Search of human proteins with 46488932

Search of human proteins with 46488932

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|46488932 interferon-alpha receptor 1 precursor [Homo
sapiens]
         (557 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|46488932 interferon-alpha receptor 1 precursor [Homo sapiens]     1132   0.0  
gi|24430215 interleukin 10 receptor, beta precursor [Homo sapiens]     95   2e-19
gi|31083156 interleukin 20 receptor, alpha [Homo sapiens]              70   4e-12
gi|47419934 interferon gamma receptor 2 precursor [Homo sapiens]       57   6e-08
gi|40255073 interleukin 20 receptor beta precursor [Homo sapiens]      54   5e-07
gi|31317241 interleukin 22-binding protein isoform 2 [Homo sapiens]    54   5e-07
gi|31317239 interleukin 22 receptor, alpha 1 [Homo sapiens]            51   3e-06
gi|16418459 interleukin 22-binding protein isoform 1 [Homo sapiens]    50   5e-06
gi|4557880 interferon gamma receptor 1 precursor [Homo sapiens]        45   1e-04
gi|56676330 HP1-BP74 [Homo sapiens]                                    40   0.004
gi|25014103 interleukin 28 receptor, alpha isoform 1 [Homo sapiens]    38   0.021
gi|28416911 interleukin 28 receptor, alpha isoform 3 [Homo sapiens]    38   0.021
gi|28416909 interleukin 28 receptor, alpha isoform 2 [Homo sapiens]    38   0.021
gi|218505787 protocadherin 15 isoform CD2-1 precursor [Homo sapi...    37   0.062
gi|157311649 neogenin homolog 1 [Homo sapiens]                         35   0.14 
gi|110349719 titin isoform N2-A [Homo sapiens]                         35   0.24 
gi|110349717 titin isoform novex-2 [Homo sapiens]                      35   0.24 
gi|110349713 titin isoform novex-1 [Homo sapiens]                      35   0.24 
gi|110349715 titin isoform N2-B [Homo sapiens]                         35   0.24 
gi|222136575 interleukin 10 receptor, alpha precursor [Homo sapi...    34   0.31 
gi|4503641 coagulation factor III precursor [Homo sapiens]             34   0.31 
gi|4506309 protein tyrosine phosphatase, receptor type, D isofor...    34   0.40 
gi|18860890 protein tyrosine phosphatase, receptor type, D isofo...    34   0.40 
gi|18860892 protein tyrosine phosphatase, receptor type, D isofo...    34   0.40 
gi|118918395 fibronectin type III domain containing 3A isoform 1...    34   0.40 
gi|118918397 fibronectin type III domain containing 3A isoform 2...    34   0.40 
gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sap...    32   1.2  
gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sap...    32   1.2  
gi|21361639 DIPB protein [Homo sapiens]                                32   1.5  
gi|188497648 ubiquitin specific peptidase 37 [Homo sapiens]            32   1.5  

>gi|46488932 interferon-alpha receptor 1 precursor [Homo sapiens]
          Length = 557

 Score = 1132 bits (2928), Expect = 0.0
 Identities = 557/557 (100%), Positives = 557/557 (100%)

Query: 1   MMVVLLGATTLVLVAVAPWVLSAAAGGKNLKSPQKVEVDIIDDNFILRWNRSDESVGNVT 60
           MMVVLLGATTLVLVAVAPWVLSAAAGGKNLKSPQKVEVDIIDDNFILRWNRSDESVGNVT
Sbjct: 1   MMVVLLGATTLVLVAVAPWVLSAAAGGKNLKSPQKVEVDIIDDNFILRWNRSDESVGNVT 60

Query: 61  FSFDYQKTGMDNWIKLSGCQNITSTKCNFSSLKLNVYEEIKLRIRAEKENTSSWYEVDSF 120
           FSFDYQKTGMDNWIKLSGCQNITSTKCNFSSLKLNVYEEIKLRIRAEKENTSSWYEVDSF
Sbjct: 61  FSFDYQKTGMDNWIKLSGCQNITSTKCNFSSLKLNVYEEIKLRIRAEKENTSSWYEVDSF 120

Query: 121 TPFRKAQIGPPEVHLEAEDKAIVIHISPGTKDSVMWALDGLSFTYSLVIWKNSSGVEERI 180
           TPFRKAQIGPPEVHLEAEDKAIVIHISPGTKDSVMWALDGLSFTYSLVIWKNSSGVEERI
Sbjct: 121 TPFRKAQIGPPEVHLEAEDKAIVIHISPGTKDSVMWALDGLSFTYSLVIWKNSSGVEERI 180

Query: 181 ENIYSRHKIYKLSPETTYCLKVKAALLTSWKIGVYSPVHCIKTTVENELPPPENIEVSVQ 240
           ENIYSRHKIYKLSPETTYCLKVKAALLTSWKIGVYSPVHCIKTTVENELPPPENIEVSVQ
Sbjct: 181 ENIYSRHKIYKLSPETTYCLKVKAALLTSWKIGVYSPVHCIKTTVENELPPPENIEVSVQ 240

Query: 241 NQNYVLKWDYTYANMTFQVQWLHAFLKRNPGNHLYKWKQIPDCENVKTTQCVFPQNVFQK 300
           NQNYVLKWDYTYANMTFQVQWLHAFLKRNPGNHLYKWKQIPDCENVKTTQCVFPQNVFQK
Sbjct: 241 NQNYVLKWDYTYANMTFQVQWLHAFLKRNPGNHLYKWKQIPDCENVKTTQCVFPQNVFQK 300

Query: 301 GIYLLRVQASDGNNTSFWSEEIKFDTEIQAFLLPPVFNIRSLSDSFHIYIGAPKQSGNTP 360
           GIYLLRVQASDGNNTSFWSEEIKFDTEIQAFLLPPVFNIRSLSDSFHIYIGAPKQSGNTP
Sbjct: 301 GIYLLRVQASDGNNTSFWSEEIKFDTEIQAFLLPPVFNIRSLSDSFHIYIGAPKQSGNTP 360

Query: 361 VIQDYPLIYEIIFWENTSNAERKIIEKKTDVTVPNLKPLTVYCVKARAHTMDEKLNKSSV 420
           VIQDYPLIYEIIFWENTSNAERKIIEKKTDVTVPNLKPLTVYCVKARAHTMDEKLNKSSV
Sbjct: 361 VIQDYPLIYEIIFWENTSNAERKIIEKKTDVTVPNLKPLTVYCVKARAHTMDEKLNKSSV 420

Query: 421 FSDAVCEKTKPGNTSKIWLIVGICIALFALPFVIYAAKVFLRCINYVFFPSLKPSSSIDE 480
           FSDAVCEKTKPGNTSKIWLIVGICIALFALPFVIYAAKVFLRCINYVFFPSLKPSSSIDE
Sbjct: 421 FSDAVCEKTKPGNTSKIWLIVGICIALFALPFVIYAAKVFLRCINYVFFPSLKPSSSIDE 480

Query: 481 YFSEQPLKNLLLSTSEEQIEKCFIIENISTIATVEETNQTDEDHKKYSSQTSQDSGNYSN 540
           YFSEQPLKNLLLSTSEEQIEKCFIIENISTIATVEETNQTDEDHKKYSSQTSQDSGNYSN
Sbjct: 481 YFSEQPLKNLLLSTSEEQIEKCFIIENISTIATVEETNQTDEDHKKYSSQTSQDSGNYSN 540

Query: 541 EDESESKTSEELQQDFV 557
           EDESESKTSEELQQDFV
Sbjct: 541 EDESESKTSEELQQDFV 557


>gi|24430215 interleukin 10 receptor, beta precursor [Homo sapiens]
          Length = 325

 Score = 94.7 bits (234), Expect = 2e-19
 Identities = 79/322 (24%), Positives = 145/322 (45%), Gaps = 28/322 (8%)

