Guide to the Human Genome
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Search of human proteins with 131889391

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|131889391 hypothetical protein LOC55216 isoform a [Homo
sapiens]
         (293 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|131889432 hypothetical protein LOC55216 isoform a [Homo sapiens]   591   e-169
gi|131889391 hypothetical protein LOC55216 isoform a [Homo sapiens]   591   e-169
gi|131888281 hypothetical protein LOC55216 isoform b [Homo sapiens]   585   e-167
gi|168229156 NFKB activating protein [Homo sapiens]                    74   1e-13
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1...    70   2e-12
gi|27734775 hypothetical protein LOC286499 [Homo sapiens]              66   4e-11
gi|56090620 NFKB activating protein-like [Homo sapiens]                65   5e-11
gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]    61   1e-09
gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]    61   1e-09
gi|4557509 cylicin 2 [Homo sapiens]                                    57   1e-08
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]            55   6e-08
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]            55   1e-07
gi|151301228 formin binding protein 3 [Homo sapiens]                   54   1e-07
gi|40068059 CBF1 interacting corepressor [Homo sapiens]                54   2e-07
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi...    54   2e-07
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    54   2e-07
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s...    54   2e-07
gi|42560244 peptidylprolyl isomerase G [Homo sapiens]                  53   3e-07
gi|50409756 SRp25 nuclear protein isoform 1 [Homo sapiens]             53   3e-07
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ...    53   4e-07
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [...    53   4e-07
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap...    52   5e-07
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]           52   8e-07
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]           52   8e-07
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]    51   1e-06
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]    51   1e-06
gi|33457330 tetratricopeptide repeat domain 14 isoform a [Homo s...    51   1e-06
gi|50409738 SRp25 nuclear protein isoform 3 [Homo sapiens]             51   1e-06
gi|104526627 triadin [Homo sapiens]                                    51   1e-06
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ...    51   1e-06

>gi|131889432 hypothetical protein LOC55216 isoform a [Homo sapiens]
          Length = 293

 Score =  591 bits (1523), Expect = e-169
 Identities = 293/293 (100%), Positives = 293/293 (100%)

Query: 1   MSRIPLGKVLLRNVIRHTDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMR 60
           MSRIPLGKVLLRNVIRHTDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMR
Sbjct: 1   MSRIPLGKVLLRNVIRHTDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMR 60

Query: 61  SDGFDEESQRYYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEE 120
           SDGFDEESQRYYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEE
Sbjct: 61  SDGFDEESQRYYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEE 120

Query: 121 FETDSSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDI 180
           FETDSSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDI
Sbjct: 121 FETDSSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDI 180

Query: 181 TADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSE 240
           TADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSE
Sbjct: 181 TADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSE 240

Query: 241 ESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD 293
           ESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD
Sbjct: 241 ESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD 293


>gi|131889391 hypothetical protein LOC55216 isoform a [Homo sapiens]
          Length = 293

 Score =  591 bits (1523), Expect = e-169
 Identities = 293/293 (100%), Positives = 293/293 (100%)

Query: 1   MSRIPLGKVLLRNVIRHTDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMR 60
           MSRIPLGKVLLRNVIRHTDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMR
Sbjct: 1   MSRIPLGKVLLRNVIRHTDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMR 60

Query: 61  SDGFDEESQRYYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEE 120
           SDGFDEESQRYYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEE
Sbjct: 61  SDGFDEESQRYYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEE 120

Query: 121 FETDSSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDI 180
           FETDSSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDI
Sbjct: 121 FETDSSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDI 180

Query: 181 TADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSE 240
           TADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSE
Sbjct: 181 TADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSE 240

Query: 241 ESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD 293
           ESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD
Sbjct: 241 ESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD 293


>gi|131888281 hypothetical protein LOC55216 isoform b [Homo sapiens]
          Length = 292

 Score =  585 bits (1507), Expect = e-167
 Identities = 292/293 (99%), Positives = 292/293 (99%), Gaps = 1/293 (0%)

Query: 1   MSRIPLGKVLLRNVIRHTDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMR 60
           MSRIPLGKVLLRNVIRHTDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMR
Sbjct: 1   MSRIPLGKVLLRNVIRHTDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMR 60

Query: 61  SDGFDEESQRYYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEE 120
           SDGFDEESQRYYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEE
Sbjct: 61  SDGFDEESQRYYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEE 120

Query: 121 FETDSSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDI 180
           FETDS DQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDI
Sbjct: 121 FETDS-DQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDI 179

Query: 181 TADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSE 240
           TADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSE
Sbjct: 180 TADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSE 239

Query: 241 ESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD 293
           ESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD
Sbjct: 240 ESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD 292


>gi|168229156 NFKB activating protein [Homo sapiens]
          Length = 415

 Score = 74.3 bits (181), Expect = 1e-13
 Identities = 59/227 (25%), Positives = 97/227 (42%), Gaps = 24/227 (10%)

Query: 43  AYRGTKRKMLPSSSSRMRSDGFDEESQRYYW----------RPKNEISGTLEDDFLKAKS 92
           +YR   R       S  R   F   S   Y+          +P   +     ++ L+ K 
Sbjct: 71  SYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDKEREESLRQKR 130

Query: 93  WNKKFYDYEANMPDRWGHSGYKELYPEEFETDSSDQQDITNGKKTSPQVKSSTHESRKHK 152
            +++    E   P+ WG      L P+  E DS +   + + +       +ST E  K K
Sbjct: 131 LSERERIGELGAPEVWG------LSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKKK 184

Query: 153 KSKKSH---KKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKK 209
           KS +S    KK++KK+S K++ K   E +D  +DS ++ S+E      +K K+  K+KK 
Sbjct: 185 KSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKH 244

Query: 210 SRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKRE 256
             KK  KK      ++ +   S DS+S  S+E    +  K + K  E
Sbjct: 245 RSKKYKKK-----RSKKSRKESSDSSSKESQEEFLENPWKDRTKAEE 286



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 26/82 (31%), Positives = 39/82 (47%), Gaps = 14/82 (17%)

Query: 122 ETDSSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDIT 181
           ETDSSD+ +    KK   + K   H S+K+KK              K+ KKS+KE++D +
Sbjct: 220 ETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKK--------------KRSKKSRKESSDSS 265

Query: 182 ADSSSEFSEETGASGTRKGKQP 203
           +  S E   E       K ++P
Sbjct: 266 SKESQEEFLENPWKDRTKAEEP 287



 Score = 35.0 bits (79), Expect = 0.078
 Identities = 32/166 (19%), Positives = 65/166 (39%), Gaps = 17/166 (10%)

Query: 145 THESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSS----EFSEETGASGTRKG 200
           TH+     +  ++   + + RS  +++ S        + SSS     +S   G+      
Sbjct: 57  THQLGGLSQGSRNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPS 116

Query: 201 KQPHKRKKKSRKKSLKK---------PALFLEAESNTSHSDDSASSSSEESEERDTKKTK 251
               +R++  R+K L +         P ++  +  N     D  +   +E  ++ T    
Sbjct: 117 LLDKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSAS 176

Query: 252 RKKREKKAHTSVANNEIQER----TNKRTNWKVATDERSAESSEDD 293
             + EKK  +S +    ++R    ++KR + K + D  S   SE D
Sbjct: 177 TSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETD 222


>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
           [Homo sapiens]
          Length = 651

 Score = 70.5 bits (171), Expect = 2e-12
 Identities = 50/183 (27%), Positives = 81/183 (44%), Gaps = 9/183 (4%)

Query: 117 YPEEFETDSSDQQDITNGKKTSPQVKSSTHESRKHKK---SKKSHKKKQKKRSHKKQKKS 173
           YPE  +T+S D +D  N  +   +   +  + +  KK   S  S  + + K S K +KK 
Sbjct: 366 YPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKDEKKD 425

Query: 174 KKEATDITADSSSEFSEETGASG-----TRKGKQPHKRKKKSRKKSLKKPALFLEAESNT 228
           KK++      S     E T A       ++KGK+  K+ KK  KK  KK      AES  
Sbjct: 426 KKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTE 485

Query: 229 SHSDDSASSSSEES-EERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSA 287
             SD       + S E++ +KK  +K   K   ++ A  +   +T  +T+ K+   +  +
Sbjct: 486 MESDLELKKDKKHSKEKKGSKKDIKKDARKDTESTDAEFDESSKTGFKTSTKIKGSDTES 545

Query: 288 ESS 290
           E S
Sbjct: 546 EES 548



 Score = 52.0 bits (123), Expect = 6e-07
 Identities = 45/169 (26%), Positives = 74/169 (43%), Gaps = 19/169 (11%)

Query: 133 NGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEET 192
           N KK+S    + + +S+  KK  K  KK  KK   KK  K   E+TD  +  S +  ++T
Sbjct: 291 NAKKSSD---AESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDT 347

Query: 193 GASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKR 252
                   K   K KK  +KK  KK     + ES  +    + S + +++ + D KK   
Sbjct: 348 K-------KDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDA 400

Query: 253 KK--------REKKAHTSVANNEIQERTNKRTNWK-VATDERSAESSED 292
           KK         E ++  S  + +  ++ +K  N K V  DE S ++  +
Sbjct: 401 KKITFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSE 449



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 68/259 (26%), Positives = 113/259 (43%), Gaps = 18/259 (6%)

Query: 32  KIRELEKQME--DAYRGT---KRKMLPSSSSRMRSDGFDEESQRYYWRPKNEISGTLED- 85
           K ++++K  E  DA  G    +RK       +++ D   +++++Y      E SG  +D 
Sbjct: 322 KKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTE-SGDAKDA 380

Query: 86  --DFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSS-DQQDI-TNGKKTSPQV 141
             D    K  +K     +      +      EL  +E + D   D++D  T+ KK+    
Sbjct: 381 RNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKND 440

Query: 142 KSSTH---ESRKHKKSKKSHKKKQKKRSHK--KQKKSKKEATDITADSSSEFSEETGASG 196
           + ST    E +   K  K  +KK KK S K  K+K +KK A     +S  E  ++   S 
Sbjct: 441 EESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKKDKKHSK 500

Query: 197 TRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKRE 256
            +KG +    KK +RK +    A F E+      +      S  ESEE   K   +KK +
Sbjct: 501 EKKGSK-KDIKKDARKDTESTDAEFDESSKTGFKTSTKIKGSDTESEESLYKPGAKKKID 559

Query: 257 KKAHTSVANNEIQERTNKR 275
           +   TS AN++++   +KR
Sbjct: 560 ESDGTS-ANSKMEGLESKR 577



 Score = 48.1 bits (113), Expect = 9e-06
 Identities = 38/162 (23%), Positives = 70/162 (43%), Gaps = 16/162 (9%)

Query: 135 KKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGA 194
           KK +    + + +S+  +K  K  KKK KK   KK  K   E+TD         +E   A
Sbjct: 327 KKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTD---------TESGDA 377

Query: 195 SGTRKGKQPHKRKKKS--RKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKR 252
              R   +  K+  K+  +KK  KK     ++ES     +   S   E+ +++D+K   +
Sbjct: 378 KDARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKE---SQKDEKKDKKDSKTDNK 434

Query: 253 KKREKKAHTSVANNEIQ--ERTNKRTNWKVATDERSAESSED 292
           K  +    ++ A++E +   +  K+   K   D +  +  +D
Sbjct: 435 KSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKD 476



 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 43/210 (20%), Positives = 78/210 (37%), Gaps = 20/210 (9%)

Query: 91  KSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSSDQQDITNGKKTSPQVKS------- 143
           +S N K      +  D+      K+   E   T ++ ++D+   K ++  +         
Sbjct: 184 ESQNSKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSENSL 243

Query: 144 ----------STHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETG 193
                     S  ES       +++ +   K    K  K  K+ T   A  SS+   E  
Sbjct: 244 NVDFLMLVGQSDDESINFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDS 303

Query: 194 ASGTRKGKQPHKR-KKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKR 252
               +  K+  K  KK  +KK +KK     +AES  S  +   +   ++  ++D KK   
Sbjct: 304 KDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDT 363

Query: 253 KKREKKAHTSVANNEIQERTNKRTNWKVAT 282
           KK  +   T   + + ++  N   N K A+
Sbjct: 364 KKYPES--TDTESGDAKDARNDSRNLKKAS 391



 Score = 34.3 bits (77), Expect = 0.13
 Identities = 47/254 (18%), Positives = 92/254 (36%), Gaps = 45/254 (17%)

Query: 83  LEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSSDQQDITNGKK------ 136
           +   F K   W   +       P R  ++    L   E++  S D++  T  KK      
Sbjct: 77  IRHSFRKILQWPPIYTAAREQTPFRHLYTSKTHLKKAEYKK-SKDEKGGTPLKKDSKKKG 135

Query: 137 ----TSPQVKSSTHESRKHKKS------KKSHKKKQKKRSHKKQKKSKKEATDITADSSS 186
               T+P+ K    E  K +        K SH+ +Q K+S    + + +     T   + 
Sbjct: 136 GSYATNPESKQIVEEKTKRQNEADKTPLKSSHENEQSKKSKSSSETNPESQNSKTVSKNC 195

Query: 187 EFSEETGASGTRKGKQPHKRKKKSRKKSLKK------PALFLEAESN--------TSHSD 232
              ++  +  ++K        K + KK LK+      P   + +E++           SD
Sbjct: 196 SQKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSENSLNVDFLMLVGQSD 255

Query: 233 DSA--------SSSSEESEERDTKKTKRKKREKKAHTSVANNEIQE------RTNKRTNW 278
           D +        + S   S+    K TK  K++ K +   +++   E      + +K+   
Sbjct: 256 DESINFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKK 315

Query: 279 KVATDERSAESSED 292
            V  D++  +  +D
Sbjct: 316 NVKKDDKKKDVKKD 329


>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
          Length = 248

 Score = 65.9 bits (159), Expect = 4e-11
 Identities = 54/204 (26%), Positives = 84/204 (41%), Gaps = 16/204 (7%)

Query: 69  QRYYWRPK---NEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGH----SGYKELYPEEF 121
           Q Y  RP+    E+   LE+     K+ +K   ++E  M + W      S  K L   E 
Sbjct: 31  QDYLNRPRPTWEEVKKQLENK----KTGSKALAEFEEKMNENWKKELEKSREKLLSGNES 86

Query: 122 ETDSSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDIT 181
            +   +++     K       SS+ +S       +  +KKQ KR  KK+ +S K +   T
Sbjct: 87  SSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSST 146

Query: 182 ADSSSEFSE-----ETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSAS 236
            +S SE  E     +     T K K      KK +K       L  E+ S + + +D  +
Sbjct: 147 HESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQA 206

Query: 237 SSSEESEERDTKKTKRKKREKKAH 260
                 EER+  K K KK++KK H
Sbjct: 207 KKKRRCEEREQAKEKVKKKKKKQH 230



 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 41/146 (28%), Positives = 67/146 (45%), Gaps = 16/146 (10%)

Query: 147 ESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKR 206
           E +K  ++KK+  K   +   K  +  KKE          E S E   SG     +  +R
Sbjct: 43  EVKKQLENKKTGSKALAEFEEKMNENWKKEL---------EKSREKLLSGNESSSKKRER 93

Query: 207 KKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANN 266
           KKK +KKS +       + S++S SD S+SSS  E EE+   K ++KK+ +   +S ++ 
Sbjct: 94  KKKRKKKSCR-------SSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSST 146

Query: 267 EIQERTNKRTNWKVATDERSAESSED 292
              E  +K +  K    +   E  +D
Sbjct: 147 HESESESKESVKKKKKSKDETEKEKD 172



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 38/176 (21%), Positives = 78/176 (44%), Gaps = 25/176 (14%)

Query: 140 QVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRK 199
           +++ S  +     +S    ++++KKR  K  + S   ++  ++ SSS+  +E    G R+
Sbjct: 72  ELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRR 131

Query: 200 GKQPH---------------------KRKKKSRKKSLK-KPALFLEAESNTSHSDD---S 234
            K+ +                     K+KKKS+ ++ K K    L  +   S+ DD   S
Sbjct: 132 KKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLS 191

Query: 235 ASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESS 290
           + SSSE   E D +  K+++ E++        + +++ +K+ + K      S+  S
Sbjct: 192 SESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKKSGSSHKS 247



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 55/205 (26%), Positives = 87/205 (42%), Gaps = 34/205 (16%)

Query: 35  ELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDE-ESQRYYWRPKNEISGTLEDDFLKAKSW 93
           E++KQ+E+   G+K   L     +M  +   E E  R      NE S    +   + K  
Sbjct: 43  EVKKQLENKKTGSKA--LAEFEEKMNENWKKELEKSREKLLSGNESSSKKRE---RKKKR 97

Query: 94  NKKFYDYEANMPDRWGHSGYKELYPEEFETDSSDQQDITNGKKTSPQVKSSTHES----- 148
            KK     ++       S   +   EE +     ++      K+S   +SSTHES     
Sbjct: 98  KKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSS---QSSTHESESESK 154

Query: 149 ---RKHKKSKKSHKKKQKKRS-HKKQKKSKKEATDITADSSSE--FSEETGASGTR---- 198
              +K KKSK   +K++  RS  KK+KKS  +   ++++SSSE  + E+  A   R    
Sbjct: 155 ESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEE 214

