Guide to the Human Genome
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Search of human proteins with 4758248

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4758248 ephrin-B1 precursor [Homo sapiens]
         (346 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4758248 ephrin-B1 precursor [Homo sapiens]                         707   0.0  
gi|4758250 ephrin B2 [Homo sapiens]                                   363   e-100
gi|4503489 ephrin-B3 precursor [Homo sapiens]                         238   6e-63
gi|33359680 ephrin A1 isoform b precursor [Homo sapiens]               71   2e-12
gi|33359682 ephrin A1 isoform a precursor [Homo sapiens]               70   3e-12
gi|27894381 ephrin-A2 precursor [Homo sapiens]                         63   3e-10
gi|4503487 ephrin-A5 [Homo sapiens]                                    59   5e-09
gi|33359686 ephrin A4 isoform b [Homo sapiens]                         54   3e-07
gi|4885197 ephrin A4 isoform a [Homo sapiens]                          53   5e-07
gi|100913200 ephrin A4 isoform c [Homo sapiens]                        52   6e-07
gi|4826708 ephrin A3 [Homo sapiens]                                    52   8e-07
gi|86793109 complement receptor 1 isoform S precursor [Homo sapi...    35   0.099
gi|86793036 complement receptor 1 isoform F precursor [Homo sapi...    35   0.099
gi|125661043 leukocyte immunoglobulin-like receptor, subfamily B...    35   0.099
gi|125661045 leukocyte immunoglobulin-like receptor, subfamily B...    35   0.099
gi|21450717 sushi domain containing 3 [Homo sapiens]                   35   0.13 
gi|238624188 diffuse panbronchiolitis critical region 1 protein ...    33   0.29 
gi|21735552 mitogen-activated protein kinase kinase kinase 12 [H...    33   0.38 
gi|119943125 G protein-coupled receptor 64 isoform 3 [Homo sapiens]    33   0.49 
gi|119943116 G protein-coupled receptor 64 isoform 2 [Homo sapiens]    33   0.49 
gi|119943120 G protein-coupled receptor 64 isoform 1 [Homo sapiens]    33   0.49 
gi|119943129 G protein-coupled receptor 64 isoform 4 [Homo sapiens]    33   0.49 
gi|40548378 syndecan 2 precursor [Homo sapiens]                        32   1.1  
gi|239743055 PREDICTED: hypothetical protein XP_002342730 [Homo ...    32   1.1  
gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo sapi...    32   1.1  
gi|31652242 transcription factor 20 isoform 2 [Homo sapiens]           31   1.4  
gi|31652244 transcription factor 20 isoform 1 [Homo sapiens]           31   1.4  
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f...    31   1.9  
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e...    31   1.9  
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d...    31   1.9  

>gi|4758248 ephrin-B1 precursor [Homo sapiens]
          Length = 346

 Score =  707 bits (1825), Expect = 0.0
 Identities = 346/346 (100%), Positives = 346/346 (100%)

Query: 1   MARPGQRWLGKWLVAMVVWALCRLATPLAKNLEPVSWSSLNPKFLSGKGLVIYPKIGDKL 60
           MARPGQRWLGKWLVAMVVWALCRLATPLAKNLEPVSWSSLNPKFLSGKGLVIYPKIGDKL
Sbjct: 1   MARPGQRWLGKWLVAMVVWALCRLATPLAKNLEPVSWSSLNPKFLSGKGLVIYPKIGDKL 60

Query: 61  DIICPRAEAGRPYEYYKLYLVRPEQAAACSTVLDPNVLVTCNRPEQEIRFTIKFQEFSPN 120
           DIICPRAEAGRPYEYYKLYLVRPEQAAACSTVLDPNVLVTCNRPEQEIRFTIKFQEFSPN
Sbjct: 61  DIICPRAEAGRPYEYYKLYLVRPEQAAACSTVLDPNVLVTCNRPEQEIRFTIKFQEFSPN 120

Query: 121 YMGLEFKKHHDYYITSTSNGSLEGLENREGGVCRTRTMKIIMKVGQDPNAVTPEQLTTSR 180
           YMGLEFKKHHDYYITSTSNGSLEGLENREGGVCRTRTMKIIMKVGQDPNAVTPEQLTTSR
Sbjct: 121 YMGLEFKKHHDYYITSTSNGSLEGLENREGGVCRTRTMKIIMKVGQDPNAVTPEQLTTSR 180

Query: 181 PSKEADNTVKMATQAPGSRGSLGDSDGKHETVNQEEKSGPGASGGSSGDPDGFFNSKVAL 240
           PSKEADNTVKMATQAPGSRGSLGDSDGKHETVNQEEKSGPGASGGSSGDPDGFFNSKVAL
Sbjct: 181 PSKEADNTVKMATQAPGSRGSLGDSDGKHETVNQEEKSGPGASGGSSGDPDGFFNSKVAL 240

