 844 DVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPNSLKTP 903
DVI AIE+ YRLP PMDCPA LHQLMLDCWQK+R RP+F +IV LDKMIRNP SLKT
Sbjct: 832 DVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTV 891
Query: 904 LGTCSRPISPLLDQNTPDFTTFCSVGEWLQAIKMERYKDNFTAAGYNSLESVARMTIEDV 963
+ P PLLD++ PDFT F +V +WL AIKM +Y+D+F AG+ SL+ V +MT ED+
Sbjct: 892 ATITAVPSQPLLDRSIPDFTAFTTVDDWLSAIKMVQYRDSFLTAGFTSLQLVTQMTSEDL 951
Query: 964 MSLGITLVGHQKKIMSSIQTMRAQM 988
+ +GITL GHQKKI++SI +MR Q+
Sbjct: 952 LRIGITLAGHQKKILNSIHSMRVQI 976
>gi|150456460 EPH receptor A10 isofom 3 [Homo sapiens]
Length = 1008
Score = 1078 bits (2787), Expect = 0.0
Identities = 531/985 (53%), Positives = 707/985 (71%), Gaps = 25/985 (2%)
Query: 30 AKEVLLLDSKAQQTELEWISSPPNGWEEISGLDENYTPIRTYQVCQVMEPNQNNWLRTNW 89
A+EV+LLDSKA Q EL W + P NGWEEISG+DE+ PIRTYQVC V+EPNQ+NWL+T W
Sbjct: 33 AEEVILLDSKASQAELGWTALPSNGWEEISGVDEHDRPIRTYQVCNVLEPNQDNWLQTGW 92
Query: 90 ISKGNAQRIFVELKFTLRDCNSLPGVLGTCKETFNLYYYETDYDTGRN---IRENLYVKI 146
IS+G QRIFVEL+FTLRDC+S+PG GTCKETFN+YY ET+ D GR + + KI
Sbjct: 93 ISRGRGQRIFVELQFTLRDCSSIPGAAGTCKETFNVYYLETEADLGRGRPRLGGSRPRKI 152
Query: 147 DTIAADESFTQGDLGERKMKLNTEVREIGPLSKKGFYLAFQDVGACIALVSVKVYYKKCW 206
DTIAADESFTQGDLGERKMKLNTEVREIGPLS++GF+LAFQDVGAC+ALVSV+VYYK+C
Sbjct: 153 DTIAADESFTQGDLGERKMKLNTEVREIGPLSRRGFHLAFQDVGACVALVSVRVYYKQCR 212
Query: 207 SIIENLAIFPDTVTGSEFSSLVEVRGTCVSSAEEEAENAPRMHCSAEGEWLVPIGKCICK 266
+ + LA FP T S FS+LVEV GTCV+ +E E + PRMHC A+GEWLVP+G+C C
Sbjct: 213 ATVRGLATFPATAAESAFSTLVEVAGTCVAHSEGEPGSPPRMHCGADGEWLVPVGRCSCS 272
Query: 267 AGYQQKGDTCEPCGRGFYKSSSQDLQCSRCPTHSFSDKEGSSRCECEDGYYRAPSDPPYV 326
AG+Q++GD CE C GFYK S + CS CP HS + + S+ C C+D Y R+P+DPP
Sbjct: 273 AGFQERGDFCEACPPGFYKVSPRRPLCSPCPEHSRALENASTFCVCQDSYARSPTDPPSA 332
Query: 327 ACTRPPSAPQNLIFNINQT--TVSLEWSPPADNGGRNDVTYRILCKRCSWE--QGECVPC 382
+CTRPPSAP++L ++++++ + L W PPAD+GGR+DVTY +LC RC E G C PC
Sbjct: 333 SCTRPPSAPRDLQYSLSRSPLVLRLRWLPPADSGGRSDVTYSLLCLRCGREGPAGACEPC 392
Query: 383 GSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVS-DLSRSQRLFAAVSITTGQA 441
G + ++P+Q GL + T++ L A YT V A+NGVS + + +A V+++TG
Sbjct: 393 GPRVAFLPRQAGLRERAATLLHLRPGARYTVRVAALNGVSGPAAAAGTTYAQVTVSTGPG 452
Query: 442 APSQVSGVMKERVLQRSVELSWQEP---EHPNGVITEYEIKYYEKDQRERTYSTVKTKST 498
AP + + ++RV +SV LSW+EP P TEYEI+YYEK Q E+TYS VKT +
Sbjct: 453 APWEEDEIRRDRVEPQSVSLSWREPIPAGAPGANDTEYEIRYYEKGQSEQTYSMVKTGAP 512
Query: 499 SASINNLKPGTVYVFQIRAFTAA---GYGNYSPRLDVATLEEATGKMFEATAVSSEQNPV 555
+ ++ NLKP T YVFQIRA + +++P ++V TL EA + S +Q+P
Sbjct: 513 TVTVTNLKPATRYVFQIRAASPGPSWEAQSFNPSIEVQTLG-------EAASGSRDQSPA 565
Query: 556 IIIAVVAVAGTIILVFMVFGFIIGRRHCGYSK--ADQEGDEELYFHFKFPGTKTYIDPET 613
I++ VV ++ ++L ++ I RR C Y K D +EELYFHFK P +T++DP++
Sbjct: 566 IVVTVVTISALLVLGSVMSVLAIWRRPCSYGKGGGDAHDEEELYFHFKVPTRRTFLDPQS 625
Query: 614 YEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTE 673
D +AVH FAKELDA + +ER +G G FGE+C G L+LPG++++ VA+ L+ ++
Sbjct: 626 CGDLLQAVHLFAKELDAKSVTLERSLGGGRFGELCCGCLQLPGRQELLVAVHMLRDSASD 685
Query: 674 KQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVI 733
QR FL EA +GQFDH ++V LEGVVTRG +MIV E+M +GALD FLR+H+GQ
Sbjct: 686 SQRLGFLAEALTLGQFDHSHIVRLEGVVTRGSTLMIVTEYMSHGALDGFLRRHEGQLVAG 745
Query: 734 QLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTT 793
QL+G+L G+A+ M+YL++MGYVHR LAAR++LV+S+LVCK+S FG R D EAVYTT
Sbjct: 746 QLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVSSDLVCKISGFG--RGPRDRSEAVYTT 803
Query: 794 TGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGY 853
G+ P W APE +Q+ F+SASDVWS+GI+MWEVM++GERPYWDMS QDVIKA+E+G+
Sbjct: 804 MSGRSPALWAAPETLQFGHFSSASDVWSFGIIMWEVMAFGERPYWDMSGQDVIKAVEDGF 863
Query: 854 RLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPNSLKTPLGTCSRPISP 913
RLP P +CP LH+LMLDCWQK+ ERP+F QI IL KM+++P K L TC RP +P
Sbjct: 864 RLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSILSKMVQDPEPPKCALTTCPRPPTP 923
Query: 914 LLDQNTPDFTTFCSVGEWLQAIKMERYKDNFTAAGYNSLESVARMTIEDVMSLGITLVGH 973
L D+ F +F SVG WL+A+ + RYKD+F AAGY SLE+VA MT +D++SLGI+L H
Sbjct: 924 LADRAFSTFPSFGSVGAWLEALDLCRYKDSFAAAGYGSLEAVAEMTAQDLVSLGISLAEH 983
Query: 974 QKKIMSSIQTMRAQMLHLHGTGIQV 998
++ ++S I ++A++L L G G+QV
Sbjct: 984 REALLSGISALQARVLQLQGQGVQV 1008
>gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens]
Length = 998
Score = 1076 bits (2783), Expect = 0.0
Identities = 551/969 (56%), Positives = 688/969 (71%), Gaps = 25/969 (2%)
Query: 30 AKEVLLLDSKAQQTELEWISSPPNGWEEISGLDENYTPIRTYQVCQVMEPNQNNWLRTNW 89
A E L+D+K +EL W S P +GWEE+SG DE PIRTYQVC V E +QNNWLRT +
Sbjct: 37 ALEETLMDTKWVTSELAWTSHPESGWEEVSGYDEAMNPIRTYQVCNVRESSQNNWLRTGF 96
Query: 90 ISKGNAQRIFVELKFTLRDCNSLPGVLGTCKETFNLYYYETDYDTGRNIR----ENLYVK 145
I + + QR++VELKFT+RDCNS+P + G+CKETFNL+YYE D D EN YVK
Sbjct: 97 IWRRDVQRVYVELKFTVRDCNSIPNIPGSCKETFNLFYYEADSDVASASSPFWMENPYVK 156
Query: 146 IDTIAADESFTQGDLGERKMKLNTEVREIGPLSKKGFYLAFQDVGACIALVSVKVYYKKC 205
+DTIA DESF++ D G ++NT+VR GPLSK GFYLAFQD GAC++L+SV+ +YKKC
Sbjct: 157 VDTIAPDESFSRLDAG----RVNTKVRSFGPLSKAGFYLAFQDQGACMSLISVRAFYKKC 212
Query: 206 WSIIENLAIFPDTVTGSEFSSLVEVRGTCVSSAEEEAENAPRMHCSAEGEWLVPIGKCIC 265
S A+FP+T+TG+E +SLV GTC+ +A E + +++C+ +GEW+VP+G C C
Sbjct: 213 ASTTAGFALFPETLTGAEPTSLVIAPGTCIPNAVEVSVPL-KLYCNGDGEWMVPVGACTC 271
Query: 266 KAGYQQ--KGDTCEPCGRGFYKSSSQDLQCSRCPTHSFSDKEGSSRCECEDGYYRAPSDP 323
G++ K C PC G YK+ + C CP +S + +S C C + +YRA SD
Sbjct: 272 ATGHEPAAKESQCRPCPPGSYKAKQGEGPCLPCPPNSRTTSPAASICTCHNNFYRADSDS 331
