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Search of human proteins with 47419909
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|47419909 transcriptional intermediary factor 1 alpha isoform
b [Homo sapiens]
(1016 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|47419909 transcriptional intermediary factor 1 alpha isoform ... 2077 0.0
gi|47419911 transcriptional intermediary factor 1 alpha isoform ... 2060 0.0
gi|74027251 tripartite motif-containing 33 protein isoform beta ... 939 0.0
gi|74027249 tripartite motif-containing 33 protein isoform alpha... 928 0.0
gi|5032179 tripartite motif-containing 28 protein [Homo sapiens] 310 6e-84
gi|209977097 tripartite motif-containing 66 [Homo sapiens] 246 1e-64
gi|224548923 tripartite motif-containing 45 isoform 2 [Homo sapi... 128 2e-29
gi|224548921 tripartite motif-containing 45 isoform 1 [Homo sapi... 128 2e-29
gi|84993742 tripartite motif-containing 71 [Homo sapiens] 108 3e-23
gi|190343006 SP110 nuclear body protein isoform c [Homo sapiens] 104 5e-22
gi|134133279 SP140 nuclear body protein-like [Homo sapiens] 102 1e-21
gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo... 101 3e-21
gi|217330601 SP140 nuclear body protein isoform 1 [Homo sapiens] 101 4e-21
gi|122939208 nuclear antigen Sp100 isoform 1 [Homo sapiens] 100 1e-20
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 97 8e-20
gi|34335264 zinc finger, MYND-type containing 8 isoform c [Homo ... 91 6e-18
gi|34335262 zinc finger, MYND-type containing 8 isoform a [Homo ... 89 2e-17
gi|34335266 zinc finger, MYND-type containing 8 isoform b [Homo ... 89 2e-17
gi|67089160 promyelocytic leukemia protein isoform 11 [Homo sapi... 86 2e-16
gi|119943102 CREB binding protein isoform b [Homo sapiens] 85 4e-16
gi|119943104 CREB binding protein isoform a [Homo sapiens] 85 4e-16
gi|32454739 tripartite motif-containing 3 [Homo sapiens] 85 4e-16
gi|32454737 tripartite motif-containing 3 [Homo sapiens] 85 4e-16
gi|194248081 tripartite motif-containing 2 isoform 2 [Homo sapiens] 84 7e-16
gi|194248079 tripartite motif-containing 2 isoform 1 [Homo sapiens] 84 7e-16
gi|38788260 bromodomain PHD finger transcription factor isoform ... 82 2e-15
gi|38788274 bromodomain PHD finger transcription factor isoform ... 82 2e-15
gi|30794216 tripartite motif-containing 56 [Homo sapiens] 82 3e-15
gi|15451779 promyelocytic leukemia protein isoform 10 [Homo sapi... 79 2e-14
gi|67089157 promyelocytic leukemia protein isoform 2 [Homo sapiens] 79 2e-14
>gi|47419909 transcriptional intermediary factor 1 alpha isoform b
[Homo sapiens]
Length = 1016
Score = 2077 bits (5381), Expect = 0.0
Identities = 1016/1016 (100%), Positives = 1016/1016 (100%)
Query: 1 MEVAVEKAVAAAAAASAAASGGPSAAPSGENEAESRQGPDSERGGEAARLNLLDTCAVCH 60
MEVAVEKAVAAAAAASAAASGGPSAAPSGENEAESRQGPDSERGGEAARLNLLDTCAVCH
Sbjct: 1 MEVAVEKAVAAAAAASAAASGGPSAAPSGENEAESRQGPDSERGGEAARLNLLDTCAVCH 60
Query: 61 QNIQSRAPKLLPCLHSFCQRCLPAPQRYLMLPAPMLGSAETPPPVPAPGSPVSGSSPFAT 120
QNIQSRAPKLLPCLHSFCQRCLPAPQRYLMLPAPMLGSAETPPPVPAPGSPVSGSSPFAT
Sbjct: 61 QNIQSRAPKLLPCLHSFCQRCLPAPQRYLMLPAPMLGSAETPPPVPAPGSPVSGSSPFAT 120
Query: 121 QVGVIRCPVCSQECAERHIIDNFFVKDTTEVPSSTVEKSNQVCTSCEDNAEANGFCVECV 180
QVGVIRCPVCSQECAERHIIDNFFVKDTTEVPSSTVEKSNQVCTSCEDNAEANGFCVECV
Sbjct: 121 QVGVIRCPVCSQECAERHIIDNFFVKDTTEVPSSTVEKSNQVCTSCEDNAEANGFCVECV 180
Query: 181 EWLCKTCIRAHQRVKFTKDHTVRQKEEVSPEAVGVTSQRPVFCPFHKKEQLKLYCETCDK 240
EWLCKTCIRAHQRVKFTKDHTVRQKEEVSPEAVGVTSQRPVFCPFHKKEQLKLYCETCDK
Sbjct: 181 EWLCKTCIRAHQRVKFTKDHTVRQKEEVSPEAVGVTSQRPVFCPFHKKEQLKLYCETCDK 240
Query: 241 LTCRDCQLLEHKEHRYQFIEEAFQNQKVIIDTLITKLMEKTKYIKFTGNQIQNRIIEVNQ 300
LTCRDCQLLEHKEHRYQFIEEAFQNQKVIIDTLITKLMEKTKYIKFTGNQIQNRIIEVNQ
Sbjct: 241 LTCRDCQLLEHKEHRYQFIEEAFQNQKVIIDTLITKLMEKTKYIKFTGNQIQNRIIEVNQ 300
Query: 301 NQKQVEQDIKVAIFTLMVEINKKGKALLHQLESLAKDHRMKLMQQQQEVAGLSKQLEHVM 360
NQKQVEQDIKVAIFTLMVEINKKGKALLHQLESLAKDHRMKLMQQQQEVAGLSKQLEHVM
Sbjct: 301 NQKQVEQDIKVAIFTLMVEINKKGKALLHQLESLAKDHRMKLMQQQQEVAGLSKQLEHVM 360
Query: 361 HFSKWAVSSGSSTALLYSKRLITYRLRHLLRARCDASPVTNNTIQFHCDPSFWAQNIINL 420
HFSKWAVSSGSSTALLYSKRLITYRLRHLLRARCDASPVTNNTIQFHCDPSFWAQNIINL
Sbjct: 361 HFSKWAVSSGSSTALLYSKRLITYRLRHLLRARCDASPVTNNTIQFHCDPSFWAQNIINL 420
Query: 421 GSLVIEDKESQPQMPKQNPVVEQNSQPPSGLSSNQLSKFPTQISLAQLRLQHMQQQQPPP 480
GSLVIEDKESQPQMPKQNPVVEQNSQPPSGLSSNQLSKFPTQISLAQLRLQHMQQQQPPP
Sbjct: 421 GSLVIEDKESQPQMPKQNPVVEQNSQPPSGLSSNQLSKFPTQISLAQLRLQHMQQQQPPP 480
Query: 481 RLINFQNHSPKPNGPVLPPHPQQLRYPPNQNIPRQAIKPNPLQMAFLAQQAIKQWQISSG 540
RLINFQNHSPKPNGPVLPPHPQQLRYPPNQNIPRQAIKPNPLQMAFLAQQAIKQWQISSG
Sbjct: 481 RLINFQNHSPKPNGPVLPPHPQQLRYPPNQNIPRQAIKPNPLQMAFLAQQAIKQWQISSG 540
Query: 541 QGTPSTTNSTSSTPSSPTITSAAGYDGKAFGSPMIDLSSPVGGSYNLPSLPDIDCSSTIM 600
QGTPSTTNSTSSTPSSPTITSAAGYDGKAFGSPMIDLSSPVGGSYNLPSLPDIDCSSTIM
Sbjct: 541 QGTPSTTNSTSSTPSSPTITSAAGYDGKAFGSPMIDLSSPVGGSYNLPSLPDIDCSSTIM 600
Query: 601 LDNIVRKDTNIDHGQPRPPSNRTVQSPNSSVPSPGLAGPVTMTSVHPPIRSPSASSVGSR 660
LDNIVRKDTNIDHGQPRPPSNRTVQSPNSSVPSPGLAGPVTMTSVHPPIRSPSASSVGSR
Sbjct: 601 LDNIVRKDTNIDHGQPRPPSNRTVQSPNSSVPSPGLAGPVTMTSVHPPIRSPSASSVGSR 660
Query: 661 GSSGSSSKPAGADSTHKVPVVMLEPIRIKQENSGPPENYDFPVVIVKQESDEESRPQNAN 720
GSSGSSSKPAGADSTHKVPVVMLEPIRIKQENSGPPENYDFPVVIVKQESDEESRPQNAN
Sbjct: 661 GSSGSSSKPAGADSTHKVPVVMLEPIRIKQENSGPPENYDFPVVIVKQESDEESRPQNAN 720
Query: 721 YPRSILTSLLLNSSQSSTSEETVLRSDAPDSTGDQPGLHQDNSSNGKSEWLDPSQKSPLH 780
YPRSILTSLLLNSSQSSTSEETVLRSDAPDSTGDQPGLHQDNSSNGKSEWLDPSQKSPLH
Sbjct: 721 YPRSILTSLLLNSSQSSTSEETVLRSDAPDSTGDQPGLHQDNSSNGKSEWLDPSQKSPLH 780
Query: 781 VGETRKEDDPNEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLS 840
VGETRKEDDPNEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLS
Sbjct: 781 VGETRKEDDPNEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLS 840
Query: 841 KPEVEYDCDAPSHNSEKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTVPD 900
KPEVEYDCDAPSHNSEKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTVPD
Sbjct: 841 KPEVEYDCDAPSHNSEKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTVPD 900
Query: 901 YYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLE 960
YYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLE
Sbjct: 901 YYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLE 960
Query: 961 NYFEELLKNLYPEKRFPKPEFRNESEDNKFSDDSDDDFVQPRKKRLKSIEERQLLK 1016
NYFEELLKNLYPEKRFPKPEFRNESEDNKFSDDSDDDFVQPRKKRLKSIEERQLLK
Sbjct: 961 NYFEELLKNLYPEKRFPKPEFRNESEDNKFSDDSDDDFVQPRKKRLKSIEERQLLK 1016
>gi|47419911 transcriptional intermediary factor 1 alpha isoform a
[Homo sapiens]
Length = 1050
Score = 2060 bits (5336), Expect = 0.0
Identities = 1016/1050 (96%), Positives = 1016/1050 (96%), Gaps = 34/1050 (3%)
Query: 1 MEVAVEKAVAAAAAASAAASGGPSAAPSGENEAESRQGPDSERGGEAARLNLLDTCAVCH 60
MEVAVEKAVAAAAAASAAASGGPSAAPSGENEAESRQGPDSERGGEAARLNLLDTCAVCH
Sbjct: 1 MEVAVEKAVAAAAAASAAASGGPSAAPSGENEAESRQGPDSERGGEAARLNLLDTCAVCH 60
Query: 61 QNIQSRAPKLLPCLHSFCQRCLPAPQRYLMLPAPMLGSAETPPPVPAPGSPVSGSSPFAT 120
QNIQSRAPKLLPCLHSFCQRCLPAPQRYLMLPAPMLGSAETPPPVPAPGSPVSGSSPFAT
Sbjct: 61 QNIQSRAPKLLPCLHSFCQRCLPAPQRYLMLPAPMLGSAETPPPVPAPGSPVSGSSPFAT 120
Query: 121 QVGVIRCPVCSQECAERHIIDNFFVKDTTEVPSSTVEKSNQVCTSCEDNAEANGFCVECV 180
QVGVIRCPVCSQECAERHIIDNFFVKDTTEVPSSTVEKSNQVCTSCEDNAEANGFCVECV
Sbjct: 121 QVGVIRCPVCSQECAERHIIDNFFVKDTTEVPSSTVEKSNQVCTSCEDNAEANGFCVECV 180
Query: 181 EWLCKTCIRAHQRVKFTKDHTVRQKEEVSPEAVGVTSQRPVFCPFHKKEQLKLYCETCDK 240
