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Search of human proteins with 4758010
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4758010 clock [Homo sapiens]
(846 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4758010 clock [Homo sapiens] 1680 0.0
gi|22027471 neuronal PAS domain protein 2 [Homo sapiens] 748 0.0
gi|71852582 aryl hydrocarbon receptor nuclear translocator-like ... 161 3e-39
gi|71852580 aryl hydrocarbon receptor nuclear translocator-like ... 161 3e-39
gi|42716311 aryl hydrocarbon receptor nuclear translocator-like ... 161 3e-39
gi|31745180 aryl hydrocarbon receptor nuclear translocator-like ... 144 3e-34
gi|40254439 endothelial PAS domain protein 1 [Homo sapiens] 138 2e-32
gi|30795242 aryl hydrocarbon receptor nuclear translocator isofo... 130 7e-30
gi|4502231 aryl hydrocarbon receptor nuclear translocator isofor... 130 7e-30
gi|31077211 hypoxia-inducible factor 1, alpha subunit isoform 2 ... 129 1e-29
gi|4504385 hypoxia-inducible factor 1, alpha subunit isoform 1 [... 129 1e-29
gi|90421311 hypoxia inducible factor 3, alpha subunit isoform c ... 117 4e-26
gi|23065535 hypoxia inducible factor 3, alpha subunit isoform a ... 117 6e-26
gi|21614542 single-minded homolog 1 [Homo sapiens] 113 6e-25
gi|68303555 aryl hydrocarbon receptor nuclear translocator 2 [Ho... 110 5e-24
gi|4827004 single-minded homolog 2 long isoform [Homo sapiens] 105 2e-22
gi|194239684 single-minded homolog 2 short isoform [Homo sapiens] 105 2e-22
gi|90421316 hypoxia inducible factor 3, alpha subunit isoform b ... 103 9e-22
gi|157785548 PAS domain containing 1 [Homo sapiens] 102 2e-21
gi|4502003 aryl hydrocarbon receptor [Homo sapiens] 99 2e-20
gi|5729858 nuclear receptor coactivator 2 [Homo sapiens] 90 1e-17
gi|11545847 neuronal PAS domain protein 3 isoform 1 [Homo sapiens] 88 3e-17
gi|22538457 nuclear receptor coactivator 1 isoform 2 [Homo sapiens] 84 4e-16
gi|22538459 nuclear receptor coactivator 1 isoform 3 [Homo sapiens] 84 4e-16
gi|22538455 nuclear receptor coactivator 1 isoform 1 [Homo sapiens] 84 4e-16
gi|41281831 neuronal PAS domain protein 3 isoform 2 [Homo sapiens] 84 7e-16
gi|22027482 neuronal PAS domain protein 1 [Homo sapiens] 80 6e-15
gi|32307126 nuclear receptor coactivator 3 isoform a [Homo sapiens] 79 2e-14
gi|32307124 nuclear receptor coactivator 3 isoform b [Homo sapiens] 79 2e-14
gi|30795240 aryl hydrocarbon receptor nuclear translocator isofo... 74 7e-13
>gi|4758010 clock [Homo sapiens]
Length = 846
Score = 1680 bits (4351), Expect = 0.0
Identities = 846/846 (100%), Positives = 846/846 (100%)
Query: 1 MLFTVSCSKMSSIVDRDDSSIFDGLVEEDDKDKAKRVSRNKSEKKRRDQFNVLIKELGSM 60
MLFTVSCSKMSSIVDRDDSSIFDGLVEEDDKDKAKRVSRNKSEKKRRDQFNVLIKELGSM
Sbjct: 1 MLFTVSCSKMSSIVDRDDSSIFDGLVEEDDKDKAKRVSRNKSEKKRRDQFNVLIKELGSM 60
Query: 61 LPGNARKMDKSTVLQKSIDFLRKHKEITAQSDASEIRQDWKPTFLSNEEFTQLMLEALDG 120
LPGNARKMDKSTVLQKSIDFLRKHKEITAQSDASEIRQDWKPTFLSNEEFTQLMLEALDG
Sbjct: 61 LPGNARKMDKSTVLQKSIDFLRKHKEITAQSDASEIRQDWKPTFLSNEEFTQLMLEALDG 120
Query: 121 FFLAIMTDGSIIYVSESVTSLLEHLPSDLVDQSIFNFIPEGEHSEVYKILSTHLLESDSL 180
FFLAIMTDGSIIYVSESVTSLLEHLPSDLVDQSIFNFIPEGEHSEVYKILSTHLLESDSL
Sbjct: 121 FFLAIMTDGSIIYVSESVTSLLEHLPSDLVDQSIFNFIPEGEHSEVYKILSTHLLESDSL 180
Query: 181 TPEYLKSKNQLEFCCHMLRGTIDPKEPSTYEYVKFIGNFKSLNSVSSSAHNGFEGTIQRT 240
TPEYLKSKNQLEFCCHMLRGTIDPKEPSTYEYVKFIGNFKSLNSVSSSAHNGFEGTIQRT
Sbjct: 181 TPEYLKSKNQLEFCCHMLRGTIDPKEPSTYEYVKFIGNFKSLNSVSSSAHNGFEGTIQRT 240
Query: 241 HRPSYEDRVCFVATVRLATPQFIKEMCTVEEPNEEFTSRHSLEWKFLFLDHRAPPIIGYL 300
HRPSYEDRVCFVATVRLATPQFIKEMCTVEEPNEEFTSRHSLEWKFLFLDHRAPPIIGYL
Sbjct: 241 HRPSYEDRVCFVATVRLATPQFIKEMCTVEEPNEEFTSRHSLEWKFLFLDHRAPPIIGYL 300
Query: 301 PFEVLGTSGYDYYHVDDLENLAKCHEHLMQYGKGKSCYYRFLTKGQQWIWLQTHYYITYH 360
PFEVLGTSGYDYYHVDDLENLAKCHEHLMQYGKGKSCYYRFLTKGQQWIWLQTHYYITYH
Sbjct: 301 PFEVLGTSGYDYYHVDDLENLAKCHEHLMQYGKGKSCYYRFLTKGQQWIWLQTHYYITYH 360
Query: 361 QWNSRPEFIVCTHTVVSYAEVRAERRRELGIEESLPETAADKSQDSGSDNRINTVSLKEA 420
QWNSRPEFIVCTHTVVSYAEVRAERRRELGIEESLPETAADKSQDSGSDNRINTVSLKEA
Sbjct: 361 QWNSRPEFIVCTHTVVSYAEVRAERRRELGIEESLPETAADKSQDSGSDNRINTVSLKEA 420
Query: 421 LERFDHSPTPSASSRSSRKSSHTAVSDPSSTPTKIPTDTSTPPRQHLPAHEKMVQRRSSF 480
LERFDHSPTPSASSRSSRKSSHTAVSDPSSTPTKIPTDTSTPPRQHLPAHEKMVQRRSSF
Sbjct: 421 LERFDHSPTPSASSRSSRKSSHTAVSDPSSTPTKIPTDTSTPPRQHLPAHEKMVQRRSSF 480
Query: 481 SSQSINSQSVGSSLTQPVMSQATNLPIPQGMSQFQFSAQLGAMQHLKDQLEQRTRMIEAN 540
SSQSINSQSVGSSLTQPVMSQATNLPIPQGMSQFQFSAQLGAMQHLKDQLEQRTRMIEAN
Sbjct: 481 SSQSINSQSVGSSLTQPVMSQATNLPIPQGMSQFQFSAQLGAMQHLKDQLEQRTRMIEAN 540
Query: 541 IHRQQEELRKIQEQLQMVHGQGLQMFLQQSNPGLNFGSVQLSSGNSSNIQQLAPINMQGQ 600
IHRQQEELRKIQEQLQMVHGQGLQMFLQQSNPGLNFGSVQLSSGNSSNIQQLAPINMQGQ
Sbjct: 541 IHRQQEELRKIQEQLQMVHGQGLQMFLQQSNPGLNFGSVQLSSGNSSNIQQLAPINMQGQ 600
Query: 601 VVPTNQIQSGMNTGHIGTTQHMIQQQTLQSTSTQSQQNVLSGHSQQTSLPSQTQSTLTAP 660
VVPTNQIQSGMNTGHIGTTQHMIQQQTLQSTSTQSQQNVLSGHSQQTSLPSQTQSTLTAP
Sbjct: 601 VVPTNQIQSGMNTGHIGTTQHMIQQQTLQSTSTQSQQNVLSGHSQQTSLPSQTQSTLTAP 660
Query: 661 LYNTMVISQPAAGSMVQIPSSMPQNSTQSAAVTTFTQDRQIRFSQGQQLVTKLVTAPVAC 720
LYNTMVISQPAAGSMVQIPSSMPQNSTQSAAVTTFTQDRQIRFSQGQQLVTKLVTAPVAC
Sbjct: 661 LYNTMVISQPAAGSMVQIPSSMPQNSTQSAAVTTFTQDRQIRFSQGQQLVTKLVTAPVAC 720
Query: 721 GAVMVPSTMLMGQVVTAYPTFATQQQQSQTLSVTQQQQQQSSQEQQLTSVQQPSQAQLTQ 780
GAVMVPSTMLMGQVVTAYPTFATQQQQSQTLSVTQQQQQQSSQEQQLTSVQQPSQAQLTQ
Sbjct: 721 GAVMVPSTMLMGQVVTAYPTFATQQQQSQTLSVTQQQQQQSSQEQQLTSVQQPSQAQLTQ 780
Query: 781 PPQQFLQTSRLLHGNPSTQLILSAAFPLQQSTFPQSHHQQHQSQQQQQLSRHRTDSLPDP 840
PPQQFLQTSRLLHGNPSTQLILSAAFPLQQSTFPQSHHQQHQSQQQQQLSRHRTDSLPDP
Sbjct: 781 PPQQFLQTSRLLHGNPSTQLILSAAFPLQQSTFPQSHHQQHQSQQQQQLSRHRTDSLPDP 840
Query: 841 SKVQPQ 846
SKVQPQ
Sbjct: 841 SKVQPQ 846
>gi|22027471 neuronal PAS domain protein 2 [Homo sapiens]
Length = 824
Score = 748 bits (1931), Expect = 0.0
Identities = 424/837 (50%), Positives = 545/837 (65%), Gaps = 35/837 (4%)
Query: 26 VEEDDKDKAKRVSRNKSEKKRRDQFNVLIKELGSMLPGNARKMDKSTVLQKSIDFLRKHK 85
++ED+KD+AKR SRNKSEKKRRDQFNVLIKEL SMLPGN RKMDK+TVL+K I FL+KH
Sbjct: 1 MDEDEKDRAKRASRNKSEKKRRDQFNVLIKELSSMLPGNTRKMDKTTVLEKVIGFLQKHN 60
Query: 86 EITAQSDASEIRQDWKPTFLSNEEFTQLMLEALDGFFLAIMTDGSIIYVSESVTSLLEHL 145
E++AQ++ +I+QDWKP+FLSNEEFTQLMLEALDGF +A+ TDGSIIYVS+S+T LL HL
Sbjct: 61 EVSAQTEICDIQQDWKPSFLSNEEFTQLMLEALDGFIIAVTTDGSIIYVSDSITPLLGHL 120
Query: 146 PSDLVDQSIFNFIPEGEHSEVYKILSTHLLESDSLTPEYLKSKNQLEFCCHMLRGTIDPK 205
PSD++DQ++ NF+PE EHSEVYKILS+H+L +DS +PEYLKS + LEF CH+LRG+++PK
Sbjct: 121 PSDVMDQNLLNFLPEQEHSEVYKILSSHMLVTDSPSPEYLKSDSDLEFYCHLLRGSLNPK 180
Query: 206 EPSTYEYVKFIGNFKSLNSVSSSAHNGFEGTIQRTHRPSYEDRVCFVATVRLATPQFIKE 265
E TYEY+KF+GNF+S N+V S + NGF+ T+ R R VCF+ATVRLATPQF+KE