Query: 324 PYVACTRPPSAPQNLIFNINQTTVSLEWSPPADNGGRNDVTYRILCKRCSWEQGE--CVP 381
ACT PS P+ +I N+N+T++ LEWS P D GGR+D+ Y ++CK+C G C
Sbjct: 332 ADSACTTVPSPPRGVISNVNETSLILEWSEPRDLGGRDDLLYNVICKKCHGAGGASACSR 391
Query: 382 CGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFAAVSITTGQA 441
C N+ ++P+Q GL + V + LLAH YTFEV+AVNGVS S +AAV+ITT QA
Sbjct: 392 CDDNVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVNGVSGKSPLPPRYAAVNITTNQA 451
Query: 442 APSQVSGVMKERVLQRSVELSWQEPEHPNGVITEYEIKYYEKDQRERTYSTVKTKSTSAS 501
APS+V + S+ LSW PE PNGVI +YE+KY+EK E STV ++ S
Sbjct: 452 APSEVPTLRLHSSSGSSLTLSWAPPERPNGVILDYEMKYFEKS--EGIASTVTSQMNSVQ 509
Query: 502 INNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEATGKMFEATAVSSEQNPVIIIAVV 561
++ L+P YV Q+RA T AGYG YS + E T + EQ P+I+ +
Sbjct: 510 LDGLRPDARYVVQVRARTVAGYGQYSRPAEF----ETTSERGSGAQQLQEQLPLIVGS-- 563
Query: 562 AVAGTIILVFMVFGFIIGRRHCGYSKADQEGDEELYFHFKFPGTKTYIDPETYEDPNRAV 621
A AG + +V +V I+ R + +D E E+L + PG K YIDP TYEDPN AV
Sbjct: 564 ATAGLVFVVAVVVIAIVCLRKQRHG-SDSEYTEKLQQYIA-PGMKVYIDPFTYEDPNEAV 621
Query: 622 HQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLC 681
+FAKE+D SC+KIE VIGAGEFGEVC GRLK PG+R+V VAIKTLKVGYTE+QRRDFL
Sbjct: 622 REFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYTERQRRDFLS 681
Query: 682 EASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGMLRG 741
EASIMGQFDHPN++ LEGVVT+ +PVMI+ EFMEN ALD+FLR +DGQFTVIQLVGMLRG
Sbjct: 682 EASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRG 741
Query: 742 IAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDP-EAVYTTT-GGKIP 799
IAAGM+YL++M YVHRDLAARNILVNSNLVCKVSDFGLSR +EDDP + YT++ GGKIP
Sbjct: 742 IAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIP 801
Query: 800 VRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPAPM 859
+RWTAPEAI YRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVI A+E+ YRLP PM
Sbjct: 802 IRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPM 861
Query: 860 DCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPNSLKTPLGTCSRPISPLLDQNT 919
DCP LHQLMLDCW ++R RPKF QIV LDK+IRN SLK S PLLD+
Sbjct: 862 DCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAASLKVIASAQSGMSQPLLDRTV 921
Query: 920 PDFTTFCSVGEWLQAIKMERYKDNFTAAGYNSLESVARMTIEDVMSLGITLVGHQKKIMS 979
PD+TTF +VG+WL AIKM RYK++F +AG+ S + VA+MT ED++ +G+TL GHQKKI+S
Sbjct: 922 PDYTTFTTVGDWLDAIKMGRYKESFVSAGFASFDLVAQMTAEDLLRIGVTLAGHQKKILS 981
Query: 980 SIQTMRAQM 988
SIQ MR QM
Sbjct: 982 SIQDMRLQM 990
>gi|32967311 ephrin receptor EphA2 [Homo sapiens]
Length = 976
Score = 993 bits (2566), Expect = 0.0
Identities = 504/979 (51%), Positives = 659/979 (67%), Gaps = 28/979 (2%)
Query: 16 IWLLRFAHTGEAQAAKEVLLLDSKAQQTELEWISSP-PNGWEEISGLDENYTPIRTYQVC 74
+W A AQ KEV+LLD A EL W++ P GW+ + + N PI Y VC
Sbjct: 13 LWGCALAAAAAAQG-KEVVLLDFAAAGGELGWLTHPYGKGWDLMQNI-MNDMPIYMYSVC 70
Query: 75 QVMEPNQNNWLRTNWISKGNAQRIFVELKFTLRDCNSLPGVLGTCKETFNLYYYETDYDT 134
VM +Q+NWLRTNW+ +G A+RIF+ELKFT+RDCNS PG +CKETFNLYY E+D D
Sbjct: 71 NVMSGDQDNWLRTNWVYRGEAERIFIELKFTVRDCNSFPGGASSCKETFNLYYAESDLDY 130
Query: 135 GRNIRENLYVKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSKKGFYLAFQDVGACIA 194
G N ++ L+ KIDTIA DE D R +KLN E R +GPL++KGFYLAFQD+GAC+A
Sbjct: 131 GTNFQKRLFTKIDTIAPDEITVSSDFEARHVKLNVEERSVGPLTRKGFYLAFQDIGACVA 190
Query: 195 LVSVKVYYKKCWSIIENLAIFPDTVTGSEFSSLVEVRGTCVSSAE-EEAENAPRMHCSAE 253
L+SV+VYYKKC +++ LA FP+T+ GS+ SL V GTCV A PRMHC+ +
Sbjct: 191 LLSVRVYYKKCPELLQGLAHFPETIAGSDAPSLATVAGTCVDHAVVPPGGEEPRMHCAVD 250
Query: 254 GEWLVPIGKCICKAGYQQKGDTCEPCGRGFYKSSSQDLQCSRCPTHSFSDKEGSSRCECE 313
GEWLVPIG+C+C+AGY++ D C+ C GF+K + + C CP H+ EG++ CECE
Sbjct: 251 GEWLVPIGQCLCQAGYEKVEDACQACSPGFFKFEASESPCLECPEHTLPSPEGATSCECE 310
Query: 314 DGYYRAPSDPPYVACTRPPSAPQNLIFNINQTTVSLEWSPPADNGGRNDVTYRILCKRCS 373
+G++RAP DP + CTRPPSAP L V L W+PP D+GGR D+ Y + C++C
Sbjct: 311 EGFFRAPQDPASMPCTRPPSAPHYLTAVGMGAKVELRWTPPQDSGGREDIVYSVTCEQCW 370
Query: 374 WEQGECVPCGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFAA 433
E GEC PC +++ Y GL VTV DL H NYTF VEA NGVS L S R F
Sbjct: 371 PESGECGPCEASVRYSEPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSGLVTS-RSFRT 429
Query: 434 VSITTGQAAPSQVSGVMKERVLQRSVELSWQEPEHPNGVITEYEIKYYEKDQRERTYSTV 493
S++ Q P +V E S+ +SW P + +YE+ Y +K +Y+
Sbjct: 430 ASVSINQTEPPKVR---LEGRSTTSLSVSWSIPPPQQSRVWKYEVTYRKKGD-SNSYNVR 485
Query: 494 KTKSTSASINNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEATGKMFEATAVSSE-Q 552
+T+ S ++++L P T Y+ Q++A T G G A K+ E +S E
Sbjct: 486 RTEGFSVTLDDLAPDTTYLVQVQALTQEGQG-------------AGSKVHEFQTLSPEGS 532
Query: 553 NPVIIIAVVAVAGTIILVFMVFGFIIGRRHCGYSKADQEGDEELYFHF--KFPGTKTYID 610
+ +I VAV ++LV GF I RR ++ ++ E++YF + KTY+D
Sbjct: 533 GNLAVIGGVAVGVVLLLVLAGVGFFIHRRR--KNQRARQSPEDVYFSKSEQLKPLKTYVD 590
Query: 611 PETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLP-GKRDVAVAIKTLKV 669
P TYEDPN+AV +F E+ SC+ ++VIGAGEFGEV G LK GK++V VAIKTLK
Sbjct: 591 PHTYEDPNQAVLKFTTEIHPSCVTRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKA 650
Query: 670 GYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQ 729
GYTEKQR DFL EA IMGQF H N++ LEGV+++ KP+MI+ E+MENGALD FLR+ DG+
Sbjct: 651 GYTEKQRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGE 710
Query: 730 FTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEA 789
F+V+QLVGMLRGIAAGM+YLA+M YVHRDLAARNILVNSNLVCKVSDFGLSRV+EDDPEA
Sbjct: 711 FSVLQLVGMLRGIAAGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEA 770
Query: 790 VYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAI 849