Query: 209 SWKIGVYSPVHCIKTTVENELPPPENIEVSVQNQNYVLKWD---YTYANMTFQVQWLHAF 265
           +W +G +    C+  +    +PPPEN+ ++  N   +L+W+   +   N+TF  Q+L   
Sbjct: 2   AWSLGSWLG-GCLLVSALGMVPPPENVRMNSVNFKNILQWESPAFAKGNLTFTAQYLSYR 60

Query: 266 LKRNPGNHLYKWKQIPDCENVKTTQCVFPQNVFQKGIYLLRVQASDGNNTSFWSEEIKFD 325
           + ++             C N   T+C F  ++ + G + LRV+A   +  S W   I F 
Sbjct: 61  IFQDK------------CMNTTLTECDF-SSLSKYGDHTLRVRAEFADEHSDWVN-ITFC 106

Query: 326 TEIQAFLLPPVFNIRSLSDSFHIYIGAPKQSGN--TPVIQDY--PLIYEIIFWENTSNAE 381
                 + PP   +  L+DS H+   APK      T  +++      Y + +W+N ++ +
Sbjct: 107 PVDDTIIGPPGMQVEVLADSLHMRFLAPKIENEYETWTMKNVYNSWTYNVQYWKNGTDEK 166

Query: 382 RKIIEKKTDVTVPNLKPLTVYCVKARAHTMDEKLNKSSVFSDAVCEKTKPGNTSKIWLIV 441
            +I  +     + NL+P T YCV+ R    D   NK+  +S+ VCE+T    T   W++ 
Sbjct: 167 FQITPQYDFEVLRNLEPWTTYCVQVRGFLPDR--NKAGEWSEPVCEQTTHDETVPSWMVA 224

Query: 442 GICIA-LFALPFVIYAAKVFLRCINYVFFPSLKPSSSIDEYFSE---QPLKNLLLSTSEE 497
            I +A +F +   +      L C+      +  P +S+ ++  E    P  N LL  S  
Sbjct: 225 VILMASVFMVCLALLGCFALLWCVYKKTKYAFSPRNSLPQHLKEFLGHPHHNTLLFFSFP 284

Query: 498 QIEKCFIIENISTIATVEETNQ 519
             ++  + + +S IA   E+ +
Sbjct: 285 LSDENDVFDKLSVIAEDSESGK 306



 Score = 85.9 bits (211), Expect = 9e-17
 Identities = 67/224 (29%), Positives = 109/224 (48%), Gaps = 19/224 (8%)

Query: 19  WVLSAAAGGKNLKS-------PQKVEVDIIDDNFILRWNRSDESVGNVTFSFDYQKTGMD 71
           W L +  GG  L S       P+ V ++ ++   IL+W     + GN+TF+  Y    + 
Sbjct: 3   WSLGSWLGGCLLVSALGMVPPPENVRMNSVNFKNILQWESPAFAKGNLTFTAQY----LS 58

Query: 72  NWIKLSGCQNITSTKCNFSSLKLNVYEEIKLRIRAE-KENTSSWYEVDSFTPFRKAQIGP 130
             I    C N T T+C+FSSL  + Y +  LR+RAE  +  S W  + +F P     IGP
Sbjct: 59  YRIFQDKCMNTTLTECDFSSL--SKYGDHTLRVRAEFADEHSDWVNI-TFCPVDDTIIGP 115

Query: 131 PEVHLEA-EDKAIVIHISPGTKDSV-MWALDGL--SFTYSLVIWKNSSGVEERIENIYSR 186
           P + +E   D   +  ++P  ++    W +  +  S+TY++  WKN +  + +I   Y  
Sbjct: 116 PGMQVEVLADSLHMRFLAPKIENEYETWTMKNVYNSWTYNVQYWKNGTDEKFQITPQYDF 175

Query: 187 HKIYKLSPETTYCLKVKAALLTSWKIGVYSPVHCIKTTVENELP 230
             +  L P TTYC++V+  L    K G +S   C +TT +  +P
Sbjct: 176 EVLRNLEPWTTYCVQVRGFLPDRNKAGEWSEPVCEQTTHDETVP 219


>gi|31083156 interleukin 20 receptor, alpha [Homo sapiens]
          Length = 553

 Score = 70.5 bits (171), Expect = 4e-12
 Identities = 53/207 (25%), Positives = 91/207 (43%), Gaps = 17/207 (8%)

Query: 11  LVLVAVAPWVLSAAAGGKNLKSPQKVEVDIIDDNFILRWNRSDESVG-NVTFSFDYQKTG 69
           L+L+  APW  +       L  P  +    I+   +L+W   +   G  VT++  Y   G
Sbjct: 18  LLLLLAAPWGRAVPCVSGGLPKPANITFLSINMKNVLQWTPPEGLQGVKVTYTVQYFIYG 77

Query: 70  MDNWIKLSGCQNITSTKCNFSSLKLNVYEEIKLRIRAE-KENTSSWYEVDSFTPFRKAQI 128
              W+  S C+NI  T C+ S+   +   +   +++A      S W E   F PF + QI
Sbjct: 78  QKKWLNKSECRNINRTYCDLSAETSDYEHQYYAKVKAIWGTKCSKWAESGRFYPFLETQI 137

Query: 129 GPPEVHLEAEDKAIVIHISPGTK---------DSVMWALDGLSFTYSLVIWKNSSGVEER 179
           GPPEV L  ++K+I + ++   K          S+      L +  S++  K++    + 
Sbjct: 138 GPPEVALTTDEKSISVVLTAPEKWKRNPEDLPVSMQQIYSNLKYNVSVLNTKSNRTWSQC 197

Query: 180 IENIYSRHKIYK--LSPETTYCLKVKA 204
           + N    H +    L P T YC+ V++
Sbjct: 198 VTN----HTLVLTWLEPNTLYCVHVES 220



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 54/252 (21%), Positives = 95/252 (37%), Gaps = 32/252 (12%)

Query: 225 VENELPPPENIEVSVQNQNYVLKWD----YTYANMTFQVQWLHAFLKRNPGNHLYKWKQI 280
           V   LP P NI     N   VL+W          +T+ VQ+     K        KW   
Sbjct: 33  VSGGLPKPANITFLSINMKNVLQWTPPEGLQGVKVTYTVQYFIYGQK--------KWLNK 84

Query: 281 PDCENVKTTQC-VFPQNVFQKGIYLLRVQASDGNNTSFWSEEIKFDTEIQAFLLPPVFNI 339
            +C N+  T C +  +    +  Y  +V+A  G   S W+E  +F   ++  + PP   +
Sbjct: 85  SECRNINRTYCDLSAETSDYEHQYYAKVKAIWGTKCSKWAESGRFYPFLETQIGPPEVAL 144

Query: 340 RSLSDSFHIYIGAPKQSGNTPVIQDYP---------LIYEIIFWENTSNAERKIIEKKTD 390
            +   S  + + AP++    P  +D P         L Y +      SN           
Sbjct: 145 TTDEKSISVVLTAPEKWKRNP--EDLPVSMQQIYSNLKYNVSVLNTKSNRTWSQCVTNHT 202

Query: 391 VTVPNLKPLTVYCVKARAHTMDEKLNKSSVFSDAVCEKTKPGNTSK------IWLIVGIC 444
           + +  L+P T+YCV   +        + +  S+  C +T    +S+       W ++ + 
Sbjct: 203 LVLTWLEPNTLYCVHVESFVPGPP--RRAQPSEKQCARTLKDQSSEFKAKIIFWYVLPVS 260

Query: 445 IALFALPFVIYA 456
           I +F    + Y+
Sbjct: 261 ITVFLFSVMGYS 272


>gi|47419934 interferon gamma receptor 2 precursor [Homo sapiens]
          Length = 337

