Search of human proteins with 4557701

Search of human proteins with 4557701

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4557701 keratin 17 [Homo sapiens]
         (432 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4557701 keratin 17 [Homo sapiens]                                  837   0.0  
gi|15431310 keratin 14 [Homo sapiens]                                 639   0.0  
gi|24430192 keratin 16 [Homo sapiens]                                 580   e-165
gi|24430190 keratin 15 [Homo sapiens]                                 516   e-146
gi|131412228 keratin 13 isoform b [Homo sapiens]                      494   e-140
gi|131412225 keratin 13 isoform a [Homo sapiens]                      494   e-140
gi|24234699 keratin 19 [Homo sapiens]                                 494   e-140
gi|4557699 keratin 12 [Homo sapiens]                                  465   e-131
gi|195972866 keratin 10 [Homo sapiens]                                463   e-130
gi|4504927 keratin 36 [Homo sapiens]                                  432   e-121
gi|192807292 keratin 24 [Homo sapiens]                                428   e-120
gi|153945736 keratin 27 [Homo sapiens]                                421   e-118
gi|114431246 keratin 25D [Homo sapiens]                               414   e-116
gi|94538345 keratin 35 [Homo sapiens]                                 407   e-114
gi|27894337 keratin 20 [Homo sapiens]                                 398   e-111
gi|31559829 keratin 25 [Homo sapiens]                                 385   e-107
gi|55956899 keratin 9 [Homo sapiens]                                  375   e-104
gi|14917117 keratin 33A [Homo sapiens]                                373   e-103
gi|10337581 type I hair keratin 3B [Homo sapiens]                     373   e-103
gi|14917115 keratin 31 [Homo sapiens]                                 373   e-103
gi|14917119 keratin 34 [Homo sapiens]                                 372   e-103
gi|116488398 keratin 32 [Homo sapiens]                                365   e-101
gi|31559815 keratin 26 [Homo sapiens]                                 365   e-101
gi|125490370 type I hair keratin KA36 [Homo sapiens]                  338   7e-93
gi|40354195 keratin 18 [Homo sapiens]                                 329   3e-90
gi|4557888 keratin 18 [Homo sapiens]                                  329   3e-90
gi|148277620 type I hair keratin KA35 [Homo sapiens]                  328   8e-90
gi|15431318 keratin 38 [Homo sapiens]                                 325   6e-89
gi|55770882 keratin 37 [Homo sapiens]                                 323   2e-88
gi|27894339 keratin 23 [Homo sapiens]                                 319   3e-87

>gi|4557701 keratin 17 [Homo sapiens]
          Length = 432

 Score =  837 bits (2163), Expect = 0.0
 Identities = 432/432 (100%), Positives = 432/432 (100%)

Query: 1   MTTSIRQFTSSSSIKGSSGLGGGSSRTSCRLSGGLGAGSCRLGSAGGLGSTLGGSSYSSC 60
           MTTSIRQFTSSSSIKGSSGLGGGSSRTSCRLSGGLGAGSCRLGSAGGLGSTLGGSSYSSC
Sbjct: 1   MTTSIRQFTSSSSIKGSSGLGGGSSRTSCRLSGGLGAGSCRLGSAGGLGSTLGGSSYSSC 60

Query: 61  YSFGSGGGYGSSFGGVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVKIRDWY 120
           YSFGSGGGYGSSFGGVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVKIRDWY
Sbjct: 61  YSFGSGGGYGSSFGGVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVKIRDWY 120

Query: 121 QRQAPGPARDYSQYYRTIEELQNKILTATVDNANILLQIDNARLAADDFRTKFETEQALR 180
           QRQAPGPARDYSQYYRTIEELQNKILTATVDNANILLQIDNARLAADDFRTKFETEQALR
Sbjct: 121 QRQAPGPARDYSQYYRTIEELQNKILTATVDNANILLQIDNARLAADDFRTKFETEQALR 180

Query: 181 LSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGEINVE 240
           LSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGEINVE
Sbjct: 181 LSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGEINVE 240

Query: 241 MDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQSGKSEI 300
           MDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQSGKSEI
Sbjct: 241 MDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQSGKSEI 300

Query: 301 SELRRTMQALEIELQSQLSMKASLEGNLAETENRYCVQLSQIQGLIGSVEEQLAQLRCEM 360
           SELRRTMQALEIELQSQLSMKASLEGNLAETENRYCVQLSQIQGLIGSVEEQLAQLRCEM
Sbjct: 301 SELRRTMQALEIELQSQLSMKASLEGNLAETENRYCVQLSQIQGLIGSVEEQLAQLRCEM 360

Query: 361 EQQNQEYKILLDVKTRLEQEIATYRRLLEGEDAHLTQYKKEPVTTRQVRTIVEEVQDGKV 420
           EQQNQEYKILLDVKTRLEQEIATYRRLLEGEDAHLTQYKKEPVTTRQVRTIVEEVQDGKV
Sbjct: 361 EQQNQEYKILLDVKTRLEQEIATYRRLLEGEDAHLTQYKKEPVTTRQVRTIVEEVQDGKV 420

Query: 421 ISSREQVHQTTR 432
           ISSREQVHQTTR
Sbjct: 421 ISSREQVHQTTR 432


>gi|15431310 keratin 14 [Homo sapiens]
          Length = 472

 Score =  639 bits (1647), Expect = 0.0
 Identities = 346/470 (73%), Positives = 376/470 (80%), Gaps = 40/470 (8%)

Query: 1   MTTSIRQFTSSSSIKGSSGLGGGSSRTSCRLSGGLGAGSCRL-----------------G 43
           MTT  RQFTSSSS+KGS G+GGG    S R+S  L  GSCR                  G
Sbjct: 1   MTTCSRQFTSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSSRFSSG 60

Query: 44  SAGGLGSTLGGSSYSSCYSFGSG--------------GGYGSSFGGVDGLLAGGEKATMQ 89
            A GLG   GG   SS  SFGSG              GG+G  F G DGLL G EK TMQ
Sbjct: 61  GAYGLGGGYGGGFSSSSSSFGSGFGGGYGGGLGAGLGGGFGGGFAGGDGLLVGSEKVTMQ 120

Query: 90  NLNDRLASYLDKVRALEEANTELEVKIRDWYQRQAPGPARDYSQYYRTIEELQNKILTAT 149
           NLNDRLASYLDKVRALEEAN +LEVKIRDWYQRQ P   +DYS Y++TIE+L+NKILTAT
Sbjct: 121 NLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPAEIKDYSPYFKTIEDLRNKILTAT 180

Query: 150 VDNANILLQIDNARLAADDFRTKFETEQALRLSVEADINGLRRVLDELTLARADLEMQIE 209
           VDNAN+LLQIDNARLAADDFRTK+ETE  LR+SVEADINGLRRVLDELTLARADLEMQIE
Sbjct: 181 VDNANVLLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLDELTLARADLEMQIE 240

Query: 210 NLKEELAYLKKNHEEEMNALRGQVGGEINVEMDAAPGVDLSRILNEMRDQYEKMAEKNRK 269
           +LKEELAYLKKNHEEEMNALRGQVGG++NVEMDAAPGVDLSRILNEMRDQYEKMAEKNRK
Sbjct: 241 SLKEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEKNRK 300

Query: 270 DAEDWFFSKTEELNREVATNSELVQSGKSEISELRRTMQALEIELQSQLSMKASLEGNLA 329
           DAE+WFF+KTEELNREVATNSELVQSGKSEISELRRTMQ LEIELQSQLSMKASLE +L 
Sbjct: 301 DAEEWFFTKTEELNREVATNSELVQSGKSEISELRRTMQNLEIELQSQLSMKASLENSLE 360

Query: 330 ETENRYCVQLSQIQGLIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLE 389
           ET+ RYC+QL+QIQ +IGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLE
Sbjct: 361 ETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLE 420

Query: 390 GEDAHLT-------QYKKEPVT--TRQVRTIVEEVQDGKVISSREQVHQT 430
           GEDAHL+             VT  +RQ+RT V +V DGKV+S+ EQV +T
Sbjct: 421 GEDAHLSSSQFSSGSQSSRDVTSSSRQIRTKVMDVHDGKVVSTHEQVLRT 470


>gi|24430192 keratin 16 [Homo sapiens]
          Length = 473

 Score =  580 bits (1494), Expect = e-165
 Identities = 311/446 (69%), Positives = 350/446 (78%), Gaps = 37/446 (8%)