Query: 199 ----------KGKQPHKRKKKSRKK 213
                     K K+ HK+  K +KK
Sbjct: 215 REQAKEKVKKKKKKQHKKHSKKKKK 239



 Score = 35.8 bits (81), Expect = 0.046
 Identities = 43/161 (26%), Positives = 66/161 (40%), Gaps = 19/161 (11%)

Query: 32  KIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEI-------SGTLE 84
           K RE +K+ +     +      S SS   SD  DEE ++   R K +        S T E
Sbjct: 89  KKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHE 148

Query: 85  DDFLKAKSWNKKFYDYEANMPDRWGHS---GYKELYPE------EFETDSSDQQDITNGK 135
            +    +S  KK    +    ++   S     K+ YP+      E  ++S  ++D+   K
Sbjct: 149 SESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKK 208

Query: 136 KTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHK--KQKKSK 174
           K   + +    E  K KK KK HKK  KK+  K     KS+
Sbjct: 209 KRRCEEREQAKEKVK-KKKKKQHKKHSKKKKKKSGSSHKSR 248


>gi|56090620 NFKB activating protein-like [Homo sapiens]
          Length = 402

 Score = 65.5 bits (158), Expect = 5e-11
 Identities = 41/140 (29%), Positives = 69/140 (49%), Gaps = 7/140 (5%)

Query: 101 EANMPDRWGHSGYKELYPEEFETDSSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKK 160
           E   P+ WG S        +  T   D++++T+ K +S     S   S +H+K K S  +
Sbjct: 130 ELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQKSSS-----SDSNSEEHRKKKTSRSR 184

Query: 161 KQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPAL 220
            +KKR +K  K+  ++ +D  +DS+SE    + +   +K  +  K+KKK + K+ KK   
Sbjct: 185 NKKKRKNKSSKRKHRKYSD--SDSNSESDTNSDSDDDKKRVKAKKKKKKKKHKTKKKKNK 242

Query: 221 FLEAESNTSHSDDSASSSSE 240
             + ES+ S   DS    SE
Sbjct: 243 KTKKESSDSSCKDSEEDLSE 262



 Score = 48.9 bits (115), Expect = 5e-06
 Identities = 43/163 (26%), Positives = 76/163 (46%), Gaps = 28/163 (17%)

Query: 142 KSSTHESRKHKKSKK------------SHKKKQKKRSHKKQKKSKKEATDITADSSSEFS 189
           K  +H  R+ K+ ++            S K  Q         + ++E T   + SS   S
Sbjct: 113 KEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQKSSSSDSNS 172

Query: 190 EETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKK 249
           EE     T + +   KRK KS K+  +K   + +++SN   S+   +S S++ ++R   K
Sbjct: 173 EEHRKKKTSRSRNKKKRKNKSSKRKHRK---YSDSDSN---SESDTNSDSDDDKKR--VK 224

Query: 250 TKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSED 292
            K+KK++KK  T       +++ NK+T  K ++D    +S ED
Sbjct: 225 AKKKKKKKKHKT-------KKKKNKKTK-KESSDSSCKDSEED 259



 Score = 33.1 bits (74), Expect = 0.30
 Identities = 28/123 (22%), Positives = 56/123 (45%), Gaps = 22/123 (17%)

Query: 188 FSEETGASGTRKGKQPHKR---KKKSRKKSLKKPALF--------LEAESNTSHSDDS-- 234
           ++EE  ++   + ++ H++   K++ R   L  P ++        L+++ +T   D+   
Sbjct: 101 YAEERQSAEDYEKEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEV 160

Query: 235 ----ASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESS 290
               +SSS   SEE   KKT R + +KK       N+  +R +++ +   +  E    S 
Sbjct: 161 THQKSSSSDSNSEEHRKKKTSRSRNKKKR-----KNKSSKRKHRKYSDSDSNSESDTNSD 215

Query: 291 EDD 293
            DD
Sbjct: 216 SDD 218


>gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]
          Length = 237

 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 61/219 (27%), Positives = 96/219 (43%), Gaps = 32/219 (14%)

Query: 69  QRYYWRPK---NEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHS--GYKELYPEEFET 123
           Q Y  RP+    E+   LE    K K  +K   ++E  M + W      ++E      E+
Sbjct: 21  QDYLNRPRPTWEEVKEQLE----KKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSES 76

Query: 124 DSSDQQDITNGKK----------TSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKS 173
            S  +Q     KK          +S    SS+ +S    K +   +KK+K RSHK  + S
Sbjct: 77  SSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESS 136

Query: 174 KKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDD 233
             E    + DS  +  ++    GT K K      KK +  S  KP L  E+ S + + ++
Sbjct: 137 MSETESDSKDSLKK--KKKSKDGTEKEKDIKGLSKKRKMYSEDKP-LSSESLSESEYIEE 193

Query: 234 SASSSSEESEERD--TKKTKRKK--------REKKAHTS 262
             +   + SEER+  T+KTK+KK        ++KKA +S
Sbjct: 194 VRAKKKKSSEEREKATEKTKKKKKHKKHSKKKKKKAASS 232



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 40/144 (27%), Positives = 67/144 (46%), Gaps = 5/144 (3%)

Query: 147 ESRKHKKSKKS-HKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHK 205
           E  KH++   S  +   KKR  KK++K K      ++ SSS+ S  +  S     KQ  +
Sbjct: 62  ELEKHREKLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKR 121

Query: 206 RKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESE-ERDTKKTKRKKR---EKKAHT 261
           RKKK  +      +   E ES++  S      S + +E E+D K   +K++   E K  +
Sbjct: 122 RKKKKNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLS 181

Query: 262 SVANNEIQERTNKRTNWKVATDER 285
           S + +E +     R   K +++ER
Sbjct: 182 SESLSESEYIEEVRAKKKKSSEER 205



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 39/159 (24%), Positives = 73/159 (45%), Gaps = 9/159 (5%)

Query: 135 KKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGA 194
           + + P ++   +  R   +  K   +K+KK S  K     +E  +       E   E   
Sbjct: 14  QSSGPTIQDYLNRPRPTWEEVKEQLEKKKKGS--KALAEFEEKMNENWKKELEKHREKLL 71

Query: 195 SGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKK 254
           SG+    +  +RKKK +KKS +       + S++S SD S+SSS  E E++   K +RKK
Sbjct: 72  SGSESSSKKRQRKKKEKKKSGRY------SSSSSSSSDSSSSSSDSEDEDKKQGK-RRKK 124

Query: 255 REKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD 293
           ++ ++H S  ++  +  ++ + + K     +     E D
Sbjct: 125 KKNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKEKD 163



 Score = 34.7 bits (78), Expect = 0.10
 Identities = 43/200 (21%), Positives = 76/200 (38%), Gaps = 21/200 (10%)

Query: 25  QEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEISGTLE 84
           ++ ++ WK +ELEK  E    G++     SS  R R     ++S RY        S +  
Sbjct: 53  EKMNENWK-KELEKHREKLLSGSES----SSKKRQRKKKEKKKSGRY------SSSSSSS 101

Query: 85  DDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSSDQQDITNGKKTSPQVKSS 144
            D   + S ++     +     +  +  +K       ET+S  +  +   KK+    K  
Sbjct: 102 SDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKKS----KDG 157

Query: 145 THESRKHKKSKKSHKKKQKKRSHKKQKKSKKE-ATDITADSSSEFSEETGASGTRKGKQP 203
           T + +  K   K  K   + +    +  S+ E   ++ A       E   A+   K K+ 
Sbjct: 158 TEKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKSSEEREKATEKTKKKKK 217

Query: 204 HKR-----KKKSRKKSLKKP 218
           HK+     KKK+   S   P
Sbjct: 218 HKKHSKKKKKKAASSSPDSP 237


>gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]
          Length = 247

 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 61/219 (27%), Positives = 96/219 (43%), Gaps = 32/219 (14%)

Query: 69  QRYYWRPK---NEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHS--GYKELYPEEFET 123
           Q Y  RP+    E+   LE    K K  +K   ++E  M + W      ++E      E+
Sbjct: 31  QDYLNRPRPTWEEVKEQLE----KKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSES 86

Query: 124 DSSDQQDITNGKK----------TSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKS 173
            S  +Q     KK          +S    SS+ +S    K +   +KK+K RSHK  + S
Sbjct: 87  SSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESS 146

Query: 174 KKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDD 233
             E    + DS  +  ++    GT K K      KK +  S  KP L  E+ S + + ++
Sbjct: 147 MSETESDSKDSLKK--KKKSKDGTEKEKDIKGLSKKRKMYSEDKP-LSSESLSESEYIEE 203

Query: 234 SASSSSEESEERD--TKKTKRKK--------REKKAHTS 262
             +   + SEER+  T+KTK+KK        ++KKA +S
Sbjct: 204 VRAKKKKSSEEREKATEKTKKKKKHKKHSKKKKKKAASS 242



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 40/144 (27%), Positives = 67/144 (46%), Gaps = 5/144 (3%)

Query: 147 ESRKHKKSKKS-HKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHK 205
           E  KH++   S  +   KKR  KK++K K      ++ SSS+ S  +  S     KQ  +
Sbjct: 72  ELEKHREKLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKR 131

Query: 206 RKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESE-ERDTKKTKRKKR---EKKAHT 261
           RKKK  +      +   E ES++  S      S + +E E+D K   +K++   E K  +
Sbjct: 132 RKKKKNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLS 191

Query: 262 SVANNEIQERTNKRTNWKVATDER 285
           S + +E +     R   K +++ER
Sbjct: 192 SESLSESEYIEEVRAKKKKSSEER 215



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 39/159 (24%), Positives = 73/159 (45%), Gaps = 9/159 (5%)

Query: 135 KKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGA 194
           + + P ++   +  R   +  K   +K+KK S  K     +E  +       E   E   
Sbjct: 24  QSSGPTIQDYLNRPRPTWEEVKEQLEKKKKGS--KALAEFEEKMNENWKKELEKHREKLL 81

Query: 195 SGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKK 254
           SG+    +  +RKKK +KKS +       + S++S SD S+SSS  E E++   K +RKK
Sbjct: 82  SGSESSSKKRQRKKKEKKKSGRY------SSSSSSSSDSSSSSSDSEDEDKKQGK-RRKK 134

Query: 255 REKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD 293
           ++ ++H S  ++  +  ++ + + K     +     E D
Sbjct: 135 KKNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKEKD 173



 Score = 34.7 bits (78), Expect = 0.10
 Identities = 43/200 (21%), Positives = 76/200 (38%), Gaps = 21/200 (10%)

Query: 25  QEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEISGTLE 84
           ++ ++ WK +ELEK  E    G++     SS  R R     ++S RY        S +  
Sbjct: 63  EKMNENWK-KELEKHREKLLSGSES----SSKKRQRKKKEKKKSGRY------SSSSSSS 111

Query: 85  DDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSSDQQDITNGKKTSPQVKSS 144
            D   + S ++     +     +  +  +K       ET+S  +  +   KK+    K  
Sbjct: 112 SDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKKS----KDG 167

Query: 145 THESRKHKKSKKSHKKKQKKRSHKKQKKSKKE-ATDITADSSSEFSEETGASGTRKGKQP 203
           T + +  K   K  K   + +    +  S+ E   ++ A       E   A+   K K+ 
Sbjct: 168 TEKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKSSEEREKATEKTKKKKK 227

Query: 204 HKR-----KKKSRKKSLKKP 218
           HK+     KKK+   S   P
Sbjct: 228 HKKHSKKKKKKAASSSPDSP 247


>gi|4557509 cylicin 2 [Homo sapiens]
          Length = 348

 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 45/150 (30%), Positives = 65/150 (43%), Gaps = 20/150 (13%)

Query: 123 TDSSDQQ-----DITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEA 177
           T+S D++     D    KK S + K S  ES    + +K   +K  K+  K  KK K  A
Sbjct: 176 TESEDEKGGAKKDNKKDKKDSNKGKDSATES----EGEKGGTEKDSKKGKKDSKKGKDSA 231

Query: 178 TDITADSSSEFSEETGASGTRKGKQPHKRKK-----KSRKKSLKKPALFLEAESNTSHSD 232
            ++ A  + E  +E G     KG +    KK     K  KK  KKP+      S  S S 
Sbjct: 232 IELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPS------STDSDSK 285

Query: 233 DSASSSSEESEERDTKKTKRKKREKKAHTS 262
           D     S++   +D KK  +K  EK++  S
Sbjct: 286 DDVKKESKKDATKDAKKVAKKDTEKESADS 315



 Score = 55.5 bits (132), Expect = 6e-08
 Identities = 44/181 (24%), Positives = 88/181 (48%), Gaps = 14/181 (7%)

Query: 124 DSSDQQDITNGKKTSPQVKSSTHESRK--HKKSKKSHKKKQKKRSHKKQKKSKKEATDIT 181
           DS   +DI  GK+     K  + + +K   K    + + + +K   KK  K  K+ ++  
Sbjct: 140 DSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKG 199

Query: 182 ADSSSEFSEETGASGTRK-GKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSE 240
            DS++E   E G  GT K  K+  K  KK +  +++  A+  + + +     D+      
Sbjct: 200 KDSATESEGEKG--GTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDES 257

Query: 241 ESEERDTKKTKRKKREKKAHTSV---ANNEIQERTNK---RTNWKVA---TDERSAESSE 291
           +  ++D K+ K+ K++KK  +S    + +++++ + K   +   KVA   T++ SA+S +
Sbjct: 258 KDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKK 317

Query: 292 D 292
           D
Sbjct: 318 D 318



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 59/251 (23%), Positives = 100/251 (39%), Gaps = 40/251 (15%)

Query: 32  KIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEISGTLEDDFLKAK 91
           K  E+ K+ ED    T +K    S S ++    D +  +   + K E     +D   K K
Sbjct: 110 KAAEIGKKGEDK---TTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDS-KKGK 165

Query: 92  SWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSSDQQDITNGKKTSPQVKSSTHESRKH 151
              +K  D      D  G  G K+        +  D++D   GK ++ + +     + K 
Sbjct: 166 KDAEKGKDSATESEDEKG--GAKK-------DNKKDKKDSNKGKDSATESEGEKGGTEKD 216

Query: 152 KKSKKSHKKKQK---------KRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQ 202
            K  K   KK K         K   KK +  KK+A     D S +  ++  A   +KGK+
Sbjct: 217 SKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDAN--KGDESKDAKKD--AKEIKKGKK 272

Query: 203 PHKR------------KKKSRKKSLK--KPALFLEAESNTSHSDDSASSSSEESEERDTK 248
             K+            KK+S+K + K  K     + E  ++ S   A  ++++  ++D K
Sbjct: 273 DKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAK 332

Query: 249 KTKRKKREKKA 259
           K  +K  +K A
Sbjct: 333 KNAKKDEKKDA 343



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 48/245 (19%), Positives = 100/245 (40%), Gaps = 34/245 (13%)

Query: 18  TDAHNKIQE-ESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPK 76
           TD+ +++++ + D  K +++EK  E+     K        +    D   E         +
Sbjct: 128 TDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATES--------E 179

Query: 77  NEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSSDQQDITNGKK 136
           +E  G  +D+    K  NK     + +  +  G  G  E      +     ++D   GK 
Sbjct: 180 DEKGGAKKDNKKDKKDSNKG----KDSATESEGEKGGTE------KDSKKGKKDSKKGKD 229

Query: 137 TSPQVKSSTHESRKHKKSKKSHKK-------KQKKRSHKKQKKSKKEATDITADSSSEFS 189
           ++ ++++   + +K +  KK   K       K+  +  KK KK KK+ +   +DS  +  
Sbjct: 230 SAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVK 289

Query: 190 EETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKK 249
           +E+    T+  K+  K+  +      KK A          ++   A   ++++ ++D KK
Sbjct: 290 KESKKDATKDAKKVAKKDTEKESADSKKDA--------KKNAKKDAKKDAKKNAKKDEKK 341

Query: 250 TKRKK 254
             +KK
Sbjct: 342 DAKKK 346


>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 245

 Score = 55.5 bits (132), Expect = 6e-08
 Identities = 35/173 (20%), Positives = 76/173 (43%), Gaps = 3/173 (1%)

Query: 122 ETDSSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDIT 181
           E +S  +++    +K   + +      R  K+ K   KK++++R  ++++K  KE  +  
Sbjct: 54  ERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKE 113

Query: 182 ADSSSEFSEE--TGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSS 239
                E  E   T   G  + ++  +++++ +++  KK     E E       +      
Sbjct: 114 KRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGE 173

Query: 240 EESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSED 292
           +E E ++ ++ +RKKRE+         E +ER  ++   K   +ER  E  +D
Sbjct: 174 KEEERKEKERKERKKRERNRKERKKERERKERRERKKERK-KKEERKKERQKD 225



 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 52/248 (20%), Positives = 99/248 (39%), Gaps = 53/248 (21%)

Query: 32  KIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEISGTLEDDFLKAK 91
           +IRE E+++E    G K +                ES+R   R + E          K K
Sbjct: 37  EIREREREIETRKEGKKER----------------ESERKKERRERE----------KRK 70

