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Search of human proteins with 46249382
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|46249382 paired-like homeobox 2a [Homo sapiens]
(284 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|46249382 paired-like homeobox 2a [Homo sapiens] 589 e-169
gi|12707580 paired-like homeobox 2b [Homo sapiens] 280 1e-75
gi|239754062 PREDICTED: orthopedia homeobox [Homo sapiens] 120 1e-27
gi|14149760 orthopedia homeobox [Homo sapiens] 120 1e-27
gi|24497589 aristaless related homeobox [Homo sapiens] 119 4e-27
gi|122937484 dorsal root ganglia homeobox [Homo sapiens] 113 2e-25
gi|4557489 cone-rod homeobox protein [Homo sapiens] 110 2e-24
gi|7706659 paired related homeobox 2 [Homo sapiens] 109 3e-24
gi|14249388 retina and anterior neural fold homeobox 2 [Homo sap... 108 7e-24
gi|126116581 retina and anterior neural fold homeobox [Homo sapi... 107 1e-23
gi|113204604 aristaless-like homeobox 3 [Homo sapiens] 104 8e-23
gi|5902024 paired mesoderm homeobox 1 isoform pmx-1a [Homo sapiens] 104 1e-22
gi|12707577 paired mesoderm homeobox 1 isoform pmx-1b [Homo sapi... 104 1e-22
gi|188219638 paired box 3 isoform PAX3i [Homo sapiens] 103 1e-22
gi|31563348 paired box 3 isoform PAX3g [Homo sapiens] 103 1e-22
gi|31563346 paired box 3 isoform PAX3h [Homo sapiens] 103 1e-22
gi|31563344 paired box 3 isoform PAX3e [Homo sapiens] 103 1e-22
gi|31563342 paired box 3 isoform PAX3d [Homo sapiens] 103 1e-22
gi|31563340 paired box 3 isoform PAX3 [Homo sapiens] 103 1e-22
gi|55743092 aristaless-like homeobox 4 [Homo sapiens] 103 2e-22
gi|20070107 orthodenticle homeobox 1 [Homo sapiens] 103 2e-22
gi|154813201 cartilage paired-class homeoprotein 1 [Homo sapiens] 102 5e-22
gi|4826912 paired-like homeodomain 3 [Homo sapiens] 101 8e-22
gi|27436933 orthodenticle homeobox 2 isoform b [Homo sapiens] 100 1e-21
gi|11119420 orthodenticle homeobox 2 isoform a [Homo sapiens] 100 2e-21
gi|4505619 paired box 7 isoform 1 [Homo sapiens] 100 2e-21
gi|7524359 paired box 7 isoform 2 [Homo sapiens] 100 2e-21
gi|207029223 paired box 7 isoform 3 [Homo sapiens] 100 2e-21
gi|22218349 diencephalon/mesencephalon homeobox 1 isoform b [Hom... 99 6e-21
gi|27436936 diencephalon/mesencephalon homeobox 1 isoform a [Hom... 99 6e-21
>gi|46249382 paired-like homeobox 2a [Homo sapiens]
Length = 284
Score = 589 bits (1519), Expect = e-169
Identities = 284/284 (100%), Positives = 284/284 (100%)
Query: 1 MDYSYLNSYDSCVAAMEASAYGDFGACSQPGGFQYSPLRPAFPAAGPPCPALGSSNCALG 60
MDYSYLNSYDSCVAAMEASAYGDFGACSQPGGFQYSPLRPAFPAAGPPCPALGSSNCALG
Sbjct: 1 MDYSYLNSYDSCVAAMEASAYGDFGACSQPGGFQYSPLRPAFPAAGPPCPALGSSNCALG 60
Query: 61 ALRDHQPAPYSAVPYKFFPEPSGLHEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTR 120
ALRDHQPAPYSAVPYKFFPEPSGLHEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTR
Sbjct: 61 ALRDHQPAPYSAVPYKFFPEPSGLHEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTR 120
Query: 121 EELALKIDLTEARVQVWFQNRRAKFRKQERAASAKGAAGAAGAKKGEARCSSEDDDSKES 180
EELALKIDLTEARVQVWFQNRRAKFRKQERAASAKGAAGAAGAKKGEARCSSEDDDSKES
Sbjct: 121 EELALKIDLTEARVQVWFQNRRAKFRKQERAASAKGAAGAAGAKKGEARCSSEDDDSKES 180