Query: 1   MTTSIRQFTSSSSIKGSSGLGGGSSRTSCRLSGGLGAGSCRL----------------GS 44
           MTT  RQFTSSSS+KGS G+GGG    S R+S  L  GSCR                 G 
Sbjct: 1   MTTCSRQFTSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSRFSSGG 60

Query: 45  AGGLGSTLGGSSYSSCYSFGSG------------------GGYGSSFGGVDGLLAGGEKA 86
           A GLG   GG  +SS  SFGSG                   G+G  F G DGLL G EK 
Sbjct: 61  ACGLGGGYGGG-FSSSSSFGSGFGGGYGGGLGAGFGGGLGAGFGGGFAGGDGLLVGSEKV 119

Query: 87  TMQNLNDRLASYLDKVRALEEANTELEVKIRDWYQRQAPGPARDYSQYYRTIEELQNKIL 146
           TMQNLNDRLASYLDKVRALEEAN +LEVKIRDWYQRQ P   +DYS Y++TIE+L+NKI+
Sbjct: 120 TMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPSEIKDYSPYFKTIEDLRNKII 179

Query: 147 TATVDNANILLQIDNARLAADDFRTKFETEQALRLSVEADINGLRRVLDELTLARADLEM 206
            AT++NA  +LQIDNARLAADDFRTK+E E ALR +VEAD+NGLRRVLDELTLAR DLEM
Sbjct: 180 AATIENAQPILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRRVLDELTLARTDLEM 239

Query: 207 QIENLKEELAYLKKNHEEEMNALRGQVGGEINVEMDAAPGVDLSRILNEMRDQYEKMAEK 266
           QIE LKEELAYL+KNHEEEM ALRGQ GG++NVEMDAAPGVDLSRILNEMRDQYE+MAEK
Sbjct: 240 QIEGLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEK 299

Query: 267 NRKDAEDWFFSKTEELNREVATNSELVQSGKSEISELRRTMQALEIELQSQLSMKASLEG 326
           NR+DAE WF SKTEELN+EVA+NSELVQS +SE++ELRR +Q LEIELQSQLSMKASLE 
Sbjct: 300 NRRDAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEIELQSQLSMKASLEN 359

Query: 327 NLAETENRYCVQLSQIQGLIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRR 386
           +L ET+ RYC+QLSQIQGLIGSVEEQLAQLRCEMEQQ+QEY+ILLDVKTRLEQEIATYRR
Sbjct: 360 SLEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDVKTRLEQEIATYRR 419

Query: 387 LLEGEDAHLT--QYKKEPVTTRQVRT 410
           LLEGEDAHL+  Q   +  ++R+V T
Sbjct: 420 LLEGEDAHLSSQQASGQSYSSREVFT 445


>gi|24430190 keratin 15 [Homo sapiens]
          Length = 456

 Score =  516 bits (1330), Expect = e-146
 Identities = 282/459 (61%), Positives = 332/459 (72%), Gaps = 38/459 (8%)

Query: 1   MTTSIRQFTSS----------SSIKGSSGLGGGS----------SRTSCRL-----SGGL 35
           MTT+  Q +SS          S + G  G GGGS          S +S R       GG 
Sbjct: 1   MTTTFLQTSSSTFGGGSTRGGSLLAGGGGFGGGSLSGGGGSRSISASSARFVSSGSGGGY 60

Query: 36  GAGSCRLGSAGGLGSTLGGSSYSSCYSFGSGGGYGSSFGGVDG-LLAGGEKATMQNLNDR 94
           G G    G  GG GS  GG      +  G GGG+G  FGG DG LL+G EK TMQNLNDR
Sbjct: 61  GGGMRVCGFGGGAGSVFGGG-----FGGGVGGGFGGGFGGGDGGLLSGNEKITMQNLNDR 115

Query: 95  LASYLDKVRALEEANTELEVKIRDWYQRQAP-GPARDYSQYYRTIEELQNKILTATVDNA 153
           LASYLDKVRALEEAN +LEVKI DWYQ+Q P  P  DYSQY++TIEEL++KI+  T+DN+
Sbjct: 116 LASYLDKVRALEEANADLEVKIHDWYQKQTPTSPECDYSQYFKTIEELRDKIMATTIDNS 175

Query: 154 NILLQIDNARLAADDFRTKFETEQALRLSVEADINGLRRVLDELTLARADLEMQIENLKE 213
            ++L+IDNARLAADDFR K+E E ALR  VEADINGLRRVLDELTLAR DLEMQIE L E
Sbjct: 176 RVILEIDNARLAADDFRLKYENELALRQGVEADINGLRRVLDELTLARTDLEMQIEGLNE 235

Query: 214 ELAYLKKNHEEEMNALRGQVGGEINVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAED 273
           ELAYLKKNHEEEM     Q+ G++NVEMDAAPGVDL+R+L EMR+QYE MAEKNR+D E 
Sbjct: 236 ELAYLKKNHEEEMKEFSSQLAGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEKNRRDVEA 295

Query: 274 WFFSKTEELNREVATNSELVQSGKSEISELRRTMQALEIELQSQLSMKASLEGNLAETEN 333
           WFFSKTEELN+EVA+N+E++Q+ K+EI++LRRTMQ LEIELQSQLSMKA LE +LAETE 
Sbjct: 296 WFFSKTEELNKEVASNTEMIQTSKTEITDLRRTMQELEIELQSQLSMKAGLENSLAETEC 355

Query: 334 RYCVQLSQIQGLIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGEDA 393
           RY  QL QIQGLIG +E QL++LRCEME QNQEYK+LLD+KTRLEQEIATYR LLEG+DA
Sbjct: 356 RYATQLQQIQGLIGGLEAQLSELRCEMEAQNQEYKMLLDIKTRLEQEIATYRSLLEGQDA 415

Query: 394 HLTQYKKEPV------TTRQVRTIVEEVQDGKVISSREQ 426
            +              ++      VEE  DG+V+SS ++
Sbjct: 416 KMAGIGIREASSGGGGSSSNFHINVEESVDGQVVSSHKR 454


>gi|131412228 keratin 13 isoform b [Homo sapiens]
          Length = 420

 Score =  494 bits (1273), Expect = e-140
 Identities = 266/423 (62%), Positives = 319/423 (75%), Gaps = 35/423 (8%)

Query: 4   SIRQFTSSSSIKGSSGLGGGSSRTSCRLSGGLGAGSCRL-----GSAGGLGSTLG----- 53
           S+R  +SS+S  G  G GGGS    C+L GG G  +C       GSAGG G  +      
Sbjct: 2   SLRLQSSSASYGG--GFGGGS----CQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGG 55

Query: 54  --GSSYSSCYSFGSGGGYGSSFGG----------VD------GLLAGGEKATMQNLNDRL 95
             GS +   Y  G GGGYG   GG          VD      GLL G EK TMQNLNDRL
Sbjct: 56  GAGSGFGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACDGGLLTGNEKITMQNLNDRL 115

Query: 96  ASYLDKVRALEEANTELEVKIRDWYQRQAPG-PARDYSQYYRTIEELQNKILTATVDNAN 154
           ASYL+KVRALEEAN +LEVKIRDW+ +Q+P  P RDYS YY+TIEEL++KILTAT++N  
Sbjct: 116 ASYLEKVRALEEANADLEVKIRDWHLKQSPASPERDYSPYYKTIEELRDKILTATIENNR 175

Query: 155 ILLQIDNARLAADDFRTKFETEQALRLSVEADINGLRRVLDELTLARADLEMQIENLKEE 214
           ++L+IDNARLAADDFR K+E E ALR SVEADINGLRRVLDELTL++ DLEMQIE+L EE
Sbjct: 176 VILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEE 235

Query: 215 LAYLKKNHEEEMNALRGQVGGEINVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEDW 274
           LAY+KKNHEEEM     QV G++NVEMDA PG+DL+R+L EMR+QYE MAE+NR+DAE+W
Sbjct: 236 LAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEW 295

Query: 275 FFSKTEELNREVATNSELVQSGKSEISELRRTMQALEIELQSQLSMKASLEGNLAETENR 334
           F +K+ ELN+EV+TN+ ++Q+ K+EI+ELRRT+Q LEIELQSQLSMKA LE  +AETE R
Sbjct: 296 FHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVAETECR 355

Query: 335 YCVQLSQIQGLIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGEDAH 394
           Y +QL QIQGLI S+E QL++LR EME QNQEYK+LLD+KTRLEQEIATYR LLEG+DA 
Sbjct: 356 YALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAK 415