Query: 92  SWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSSDQQDITNGKKTSPQVKSSTHESRKH 151
              +K    E    ++ G    +E    E +    ++++    +K   + K      R  
Sbjct: 71  REREKERKRERGKKEKKGERKKEE---RERKKRRREKENKEGEEKEKRKKKEKKERGRTS 127

Query: 152 KKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSR 211
           K+ K+  +K+++KR  +K+++ KKE  +       E  E       + G++  +RK+K R
Sbjct: 128 KEGKERERKEERKREERKERERKKEERE----KERERKERKKRERKQVGEKEEERKEKER 183

Query: 212 KKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQER 271
           K+  K+             +        E  E R+ KK ++KK E+K          + +
Sbjct: 184 KERKKR-----------ERNRKERKKERERKERRERKKERKKKEERKK---------ERQ 223

Query: 272 TNKRTNWK 279
            +++TNW+
Sbjct: 224 KDRQTNWR 231



 Score = 52.0 bits (123), Expect = 6e-07
 Identities = 33/155 (21%), Positives = 67/155 (43%), Gaps = 4/155 (2%)

Query: 140 QVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKK---SKKEATDITADSSSEFSEETGASG 196
           + +    + R+ ++ K+  +++++KR  +K++K    KKE          E  +      
Sbjct: 46  ETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKE 105

Query: 197 TRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKRE 256
            ++G++  KRKKK +K+  +      E E       +       + EER+ K+ +RK+R+
Sbjct: 106 NKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEERE-KERERKERK 164

Query: 257 KKAHTSVANNEIQERTNKRTNWKVATDERSAESSE 291
           K+    V   E + +  +R   K     R     E
Sbjct: 165 KRERKQVGEKEEERKEKERKERKKRERNRKERKKE 199



 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 34/168 (20%), Positives = 75/168 (44%), Gaps = 5/168 (2%)

Query: 128 QQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSH-KKQKKSKKEATDITADSSS 186
           +++I   K+   + +S   + R+ ++ +K  ++K++KR   KK+KK +++  +   +   
Sbjct: 42  EREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE--RERKK 99

Query: 187 EFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERD 246
              E+    G  K K+  K KK+  + S +      + E       +      E  +ER+
Sbjct: 100 RRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERE 159

Query: 247 TKKTKRKKREK--KAHTSVANNEIQERTNKRTNWKVATDERSAESSED 292
            K+ K+++R++  +        E +ER  +  N K    ER  +   +
Sbjct: 160 RKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRE 207



 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 33/175 (18%), Positives = 70/175 (40%), Gaps = 2/175 (1%)

Query: 119 EEFETDSSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEAT 178
           E  E +   ++     K+   + +      ++ ++ KK  ++K+ K   +K+K+ KKE  
Sbjct: 62  ERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKK 121

Query: 179 DITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSS 238
           +    S      E      R+ ++  +RKK+ R+K  ++              ++     
Sbjct: 122 ERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKE- 180

Query: 239 SEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD 293
            +E +ER  ++  RK+R+K+          +ER  K    K    +R     E +
Sbjct: 181 -KERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKE 234



 Score = 48.9 bits (115), Expect = 5e-06
 Identities = 40/159 (25%), Positives = 73/159 (45%), Gaps = 10/159 (6%)

Query: 137 TSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASG 196
           T P  +S   E  +  +++K  KK+++    K++++ +K   +   +   E  ++    G
Sbjct: 30  TQPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKE-KKG 88

Query: 197 TRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEER----DTKKTKR 252
            RK K+  +RKK+ R+K  K+     E E            +S+E +ER    + K+ +R
Sbjct: 89  ERK-KEERERKKRRREKENKEGE---EKEKRKKKEKKERGRTSKEGKERERKEERKREER 144

Query: 253 KKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSE 291
           K+RE+K        E +ER  KR   +V   E   +  E
Sbjct: 145 KERERKKEEREKERERKER-KKRERKQVGEKEEERKEKE 182



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 30/147 (20%), Positives = 63/147 (42%), Gaps = 20/147 (13%)

Query: 147 ESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKR 206
           ES + K+ ++  K+K+++   +K+++ KKE          E  +       ++G++  KR
Sbjct: 56  ESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKR 115

Query: 207 KKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANN 266
           KKK +K          E    +    +       + EER  ++ K+++REK+        
Sbjct: 116 KKKEKK----------ERGRTSKEGKERERKEERKREERKERERKKEEREKE-------- 157

Query: 267 EIQERTNKRTNWKVATDERSAESSEDD 293
             +ER  ++   +    E+  E  E +
Sbjct: 158 --RERKERKKRERKQVGEKEEERKEKE 182



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 37/200 (18%), Positives = 79/200 (39%), Gaps = 5/200 (2%)

Query: 18  TDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKN 77
           T    K + ES+  K R  E++     R  +RK       +      +E  ++   R K 
Sbjct: 47  TRKEGKKERESERKKERR-EREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKE 105

Query: 78  EISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSSDQQDITNGKKT 137
              G  ++   K +   +     E    +R      +E    E + +  +++     +K 
Sbjct: 106 NKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKK 165

Query: 138 SPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGT 197
             + +    E  + +K +K  KK+++ R  +K+++ +KE  +   +   +   +      
Sbjct: 166 RERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKD 225

Query: 198 R----KGKQPHKRKKKSRKK 213
           R    + K+  KR++K RKK
Sbjct: 226 RQTNWREKERGKRERKERKK 245


>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 275

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 37/176 (21%), Positives = 74/176 (42%), Gaps = 1/176 (0%)

Query: 114 KELYPEEFETDSSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKS 173
           +E    E E +   ++     KK   + +    E ++ ++ K+  ++++K+R  +K++K 
Sbjct: 43  REKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKK 102

Query: 174 KKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDD 233
           K+E          +  E        K ++  KRKK+ +KK  K+     E          
Sbjct: 103 KRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKK 162

Query: 234 SASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAES 289
                 E+  ER+ +K ++K+RE+K          +ER  K+   K    +R  +S
Sbjct: 163 RKKEEREKKRERN-RKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDS 217



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 38/147 (25%), Positives = 62/147 (42%), Gaps = 24/147 (16%)

Query: 147 ESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKR 206
           E RK KK KK  ++KQ+ R  +K+KK +KE                     R+ KQ  +R
Sbjct: 93  ERRKRKKEKKKRERKQRGRRERKKKKERKERE-------------------RENKQRRER 133

Query: 207 KKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTK-RKKREKKAHTSVAN 265
           K+K R+K  ++     E +               + EER+ K+ + RK+R+K+       
Sbjct: 134 KRKKRRKKKRRK----ERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERR 189

Query: 266 NEIQERTNKRTNWKVATDERSAESSED 292
              +ER  +R   K    +R  +   D
Sbjct: 190 ERKKERKKERRKKKERKKDRKTDRQTD 216



 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 33/158 (20%), Positives = 69/158 (43%), Gaps = 6/158 (3%)

Query: 136 KTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGAS 195
           K   Q +S   + R+ ++ +K  ++K++KR   K++K K++  +   +   +  E     
Sbjct: 27  KPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQR 86

Query: 196 GTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKR 255
             R+ K+  KRKK+ +K+  K+               +      E  + R+ K+ KR+K+
Sbjct: 87  KERREKERRKRKKEKKKRERKQ-----RGRRERKKKKERKERERENKQRRERKRKKRRKK 141

Query: 256 EKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD 293
           +++        E  +R  KR   K    E+  E +  +
Sbjct: 142 KRRKERK-REKERGKRERKRKKRKKEEREKKRERNRKE 178



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 39/193 (20%), Positives = 75/193 (38%), Gaps = 14/193 (7%)

Query: 25  QEESDMWKIR-ELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEISGTL 83
           Q ES+  K R E EK+  +  +  KR+       + +     +E +R     + +     
Sbjct: 31  QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90

Query: 84  EDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSSDQQDITNGKKTSPQVKS 143
           E +  K K   KK    +    +R      KE   E  +     ++     K+   + + 
Sbjct: 91  EKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKRE 150

Query: 144 STHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQP 203
                R+ K+ K+  ++++KKR   ++++ K+              E       +K ++ 
Sbjct: 151 KERGKRERKRKKRKKEEREKKRERNRKERKKER-------------ERKERRERKKERKK 197

Query: 204 HKRKKKSRKKSLK 216
            +RKKK RKK  K
Sbjct: 198 ERRKKKERKKDRK 210



 Score = 35.0 bits (79), Expect = 0.078
 Identities = 28/145 (19%), Positives = 59/145 (40%), Gaps = 4/145 (2%)

Query: 32  KIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEISGTLEDDFLKAK 91
           K +E EKQ ++     +RK       R R      E ++   R + E       +  + K
Sbjct: 78  KRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKK 137

Query: 92  SWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSSDQQDITNGKKTSPQVKSSTHESRKH 151
              KK         +R    G +E   ++ + +  +++   N K+   + +      RK 
Sbjct: 138 RRKKKRRKERKREKER----GKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKK 193

Query: 152 KKSKKSHKKKQKKRSHKKQKKSKKE 176
           ++ K+  KKK++K+  K  +++  +
Sbjct: 194 ERKKERRKKKERKKDRKTDRQTDSQ 218



 Score = 30.8 bits (68), Expect = 1.5
 Identities = 21/115 (18%), Positives = 48/115 (41%), Gaps = 1/115 (0%)

Query: 178 TDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASS 237
           T++   S S  S+      + + K+  +R+K+ R++  ++     + E       +    
Sbjct: 15  TELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKE 74

Query: 238 SSEESEERD-TKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSE 291
              + +ER+  +K +R+K  +K        E ++R  +    K    ER  E+ +
Sbjct: 75  RERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQ 129


>gi|151301228 formin binding protein 3 [Homo sapiens]
          Length = 930

 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 39/149 (26%), Positives = 68/149 (45%), Gaps = 20/149 (13%)

Query: 146 HESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSS----EFSEETGA---SGTR 198
           HE + H    K H KK KK  H+K+ +S+  +     DS S    + SE   A   S + 
Sbjct: 775 HECQHHHSKNKKHSKKSKKH-HRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSA 833

Query: 199 KGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKK 258
           + ++ +K+ KK +KKS K+            H  DS  S +E  +++  K  + +K   +
Sbjct: 834 ESERSYKKSKKHKKKSKKR-----------RHKSDSPESDAEREKDKKEKDRESEKDRTR 882

Query: 259 AHTSVANNEIQERTNKRT-NWKVATDERS 286
             +   +   +++T K + NW  +  E S
Sbjct: 883 QRSESKHKSPKKKTGKDSGNWDTSGSELS 911



 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 37/135 (27%), Positives = 62/135 (45%), Gaps = 16/135 (11%)

Query: 147 ESRKH-KKSKKSHKKKQKKRS---------HKKQKKSKKEATDITADSSSEFSEETGASG 196
           +++KH KKSKK H+K+ + RS         H K+K+ + E+   +  SSS  SE +    
Sbjct: 783 KNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESERS---- 838

Query: 197 TRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSD-DSASSSSEESEERDTKKTKRKKR 255
             K  + HK+K K R+     P    E E +    D +S    + +  E   K  K+K  
Sbjct: 839 -YKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEKDRTRQRSESKHKSPKKKTG 897

Query: 256 EKKAHTSVANNEIQE 270
           +   +   + +E+ E
Sbjct: 898 KDSGNWDTSGSELSE 912



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 58/245 (23%), Positives = 101/245 (41%), Gaps = 39/245 (15%)

Query: 20  AHNKIQEESDMWKIRELEKQMEDAYRGTKRK------MLPSSSSRMRSDGFDEESQRYYW 73
           A N + E+++    RE E++ E+A R  KRK      ML  ++  +  D   E+ +  + 
Sbjct: 693 AFNSLLEKAEA---REREREKEEA-RKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFV 748

Query: 74  RPKNEISGTLED-------DFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSS 126
           +       TLE        DF+       + +  +     +     +++       +DS 
Sbjct: 749 KEPAFEDITLESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSD 808

Query: 127 DQQDITNGKKTSPQVKSSTHES------RKHKKSKKSHKKKQKKRSHKKQKKSKKEATDI 180
           D    +  K+   + +S++  S      R +KKSKK HKKK KKR H      K ++ + 
Sbjct: 809 DDDSHSKKKRQRSESRSASEHSSSAESERSYKKSKK-HKKKSKKRRH------KSDSPES 861

Query: 181 TADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSE 240
            A+   +  E+   S   + +Q  + K KS KK   K         ++ + D S S  SE
Sbjct: 862 DAEREKDKKEKDRESEKDRTRQRSESKHKSPKKKTGK---------DSGNWDTSGSELSE 912

Query: 241 ESEER 245
              E+
Sbjct: 913 GELEK 917



 Score = 33.5 bits (75), Expect = 0.23
 Identities = 38/173 (21%), Positives = 66/173 (38%), Gaps = 38/173 (21%)

Query: 147 ESRKHKKSKKSHKKKQKK----RSHKKQKKSKKEATDITADSSSEFSEETG-----ASGT 197
           E+R+ ++ K+  +K ++K    +S  KQ     E   +  D    F +E           
Sbjct: 702 EAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITLESE 761

Query: 198 RKG-------------KQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEE 244
           RK              +  H + KK  KKS K             H   S S S  +S++
Sbjct: 762 RKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKH------------HRKRSRSRSGSDSDD 809

Query: 245 RDTKKTKRKKREKKA----HTSVANNEIQERTNKRTNWKVATDERSAESSEDD 293
            D+   K+++R +      H+S A +E   + +K+   K       ++S E D
Sbjct: 810 DDSHSKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESD 862



 Score = 33.5 bits (75), Expect = 0.23
 Identities = 20/91 (21%), Positives = 37/91 (40%)

Query: 202 QPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHT 261
           Q H  K K   K  KK         + S SDD  S S ++ +  +++         ++  
Sbjct: 778 QHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESER 837

Query: 262 SVANNEIQERTNKRTNWKVATDERSAESSED 292
           S   ++  ++ +K+   K  + E  AE  +D
Sbjct: 838 SYKKSKKHKKKSKKRRHKSDSPESDAEREKD 868


>gi|40068059 CBF1 interacting corepressor [Homo sapiens]
          Length = 450

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 40/165 (24%), Positives = 75/165 (45%), Gaps = 4/165 (2%)

Query: 129 QDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEF 188
           + +T  +K     K    E +K KK +K  K ++ +  HKK K S   ++  ++ SS+E 
Sbjct: 214 KSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTET 273

Query: 189 SEETGAS-GTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDT 247
           SE +  S    K K+  ++K+K  K S    +   E + +         SSS  + E+  
Sbjct: 274 SESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAK 333

Query: 248 KKTKRKKREKKAHTSV---ANNEIQERTNKRTNWKVATDERSAES 289
           +K +  K E     S    ++++ + RT+K +  K  ++ +   S
Sbjct: 334 EKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSS 378



 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 30/97 (30%), Positives = 48/97 (49%), Gaps = 2/97 (2%)

Query: 198 RKGKQPHKRKK--KSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKR 255
           +K K+  K+KK  KSR K  K  +    + S++S S    S SS ESE  + +K  ++K+
Sbjct: 234 KKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKK 293

Query: 256 EKKAHTSVANNEIQERTNKRTNWKVATDERSAESSED 292
            KK   S  NN   E  +K    K+  +  S+  + +
Sbjct: 294 RKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNRE 330



 Score = 42.0 bits (97), Expect = 6e-04
 Identities = 37/177 (20%), Positives = 69/177 (38%), Gaps = 32/177 (18%)

Query: 123 TDSSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKR--------SHKKQKKSK 174
           ++SS + +  N +K   + K   ++   H  S    K K KKR        SH  ++K+K
Sbjct: 274 SESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAK 333

Query: 175 KEATDITADSSSEFS------------------EETGASGTRKGKQPHKRKKKSRKKSLK 216
           ++   +  +SS E S                  E+ G+       + H R+++SR+   +
Sbjct: 334 EKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREERSRRSRSR 393

Query: 217 KPALFLEAESNTSHSDDSASSSSEESEER----DTKKTKRKKREKK--AHTSVANNE 267
            P  + + E+      +     S  ++ R    D  + ++  RE     HT V   E
Sbjct: 394 SPGSYKQRETRKRAQRNPGEEQSRRNDSRSHGTDLYRGEKMYREHPGGTHTKVTQRE 450


>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 123

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 34/125 (27%), Positives = 56/125 (44%), Gaps = 15/125 (12%)

Query: 168 KKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAE-- 225
           KK+KK KKE  +   + + E  EE    G RK K+  KRK+K +KK  K+     E E  
Sbjct: 1   KKKKKKKKETEE--TEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEE 58

Query: 226 -----------SNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNK 274
                            ++      EE EE + ++ +R+K++KK        E +++  +
Sbjct: 59  EKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRR 118

Query: 275 RTNWK 279
           +T  K
Sbjct: 119 KTKKK 123



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 32/141 (22%), Positives = 63/141 (44%), Gaps = 20/141 (14%)

Query: 135 KKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGA 194
           KK   +    T E+ + ++ ++   K+++KR  K+++K KK+ T  T             
Sbjct: 3   KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETE------------ 50