Query: 181 TCSPTPDSTASLPPPPAPGLASPRLSPSPLPVALGSGPGPGPGPQPLKGALWAGVAGGGG 240
TCSPTPDSTASLPPPPAPGLASPRLSPSPLPVALGSGPGPGPGPQPLKGALWAGVAGGGG
Sbjct: 181 TCSPTPDSTASLPPPPAPGLASPRLSPSPLPVALGSGPGPGPGPQPLKGALWAGVAGGGG 240
Query: 241 GGPGAGAAELLKAWQPAESGPGPFSGVLSSFHRKPGPALKTNLF 284
GGPGAGAAELLKAWQPAESGPGPFSGVLSSFHRKPGPALKTNLF
Sbjct: 241 GGPGAGAAELLKAWQPAESGPGPFSGVLSSFHRKPGPALKTNLF 284
>gi|12707580 paired-like homeobox 2b [Homo sapiens]
Length = 314
Score = 280 bits (715), Expect = 1e-75
Identities = 171/311 (54%), Positives = 193/311 (62%), Gaps = 46/311 (14%)
Query: 1 MDYSYLNS--YDSCVAAME----ASAYGDFGACSQPGGFQYSPLRPAFPAAGPPCPALGS 54
M+YSYLNS Y+SC+A M+ ASAY DF +CSQ GFQY+P+R F A CP+L
Sbjct: 4 MEYSYLNSSAYESCMAGMDTSSLASAYADFSSCSQASGFQYNPIRTTFGATSG-CPSLTP 62
Query: 55 SNCALGALRDHQPAPYSAVPYKFFPEPSGLHEKRKQRRIRTTFTSAQLKELERVFAETHY 114
+C+LG LRDHQ +PY+AVPYK F + GL+EKRKQRRIRTTFTSAQLKELERVFAETHY
Sbjct: 63 GSCSLGTLRDHQSSPYAAVPYKLFTDHGGLNEKRKQRRIRTTFTSAQLKELERVFAETHY 122
Query: 115 PDIYTREELALKIDLTEARVQVWFQNRRAKFRKQERAASAKGAAGAAGAKKGEARCSSED 174
PDIYTREELALKIDLTEARVQVWFQNRRAKFRKQERAA+A AA A G+ SS D
Sbjct: 123 PDIYTREELALKIDLTEARVQVWFQNRRAKFRKQERAAAA-AAAAAKNGSSGKKSDSSRD 181
Query: 175 DDSKESTCSPTPDSTASLPPPPAP-----GLASPRLSPSPLPVALGSGPGPGPGPQPLKG 229
D+SKE+ S PDST P P P PSP +GPG GPG +P KG
Sbjct: 182 DESKEAK-STDPDSTGGPGPNPNPTPSCGANGGGGGGPSPAGAPGAAGPG-GPGGEPGKG 239
Query: 230 --------------ALWAGVAGG--GGGGPGAGAAELLKAWQPA--------ESGPGPFS 265
A A AGG GGPG G W P +S GPF+
Sbjct: 240 GAAAAAAAAAAAAAAAAAAAAGGLAAAGGPGQG-------WAPGPGPITSIPDSLGGPFA 292
Query: 266 GVLSSFHRKPG 276
VLSS R G
Sbjct: 293 SVLSSLQRPNG 303
>gi|239754062 PREDICTED: orthopedia homeobox [Homo sapiens]
Length = 325
Score = 120 bits (301), Expect = 1e-27
Identities = 94/266 (35%), Positives = 127/266 (47%), Gaps = 49/266 (18%)
Query: 28 SQPGGF------QYSPLRPAFPAAGPPCPALGSSNCALGALR---DHQPAPYSAVPYKFF 78
S PGG P+ A G +GS+ +L D QP P
Sbjct: 36 SDPGGHPGDLAPNSDPVEGATLLPGEDITTVGSTPASLAVSAKDPDKQPGPQGG------ 89
Query: 79 PEPSGLHEKR---KQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQ 135
P PS +++ KQ+R RT FT AQL ELER FA+THYPDI+ REELAL+I LTE+RVQ
Sbjct: 90 PNPSQAGQQQGQQKQKRHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLTESRVQ 149
Query: 136 VWFQNRRAKFRKQERAASA----------------KGAAGAAGAKKGEARCSSEDDDSKE 179
VWFQNRRAK++K+++ + AA AA A G++ CS +D++
Sbjct: 150 VWFQNRRAKWKKRKKTTNVFRAPGTLLPTPGLPQFPSAAAAAAAAMGDSLCSFHANDTRW 209
Query: 180 STCSPTPDSTASLPPPPAPGLASPRLSPSPLPVALGSGPGPGPGPQPLKGALWAGVAGGG 239
+ + + LP PPA G ++ S +L +GP P G++
Sbjct: 210 AAAA--MPGVSQLPLPPALG-RQQAMAQSLSQCSLAAGPPPNS----------MGLSNSL 256
Query: 240 GGGPGAGAAELLKAWQPAESGPGPFS 265
G GAG L +QPA G P S
Sbjct: 257 AGSNGAGLQSHL--YQPAFPGMVPAS 280
>gi|14149760 orthopedia homeobox [Homo sapiens]
Length = 325
Score = 120 bits (301), Expect = 1e-27
Identities = 94/266 (35%), Positives = 127/266 (47%), Gaps = 49/266 (18%)
Query: 28 SQPGGF------QYSPLRPAFPAAGPPCPALGSSNCALGALR---DHQPAPYSAVPYKFF 78
S PGG P+ A G +GS+ +L D QP P
Sbjct: 36 SDPGGHPGDLAPNSDPVEGATLLPGEDITTVGSTPASLAVSAKDPDKQPGPQGG------ 89
Query: 79 PEPSGLHEKR---KQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQ 135