Query: 395 LTQ 397
             Q
Sbjct: 416 KRQ 418


>gi|131412225 keratin 13 isoform a [Homo sapiens]
          Length = 458

 Score =  494 bits (1273), Expect = e-140
 Identities = 265/421 (62%), Positives = 319/421 (75%), Gaps = 35/421 (8%)

Query: 4   SIRQFTSSSSIKGSSGLGGGSSRTSCRLSGGLGAGSCRL-----GSAGGLGSTLG----- 53
           S+R  +SS+S  G  G GGGS    C+L GG G  +C       GSAGG G  +      
Sbjct: 2   SLRLQSSSASYGG--GFGGGS----CQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGG 55

Query: 54  --GSSYSSCYSFGSGGGYGSSFGG----------VD------GLLAGGEKATMQNLNDRL 95
             GS +   Y  G GGGYG   GG          VD      GLL G EK TMQNLNDRL
Sbjct: 56  GAGSGFGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACDGGLLTGNEKITMQNLNDRL 115

Query: 96  ASYLDKVRALEEANTELEVKIRDWYQRQAPG-PARDYSQYYRTIEELQNKILTATVDNAN 154
           ASYL+KVRALEEAN +LEVKIRDW+ +Q+P  P RDYS YY+TIEEL++KILTAT++N  
Sbjct: 116 ASYLEKVRALEEANADLEVKIRDWHLKQSPASPERDYSPYYKTIEELRDKILTATIENNR 175

Query: 155 ILLQIDNARLAADDFRTKFETEQALRLSVEADINGLRRVLDELTLARADLEMQIENLKEE 214
           ++L+IDNARLAADDFR K+E E ALR SVEADINGLRRVLDELTL++ DLEMQIE+L EE
Sbjct: 176 VILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEE 235

Query: 215 LAYLKKNHEEEMNALRGQVGGEINVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEDW 274
           LAY+KKNHEEEM     QV G++NVEMDA PG+DL+R+L EMR+QYE MAE+NR+DAE+W
Sbjct: 236 LAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEW 295

Query: 275 FFSKTEELNREVATNSELVQSGKSEISELRRTMQALEIELQSQLSMKASLEGNLAETENR 334
           F +K+ ELN+EV+TN+ ++Q+ K+EI+ELRRT+Q LEIELQSQLSMKA LE  +AETE R
Sbjct: 296 FHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVAETECR 355

Query: 335 YCVQLSQIQGLIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGEDAH 394
           Y +QL QIQGLI S+E QL++LR EME QNQEYK+LLD+KTRLEQEIATYR LLEG+DA 
Sbjct: 356 YALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAK 415

Query: 395 L 395
           +
Sbjct: 416 M 416


>gi|24234699 keratin 19 [Homo sapiens]
          Length = 400

 Score =  494 bits (1272), Expect = e-140
 Identities = 256/389 (65%), Positives = 312/389 (80%), Gaps = 6/389 (1%)

Query: 8   FTSSSSIKGSSGLGGGSSRTSCRLSGGLGAGSCRL-GSAGGLGSTLGGSSYSSCYSFGS- 65
           +  SS+     GLGGGS     R   G+   +  + G +GG G ++  + + S  S G+ 
Sbjct: 6   YRQSSATSSFGGLGGGS----VRFGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSSGAY 61

Query: 66  GGGYGSSFGGVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVKIRDWYQRQAP 125
           GGGYG      DGLLAG EK TMQNLNDRLASYLDKVRALE AN ELEVKIRDWYQ+Q P
Sbjct: 62  GGGYGGVLTASDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQGP 121

Query: 126 GPARDYSQYYRTIEELQNKILTATVDNANILLQIDNARLAADDFRTKFETEQALRLSVEA 185
           GP+RDYS YY TI++L++KIL AT++N+ I+LQIDNARLAADDFRTKFETEQALR+SVEA
Sbjct: 122 GPSRDYSHYYTTIQDLRDKILGATIENSRIVLQIDNARLAADDFRTKFETEQALRMSVEA 181

Query: 186 DINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGEINVEMDAAP 245
           DINGLRRVLDELTLAR DLEMQIE LKEELAYLKKNHEEE++ LRGQVGG+++VE+D+AP
Sbjct: 182 DINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEEEISTLRGQVGGQVSVEVDSAP 241

Query: 246 GVDLSRILNEMRDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQSGKSEISELRR 305
           G DL++IL++MR QYE MAE+NRKDAE WF S+TEELNREVA ++E +Q  +SE+++LRR
Sbjct: 242 GTDLAKILSDMRSQYEVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLRR 301

Query: 306 TMQALEIELQSQLSMKASLEGNLAETENRYCVQLSQIQGLIGSVEEQLAQLRCEMEQQNQ 365
           T+Q LEIELQSQLSMKA+LE  LAETE R+  QL+ IQ LI  +E QL  +R + E+QNQ
Sbjct: 302 TLQGLEIELQSQLSMKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQNQ 361

Query: 366 EYKILLDVKTRLEQEIATYRRLLEGEDAH 394
           EY+ L+D+K+RLEQEIATYR LLEG++ H
Sbjct: 362 EYQRLMDIKSRLEQEIATYRSLLEGQEDH 390


>gi|4557699 keratin 12 [Homo sapiens]
          Length = 494

 Score =  465 bits (1197), Expect = e-131
 Identities = 254/443 (57%), Positives = 319/443 (72%), Gaps = 35/443 (7%)

Query: 8   FTSSSSIKGSSGLGGGSSRTSCRLSGGLGAGSCRL---GSAGGLGSTLGGSSYSSCYSFG 64
           F+++S    SSG GGGS  +   ++GGLGAG  R    GS GGLG   GGS         
Sbjct: 57  FSAASMFGSSSGFGGGSGSS---MAGGLGAGYGRALGGGSFGGLGMGFGGSP-------- 105

Query: 65  SGGGYGSSFGGVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVKIRDWYQRQA 124
            GG  G   G   GLL+G EK TMQNLNDRLASYLDKVRALEEANTELE KIR+WY+ + 
Sbjct: 106 GGGSLGILSGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELENKIREWYETRG 165

Query: 125 PGPA----RDYSQYYRTIEELQNKILTATVDNANILLQIDNARLAADDFRTKFETEQALR 180
            G A     DYS+YY  IE+L+NKI++A++ NA +LLQIDNARLAA+DFR K+E E ALR
Sbjct: 166 TGTADASQSDYSKYYPLIEDLRNKIISASIGNAQLLLQIDNARLAAEDFRMKYENELALR 225

Query: 181 LSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGEINVE 240
             VEADINGLRRVLDELTL R DLEMQIE+L EELAY+KKNHE+E+ + R    GE++VE
Sbjct: 226 QGVEADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKNHEDELQSFRVGGPGEVSVE 285

Query: 241 MDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQSGKSEI 300
           MDAAPGVDL+R+LN+MR QYE +AE+NRKDAE WF  K+ EL +E++TN+E +QS KSE+
Sbjct: 286 MDAAPGVDLTRLLNDMRAQYETIAEQNRKDAEAWFIEKSGELRKEISTNTEQLQSSKSEV 345

Query: 301 SELRRTMQALEIELQSQLSMKASLEGNLAETENRYCVQLSQIQGLIGSVEEQLAQLRCEM 360
           ++LRR  Q LEIELQSQL+MK SLE +LAE E  YC QLSQ+Q LI ++E QL Q+R + 
Sbjct: 346 TDLRRAFQNLEIELQSQLAMKKSLEDSLAEAEGDYCAQLSQVQQLISNLEAQLLQVRADA 405

Query: 361 EQQNQEYKILLDVKTRLEQEIATYRRLLEGE-----------------DAHLTQYKKEPV 403
           E+QN +++ LL+VK RLE EI TYRRLL+GE                  A  T   K+P 
Sbjct: 406 ERQNVDHQRLLNVKARLELEIETYRRLLDGEAQGDGLEESLFVTDSKSQAQSTDSSKDPT 465

Query: 404 TTRQVRTIVEEVQDGKVISSREQ 426
            TR+++T+V+E+ +G+V+SS+ Q
Sbjct: 466 KTRKIKTVVQEMVNGEVVSSQVQ 488


>gi|195972866 keratin 10 [Homo sapiens]
          Length = 584

 Score =  463 bits (1192), Expect = e-130
 Identities = 254/388 (65%), Positives = 294/388 (75%), Gaps = 7/388 (1%)