Query: 195 SGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKK 254
              RK K+  ++K+K ++K  K      E E      ++      EE +E   ++ K+KK
Sbjct: 51  --KRKEKEEEEKKRKRKRKKKK------EEEEREEEEEEEEEEKEEEEKEEGRRRKKKKK 102

Query: 255 REKKAHTSVANNEIQERTNKR 275
           R +K        + + +T K+
Sbjct: 103 RRRKEEEEEKKKKRRRKTKKK 123



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 35/140 (25%), Positives = 66/140 (47%), Gaps = 28/140 (20%)

Query: 119 EEFETDSSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEAT 178
           E  ET+ +++++   GK+   + K    E  K KK+K++ K+K+K+   KK+K+ +K+  
Sbjct: 12  ETEETEETEEEEEKEGKRKEKR-KEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKK 70

Query: 179 DITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSS 238
           +   +   E  EE       + K+  +R+KK +K+  K+                     
Sbjct: 71  E--EEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKE--------------------- 107

Query: 239 SEESEERDTKKTKRKKREKK 258
               EE + KK +R+K +KK
Sbjct: 108 ----EEEEKKKKRRRKTKKK 123



 Score = 34.3 bits (77), Expect = 0.13
 Identities = 17/88 (19%), Positives = 40/88 (45%), Gaps = 5/88 (5%)

Query: 206 RKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVAN 265
           +KKK +KK  ++       E+  +  ++      +E  +   K+ ++KK+ K+       
Sbjct: 1   KKKKKKKKETEETE-----ETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEK 55

Query: 266 NEIQERTNKRTNWKVATDERSAESSEDD 293
            E +++  ++   K   +ER  E  E++
Sbjct: 56  EEEEKKRKRKRKKKKEEEEREEEEEEEE 83


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 49/177 (27%), Positives = 78/177 (44%), Gaps = 9/177 (5%)

Query: 120 EFETDSSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATD 179
           E  +DSSD     + +  S    ++ + S K   + KS   K      +     +K  T 
Sbjct: 360 ESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTR 419

Query: 180 ITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEA----ESNTSHSDDSA 235
               SSSE  EE+ +S   K K   K    ++ K+  K AL L A    + +   S DS 
Sbjct: 420 KADSSSSE--EESSSSEEEKTK---KMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSD 474

Query: 236 SSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSED 292
           SSSSEE EE+ +K   +KK +K A  +  +     +  K  +   ++ + S+E  E+
Sbjct: 475 SSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEE 531



 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 69/271 (25%), Positives = 106/271 (39%), Gaps = 45/271 (16%)

Query: 50  KMLPSSSSRMRSDGFDEESQRYYWRPKNEISGTLEDDFLKAKSWNKKFY----DYEANMP 105
           K   SSSS   SD  DEE Q+     K  +   ++     AK+  KK      D +++  
Sbjct: 122 KASESSSSEESSDDDDEEDQK-----KQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSE 176

Query: 106 DRWGHSGYKELYPEEFETDSSDQQD-------ITNGKKTSPQVKSSTHESRKHKKSKKSH 158
           D    +   ++ P   +  +            I NGK  S    SS+  S    + +K+ 
Sbjct: 177 DEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKA- 235

Query: 159 KKKQKKRSHKKQKKSK---KEATDITADSSSEFSEETGASGTRKGKQPHKRKK------- 208
               KK   KKQ  +K   K AT  T  SSS  SE++ +    + K+P K K        
Sbjct: 236 AATPKKTVPKKQVVAKAPVKAATTPTRKSSS--SEDSSSDEEEEQKKPMKNKPGPYSSVP 293

Query: 209 ----KSRKKSL--KKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTS 262
                  KKSL  + P   +E +     S+DS+  S   SEE     TK          +
Sbjct: 294 PPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTK----------A 343

Query: 263 VANNEIQERTNKRTNWKVATDERSAESSEDD 293
           V +    +    +   + ++D   ++SSEDD
Sbjct: 344 VVSKATTKPPPAKKAAESSSDSSDSDSSEDD 374



 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 41/174 (23%), Positives = 76/174 (43%), Gaps = 15/174 (8%)

Query: 128 QQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSE 187
           QQ + + + +S +  SS+ E +K        K   K    KK  +S  +++D  +DSS +
Sbjct: 316 QQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSD--SDSSED 373

Query: 188 FSEETGASGTRKG---------KQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSS 238
               +  +GT K          K P  +   + K+ +      L  ++++S S++ +SSS
Sbjct: 374 DEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSS 433

Query: 239 SEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSED 292
            EE  ++    TK K   K A +  A    Q   +  ++    +D  S+E  E+
Sbjct: 434 EEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSD----SDSSSSEEEEE 483



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 44/152 (28%), Positives = 68/152 (44%), Gaps = 17/152 (11%)

Query: 137 TSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKK--QKKSKKEATDITADSSSEFSEETGA 194
           +S + +SS+ E  K KK   + K K   ++      K++ + + D ++DS S  SEE   
Sbjct: 424 SSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEE 483

Query: 195 SGTRKGKQPHKRKKKSRKKSLKKPALFLEAE---SNTSHSDDSASSSSEESEERDTKKTK 251
             T K     K +K +   +  KPA   + +   SN+S SDD   SS EE E+   K + 
Sbjct: 484 K-TSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDD---SSEEEEEKLKGKGSP 539

Query: 252 RKKREKKAHTS--------VANNEIQERTNKR 275
           R +  K   TS         A N  +E   K+
Sbjct: 540 RPQAPKANGTSALTAQNGKAAKNSEEEEEEKK 571



 Score = 38.1 bits (87), Expect = 0.009
 Identities = 33/123 (26%), Positives = 54/123 (43%), Gaps = 21/123 (17%)

Query: 171 KKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSH 230
           KK+KK+A+   ++ SSE  EE      +K   P KR      K+  K             
Sbjct: 76  KKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKA------------ 123

Query: 231 SDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESS 290
              S SSSSEES + D ++ ++K+  +K        + Q +  K    K  + +  ++SS
Sbjct: 124 ---SESSSSEESSDDDDEEDQKKQPVQK------GVKPQAKAAKAPPKKAKSSDSDSDSS 174

Query: 291 EDD 293
            +D
Sbjct: 175 SED 177



 Score = 36.6 bits (83), Expect = 0.027
 Identities = 31/134 (23%), Positives = 56/134 (41%), Gaps = 4/134 (2%)

Query: 135 KKTSPQVKSSTHESRKHKKSKKSHKKKQKK----RSHKKQKKSKKEATDITADSSSEFSE 190
           + +S    SS+ E  + K SK + KKK +K     +  K   +KK   + +  SSS+ S 
Sbjct: 467 RDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSS 526

Query: 191 ETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKT 250
           E      +    P  +  K+   S         A+++    ++   ++   S+    KK 
Sbjct: 527 EEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKR 586

Query: 251 KRKKREKKAHTSVA 264
           K+ +  K+A T  A
Sbjct: 587 KQNEAAKEAETPQA 600



 Score = 34.7 bits (78), Expect = 0.10
 Identities = 50/208 (24%), Positives = 79/208 (37%), Gaps = 30/208 (14%)

Query: 54  SSSSRMRSDGFDEESQRYYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGY 113
           SSSS   S   D E ++    PK     T+    + AK+  K      A  P R   S  
Sbjct: 218 SSSSSSSSSSDDSEEEKAAATPKK----TVPKKQVVAKAPVKA-----ATTPTRKSSSS- 267

Query: 114 KELYPEEFETDSSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKS 173
                E+  +D  ++Q      K  P        +   KKS  +   K+       +K+ 
Sbjct: 268 -----EDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAV-----EKQQ 317

Query: 174 KKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDD 233
             E+++ ++D S   SEE         K+P  +   S  K+  KP    +A  ++S S D
Sbjct: 318 PVESSEDSSDESDSSSEEE--------KKPPTKAVVS--KATTKPPPAKKAAESSSDSSD 367

Query: 234 SASSSSEESEERDTKKTKRKKREKKAHT 261
           S SS  +E+  +    TK    +    T
Sbjct: 368 SDSSEDDEAPSKPAGTTKNSSNKPAVTT 395


>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
           sapiens]
          Length = 434

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 33/149 (22%), Positives = 64/149 (42%), Gaps = 2/149 (1%)

Query: 142 KSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGK 201
           + S +E RKH+   +S + ++ +   K  KK K E  +    SS +  E   +S    G+
Sbjct: 52  RKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSS--ENGE 109

Query: 202 QPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHT 261
             HKRK++   +             + S S +   S S   E + ++   R++++ ++ +
Sbjct: 110 DRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRS 169

Query: 262 SVANNEIQERTNKRTNWKVATDERSAESS 290
                 I+ R+  R+  +  T  RS   S
Sbjct: 170 RERKRRIRSRSRSRSRHRHRTRSRSRTRS 198



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 42/171 (24%), Positives = 74/171 (43%), Gaps = 24/171 (14%)

Query: 125 SSDQQDITNGKKTSPQ--VKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITA 182
           S  ++D    +KTSP    K    E     ++ K H  + + RS ++++KS  E      
Sbjct: 4   SDTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEG----- 58

Query: 183 DSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSAS---SSS 239
                  +    S +++G++ H+ K KS KK         E  ++  HS D      +SS
Sbjct: 59  ------RKHRSRSRSKEGRR-HESKDKSSKKHKS------EEHNDKEHSSDKGRERLNSS 105

Query: 240 EESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESS 290
           E  E+R  K+ +RK    ++H+   + E + R+  R   K  +  R  + S
Sbjct: 106 ENGEDRH-KRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKS 155



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 32/134 (23%), Positives = 56/134 (41%), Gaps = 14/134 (10%)

Query: 136 KTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGAS 195
           K+S + KS  H  ++H   K   +    +    + K+ +++++   + S S   E    S
Sbjct: 78  KSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRS 137

Query: 196 GTRKGKQPHKR-------------KKKSRKKSL-KKPALFLEAESNTSHSDDSASSSSEE 241
            +R+ K+   R             +KKSR +S  +K  +   + S + H   + S S   
Sbjct: 138 RSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTR 197

Query: 242 SEERDTKKTKRKKR 255
           S  RD KK   K R
Sbjct: 198 SRSRDRKKRIEKPR 211



 Score = 42.0 bits (97), Expect = 6e-04
 Identities = 48/229 (20%), Positives = 97/229 (42%), Gaps = 21/229 (9%)

Query: 55  SSSRMRSDGFDEESQRYYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYK 114
           S SR R    D E +++  R +++     E    K KS +KK    E N  +     G +
Sbjct: 45  SRSRERKRKSDNEGRKHRSRSRSKEGRRHES---KDKS-SKKHKSEEHNDKEHSSDKGRE 100

Query: 115 ELYPEEFETDSSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSK 174
            L   E   D   +++    +K+S     S   SR+ +   +S ++K+ +   +++KKS+
Sbjct: 101 RLNSSENGEDRHKRKE----RKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSR 156

Query: 175 KEATDITADSSSEFSEETGASGTRKGKQPHKRKKKS----------RKKSLKKPALFLEA 224
             + +     S     +       + +  H+ + +S          RKK ++KP  F  +
Sbjct: 157 SRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRS 216

Query: 225 ESNT-SHSDDSASSSSEESEERDTKKTKRKKR--EKKAHTSVANNEIQE 270
            S T S       +++ +++E   ++ +R K+  E++    V   + QE
Sbjct: 217 LSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQE 265


>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
          Length = 754

 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 58/286 (20%), Positives = 124/286 (43%), Gaps = 29/286 (10%)

Query: 21  HNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEIS 80
           H  + E  +  +  E EK+++D    +K + +     R  S+  D+   +   R K++  
Sbjct: 409 HRNVSESPN--RKNEKEKKVKDHKSNSKERDI-----RRNSEKDDKYKNKVKKRAKSKSR 461

Query: 81  GTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSSDQ-QDITNGKKTSP 139
              ++     +  +K   + E  M  R     ++ +  +E ++DS  + Q+ +  K+ S 
Sbjct: 462 SKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSK 521

Query: 140 QVKSSTHESRKHKKSKKSHKKKQK----------KRSHKKQKKSKKEATDITADSSSEFS 189
           Q++S ++E   H KSK+  ++ Q           K S+  + + +  + D +    S   
Sbjct: 522 QLESKSNE-HDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTH 580

Query: 190 EETGASGT---RKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERD 246
           +   +      R  +Q ++R+ +SR +  + P     ++       DS SS  EES+ R+
Sbjct: 581 DRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRN 640

Query: 247 TKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSED 292
             K K + +E K+     N+E ++R   ++      D  S+ +S +
Sbjct: 641 --KDKYRNQESKSSHRKENSESEKRMYSKSR-----DHNSSNNSRE 679



 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 38/207 (18%), Positives = 83/207 (40%), Gaps = 2/207 (0%)

Query: 69  QRYYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSSDQ 128
           +R+    K+E++   E+     +   +K  D+  N+ +       KE   ++ +++S ++
Sbjct: 378 ERWIKGDKSELNEIKENQRSPVRVKERKITDHR-NVSESPNRKNEKEKKVKDHKSNSKER 436

Query: 129 QDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEF 188
               N +K           ++   +SK   K K K+R  K  +  +K     +     E 
Sbjct: 437 DIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHEN 496

Query: 189 SEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTK 248
            +E       KGK   + + K + K L+  +   +  S +   D  A S S E +    K
Sbjct: 497 VKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHD-HSKSKEKDRRAQSRSRECDITKGK 555

Query: 249 KTKRKKREKKAHTSVANNEIQERTNKR 275
            +   +  +++ +   +  ++ RT+ R
Sbjct: 556 HSYNSRTRERSRSRDRSRRVRSRTHDR 582



 Score = 48.9 bits (115), Expect = 5e-06
 Identities = 52/280 (18%), Positives = 111/280 (39%), Gaps = 31/280 (11%)

Query: 26  EESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEISGTLED 85
           +E D    R  EK+M    +G   + +     +  S G D+E  R   + K   S + E 
Sbjct: 471 KERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEH 530

Query: 86  DFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSSDQQDITNGKKTSPQVKSST 145
           D  K+K  +++            G   Y           +S  ++ +  +  S +V+S T
Sbjct: 531 DHSKSKEKDRRAQSRSRECDITKGKHSY-----------NSRTRERSRSRDRSRRVRSRT 579

Query: 146 HESRKHKKSKKSHK------------KKQKKRSHKKQKKSKKEATDITADSSSEFSEETG 193
           H+ R   +SK+ H+            + +++R+   + +SK          SSE  E   
Sbjct: 580 HD-RDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREE--- 635

Query: 194 ASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRK 253
           +    K K  ++  K S +K   +    + ++S   +S +++     + ++    K K+ 
Sbjct: 636 SQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQS 695

Query: 254 KREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD 293
            ++ +  +S+  N+  E+        V  + + ++  E+D
Sbjct: 696 SQDNELKSSMLKNKEDEKIRS----SVEKENQKSKGQEND 731



 Score = 48.1 bits (113), Expect = 9e-06
 Identities = 33/137 (24%), Positives = 60/137 (43%), Gaps = 25/137 (18%)

Query: 156 KSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGT-------------RKGKQ 202
           KS  KK++K+ HK    S   ++D  + S S+ S ++  S +             RK  +
Sbjct: 180 KSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSR 239

Query: 203 PHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSS------------EESEERDTKKT 250
            HK++KK RKKS K  +   EAE+  +    +                 +   + D K+ 
Sbjct: 240 KHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKER 299

Query: 251 KRKKREKKAHTSVANNE 267
           K ++RE++   +  N++
Sbjct: 300 KNRERERERECNPPNSQ 316



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 53/272 (19%), Positives = 111/272 (40%), Gaps = 17/272 (6%)

Query: 27  ESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEISGTLEDD 86
           + D  ++ E+++      R  +RK+    +     +  +E+ ++     K+  S + E D
Sbjct: 382 KGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKV----KDHKSNSKERD 437

Query: 87  FLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSSDQQDITNGKKTSPQVKSSTH 146
             +    + K+ +           S  KE    + E DS   ++    K+   + K   H
Sbjct: 438 IRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSK-ERDSKHNRN--EEKRMRSRSKGRDH 494

Query: 147 ESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITAD-SSSEFSEETGASGTR-----KG 200
           E+ K K+ +   K K ++RS  K+K  + E+     D S S+  +    S +R     KG
Sbjct: 495 ENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKG 554

Query: 201 KQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAH 260
           K  +  + + R +S  +        S T   D S S       E++ ++ + + R ++  
Sbjct: 555 KHSYNSRTRERSRSRDRSR---RVRSRTHDRDRSRSKEYHRYREQEYRR-RGRSRSRERR 610

Query: 261 TSVANNEIQERTNKRTNWKVATDERSAESSED 292
           T    +  ++R  +R + + +  E S   ++D
Sbjct: 611 TPPGRSRSKDRRRRRRDSRSSEREESQSRNKD 642



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 29/89 (32%), Positives = 45/89 (50%), Gaps = 2/89 (2%)

Query: 203 PHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTS 262
           P  + KK  KK  K  +    + S++  S DS SSS     E  T++ K KKR+KK H  
Sbjct: 179 PKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEE-KSKKRKKK-HRK 236

