Search of human proteins with 45643127

Search of human proteins with 45643127

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|45643127 guanine nucleotide binding protein-like 3 isoform 2
[Homo sapiens]
         (537 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|45643129 guanine nucleotide binding protein-like 3 isoform 2 ...  1066   0.0  
gi|45643127 guanine nucleotide binding protein-like 3 isoform 2 ...  1066   0.0  
gi|45593130 guanine nucleotide binding protein-like 3 isoform 1 ...  1066   0.0  
gi|9506611 guanine nucleotide binding protein-like 3 (nucleolar)...   282   6e-76
gi|7019419 guanine nucleotide binding protein-like 2 (nucleolar)...   171   1e-42
gi|93277113 GTP_binding protein [Homo sapiens]                         61   2e-09
gi|223029424 large subunit GTPase 1 [Homo sapiens]                     59   1e-08
gi|38788319 guanine nucleotide binding protein-like 1 [Homo sapi...    51   3e-06
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]            44   5e-04
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     44   5e-04
gi|221219020 NYD-SP11 protein [Homo sapiens]                           42   0.001
gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]    42   0.001
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]            42   0.001
gi|148746195 trichohyalin [Homo sapiens]                               42   0.001
gi|4503179 oral-facial-digital syndrome 1 [Homo sapiens]               41   0.002
gi|153945728 microtubule-associated protein 1B [Homo sapiens]          41   0.003
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    41   0.003
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa...    40   0.004
gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens]    40   0.005
gi|88759339 aster-associated protein [Homo sapiens]                    40   0.005
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa...    40   0.007
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]                       39   0.009
gi|94680976 coiled-coil domain containing 112 isoform 1 [Homo sa...    39   0.012
gi|145580595 coiled-coil domain containing 112 isoform 2 [Homo s...    39   0.012
gi|24308223 hypothetical protein LOC57577 [Homo sapiens]               39   0.012
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik...    39   0.016
gi|154354979 myosin X [Homo sapiens]                                   39   0.016
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]             39   0.016
gi|16262452 cingulin [Homo sapiens]                                    38   0.020
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]     38   0.020

>gi|45643129 guanine nucleotide binding protein-like 3 isoform 2
           [Homo sapiens]
          Length = 537

 Score = 1066 bits (2756), Expect = 0.0
 Identities = 537/537 (100%), Positives = 537/537 (100%)

Query: 1   MTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLE 60
           MTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLE
Sbjct: 1   MTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLE 60

Query: 61  ELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQ 120
           ELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQ
Sbjct: 61  ELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQ 120

Query: 121 ELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLILNKSDLVPKENLESWL 180
           ELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLILNKSDLVPKENLESWL
Sbjct: 121 ELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLILNKSDLVPKENLESWL 180

Query: 181 NYLKKELPTVVFRASTKPKDKGKITKRVKAKKNAAPFRSEVCFGKEGLWKLLGGFQETCS 240
           NYLKKELPTVVFRASTKPKDKGKITKRVKAKKNAAPFRSEVCFGKEGLWKLLGGFQETCS
Sbjct: 181 NYLKKELPTVVFRASTKPKDKGKITKRVKAKKNAAPFRSEVCFGKEGLWKLLGGFQETCS 240

Query: 241 KAIRVGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSMQVVPLDKQITIIDSPSFIVS 300
           KAIRVGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSMQVVPLDKQITIIDSPSFIVS
Sbjct: 241 KAIRVGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSMQVVPLDKQITIIDSPSFIVS 300

Query: 301 PLNSSSALALRSPASIEVVKPMEAASAILSQADARQVVLKYTVPGYRNSLEFFTVLAQRR 360
           PLNSSSALALRSPASIEVVKPMEAASAILSQADARQVVLKYTVPGYRNSLEFFTVLAQRR
Sbjct: 301 PLNSSSALALRSPASIEVVKPMEAASAILSQADARQVVLKYTVPGYRNSLEFFTVLAQRR 360

Query: 361 GMHQKGGIPNVEGAAKLLWSEWTGASLAYYCHPPTSWTPPPYFNESIVVDMKSGFNLEEL 420
           GMHQKGGIPNVEGAAKLLWSEWTGASLAYYCHPPTSWTPPPYFNESIVVDMKSGFNLEEL
Sbjct: 361 GMHQKGGIPNVEGAAKLLWSEWTGASLAYYCHPPTSWTPPPYFNESIVVDMKSGFNLEEL 420

Query: 421 EKNNAQSIRAIKGPHLANSILFQSSGLTNGIIEEKDIHEELPKRKERKQEEREDDKDSDQ 480
           EKNNAQSIRAIKGPHLANSILFQSSGLTNGIIEEKDIHEELPKRKERKQEEREDDKDSDQ
Sbjct: 421 EKNNAQSIRAIKGPHLANSILFQSSGLTNGIIEEKDIHEELPKRKERKQEEREDDKDSDQ 480

Query: 481 ETVDEEVDENSSGMFAAEETGEALSEETTAGEQSTRSFILDKIIEEDDAYDFSTDYV 537
           ETVDEEVDENSSGMFAAEETGEALSEETTAGEQSTRSFILDKIIEEDDAYDFSTDYV
Sbjct: 481 ETVDEEVDENSSGMFAAEETGEALSEETTAGEQSTRSFILDKIIEEDDAYDFSTDYV 537


>gi|45643127 guanine nucleotide binding protein-like 3 isoform 2
           [Homo sapiens]
          Length = 537

 Score = 1066 bits (2756), Expect = 0.0
 Identities = 537/537 (100%), Positives = 537/537 (100%)

Query: 1   MTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLE 60
           MTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLE
Sbjct: 1   MTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLE 60

Query: 61  ELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQ 120
           ELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQ
Sbjct: 61  ELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQ 120

Query: 121 ELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLILNKSDLVPKENLESWL 180
           ELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLILNKSDLVPKENLESWL
Sbjct: 121 ELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLILNKSDLVPKENLESWL 180

Query: 181 NYLKKELPTVVFRASTKPKDKGKITKRVKAKKNAAPFRSEVCFGKEGLWKLLGGFQETCS 240
           NYLKKELPTVVFRASTKPKDKGKITKRVKAKKNAAPFRSEVCFGKEGLWKLLGGFQETCS
Sbjct: 181 NYLKKELPTVVFRASTKPKDKGKITKRVKAKKNAAPFRSEVCFGKEGLWKLLGGFQETCS 240

Query: 241 KAIRVGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSMQVVPLDKQITIIDSPSFIVS 300
           KAIRVGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSMQVVPLDKQITIIDSPSFIVS
Sbjct: 241 KAIRVGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSMQVVPLDKQITIIDSPSFIVS 300

Query: 301 PLNSSSALALRSPASIEVVKPMEAASAILSQADARQVVLKYTVPGYRNSLEFFTVLAQRR 360
           PLNSSSALALRSPASIEVVKPMEAASAILSQADARQVVLKYTVPGYRNSLEFFTVLAQRR
Sbjct: 301 PLNSSSALALRSPASIEVVKPMEAASAILSQADARQVVLKYTVPGYRNSLEFFTVLAQRR 360

Query: 361 GMHQKGGIPNVEGAAKLLWSEWTGASLAYYCHPPTSWTPPPYFNESIVVDMKSGFNLEEL 420
           GMHQKGGIPNVEGAAKLLWSEWTGASLAYYCHPPTSWTPPPYFNESIVVDMKSGFNLEEL
Sbjct: 361 GMHQKGGIPNVEGAAKLLWSEWTGASLAYYCHPPTSWTPPPYFNESIVVDMKSGFNLEEL 420

Query: 421 EKNNAQSIRAIKGPHLANSILFQSSGLTNGIIEEKDIHEELPKRKERKQEEREDDKDSDQ 480
           EKNNAQSIRAIKGPHLANSILFQSSGLTNGIIEEKDIHEELPKRKERKQEEREDDKDSDQ
Sbjct: 421 EKNNAQSIRAIKGPHLANSILFQSSGLTNGIIEEKDIHEELPKRKERKQEEREDDKDSDQ 480

Query: 481 ETVDEEVDENSSGMFAAEETGEALSEETTAGEQSTRSFILDKIIEEDDAYDFSTDYV 537
           ETVDEEVDENSSGMFAAEETGEALSEETTAGEQSTRSFILDKIIEEDDAYDFSTDYV
Sbjct: 481 ETVDEEVDENSSGMFAAEETGEALSEETTAGEQSTRSFILDKIIEEDDAYDFSTDYV 537


>gi|45593130 guanine nucleotide binding protein-like 3 isoform 1
           [Homo sapiens]
          Length = 549

 Score = 1066 bits (2756), Expect = 0.0
 Identities = 537/537 (100%), Positives = 537/537 (100%)

Query: 1   MTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLE 60
           MTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLE
Sbjct: 13  MTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLE 72

Query: 61  ELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQ 120
           ELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQ
Sbjct: 73  ELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQ 132

Query: 121 ELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLILNKSDLVPKENLESWL 180
           ELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLILNKSDLVPKENLESWL
Sbjct: 133 ELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLILNKSDLVPKENLESWL 192

Query: 181 NYLKKELPTVVFRASTKPKDKGKITKRVKAKKNAAPFRSEVCFGKEGLWKLLGGFQETCS 240
           NYLKKELPTVVFRASTKPKDKGKITKRVKAKKNAAPFRSEVCFGKEGLWKLLGGFQETCS
Sbjct: 193 NYLKKELPTVVFRASTKPKDKGKITKRVKAKKNAAPFRSEVCFGKEGLWKLLGGFQETCS 252

Query: 241 KAIRVGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSMQVVPLDKQITIIDSPSFIVS 300
           KAIRVGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSMQVVPLDKQITIIDSPSFIVS
Sbjct: 253 KAIRVGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSMQVVPLDKQITIIDSPSFIVS 312

Query: 301 PLNSSSALALRSPASIEVVKPMEAASAILSQADARQVVLKYTVPGYRNSLEFFTVLAQRR 360
           PLNSSSALALRSPASIEVVKPMEAASAILSQADARQVVLKYTVPGYRNSLEFFTVLAQRR
Sbjct: 313 PLNSSSALALRSPASIEVVKPMEAASAILSQADARQVVLKYTVPGYRNSLEFFTVLAQRR 372

Query: 361 GMHQKGGIPNVEGAAKLLWSEWTGASLAYYCHPPTSWTPPPYFNESIVVDMKSGFNLEEL 420
           GMHQKGGIPNVEGAAKLLWSEWTGASLAYYCHPPTSWTPPPYFNESIVVDMKSGFNLEEL
Sbjct: 373 GMHQKGGIPNVEGAAKLLWSEWTGASLAYYCHPPTSWTPPPYFNESIVVDMKSGFNLEEL 432