EWLCKTCIRAHQRVKFTKDHTVRQKEEVSPEAVGVTSQRPVFCPFHKKEQLKLYCETCDK
Sbjct: 181 EWLCKTCIRAHQRVKFTKDHTVRQKEEVSPEAVGVTSQRPVFCPFHKKEQLKLYCETCDK 240
Query: 241 LTCRDCQLLEHKEHRYQFIEEAFQNQKVIIDTLITKLMEKTKYIKFTGNQIQNRIIEVNQ 300
LTCRDCQLLEHKEHRYQFIEEAFQNQKVIIDTLITKLMEKTKYIKFTGNQIQNRIIEVNQ
Sbjct: 241 LTCRDCQLLEHKEHRYQFIEEAFQNQKVIIDTLITKLMEKTKYIKFTGNQIQNRIIEVNQ 300
Query: 301 NQKQVEQDIKVAIFTLMVEINKKGKALLHQLESLAKDHRMKLMQQQQEVAGLSKQLEHVM 360
NQKQVEQDIKVAIFTLMVEINKKGKALLHQLESLAKDHRMKLMQQQQEVAGLSKQLEHVM
Sbjct: 301 NQKQVEQDIKVAIFTLMVEINKKGKALLHQLESLAKDHRMKLMQQQQEVAGLSKQLEHVM 360
Query: 361 HFSKWAVSSGSSTALLYSKRLITYRLRHLLRARCDASPVTNNTIQFHCDPSFWAQNIINL 420
HFSKWAVSSGSSTALLYSKRLITYRLRHLLRARCDASPVTNNTIQFHCDPSFWAQNIINL
Sbjct: 361 HFSKWAVSSGSSTALLYSKRLITYRLRHLLRARCDASPVTNNTIQFHCDPSFWAQNIINL 420
Query: 421 GSLVIEDKESQPQMPKQNPVVEQNSQPPSGLSSNQLSKFPTQISLAQLRLQHMQQQ---- 476
GSLVIEDKESQPQMPKQNPVVEQNSQPPSGLSSNQLSKFPTQISLAQLRLQHMQQQ
Sbjct: 421 GSLVIEDKESQPQMPKQNPVVEQNSQPPSGLSSNQLSKFPTQISLAQLRLQHMQQQVMAQ 480
Query: 477 ------------------------------QPPPRLINFQNHSPKPNGPVLPPHPQQLRY 506
QPPPRLINFQNHSPKPNGPVLPPHPQQLRY
Sbjct: 481 RQQVQRRPAPVGLPNPRMQGPIQQPSISHQQPPPRLINFQNHSPKPNGPVLPPHPQQLRY 540
Query: 507 PPNQNIPRQAIKPNPLQMAFLAQQAIKQWQISSGQGTPSTTNSTSSTPSSPTITSAAGYD 566
PPNQNIPRQAIKPNPLQMAFLAQQAIKQWQISSGQGTPSTTNSTSSTPSSPTITSAAGYD
Sbjct: 541 PPNQNIPRQAIKPNPLQMAFLAQQAIKQWQISSGQGTPSTTNSTSSTPSSPTITSAAGYD 600
Query: 567 GKAFGSPMIDLSSPVGGSYNLPSLPDIDCSSTIMLDNIVRKDTNIDHGQPRPPSNRTVQS 626
GKAFGSPMIDLSSPVGGSYNLPSLPDIDCSSTIMLDNIVRKDTNIDHGQPRPPSNRTVQS
Sbjct: 601 GKAFGSPMIDLSSPVGGSYNLPSLPDIDCSSTIMLDNIVRKDTNIDHGQPRPPSNRTVQS 660
Query: 627 PNSSVPSPGLAGPVTMTSVHPPIRSPSASSVGSRGSSGSSSKPAGADSTHKVPVVMLEPI 686
PNSSVPSPGLAGPVTMTSVHPPIRSPSASSVGSRGSSGSSSKPAGADSTHKVPVVMLEPI
Sbjct: 661 PNSSVPSPGLAGPVTMTSVHPPIRSPSASSVGSRGSSGSSSKPAGADSTHKVPVVMLEPI 720
Query: 687 RIKQENSGPPENYDFPVVIVKQESDEESRPQNANYPRSILTSLLLNSSQSSTSEETVLRS 746
RIKQENSGPPENYDFPVVIVKQESDEESRPQNANYPRSILTSLLLNSSQSSTSEETVLRS
Sbjct: 721 RIKQENSGPPENYDFPVVIVKQESDEESRPQNANYPRSILTSLLLNSSQSSTSEETVLRS 780
Query: 747 DAPDSTGDQPGLHQDNSSNGKSEWLDPSQKSPLHVGETRKEDDPNEDWCAVCQNGGELLC 806
DAPDSTGDQPGLHQDNSSNGKSEWLDPSQKSPLHVGETRKEDDPNEDWCAVCQNGGELLC
Sbjct: 781 DAPDSTGDQPGLHQDNSSNGKSEWLDPSQKSPLHVGETRKEDDPNEDWCAVCQNGGELLC 840
Query: 807 CEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDAPSHNSEKKKTEGLVKL 866
CEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDAPSHNSEKKKTEGLVKL
Sbjct: 841 CEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDAPSHNSEKKKTEGLVKL 900
Query: 867 TPIDKRKCERLLLFLYCHEMSLAFQDPVPLTVPDYYKIIKNPMDLSTIKKRLQEDYSMYS 926
TPIDKRKCERLLLFLYCHEMSLAFQDPVPLTVPDYYKIIKNPMDLSTIKKRLQEDYSMYS
Sbjct: 901 TPIDKRKCERLLLFLYCHEMSLAFQDPVPLTVPDYYKIIKNPMDLSTIKKRLQEDYSMYS 960
Query: 927 KPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLENYFEELLKNLYPEKRFPKPEFRNESE 986
KPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLENYFEELLKNLYPEKRFPKPEFRNESE
Sbjct: 961 KPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLENYFEELLKNLYPEKRFPKPEFRNESE 1020
Query: 987 DNKFSDDSDDDFVQPRKKRLKSIEERQLLK 1016
DNKFSDDSDDDFVQPRKKRLKSIEERQLLK
Sbjct: 1021 DNKFSDDSDDDFVQPRKKRLKSIEERQLLK 1050
>gi|74027251 tripartite motif-containing 33 protein isoform beta [Homo
sapiens]
Length = 1110
Score = 939 bits (2427), Expect = 0.0
Identities = 527/1079 (48%), Positives = 682/1079 (63%), Gaps = 112/1079 (10%)
Query: 3 VAVEKAVAAAAAASAAAS------GGPSAAPSGENEAESRQGPDSERGGEAARLNLLDTC 56
VA + +A AA+S AAS GG + P+ + GP S +LLDTC
Sbjct: 67 VAAASSGSAQAASSPAASVGTGVAGGAVSTPAPAPASAPAPGP-SAGPPPGPPASLLDTC 125
Query: 57 AVCHQNIQSRA---PKLLPCLHSFCQRCLPAPQRYLMLPAPMLGSAETPPPVPAPGSPVS 113
AVC Q++QSR PKLLPCLHSFC RCLP P+R L +P P
Sbjct: 126 AVCQQSLQSRREAEPKLLPCLHSFCLRCLPEPERQLSVPIP------------------G 167
Query: 114 GSSPFATQVGVIRCPVCSQECAERHIIDNFFVKDTTEVPSSTVEKSNQVCTSCEDNAEAN 173
GS+ QVGVIRCPVC QEC + ++DN+FVKDT+E PSS+ EKS QVCTSCEDNA A
Sbjct: 168 GSNGDIQQVGVIRCPVCRQECRQIDLVDNYFVKDTSEAPSSSDEKSEQVCTSCEDNASAV 227
Query: 174 GFCVECVEWLCKTCIRAHQRVKFTKDHTVRQKEEVSPEAVGVTSQRPVFCPFHKKEQLKL 233
GFCVEC EWLCKTCI AHQRVKFTKDH +R+KE+VS E+VG + QRPVFCP HK+EQLKL
Sbjct: 228 GFCVECGEWLCKTCIEAHQRVKFTKDHLIRKKEDVS-ESVGASGQRPVFCPVHKQEQLKL 286
Query: 234 YCETCDKLTCRDCQLLEHKEHRYQFIEEAFQNQKVIIDTLITKLMEKTKYIKFTGNQIQN 293
+CETCD+LTCRDCQLLEHKEHRYQF+EEAFQNQK I+ L+ KL+EK Y+ F Q+QN
Sbjct: 287 FCETCDRLTCRDCQLLEHKEHRYQFLEEAFQNQKGAIENLLAKLLEKKNYVHFAATQVQN 346
Query: 294 RIIEVNQNQKQVEQDIKVAIFTLMVEINKKGKALLHQLESLAKDHRMKLMQQQQEVAGLS 353
RI EVN+ K+VEQ+IKVAIFTL+ EINKKGK+LL QLE++ K+ +MKL+QQQ ++ GLS
Sbjct: 347 RIKEVNETNKRVEQEIKVAIFTLINEINKKGKSLLQQLENVTKERQMKLLQQQNDITGLS 406
Query: 354 KQLEHVMHFSKWAVSSGSSTALLYSKRLITYRLRHLLRARCDASPVTNNTIQFHCDPSFW 413
+Q++HVM+F+ WA++SGSSTALLYSKRLIT++LRH+L+ARCD P N I+FHCDP+FW
Sbjct: 407 RQVKHVMNFTNWAIASGSSTALLYSKRLITFQLRHILKARCDPVPAANGAIRFHCDPTFW 466
Query: 414 AQNIINLGSLVIEDKESQPQMPKQNPVVEQNSQPPSGLSSNQLSKFPTQISLAQLRLQHM 473
A+N++NLG+LVIE K + P P V PP +N +SK P QI+LAQLRLQHM
Sbjct: 467 AKNVVNLGNLVIESKPA----PGYTPNVVVGQVPPG---TNHISKTPGQINLAQLRLQHM 519
Query: 474 QQQ---------------QPP---PRLINFQNHSPKPNGPVL----PPHPQQLRYPPNQN 511
QQQ QPP P P+ P + PP ++ N
Sbjct: 520 QQQVYAQKHQQLQQMRMQQPPAPVPTTTTTTQQHPRQAAPQMLQQQPPRLISVQTMQRGN 579
Query: 512 IPRQAIKPNPLQMAFLA------------QQAIKQWQISSGQGTPS--------TTNSTS 551
+ A + + +++A A Q ++ Q + P + ++T+
Sbjct: 580 MNCGAFQAHQMRLAQNAARIPGIPRHSGPQYSMMQPHLQRQHSNPGHAGPFPVVSVHNTT 639
Query: 552 STPSSPTITSAAGYDGKAFGSPM---IDLSSPVGGSYNLPSLPDI-----DCSSTIMLDN 603
P+SPT + A + + SP I+L V NLPSLPDI + + + LDN
Sbjct: 640 INPTSPTTATMANAN-RGPTSPSVTAIELIPSVTNPENLPSLPDIPPIQLEDAGSSSLDN 698
Query: 604 IVRKDTNIDHGQPRPPSNRTVQSPNSSVPSPGLAGPVTMTSVHPPIRSPSASSVGSRGSS 663
++ + + H P+P S SP S SPG +G +++ H P+R PS SS GSRGS
Sbjct: 699 LLSRYISGSHLPPQPTSTMN-PSPGPSALSPGSSG---LSNSHTPVRPPSTSSTGSRGSC 754
Query: 664 GSSSKPAGADSTHKVPVVMLEPIRIKQENSGPPENYDFPVVIVKQESDEESR-------- 715
GSS + A S + +++KQE E F VKQE E+ R
Sbjct: 755 GSSGRTAEKTSLS----FKSDQVKVKQEPGTEDEICSFSGG-VKQEKTEDGRRSACMLSS 809
Query: 716 PQNANYPRSILTSLLLNSSQSS-TSEETVLRSDAPDSTGDQPGLHQDNSSNGKSEWLDPS 774
P+++ P + T+L L S + S E ++ + D + NGKS
Sbjct: 810 PESSLTP-PLSTNLHLESELDALASLENHVKIEPADMNESCKQSGLSSLVNGKSPIRSLM 868
Query: 775 QKSPLHVGE-TRKEDDPNEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWIC 833
+S G+ K+DDPNEDWCAVCQNGG+LLCCEKCPKVFHL+CHVPTL +FPSG+WIC
Sbjct: 869 HRSARIGGDGNNKDDDPNEDWCAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFPSGDWIC 928
Query: 834 TFCRDLSKPEVEYDCDAPSHNSEKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDP 893
TFCRD+ KPEVEYDCD H+ + K +GL +P+D+RKCERLLL+LYCHE+S+ FQ+P
Sbjct: 929 TFCRDIGKPEVEYDCDNLQHSKKGKTAQGL---SPVDQRKCERLLLYLYCHELSIEFQEP 985
Query: 894 VPLTVPDYYKIIKNPMDLSTIKKRLQEDYSM-YSKPEDFVADFRLIFQNCAEFNEPDSEV 952
VP ++P+YYKIIK PMDLST+KK+LQ+ +S Y P+DFVAD RLIF+NC FNE DSEV
Sbjct: 986 VPASIPNYYKIIKKPMDLSTVKKKLQKKHSQHYQIPDDFVADVRLIFKNCERFNEADSEV 1045
Query: 953 ANAGIKLENYFEELLKNLYPEKRF-PKPEFRNESEDNKFSDDSDDDFVQPRKKRLKSIE 1010
A AG + YFE+ L +Y ++ F P PEF E +D + ++DSD+DF+QPR+KRLKS E
Sbjct: 1046 AQAGKAVALYFEDKLTEIYSDRTFAPLPEFEQEEDDGEVTEDSDEDFIQPRRKRLKSDE 1104
>gi|74027249 tripartite motif-containing 33 protein isoform alpha
[Homo sapiens]
Length = 1127
Score = 928 bits (2399), Expect = 0.0
Identities = 527/1096 (48%), Positives = 682/1096 (62%), Gaps = 129/1096 (11%)
Query: 3 VAVEKAVAAAAAASAAAS------GGPSAAPSGENEAESRQGPDSERGGEAARLNLLDTC 56
VA + +A AA+S AAS GG + P+ + GP S +LLDTC