 Score = 56.6 bits (135), Expect = 6e-08
 Identities = 71/329 (21%), Positives = 136/329 (41%), Gaps = 31/329 (9%)

Query: 212 IGVYSPVHCIKTTVENELPPPENIEVSVQNQNYVLKWD-YTYANMT----FQVQWLHAFL 266
           +GV++          ++LP P++ ++ + N   VL W+    +N T    +QVQ+ +   
Sbjct: 13  LGVFAAAAAAPPDPLSQLPAPQHPKIRLYNAEQVLSWEPVALSNSTRPVVYQVQFKYTDS 72

Query: 267 KRNPGNHLYKWKQIPDCENVKTTQCVFPQNVFQKGIYL-----LRVQASDGNNTSFWSEE 321
           K    + +       +C  +  T+C F       G  +     LR++A  G   S W   
Sbjct: 73  KWFTADIMSIGV---NCTQITATECDFTAASPSAGFPMDFNVTLRLRAELGALHSAWVTM 129

Query: 322 IKFDTEIQAFLLPPV-FNIRSLSDSFHIYIGAPKQSGNTPVIQDYPLIYEIIFWENTSNA 380
             F       + PP    +     S  I   +P    +T         Y + +WE     
Sbjct: 130 PWFQHYRNVTVGPPENIEVTPGEGSLIIRFSSPFDIADTSTAF---FCYYVHYWEKGGIQ 186

Query: 381 ERKIIEKKTDVTVPNLKPLTVYCVKARAHTMDEKLNKSSVF-----SDAVCEKTKPGNTS 435
           + K   +   +++ NLKP  VYC++ +A  +    NKS++F     S+  C +T    ++
Sbjct: 187 QVKGPFRSNSISLDNLKPSRVYCLQVQAQLL---WNKSNIFRVGHLSNISCYETMADAST 243

Query: 436 KIWLIVGICIALFALPFVIYAAKVFL-----RCINYVFFPSLKPSSSIDEYFSEQPLKNL 490
           ++  ++ I +  F+L  V+  A  FL       I Y F         I+EY  + P + +
Sbjct: 244 ELQQVILISVGTFSLLSVLAGACFFLVLKYRGLIKYWFHTPPSIPLQIEEYLKD-PTQPI 302

Query: 491 LLSTSEEQIEKCFIIENISTIATVEETNQ 519
           L +  ++   K  + +++S I+  E+  +
Sbjct: 303 LEALDKDSSPKDDVWDSVSIISFPEKEQE 331



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 63/260 (24%), Positives = 110/260 (42%), Gaps = 28/260 (10%)

Query: 1   MMVVLLGATTLVLVAVAPWVLSAAAGGKNLKSPQKVEVDIIDDNFILRW------NRSDE 54
           M   LL +  L+L   A    +       L +PQ  ++ + +   +L W      N +  
Sbjct: 1   MRPTLLWSLLLLLGVFAAAAAAPPDPLSQLPAPQHPKIRLYNAEQVLSWEPVALSNSTRP 60

Query: 55  SVGNVTFSFDYQKTGMDNWIKLS-GCQNITSTKCNFS----SLKLNVYEEIKLRIRAEKE 109
            V  V F +   K    + + +   C  IT+T+C+F+    S    +   + LR+RAE  
Sbjct: 61  VVYQVQFKYTDSKWFTADIMSIGVNCTQITATECDFTAASPSAGFPMDFNVTLRLRAELG 120

Query: 110 NT-SSWYEVDSFTPFRKAQIGPPEVHLE---AEDKAIVIHISPGTKDSVMWALDGLSFTY 165
              S+W  +  F  +R   +GPPE ++E    E   I+   SP        A     F Y
Sbjct: 121 ALHSAWVTMPWFQHYRNVTVGPPE-NIEVTPGEGSLIIRFSSPFDIADTSTAF----FCY 175

Query: 166 SLVIWKNSSGVEERIENIYSRHKIY--KLSPETTYCLKVKAALLTS----WKIGVYSPVH 219
            +  W+   G  ++++  +  + I    L P   YCL+V+A LL +    +++G  S + 
Sbjct: 176 YVHYWE--KGGIQQVKGPFRSNSISLDNLKPSRVYCLQVQAQLLWNKSNIFRVGHLSNIS 233

Query: 220 CIKTTVENELPPPENIEVSV 239
           C +T  +      + I +SV
Sbjct: 234 CYETMADASTELQQVILISV 253


>gi|40255073 interleukin 20 receptor beta precursor [Homo sapiens]
          Length = 311

 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 68/306 (22%), Positives = 123/306 (40%), Gaps = 49/306 (16%)

Query: 215 YSPVHCIKTTVENELPPPENIEVSVQNQNYVLKW-------DYTYANMTFQVQWLHAFLK 267
           Y+ + C+ T     LP P+N+ V   N  ++L W       +  Y ++ +Q ++   +  
Sbjct: 21  YALIPCLLTDEVAILPAPQNLSVLSTNMKHLLMWSPVIAPGETVYYSVEYQGEYESLYT- 79

Query: 268 RNPGNHLYKWKQIPDCENVKTTQCVFPQNVFQKGIYLLRVQASDGNNTSFWSEEIKFDTE 327
               +H+  W     C   +  +C    ++     Y LRV+A+ G+ TS WS        
Sbjct: 80  ----SHI--WIPSSWCSLTEGPECDVTDDITATVPYNLRVRATLGSQTSAWSILKHPFNR 133

Query: 328 IQAFLLPPVFNIRSLSDSFHIYIGAPKQSGNTPVIQDYPLIYE--IIFWENTSNAERKII 385
               L  P   I    D FH+ I           ++D    +E  + +W     AE  + 
Sbjct: 134 NSTILTRPGMEI--TKDGFHLVI----------ELEDLGPQFEFLVAYWRREPGAEEHVK 181

Query: 386 EKKT---DVTVPNLKPLTVYCVKARAHTMDEKLNKSSVFSDAVCEKTKPGN---TSKIWL 439
             ++    V +  ++P   YCVKA+  T  + + + S FS   C + +         ++ 
Sbjct: 182 MVRSGGIPVHLETMEPGAAYCVKAQ--TFVKAIGRYSAFSQTECVEVQGEAIPLVLALFA 239

Query: 440 IVGICIALFALPFVIYAAKVFLR--CINYVFFP-SLKPSSSIDEYFSEQPLKNLLLSTSE 496
            VG  + L  +P  ++     L+  C   V  P +LK ++S        P K  L+S   
Sbjct: 240 FVGFMLILVVVPLFVWKMGRLLQYSCCPVVVLPDTLKITNS--------PQK--LISCRR 289

Query: 497 EQIEKC 502
           E+++ C
Sbjct: 290 EEVDAC 295



 Score = 36.6 bits (83), Expect = 0.062
 Identities = 41/208 (19%), Positives = 77/208 (37%), Gaps = 24/208 (11%)

Query: 30  LKSPQKVEVDIIDDNFILRWNRSDESVGNVTFSFDYQKT-----GMDNWIKLSGCQNITS 84
           L +PQ + V   +   +L W+        V +S +YQ           WI  S C     
Sbjct: 35  LPAPQNLSVLSTNMKHLLMWSPVIAPGETVYYSVEYQGEYESLYTSHIWIPSSWCSLTEG 94

Query: 85  TKCNFSSLKLNVYEEIKLRIRAEK-ENTSSWYEVDSFTPFRKAQ--IGPPEVHLEAEDKA 141
            +C+ +   +       LR+RA     TS+W  +    PF +    +  P + +  +   
Sbjct: 95  PECDVTD-DITATVPYNLRVRATLGSQTSAWSILKH--PFNRNSTILTRPGMEITKDGFH 151