Query: 421 EKNNAQSIRAIKGPHLANSILFQSSGLTNGIIEEKDIHEELPKRKERKQEEREDDKDSDQ 480
           EKNNAQSIRAIKGPHLANSILFQSSGLTNGIIEEKDIHEELPKRKERKQEEREDDKDSDQ
Sbjct: 433 EKNNAQSIRAIKGPHLANSILFQSSGLTNGIIEEKDIHEELPKRKERKQEEREDDKDSDQ 492

Query: 481 ETVDEEVDENSSGMFAAEETGEALSEETTAGEQSTRSFILDKIIEEDDAYDFSTDYV 537
           ETVDEEVDENSSGMFAAEETGEALSEETTAGEQSTRSFILDKIIEEDDAYDFSTDYV
Sbjct: 493 ETVDEEVDENSSGMFAAEETGEALSEETTAGEQSTRSFILDKIIEEDDAYDFSTDYV 549


>gi|9506611 guanine nucleotide binding protein-like 3
           (nucleolar)-like [Homo sapiens]
          Length = 582

 Score =  282 bits (721), Expect = 6e-76
 Identities = 162/425 (38%), Positives = 256/425 (60%), Gaps = 11/425 (2%)

Query: 17  HRKLR----KEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQQQKLDRQK 72
           H+K+     + AK+ G K   K P  P+     +   REAEL+K+ +EE++++Q+  R++
Sbjct: 18  HKKISWPYPQPAKQNGKKATSKVPSAPHFVHPNDHANREAELKKKWVEEMREKQQAAREQ 77

Query: 73  ELEKKRKLETN-PDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQELKKVIEASDV 131
           E +K+R +E+   D+     E   KE  L +     +   + ++K Y +E +KV+E SDV
Sbjct: 78  ERQKRRTIESYCQDVLRRQEEFEHKEEVLQELNMFPQLDDEATRKAYYKEFRKVVEYSDV 137

Query: 132 VLEVLDARDPLGCRCPQVEEAIVQS-GQKKLVLILNKSDLVPKENLESWLNYLKKELPTV 190
           +LEVLDARDPLGCRC Q+EEA++++ G KKLVL+LNK DLVPKE +E WL+YL+ ELPTV
Sbjct: 138 ILEVLDARDPLGCRCFQMEEAVLRAQGNKKLVLVLNKIDLVPKEVVEKWLDYLRNELPTV 197

Query: 191 VFRASTKPKDKGKITKRVKAKK-NAAPFRSEVCFGKEGLWKLLGGFQET--CSKAIRVGV 247
            F+AST+ + K      V   + + +  +S+ CFG E L ++LG +         IRVGV
Sbjct: 198 AFKASTQHQVKNLNRCSVPVDQASESLLKSKACFGAENLMRVLGNYCRLGEVRTHIRVGV 257

Query: 248 IGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSMQVVPLDKQITIIDSPSFIVSPLNSSSA 307
           +G PNVGKSS+INSLK+ + C+VG   G+T+ MQ V LDK I ++D+P  +  P NS   
Sbjct: 258 VGLPNVGKSSLINSLKRSRACSVGAVPGITKFMQEVYLDKFIRLLDAPGIVPGP-NSEVG 316

Query: 308 LALRSPASIE-VVKPMEAASAILSQADARQVVLKYTVPGYRNSLEFFTVLAQRRGMHQKG 366
             LR+   ++ +  P+     IL + +  ++   Y V G++ +  F T +A R G  +KG
Sbjct: 317 TILRNCVHVQKLADPVTPVETILQRCNLEEISNYYGVSGFQTTEHFLTAVAHRLGKKKKG 376

Query: 367 GIPNVEGAAKLLWSEWTGASLAYYCHPPTSWTPPPYFNESIVVDMKSGFNLEELEKNNAQ 426
           G+ + E AAK + ++W    +++Y  PP + T P + +  IV +M   F++E+ E+ N  
Sbjct: 377 GLYSQEQAAKAVLADWVSGKISFYIPPPATHTLPTHLSAEIVKEMTEVFDIEDTEQANED 436

Query: 427 SIRAI 431
           ++  +
Sbjct: 437 TMECL 441


>gi|7019419 guanine nucleotide binding protein-like 2 (nucleolar)
           [Homo sapiens]
          Length = 731

 Score =  171 bits (434), Expect = 1e-42
 Identities = 122/421 (28%), Positives = 204/421 (48%), Gaps = 54/421 (12%)

Query: 102 KTENKAKSGKQNSKKLYCQELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQ-KK 160
           + E + +  K+   K    EL KVI++SDVV++VLDARDP+G R P +E  + +    K 
Sbjct: 190 RNEAQEEIYKKGQSKRIWGELYKVIDSSDVVVQVLDARDPMGTRSPHIETYLKKEKPWKH 249

Query: 161 LVLILNKSDLVPKENLESWLNYLKKELPTVVFRAS-TKPKDKGKITKRVKAKKNAAPFRS 219
           L+ +LNK DLVP    + W+  L ++ PT+ F AS T P  KG   + ++          
Sbjct: 250 LIFVLNKCDLVPTWATKRWVAVLSQDYPTLAFHASLTNPFGKGAFIQLLRQ--------- 300

Query: 220 EVCFGKEGLWKLLGGFQETCSKAIRVGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRS 279
              FGK            T  K I VG IG+PNVGKSS+IN+L+ +++CNV    G T+ 
Sbjct: 301 ---FGK----------LHTDKKQISVGFIGYPNVGKSSVINTLRSKKVCNVAPIAGETKV 347

Query: 280 MQVVPLDKQITIIDSPSFIVSPLNSSSALALRSPASIEVVK-PMEAASAILSQADARQVV 338
            Q + L ++I +ID P  +    +S + + L+    +E +K P +   A+L +A    + 
Sbjct: 348 WQYITLMRRIFLIDCPGVVYPSEDSETDIVLKGVVQVEKIKSPEDHIGAVLERAKPEYIS 407

Query: 339 LKYTVPGYRNSLEFFTVLAQRRGMHQKGGIPNVEGAAKLLWSEWTGASLAYYCHPPTS-- 396
             Y +  + N+ +F   LA R G   KGG P+++   K++ ++W    + ++  PP +  
Sbjct: 408 KTYKIDSWENAEDFLEKLAFRTGKLLKGGEPDLQTVGKMVLNDWQRGRIPFFVKPPNAEP 467

Query: 397 -WTPPPYFNESIVVDMKSGFN------------------LEELEKNN--------AQSIR 429
              P    + S+ V  ++  N                   EE E+N+         Q + 
Sbjct: 468 LVAPQLLPSSSLEVVPEAAQNNPGEEVTETAGEGSESIIKEETEENSHCDANTEMQQILT 527

Query: 430 AIKGPHLANSILFQSSGLTNGIIEEKDIHEELPKRKERKQEEREDDKDSDQETVDEEVDE 489
            ++      +++ Q SG     +E  D+ EEL    + ++EE+E  +D  +E+  E  +E
Sbjct: 528 RVRQNFGKINVVPQFSGDDLVPVEVSDLEEELESFSDEEEEEQEQQRDDAEESSSEPEEE 587

Query: 490 N 490
           N
Sbjct: 588 N 588


>gi|93277113 GTP_binding protein [Homo sapiens]
          Length = 334

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 57/194 (29%), Positives = 95/194 (48%), Gaps = 29/194 (14%)

Query: 120 QELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLILNKSDLVPKENLESW 179
           ++++  ++  D ++EV DAR PL  R P  +E +   G K  +L+LNK DL      +  
Sbjct: 40  KKMQSSLKLVDCIIEVHDARIPLSGRNPLFQETL---GLKPHLLVLNKMDLADLTEQQKI 96

Query: 180 LNYLKKE-LPTVVFRASTKPKDKGKITKRVKAKKNAAPFRSEVCFGKEGLWKLLGGFQET 238
           + +L+ E L  V+F    K ++  +I   V         RS     KE L        E 
Sbjct: 97  MQHLEGEGLKNVIFTNCVKDENVKQIIPMVTELIG----RSHRYHRKENL--------EY 144

Query: 239 CSKAIRVGVIGFPNVGKSSIINSLKQEQM-----CNVGVSMGLTRS-MQVVPLDKQ--IT 290
           C     + VIG PNVGKSS+INSL+++ +       VG   G+TR+ M  + + ++  + 
Sbjct: 145 C-----IMVIGVPNVGKSSLINSLRRQHLRKGKATRVGGEPGITRAVMSKIQVSERPLMF 199

Query: 291 IIDSPSFIVSPLNS 304
           ++D+P  +   + S
Sbjct: 200 LLDTPGVLAPRIES 213


>gi|223029424 large subunit GTPase 1 [Homo sapiens]
          Length = 658

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 40/134 (29%), Positives = 69/134 (51%), Gaps = 22/134 (16%)

Query: 60  EELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYC 119
           EELKQ +K      LE +R+L    + +   + P E+                     + 
Sbjct: 126 EELKQAEK---DNFLEWRRQLVRLEEEQKLILTPFERNLD------------------FW 164

Query: 120 QELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQ-SGQKKLVLILNKSDLVPKENLES 178
           ++L +VIE SD+V++++DAR+PL  RC  +E  + +    K+ V+++NK+DL+  E   +
Sbjct: 165 RQLWRVIERSDIVVQIVDARNPLLFRCEDLECYVKEMDANKENVILINKADLLTAEQRSA 224

Query: 179 WLNYLKKELPTVVF 192
           W  Y +KE   V+F
Sbjct: 225 WAMYFEKEDVKVIF 238



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 47/225 (20%), Positives = 98/225 (43%), Gaps = 18/225 (8%)

Query: 243 IRVGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSMQVVPLDKQITIIDSPSFIVSPL 302
           + VG++G+PNVGKSS IN++   +  +V  + G T+  Q + ++  + + D P  ++   
Sbjct: 387 LTVGLVGYPNVGKSSTINTIMGNKKVSVSATPGHTKHFQTLYVEPGLCLCDCPGLVMPSF 446

Query: 303 NSSSA-LALRSPASIEVVKPMEAASAILSQADARQVV-----LKYTVPGYRN-------S 349
            S+ A +       I+ ++      +++ Q   R V+     +    P           S
Sbjct: 447 VSTKAEMTCSGILPIDQMRDHVPPVSLVCQNIPRHVLEATYGINIITPREDEDPHRPPTS 506

Query: 350 LEFFTVLAQRRGMHQKGGIPNVEGAAKLLWSEWTGASLAYYCHPPTSWTPPPYFNESIVV 409
            E  T     RG     G P+   +A+ +  ++    L  YCHPP    P  + ++   +
Sbjct: 507 EELLTAYGYMRGFMTAHGQPDQPRSARYILKDYVSGKL-LYCHPPPGRDPVTFQHQHQRL 565

