Guide to the Human Genome
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Search of human proteins with 4580424

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4580424 paired box gene 6 isoform b [Homo sapiens]
         (436 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4580424 paired box gene 6 isoform b [Homo sapiens]                 889   0.0  
gi|189083681 paired box gene 6 isoform a [Homo sapiens]               852   0.0  
gi|4505615 paired box gene 6 isoform a [Homo sapiens]                 852   0.0  
gi|7524359 paired box 7 isoform 2 [Homo sapiens]                      252   4e-67
gi|188219638 paired box 3 isoform PAX3i [Homo sapiens]                250   2e-66
gi|4505619 paired box 7 isoform 1 [Homo sapiens]                      247   1e-65
gi|207029223 paired box 7 isoform 3 [Homo sapiens]                    247   1e-65
gi|31563344 paired box 3 isoform PAX3e [Homo sapiens]                 245   5e-65
gi|31563342 paired box 3 isoform PAX3d [Homo sapiens]                 245   5e-65
gi|31563340 paired box 3 isoform PAX3 [Homo sapiens]                  245   5e-65
gi|31563348 paired box 3 isoform PAX3g [Homo sapiens]                 244   9e-65
gi|31563346 paired box 3 isoform PAX3h [Homo sapiens]                 244   9e-65
gi|170784824 paired box 4 [Homo sapiens]                              235   7e-62
gi|34878709 paired box protein 2 isoform c [Homo sapiens]             230   2e-60
gi|34878716 paired box protein 2 isoform d [Homo sapiens]             226   4e-59
gi|34878701 paired box protein 2 isoform b [Homo sapiens]             226   4e-59
gi|34878699 paired box protein 2 isoform a [Homo sapiens]             220   2e-57
gi|34878703 paired box protein 2 isoform e [Homo sapiens]             220   2e-57
gi|5803117 paired box 8 isoform PAX8A [Homo sapiens]                  217   1e-56
gi|9951920 paired box 5 [Homo sapiens]                                215   6e-56
gi|7524365 paired box 8 isoform PAX8D [Homo sapiens]                  213   4e-55
gi|7669542 paired box 8 isoform PAX8E [Homo sapiens]                  213   4e-55
gi|7524363 paired box 8 isoform PAX8C [Homo sapiens]                  213   4e-55
gi|7524361 paired box 8 isoform PAX8B [Homo sapiens]                  213   4e-55
gi|197276661 paired box 1 [Homo sapiens]                              173   3e-43
gi|7242167 paired box 9 [Homo sapiens]                                172   7e-43
gi|7524356 paired box 3 isoform PAX3b [Homo sapiens]                  164   2e-40
gi|6654638 paired box 3 isoform PAX3a [Homo sapiens]                  164   2e-40
gi|126116581 retina and anterior neural fold homeobox [Homo sapi...   109   4e-24
gi|12707577 paired mesoderm homeobox 1 isoform pmx-1b [Homo sapi...   108   1e-23

>gi|4580424 paired box gene 6 isoform b [Homo sapiens]
          Length = 436

 Score =  889 bits (2297), Expect = 0.0
 Identities = 436/436 (100%), Positives = 436/436 (100%)

Query: 1   MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNQ 60
           MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNQ
Sbjct: 1   MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNQ 60

Query: 61  NVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRL 120
           NVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRL
Sbjct: 61  NVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRL 120

Query: 121 LSEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGT 180
           LSEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGT
Sbjct: 121 LSEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGT 180

Query: 181 SVPGQPTQDGCQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALE 240
           SVPGQPTQDGCQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALE
Sbjct: 181 SVPGQPTQDGCQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALE 240

Query: 241 KEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIP 300
           KEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIP
Sbjct: 241 KEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIP 300

Query: 301 ISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPP 360
           ISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPP
Sbjct: 301 ISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPP 360

Query: 361 VPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTSTGLISPGVSVPVQ 420
           VPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTSTGLISPGVSVPVQ
Sbjct: 361 VPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTSTGLISPGVSVPVQ 420

Query: 421 VPGSEPDMSQYWPRLQ 436
           VPGSEPDMSQYWPRLQ
Sbjct: 421 VPGSEPDMSQYWPRLQ 436


>gi|189083681 paired box gene 6 isoform a [Homo sapiens]
          Length = 422

 Score =  852 bits (2200), Expect = 0.0
 Identities = 422/436 (96%), Positives = 422/436 (96%), Gaps = 14/436 (3%)

Query: 1   MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNQ 60
           MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQ             
Sbjct: 1   MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQ------------- 47

Query: 61  NVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRL 120
            VSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRL
Sbjct: 48  -VSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRL 106

Query: 121 LSEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGT 180
           LSEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGT
Sbjct: 107 LSEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGT 166

Query: 181 SVPGQPTQDGCQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALE 240
           SVPGQPTQDGCQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALE
Sbjct: 167 SVPGQPTQDGCQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALE 226

Query: 241 KEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIP 300
           KEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIP
Sbjct: 227 KEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIP 286

Query: 301 ISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPP 360
           ISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPP
Sbjct: 287 ISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPP 346

Query: 361 VPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTSTGLISPGVSVPVQ 420
           VPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTSTGLISPGVSVPVQ
Sbjct: 347 VPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTSTGLISPGVSVPVQ 406

Query: 421 VPGSEPDMSQYWPRLQ 436
           VPGSEPDMSQYWPRLQ
Sbjct: 407 VPGSEPDMSQYWPRLQ 422


>gi|4505615 paired box gene 6 isoform a [Homo sapiens]
          Length = 422

 Score =  852 bits (2200), Expect = 0.0
 Identities = 422/436 (96%), Positives = 422/436 (96%), Gaps = 14/436 (3%)

Query: 1   MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNQ 60
           MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQ             
Sbjct: 1   MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQ------------- 47

Query: 61  NVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRL 120
            VSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRL
Sbjct: 48  -VSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRL 106

Query: 121 LSEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGT 180
           LSEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGT
Sbjct: 107 LSEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGT 166

Query: 181 SVPGQPTQDGCQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALE 240
           SVPGQPTQDGCQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALE
Sbjct: 167 SVPGQPTQDGCQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALE 226

Query: 241 KEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIP 300
           KEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIP
Sbjct: 227 KEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIP 286

Query: 301 ISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPP 360
           ISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPP
Sbjct: 287 ISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPP 346

Query: 361 VPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTSTGLISPGVSVPVQ 420
           VPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTSTGLISPGVSVPVQ
Sbjct: 347 VPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTSTGLISPGVSVPVQ 406

Query: 421 VPGSEPDMSQYWPRLQ 436
           VPGSEPDMSQYWPRLQ
Sbjct: 407 VPGSEPDMSQYWPRLQ 422


>gi|7524359 paired box 7 isoform 2 [Homo sapiens]
          Length = 518

 Score =  252 bits (644), Expect = 4e-67
 Identities = 179/463 (38%), Positives = 230/463 (49%), Gaps = 95/463 (20%)

Query: 8   VNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNQNVSNGCV 67
           VNQLGGVF+NGRPLP+  R KIVE+AH G RPC ISR L+              VS+GCV
Sbjct: 38  VNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLR--------------VSHGCV 83

Query: 68  SKILGRYYETGSIRPRAIGGSKPR-VATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVC 126
           SKIL RY ETGSIRP AIGGSKPR VATP+V  KI +YKRE P +F+WEIRDRLL +G C
Sbjct: 84  SKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHC 143

Query: 127 TNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQP 186
               +PSVSSI+RVLR    +K++                                    
Sbjct: 144 DRSTVPSVSSISRVLRIKFGKKEE------------------------------------ 167

Query: 187 TQDGCQQQEGGGENTNSISSNG----------EDSD-EAQMRLQLKRKLQRNRTSFTQEQ 235
            +D   ++E  GE     S +G          E SD E++  L LKRK +R+RT+FT EQ
Sbjct: 168 -EDEADKKEDDGEKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQ 226

Query: 236 IEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNT 295
           +E LEK FERTHYPD++ RE LA +  L EAR+QVWFSNRRA+WR++             
Sbjct: 227 LEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLL 286

Query: 296 PSHIPISSSFSTSVYQPIPQPTTPVSSFT--SGSMLGRTD---------------TALTN 338
           P   P +   +   YQ +P  T P ++ +   GS + R                  A  +
Sbjct: 287 PGGFPPTGMPTLPPYQ-LPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAAD 345

Query: 339 TYSALPPMPSFTMANNLPMQPPVPSQTSS--YSCMLPTSPSVNGRSYDTYTPPHMQTHMN 396
           T SA     SF+  ++  M P  PS   +   + + P   S+ G    +  PP  Q   +
Sbjct: 346 TSSAYGARHSFSSYSDSFMNPAAPSNHMNPVSNGLSPQVMSILGN--PSAVPPQPQADFS 403

Query: 397 SQPM--GTSGTTSTGL--------ISPGVSVPVQVPGSEPDMS 429
             P+  G    TS           I PG S+P       P  S
Sbjct: 404 ISPLHGGLDSATSISASCSQRADSIKPGDSLPTSQAYCPPTYS 446


>gi|188219638 paired box 3 isoform PAX3i [Homo sapiens]
          Length = 483

 Score =  250 bits (638), Expect = 2e-66
 Identities = 166/423 (39%), Positives = 227/423 (53%), Gaps = 66/423 (15%)

Query: 8   VNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNQNVSNGCV 67
           VNQLGGVF+NGRPLP+  R KIVE+AH G RPC ISR L+              VS+GCV
Sbjct: 38  VNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLR--------------VSHGCV 83

Query: 68  SKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCT 127
           SKIL RY ETGSIRP AIGGSKP+V TP+V  KI +YKRE P +F+WEIRD+LL + VC 
Sbjct: 84  SKILCRYQETGSIRPGAIGGSKPKVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCD 143

Query: 128 NDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPT 187
            + +PSVSSI+R+LR+   + ++  AD        L  +      +   +   S+ G  +
Sbjct: 144 RNTVPSVSSISRILRSKFGKGEEEEAD--------LERKEAEESEKKAKH---SIDGILS 192

Query: 188 QDGCQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTH 247
           +     Q          S  G D D ++  L LKRK +R+RT+FT EQ+E LE+ FERTH
Sbjct: 193 ERASAPQ----------SDEGSDID-SEPDLPLKRKQRRSRTTFTAEQLEELERAFERTH 241

Query: 248 YPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLR-----NQRRQASNTPSHIPIS 302
           YPD++ RE LA +  L EAR+QVWFSNRRA+WR++         N        P+ +P  
Sbjct: 242 YPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTL 301

Query: 303 SSF--STSVYQP--IPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQ 358
            ++  S + YQP  IPQ  +  SS                 +   P  PS    + +P  
Sbjct: 302 PTYQLSETSYQPTSIPQAVSDPSS---------------TVHRPQPLPPSTVHQSTIPSN 346

Query: 359 PPVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTST-GLISPGVSV 417
           P      SS +  LP++        D++ PP   ++  +  +G   +    GL++    V
Sbjct: 347 P-----DSSSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTNHGGV 401

Query: 418 PVQ 420
           P Q
Sbjct: 402 PHQ 404


>gi|4505619 paired box 7 isoform 1 [Homo sapiens]
          Length = 520

 Score =  247 bits (631), Expect = 1e-65
 Identities = 179/465 (38%), Positives = 230/465 (49%), Gaps = 97/465 (20%)

Query: 8   VNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNQNVSNGCV 67
           VNQLGGVF+NGRPLP+  R KIVE+AH G RPC ISR L+              VS+GCV
Sbjct: 38  VNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLR--------------VSHGCV 83

Query: 68  SKILGRYYETGSIRPRAIGGSKPR-VATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVC 126
           SKIL RY ETGSIRP AIGGSKPR VATP+V  KI +YKRE P +F+WEIRDRLL +G C
Sbjct: 84  SKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHC 143

Query: 127 TNDNIPS--VSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPG 184
               +PS  VSSI+RVLR    +K++                                  
Sbjct: 144 DRSTVPSGLVSSISRVLRIKFGKKEE---------------------------------- 169

Query: 185 QPTQDGCQQQEGGGENTNSISSNG----------EDSD-EAQMRLQLKRKLQRNRTSFTQ 233
              +D   ++E  GE     S +G          E SD E++  L LKRK +R+RT+FT 
Sbjct: 170 ---EDEADKKEDDGEKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTA 226

Query: 234 EQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQAS 293
           EQ+E LEK FERTHYPD++ RE LA +  L EAR+QVWFSNRRA+WR++           
Sbjct: 227 EQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNH 286

Query: 294 NTPSHIPISSSFSTSVYQPIPQPTTPVSSFT--SGSMLGRTD---------------TAL 336
             P   P +   +   YQ +P  T P ++ +   GS + R                  A 
Sbjct: 287 LLPGGFPPTGMPTLPPYQ-LPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAA 345