Query: 10  SSSSIKGSSGLGGGSSRTSCRLS--GGLGAGSCRLGSAGGLGSTLGGSSYSSCYSFGS-G 66
           SS    G  G GGGS R S   S  GG   GS   GS GG GS  GGS     +  G  G
Sbjct: 70  SSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGG-GSFGGGSFGGGGFGGGGFG 128

Query: 67  GGYGSSFGGVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVKIRDWYQRQA-- 124
           GG+G  FGG  GLL+G EK TMQNLNDRLASYLDKVRALEE+N ELE KI++WY++    
Sbjct: 129 GGFGGGFGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELEGKIKEWYEKHGNS 188

Query: 125 -PGPARDYSQYYRTIEELQNKILTATVDNANILLQIDNARLAADDFRTKFETEQALRLSV 183
             G  RDYS+YY+TI++L+N+IL  T DNANILLQIDNARLAADDFR K+E E ALR SV
Sbjct: 189 HQGEPRDYSKYYKTIDDLKNQILNLTTDNANILLQIDNARLAADDFRLKYENEVALRQSV 248

Query: 184 EADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGEINVEMDA 243
           EADINGLRRVLDELTL +ADLEMQIE+L EELAYLKKNHEEEM  LR    G++NVEM+A
Sbjct: 249 EADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEEEMKDLRNVSTGDVNVEMNA 308

Query: 244 APGVDLSRILNEMRDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQSGKSEISEL 303
           APGVDL+++LN MR QYE++AE+NRKDAE WF  K++EL  E+  N E + S KSEI+EL
Sbjct: 309 APGVDLTQLLNNMRSQYEQLAEQNRKDAEAWFNEKSKELTTEIDNNIEQISSYKSEITEL 368

Query: 304 RRTMQALEIELQSQLSMKASLEGNLAETENRYCVQLSQIQGLIGSVEEQLAQLRCEMEQQ 363
           RR +QALEIELQSQL++K SLE +LAETE RYCVQLSQIQ  I ++EEQL Q+R E E Q
Sbjct: 369 RRNVQALEIELQSQLALKQSLEASLAETEGRYCVQLSQIQAQISALEEQLQQIRAETECQ 428

Query: 364 NQEYKILLDVKTRLEQEIATYRRLLEGE 391
           N EY+ LLD+K RLE EI TYR LLEGE
Sbjct: 429 NTEYQQLLDIKIRLENEIQTYRSLLEGE 456



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 32/79 (40%), Positives = 36/79 (45%), Gaps = 8/79 (10%)

Query: 13  SIKGSSGLGGGSSRTSCRLSGGLGAGSCRLGSAGGL------GSTLGGSSYSSCYSFGSG 66
           S+    G  GG  R      GG G GS   GS+GG       GS+ GG    S     SG
Sbjct: 451 SLLEGEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSG 510

Query: 67  GGY--GSSFGGVDGLLAGG 83
           GGY  GSS GG  G  +GG
Sbjct: 511 GGYGGGSSSGGHGGSSSGG 529



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 34/84 (40%), Positives = 39/84 (46%), Gaps = 8/84 (9%)

Query: 8   FTSSSSIKGSSGLGGGSSRTSCRLSGGLGAGSCRLGSAG---GLGSTLG--GSSYSSCYS 62
           +   SS  GSSG G G         GG G GS   GS+G   G GS+ G  G S S  Y 
Sbjct: 473 YGGGSSGGGSSGGGHGGGHGGSS-GGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYG 531

Query: 63  FGSGGGYGSSFGGVDGLLAGGEKA 86
            GS GG G  +GG  G   GG  +
Sbjct: 532 GGSSGGGGGGYGG--GSSGGGSSS 553



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 28/66 (42%), Positives = 30/66 (45%), Gaps = 3/66 (4%)

Query: 10  SSSSIKGSSGLGGGSSRTSCRLSGGLGAGSCRLGSAGGLGSTLGGSSYSSCYSFGSGGGY 69
           SS       G GGGSS       GG  +G    GS+GG G   GG S     S G G G 
Sbjct: 503 SSGGGSSGGGYGGGSSSGG---HGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGG 559

Query: 70  GSSFGG 75
           GSS GG
Sbjct: 560 GSSSGG 565



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 29/69 (42%), Positives = 31/69 (44%), Gaps = 6/69 (8%)

Query: 16  GSSGLG-GGSSRTSCRLSGGLGAGSCRLGSAGGLGSTLGGSSYSSCYSFGSGGGYGSSFG 74
           GSSG G GG S       GG G GS    S+GG G +  G  Y    S G GGGYG    
Sbjct: 493 GSSGGGYGGGSSGGGSSGGGYGGGS----SSGGHGGSSSG-GYGGGSSGGGGGGYGGGSS 547

Query: 75  GVDGLLAGG 83
           G      GG
Sbjct: 548 GGGSSSGGG 556



 Score = 37.7 bits (86), Expect = 0.020
 Identities = 31/64 (48%), Positives = 33/64 (51%), Gaps = 8/64 (12%)

Query: 17  SSGLGGGSSRTSCRLSGGLGAGSCRLGSAG-GLGSTLGGSSYSSCYSFG-SGGGYGSSFG 74
           SSG  GGSS      SGG G GS   G  G G GS+ GGSS    Y  G S GG+ SS  
Sbjct: 518 SSGGHGGSS------SGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSS 571

Query: 75  GVDG 78
           G  G
Sbjct: 572 GSVG 575



 Score = 34.3 bits (77), Expect = 0.23
 Identities = 25/63 (39%), Positives = 28/63 (44%), Gaps = 2/63 (3%)

Query: 10  SSSSIKGSSGLGGGSSRTSCRLSGGLGAGSCRLGSAGGLGSTLGGSSYSSCYSFGSGGGY 69
           SSS   G S  GG    +S    GG G GS   GS+ G G   GG S S  +   S G  
Sbjct: 517 SSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGG--YGGGSSSGGHKSSSSGSV 574

Query: 70  GSS 72
           G S
Sbjct: 575 GES 577



 Score = 31.2 bits (69), Expect = 1.9
 Identities = 20/48 (41%), Positives = 23/48 (47%), Gaps = 4/48 (8%)

Query: 8   FTSSSSIKGSSGLGGGSSRTSCRLSGGLGAGSCRLGSAGGLGSTLGGS 55
           +   SS  G  G GGGSS       GG G GS    S+GG  S+  GS
Sbjct: 530 YGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGS----SSGGHKSSSSGS 573


>gi|4504927 keratin 36 [Homo sapiens]
          Length = 467

 Score =  432 bits (1112), Expect = e-121
 Identities = 247/458 (53%), Positives = 308/458 (67%), Gaps = 46/458 (10%)

Query: 10  SSSSIKGSSGLGGGSSRTS-------CR---LSGGLGAGSCRLGSAGGLGSTLGGSSYSS 59
           S+ SIKG  G  GG SR S       CR   L+G  G  S       GLGS L GS  SS
Sbjct: 11  STGSIKGLCGTAGGISRVSSIRSVGSCRVPSLAGAAGYISSARSGLSGLGSCLPGSYLSS 70

Query: 60  -CYS---FGSGGGYGSSFGGVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVK 115
            C++    GSGG +       +G   G EK TMQ LNDRLA+YL+KVR LE  N ELE +
Sbjct: 71  ECHTSGFVGSGGWF------CEGSFNGSEKETMQFLNDRLANYLEKVRQLERENAELESR 124

Query: 116 IRDWYQRQAPGPARDYSQYYRTIEELQNKILTATVDNANILLQIDNARLAADDFRTKFET 175
           I++WY+ Q P    DY  Y++TIE+ Q KIL    +NA ++LQIDNA+LAADDFRTK+ET
Sbjct: 125 IQEWYEFQIPYICPDYQSYFKTIEDFQQKILLTKSENARLVLQIDNAKLAADDFRTKYET 184

Query: 176 EQALRLSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGG 235
           E +LR  VEADINGLRR+LDELTL +ADLE Q+E+LKEEL  LKKNHEEE++ LR Q+G 
Sbjct: 185 ELSLRQLVEADINGLRRILDELTLCKADLEAQVESLKEELMCLKKNHEEEVSVLRCQLGD 244

Query: 236 EINVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQS 295
            +NVE+DAAP VDL++IL +MR QYE + E NR+D E WF ++TEELN++V ++SE +Q 
Sbjct: 245 RLNVEVDAAPPVDLNKILEDMRCQYEALVENNRRDVEAWFNTQTEELNQQVVSSSEQLQC 304