Query: 410 DMKSGFNLEELEKNNAQSIRAIKGPHLANSILFQSS---GLTNGI 451
            +++  N +E++    ++ +A +  ++ +   F       LT G+
Sbjct: 566 -LENKMNSDEIKMQLGRNKKAKQIENIVDKTFFHQENVRALTKGV 609


>gi|38788319 guanine nucleotide binding protein-like 1 [Homo
           sapiens]
          Length = 607

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 69/281 (24%), Positives = 103/281 (36%), Gaps = 53/281 (18%)

Query: 243 IRVGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSMQVVPLDKQITIIDSPSFIVSPL 302
           + +G +GFPNVGKSS+IN L   ++ +V  + G TR  Q   L   + + D P  I   L
Sbjct: 361 VTIGCVGFPNVGKSSLINGLVGRKVVSVSRTPGHTRYFQTYFLTPSVKLCDCPGLIFPSL 420

Query: 303 NSSSALALRSPASIEVVKPMEAASAILSQADARQVVLKYTVPGYRN--------SLEFFT 354
                  L     I  ++    A   L+     Q +L    P   +        + +   
Sbjct: 421 LPRQLQVLAGIYPIAQIQEPYTAVGYLASRIPVQALLHLRHPEAEDPSAEHPWCAWDICE 480

Query: 355 VLAQRRGMH-QKGGIPNVEGAAKLLWSEWTGASLAYYCHPP------TSWTPPPYFNESI 407
             A++RG    K    +V  AA  L        L+   HPP       +W   P   E +
Sbjct: 481 AWAEKRGYKTAKAARNDVYRAANSLLRLAVDGRLSLCFHPPGYSEQKGTWESHPETTELV 540

Query: 408 VVDMKSGFNLEELEKNNAQSIRAIKGPHLANSILFQSSGLTNGIIEEKDIHEELPKRKER 467
           V+  + G                              +G      EE++  EEL    E 
Sbjct: 541 VLQGRVG-----------------------------PAG-----DEEEEEEEELSSSCE- 565

Query: 468 KQEEREDDKDSDQE-TVDEEVDENSSGMFAAEETGEALSEE 507
             EE E+D+D+D+E   DEE   ++ G   A     AL  E
Sbjct: 566 --EEGEEDRDADEEGEGDEETPTSAPGSSLAGRNPYALLGE 604


>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 275

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 34/120 (28%), Positives = 58/120 (48%), Gaps = 4/120 (3%)

Query: 5   KRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQ 64
           KR + +K+ +E   K R++ KK   K+ RK  G       KE   RE E +++R    ++
Sbjct: 78  KRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRR----ER 133

Query: 65  QQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQELKK 124
           ++K  R+K+  K+RK E     +    +  +KE    K E   K  K+  ++   +E KK
Sbjct: 134 KRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKK 193



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 30/112 (26%), Positives = 56/112 (50%), Gaps = 5/112 (4%)

Query: 5   KRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQ 64
           ++ K +KK RE  ++ R+E KK   KK RK+    N    +    R+   +K+R +E K+
Sbjct: 95  RKRKKEKKKRERKQRGRRERKK---KKERKERERENKQ--RRERKRKKRRKKKRRKERKR 149

Query: 65  QQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKK 116
           +++  +++   KKRK E     +  N +  +KE    +   + K  K+  +K
Sbjct: 150 EKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRK 201



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 24/92 (26%), Positives = 44/92 (47%)

Query: 5   KRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQ 64
           KR K +KK R   RK  KE  KR  K+ ++          +    R+ E  ++   E K+
Sbjct: 134 KRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKK 193

Query: 65  QQKLDRQKELEKKRKLETNPDIKPSNVEPMEK 96
           ++K +R+K+ E+K+  +T+         P+ +
Sbjct: 194 ERKKERRKKKERKKDRKTDRQTDSQVFRPLRE 225



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 25/96 (26%), Positives = 49/96 (51%), Gaps = 3/96 (3%)

Query: 5   KRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEEL-- 62
           +R + +KK R+   +  K+ ++R  KK RK          KE   RE + +K++ EE   
Sbjct: 111 RRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREK 170

Query: 63  -KQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKE 97
            +++ + +R+KE E+K + E   + K    +  E++
Sbjct: 171 KRERNRKERKKERERKERRERKKERKKERRKKKERK 206



 Score = 37.7 bits (86), Expect = 0.027
 Identities = 29/123 (23%), Positives = 57/123 (46%), Gaps = 11/123 (8%)

Query: 5   KRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQ------- 57
           KR + +++ RE  +K +K+ KKR   K R+          KE   +E   RK+       
Sbjct: 47  KREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRER 106

Query: 58  ----RLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQN 113
               R E  K++++ +R++E +++R+ +     K    +  ++E    K E K K  K+ 
Sbjct: 107 KQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKE 166

Query: 114 SKK 116
            ++
Sbjct: 167 ERE 169



 Score = 33.9 bits (76), Expect = 0.39
 Identities = 25/112 (22%), Positives = 55/112 (49%), Gaps = 12/112 (10%)

Query: 5   KRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQ 64
           +R + +K+ RE  ++ ++E  K+  KK +K          +E        RK+R ++ K+
Sbjct: 39  ERREREKRKREREKERKRERGKKEKKKRKK----------RERGKERERKRKEREKQRKE 88

Query: 65  QQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKK 116
           +++ +R+K  ++K+K E     +       +KE    + ENK +  ++  K+
Sbjct: 89  RREKERRKRKKEKKKRERKQ--RGRRERKKKKERKERERENKQRRERKRKKR 138



 Score = 33.5 bits (75), Expect = 0.50
 Identities = 29/111 (26%), Positives = 52/111 (46%), Gaps = 4/111 (3%)

Query: 10  QKKVREHHRKL---RKEAKKRGHKKPRKDPGVPNSAPFKEAL-LREAELRKQRLEELKQQ 65
           +K+ RE  RK    +KE KKR  ++  K+         K+    RE E RK++ E+ K++
Sbjct: 46  RKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRE 105

Query: 66  QKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKK 116
           +K   ++E +KK++ +          E   K+    K   + K  K+  K+
Sbjct: 106 RKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKR 156



 Score = 30.8 bits (68), Expect = 3.3
 Identities = 33/114 (28%), Positives = 52/114 (45%), Gaps = 30/114 (26%)

Query: 3   CHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEEL 62
           C +R   +KK R       +E +KR  +K RK          +E   +E + RK+R E  
Sbjct: 29  CTQRESERKKERRE-----REKRKREREKERK----------RERGKKEKKKRKKR-ERG 72

Query: 63  KQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKK 116
           K++++  ++KE EK+RK            E  EKE    K E K +  KQ  ++
Sbjct: 73  KERER--KRKEREKQRK------------ERREKERRKRKKEKKKRERKQRGRR 112


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 49/201 (24%), Positives = 81/201 (40%), Gaps = 15/201 (7%)

Query: 12   KVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQQQKLDRQ 71
            KV+E  +K  +E      K   K       AP KEA   + E +K+   E  ++ K++ +
Sbjct: 834  KVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAK 893

Query: 72   K-ELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQELKKVIEASD 130
            K E E K+K+ T     P+ VE  E      K + K +  K+       +E  K  E  +
Sbjct: 894  KEEAEDKKKVPTPEKEAPAKVEVKED----AKPKEKTEVAKKEPDDAKAKEPSKPAEKKE 949

Query: 131  VVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLILNKSDLVPKENLESWLNYLKKELPTV 190
               E  D ++    + P+ E+   ++  K+    L+K    PK          K E  + 
Sbjct: 950  AAPEKKDTKEE-KAKKPE-EKPKTEAKAKEDDKTLSKEPSKPKAE--------KAEKSSS 999

Query: 191  VFRASTKPKDKGKITKRVKAK 211
              +  +KP +K    K  K K
Sbjct: 1000 TDQKDSKPPEKATEDKAAKGK 1020



 Score = 30.0 bits (66), Expect = 5.6
 Identities = 27/103 (26%), Positives = 43/103 (41%), Gaps = 7/103 (6%)

Query: 11   KKVREHHRKLRKEAKKRGHKKP-RKDPGVPNSAPFKEALLREAELRKQRLEELKQQQK-L 68
            K+  E  +K   +AK +   KP  K    P     KE   ++ E + +   + K+  K L
Sbjct: 923  KEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTL 982

Query: 69   DRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGK 111
             ++    K  K E +      + +P EK      TE+KA  GK
Sbjct: 983  SKEPSKPKAEKAEKSSSTDQKDSKPPEKA-----TEDKAAKGK 1020


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 66/313 (21%), Positives = 126/313 (40%), Gaps = 54/313 (17%)

Query: 21   RKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQQQKLDRQKELEKKRKL 80
            RKEAK RG K   K     +    +E    E E     L+EL++Q+ L  ++E E++ + 
Sbjct: 2200 RKEAK-RGDKPKEKFSSQVDEVESEEHFSEEME---SLLDELEKQESLSSEEEEEREEEE 2255

Query: 81   ETNPD-IKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQELKKVIEASDVVLEVLDAR 139
            E   + ++    E  E+E G  K   K +  K+  KK   ++ K+ ++  + V E     
Sbjct: 2256 EREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKK---EKKKEEVQEKEEVFE----- 2307

Query: 140  DPLGCRCPQVEEAIVQSGQKKLVLILNKSDLVPKENLESWLNYLKKELPTVVFRASTKPK 199
                                       K +++ +E  ES  +  ++E    +     + K
Sbjct: 2308 --------------------------EKEEIMSEEETESLSDEEEEEESCSLEEEVDREK 2341

Query: 200  DKGKITKRVKAKKNAAPFRSEVCFGKEGLWKLLGGFQETCSKAIRVGVIGFPNVGKSSII 259
            +  K  K+ K ++     R +   G+E +  +L G      +AIR+GV+  P   K  + 
Sbjct: 2342 EILKKEKQFKLQEQ----RRKSLRGRERVLSILRGVPHGKGRAIRLGVLKSPL--KKLMS 2395

Query: 260  NSLKQEQMCNVGVSMGLTRSMQVVPLDKQITIIDSPSFIVSPLNSSSALALRSPASIEVV 319
             +L+ ++   V V        Q+   DK+ T+++ P   +  ++    +        E +
Sbjct: 2396 TALEMKEKTPVPVP-----EKQISWEDKKATVVEIPRKFLGTMDKEREVM----GKYEPI 2446

Query: 320  KPMEAASAILSQA 332
             P    + + SQA
Sbjct: 2447 PPHVLGTVLESQA 2459



 Score = 33.9 bits (76), Expect = 0.39
 Identities = 56/253 (22%), Positives = 105/253 (41%), Gaps = 41/253 (16%)

Query: 12   KVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEEL-KQQQKLDR 70
            K+ E  +KL +E +    ++ +        A  +E L++E E   Q  E++ +++++L R
Sbjct: 1741 KLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGR 1800