Sbjct: 181 EFPTYEYIKFVGNFRSYNNVPSPSCNGFDNTLSRPCRVPLGKEVCFIATVRLATPQFLKE 240
Query: 266 MCTVEEPNEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHVDDLENLAKCH 325
MC V+EP EEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYH+DDLE LA+CH
Sbjct: 241 MCIVDEPLEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHIDDLELLARCH 300
Query: 326 EHLMQYGKGKSCYYRFLTKGQQWIWLQTHYYITYHQWNSRPEFIVCTHTVVSYAEVRAER 385
+HLMQ+GKGKSC YRFLTKGQQWIWLQTHYYITYHQWNS+PEFIVCTH+VVSYA+VR ER
Sbjct: 301 QHLMQFGKGKSCCYRFLTKGQQWIWLQTHYYITYHQWNSKPEFIVCTHSVVSYADVRVER 360
Query: 386 RRELGIEESLPE---TAADKSQDSGSDNRINTVSLKEALERFDHSPTPSASSRSSRKSSH 442
R+EL +E+ E ++A K + S + R + +L + S +PSASSRSS KSSH
Sbjct: 361 RQELALEDPPSEALHSSALKDKGSSLEPRQHFNTLDVGASGLNTSHSPSASSRSSHKSSH 420
Query: 443 TAVSDPSSTPTKIPTDTSTP--PRQHLPAHEKMVQRRSSFSSQSINSQSVGS-SLTQPVM 499
TA+S+P+STPTK+ + STP PR E V S ++ S S LTQ ++
Sbjct: 421 TAMSEPTSTPTKLMAEASTPALPRSATLPQELPVPGLSQAATMPAPLPSPSSCDLTQQLL 480
Query: 500 SQATNLPIPQGMSQFQFSAQLGAMQHLKDQLEQRTRMIEANIHRQQEELRKIQEQLQMVH 559
Q P M+ QFSAQ Q +KDQLEQRTR+++ANI QQEEL KIQEQL +V
Sbjct: 481 PQTVLQSTPAPMA--QFSAQFSMFQTIKDQLEQRTRILQANIRWQQEELHKIQEQLCLVQ 538
Query: 560 GQGLQMFLQQSNPGLNFGSVQLSSGNSSNIQQLAPINMQGQVVPTNQIQSGMNTGHIGTT 619
+QMFLQQ L+F S Q +QQ + Q Q+ Q+ +++ + T+
Sbjct: 539 DSNVQMFLQQPAVSLSFSSTQRPEA-QQQLQQRSAAVTQPQLGAGPQLPGQISSAQV-TS 596
Query: 620 QHMIQQQTLQSTSTQSQQNVLSGHSQQTSLPSQTQSTLTAPLYNTMVISQPAAGSMVQIP 679
QH++++ ++ STQ + + S Q+S ++ S+L +P + P+ + P
Sbjct: 597 QHLLRESSV--ISTQGPKPMRSSQLMQSS--GRSGSSLVSPFSSATAALPPSLN--LTTP 650
Query: 680 SSMPQNSTQSAAVTTFTQDRQIRFSQGQQLVTKLVTAPVACGAVMVPSTMLMG------- 732
+S Q+++Q F+ DRQ+R Q + + P +C A G
Sbjct: 651 ASTSQDASQCQPSPDFSHDRQLRLLLSQPIQPMM---PGSCDARQPSEVSRTGRQVKYAQ 707
Query: 733 -QVVTAYPTFATQQQQSQTLSVTQQQQQ--QSSQEQQLTSVQQPSQAQLTQPPQQFLQTS 789
Q V P S + V Q S S QP+QA+ QPPQ +LQ
Sbjct: 708 SQTVFQNPDAHPANSSSAPMPVLLMGQAVLHPSFPASQPSPLQPAQAR-QQPPQHYLQVQ 766
Query: 790 --RLLHGNPSTQLILSAAFPLQQSTFPQSHHQQHQSQQQQQLSRHRTDSLPDPSKVQ 844
LH L+LS + Q T + Q +Q Q R SL + S +Q
Sbjct: 767 APTSLHSEQQDSLLLS-TYSQQPGTL--GYPQPPPAQPQPLRPPRRVSSLSESSGLQ 820
>gi|71852582 aryl hydrocarbon receptor nuclear translocator-like
isoform b [Homo sapiens]
Length = 582
Score = 161 bits (407), Expect = 3e-39
Identities = 125/394 (31%), Positives = 204/394 (51%), Gaps = 38/394 (9%)
Query: 15 DRDDSSIFDGLVEEDDKDKAKRVSRNKSEKKRRDQFNVLIKELGSMLP---GNARKMDKS 71
D+DD E + K R + ++ EK+RRD+ N I EL S++P +RK+DK
Sbjct: 10 DKDDPHGRLEYTEHQGRIKNAREAHSQIEKRRRDKMNSFIDELASLVPTCNAMSRKLDKL 69
Query: 72 TVLQKSIDFLRKHKEITAQSDASEIRQDWKPTFLSNEEFTQLMLEALDGFFLAIMTD-GS 130
TVL+ ++ ++ + T + ++KPTFLS++E L+L A DGF + D G
Sbjct: 70 TVLRMAVQHMKTLRGATNPYTEA----NYKPTFLSDDELKHLILRAADGFLFVVGCDRGK 125
Query: 131 IIYVSESVTSLLEHLPSDLVDQSIFNFIPEGEHSEVYKILS--------------THLLE 176
I++VSESV +L + +DL+ QS+F+++ + ++V + LS T L
Sbjct: 126 ILFVSESVFKILNYSQNDLIGQSLFDYLHPKDIAKVKEQLSSSDTAPRERLIDAKTGLPV 185
Query: 177 SDSLTP--EYLKSKNQLEFCCHML--RGTI---DPKEPSTYEYVKFIGNFKSLNSVSS-S 228
+TP L S + F C M R ++ D PST K +F +++S
Sbjct: 186 KTDITPGPSRLCSGARRSFFCRMKCNRPSVKVEDKDFPSTCSKKKDRKSFCTIHSTGYLK 245
Query: 229 AHNGFEGTIQRTHRPSYE--DRVCFVATVRL---ATPQFIKEMCTVEEPNEEFTSRHSLE 283
+ + + + P E + C VA RL PQ + V+ + E+ SRH+++
Sbjct: 246 SWPPTKMGLDEDNEPDNEGCNLSCLVAIGRLHSHVVPQPVNGEIRVK--SMEYVSRHAID 303
Query: 284 WKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHVDDLENLAKCHEHLMQ-YGKGKSCYYRFL 342
KF+F+D RA I+ YLP E+LGTS Y+Y+H DD+ +LA+CH ++Q K + Y+F
Sbjct: 304 GKFVFVDQRATAILAYLPQELLGTSCYEYFHQDDIGHLAECHRQVLQTREKITTNCYKFK 363
Query: 343 TKGQQWIWLQTHYYITYHQWNSRPEFIVCTHTVV 376
K +I L++ ++ + W E+IV T+TVV
Sbjct: 364 IKDGSFITLRSRWFSFMNPWTKEVEYIVSTNTVV 397
>gi|71852580 aryl hydrocarbon receptor nuclear translocator-like
isoform a [Homo sapiens]
Length = 625
Score = 161 bits (407), Expect = 3e-39
Identities = 125/394 (31%), Positives = 204/394 (51%), Gaps = 38/394 (9%)
Query: 15 DRDDSSIFDGLVEEDDKDKAKRVSRNKSEKKRRDQFNVLIKELGSMLP---GNARKMDKS 71
D+DD E + K R + ++ EK+RRD+ N I EL S++P +RK+DK
Sbjct: 53 DKDDPHGRLEYTEHQGRIKNAREAHSQIEKRRRDKMNSFIDELASLVPTCNAMSRKLDKL 112
Query: 72 TVLQKSIDFLRKHKEITAQSDASEIRQDWKPTFLSNEEFTQLMLEALDGFFLAIMTD-GS 130
TVL+ ++ ++ + T + ++KPTFLS++E L+L A DGF + D G
Sbjct: 113 TVLRMAVQHMKTLRGATNPYTEA----NYKPTFLSDDELKHLILRAADGFLFVVGCDRGK 168
Query: 131 IIYVSESVTSLLEHLPSDLVDQSIFNFIPEGEHSEVYKILS--------------THLLE 176
I++VSESV +L + +DL+ QS+F+++ + ++V + LS T L
Sbjct: 169 ILFVSESVFKILNYSQNDLIGQSLFDYLHPKDIAKVKEQLSSSDTAPRERLIDAKTGLPV 228
Query: 177 SDSLTP--EYLKSKNQLEFCCHML--RGTI---DPKEPSTYEYVKFIGNFKSLNSVSS-S 228
+TP L S + F C M R ++ D PST K +F +++S
Sbjct: 229 KTDITPGPSRLCSGARRSFFCRMKCNRPSVKVEDKDFPSTCSKKKDRKSFCTIHSTGYLK 288
Query: 229 AHNGFEGTIQRTHRPSYE--DRVCFVATVRL---ATPQFIKEMCTVEEPNEEFTSRHSLE 283
+ + + + P E + C VA RL PQ + V+ + E+ SRH+++
Sbjct: 289 SWPPTKMGLDEDNEPDNEGCNLSCLVAIGRLHSHVVPQPVNGEIRVK--SMEYVSRHAID 346
Query: 284 WKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHVDDLENLAKCHEHLMQ-YGKGKSCYYRFL 342
KF+F+D RA I+ YLP E+LGTS Y+Y+H DD+ +LA+CH ++Q K + Y+F
Sbjct: 347 GKFVFVDQRATAILAYLPQELLGTSCYEYFHQDDIGHLAECHRQVLQTREKITTNCYKFK 406
Query: 343 TKGQQWIWLQTHYYITYHQWNSRPEFIVCTHTVV 376
K +I L++ ++ + W E+IV T+TVV
Sbjct: 407 IKDGSFITLRSRWFSFMNPWTKEVEYIVSTNTVV 440
>gi|42716311 aryl hydrocarbon receptor nuclear translocator-like
isoform a [Homo sapiens]
Length = 625
Score = 161 bits (407), Expect = 3e-39
Identities = 125/394 (31%), Positives = 204/394 (51%), Gaps = 38/394 (9%)
Query: 15 DRDDSSIFDGLVEEDDKDKAKRVSRNKSEKKRRDQFNVLIKELGSMLP---GNARKMDKS 71
D+DD E + K R + ++ EK+RRD+ N I EL S++P +RK+DK
Sbjct: 53 DKDDPHGRLEYTEHQGRIKNAREAHSQIEKRRRDKMNSFIDELASLVPTCNAMSRKLDKL 112
Query: 72 TVLQKSIDFLRKHKEITAQSDASEIRQDWKPTFLSNEEFTQLMLEALDGFFLAIMTD-GS 130
TVL+ ++ ++ + T + ++KPTFLS++E L+L A DGF + D G
Sbjct: 113 TVLRMAVQHMKTLRGATNPYTEA----NYKPTFLSDDELKHLILRAADGFLFVVGCDRGK 168
Query: 131 IIYVSESVTSLLEHLPSDLVDQSIFNFIPEGEHSEVYKILS--------------THLLE 176
I++VSESV +L + +DL+ QS+F+++ + ++V + LS T L
Sbjct: 169 ILFVSESVFKILNYSQNDLIGQSLFDYLHPKDIAKVKEQLSSSDTAPRERLIDAKTGLPV 228
Query: 177 SDSLTP--EYLKSKNQLEFCCHML--RGTI---DPKEPSTYEYVKFIGNFKSLNSVSS-S 228
+TP L S + F C M R ++ D PST K +F +++S
Sbjct: 229 KTDITPGPSRLCSGARRSFFCRMKCNRPSVKVEDKDFPSTCSKKKDRKSFCTIHSTGYLK 288
Query: 229 AHNGFEGTIQRTHRPSYE--DRVCFVATVRL---ATPQFIKEMCTVEEPNEEFTSRHSLE 283
+ + + + P E + C VA RL PQ + V+ + E+ SRH+++
Sbjct: 289 SWPPTKMGLDEDNEPDNEGCNLSCLVAIGRLHSHVVPQPVNGEIRVK--SMEYVSRHAID 346
Query: 284 WKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHVDDLENLAKCHEHLMQ-YGKGKSCYYRFL 342
KF+F+D RA I+ YLP E+LGTS Y+Y+H DD+ +LA+CH ++Q K + Y+F