Query: 241 FAAVGAGCVIFLLIIIFLTVLLLKLRKRHRKHTQQRAAALSLSTLASPKGGSGTAGTEPS 300
           FAAVGAGCVIFLLIIIFLTVLLLKLRKRHRKHTQQRAAALSLSTLASPKGGSGTAGTEPS
Sbjct: 241 FAAVGAGCVIFLLIIIFLTVLLLKLRKRHRKHTQQRAAALSLSTLASPKGGSGTAGTEPS 300

Query: 301 DIIIPLRTTENNYCPHYEKVSGDYGHPVYIVQEMPPQSPANIYYKV 346
           DIIIPLRTTENNYCPHYEKVSGDYGHPVYIVQEMPPQSPANIYYKV
Sbjct: 301 DIIIPLRTTENNYCPHYEKVSGDYGHPVYIVQEMPPQSPANIYYKV 346


>gi|4758250 ephrin B2 [Homo sapiens]
          Length = 333

 Score =  363 bits (932), Expect = e-100
 Identities = 191/343 (55%), Positives = 238/343 (69%), Gaps = 22/343 (6%)

Query: 8   WLGKWLVAMVVWALCRLATPLAKNLEPVSWSSLNPKFLSGKGLVIYPKIGDKLDIICPRA 67
           W   W V MV   LCR A   +  LEP+ W+S N KFL G+GLV+YP+IGDKLDIICP+ 
Sbjct: 9   WKYCWGVLMV---LCRTAISKSIVLEPIYWNSSNSKFLPGQGLVLYPQIGDKLDIICPKV 65

Query: 68  EAGR--PYEYYKLYLVRPEQAAACSTVLDPNVLVTCNRPEQEIRFTIKFQEFSPNYMGLE 125
           ++     YEYYK+Y+V  +QA  C+   +   L+ C +P+Q+I+FTIKFQEFSPN  GLE
Sbjct: 66  DSKTVGQYEYYKVYMVDKDQADRCTIKKENTPLLNCAKPDQDIKFTIKFQEFSPNLWGLE 125

Query: 126 FKKHHDYYITSTSNGSLEGLENREGGVCRTRTMKIIMKVGQDPNAV--TPEQLTTSRPSK 183
           F+K+ DYYI STSNGSLEGL+N+EGGVC+TR MKI+MKVGQD ++   T  +  T RP  
Sbjct: 126 FQKNKDYYIISTSNGSLEGLDNQEGGVCQTRAMKILMKVGQDASSAGSTRNKDPTRRPEL 185

Query: 184 EADNTVKMATQAPGSRGSLGDSDGKHETVNQEEKSGPGASGGSSGDPDGFFNSKVALFAA 243
           EA    + +T +P  + + G S               G S G SG+      S+VALFA 
Sbjct: 186 EAGTNGRSSTTSPFVKPNPGSSTD-------------GNSAGHSGN--NILGSEVALFAG 230

Query: 244 VGAGCVIFLLIIIFLTVLLLKLRKRHRKHTQQRAAALSLSTLASPKGGSGTAGTEPSDII 303
           + +GC+IF++III L VLLLK R+RHRKH+ Q    LSLSTLA+PK      G+EPSDII
Sbjct: 231 IASGCIIFIVIIITLVVLLLKYRRRHRKHSPQHTTTLSLSTLATPKRSGNNNGSEPSDII 290

Query: 304 IPLRTTENNYCPHYEKVSGDYGHPVYIVQEMPPQSPANIYYKV 346
           IPLRT ++ +CPHYEKVSGDYGHPVYIVQEMPPQSPANIYYKV
Sbjct: 291 IPLRTADSVFCPHYEKVSGDYGHPVYIVQEMPPQSPANIYYKV 333


>gi|4503489 ephrin-B3 precursor [Homo sapiens]
          Length = 340

 Score =  238 bits (607), Expect = 6e-63
 Identities = 136/329 (41%), Positives = 180/329 (54%), Gaps = 30/329 (9%)

Query: 31  NLEPVSWSSLNPKFLSGKGLVIYPKIGDKLDIICPRAEAGRP-----YEYYKLYLVRPEQ 85
           +LEPV W+S N +F +  G V+YP+IGD+LD++CPRA    P     YE+YKLYLV   Q
Sbjct: 29  SLEPVYWNSANKRFQAEGGYVLYPQIGDRLDLLCPRARPPGPHSSPNYEFYKLYLVGGAQ 88

Query: 86  AAACSTVLDPNVLVTCNRPEQEIRFTIKFQEFSPNYMGLEFKKHHDYYITSTSNGSLEGL 145
              C     PN+L+TC+RP+ ++RFTIKFQE+SPN  G EF+ HHDYYI +TS+G+ EGL
Sbjct: 89  GRRCEAPPAPNLLLTCDRPDLDLRFTIKFQEYSPNLWGHEFRSHHDYYIIATSDGTREGL 148