Query: 71   QKE--LEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQELKKVIEA 128
            ++E  +EKK KL    +   +++E + K     K     K      KK   QE +K+ + 
Sbjct: 1801 KREQLIEKKMKLAQKRERWINSMEELTKN----KMILYQKKNLAQEKKNLAQEKEKLAQR 1856

Query: 129  SDVVL-----------EVLDARDPLGC---RCPQVEEAIVQ-------------SGQKKL 161
             + +L           +++  ++ LG       QVEE + Q               +KKL
Sbjct: 1857 KENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKL 1916

Query: 162  VLILNKSDLVPKENLESWLNYLKKELPTVVFRASTKPKDKGKITKRVKA----KKNAAPF 217
            V +    D + K+  +     +K  L   + +   + + +  I K  KA     K  A  
Sbjct: 1917 VQV---EDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNLEMKRLAEE 1973

Query: 218  RSEVCFGKEGLWK 230
            +  +  GKE L K
Sbjct: 1974 KMRLVEGKETLSK 1986



 Score = 33.1 bits (74), Expect = 0.66
 Identities = 18/75 (24%), Positives = 43/75 (57%), Gaps = 10/75 (13%)

Query: 453  EEKDIHEELPKRKERKQEEREDDKDSDQETVDEEVDENSSGMFAAEETGEALSEETTAGE 512
            EEK + +E  ++K++K+E+++++    +E  +E+ +        +EE  E+LS+E    E
Sbjct: 2276 EEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEE------IMSEEETESLSDE----E 2325

Query: 513  QSTRSFILDKIIEED 527
            +   S  L++ ++ +
Sbjct: 2326 EEEESCSLEEEVDRE 2340



 Score = 30.8 bits (68), Expect = 3.3
 Identities = 21/84 (25%), Positives = 40/84 (47%), Gaps = 4/84 (4%)

Query: 453  EEKDIHEELPKRKERKQEEREDDKDSDQETVDEEVDENSSGMFAAEETGEALSE-ETTAG 511
            EE+++ EE    +ERK+EE  ++K  ++E  +++  +        +E  E   E E    
Sbjct: 2258 EEEEVREE---EEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMS 2314

Query: 512  EQSTRSFILDKIIEEDDAYDFSTD 535
            E+ T S   ++  EE  + +   D
Sbjct: 2315 EEETESLSDEEEEEESCSLEEEVD 2338



 Score = 30.4 bits (67), Expect = 4.3
 Identities = 18/82 (21%), Positives = 44/82 (53%), Gaps = 6/82 (7%)

Query: 453  EEKDIHEELPKRKE---RKQEEREDDKDSDQETVDEEVDENSSGMFAAEETGEALSEETT 509
            E + + +EL K++     ++EERE++++ ++E V EE +E        E+  E   EE  
Sbjct: 2229 EMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKK 2288

Query: 510  AGEQSTRSFILDKIIEEDDAYD 531
              ++  +    +++ E+++ ++
Sbjct: 2289 KKKKEKKK---EEVQEKEEVFE 2307



 Score = 29.6 bits (65), Expect = 7.3
 Identities = 26/131 (19%), Positives = 66/131 (50%), Gaps = 11/131 (8%)

Query: 10   QKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQQQKLD 69
            +++ RE   + R+E + R  ++ RK+         ++ + +E E +K++ +E K+++  +
Sbjct: 2247 EEEEREEEEE-REEEEVREEEEERKE----EEEGEEKQVEKEEEEKKKKKKEKKKEEVQE 2301

Query: 70   RQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKK----LYCQELKKV 125
            +++  E+K ++ +  + +  + E  E+E   C  E +    K+  KK       ++ +K 
Sbjct: 2302 KEEVFEEKEEIMSEEETESLSDEEEEEE--SCSLEEEVDREKEILKKEKQFKLQEQRRKS 2359

Query: 126  IEASDVVLEVL 136
            +   + VL +L
Sbjct: 2360 LRGRERVLSIL 2370


>gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]
          Length = 1233

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 27/106 (25%), Positives = 52/106 (49%), Gaps = 1/106 (0%)

Query: 9   IQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQQQKL 68
           ++K  +E   ++ +E++ +G     ++  V      KE   + A    Q LE+  + QK 
Sbjct: 343 VEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKA 402

Query: 69  DRQK-ELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQN 113
           D+ + +LE+++K+ET   IK    E  E +  + K E    + KQ+
Sbjct: 403 DQDRLDLEERKKVETEAKIKQKLREIEENQKRIEKLEEYITTSKQS 448



 Score = 29.3 bits (64), Expect = 9.5
 Identities = 34/150 (22%), Positives = 68/150 (45%), Gaps = 34/150 (22%)

Query: 10  QKKVREHHRKLRKEAKKRG------------HKKPRKD-------PGVPNSAPFKEALLR 50
           + +V+++HR L++EA KR              +K  +D         V   A  K+ L R
Sbjct: 369 ENQVKKYHR-LKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKL-R 426

Query: 51  EAELRKQRLEELKQ-----QQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTE- 104
           E E  ++R+E+L++     +Q L+ QK+LE   +L    ++    ++ + KE      + 
Sbjct: 427 EIEENQKRIEKLEEYITTSKQSLEEQKKLE--GELTEEVEMAKRRIDEINKELNQVMEQL 484

Query: 105 -----NKAKSGKQNSKKLYCQELKKVIEAS 129
                ++ +S +Q  K    + +K++   S
Sbjct: 485 GDARIDRQESSRQQRKAEIMESIKRLYPGS 514


>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 245

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 27/112 (24%), Positives = 52/112 (46%)

Query: 5   KRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQ 64
           KR + +K+ +   +K  +E KKR  +K  K+         KE   R    ++ +  E K+
Sbjct: 78  KRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKE 137

Query: 65  QQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKK 116
           ++K + +KE E+K++       +    +   K+ G  + E K K  K+  K+
Sbjct: 138 ERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKR 189



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 30/113 (26%), Positives = 54/113 (47%), Gaps = 1/113 (0%)

Query: 5   KRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQ 64
           ++ K +KK ++   +  KE K+R  K+ RK          KE   +E E ++++  E KQ
Sbjct: 111 EKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQ 170

Query: 65  Q-QKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKK 116
             +K + +KE E+K + +   + K    E   KE    K E K K  ++  ++
Sbjct: 171 VGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQ 223



 Score = 38.1 bits (87), Expect = 0.020
 Identities = 28/118 (23%), Positives = 53/118 (44%), Gaps = 6/118 (5%)

Query: 5   KRYKIQKKVREHHRKLRKEAKKRGH------KKPRKDPGVPNSAPFKEALLREAELRKQR 58
           +R K  K+  E  ++ +KE K+RG       ++ RK+         +E    E E  ++R
Sbjct: 101 RREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERER 160

Query: 59  LEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKK 116
            E  K+++K   +KE E+K K       +  N +  +KE    +   + K  K+  ++
Sbjct: 161 KERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEER 218



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 29/107 (27%), Positives = 48/107 (44%), Gaps = 26/107 (24%)

Query: 10  QKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQQQKLD 69
           Q ++RE  R++  E +K G K+                  RE+E +K+R E  K      
Sbjct: 35  QSEIREREREI--ETRKEGKKE------------------RESERKKERREREK------ 68

Query: 70  RQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKK 116
           R++E EK+RK E     K    +  E+E    + E + K G++  K+
Sbjct: 69  RKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKR 115



 Score = 35.0 bits (79), Expect = 0.17
 Identities = 27/112 (24%), Positives = 57/112 (50%), Gaps = 7/112 (6%)

Query: 5   KRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQ 64
           +R + ++K RE  ++ R++ ++R  +K R+   V      KE   +E E RK+R +  ++
Sbjct: 138 ERKREERKERERKKEEREKERERKERKKRERKQVGE----KEEERKEKE-RKERKK--RE 190

Query: 65  QQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKK 116
           + + +R+KE E+K + E   + K       E++        + + GK+  K+
Sbjct: 191 RNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKE 242



 Score = 31.6 bits (70), Expect = 1.9
 Identities = 32/110 (29%), Positives = 55/110 (50%), Gaps = 15/110 (13%)

Query: 11  KKVREHHRKLRK---EAKKRGHKKPRK-DPGVPNSAPFKEALLREAELRKQRLEELKQQQ 66
           KK RE  RK  +   E +KR  +K RK + G       ++   RE + R+ R +E K+ +
Sbjct: 52  KKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRR-REKENKEGE 110

Query: 67  KLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKK 116
           + +++K+ EKK +  T+ + K       E+E    K E K +  K+  +K
Sbjct: 111 EKEKRKKKEKKERGRTSKEGK-------ERE---RKEERKREERKERERK 150


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 24/72 (33%), Positives = 44/72 (61%), Gaps = 1/72 (1%)

Query: 10  QKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQQQKLD 69
           +K+ R+    LRKE +K   ++P++   +         L R+ ELR++R EE +QQQ+L 
Sbjct: 243 EKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQ-ELRRERQEEEQQQQRLR 301

Query: 70  RQKELEKKRKLE 81
           R+++L +K++ E
Sbjct: 302 REQQLRRKQEEE 313



 Score = 34.3 bits (77), Expect = 0.29
 Identities = 31/134 (23%), Positives = 65/134 (48%), Gaps = 7/134 (5%)

Query: 10   QKKVREHHRKLRKEAKKRGHKKPRK----DPGVPNSAPFKEALLREAELRKQRLEELKQQ 65
            ++ +RE   K R++ ++R ++K +K    +  +    P K    +E E + +  EEL+Q+
Sbjct: 941  EQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRR-QEREKKYREEEELQQE 999

Query: 66   QKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQELKKV 125
            ++   ++E EK+R+ E     +  +    E+E  L   E + K   Q  ++ Y +E +  
Sbjct: 1000 EEQLLREEREKRRRQEWERQYRKKDELQQEEEQLL--REEREKRRLQERERQYREEEELQ 1057

Query: 126  IEASDVVLEVLDAR 139
             E   ++ E  + R
Sbjct: 1058 QEEEQLLGEERETR 1071



 Score = 33.5 bits (75), Expect = 0.50
 Identities = 15/83 (18%), Positives = 46/83 (55%)

Query: 5   KRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQ 64
           +  ++++K  E  R+ ++E +++  ++ +++         ++   RE +LR+++ EE ++
Sbjct: 302 REQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERRE 361

Query: 65  QQKLDRQKELEKKRKLETNPDIK 87
           QQ    Q+E  ++++L     ++
Sbjct: 362 QQLRREQEEERREQQLRREQQLR 384



 Score = 33.5 bits (75), Expect = 0.50
 Identities = 21/87 (24%), Positives = 48/87 (55%), Gaps = 4/87 (4%)