Sbjct: 347 GKFVFVDQRATAILAYLPQELLGTSCYEYFHQDDIGHLAECHRQVLQTREKITTNCYKFK 406
Query: 343 TKGQQWIWLQTHYYITYHQWNSRPEFIVCTHTVV 376
K +I L++ ++ + W E+IV T+TVV
Sbjct: 407 IKDGSFITLRSRWFSFMNPWTKEVEYIVSTNTVV 440
>gi|31745180 aryl hydrocarbon receptor nuclear translocator-like 2
[Homo sapiens]
Length = 636
Score = 144 bits (363), Expect = 3e-34
Identities = 113/391 (28%), Positives = 192/391 (49%), Gaps = 45/391 (11%)
Query: 19 SSIFDGLVEEDDKDKAKRVSRNKSEKKRRDQFNVLIKELGSMLP---GNARKMDKSTVLQ 75
S + DG E K KA R + +++EK+RRD+ N LI+EL +M+P ARK+DK TVL+
Sbjct: 94 SRVEDG--EHQVKMKAFREAHSQTEKRRRDKMNNLIEELSAMIPQCNPMARKLDKLTVLR 151
Query: 76 KSIDFLRKHKEITAQSDASEIRQDWKPTFLSNEEFTQLMLEALDGFFLAIMTD-GSIIYV 134
++ LR K +T S + +++P+FL + E L+L+ +GF + + G I++V
Sbjct: 152 MAVQHLRSLKGLT----NSYVGSNYRPSFLQDNELRHLILKTAEGFLFVVGCERGKILFV 207
Query: 135 SESVTSLLEHLPSDLVDQSIFNFIPEGEHSEVYKILSTHLLESDSLTPEYLKSKNQLEFC 194
S+SV+ +L + + L QS+F+F+ + ++V + LS+ + S + + +K L+
Sbjct: 208 SKSVSKILNYDQASLTGQSLFDFLHPKDVAKVKEQLSSFDI---SPREKLIDAKTGLQVH 264
Query: 195 CHMLRGTIDPKEPSTYEYVKFIGNFKSLNSVSSSAHNGFEGTIQRTHRPSY--------- 245
++ G S F KS H + ++ HR Y
Sbjct: 265 SNLHAGRTRVYSGSRR---SFFCRIKSCKISVKEEHGCLPNSKKKEHRKFYTIHCTGYLR 321
Query: 246 ----------EDR---------VCFVATVRLATPQFIKEMCTVEEPNEEFTSRHSLEWKF 286
E+R C VA RL + + EF +R ++ KF
Sbjct: 322 SWPPNIVGMEEERNSKKDNSNFTCLVAIGRLQPYIVPQNSGEINVKPTEFITRFAVNGKF 381
Query: 287 LFLDHRAPPIIGYLPFEVLGTSGYDYYHVDDLENLAKCHEHLMQ-YGKGKSCYYRFLTKG 345
+++D RA I+GYLP E+LGTS Y+Y+H DD NL H+ ++Q K + Y+F K
Sbjct: 382 VYVDQRATAILGYLPQELLGTSCYEYFHQDDHNNLTDKHKAVLQSKEKILTDSYKFRAKD 441
Query: 346 QQWIWLQTHYYITYHQWNSRPEFIVCTHTVV 376
++ L++ ++ + W E+IV +T+V
Sbjct: 442 GSFVTLKSQWFSFTNPWTKELEYIVSVNTLV 472
>gi|40254439 endothelial PAS domain protein 1 [Homo sapiens]
Length = 870
Score = 138 bits (348), Expect = 2e-32
Identities = 99/365 (27%), Positives = 173/365 (47%), Gaps = 34/365 (9%)
Query: 30 DKDKAKRVSRNKSEKKR------RDQFNVLIKELGSMLP---GNARKMDKSTVLQKSIDF 80
DK+K + S + EK R R + + EL LP + +DK+++++ +I F
Sbjct: 4 DKEKKRSSSERRKEKSRDAARCRRSKETEVFYELAHELPLPHSVSSHLDKASIMRLAISF 63
Query: 81 LRKHKEITAQSDASEIRQDWKPTFLSNEEFTQLMLEALDGFFLAIMTDGSIIYVSESVTS 140
LR HK +++ +E + ++++ L L+AL+GF + DG +I++SE+++
Sbjct: 64 LRTHKLLSSVCSENESEAE------ADQQMDNLYLKALEGFIAVVTQDGDMIFLSENISK 117
Query: 141 LLEHLPSDLVDQSIFNFIPEGEHSEVYKILSTHLLESDSLTPEYLKSKNQLEF-----CC 195
+ +L SIF+F +H E+ + LS L + + +F C
Sbjct: 118 FMGLTQVELTGHSIFDFTHPCDHEEIRENLS--LKNGSGFGKKSKDMSTERDFFMRMKCT 175
Query: 196 HMLRGTIDPKEPSTYEYVKFIGNFKSLNSVSSSAHNGFEGTIQRTHRPSYEDRVCFVATV 255
RG + +T++ + G K N+ HN G Y++ + +
Sbjct: 176 VTNRGRTVNLKSATWKVLHCTGQVKVYNNCPP--HNSLCG---------YKEPLLSCLII 224
Query: 256 RLATPQFIKEMCTVEEPNEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHV 315
Q M + ++ F SRHS++ KF + D R +IGY P E+LG S Y++YH
Sbjct: 225 MCEPIQHPSHM-DIPLDSKTFLSRHSMDMKFTYCDDRITELIGYHPEELLGRSAYEFYHA 283
Query: 316 DDLENLAKCHEHLMQYGKGKSCYYRFLTKGQQWIWLQTHYYITYHQWNSRPEFIVCTHTV 375
D EN+ K H++L G+ S YR L K ++WL+T + Y+ N +P+ I+C + V
Sbjct: 284 LDSENMTKSHQNLCTKGQVVSGQYRMLAKHGGYVWLETQGTVIYNPRNLQPQCIMCVNYV 343
Query: 376 VSYAE 380
+S E
Sbjct: 344 LSEIE 348
>gi|30795242 aryl hydrocarbon receptor nuclear translocator isoform
3 [Homo sapiens]
Length = 774
Score = 130 bits (326), Expect = 7e-30
Identities = 114/451 (25%), Positives = 208/451 (46%), Gaps = 61/451 (13%)
Query: 29 DDKDKAKRVSRNKSEKKRRDQFNVLIKELGSMLP---GNARKMDKSTVLQKSIDFLRKHK 85
+DK++ R + ++ E++RR++ I EL M+P ARK DK T+L+ ++ ++ +
Sbjct: 69 NDKERFARENHSEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVSHMKSLR 128
Query: 86 EI-TAQSDASEIRQDWKPTFLSNEEFTQLMLEALDGF-FLAIMTDGSIIYVSESVTSLLE 143
+D S +KP+FL+++E L+LEA DGF F+ G ++YVS+SVT +L
Sbjct: 129 GTGNTSTDGS-----YKPSFLTDQELKHLILEAADGFLFIVSCETGRVVYVSDSVTPVLN 183
Query: 144 HLPSDLVDQSIFNFIPEGEHSEVYKILSTHLLESDSLTPEYLKSK--------------- 188
S+ ++++ + + ++ + LST ++LT L K
Sbjct: 184 QPQSEWFGSTLYDQVHPDDVDKLREQLST---SENALTGRILDLKTGTVKKEGQQSSMRM 240
Query: 189 ---NQLEFCCHMLRGT--IDPKEPSTYEYVKF-----IGNFKSLNSVSSSAH-NGF---- 233
++ F C M G+ +DP + +V+ +G+ K H G+
Sbjct: 241 CMGSRRSFICRMRCGSSSVDPVSVNRLSFVRNRCRNGLGSVKDGEPHFVVVHCTGYIKAW 300
Query: 234 --EGTIQRTHRPS--YEDRVCFVATVRLATPQF--IKEMCTVEEPNEEFTSRHSLEWKFL 287
G P + C VA RL +M V +P E F SRH++E F
Sbjct: 301 PPAGVSLPDDDPEAGQGSKFCLVAIGRLQVTSSPNCTDMSNVCQPTE-FISRHNIEGIFT 359
Query: 288 FLDHRAPPIIGYLPFEVLGTSGYDYYHVDDLENLAKCHEHLMQY-GKGKSCYYRFLTKGQ 346
F+DHR +GY P E+LG + ++ H +D + L + +++ G+ S +RF +K Q
Sbjct: 360 FVDHRCVATVGYQPQELLGKNIVEFCHPEDQQLLRDSFQQVVKLKGQVLSVMFRFRSKNQ 419
Query: 347 QWIWLQTHYYITYHQWNSRPEFIVCTHTVVSYAEVRAE-------RRRELGIEESLPETA 399
+W+W++T + + ++ E+I+CT+T V + +R +LG +LP
Sbjct: 420 EWLWMRTSSFTFQNPYSDEIEYIICTNTNVKNSSQEPRPTLSNTIQRPQLGPTANLPLEM 479
Query: 400 AD---KSQDSGSDNRINTVSLKEALERFDHS 427
+ ++ V ++ L ++HS
Sbjct: 480 GSGQLAPRQQQQQTELDMVPGRDGLASYNHS 510
>gi|4502231 aryl hydrocarbon receptor nuclear translocator isoform 1
[Homo sapiens]
Length = 789
Score = 130 bits (326), Expect = 7e-30
Identities = 114/450 (25%), Positives = 207/450 (46%), Gaps = 61/450 (13%)
Query: 30 DKDKAKRVSRNKSEKKRRDQFNVLIKELGSMLP---GNARKMDKSTVLQKSIDFLRKHKE 86
DK++ R + ++ E++RR++ I EL M+P ARK DK T+L+ ++ ++ +
Sbjct: 85 DKERLARENHSEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVSHMKSLRG 144
Query: 87 I-TAQSDASEIRQDWKPTFLSNEEFTQLMLEALDGF-FLAIMTDGSIIYVSESVTSLLEH 144
+D S +KP+FL+++E L+LEA DGF F+ G ++YVS+SVT +L
Sbjct: 145 TGNTSTDGS-----YKPSFLTDQELKHLILEAADGFLFIVSCETGRVVYVSDSVTPVLNQ 199
Query: 145 LPSDLVDQSIFNFIPEGEHSEVYKILSTHLLESDSLTPEYLKSK---------------- 188
S+ ++++ + + ++ + LST ++LT L K
Sbjct: 200 PQSEWFGSTLYDQVHPDDVDKLREQLST---SENALTGRILDLKTGTVKKEGQQSSMRMC 256
Query: 189 --NQLEFCCHMLRGT--IDPKEPSTYEYVKF-----IGNFKSLNSVSSSAH-NGF----- 233
++ F C M G+ +DP + +V+ +G+ K H G+
Sbjct: 257 MGSRRSFICRMRCGSSSVDPVSVNRLSFVRNRCRNGLGSVKDGEPHFVVVHCTGYIKAWP 316
Query: 234 -EGTIQRTHRPS--YEDRVCFVATVRLATPQF--IKEMCTVEEPNEEFTSRHSLEWKFLF 288
G P + C VA RL +M V +P E F SRH++E F F
Sbjct: 317 PAGVSLPDDDPEAGQGSKFCLVAIGRLQVTSSPNCTDMSNVCQPTE-FISRHNIEGIFTF 375
Query: 289 LDHRAPPIIGYLPFEVLGTSGYDYYHVDDLENLAKCHEHLMQY-GKGKSCYYRFLTKGQQ 347
+DHR +GY P E+LG + ++ H +D + L + +++ G+ S +RF +K Q+
Sbjct: 376 VDHRCVATVGYQPQELLGKNIVEFCHPEDQQLLRDSFQQVVKLKGQVLSVMFRFRSKNQE 435
Query: 348 WIWLQTHYYITYHQWNSRPEFIVCTHTVVSYAEVRAE-------RRRELGIEESLPETAA 400
W+W++T + + ++ E+I+CT+T V + +R +LG +LP
Sbjct: 436 WLWMRTSSFTFQNPYSDEIEYIICTNTNVKNSSQEPRPTLSNTIQRPQLGPTANLPLEMG 495
Query: 401 D---KSQDSGSDNRINTVSLKEALERFDHS 427
+ ++ V ++ L ++HS
Sbjct: 496 SGQLAPRQQQQQTELDMVPGRDGLASYNHS 525
>gi|31077211 hypoxia-inducible factor 1, alpha subunit isoform 2
[Homo sapiens]