Query: 146 ENREGGVCRTRTMKIIMKVGQDPNAVTPEQLTTSRPSKEADNTVKMATQAPGSRGSLGDS 205
           E+ +GGVC TR MK++++VGQ P      +   S    E D     + + PG     GD 
Sbjct: 149 ESLQGGVCLTRGMKVLLRVGQSPRGGAVPRKPVSEMPMERDRGAAHSLE-PGKENLPGDP 207

Query: 206 DGKHETVNQEEKSGPGASGGSSGDPDGFFNSKVALFAAVGAGCVIFLLIIIFLTVLLLKL 265
                +   E    P +    +G   G     + +  A GA C                 
Sbjct: 208 TSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMC----------------W 251

Query: 266 RKRHRKHTQQR-----AAALSLSTLASPKGGSGTAGTEPSDIIIPLR---TTENNYCPHY 317
           R+R  K ++ R     +     S      GG G    EP ++ I LR     +  +CPHY
Sbjct: 252 RRRRAKPSESRHPGPGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGGGAADPPFCPHY 311

Query: 318 EKVSGDYGHPVYIVQEMPPQSPANIYYKV 346
           EKVSGDYGHPVYIVQ+ PPQSP NIYYKV
Sbjct: 312 EKVSGDYGHPVYIVQDGPPQSPPNIYYKV 340


>gi|33359680 ephrin A1 isoform b precursor [Homo sapiens]
          Length = 183

 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 49/135 (36%), Positives = 68/135 (50%), Gaps = 11/135 (8%)

Query: 11  KWLVAMVVWALCRLATPLAKNLEPVSWSSLNPKFLSGKGLVIYPKIGDKLDIICPRAE-- 68
           ++L A ++   C LA   A +   V W+S NPKF + +   I+ ++ D +DIICP  E  
Sbjct: 2   EFLWAPLLGLCCSLA---AADRHTVFWNSSNPKFRN-EDYTIHVQLNDYVDIICPHYEDH 57

Query: 69  --AGRPYEYYKLYLVRPEQAAACSTVLDPNVLVTCNRPEQEI---RFTIKFQEFSPNYMG 123
             A    E Y LYLV  E+   C       V   CNRP  +    + + KFQ F+P  +G
Sbjct: 58  SVADAAMEQYILYLVEHEEYQLCQPQSKDQVRWQCNRPSAKHGPEKLSEKFQRFTPFTLG 117

Query: 124 LEFKKHHDYYITSTS 138
            EFK+ H YY  S S
Sbjct: 118 KEFKEGHSYYYISHS 132


>gi|33359682 ephrin A1 isoform a precursor [Homo sapiens]
          Length = 205

 Score = 70.1 bits (170), Expect = 3e-12
 Identities = 48/133 (36%), Positives = 67/133 (50%), Gaps = 11/133 (8%)

Query: 11  KWLVAMVVWALCRLATPLAKNLEPVSWSSLNPKFLSGKGLVIYPKIGDKLDIICPRAE-- 68
           ++L A ++   C LA   A +   V W+S NPKF + +   I+ ++ D +DIICP  E  
Sbjct: 2   EFLWAPLLGLCCSLA---AADRHTVFWNSSNPKFRN-EDYTIHVQLNDYVDIICPHYEDH 57

Query: 69  --AGRPYEYYKLYLVRPEQAAACSTVLDPNVLVTCNRPEQEI---RFTIKFQEFSPNYMG 123
             A    E Y LYLV  E+   C       V   CNRP  +    + + KFQ F+P  +G
Sbjct: 58  SVADAAMEQYILYLVEHEEYQLCQPQSKDQVRWQCNRPSAKHGPEKLSEKFQRFTPFTLG 117

Query: 124 LEFKKHHDYYITS 136
            EFK+ H YY  S
Sbjct: 118 KEFKEGHSYYYIS 130


>gi|27894381 ephrin-A2 precursor [Homo sapiens]
          Length = 213

 Score = 63.2 bits (152), Expect = 3e-10
 Identities = 41/116 (35%), Positives = 56/116 (48%), Gaps = 12/116 (10%)

Query: 35  VSWSSLNPKFLSGKG-----LVIYPKIGDKLDIICPRAEAGRP----YEYYKLYLVRPEQ 85
           V W+  NP+F +G G       +   I D LDI CP   A  P     E+Y LY+V  E 
Sbjct: 39  VYWNRSNPRFHAGAGDDGGGYTVEVSINDYLDIYCPHYGAPLPPAERMEHYVLYMVNGEG 98

Query: 86  AAACSTVLDPNVLVTCNRPEQE---IRFTIKFQEFSPNYMGLEFKKHHDYYITSTS 138
            A+C           CNRP      ++F+ KFQ F+P  +G EF+  H+YY  S +
Sbjct: 99  HASCDHRQRGFKRWECNRPAAPGGPLKFSEKFQLFTPFSLGFEFRPGHEYYYISAT 154