Sbjct: 67 VAAASSGSAQAASSPAASVGTGVAGGAVSTPAPAPASAPAPGP-SAGPPPGPPASLLDTC 125
Query: 57 AVCHQNIQSRA---PKLLPCLHSFCQRCLPAPQRYLMLPAPMLGSAETPPPVPAPGSPVS 113
AVC Q++QSR PKLLPCLHSFC RCLP P+R L +P P
Sbjct: 126 AVCQQSLQSRREAEPKLLPCLHSFCLRCLPEPERQLSVPIP------------------G 167
Query: 114 GSSPFATQVGVIRCPVCSQECAERHIIDNFFVKDTTEVPSSTVEKSNQVCTSCEDNAEAN 173
GS+ QVGVIRCPVC QEC + ++DN+FVKDT+E PSS+ EKS QVCTSCEDNA A
Sbjct: 168 GSNGDIQQVGVIRCPVCRQECRQIDLVDNYFVKDTSEAPSSSDEKSEQVCTSCEDNASAV 227
Query: 174 GFCVECVEWLCKTCIRAHQRVKFTKDHTVRQKEEVSPEAVGVTSQRPVFCPFHKKEQLKL 233
GFCVEC EWLCKTCI AHQRVKFTKDH +R+KE+VS E+VG + QRPVFCP HK+EQLKL
Sbjct: 228 GFCVECGEWLCKTCIEAHQRVKFTKDHLIRKKEDVS-ESVGASGQRPVFCPVHKQEQLKL 286
Query: 234 YCETCDKLTCRDCQLLEHKEHRYQFIEEAFQNQKVIIDTLITKLMEKTKYIKFTGNQIQN 293
+CETCD+LTCRDCQLLEHKEHRYQF+EEAFQNQK I+ L+ KL+EK Y+ F Q+QN
Sbjct: 287 FCETCDRLTCRDCQLLEHKEHRYQFLEEAFQNQKGAIENLLAKLLEKKNYVHFAATQVQN 346
Query: 294 RIIEVNQNQKQVEQDIKVAIFTLMVEINKKGKALLHQLESLAKDHRMKLMQQQQEVAGLS 353
RI EVN+ K+VEQ+IKVAIFTL+ EINKKGK+LL QLE++ K+ +MKL+QQQ ++ GLS
Sbjct: 347 RIKEVNETNKRVEQEIKVAIFTLINEINKKGKSLLQQLENVTKERQMKLLQQQNDITGLS 406
Query: 354 KQLEHVMHFSKWAVSSGSSTALLYSKRLITYRLRHLLRARCDASPVTNNTIQFHCDPSFW 413
+Q++HVM+F+ WA++SGSSTALLYSKRLIT++LRH+L+ARCD P N I+FHCDP+FW
Sbjct: 407 RQVKHVMNFTNWAIASGSSTALLYSKRLITFQLRHILKARCDPVPAANGAIRFHCDPTFW 466
Query: 414 AQNIINLGSLVIEDKESQPQMPKQNPVVEQNSQPPSGLSSNQLSKFPTQISLAQLRLQHM 473
A+N++NLG+LVIE K + P P V PP +N +SK P QI+LAQLRLQHM
Sbjct: 467 AKNVVNLGNLVIESKPA----PGYTPNVVVGQVPPG---TNHISKTPGQINLAQLRLQHM 519
Query: 474 QQQ---------------QPP---PRLINFQNHSPKPNGPVL----PPHPQQLRYPPNQN 511
QQQ QPP P P+ P + PP ++ N
Sbjct: 520 QQQVYAQKHQQLQQMRMQQPPAPVPTTTTTTQQHPRQAAPQMLQQQPPRLISVQTMQRGN 579
Query: 512 IPRQAIKPNPLQMAFLA------------QQAIKQWQISSGQGTPS--------TTNSTS 551
+ A + + +++A A Q ++ Q + P + ++T+
Sbjct: 580 MNCGAFQAHQMRLAQNAARIPGIPRHSGPQYSMMQPHLQRQHSNPGHAGPFPVVSVHNTT 639
Query: 552 STPSSPTITSAAGYDGKAFGSPM---IDLSSPVGGSYNLPSLPDI-----DCSSTIMLDN 603
P+SPT + A + + SP I+L V NLPSLPDI + + + LDN
Sbjct: 640 INPTSPTTATMANAN-RGPTSPSVTAIELIPSVTNPENLPSLPDIPPIQLEDAGSSSLDN 698
Query: 604 IVRKDTNIDHGQPRPPSNRTVQSPNSSVPSPGLAGPVTMTSVHPPIRSPSASSVGSRGSS 663
++ + + H P+P S SP S SPG +G +++ H P+R PS SS GSRGS
Sbjct: 699 LLSRYISGSHLPPQPTSTMN-PSPGPSALSPGSSG---LSNSHTPVRPPSTSSTGSRGSC 754
Query: 664 GSSSKPAGADSTHKVPVVMLEPIRIKQENSGPPENYDFPVVIVKQESDEESR-------- 715
GSS + A S + +++KQE E F VKQE E+ R
Sbjct: 755 GSSGRTAEKTSLS----FKSDQVKVKQEPGTEDEICSFSGG-VKQEKTEDGRRSACMLSS 809
Query: 716 PQNANYPRSILTSLLLNSSQSS-TSEETVLRSDAPDSTGDQPGLHQDNSSNGKSEWLDPS 774
P+++ P + T+L L S + S E ++ + D + NGKS
Sbjct: 810 PESSLTP-PLSTNLHLESELDALASLENHVKIEPADMNESCKQSGLSSLVNGKSPIRSLM 868
Query: 775 QKSPLHVGE-TRKEDDPNEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWIC 833
+S G+ K+DDPNEDWCAVCQNGG+LLCCEKCPKVFHL+CHVPTL +FPSG+WIC
Sbjct: 869 HRSARIGGDGNNKDDDPNEDWCAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFPSGDWIC 928
Query: 834 TFCRDLSKPEVEYDCDAPSHNSEKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDP 893
TFCRD+ KPEVEYDCD H+ + K +GL +P+D+RKCERLLL+LYCHE+S+ FQ+P
Sbjct: 929 TFCRDIGKPEVEYDCDNLQHSKKGKTAQGL---SPVDQRKCERLLLYLYCHELSIEFQEP 985
Query: 894 VPLTVPDYYKIIKNPMDLSTIKKRLQEDYSM-YSKPEDFVADFRLIFQNCAEFNE----- 947
VP ++P+YYKIIK PMDLST+KK+LQ+ +S Y P+DFVAD RLIF+NC FNE
Sbjct: 986 VPASIPNYYKIIKKPMDLSTVKKKLQKKHSQHYQIPDDFVADVRLIFKNCERFNEMMKVV 1045
Query: 948 ------------PDSEVANAGIKLENYFEELLKNLYPEKRF-PKPEFRNESEDNKFSDDS 994
DSEVA AG + YFE+ L +Y ++ F P PEF E +D + ++DS
Sbjct: 1046 QVYADTQEINLKADSEVAQAGKAVALYFEDKLTEIYSDRTFAPLPEFEQEEDDGEVTEDS 1105
Query: 995 DDDFVQPRKKRLKSIE 1010
D+DF+QPR+KRLKS E
Sbjct: 1106 DEDFIQPRRKRLKSDE 1121
>gi|5032179 tripartite motif-containing 28 protein [Homo sapiens]
Length = 835
Score = 310 bits (793), Expect = 6e-84
Identities = 165/433 (38%), Positives = 253/433 (58%), Gaps = 40/433 (9%)
Query: 8 AVAAAAAASAAASGGP------------SAAPSGENEAESRQGPDSERGGEAARLNLLDT 55
A AA+AAA++AASG P S APS A + S GG A L LL+
Sbjct: 5 AAAASAAAASAASGSPGPGEGSAGGEKRSTAPSAAASASASAAASSPAGGGAEALELLEH 64
Query: 56 CAVCHQNIQ-SRAPKLLPCLHSFCQRCLPAPQRYLMLPAPMLGSAETPPPVPAPGSPVSG 114
C VC + ++ R P+LLPCLHS C CL P PA + SG
Sbjct: 65 CGVCRERLRPEREPRLLPCLHSACSACLG-------------------PAAPAAANS-SG 104
Query: 115 SSPFATQVGVIRCPVCSQECAERHIIDNFFVKDTTEVPSSTVEKSNQVCTSCEDNAEANG 174
A V+ CPVC Q+C + I++N+F++D+ ++ + +NQ CTSCEDNA A
Sbjct: 105 DGGAAGDGTVVDCPVCKQQCFSKDIVENYFMRDSGSKAATDAQDANQCCTSCEDNAPATS 164
Query: 175 FCVECVEWLCKTCIRAHQRVKFTKDHTVRQKEEVSPEAVGVTSQRPVFCPFHKKEQLKLY 234
+CVEC E LC+TC+ AHQRVK+TKDHTVR + A +R V+C HK E L L+
Sbjct: 165 YCVECSEPLCETCVEAHQRVKYTKDHTVRS----TGPAKSRDGERTVYCNVHKHEPLVLF 220
Query: 235 CETCDKLTCRDCQLLEHKEHRYQFIEEAFQNQKVIIDTLITKLMEKTKYIKFTGNQIQNR 294
CE+CD LTCRDCQL HK+H+YQF+E+A +NQ+ ++ +L+ +L +K ++ + ++++
Sbjct: 221 CESCDTLTCRDCQLNAHKDHQYQFLEDAVRNQRKLLASLVKRLGDKHATLQKSTKEVRSS 280
Query: 295 IIEVNQNQKQVEQDIKVAIFTLMVEINKKGKALLHQLESLAKDHRMKLMQQQQEVAGLSK 354
I +V+ QK+V+ D+K+AI +M E+NK+G+ L++ + + + + +L +Q + + K
Sbjct: 281 IRQVSDVQKRVQVDVKMAILQIMKELNKRGRVLVNDAQKVTEGQQERLERQHWTMTKIQK 340
Query: 355 QLEHVMHFSKWAVSSGSSTALLYSKRLITYRLRHLLRARCDASPV-TNNTIQFHCDPSFW 413
EH++ F+ WA+ S ++TALL SK+LI ++L L+ D PV + ++F D + W
Sbjct: 341 HQEHILRFASWALESDNNTALLLSKKLIYFQLHRALKMIVD--PVEPHGEMKFQWDLNAW 398
Query: 414 AQNIINLGSLVIE 426
++ G +V E
Sbjct: 399 TKSAEAFGKIVAE 411
Score = 104 bits (259), Expect = 5e-22
Identities = 64/194 (32%), Positives = 98/194 (50%), Gaps = 16/194 (8%)
Query: 789 DPNEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDC 848
D + C VCQ G+L+ C +C FHL CH+P L + P EW C+ C L P+++ +
Sbjct: 622 DDSATICRVCQKPGDLVMCNQCEFCFHLDCHLPALQDVPGEEWSCSLCHVL--PDLKEE- 678
Query: 849 DAPSHNSEKKKTEGLVKLTPIDKRKCERLLLFLYCHE-----MSLAFQDPVPLTVPDYYK 903
D T + KL+P ++RKCER+LL L+CHE LA L P
Sbjct: 679 DGSLSLDGADSTGVVAKLSPANQRKCERVLLALFCHEPCRPLHQLATDSTFSLDQPG--- 735
Query: 904 IIKNPMDLSTIKKRLQEDYS-MYSKPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLENY 962
+DL+ I+ RLQE S YS P++F D +F+ + E ++V + I L+ +
Sbjct: 736 ---GTLDLTLIRARLQEKLSPPYSSPQEFAQDVGRMFKQFNKLTEDKADVQSI-IGLQRF 791
Query: 963 FEELLKNLYPEKRF 976
FE + + + +F
Sbjct: 792 FETRMNEAFGDTKF 805
>gi|209977097 tripartite motif-containing 66 [Homo sapiens]
Length = 1216
Score = 246 bits (627), Expect = 1e-64
Identities = 155/415 (37%), Positives = 223/415 (53%), Gaps = 48/415 (11%)
Query: 628 NSSVPSPGLAGPVTMTSVHPPIRSPSASSVGSRGSSGSSSKPAGA----DSTHKVPVVML 683
N SV P LA V+ ++ ++P +G+ +K + +S HK+P V L
Sbjct: 805 NLSVKKPPLAPVVSTSTALQQYQNPKECENFEQGALELDAKENQSIRAFNSEHKIPYVRL 864
Query: 684 EPIRIKQENSGPPENYDFPVVIVKQESDEESRPQNANYPRSILTSLLLNSSQSSTSEETV 743
E ++I +SG + PV +K PQ + S L L++ S+S
Sbjct: 865 ERLKICAASSG-----EMPVFKLK--------PQKNDQDGSFL--LIIECGTESSSMSIK 909
Query: 744 LRSDAPDSTGDQPGLHQDN----SSNGKS----EWLDPSQKSPLHVGETRKEDDP----N 791
+ D PGL S G+ E P + + K+ P N
Sbjct: 910 VSQDRLSEATQAPGLEGRKVTVTSLAGQRPPEVEGTSPEEHRLIPRTPGAKKGPPAPIEN 969
Query: 792 EDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDAP 851
ED+CAVC NGGELLCC++CPKVFHLSCHVP L +FP GEW+CT CR L++PE+EYDC+
Sbjct: 970 EDFCAVCLNGGELLCCDRCPKVFHLSCHVPALLSFPGGEWVCTLCRSLTQPEMEYDCENA 1029
Query: 852 SHNSEKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTVPDYYKIIKNPMDL 911
+N + L+ D++KCE+L+L L C+ +SL F +PV YY+IIK PMDL
Sbjct: 1030 CYNQPGMRAS--PGLSMYDQKKCEKLVLSLCCNNLSLPFHEPVSPLARHYYQIIKRPMDL 1087