Query: 337 TNTYSALPPMPSFTMANNLPMQPPVPSQTSS--YSCMLPTSPSVNGRSYDTYTPPHMQTH 394
            +T SA     SF+  ++  M P  PS   +   + + P   S+ G    +  PP  Q  
Sbjct: 346 ADTSSAYGARHSFSSYSDSFMNPAAPSNHMNPVSNGLSPQVMSILGN--PSAVPPQPQAD 403

Query: 395 MNSQPM--GTSGTTSTGL--------ISPGVSVPVQVPGSEPDMS 429
            +  P+  G    TS           I PG S+P       P  S
Sbjct: 404 FSISPLHGGLDSATSISASCSQRADSIKPGDSLPTSQAYCPPTYS 448


>gi|207029223 paired box 7 isoform 3 [Homo sapiens]
          Length = 505

 Score =  247 bits (631), Expect = 1e-65
 Identities = 179/465 (38%), Positives = 230/465 (49%), Gaps = 97/465 (20%)

Query: 8   VNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNQNVSNGCV 67
           VNQLGGVF+NGRPLP+  R KIVE+AH G RPC ISR L+              VS+GCV
Sbjct: 38  VNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLR--------------VSHGCV 83

Query: 68  SKILGRYYETGSIRPRAIGGSKPR-VATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVC 126
           SKIL RY ETGSIRP AIGGSKPR VATP+V  KI +YKRE P +F+WEIRDRLL +G C
Sbjct: 84  SKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHC 143

Query: 127 TNDNIPS--VSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPG 184
               +PS  VSSI+RVLR    +K++                                  
Sbjct: 144 DRSTVPSGLVSSISRVLRIKFGKKEE---------------------------------- 169

Query: 185 QPTQDGCQQQEGGGENTNSISSNG----------EDSD-EAQMRLQLKRKLQRNRTSFTQ 233
              +D   ++E  GE     S +G          E SD E++  L LKRK +R+RT+FT 
Sbjct: 170 ---EDEADKKEDDGEKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTA 226

Query: 234 EQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQAS 293
           EQ+E LEK FERTHYPD++ RE LA +  L EAR+QVWFSNRRA+WR++           
Sbjct: 227 EQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNH 286

Query: 294 NTPSHIPISSSFSTSVYQPIPQPTTPVSSFT--SGSMLGRTD---------------TAL 336
             P   P +   +   YQ +P  T P ++ +   GS + R                  A 
Sbjct: 287 LLPGGFPPTGMPTLPPYQ-LPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAA 345

Query: 337 TNTYSALPPMPSFTMANNLPMQPPVPSQTSS--YSCMLPTSPSVNGRSYDTYTPPHMQTH 394
            +T SA     SF+  ++  M P  PS   +   + + P   S+ G    +  PP  Q  
Sbjct: 346 ADTSSAYGARHSFSSYSDSFMNPAAPSNHMNPVSNGLSPQVMSILGN--PSAVPPQPQAD 403

Query: 395 MNSQPM--GTSGTTSTGL--------ISPGVSVPVQVPGSEPDMS 429
            +  P+  G    TS           I PG S+P       P  S
Sbjct: 404 FSISPLHGGLDSATSISASCSQRADSIKPGDSLPTSQAYCPPTYS 448


>gi|31563344 paired box 3 isoform PAX3e [Homo sapiens]
          Length = 505

 Score =  245 bits (626), Expect = 5e-65
 Identities = 166/424 (39%), Positives = 227/424 (53%), Gaps = 67/424 (15%)

Query: 8   VNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNQNVSNGCV 67
           VNQLGGVF+NGRPLP+  R KIVE+AH G RPC ISR L+              VS+GCV
Sbjct: 38  VNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLR--------------VSHGCV 83

Query: 68  SKILGRYYETGSIRPRAIGGSKPR-VATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVC 126
           SKIL RY ETGSIRP AIGGSKP+ V TP+V  KI +YKRE P +F+WEIRD+LL + VC
Sbjct: 84  SKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVC 143

Query: 127 TNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQP 186
             + +PSVSSI+R+LR+   + ++  AD        L  +      +   +   S+ G  
Sbjct: 144 DRNTVPSVSSISRILRSKFGKGEEEEAD--------LERKEAEESEKKAKH---SIDGIL 192

Query: 187 TQDGCQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERT 246
           ++     Q          S  G D D ++  L LKRK +R+RT+FT EQ+E LE+ FERT
Sbjct: 193 SERASAPQ----------SDEGSDID-SEPDLPLKRKQRRSRTTFTAEQLEELERAFERT 241

Query: 247 HYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLR-----NQRRQASNTPSHIPI 301
           HYPD++ RE LA +  L EAR+QVWFSNRRA+WR++         N        P+ +P 
Sbjct: 242 HYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPT 301

Query: 302 SSSF--STSVYQP--IPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPM 357
             ++  S + YQP  IPQ  +  SS                 +   P  PS    + +P 
Sbjct: 302 LPTYQLSETSYQPTSIPQAVSDPSS---------------TVHRPQPLPPSTVHQSTIPS 346

Query: 358 QPPVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTST-GLISPGVS 416
            P      SS +  LP++        D++ PP   ++  +  +G   +    GL++    
Sbjct: 347 NP-----DSSSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTNHGG 401

Query: 417 VPVQ 420
           VP Q
Sbjct: 402 VPHQ 405


>gi|31563342 paired box 3 isoform PAX3d [Homo sapiens]
          Length = 484

 Score =  245 bits (626), Expect = 5e-65
 Identities = 166/424 (39%), Positives = 227/424 (53%), Gaps = 67/424 (15%)

Query: 8   VNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNQNVSNGCV 67
           VNQLGGVF+NGRPLP+  R KIVE+AH G RPC ISR L+              VS+GCV
Sbjct: 38  VNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLR--------------VSHGCV 83

Query: 68  SKILGRYYETGSIRPRAIGGSKPR-VATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVC 126
           SKIL RY ETGSIRP AIGGSKP+ V TP+V  KI +YKRE P +F+WEIRD+LL + VC
Sbjct: 84  SKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVC 143

Query: 127 TNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQP 186
             + +PSVSSI+R+LR+   + ++  AD        L  +      +   +   S+ G  
Sbjct: 144 DRNTVPSVSSISRILRSKFGKGEEEEAD--------LERKEAEESEKKAKH---SIDGIL 192

Query: 187 TQDGCQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERT 246
           ++     Q          S  G D D ++  L LKRK +R+RT+FT EQ+E LE+ FERT
Sbjct: 193 SERASAPQ----------SDEGSDID-SEPDLPLKRKQRRSRTTFTAEQLEELERAFERT 241