Query: 296 GKSEISELRRTMQALEIELQSQLSMKASLEGNLAETENRYCVQLSQIQGLIGSVEEQLAQ 355
            ++EI ELRRT+ ALEIELQ+Q SM+ SLE  LAETE RY  QL+Q+Q LI +VE QL++
Sbjct: 305 CQTEIIELRRTVNALEIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLISNVEAQLSE 364

Query: 356 LRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGEDAHL-------------------- 395
           +RC++E+QNQEY++LLDVK RLE EIATYR LLEGED  L                    
Sbjct: 365 IRCDLERQNQEYQVLLDVKARLEGEIATYRHLLEGEDCKLPPQPCATACKPVIRVPSVPP 424

Query: 396 ------TQYKKEPVTTRQVRTIVEEVQDGKVISSREQV 427
                       P    Q+RTI EE++DGKVISSRE V
Sbjct: 425 VPCVPSVPCTPAPQVGTQIRTITEEIRDGKVISSREHV 462


>gi|192807292 keratin 24 [Homo sapiens]
          Length = 525

 Score =  428 bits (1101), Expect = e-120
 Identities = 244/469 (52%), Positives = 317/469 (67%), Gaps = 54/469 (11%)

Query: 9   TSSSSIKGSSGLGGGS---SRTSCRLSGGLGAGSCRLGSAGGLGSTLGGSSY-------- 57
           +S S   GSSG  GGS      SC + GG G G+   G+  G GS+ GG S         
Sbjct: 48  SSCSLSGGSSGAFGGSFGGGFGSCSVGGGFG-GASGSGTGFGGGSSFGGVSGFGRGSGFC 106

Query: 58  -SSCYSFGSGGGYGSSFGGVDG------LLAGGEKATMQNLNDRLASYLDKVRALEEANT 110
            SS +S G+ GG+ S  GG+ G      L +GGEK TMQNLNDRLA+YLDKVRALEEANT
Sbjct: 107 GSSRFSSGATGGFYSYGGGMGGGVGDGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANT 166

Query: 111 ELEVKIRDWYQRQAPGPA-----RDYSQYYRTIEELQNKILTATVDNANILLQIDNARLA 165
           +LE KI++WY +  PG       RDYS+YY  IE+L+N+I+ ATV+NA I+L IDNARLA
Sbjct: 167 DLENKIKEWYDKYGPGSGDGGSGRDYSKYYSIIEDLRNQIIAATVENAGIILHIDNARLA 226

Query: 166 ADDFRTKFETEQALRLSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEEE 225
           ADDFR K+E E  LR SVEADINGLR+VLD+LT+ R+DLEMQIE+  EELAYL+KNHEEE
Sbjct: 227 ADDFRLKYENELCLRQSVEADINGLRKVLDDLTMTRSDLEMQIESFTEELAYLRKNHEEE 286

Query: 226 MNALRGQVGGEINVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEDWFFSKTEELNRE 285
           M  ++G  GGE+ VEM+AAPG DL+++LN+MR QYE++AE+NR++AE+ F  ++  L  +
Sbjct: 287 MKNMQGSSGGEVTVEMNAAPGTDLTKLLNDMRAQYEELAEQNRREAEERFNKQSASLQAQ 346

Query: 286 VATNSELVQSGKSEISELRRTMQALEIELQSQLSMKASLEGNLAETENRYCVQLSQIQGL 345
           ++T++    S K+EI+EL+RT+QALEIELQSQL+MK+SLEG LA+TE  Y  QLS+IQ  
Sbjct: 347 ISTDAGAATSAKNEITELKRTLQALEIELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQ 406

Query: 346 IGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGE-------------- 391
           I ++EE++ Q+  E + QN EYK LLD+KTRLE EI TYRRLL+GE              
Sbjct: 407 ISALEEEICQIWGETKCQNAEYKQLLDIKTRLEVEIETYRRLLDGEGGGSSFAEFGGRNS 466

Query: 392 ----------------DAHLTQYKKEPVTTRQVRTIVEEVQDGKVISSR 424
                               +   ++   TR  +TIVEE+ DGKV+SS+
Sbjct: 467 GSVNMGSRDLVSGDSRSGSCSGQGRDSSKTRVTKTIVEELVDGKVVSSQ 515


>gi|153945736 keratin 27 [Homo sapiens]
          Length = 459

 Score =  421 bits (1082), Expect = e-118
 Identities = 238/439 (54%), Positives = 303/439 (69%), Gaps = 25/439 (5%)

Query: 7   QFTSSSSIKGSSGLGGGSSRTSCRLSGGLGAGSCRLGSAGGLGS----TLGGSSYSSCYS 62
           +F+S+S   GS G G GS R S   SGG G G+       G+GS      GGSS +  Y 
Sbjct: 4   RFSSTSRRLGSCG-GTGSVRLS---SGGAGFGAGNTCGVPGIGSGFSCAFGGSSSAGGYG 59

Query: 63  FGSGGGYGSSF---GGVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVKIRDW 119
            G GGG  S     G   GLL+G EK TMQNLNDRLASYL+ VRALEEAN +LE KI+ W
Sbjct: 60  GGLGGGSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRALEEANADLEQKIKGW 119

Query: 120 YQRQAPGPAR----DYSQYYRTIEELQNKILTATVDNANILLQIDNARLAADDFRTKFET 175
           Y++  PG  R    DYS+Y+  I+EL+N+I++AT  NA+++LQ DNARL ADDFR KFE 
Sbjct: 120 YEKFGPGSCRGLDHDYSRYFPIIDELKNQIISATTSNAHVVLQNDNARLTADDFRLKFEN 179

Query: 176 EQALRLSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGG 235
           E AL  SVEADINGLRRVLDELTL R DLE+Q+E L EELAYLKKNHEEEM AL+   GG
Sbjct: 180 ELALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEELAYLKKNHEEEMKALQCAAGG 239

Query: 236 EINVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQS 295
            +NVEM+AAPGVDL+ +LN MR +YE +AE+NR+DAE WF  K+  L ++++ ++    S
Sbjct: 240 NVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISDDAGATTS 299

Query: 296 GKSEISELRRTMQALEIELQSQLSMKASLEGNLAETENRYCVQLSQIQGLIGSVEEQLAQ 355
            ++E+ E++RT+Q LEIELQS L+ K SLE +L ETE+ YC QL+QIQ  IG++EEQL Q
Sbjct: 300 ARNELIEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQ 359

Query: 356 LRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGEDAHLTQYK---------KEPVTTR 406
           +R E E Q  EY+ LLD+K  LE+EI TY  L++GED   ++ K         K+   T 
Sbjct: 360 VRTETEGQKLEYEQLLDIKVHLEKEIETYCLLIDGEDGSCSKSKGYGGPGNQTKDSSKTT 419

Query: 407 QVRTIVEEVQD-GKVISSR 424
            V+T+VEE+   GKV+SSR
Sbjct: 420 IVKTVVEEIDPRGKVLSSR 438


>gi|114431246 keratin 25D [Homo sapiens]
          Length = 464

 Score =  414 bits (1065), Expect = e-116
 Identities = 230/439 (52%), Positives = 296/439 (67%), Gaps = 34/439 (7%)

Query: 4   SIRQFTSSSSIKGSSGLGG--GSSRTSCRLSGGLGAGSCRLGSAGGLGSTLGGSSYSSCY 61
           S+R     +   GSS  GG    S  SC L GGLG+      + G LG+       ++C 
Sbjct: 20  SVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGN-------AACI 72

Query: 62  SFGSGGGYGSSFGGVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVKIRDWYQ 121
            F    G         GLL+G EK TMQNLNDRLASYLD VRALEEAN ELE KI+ WY+
Sbjct: 73  GFAGSEG---------GLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYE 123

Query: 122 RQAPGPAR----DYSQYYRTIEELQNKILTATVDNANILLQIDNARLAADDFRTKFETEQ 177
           +  PG  R    DYS+Y+ TIE+L+NKI+++T  NAN++LQIDNARLAADDFR K+E E 
Sbjct: 124 KYGPGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENEL 183

Query: 178 ALRLSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGEI 237
            L  +VEADINGLRRVLDELTL R D E+Q E+L EE+ YLKKNHEEEM AL+   GG +
Sbjct: 184 TLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNV 243

Query: 238 NVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQSGK 297
           NVEM+AAPGVDL+ +LN MR +YE +AE+NRKDAE WF  K+  L ++++ +S      +
Sbjct: 244 NVEMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFAR 303