Query: 912 STIKKRLQ-EDYSMYSKPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLENYFEELLKNL 970
S I+++LQ +D + Y+ PE+ V+D RL+F NCA+FN PDSEVA AG LE +FE LK +
Sbjct: 1088 SIIRRKLQKKDPAHYTTPEEVVSDVRLMFWNCAKFNYPDSEVAEAGRCLEVFFEGWLKEI 1147
Query: 971 YPEKRFPKPEFRNESEDNKFSDDSD-------------DDFVQPRKKRLKSIEER 1012
YPEKRF +P + +S+ + S +S + +QP+++R ER
Sbjct: 1148 YPEKRFAQPR-QEDSDSEEVSSESGCSTPQGFPWPPYMQEGIQPKRRRRHMENER 1201
Score = 211 bits (537), Expect = 3e-54
Identities = 161/619 (26%), Positives = 272/619 (43%), Gaps = 48/619 (7%)
Query: 163 CTSCEDNAEANGFCVECVEWLCKTCIRAHQRVKFTKDHTVRQKEEVSPEAVGVTSQRPVF 222
C+ C++ A+ C C WLC +C H+ + ++ SP G ++
Sbjct: 5 CSECKEKRAAHILCTYCNRWLCSSCTEEHRHSPVPGGPFFPRAQKGSPGVNGGPGDFTLY 64
Query: 223 CPFHKKEQLKLYCETCDKLTCRDCQLLEHKEHRYQFIEEAFQNQKVIIDTLITKLMEKTK 282
CP H +E LKL+CETCD LTC C ++EHKEHR + +EE QNQ+++++ + T++ K
Sbjct: 65 CPLHTQEVLKLFCETCDMLTCHSCLVVEHKEHRCRHVEEVLQNQRMLLEGVTTQVAHKKS 124
Query: 283 YIKFTGNQIQNRIIEVNQNQKQVEQDIKVAIFTLMVEINKKGKALLHQLESLAKDHRMKL 342
++ + QI++RI EV ++VE IK+A LM E+NK+ L+ +LE + + + KL
Sbjct: 125 SLQTSAKQIEDRIFEVKHQHRKVENQIKMAKMVLMNELNKQANGLIEELEGITNERKRKL 184
Query: 343 MQQQQEVAGLSKQLEHVMHFSKWAVSSGSSTALLYSKRLITYRLRHLLRARCDASPVTNN 402
QQ Q + L++Q EHV +F WAV S +S L+SK LI ++++ LL C+ P +
Sbjct: 185 EQQLQSIMVLNRQFEHVQNFINWAVCSKTSVPFLFSKELIVFQMQRLLETSCNTDPGSPW 244
Query: 403 TIQFHCDPSFWAQNIINLGSLVIEDKESQPQMPKQNPVVEQNSQPPSGLSSNQLSKFPTQ 462
+I+F +P+FW + + +LG + E QM + + Q S + S Q
Sbjct: 245 SIRFTWEPNFWTKQLASLGCITTEG----GQMSRADAPAYGGLQGSSPFYQSHQSPVAQQ 300
Query: 463 ISLAQLRLQHMQQQQPPPRLINFQ---NH----SPKPNGPVLPP--HPQQLRYPPNQNIP 513
+L+ H + P + + +H SP G V PP HP P + +P
Sbjct: 301 EALS-----HPSHKFQSPAVCSSSVCCSHCSPVSPSLKGQVPPPSIHPAHSFRQPPEMVP 355
Query: 514 RQAIKPNPLQMAFLAQQAIKQWQISSGQGTPSTTNSTSSTPSSPTITSAAGYDGKAFGSP 573
+Q LQ + L ++ +++ P T S + G+ S
Sbjct: 356 QQL---GSLQCSALLP---REKELACSPHPPKLLQPWLETQPPVEQESTSQRLGQQLTSQ 409
Query: 574 MIDLSSPVGGSYNLPSLPDIDCSSTIMLDNIVRKDTNIDHGQPRPPSNRTVQSPNSSVPS 633
+ + P + P + S I + + + H Q +P P P
Sbjct: 410 PVCIVPPQDVQQGAHAQPTLQTPS-IQVQFGHHQKLKLSHFQQQPQQQLPPPPPPLPHPP 468
Query: 634 PGLAGPVTMTSVHPPIRSPSASSVGSRGSSGSSSKPAGADSTHKVPVVMLEPIRIKQENS 693
P L P HPP+ PS S+ S P G + + +M +++
Sbjct: 469 PPLPPPPQQP--HPPL-PPSQHLASSQHES-----PPGPACSQNMD-IMHHKFELEEMQK 519
Query: 694 GPPENYDFPVVIVKQES----DEESRPQNANYPRSILTSLLLNSS---QSSTSEETVLRS 746
D +++ Q+ + PQ+ + ++ QS + EET+ +
Sbjct: 520 ------DLELLLQAQQPSLQLSQTKSPQHLQQTIVGQINYIVRQPAPVQSQSQEETLQAT 573
Query: 747 DAPD-STGDQPGLHQDNSS 764
D P S G +P L D ++
Sbjct: 574 DEPPASQGSKPALPLDKNT 592
>gi|224548923 tripartite motif-containing 45 isoform 2 [Homo
sapiens]
Length = 562
Score = 128 bits (322), Expect = 2e-29
Identities = 96/350 (27%), Positives = 157/350 (44%), Gaps = 21/350 (6%)
Query: 66 RAPKLLPCLHSFCQRCLPAPQRYLMLPAPMLGSAETPPPVPAPGSPVSGSSP--FATQVG 123
+AP+LLPCLH+ C CL + + ++ G ++T + GS P +Q+G
Sbjct: 37 KAPRLLPCLHTVCTTCLEQLEPFSVVDIRG-GDSDTS----SEGSIFQELKPRSLQSQIG 91
Query: 124 VIRCPVCSQEC------AERHIIDNFFVKDTTEVPSSTVEKSNQVCTSCEDNAEANGFCV 177
++ CPVC + + ID+ V D + S E VC C D E C
Sbjct: 92 IL-CPVCDAQVDLPMGGVKALTIDHLAVNDVM-LESLRGEGQGLVCDLCNDR-EVEKRCQ 148
Query: 178 ECVEWLCKTCIRAHQRVKFTKDHT-VRQKEEVSPEAVGVTSQRPVFCPFHKKEQLKLYCE 236
C LC C +AH+R K T HT V K+ +G +P+ CP H E+L+L+CE
Sbjct: 149 TCKANLCHFCCQAHRRQKKTTYHTMVDLKDLKGYSRIG----KPILCPVHPAEELRLFCE 204
Query: 237 TCDKLTCRDCQLLEHKEHRYQFIEEAFQNQKVIIDTLITKLMEKTKYIKFTGNQIQNRII 296
CD+ C+DC + EH+EH F + L+ + ++ QI
Sbjct: 205 FCDRPVCQDCVVGEHREHPCDFTSNVIHKHGDSVWELLKGTQPHVEALEEALAQIHIINS 264
Query: 297 EVNQNQKQVEQDIKVAIFTLMVEINKKGKALLHQLESLAKDHRMKLMQQQQEVAGLSKQL 356
+ + + V D++ + I + LL QLE + L Q+ ++ L +
Sbjct: 265 ALQKRVEAVAADVRTFSEGYIKAIEEHRDKLLKQLEDIRAQKENSLQLQKAQLEQLLADM 324
Query: 357 EHVMHFSKWAVSSGSSTALLYSKRLITYRLRHLLRARCDASPVTNNTIQF 406
+ F++ ++SGS +L +KR++ RLR L + + P N+ I+F
Sbjct: 325 RTGVEFTEHLLTSGSDLEILITKRVVVERLRKLNKVQYSTRPGVNDKIRF 374
>gi|224548921 tripartite motif-containing 45 isoform 1 [Homo
sapiens]
Length = 580
Score = 128 bits (322), Expect = 2e-29
Identities = 96/350 (27%), Positives = 157/350 (44%), Gaps = 21/350 (6%)
Query: 66 RAPKLLPCLHSFCQRCLPAPQRYLMLPAPMLGSAETPPPVPAPGSPVSGSSP--FATQVG 123
+AP+LLPCLH+ C CL + + ++ G ++T + GS P +Q+G
Sbjct: 37 KAPRLLPCLHTVCTTCLEQLEPFSVVDIRG-GDSDTS----SEGSIFQELKPRSLQSQIG 91
Query: 124 VIRCPVCSQEC------AERHIIDNFFVKDTTEVPSSTVEKSNQVCTSCEDNAEANGFCV 177
++ CPVC + + ID+ V D + S E VC C D E C
Sbjct: 92 IL-CPVCDAQVDLPMGGVKALTIDHLAVNDVM-LESLRGEGQGLVCDLCNDR-EVEKRCQ 148
Query: 178 ECVEWLCKTCIRAHQRVKFTKDHT-VRQKEEVSPEAVGVTSQRPVFCPFHKKEQLKLYCE 236
C LC C +AH+R K T HT V K+ +G +P+ CP H E+L+L+CE
Sbjct: 149 TCKANLCHFCCQAHRRQKKTTYHTMVDLKDLKGYSRIG----KPILCPVHPAEELRLFCE 204
Query: 237 TCDKLTCRDCQLLEHKEHRYQFIEEAFQNQKVIIDTLITKLMEKTKYIKFTGNQIQNRII 296
CD+ C+DC + EH+EH F + L+ + ++ QI
Sbjct: 205 FCDRPVCQDCVVGEHREHPCDFTSNVIHKHGDSVWELLKGTQPHVEALEEALAQIHIINS 264
Query: 297 EVNQNQKQVEQDIKVAIFTLMVEINKKGKALLHQLESLAKDHRMKLMQQQQEVAGLSKQL 356
+ + + V D++ + I + LL QLE + L Q+ ++ L +
Sbjct: 265 ALQKRVEAVAADVRTFSEGYIKAIEEHRDKLLKQLEDIRAQKENSLQLQKAQLEQLLADM 324
Query: 357 EHVMHFSKWAVSSGSSTALLYSKRLITYRLRHLLRARCDASPVTNNTIQF 406
+ F++ ++SGS +L +KR++ RLR L + + P N+ I+F
Sbjct: 325 RTGVEFTEHLLTSGSDLEILITKRVVVERLRKLNKVQYSTRPGVNDKIRF 374
>gi|84993742 tripartite motif-containing 71 [Homo sapiens]
Length = 868
Score = 108 bits (269), Expect = 3e-23
Identities = 66/274 (24%), Positives = 125/274 (45%), Gaps = 19/274 (6%)
Query: 152 PSSTVEKSNQVCTSCEDNAEANGFCVECVEWLCKTCIRAHQRVKFTKDHTVR-------- 203
PS+ + + C+SC++ A+ C++C E LC C+RAHQRV+ TKDH +
Sbjct: 188 PSALLLRRPHGCSSCDEGNAASSRCLDCQEHLCDNCVRAHQRVRLTKDHYIERGPPGPGA 247
Query: 204 ----QKEEVSPEAVG-------VTSQRPVFCPFHKKEQLKLYCETCDKLTCRDCQLLEHK 252
Q+ + P G V +R FC H E L LYC+TC CR+C + H
Sbjct: 248 AAAAQQLGLGPPFPGPPFSILSVFPERLGFCQHHDDEVLHLYCDTCSVPICRECTMGRHG 307
Query: 253 EHRYQFIEEAFQNQKVIIDTLITKLMEKTKYIKFTGNQIQNRIIEVNQNQKQVEQDIKVA 312
H + +++EA Q+ + + L+ + + I+ + Q Q +V K V+ ++K
Sbjct: 308 GHSFIYLQEALQDSRALTIQLLADAQQGRQAIQLSIEQAQTVAEQVEMKAKVVQSEVKAV 367
Query: 313 IFTLMVEINKKGKALLHQLESLAKDHRMKLMQQQQEVAGLSKQLEHVMHFSKWAVSSGSS 372
+ ++ LL ++E + + L Q +++ +LE + + + G +
Sbjct: 368 TARHKKALEERECELLWKVEKIRQVKAKSLYLQVEKLRQNLNKLESTISAVQQVLEEGRA 427
Query: 373 TALLYSKRLITYRLRHLLRARCDASPVTNNTIQF 406
+L ++ + +++ L R P ++ + F
Sbjct: 428 LDILLARDRMLAQVQELKTVRSLLQPQEDDRVMF 461
Score = 37.4 bits (85), Expect = 0.072
Identities = 34/117 (29%), Positives = 45/117 (38%), Gaps = 42/117 (35%)
Query: 17 AAASGGPSAAPSGENEAESRQGPDSERGGEAARLNLLDTCAVCHQNIQSRAPKLLPCLHS 76
A S SA+ S + S G G A RL++L PCLH+
Sbjct: 23 APLSSNSSASSSSSQTSTSSGGGGGGPGAAARRLHVL------------------PCLHA 64
Query: 77 FCQRCLPAPQRYLMLPAPMLGSAETPPPVPAPGSPVSGSSPFATQVGVIRCPVCSQE 133
FC+ CL A + LPA G+A G P+ +RCPVC Q+
Sbjct: 65 FCRPCLEAHR----LPAAGGGAA---------GEPLK-----------LRCPVCDQK 97
Score = 32.3 bits (72), Expect = 2.3
Identities = 32/121 (26%), Positives = 46/121 (38%), Gaps = 30/121 (24%)
Query: 14 AASAAASGGPSAAPSGENEAESRQGPDSERGGEAARLNLLDTCAVCHQNIQSRAPKLLPC 73
A S +A GGP+A+PS A L C+ C + + + + L C
Sbjct: 175 APSRSAPGGPAASPS------------------ALLLRRPHGCSSCDEG-NAASSRCLDC 215
Query: 74 LHSFCQRCLPAPQR-------YLMLPAPMLGSAETPPPV----PAPGSPVSGSSPFATQV 122
C C+ A QR Y+ P G+A + P PG P S S F ++
Sbjct: 216 QEHLCDNCVRAHQRVRLTKDHYIERGPPGPGAAAAAQQLGLGPPFPGPPFSILSVFPERL 275
Query: 123 G 123
G
Sbjct: 276 G 276
>gi|190343006 SP110 nuclear body protein isoform c [Homo sapiens]
Length = 713