>gi|4503487 ephrin-A5 [Homo sapiens]
          Length = 228

 Score = 59.3 bits (142), Expect = 5e-09
 Identities = 44/135 (32%), Positives = 64/135 (47%), Gaps = 10/135 (7%)

Query: 13  LVAMVVWALCRLATPLAKNLEP---VSWSSLNPKFLSGKGLVIYPKIGDKLDIICPRAEA 69
           LV +V+W       P +K +     V W+S NP+F  G    I   I D LD+ CP  E 
Sbjct: 9   LVFLVLWMCVFSQDPGSKAVADRYAVYWNSSNPRFQRGD-YHIDVCINDYLDVFCPHYED 67

Query: 70  GRPY---EYYKLYLVRPEQAAACSTVLDPNVLVTCNRPEQE---IRFTIKFQEFSPNYMG 123
             P    E Y LY+V  +  +AC           CNRP      ++F+ KFQ F+P  +G
Sbjct: 68  SVPEDKTERYVLYMVNFDGYSACDHTSKGFKRWECNRPHSPNGPLKFSEKFQLFTPFSLG 127

Query: 124 LEFKKHHDYYITSTS 138
            EF+   +Y+  S++
Sbjct: 128 FEFRPGREYFYISSA 142


>gi|33359686 ephrin A4 isoform b [Homo sapiens]
          Length = 207

 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 47/159 (29%), Positives = 71/159 (44%), Gaps = 13/159 (8%)

Query: 13  LVAMVVWALCRLATPL---AKNLEPVSWSSLNPKFLSGKGLVIYPKIGDKLDIICPRAEA 69
           L+  V+WA   L +PL   +     V W+S NP+ L G   V+   + D LDI+CP  E 
Sbjct: 6   LLRTVLWAAF-LGSPLRGGSSLRHVVYWNSSNPRLLRGDA-VVELGLNDYLDIVCPHYEG 63

Query: 70  GRPYE---YYKLYLVRPEQAAACSTVLDPNVLV--TCNRPEQEIRFTIKFQEFSPNYMGL 124
             P E    + LY+V      +C     P       C+ P   ++F+ K Q F+P  +G 
Sbjct: 64  PGPPEGPETFALYMVDWPGYESCQAE-GPRAYKRWVCSLPFGHVQFSEKIQRFTPFSLGF 122

Query: 125 EFKKHHDYYITS--TSNGSLEGLENREGGVCRTRTMKII 161
           EF     YY  S  T   S + L  +    C+ R  +++
Sbjct: 123 EFLPGETYYYISVPTPESSGQCLRLQVSVCCKERRARVL 161


>gi|4885197 ephrin A4 isoform a [Homo sapiens]
          Length = 201

 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 49/163 (30%), Positives = 71/163 (43%), Gaps = 13/163 (7%)

Query: 13  LVAMVVWALCRLATPL---AKNLEPVSWSSLNPKFLSGKGLVIYPKIGDKLDIICPRAEA 69
           L+  V+WA   L +PL   +     V W+S NP+ L G   V+   + D LDI+CP  E 
Sbjct: 6   LLRTVLWAAF-LGSPLRGGSSLRHVVYWNSSNPRLLRGDA-VVELGLNDYLDIVCPHYEG 63

Query: 70  GRPYE---YYKLYLVRPEQAAACSTVLDPNVLV--TCNRPEQEIRFTIKFQEFSPNYMGL 124
             P E    + LY+V      +C     P       C+ P   ++F+ K Q F+P  +G 
Sbjct: 64  PGPPEGPETFALYMVDWPGYESCQAE-GPRAYKRWVCSLPFGHVQFSEKIQRFTPFSLGF 122

Query: 125 EFKKHHDYYITS--TSNGSLEGLENREGGVCRTRTMKIIMKVG 165
           EF     YY  S  T   S + L  +    C+ R  +    VG
Sbjct: 123 EFLPGETYYYISVPTPESSGQCLRLQVSVCCKERKSESAHPVG 165


>gi|100913200 ephrin A4 isoform c [Homo sapiens]
          Length = 193

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 47/156 (30%), Positives = 69/156 (44%), Gaps = 13/156 (8%)

Query: 13  LVAMVVWALCRLATPL---AKNLEPVSWSSLNPKFLSGKGLVIYPKIGDKLDIICPRAEA 69
           L+  V+WA   L +PL   +     V W+S NP+ L G   V+   + D LDI+CP  E 
Sbjct: 6   LLRTVLWAAF-LGSPLRGGSSLRHVVYWNSSNPRLLRGDA-VVELGLNDYLDIVCPHYEG 63

Query: 70  GRPYE---YYKLYLVRPEQAAACSTVLDPNVLV--TCNRPEQEIRFTIKFQEFSPNYMGL 124
             P E    + LY+V      +C     P       C+ P   ++F+ K Q F+P  +G 
Sbjct: 64  PGPPEGPETFALYMVDWPGYESCQAE-GPRAYKRWVCSLPFGHVQFSEKIQRFTPFSLGF 122