Query: 5    KRYKIQKKVREHHRKLRKEA--KKRGHKKPRKDPGVPNSAPFKEALLREAE--LRKQRLE 60
            ++Y+ +++V++   +L +E   K+R  +  R+          +E LLRE +   R++R  
Sbjct: 1138 RQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERER 1197

Query: 61   ELKQQQKLDRQKELEKKRKLETNPDIK 87
            + +++++L RQK  ++ R  +   D+K
Sbjct: 1198 QYREEEELQRQKRKQRYRDEDQRSDLK 1224



 Score = 33.1 bits (74), Expect = 0.66
 Identities = 19/92 (20%), Positives = 51/92 (55%), Gaps = 8/92 (8%)

Query: 10  QKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQ----RLEELKQQ 65
           Q+  RE   + R++  +R  ++ R++  +      ++ L RE +LR++    R ++L+++
Sbjct: 349 QQLRREQEEERREQQLRREQEEERREQQLRR----EQQLRREQQLRREQQLRREQQLRRE 404

Query: 66  QKLDRQKELEKKRKLETNPDIKPSNVEPMEKE 97
           Q+L R+++L ++++L     ++    E   ++
Sbjct: 405 QQLRREQQLRREQQLRREQQLRREQEEERHEQ 436



 Score = 32.7 bits (73), Expect = 0.86
 Identities = 20/83 (24%), Positives = 48/83 (57%), Gaps = 3/83 (3%)

Query: 5    KRYKIQKKVREHHRKLRKEA--KKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEEL 62
            ++Y+ ++++++   +L +E   K+R  ++ R+          +E LLRE E  K+R +EL
Sbjct: 1078 RQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLRE-EREKRRRQEL 1136

Query: 63   KQQQKLDRQKELEKKRKLETNPD 85
            ++Q + + + + E+++ L   P+
Sbjct: 1137 ERQYREEEEVQQEEEQLLREEPE 1159



 Score = 31.2 bits (69), Expect = 2.5
 Identities = 32/156 (20%), Positives = 72/156 (46%), Gaps = 5/156 (3%)

Query: 10   QKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLR---EAELRKQRLEELKQQQ 66
            ++ +RE   K R + ++R +++  +          +E   R   E E + ++ EEL+Q++
Sbjct: 1031 EQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEE 1090

Query: 67   KLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQELKKVI 126
            +   ++E EK+R+ E     +    E +++E      E + K  +Q  ++ Y +E +   
Sbjct: 1091 EQLLREEPEKRRRQERERQCREE--EELQQEEEQLLREEREKRRRQELERQYREEEEVQQ 1148

Query: 127  EASDVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLV 162
            E   ++ E  + R          EE  +Q  +++L+
Sbjct: 1149 EEEQLLREEPEKRRRQELERQYREEEELQQEEEQLL 1184



 Score = 31.2 bits (69), Expect = 2.5
 Identities = 28/128 (21%), Positives = 60/128 (46%), Gaps = 20/128 (15%)

Query: 5    KRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLE-ELK 63
            +R +  +K RE  ++LR++ ++R                  + L  E +LR+Q LE + +
Sbjct: 1685 RRQERDRKFREEEQQLRRQERER------------------KFLQEEQQLRRQELERKFR 1726

Query: 64   QQQKLDRQKELEKKRKLETNPDI-KPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQEL 122
            ++++L ++ E E+ R+ E    I +   + P  +E  L + E   K  ++   +   +E 
Sbjct: 1727 EEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQ 1786

Query: 123  KKVIEASD 130
            +   + SD
Sbjct: 1787 QLRSQESD 1794



 Score = 30.8 bits (68), Expect = 3.3
 Identities = 29/120 (24%), Positives = 60/120 (50%), Gaps = 9/120 (7%)

Query: 8   KIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLRE--AELRKQRLEELKQQ 65
           K +++     ++LR+E ++R  ++ +++         ++ L RE   E R+Q L E +Q+
Sbjct: 635 KSEEQEERRQQQLRREQQERREQRLKREE---EEERLEQRLKREHEEERREQELAEEEQE 691

Query: 66  QKLDRQKELEKK--RKLETNPDIKPSNV--EPMEKEFGLCKTENKAKSGKQNSKKLYCQE 121
           Q  +R K    K   +LE+  D + S V   P ++E    + E + K  ++ S+  + +E
Sbjct: 692 QARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEE 751



 Score = 30.4 bits (67), Expect = 4.3
 Identities = 20/103 (19%), Positives = 57/103 (55%), Gaps = 7/103 (6%)

Query: 10  QKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQQQKLD 69
           Q++++E   +LRK  ++   ++ +++         ++ L RE +LR+++ EE ++QQ+ +
Sbjct: 268 QRELQEEEEQLRKLERQELRRERQEEEQQ------QQRLRREQQLRRKQEEERREQQE-E 320

Query: 70  RQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQ 112
           R+++ E++ + E   + +    +   +E  L + + + +  +Q
Sbjct: 321 RREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQ 363



 Score = 30.4 bits (67), Expect = 4.3
 Identities = 18/70 (25%), Positives = 38/70 (54%), Gaps = 2/70 (2%)

Query: 18  RKLRKEAKKRGHKKPRKDPGVPNSAPFK--EALLREAELRKQRLEELKQQQKLDRQKELE 75
           ++LR+E + R  ++ R++  +      +  + L RE +LR+++ EE  +Q+    ++E  
Sbjct: 387 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQR 446

Query: 76  KKRKLETNPD 85
            KR+ E   D
Sbjct: 447 LKREQEERRD 456



 Score = 30.4 bits (67), Expect = 4.3
 Identities = 24/117 (20%), Positives = 55/117 (47%), Gaps = 12/117 (10%)

Query: 5   KRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQ 64
           +R + +++  + H + R+E + +  ++ R+D            L RE E  +   E  KQ
Sbjct: 426 RREQEEERHEQKHEQERREQRLKREQEERRD-----------WLKREEETERHEQERRKQ 474

Query: 65  QQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQE 121
           Q K D+++E  ++R L+   + +    E  E++    + E + +  K+  ++   Q+
Sbjct: 475 QLKRDQEEE-RRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQ 530



 Score = 30.0 bits (66), Expect = 5.6
 Identities = 36/152 (23%), Positives = 67/152 (44%), Gaps = 20/152 (13%)

Query: 5    KRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLE-ELK 63
            +R + Q++ ++   +L +E K+R H    K P +      ++ LL+E E   QR E E +
Sbjct: 863  RRSQEQRRDQKWRWQLEEERKRRRHTLYAK-PALQEQLRKEQQLLQEEEEELQREEREKR 921

Query: 64   QQQKLDRQ----------------KELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKA 107
            ++Q+ +RQ                +E EK+R+ E     +       ++E  L   E   
Sbjct: 922  RRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLL--GEEPE 979

Query: 108  KSGKQNSKKLYCQELKKVIEASDVVLEVLDAR 139
            K  +Q  +K Y +E +   E   ++ E  + R
Sbjct: 980  KRRRQEREKKYREEEELQQEEEQLLREEREKR 1011



 Score = 30.0 bits (66), Expect = 5.6
 Identities = 18/77 (23%), Positives = 44/77 (57%), Gaps = 1/77 (1%)

Query: 5    KRYKIQKKVR-EHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELK 63
            K+Y+ +++++ E  + LR+E +KR  ++  +     +    +E  L   E  K+RL+E +
Sbjct: 988  KKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERE 1047

Query: 64   QQQKLDRQKELEKKRKL 80
            +Q + + + + E+++ L
Sbjct: 1048 RQYREEEELQQEEEQLL 1064



 Score = 30.0 bits (66), Expect = 5.6
 Identities = 27/116 (23%), Positives = 56/116 (48%), Gaps = 15/116 (12%)

Query: 9    IQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQQQK- 67
            +Q  + E   + R++ ++R  ++ R  P        +E L RE +   +R +   Q++K 
Sbjct: 1267 LQHLLGEQQERDREQERRRWQQRDRHFPE-------EEQLEREEQKEAKRRDRKSQEEKQ 1319

Query: 68   LDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQELK 123
            L R++  EK+R+ ET+   +       E+E  L + E +    ++  +K   +EL+
Sbjct: 1320 LLREEREEKRRRQETDRKFR-------EEEQLLQEREEQPLRRQERDRKFREEELR 1368



 Score = 29.6 bits (65), Expect = 7.3
 Identities = 22/106 (20%), Positives = 57/106 (53%), Gaps = 11/106 (10%)

Query: 14  REHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQQQKLDRQKE 73
           RE  ++L +E +++  K+ +++         ++ LL+  E R+Q+  + +Q+++L+++ +
Sbjct: 552 REEEKRLEQERREQRLKREQEER--------RDQLLKREEERRQQRLKREQEERLEQRLK 603

Query: 74  LEKKRKLETNP--DIKPSNVEP-MEKEFGLCKTENKAKSGKQNSKK 116
            E+  +LE     + +    EP  E+   L K+E + +  +Q  ++
Sbjct: 604 REEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRR 649



 Score = 29.3 bits (64), Expect = 9.5
 Identities = 24/103 (23%), Positives = 51/103 (49%), Gaps = 13/103 (12%)

Query: 8   KIQKKVREHHRKLRKEAKKRGHKKPRKDPGVP-------NSAPFKEALLR--EAELRKQR 58
           K +++   H ++ RK+  KR  ++ R++  +             +E  LR  + E R+QR
Sbjct: 459 KREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQR 518

Query: 59  L----EELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKE 97
           L    EE + QQ+L  +++L ++++      +K    + +E+E
Sbjct: 519 LKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQE 561



 Score = 29.3 bits (64), Expect = 9.5
 Identities = 20/95 (21%), Positives = 45/95 (47%), Gaps = 3/95 (3%)

Query: 3    CHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEEL 62
            C +  ++Q+   E  + LR+E +KR  ++  +          +E  L   E  K+R +EL
Sbjct: 1110 CREEEELQQ---EEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQEL 1166

Query: 63   KQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKE 97
            ++Q + + + + E+++ L    + +    E   +E
Sbjct: 1167 ERQYREEEELQQEEEQLLREEQEKRRQERERQYRE 1201



 Score = 29.3 bits (64), Expect = 9.5
 Identities = 20/80 (25%), Positives = 43/80 (53%), Gaps = 5/80 (6%)

Query: 10   QKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQQQKLD 69
            Q + +E +RK+ +E + R  ++ ++         F+E    E +LR++R E+  + Q+ D
Sbjct: 1739 QLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFRE----EEQLRQEREEQQLRSQESD 1794

Query: 70   RQ-KELEKKRKLETNPDIKP 88
            R+ +E E+ R+      ++P
Sbjct: 1795 RKFREEEQLRQEREEQQLRP 1814


>gi|4503179 oral-facial-digital syndrome 1 [Homo sapiens]
          Length = 1012

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 32/128 (25%), Positives = 64/128 (50%), Gaps = 5/128 (3%)