Score = 104 bits (259), Expect = 5e-22
Identities = 67/180 (37%), Positives = 94/180 (52%), Gaps = 14/180 (7%)
Query: 791 NEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDA 850
N D C VC GG+LLCC CP+VFH CH+P + W CTFCR + + C
Sbjct: 533 NSDECEVCCQGGQLLCCGTCPRVFHEDCHIPPV-EAKRMLWSCTFCR-MKRSSGSQQCHH 590
Query: 851 PSHNSEKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTVPDYYKIIKNPMD 910
S E+ ++ P D+ KCE LLL YCH S +F +P + DY + + M
Sbjct: 591 VSKTLER-------QMQPQDQLKCEFLLLKAYCHPQS-SFFTGIPFNIRDYGEPFQEAMW 642
Query: 911 LSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLENYFEELLKNL 970
L +K+RL + MY+ FV D RL+F+N F + S+ G+ LE FE+ LK++
Sbjct: 643 LDLVKERLITE--MYTVAW-FVRDMRLMFRNHKTFYKA-SDFGQVGLDLEAEFEKDLKDV 698
>gi|134133279 SP140 nuclear body protein-like [Homo sapiens]
Length = 580
Score = 102 bits (255), Expect = 1e-21
Identities = 71/188 (37%), Positives = 94/188 (50%), Gaps = 25/188 (13%)
Query: 791 NEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDA 850
N D C VC++GGEL CC+ C +VFH CH+P + + W C FCR P + C
Sbjct: 402 NLDECEVCRDGGELFCCDTCSRVFHEDCHIPPVES-EKTPWNCIFCRMKESPGSQQCC-- 458
Query: 851 PSHNSEKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTVPDYYKI------ 904
E + E ++ P ++ KCE LLL +YC S F +P YY I
Sbjct: 459 ----QESEVLER--QMCPEEQLKCEFLLLKVYCCSESSFF-----AKIPYYYYIREACQG 507
Query: 905 IKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQN-CAEFNEPDSEVANAGIKLENYF 963
+K PM L IKKRL E Y + E FV D RLIFQN A + D G++LE F
Sbjct: 508 LKEPMWLDKIKKRLNE--HGYPQVEGFVQDMRLIFQNHRASYKYKD--FGQMGLRLEAEF 563
Query: 964 EELLKNLY 971
E+ K ++
Sbjct: 564 EKDFKEVF 571
>gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo
sapiens]
Length = 1905
Score = 101 bits (252), Expect = 3e-21
Identities = 72/234 (30%), Positives = 105/234 (44%), Gaps = 47/234 (20%)
Query: 787 EDDPNEDWCAVCQNGGE---LLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFC-RDLSKP 842
E N+ C VC+ G LL C+ C + H+ CH P + P G+W CT C +
Sbjct: 1671 EKSVNKVTCLVCRKGDNDEFLLLCDGCDRGCHIYCHRPKMEAVPEGDWFCTVCLAQQVEG 1730
Query: 843 EVEYDCDAPSHNSEKKK------TEG-------LVK---------------LTPIDKRK- 873
E P ++K +EG L++ L+P +R+
Sbjct: 1731 EFTQKPGFPKRGQKRKSGYSLNFSEGDGRRRRVLLRGRESPAAGPRYSEEGLSPSKRRRL 1790
Query: 874 -----------CERLLLFLYCHEMSLAFQDPV-PLTVPDYYKIIKNPMDLSTIKKRLQED 921
CE +L+ + H+ + F +PV P V Y +IIKNPMD ST+++RL
Sbjct: 1791 SMRNHHSDLTFCEIILMEMESHDAAWPFLEPVNPRLVSGYRRIIKNPMDFSTMRERLLR- 1849
Query: 922 YSMYSKPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLENYFEELLKNLYPEKR 975
Y+ E+F AD L+F NC FNE DSEV AG + +FE + Y K+
Sbjct: 1850 -GGYTSSEEFAADALLVFDNCQTFNEDDSEVGKAGHIMRRFFESRWEEFYQGKQ 1902
>gi|217330601 SP140 nuclear body protein isoform 1 [Homo sapiens]
Length = 867
Score = 101 bits (251), Expect = 4e-21
Identities = 71/188 (37%), Positives = 92/188 (48%), Gaps = 25/188 (13%)
Query: 791 NEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDA 850
N D C VC++GGEL CC+ C +VFH CH+P + W C FCR P + C
Sbjct: 689 NLDECEVCRDGGELFCCDTCSRVFHEDCHIPPV-EAERTPWNCIFCRMKESPGSQQCC-- 745
Query: 851 PSHNSEKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTVPDYYKI------ 904
E + E ++ P ++ KCE LLL +YC S F +P YY I
Sbjct: 746 ----QESEVLER--QMCPEEQLKCEFLLLKVYCCSESSFF-----AKIPYYYYIREACQG 794
Query: 905 IKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQN-CAEFNEPDSEVANAGIKLENYF 963
+K PM L IKKRL E Y + E FV D RLIFQN A + D G +LE F
Sbjct: 795 LKEPMWLDKIKKRLNE--HGYPQVEGFVQDMRLIFQNHRASYKYKD--FGQMGFRLEAEF 850
Query: 964 EELLKNLY 971
E+ K ++
Sbjct: 851 EKNFKEVF 858
>gi|122939208 nuclear antigen Sp100 isoform 1 [Homo sapiens]
Length = 885
Score = 99.8 bits (247), Expect = 1e-20
Identities = 62/182 (34%), Positives = 94/182 (51%), Gaps = 11/182 (6%)
Query: 791 NEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDA 850
N + C VC G L CC+ CP+ FH CH+P++ W C FCR + E
Sbjct: 701 NSNICEVCNKWGRLFCCDTCPRSFHEHCHIPSV-EANKNPWSCIFCRIKTIQE-----RC 754
Query: 851 PSHNSEKKKTEGLVK-LTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTVPDYYKIIKNPM 909
P S +++E L++ + P ++ KCE LLL +YC S F P + + + PM
Sbjct: 755 PESQSGHQESEVLMRQMLPEEQLKCEFLLLKVYCDSKSCFFASE-PYYNREGSQGPQKPM 813
Query: 910 DLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLENYFEELLKN 969
L+ +K L E MY++ E FV D RLIF N EF D + GI++++ FE+ +N
Sbjct: 814 WLNKVKTSLNE--QMYTRVEGFVQDMRLIFHNHKEFYRED-KFTRLGIQVQDIFEKNFRN 870
Query: 970 LY 971
++
Sbjct: 871 IF 872
>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
sapiens]
Length = 2168
Score = 97.1 bits (240), Expect = 8e-20
Identities = 69/232 (29%), Positives = 94/232 (40%), Gaps = 65/232 (28%)
Query: 794 WCAVCQNGGE---LLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFC-------------- 836
+C +C+ G LL C+ C K H CH P +T P G+W C C
Sbjct: 1933 YCQICRKGDNEELLLLCDGCDKGCHTYCHRPKITTIPDGDWFCPACIAKASGQTLKIKKL 1992
Query: 837 --------------------------------------RDLSKPEVEYDCDAPSHNSEKK 858
+DL K ++E + S N K+
Sbjct: 1993 HVKGKKTNESKKGKKVTLTGDTEDEDSASTSSSLKRGNKDLKKRKME---ENTSINLSKQ 2049
Query: 859 KTEGLVKLTPIDKRK----CERLLLFLYCHEMSLAFQDPVPLT-VPDYYKIIKNPMDLST 913
++ VK D K C +L + HE + F PV L VP Y K+IK PMD ST
Sbjct: 2050 ESFTSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVIKKPMDFST 2109
Query: 914 IKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLENYFEE 965
I+++L Y E F D RL+F NC FNE DS++ AG + YFE+
Sbjct: 2110 IREKLSS--GQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHNMRKYFEK 2159
>gi|34335264 zinc finger, MYND-type containing 8 isoform c [Homo
sapiens]
Length = 1135
Score = 90.9 bits (224), Expect = 6e-18
Identities = 69/230 (30%), Positives = 108/230 (46%), Gaps = 26/230 (11%)
Query: 734 SQSSTSEETVLRSDAPDSTGDQPGLHQDNSSNGKSEWLDPSQKSPLHVGETRKEDDPNED 793
S T+++ S S G P QD S++ + +K L +++D N+
Sbjct: 32 SAERTAQKRKFPSPPHSSNGHSP---QDTSTSP----IKKKKKPGLLNSNNKEQDGRNDF 84
Query: 794 WCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDAPSH 853
+C VC G++LCCE CP+V+H C LT+ P G+W C C ++ E + S
Sbjct: 85 YCWVCHREGQVLCCELCPRVYHAKC--LRLTSEPEGDWFCPECEKITVAEC---IETQSK 139
Query: 854 NSEKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTV-PDYYKIIKNPMDLS 912
E L L +K ++ + AFQ PVPL PDY + I +PMDL
Sbjct: 140 AMTMLTIEQLSYLLKFAIQKMKQ--------PGTDAFQKPVPLEQHPDYAEYIFHPMDLC 191
Query: 913 TIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPD---SEVANAGIKL 959
T++K ++ MY E F+AD + I NC +N + +++A IK+
Sbjct: 192 TLEKNAKK--KMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKI 239
>gi|34335262 zinc finger, MYND-type containing 8 isoform a [Homo
sapiens]
Length = 1188
Score = 89.0 bits (219), Expect = 2e-17
Identities = 71/236 (30%), Positives = 109/236 (46%), Gaps = 26/236 (11%)
Query: 732 NSSQSSTSEETVLRSDAPDSTGDQPGLHQDNSSNGKSEWLDPS--QKSPLHVG--ETRKE 787
+SS + ++T S +P +PGL N+ P K PL + +
Sbjct: 47 HSSNGHSPQDT---STSPIKKKKKPGLLNSNNKEQSELRHGPFYYMKQPLTTDPVDVVPQ 103
Query: 788 DDPNEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYD 847
D N+ +C VC G++LCCE CP+V+H C LT+ P G+W C C ++ E
Sbjct: 104 DGRNDFYCWVCHREGQVLCCELCPRVYHAKC--LRLTSEPEGDWFCPECEKITVAEC--- 158
Query: 848 CDAPSHNSEKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTV-PDYYKIIK 906
+ S E L L +K ++ + AFQ PVPL PDY + I
Sbjct: 159 IETQSKAMTMLTIEQLSYLLKFAIQKMKQ--------PGTDAFQKPVPLEQHPDYAEYIF 210
Query: 907 NPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPD---SEVANAGIKL 959
+PMDL T++K ++ MY E F+AD + I NC +N + +++A IK+
Sbjct: 211 HPMDLCTLEKNAKK--KMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKI 264