Query: 125 EFKKHHDYYITS--TSNGSLEGLENREGGVCRTRTM 158
           EF     YY  S  T   S + L  +    C+ R +
Sbjct: 123 EFLPGETYYYISVPTPESSGQCLRLQVSVCCKERNL 158


>gi|4826708 ephrin A3 [Homo sapiens]
          Length = 238

 Score = 52.0 bits (123), Expect = 8e-07
 Identities = 55/208 (26%), Positives = 81/208 (38%), Gaps = 37/208 (17%)

Query: 31  NLEPVSWSSLNPKFLSGKGLVIYPKIGDKLDIICPRAEA-----------GRPYEYYKLY 79
           N   V W+S N + L  +G  +   + D LDI CP   +           G   E Y LY
Sbjct: 31  NRHAVYWNSSN-QHLRREGYTVQVNVNDYLDIYCPHYNSSGVGPGAGPGPGGGAEQYVLY 89

Query: 80  LVRPEQAAACSTVLDPNVLVTCNRPE---QEIRFTIKFQEFSPNYMGLEFKKHHDYYITS 136
           +V       C+          CNRP      I+F+ KFQ +S   +G EF   H+YY  S
Sbjct: 90  MVSRNGYRTCNASQGFKRW-ECNRPHAPHSPIKFSEKFQRYSAFSLGYEFHAGHEYYYIS 148

Query: 137 TSNGSLEGLENREGGVCRTRTMKIIMKVGQDPNAVTPEQLTTSRPSKEADNTVKMATQAP 196
           T   +L           +   MK+ +              +TS   ++   T+   T  P
Sbjct: 149 TPTHNLH---------WKCLRMKVFVCCA-----------STSHSGEKPVPTLPQFTMGP 188

Query: 197 GSR-GSLGDSDGKHETVNQEEKSGPGAS 223
             +   L D +G++  V + EKS  G S
Sbjct: 189 NVKINVLEDFEGENPQVPKLEKSISGTS 216


>gi|86793109 complement receptor 1 isoform S precursor [Homo sapiens]
          Length = 2489

 Score = 35.0 bits (79), Expect = 0.099
 Identities = 19/54 (35%), Positives = 31/54 (57%), Gaps = 4/54 (7%)

Query: 239  ALFAAVGAGCVIFLLIIIFLTVLLLKLRKRHRKHTQQRAAALSLSTLASPKGGS 292
            AL     +G + F+L+IIFL+ ++LK RK +  H   +  A+ L +    +GGS
Sbjct: 2422 ALIVGTLSGTIFFILLIIFLSWIILKHRKGNNAHENPKEVAIHLHS----QGGS 2471


>gi|86793036 complement receptor 1 isoform F precursor [Homo sapiens]
          Length = 2039

 Score = 35.0 bits (79), Expect = 0.099
 Identities = 19/54 (35%), Positives = 31/54 (57%), Gaps = 4/54 (7%)

Query: 239  ALFAAVGAGCVIFLLIIIFLTVLLLKLRKRHRKHTQQRAAALSLSTLASPKGGS 292
            AL     +G + F+L+IIFL+ ++LK RK +  H   +  A+ L +    +GGS
Sbjct: 1972 ALIVGTLSGTIFFILLIIFLSWIILKHRKGNNAHENPKEVAIHLHS----QGGS 2021


>gi|125661043 leukocyte immunoglobulin-like receptor, subfamily B,
           member 3 isoform 1 [Homo sapiens]
          Length = 632

 Score = 35.0 bits (79), Expect = 0.099
 Identities = 27/82 (32%), Positives = 41/82 (50%), Gaps = 7/82 (8%)

Query: 221 GASGGSSGDPDGFFNSK-VALFAAVGAGCVIFLLIIIFLTVLLLKLRKRHRKHTQQRAAA 279
           G SGGSS  P G  ++  +  +  V  G  +  ++++FL + LL  R+RH KH   R + 
Sbjct: 420 GHSGGSSLPPTGPPSTPGLGRYLEVLIGVSVAFVLLLFLLLFLLLRRQRHSKH---RTSD 476

Query: 280 LSLSTLASPKGGSGTAGTEPSD 301
              +    P   +G A TEP D
Sbjct: 477 QRKTDFQRP---AGAAETEPKD 495


>gi|125661045 leukocyte immunoglobulin-like receptor, subfamily B,
           member 3 isoform 2 [Homo sapiens]
          Length = 631

 Score = 35.0 bits (79), Expect = 0.099
 Identities = 27/82 (32%), Positives = 41/82 (50%), Gaps = 7/82 (8%)