Query: 142 IVIHISPGTKDSVMWALDGLSFTYSLVIWKNSSGVEERIENIYSRH---KIYKLSPETTY 198
           +VI +             G  F + +  W+   G EE ++ + S      +  + P   Y
Sbjct: 152 LVIELEDL----------GPQFEFLVAYWRREPGAEEHVKMVRSGGIPVHLETMEPGAAY 201

Query: 199 CLKVKAALLTSWKIGVYSPVHCIKTTVE 226
           C+K +  +    +   +S   C++   E
Sbjct: 202 CVKAQTFVKAIGRYSAFSQTECVEVQGE 229


>gi|31317241 interleukin 22-binding protein isoform 2 [Homo sapiens]
          Length = 231

 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 43/177 (24%), Positives = 77/177 (43%), Gaps = 9/177 (5%)

Query: 33  PQKVEVDIIDDNFILRWNRSDESVGNVTFSF-DYQKTGMDNWIKLSGCQNITSTKCNFSS 91
           PQ+V+    + + IL+W       GN +  F  Y+  G   W     C       C+ +S
Sbjct: 31  PQRVQFQSRNFHNILQWQPGRALTGNSSVYFVQYKIYGQRQWKNKEDCWGTQELSCDLTS 90

Query: 92  LKLNVYEEIKLRIRAEKENT-SSWYEVDSFTPFRKAQIGPPEVHL-EAEDKAIVIHISPG 149
              ++ E    R+RA    + S W     FTP+ + +I PP +++ +     +VI  +P 
Sbjct: 91  ETSDIQEPYYGRVRAASAGSYSEWSMTPRFTPWWETKIDPPVMNITQVNGSLLVILHAPN 150

Query: 150 -----TKDSVMWALDGLSFTYSLVIWKNSSGVEERI-ENIYSRHKIYKLSPETTYCL 200
                 K+  +   D     Y + I  NS   E+++ E  +   +I  L+P ++YC+
Sbjct: 151 LPYRYQKEKNVSIEDYYELLYRVFIINNSLEKEQKVYEGAHRAVEIEALTPHSSYCV 207



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 49/194 (25%), Positives = 77/194 (39%), Gaps = 26/194 (13%)

Query: 257 FQVQWLHAFLKRNPGNHL----------YK------WKQIPDCENVKTTQCVFPQNVFQ- 299
           FQ +  H  L+  PG  L          YK      WK   DC   +   C         
Sbjct: 36  FQSRNFHNILQWQPGRALTGNSSVYFVQYKIYGQRQWKNKEDCWGTQELSCDLTSETSDI 95

Query: 300 KGIYLLRVQASDGNNTSFWSEEIKFDTEIQAFLLPPVFNIRSLSDSFHIYIGAP------ 353
           +  Y  RV+A+   + S WS   +F    +  + PPV NI  ++ S  + + AP      
Sbjct: 96  QEPYYGRVRAASAGSYSEWSMTPRFTPWWETKIDPPVMNITQVNGSLLVILHAPNLPYRY 155

Query: 354 KQSGNTPVIQDYPLIYEIIFWENTSNAERKIIE-KKTDVTVPNLKPLTVYCVKARAHTMD 412
           ++  N  +   Y L+Y +    N+   E+K+ E     V +  L P + YCV A  +   
Sbjct: 156 QKEKNVSIEDYYELLYRVFIINNSLEKEQKVYEGAHRAVEIEALTPHSSYCVVAEIY--Q 213

Query: 413 EKLNKSSVFSDAVC 426
             L++ S  S+  C
Sbjct: 214 PMLDRRSQRSEERC 227


>gi|31317239 interleukin 22 receptor, alpha 1 [Homo sapiens]
          Length = 574

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 38/164 (23%), Positives = 71/164 (43%), Gaps = 15/164 (9%)

Query: 46  ILRWNRSDESVGNVTFSFDYQKTGMDNWIKLSGCQNITSTKCNFSSLKLNVYEEIKLRIR 105
           IL W+   E   +  +S +Y+  G  +W+   GCQ IT   CN +    N+ E    R+ 
Sbjct: 38  ILTWDSGPEGTPDTVYSIEYKTYGERDWVAKKGCQRITRKSCNLTVETGNLTELYYARVT 97

Query: 106 A-EKENTSSWYEVDSFTPFRKAQIGPPEVHLEAEDKAI--VIHISPGTKDSVMWALDGLS 162
           A      S+    D F+  +   + PP+V   ++ ++I  ++H +P    + + A DG  
Sbjct: 98  AVSAGGRSATKMTDRFSSLQHTTLKPPDVTCISKVRSIQMIVHPTP----TPIRAGDGHR 153

Query: 163 FTYSLVIWKNSSGVEERIENIYSRH--------KIYKLSPETTY 198
            T   +       +E ++   Y  H        + + L+P+T +
Sbjct: 154 LTLEDIFHDLFYHLELQVNRTYQMHLGGKQREYEFFGLTPDTEF 197


>gi|16418459 interleukin 22-binding protein isoform 1 [Homo sapiens]
          Length = 263

 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 40/159 (25%), Positives = 67/159 (42%), Gaps = 10/159 (6%)

Query: 276 KWKQIPDCENVKTTQCVFPQNVFQ-KGIYLLRVQASDGNNTSFWSEEIKFDTEIQAFLLP 334
           +WK   DC   +   C         +  Y  RV+A+   + S WS   +F    +  + P
Sbjct: 103 QWKNKEDCWGTQELSCDLTSETSDIQEPYYGRVRAASAGSYSEWSMTPRFTPWWETKIDP 162

Query: 335 PVFNIRSLSDSFHIYIGAP------KQSGNTPVIQDYPLIYEIIFWENTSNAERKIIE-K 387
           PV NI  ++ S  + + AP      ++  N  +   Y L+Y +    N+   E+K+ E  
Sbjct: 163 PVMNITQVNGSLLVILHAPNLPYRYQKEKNVSIEDYYELLYRVFIINNSLEKEQKVYEGA 222

Query: 388 KTDVTVPNLKPLTVYCVKARAHTMDEKLNKSSVFSDAVC 426
              V +  L P + YCV A  +     L++ S  S+  C
Sbjct: 223 HRAVEIEALTPHSSYCVVAEIY--QPMLDRRSQRSEERC 259



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 34/142 (23%), Positives = 61/142 (42%), Gaps = 8/142 (5%)

Query: 67  KTGMDNWIKLSGCQNITSTKCNFSSLKLNVYEEIKLRIRAEKENT-SSWYEVDSFTPFRK 125
           K G   W     C       C+ +S   ++ E    R+RA    + S W     FTP+ +
Sbjct: 98  KYGQRQWKNKEDCWGTQELSCDLTSETSDIQEPYYGRVRAASAGSYSEWSMTPRFTPWWE 157

Query: 126 AQIGPPEVHL-EAEDKAIVIHISPG-----TKDSVMWALDGLSFTYSLVIWKNSSGVEER 179
            +I PP +++ +     +VI  +P       K+  +   D     Y + I  NS   E++
Sbjct: 158 TKIDPPVMNITQVNGSLLVILHAPNLPYRYQKEKNVSIEDYYELLYRVFIINNSLEKEQK 217

Query: 180 I-ENIYSRHKIYKLSPETTYCL 200
           + E  +   +I  L+P ++YC+
Sbjct: 218 VYEGAHRAVEIEALTPHSSYCV 239


>gi|4557880 interferon gamma receptor 1 precursor [Homo sapiens]
          Length = 489

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 72/328 (21%), Positives = 127/328 (38%), Gaps = 41/328 (12%)

Query: 227 NELPPPENIEVSVQNQNYVLKWDYTYANM--TFQVQWLHAFLKRNPGNHLYKWKQIPDCE 284
           + +P P N+ +   N N ++ W+Y        F V+       +N G    +W  I  C 
Sbjct: 27  SSVPTPTNVTIESYNMNPIVYWEYQIMPQVPVFTVE------VKNYGVKNSEW--IDACI 78