>gi|34335266 zinc finger, MYND-type containing 8 isoform b [Homo
sapiens]
Length = 1160
Score = 89.0 bits (219), Expect = 2e-17
Identities = 71/236 (30%), Positives = 109/236 (46%), Gaps = 26/236 (11%)
Query: 732 NSSQSSTSEETVLRSDAPDSTGDQPGLHQDNSSNGKSEWLDPS--QKSPLHVG--ETRKE 787
+SS + ++T S +P +PGL N+ P K PL + +
Sbjct: 47 HSSNGHSPQDT---STSPIKKKKKPGLLNSNNKEQSELRHGPFYYMKQPLTTDPVDVVPQ 103
Query: 788 DDPNEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYD 847
D N+ +C VC G++LCCE CP+V+H C LT+ P G+W C C ++ E
Sbjct: 104 DGRNDFYCWVCHREGQVLCCELCPRVYHAKC--LRLTSEPEGDWFCPECEKITVAEC--- 158
Query: 848 CDAPSHNSEKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTV-PDYYKIIK 906
+ S E L L +K ++ + AFQ PVPL PDY + I
Sbjct: 159 IETQSKAMTMLTIEQLSYLLKFAIQKMKQ--------PGTDAFQKPVPLEQHPDYAEYIF 210
Query: 907 NPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPD---SEVANAGIKL 959
+PMDL T++K ++ MY E F+AD + I NC +N + +++A IK+
Sbjct: 211 HPMDLCTLEKNAKK--KMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKI 264
>gi|67089160 promyelocytic leukemia protein isoform 11 [Homo
sapiens]
Length = 781
Score = 85.5 bits (210), Expect = 2e-16
Identities = 135/641 (21%), Positives = 239/641 (37%), Gaps = 98/641 (15%)
Query: 27 PSGENEAESRQGPDSERGGEAARLNLLD----TCAVCHQNIQSRAPKLLPCLHSFCQRCL 82
P E +E RQ S E A + + C C +++ PKLLPCLH+ C CL
Sbjct: 24 PPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQCQA--EAKCPKLLPCLHTLCSGCL 81
Query: 83 PAPQRYLMLPAPMLGSAETPPPVPAPGSPVSGSSPFATQVGVIRCPVCSQEC---AERHI 139
A SG ++CP+C A+
Sbjct: 82 EA----------------------------SG----------MQCPICQAPWPLGADTPA 103
Query: 140 IDNFFVKDTTEVPS--STVEKSNQVCTSCEDNAEANGFCVECVEWLCKTCIRAHQRVKFT 197
+DN F + S + + VCT C+++A+ +C EC + LC C AHQ +
Sbjct: 104 LDNVFFESLQRRLSVYRQIVDAQAVCTRCKESADF--WCFECEQLLCAKCFEAHQ---WF 158
Query: 198 KDHTVRQKEEVSPEAV-----GVTSQRPVFC--PFHKKEQL-KLYCETCDKLTCRDCQLL 249
H R E+ ++V G +FC P H+ L +YC C K C C LL
Sbjct: 159 LKHEARPLAELRNQSVREFLDGTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALL 218
Query: 250 E--HKEHRYQFIEEAFQNQKVIIDTLITKLMEKTKYIKFTGNQIQNRIIEVNQNQKQVEQ 307
+ H E + E Q Q+ +D + L E+ Q+ + ++ + + + E+
Sbjct: 219 DSSHSELKCDISAEIQQRQEE-LDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEE 277
Query: 308 DIKVAIFTLMVEINKKGKALLHQLESLAKDHRMKLMQQQQEVAGLSKQLEHVMHFSKWAV 367
I+ + ++ + + + LL +++ + + +E+A +L+ V+ +
Sbjct: 278 LIRERVRQVVAHVRAQERELLEAVDA-------RYQRDYEEMASRLGRLDAVLQRIRTGS 330
Query: 368 SSGSSTALLYSKRLITYRLRHLLRARCDASPVTNNTIQFHCDPSFWAQ---NIINLGSLV 424
+ S + + L +A C ++Q + + + +L S +
Sbjct: 331 ALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCI 390
Query: 425 IEDKESQPQMPKQNPVVEQNSQPPSGLS---SNQLSKFPTQISLAQLRLQHMQQQQPPPR 481
+ K++ K +P + P + SN + + S Q + ++ + +
Sbjct: 391 TQGKDAAVS-KKASPEAASTPRDPIDVDLDVSNTTTAQKRKCSQTQCPRKVIKMESEEGK 449
Query: 482 LINFQNHSPKPNGP-----VLPPHPQQLRYPPNQNIPRQAIKPNPLQMAFLAQQAIKQWQ 536
SP+ P V PPH P + I + PN +A A +A ++
Sbjct: 450 EARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLPNSNHVASGAGEAEERVV 509
Query: 537 ISSGQGTPSTTNS------TSSTPSSPTITSAAGYDGKAFGSPMIDL------SSPVGGS 584
+ S NS T+ SSP +S A + A SP+ L SS G+
Sbjct: 510 VISSSEDSDAENSCMEPMETAEPQSSPAHSSPA-HSSPAHSSPVQSLLRAQGASSLPCGT 568
Query: 585 YNLPSLPDIDCSSTIMLDNIVRKDTNIDHGQPRPPSNRTVQ 625
Y+ P+ P + + DH Q RP +R ++
Sbjct: 569 YHPPAWPPHQPAEQAATPDAEPHSEPPDH-QERPAVHRGIR 608
>gi|119943102 CREB binding protein isoform b [Homo sapiens]
Length = 2404
Score = 84.7 bits (208), Expect = 4e-16
Identities = 141/565 (24%), Positives = 201/565 (35%), Gaps = 87/565 (15%)
Query: 430 SQPQMPK---QNPVVEQNS--QPPSG---LSSNQLSKFPTQISLAQLRLQHMQQQQPP-- 479
+QP +P Q PV+ Q +PP+G L N++ S + L ++Q Q P
Sbjct: 643 NQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMG 702
Query: 480 PRLINFQNHSPKPNG----PVLPPHPQQLRYPPNQNIPRQAIKPNPLQMAFLAQQAIKQW 535
PR + NHS + N P + P ++ PPN A N + A Q + Q
Sbjct: 703 PRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNM---MGAHTNNMMAQAPAQSQFLPQN 759
Query: 536 QISSGQGTPSTTNSTSSTPSSPTITSAAGYDGKAFGSPMIDLSSPVGGSYNLPSLPDIDC 595
Q S G S P + T S G A +P+ L P + C
Sbjct: 760 QFPSSSGAMSVG---MGQPPAQTGVSQGQVPGAALPNPLNMLG---------PQASQLPC 807
Query: 596 SSTIMLDNIVRKDTNIDHGQPRPPSNRTVQSPNSSVPSPGLAGPVTMTSVHPPIRSPSAS 655
H P P S PG+ P P S S
Sbjct: 808 PPVTQSPL---------HPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQP---STPVS 855
Query: 656 SVGSRGSSGSSSKPAGADSTHKVPVVMLEPIRIKQENSGPPENYDFPVVIVKQESDEESR 715
S G + S P+ A T P V + Q P P V Q S ++
Sbjct: 856 SSGQTPTPTPGSVPS-ATQTQSTPTV--QAAAQAQVTPQPQTPVQPPSVATPQSSQQQPT 912
Query: 716 PQNANYPRSILTSLLLN------SSQSSTSEETVLRSDAPDSTGDQPGLHQDNSSNGKSE 769
P +A P + L+ + + S S ET + PD P L + +
Sbjct: 913 PVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDV----PVLEMKTETQAEDT 968
Query: 770 WLDPSQKSPLHVGETRKEDDPNEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSG 829
DP + GE R E ED Q E E+ + + P +
Sbjct: 969 EPDPGESK----GEPRSEM-MEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEV------ 1017
Query: 830 EWICTFCRDLSKPEVEYDCDAPSHNSEKKKTEGLVKLTPIDKRKCERLLLF-----LYCH 884
K EV+ + ++ S+ + + T I K + R L LY
Sbjct: 1018 -----------KVEVKEEEESSSNGTASQSTSPSQPRKKIFKPEELRQALMPTLEALYRQ 1066
Query: 885 EM-SLAFQDPVP---LTVPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQ 940
+ SL F+ PV L +PDY+ I+KNPMDLSTIK++L D Y +P +V D L+F
Sbjct: 1067 DPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKL--DTGQYQEPWQYVDDVWLMFN 1124
Query: 941 NCAEFNEPDSEVANAGIKLENYFEE 965
N +N S V KL FE+
Sbjct: 1125 NAWLYNRKTSRVYKFCSKLAEVFEQ 1149
>gi|119943104 CREB binding protein isoform a [Homo sapiens]
Length = 2442
Score = 84.7 bits (208), Expect = 4e-16
Identities = 141/565 (24%), Positives = 201/565 (35%), Gaps = 87/565 (15%)
Query: 430 SQPQMPK---QNPVVEQNS--QPPSG---LSSNQLSKFPTQISLAQLRLQHMQQQQPP-- 479
+QP +P Q PV+ Q +PP+G L N++ S + L ++Q Q P
Sbjct: 681 NQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMG 740
Query: 480 PRLINFQNHSPKPNG----PVLPPHPQQLRYPPNQNIPRQAIKPNPLQMAFLAQQAIKQW 535
PR + NHS + N P + P ++ PPN A N + A Q + Q
Sbjct: 741 PRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNM---MGAHTNNMMAQAPAQSQFLPQN 797
Query: 536 QISSGQGTPSTTNSTSSTPSSPTITSAAGYDGKAFGSPMIDLSSPVGGSYNLPSLPDIDC 595
Q S G S P + T S G A +P+ L P + C
Sbjct: 798 QFPSSSGAMSVG---MGQPPAQTGVSQGQVPGAALPNPLNMLG---------PQASQLPC 845
Query: 596 SSTIMLDNIVRKDTNIDHGQPRPPSNRTVQSPNSSVPSPGLAGPVTMTSVHPPIRSPSAS 655
H P P S PG+ P P S S
Sbjct: 846 PPVTQSPL---------HPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQP---STPVS 893
Query: 656 SVGSRGSSGSSSKPAGADSTHKVPVVMLEPIRIKQENSGPPENYDFPVVIVKQESDEESR 715
S G + S P+ A T P V + Q P P V Q S ++
Sbjct: 894 SSGQTPTPTPGSVPS-ATQTQSTPTV--QAAAQAQVTPQPQTPVQPPSVATPQSSQQQPT 950
Query: 716 PQNANYPRSILTSLLLN------SSQSSTSEETVLRSDAPDSTGDQPGLHQDNSSNGKSE 769
P +A P + L+ + + S S ET + PD P L + +
Sbjct: 951 PVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDV----PVLEMKTETQAEDT 1006
Query: 770 WLDPSQKSPLHVGETRKEDDPNEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSG 829
DP + GE R E ED Q E E+ + + P +
Sbjct: 1007 EPDPGESK----GEPRSEM-MEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEV------ 1055
Query: 830 EWICTFCRDLSKPEVEYDCDAPSHNSEKKKTEGLVKLTPIDKRKCERLLLF-----LYCH 884
K EV+ + ++ S+ + + T I K + R L LY
Sbjct: 1056 -----------KVEVKEEEESSSNGTASQSTSPSQPRKKIFKPEELRQALMPTLEALYRQ 1104
Query: 885 EM-SLAFQDPVP---LTVPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQ 940