P PS +++ KQ+R RT FT AQL ELER FA+THYPDI+ REELAL+I LTE+RVQ
Sbjct: 90 PNPSQAGQQQGQQKQKRHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLTESRVQ 149
Query: 136 VWFQNRRAKFRKQERAASA----------------KGAAGAAGAKKGEARCSSEDDDSKE 179
VWFQNRRAK++K+++ + AA AA A G++ CS +D++
Sbjct: 150 VWFQNRRAKWKKRKKTTNVFRAPGTLLPTPGLPQFPSAAAAAAAAMGDSLCSFHANDTRW 209
Query: 180 STCSPTPDSTASLPPPPAPGLASPRLSPSPLPVALGSGPGPGPGPQPLKGALWAGVAGGG 239
+ + + LP PPA G ++ S +L +GP P G++
Sbjct: 210 AAAA--MPGVSQLPLPPALG-RQQAMAQSLSQCSLAAGPPPNS----------MGLSNSL 256
Query: 240 GGGPGAGAAELLKAWQPAESGPGPFS 265
G GAG L +QPA G P S
Sbjct: 257 AGSNGAGLQSHL--YQPAFPGMVPAS 280
>gi|24497589 aristaless related homeobox [Homo sapiens]
Length = 562
Score = 119 bits (297), Expect = 4e-27
Identities = 82/189 (43%), Positives = 100/189 (52%), Gaps = 18/189 (9%)
Query: 87 KRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFR 146
KRKQRR RTTFTS QL+ELER F +THYPD++TREELA+++DLTEARVQVWFQNRRAK+R
Sbjct: 325 KRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWR 384
Query: 147 KQERAASAKGAAGA--AGAKKGEARCSSEDDDSKESTCSPTPDST------------ASL 192
K+E+A + G G S D S P DS SL
Sbjct: 385 KREKAGAQTHPPGLPFPGPLSATHPLSPYLDASPFPPHHPALDSAWTAAAAAAAAAFPSL 444
Query: 193 PPPPAPGLASPRLSPSPLPVALGSGPGPGPG-PQPLKGALWAGVAGGGGGGPGAGAAELL 251
PPPP P +P L LG+ P P G L++ +A + AA LL
Sbjct: 445 PPPPGSASLPPSGAPLGLSTFLGAAVFRHPAFISPAFGRLFSTMAPLTS---ASTAAALL 501
Query: 252 KAWQPAESG 260
+ PA G
Sbjct: 502 RQPTPAVEG 510
Score = 30.8 bits (68), Expect = 1.4
Identities = 29/100 (29%), Positives = 37/100 (37%), Gaps = 19/100 (19%)
Query: 147 KQERAASAKGAAGAAGAKKGEARCSSEDDDSKESTCSPTPDSTASLPPPPAPGLASPRLS 206
+ + A +A AA AA A + S S + S + +PPPP
Sbjct: 138 RPDGAGAAAAAAAAAAAAWDTLKISQAPQVSISRSKSYRENGAPFVPPPP---------- 187
Query: 207 PSPLPVALGSGPGPGPGPQPLKGALWAGVAGGGGGGPGAG 246
AL GPG P + GVAGG G P AG
Sbjct: 188 ------ALDELGGPGGVTHPEER---LGVAGGPGSAPAAG 218
>gi|122937484 dorsal root ganglia homeobox [Homo sapiens]
Length = 268
Score = 113 bits (283), Expect = 2e-25
Identities = 69/147 (46%), Positives = 84/147 (57%), Gaps = 20/147 (13%)
Query: 87 KRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFR 146
+RKQRR RTTFT QL+ LE VFA+THYPD++TREELA+KI+LTEARVQVWFQNRRAK+R
Sbjct: 35 RRKQRRNRTTFTLQQLEALEAVFAQTHYPDVFTREELAMKINLTEARVQVWFQNRRAKWR 94
Query: 147 KQERAASAKGAAGAAGAKKGEARCSSEDDDSKESTCSPTPDSTASLPPPPAPGLASPRLS 206
K ER A S ++ +KE TP ++ PP A +
Sbjct: 95 KTERGA------------------SDQEPGAKEPMAEVTPPPVRNINSPPPGDQARSKKE 136
Query: 207 PSPLPVALGSGPGP-GP-GPQPLKGAL 231
+LG GP GP P L G L
Sbjct: 137 ALEAQQSLGRTVGPAGPFFPSCLPGTL 163
>gi|4557489 cone-rod homeobox protein [Homo sapiens]
Length = 299
Score = 110 bits (274), Expect = 2e-24
Identities = 76/212 (35%), Positives = 105/212 (49%), Gaps = 28/212 (13%)
Query: 65 HQPAPYSAVPYKFFPEPSGLHEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELA 124
HQ PY + P RKQRR RTTFT +QL+ELE +FA+T YPD+Y REE+A
Sbjct: 27 HQAVPYPSAP-------------RKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVA 73
Query: 125 LKIDLTEARVQVWFQNRRAKFR--KQERAASAKGAAGAAGAKKGEARCSSEDDDSKESTC 182
LKI+L E+RVQVWF+NRRAK R +Q++ + G A A+ + + + S +