YTT+GGKIP+RWTAPEAI YRKFTSASDVWS+GIVMWEVM+YGERPYW++SN +V+KAI
Sbjct: 771 TYTTSGGKIPIRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAI 830
Query: 850 EEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPNSLKTPLGTCSR 909
+G+RLP PMDCP+ ++QLM+ CWQ+ERA RPKF IV ILDK+IR P+SLKT R
Sbjct: 831 NDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIRAPDSLKTLADFDPR 890
Query: 910 PISPLLDQNTPDFTTFCSVGEWLQAIKMERYKDNFTAAGYNSLESVARMTIEDVMSLGIT 969
L + + F +V EWL++IKM++Y ++F AAGY ++E V +MT +D+ +G+
Sbjct: 891 VSIRLPSTSGSEGVPFRTVSEWLESIKMQQYTEHFMAAGYTAIEKVVQMTNDDIKRIGVR 950
Query: 970 LVGHQKKIMSSIQTMRAQM 988
L GHQK+I S+ ++ Q+
Sbjct: 951 LPGHQKRIAYSLLGLKDQV 969
>gi|32528301 EPH receptor B4 precursor [Homo sapiens]
Length = 987
Score = 942 bits (2436), Expect = 0.0
Identities = 489/974 (50%), Positives = 647/974 (66%), Gaps = 31/974 (3%)
Query: 29 AAKEVLLLDSKAQQTELEWISSPP--NGWEEISGLDENYTPIRTYQVCQVME-PNQNNWL 85
AA E LL++K + +L+W++ P WEE+SGLDE +RTY+VC V P Q +WL
Sbjct: 14 AALEETLLNTKLETADLKWVTFPQVDGQWEELSGLDEEQHSVRTYEVCDVQRAPGQAHWL 73
Query: 86 RTNWISKGNAQRIFVELKFTLRDCNSLPGVLGTCKETFNLYYYETDYDTGRNIR----EN 141
RT W+ + A ++ L+FT+ +C SLP +CKETF ++YYE+D DT + EN
Sbjct: 74 RTGWVPRRGAVHVYATLRFTMLECLSLPRAGRSCKETFTVFYYESDADTATALTPAWMEN 133
Query: 142 LYVKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSKKGFYLAFQDVGACIALVSVKVY 201
Y+K+DT+AA+ + E K+N + +GPLSK GFYLAFQD GAC+AL+S+ ++
Sbjct: 134 PYIKVDTVAAEHLTRKRPGAEATGKVNVKTLRLGPLSKAGFYLAFQDQGACMALLSLHLF 193
Query: 202 YKKCWSIIENLAIFPDTVTGSEFSSLVEVRGTCVSSAEEEAENAPRMHCSAEGEWLV-PI 260
YKKC + NL FP+TV +V V G+CV A +P ++C +G+W P+
Sbjct: 194 YKKCAQLTVNLTRFPETVPRE---LVVPVAGSCVVDAVPAPGPSPSLYCREDGQWAEQPV 250
Query: 261 GKCICKAGYQQ-KGDT-CEPCGRGFYKSSSQDLQCSRCPTHSFSDKEGSSRCECEDGYYR 318
C C G++ +G+T C C +G +K S + C CP +S S+ GS+ C+C GY+R
Sbjct: 251 TGCSCAPGFEAAEGNTKCRACAQGTFKPLSGEGSCQPCPANSHSNTIGSAVCQCRVGYFR 310
Query: 319 APSDPPYVACTRPPSAPQNLIFNINQTTVSLEWSPPADNGGRNDVTYRILCKRCSWEQGE 378
A +DP CT PPSAP++++ +N +++ LEWS P ++GGR D+TY + C+ C G
Sbjct: 311 ARTDPRGAPCTTPPSAPRSVVSRLNGSSLHLEWSAPLESGGREDLTYALRCRECR-PGGS 369
Query: 379 CVPCGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFAAVSITT 438
C PCG ++ + P L + +V V L YTFEV A+NGVS L+ F V++TT
Sbjct: 370 CAPCGGDLTFDPGPRDLVEPWVVVRGLRPDFTYTFEVTALNGVSSLATGPVPFEPVNVTT 429
Query: 439 GQAAPSQVSGVMKERVLQRSVELSWQEPEHPNGVITEYEIKYYEKD-QRERTYSTVKTKS 497
+ P VS + R S+ L+W P P+G + +YE+KY+EK + + +KT
Sbjct: 430 DREVPPAVSDIRVTRSSPSSLSLAWAVPRAPSGAVLDYEVKYHEKGAEGPSSVRFLKTSE 489
Query: 498 TSASINNLKPGTVYVFQIRAFTAAGYGNYSPRLDVAT-LEEATGKMFEATAVSSEQNPVI 556
A + LK G Y+ Q+RA + AGYG + T L+E+ G + +
Sbjct: 490 NRAELRGLKRGASYLVQVRARSEAGYGPFGQEHHSQTQLDESEGW----------REQLA 539
Query: 557 IIAVVAVAGTI-ILVFMVFGFIIGRRHCGYSKADQEGDEELYFHFKFPGTKTYIDPETYE 615
+IA AV G + +LV +V + R+ +A+ Y GTK YIDP TYE
Sbjct: 540 LIAGTAVVGVVLVLVVIVVAVLCLRKQSNGREAEYSDKHGQYLIGH--GTKVYIDPFTYE 597
Query: 616 DPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQ 675
DPN AV +FAKE+D S +KIE VIGAGEFGEVC GRLK PGK++ VAIKTLK GYTE+Q
Sbjct: 598 DPNEAVREFAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQ 657
Query: 676 RRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQL 735
RR+FL EASIMGQF+HPN++ LEGVVT PVMI+ EFMENGALD+FLR +DGQFTVIQL
Sbjct: 658 RREFLSEASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLNDGQFTVIQL 717
Query: 736 VGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDD-PEAVYTTT 794
VGMLRGIA+GMRYLA+M YVHRDLAARNILVNSNLVCKVSDFGLSR +E++ + YT++
Sbjct: 718 VGMLRGIASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSS 777
Query: 795 -GGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGY 853
GGKIP+RWTAPEAI +RKFTSASD WSYGIVMWEVMS+GERPYWDMSNQDVI AIE+ Y
Sbjct: 778 LGGKIPIRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDY 837
Query: 854 RLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPNSLKTPLGTCSRPISP 913
RLP P DCP LHQLMLDCWQK+R RP+F Q+V LDKMIRNP SLK P
Sbjct: 838 RLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKMIRNPASLKIVARENGGASHP 897
Query: 914 LLDQNTPDFTTFCSVGEWLQAIKMERYKDNFTAAGYNSLESVARMTIEDVMSLGITLVGH 973
LLDQ P ++ F SVGEWL+AIKM RY+++F AAG+ S E V++++ ED++ +G+TL GH
Sbjct: 898 LLDQRQPHYSAFGSVGEWLRAIKMGRYEESFAAAGFGSFELVSQISAEDLLRIGVTLAGH 957
Query: 974 QKKIMSSIQTMRAQ 987
QKKI++S+Q M++Q
Sbjct: 958 QKKILASVQHMKSQ 971
>gi|221316650 ephrin receptor EphA1 [Homo sapiens]
Length = 976
Score = 808 bits (2087), Expect = 0.0
Identities = 445/993 (44%), Positives = 617/993 (62%), Gaps = 45/993 (4%)
Query: 10 WIILCYIWLLRFAHTGEAQAAKEVLLLDSKAQQTELEWISSPP-NGWEEISGLDENYTPI 68
W + + LL A AKEV L+D+ Q EL W+ PP +GW E + N TP+
Sbjct: 5 WPLGLGLVLLLCAPLPPGARAKEVTLMDTSKAQGELGWLLDPPKDGWSEQQQI-LNGTPL 63
Query: 69 RTYQVCQVM-EPNQNNWLRTNWISKGN-AQRIFVELKFTLRDCNSLPGVLGT--CKETFN 124
YQ C + + ++WLR+NWI +G A R+ VEL+FT+RDC S PG G CKETFN
Sbjct: 64 YMYQDCPMQGRRDTDHWLRSNWIYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCKETFN 123
Query: 125 LYYYETDYDTGRNIRENLYVKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSKKGFYL 184
L Y E+D D G +R L+ K+ T+AAD+SFT DL +KLN E +G L+++G YL
Sbjct: 124 LLYMESDQDVGIQLRRPLFQKVTTVAADQSFTIRDLVSGSVKLNVERCSLGRLTRRGLYL 183
Query: 185 AFQDVGACIALVSVKVYYKKCWSIIENLAIFPDTVTGSEFSSLVEVRGTCV--SSAEEEA 242
AF + GAC+ALVSV+V+Y++C + LA FPDT+ G + LVEV GTC+ + A
Sbjct: 184 AFHNPGACVALVSVRVFYQRCPETLNGLAQFPDTLPGP--AGLVEVAGTCLPHARASPRP 241
Query: 243 ENAPRMHCSAEGEWLVPIGKCICKAGYQQ--KGDTCEPCGRGFYKSSSQDLQCSRCPTHS 300
APRMHCS +GEWLVP+G+C C+ GY++ G+ C C G Y+ C CP S