+ SL F+ PV L +PDY+ I+KNPMDLSTIK++L D Y +P +V D L+F
Sbjct: 1105 DPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKL--DTGQYQEPWQYVDDVWLMFN 1162
Query: 941 NCAEFNEPDSEVANAGIKLENYFEE 965
N +N S V KL FE+
Sbjct: 1163 NAWLYNRKTSRVYKFCSKLAEVFEQ 1187
>gi|32454739 tripartite motif-containing 3 [Homo sapiens]
Length = 744
Score = 84.7 bits (208), Expect = 4e-16
Identities = 79/377 (20%), Positives = 146/377 (38%), Gaps = 90/377 (23%)
Query: 56 CAVCHQNIQSRAPKLLPCLHSFCQRCLPAPQRYLMLPAPMLGSAETPPPVPAPGSPVSGS 115
C++C Q PK+LPCLH+FC+RCL Q Y+ PA L
Sbjct: 22 CSICLDRYQ--CPKVLPCLHTFCERCL---QNYI--PAQSL------------------- 55
Query: 116 SPFATQVGVIRCPVCSQ-----ECAERHIIDNFFVKDTTEVPSSTVEKSNQVCTSCEDNA 170
+ CPVC Q E + +NFF+ SS +E Q D
Sbjct: 56 --------TLSCPVCRQTSILPEQGVSALQNNFFI-------SSLMEAMQQAPDGAHDPE 100
Query: 171 EANGFCVECVEWLCKTCIRAHQRVKFTKDHTVRQKEEVSPEAVGVTSQRPVFCPFHKKEQ 230
+ P + V + RP+ CP H+ +
Sbjct: 101 D--------------------------------------PHPLSVVAGRPLSCPNHEGKT 122
Query: 231 LKLYCETCDKLTCRDCQLLEHKEHRYQFIEEAFQNQKVIIDTLITKLMEKTKYIKFTGNQ 290
++ YCE C+ C +C+ EH+EH + + + K + + + + +
Sbjct: 123 MEFYCEACETAMCGECRAGEHREHGTVLLRDVVEQHKAALQRQLEAVRGRLPQLSAAIAL 182
Query: 291 IQNRIIEVNQNQKQVEQDIKVAIFTLMVEINKKGKALLHQLESLAKDHRMKLMQQQQEVA 350
+ ++ + + + I A L + ++ +AL+ LE++ + K++Q Q +
Sbjct: 183 VGGISQQLQERKAEALAQISAAFEDLEQALQQRKQALVSDLETIC-GAKQKVLQSQLDT- 240
Query: 351 GLSKQLEHV---MHFSKWAVSSGSSTALLYSKRLITYRLRHLLRARCDASPVTNNTIQFH 407
L + EH+ F++ A+ GS+ +L ++ + RL L P N ++
Sbjct: 241 -LRQGQEHIGSSCSFAEQALRLGSAPEVLLVRKHMRERLAALAAQAFPERPHENAQLELV 299
Query: 408 CDPSFWAQNIINLGSLV 424
+ ++++NLG+L+
Sbjct: 300 LEVDGLRRSVLNLGALL 316
>gi|32454737 tripartite motif-containing 3 [Homo sapiens]
Length = 744
Score = 84.7 bits (208), Expect = 4e-16
Identities = 79/377 (20%), Positives = 146/377 (38%), Gaps = 90/377 (23%)
Query: 56 CAVCHQNIQSRAPKLLPCLHSFCQRCLPAPQRYLMLPAPMLGSAETPPPVPAPGSPVSGS 115
C++C Q PK+LPCLH+FC+RCL Q Y+ PA L
Sbjct: 22 CSICLDRYQ--CPKVLPCLHTFCERCL---QNYI--PAQSL------------------- 55
Query: 116 SPFATQVGVIRCPVCSQ-----ECAERHIIDNFFVKDTTEVPSSTVEKSNQVCTSCEDNA 170
+ CPVC Q E + +NFF+ SS +E Q D
Sbjct: 56 --------TLSCPVCRQTSILPEQGVSALQNNFFI-------SSLMEAMQQAPDGAHDPE 100
Query: 171 EANGFCVECVEWLCKTCIRAHQRVKFTKDHTVRQKEEVSPEAVGVTSQRPVFCPFHKKEQ 230
+ P + V + RP+ CP H+ +
Sbjct: 101 D--------------------------------------PHPLSVVAGRPLSCPNHEGKT 122
Query: 231 LKLYCETCDKLTCRDCQLLEHKEHRYQFIEEAFQNQKVIIDTLITKLMEKTKYIKFTGNQ 290
++ YCE C+ C +C+ EH+EH + + + K + + + + +
Sbjct: 123 MEFYCEACETAMCGECRAGEHREHGTVLLRDVVEQHKAALQRQLEAVRGRLPQLSAAIAL 182
Query: 291 IQNRIIEVNQNQKQVEQDIKVAIFTLMVEINKKGKALLHQLESLAKDHRMKLMQQQQEVA 350
+ ++ + + + I A L + ++ +AL+ LE++ + K++Q Q +
Sbjct: 183 VGGISQQLQERKAEALAQISAAFEDLEQALQQRKQALVSDLETIC-GAKQKVLQSQLDT- 240
Query: 351 GLSKQLEHV---MHFSKWAVSSGSSTALLYSKRLITYRLRHLLRARCDASPVTNNTIQFH 407
L + EH+ F++ A+ GS+ +L ++ + RL L P N ++
Sbjct: 241 -LRQGQEHIGSSCSFAEQALRLGSAPEVLLVRKHMRERLAALAAQAFPERPHENAQLELV 299
Query: 408 CDPSFWAQNIINLGSLV 424
+ ++++NLG+L+
Sbjct: 300 LEVDGLRRSVLNLGALL 316
>gi|194248081 tripartite motif-containing 2 isoform 2 [Homo sapiens]
Length = 744
Score = 84.0 bits (206), Expect = 7e-16
Identities = 81/379 (21%), Positives = 149/379 (39%), Gaps = 92/379 (24%)
Query: 56 CAVCHQNIQSRAPKLLPCLHSFCQRCLPAPQRYLMLPAPMLGSAETPPPVPAPGSPVSGS 115
C++C + ++ PK+LPCLH+FC+RCL Q Y+ PA L
Sbjct: 23 CSICLERYKN--PKVLPCLHTFCERCL---QNYI--PAHSL------------------- 56
Query: 116 SPFATQVGVIRCPVCSQ-----ECAERHIIDNFFVKDTTEV----PSSTVEKSNQVCTSC 166
+ CPVC Q E + +NFF+ + +V P S E+S+ +
Sbjct: 57 --------TLSCPVCRQTSILPEKGVAALQNNFFITNLMDVLQRTPGSNAEESSIL---- 104
Query: 167 EDNAEANGFCVECVEWLCKTCIRAHQRVKFTKDHTVRQKEEVSPEAVGVTSQRPVFCPFH 226
E V+ A G +P+ CP H
Sbjct: 105 ---------------------------------------ETVTAVAAG----KPLSCPNH 121
Query: 227 KKEQLKLYCETCDKLTCRDCQLLEHKEHRYQFIEEAFQNQKVIIDTLITKLMEKTKYIKF 286
++ YC++C+ CR+C EH EH +++ + K + + + ++ I
Sbjct: 122 DGNVMEFYCQSCETAMCRECTEGEHAEHPTVPLKDVVEQHKASLQVQLDAVNKRLPEIDS 181
Query: 287 TGNQIQNRIIEVNQNQKQVEQDIKVAIFTLMVEINKKGKALLHQLE-SLAKDHRMKLMQQ 345
I I ++ + + DI L +N + LL +LE + H++ L Q
Sbjct: 182 ALQFISEIIHQLTNQKASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGLKHKV-LQSQ 240
Query: 346 QQEVAGLSKQLEHVMHFSKWAVSSGSSTALLYSKRLITYRLRHLLRARCDASPVTNNTIQ 405
+ + ++ +F+ A++ G+ T +L K+ ++ +L L P N+ +
Sbjct: 241 LDTLLQGQESIKSCSNFTAQALNHGTETEVLLVKKQMSEKLNELADQDFPLHPRENDQLD 300
Query: 406 FHCDPSFWAQNIINLGSLV 424
F + ++I NLG+++
Sbjct: 301 FIVETEGLKKSIHNLGTIL 319
>gi|194248079 tripartite motif-containing 2 isoform 1 [Homo sapiens]
Length = 771
Score = 84.0 bits (206), Expect = 7e-16
Identities = 81/379 (21%), Positives = 149/379 (39%), Gaps = 92/379 (24%)
Query: 56 CAVCHQNIQSRAPKLLPCLHSFCQRCLPAPQRYLMLPAPMLGSAETPPPVPAPGSPVSGS 115
C++C + ++ PK+LPCLH+FC+RCL Q Y+ PA L
Sbjct: 50 CSICLERYKN--PKVLPCLHTFCERCL---QNYI--PAHSL------------------- 83
Query: 116 SPFATQVGVIRCPVCSQ-----ECAERHIIDNFFVKDTTEV----PSSTVEKSNQVCTSC 166
+ CPVC Q E + +NFF+ + +V P S E+S+ +
Sbjct: 84 --------TLSCPVCRQTSILPEKGVAALQNNFFITNLMDVLQRTPGSNAEESSIL---- 131
Query: 167 EDNAEANGFCVECVEWLCKTCIRAHQRVKFTKDHTVRQKEEVSPEAVGVTSQRPVFCPFH 226
E V+ A G +P+ CP H
Sbjct: 132 ---------------------------------------ETVTAVAAG----KPLSCPNH 148
Query: 227 KKEQLKLYCETCDKLTCRDCQLLEHKEHRYQFIEEAFQNQKVIIDTLITKLMEKTKYIKF 286
++ YC++C+ CR+C EH EH +++ + K + + + ++ I
Sbjct: 149 DGNVMEFYCQSCETAMCRECTEGEHAEHPTVPLKDVVEQHKASLQVQLDAVNKRLPEIDS 208
Query: 287 TGNQIQNRIIEVNQNQKQVEQDIKVAIFTLMVEINKKGKALLHQLE-SLAKDHRMKLMQQ 345
I I ++ + + DI L +N + LL +LE + H++ L Q
Sbjct: 209 ALQFISEIIHQLTNQKASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGLKHKV-LQSQ 267
Query: 346 QQEVAGLSKQLEHVMHFSKWAVSSGSSTALLYSKRLITYRLRHLLRARCDASPVTNNTIQ 405
+ + ++ +F+ A++ G+ T +L K+ ++ +L L P N+ +
Sbjct: 268 LDTLLQGQESIKSCSNFTAQALNHGTETEVLLVKKQMSEKLNELADQDFPLHPRENDQLD 327
Query: 406 FHCDPSFWAQNIINLGSLV 424
F + ++I NLG+++
Sbjct: 328 FIVETEGLKKSIHNLGTIL 346
>gi|38788260 bromodomain PHD finger transcription factor isoform 2
[Homo sapiens]
Length = 2903
Score = 82.4 bits (202), Expect = 2e-15
Identities = 66/222 (29%), Positives = 98/222 (44%), Gaps = 29/222 (13%)
Query: 756 PGLHQDNSSNGKSEWLDPSQKSPLH--VGETRKEDDPNEDWCAVCQNGGE----LLCCEK 809
P L + + E D S KS + T KE + +C+ + + C++
Sbjct: 2685 PTLPAASQKRKREEEKDSSSKSKKKKMISTTSKETKKDTKLYCICKTPYDESKFYIGCDR 2744
Query: 810 CPKVFHLSCHVPTLTNFPS--GEWICTFCRDLSKPEVEYDCDAPSHNSEKKKTEGLVKLT 867
C +H C V L + E++C C+ S + L LT
Sbjct: 2745 CQNWYHGRC-VGILQSEAELIDEYVCPQCQ-----------------STEDAMTVLTPLT 2786
Query: 868 PIDKRKCERLLLFLYCHEMSLAFQDPV-PLTVPDYYKIIKNPMDLSTIKKRLQEDYSMYS 926
D +R+L L H+M+ F +PV P PDYY +IK PMDL+T+++R+Q Y Y
Sbjct: 2787 EKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRY--YE 2844
Query: 927 KPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLENYFEELLK 968
K +FVAD IF NC +N DS LE++F + LK
Sbjct: 2845 KLTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLK 2886
Score = 60.1 bits (144), Expect = 1e-08
Identities = 34/90 (37%), Positives = 42/90 (46%), Gaps = 6/90 (6%)
Query: 792 EDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDAP 851
+D C VC G+LLCCE C V+HL C P L P EW C C P V DC A
Sbjct: 390 DDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVT-DCVA- 447
Query: 852 SHNSEKKKTEGLVKLTPIDKRKCERLLLFL 881
E +K + ++ PI + R FL
Sbjct: 448 ----EIQKNKPYIRHEPIGYDRSRRKYWFL 473