Query: 285 NVKTTQCVFPQNVFQKGIYL-LRVQASDGNNTSFWSEEIKFDTEIQAFLLPPVFNIRS-- 341
           N+    C    +V      L +RV+A  G   S +++  +F       + PP  +IR   
Sbjct: 79  NISHHYCNISDHVGDPSNSLWVRVKARVGQKESAYAKSEEFAVCRDGKIGPPKLDIRKEE 138

Query: 342 ---LSDSFH--IYIGAPKQSGN-TPVIQDYPLIYEIIFWENTSNAERKIIEKKTD----- 390
              + D FH  +++   +Q  +  P    Y  +Y +    N S  + KI+ +K D     
Sbjct: 139 KQIMIDIFHPSVFVNGDEQEVDYDPETTCYIRVYNVYVRMNGSEIQYKILTQKEDDCDEI 198

Query: 391 ---VTVPNLKPLTVYCVKARA--HTMDEKLNKSSVFSDAVCEKTKPGNTSKIWLIVGICI 445
              + +P     + YCV A    H       KS      +   +  G+   +W+ V   +
Sbjct: 199 QCQLAIPVSSLNSQYCVSAEGVLHVWGVTTEKSKEVCITIFNSSIKGS---LWIPVVAAL 255

Query: 446 ALFALPFVIYAAKVFLRCINYVFFPS-LKPSSSID-------EYFSEQPLKNLLLSTSEE 497
            LF +  +++    +++ IN +   S + P S I        E   E    +L+ S    
Sbjct: 256 LLFLVLSLVFIC-FYIKKINPLKEKSIILPKSLISVVRSATLETKPESKYVSLITSYQPF 314

Query: 498 QIEKCFIIENISTIATVEETNQTDEDHK 525
            +EK  + E   + ATV   +  D   K
Sbjct: 315 SLEKEVVCEEPLSPATVPGMHTEDNPGK 342



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 31/126 (24%), Positives = 61/126 (48%), Gaps = 2/126 (1%)

Query: 22  SAAAGGKNLKSPQKVEVDIIDDNFILRWNRSDESVGNVTFSFDYQKTGMDNWIKLSGCQN 81
           +A  G  ++ +P  V ++  + N I+ W         V F+ + +  G+ N   +  C N
Sbjct: 21  TADLGPSSVPTPTNVTIESYNMNPIVYWEYQIMPQVPV-FTVEVKNYGVKNSEWIDACIN 79

Query: 82  ITSTKCNFSSLKLNVYEEIKLRIRAEK-ENTSSWYEVDSFTPFRKAQIGPPEVHLEAEDK 140
           I+   CN S    +    + +R++A   +  S++ + + F   R  +IGPP++ +  E+K
Sbjct: 80  ISHHYCNISDHVGDPSNSLWVRVKARVGQKESAYAKSEEFAVCRDGKIGPPKLDIRKEEK 139

Query: 141 AIVIHI 146
            I+I I
Sbjct: 140 QIMIDI 145


>gi|56676330 HP1-BP74 [Homo sapiens]
          Length = 553

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 32/107 (29%), Positives = 50/107 (46%), Gaps = 4/107 (3%)

Query: 449 ALPFVIYAAKVFLRCINYVFFPSLKPSSSIDEYFSEQPLKNLLLSTSEEQIEKCFIIENI 508
           ALP ++ A  +    +      S  P         E P K+ L    EE+ E    I + 
Sbjct: 15  ALPLIVGAQLIHADKLGEKVEDSTMPIRRTVNSTRETPPKSKLAEGEEEKPEPD--ISSE 72

Query: 509 STIATVEETNQTDEDHKKYSSQTSQDSGNYSNEDESESKTSEELQQD 555
            +++TVEE  Q +E     SS+  Q  G   NE++ E+K+SEE ++D
Sbjct: 73  ESVSTVEE--QENETPPATSSEAEQPKGEPENEEKEENKSSEETKKD 117


>gi|25014103 interleukin 28 receptor, alpha isoform 1 [Homo sapiens]
          Length = 520

 Score = 38.1 bits (87), Expect = 0.021
 Identities = 35/159 (22%), Positives = 63/159 (39%), Gaps = 7/159 (4%)

Query: 20  VLSAAAGGKNLKSPQKVEVDIIDDNFILRWNRSDESVGNVTFSFDYQKT-GMDNWIKLSG 78
           +L AA G   L  PQ V +   + +  L W     +  +VT+   YQ +     W ++  
Sbjct: 14  LLQAAPGRPRLAPPQNVTLLSQNFSVYLTWLPGLGNPQDVTYFVAYQSSPTRRRWREVEE 73

Query: 79  CQNITSTKCNFSSL-KLNVYEEIKLRIRAEKENTSS-WYEVDSFTPFRKAQIGPPEVHLE 136
           C       C+   L K ++Y + K R+R    ++ S W E +      + +  PP + L 
Sbjct: 74  CAGTKELLCSMMCLKKQDLYNKFKGRVRTVSPSSKSPWVESEYLDYLFEVEPAPPVLVLT 133

Query: 137 AEDKAIVIHISPGTKDSVMWALDGLSFTYSLVIWKNSSG 175
             ++     +S      +   +  L   Y +  WK  +G
Sbjct: 134 QTEEI----LSANATYQLPPCMPPLDLKYEVAFWKEGAG 168



 Score = 38.1 bits (87), Expect = 0.021
 Identities = 34/154 (22%), Positives = 64/154 (41%), Gaps = 20/154 (12%)

Query: 229 LPPPENIEVSVQNQNYVLKWDYTYAN---MTFQVQWLHAFLKRNPGNHLYKWKQIPDCEN 285
           L PP+N+ +  QN +  L W     N   +T+ V +  +  +R       +W+++ +C  
Sbjct: 24  LAPPQNVTLLSQNFSVYLTWLPGLGNPQDVTYFVAYQSSPTRR-------RWREVEECAG 76

Query: 286 VK----TTQCVFPQNVFQKGIYLLRVQASDGNNTSFWSEEIKFDTEIQAFLLPPVFNIRS 341
            K    +  C+  Q+++ K  +  RV+    ++ S W E    D   +    PPV  +  
Sbjct: 77  TKELLCSMMCLKKQDLYNK--FKGRVRTVSPSSKSPWVESEYLDYLFEVEPAPPVLVLTQ 134

Query: 342 LSDSFHIYIGAPKQSGNTPVIQDYPLIYEIIFWE 375
             +     + A       P +    L YE+ FW+
Sbjct: 135 TEE----ILSANATYQLPPCMPPLDLKYEVAFWK 164


>gi|28416911 interleukin 28 receptor, alpha isoform 3 [Homo sapiens]
          Length = 244

 Score = 38.1 bits (87), Expect = 0.021
 Identities = 35/159 (22%), Positives = 63/159 (39%), Gaps = 7/159 (4%)

Query: 20  VLSAAAGGKNLKSPQKVEVDIIDDNFILRWNRSDESVGNVTFSFDYQKT-GMDNWIKLSG 78
           +L AA G   L  PQ V +   + +  L W     +  +VT+   YQ +     W ++  
Sbjct: 14  LLQAAPGRPRLAPPQNVTLLSQNFSVYLTWLPGLGNPQDVTYFVAYQSSPTRRRWREVEE 73

Query: 79  CQNITSTKCNFSSL-KLNVYEEIKLRIRAEKENTSS-WYEVDSFTPFRKAQIGPPEVHLE 136
           C       C+   L K ++Y + K R+R    ++ S W E +      + +  PP + L 
Sbjct: 74  CAGTKELLCSMMCLKKQDLYNKFKGRVRTVSPSSKSPWVESEYLDYLFEVEPAPPVLVLT 133