Query: 298 SEISELRRTMQALEIELQSQLSMKASLEGNLAETENRYCVQLSQIQGLIGSVEEQLAQLR 357
           S+++E+RRT+Q LEI+LQS ++ K SLE +L ETE+ YC QL+QIQ  IG++EEQL Q+R
Sbjct: 304 SQLTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVR 363

Query: 358 CEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGEDAHLTQYK-----------KEPVTTR 406
            E E Q  EY+ LLDVK  LE+EI TY RL++G+    ++ K           K+   T 
Sbjct: 364 TETEGQKLEYEHLLDVKVHLEKEIETYCRLIDGDGNSCSKSKGFGSGSPGNSSKDLSKTT 423

Query: 407 QVRTIVEEV-QDGKVISSR 424
            V+T+VEE+ Q GKV+SSR
Sbjct: 424 LVKTVVEELDQRGKVLSSR 442


>gi|94538345 keratin 35 [Homo sapiens]
          Length = 455

 Score =  407 bits (1047), Expect = e-114
 Identities = 218/402 (54%), Positives = 291/402 (72%), Gaps = 20/402 (4%)

Query: 10  SSSSIKGSSGLGGGSSRTSCRLSGGLGAGSCRLGSAGGLGST-------LGGSSYSSCYS 62
           SS S+K   G  GGS+R S   S    + SC+L S   +  +       LG SSY +   
Sbjct: 11  SSGSLKSPGGASGGSTRVSAMYS----SSSCKLPSLSPVARSFSACSVGLGRSSYRATSC 66

Query: 63  FGS----GGGYGSSFGGV-----DGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELE 113
             +     GG+ +S+ G      +G+L G EK TMQ+LNDRLA YL+KVR LE+ N  LE
Sbjct: 67  LPALCLPAGGFATSYSGGGGWFGEGILTGNEKETMQSLNDRLAGYLEKVRQLEQENASLE 126

Query: 114 VKIRDWYQRQAPGPARDYSQYYRTIEELQNKILTATVDNANILLQIDNARLAADDFRTKF 173
            +IR+W ++Q P    DY  Y+RTIEELQ K L +  +NA ++++IDNA+LAADDFRTK+
Sbjct: 127 SRIREWCEQQVPYMCPDYQSYFRTIEELQKKTLCSKAENARLVVEIDNAKLAADDFRTKY 186

Query: 174 ETEQALRLSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQV 233
           ETE +LR  VE+DINGLRR+LD+LTL ++DLE Q+E+LKEEL  LKKNHEEE+N+LR Q+
Sbjct: 187 ETEVSLRQLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKKNHEEEVNSLRCQL 246

Query: 234 GGEINVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELV 293
           G  +NVE+DAAP VDL+R+L EMR QYE + E NR+DAEDW  +++EELN++V ++SE +
Sbjct: 247 GDRLNVEVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSEELNQQVVSSSEQL 306

Query: 294 QSGKSEISELRRTMQALEIELQSQLSMKASLEGNLAETENRYCVQLSQIQGLIGSVEEQL 353
           QS ++EI ELRRT+ ALEIELQ+Q SM+ +LE  LAETE RY  QL+Q+Q +I +VE QL
Sbjct: 307 QSCQAEIIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQLAQMQCMITNVEAQL 366

Query: 354 AQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGEDAHL 395
           A++R ++E+QNQEY++LLDV+ RLE EI TYR LLE ED+ L
Sbjct: 367 AEIRADLERQNQEYQVLLDVRARLECEINTYRGLLESEDSKL 408


>gi|27894337 keratin 20 [Homo sapiens]
          Length = 424

 Score =  398 bits (1023), Expect = e-111
 Identities = 208/395 (52%), Positives = 281/395 (71%), Gaps = 14/395 (3%)

Query: 35  LGAGSCRLGSAGGLGSTLGGSSYSSCYSFGSGGGYGSSFGGVDGLLAGGEKATMQNLNDR 94
           LG      G AGG G  +  S ++          YGS   G   L  G EK  MQNLNDR
Sbjct: 29  LGTTPSVYGGAGGRGIRISNSRHTV--------NYGSDLTGGGDLFVGNEKMAMQNLNDR 80

Query: 95  LASYLDKVRALEEANTELEVKIRDWYQRQAPGPARDYSQYYRTIEELQNKILTATVDNAN 154
           LASYL+KVR LE++N++LEV+I+ WY+  AP   RDYS YYR IEEL+++I  A + NA 
Sbjct: 81  LASYLEKVRTLEQSNSKLEVQIKQWYETNAPRAGRDYSAYYRQIEELRSQIKDAQLQNAR 140

Query: 155 ILLQIDNARLAADDFRTKFETEQALRLSVEADINGLRRVLDELTLARADLEMQIENLKEE 214
            +LQIDNA+LAA+DFR K+ETE+ +RL+VEAD+ GL +V D+LTL + DLE+QIE L ++
Sbjct: 141 CVLQIDNAKLAAEDFRLKYETERGIRLTVEADLQGLNKVFDDLTLHKTDLEIQIEELNKD 200

Query: 215 LAYLKKNHEEEMNALRGQVGGEINVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEDW 274
           LA LKK H+EE++ L   +G  +NVE+DAAPG++L  I+NEMR +YE MA+KN ++A++ 
Sbjct: 201 LALLKKEHQEEVDGLHKHLGNTVNVEVDAAPGLNLGVIMNEMRQKYEVMAQKNLQEAKEQ 260

Query: 275 FFSKTEELNREVATNSELVQSGKSEISELRRTMQALEIELQSQLSMKASLEGNLAETENR 334
           F  +T  L ++V  N+E ++  + +++ELRRT Q+LEIELQS LSMK SLE  L ET+ R
Sbjct: 261 FERQTAVLQQQVTVNTEELKGTEVQLTELRRTSQSLEIELQSHLSMKESLEHTLEETKAR 320

Query: 335 YCVQLSQIQGLIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGEDAH 394
           Y  QL+ +Q L+ S+E QL Q+R  ME+QN EY ILLD+KTRLEQEIATYRRLLEGED  
Sbjct: 321 YSSQLANLQSLLSSLEAQLMQIRSNMERQNNEYHILLDIKTRLEQEIATYRRLLEGEDVK 380

Query: 395 LTQY------KKEPVTTRQVRTIVEEVQDGKVISS 423
            T+Y      +++   TR+++T+V+EV DGKV+SS
Sbjct: 381 TTEYQLSTLEERDIKKTRKIKTVVQEVVDGKVVSS 415


>gi|31559829 keratin 25 [Homo sapiens]
          Length = 450

 Score =  385 bits (988), Expect = e-107
 Identities = 215/439 (48%), Positives = 285/439 (64%), Gaps = 43/439 (9%)

Query: 28  SCRLSGGLGAGSCRLGSAGGLGSTLGGSSY---SSCYSFGSGGGYGSSFGGVD------- 77
           S RLS      SC   + G L    GG+S+   +SC   G G G+ S+FGG         
Sbjct: 2   SLRLSSA-SRRSCPRPTTGSLRLYGGGTSFGTGNSCGISGIGSGFSSAFGGSSSGGNTGG 60

Query: 78  ------------GLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVKIRDWYQRQAP 125
                       GLL+G EK TMQNLNDRLASYLD V ALEEAN +LE KI+ WY++  P
Sbjct: 61  GNPCAGFTVNERGLLSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGWYEKFGP 120

Query: 126 GPAR----DYSQYYRTIEELQNKILTATVDNANILLQIDNARLAADDFRTKFETEQALRL 181
           G  R    DYS+Y+  I++L+N+I+ +T  NAN +LQIDNARL ADDFR K+E E AL  
Sbjct: 121 GSCRGLDHDYSRYFPIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENELALHQ 180

Query: 182 SVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGEINVEM 241
           SVEAD+NGLRRVLDE+TL R DLE+Q E L EE+ YLKKNH+EEM  L+   GG +NVEM
Sbjct: 181 SVEADVNGLRRVLDEITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAAGGNVNVEM 240

Query: 242 DAAPGVDLSRILNEMRDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQSGKSEIS 301
           +AAPGVDL+ +LN MR +YE +AE+NR+DAE WF  K+  L ++++ +     S ++E++
Sbjct: 241 NAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATTSARNELT 300

Query: 302 ELRRTMQALEIELQSQLSMKASLEGNLAETENRYCVQLSQIQGLIGSVEEQLAQLRCEME 361
           E++RT+Q LEIELQS L+ K SLE +L ETE+ YC QL+QIQ  IG++EEQL Q+R E E
Sbjct: 301 EMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETE 360