Sbjct: 74 LKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGGQAKARPAKRKAGTSPRPSTDVCP 133
Query: 183 SPTPDSTASLPPPPAPGLASPRLSPSPLPVALGSGPGPGPGPQPLKGALWAGVAGGGGGG 242
P S + PP P P SP + + V++ S P P+ + L A G
Sbjct: 134 DPLGISDSYSPPLPGPS-GSP--TTAVATVSIWSPASESPLPEAQRAGLVA-------SG 183
Query: 243 PGAGAAELLKAWQPAE---SGPGPFSGVLSSF 271
P +A + PA S P + S F
Sbjct: 184 PSLTSAPYAMTYAPASAFCSSPSAYGSPSSYF 215
>gi|7706659 paired related homeobox 2 [Homo sapiens]
Length = 253
Score = 109 bits (272), Expect = 3e-24
Identities = 62/127 (48%), Positives = 78/127 (61%), Gaps = 6/127 (4%)
Query: 82 SGLHEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNR 141
S K+KQRR RTTF S+QL+ LERVF THYPD + REELA +++L+EARVQVWFQNR
Sbjct: 96 SAAKRKKKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNR 155
Query: 142 RAKFRKQERAASAKGAAGAAGAKKGEARCSSEDDDSKESTCSP-----TPDSTASLPPPP 196
RAKFR+ ERA A +A + EA + + + SP T S S PP
Sbjct: 156 RAKFRRNERAMLASRSASLLKSYSQEA-AIEQPVAPRPTALSPDYLSWTASSPYSTVPPY 214
Query: 197 APGLASP 203
+PG + P
Sbjct: 215 SPGSSGP 221
>gi|14249388 retina and anterior neural fold homeobox 2 [Homo
sapiens]
Length = 184
Score = 108 bits (269), Expect = 7e-24
Identities = 66/149 (44%), Positives = 75/149 (50%), Gaps = 39/149 (26%)
Query: 87 KRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFR 146
K+K RR RTTFT+ QL +LER F +HYPD+Y+REELA K+ L E RVQVWFQNRRAK+R
Sbjct: 24 KKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAAKVHLPEVRVQVWFQNRRAKWR 83
Query: 147 KQERAASAKGAAGAAGAKKGEARCSSEDDDSKESTCSPTPDSTASLPPPPAPGLASPRLS 206
+QER S GA A LP PA A P
Sbjct: 84 RQERLESGSGAVAA-----------------------------PRLPEAPALPFARPPAM 114
Query: 207 PSPLPVALGSGP----------GPGPGPQ 225
PL LG GP GPGPG Q
Sbjct: 115 SLPLEPWLGPGPPAVPGLPRLLGPGPGLQ 143
>gi|126116581 retina and anterior neural fold homeobox [Homo
sapiens]
Length = 346
Score = 107 bits (267), Expect = 1e-23
Identities = 74/183 (40%), Positives = 93/183 (50%), Gaps = 37/183 (20%)
Query: 87 KRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFR 146
K+K RR RTTFT+ QL ELER F ++HYPD+Y+REELA K++L E RVQVWFQNRRAK+R
Sbjct: 133 KKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAGKVNLPEVRVQVWFQNRRAKWR 192
Query: 147 KQERAASAKGAAGAAGAKKGEARCSSEDDDSKESTCSPTPDSTASLPPPPAPGLASPRLS 206
+QE+ + S + DS + S +P P +
Sbjct: 193 RQEKLEVS----------------SMKLQDSPLLSFSRSP----------------PSAT 220
Query: 207 PSPLPVALGSGPGPGPGPQPLKGALWAGVAGGGGGG----PGAG-AAELLKAWQPAESGP 261
SPL GSG GP G PL+ L + GGG PG G A+ L A P
Sbjct: 221 LSPLGAGPGSGGGPAGGALPLESWLGPPLPGGGATALQSLPGFGPPAQSLPASYTPPPPP 280
Query: 262 GPF 264
PF
Sbjct: 281 PPF 283
Score = 30.8 bits (68), Expect = 1.4
Identities = 27/98 (27%), Positives = 36/98 (36%), Gaps = 21/98 (21%)
Query: 159 GAAGAKKGEARCSSEDDDSKESTCSPTPDSTASLPPPPAPGLASPRLSPSPLPVALGSGP 218
GA GAK+ + R + C P+ + PPPAP A +P P
Sbjct: 56 GARGAKERDRRLGARP------ACPKAPEEGSEPSPPPAPAPAPEYEAPRPYCPKEPGEA 109
Query: 219 GPGPGPQPLKGALWAGVAGGGGGGPGAGAAELLKAWQP 256
P PG P+ GP G A+L + QP
Sbjct: 110 RPSPG-LPV--------------GPATGEAKLSEEEQP 132
>gi|113204604 aristaless-like homeobox 3 [Homo sapiens]
Length = 343
Score = 104 bits (260), Expect = 8e-23