Length = 735
Score = 129 bits (324), Expect = 1e-29
Identities = 101/362 (27%), Positives = 170/362 (46%), Gaps = 43/362 (11%)
Query: 32 DKAKRVSRNKSEKKR------RDQFNVLIKELGSMLP---GNARKMDKSTVLQKSIDFLR 82
DK K S + EK R R + + + EL LP + +DK++V++ +I +LR
Sbjct: 9 DKKKISSERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASVMRLTISYLR 68
Query: 83 KHKEITAQSDASEIRQDWKPTFLSNEEFTQLMLEALDGFFLAIMTDGSIIYVSESVTSLL 142
K + A +I D K + L+ALDGF + + DG +IY+S++V +
Sbjct: 69 VRKLLDAGD--LDIEDDMKA------QMNCFYLKALDGFVMVLTDDGDMIYISDNVNKYM 120
Query: 143 EHLPSDLVDQSIFNFIPEGEHSEVYKILSTHLLESDSLTPEYLKSKNQLEF-----CCHM 197
+L S+F+F +H E+ ++L TH + L + + Q F C
Sbjct: 121 GLTQFELTGHSVFDFTHPCDHEEMREML-TH---RNGLVKKGKEQNTQRSFFLRMKCTLT 176
Query: 198 LRGTIDPKEPSTYEYVKFIGNFKSLNSVSSSAHNGFEGTIQRTHRPSYEDRVCFVATVRL 257
RG + +T++ + G+ ++ S+ G++ + V +
Sbjct: 177 SRGRTMNIKSATWKVLHCTGHIHVYDTNSNQPQCGYK-------------KPPMTCLVLI 223
Query: 258 ATPQFIKEMCTVEEP--NEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHV 315
P I +E P ++ F SRHSL+ KF + D R ++GY P E+LG S Y+YYH
Sbjct: 224 CEP--IPHPSNIEIPLDSKTFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYEYYHA 281
Query: 316 DDLENLAKCHEHLMQYGKGKSCYYRFLTKGQQWIWLQTHYYITYHQWNSRPEFIVCTHTV 375
D ++L K H + G+ + YR L K ++W++T + Y+ NS+P+ IVC + V
Sbjct: 282 LDSDHLTKTHHDMFTKGQVTTGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYV 341
Query: 376 VS 377
VS
Sbjct: 342 VS 343
>gi|4504385 hypoxia-inducible factor 1, alpha subunit isoform 1
[Homo sapiens]
Length = 826
Score = 129 bits (324), Expect = 1e-29
Identities = 101/362 (27%), Positives = 170/362 (46%), Gaps = 43/362 (11%)
Query: 32 DKAKRVSRNKSEKKR------RDQFNVLIKELGSMLP---GNARKMDKSTVLQKSIDFLR 82
DK K S + EK R R + + + EL LP + +DK++V++ +I +LR
Sbjct: 9 DKKKISSERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASVMRLTISYLR 68
Query: 83 KHKEITAQSDASEIRQDWKPTFLSNEEFTQLMLEALDGFFLAIMTDGSIIYVSESVTSLL 142
K + A +I D K + L+ALDGF + + DG +IY+S++V +
Sbjct: 69 VRKLLDAGD--LDIEDDMKA------QMNCFYLKALDGFVMVLTDDGDMIYISDNVNKYM 120
Query: 143 EHLPSDLVDQSIFNFIPEGEHSEVYKILSTHLLESDSLTPEYLKSKNQLEF-----CCHM 197
+L S+F+F +H E+ ++L TH + L + + Q F C
Sbjct: 121 GLTQFELTGHSVFDFTHPCDHEEMREML-TH---RNGLVKKGKEQNTQRSFFLRMKCTLT 176
Query: 198 LRGTIDPKEPSTYEYVKFIGNFKSLNSVSSSAHNGFEGTIQRTHRPSYEDRVCFVATVRL 257
RG + +T++ + G+ ++ S+ G++ + V +
Sbjct: 177 SRGRTMNIKSATWKVLHCTGHIHVYDTNSNQPQCGYK-------------KPPMTCLVLI 223
Query: 258 ATPQFIKEMCTVEEP--NEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHV 315
P I +E P ++ F SRHSL+ KF + D R ++GY P E+LG S Y+YYH
Sbjct: 224 CEP--IPHPSNIEIPLDSKTFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYEYYHA 281
Query: 316 DDLENLAKCHEHLMQYGKGKSCYYRFLTKGQQWIWLQTHYYITYHQWNSRPEFIVCTHTV 375
D ++L K H + G+ + YR L K ++W++T + Y+ NS+P+ IVC + V
Sbjct: 282 LDSDHLTKTHHDMFTKGQVTTGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYV 341
Query: 376 VS 377
VS
Sbjct: 342 VS 343
>gi|90421311 hypoxia inducible factor 3, alpha subunit isoform c
[Homo sapiens]
Length = 669
Score = 117 bits (293), Expect = 4e-26
Identities = 96/391 (24%), Positives = 172/391 (43%), Gaps = 54/391 (13%)
Query: 24 GLVEEDDKDKAKRVSRNKSEKKRRDQFNVLIKELGSMLP---GNARKMDKSTVLQKSIDF 80
GL + ++ + + RR Q ++ +L LP G + +DK+++++ +I +
Sbjct: 4 GLQRARSTTELRKEKSRDAARSRRSQETEVLYQLAHTLPFARGVSAHLDKASIMRLTISY 63
Query: 81 LRKHKEITAQSDASEIRQDWKPTFLSNEEFTQLMLEALDGFFLAIMTDGSIIYVSESVTS 140
LR H+ A +W E L+AL+GF + + +G + Y+SE+V+
Sbjct: 64 LRMHRLCAAG--------EWNQVGAGGEPLDACYLKALEGFVMVLTAEGDMAYLSENVSK 115
Query: 141 LLEHLPSDLVDQSIFNFIPEGEHSEVYKILSTHLLESDSLTPEYLKSKNQLE------FC 194
L +L+ SIF+FI + E+ D+LTP+ S+ ++E F
Sbjct: 116 HLGLSQLELIGHSIFDFIHPCDQEEL----------QDALTPQQTLSRRKVEAPTERCFS 165
Query: 195 CHML-----RGTIDPKEPSTYEYVKFIGNFKSLNSVSSSAHNGFEGTIQRTHRPSYEDRV 249
M RG + +T++ + G+ ++ + ++ G P E +
Sbjct: 166 LRMKSTLTSRGRTLNLKAATWKVLNCSGHMRAYKPPAQTSPAG---------SPDSEPPL 216
Query: 250 CFVATVRLATPQFIKEMCTVEEP--NEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGT 307
+ + A P ++E P F SRHSL+ KF + D R + GY P +++G
Sbjct: 217 QCLVLICEAIPH----PGSLEPPLGRGAFLSRHSLDMKFTYCDDRIAEVAGYSPDDLIGC 272
Query: 308 SGYDYYHVDDLENLAKCHEHLMQYGKGKSCYYRFLTKGQQWIWLQTHYYITYHQWNSRPE 367
S Y+Y H D + ++K L+ G+ + YRFL + ++W QT + + E
Sbjct: 273 SAYEYIHALDSDAVSKSIHTLLSKGQAVTGQYRFLARSGGYLWTQTQATVVSGGRGPQSE 332
Query: 368 FIVCTHTVVSYAEVRAERRRELGIEESLPET 398
IVC H ++S E E G+ SL +T
Sbjct: 333 SIVCVHFLISQVE-------ETGVVLSLEQT 356
>gi|23065535 hypoxia inducible factor 3, alpha subunit isoform a
[Homo sapiens]
Length = 667
Score = 117 bits (292), Expect = 6e-26
Identities = 97/384 (25%), Positives = 173/384 (45%), Gaps = 59/384 (15%)
Query: 31 KDKAKRVSRNKSEKKRRDQFNVLIKELGSMLP---GNARKMDKSTVLQKSIDFLRKHKEI 87
K+K++ +R+ RR Q ++ +L LP G + +DK+++++ +I +LR H+
Sbjct: 14 KEKSRDAARS-----RRSQETEVLYQLAHTLPFARGVSAHLDKASIMRLTISYLRMHRLC 68
Query: 88 TAQSDASEIRQDWKPTFLSNEEFTQLMLEALDGFFLAIMTDGSIIYVSESVTSLLEHLPS 147
A +W E L+AL+GF + + +G + Y+SE+V+ L
Sbjct: 69 AAG--------EWNQVGAGGEPLDACYLKALEGFVMVLTAEGDMAYLSENVSKHLGLSQL 120
Query: 148 DLVDQSIFNFIPEGEHSEVYKILSTHLLESDSLTPEYLKSKNQLE------FCCHML--- 198
+L+ SIF+FI + E+ D+LTP+ S+ ++E F M
Sbjct: 121 ELIGHSIFDFIHPCDQEEL----------QDALTPQQTLSRRKVEAPTERCFSLRMKSTL 170
Query: 199 --RGTIDPKEPSTYEYVKFIGNFKSLNSVSSSAHNGFEGTIQRTHRPSYEDRVCFVATVR 256
RG + +T++ + G+ ++ + ++ G P E + + +
Sbjct: 171 TSRGRTLNLKAATWKVLNCSGHMRAYKPPAQTSPAG---------SPDSEPPLQCLVLIC 221
Query: 257 LATPQFIKEMCTVEEP--NEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYH 314
A P ++E P F SRHSL+ KF + D R + GY P +++G S Y+Y H
Sbjct: 222 EAIPH----PGSLEPPLGRGAFLSRHSLDMKFTYCDDRIAEVAGYSPDDLIGCSAYEYIH 277
Query: 315 VDDLENLAKCHEHLMQYGKGKSCYYRFLTKGQQWIWLQTHYYITYHQWNSRPEFIVCTHT 374
D + ++K L+ G+ + YRFL + ++W QT + + E IVC H
Sbjct: 278 ALDSDAVSKSIHTLLSKGQAVTGQYRFLARSGGYLWTQTQATVVSGGRGPQSESIVCVHF 337
Query: 375 VVSYAEVRAERRRELGIEESLPET 398
++S E E G+ SL +T
Sbjct: 338 LISQVE-------ETGVVLSLEQT 354
>gi|21614542 single-minded homolog 1 [Homo sapiens]
Length = 766
Score = 113 bits (283), Expect = 6e-25
Identities = 111/447 (24%), Positives = 195/447 (43%), Gaps = 46/447 (10%)
Query: 31 KDKAKRVSRNKSEKKRRDQFNVLIKELGSMLP---GNARKMDKSTVLQKSIDFLRKHKEI 87
K+K+K +R + EK+ + + EL +LP ++DK+++++ + +L K + +
Sbjct: 2 KEKSKNAARTRREKENSEFY-----ELAKLLPLPSAITSQLDKASIIRLTTSYL-KMRVV 55
Query: 88 TAQSDASEIRQDWKPTFLSN--EEFTQLMLEALDGFFLAIMTDGSIIYVSESVTSLLEHL 145
+ + + L N E +L+ LDGF + DG I+Y+SE+ + L
Sbjct: 56 FPEGLGEAWGHSSRTSPLDNVGRELGSHLLQTLDGFIFVVAPDGKIMYISETASVHLGLS 115
Query: 146 PSDLVDQSIFNFIPEGEHSEVYKILSTHLLESDSLTPEY-LKSKNQLEFCCHMLRGTIDP 204
+L SI+ +I +H E+ +L+ H EY ++ L C + +