Query: 362 QQNQEYKILLDVKTRLEQEIATYRRLLEGED---------------AHLTQYKKEPVTTR 406
            Q  EY+ LLD+K  LE+EI TY  L+ G+D                ++    K+P    
Sbjct: 361 GQKLEYEQLLDIKLHLEKEIETYCLLIGGDDGACKSGGYKSKDYGSGNVGSQVKDPAKAI 420

Query: 407 QVRTIVEEV-QDGKVISSR 424
            V+ ++EEV Q  K++++R
Sbjct: 421 VVKKVLEEVDQRSKILTTR 439


>gi|55956899 keratin 9 [Homo sapiens]
          Length = 623

 Score =  375 bits (963), Expect = e-104
 Identities = 214/431 (49%), Positives = 277/431 (64%), Gaps = 43/431 (9%)

Query: 3   TSIRQFTSSSSIKG------SSGLGGGSSRTSCRLSGG-----LGAGSCRLGSAGGLGST 51
           +S  +F+SS    G      SSG GGGSSR   R  GG      G GS    SA  LG  
Sbjct: 30  SSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYGGGSGGGFSASSLGGG 89

Query: 52  LGGSS----------YSSCYSFGSG----------GGYGSSFGGVDG-----------LL 80
            GG S          YSS   FG G          GGYGS FGG  G           +L
Sbjct: 90  FGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGFGGGYGSGFGGFGGFGGGAGGGDGGIL 149

Query: 81  AGGEKATMQNLNDRLASYLDKVRALEEANTELEVKIRDWYQRQAPGPA-RDYSQYYRTIE 139
              EK+TMQ LN RLASYLDKV+ALEEAN +LE KI+DWY ++ P    ++YS YY TI+
Sbjct: 150 TANEKSTMQELNSRLASYLDKVQALEEANNDLENKIQDWYDKKGPAAIQKNYSPYYNTID 209

Query: 140 ELQNKILTATVDNANILLQIDNARLAADDFRTKFETEQALRLSVEADINGLRRVLDELTL 199
           +L+++I+  TV N   LL IDN R+  DDFR KFE EQ LR  V+ADINGLR+VLD LT+
Sbjct: 210 DLKDQIVDLTVGNNKTLLDIDNTRMTLDDFRIKFEMEQNLRQGVDADINGLRQVLDNLTM 269

Query: 200 ARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGEINVEMDAAPGVDLSRILNEMRDQ 259
            ++DLEMQ E L+EEL  LKKNH+EEM+ L GQ  G++NVE++ APG DL++ LN+MR +
Sbjct: 270 EKSDLEMQYETLQEELMALKKNHKEEMSQLTGQNSGDVNVEINVAPGKDLTKTLNDMRQE 329

Query: 260 YEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQSGKSEISELRRTMQALEIELQSQLS 319
           YE++  KNRKD E+ + ++  ++  EV+++ + VQS   E+++LR  +Q LEIELQSQLS
Sbjct: 330 YEQLIAKNRKDIENQYETQITQIEHEVSSSGQEVQSSAKEVTQLRHGVQELEIELQSQLS 389

Query: 320 MKASLEGNLAETENRYCVQLSQIQGLIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQ 379
            KA+LE +L +T+NRYC QL  IQ  I ++E Q+  +R E+E QNQEY +LL +K RLE+
Sbjct: 390 KKAALEKSLEDTKNRYCGQLQMIQEQISNLEAQITDVRQEIECQNQEYSLLLSIKMRLEK 449

Query: 380 EIATYRRLLEG 390
           EI TY  LLEG
Sbjct: 450 EIETYHNLLEG 460



 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 30/73 (41%), Positives = 33/73 (45%), Gaps = 7/73 (9%)

Query: 10  SSSSIKGSSGLGGGSSRTSCRLSGGLGAGSCRLGSAGGLGSTLGGSSYSSCYSFGSGGGY 69
           S  S  G SG GGGS       SGG  +G    G +GG G   GG S       GSGGG 
Sbjct: 516 SGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGS-------GSGGGS 568

Query: 70  GSSFGGVDGLLAG 82
           G  +GG  G   G
Sbjct: 569 GGGYGGGSGSRGG 581



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 35/72 (48%), Positives = 37/72 (51%), Gaps = 8/72 (11%)

Query: 17  SSGLGGGSSRTSCRLSGGLGAGSCRLGSAGGLGSTLGGSSYSSCYSFGSGGGYGSSFGGV 76
           S G GGG S  S    G  G GS   GS GG G   GG S S   S GS GG GS FGG 
Sbjct: 543 SGGSGGGHSGGS---GGNYGGGS---GSGGGSGGGYGGGSGSRGGSGGSHGG-GSGFGGE 595

Query: 77  D-GLLAGGEKAT 87
             G   GGE+A+
Sbjct: 596 SGGSYGGGEEAS 607



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 31/69 (44%), Positives = 34/69 (49%), Gaps = 7/69 (10%)

Query: 15  KGSSGLGGGSSRTSCRLSGGLGAGSCRLGSAGGLGSTLGGSSYSSCYSFGSGGGYGSSFG 74
           +GS G G G S       GG G GS   GS GG G + GG S S     GSGGGYG   G
Sbjct: 487 RGSRG-GSGGSYGGGGSGGGYGGGS---GSRGGSGGSYGGGSGS---GGGSGGGYGGGSG 539

Query: 75  GVDGLLAGG 83
           G     +GG
Sbjct: 540 GGHSGGSGG 548



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 28/72 (38%), Positives = 31/72 (43%), Gaps = 14/72 (19%)

Query: 10  SSSSIKGSSGLGGGSSRTSCRLSGGLGAGSCRLGSAG-------GLGSTLGGSSYSSCYS 62
           S  +  G SG GGGS        GG G GS   G +G       G G   GGS      +
Sbjct: 554 SGGNYGGGSGSGGGSG-------GGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEA 606

Query: 63  FGSGGGYGSSFG 74
            GSGGGYG   G
Sbjct: 607 SGSGGGYGGGSG 618



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 26/60 (43%), Positives = 29/60 (48%), Gaps = 4/60 (6%)

Query: 16  GSSGLGGGSSRTSCRLSGGLGAGSCRLGSAGGLGSTLGGSSYSSCYSFGSGGGYGSSFGG 75
           GS G  GG S +     G  G GS   GS GG G   GG S    +S GSGGG+    GG
Sbjct: 501 GSGGGYGGGSGSRGGSGGSYGGGS---GSGGGSGGGYGGGS-GGGHSGGSGGGHSGGSGG 556



 Score = 38.9 bits (89), Expect = 0.009
 Identities = 28/66 (42%), Positives = 30/66 (45%), Gaps = 6/66 (9%)

Query: 16  GSSGLGGGSSRTSCRLSGGLGAGSCRLGSAGGLG---STLGGSSYSSCYSFGSGGGYGSS 72
           G  G GG   R S   SGG   G    GS GG G    + GGS  S     GSGGG G  
Sbjct: 477 GRGGSGGSYGRGSRGGSGGSYGGG---GSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGG 533

Query: 73  FGGVDG 78
           +GG  G
Sbjct: 534 YGGGSG 539



 Score = 36.2 bits (82), Expect = 0.059
 Identities = 32/74 (43%), Positives = 33/74 (44%), Gaps = 5/74 (6%)

Query: 12  SSIKGSSGLGG--GSSRTSCRLSGGLGAGSCRLGSAGGLGSTLGGSSYSSCYSFGSGGGY 69
           SS  G  GLGG  GS  +  R S G   GS      GG G   GG S S   S GS GG 
Sbjct: 467 SSGAGKIGLGGRGGSGGSYGRGSRGGSGGSY---GGGGSGGGYGGGSGSRGGSGGSYGGG 523

Query: 70  GSSFGGVDGLLAGG 83
             S GG  G   GG
Sbjct: 524 SGSGGGSGGGYGGG 537



 Score = 32.7 bits (73), Expect = 0.66
 Identities = 20/48 (41%), Positives = 21/48 (43%)

Query: 11  SSSIKGSSGLGGGSSRTSCRLSGGLGAGSCRLGSAGGLGSTLGGSSYS 58
           S S  GS G  GG S       G  G G    GS GG G   G SS+S
Sbjct: 576 SGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGSGKSSHS 623



 Score = 29.6 bits (65), Expect = 5.6
 Identities = 22/48 (45%), Positives = 24/48 (50%), Gaps = 10/48 (20%)