Identities = 70/177 (39%), Positives = 95/177 (53%), Gaps = 11/177 (6%)
Query: 87 KRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFR 146
K K+RR RTTF++ QL+ELE+VF +THYPD+Y RE+LAL+ DLTEARVQVWFQNRRAK+R
Sbjct: 150 KSKKRRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWR 209
Query: 147 KQERAAS-AKGAAGAAGAKKGEARCSSEDDDSKESTCSPTPDSTASLPPPPAPGLASPRL 205
K+ER +G A ++ +++ +P S + P P L SP
Sbjct: 210 KRERYGKIQEGRNPFTAAYDISVLPRTDSHPQLQNSLWASPGSGS----PGGPCLVSPEG 265
Query: 206 SPSPL--PVALGSGPGPGPGPQPLKGALWAGVAGGGGGGPGAGAAELLKAWQPAESG 260
PSP P + G G P A G+ G P G +++P+ G
Sbjct: 266 IPSPCMSPYSHPHGSVAGFMGVPAPSAAHPGIYSIHGFPPTLGG----HSFEPSSDG 318
>gi|5902024 paired mesoderm homeobox 1 isoform pmx-1a [Homo sapiens]
Length = 217
Score = 104 bits (259), Expect = 1e-22
Identities = 51/82 (62%), Positives = 62/82 (75%)
Query: 86 EKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKF 145
+KRKQRR RTTF S+QL+ LERVF THYPD + RE+LA +++LTEARVQVWFQNRRAKF
Sbjct: 90 KKRKQRRNRTTFNSSQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVWFQNRRAKF 149
Query: 146 RKQERAASAKGAAGAAGAKKGE 167
R+ ERA A A + G+
Sbjct: 150 RRNERAMLANKNASLLKSYSGD 171
>gi|12707577 paired mesoderm homeobox 1 isoform pmx-1b [Homo
sapiens]
Length = 245
Score = 104 bits (259), Expect = 1e-22
Identities = 51/82 (62%), Positives = 62/82 (75%)
Query: 86 EKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKF 145
+KRKQRR RTTF S+QL+ LERVF THYPD + RE+LA +++LTEARVQVWFQNRRAKF
Sbjct: 90 KKRKQRRNRTTFNSSQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVWFQNRRAKF 149
Query: 146 RKQERAASAKGAAGAAGAKKGE 167
R+ ERA A A + G+
Sbjct: 150 RRNERAMLANKNASLLKSYSGD 171
>gi|188219638 paired box 3 isoform PAX3i [Homo sapiens]
Length = 483
Score = 103 bits (258), Expect = 1e-22
Identities = 57/92 (61%), Positives = 63/92 (68%), Gaps = 1/92 (1%)
Query: 60 GALRDHQPAPYSAVPYKFFPEPSGLHEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYT 119
G L + AP S EP L KRKQRR RTTFT+ QL+ELER F THYPDIYT
Sbjct: 189 GILSERASAPQSDEGSDIDSEPD-LPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYT 247
Query: 120 REELALKIDLTEARVQVWFQNRRAKFRKQERA 151
REELA + LTEARVQVWF NRRA++RKQ A
Sbjct: 248 REELAQRAKLTEARVQVWFSNRRARWRKQAGA 279
>gi|31563348 paired box 3 isoform PAX3g [Homo sapiens]
Length = 403
Score = 103 bits (258), Expect = 1e-22
Identities = 57/92 (61%), Positives = 63/92 (68%), Gaps = 1/92 (1%)
Query: 60 GALRDHQPAPYSAVPYKFFPEPSGLHEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYT 119
G L + AP S EP L KRKQRR RTTFT+ QL+ELER F THYPDIYT
Sbjct: 190 GILSERASAPQSDEGSDIDSEPD-LPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYT 248
Query: 120 REELALKIDLTEARVQVWFQNRRAKFRKQERA 151
REELA + LTEARVQVWF NRRA++RKQ A
Sbjct: 249 REELAQRAKLTEARVQVWFSNRRARWRKQAGA 280
>gi|31563346 paired box 3 isoform PAX3h [Homo sapiens]
Length = 407
Score = 103 bits (258), Expect = 1e-22
Identities = 57/92 (61%), Positives = 63/92 (68%), Gaps = 1/92 (1%)
Query: 60 GALRDHQPAPYSAVPYKFFPEPSGLHEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYT 119
G L + AP S EP L KRKQRR RTTFT+ QL+ELER F THYPDIYT
Sbjct: 190 GILSERASAPQSDEGSDIDSEPD-LPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYT 248