Sbjct: 116 QVELTGNSIYEYIHPADHDEMTAVLTAHQPYHSHFVQEYEIERSFFLRMKCVLAKRNAG- 174
Query: 205 KEPSTYEYVKFIGNFKSLNSVSSSAHNGFEGTIQRTHRPSYEDRVCFVATVRLATPQFIK 264
Y+ + G K S + F+G Q V VA P +
Sbjct: 175 LTCGGYKVIHCSGYLKIRQY--SLDMSPFDGCYQN---------VGLVAVGHSLPPSAVT 223
Query: 265 EMCTVEEPNEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHVDDLENLAKC 324
E ++ + F R SL+ K +FLD R + GY P +++ + Y + H D +L
Sbjct: 224 E---IKLHSNMFMFRASLDMKLIFLDSRVAELTGYEPQDLIEKTLYHHVHGCDTFHLRCA 280
Query: 325 HEHLMQYGKGKSCYYRFLTKGQQWIWLQTHYYITYHQWNSRPEFIVCTHTVVSYAEVRAE 384
H L+ G+ + YYRFL K W+W+Q++ I ++ +SRP IV + V++ E +
Sbjct: 281 HHLLLVKGQVTTKYYRFLAKHGGWVWVQSYATIVHNSRSSRPHCIVSVNYVLTDTEYK-- 338
Query: 385 RRRELGIEESLPETAADK--------SQDSGSDNRINTVS-LKEALERFDHSPTPSASSR 435
G++ SL + +A K S + +DNR S L + + SP P S
Sbjct: 339 -----GLQLSLDQISASKPAFSYTSSSTPTMTDNRKGAKSRLSSSKSKSRTSPYPQYSGF 393
Query: 436 SSRKSSHTAVSDPSSTPTKIPTDTSTP 462
+ +S S +P TDT++P
Sbjct: 394 HTERSESDHDSQWGGSPL---TDTASP 417
>gi|68303555 aryl hydrocarbon receptor nuclear translocator 2 [Homo
sapiens]
Length = 717
Score = 110 bits (275), Expect = 5e-24
Identities = 131/552 (23%), Positives = 228/552 (41%), Gaps = 71/552 (12%)
Query: 29 DDKD-----KAKRVSRNKSEKKRRDQFNVLIKELGSMLP---GNARKMDKSTVLQKSIDF 80
DD+D K R + ++ E++RR++ I EL M+P ARK DK T+L+ ++
Sbjct: 53 DDEDGEGPSKFSRENHSEIERRRRNKMTQYITELSDMVPTCSALARKPDKLTILRMAVSH 112
Query: 81 LRKHKEITAQSDASEIRQDWKPTFLSNEEFTQLMLEALDGFFLAIMTD-GSIIYVSESVT 139
++ + +S +KP+FL+ +E L+LEA DGF + + G +IYVS+SVT
Sbjct: 113 MKSMRGTGNKSTDGA----YKPSFLTEQELKHLILEAADGFLFVVAAETGRVIYVSDSVT 168
Query: 140 SLLEHLPSDLVDQSIFNFIPEGEHSEVYKILSTHLLESDSLTPEYLKSK----------- 188
+L S+ +++ + + ++ + L T +S+T L K
Sbjct: 169 PVLNQPQSEWFGSTLYEQVHPDDVEKLREQLCT---SENSMTGRILDLKTGTVKKEGQQS 225
Query: 189 -------NQLEFCCHMLRGTID----PKEPSTYEYVKF---IGNFKSLNSVSSSAH-NGF 233
++ F C M G P T +F +G K + + H G+
Sbjct: 226 SMRMCMGSRRSFICRMRCGNAPLDHLPLNRITTMRKRFRNGLGPVKEGEAQYAVVHCTGY 285
Query: 234 EGTIQRTHRPSYED--------RVCFVATVRL--ATPQFIKEMCTVEEPNEEFTSRHSLE 283
E+ + C VA RL + +M + P E F SRH+ +
Sbjct: 286 IKAWPPAGMTIPEEDADVGQGSKYCLVAIGRLQVTSSPVCMDMNGMSVPTE-FLSRHNSD 344
Query: 284 WKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHVDDLENLAKCHEHLMQY-GKGKSCYYRFL 342
F+D R +IGY P ++LG ++ H +D +L + + +++ G+ S YRF
Sbjct: 345 GIITFVDPRCISVIGYQPQDLLGKDILEFCHPEDQSHLRESFQQVVKLKGQVLSVMYRFR 404
Query: 343 TKGQQWIWLQTHYYITYHQWNSRPEFIVCTHTVV-----SYAEVRAERRRELG----IEE 393
TK ++W+ ++T + + ++ E+I+CT+T V AE+ +R L +
Sbjct: 405 TKNREWMLIRTSSFTFQNPYSDEIEYIICTNTNVKQLQQQQAELEVHQRDGLSSYDLSQV 464
Query: 394 SLPETAADKSQDSGSDNRINTVSLKEALERFDHSPTPSASSRSSRKSSHTAVSDPS--ST 451
+P A + S + + + +E RF ++S SS +A S
Sbjct: 465 PVPNLPAGVHEAGKSVEKADAIFSQERDPRFAEMFAGISASEKKMMSSASAAGTQQIYSQ 524
Query: 452 PTKIPTDTSTPPRQHLPAHEKMVQRRSSFSSQSINSQSVGSSLTQPVMSQATNLP----- 506
+ P+ S H V S SS N + L Q ++ + P
Sbjct: 525 GSPFPSGHSGKAFSSSVVHVPGVNDIQSSSSTGQNMSQISRQLNQSQVAWTGSRPPFPGQ 584
Query: 507 -IPQGMSQFQFS 517
IP S+ Q S
Sbjct: 585 QIPSQSSKTQSS 596
>gi|4827004 single-minded homolog 2 long isoform [Homo sapiens]
Length = 667
Score = 105 bits (261), Expect = 2e-22
Identities = 93/381 (24%), Positives = 171/381 (44%), Gaps = 32/381 (8%)
Query: 31 KDKAKRVSRNKSEKKRRDQFNVLIKELGSMLP---GNARKMDKSTVLQKSIDFLRKHKEI 87
K+K+K ++ + EK+ + + EL +LP ++DK+++++ + +L+
Sbjct: 2 KEKSKNAAKTRREKENGEFY-----ELAKLLPLPSAITSQLDKASIIRLTTSYLKMRAVF 56
Query: 88 T-AQSDASEIRQDWKPTFLSNEEFTQLMLEALDGFFLAIMTDGSIIYVSESVTSLLEHLP 146
DA P +E +L+ LDGF + +DG I+Y+SE+ + L
Sbjct: 57 PEGLGDAWGQPSRAGPLDGVAKELGSHLLQTLDGFVFVVASDGKIMYISETASVHLGLSQ 116
Query: 147 SDLVDQSIFNFIPEGEHSEVYKILSTHLLESDSLTPEY-LKSKNQLEFCCHMLRGTIDPK 205
+L SI+ +I +H E+ +L+ H L EY ++ L C + +
Sbjct: 117 VELTGNSIYEYIHPSDHDEMTAVLTAHQPLHHHLLQEYEIERSFFLRMKCVLAKRNAG-L 175
Query: 206 EPSTYEYVKFIGNFKSLNSVSSSAHNGFEGTIQRTHRPSYEDRVCFVATVRLATPQFIKE 265
S Y+ + G K + + + S V VA + P I E
Sbjct: 176 TCSGYKVIHCSGYLKIRQYM-----------LDMSLYDSCYQIVGLVAVGQSLPPSAITE 224
Query: 266 MCTVEEPNEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHVDDLENLAKCH 325
++ + F R SL+ K +FLD R + GY P +++ + Y + H D+ +L H
Sbjct: 225 ---IKLYSNMFMFRASLDLKLIFLDSRVTEVTGYEPQDLIEKTLYHHVHGCDVFHLRYAH 281
Query: 326 EHLMQYGKGKSCYYRFLTKGQQWIWLQTHYYITYHQWNSRPEFIVCTHTVVSYAEVRAER 385
L+ G+ + YYR L+K W+W+Q++ + ++ +SRP IV + V++ E +
Sbjct: 282 HLLLVKGQVTTKYYRLLSKRGGWVWVQSYATVVHNSRSSRPHCIVSVNYVLTEIEYKE-- 339
Query: 386 RRELGIEESLPETAADKSQDS 406
++ SL + + KSQDS
Sbjct: 340 -----LQLSLEQVSTAKSQDS 355
>gi|194239684 single-minded homolog 2 short isoform [Homo sapiens]
Length = 570
Score = 105 bits (261), Expect = 2e-22
Identities = 93/381 (24%), Positives = 171/381 (44%), Gaps = 32/381 (8%)
Query: 31 KDKAKRVSRNKSEKKRRDQFNVLIKELGSMLP---GNARKMDKSTVLQKSIDFLRKHKEI 87
K+K+K ++ + EK+ + + EL +LP ++DK+++++ + +L+
Sbjct: 2 KEKSKNAAKTRREKENGEFY-----ELAKLLPLPSAITSQLDKASIIRLTTSYLKMRAVF 56
Query: 88 T-AQSDASEIRQDWKPTFLSNEEFTQLMLEALDGFFLAIMTDGSIIYVSESVTSLLEHLP 146
DA P +E +L+ LDGF + +DG I+Y+SE+ + L
Sbjct: 57 PEGLGDAWGQPSRAGPLDGVAKELGSHLLQTLDGFVFVVASDGKIMYISETASVHLGLSQ 116
Query: 147 SDLVDQSIFNFIPEGEHSEVYKILSTHLLESDSLTPEY-LKSKNQLEFCCHMLRGTIDPK 205
+L SI+ +I +H E+ +L+ H L EY ++ L C + +
Sbjct: 117 VELTGNSIYEYIHPSDHDEMTAVLTAHQPLHHHLLQEYEIERSFFLRMKCVLAKRNAG-L 175
Query: 206 EPSTYEYVKFIGNFKSLNSVSSSAHNGFEGTIQRTHRPSYEDRVCFVATVRLATPQFIKE 265
S Y+ + G K + + + S V VA + P I E
Sbjct: 176 TCSGYKVIHCSGYLKIRQYM-----------LDMSLYDSCYQIVGLVAVGQSLPPSAITE 224
Query: 266 MCTVEEPNEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHVDDLENLAKCH 325
++ + F R SL+ K +FLD R + GY P +++ + Y + H D+ +L H
Sbjct: 225 ---IKLYSNMFMFRASLDLKLIFLDSRVTEVTGYEPQDLIEKTLYHHVHGCDVFHLRYAH 281
Query: 326 EHLMQYGKGKSCYYRFLTKGQQWIWLQTHYYITYHQWNSRPEFIVCTHTVVSYAEVRAER 385
L+ G+ + YYR L+K W+W+Q++ + ++ +SRP IV + V++ E +
Sbjct: 282 HLLLVKGQVTTKYYRLLSKRGGWVWVQSYATVVHNSRSSRPHCIVSVNYVLTEIEYKE-- 339
Query: 386 RRELGIEESLPETAADKSQDS 406
++ SL + + KSQDS
Sbjct: 340 -----LQLSLEQVSTAKSQDS 355
>gi|90421316 hypoxia inducible factor 3, alpha subunit isoform b
[Homo sapiens]
Length = 613
Score = 103 bits (256), Expect = 9e-22
Identities = 85/338 (25%), Positives = 148/338 (43%), Gaps = 51/338 (15%)
Query: 74 LQKSIDFLRKHKEITAQSDASEIRQDWKPTFLSNEEFTQLMLEALDGFFLAIMTDGSIIY 133
++ +I +LR H+ A +W E L+AL+GF + + +G + Y
Sbjct: 1 MRLTISYLRMHRLCAAG--------EWNQVGAGGEPLDACYLKALEGFVMVLTAEGDMAY 52
Query: 134 VSESVTSLLEHLPSDLVDQSIFNFIPEGEHSEVYKILSTHLLESDSLTPEYLKSKNQLE- 192
+SE+V+ L +L+ SIF+FI + E+ D+LTP+ S+ ++E
Sbjct: 53 LSENVSKHLGLSQLELIGHSIFDFIHPCDQEEL----------QDALTPQQTLSRRKVEA 102
Query: 193 -----FCCHML-----RGTIDPKEPSTYEYVKFIGNFKSLNSVSSSAHNGFEGTIQRTHR 242
F M RG + +T++ + G+ ++ + ++ G