Query: 247 HYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLR-----NQRRQASNTPSHIPI 301
           HYPD++ RE LA +  L EAR+QVWFSNRRA+WR++         N        P+ +P 
Sbjct: 242 HYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPT 301

Query: 302 SSSF--STSVYQP--IPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPM 357
             ++  S + YQP  IPQ  +  SS                 +   P  PS    + +P 
Sbjct: 302 LPTYQLSETSYQPTSIPQAVSDPSS---------------TVHRPQPLPPSTVHQSTIPS 346

Query: 358 QPPVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTST-GLISPGVS 416
            P      SS +  LP++        D++ PP   ++  +  +G   +    GL++    
Sbjct: 347 NP-----DSSSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTNHGG 401

Query: 417 VPVQ 420
           VP Q
Sbjct: 402 VPHQ 405


>gi|31563340 paired box 3 isoform PAX3 [Homo sapiens]
          Length = 479

 Score =  245 bits (626), Expect = 5e-65
 Identities = 166/424 (39%), Positives = 227/424 (53%), Gaps = 67/424 (15%)

Query: 8   VNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNQNVSNGCV 67
           VNQLGGVF+NGRPLP+  R KIVE+AH G RPC ISR L+              VS+GCV
Sbjct: 38  VNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLR--------------VSHGCV 83

Query: 68  SKILGRYYETGSIRPRAIGGSKPR-VATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVC 126
           SKIL RY ETGSIRP AIGGSKP+ V TP+V  KI +YKRE P +F+WEIRD+LL + VC
Sbjct: 84  SKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVC 143

Query: 127 TNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQP 186
             + +PSVSSI+R+LR+   + ++  AD        L  +      +   +   S+ G  
Sbjct: 144 DRNTVPSVSSISRILRSKFGKGEEEEAD--------LERKEAEESEKKAKH---SIDGIL 192

Query: 187 TQDGCQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERT 246
           ++     Q          S  G D D ++  L LKRK +R+RT+FT EQ+E LE+ FERT
Sbjct: 193 SERASAPQ----------SDEGSDID-SEPDLPLKRKQRRSRTTFTAEQLEELERAFERT 241

Query: 247 HYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLR-----NQRRQASNTPSHIPI 301
           HYPD++ RE LA +  L EAR+QVWFSNRRA+WR++         N        P+ +P 
Sbjct: 242 HYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPT 301

Query: 302 SSSF--STSVYQP--IPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPM 357
             ++  S + YQP  IPQ  +  SS                 +   P  PS    + +P 
Sbjct: 302 LPTYQLSETSYQPTSIPQAVSDPSS---------------TVHRPQPLPPSTVHQSTIPS 346

Query: 358 QPPVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTST-GLISPGVS 416
            P      SS +  LP++        D++ PP   ++  +  +G   +    GL++    
Sbjct: 347 NP-----DSSSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTNHGG 401

Query: 417 VPVQ 420
           VP Q
Sbjct: 402 VPHQ 405


>gi|31563348 paired box 3 isoform PAX3g [Homo sapiens]
          Length = 403

 Score =  244 bits (624), Expect = 9e-65
 Identities = 160/392 (40%), Positives = 214/392 (54%), Gaps = 66/392 (16%)

Query: 8   VNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNQNVSNGCV 67
           VNQLGGVF+NGRPLP+  R KIVE+AH G RPC ISR L+              VS+GCV
Sbjct: 38  VNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLR--------------VSHGCV 83

Query: 68  SKILGRYYETGSIRPRAIGGSKPR-VATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVC 126
           SKIL RY ETGSIRP AIGGSKP+ V TP+V  KI +YKRE P +F+WEIRD+LL + VC
Sbjct: 84  SKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVC 143

Query: 127 TNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQP 186
             + +PSVSSI+R+LR+   + ++  AD        L  +      +   +   S+ G  
Sbjct: 144 DRNTVPSVSSISRILRSKFGKGEEEEAD--------LERKEAEESEKKAKH---SIDGIL 192

Query: 187 TQDGCQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERT 246
           ++     Q          S  G D D ++  L LKRK +R+RT+FT EQ+E LE+ FERT
Sbjct: 193 SERASAPQ----------SDEGSDID-SEPDLPLKRKQRRSRTTFTAEQLEELERAFERT 241

Query: 247 HYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLR-----NQRRQASNTPSHIPI 301
           HYPD++ RE LA +  L EAR+QVWFSNRRA+WR++         N        P+ +P 
Sbjct: 242 HYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPT 301

Query: 302 SSSF--STSVYQP--IPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPM 357
             ++  S + YQP  IPQ  +  SS                 +   P  PS    + +P 
Sbjct: 302 LPTYQLSETSYQPTSIPQAVSDPSS---------------TVHRPQPLPPSTVHQSTIPS 346

Query: 358 QPPVPSQTSSYSCMLPTSPSVNGRSYDTYTPP 389
            P      SS +  LP++        D++ PP
Sbjct: 347 NP-----DSSSAYCLPSTRHGFSSYTDSFVPP 373


>gi|31563346 paired box 3 isoform PAX3h [Homo sapiens]
          Length = 407

 Score =  244 bits (624), Expect = 9e-65
 Identities = 160/392 (40%), Positives = 214/392 (54%), Gaps = 66/392 (16%)

Query: 8   VNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNQNVSNGCV 67
           VNQLGGVF+NGRPLP+  R KIVE+AH G RPC ISR L+              VS+GCV
Sbjct: 38  VNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLR--------------VSHGCV 83

Query: 68  SKILGRYYETGSIRPRAIGGSKPR-VATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVC 126
           SKIL RY ETGSIRP AIGGSKP+ V TP+V  KI +YKRE P +F+WEIRD+LL + VC
Sbjct: 84  SKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVC 143

Query: 127 TNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQP 186
             + +PSVSSI+R+LR+   + ++  AD        L  +      +   +   S+ G  
Sbjct: 144 DRNTVPSVSSISRILRSKFGKGEEEEAD--------LERKEAEESEKKAKH---SIDGIL 192

Query: 187 TQDGCQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERT 246
           ++     Q          S  G D D ++  L LKRK +R+RT+FT EQ+E LE+ FERT
Sbjct: 193 SERASAPQ----------SDEGSDID-SEPDLPLKRKQRRSRTTFTAEQLEELERAFERT 241

Query: 247 HYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLR-----NQRRQASNTPSHIPI 301
           HYPD++ RE LA +  L EAR+QVWFSNRRA+WR++         N        P+ +P 
Sbjct: 242 HYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPT 301

Query: 302 SSSF--STSVYQP--IPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPM 357
             ++  S + YQP  IPQ  +  SS                 +   P  PS    + +P 
Sbjct: 302 LPTYQLSETSYQPTSIPQAVSDPSS---------------TVHRPQPLPPSTVHQSTIPS 346

