Guide to the Human Genome
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Name: OTX2 Sequence: fasta or formatted (289aa) NCBI GI: 27436933
Description:

orthodenticle homeobox 2 isoform b

Referenced in:

Homeobox and Related Proteins
Stem Cells and Early Development

Other entries for this name:
alt prot [297aa] orthodenticle homeobox 2 isoform a
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.9         20           1
 C cysteine            1.7          5           1
 D aspartate           3.8         11           1
 E glutamate           2.4          7           2
 F phenylalanine       3.1          9           1
 G glycine             6.6         19           2
 H histidine           1.4          4           2
 I isoleucine          1.7          5           1
 K lysine              4.8         14           3
 L leucine             7.6         22           2
 M methionine          3.1          9           2
 N asparagine          3.5         10           1
 P proline             7.6         22           2
 Q glutamine           7.6         22           7
 R arginine            4.8         14           2
 S serine             14.5         42           3
 T threonine           8.7         25           2
 V valine              4.2         12           1
 W tryptophan          1.4          4           1
 Y tyrosine            4.5         13           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   orthodenticle homeobox 2 isoform b 
OTX2                  0.988   orthodenticle homeobox 2 isoform a 
OTX1                  0.548   orthodenticle homeobox 1 
CRX                   0.427   cone-rod homeobox protein 
ARGFX                 0.135   arginine-fifty homeobox 
PHOX2A                0.133   paired-like homeobox 2a 
DRGX                  0.126   dorsal root ganglia homeobox 
PHOX2B                0.124   paired-like homeobox 2b 
PAX6                  0.121   paired box gene 6 isoform a 
PAX6                  0.121   paired box gene 6 isoform b 
PAX6                  0.121   paired box gene 6 isoform a 
DMBX1                 0.119   diencephalon/mesencephalon homeobox 1 isoform a [Hom...
DMBX1                 0.119   diencephalon/mesencephalon homeobox 1 isoform b [Hom...
PITX1                 0.117   paired-like homeodomain transcription factor 1 [Hom...
PAX3                  0.117   paired box 3 isoform PAX3h 
SHOX                  0.115   short stature homeobox isoform SHOXb 
SHOX                  0.115   short stature homeobox isoform SHOXa 
PAX3                  0.115   paired box 3 isoform PAX3i 
PAX3                  0.115   paired box 3 isoform PAX3e 
PAX3                  0.115   paired box 3 isoform PAX3d 
PAX3                  0.115   paired box 3 isoform PAX3 
SHOX2                 0.113   short stature homeobox 2 isoform a 
SHOX2                 0.113   short stature homeobox 2 isoform b 
PRRX2                 0.113   paired related homeobox 2 
PAX3                  0.112   paired box 3 isoform PAX3g 
OTP                   0.112   PREDICTED: orthopedia homeobox 
OTP                   0.112   orthopedia homeobox 
ISX                   0.110   intestine-specific homeobox 
RAX                   0.108   retina and anterior neural fold homeobox 
PRRX1                 0.108   paired mesoderm homeobox 1 isoform pmx-1b 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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