Sbjct: 103 PTERCFSLRMKSTLTSRGRTLNLKAATWKVLNCSGHMRAYKPPAQTSPAG---------S 153
Query: 243 PSYEDRVCFVATVRLATPQFIKEMCTVEEP--NEEFTSRHSLEWKFLFLDHRAPPIIGYL 300
P E + + + A P ++E P F SRHSL+ KF + D R + GY
Sbjct: 154 PDSEPPLQCLVLICEAIPH----PGSLEPPLGRGAFLSRHSLDMKFTYCDDRIAEVAGYS 209
Query: 301 PFEVLGTSGYDYYHVDDLENLAKCHEHLMQYGKGKSCYYRFLTKGQQWIWLQTHYYITYH 360
P +++G S Y+Y H D + ++K L+ G+ + YRFL + ++W QT +
Sbjct: 210 PDDLIGCSAYEYIHALDSDAVSKSIHTLLSKGQAVTGQYRFLARSGGYLWTQTQATVVSG 269
Query: 361 QWNSRPEFIVCTHTVVSYAEVRAERRRELGIEESLPET 398
+ E IVC H ++S E E G+ SL +T
Sbjct: 270 GRGPQSESIVCVHFLISQVE-------ETGVVLSLEQT 300
>gi|157785548 PAS domain containing 1 [Homo sapiens]
Length = 773
Score = 102 bits (253), Expect = 2e-21
Identities = 59/188 (31%), Positives = 104/188 (55%), Gaps = 15/188 (7%)
Query: 93 ASEIRQDWKPTFLSNEEFTQLMLEALDGFFLAIMTDGSIIYVSESVTSLLEHLPSDLVDQ 152
+S+ + +W P+F + + F Q+ L+ LDGF + + TDG II V+E+++SLL HLP+++V +
Sbjct: 16 SSQRKLNWIPSFPTYDYFNQVTLQLLDGFMITLSTDGVIICVAENISSLLGHLPAEIVGK 75
Query: 153 SIFNFIPEGEHSEVYK--ILSTHLLESDSLTPEYLKSKNQLEFCCHMLRGTIDPKEPSTY 210
+ + +P+ E EVY+ IL LL S++ +EFCCH+ RG ++ + S Y
Sbjct: 76 KLLSLLPDEEKDEVYQKIILKFPLLNSET----------HIEFCCHLKRGNVEHGDSSAY 125
Query: 211 EYVKFIGNFKSLNSVSSSAHNGFEGT---IQRTHRPSYEDRVCFVATVRLATPQFIKEMC 267
E VKFI N + + + +G + EDR+ V V + Q ++++
Sbjct: 126 ENVKFIVNVRDICNEFPVVFSGLFSSHLCADFAACVPQEDRLYLVGNVCILRTQLLQQLY 185
Query: 268 TVEEPNEE 275
T + ++E
Sbjct: 186 TSKAVSDE 193
Score = 32.3 bits (72), Expect = 1.9
Identities = 16/40 (40%), Positives = 24/40 (60%)
Query: 517 SAQLGAMQHLKDQLEQRTRMIEANIHRQQEELRKIQEQLQ 556
S +L M+ LK+QLE+RT ++ I QQ L + + LQ
Sbjct: 371 SQELELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQ 410
>gi|4502003 aryl hydrocarbon receptor [Homo sapiens]
Length = 848
Score = 98.6 bits (244), Expect = 2e-20
Identities = 87/355 (24%), Positives = 159/355 (44%), Gaps = 25/355 (7%)
Query: 39 RNKSEKKRRDQFNVLIKELGSMLP---GNARKMDKSTVLQKSIDFLRKHK--EITAQSDA 93
++ K+ RD+ N + L S+LP K+DK +VL+ S+ +LR ++ +S
Sbjct: 32 KSNPSKRHRDRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFFDVALKSSP 91
Query: 94 SEIRQDWKPTFLS-------NEEFTQLMLEALDGFFLAIMTDGSIIYVSESVTSLLEHLP 146
+E R + + N + + +L+AL+GF L + TD + Y S ++ L
Sbjct: 92 TE-RNGGQDNCRAANFREGLNLQEGEFLLQALNGFVLVVTTDALVFYASSTIQDYLGFQQ 150
Query: 147 SDLVDQSIFNFIPEGEHSEVYKILSTHLLESDSL-TPEYLKSKNQLEFCCHMLRGTIDPK 205
SD++ QS++ I + +E + L L S + + ++ L P
Sbjct: 151 SDVIHQSVYELIHTEDRAEFQRQLHWALNPSQCTESGQGIEEATGLPQTVVCYNPDQIPP 210
Query: 206 EPSTYEYVKFIGNFKSL--NSVSSSAHNGFEGTIQRTHRPSYEDRVCFV-----ATVRLA 258
E S FI + L NS A N F+G ++ H + + + A +A
Sbjct: 211 ENSPLMERCFICRLRCLLDNSSGFLAMN-FQGKLKYLHGQKKKGKDGSILPPQLALFAIA 269
Query: 259 TPQFIKEMCTVEEPNEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGT-SGYDYYHVDD 317
TP + + N F ++H L++ + D + ++GY E+ SGY + H D
Sbjct: 270 TPLQPPSILEIRTKNFIFRTKHKLDFTPIGCDAKGRIVLGYTEAELCTRGSGYQFIHAAD 329
Query: 318 LENLAKCHEHLMQYGKGKSCYYRFLTKGQQWIWLQTHYYITYHQWNSRPEFIVCT 372
+ A+ H +++ G+ +R LTK +W W+Q++ + Y N RP++I+ T
Sbjct: 330 MLYCAESHIRMIKTGESGMIVFRLLTKNNRWTWVQSNARLLYK--NGRPDYIIVT 382
>gi|5729858 nuclear receptor coactivator 2 [Homo sapiens]
Length = 1464
Score = 89.7 bits (221), Expect = 1e-17
Identities = 85/354 (24%), Positives = 162/354 (45%), Gaps = 32/354 (9%)
Query: 39 RNKSEKKRRDQFNVLIKELGSMLPGNAR-------KMDKSTVLQKSIDFLR--KHKEITA 89
+ +EK+ R+Q N I+EL ++ N K DK +L++++ +R K +E A
Sbjct: 31 KRNTEKRNREQENKYIEELAELIFANFNDIDNFNFKPDKCAILKETVKQIRQIKEQEKAA 90
Query: 90 QSDASEIRQ-DWKPT---FLSNEEFTQLMLEALDGFFLAIMTDGSIIYVSESVTSLLEHL 145
++ E+++ D T + + +MLEALDGFF + +G++++VSE+VT L +
Sbjct: 91 AANIDEVQKSDVSSTGQGVIDKDALGPMMLEALDGFFFVVNLEGNVVFVSENVTQYLRYN 150
Query: 146 PSDLVDQSIFNFIPEGEHSEVYK-ILSTHLLESDSLTPEYLKSKNQLEFCCHMLRGTIDP 204
+L+++S+++ + G+H+E K +L ++ S + E + +N F C ML +
Sbjct: 151 QEELMNKSVYSILHVGDHTEFVKNLLPKSIVNGGSWSGEPPR-RNSHTFNCRMLVKPLPD 209
Query: 205 KEPSTYEYVKFIGNFKSLNSVSSSAHNGFEGTIQRTHRPSYED-RVCFVATVRLATPQFI 263
E ++ + ++++ + S ++ + ED + C + R +
Sbjct: 210 SEEEGHDNQEAHQKYETMQCFAVSQ--------PKSIKEEGEDLQSCLICVARRVP---M 258
Query: 264 KEMCTVEEPNEEFTSRHSLEWKFLFLD---HRAPPIIGYLPFEVLGTSGYDYYHVDDLEN 320
KE V +E FT+R L+ K LD RA G+ + H + +
Sbjct: 259 KER-PVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLVRRCIQKFHAQHEGESVS 317
Query: 321 LAKCHEH-LMQYGKGKSCYYRFLTKGQQWIWLQTHYYITYHQWNSRPEFIVCTH 373
AK H H +++ G S YRF + QT + Q + P+ ++ H
Sbjct: 318 YAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQTTNEPQLVISLH 371
>gi|11545847 neuronal PAS domain protein 3 isoform 1 [Homo sapiens]
Length = 901
Score = 88.2 bits (217), Expect = 3e-17
Identities = 92/433 (21%), Positives = 185/433 (42%), Gaps = 57/433 (13%)
Query: 28 EDDKDKAKRVSRNKSEKKR------RDQFNVLIKELGSMLPGNAR---KMDKSTVLQKSI 78
+ D + +R+ + EK R R + N EL +LP A ++DK+++++ +I
Sbjct: 9 QQDPSRRERLQALRKEKSRDAARSRRGKENFEFYELAKLLPLPAAITSQLDKASIIRLTI 68
Query: 79 DFLRKHKEITAQSDAS-EIRQDW--------------KPTFLSNEEFTQLM----LEALD 119
+L K ++ Q D +R + P+ L+ E F + L++LD
Sbjct: 69 SYL-KMRDFANQGDPPWNLRMEGPPPNTSVKGAQRRRSPSALAIEVFEAHLGSHILQSLD 127
Query: 120 GFFLAIMTDGSIIYVSESVTSLLEHLPSDLVDQSIFNFIPEGEHSEVYKILSTHLLESDS 179
GF A+ +G +Y+SE+V+ L +L S+F+++ G+H E+ + L L
Sbjct: 128 GFVFALNQEGKFLYISETVSIYLGLSQVELTGSSVFDYVHPGDHVEMAEQLGMKLPPGRG 187
Query: 180 LTPEYLKSKNQLEFCCHMLRGTIDPKEPS---------TYEYVKFIGNFKSLNS----VS 226
L + T +P E + T E FI +L +
Sbjct: 188 LLSQGTAEDGASSASSSSQSETPEPVESTSPSLLTTDNTLERSFFIRMKSTLTKRGVHIK 247
Query: 227 SSAHNGFEGT------IQRTHRPSYEDRVCFVATVRLATPQFIKEMCTVEEPNEE---FT 277
SS + T + +H + ++ + V A P T+ E + F
Sbjct: 248 SSGYKVIHITGRLRLRVSLSHGRTVPSQIMGLVVVAHALPP-----PTINEVRIDCHMFV 302
Query: 278 SRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHVDDLENLAKCHEHLMQYGKGKSC 337
+R +++ ++ ++R + P +++G Y + H +D+E + H L+ G+ +
Sbjct: 303 TRVNMDLNIIYCENRISDYMDLTPVDIVGKRCYHFIHAEDVEGIRHSHLDLLNKGQCVTK 362
Query: 338 YYRFLTKGQQWIWLQTHYYITYHQWNSRPEFIVCTHTVVSYAEVRAERRRELGIEESLPE 397
YYR++ K +IW+Q+ I + N+ + I+ + ++S E + + ++ LPE
Sbjct: 363 YYRWMQKNGGYIWIQSSATIAINAKNANEKNIIWVNYLLSNPEYK-DTPMDIAQLPHLPE 421
Query: 398 TAADKSQDSGSDN 410
++ S+ S S++
Sbjct: 422 KTSESSETSDSES 434
>gi|22538457 nuclear receptor coactivator 1 isoform 2 [Homo sapiens]
Length = 1399
Score = 84.3 bits (207), Expect = 4e-16
Identities = 56/185 (30%), Positives = 96/185 (51%), Gaps = 19/185 (10%)
Query: 40 NKSEKKRRDQFNVLIKELGSMLPGNAR-------KMDKSTVLQKSIDFLRKHKEITAQSD 92
+ +EK+RR+Q N ++EL +L N K DK +L+K++D ++ K + +
Sbjct: 29 SSTEKRRREQENKYLEELAELLSANISDIDSLSVKPDKCKILKKTVDQIQLMKRMEQEKS 88
Query: 93 ASEIRQDWKPTFLSN--------EEFTQLMLEALDGFFLAIMTDGSIIYVSESVTSLLEH 144
++ D + + +S+ E L+LEALDGFF + +G I++VSE+VTS L +