Query: 263 VANNEIQERTNKRTNWKVATDERSAESSE 291
            +    +E+  ++ + K A+ E  AE+ E
Sbjct: 237 NSRKHKKEKKKRKKSKKSASSESEAENLE 265



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 35/124 (28%), Positives = 55/124 (44%), Gaps = 14/124 (11%)

Query: 123 TDSSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKK--RSHKKQKKSKKEATDI 180
           + SSD    ++ + +S    S +    K KK KK H+K  +K  +  KK+KKSKK A   
Sbjct: 199 SSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSA--- 255

Query: 181 TADSSSEFSEETGASGTRKGKQP---------HKRKKKSRKKSLKKPALFLEAESNTSHS 231
           +++S +E  E    S  R  + P          K   K+ +K  K      E E N  +S
Sbjct: 256 SSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERERECNPPNS 315

Query: 232 DDSA 235
             ++
Sbjct: 316 QPAS 319



 Score = 42.0 bits (97), Expect = 6e-04
 Identities = 46/263 (17%), Positives = 98/263 (37%), Gaps = 29/263 (11%)

Query: 21  HNKIQEES--------DMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYY 72
           HN+ +E+         D   ++E EKQ +   +  +R      S ++ S   + +  +  
Sbjct: 477 HNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSK 536

Query: 73  WRPKNEISGTLEDDFLKAK-SWNKKFYDYEANMP------------DRWGHSGYKELYPE 119
            + +   S + E D  K K S+N +  +   +              DR     Y     +
Sbjct: 537 EKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQ 596

Query: 120 EFET---DSSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKE 176
           E+       S ++    G+  S   +    +SR  ++ +   + K K R+ + +   +KE
Sbjct: 597 EYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKE 656

Query: 177 ATDITADSSSEFSEETGASGTRKGK-----QPHKRKKKSRKKSLKKPALFLEAESNTSHS 231
            ++      S+  +   ++ +R+ K      P  + K+S + +  K ++    E     S
Sbjct: 657 NSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRS 716

Query: 232 DDSASSSSEESEERDTKKTKRKK 254
                +   + +E D    K KK
Sbjct: 717 SVEKENQKSKGQENDHVHEKNKK 739



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 56/299 (18%), Positives = 114/299 (38%), Gaps = 28/299 (9%)

Query: 18  TDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKN 77
           +D+ +  +E+S   K +  +   +      KRK    S+S   S+  + E+Q        
Sbjct: 217 SDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASS-ESEAENLEAQPQSTVRPE 275

Query: 78  EISGTLEDDFLKAKSWNK----------KFYDYEANMPDRWGHSGYKELY---------- 117
           EI    E+ FL  KS  K          +  + E N P+    S  + L           
Sbjct: 276 EIPPIPENRFLMRKSPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKG 335

Query: 118 --PEEFETDS-SDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSK 174
             P  + T S S  +D     +T P  +     +++ + S      K  K    + K+++
Sbjct: 336 RGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQ 395

Query: 175 KEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDS 234
           +    +      + ++    S +   K   ++K K  K + K+  +   +E +  + +  
Sbjct: 396 RSPVRV---KERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKV 452

Query: 235 ASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD 293
              +  +S  +  +K+K K+R+ K H       ++ R+  R +  V   E+ ++S   D
Sbjct: 453 KKRAKSKSRSKSKEKSKSKERDSK-HNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKD 510



 Score = 36.2 bits (82), Expect = 0.035
 Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 2/69 (2%)

Query: 123 TDSSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITA 182
           + SS   D  +   +     SS  ES   +KSKK  +KK+ +++ +K KK KK+      
Sbjct: 196 SSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKK--RKKKHRKNSRKHKKEKKKRKKSKK 253

Query: 183 DSSSEFSEE 191
            +SSE   E
Sbjct: 254 SASSESEAE 262


>gi|50409756 SRp25 nuclear protein isoform 1 [Homo sapiens]
          Length = 360

 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 31/111 (27%), Positives = 63/111 (56%), Gaps = 4/111 (3%)

Query: 152 KKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQP---HKRKK 208
           +K  +S  + + + S K++KKS+K+ +   + S+S+  + + A G      P    + K+
Sbjct: 130 RKRSRSRSRSRGRGSEKRKKKSRKDTSRNCSASTSQGRKASTAPGAEASPSPCITERSKQ 189

Query: 209 KSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTK-KTKRKKREKK 258
           K+R+++    +    + S++S S  S+SSSS +  ++  K K KR+K++KK
Sbjct: 190 KARRRTRSSSSSSSSSSSSSSSSSSSSSSSSSDGRKKRGKYKDKRRKKKKK 240



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 32/153 (20%), Positives = 62/153 (40%), Gaps = 9/153 (5%)

Query: 123 TDSSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITA 182
           + SS     ++   +S    SS    ++ K   K  KKK+K++  KK+ K K EA  + A
Sbjct: 200 SSSSSSSSSSSSSSSSSSSSSSDGRKKRGKYKDKRRKKKKKRKKLKKKGKEKAEAQQVEA 259

Query: 183 DSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEES 242
                  +   ++G  +       ++KSR +++K           T    D+  S   + 
Sbjct: 260 LPGPSLDQWHRSAGEEEDGPVLTDEQKSRIQAMK---------PMTKEEWDARQSIIRKV 310

Query: 243 EERDTKKTKRKKREKKAHTSVANNEIQERTNKR 275
            + +T +T+  K + +    +   E     NK+
Sbjct: 311 VDPETGRTRLIKGDGEVLEEIVTKERHREINKQ 343



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 35/145 (24%), Positives = 63/145 (43%), Gaps = 15/145 (10%)

Query: 126 SDQQDITNGKKTSPQVKSSTHESRKHKKSKKSH---------KKKQKKRSHKKQKKSKKE 176
           S+++   + K TS    +ST + RK   +  +          + KQK R   +   S   
Sbjct: 144 SEKRKKKSRKDTSRNCSASTSQGRKASTAPGAEASPSPCITERSKQKARRRTRSSSSSSS 203

Query: 177 ATDITADSSSEFSEETGASGTRK-----GKQPHKRKKKSR-KKSLKKPALFLEAESNTSH 230
           ++  ++ SSS  S  + + G +K      K+  K+KK+ + KK  K+ A   + E+    
Sbjct: 204 SSSSSSSSSSSSSSSSSSDGRKKRGKYKDKRRKKKKKRKKLKKKGKEKAEAQQVEALPGP 263

Query: 231 SDDSASSSSEESEERDTKKTKRKKR 255
           S D    S+ E E+      ++K R
Sbjct: 264 SLDQWHRSAGEEEDGPVLTDEQKSR 288


>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
           [Homo sapiens]
          Length = 624

 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 38/171 (22%), Positives = 70/171 (40%), Gaps = 32/171 (18%)

Query: 122 ETDSSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDIT 181
           E +S    +   G+  S     S   S+ H + K+S + K + RSH + +  +K+     
Sbjct: 294 EPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRS-QSKHRSRSHNRSRSRQKDR---- 348

Query: 182 ADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEE 241
                           R+ K PHK++ KSR++   +         + SHS D    + E+
Sbjct: 349 ----------------RRSKSPHKKRSKSRERRKSR---------SRSHSRDKRKDTREK 383

Query: 242 SEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSED 292
            +E++  + K K REK+        + +ER   +   K    +R  +  +D
Sbjct: 384 IKEKE--RVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKD 432



 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 40/163 (24%), Positives = 72/163 (44%), Gaps = 7/163 (4%)

Query: 119 EEFETDSSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEAT 178
           +E E D   +++    K+   +   S     K KK KKS    +   + ++ + S +E  
Sbjct: 439 KEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERR 498

Query: 179 DITADSSSEFSEETGASGTRKGKQ---PHKRKKKSRKKSLKKPALF--LEAESNTSHSDD 233
              + SSS  S  T  +  RK  +   P  R KK +K+  ++  +    E E +TS    
Sbjct: 499 RRRSRSSSR-SPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKS 557

Query: 234 SASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRT 276
           S     +E  E+++   K K+  K+  +SV + E+ ++   RT
Sbjct: 558 SNDRDGKEKLEKNSTSLKEKEHNKEPDSSV-SKEVDDKDAPRT 599



 Score = 48.9 bits (115), Expect = 5e-06
 Identities = 35/151 (23%), Positives = 69/151 (45%), Gaps = 15/151 (9%)

Query: 144 STHESRKHKKSKKSHKKKQKKRS---HKKQKKSKKEATDITADSSSEFSEETGASGTRKG 200
           S H SR H +S+   ++K ++RS   HKK+ KS++     +   S +  ++T      K 
Sbjct: 331 SKHRSRSHNRSRS--RQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDT----REKI 384

Query: 201 KQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAH 260
           K+  + K+K R+K  ++       +      +   +   ++  E+D +K K K RE++  
Sbjct: 385 KEKERVKEKDREKERER------EKEREKEKERGKNKDRDKEREKDREKDKEKDRERERE 438

Query: 261 TSVANNEIQERTNKRTNWKVATDERSAESSE 291
                +  +E+  ++   K    +RS E  E
Sbjct: 439 KEHEKDRDKEKEKEQDKEKEREKDRSKEIDE 469



 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 41/173 (23%), Positives = 74/173 (42%), Gaps = 15/173 (8%)

Query: 126 SDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSS 185
           S Q+D    K  SP  K S  +SR+ +KS+     + K++  +++ K K+   +   +  
Sbjct: 343 SRQKDRRRSK--SPHKKRS--KSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKE 398

Query: 186 SEFSEETGASGTR-KGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESE- 243
            E  +E      R K K   K ++K R+K  +K     E E    H  D      +E + 
Sbjct: 399 REREKEREKEKERGKNKDRDKEREKDREKDKEKDR---EREREKEHEKDRDKEKEKEQDK 455

Query: 244 ----ERDTKK--TKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESS 290
               E+D  K   +++K++KK+ T   +     R+   +  +     RS+  S
Sbjct: 456 EKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRS 508



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 48/263 (18%), Positives = 102/263 (38%), Gaps = 22/263 (8%)

Query: 20  AHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEI 79
           +H++ + +    KI+E E+  E      + +       + R    D + +R   R K++ 
Sbjct: 371 SHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKE 430

Query: 80  SGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSSDQQDITNGKK--T 137
               +D   + +  ++K  D E            K+   E  E    D++  T  +    
Sbjct: 431 ----KDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNA 486

Query: 138 SPQVKSSTHESRKHK--------KSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFS 189
           S + +SS+ E R+ +        ++ K+ K+K  +    + +  K +  +   D  SE  
Sbjct: 487 SRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERR 546

Query: 190 EETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKK 249
           E   ++  RK       K+K  K S         +     H+ +  SS S+E +++D  +
Sbjct: 547 ERERSTSMRKSSNDRDGKEKLEKNS--------TSLKEKEHNKEPDSSVSKEVDDKDAPR 598

Query: 250 TKRKKREKKAHTSVANNEIQERT 272
           T+  K +   +  +    +  +T
Sbjct: 599 TEENKIQHNGNCQLNEENLSTKT 621



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 47/231 (20%), Positives = 95/231 (41%), Gaps = 21/231 (9%)

Query: 47  TKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPD 106
           T+ K   SS S  R     + SQ  +    +  S + + D  ++KS +KK          
Sbjct: 312 TRSKSRSSSKSHSRR----KRSQSKHRSRSHNRSRSRQKDRRRSKSPHKK---------- 357

Query: 107 RWGHSGYKELYPEEFETDSSDQQDITNGK-KTSPQVKSSTHESRKHKKSKKSHKKKQKKR 165
               S  +E       + S D++  T  K K   +VK    E  + ++ ++  +K++ K 
Sbjct: 358 ---RSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKN 414

Query: 166 SHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAE 225
             + +++ K    D   D   E  E+       K K+  + K+K R+K   K       +
Sbjct: 415 KDRDKEREKDREKDKEKDRERE-REKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKK 473

Query: 226 SNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRT 276
              S +   + ++S  S  R + + +R++R + +  S   ++  +R + R+
Sbjct: 474 DKKSRTPPRSYNASRRS--RSSSRERRRRRSRSSSRSPRTSKTIKRKSSRS 522



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 27/180 (15%), Positives = 73/180 (40%), Gaps = 1/180 (0%)

Query: 114 KELYPEEFETDSSDQQDITNGKKTSPQVKSSTHESRK-HKKSKKSHKKKQKKRSHKKQKK 172
           KE   E+    + D+       +   + K    E  K H+K +   K+K++ +  +++K 
Sbjct: 403 KEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKD 462

Query: 173 SKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSD 232
             KE  +         +     + +R+ +   + +++ R +S  +     +     S   
Sbjct: 463 RSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRS 522

Query: 233 DSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSED 292
            S  S +++ ++R+ ++    +R ++  ++       +R  K    K +T  +  E +++
Sbjct: 523 PSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKE 582



 Score = 35.8 bits (81), Expect = 0.046
 Identities = 26/132 (19%), Positives = 54/132 (40%), Gaps = 7/132 (5%)

Query: 168 KKQKKSKKEATDITADSSSEFSEETGASGTRKG--KQPHKRKK-----KSRKKSLKKPAL 220
           K+ ++  K   +  +  S+    E+G S  RKG   + H R K     KS  +  +  + 
Sbjct: 273 KELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSK 332

Query: 221 FLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKV 280
                 N S S       S+   ++ +K  +R+K   ++H+     + +E+  ++   K 
Sbjct: 333 HRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKE 392

Query: 281 ATDERSAESSED 292
              E+  E  ++
Sbjct: 393 KDREKEREREKE 404


>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
           [Homo sapiens]
          Length = 508

 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 38/171 (22%), Positives = 70/171 (40%), Gaps = 32/171 (18%)

Query: 122 ETDSSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDIT 181
           E +S    +   G+  S     S   S+ H + K+S + K + RSH + +  +K+     
Sbjct: 178 EPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRS-QSKHRSRSHNRSRSRQKDR---- 232

Query: 182 ADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEE 241
                           R+ K PHK++ KSR++   +         + SHS D    + E+
Sbjct: 233 ----------------RRSKSPHKKRSKSRERRKSR---------SRSHSRDKRKDTREK 267

Query: 242 SEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSED 292
            +E++  + K K REK+        + +ER   +   K    +R  +  +D
Sbjct: 268 IKEKE--RVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKD 316



 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 40/163 (24%), Positives = 72/163 (44%), Gaps = 7/163 (4%)

Query: 119 EEFETDSSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEAT 178
           +E E D   +++    K+   +   S     K KK KKS    +   + ++ + S +E  
Sbjct: 323 KEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERR 382

Query: 179 DITADSSSEFSEETGASGTRKGKQ---PHKRKKKSRKKSLKKPALF--LEAESNTSHSDD 233
              + SSS  S  T  +  RK  +   P  R KK +K+  ++  +    E E +TS    
Sbjct: 383 RRRSRSSSR-SPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKS 441

Query: 234 SASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRT 276
           S     +E  E+++   K K+  K+  +SV + E+ ++   RT
Sbjct: 442 SNDRDGKEKLEKNSTSLKEKEHNKEPDSSV-SKEVDDKDAPRT 483



 Score = 48.9 bits (115), Expect = 5e-06
 Identities = 35/151 (23%), Positives = 69/151 (45%), Gaps = 15/151 (9%)

Query: 144 STHESRKHKKSKKSHKKKQKKRS---HKKQKKSKKEATDITADSSSEFSEETGASGTRKG 200
           S H SR H +S+   ++K ++RS   HKK+ KS++     +   S +  ++T      K 
Sbjct: 215 SKHRSRSHNRSRS--RQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDT----REKI 268

Query: 201 KQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAH 260
           K+  + K+K R+K  ++       +      +   +   ++  E+D +K K K RE++  
Sbjct: 269 KEKERVKEKDREKERER------EKEREKEKERGKNKDRDKEREKDREKDKEKDRERERE 322

Query: 261 TSVANNEIQERTNKRTNWKVATDERSAESSE 291
                +  +E+  ++   K    +RS E  E
Sbjct: 323 KEHEKDRDKEKEKEQDKEKEREKDRSKEIDE 353



 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 41/173 (23%), Positives = 74/173 (42%), Gaps = 15/173 (8%)

Query: 126 SDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSS 185
           S Q+D    K  SP  K S  +SR+ +KS+     + K++  +++ K K+   +   +  
Sbjct: 227 SRQKDRRRSK--SPHKKRS--KSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKE 282

Query: 186 SEFSEETGASGTR-KGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESE- 243
            E  +E      R K K   K ++K R+K  +K     E E    H  D      +E + 
Sbjct: 283 REREKEREKEKERGKNKDRDKEREKDREKDKEKDR---EREREKEHEKDRDKEKEKEQDK 339

Query: 244 ----ERDTKK--TKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESS 290
               E+D  K   +++K++KK+ T   +     R+   +  +     RS+  S
Sbjct: 340 EKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRS 392



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 48/263 (18%), Positives = 102/263 (38%), Gaps = 22/263 (8%)

Query: 20  AHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEI 79
           +H++ + +    KI+E E+  E      + +       + R    D + +R   R K++ 
Sbjct: 255 SHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKE 314