Query: 120 REELALKIDLTEARVQVWFQNRRAKFRKQERA 151
REELA + LTEARVQVWF NRRA++RKQ A
Sbjct: 249 REELAQRAKLTEARVQVWFSNRRARWRKQAGA 280
>gi|31563344 paired box 3 isoform PAX3e [Homo sapiens]
Length = 505
Score = 103 bits (258), Expect = 1e-22
Identities = 57/92 (61%), Positives = 63/92 (68%), Gaps = 1/92 (1%)
Query: 60 GALRDHQPAPYSAVPYKFFPEPSGLHEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYT 119
G L + AP S EP L KRKQRR RTTFT+ QL+ELER F THYPDIYT
Sbjct: 190 GILSERASAPQSDEGSDIDSEPD-LPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYT 248
Query: 120 REELALKIDLTEARVQVWFQNRRAKFRKQERA 151
REELA + LTEARVQVWF NRRA++RKQ A
Sbjct: 249 REELAQRAKLTEARVQVWFSNRRARWRKQAGA 280
>gi|31563342 paired box 3 isoform PAX3d [Homo sapiens]
Length = 484
Score = 103 bits (258), Expect = 1e-22
Identities = 57/92 (61%), Positives = 63/92 (68%), Gaps = 1/92 (1%)
Query: 60 GALRDHQPAPYSAVPYKFFPEPSGLHEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYT 119
G L + AP S EP L KRKQRR RTTFT+ QL+ELER F THYPDIYT
Sbjct: 190 GILSERASAPQSDEGSDIDSEPD-LPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYT 248
Query: 120 REELALKIDLTEARVQVWFQNRRAKFRKQERA 151
REELA + LTEARVQVWF NRRA++RKQ A
Sbjct: 249 REELAQRAKLTEARVQVWFSNRRARWRKQAGA 280
>gi|31563340 paired box 3 isoform PAX3 [Homo sapiens]
Length = 479
Score = 103 bits (258), Expect = 1e-22
Identities = 57/92 (61%), Positives = 63/92 (68%), Gaps = 1/92 (1%)
Query: 60 GALRDHQPAPYSAVPYKFFPEPSGLHEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYT 119
G L + AP S EP L KRKQRR RTTFT+ QL+ELER F THYPDIYT
Sbjct: 190 GILSERASAPQSDEGSDIDSEPD-LPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYT 248
Query: 120 REELALKIDLTEARVQVWFQNRRAKFRKQERA 151
REELA + LTEARVQVWF NRRA++RKQ A
Sbjct: 249 REELAQRAKLTEARVQVWFSNRRARWRKQAGA 280
>gi|55743092 aristaless-like homeobox 4 [Homo sapiens]
Length = 411
Score = 103 bits (257), Expect = 2e-22
Identities = 48/64 (75%), Positives = 58/64 (90%)
Query: 87 KRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFR 146
K K+RR RTTFTS QL+ELE+VF +THYPD+Y RE+LA++ DLTEARVQVWFQNRRAK+R
Sbjct: 211 KGKKRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQNRRAKWR 270
Query: 147 KQER 150
K+ER
Sbjct: 271 KRER 274
>gi|20070107 orthodenticle homeobox 1 [Homo sapiens]
Length = 354
Score = 103 bits (256), Expect = 2e-22
Identities = 66/162 (40%), Positives = 89/162 (54%), Gaps = 22/162 (13%)
Query: 88 RKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRK 147
RKQRR RTTFT +QL LE +FA+T YPDI+ REE+ALKI+L E+RVQVWF+NRRAK R+
Sbjct: 36 RKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 95
Query: 148 QERAASA---------------KGAAGAAGAKKGEARCSSEDDDSKESTCSPTPDSTASL 192
Q+++ S + ++G A SS S S+ S P + A+
Sbjct: 96 QQQSGSGTKSRPAKKKSSPVRESSGSESSGQFTPPAVSSSASSSSSASSSSANPAAAAAA 155
Query: 193 -----PPPPAPGLASPRLSP--SPLPVALGSGPGPGPGPQPL 227
P A L++P S SP ++ GS P P+PL
Sbjct: 156 GLGGNPVAAASSLSTPAASSIWSPASISPGSAPASVSVPEPL 197
>gi|154813201 cartilage paired-class homeoprotein 1 [Homo sapiens]
Length = 326
Score = 102 bits (253), Expect = 5e-22
Identities = 47/62 (75%), Positives = 57/62 (91%)