Sbjct: 89 TTD--DDVQKSDISSSSQGVIEKESLGPLLLEALDGFFFVVNCEGRIVFVSENVTSYLGY 146
Query: 145 LPSDLVDQSIFNFIPEGEHSEVYKILSTHLLESDSLTPEYLKSKNQLEFCCHMLRGTIDP 204
+L++ S+++ + G+H+E K L L + P+ +N F C ML P
Sbjct: 147 NQEELMNTSVYSILHVGDHAEFVKNLLPKSLVNGVPWPQEATRRNSHTFNCRML--IHPP 204
Query: 205 KEPST 209
EP T
Sbjct: 205 DEPGT 209
>gi|22538459 nuclear receptor coactivator 1 isoform 3 [Homo sapiens]
Length = 1440
Score = 84.3 bits (207), Expect = 4e-16
Identities = 56/185 (30%), Positives = 96/185 (51%), Gaps = 19/185 (10%)
Query: 40 NKSEKKRRDQFNVLIKELGSMLPGNAR-------KMDKSTVLQKSIDFLRKHKEITAQSD 92
+ +EK+RR+Q N ++EL +L N K DK +L+K++D ++ K + +
Sbjct: 29 SSTEKRRREQENKYLEELAELLSANISDIDSLSVKPDKCKILKKTVDQIQLMKRMEQEKS 88
Query: 93 ASEIRQDWKPTFLSN--------EEFTQLMLEALDGFFLAIMTDGSIIYVSESVTSLLEH 144
++ D + + +S+ E L+LEALDGFF + +G I++VSE+VTS L +
Sbjct: 89 TTD--DDVQKSDISSSSQGVIEKESLGPLLLEALDGFFFVVNCEGRIVFVSENVTSYLGY 146
Query: 145 LPSDLVDQSIFNFIPEGEHSEVYKILSTHLLESDSLTPEYLKSKNQLEFCCHMLRGTIDP 204
+L++ S+++ + G+H+E K L L + P+ +N F C ML P
Sbjct: 147 NQEELMNTSVYSILHVGDHAEFVKNLLPKSLVNGVPWPQEATRRNSHTFNCRML--IHPP 204
Query: 205 KEPST 209
EP T
Sbjct: 205 DEPGT 209
>gi|22538455 nuclear receptor coactivator 1 isoform 1 [Homo sapiens]
Length = 1441
Score = 84.3 bits (207), Expect = 4e-16
Identities = 56/185 (30%), Positives = 96/185 (51%), Gaps = 19/185 (10%)
Query: 40 NKSEKKRRDQFNVLIKELGSMLPGNAR-------KMDKSTVLQKSIDFLRKHKEITAQSD 92
+ +EK+RR+Q N ++EL +L N K DK +L+K++D ++ K + +
Sbjct: 29 SSTEKRRREQENKYLEELAELLSANISDIDSLSVKPDKCKILKKTVDQIQLMKRMEQEKS 88
Query: 93 ASEIRQDWKPTFLSN--------EEFTQLMLEALDGFFLAIMTDGSIIYVSESVTSLLEH 144
++ D + + +S+ E L+LEALDGFF + +G I++VSE+VTS L +
Sbjct: 89 TTD--DDVQKSDISSSSQGVIEKESLGPLLLEALDGFFFVVNCEGRIVFVSENVTSYLGY 146
Query: 145 LPSDLVDQSIFNFIPEGEHSEVYKILSTHLLESDSLTPEYLKSKNQLEFCCHMLRGTIDP 204
+L++ S+++ + G+H+E K L L + P+ +N F C ML P
Sbjct: 147 NQEELMNTSVYSILHVGDHAEFVKNLLPKSLVNGVPWPQEATRRNSHTFNCRML--IHPP 204
Query: 205 KEPST 209
EP T
Sbjct: 205 DEPGT 209
>gi|41281831 neuronal PAS domain protein 3 isoform 2 [Homo sapiens]
Length = 920
Score = 83.6 bits (205), Expect = 7e-16
Identities = 94/452 (20%), Positives = 187/452 (41%), Gaps = 76/452 (16%)
Query: 28 EDDKDKAKRVSRNKSEKKR------RDQFNVLIKELGSMLPGNAR---KMDKSTVLQKSI 78
+ D + +R+ + EK R R + N EL +LP A ++DK+++++ +I
Sbjct: 9 QQDPSRRERLQALRKEKSRDAARSRRGKENFEFYELAKLLPLPAAITSQLDKASIIRLTI 68
Query: 79 DFLRKHKEITAQSDAS-EIRQD-------------WK--------------------PTF 104
+L K ++ Q D +R + WK P+
Sbjct: 69 SYL-KMRDFANQGDPPWNLRMEGPPPNTSVKGIQMWKSELCMRKTPCEVIGAQRRRSPSA 127
Query: 105 LSNEEFTQLM----LEALDGFFLAIMTDGSIIYVSESVTSLLEHLPSDLVDQSIFNFIPE 160
L+ E F + L++LDGF A+ +G +Y+SE+V+ L +L S+F+++
Sbjct: 128 LAIEVFEAHLGSHILQSLDGFVFALNQEGKFLYISETVSIYLGLSQVELTGSSVFDYVHP 187
Query: 161 GEHSEVYKILSTHLLESDSLTPEYLKSKNQLEFCCHMLRGTIDPKEPS---------TYE 211
G+H E+ + L L L + T +P E + T E
Sbjct: 188 GDHVEMAEQLGMKLPPGRGLLSQGTAEDGASSASSSSQSETPEPVESTSPSLLTTDNTLE 247
Query: 212 YVKFIGNFKSLNS----VSSSAHNGFEGT------IQRTHRPSYEDRVCFVATVRLATPQ 261
FI +L + SS + T + +H + ++ + V A P
Sbjct: 248 RSFFIRMKSTLTKRGVHIKSSGYKVIHITGRLRLRVSLSHGRTVPSQIMGLVVVAHALPP 307
Query: 262 FIKEMCTVEEPNEE---FTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHVDDL 318
T+ E + F +R +++ ++ ++R + P +++G Y + H +D+
Sbjct: 308 -----PTINEVRIDCHMFVTRVNMDLNIIYCENRISDYMDLTPVDIVGKRCYHFIHAEDV 362
Query: 319 ENLAKCHEHLMQYGKGKSCYYRFLTKGQQWIWLQTHYYITYHQWNSRPEFIVCTHTVVSY 378
E + H L+ G+ + YYR++ K +IW+Q+ I + N+ + I+ + ++S
Sbjct: 363 EGIRHSHLDLLNKGQCVTKYYRWMQKNGGYIWIQSSATIAINAKNANEKNIIWVNYLLSN 422
Query: 379 AEVRAERRRELGIEESLPETAADKSQDSGSDN 410
E + + ++ LPE ++ S+ S S++
Sbjct: 423 PEYK-DTPMDIAQLPHLPEKTSESSETSDSES 453
>gi|22027482 neuronal PAS domain protein 1 [Homo sapiens]
Length = 590
Score = 80.5 bits (197), Expect = 6e-15
Identities = 103/461 (22%), Positives = 183/461 (39%), Gaps = 46/461 (9%)
Query: 35 KRVSRNKSEKKRRDQFNVLIKELGSMLP---GNARKMDKSTVLQKSIDFLRKHKEITAQS 91
K SRN + + RR + N+ EL +LP + ++DK+++++ S+ +LR + +
Sbjct: 47 KEKSRNAA-RSRRGKENLEFFELAKLLPLPGAISSQLDKASIVRLSVTYLRLRRFAALGA 105
Query: 92 DASEIRQDWKPTFLS----------NEEFTQLM----LEALDGFFLAIMTDGSIIYVSES 137
+R P L+ +E F Q + L++LDGF A+ +G +Y+SE+
Sbjct: 106 PPWGLRAAGPPAGLAPGRRGPAALVSEVFEQHLGGHILQSLDGFVFALNQEGKFLYISET 165
Query: 138 VTSLLEHLPSDLVDQSIFNFIPEGEHSEVYKILSTHLLESDSLTPEYLKSKNQLEFC--- 194
V+ L ++ S+F++I G+HSEV + L TP + S +
Sbjct: 166 VSIYLGLSQVEMTGSSVFDYIHPGDHSEVLEQLGLRTPTPGPPTPPSVSSSSSSSSSLAD 225
Query: 195 CHMLRGTIDPKEPSTYEYVKFIGNFKSLNSVSSSAHNGFEGTIQRTHRPSYEDRVCFVAT 254
+ ++ PS+ V+ F + S + + + + + R +
Sbjct: 226 TPEIEASLTKVPPSS--LVQERSFFVRMKSTLTKRGLHVKASGYKVIHVTGRLRAHALGL 283
Query: 255 VRLATPQFIKEMCTVEEPNEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYH 314
V L + + R SL L + R + P E++G S Y + H
Sbjct: 284 VALGHTLPPAPLAELPLHGHMIVFRLSLGLTILACESRVSDHMDLGPSELVGRSCYQFVH 343
Query: 315 VDDLENLAKCHEHLMQYGKGKSCYYRFLTKGQQWIWLQTHYYITYHQWNSRPEFIVCTHT 374
D + + H L+ G+ + YYR+L + ++WLQ+ + + ++
Sbjct: 344 GQDATRIRQSHVDLLDKGQVMTGYYRWLQRAGGFVWLQSVATVAGSGKSPGEHHVLWVSH 403
Query: 375 VVSYAE--------------VRAERRRELGIEESLPETAADKSQDSGSDNRINTVSLKEA 420
V+S AE V E G E + PE + Q + ++N K
Sbjct: 404 VLSQAEGGQTPLDAFQLPASVACEEASSPGPEPTEPEPPTEGKQAAPAENEAPQTQGK-- 461
Query: 421 LERFDHSPTPSASSRSSRKSSHTAVSDPSSTP-TKIPTDTS 460
R P P R ++ S + DPSS P T P TS
Sbjct: 462 --RIKVEPGP----RETKGSEDSGDEDPSSHPATPRPEFTS 496
>gi|32307126 nuclear receptor coactivator 3 isoform a [Homo sapiens]
Length = 1424
Score = 78.6 bits (192), Expect = 2e-14
Identities = 53/171 (30%), Positives = 88/171 (51%), Gaps = 13/171 (7%)
Query: 43 EKKRRDQFNVLIKELGSMLPGNAR-------KMDKSTVLQKSIDFLRKHKEI--TAQSDA 93
EK+RR+Q + I+EL ++ N K DK +L++++ +R+ KE T +D
Sbjct: 34 EKRRREQESKYIEELAELISANLSDIDNFNVKPDKCAILKETVRQIRQIKEQGKTISNDD 93
Query: 94 SEIRQDWKPT---FLSNEEFTQLMLEALDGFFLAIMTDGSIIYVSESVTSLLEHLPSDLV 150
+ D T + + L+L+ALDGF + DG+I++VSE+VT L++ DLV
Sbjct: 94 DVQKADVSSTGQGVIDKDSLGPLLLQALDGFLFVVNRDGNIVFVSENVTQYLQYKQEDLV 153
Query: 151 DQSIFNFIPEGEHSEVYKILSTHLLESDSLTPEYLKSKNQLEFCCHMLRGT 201
+ S++N + E + + K L + S T E + K+ F C ML T
Sbjct: 154 NTSVYNILHEEDRKDFLKNLPKSTVNGVSWTNETQRQKSH-TFNCRMLMKT 203
Score = 39.3 bits (90), Expect = 0.016
Identities = 51/256 (19%), Positives = 96/256 (37%), Gaps = 11/256 (4%)
Query: 426 HSPTPSASSRSSRKSSHTAVSDPSSTPTKIPTDTSTPPRQH---LPAHEKMVQRRSSFSS 482
HS ++ SS K S +V+ PS + S+ H L +++ + +
Sbjct: 634 HSSLTNSPLDSSCKESSVSVTSPSGVSSSTSGGVSSTSNMHGSLLQEKHRILHKLLQNGN 693
Query: 483 QSINSQSVGSSLTQPVMSQATNLPIPQGMSQFQFSAQLGAMQHLKDQLEQRTRMIEANIH 542
+ + T S T+ + Q Q S + L L R +A
Sbjct: 694 SPAEVAKITAEATGKDTSSITSCGDGNVVKQEQLSPKKKENNALLRYLLDRDDPSDALSK 753