Query: 358 QPPVPSQTSSYSCMLPTSPSVNGRSYDTYTPP 389
            P      SS +  LP++        D++ PP
Sbjct: 347 NP-----DSSSAYCLPSTRHGFSSYTDSFVPP 373


>gi|170784824 paired box 4 [Homo sapiens]
          Length = 343

 Score =  235 bits (599), Expect = 7e-62
 Identities = 139/283 (49%), Positives = 166/283 (58%), Gaps = 63/283 (22%)

Query: 8   VNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNQNVSNGCV 67
           +NQLGG+FVNGRPLP  TRQ+IV LA SG RPCDISRIL+              VSNGCV
Sbjct: 1   MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILK--------------VSNGCV 46

Query: 68  SKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCT 127
           SKILGRYY TG + P+ IGGSKPR+ATP VV++IAQ K ECP++FAWEI+ +L +EG+CT
Sbjct: 47  SKILGRYYRTGVLEPKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCT 106

Query: 128 NDNIPSVSSINRVLRNLASEKQQMGADGMYDKL----RMLNGQTGSWGTRPGWYPGTSVP 183
            D  PSVSSINRVLR L  E Q +    +         +L   +GS  T  G +PGT   
Sbjct: 107 QDKTPSVSSINRVLRAL-QEDQGLPCTRLRSPAVLAPAVLTPHSGS-ETPRGTHPGTG-- 162

Query: 184 GQPTQDGCQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEF 243
                                                     RNRT F+  Q EALEKEF
Sbjct: 163 -----------------------------------------HRNRTIFSPSQAEALEKEF 181

Query: 244 ERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLR 286
           +R  YPD  AR +LA    LPE  ++VWFSNRRAKWRR+EKL+
Sbjct: 182 QRGQYPDSVARGKLATATSLPEDTVRVWFSNRRAKWRRQEKLK 224


>gi|34878709 paired box protein 2 isoform c [Homo sapiens]
          Length = 396

 Score =  230 bits (586), Expect = 2e-60
 Identities = 165/415 (39%), Positives = 211/415 (50%), Gaps = 56/415 (13%)

Query: 1   MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNQ 60
           M   H GVNQLGGVFVNGRPLPD  RQ+IVELAH G RPCDISR L+             
Sbjct: 13  MHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLR------------- 59

Query: 61  NVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRL 120
            VS+GCVSKILGRYYETGSI+P  IGGSKP+VATP+VV KIA+YKR+ P++FAWEIRDRL
Sbjct: 60  -VSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRL 118

Query: 121 LSEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGT 180
           L+EG+C ND +PSVSSINR++R    +      DG            G+  T PG    T
Sbjct: 119 LAEGICDNDTVPSVSSINRIIRTKVQQPFHPTPDG-----------AGTGVTAPG---HT 164

Query: 181 SVP--GQPTQDGCQQQEGGGENTNSI----SSNGE----DSD---------EAQMRLQLK 221
            VP    P          G  + N I     SNGE    D D         ++Q  +   
Sbjct: 165 IVPSTASPPVSSASNDPVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSL 224

Query: 222 RKLQRNRTSFTQEQIEALEKEFERTHYPDVF-ARERLAA----KIDLPEARIQVWFSNRR 276
           RK  R  T FTQ+Q+EAL++ FER  YPDVF A E + +    +  LP     +      
Sbjct: 225 RKHLRADT-FTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSS 283

Query: 277 AKWRREEKLRNQRRQASNTPSHIPISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTAL 336
                  +L +        P       + +T    P   P T   S+ + ++ G    A 
Sbjct: 284 LSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPEAA 343

Query: 337 TNTYSALPPMPSFTMANNLP-MQPPVPSQTSSYSCMLPTSPSVNGRSYDTYTPPH 390
               S+L   P   +A   P +QP   S  ++ +    T P+   R  D+ TPP+
Sbjct: 344 VGPSSSLMSKPGRKLAEVPPCVQPTGASSPATRTATPSTRPTT--RLGDSATPPY 396


>gi|34878716 paired box protein 2 isoform d [Homo sapiens]
          Length = 408

 Score =  226 bits (575), Expect = 4e-59
 Identities = 137/271 (50%), Positives = 162/271 (59%), Gaps = 48/271 (17%)

Query: 1   MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNQ 60
           M   H GVNQLGGVFVNGRPLPD  RQ+IVELAH G RPCDISR L+             
Sbjct: 13  MHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLR------------- 59

Query: 61  NVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRL 120
            VS+GCVSKILGRYYETGSI+P  IGGSKP+VATP+VV KIA+YKR+ P++FAWEIRDRL
Sbjct: 60  -VSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRL 118

Query: 121 LSEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGT 180
           L+EG+C ND +PSVSSINR++R    +      DG            G+  T PG    T
Sbjct: 119 LAEGICDNDTVPSVSSINRIIRTKVQQPFHPTPDG-----------AGTGVTAPG---HT 164

Query: 181 SVP--GQPTQDGCQQQEGGGENTNSI----SSNGE----DSD---------EAQMRLQLK 221
            VP    P          G  + N I     SNGE    D D         ++Q  +   
Sbjct: 165 IVPSTASPPVSSASNDPVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSL 224

Query: 222 RKLQRNRTSFTQEQIEALEKEFERTHYPDVF 252
           RK  R  T FTQ+Q+EAL++ FER  YPDVF
Sbjct: 225 RKHLRADT-FTQQQLEALDRVFERPSYPDVF 254


>gi|34878701 paired box protein 2 isoform b [Homo sapiens]
          Length = 393

 Score =  226 bits (575), Expect = 4e-59
 Identities = 137/271 (50%), Positives = 162/271 (59%), Gaps = 48/271 (17%)

Query: 1   MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNQ 60
           M   H GVNQLGGVFVNGRPLPD  RQ+IVELAH G RPCDISR L+             
Sbjct: 13  MHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLR------------- 59

Query: 61  NVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRL 120
            VS+GCVSKILGRYYETGSI+P  IGGSKP+VATP+VV KIA+YKR+ P++FAWEIRDRL
Sbjct: 60  -VSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRL 118

Query: 121 LSEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGT 180
           L+EG+C ND +PSVSSINR++R    +      DG            G+  T PG    T
Sbjct: 119 LAEGICDNDTVPSVSSINRIIRTKVQQPFHPTPDG-----------AGTGVTAPG---HT 164