Sbjct: 242 SGAPRMHCSPDGEWLVPVGRCHCEPGYEEGGSGEACVACPSGSYRMDMDTPHCLTCPQQS 301
Query: 301 FSDKEGSSRCECEDGYYRAPSDPPYVACTRPPSAPQNLIFNINQTTVSLEWSPPADNGGR 360
++ EG++ C CE G+YRAP + P VACT PPSAP+NL F+ + T +SL W PPAD GGR
Sbjct: 302 TAESEGATICTCESGHYRAPGEGPQVACTGPPSAPRNLSFSASGTQLSLRWEPPADTGGR 361
Query: 361 NDVTYRILCKRC---SWEQGECVPCGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEA 417
DV Y + C +C + + G C PCG + + P GL V V L +ANYTF VEA
Sbjct: 362 QDVRYSVRCSQCQGTAQDGGPCQPCGVGVHFSPGARGLTTPAVHVNGLEPYANYTFNVEA 421
Query: 418 VNGVSDLSRSQRLFAAVSITTGQAAPSQVSGVMKERVLQ--RSVELSW--QEPEHPNGVI 473
NGVS L S +VSI+ G A +SG+ V + R +EL+W P P +
Sbjct: 422 QNGVSGLGSSGHASTSVSISMGHA--ESLSGLSLRLVKKEPRQLELTWAGSRPRSPGANL 479
Query: 474 TEYEIKYYEKDQRERTYSTVKTKSTSASINNLKPGTVYVFQIRAFTAAGYGNYSPRLDVA 533
T YE+ +D+ ER ++ + + L+P T Y+ ++R T G G +SP +
Sbjct: 480 T-YELHVLNQDE-ERYQMVLEPR---VLLTELQPDTTYIVRVRMLTPLGPGPFSPDHEFR 534
Query: 534 TLEEATGKMFEATAVSSEQNPVIIIAVVAVAGTIILVFMVFGFIIGRRHCGYSKADQEGD 593
T + + V+ +I + + ++L +VF +R + D+ D
Sbjct: 535 TSPPVSRGLTGGEIVA-------VIFGLLLGAALLLGILVFRSRRAQRQRQQRQRDRATD 587
Query: 594 ----EELYFHFKFPGTKTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCS 649
++L+ K Y+D + YEDP + F +ELD + + ++ VIG GEFGEV
Sbjct: 588 VDREDKLWL-------KPYVDLQAYEDPAQGALDFTRELDPAWLMVDTVIGEGEFGEVYR 640
Query: 650 GRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMI 709
G L+LP + VAIKTLK Q +FL EA+IMGQF HP+++HLEGVVT+ KP+MI
Sbjct: 641 GTLRLPSQDCKTVAIKTLKDTSPGGQWWNFLREATIMGQFSHPHILHLEGVVTKRKPIMI 700
Query: 710 VIEFMENGALDAFLRKHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSN 769
+ EFMENGALDAFLR+ + Q QLV ML+GIA+GM YL++ YVHRDLAARNILVN N
Sbjct: 701 ITEFMENGALDAFLREREDQLVPGQLVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQN 760
Query: 770 LVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEV 829
L CKVSDFGL+R++ DD + Y T GGKIP+RWTAPEAI +R FT+ASDVWS+GIVMWEV
Sbjct: 761 LCCKVSDFGLTRLL-DDFDGTYETQGGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEV 819
Query: 830 MSYGERPYWDMSNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGI 889
+S+G++PY +MSNQ+V+K+IE+GYRLP P+DCPA L++LM +CW +RA RP F+++
Sbjct: 820 LSFGDKPYGEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKLQAH 879
Query: 890 LDKMIRNPNSLKTPLGTCSRPISPLLDQNTPDFTTFCSVGEWLQAIKMERYKDNFTAAGY 949
L++++ NP+SL+T R L + D + +V EWL++I+M+RY +F +AG
Sbjct: 880 LEQLLANPHSLRTIANFDPRMTLRLPSLSGSDGIPYRTVSEWLESIRMKRYILHFHSAGL 939
Query: 950 NSLESVARMTIEDVMSLGITLVGHQKKIMSSIQ 982
+++E V +T ED+ +GITL GHQK+I+ SIQ
Sbjct: 940 DTMECVLELTAEDLTQMGITLPGHQKRILCSIQ 972
>gi|194097332 ephrin receptor EphB6 precursor [Homo sapiens]
Length = 1021
Score = 785 bits (2028), Expect = 0.0
Identities = 417/1026 (40%), Positives = 617/1026 (60%), Gaps = 77/1026 (7%)
Query: 12 ILCYIWLLRFAHTGEAQAAKEVLLLDSKAQQTELEWISSPPNGWEEISGLDENYTPIRTY 71
++C +W+L + A E +LLD+ + +E+ W++ PP GW+E+S LD+ RT+
Sbjct: 16 MVCSLWVLLLV---SSVLALEEVLLDTTGETSEIGWLTYPPGGWDEVSVLDDQRRLTRTF 72
Query: 72 QVCQVMEP----NQNNWLRTNWISKGNAQRIFVELKFTLRDCNSLPGVLGTCKETFNLYY 127
+ C V Q+NWL+T+++ + AQR + L F++R C+SL GTC+ETF LYY
Sbjct: 73 EACHVAGAPPGTGQDNWLQTHFVERRGAQRAHIRLHFSVRACSSLGVSGGTCRETFTLYY 132
Query: 128 YETDY----DTGRNIRENLYVKIDTIAADESFTQGD-----------------LGERK-M 165
+ + D+ + + K+DTIAADESF G+R +
Sbjct: 133 RQAEEPDSPDSVSSWHLKRWTKVDTIAADESFPSSSSSSSSSSSAAWAVGPHGAGQRAGL 192
Query: 166 KLNTEVREIGPLSKKGFYLAFQDVGACIALVSVKVYYKKCWSIIENLAIFPDT-VTGSEF 224
+LN + R GPL+++GFY+AFQD GAC+ALV+V+++ C +++ + A FP+T +G+
Sbjct: 193 QLNVKERSFGPLTQRGFYVAFQDTGACLALVAVRLFSYTCPAVLRSFASFPETQASGAGG 252
Query: 225 SSLVEVRGTCVSSAEEEAENA--------PRMHCSAEGEWLVPIGKCICKAGYQQ-KGD- 274
+SLV GTCV+ AE E + PR+HC+ EG+W+V +G C C+ GYQ +GD
Sbjct: 253 ASLVAAVGTCVAHAEPEEDGVGGQAGGSPPRLHCNGEGKWMVAVGGCRCQPGYQPARGDK 312
Query: 275 TCEPCGRGFYKSSSQDLQCSRCPTHSFSDKEGSSRCECEDGYYRAPSDPPYVACTRPPSA 334
C+ C RG YKSS+ + CS CP S + + C C +G+YRA SDPP CT PPSA
Sbjct: 313 ACQACPRGLYKSSAGNAPCSPCPARSHAPNPAAPVCPCLEGFYRASSDPPEAPCTGPPSA 372
Query: 335 PQNLIFNINQTTVSLEWSPPADNGGRNDVTYRILCKRCSWEQ-------GECVPCGSNIG 387
PQ L F + + + L W P + GGR D+ + ++CK C Q G C C +
Sbjct: 373 PQELWFEVQGSALMLHWRLPRELGGRGDLLFNVVCKECEGRQEPASGGGGTCHRCRDEVH 432
Query: 388 YMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFAAVSITTGQAAPSQVS 447
+ P+Q GL ++ V V L AH Y EV+AVNGVS+LS AA++++T PS V
Sbjct: 433 FDPRQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAAINVSTSHEVPSAVP 492
Query: 448 GVMKERVLQRSVELSWQEPEHPNGVITEYEIKYYEKDQRERTYSTVKTKSTSASINNLKP 507
V + S+ +SW +P+ NG I +Y+++YY++ + E T+ +++ +A++ L P
Sbjct: 493 VVHQVSRASNSITVSWPQPDQTNGNILDYQLRYYDQAEDESHSFTLTSETNTATVTQLSP 552
Query: 508 GTVYVFQIRAFTAAGYGNYSPRLDVATLEEATGKMFEATAVSSEQNPVIIIAVVAVAGTI 567
G +Y FQ+RA TAAG+G Y ++ TL + E ++ E+ ++I +++ +
Sbjct: 553 GHIYGFQVRARTAAGHGPYGGKVYFQTLPQG-----ELSSQLPERLSLVIGSILGALAFL 607
Query: 568 ILVFMVFGFII---GRRHCGYSKADQEGDEELYFHFKFPG--TKTYIDPETYEDPNRAVH 622
+L + ++ RR GY++ Q+ + PG K YIDP TYEDP +A+
Sbjct: 608 LLAAITVLAVVFQRKRRGTGYTEQLQQ--------YSSPGLGVKYYIDPSTYEDPCQAIR 659
Query: 623 QFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCE 682
+ A+E+D + IKIE VIG G FGEV GRL+ G+R+ VAI+ L G E + FL
Sbjct: 660 ELAREVDPAYIKIEEVIGTGSFGEVRQGRLQPRGRREQTVAIQALWAGGAESLQMTFLGR 719
Query: 683 ASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGMLRGI 742
A+++GQF HPN++ LEGVVT+ +P+M++ EFME G LD+FLR+ +GQF+ +QLV M RG+
Sbjct: 720 AAVLGQFQHPNILRLEGVVTKSRPLMVLTEFMELGPLDSFLRQREGQFSSLQLVAMQRGV 779
Query: 743 AAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRW 802