Query: 137 AEDKAIVIHISPGTKDSVMWALDGLSFTYSLVIWKNSSG 175
             ++     +S      +   +  L   Y +  WK  +G
Sbjct: 134 QTEEI----LSANATYQLPPCMPPLDLKYEVAFWKEGAG 168



 Score = 38.1 bits (87), Expect = 0.021
 Identities = 34/154 (22%), Positives = 64/154 (41%), Gaps = 20/154 (12%)

Query: 229 LPPPENIEVSVQNQNYVLKWDYTYAN---MTFQVQWLHAFLKRNPGNHLYKWKQIPDCEN 285
           L PP+N+ +  QN +  L W     N   +T+ V +  +  +R       +W+++ +C  
Sbjct: 24  LAPPQNVTLLSQNFSVYLTWLPGLGNPQDVTYFVAYQSSPTRR-------RWREVEECAG 76

Query: 286 VK----TTQCVFPQNVFQKGIYLLRVQASDGNNTSFWSEEIKFDTEIQAFLLPPVFNIRS 341
            K    +  C+  Q+++ K  +  RV+    ++ S W E    D   +    PPV  +  
Sbjct: 77  TKELLCSMMCLKKQDLYNK--FKGRVRTVSPSSKSPWVESEYLDYLFEVEPAPPVLVLTQ 134

Query: 342 LSDSFHIYIGAPKQSGNTPVIQDYPLIYEIIFWE 375
             +     + A       P +    L YE+ FW+
Sbjct: 135 TEE----ILSANATYQLPPCMPPLDLKYEVAFWK 164


>gi|28416909 interleukin 28 receptor, alpha isoform 2 [Homo sapiens]
          Length = 491

 Score = 38.1 bits (87), Expect = 0.021
 Identities = 35/159 (22%), Positives = 63/159 (39%), Gaps = 7/159 (4%)

Query: 20  VLSAAAGGKNLKSPQKVEVDIIDDNFILRWNRSDESVGNVTFSFDYQKT-GMDNWIKLSG 78
           +L AA G   L  PQ V +   + +  L W     +  +VT+   YQ +     W ++  
Sbjct: 14  LLQAAPGRPRLAPPQNVTLLSQNFSVYLTWLPGLGNPQDVTYFVAYQSSPTRRRWREVEE 73

Query: 79  CQNITSTKCNFSSL-KLNVYEEIKLRIRAEKENTSS-WYEVDSFTPFRKAQIGPPEVHLE 136
           C       C+   L K ++Y + K R+R    ++ S W E +      + +  PP + L 
Sbjct: 74  CAGTKELLCSMMCLKKQDLYNKFKGRVRTVSPSSKSPWVESEYLDYLFEVEPAPPVLVLT 133

Query: 137 AEDKAIVIHISPGTKDSVMWALDGLSFTYSLVIWKNSSG 175
             ++     +S      +   +  L   Y +  WK  +G
Sbjct: 134 QTEEI----LSANATYQLPPCMPPLDLKYEVAFWKEGAG 168



 Score = 38.1 bits (87), Expect = 0.021
 Identities = 34/154 (22%), Positives = 64/154 (41%), Gaps = 20/154 (12%)

Query: 229 LPPPENIEVSVQNQNYVLKWDYTYAN---MTFQVQWLHAFLKRNPGNHLYKWKQIPDCEN 285
           L PP+N+ +  QN +  L W     N   +T+ V +  +  +R       +W+++ +C  
Sbjct: 24  LAPPQNVTLLSQNFSVYLTWLPGLGNPQDVTYFVAYQSSPTRR-------RWREVEECAG 76

Query: 286 VK----TTQCVFPQNVFQKGIYLLRVQASDGNNTSFWSEEIKFDTEIQAFLLPPVFNIRS 341
            K    +  C+  Q+++ K  +  RV+    ++ S W E    D   +    PPV  +  
Sbjct: 77  TKELLCSMMCLKKQDLYNK--FKGRVRTVSPSSKSPWVESEYLDYLFEVEPAPPVLVLTQ 134

Query: 342 LSDSFHIYIGAPKQSGNTPVIQDYPLIYEIIFWE 375
             +     + A       P +    L YE+ FW+
Sbjct: 135 TEE----ILSANATYQLPPCMPPLDLKYEVAFWK 164


>gi|218505787 protocadherin 15 isoform CD2-1 precursor [Homo sapiens]
          Length = 1790

 Score = 36.6 bits (83), Expect = 0.062
 Identities = 18/63 (28%), Positives = 36/63 (57%)

Query: 492  LSTSEEQIEKCFIIENISTIATVEETNQTDEDHKKYSSQTSQDSGNYSNEDESESKTSEE 551
            L   ++   K  + +  +T +TVE   ++  D+ +YS + S+ S + + E+ESES+T  E
Sbjct: 1579 LEEEDKDYLKLTLDQEEATESTVESEEESSSDYTEYSEEESEFSESETTEEESESETPSE 1638

Query: 552  LQQ 554
             ++
Sbjct: 1639 EEE 1641


>gi|157311649 neogenin homolog 1 [Homo sapiens]
          Length = 1461

 Score = 35.4 bits (80), Expect = 0.14
 Identities = 88/421 (20%), Positives = 165/421 (39%), Gaps = 57/421 (13%)

Query: 11  LVLVAVAPWVLSAAAGGKNLKSPQKVEVDIIDDNFI-LRWNR--SDESVGNVTFSFDYQK 67
           L+++  AP     A  G    +P+ V   ++   FI L W    SD    N+T+S  Y K
Sbjct: 425 LIILEHAP-----ATTGPLPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTK 479

Query: 68  TGM--DNWIKLSGCQNITSTKCNFSSLKLNVYEEIKLRIRAEKENTSSWYEVDSFTPFRK 125
            G+  +     S    +  T  N     + ++     R+ A+ ++ S     +S  P R 
Sbjct: 480 EGIARERVENTSHPGEMQVTIQNLMPATVYIF-----RVMAQNKHGSG----ESSAPLRV 530

Query: 126 AQIGPPEVHLEAEDKAIVIHISPGTKDSVMWAL----DGLSFTYSLVIWKNSSGVEERIE 181
                PEV L      +  + +  T  +V W      +G    Y L   +  +  E+ ++
Sbjct: 531 ET--QPEVQLPGPAPNLRAYAASPTSITVTWETPVSGNGEIQNYKLYYMEKGTDKEQDVD 588

Query: 182 NIYSRHKIYKLSPETTYCLKVKAALLTSWKIGVYSPVHCIKTTVENELPPPENIEVSVQN 241
                + I  L   T Y  +V A        GV +P   ++T  +     P+N+ + V+N
Sbjct: 589 VSSHSYTINGLKKYTEYSFRVVA--YNKHGPGVSTPDVAVRTLSDVPSAAPQNLSLEVRN 646

Query: 242 QNYVLKWDYTYANMT-------FQVQWLHAFLKRNPGNHLYKWKQIPDCENVKTTQCVFP 294
              ++      A  T       +++++  A  K +    L    Q+        +Q +  
Sbjct: 647 SKSIMIHWQPPAPATQNGQITGYKIRYRKASRKSDVTETLVSGTQL--------SQLI-- 696

Query: 295 QNVFQKGIYLLRVQASDGNNT---SFWSEEIKFDTEIQAFLLPPV---FNIRSLSDSFHI 348
           + + +   Y  RV A   N T   + W     F++++    +P V    ++R L  S  +
Sbjct: 697 EGLDRGTEYNFRVAALTINGTGPATDWLSAETFESDLDETRVPEVPSSLHVRPLVTSI-V 755