Query: 10  QKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQQQKLD 69
           QK++ E   + +   ++   ++ R++    N     E   RE E   Q  + +++  K+ 
Sbjct: 870 QKQIEEQKEEEKIREQQVKERRQREERRQSNLQEVLERERRELEKLYQERKMIEESLKIK 929

Query: 70  RQKELEKKRKLE-TNPDIKPSNVE---PMEKEFGLCKTENKAKSGKQNSKKLYCQ-ELKK 124
            +KELE + +LE +N +IK  +     P+EK   + + E   +S  ++SKK+  +  L  
Sbjct: 930 IKKELEMENELEMSNQEIKDKSAHSENPLEKYMKIIQQEQDQESADKSSKKMVQEGSLVD 989

Query: 125 VIEASDVV 132
            +++SD V
Sbjct: 990 TLQSSDKV 997


>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
          Length = 2468

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 50/207 (24%), Positives = 83/207 (40%), Gaps = 49/207 (23%)

Query: 10  QKKVREHHRKLRKEAKKRGHKKPRKDPGVP-NSAPFKEALLREAELRKQRLEELKQQQKL 68
           ++K  +   K++ E KK   +KP+K+     +  P K+         K + EE+K++ K 
Sbjct: 634 KEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKE-------EKPKKEEVKKEVKK 686

Query: 69  DRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQELKKVIEA 128
           + +KE +K+ K E   +  P  V+   K     K E K    ++   K   ++L K  + 
Sbjct: 687 EIKKEEKKEPKKEVKKETPPKEVKKEVK-----KEEKKEVKKEEKEPKKEIKKLPKDAKK 741

Query: 129 SDVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLILNKSDLVPKENLESWLNYLKKELP 188
           S   L        L  + P+ EE++             K D V                 
Sbjct: 742 SSTPLSEAKKPAALKPKVPKKEESV-------------KKDSV----------------- 771

Query: 189 TVVFRASTKPKDKGKITKRVKAKKNAA 215
                A+ KPK+KGKI K +K +  AA
Sbjct: 772 -----AAGKPKEKGKI-KVIKKEGKAA 792



 Score = 38.1 bits (87), Expect = 0.020
 Identities = 35/129 (27%), Positives = 65/129 (50%), Gaps = 12/129 (9%)

Query: 9   IQKKVREHHRKLRKEAKKRGHKKPRKDP--GVPNSAPFKEALLREAELRKQRLEELKQQQ 66
           I+K+ +    +++KE KK   K+ +K+P   V    P KE    + E++K+  +E+K+++
Sbjct: 669 IKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEV---KKEVKKEEKKEVKKEE 725

Query: 67  KLDRQ--KELEKKRKLETNP---DIKPSNVEPM--EKEFGLCKTENKAKSGKQNSKKLYC 119
           K  ++  K+L K  K  + P     KP+ ++P   +KE  + K    A   K+  K    
Sbjct: 726 KEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESVKKDSVAAGKPKEKGKIKVI 785

Query: 120 QELKKVIEA 128
           ++  K  EA
Sbjct: 786 KKEGKAAEA 794



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 43/209 (20%), Positives = 90/209 (43%), Gaps = 28/209 (13%)

Query: 19  KLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQQQKLDRQKELEKKR 78
           KL++ A  R   KP   P +P+ +  KE+     E+ K  +  +++  K++ ++++  K+
Sbjct: 534 KLKQRADSRESLKPAAKP-LPSKSVRKESKEETPEVTK--VNHVEKPPKVESKEKVMVKK 590

Query: 79  ----KLETNPDIK----PSNVEPMEKEFGLCK---TENKAKSGKQNS----KKLYCQELK 123
               K ET P +     PS  EP   +  + +   T+ K K+ K+ +     K+  ++ K
Sbjct: 591 DKPIKTETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKK 650

Query: 124 KVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLILNKSDLVPKENLESWLNYL 183
           +  E     +   + + P+       +E + +  +K+          + KE  +     +
Sbjct: 651 EEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKE----------IKKEEKKEPKKEV 700

Query: 184 KKELPTVVFRASTKPKDKGKITKRVKAKK 212
           KKE P    +   K ++K ++ K  K  K
Sbjct: 701 KKETPPKEVKKEVKKEEKKEVKKEEKEPK 729



 Score = 31.6 bits (70), Expect = 1.9
 Identities = 27/110 (24%), Positives = 50/110 (45%), Gaps = 13/110 (11%)

Query: 9    IQKKVREHHRKLRKEAKKRGHKKPRKDPGV--PNSAPFKEALLREAELRKQRLEELKQQQ 66
            ++K ++E  +  +   K +     +K  G   P +A  K A L+E+  +  R+   K+++
Sbjct: 2235 LKKDLKEKTKTKKPGTKTKSSSPVKKSDGKSKPLAASPKPAGLKESSDKVSRVASPKKKE 2294

Query: 67   KLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKK 116
             +      EK  K  T P++K +  E  +KE     T+N A +    S K
Sbjct: 2295 SV------EKAAKPTTTPEVKAARGEEKDKE-----TKNAANASASKSAK 2333


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 25/87 (28%), Positives = 45/87 (51%), Gaps = 9/87 (10%)

Query: 452 IEEKDIHEEL---PKRKERKQEEREDDKDSDQETVDEEVDENSSGMFAAEETGEALSEET 508
           +E   +H E+   P+ +E ++EE E+D++S++E  +E   E S G    +E  E +S+E 
Sbjct: 518 VEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEG----DEEDEKVSDEK 573

Query: 509 TAGEQSTRSFILDKIIEEDDAYDFSTD 535
            +G+   +     K +  D  YD   D
Sbjct: 574 DSGKTLDKK--PSKEMSSDSEYDSDDD 598



 Score = 39.3 bits (90), Expect = 0.009
 Identities = 36/131 (27%), Positives = 60/131 (45%), Gaps = 12/131 (9%)

Query: 14  REHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEAL--LREAELRKQRLEELKQQQKLDRQ 71
           ++  +K +K  K+   K+ +K P        +EAL  L+E E R++R EE    +++ R 
Sbjct: 314 KKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEE----ERIKRL 369

Query: 72  KELEKKRK----LETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQELKKVIE 127
           +ELE KRK    LE     +    E   KE    K E K  +  Q   +   +   K+++
Sbjct: 370 EELEAKRKEEERLEQEKRERKKQKEKERKE--RLKKEGKLLTKSQREARARAEATLKLLQ 427

Query: 128 ASDVVLEVLDA 138
           A  V +   D+
Sbjct: 428 AQGVEVPSKDS 438



 Score = 30.4 bits (67), Expect = 4.3
 Identities = 19/79 (24%), Positives = 37/79 (46%), Gaps = 7/79 (8%)

Query: 453 EEKDIHEELPKRKERKQEEREDDKDSDQETVDEEVDENSSGMFAAEETGEALSEETTAGE 512
           EE++  EE  + +E ++EE E +     E  ++  DE  SG    ++  + +S ++    
Sbjct: 536 EEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDS 595

Query: 513 QSTRSFILDKIIEEDDAYD 531
              R+       +E+ AYD
Sbjct: 596 DDDRT-------KEERAYD 607


>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 668

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 29/131 (22%), Positives = 67/131 (51%), Gaps = 14/131 (10%)

Query: 5   KRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQ 64
           K ++ ++K+RE   K+R++ KK   ++ +           ++  +RE E R+++ E  +Q
Sbjct: 417 KMWRQEEKIREQEEKIREQEKKMWRQEEKIH---------EQEKIREEEKRQEQEEMWRQ 467

Query: 65  QQKLDRQKEL-EKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQELK 123
           ++K+  Q+E+  +K K+     I+    +   +E  +   E K    ++  +K++ QE +
Sbjct: 468 EEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKI---REQEEKMWRQE-E 523

Query: 124 KVIEASDVVLE 134
           K+ E  + + E
Sbjct: 524 KIREQEEKIRE 534



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 27/133 (20%), Positives = 65/133 (48%), Gaps = 14/133 (10%)

Query: 5   KRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQ 64
           K ++ ++K+RE   K+R++ +K   ++             +E +  + ++R+Q  +  +Q
Sbjct: 517 KMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQ 576

Query: 65  QQKLDRQKE---------LEKKRKLETNPDIKPSNVEPM-EKEFGLCKTENKAKSG---- 110
           ++K+  QKE          E++ K+    ++     E M E+E  +C+ E K +      
Sbjct: 577 EEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKM 636

Query: 111 KQNSKKLYCQELK 123
           ++  +K++ QE++
Sbjct: 637 RRQEEKMWEQEVR 649



 Score = 32.7 bits (73), Expect = 0.86
 Identities = 22/116 (18%), Positives = 61/116 (52%), Gaps = 3/116 (2%)

Query: 10  QKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQQQKLD 69
           Q+K+RE   K ++E K R  +K R++         ++   +E ++R+Q  +  +Q++K+ 
Sbjct: 389 QEKIREQEEKRQEEEKIREQEK-RQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIH 447

Query: 70  RQKELEKKRKLETNPDI--KPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQELK 123
            Q+++ ++ K +   ++  +   +   E+ +   +  ++ +  ++  +K++ QE K
Sbjct: 448 EQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEK 503



 Score = 30.0 bits (66), Expect = 5.6
 Identities = 25/86 (29%), Positives = 43/86 (50%), Gaps = 11/86 (12%)

Query: 453 EEKDIHEELPKRKERKQEE-----REDDKDSDQETVDEEVDENSSGMFAAEE---TGEAL 504
           EEK   EE  + +E++QE+     R+++K  +QE   E++ E    M+  EE     E +
Sbjct: 396 EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE---EKIREQEKKMWRQEEKIHEQEKI 452

Query: 505 SEETTAGEQSTRSFILDKIIEEDDAY 530
            EE    EQ       +KI E+++ +
Sbjct: 453 REEEKRQEQEEMWRQEEKIREQEEIW 478


>gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens]
          Length = 1759

 Score = 40.0 bits (92), Expect = 0.005
 Identities = 24/85 (28%), Positives = 43/85 (50%), Gaps = 2/85 (2%)

Query: 430  AIKGPHLANSILFQSSGLTNGIIEEKDIHEELPKRKERKQEEREDDKDSDQETVDEEVDE 489
            A  GP    +    ++G ++   EE+++  ELP+ +    E+ +DD+D D E  DE+ D+
Sbjct: 1655 AAPGPREGAAAAAAAAGESSQEDEEEEL--ELPEEEAEDDEDEDDDEDDDDEDDDEDDDD 1712

Query: 490  NSSGMFAAEETGEALSEETTAGEQS 514
                  + E   EA +E   AG ++
Sbjct: 1713 EDLRTDSEESLPEAAAEAAGAGART 1737