Query: 181 SVP--GQPTQDGCQQQEGGGENTNSI----SSNGE----DSD---------EAQMRLQLK 221
            VP    P          G  + N I     SNGE    D D         ++Q  +   
Sbjct: 165 IVPSTASPPVSSASNDPVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSL 224

Query: 222 RKLQRNRTSFTQEQIEALEKEFERTHYPDVF 252
           RK  R  T FTQ+Q+EAL++ FER  YPDVF
Sbjct: 225 RKHLRADT-FTQQQLEALDRVFERPSYPDVF 254


>gi|34878699 paired box protein 2 isoform a [Homo sapiens]
          Length = 416

 Score =  220 bits (560), Expect = 2e-57
 Identities = 134/291 (46%), Positives = 165/291 (56%), Gaps = 65/291 (22%)

Query: 1   MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNQ 60
           M   H GVNQLGGVFVNGRPLPD  RQ+IVELAH G RPCDISR L+             
Sbjct: 13  MHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLR------------- 59

Query: 61  NVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRL 120
            VS+GCVSKILGRYYETGSI+P  IGGSKP+VATP+VV KIA+YKR+ P++FAWEIRDRL
Sbjct: 60  -VSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRL 118

Query: 121 LSEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGW--YP 178
           L+EG+C ND +PSVSSINR++R    +      DG            G+  T PG    P
Sbjct: 119 LAEGICDNDTVPSVSSINRIIRTKVQQPFHPTPDG-----------AGTGVTAPGHTIVP 167

Query: 179 GTSVP-------------------GQPTQDGCQQQ-------------EGGGE-----NT 201
            T+ P                   G P  +G +++              GGG        
Sbjct: 168 STASPPVSSASNDPVGSYSINGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTL 227

Query: 202 NSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVF 252
             +S     + ++Q  +   RK  R  T FTQ+Q+EAL++ FER  YPDVF
Sbjct: 228 RDVSEGSVPNGDSQSGVDSLRKHLRADT-FTQQQLEALDRVFERPSYPDVF 277


>gi|34878703 paired box protein 2 isoform e [Homo sapiens]
          Length = 431

 Score =  220 bits (560), Expect = 2e-57
 Identities = 134/291 (46%), Positives = 165/291 (56%), Gaps = 65/291 (22%)

Query: 1   MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNQ 60
           M   H GVNQLGGVFVNGRPLPD  RQ+IVELAH G RPCDISR L+             
Sbjct: 13  MHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLR------------- 59

Query: 61  NVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRL 120
            VS+GCVSKILGRYYETGSI+P  IGGSKP+VATP+VV KIA+YKR+ P++FAWEIRDRL
Sbjct: 60  -VSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRL 118

Query: 121 LSEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGW--YP 178
           L+EG+C ND +PSVSSINR++R    +      DG            G+  T PG    P
Sbjct: 119 LAEGICDNDTVPSVSSINRIIRTKVQQPFHPTPDG-----------AGTGVTAPGHTIVP 167

Query: 179 GTSVP-------------------GQPTQDGCQQQ-------------EGGGE-----NT 201
            T+ P                   G P  +G +++              GGG        
Sbjct: 168 STASPPVSSASNDPVGSYSINGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTL 227

Query: 202 NSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVF 252
             +S     + ++Q  +   RK  R  T FTQ+Q+EAL++ FER  YPDVF
Sbjct: 228 RDVSEGSVPNGDSQSGVDSLRKHLRADT-FTQQQLEALDRVFERPSYPDVF 277


>gi|5803117 paired box 8 isoform PAX8A [Homo sapiens]
          Length = 450

 Score =  217 bits (553), Expect = 1e-56
 Identities = 154/425 (36%), Positives = 206/425 (48%), Gaps = 82/425 (19%)

Query: 1   MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNQ 60
           +++ H G+NQLGG FVNGRPLP+  RQ+IV+LAH G RPCDISR L+             
Sbjct: 6   IRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLR------------- 52

Query: 61  NVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRL 120
            VS+GCVSKILGRYYETGSIRP  IGGSKP+VATP+VV KI  YKR+ P++FAWEIRDRL
Sbjct: 53  -VSHGCVSKILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRL 111

Query: 121 LSEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGT 180
           L+EGVC ND +PSVSSINR++R    +   +  D       +  G T          P +
Sbjct: 112 LAEGVCDNDTVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHT--------LIPSS 163

Query: 181 SV--PGQPTQDGCQQQEG-----GGENTNSISSNGEDSDEAQMRLQLKRKLQRN------ 227
           +V  P  P  D            G     S     +DSD+   RL +  +   +      
Sbjct: 164 AVTPPESPQSDSLGSTYSINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHL 223

Query: 228 RT-SFTQEQIEALEKEFERTHYPDVFAR------ERLAAKIDLPEARIQVWFSNRRAKWR 280
           RT +F+Q  +E LE  FER HYP+ +A       E+    + L  + +            
Sbjct: 224 RTDAFSQHHLEPLECPFERQHYPEAYASPSHTKGEQGLYPLPLLNSTL------------ 271

Query: 281 REEKLRNQRRQASNTPSHIPISSSFST-SVYQPIPQPTTPV-----------SSFTSGSM 328
                     +A+ TPS+ P+  + ST   Y  +  P +P            SS T  S+
Sbjct: 272 -------DDGKATLTPSNTPLGRNLSTHQTYPVVADPHSPFAIKQETPEVSSSSSTPSSL 324

Query: 329 LGRTDTALTNTYSALPPMPSFTMANNLPMQPPVPSQTSSYSCMLPTSPSVNGRSYDTYTP 388
                  L    S +PP  +F  A ++  Q    +  S    + PT P           P
Sbjct: 325 SSSAFLDLQQVGSGVPPFNAFPHAASVYGQFTGQALLSGREMVGPTLPGY---------P 375

Query: 389 PHMQT 393
           PH+ T
Sbjct: 376 PHIPT 380


>gi|9951920 paired box 5 [Homo sapiens]
          Length = 391

 Score =  215 bits (548), Expect = 6e-56
 Identities = 125/262 (47%), Positives = 158/262 (60%), Gaps = 36/262 (13%)

Query: 2   QNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNQN 61
           +  H GVNQLGGVFVNGRPLPD  RQ+IVELAH G RPCDISR L+              
Sbjct: 14  RTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLR-------------- 59

Query: 62  VSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLL 121
           VS+GCVSKILGRYYETGSI+P  IGGSKP+VATP+VV KIA+YKR+ P++FAWEIRDRLL
Sbjct: 60  VSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLL 119

Query: 122 SEGVCTNDNIPSVSSINRVLRN---------LASEKQQMGADGMYDKLRMLNGQTGSWGT 172
           +E VC ND +PSVSSINR++R          + +    + + G   ++  ++  +     
Sbjct: 120 AERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSY 179