Query: 89 KQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRKQ 148
K+RR RTTFTS QL+ELE+VF +THYPD+Y RE+LAL+ +LTEARVQVWFQNRRAK+RK+
Sbjct: 131 KKRRHRTTFTSLQLEELEKVFQKTHYPDVYVREQLALRTELTEARVQVWFQNRRAKWRKR 190
Query: 149 ER 150
ER
Sbjct: 191 ER 192
>gi|4826912 paired-like homeodomain 3 [Homo sapiens]
Length = 302
Score = 101 bits (251), Expect = 8e-22
Identities = 83/218 (38%), Positives = 104/218 (47%), Gaps = 24/218 (11%)
Query: 45 AGPPCPALGSSNCALGALRDHQPAPYSAVPYKFFPEPSGLHEKRKQRRIRTTFTSAQLKE 104
AG P P L C D + A S PE L K+KQRR RT FTS QL+E
Sbjct: 21 AGTPHPQLPEHGCKGQEHSDSEKASASLPGGS--PEDGSL--KKKQRRQRTHFTSQQLQE 76
Query: 105 LERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRKQERAASAKGAAGAAGAK 164
LE F YPD+ TREE+A+ +LTEARV+VWF+NRRAK+RK+ER+ A+ G+ A
Sbjct: 77 LEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERSQQAELCKGSFAAP 136
Query: 165 KGEARCSSEDDDSKESTCSPTPDSTASLPPPPA-------------PGLASPRLS-PSPL 210
G E+ S + P + A PP A P + P S PS +
Sbjct: 137 LGGLVPPYEEVYPGYSYGNWPPKALA--PPLAAKTFPFAFNSVNVGPLASQPVFSPPSSI 194
Query: 211 PVALGSGPGPGPGPQPLKGALWAGVAGGGGGGPGAGAA 248
++ PG P GAL G GGG PG A
Sbjct: 195 AASMVPSAAAAPGTVPGPGAL----QGLGGGPPGLAPA 228
>gi|27436933 orthodenticle homeobox 2 isoform b [Homo sapiens]
Length = 289
Score = 100 bits (250), Expect = 1e-21
Identities = 74/183 (40%), Positives = 92/183 (50%), Gaps = 28/183 (15%)
Query: 47 PPCPALGSSNCALGALRDHQPAPYSAVPYKFFPEPSGLHEKRKQRRIRTTFTSAQLKELE 106
PP G S G H Y A P RKQRR RTTFT AQL LE
Sbjct: 8 PPYAVNGLSLTTSGMDLLHPSVGYPATP-------------RKQRRERTTFTRAQLDVLE 54
Query: 107 RVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRKQERAASAKGAAGAAGAKKG 166
+FA+T YPDI+ REE+ALKI+L E+RVQVWF+NRRAK R+Q++ G AKK
Sbjct: 55 ALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAKK- 113
Query: 167 EARCSSEDDDSKESTCSP--TPDSTASLPPPPAPGLASPRLSPSPLPVALGSGPGPGPGP 224
+ S + S ES S TP S+ S+ P ++ S PV++ S P
Sbjct: 114 --KTSPAREVSSESGTSGQFTPPSSTSV----------PTIASSSAPVSIWSPASISPLS 161
Query: 225 QPL 227
PL
Sbjct: 162 DPL 164
>gi|11119420 orthodenticle homeobox 2 isoform a [Homo sapiens]
Length = 297
Score = 100 bits (248), Expect = 2e-21
Identities = 65/142 (45%), Positives = 83/142 (58%), Gaps = 15/142 (10%)
Query: 88 RKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRK 147
RKQRR RTTFT AQL LE +FA+T YPDI+ REE+ALKI+L E+RVQVWF+NRRAK R+
Sbjct: 44 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 103
Query: 148 QERAASAKGAAGAAGAKKGEARCSSEDDDSKESTCSP--TPDSTASLPPPPAPGLASPRL 205
Q++ G AKK + S + S ES S TP S+ S+ P +
Sbjct: 104 QQQQQQNGGQNKVRPAKK---KTSPAREVSSESGTSGQFTPPSSTSV----------PTI 150
Query: 206 SPSPLPVALGSGPGPGPGPQPL 227
+ S PV++ S P PL
Sbjct: 151 ASSSAPVSIWSPASISPLSDPL 172
>gi|4505619 paired box 7 isoform 1 [Homo sapiens]
Length = 520
Score = 99.8 bits (247), Expect = 2e-21
Identities = 48/65 (73%), Positives = 54/65 (83%)
Query: 87 KRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFR 146
KRKQRR RTTFT+ QL+ELE+ F THYPDIYTREELA + LTEARVQVWF NRRA++R
Sbjct: 214 KRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWR 273
Query: 147 KQERA 151
KQ A
Sbjct: 274 KQAGA 278
>gi|7524359 paired box 7 isoform 2 [Homo sapiens]
Length = 518