AA M+YL+ +VHR L+A ++LVNS+LVCKV+ G ++ G +RW
Sbjct: 780 AAAMQYLSSFAFVHRSLSAHSVLVNSHLVCKVARLG------------HSPQGPSCLLRW 827
Query: 803 TAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPAPMDCP 862
APE I + K T++SDVWS+GI+MWEVMSYGERPYWDMS Q+V+ AIE+ +RLP P CP
Sbjct: 828 AAPEVIAHGKHTTSSDVWSFGILMWEVMSYGERPYWDMSEQEVLNAIEQEFRLPPPPGCP 887
Query: 863 AGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPNSLKTPLGTCSRPISPLLDQNTPDF 922
GLH LMLD WQK+RA RP F+Q+V DKMIR P++L+ RP LL DF
Sbjct: 888 PGLHLLMLDTWQKDRARRPHFDQLVAAFDKMIRKPDTLQAGGDPGERPSQALLTPVALDF 947
Query: 923 TTFCSVGEWLQAIKMERYKDNFTAAGYNSLESVARMTIEDVMSLGITLVGHQKKIMSSIQ 982
S WL AI +E Y+DNF+ G + VA++++ED+ +LGITL GHQKK++ IQ
Sbjct: 948 PCLDSPQAWLSAIGLECYQDNFSKFGLCTFSDVAQLSLEDLPALGITLAGHQKKLLHHIQ 1007
Query: 983 TMRAQM 988
++ +
Sbjct: 1008 LLQQHL 1013
>gi|32967314 ephrin receptor EphA3 isoform b precursor [Homo
sapiens]
Length = 539
Score = 675 bits (1741), Expect = 0.0
Identities = 312/507 (61%), Positives = 402/507 (79%), Gaps = 3/507 (0%)
Query: 28 QAAKEVLLLDSKAQQTELEWISSPPNGWEEISGLDENYTPIRTYQVCQVMEPNQNNWLRT 87
Q + EV LLDSK Q EL WIS P +GWEEISG+DE+YTPIRTYQVC VM+ +QNNWLRT
Sbjct: 25 QPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRT 84
Query: 88 NWISKGNAQRIFVELKFTLRDCNSLPGVLGTCKETFNLYYYETDYDTGRNIRENLYVKID 147
NW+ + +AQ+I+VELKFTLRDCNS+P VLGTCKETFNLYY E+D D G RE+ + KID
Sbjct: 85 NWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVKFREHQFTKID 144
Query: 148 TIAADESFTQGDLGERKMKLNTEVREIGPLSKKGFYLAFQDVGACIALVSVKVYYKKCWS 207
TIAADESFTQ DLG+R +KLNTE+RE+GP++KKGFYLAFQDVGAC+ALVSV+VY+KKC
Sbjct: 145 TIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPF 204
Query: 208 IIENLAIFPDTVTGSEFSSLVEVRGTCVSSAEEEAENAPRMHCSAEGEWLVPIGKCICKA 267
++NLA+FPDTV + SLVEVRG+CV++++EE + PRM+CS EGEWLVPIGKC C A
Sbjct: 205 TVKNLAMFPDTVP-MDSQSLVEVRGSCVNNSKEE--DPPRMYCSTEGEWLVPIGKCSCNA 261
Query: 268 GYQQKGDTCEPCGRGFYKSSSQDLQCSRCPTHSFSDKEGSSRCECEDGYYRAPSDPPYVA 327
GY+++G C+ C GFYK+ +++C++CP HS + ++GS C CE+ Y+RA DPP +A
Sbjct: 262 GYEERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSMA 321
Query: 328 CTRPPSAPQNLIFNINQTTVSLEWSPPADNGGRNDVTYRILCKRCSWEQGECVPCGSNIG 387
CTRPPS+P+N+I NIN+T+V L+WS P D GGR DVT+ I+CK+C W +C PC N+
Sbjct: 322 CTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVR 381
Query: 388 YMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFAAVSITTGQAAPSQVS 447
++P+Q GL + VTV DLLAH NYTFE++AVNGVS+LS R FAAVSITT QAAPS V
Sbjct: 382 FLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVL 441
Query: 448 GVMKERVLQRSVELSWQEPEHPNGVITEYEIKYYEKDQRERTYSTVKTKSTSASINNLKP 507
+ K+R + S+ LSWQEPEHPNG+I +YE+KYYEK ++E +Y+ ++ + T+ +I++LKP
Sbjct: 442 TIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKP 501
Query: 508 GTVYVFQIRAFTAAGYGNYSPRLDVAT 534
T+YVFQIRA TAAGYG S + + T
Sbjct: 502 DTIYVFQIRARTAAGYGTNSRKFEFET 528
>gi|55770892 ephrin receptor EphA8 isoform 2 precursor [Homo
sapiens]
Length = 495
Score = 525 bits (1352), Expect = e-149
Identities = 242/420 (57%), Positives = 312/420 (74%), Gaps = 2/420 (0%)
Query: 22 AHTGEAQAAKEVLLLDSKAQQTELEWISSPPNGWEEISGLDENYTPIRTYQVCQVMEPNQ 81
A T + A EV LLD+ + W++ P +GW+ I+ +DE++ PI TYQVC VM PNQ
Sbjct: 21 AATCVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTYQVCNVMSPNQ 80
Query: 82 NNWLRTNWISKGNAQRIFVELKFTLRDCNSLPGVLGTCKETFNLYYYETDYDTGRNIREN 141
NNWLRT+W+ + A+R++ E+KFTLRDCNS+PGVLGTCKETFNLYY E+D D G + +E+
Sbjct: 81 NNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESDRDLGASTQES 140
Query: 142 LYVKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSKKGFYLAFQDVGACIALVSVKVY 201
++KIDTIAADESFT DLG R++KLNTEVR +GPLSK+GFYLAFQD+GAC+A++S+++Y
Sbjct: 141 QFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRIY 200
Query: 202 YKKCWSIIENLAIFPDTVTGSEFSSLVEVRGTCVSSAEEEAENAPRMHCSAEGEWLVPIG 261
YKKC +++ NLA F + VTG++ SSLVEVRG CV +EE + P+M+CSAEGEWLVPIG
Sbjct: 201 YKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEE--RDTPKMYCSAEGEWLVPIG 258
Query: 262 KCICKAGYQQKGDTCEPCGRGFYKSSSQDLQCSRCPTHSFSDKEGSSRCECEDGYYRAPS 321
KC+C AGY+++ D C C GFYKS+ D C+RCP HS S + C C+ YYRA
Sbjct: 259 KCVCSAGYEERRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYYRAAL 318
Query: 322 DPPYVACTRPPSAPQNLIFNINQTTVSLEWSPPADNGGRNDVTYRILCKRCSWEQGECVP 381
DPP ACTRPPSAP NLI ++N T+V+LEW+PP D GGR+D+TY +C+RC W C
Sbjct: 319 DPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCPWALSRCEA 378
Query: 382 CGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFAAVSITTGQA 441
CGS ++PQQT L + V +LLAH NY+F +EAVNGVSDLS R A V+ITT QA
Sbjct: 379 CGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAVVNITTNQA 438
>gi|150456469 EPH receptor A10 isoform 2 [Homo sapiens]
Length = 295
Score = 363 bits (932), Expect = e-100
Identities = 171/251 (68%), Positives = 205/251 (81%), Gaps = 3/251 (1%)
Query: 30 AKEVLLLDSKAQQTELEWISSPPNGWEEISGLDENYTPIRTYQVCQVMEPNQNNWLRTNW 89
A+EV+LLDSKA Q EL W + P NGWEEISG+DE+ PIRTYQVC V+EPNQ+NWL+T W
Sbjct: 33 AEEVILLDSKASQAELGWTALPSNGWEEISGVDEHDRPIRTYQVCNVLEPNQDNWLQTGW 92
Query: 90 ISKGNAQRIFVELKFTLRDCNSLPGVLGTCKETFNLYYYETDYDTGRN---IRENLYVKI 146
IS+G QRIFVEL+FTLRDC+S+PG GTCKETFN+YY ET+ D GR + + KI
Sbjct: 93 ISRGRGQRIFVELQFTLRDCSSIPGAAGTCKETFNVYYLETEADLGRGRPRLGGSRPRKI 152
Query: 147 DTIAADESFTQGDLGERKMKLNTEVREIGPLSKKGFYLAFQDVGACIALVSVKVYYKKCW 206
DTIAADESFTQGDLGERKMKLNTEVREIGPLS++GF+LAFQDVGAC+ALVSV+VYYK+C
Sbjct: 153 DTIAADESFTQGDLGERKMKLNTEVREIGPLSRRGFHLAFQDVGACVALVSVRVYYKQCR 212
Query: 207 SIIENLAIFPDTVTGSEFSSLVEVRGTCVSSAEEEAENAPRMHCSAEGEWLVPIGKCICK 266