Query: 173 RPGWYPGTSVPGQPTQDGCQQQEGGGEN--TNSISSNGEDSDEAQMRLQLKRKLQRNRTS 230
                 G + P   T    ++ EG  E+   N  S  G D    QMR  L          
Sbjct: 180 SISGILGITSPSADTNKR-KRDEGIQESPVPNGHSLPGRDFLRKQMRGDL---------- 228

Query: 231 FTQEQIEALEKEFERTHYPDVF 252
           FTQ+Q+E L++ FER HY D+F
Sbjct: 229 FTQQQLEVLDRVFERQHYSDIF 250


>gi|7524365 paired box 8 isoform PAX8D [Homo sapiens]
          Length = 321

 Score =  213 bits (541), Expect = 4e-55
 Identities = 123/267 (46%), Positives = 156/267 (58%), Gaps = 36/267 (13%)

Query: 1   MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNQ 60
           +++ H G+NQLGG FVNGRPLP+  RQ+IV+LAH G RPCDISR L+             
Sbjct: 6   IRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLR------------- 52

Query: 61  NVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRL 120
            VS+GCVSKILGRYYETGSIRP  IGGSKP+VATP+VV KI  YKR+ P++FAWEIRDRL
Sbjct: 53  -VSHGCVSKILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRL 111

Query: 121 LSEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGT 180
           L+EGVC ND +PSVSSINR++R    +   +  D       +  G T          P +
Sbjct: 112 LAEGVCDNDTVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHT--------LIPSS 163

Query: 181 SV--PGQPTQDGCQQQEG-----GGENTNSISSNGEDSDEAQMRLQLKRKLQRN------ 227
           +V  P  P  D            G     S     +DSD+   RL +  +   +      
Sbjct: 164 AVTPPESPQSDSLGSTYSINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHL 223

Query: 228 RT-SFTQEQIEALEKEFERTHYPDVFA 253
           RT +F+Q  +E LE  FER HYP+ +A
Sbjct: 224 RTDAFSQHHLEPLECPFERQHYPEAYA 250


>gi|7669542 paired box 8 isoform PAX8E [Homo sapiens]
          Length = 287

 Score =  213 bits (541), Expect = 4e-55
 Identities = 123/267 (46%), Positives = 156/267 (58%), Gaps = 36/267 (13%)

Query: 1   MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNQ 60
           +++ H G+NQLGG FVNGRPLP+  RQ+IV+LAH G RPCDISR L+             
Sbjct: 6   IRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLR------------- 52

Query: 61  NVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRL 120
            VS+GCVSKILGRYYETGSIRP  IGGSKP+VATP+VV KI  YKR+ P++FAWEIRDRL
Sbjct: 53  -VSHGCVSKILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRL 111

Query: 121 LSEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGT 180
           L+EGVC ND +PSVSSINR++R    +   +  D       +  G T          P +
Sbjct: 112 LAEGVCDNDTVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHT--------LIPSS 163

Query: 181 SV--PGQPTQDGCQQQEG-----GGENTNSISSNGEDSDEAQMRLQLKRKLQRN------ 227
           +V  P  P  D            G     S     +DSD+   RL +  +   +      
Sbjct: 164 AVTPPESPQSDSLGSTYSINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHL 223

Query: 228 RT-SFTQEQIEALEKEFERTHYPDVFA 253
           RT +F+Q  +E LE  FER HYP+ +A
Sbjct: 224 RTDAFSQHHLEPLECPFERQHYPEAYA 250


>gi|7524363 paired box 8 isoform PAX8C [Homo sapiens]
          Length = 398

 Score =  213 bits (541), Expect = 4e-55
 Identities = 123/267 (46%), Positives = 156/267 (58%), Gaps = 36/267 (13%)

Query: 1   MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNQ 60
           +++ H G+NQLGG FVNGRPLP+  RQ+IV+LAH G RPCDISR L+             
Sbjct: 6   IRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLR------------- 52

Query: 61  NVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRL 120
            VS+GCVSKILGRYYETGSIRP  IGGSKP+VATP+VV KI  YKR+ P++FAWEIRDRL
Sbjct: 53  -VSHGCVSKILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRL 111

Query: 121 LSEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGT 180
           L+EGVC ND +PSVSSINR++R    +   +  D       +  G T          P +
Sbjct: 112 LAEGVCDNDTVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHT--------LIPSS 163

Query: 181 SV--PGQPTQDGCQQQEG-----GGENTNSISSNGEDSDEAQMRLQLKRKLQRN------ 227
           +V  P  P  D            G     S     +DSD+   RL +  +   +      
Sbjct: 164 AVTPPESPQSDSLGSTYSINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHL 223

Query: 228 RT-SFTQEQIEALEKEFERTHYPDVFA 253
           RT +F+Q  +E LE  FER HYP+ +A
Sbjct: 224 RTDAFSQHHLEPLECPFERQHYPEAYA 250


>gi|7524361 paired box 8 isoform PAX8B [Homo sapiens]
          Length = 387

 Score =  213 bits (541), Expect = 4e-55
 Identities = 123/267 (46%), Positives = 156/267 (58%), Gaps = 36/267 (13%)

Query: 1   MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNQ 60
           +++ H G+NQLGG FVNGRPLP+  RQ+IV+LAH G RPCDISR L+             
Sbjct: 6   IRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLR------------- 52

Query: 61  NVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRL 120
            VS+GCVSKILGRYYETGSIRP  IGGSKP+VATP+VV KI  YKR+ P++FAWEIRDRL
Sbjct: 53  -VSHGCVSKILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRL 111

Query: 121 LSEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGT 180
           L+EGVC ND +PSVSSINR++R    +   +  D       +  G T          P +
Sbjct: 112 LAEGVCDNDTVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHT--------LIPSS 163

Query: 181 SV--PGQPTQDGCQQQEG-----GGENTNSISSNGEDSDEAQMRLQLKRKLQRN------ 227
           +V  P  P  D            G     S     +DSD+   RL +  +   +      
Sbjct: 164 AVTPPESPQSDSLGSTYSINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHL 223

Query: 228 RT-SFTQEQIEALEKEFERTHYPDVFA 253
           RT +F+Q  +E LE  FER HYP+ +A
Sbjct: 224 RTDAFSQHHLEPLECPFERQHYPEAYA 250


>gi|197276661 paired box 1 [Homo sapiens]
          Length = 534

 Score =  173 bits (438), Expect = 3e-43
 Identities = 92/152 (60%), Positives = 106/152 (69%), Gaps = 14/152 (9%)