>gi|88759339 aster-associated protein [Homo sapiens]
          Length = 647

 Score = 40.0 bits (92), Expect = 0.005
 Identities = 34/125 (27%), Positives = 65/125 (52%), Gaps = 7/125 (5%)

Query: 7   YKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQQQ 66
           ++  K ++E   K +  AKKR  +K +K     N+A   EAL    + +++++E LK++ 
Sbjct: 473 FEAWKAMKEKEAK-KIAAKKRLEEKNKKKTEEENAARKGEALQAFEKWKEKKMEYLKEKN 531

Query: 67  KLDRQKELEKKRK-LETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQELKKV 125
           + +R+ E  KK+K  ET  + K  N+  +EK       E K    KQ  K+   ++ K+ 
Sbjct: 532 RKEREYERAKKQKEEETVAEKKKDNLTAVEK-----WNEKKEAFFKQKEKEKINEKRKEE 586

Query: 126 IEASD 130
           ++ ++
Sbjct: 587 LKRAE 591


>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 750

 Score = 39.7 bits (91), Expect = 0.007
 Identities = 27/121 (22%), Positives = 63/121 (52%), Gaps = 14/121 (11%)

Query: 5   KRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQ 64
           K ++ ++K+RE   K+R++ KK   ++ +           ++  +RE E R+++ E  +Q
Sbjct: 431 KMWRQEEKIREQEEKIREQEKKMWRQEEKIH---------EQEKIREEEKRQEQEEMWRQ 481

Query: 65  QQKLDRQKEL--EKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQEL 122
           ++K+  Q+E+  +K++  E    I+    +   +E  + + E K    ++  +K++ QE 
Sbjct: 482 EEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKI---REQEEKMWRQEE 538

Query: 123 K 123
           K
Sbjct: 539 K 539



 Score = 34.3 bits (77), Expect = 0.29
 Identities = 23/119 (19%), Positives = 59/119 (49%), Gaps = 9/119 (7%)

Query: 10  QKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQQQKLD 69
           ++K+RE   K+R++ +    ++ +           +E +  + E   ++ E++++Q+K  
Sbjct: 625 EEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKI 684

Query: 70  RQKELEKKRKLETNPDIKPSNVEPM-EKEFGLCKTENKAKSG----KQNSKKLYCQELK 123
           R++E     K+    ++     E M E+E  +C+ E K +      ++  +K++ QE++
Sbjct: 685 REQE----EKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVR 739



 Score = 33.5 bits (75), Expect = 0.50
 Identities = 33/141 (23%), Positives = 61/141 (43%), Gaps = 15/141 (10%)

Query: 5   KRYKIQKKVREHHRKLRKEAKKRGHKK---PRKDPGVPNSAPFKEALLREAELRKQRLEE 61
           K ++ ++K+RE     R+E K    +K     K     +    +E  +RE E +  R EE
Sbjct: 532 KMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEE 591

Query: 62  LKQQQKLDRQKELEKKRKLETNPDIKPSNVEPME----------KEFGLCKTENKAKSGK 111
             ++Q+  RQ++ EK  K E     +   ++  E          +E      E + K G+
Sbjct: 592 KIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGE 651

Query: 112 QNSKKLYCQELKKVIEASDVV 132
           Q  K   C++ +K+ E  + +
Sbjct: 652 QEEK--MCEQEEKMQEQEETM 670



 Score = 31.6 bits (70), Expect = 1.9
 Identities = 17/77 (22%), Positives = 43/77 (55%), Gaps = 1/77 (1%)

Query: 10  QKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQQQKLD 69
           Q+K+RE   K ++E K R  +K R++         ++   +E ++R+Q  +  +Q++K+ 
Sbjct: 403 QEKIREQEEKRQEEEKIREQEK-RQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIH 461

Query: 70  RQKELEKKRKLETNPDI 86
            Q+++ ++ K +   ++
Sbjct: 462 EQEKIREEEKRQEQEEM 478



 Score = 30.0 bits (66), Expect = 5.6
 Identities = 25/86 (29%), Positives = 43/86 (50%), Gaps = 11/86 (12%)

Query: 453 EEKDIHEELPKRKERKQEE-----REDDKDSDQETVDEEVDENSSGMFAAEE---TGEAL 504
           EEK   EE  + +E++QE+     R+++K  +QE   E++ E    M+  EE     E +
Sbjct: 410 EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE---EKIREQEKKMWRQEEKIHEQEKI 466

Query: 505 SEETTAGEQSTRSFILDKIIEEDDAY 530
            EE    EQ       +KI E+++ +
Sbjct: 467 REEEKRQEQEEMWRQEEKIHEQEEIW 492


>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
          Length = 793

 Score = 39.3 bits (90), Expect = 0.009
 Identities = 52/229 (22%), Positives = 93/229 (40%), Gaps = 33/229 (14%)

Query: 4   HKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNS---------APFKEALLREAEL 54
           H++ + + K R    + R EA++R   K  +D  + +          A  +E   REAE 
Sbjct: 254 HEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEE 313

Query: 55  RKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNS 114
           R++  EE K+  +  ++ + E+KR  E    IK       E+   + + E +A   +Q +
Sbjct: 314 RERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRA 373

Query: 115 KKLYCQELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLILNKSDLVPKE 174
           +    +E  KV E                 R  Q+EE      + K+     K + V ++
Sbjct: 374 RAEE-EEKAKVEEQK---------------RNKQLEEKKHAMQETKI-----KGEKVEQK 412

Query: 175 NLESWLNYLKKE---LPTVVFRASTKPKDKGKITKRVKAKKNAAPFRSE 220
               W+N  K +   L T V +   + K      KR K +++   F+ E
Sbjct: 413 IEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKE 461



 Score = 33.5 bits (75), Expect = 0.50
 Identities = 43/175 (24%), Positives = 78/175 (44%), Gaps = 23/175 (13%)

Query: 10  QKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQQQKLD 69
           +K+  E  +++++E K+   ++ R       +A  ++    E E  K ++EE K      
Sbjct: 335 EKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEE-EKAKVEEQK------ 387

Query: 70  RQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQELKKVIEAS 129
           R K+LE+K+       IK   VE  +K  G    E KA+       KL    LKK  +  
Sbjct: 388 RNKQLEEKKHAMQETKIKGEKVE--QKIEGKWVNEKKAQ-----EDKLQTAVLKK--QGE 438

Query: 130 DVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLILNKSDLVPKENLESWLNYLK 184
           +   +V   R+ L    P  ++  ++   +K+     K D  PKE ++S+++  K
Sbjct: 439 EKGTKVQAKREKLQEDKPTFKKEEIK--DEKI-----KKDKEPKEEVKSFMDRKK 486



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 41/197 (20%), Positives = 77/197 (39%), Gaps = 33/197 (16%)

Query: 10  QKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAP--------------------FKEALL 49
           +++ R+   + ++E +  G    + +    NS P                    F E L 
Sbjct: 42  RRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLA 101

Query: 50  REAELRKQRLEELKQQQK------LDRQKELEKKR----KLETNPDIKPSNVEPMEKEFG 99
           R  E R++RL+E  ++QK       D    L  +R      E     K    E  ++ + 
Sbjct: 102 RREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYE 161

Query: 100 LCKTENKAKSGKQNSKKLYCQELKKVIEASDVVLEVLDARDPLGCRCPQ--VEEAIVQSG 157
           + +TE   KS ++N  +   +E KK  +  +   E    R  +G    +  VEE   +S 
Sbjct: 162 IEETETVTKSYQKNDWR-DAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQ 220

Query: 158 QKKLVLILNKSDLVPKE 174
           ++ +V+ L    +  +E
Sbjct: 221 EETVVMSLKNGQISSEE 237



 Score = 29.6 bits (65), Expect = 7.3
 Identities = 17/64 (26%), Positives = 29/64 (45%)

Query: 454 EKDIHEELPKRKERKQEEREDDKDSDQETVDEEVDENSSGMFAAEETGEALSEETTAGEQ 513
           E +  E + + ++R  EER+  K+ ++   +E          AAEE      EE  A E+
Sbjct: 310 EAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEE 369

Query: 514 STRS 517
             R+
Sbjct: 370 RQRA 373



 Score = 29.3 bits (64), Expect = 9.5
 Identities = 20/64 (31%), Positives = 29/64 (45%), Gaps = 3/64 (4%)

Query: 453 EEKDIHEELPKRKERKQEEREDDKDSDQETVDEEVDENSSGMFAAEETGEALSEETTAGE 512
           EEK   +E   R+ R+ EERE  ++ ++   +E          AAEE      EE  A E
Sbjct: 298 EEKAAAQE---RERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAE 354

Query: 513 QSTR 516
           +  R
Sbjct: 355 ERQR 358


>gi|94680976 coiled-coil domain containing 112 isoform 1 [Homo
           sapiens]
          Length = 529

 Score = 38.9 bits (89), Expect = 0.012
 Identities = 26/86 (30%), Positives = 43/86 (50%), Gaps = 2/86 (2%)

Query: 7   YKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQQQ 66
           Y  QKK +E   +L KE +++  K  ++       + F+E  L + EL K    + K+ +
Sbjct: 404 YTQQKKEQEEFLRLEKEIREKAEKAEKRKNAADEISRFQERDLHKLEL-KILDRQAKEDE 462

Query: 67  KLDRQKELEK-KRKLETNPDIKPSNV 91
           K  +Q+ L K K K+E N    PS +
Sbjct: 463 KSQKQRRLAKLKEKVENNVSRDPSRL 488


>gi|145580595 coiled-coil domain containing 112 isoform 2 [Homo
           sapiens]
          Length = 446

 Score = 38.9 bits (89), Expect = 0.012
 Identities = 26/86 (30%), Positives = 43/86 (50%), Gaps = 2/86 (2%)

Query: 7   YKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQQQ 66
           Y  QKK +E   +L KE +++  K  ++       + F+E  L + EL K    + K+ +
Sbjct: 321 YTQQKKEQEEFLRLEKEIREKAEKAEKRKNAADEISRFQERDLHKLEL-KILDRQAKEDE 379

Query: 67  KLDRQKELEK-KRKLETNPDIKPSNV 91
           K  +Q+ L K K K+E N    PS +
Sbjct: 380 KSQKQRRLAKLKEKVENNVSRDPSRL 405


>gi|24308223 hypothetical protein LOC57577 [Homo sapiens]
          Length = 936

 Score = 38.9 bits (89), Expect = 0.012
 Identities = 40/175 (22%), Positives = 77/175 (44%), Gaps = 25/175 (14%)

Query: 14  REHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQQQKLDRQKE 73
           R   R++  E KK    K  ++      A  +E   REAE ++ +LE  +++++L + KE
Sbjct: 668 RAECRRILAEKKK----KQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKKMKE 723