+ + LA FP T S FS+LVEV GTCV+ +E E + PRMHC A+GEWLVP+G+C C
Sbjct: 213 ATVRGLATFPATAAESAFSTLVEVAGTCVAHSEGEPGSPPRMHCGADGEWLVPVGRCSCS 272
Query: 267 AGYQQKGDTCE 277
AG+Q++GD CE
Sbjct: 273 AGFQERGDFCE 283
>gi|30795229 hemopoietic cell kinase isoform p61HCK [Homo sapiens]
Length = 526
Score = 226 bits (575), Expect = 1e-58
Identities = 119/277 (42%), Positives = 173/277 (62%), Gaps = 12/277 (4%)
Query: 617 PNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQR 676
P + + A E+ +K+E+ +GAG+FGEV + VA+KT+K G +
Sbjct: 246 PQKPWEKDAWEIPRESLKLEKKLGAGQFGEVWMATYN----KHTKVAVKTMKPGSMSVEA 301
Query: 677 RDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVI-QL 735
FL EA++M H +V L VVT+ +P+ I+ EFM G+L FL+ +G + +L
Sbjct: 302 --FLAEANVMKTLQHDKLVKLHAVVTK-EPIYIITEFMAKGSLLDFLKSDEGSKQPLPKL 358
Query: 736 VGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTT- 794
+ IA GM ++ Y+HRDL A NILV+++LVCK++DFGL+RVIED+ YT
Sbjct: 359 IDFSAQIAEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLARVIEDNE---YTARE 415
Query: 795 GGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYR 854
G K P++WTAPEAI + FT SDVWS+GI++ E+++YG PY MSN +VI+A+E GYR
Sbjct: 416 GAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYR 475
Query: 855 LPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILD 891
+P P +CP L+ +M+ CW+ ERP FE I +LD
Sbjct: 476 MPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLD 512
>gi|4557665 insulin-like growth factor 1 receptor precursor [Homo
sapiens]
Length = 1367
Score = 222 bits (565), Expect = 2e-57
Identities = 150/447 (33%), Positives = 236/447 (52%), Gaps = 43/447 (9%)
Query: 456 QRSVELSWQEPEHPNGVITEYEIKYYEK--DQRERTYSTVKTKSTSASINNLKPGTVYVF 513
+ S+ L W EPE+PNG+I YEIKY + DQRE K A +N L PG Y
Sbjct: 845 ENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGN-YTA 903
Query: 514 QIRAFTAAGYGNYSPRLDVATLEEATGKMFEATAVSSEQNPVIIIAVVAVAGTIILVFMV 573
+I+A + +G G+++ + F A + +N + +I + VA +I+ +V
Sbjct: 904 RIQATSLSGNGSWTDPV-----------FFYVQAKTGYENFIHLIIALPVAVLLIVGGLV 952
Query: 574 FGFIIGRRHCGYSKADQEGDEELYFHFKFPGTKTYIDPETYEDPNRAVHQFAKELDASCI 633
+ R S+ G+ LY ++PE + + V E+ I
Sbjct: 953 IMLYVFHRKRNNSRL---GNGVLY---------ASVNPEYFSAADVYVPD-EWEVAREKI 999
Query: 634 KIERVIGAGEFGEVCSGRLK--LPGKRDVAVAIKTLKVGYTEKQRRDFLCEASIMGQFDH 691
+ R +G G FG V G K + + + VAIKT+ + ++R +FL EAS+M +F+
Sbjct: 1000 TMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNC 1059
Query: 692 PNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQF---------TVIQLVGMLRGI 742
+VV L GVV++G+P ++++E M G L ++LR + ++ +++ M I
Sbjct: 1060 HHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEI 1119
Query: 743 AAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGK--IPV 800
A GM YL +VHRDLAARN +V + K+ DFG++R D E Y GGK +PV
Sbjct: 1120 ADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTR---DIYETDYYRKGGKGLLPV 1176
Query: 801 RWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPAPMD 860
RW +PE+++ FT+ SDVWS+G+V+WE+ + E+PY +SN+ V++ + EG L P +
Sbjct: 1177 RWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDN 1236
Query: 861 CPAGLHQLMLDCWQKERAERPKFEQIV 887
CP L +LM CWQ RP F +I+
Sbjct: 1237 CPDMLFELMRMCWQYNPKMRPSFLEII 1263
>gi|27886593 PTK2 protein tyrosine kinase 2 isoform b [Homo sapiens]
Length = 1074
Score = 219 bits (558), Expect = 1e-56
Identities = 115/285 (40%), Positives = 170/285 (59%), Gaps = 7/285 (2%)
Query: 610 DPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKV 669
+ +TY P+ ++ +E I++ R IG G+FG+V G P +AVAIKT K
Sbjct: 425 EEDTYTMPSTRDYEIQRER----IELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKN 480
Query: 670 GYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQ 729
++ R FL EA M QFDHP++V L GV+T PV I++E G L +FL+
Sbjct: 481 CTSDSVREKFLQEALTMRQFDHPHIVKLIGVITEN-PVWIIMELCTLGELRSFLQVRKYS 539
Query: 730 FTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEA 789
+ L+ ++ + YL +VHRD+AARN+LV+SN K+ DFGLSR +ED
Sbjct: 540 LDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS--T 597
Query: 790 VYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAI 849
Y + GK+P++W APE+I +R+FTSASDVW +G+ MWE++ +G +P+ + N DVI I
Sbjct: 598 YYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRI 657
Query: 850 EEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMI 894
E G RLP P +CP L+ LM CW + + RP+F ++ L ++
Sbjct: 658 ENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTIL 702
>gi|24476013 PTK2 protein tyrosine kinase 2 isoform a [Homo sapiens]
Length = 1052
Score = 219 bits (558), Expect = 1e-56
Identities = 115/285 (40%), Positives = 170/285 (59%), Gaps = 7/285 (2%)
Query: 610 DPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKV 669
+ +TY P+ ++ +E I++ R IG G+FG+V G P +AVAIKT K
Sbjct: 403 EEDTYTMPSTRDYEIQRER----IELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKN 458
Query: 670 GYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQ 729
++ R FL EA M QFDHP++V L GV+T PV I++E G L +FL+
Sbjct: 459 CTSDSVREKFLQEALTMRQFDHPHIVKLIGVITEN-PVWIIMELCTLGELRSFLQVRKYS 517
Query: 730 FTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEA 789
+ L+ ++ + YL +VHRD+AARN+LV+SN K+ DFGLSR +ED
Sbjct: 518 LDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS--T 575
Query: 790 VYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAI 849
Y + GK+P++W APE+I +R+FTSASDVW +G+ MWE++ +G +P+ + N DVI I
Sbjct: 576 YYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRI 635
Query: 850 EEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMI 894
E G RLP P +CP L+ LM CW + + RP+F ++ L ++