Query: 1   MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNQ 60
           M+ ++  VNQLGGVFVNGRPLP++ R +IVELA  G RPCDISR L+             
Sbjct: 95  MEQTYGEVNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLR------------- 141

Query: 61  NVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRL 120
            VS+GCVSKIL RY ETGSI P AIGGSKPRV TP VV  I  YK+  P IFAWEIRDRL
Sbjct: 142 -VSHGCVSKILARYNETGSILPGAIGGSKPRVTTPNVVKHIRDYKQGDPGIFAWEIRDRL 200

Query: 121 LSEGVCTNDNIPSVSSINRVLRNLASEKQQMG 152
           L++GVC   N+PSVSSI+R+LRN      Q G
Sbjct: 201 LADGVCDKYNVPSVSSISRILRNKIGSLAQPG 232


>gi|7242167 paired box 9 [Homo sapiens]
          Length = 341

 Score =  172 bits (435), Expect = 7e-43
 Identities = 92/152 (60%), Positives = 105/152 (69%), Gaps = 14/152 (9%)

Query: 1   MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNQ 60
           M+ +   VNQLGGVFVNGRPLP++ R +IVELA  G RPCDISR L+             
Sbjct: 1   MEPAFGEVNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLR------------- 47

Query: 61  NVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRL 120
            VS+GCVSKIL RY ETGSI P AIGGSKPRV TP VV  I  YK+  P IFAWEIRDRL
Sbjct: 48  -VSHGCVSKILARYNETGSILPGAIGGSKPRVTTPTVVKHIRTYKQRDPGIFAWEIRDRL 106

Query: 121 LSEGVCTNDNIPSVSSINRVLRNLASEKQQMG 152
           L++GVC   N+PSVSSI+R+LRN      Q G
Sbjct: 107 LADGVCDKYNVPSVSSISRILRNKIGNLAQQG 138


>gi|7524356 paired box 3 isoform PAX3b [Homo sapiens]
          Length = 206

 Score =  164 bits (414), Expect = 2e-40
 Identities = 86/148 (58%), Positives = 106/148 (71%), Gaps = 15/148 (10%)

Query: 8   VNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNQNVSNGCV 67
           VNQLGGVF+NGRPLP+  R KIVE+AH G RPC ISR L+              VS+GCV
Sbjct: 38  VNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLR--------------VSHGCV 83

Query: 68  SKILGRYYETGSIRPRAIGGSKPR-VATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVC 126
           SKIL RY ETGSIRP AIGGSKP+ V TP+V  KI +YKRE P +F+WEIRD+LL + VC
Sbjct: 84  SKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVC 143

Query: 127 TNDNIPSVSSINRVLRNLASEKQQMGAD 154
             + +PSVSSI+R+LR+   + ++  AD
Sbjct: 144 DRNTVPSVSSISRILRSKFGKGEEEEAD 171


>gi|6654638 paired box 3 isoform PAX3a [Homo sapiens]
          Length = 215

 Score =  164 bits (414), Expect = 2e-40
 Identities = 86/148 (58%), Positives = 106/148 (71%), Gaps = 15/148 (10%)

Query: 8   VNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNQNVSNGCV 67
           VNQLGGVF+NGRPLP+  R KIVE+AH G RPC ISR L+              VS+GCV
Sbjct: 38  VNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLR--------------VSHGCV 83

Query: 68  SKILGRYYETGSIRPRAIGGSKPR-VATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVC 126
           SKIL RY ETGSIRP AIGGSKP+ V TP+V  KI +YKRE P +F+WEIRD+LL + VC
Sbjct: 84  SKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVC 143

Query: 127 TNDNIPSVSSINRVLRNLASEKQQMGAD 154
             + +PSVSSI+R+LR+   + ++  AD
Sbjct: 144 DRNTVPSVSSISRILRSKFGKGEEEEAD 171


>gi|126116581 retina and anterior neural fold homeobox [Homo
           sapiens]
          Length = 346

 Score =  109 bits (273), Expect = 4e-24
 Identities = 69/164 (42%), Positives = 90/164 (54%), Gaps = 12/164 (7%)

Query: 219 QLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAK 278
           Q K+K +RNRT+FT  Q+  LE+ FE++HYPDV++RE LA K++LPE R+QVWF NRRAK
Sbjct: 131 QPKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAGKVNLPEVRVQVWFQNRRAK 190

Query: 279 WRREEKLRNQRRQASNTPSHIPISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTN 338
           WRR+EKL     +  ++P       SFS S     P  T        GS  G    AL  
Sbjct: 191 WRRQEKLEVSSMKLQDSP-----LLSFSRSP----PSATLSPLGAGPGSGGGPAGGALPL 241

Query: 339 TYSALPPMP--SFTMANNLP-MQPPVPSQTSSYSCMLPTSPSVN 379
                PP+P    T   +LP   PP  S  +SY+   P  P +N
Sbjct: 242 ESWLGPPLPGGGATALQSLPGFGPPAQSLPASYTPPPPPPPFLN 285


>gi|12707577 paired mesoderm homeobox 1 isoform pmx-1b [Homo
           sapiens]
          Length = 245

 Score =  108 bits (270), Expect = 1e-23
 Identities = 66/159 (41%), Positives = 91/159 (57%), Gaps = 14/159 (8%)

Query: 201 TNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAK 260
           T+   +  +D+D+     + KRK +RNRT+F   Q++ALE+ FERTHYPD F RE LA +
Sbjct: 71  TSGSDTPQQDNDQLNSEEKKKRKQRRNRTTFNSSQLQALERVFERTHYPDAFVREDLARR 130

Query: 261 IDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSFSTSVYQPI-PQPTTP 319
           ++L EAR+QVWF NRRAK+RR E+     + AS   S+    S   T+V QPI P+P   
Sbjct: 131 VNLTEARVQVWFQNRRAKFRRNERAMLANKNASLLKSY----SGDVTAVEQPIVPRPAPR 186

Query: 320 VSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQ 358
            + + S            + YSA+    S T ANN P Q
Sbjct: 187 PTDYLS--------WGTASPYSAMATY-SATCANNSPAQ 216


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.128    0.381 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,885,222
Number of Sequences: 37866
Number of extensions: 966837
Number of successful extensions: 4673
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 308
Number of HSP's successfully gapped in prelim test: 226
Number of HSP's that attempted gapping in prelim test: 3625
Number of HSP's gapped (non-prelim): 1068
length of query: 436
length of database: 18,247,518
effective HSP length: 105
effective length of query: 331
effective length of database: 14,271,588
effective search space: 4723895628
effective search space used: 4723895628
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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