Query: 221 GASGGSSGDPDGFFNSK-VALFAAVGAGCVIFLLIIIFLTVLLLKLRKRHRKHTQQRAAA 279
           G SGGSS  P G  ++  +  +  V  G  +  ++++FL + LL  R+RH KH   R + 
Sbjct: 420 GHSGGSSLPPTGPPSTPGLGRYLEVLIGVSVAFVLLLFLLLFLLLRRQRHSKH---RTSD 476

Query: 280 LSLSTLASPKGGSGTAGTEPSD 301
              +    P   +G A TEP D
Sbjct: 477 QRKTDFQRP---AGAAETEPKD 495


>gi|21450717 sushi domain containing 3 [Homo sapiens]
          Length = 255

 Score = 34.7 bits (78), Expect = 0.13
 Identities = 18/51 (35%), Positives = 29/51 (56%)

Query: 230 PDGFFNSKVALFAAVGAGCVIFLLIIIFLTVLLLKLRKRHRKHTQQRAAAL 280
           P   F  KVA+ A++ +  +I L+ + FLT  LLK  K+ ++    R+A L
Sbjct: 96  PHETFGFKVAVIASIVSCAIILLMSMAFLTCCLLKCVKKSKRRRSNRSAQL 146


>gi|238624188 diffuse panbronchiolitis critical region 1 protein [Homo
            sapiens]
          Length = 1393

 Score = 33.5 bits (75), Expect = 0.29
 Identities = 36/156 (23%), Positives = 62/156 (39%), Gaps = 21/156 (13%)

Query: 135  TSTSNGSLEGLENREGGVCRTRTMKIIMKVGQDPNAVTPEQLTTSRPSKEADNTVKMATQ 194
            T T    ++  EN E     T+T+K  +KV  D +  T    T+S  +K      ++  Q
Sbjct: 1219 TETIKAPVKSTENPEKTAAVTKTIKPSVKVTGDKSLTT----TSSHLNK-----TEVTHQ 1269

Query: 195  APGSRGSLGDSDGKHETVNQE------------EKSGPGASGGSSGDPDGFFNSKVALFA 242
             P    +L  S  K  ++  E            + S  G   G  G+ D F    + +  
Sbjct: 1270 VPTGSFTLITSRTKLSSITSEATGNESHPYLNKDGSQKGIHAGQMGENDSFPAWAIVIVV 1329

Query: 243  AVGAGCVIFLLIIIFLTVLLLKLRKRHRKHTQQRAA 278
             V    ++  L +IFL   +++ R+   ++TQ   A
Sbjct: 1330 LVAVILLLVFLGLIFLVSYMMRTRRTLTQNTQYNDA 1365


>gi|21735552 mitogen-activated protein kinase kinase kinase 12 [Homo
           sapiens]
          Length = 859

 Score = 33.1 bits (74), Expect = 0.38
 Identities = 17/53 (32%), Positives = 22/53 (41%)

Query: 181 PSKEADNTVKMATQAPGSRGSLGDSDGKHETVNQEEKSGPGASGGSSGDPDGF 233
           PS       K   +   ++GS GD  G    V   E  GPG+ GG  G P  +
Sbjct: 535 PSPGRSRRGKTRHRKASAKGSCGDLPGLRTAVPPHEPGGPGSPGGLGGGPSAW 587


>gi|119943125 G protein-coupled receptor 64 isoform 3 [Homo sapiens]
          Length = 995

 Score = 32.7 bits (73), Expect = 0.49
 Identities = 22/66 (33%), Positives = 37/66 (56%), Gaps = 6/66 (9%)

Query: 227 SGDPDGFF---NSKVALFAAVGAGCVIFLL-IIIFLTVL--LLKLRKRHRKHTQQRAAAL 280
           +G PD F    N+ V     VG  CVIFLL + +F+ VL  L +++K+ +   Q++ +  
Sbjct: 749 NGSPDDFCWINNNAVFYITVVGYFCVIFLLNVSMFIVVLVQLCRIKKKKQLGAQRKTSIQ 808

Query: 281 SLSTLA 286
            L ++A
Sbjct: 809 DLRSIA 814


>gi|119943116 G protein-coupled receptor 64 isoform 2 [Homo sapiens]
          Length = 1003

 Score = 32.7 bits (73), Expect = 0.49
 Identities = 22/66 (33%), Positives = 37/66 (56%), Gaps = 6/66 (9%)

Query: 227 SGDPDGFF---NSKVALFAAVGAGCVIFLL-IIIFLTVL--LLKLRKRHRKHTQQRAAAL 280
           +G PD F    N+ V     VG  CVIFLL + +F+ VL  L +++K+ +   Q++ +  
Sbjct: 757 NGSPDDFCWINNNAVFYITVVGYFCVIFLLNVSMFIVVLVQLCRIKKKKQLGAQRKTSIQ 816

Query: 281 SLSTLA 286
            L ++A
Sbjct: 817 DLRSIA 822


>gi|119943120 G protein-coupled receptor 64 isoform 1 [Homo sapiens]
          Length = 1017