Query: 349 YIGAPKQSGNTPVIQDYPLIYEIIFWENTSNAER-KIIEKKTDVTVPNLKPLTVYCVKAR 407
               P ++ N  V++ Y + Y I     + +A+  K+  K+   T+ NL P + Y +  +
Sbjct: 756 VSWTPPENQNI-VVRGYAIGYGI----GSPHAQTIKVDYKQRYYTIENLDPSSHYVITLK 810

Query: 408 A 408
           A
Sbjct: 811 A 811



 Score = 33.1 bits (74), Expect = 0.69
 Identities = 30/123 (24%), Positives = 53/123 (43%), Gaps = 19/123 (15%)

Query: 295 QNVFQKGIYLLRVQASDGNNTSFWSEEIKFDTEIQAFLLPPVFNIRSLSDSFHIYIGAPK 354
           QN+    +Y+ RV A + + +   S  ++ +T+ +  L  P  N+R+       Y  +P 
Sbjct: 501 QNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNLRA-------YAASPT 553

Query: 355 Q---SGNTPV-----IQDYPLIYEIIFWENTSNAERKIIEKKTDVTVPNLKPLTVYCVKA 406
               +  TPV     IQ+Y L Y     E  ++ E+ +       T+  LK  T Y  + 
Sbjct: 554 SITVTWETPVSGNGEIQNYKLYY----MEKGTDKEQDVDVSSHSYTINGLKKYTEYSFRV 609

Query: 407 RAH 409
            A+
Sbjct: 610 VAY 612


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 34.7 bits (78), Expect = 0.24
 Identities = 26/104 (25%), Positives = 47/104 (45%), Gaps = 10/104 (9%)

Query: 38    VDIIDDNFILRWNRSDESVGNVTFSF--DYQKTGMDNWIKLSGCQNITSTKCNFSSLKLN 95
             VD+      L WN+ D   G+    +  +YQ+ G  +WIK    + +T+ +C  + L+  
Sbjct: 17419 VDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKF---KTVTNLECVVTGLQ-- 17473

Query: 96    VYEEIKLRIRAEKENTSSWYEVDSFTPFR-KAQIGPPEVHLEAE 138
               +    R R + EN       D+  P   + ++ PP V L+ +
Sbjct: 17474 --QGKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVK 17515


>gi|110349717 titin isoform novex-2 [Homo sapiens]
          Length = 27118

 Score = 34.7 bits (78), Expect = 0.24
 Identities = 26/104 (25%), Positives = 47/104 (45%), Gaps = 10/104 (9%)

Query: 38    VDIIDDNFILRWNRSDESVGNVTFSF--DYQKTGMDNWIKLSGCQNITSTKCNFSSLKLN 95
             VD+      L WN+ D   G+    +  +YQ+ G  +WIK    + +T+ +C  + L+  
Sbjct: 11114 VDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKF---KTVTNLECVVTGLQ-- 11168

Query: 96    VYEEIKLRIRAEKENTSSWYEVDSFTPFR-KAQIGPPEVHLEAE 138
               +    R R + EN       D+  P   + ++ PP V L+ +
Sbjct: 11169 --QGKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVK 11210


>gi|110349713 titin isoform novex-1 [Homo sapiens]
          Length = 27051

 Score = 34.7 bits (78), Expect = 0.24
 Identities = 26/104 (25%), Positives = 47/104 (45%), Gaps = 10/104 (9%)

Query: 38    VDIIDDNFILRWNRSDESVGNVTFSF--DYQKTGMDNWIKLSGCQNITSTKCNFSSLKLN 95
             VD+      L WN+ D   G+    +  +YQ+ G  +WIK    + +T+ +C  + L+  
Sbjct: 11047 VDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKF---KTVTNLECVVTGLQ-- 11101

Query: 96    VYEEIKLRIRAEKENTSSWYEVDSFTPFR-KAQIGPPEVHLEAE 138
               +    R R + EN       D+  P   + ++ PP V L+ +
Sbjct: 11102 --QGKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVK 11143


>gi|110349715 titin isoform N2-B [Homo sapiens]
          Length = 26926

 Score = 34.7 bits (78), Expect = 0.24
 Identities = 26/104 (25%), Positives = 47/104 (45%), Gaps = 10/104 (9%)

Query: 38    VDIIDDNFILRWNRSDESVGNVTFSF--DYQKTGMDNWIKLSGCQNITSTKCNFSSLKLN 95
             VD+      L WN+ D   G+    +  +YQ+ G  +WIK    + +T+ +C  + L+  
Sbjct: 10922 VDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKF---KTVTNLECVVTGLQ-- 10976

Query: 96    VYEEIKLRIRAEKENTSSWYEVDSFTPFR-KAQIGPPEVHLEAE 138
               +    R R + EN       D+  P   + ++ PP V L+ +
Sbjct: 10977 --QGKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVK 11018


>gi|222136575 interleukin 10 receptor, alpha precursor [Homo
           sapiens]
          Length = 578

 Score = 34.3 bits (77), Expect = 0.31
 Identities = 44/229 (19%), Positives = 89/229 (38%), Gaps = 11/229 (4%)

Query: 5   LLGATTLVLVAVAPWVLSAAAGGKNLKSPQKVEVDIIDDNFILRWNRSDESVGNVTFSFD 64
           +L    ++L A+    L + A G  L SP  V  +    + IL W        +  +   
Sbjct: 1   MLPCLVVLLAALLSLRLGSDAHGTELPSPPSVWFEAEFFHHILHWTPIPNQSESTCYEVA 60

Query: 65  YQKTGMDNWIKLSGCQNITSTKCNFSSLKLNVYEEIKLRIRA-EKENTSSWYEVDSFTPF 123
             + G+++W  +S C    S      +L L      + R+RA +    S+W   ++    
Sbjct: 61  LLRYGIESWNSISNCSQTLSYDLTAVTLDLYHSNGYRARVRAVDGSRHSNWTVTNTRFSV 120

Query: 124 RKAQIGPPEVHLEAEDKAIVIHIS-PGTK----DSVMWALDGLSFTYSLVIWK---NSSG 175
            +  +    V+LE  +  I+  I  P  K    +    ++      Y + I K   N + 
Sbjct: 121 DEVTLTVGSVNLEIHNGFILGKIQLPRPKMAPANDTYESIFSHFREYEIAIRKVPGNFTF 180

Query: 176 VEERIENIYSRHKIYKLSPETTYCLKVKAALLTSWKIGVYSPVHCIKTT 224
             ++++  +    +        +C++VK ++ +    G++S   CI  T
Sbjct: 181 THKKVK--HENFSLLTSGEVGEFCVQVKPSVASRSNKGMWSKEECISLT 227



 Score = 30.0 bits (66), Expect = 5.8
 Identities = 29/122 (23%), Positives = 50/122 (40%), Gaps = 14/122 (11%)

Query: 199 CLKVKAALLTSWKIGVYSPVHCIKTTVENELPPPENIEVSVQNQNYVLKWDYTYANMTFQ 258
           CL V  A L S ++G  S  H        ELP P ++    +  +++L W     N +  
Sbjct: 4   CLVVLLAALLSLRLG--SDAH------GTELPSPPSVWFEAEFFHHILHWT-PIPNQSES 54

Query: 259 VQWLHAFLKRNPGNHLYKWKQIPDC-ENVKTTQCVFPQNVFQKGIYLLRVQASDGNNTSF 317
             +  A L+      +  W  I +C + +         +++    Y  RV+A DG+  S 
Sbjct: 55  TCYEVALLRYG----IESWNSISNCSQTLSYDLTAVTLDLYHSNGYRARVRAVDGSRHSN 110

Query: 318 WS 319
           W+
Sbjct: 111 WT 112


>gi|4503641 coagulation factor III precursor [Homo sapiens]
          Length = 295

 Score = 34.3 bits (77), Expect = 0.31
 Identities = 20/90 (22%), Positives = 43/90 (47%), Gaps = 1/90 (1%)