>gi|38788274 bromodomain PHD finger transcription factor isoform 1
[Homo sapiens]
Length = 2920
Score = 82.4 bits (202), Expect = 2e-15
Identities = 66/222 (29%), Positives = 98/222 (44%), Gaps = 29/222 (13%)
Query: 756 PGLHQDNSSNGKSEWLDPSQKSPLH--VGETRKEDDPNEDWCAVCQNGGE----LLCCEK 809
P L + + E D S KS + T KE + +C+ + + C++
Sbjct: 2702 PTLPAASQKRKREEEKDSSSKSKKKKMISTTSKETKKDTKLYCICKTPYDESKFYIGCDR 2761
Query: 810 CPKVFHLSCHVPTLTNFPS--GEWICTFCRDLSKPEVEYDCDAPSHNSEKKKTEGLVKLT 867
C +H C V L + E++C C+ S + L LT
Sbjct: 2762 CQNWYHGRC-VGILQSEAELIDEYVCPQCQ-----------------STEDAMTVLTPLT 2803
Query: 868 PIDKRKCERLLLFLYCHEMSLAFQDPV-PLTVPDYYKIIKNPMDLSTIKKRLQEDYSMYS 926
D +R+L L H+M+ F +PV P PDYY +IK PMDL+T+++R+Q Y Y
Sbjct: 2804 EKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRY--YE 2861
Query: 927 KPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLENYFEELLK 968
K +FVAD IF NC +N DS LE++F + LK
Sbjct: 2862 KLTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLK 2903
Score = 60.1 bits (144), Expect = 1e-08
Identities = 34/90 (37%), Positives = 42/90 (46%), Gaps = 6/90 (6%)
Query: 792 EDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDAP 851
+D C VC G+LLCCE C V+HL C P L P EW C C P V DC A
Sbjct: 390 DDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVT-DCVA- 447
Query: 852 SHNSEKKKTEGLVKLTPIDKRKCERLLLFL 881
E +K + ++ PI + R FL
Sbjct: 448 ----EIQKNKPYIRHEPIGYDRSRRKYWFL 473
>gi|30794216 tripartite motif-containing 56 [Homo sapiens]
Length = 755
Score = 81.6 bits (200), Expect = 3e-15
Identities = 84/392 (21%), Positives = 147/392 (37%), Gaps = 50/392 (12%)
Query: 56 CAVCHQNIQSRAPKLLPCLHSFCQRCLPAPQRYLMLPAPMLGSAETPPPVPAPGSPVSGS 115
C +C + Q RAPK LPCLH++CQ CL + + E VP P G
Sbjct: 21 CKICLE--QLRAPKTLPCLHTYCQDCLAQ-----LADGGRVRCPECRETVPVPPE---GV 70
Query: 116 SPFATQVGVIRCPVCSQECAERHIIDNFFVKDTTEVPSST----VEKSNQVCTSC----- 166
+ F T NFFV ++ + + C C
Sbjct: 71 ASFKT---------------------NFFVNGLLDLVKARACGDLRAGKPACALCPLVGG 109
Query: 167 -EDNAEANGFCVECVEWLCKTCIRAHQRVKFTKDHTVRQKEEVSPEA----VGVTSQRPV 221
A C++C + LC+ C H+ + T HT R + V A ++
Sbjct: 110 TSTGGPATARCLDCADDLCQACADGHRCTRQT--HTHRVVDLVGYRAGWYDEEARERQAA 167
Query: 222 FCPFHKKEQLKLYCETCDKLTCRDCQLLEHKEHRYQFIEEAFQNQKVIIDTLITKLMEKT 281
CP H E L+ C+ C +L CR+C+L H +H + EA + ++ ++ L+ +
Sbjct: 168 QCPQHPGEALRFLCQPCSQLLCRECRLDPHLDHPCLPLAEAVRARRPGLEGLLAGVDNNL 227
Query: 282 KYIKFTGNQIQNRIIEVNQNQKQVEQDIKVAIFTLMVEINKKGKALLHQLESLAKDHRMK 341
++ + + + + +V ++ A ++ + + + +L QL + +
Sbjct: 228 VELEAARRVEKEALARLREQAARVGTQVEEAAEGVLRALLAQKQEVLGQLRAHVEAAEEA 287
Query: 342 LMQQQQEVAGLSKQLEHVMHFSKWAVSSGSSTALLYSKRLITYRLRHLLRARCDASPVTN 401
++ E+ G + F++ +S G +L + I RLR L P
Sbjct: 288 ARERLAELEGREQVARAAAAFARRVLSLGREAEILSLEGAIAQRLRQLQGCPWAPGPAPC 347
Query: 402 NTIQFHCDPSFWAQNIINLGSLVIEDKESQPQ 433
Q P + N L + +E QPQ
Sbjct: 348 LLPQLELHPGLLDK---NCHLLRLSFEEQQPQ 376
>gi|15451779 promyelocytic leukemia protein isoform 10 [Homo
sapiens]
Length = 585
Score = 79.3 bits (194), Expect = 2e-14
Identities = 114/555 (20%), Positives = 207/555 (37%), Gaps = 84/555 (15%)
Query: 27 PSGENEAESRQGPDSERGGEAARLNLLD----TCAVCHQNIQSRAPKLLPCLHSFCQRCL 82
P E +E RQ S E A + + C C +++ PKLLPCLH+ C CL
Sbjct: 24 PPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQCQA--EAKCPKLLPCLHTLCSGCL 81
Query: 83 PAPQRYLMLPAPMLGSAETPPPVPAPGSPVSGSSPFATQVGVIRCPVCSQEC---AERHI 139
A SG ++CP+C A+
Sbjct: 82 EA----------------------------SG----------MQCPICQAPWPLGADTPA 103
Query: 140 IDNFFVKDTTEVPS--STVEKSNQVCTSCEDNAEANGFCVECVEWLCKTCIRAHQRVKFT 197
+DN F + S + + VCT C+++A+ +C EC + LC C AHQ +
Sbjct: 104 LDNVFFESLQRRLSVYRQIVDAQAVCTRCKESADF--WCFECEQLLCAKCFEAHQ---WF 158
Query: 198 KDHTVRQKEEVSPEAV-----GVTSQRPVFC--PFHKKEQL-KLYCETCDKLTCRDCQLL 249
H R E+ ++V G +FC P H+ L +YC C K C C LL
Sbjct: 159 LKHEARPLAELRNQSVREFLDGTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALL 218
Query: 250 E--HKEHRYQFIEEAFQNQKVIIDTLITKLMEKTKYIKFTGNQIQNRIIEVNQNQKQVEQ 307
+ H E + E Q Q+ +D + L E+ Q+ + ++ + + + E+
Sbjct: 219 DSSHSELKCDISAEIQQRQEE-LDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEE 277
Query: 308 DIKVAIFTLMVEINKKGKALLHQLESLAKDHRMKLMQQQQEVAGLSKQLEHVMHFSKWAV 367
I+ + ++ + + + LL +++ + + +E+A +L+ V+ +
Sbjct: 278 LIRERVRQVVAHVRAQERELLEAVDA-------RYQRDYEEMASRLGRLDAVLQRIRTGS 330
Query: 368 SSGSSTALLYSKRLITYRLRHLLRARCDASPVTNNTIQFHCDPSFWAQ---NIINLGSLV 424
+ S + + L +A C ++Q + + + +L S +
Sbjct: 331 ALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCI 390
Query: 425 IEDKESQPQMPKQNPVVEQNSQPPSGLS---SNQLSKFPTQISLAQLRLQHMQQQQPPPR 481
+ K++ K +P + P + SN + + S Q + ++ + +
Sbjct: 391 TQGKDAAVS-KKASPEAASTPRDPIDVDLDVSNTTTAQKRKCSQTQCPRKVIKMESEEGK 449
Query: 482 LINFQNHSPKPNGP-----VLPPHPQQLRYPPNQNIPRQAIKPNPLQMAFLAQQAIKQWQ 536
SP+ P V PPH P + I + PN +A A +A ++
Sbjct: 450 EARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLPNSNHVASGAGEAEERVV 509
Query: 537 ISSGQGTPSTTNSTS 551
+ S NS+S
Sbjct: 510 VISSSEDSDAENSSS 524
Score = 33.5 bits (75), Expect = 1.0
Identities = 30/115 (26%), Positives = 46/115 (40%), Gaps = 16/115 (13%)
Query: 615 QPRPPSNRTVQSPNSSVPSPGLAGPVTMTSVHPPIRSPSASSVGSR-------------G 661
QPRP +++ V P+ P P PV + V P + AS G
Sbjct: 460 QPRPSTSKAVSPPHLDGP-PSPRSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSD 518
Query: 662 SSGSSSKPAGADSTHKVPVVMLEP--IRIKQENSGPPENYDFPVVIVKQESDEES 714
+ SSS+ S+ + + P +R+ EN P+ D P+V + D ES
Sbjct: 519 AENSSSRELDDSSSESSDLQLEGPSTLRVLDENLADPQAEDRPLVFFDLKIDNES 573
>gi|67089157 promyelocytic leukemia protein isoform 2 [Homo sapiens]
Length = 611
Score = 79.0 bits (193), Expect = 2e-14
Identities = 77/326 (23%), Positives = 129/326 (39%), Gaps = 65/326 (19%)
Query: 27 PSGENEAESRQGPDSERGGEAARLNLLD----TCAVCHQNIQSRAPKLLPCLHSFCQRCL 82
P E +E RQ S E A + + C C +++ PKLLPCLH+ C CL
Sbjct: 24 PPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQCQA--EAKCPKLLPCLHTLCSGCL 81
Query: 83 PAPQRYLMLPAPMLGSAETPPPVPAPGSPVSGSSPFATQVGVIRCPVCSQEC---AERHI 139
A SG ++CP+C A+
Sbjct: 82 EA----------------------------SG----------MQCPICQAPWPLGADTPA 103
Query: 140 IDNFFVKDTTEVPS--STVEKSNQVCTSCEDNAEANGFCVECVEWLCKTCIRAHQRVKFT 197
+DN F + S + + VCT C+++A+ +C EC + LC C AHQ +
Sbjct: 104 LDNVFFESLQRRLSVYRQIVDAQAVCTRCKESADF--WCFECEQLLCAKCFEAHQ---WF 158
Query: 198 KDHTVRQKEEVSPEAV-----GVTSQRPVFC--PFHKKEQL-KLYCETCDKLTCRDCQLL 249
H R E+ ++V G +FC P H+ L +YC C K C C LL
Sbjct: 159 LKHEARPLAELRNQSVREFLDGTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALL 218
Query: 250 E--HKEHRYQFIEEAFQNQKVIIDTLITKLMEKTKYIKFTGNQIQNRIIEVNQNQKQVEQ 307
+ H E + E Q Q+ +D + L E+ Q+ + ++ + + + E+
Sbjct: 219 DSSHSELKCDISAEIQQRQEE-LDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEE 277
Query: 308 DIKVAIFTLMVEINKKGKALLHQLES 333
I+ + ++ + + + LL +++
Sbjct: 278 LIRERVRQVVAHVRAQERELLEAVDA 303
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,467,082
Number of Sequences: 37866
Number of extensions: 2629801
Number of successful extensions: 17434
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 184
Number of HSP's successfully gapped in prelim test: 558
Number of HSP's that attempted gapping in prelim test: 14356
Number of HSP's gapped (non-prelim): 3094
length of query: 1016
length of database: 18,247,518
effective HSP length: 112
effective length of query: 904
effective length of database: 14,006,526
effective search space: 12661899504
effective search space used: 12661899504
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.