Query: 543 RQQEELRKIQEQLQMVHGQGLQMFLQQSNPGLNFGSVQLSSGNSSNIQQLAPINMQGQVV 602
Q ++ + ++ + Q+ +P + + + SG+ N+ + ++
Sbjct: 754 ELQPQVEGVDNKMSQCTSSTIPSSSQEKDPKIKTETSEEGSGDLDNLDAILG-DLTSSDF 812
Query: 603 PTNQIQSGMNTGHIGTTQHMIQ-QQTLQSTSTQSQQNVLSGHSQQTSLPSQTQSTLTAPL 661
N I S N H+GT Q + Q +L S+QS Q++ +++ SL S + P+
Sbjct: 813 YNNSISS--NGSHLGTKQQVFQGTNSLGLKSSQSVQSIRPPYNRAVSLDSPVSVGSSPPV 870
Query: 662 YN----TMVISQPAAG 673
N M+ QP G
Sbjct: 871 KNISAFPMLPKQPMLG 886
Score = 38.5 bits (88), Expect = 0.026
Identities = 29/97 (29%), Positives = 41/97 (42%), Gaps = 11/97 (11%)
Query: 745 QQQSQTLSVTQQQQQQSSQEQQLTSVQQPSQAQLTQPPQQFLQTSRLLHGNPSTQLILSA 804
+QQ + + QQQQQQ Q+QQ QQ Q Q Q Q + +PS +L+
Sbjct: 1239 RQQRVAMMMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAG 1298
Query: 805 AFPLQQSTFPQSHHQQHQSQQQQQLSRHRTDSLPDPS 841
T PQ+ QQ Q + + PDP+
Sbjct: 1299 ------PTMPQAPPQQFPYQPNYGMGQQ-----PDPA 1324
Score = 33.1 bits (74), Expect = 1.1
Identities = 61/283 (21%), Positives = 96/283 (33%), Gaps = 35/283 (12%)
Query: 508 PQGMSQFQFSAQLGAMQHLKDQLEQRTRMIEANIHRQQEELR---KIQEQLQMVHGQGLQ 564
P F Q + + +Q+ Q+ +H + +R +QL+M Q LQ
Sbjct: 1120 PPMQGGFHLQGQSPSFNSMMNQMNQQGNFPLQGMHPRANIMRPRTNTPKQLRMQLQQRLQ 1179
Query: 565 --MFLQQSNPGLNFGSVQLSSGNSSNIQQLAPINMQGQVVPTNQIQSGMNTGHIGTTQH- 621
FL QS L ++G ++ ++ + + Q N + + + H
Sbjct: 1180 GQQFLNQSRQALELKMENPTAGGAAVMRPMMQPQVSSQQGFLNAQMVAQRSREL-LSHHF 1238
Query: 622 -------MIQQQTLQSTSTQSQQNVLSGHSQQTSLPSQTQSTLTAPLYNTMVISQPAAGS 674
M+QQQ Q Q QQ QQ QTQ+ P V + P+
Sbjct: 1239 RQQRVAMMMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQAFSPPP----NVTASPSMDG 1294
Query: 675 MVQIPSSMPQNSTQSAAVTTFTQDRQIRFSQGQQLVTKLVTAPVACGAVMVPSTMLMGQV 734
++ P +MPQ Q Q + GQQ A G V P +M
Sbjct: 1295 LLAGP-TMPQAPPQQFPY-------QPNYGMGQQ-------PDPAFGRVSSPPNAMMSSR 1339
Query: 735 VTAYPTFATQQQQSQTLSVTQQQQQQSSQEQQLTSVQQPSQAQ 777
+ P+ Q Q S+ Q + + L SQ Q
Sbjct: 1340 MG--PSQNPMMQHPQAASIYQSSEMKGWPSGNLARNSSFSQQQ 1380
>gi|32307124 nuclear receptor coactivator 3 isoform b [Homo sapiens]
Length = 1420
Score = 78.6 bits (192), Expect = 2e-14
Identities = 53/171 (30%), Positives = 88/171 (51%), Gaps = 13/171 (7%)
Query: 43 EKKRRDQFNVLIKELGSMLPGNAR-------KMDKSTVLQKSIDFLRKHKEI--TAQSDA 93
EK+RR+Q + I+EL ++ N K DK +L++++ +R+ KE T +D
Sbjct: 34 EKRRREQESKYIEELAELISANLSDIDNFNVKPDKCAILKETVRQIRQIKEQGKTISNDD 93
Query: 94 SEIRQDWKPT---FLSNEEFTQLMLEALDGFFLAIMTDGSIIYVSESVTSLLEHLPSDLV 150
+ D T + + L+L+ALDGF + DG+I++VSE+VT L++ DLV
Sbjct: 94 DVQKADVSSTGQGVIDKDSLGPLLLQALDGFLFVVNRDGNIVFVSENVTQYLQYKQEDLV 153
Query: 151 DQSIFNFIPEGEHSEVYKILSTHLLESDSLTPEYLKSKNQLEFCCHMLRGT 201
+ S++N + E + + K L + S T E + K+ F C ML T
Sbjct: 154 NTSVYNILHEEDRKDFLKNLPKSTVNGVSWTNETQRQKSH-TFNCRMLMKT 203
Score = 39.3 bits (90), Expect = 0.016
Identities = 51/256 (19%), Positives = 96/256 (37%), Gaps = 11/256 (4%)
Query: 426 HSPTPSASSRSSRKSSHTAVSDPSSTPTKIPTDTSTPPRQH---LPAHEKMVQRRSSFSS 482
HS ++ SS K S +V+ PS + S+ H L +++ + +
Sbjct: 634 HSSLTNSPLDSSCKESSVSVTSPSGVSSSTSGGVSSTSNMHGSLLQEKHRILHKLLQNGN 693
Query: 483 QSINSQSVGSSLTQPVMSQATNLPIPQGMSQFQFSAQLGAMQHLKDQLEQRTRMIEANIH 542
+ + T S T+ + Q Q S + L L R +A
Sbjct: 694 SPAEVAKITAEATGKDTSSITSCGDGNVVKQEQLSPKKKENNALLRYLLDRDDPSDALSK 753
Query: 543 RQQEELRKIQEQLQMVHGQGLQMFLQQSNPGLNFGSVQLSSGNSSNIQQLAPINMQGQVV 602
Q ++ + ++ + Q+ +P + + + SG+ N+ + ++
Sbjct: 754 ELQPQVEGVDNKMSQCTSSTIPSSSQEKDPKIKTETSEEGSGDLDNLDAILG-DLTSSDF 812
Query: 603 PTNQIQSGMNTGHIGTTQHMIQ-QQTLQSTSTQSQQNVLSGHSQQTSLPSQTQSTLTAPL 661
N I S N H+GT Q + Q +L S+QS Q++ +++ SL S + P+
Sbjct: 813 YNNSISS--NGSHLGTKQQVFQGTNSLGLKSSQSVQSIRPPYNRAVSLDSPVSVGSSPPV 870
Query: 662 YN----TMVISQPAAG 673
N M+ QP G
Sbjct: 871 KNISAFPMLPKQPMLG 886
Score = 38.5 bits (88), Expect = 0.026
Identities = 29/97 (29%), Positives = 41/97 (42%), Gaps = 11/97 (11%)
Query: 745 QQQSQTLSVTQQQQQQSSQEQQLTSVQQPSQAQLTQPPQQFLQTSRLLHGNPSTQLILSA 804
+QQ + + QQQQQQ Q+QQ QQ Q Q Q Q + +PS +L+
Sbjct: 1235 RQQRVAMMMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAG 1294
Query: 805 AFPLQQSTFPQSHHQQHQSQQQQQLSRHRTDSLPDPS 841
T PQ+ QQ Q + + PDP+
Sbjct: 1295 ------PTMPQAPPQQFPYQPNYGMGQQ-----PDPA 1320
Score = 33.5 bits (75), Expect = 0.85
Identities = 60/278 (21%), Positives = 95/278 (34%), Gaps = 29/278 (10%)
Query: 508 PQGMSQFQFSAQLGAMQHLKDQLEQRTRMIEANIHRQQEELR---KIQEQLQMVHGQGLQ 564
P F Q + + +Q+ Q+ +H + +R +QL+M Q LQ
Sbjct: 1120 PPMQGGFHLQGQSPSFNSMMNQMNQQGNFPLQGMHPRANIMRPRTNTPKQLRMQLQQRLQ 1179
Query: 565 --MFLQQSNPGLNFGSVQLSSGNSSNIQQLAPIN---MQGQVVPTNQIQSGMNTGHIGTT 619
FL QS L ++G ++ ++ + + Q+V + +
Sbjct: 1180 GQQFLNQSRQALELKMENPTAGGAAVMRPMMQPQQGFLNAQMVAQRSRELLSHHFRQQRV 1239
Query: 620 QHMIQQQTLQSTSTQSQQNVLSGHSQQTSLPSQTQSTLTAPLYNTMVISQPAAGSMVQIP 679
M+QQQ Q Q QQ QQ QTQ+ P V + P+ ++ P
Sbjct: 1240 AMMMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQAFSPPP----NVTASPSMDGLLAGP 1295
Query: 680 SSMPQNSTQSAAVTTFTQDRQIRFSQGQQLVTKLVTAPVACGAVMVPSTMLMGQVVTAYP 739
+MPQ Q Q + GQQ A G V P +M + P
Sbjct: 1296 -TMPQAPPQQFPY-------QPNYGMGQQ-------PDPAFGRVSSPPNAMMSSRMG--P 1338
Query: 740 TFATQQQQSQTLSVTQQQQQQSSQEQQLTSVQQPSQAQ 777
+ Q Q S+ Q + + L SQ Q
Sbjct: 1339 SQNPMMQHPQAASIYQSSEMKGWPSGNLARNSSFSQQQ 1376
>gi|30795240 aryl hydrocarbon receptor nuclear translocator isoform
2 [Homo sapiens]
Length = 328
Score = 73.6 bits (179), Expect = 7e-13
Identities = 45/148 (30%), Positives = 84/148 (56%), Gaps = 10/148 (6%)
Query: 30 DKDKAKRVSRNKSEKKRRDQFNVLIKELGSMLP---GNARKMDKSTVLQKSIDFLRKHKE 86
DK++ R + ++ E++RR++ I EL M+P ARK DK T+L+ ++ ++ +
Sbjct: 85 DKERLARENHSEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVSHMKSLRG 144
Query: 87 I-TAQSDASEIRQDWKPTFLSNEEFTQLMLEALDGF-FLAIMTDGSIIYVSESVTSLLEH 144
+D S +KP+FL+++E L+LEA DGF F+ G ++YVS+SVT +L
Sbjct: 145 TGNTSTDGS-----YKPSFLTDQELKHLILEAADGFLFIVSCETGRVVYVSDSVTPVLNQ 199
Query: 145 LPSDLVDQSIFNFIPEGEHSEVYKILST 172
S+ ++++ + + ++ + LST
Sbjct: 200 PQSEWFGSTLYDQVHPDDVDKLREQLST 227
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.126 0.356
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,752,163
Number of Sequences: 37866
Number of extensions: 1379044
Number of successful extensions: 14619
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 156
Number of HSP's successfully gapped in prelim test: 339
Number of HSP's that attempted gapping in prelim test: 8993
Number of HSP's gapped (non-prelim): 3129
length of query: 846
length of database: 18,247,518
effective HSP length: 111
effective length of query: 735
effective length of database: 14,044,392
effective search space: 10322628120
effective search space used: 10322628120
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.