Query: 80  SGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSSDQQDITNGKK--T 137
               +D   + +  ++K  D E            K+   E  E    D++  T  +    
Sbjct: 315 ----KDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNA 370

Query: 138 SPQVKSSTHESRKHK--------KSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFS 189
           S + +SS+ E R+ +        ++ K+ K+K  +    + +  K +  +   D  SE  
Sbjct: 371 SRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERR 430

Query: 190 EETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKK 249
           E   ++  RK       K+K  K S         +     H+ +  SS S+E +++D  +
Sbjct: 431 ERERSTSMRKSSNDRDGKEKLEKNS--------TSLKEKEHNKEPDSSVSKEVDDKDAPR 482

Query: 250 TKRKKREKKAHTSVANNEIQERT 272
           T+  K +   +  +    +  +T
Sbjct: 483 TEENKIQHNGNCQLNEENLSTKT 505



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 47/231 (20%), Positives = 95/231 (41%), Gaps = 21/231 (9%)

Query: 47  TKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPD 106
           T+ K   SS S  R     + SQ  +    +  S + + D  ++KS +KK          
Sbjct: 196 TRSKSRSSSKSHSRR----KRSQSKHRSRSHNRSRSRQKDRRRSKSPHKK---------- 241

Query: 107 RWGHSGYKELYPEEFETDSSDQQDITNGK-KTSPQVKSSTHESRKHKKSKKSHKKKQKKR 165
               S  +E       + S D++  T  K K   +VK    E  + ++ ++  +K++ K 
Sbjct: 242 ---RSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKN 298

Query: 166 SHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAE 225
             + +++ K    D   D   E  E+       K K+  + K+K R+K   K       +
Sbjct: 299 KDRDKEREKDREKDKEKDRERE-REKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKK 357

Query: 226 SNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRT 276
              S +   + ++S  S  R + + +R++R + +  S   ++  +R + R+
Sbjct: 358 DKKSRTPPRSYNASRRS--RSSSRERRRRRSRSSSRSPRTSKTIKRKSSRS 406



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 27/180 (15%), Positives = 73/180 (40%), Gaps = 1/180 (0%)

Query: 114 KELYPEEFETDSSDQQDITNGKKTSPQVKSSTHESRK-HKKSKKSHKKKQKKRSHKKQKK 172
           KE   E+    + D+       +   + K    E  K H+K +   K+K++ +  +++K 
Sbjct: 287 KEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKD 346

Query: 173 SKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSD 232
             KE  +         +     + +R+ +   + +++ R +S  +     +     S   
Sbjct: 347 RSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRS 406

Query: 233 DSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSED 292
            S  S +++ ++R+ ++    +R ++  ++       +R  K    K +T  +  E +++
Sbjct: 407 PSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKE 466



 Score = 35.8 bits (81), Expect = 0.046
 Identities = 26/132 (19%), Positives = 54/132 (40%), Gaps = 7/132 (5%)

Query: 168 KKQKKSKKEATDITADSSSEFSEETGASGTRKG--KQPHKRKK-----KSRKKSLKKPAL 220
           K+ ++  K   +  +  S+    E+G S  RKG   + H R K     KS  +  +  + 
Sbjct: 157 KELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSK 216

Query: 221 FLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKV 280
                 N S S       S+   ++ +K  +R+K   ++H+     + +E+  ++   K 
Sbjct: 217 HRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKE 276

Query: 281 ATDERSAESSED 292
              E+  E  ++
Sbjct: 277 KDREKEREREKE 288


>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
           sapiens]
          Length = 570

 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 43/252 (17%), Positives = 109/252 (43%), Gaps = 22/252 (8%)

Query: 25  QEESDMW----KIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEIS 80
           ++E  MW    KIRELE++M +  +  +++       ++R     +E +   WR + +I 
Sbjct: 334 RQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKI- 392

Query: 81  GTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSSDQQDITNGKKTSPQ 140
                     +   +K  + E  M ++    G +E    E E +  +Q++     K   Q
Sbjct: 393 ----------REQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEE-----KMRRQ 437

Query: 141 VKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKG 200
            +    + +K ++ ++  +++++    +++K  ++E      ++  +  EE       K 
Sbjct: 438 EEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKI 497

Query: 201 KQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTK--KTKRKKREKK 258
           ++  K+ ++  +K  ++  +  E E      ++      E+ +E++ K  + + K RE++
Sbjct: 498 REQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQE 557

Query: 259 AHTSVANNEIQE 270
                   ++QE
Sbjct: 558 VRLRQQEEKMQE 569


>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
          Length = 2426

 Score = 51.6 bits (122), Expect = 8e-07
 Identities = 46/202 (22%), Positives = 86/202 (42%), Gaps = 21/202 (10%)

Query: 106  DRWGHSGYKELYPEEFETDSSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQK-- 163
            DR   S      PE     SS+++D     +   +VK +  +S+K+K   K  K+K++  
Sbjct: 1764 DRSAASPVVSSMPERASESSSEEKD---DYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDS 1820

Query: 164  ------KRSHKKQKKSKKEATDITADSSSEFSE-ETGASGTRKGKQPHKRKKKSRKKSLK 216
                  KRS   + KS+K  ++  + +    S+ ++  S TR   +  +R++ SR +S  
Sbjct: 1821 SLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKS 1880

Query: 217  KPALFLEAES---NTSHSDDSASSSSEESEERDTKKTKRKK-----REKKAHTSVANNEI 268
            +    +  E    +  H   S     + S  RD +KT R +     R  ++HT  +    
Sbjct: 1881 RGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTP-SRRRR 1939

Query: 269  QERTNKRTNWKVATDERSAESS 290
                 +R ++ ++   RS   S
Sbjct: 1940 SRSVGRRRSFSISPSRRSRTPS 1961



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 23/69 (33%), Positives = 38/69 (55%), Gaps = 10/69 (14%)

Query: 136 KTSPQVKSSTHESRKHKK--SKKSHKKKQKKRSHKKQKKSKKEAT--------DITADSS 185
           +T P  +  T +S+KHKK  +KK  KKK+K++ +K+Q +  +  T        D+ +DS 
Sbjct: 96  QTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESESKTKSHDDGNIDLESDSF 155

Query: 186 SEFSEETGA 194
            +F  E  A
Sbjct: 156 LKFDSEPSA 164



 Score = 33.9 bits (76), Expect = 0.17
 Identities = 23/150 (15%), Positives = 63/150 (42%), Gaps = 1/150 (0%)

Query: 125  SSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADS 184
            S   +  T  +  S + + S+  SR   + ++S  K+++KRS K + KS++     ++  
Sbjct: 1854 SKSHRSQTRSRSRSRRRRRSSR-SRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSR 1912

Query: 185  SSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEE 244
             +  +    +    +  + H   ++ R +S+ +   F  + S  S +    S +      
Sbjct: 1913 DNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSR 1972

Query: 245  RDTKKTKRKKREKKAHTSVANNEIQERTNK 274
              +++++   R  +  +  +    + R ++
Sbjct: 1973 TPSRRSRTPSRRSRTPSRRSRTPSRRRRSR 2002



 Score = 28.1 bits (61), Expect = 9.6
 Identities = 19/69 (27%), Positives = 28/69 (40%), Gaps = 11/69 (15%)

Query: 169 KQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFL----EA 224
           K+   K     +  D + E         T+K K+  K K K +KK  +K   +     E+
Sbjct: 84  KEGSRKSRCVSVQTDPTDEIP-------TKKSKKHKKHKNKKKKKKKEKEKKYKRQPEES 136

Query: 225 ESNTSHSDD 233
           ES T   DD
Sbjct: 137 ESKTKSHDD 145


>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
          Length = 2303

 Score = 51.6 bits (122), Expect = 8e-07
 Identities = 46/202 (22%), Positives = 86/202 (42%), Gaps = 21/202 (10%)

Query: 106  DRWGHSGYKELYPEEFETDSSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQK-- 163
            DR   S      PE     SS+++D     +   +VK +  +S+K+K   K  K+K++  
Sbjct: 1764 DRSAASPVVSSMPERASESSSEEKD---DYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDS 1820

Query: 164  ------KRSHKKQKKSKKEATDITADSSSEFSE-ETGASGTRKGKQPHKRKKKSRKKSLK 216
                  KRS   + KS+K  ++  + +    S+ ++  S TR   +  +R++ SR +S  
Sbjct: 1821 SLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKS 1880

Query: 217  KPALFLEAES---NTSHSDDSASSSSEESEERDTKKTKRKK-----REKKAHTSVANNEI 268
            +    +  E    +  H   S     + S  RD +KT R +     R  ++HT  +    
Sbjct: 1881 RGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTP-SRRRR 1939

Query: 269  QERTNKRTNWKVATDERSAESS 290
                 +R ++ ++   RS   S
Sbjct: 1940 SRSVGRRRSFSISPSRRSRTPS 1961



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 23/69 (33%), Positives = 38/69 (55%), Gaps = 10/69 (14%)

Query: 136 KTSPQVKSSTHESRKHKK--SKKSHKKKQKKRSHKKQKKSKKEAT--------DITADSS 185
           +T P  +  T +S+KHKK  +KK  KKK+K++ +K+Q +  +  T        D+ +DS 
Sbjct: 96  QTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESESKTKSHDDGNIDLESDSF 155

Query: 186 SEFSEETGA 194
            +F  E  A
Sbjct: 156 LKFDSEPSA 164



 Score = 33.9 bits (76), Expect = 0.17
 Identities = 23/150 (15%), Positives = 63/150 (42%), Gaps = 1/150 (0%)

Query: 125  SSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADS 184
            S   +  T  +  S + + S+  SR   + ++S  K+++KRS K + KS++     ++  
Sbjct: 1854 SKSHRSQTRSRSRSRRRRRSSR-SRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSR 1912

Query: 185  SSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEE 244
             +  +    +    +  + H   ++ R +S+ +   F  + S  S +    S +      
Sbjct: 1913 DNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSR 1972

Query: 245  RDTKKTKRKKREKKAHTSVANNEIQERTNK 274
              +++++   R  +  +  +    + R ++
Sbjct: 1973 TPSRRSRTPSRRSRTPSRRSRTPSRRRRSR 2002



 Score = 28.1 bits (61), Expect = 9.6
 Identities = 19/69 (27%), Positives = 28/69 (40%), Gaps = 11/69 (15%)

Query: 169 KQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFL----EA 224
           K+   K     +  D + E         T+K K+  K K K +KK  +K   +     E+
Sbjct: 84  KEGSRKSRCVSVQTDPTDEIP-------TKKSKKHKKHKNKKKKKKKEKEKKYKRQPEES 136

Query: 225 ESNTSHSDD 233
           ES T   DD
Sbjct: 137 ESKTKSHDD 145


>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
          Length = 2454

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 70/309 (22%), Positives = 123/309 (39%), Gaps = 47/309 (15%)

Query: 18   TDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKN 77
            TD  +K+  +   +   E+ K  E      K K L + + +   DG  + ++++    K+
Sbjct: 880  TDGVDKLSGKEQSFTSLEVRKVAETK---EKSKHLKTKTCKKVQDGLSDIAEKFL--KKD 934

Query: 78   EISGTLEDDFLKAKSWN---KKFYDYEAN---MPDRW-GHSGYKELYPEEFETD------ 124
            +   T EDD  ++K      KK  D++     M  ++   S   E  PE  E        
Sbjct: 935  QSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGI 994

Query: 125  SSDQQDITNGKKTSPQVKSSTH--------------------ESRKHKKSKKSHKKKQKK 164
               +   T+G+K S +++  T                     +S + KKSK     ++KK
Sbjct: 995  KQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKK 1054

Query: 165  RSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEA 224
            R     K S+K     ++D+     +E G + + K     KR +   +++L       E 
Sbjct: 1055 RCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRL---KRIELRERRNLSSKRNTKEI 1111

Query: 225  ESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDE 284
            +S +S SD      +EES E + KK +R   +KKA           RT+ +      T  
Sbjct: 1112 QSGSSSSD------AEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSS 1165

Query: 285  RSAESSEDD 293
             S++  +DD
Sbjct: 1166 SSSDIEDDD 1174



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 64/285 (22%), Positives = 112/285 (39%), Gaps = 40/285 (14%)

Query: 18   TDAHNKIQEESDMWKIRELEKQMEDAY-RGTKRKMLPSSSSRMRSDGFDEESQRYYWRPK 76
            +D   K   + D     E +K    AY R  KR  L   SSR R D    ++++Y  +  
Sbjct: 1023 SDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMK-- 1080

Query: 77   NEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSSDQQDITNGKK 136
                   ED    +    K+                  EL      +   + ++I +G  
Sbjct: 1081 -------EDGCNSSDKRLKRI-----------------ELRERRNLSSKRNTKEIQSGSS 1116

Query: 137  TSPQVKSSTHESRKHKKSKKSHKKK-----QKKRSHKKQKKSKKEATDITADSSSEFSEE 191
            +S   +SS  E  K KK + S KKK     +KKR+  +    +K+A DIT+ SSS+  ++
Sbjct: 1117 SSDAEESS--EDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQA-DITSSSSSDIEDD 1173

Query: 192  TGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTK 251
               S         K K  +    L     F ++  + + S     +  ++ ++ D +   
Sbjct: 1174 DQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRI 1233

Query: 252  RKK---REKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD 293
             KK    E KA+ S  ++E     ++    K  T +++ E+  D+
Sbjct: 1234 AKKMLLEEIKANLS--SDEDGSSDDEPEEGKKRTGKQNEENPGDE 1276



 Score = 42.0 bits (97), Expect = 6e-04
 Identities = 50/266 (18%), Positives = 102/266 (38%), Gaps = 17/266 (6%)

Query: 32   KIRELEKQMEDAYRGTKRKM-------LPSSSSRMRSDGFDEESQRYYWRPKNEISGTLE 84
            K+ ++E+Q E +  GT++          P    ++++   D E +    R K        
Sbjct: 963  KVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDEL 1022

Query: 85   DDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSSDQQDITNGKKTSPQVKSS 144
             D+ +  +      D   +   + G  G ++   +     S  +QD ++    S   K S
Sbjct: 1023 SDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSS----SDTEKYS 1078

Query: 145  THESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETG------ASGTR 198
              E   +   K+  + + ++R +   K++ KE    ++ S +E S E         S  +
Sbjct: 1079 MKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKK 1138

Query: 199  KGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKK 258
            K     ++K+ S + S K+    + + S++   DD  +S  E S +    K   +     
Sbjct: 1139 KAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLS 1198

Query: 259  AHTSVANNEIQERTNKRTNWKVATDE 284
            +HT    +   E  +K     V  D+
Sbjct: 1199 SHTGFCQSSGDEALSKSVPVTVDDDD 1224



 Score = 42.0 bits (97), Expect = 6e-04
 Identities = 44/171 (25%), Positives = 65/171 (38%), Gaps = 29/171 (16%)

Query: 144  STHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEF---SEETGASGTRKG 200
            S  ES + KK+K    K+ K R+ +K      E +D      SE    SE+     TR  
Sbjct: 1310 SDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSA 1369

Query: 201  KQP--------HKRKKKSRK-------KSLKKPALFLEAESNTSHSDDSASSSSEESEER 245
            K+         +K+KKK R+        S  K     E E      ++      EE +E 
Sbjct: 1370 KKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDEN 1429

Query: 246  DTKKTKRKKREK--------KAHTSVANNEIQERTNKRTNWKVATDERSAE 288
            D  K+  K R+K        K  T   N   +E   ++   ++A  ER  E
Sbjct: 1430 DDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRK---RIAERERERE 1477



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 48/184 (26%), Positives = 77/184 (41%), Gaps = 37/184 (20%)

Query: 125  SSDQQDITNGKK---TSPQVK--SSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATD 179
            S+D  D  +GK+   TS +V+  + T E  KH K+K   KK Q   S   +K  KK+ +D
Sbjct: 879  STDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTC-KKVQDGLSDIAEKFLKKDQSD 937

Query: 180  ITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSS 239
             T++   + S++    GT + K+P   KKK            ++ E     S D      
Sbjct: 938  ETSEDDKKQSKK----GTEEKKKPSDFKKK-----------VIKMEQQYESSSDGTEKLP 982

Query: 240  EESE-----------ERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAE 288
            E  E           +  T   ++K ++ +  TS   +E+ +   K T         S +
Sbjct: 983  EREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTG-----KGDSCD 1037

Query: 289  SSED 292
            SSED
Sbjct: 1038 SSED 1041



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 49/228 (21%), Positives = 83/228 (36%), Gaps = 27/228 (11%)

Query: 19   DAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNE 78
            +A N++  ESD     E  K+    +R  + K+  S       DG   E ++   +   E
Sbjct: 1277 EAKNQVNSESD--SDSEESKKPRYRHRLLRHKLTVS-------DGESGEEKKTKPKEHKE 1327

Query: 79   ISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSSDQQDITNGKKTS 138
            + G            N++    E +    +  SG  E   E  E++   +    + KK  
Sbjct: 1328 VKGR-----------NRRKVSSEDSEDSDFQESGVSE---EVSESEDEQRPRTRSAKKAE 1373

Query: 139  PQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTR 198
             +       S K KK ++  K ++   S  K    ++E      +   E  EE       
Sbjct: 1374 LE---ENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDEND 1430