 Score = 32.7 bits (73), Expect = 0.49
 Identities = 22/66 (33%), Positives = 37/66 (56%), Gaps = 6/66 (9%)

Query: 227 SGDPDGFF---NSKVALFAAVGAGCVIFLL-IIIFLTVL--LLKLRKRHRKHTQQRAAAL 280
           +G PD F    N+ V     VG  CVIFLL + +F+ VL  L +++K+ +   Q++ +  
Sbjct: 771 NGSPDDFCWINNNAVFYITVVGYFCVIFLLNVSMFIVVLVQLCRIKKKKQLGAQRKTSIQ 830

Query: 281 SLSTLA 286
            L ++A
Sbjct: 831 DLRSIA 836


>gi|119943129 G protein-coupled receptor 64 isoform 4 [Homo sapiens]
          Length = 1014

 Score = 32.7 bits (73), Expect = 0.49
 Identities = 22/66 (33%), Positives = 37/66 (56%), Gaps = 6/66 (9%)

Query: 227 SGDPDGFF---NSKVALFAAVGAGCVIFLL-IIIFLTVL--LLKLRKRHRKHTQQRAAAL 280
           +G PD F    N+ V     VG  CVIFLL + +F+ VL  L +++K+ +   Q++ +  
Sbjct: 768 NGSPDDFCWINNNAVFYITVVGYFCVIFLLNVSMFIVVLVQLCRIKKKKQLGAQRKTSIQ 827

Query: 281 SLSTLA 286
            L ++A
Sbjct: 828 DLRSIA 833


>gi|40548378 syndecan 2 precursor [Homo sapiens]
          Length = 201

 Score = 31.6 bits (70), Expect = 1.1
 Identities = 33/118 (27%), Positives = 55/118 (46%), Gaps = 15/118 (12%)

Query: 165 GQDPNAVTPEQLTTSRP----------SKEADNTVKMATQAPGSRGSLGDSDGKHETVNQ 214
           G D +  +PE LTTSRP           K    T+ +  + P    S  ++D +   ++ 
Sbjct: 58  GADEDVESPE-LTTSRPLPKILLTSAAPKVETTTLNIQNKIPAQTKSPEETDKEKVHLSD 116

Query: 215 EEKSGPGASGGSSGDPDGFFNS---KVALFAAVGAGCVIFLLIIIFLTVLLL-KLRKR 268
            E+    A   ++   +   +S   +  + AAV AG VI  L  IFL +LL+ ++RK+
Sbjct: 117 SERKMDPAEEDTNVYTEKHSDSLFKRTEVLAAVIAGGVIGFLFAIFLILLLVYRMRKK 174


>gi|239743055 PREDICTED: hypothetical protein XP_002342730 [Homo
           sapiens]
          Length = 235

 Score = 31.6 bits (70), Expect = 1.1
 Identities = 21/77 (27%), Positives = 35/77 (45%), Gaps = 9/77 (11%)

Query: 90  STVLDPNVLVTCNRPEQEIRFTIKFQEFSPNYMGLEF-----KKHHDYYITSTSNGSL-- 142
           S  L P    TC+ P   +R  +  Q        L F     ++ H+++++S+S  S   
Sbjct: 40  SITLSPRQEGTCSSPPAPLRPELPSQSHPEYLKALGFPRLLPQRSHEHHVSSSSKSSACG 99

Query: 143 --EGLENREGGVCRTRT 157
              G+   +G +CRTRT
Sbjct: 100 AGPGVGAAKGALCRTRT 116


>gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo
           sapiens]
          Length = 950

 Score = 31.6 bits (70), Expect = 1.1
 Identities = 28/96 (29%), Positives = 43/96 (44%), Gaps = 10/96 (10%)

Query: 134 ITSTSNGSLEGLENREGGVC----RTRTMKIIMKVGQDPNAVTPEQLTTSRPSKEADNTV 189
           + S++ GS    + R   VC    + +T  +    G  P A + E+  T  PS  +D+T 
Sbjct: 740 VCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCAGSTER--TGEPSASSDSTG 797

Query: 190 KMATQAPGSRGSLGDSDGKHETVNQEE----KSGPG 221
           K     P  R S     G H +V+ EE    ++GPG
Sbjct: 798 KPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPG 833


>gi|31652242 transcription factor 20 isoform 2 [Homo sapiens]
          Length = 1938

 Score = 31.2 bits (69), Expect = 1.4
 Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 7/71 (9%)

Query: 165 GQDPNAVTPEQLTTSRP-----SKEADNTVKMATQAPGSRGSLGDSDGKHETVNQEEKSG 219
           GQD  +   +   T RP     +KE  +      + PG  GS G+ +G + + +  E  G
Sbjct: 622 GQDKGSQEDDPAATQRPPSNGGAKETSHASLPQPEPPGGGGSKGNKNGDNNSNHNGE--G 679