Query: 74  LEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQELKKVIEASDVVL 133
           LEK+++++ N  ++    E  E+           K G +  K+L  Q  + +  A +   
Sbjct: 724 LEKQKRIKRNQQLEAIAKEHYERVL-------LRKKGLEPWKRLRMQSKQNIQVAEEHYS 776

Query: 134 EVLDARDPLGCRCPQVEEAIVQSGQKKLVLILNKSD-----LVPKENLESWLNYL 183
             L  +  L            Q  Q+ L   + ++D     ++ K  ++SWL Y+
Sbjct: 777 LFLQRKYML---------TWFQRSQESLARKMAQADQFYSQILLKRVIQSWLQYV 822



 Score = 29.3 bits (64), Expect = 9.5
 Identities = 24/62 (38%), Positives = 33/62 (53%), Gaps = 7/62 (11%)

Query: 25  KKRGHKKPRKDPGVPNSAPFKEA----LLREAELRKQRLEE-LKQQQKLDRQ--KELEKK 77
           K+   KK +KDP +      K+     L RE EL  QR+E+ LK+   L+ Q   + EKK
Sbjct: 177 KENQDKKQQKDPRLTMEMRHKQVKENRLRREKELEYQRIEKTLKKSAFLEAQCLVQEEKK 236

Query: 78  RK 79
           RK
Sbjct: 237 RK 238


>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
           protein 6 [Homo sapiens]
          Length = 724

 Score = 38.5 bits (88), Expect = 0.016
 Identities = 25/127 (19%), Positives = 66/127 (51%), Gaps = 8/127 (6%)

Query: 5   KRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQ 64
           K ++ ++K+RE   K+R++ +K   ++             +E +  + E  +++ E++++
Sbjct: 579 KVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRR 638

Query: 65  QQKLDRQKE---LEKKRKLETNPDIKPSNVEPM-EKEFGLCKTENKAKSG----KQNSKK 116
           Q++  R++E    E++ K+    ++     E M E+E  +C+ E K +      ++  +K
Sbjct: 639 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 698

Query: 117 LYCQELK 123
           ++ QE++
Sbjct: 699 MWEQEVR 705



 Score = 36.6 bits (83), Expect = 0.059
 Identities = 28/132 (21%), Positives = 68/132 (51%), Gaps = 15/132 (11%)

Query: 5   KRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQ 64
           K ++ ++K+RE   K+R++ +K   ++ +           ++  +RE E R+++ E  +Q
Sbjct: 478 KMWRQEEKIREQEEKIREQEEKMWRQEEKIH---------EQEKIREEEKRQEQEEMWRQ 528

Query: 65  QQKLDRQKEL--EKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQEL 122
           ++K+  Q+E+  +K++  E    I+    +   +E  +   E K    ++  +K++ QE 
Sbjct: 529 EEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKI---REQEEKVWRQE- 584

Query: 123 KKVIEASDVVLE 134
           +K+ E  + + E
Sbjct: 585 EKIREQEEKIRE 596



 Score = 31.6 bits (70), Expect = 1.9
 Identities = 19/88 (21%), Positives = 47/88 (53%), Gaps = 1/88 (1%)

Query: 10  QKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQQQKLD 69
           Q+K+RE   K ++E K R  +K R++         ++   +E ++R+Q  +  +Q++K+ 
Sbjct: 450 QEKIREQEEKRQEEEKIREQEK-RQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIH 508

Query: 70  RQKELEKKRKLETNPDIKPSNVEPMEKE 97
            Q+++ ++ K +   ++     +  E+E
Sbjct: 509 EQEKIREEEKRQEQEEMWRQEEKIREQE 536



 Score = 30.0 bits (66), Expect = 5.6
 Identities = 25/86 (29%), Positives = 43/86 (50%), Gaps = 11/86 (12%)

Query: 453 EEKDIHEELPKRKERKQEE-----REDDKDSDQETVDEEVDENSSGMFAAEE---TGEAL 504
           EEK   EE  + +E++QE+     R+++K  +QE   E++ E    M+  EE     E +
Sbjct: 457 EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE---EKIREQEEKMWRQEEKIHEQEKI 513

Query: 505 SEETTAGEQSTRSFILDKIIEEDDAY 530
            EE    EQ       +KI E+++ +
Sbjct: 514 REEEKRQEQEEMWRQEEKIREQEEIW 539


>gi|154354979 myosin X [Homo sapiens]
          Length = 2058

 Score = 38.5 bits (88), Expect = 0.016
 Identities = 40/155 (25%), Positives = 72/155 (46%), Gaps = 33/155 (21%)

Query: 4   HKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELK 63
           +++   +K+ +E  +K  +E KK+  ++ R+          +E   REAELR Q+ EE +
Sbjct: 808 YRQLLAEKREQEEKKKQEEEEKKKREEEERE----------RERERREAELRAQQEEETR 857

Query: 64  QQQKLDR----------QKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQN 113
           +QQ+L+            +ELEK+++   N  ++   +  +EKE      E+  +  +Q 
Sbjct: 858 KQQELEALQKSQKEAELTRELEKQKE---NKQVE--EILRLEKEI-----EDLQRMKEQQ 907

Query: 114 SKKLYCQELKKVIEASDVVLEVLDARDPLGCRCPQ 148
              L    L+K+ E  D  L  L+      CR  Q
Sbjct: 908 ELSLTEASLQKLQERRDQELRRLEEE---ACRAAQ 939


>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
          Length = 2817

 Score = 38.5 bits (88), Expect = 0.016
 Identities = 35/152 (23%), Positives = 73/152 (48%), Gaps = 7/152 (4%)

Query: 8   KIQKKVREHHRKLRKEAKKR-GHKKPRKDP--GVPNSAPFKEALLREAELRK--QRLEEL 62
           + +K+  E  R++ ++ K     K  R D   G+    P  E + RE E  K  +R +EL
Sbjct: 461 RARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEI-REREREKEREREKEL 519

Query: 63  KQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKS-GKQNSKKLYCQE 121
           +++Q+ +R+KE EK R+ +   + +    +  ++E    + + K K   +Q  K+   Q+
Sbjct: 520 EKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQK 579

Query: 122 LKKVIEASDVVLEVLDARDPLGCRCPQVEEAI 153
           +K+  +  ++  E     + +  R P +E  +
Sbjct: 580 MKEQEKECELEKEREKLEEKIEPREPNLEPMV 611



 Score = 38.1 bits (87), Expect = 0.020
 Identities = 32/133 (24%), Positives = 62/133 (46%), Gaps = 24/133 (18%)

Query: 6   RYKIQKKVREHHRKLRKEAKKRGHKKPRKDPG--VPNSAPFKEALLREAELRKQRLEELK 63
           R + ++K RE  ++L KE ++   K+  KD           ++   ++ E+ K+R +E  
Sbjct: 505 REREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQE-- 562

Query: 64  QQQKLDRQKELEK-----------------KRKLETNPDIKPSNVEPM---EKEFGLCKT 103
           ++++L+RQKE EK                 + KLE   + +  N+EPM   ++    C  
Sbjct: 563 KEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNK 622

Query: 104 ENKAKSGKQNSKK 116
           E +    +Q+S +
Sbjct: 623 EEEPVFTRQDSNR 635



 Score = 37.0 bits (84), Expect = 0.046
 Identities = 28/111 (25%), Positives = 57/111 (51%), Gaps = 2/111 (1%)

Query: 15  EHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEAL-LREAELRKQRLEELKQQQKLDRQKE 73
           E  RK R+E ++R  ++ RK           E L + E +   + + E +++++ +R+KE
Sbjct: 460 ERARKRREEEERRMEEQ-RKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKE 518

Query: 74  LEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQELKK 124
           LEK+++ E   + +       EKE  L K + K +  ++  K+   +EL++
Sbjct: 519 LEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELER 569



 Score = 30.8 bits (68), Expect = 3.3
 Identities = 14/40 (35%), Positives = 25/40 (62%)

Query: 450 GIIEEKDIHEELPKRKERKQEEREDDKDSDQETVDEEVDE 489
           GI+E++   EE+ +R+  K+ ERE + + +QE   E+  E
Sbjct: 493 GILEKQPSPEEIREREREKEREREKELEKEQEQEREKERE 532


>gi|16262452 cingulin [Homo sapiens]
          Length = 1203

 Score = 38.1 bits (87), Expect = 0.020
 Identities = 40/138 (28%), Positives = 68/138 (49%), Gaps = 23/138 (16%)

Query: 8   KIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQQQK 67
           ++ +KV E  RKL +E KKR   +P        S    E  L E      RL+EL +++K
Sbjct: 363 ELTRKVEELQRKLDEEVKKRQKLEP--------SQVGLERQLEEKTEECSRLQELLERRK 414

Query: 68  LDRQ---KELEK-KRKLETNPDIKPSNVEPMEKEFGLCKTENKAK--SGKQNSKKLYCQE 121
            + Q   KEL+  KR L+   D++         E  + + +NK K   G + +K++    
Sbjct: 415 GEAQQSNKELQNMKRLLDQGEDLRHG------LETQVMELQNKLKHVQGPEPAKEVL--- 465

Query: 122 LKKVIEASDVVLEVLDAR 139
           LK ++E  +++ EVL+ +
Sbjct: 466 LKDLLETRELLEEVLEGK 483


>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
          Length = 484

 Score = 38.1 bits (87), Expect = 0.020
 Identities = 26/101 (25%), Positives = 44/101 (43%), Gaps = 13/101 (12%)

Query: 11  KKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQQQKLDR 70
           KK R   RKL +    R HKK +K               ++ E  +   E    ++K  +
Sbjct: 356 KKPRSPKRKLSRSPSPRRHKKEKKKD-------------KDKERSRDERERSTSKKKKSK 402

Query: 71  QKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGK 111
            KE +++RK E++ D+K    +  E+E G    + K +  K
Sbjct: 403 DKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKK 443



 Score = 30.0 bits (66), Expect = 5.6
 Identities = 21/100 (21%), Positives = 45/100 (45%), Gaps = 8/100 (8%)

Query: 17  HRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQQQKLDRQKELEK 76
           HR+ R  +++R H K R      +    K    R +  R++        +  D++KE ++
Sbjct: 266 HRRSRSRSRRRSHSKSR------SRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKE 319

Query: 77  KRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKK 116
           K++ +T P  K  +     +     +   +++SG ++ KK
Sbjct: 320 KKRSKTPP--KSYSTARRSRSASRERRRRRSRSGTRSPKK 357


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.130    0.366 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,052,484
Number of Sequences: 37866
Number of extensions: 1009583
Number of successful extensions: 11571
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 198
Number of HSP's successfully gapped in prelim test: 382
Number of HSP's that attempted gapping in prelim test: 7601
Number of HSP's gapped (non-prelim): 3235
length of query: 537
length of database: 18,247,518
effective HSP length: 107
effective length of query: 430
effective length of database: 14,195,856
effective search space: 6104218080
effective search space used: 6104218080
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.