Query: 199  KGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERD 246
              K P K +KK R K LK   L  E ++     ++     +E   ER+
Sbjct: 1431 DSKSPGKGRKKIR-KILKDDKLRTETQNALKEEEERRKRIAERERERE 1477



 Score = 38.9 bits (89), Expect = 0.005
 Identities = 35/179 (19%), Positives = 67/179 (37%), Gaps = 31/179 (17%)

Query: 119  EEFETDSSDQQDITNGKKTSPQVKSSTHESRKHKKS----KKSHKKKQKKRSHKKQKKSK 174
            EE +   + + D  + +   P+ +   H   +HK +    +   +KK K + HK+ K   
Sbjct: 1276 EEAKNQVNSESDSDSEESKKPRYR---HRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRN 1332

Query: 175  KEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDS 234
            +          S+F E    SG  +     + +++ R +S KK  L              
Sbjct: 1333 RRKVSSEDSEDSDFQE----SGVSEEVSESEDEQRPRTRSAKKAEL-------------- 1374

Query: 235  ASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD 293
                  E  +R  K+ K+++R K    S + N+      +    +   +E   E  E+D
Sbjct: 1375 ------EENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEED 1427



 Score = 35.8 bits (81), Expect = 0.046
 Identities = 29/172 (16%), Positives = 61/172 (35%), Gaps = 1/172 (0%)

Query: 122  ETDSSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDIT 181
            + D S   +   GKK + +         + K    S      + S K + + +     +T
Sbjct: 1249 DEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLT 1308

Query: 182  ADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEE 241
                    E+       K  +   R+K S + S              S S+D     +  
Sbjct: 1309 VSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRS 1368

Query: 242  SEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD 293
            +++ + ++ +R  ++KK    +   E     NK +N +   +E+  E  E++
Sbjct: 1369 AKKAELEENQRSYKQKKKRRRIKVQEDSSSENK-SNSEEEEEEKEEEEEEEE 1419



 Score = 35.4 bits (80), Expect = 0.060
 Identities = 58/298 (19%), Positives = 108/298 (36%), Gaps = 37/298 (12%)

Query: 26   EESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEIS-GTLE 84
            E++   K R   K+     +  KR  L +S+ R ++D     S       +N I  G+ +
Sbjct: 1125 EDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSD 1184

Query: 85   DDFLKAKSWNKKFYDYEANMPDRWGHSGYKEL-YPEEFETDSSDQQDITNGKKTSPQVK- 142
            +  +K  + N     +          +  K +    + + D +D ++    K    ++K 
Sbjct: 1185 EQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKA 1244

Query: 143  --SSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEET-------- 192
              SS  +     + ++  K+  K+       +  K   +  +DS SE S++         
Sbjct: 1245 NLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLR 1304

Query: 193  -------GASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEER 245
                   G SG  K  +P + K+   +   K       +  ++  SD   S  SEE  E 
Sbjct: 1305 HKLTVSDGESGEEKKTKPKEHKEVKGRNRRKV------SSEDSEDSDFQESGVSEEVSES 1358

Query: 246  DTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATD----------ERSAESSEDD 293
            + ++  R +  KKA     N    ++  KR   KV  D          E   E  E++
Sbjct: 1359 EDEQRPRTRSAKKAELE-ENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEE 1415



 Score = 34.7 bits (78), Expect = 0.10
 Identities = 40/200 (20%), Positives = 79/200 (39%), Gaps = 31/200 (15%)

Query: 110 HSGYKELYPEEFETDSSDQQDITNGKKTSPQVKSSTHESRKHKKSKKS--HKKKQKKRSH 167
           H+ +K LY  + +    D+      +K       S  +++K K +K S   KKK++ +S 
Sbjct: 720 HTNHKTLYDLKTQAGKDDK----GKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSE 775

Query: 168 KKQKKSKKE-------------ATDITADSSSEFSEETGASGTRKG--KQPHKRKKKSRK 212
                S+ E              T     ++ +F        ++KG   Q HK  K S++
Sbjct: 776 SSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQE 835

Query: 213 KSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTK-RKKREKKAHTSVANNEIQER 271
            S         ++      +    SS+E + ++DT   + R +  KK   S + + + + 
Sbjct: 836 GS---------SDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKL 886

Query: 272 TNKRTNWKVATDERSAESSE 291
           + K  ++      + AE+ E
Sbjct: 887 SGKEQSFTSLEVRKVAETKE 906



 Score = 28.5 bits (62), Expect = 7.3
 Identities = 16/64 (25%), Positives = 33/64 (51%), Gaps = 7/64 (10%)

Query: 230 HSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAES 289
           +S +  +SSSE+S+   + ++KRK        S+    ++    K  + +   ++ S E+
Sbjct: 59  NSKEEGTSSSEKSKSSGSSRSKRK-------PSIVTKYVESDDEKPLDDETVNEDASNEN 111

Query: 290 SEDD 293
           SE+D
Sbjct: 112 SEND 115


>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
          Length = 2492

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 70/309 (22%), Positives = 123/309 (39%), Gaps = 47/309 (15%)

Query: 18   TDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKN 77
            TD  +K+  +   +   E+ K  E      K K L + + +   DG  + ++++    K+
Sbjct: 918  TDGVDKLSGKEQSFTSLEVRKVAETK---EKSKHLKTKTCKKVQDGLSDIAEKFL--KKD 972

Query: 78   EISGTLEDDFLKAKSWN---KKFYDYEAN---MPDRW-GHSGYKELYPEEFETD------ 124
            +   T EDD  ++K      KK  D++     M  ++   S   E  PE  E        
Sbjct: 973  QSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGI 1032

Query: 125  SSDQQDITNGKKTSPQVKSSTH--------------------ESRKHKKSKKSHKKKQKK 164
               +   T+G+K S +++  T                     +S + KKSK     ++KK
Sbjct: 1033 KQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKK 1092

Query: 165  RSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEA 224
            R     K S+K     ++D+     +E G + + K     KR +   +++L       E 
Sbjct: 1093 RCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRL---KRIELRERRNLSSKRNTKEI 1149

Query: 225  ESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDE 284
            +S +S SD      +EES E + KK +R   +KKA           RT+ +      T  
Sbjct: 1150 QSGSSSSD------AEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSS 1203

Query: 285  RSAESSEDD 293
             S++  +DD
Sbjct: 1204 SSSDIEDDD 1212



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 64/285 (22%), Positives = 112/285 (39%), Gaps = 40/285 (14%)

Query: 18   TDAHNKIQEESDMWKIRELEKQMEDAY-RGTKRKMLPSSSSRMRSDGFDEESQRYYWRPK 76
            +D   K   + D     E +K    AY R  KR  L   SSR R D    ++++Y  +  
Sbjct: 1061 SDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMK-- 1118

Query: 77   NEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSSDQQDITNGKK 136
                   ED    +    K+                  EL      +   + ++I +G  
Sbjct: 1119 -------EDGCNSSDKRLKRI-----------------ELRERRNLSSKRNTKEIQSGSS 1154

Query: 137  TSPQVKSSTHESRKHKKSKKSHKKK-----QKKRSHKKQKKSKKEATDITADSSSEFSEE 191
            +S   +SS  E  K KK + S KKK     +KKR+  +    +K+A DIT+ SSS+  ++
Sbjct: 1155 SSDAEESS--EDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQA-DITSSSSSDIEDD 1211

Query: 192  TGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTK 251
               S         K K  +    L     F ++  + + S     +  ++ ++ D +   
Sbjct: 1212 DQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRI 1271

Query: 252  RKK---REKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD 293
             KK    E KA+ S  ++E     ++    K  T +++ E+  D+
Sbjct: 1272 AKKMLLEEIKANLS--SDEDGSSDDEPEEGKKRTGKQNEENPGDE 1314



 Score = 42.0 bits (97), Expect = 6e-04
 Identities = 50/266 (18%), Positives = 102/266 (38%), Gaps = 17/266 (6%)

Query: 32   KIRELEKQMEDAYRGTKRKM-------LPSSSSRMRSDGFDEESQRYYWRPKNEISGTLE 84
            K+ ++E+Q E +  GT++          P    ++++   D E +    R K        
Sbjct: 1001 KVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDEL 1060

Query: 85   DDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSSDQQDITNGKKTSPQVKSS 144
             D+ +  +      D   +   + G  G ++   +     S  +QD ++    S   K S
Sbjct: 1061 SDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSS----SDTEKYS 1116

Query: 145  THESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETG------ASGTR 198
              E   +   K+  + + ++R +   K++ KE    ++ S +E S E         S  +
Sbjct: 1117 MKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKK 1176

Query: 199  KGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKK 258
            K     ++K+ S + S K+    + + S++   DD  +S  E S +    K   +     
Sbjct: 1177 KAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLS 1236

Query: 259  AHTSVANNEIQERTNKRTNWKVATDE 284
            +HT    +   E  +K     V  D+
Sbjct: 1237 SHTGFCQSSGDEALSKSVPVTVDDDD 1262



 Score = 42.0 bits (97), Expect = 6e-04
 Identities = 44/171 (25%), Positives = 65/171 (38%), Gaps = 29/171 (16%)

Query: 144  STHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEF---SEETGASGTRKG 200
            S  ES + KK+K    K+ K R+ +K      E +D      SE    SE+     TR  
Sbjct: 1348 SDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSA 1407

Query: 201  KQP--------HKRKKKSRK-------KSLKKPALFLEAESNTSHSDDSASSSSEESEER 245
            K+         +K+KKK R+        S  K     E E      ++      EE +E 
Sbjct: 1408 KKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDEN 1467

Query: 246  DTKKTKRKKREK--------KAHTSVANNEIQERTNKRTNWKVATDERSAE 288
            D  K+  K R+K        K  T   N   +E   ++   ++A  ER  E
Sbjct: 1468 DDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRK---RIAERERERE 1515



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 48/184 (26%), Positives = 77/184 (41%), Gaps = 37/184 (20%)

Query: 125  SSDQQDITNGKK---TSPQVK--SSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATD 179
            S+D  D  +GK+   TS +V+  + T E  KH K+K   KK Q   S   +K  KK+ +D
Sbjct: 917  STDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTC-KKVQDGLSDIAEKFLKKDQSD 975

Query: 180  ITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSS 239
             T++   + S++    GT + K+P   KKK            ++ E     S D      
Sbjct: 976  ETSEDDKKQSKK----GTEEKKKPSDFKKK-----------VIKMEQQYESSSDGTEKLP 1020

Query: 240  EESE-----------ERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAE 288
            E  E           +  T   ++K ++ +  TS   +E+ +   K T         S +
Sbjct: 1021 EREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTG-----KGDSCD 1075

Query: 289  SSED 292
            SSED
Sbjct: 1076 SSED 1079



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 49/228 (21%), Positives = 83/228 (36%), Gaps = 27/228 (11%)

Query: 19   DAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNE 78
            +A N++  ESD     E  K+    +R  + K+  S       DG   E ++   +   E
Sbjct: 1315 EAKNQVNSESD--SDSEESKKPRYRHRLLRHKLTVS-------DGESGEEKKTKPKEHKE 1365

Query: 79   ISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSSDQQDITNGKKTS 138
            + G            N++    E +    +  SG  E   E  E++   +    + KK  
Sbjct: 1366 VKGR-----------NRRKVSSEDSEDSDFQESGVSE---EVSESEDEQRPRTRSAKKAE 1411

Query: 139  PQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTR 198
             +       S K KK ++  K ++   S  K    ++E      +   E  EE       
Sbjct: 1412 LE---ENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDEND 1468

Query: 199  KGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERD 246
              K P K +KK R K LK   L  E ++     ++     +E   ER+
Sbjct: 1469 DSKSPGKGRKKIR-KILKDDKLRTETQNALKEEEERRKRIAERERERE 1515



 Score = 38.9 bits (89), Expect = 0.005
 Identities = 35/179 (19%), Positives = 67/179 (37%), Gaps = 31/179 (17%)

Query: 119  EEFETDSSDQQDITNGKKTSPQVKSSTHESRKHKKS----KKSHKKKQKKRSHKKQKKSK 174
            EE +   + + D  + +   P+ +   H   +HK +    +   +KK K + HK+ K   
Sbjct: 1314 EEAKNQVNSESDSDSEESKKPRYR---HRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRN 1370

Query: 175  KEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDS 234
            +          S+F E    SG  +     + +++ R +S KK  L              
Sbjct: 1371 RRKVSSEDSEDSDFQE----SGVSEEVSESEDEQRPRTRSAKKAEL-------------- 1412

Query: 235  ASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD 293
                  E  +R  K+ K+++R K    S + N+      +    +   +E   E  E+D
Sbjct: 1413 ------EENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEED 1465



 Score = 35.8 bits (81), Expect = 0.046
 Identities = 29/172 (16%), Positives = 61/172 (35%), Gaps = 1/172 (0%)

Query: 122  ETDSSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDIT 181
            + D S   +   GKK + +         + K    S      + S K + + +     +T
Sbjct: 1287 DEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLT 1346

Query: 182  ADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEE 241
                    E+       K  +   R+K S + S              S S+D     +  
Sbjct: 1347 VSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRS 1406

Query: 242  SEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD 293
            +++ + ++ +R  ++KK    +   E     NK +N +   +E+  E  E++
Sbjct: 1407 AKKAELEENQRSYKQKKKRRRIKVQEDSSSENK-SNSEEEEEEKEEEEEEEE 1457



 Score = 35.4 bits (80), Expect = 0.060
 Identities = 58/298 (19%), Positives = 108/298 (36%), Gaps = 37/298 (12%)

Query: 26   EESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEIS-GTLE 84
            E++   K R   K+     +  KR  L +S+ R ++D     S       +N I  G+ +
Sbjct: 1163 EDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSD 1222

Query: 85   DDFLKAKSWNKKFYDYEANMPDRWGHSGYKEL-YPEEFETDSSDQQDITNGKKTSPQVK- 142
            +  +K  + N     +          +  K +    + + D +D ++    K    ++K 
Sbjct: 1223 EQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKA 1282

Query: 143  --SSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEET-------- 192
              SS  +     + ++  K+  K+       +  K   +  +DS SE S++         
Sbjct: 1283 NLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLR 1342

Query: 193  -------GASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEER 245
                   G SG  K  +P + K+   +   K       +  ++  SD   S  SEE  E 
Sbjct: 1343 HKLTVSDGESGEEKKTKPKEHKEVKGRNRRKV------SSEDSEDSDFQESGVSEEVSES 1396

Query: 246  DTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATD----------ERSAESSEDD 293
            + ++  R +  KKA     N    ++  KR   KV  D          E   E  E++
Sbjct: 1397 EDEQRPRTRSAKKAELE-ENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEE 1453



 Score = 34.7 bits (78), Expect = 0.10
 Identities = 40/200 (20%), Positives = 79/200 (39%), Gaps = 31/200 (15%)

Query: 110 HSGYKELYPEEFETDSSDQQDITNGKKTSPQVKSSTHESRKHKKSKKS--HKKKQKKRSH 167
           H+ +K LY  + +    D+      +K       S  +++K K +K S   KKK++ +S 
Sbjct: 758 HTNHKTLYDLKTQAGKDDK----GKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSE 813

Query: 168 KKQKKSKKE-------------ATDITADSSSEFSEETGASGTRKG--KQPHKRKKKSRK 212
                S+ E              T     ++ +F        ++KG   Q HK  K S++
Sbjct: 814 SSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQE 873

Query: 213 KSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTK-RKKREKKAHTSVANNEIQER 271
            S         ++      +    SS+E + ++DT   + R +  KK   S + + + + 
Sbjct: 874 GS---------SDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKL 924

Query: 272 TNKRTNWKVATDERSAESSE 291
           + K  ++      + AE+ E
Sbjct: 925 SGKEQSFTSLEVRKVAETKE 944



 Score = 28.5 bits (62), Expect = 7.3
 Identities = 16/64 (25%), Positives = 33/64 (51%), Gaps = 7/64 (10%)

Query: 230 HSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAES 289
           +S +  +SSSE+S+   + ++KRK        S+    ++    K  + +   ++ S E+
Sbjct: 59  NSKEEGTSSSEKSKSSGSSRSKRK-------PSIVTKYVESDDEKPLDDETVNEDASNEN 111

Query: 290 SEDD 293
           SE+D
Sbjct: 112 SEND 115


>gi|33457330 tetratricopeptide repeat domain 14 isoform a [Homo
           sapiens]
          Length = 770

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 51/244 (20%), Positives = 105/244 (43%), Gaps = 47/244 (19%)

Query: 16  RHTDAHNKIQEESDMWKIRELEKQMEDAY---------RGTKRKMLPSSSSRMRSDGFDE 66
           RH DA N+        K  E++KQ  +A          +G+  K +      + +     
Sbjct: 322 RHVDAMNEYN------KALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPTHR 375

Query: 67  ESQRYYWRPKNEISGTLEDD--FLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETD 124
            +++Y  +   E  G LE++  FL A+S+ KK    +                 E F+  
Sbjct: 376 NARKYLCQTLVERGGQLEEEEKFLNAESYYKKALALD-----------------ETFKDA 418