Score = 99.8 bits (247), Expect = 2e-21
Identities = 48/65 (73%), Positives = 54/65 (83%)
Query: 87 KRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFR 146
KRKQRR RTTFT+ QL+ELE+ F THYPDIYTREELA + LTEARVQVWF NRRA++R
Sbjct: 212 KRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWR 271
Query: 147 KQERA 151
KQ A
Sbjct: 272 KQAGA 276
>gi|207029223 paired box 7 isoform 3 [Homo sapiens]
Length = 505
Score = 99.8 bits (247), Expect = 2e-21
Identities = 48/65 (73%), Positives = 54/65 (83%)
Query: 87 KRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFR 146
KRKQRR RTTFT+ QL+ELE+ F THYPDIYTREELA + LTEARVQVWF NRRA++R
Sbjct: 214 KRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWR 273
Query: 147 KQERA 151
KQ A
Sbjct: 274 KQAGA 278
>gi|22218349 diencephalon/mesencephalon homeobox 1 isoform b [Homo
sapiens]
Length = 382
Score = 98.6 bits (244), Expect = 6e-21
Identities = 65/182 (35%), Positives = 84/182 (46%), Gaps = 26/182 (14%)
Query: 86 EKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKF 145
+ RKQRR RT FT+ QL+ LE+ F +THYPD+ RE LA+ +L EARVQVWF+NRRAKF
Sbjct: 67 QHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKF 126
Query: 146 RKQERA------ASAKGAAGAAGAKKGEARCSSEDDD--------------------SKE 179
RK++R+ K A G+ G K EA D S++
Sbjct: 127 RKKQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPGSDPPAELHLSLSEQ 186
Query: 180 STCSPTPDSTASLPPPPAPGLASPRLSPSPLPVALGSGPGPGPGPQPLKGALWAGVAGGG 239
S P+ P G P+ SP + G G G G+L G
Sbjct: 187 SASESAPEDQPDREEDPRAGAEDPKAEKSPGADSKGLGCKRGSPKADSPGSLTITPVAPG 246
Query: 240 GG 241
GG
Sbjct: 247 GG 248
>gi|27436936 diencephalon/mesencephalon homeobox 1 isoform a [Homo
sapiens]
Length = 377
Score = 98.6 bits (244), Expect = 6e-21
Identities = 65/182 (35%), Positives = 84/182 (46%), Gaps = 26/182 (14%)
Query: 86 EKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKF 145
+ RKQRR RT FT+ QL+ LE+ F +THYPD+ RE LA+ +L EARVQVWF+NRRAKF
Sbjct: 62 QHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKF 121
Query: 146 RKQERA------ASAKGAAGAAGAKKGEARCSSEDDD--------------------SKE 179
RK++R+ K A G+ G K EA D S++
Sbjct: 122 RKKQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPGSDPPAELHLSLSEQ 181
Query: 180 STCSPTPDSTASLPPPPAPGLASPRLSPSPLPVALGSGPGPGPGPQPLKGALWAGVAGGG 239
S P+ P G P+ SP + G G G G+L G
Sbjct: 182 SASESAPEDQPDREEDPRAGAEDPKAEKSPGADSKGLGCKRGSPKADSPGSLTITPVAPG 241
Query: 240 GG 241
GG
Sbjct: 242 GG 243
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.133 0.413
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,095,558
Number of Sequences: 37866
Number of extensions: 1207921
Number of successful extensions: 17469
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 734
Number of HSP's successfully gapped in prelim test: 1131
Number of HSP's that attempted gapping in prelim test: 9352
Number of HSP's gapped (non-prelim): 6922
length of query: 284
length of database: 18,247,518
effective HSP length: 101
effective length of query: 183
effective length of database: 14,423,052
effective search space: 2639418516
effective search space used: 2639418516
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.