Sbjct: 636 ENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTIL 680
>gi|4885661 viral oncogene yes-1 homolog 1 [Homo sapiens]
Length = 543
Score = 219 bits (557), Expect = 1e-56
Identities = 126/281 (44%), Positives = 172/281 (61%), Gaps = 12/281 (4%)
Query: 613 TYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYT 672
T + + + + A E+ +++E +G G FGEV G K VAIKTLK G
Sbjct: 257 TVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTK----VAIKTLKPGTM 312
Query: 673 EKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTV 732
+ FL EA IM + H +V L VV+ +P+ IV EFM G+L FL++ DG++
Sbjct: 313 MPEA--FLQEAQIMKKLRHDKLVPLYAVVSE-EPIYIVTEFMSKGSLLDFLKEGDGKYLK 369
Query: 733 I-QLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVY 791
+ QLV M IA GM Y+ M Y+HRDL A NILV NLVCK++DFGL+R+IED+ Y
Sbjct: 370 LPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLVCKIADFGLARLIEDNE---Y 426
Query: 792 TTT-GGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIE 850
T G K P++WTAPEA Y +FT SDVWS+GI+ E+++ G PY M N++V++ +E
Sbjct: 427 TARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQVE 486
Query: 851 EGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILD 891
GYR+P P CP LH+LM CW+K+ ERP FE I L+
Sbjct: 487 RGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYIQSFLE 527
>gi|4503823 protein-tyrosine kinase fyn isoform a [Homo sapiens]
Length = 537
Score = 218 bits (556), Expect = 2e-56
Identities = 116/267 (43%), Positives = 169/267 (63%), Gaps = 12/267 (4%)
Query: 627 ELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCEASIM 686
E+ +++ + +G G+FGEV G + VAIKTLK G + FL EA IM
Sbjct: 265 EIPRESLQLIKRLGNGQFGEVWMGTWN----GNTKVAIKTLKPGTMSPE--SFLEEAQIM 318
Query: 687 GQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVI-QLVGMLRGIAAG 745
+ H +V L VV+ +P+ IV E+M G+L FL+ +G+ + LV M +AAG
Sbjct: 319 KKLKHDKLVQLYAVVSE-EPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAG 377
Query: 746 MRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTT-GGKIPVRWTA 804
M Y+ M Y+HRDL + NILV + L+CK++DFGL+R+IED+ YT G K P++WTA
Sbjct: 378 MAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNE---YTARQGAKFPIKWTA 434
Query: 805 PEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPAPMDCPAG 864
PEA Y +FT SDVWS+GI++ E+++ G PY M+N++V++ +E GYR+P P DCP
Sbjct: 435 PEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPIS 494
Query: 865 LHQLMLDCWQKERAERPKFEQIVGILD 891
LH+LM+ CW+K+ ERP FE + L+
Sbjct: 495 LHELMIHCWKKDPEERPTFEYLQSFLE 521
>gi|38202217 proto-oncogene tyrosine-protein kinase SRC [Homo
sapiens]
Length = 536
Score = 218 bits (554), Expect = 3e-56
Identities = 123/269 (45%), Positives = 164/269 (60%), Gaps = 12/269 (4%)
Query: 625 AKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCEAS 684
A E+ +++E +G G FGEV G VAIKTLK G + FL EA
Sbjct: 262 AWEIPRESLRLEVKLGQGCFGEVWMGTWN----GTTRVAIKTLKPGTMSPEA--FLQEAQ 315
Query: 685 IMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVI-QLVGMLRGIA 743
+M + H +V L VV+ +P+ IV E+M G+L FL+ G++ + QLV M IA
Sbjct: 316 VMKKLRHEKLVQLYAVVSE-EPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIA 374
Query: 744 AGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTT-GGKIPVRW 802
+GM Y+ M YVHRDL A NILV NLVCKV+DFGL+R+IED+ YT G K P++W
Sbjct: 375 SGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNE---YTARQGAKFPIKW 431
Query: 803 TAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPAPMDCP 862
TAPEA Y +FT SDVWS+GI++ E+ + G PY M N++V+ +E GYR+P P +CP
Sbjct: 432 TAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECP 491
Query: 863 AGLHQLMLDCWQKERAERPKFEQIVGILD 891
LH LM CW+KE ERP FE + L+
Sbjct: 492 ESLHDLMCQCWRKEPEERPTFEYLQAFLE 520
>gi|4885609 proto-oncogene tyrosine-protein kinase SRC [Homo
sapiens]
Length = 536
Score = 218 bits (554), Expect = 3e-56
Identities = 123/269 (45%), Positives = 164/269 (60%), Gaps = 12/269 (4%)
Query: 625 AKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCEAS 684
A E+ +++E +G G FGEV G VAIKTLK G + FL EA
Sbjct: 262 AWEIPRESLRLEVKLGQGCFGEVWMGTWN----GTTRVAIKTLKPGTMSPEA--FLQEAQ 315
Query: 685 IMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVI-QLVGMLRGIA 743
+M + H +V L VV+ +P+ IV E+M G+L FL+ G++ + QLV M IA
Sbjct: 316 VMKKLRHEKLVQLYAVVSE-EPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIA 374
Query: 744 AGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTT-GGKIPVRW 802
+GM Y+ M YVHRDL A NILV NLVCKV+DFGL+R+IED+ YT G K P++W
Sbjct: 375 SGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNE---YTARQGAKFPIKW 431
Query: 803 TAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPAPMDCP 862
TAPEA Y +FT SDVWS+GI++ E+ + G PY M N++V+ +E GYR+P P +CP
Sbjct: 432 TAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECP 491
Query: 863 AGLHQLMLDCWQKERAERPKFEQIVGILD 891
LH LM CW+KE ERP FE + L+
Sbjct: 492 ESLHDLMCQCWRKEPEERPTFEYLQAFLE 520
>gi|119395738 insulin receptor isoform Short precursor [Homo sapiens]
Length = 1370
Score = 217 bits (552), Expect = 5e-56
Identities = 161/523 (30%), Positives = 254/523 (48%), Gaps = 47/523 (8%)
Query: 388 YMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFAAVSITTGQAAPSQVS 447
+ P + + + + L Y E++A N + R + T +A +
Sbjct: 783 HRPFEKVVNKESLVISGLRHFTGYRIELQACNQDTPEERCSVAAYVSARTMPEAKADDIV 842
Query: 448 GVMKERVLQRSV-ELSWQEPEHPNGVITEYEIKYYEKDQRERTYSTVKTK----STSASI 502
G + + + +V L WQEP+ PNG+I YE+ Y E + V K +
Sbjct: 843 GPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEE-LHLCVSRKHFALERGCRL 901