Query: 367 LIYEIIFWENTSNAERKIIEKKTDVTVPNLKPLTVYCVKARAHTMDEKLNKSSVFSDAVC 426
           LIY + +W+++S+  +K  +  T+  + ++     YC   +A      +N+ S  S   C
Sbjct: 183 LIYTLYYWKSSSSG-KKTAKTNTNEFLIDVDKGENYCFSVQAVIPSRTVNRKSTDSPVEC 241

Query: 427 EKTKPGNTSKIWLIVGICIALFALPFVIYA 456
              + G   +I+ I+G  + +  +  +I A
Sbjct: 242 MGQEKGEFREIFYIIGAVVFVVIILVIILA 271


>gi|4506309 protein tyrosine phosphatase, receptor type, D isoform 1
           precursor [Homo sapiens]
          Length = 1912

 Score = 33.9 bits (76), Expect = 0.40
 Identities = 32/111 (28%), Positives = 46/111 (41%), Gaps = 6/111 (5%)

Query: 303 YLLRVQASDGNNTSFWSE---EIKFDTEIQAFLLPPVFNIRSLSDSFHIYIGAPKQSGNT 359
           Y+ R+ A   N   F  E   EI    E+       + +  + S S  +    P  +   
Sbjct: 891 YVFRLSAR--NKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERN 948

Query: 360 PVIQDYPLIYEIIFWENTSNAERKIIEKKTDVTVPNLKPLTVYCVKARAHT 410
            +I  Y L+Y  I        E+ I+   T +T+  LKP T Y VK RAHT
Sbjct: 949 GIITKYTLLYRDINIPLLP-MEQLIVPADTTMTLTGLKPDTTYDVKVRAHT 998


>gi|18860890 protein tyrosine phosphatase, receptor type, D isoform
           2 precursor [Homo sapiens]
          Length = 1899

 Score = 33.9 bits (76), Expect = 0.40
 Identities = 32/111 (28%), Positives = 46/111 (41%), Gaps = 6/111 (5%)

Query: 303 YLLRVQASDGNNTSFWSE---EIKFDTEIQAFLLPPVFNIRSLSDSFHIYIGAPKQSGNT 359
           Y+ R+ A   N   F  E   EI    E+       + +  + S S  +    P  +   
Sbjct: 878 YVFRLSAR--NKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERN 935

Query: 360 PVIQDYPLIYEIIFWENTSNAERKIIEKKTDVTVPNLKPLTVYCVKARAHT 410
            +I  Y L+Y  I        E+ I+   T +T+  LKP T Y VK RAHT
Sbjct: 936 GIITKYTLLYRDINIPLLP-MEQLIVPADTTMTLTGLKPDTTYDVKVRAHT 985


>gi|18860892 protein tyrosine phosphatase, receptor type, D isoform
           3 precursor [Homo sapiens]
          Length = 1903

 Score = 33.9 bits (76), Expect = 0.40
 Identities = 32/111 (28%), Positives = 46/111 (41%), Gaps = 6/111 (5%)

Query: 303 YLLRVQASDGNNTSFWSE---EIKFDTEIQAFLLPPVFNIRSLSDSFHIYIGAPKQSGNT 359
           Y+ R+ A   N   F  E   EI    E+       + +  + S S  +    P  +   
Sbjct: 882 YVFRLSAR--NKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERN 939

Query: 360 PVIQDYPLIYEIIFWENTSNAERKIIEKKTDVTVPNLKPLTVYCVKARAHT 410
            +I  Y L+Y  I        E+ I+   T +T+  LKP T Y VK RAHT
Sbjct: 940 GIITKYTLLYRDINIPLLP-MEQLIVPADTTMTLTGLKPDTTYDVKVRAHT 989


>gi|118918395 fibronectin type III domain containing 3A isoform 1
           [Homo sapiens]
          Length = 1198

 Score = 33.9 bits (76), Expect = 0.40
 Identities = 23/61 (37%), Positives = 33/61 (54%), Gaps = 5/61 (8%)

Query: 189 IYKLSPETTYCLKVKAALLTSWKIGVYSPVHCIKTTVENELPPPENIE-VSVQNQNYVLK 247
           I  L P+TTY ++++A  L S   G +S  H IK   +   P P  +E V+  +QN  LK
Sbjct: 915 INNLQPDTTYRIRIQA--LNSLGAGPFS--HMIKLKTKPLPPDPPRLECVAFSHQNLKLK 970

Query: 248 W 248
           W
Sbjct: 971 W 971


>gi|118918397 fibronectin type III domain containing 3A isoform 2
           [Homo sapiens]
          Length = 1142

 Score = 33.9 bits (76), Expect = 0.40
 Identities = 23/61 (37%), Positives = 33/61 (54%), Gaps = 5/61 (8%)

Query: 189 IYKLSPETTYCLKVKAALLTSWKIGVYSPVHCIKTTVENELPPPENIE-VSVQNQNYVLK 247
           I  L P+TTY ++++A  L S   G +S  H IK   +   P P  +E V+  +QN  LK
Sbjct: 859 INNLQPDTTYRIRIQA--LNSLGAGPFS--HMIKLKTKPLPPDPPRLECVAFSHQNLKLK 914

Query: 248 W 248
           W
Sbjct: 915 W 915


>gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo
           sapiens]
          Length = 1015

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 18/45 (40%), Positives = 25/45 (55%), Gaps = 1/45 (2%)

Query: 367 LIYEIIFWENTSNAERKIIE-KKTDVTVPNLKPLTVYCVKARAHT 410
           L YEI ++E        II+ K+T +T   LKP +VY  + RA T
Sbjct: 500 LEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQIRART 544


>gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo
           sapiens]
          Length = 1037

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 18/45 (40%), Positives = 25/45 (55%), Gaps = 1/45 (2%)

Query: 367 LIYEIIFWENTSNAERKIIE-KKTDVTVPNLKPLTVYCVKARAHT 410
           L YEI ++E        II+ K+T +T   LKP +VY  + RA T
Sbjct: 500 LEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQIRART 544


>gi|21361639 DIPB protein [Homo sapiens]
          Length = 344

 Score = 32.0 bits (71), Expect = 1.5
 Identities = 13/41 (31%), Positives = 25/41 (60%)

Query: 515 EETNQTDEDHKKYSSQTSQDSGNYSNEDESESKTSEELQQD 555
           EE ++T+E+ +  S + S++      EDE ES+  E+ Q++
Sbjct: 108 EEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEE 148


>gi|188497648 ubiquitin specific peptidase 37 [Homo sapiens]
          Length = 979

 Score = 32.0 bits (71), Expect = 1.5
 Identities = 21/83 (25%), Positives = 39/83 (46%), Gaps = 1/83 (1%)

Query: 473 KPSSSIDEYFSEQPLKNLLLSTSEEQIEKCFIIENISTIATVEETNQTDEDHKKYSSQTS 532
           KP+SS D  F+E  ++ +  +    + EK   I  +   +  E T   DE+ +  + + S
Sbjct: 731 KPTSSPDTGFAEDDIQEMPENPDTMETEKPKTITELDPASFTEITKDCDENKENKTPEGS 790

Query: 533 QDSGNYSNE-DESESKTSEELQQ 554
           Q   ++  + D    +  +ELQQ
Sbjct: 791 QGEVDWLQQYDMEREREEQELQQ 813


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.132    0.395 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,612,251
Number of Sequences: 37866
Number of extensions: 947006
Number of successful extensions: 3155
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 41
Number of HSP's that attempted gapping in prelim test: 3003
Number of HSP's gapped (non-prelim): 175
length of query: 557
length of database: 18,247,518
effective HSP length: 107
effective length of query: 450
effective length of database: 14,195,856
effective search space: 6388135200
effective search space used: 6388135200
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.