Query: 220 PGASGGSSGDP 230
            G SG S+  P
Sbjct: 680 NGQSGHSAAGP 690



 Score = 29.6 bits (65), Expect = 4.1
 Identities = 18/64 (28%), Positives = 26/64 (40%), Gaps = 1/64 (1%)

Query: 168  PNAVTPEQLTTSRPSKEADNTVKMATQAPGSR-GSLGDSDGKHETVNQEEKSGPGASGGS 226
            P A T + L+   P       ++      G R G  G S  ++    ++ K  PG S G 
Sbjct: 967  PGAATHDSLSDYGPQDSRPTPMRRVPGRVGGREGMRGRSPSQYHDFAEKLKMSPGRSRGP 1026

Query: 227  SGDP 230
             GDP
Sbjct: 1027 GGDP 1030


>gi|31652244 transcription factor 20 isoform 1 [Homo sapiens]
          Length = 1960

 Score = 31.2 bits (69), Expect = 1.4
 Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 7/71 (9%)

Query: 165 GQDPNAVTPEQLTTSRP-----SKEADNTVKMATQAPGSRGSLGDSDGKHETVNQEEKSG 219
           GQD  +   +   T RP     +KE  +      + PG  GS G+ +G + + +  E  G
Sbjct: 622 GQDKGSQEDDPAATQRPPSNGGAKETSHASLPQPEPPGGGGSKGNKNGDNNSNHNGE--G 679

Query: 220 PGASGGSSGDP 230
            G SG S+  P
Sbjct: 680 NGQSGHSAAGP 690



 Score = 29.6 bits (65), Expect = 4.1
 Identities = 18/64 (28%), Positives = 26/64 (40%), Gaps = 1/64 (1%)

Query: 168  PNAVTPEQLTTSRPSKEADNTVKMATQAPGSR-GSLGDSDGKHETVNQEEKSGPGASGGS 226
            P A T + L+   P       ++      G R G  G S  ++    ++ K  PG S G 
Sbjct: 967  PGAATHDSLSDYGPQDSRPTPMRRVPGRVGGREGMRGRSPSQYHDFAEKLKMSPGRSRGP 1026

Query: 227  SGDP 230
             GDP
Sbjct: 1027 GGDP 1030


>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
            [Homo sapiens]
          Length = 1412

 Score = 30.8 bits (68), Expect = 1.9
 Identities = 25/106 (23%), Positives = 43/106 (40%), Gaps = 9/106 (8%)

Query: 134  ITSTSNGSLEGLENREGGV------CRTRTMKIIMKVGQDPN---AVTPEQLTTSRPSKE 184
            + +T   S +G E+R+  +       RT   K   K+G       +V+PE+ +T+   K 
Sbjct: 1255 VDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKA 1314

Query: 185  ADNTVKMATQAPGSRGSLGDSDGKHETVNQEEKSGPGASGGSSGDP 230
              +      +    +GSLG    K E   + +K      GG   +P
Sbjct: 1315 KRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNP 1360


>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
            [Homo sapiens]
          Length = 1451

 Score = 30.8 bits (68), Expect = 1.9
 Identities = 25/106 (23%), Positives = 43/106 (40%), Gaps = 9/106 (8%)

Query: 134  ITSTSNGSLEGLENREGGV------CRTRTMKIIMKVGQDPN---AVTPEQLTTSRPSKE 184
            + +T   S +G E+R+  +       RT   K   K+G       +V+PE+ +T+   K 
Sbjct: 1294 VDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKA 1353

Query: 185  ADNTVKMATQAPGSRGSLGDSDGKHETVNQEEKSGPGASGGSSGDP 230
              +      +    +GSLG    K E   + +K      GG   +P
Sbjct: 1354 KRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNP 1399


>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
            [Homo sapiens]
          Length = 1488

 Score = 30.8 bits (68), Expect = 1.9
 Identities = 25/106 (23%), Positives = 43/106 (40%), Gaps = 9/106 (8%)

Query: 134  ITSTSNGSLEGLENREGGV------CRTRTMKIIMKVGQDPN---AVTPEQLTTSRPSKE 184
            + +T   S +G E+R+  +       RT   K   K+G       +V+PE+ +T+   K 
Sbjct: 1331 VDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKA 1390

Query: 185  ADNTVKMATQAPGSRGSLGDSDGKHETVNQEEKSGPGASGGSSGDP 230
              +      +    +GSLG    K E   + +K      GG   +P
Sbjct: 1391 KRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNP 1436


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.135    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,227,339
Number of Sequences: 37866
Number of extensions: 710498
Number of successful extensions: 2807
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 31
Number of HSP's that attempted gapping in prelim test: 2728
Number of HSP's gapped (non-prelim): 81
length of query: 346
length of database: 18,247,518
effective HSP length: 103
effective length of query: 243
effective length of database: 14,347,320
effective search space: 3486398760
effective search space used: 3486398760
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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