Query: 503 NNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEATGKMFEATAVSSEQNPVIIIAVVA 562
L PG Y +IRA + AG G+++ E + + V S +II
Sbjct: 902 RGLSPGN-YSVRIRATSLAGNGSWT--------EPTYFYVTDYLDVPSNIAKIII----- 947
Query: 563 VAGTIILVFMVFGFIIGRRHCGYSKADQEGDEELYFHFKFPGTKTYID--PETYEDPNRA 620
G +I VF+ F +IG + K +G + P + D P + P+
Sbjct: 948 --GPLIFVFL-FSVVIGSIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEW 1004
Query: 621 VHQFAKELDASCIKIERVIGAGEFGEVCSGRLK--LPGKRDVAVAIKTLKVGYTEKQRRD 678
E+ I + R +G G FG V G + + G+ + VA+KT+ + ++R +
Sbjct: 1005 ------EVSREKITLLRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIE 1058
Query: 679 FLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQF-------- 730
FL EAS+M F +VV L GVV++G+P ++V+E M +G L ++LR +
Sbjct: 1059 FLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPP 1118
Query: 731 -TVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEA 789
T+ +++ M IA GM YL +VHRDLAARN +V + K+ DFG++R D E
Sbjct: 1119 PTLQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTR---DIYET 1175
Query: 790 VYTTTGGK--IPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIK 847
Y GGK +PVRW APE+++ FT++SD+WS+G+V+WE+ S E+PY +SN+ V+K
Sbjct: 1176 DYYRKGGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLK 1235
Query: 848 AIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGIL 890
+ +G L P +CP + LM CWQ RP F +IV +L
Sbjct: 1236 FVMDGGYLDQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVNLL 1278
>gi|119395736 insulin receptor isoform Long precursor [Homo sapiens]
Length = 1382
Score = 217 bits (552), Expect = 5e-56
Identities = 161/523 (30%), Positives = 254/523 (48%), Gaps = 47/523 (8%)
Query: 388 YMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFAAVSITTGQAAPSQVS 447
+ P + + + + L Y E++A N + R + T +A +
Sbjct: 795 HRPFEKVVNKESLVISGLRHFTGYRIELQACNQDTPEERCSVAAYVSARTMPEAKADDIV 854
Query: 448 GVMKERVLQRSV-ELSWQEPEHPNGVITEYEIKYYEKDQRERTYSTVKTK----STSASI 502
G + + + +V L WQEP+ PNG+I YE+ Y E + V K +
Sbjct: 855 GPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEE-LHLCVSRKHFALERGCRL 913
Query: 503 NNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEATGKMFEATAVSSEQNPVIIIAVVA 562
L PG Y +IRA + AG G+++ E + + V S +II
Sbjct: 914 RGLSPGN-YSVRIRATSLAGNGSWT--------EPTYFYVTDYLDVPSNIAKIII----- 959
Query: 563 VAGTIILVFMVFGFIIGRRHCGYSKADQEGDEELYFHFKFPGTKTYID--PETYEDPNRA 620
G +I VF+ F +IG + K +G + P + D P + P+
Sbjct: 960 --GPLIFVFL-FSVVIGSIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEW 1016
Query: 621 VHQFAKELDASCIKIERVIGAGEFGEVCSGRLK--LPGKRDVAVAIKTLKVGYTEKQRRD 678
E+ I + R +G G FG V G + + G+ + VA+KT+ + ++R +
Sbjct: 1017 ------EVSREKITLLRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIE 1070
Query: 679 FLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQF-------- 730
FL EAS+M F +VV L GVV++G+P ++V+E M +G L ++LR +
Sbjct: 1071 FLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPP 1130
Query: 731 -TVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEA 789
T+ +++ M IA GM YL +VHRDLAARN +V + K+ DFG++R D E
Sbjct: 1131 PTLQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTR---DIYET 1187
Query: 790 VYTTTGGK--IPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIK 847
Y GGK +PVRW APE+++ FT++SD+WS+G+V+WE+ S E+PY +SN+ V+K
Sbjct: 1188 DYYRKGGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLK 1247
Query: 848 AIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGIL 890
+ +G L P +CP + LM CWQ RP F +IV +L
Sbjct: 1248 FVMDGGYLDQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVNLL 1290
>gi|162287326 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog
isoform B [Homo sapiens]
Length = 491
Score = 216 bits (550), Expect = 9e-56
Identities = 116/277 (41%), Positives = 173/277 (62%), Gaps = 11/277 (3%)
Query: 617 PNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQR 676
P + + A E+ IK+ + +GAG+FGEV G K VA+KTLK G Q
Sbjct: 210 PQKPWDKDAWEIPRESIKLVKRLGAGQFGEVWMGYYNNSTK----VAVKTLKPGTMSVQA 265
Query: 677 RDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVI-QL 735
FL EA++M H +V L VVTR +P+ I+ E+M G+L FL+ +G ++ +L
Sbjct: 266 --FLEEANLMKTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPKL 323
Query: 736 VGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTT- 794
+ IA GM Y+ Y+HRDL A N+LV+ +L+CK++DFGL+RVIED+ YT
Sbjct: 324 IDFSAQIAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNE---YTARE 380
Query: 795 GGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYR 854
G K P++WTAPEAI + FT SDVWS+GI+++E+++YG+ PY +N DV+ A+ +GYR
Sbjct: 381 GAKFPIKWTAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYR 440
Query: 855 LPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILD 891
+P +CP L+ +M CW+++ ERP F+ + +LD
Sbjct: 441 MPRVENCPDELYDIMKMCWKEKAEERPTFDYLQSVLD 477
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.413
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,348,618
Number of Sequences: 37866
Number of extensions: 1821911
Number of successful extensions: 9851
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 627
Number of HSP's successfully gapped in prelim test: 358
Number of HSP's that attempted gapping in prelim test: 5987
Number of HSP's gapped (non-prelim): 2375
length of query: 998
length of database: 18,247,518
effective HSP length: 112
effective length of query: 886
effective length of database: 14,006,526
effective search space: 12409782036
effective search space used: 12409782036
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.