Query: 125 SSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKR----SHKKQKKSKKEATDI 180
               Q +    + S +++    E  + +K+KK     +K R      K+ KK ++++T  
Sbjct: 419 EDALQKLHKYMQKSLELREKQAEKEEKQKTKKIETSAEKLRKLLKEEKRLKKKRRKSTSS 478

Query: 181 TADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSE 240
           ++ SS++ S  + +S +  G + HK+ K++R +S         + S+  HS  ++S+  +
Sbjct: 479 SSVSSADESVSSSSSSSSSGHKRHKKHKRNRSES---------SRSSRRHSSRASSNQID 529

Query: 241 ESEE 244
           ++ +
Sbjct: 530 QNRK 533


>gi|50409738 SRp25 nuclear protein isoform 3 [Homo sapiens]
          Length = 352

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 32/125 (25%), Positives = 59/125 (47%), Gaps = 6/125 (4%)

Query: 151 HKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKS 210
           H  S+K  + + + R    +K+ KK   D + + S+  S+   AS     ++  K+K + 
Sbjct: 126 HVGSRKRSRSRSRSRGRGSEKRKKKSRKDTSRNCSASTSQGRKASTAPGAEERSKQKARR 185

Query: 211 RKKSLKKPALFLEAESNTSHSDDSASSSS------EESEERDTKKTKRKKREKKAHTSVA 264
           R +S    +    + S++S S  S+SSS       +  ++R  KK KRKK +KK      
Sbjct: 186 RTRSSSSSSSSSSSSSSSSSSSSSSSSSDGRKKRGKYKDKRRKKKKKRKKLKKKGKEKAE 245

Query: 265 NNEIQ 269
             +++
Sbjct: 246 AQQVE 250



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 32/115 (27%), Positives = 55/115 (47%), Gaps = 11/115 (9%)

Query: 144 STHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQP 203
           S   SR   +S+    +K+KK+S K   +      + +A +S      T      + KQ 
Sbjct: 129 SRKRSRSRSRSRGRGSEKRKKKSRKDTSR------NCSASTSQGRKASTAPGAEERSKQK 182

Query: 204 HKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKK 258
            +R+ +S   S         + S++S S  S+SSSS+  ++R   K KR+K++KK
Sbjct: 183 ARRRTRSSSSSSSS-----SSSSSSSSSSSSSSSSSDGRKKRGKYKDKRRKKKKK 232



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 32/137 (23%), Positives = 63/137 (45%), Gaps = 7/137 (5%)

Query: 126 SDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSS 185
           S+++   + K TS    +ST + RK   +  + ++ ++K   + +  S   ++  ++ SS
Sbjct: 144 SEKRKKKSRKDTSRNCSASTSQGRKASTAPGAEERSKQKARRRTRSSSSSSSSSSSSSSS 203

Query: 186 SEFSEETGASGTRKGKQPHKRKKKSRKKSLKK-------PALFLEAESNTSHSDDSASSS 238
           S  S  + +S  RK +  +K K++ +KK  KK        A   + E+    S D    S
Sbjct: 204 SSSSSSSSSSDGRKKRGKYKDKRRKKKKKRKKLKKKGKEKAEAQQVEALPGPSLDQWHRS 263

Query: 239 SEESEERDTKKTKRKKR 255
           + E E+      ++K R
Sbjct: 264 AGEEEDGPVLTDEQKSR 280



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 32/153 (20%), Positives = 62/153 (40%), Gaps = 9/153 (5%)

Query: 123 TDSSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITA 182
           + SS     ++   +S    SS    ++ K   K  KKK+K++  KK+ K K EA  + A
Sbjct: 192 SSSSSSSSSSSSSSSSSSSSSSDGRKKRGKYKDKRRKKKKKRKKLKKKGKEKAEAQQVEA 251

Query: 183 DSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEES 242
                  +   ++G  +       ++KSR +++K           T    D+  S   + 
Sbjct: 252 LPGPSLDQWHRSAGEEEDGPVLTDEQKSRIQAMK---------PMTKEEWDARQSIIRKV 302

Query: 243 EERDTKKTKRKKREKKAHTSVANNEIQERTNKR 275
            + +T +T+  K + +    +   E     NK+
Sbjct: 303 VDPETGRTRLIKGDGEVLEEIVTKERHREINKQ 335


>gi|104526627 triadin [Homo sapiens]
          Length = 729

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 38/156 (24%), Positives = 73/156 (46%), Gaps = 26/156 (16%)

Query: 119 EEFETDSSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEAT 178
           E+ E D  D +D   G+   P ++       K +K +K  +K Q K +HK+++K K++  
Sbjct: 117 EDEEDDDGD-EDTDKGEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHKEKEKGKEK-- 173

Query: 179 DITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSS 238
                              R+ ++P   KK + K+ ++K     + E+ T   +   + +
Sbjct: 174 ------------------VREKEKP--EKKATHKEKIEKKE---KPETKTLAKEQKKAKT 210

Query: 239 SEESEERDTKKTKRKKREKKAHTSVANNEIQERTNK 274
           +E+SEE+  K+ K  K+EK   T+    E+Q+  +K
Sbjct: 211 AEKSEEKTKKEVKGGKQEKVKQTAAKVKEVQKTPSK 246



 Score = 42.0 bits (97), Expect = 6e-04
 Identities = 45/166 (27%), Positives = 68/166 (40%), Gaps = 16/166 (9%)

Query: 138 SPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGT 197
           SP ++    E +K +K   S  KK++K   KK K  K+ A D+      + SE     GT
Sbjct: 306 SPALEEKEGEKKKAEKKVTSETKKKEKEDIKK-KSEKETAIDVEKKEPGKASETK--QGT 362

Query: 198 RKGKQPHKRKKKSRK---KSLKKPALF-----LEAESNTSHSDDSASSSSEESEERDTK- 248
            K       KK  +K   K  KKPA        + E    H + + S   E S   D + 
Sbjct: 363 VKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQV 422

Query: 249 --KTKRKKREKKAHT--SVANNEIQERTNKRTNWKVATDERSAESS 290
             KT+R K E  A +       + +E+T K    ++  ++    SS
Sbjct: 423 KAKTERAKEEIGAVSIKKAVPGKKEEKTTKTVEQEIRKEKSGKTSS 468



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 32/137 (23%), Positives = 62/137 (45%), Gaps = 15/137 (10%)

Query: 116 LYPEEFETDSSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKK--QKKS 173
           L  +E   D +++Q+    K    Q K +  E  K K+  +  +K +KK +HK+  +KK 
Sbjct: 138 LRKKEIHKDKTEKQEKPERKI---QTKVTHKEKEKGKEKVREKEKPEKKATHKEKIEKKE 194

Query: 174 KKEATDITAD----SSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTS 229
           K E   +  +     ++E SEE      + GKQ   ++  ++ K ++K        S   
Sbjct: 195 KPETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTAAKVKEVQK------TPSKPK 248

Query: 230 HSDDSASSSSEESEERD 246
             +D   ++  + E++D
Sbjct: 249 EKEDKEKAAVSKHEQKD 265



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 36/162 (22%), Positives = 67/162 (41%), Gaps = 10/162 (6%)

Query: 135 KKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGA 194
           KK  P+ K+   E +K K ++KS +K +K+    KQ+K K+ A  +     +    +   
Sbjct: 192 KKEKPETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTAAKVKEVQKTPSKPKEKE 251

Query: 195 SGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSD--------DSASSSSEESEERD 246
              +     H++K +          +F+  +     S         + AS  +  S   +
Sbjct: 252 DKEKAAVSKHEQKDQYAFCRYMID-IFVHGDLKPGQSPAIPPPLPTEQASRPTPASPALE 310

Query: 247 TKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAE 288
            K+ ++KK EKK  TS    + +E   K++  + A D    E
Sbjct: 311 EKEGEKKKAEKKV-TSETKKKEKEDIKKKSEKETAIDVEKKE 351



 Score = 38.1 bits (87), Expect = 0.009
 Identities = 39/167 (23%), Positives = 76/167 (45%), Gaps = 15/167 (8%)

Query: 135 KKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGA 194
           KK + + K    E  K K  K++    +KK    K  ++K+    I A ++++  E+   
Sbjct: 321 KKVTSETKKKEKEDIKKKSEKETAIDVEKKEP-GKASETKQGTVKIAAQAAAKKDEK--K 377

Query: 195 SGTRKGKQP-----HKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEER---- 245
             ++K K+P      K KK+ +K+   +PA   + E +   SD    + +E ++E     
Sbjct: 378 EDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKSPKKEHSVP-SDKQVKAKTERAKEEIGAV 436

Query: 246 DTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSED 292
             KK    K+E+K  T     EI++  + +T+  +  D+   +  E+
Sbjct: 437 SIKKAVPGKKEEKT-TKTVEQEIRKEKSGKTS-SILKDKEPIKGKEE 481



 Score = 33.1 bits (74), Expect = 0.30
 Identities = 40/165 (24%), Positives = 65/165 (39%), Gaps = 15/165 (9%)

Query: 135 KKTSPQVKSSTHE--SRKHKKSKKSHKKKQKKRSH-KKQKKSKKEATDITADSSSEFSEE 191
           +K  PQ+K       S K +  K+   K +K  SH K ++K  K+   +T        E+
Sbjct: 520 EKPEPQIKKEAKPAISEKVQIHKQDIVKPEKTVSHGKPEEKVLKQVKAVTI-------EK 572

Query: 192 TGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTK 251
           T      K  +  +R+  S K    KP     +E   S    +  S  E  E+ D K  +
Sbjct: 573 TAKPKPTKKAEHREREPPSIKTDKPKPTPKGTSEVTESGKKKTEISEKESKEKADMKHLR 632

Query: 252 RKK----REKKAHTSVANNEIQERTNKRTNWKVATDERSAESSED 292
            +K    +E     +V   E   R +K     V   +++ E +ED
Sbjct: 633 EEKVSTRKESLQLHNVTKAEKPARVSKDVE-DVPASKKAKEGTED 676



 Score = 31.2 bits (69), Expect = 1.1
 Identities = 40/180 (22%), Positives = 72/180 (40%), Gaps = 32/180 (17%)

Query: 119 EEFETDSSDQQDITNGK--KTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKE 176
           +E +T  + +Q+I   K  KTS  +K    E  K K+ K     K+K+   KK +K  K 
Sbjct: 446 KEEKTTKTVEQEIRKEKSGKTSSILKDK--EPIKGKEEKVPASLKEKEPETKKDEKMSK- 502

Query: 177 ATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPAL-----FLEAESNTSHS 231
                  +  E   +      +K ++P  + KK  K ++ +         ++ E   SH 
Sbjct: 503 -------AGKEVKPKPPQLQGKKEEKPEPQIKKEAKPAISEKVQIHKQDIVKPEKTVSHG 555

Query: 232 DD--------SASSSSEESEERDTKKTKRKKRE-------KKAHTSVANNEIQERTNKRT 276
                      A +  + ++ + TKK + ++RE       K   T    +E+ E   K+T
Sbjct: 556 KPEEKVLKQVKAVTIEKTAKPKPTKKAEHREREPPSIKTDKPKPTPKGTSEVTESGKKKT 615


>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
           containing B [Homo sapiens]
          Length = 546

 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 52/246 (21%), Positives = 107/246 (43%), Gaps = 24/246 (9%)

Query: 25  QEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRS-DGFDEESQRYYWRPKNEISGTL 83
           + E +  + R +++ +E     ++ +    S SR R  D  D + +R     +NE     
Sbjct: 310 EREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDRER---EKENERGRRR 366

Query: 84  EDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSSDQQ---DITNGKKTSPQ 140
           + D+ K +  N++  + E +           E+  ++ + D  D++   D  + KK    
Sbjct: 367 DRDYDKERG-NEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKH 425

Query: 141 VKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTR-- 198
            +S + E RKH+   +S    ++ RS  K+K SK +      + S E S +   SG++  
Sbjct: 426 SRSRSRE-RKHRSRSRSRNAGKRSRSRSKEKSSKHK------NESKEKSNKRSRSGSQGR 478

Query: 199 -------KGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTK 251
                  K ++    K+KSRK+S  K        S++    D       +S E+++++ +
Sbjct: 479 TDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQ 538

Query: 252 RKKREK 257
            K +++
Sbjct: 539 HKNKDE 544



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 34/152 (22%), Positives = 71/152 (46%), Gaps = 7/152 (4%)

Query: 142 KSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDIT-ADSSSEFSEETGASGTRKG 200
           K   +E  K ++  +   K+Q+ R   ++KK K++  D    D   +  +E   S +R  
Sbjct: 372 KERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSR 431

Query: 201 KQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAH 260
           ++ H  + +SR ++  K +     E ++ H ++S   S++ S      +T   ++ KK  
Sbjct: 432 ERKH--RSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKRE 489

Query: 261 TSVANNEIQERTNKRTNWKVATDERSAESSED 292
            S +    +E++ KR+  K  + +R    S+D
Sbjct: 490 HSPS----KEKSRKRSRSKERSHKRDHSDSKD 517



 Score = 48.1 bits (113), Expect = 9e-06
 Identities = 52/243 (21%), Positives = 98/243 (40%), Gaps = 26/243 (10%)

Query: 34  RELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEISGTLEDDFLKAKSW 93
           RELE++ E      + K       R RS     E +R   R ++       D     +  
Sbjct: 293 RELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRD-----RKG 347

Query: 94  NKKFYDYEANMPDRWGHSGYKELYPEEFETDSSDQQDITNGKKTSPQVKSSTHESRKHKK 153
           +++  D E    +  G    ++ Y +E   +   +++ +  +++  Q      E +KHK+
Sbjct: 348 DRRDRDREREKENERGRRRDRD-YDKERGNEREKERERSR-ERSKEQRSRGEVEEKKHKE 405

Query: 154 SKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGA-SGTRKGKQPHKRKKKSRK 212
            K   + +  KR  KK+KK  +  +      S   S   G  S +R  ++  K K +S++
Sbjct: 406 DKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKE 465

Query: 213 KSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERT 272
           KS K+      + S +    DS   S +       +K++++ R K            ER+
Sbjct: 466 KSNKR------SRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSK------------ERS 507

Query: 273 NKR 275
           +KR
Sbjct: 508 HKR 510



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 36/165 (21%), Positives = 70/165 (42%), Gaps = 6/165 (3%)

Query: 127 DQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSS 186
           DQQ  T  +K     K    E  +H + ++S   ++     +  ++S+  +       SS
Sbjct: 230 DQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSS 289

Query: 187 EFSEETGASGTRKGKQPHKRKKKSRKKSLKKP-ALFLEAESNTSHSDDSASSSSEESEER 245
            F  E       K +Q  +R+ K R+K  ++  ++    E   S S +   S S   + +
Sbjct: 290 SFDREL---EREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRK 346

Query: 246 DTKKTKRKKREKKAHTSVANNE--IQERTNKRTNWKVATDERSAE 288
             ++ + ++REK+       +    +ER N+R   +  + ERS E
Sbjct: 347 GDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKE 391



 Score = 32.3 bits (72), Expect = 0.51
 Identities = 42/200 (21%), Positives = 80/200 (40%), Gaps = 31/200 (15%)

Query: 34  RELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEIS-GTLEDDFLKAKS 92
           RE EK+ E   RG +R        + R +  ++E +R   R K + S G +E+   K   
Sbjct: 354 REREKENE---RGRRRDR---DYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDK 407

Query: 93  WNKKFYDYEANMPDRWGHSGYKELYPEEFETDSSDQQDITNGKKTSPQVKSSTHESRKHK 152
            +++  D + +      HS  +    E      S  ++     ++  + KSS H++   +
Sbjct: 408 DDRRHRDDKRDSKKEKKHSRSRSR--ERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKE 465

Query: 153 KS-------------------KKSH---KKKQKKRSHKKQKKSKKEATDITADSSSEFSE 190
           KS                   K+ H   K+K +KRS  K++  K++ +D    S      
Sbjct: 466 KSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRR 525

Query: 191 ETGASGTRKGKQPHKRKKKS 210
            + +      ++ HK K ++
Sbjct: 526 RSQSIEQESQEKQHKNKDET 545



 Score = 31.2 bits (69), Expect = 1.1
 Identities = 23/92 (25%), Positives = 42/92 (45%), Gaps = 4/92 (4%)

Query: 205 KRKKKSRKKSLKKPALFLEAESNTSHSDDSASSS----SEESEERDTKKTKRKKREKKAH 260
           +R+ +S ++SL        + S + H +   SSS     E  +ER   + + K+REK+  
Sbjct: 257 RRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERR 316

Query: 261 TSVANNEIQERTNKRTNWKVATDERSAESSED 292
            S + +   ER   R+  +  +  RS +   D
Sbjct: 317 RSRSIDRGLERRRSRSRERHRSRSRSRDRKGD 348


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.302    0.118    0.321 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,967,817
Number of Sequences: 37866
Number of extensions: 507022
Number of successful extensions: 12400
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 479
Number of HSP's successfully gapped in prelim test: 720
Number of HSP's that attempted gapping in prelim test: 4328
Number of HSP's gapped (non-prelim): 4439
length of query: 293
length of database: 18,247,518
effective HSP length: 101
effective length of query: 192
effective length of database: 14,423,052
effective search space: 2769225984
effective search space used: 2769225984
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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