Query: 43 GSAGGLGSTLGG---SSYSSCYSFGSGGGYG-----SSFGGVDGLLAG 82
          G  GGLGS  GG   SSYS   S G GGG G     S +GG    + G
Sbjct: 17 GGGGGLGS--GGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCG 62


>gi|14917117 keratin 33A [Homo sapiens]
          Length = 404

 Score =  373 bits (958), Expect = e-103
 Identities = 209/384 (54%), Positives = 269/384 (70%), Gaps = 25/384 (6%)

Query: 17  SSGLGGGSSRTSCRLSGGLGAGSCRLGSAGGLGSTLGGS-----SYSSCYSFGSGGGYGS 71
           S GL   S RTSC  S      SC        G TL G+     + S+C  F        
Sbjct: 4   SCGLPSLSCRTSCS-SRPCVPPSCH-------GCTLPGACNIPANVSNCNWF-------- 47

Query: 72  SFGGVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVKIRDWYQRQAPGPARDY 131
                +G   G EK TMQ LNDRLASYL+KVR LE  N ELE  IR+  Q+Q P     Y
Sbjct: 48  ----CEGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVCASY 103

Query: 132 SQYYRTIEELQNKILTATVDNANILLQIDNARLAADDFRTKFETEQALRLSVEADINGLR 191
             Y++TIEELQ KIL +  +NA +++QIDNA+LA+DDFRTK+ETE +LR  VE+DINGLR
Sbjct: 104 QSYFKTIEELQQKILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLR 163

Query: 192 RVLDELTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGEINVEMDAAPGVDLSR 251
           R+LDELTL R+DLE Q+E+LKEEL  LK+NHE+E+N LR Q+G  +NVE+DAAP VDL++
Sbjct: 164 RILDELTLCRSDLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQ 223

Query: 252 ILNEMRDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQSGKSEISELRRTMQALE 311
           +LNE R QYE + E NR++ E WF ++TEELN++V ++SE +QS ++EI ELRRT+ ALE
Sbjct: 224 VLNETRSQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALE 283

Query: 312 IELQSQLSMKASLEGNLAETENRYCVQLSQIQGLIGSVEEQLAQLRCEMEQQNQEYKILL 371
           IELQ+Q +++ SLE  L E+E RY  QLSQ+Q LI +VE QLA++R ++E+QNQEY++LL
Sbjct: 284 IELQAQHNLRDSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLL 343

Query: 372 DVKTRLEQEIATYRRLLEGEDAHL 395
           DV+ RLE EI TYR LLE ED  L
Sbjct: 344 DVRARLECEINTYRSLLESEDCKL 367


>gi|10337581 type I hair keratin 3B [Homo sapiens]
          Length = 404

 Score =  373 bits (958), Expect = e-103
 Identities = 191/319 (59%), Positives = 249/319 (78%)

Query: 77  DGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVKIRDWYQRQAPGPARDYSQYYR 136
           +G   G EK TMQ LNDRLASYL+KVR LE  N ELE  IR+  Q+Q P     Y  Y++
Sbjct: 49  EGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFK 108

Query: 137 TIEELQNKILTATVDNANILLQIDNARLAADDFRTKFETEQALRLSVEADINGLRRVLDE 196
           TIEELQ KIL +  +NA +++QIDNA+LAADDFRTK++TEQ+LR  VE+DIN LRR+LDE
Sbjct: 109 TIEELQQKILCSKSENARLVVQIDNAKLAADDFRTKYQTEQSLRQLVESDINSLRRILDE 168

Query: 197 LTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGEINVEMDAAPGVDLSRILNEM 256
           LTL R+DLE Q+E+LKEEL  LK+NHE+E+N LR Q+G  +NVE+DAAP VDL+++LNE 
Sbjct: 169 LTLCRSDLEAQMESLKEELLSLKQNHEQEVNTLRCQLGDRLNVEVDAAPAVDLNQVLNET 228

Query: 257 RDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQSGKSEISELRRTMQALEIELQS 316
           R+QYE + E NR++ E WF ++TEELN++V ++SE +QS ++EI ELRRT+ ALEIELQ+
Sbjct: 229 RNQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQA 288

Query: 317 QLSMKASLEGNLAETENRYCVQLSQIQGLIGSVEEQLAQLRCEMEQQNQEYKILLDVKTR 376
           Q +++ SLE  L E+E RY  QLSQ+Q LI +VE QLA++R ++E+QNQEY++LLDV+ R
Sbjct: 289 QHNLRYSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRAR 348

Query: 377 LEQEIATYRRLLEGEDAHL 395
           LE EI TYR LLE ED  L
Sbjct: 349 LECEINTYRSLLESEDCKL 367


>gi|14917115 keratin 31 [Homo sapiens]
          Length = 416

 Score =  373 bits (957), Expect = e-103
 Identities = 191/319 (59%), Positives = 247/319 (77%)

Query: 77  DGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVKIRDWYQRQAPGPARDYSQYYR 136
           +G   G EK TMQ LNDRLASYL+KVR LE  N ELE  IR+  Q+Q P     Y  Y++
Sbjct: 49  EGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFK 108

Query: 137 TIEELQNKILTATVDNANILLQIDNARLAADDFRTKFETEQALRLSVEADINGLRRVLDE 196
           TIEELQ KIL    +NA +++QIDNA+LAADDFRTK++TE +LR  VE+DINGLRR+LDE
Sbjct: 109 TIEELQQKILCTKSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRILDE 168

Query: 197 LTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGEINVEMDAAPGVDLSRILNEM 256
           LTL ++DLE Q+E+LKEEL  LK NHE+E+N LR Q+G  +NVE+DAAP VDL+R+LNE 
Sbjct: 169 LTLCKSDLEAQVESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVLNET 228

Query: 257 RDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQSGKSEISELRRTMQALEIELQS 316
           R QYE + E NR++ E WF ++TEELN++V ++SE +QS ++EI ELRRT+ ALEIELQ+
Sbjct: 229 RSQYEALVETNRREVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQA 288

Query: 317 QLSMKASLEGNLAETENRYCVQLSQIQGLIGSVEEQLAQLRCEMEQQNQEYKILLDVKTR 376
           Q +++ SLE  L E+E RY  QLSQ+Q LI +VE QLA++R ++E+QNQEY++LLDV+ R
Sbjct: 289 QHNLRDSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRAR 348

Query: 377 LEQEIATYRRLLEGEDAHL 395
           LE EI TYR LLE ED +L
Sbjct: 349 LECEINTYRSLLESEDCNL 367


>gi|14917119 keratin 34 [Homo sapiens]
          Length = 436

 Score =  372 bits (954), Expect = e-103
 Identities = 187/319 (58%), Positives = 247/319 (77%)

Query: 77  DGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVKIRDWYQRQAPGPARDYSQYYR 136
           +G   G EK TMQ LNDRLASYL+KVR LE  N ELE  I++  Q+Q P     Y  Y++
Sbjct: 91  EGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELEKLIQERSQQQEPLLCPSYQSYFK 150

Query: 137 TIEELQNKILTATVDNANILLQIDNARLAADDFRTKFETEQALRLSVEADINGLRRVLDE 196
           TIEELQ KIL A  +NA +++ IDNA+LA+DDFR+K++TEQ+LRL VE+DIN +RR+LDE
Sbjct: 151 TIEELQQKILCAKAENARLVVNIDNAKLASDDFRSKYQTEQSLRLLVESDINSIRRILDE 210

Query: 197 LTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGEINVEMDAAPGVDLSRILNEM 256
           LTL ++DLE Q+E+L+EEL  LKKNHEEE+N LR Q+G  +NVE+D AP VDL+++LNE 
Sbjct: 211 LTLCKSDLESQVESLREELICLKKNHEEEVNTLRSQLGDRLNVEVDTAPTVDLNQVLNET 270

Query: 257 RDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQSGKSEISELRRTMQALEIELQS 316
           R QYE + E NR++ E WF ++TEELN++V ++SE +QS ++EI ELRRT+ ALEIELQ+
Sbjct: 271 RSQYEALVEINRREVEQWFATQTEELNKQVVSSSEQLQSCQAEIIELRRTVNALEIELQA 330

Query: 317 QLSMKASLEGNLAETENRYCVQLSQIQGLIGSVEEQLAQLRCEMEQQNQEYKILLDVKTR 376
           Q +++ SLE  L E+E  Y  QLSQ+Q LI +VE QLA++RC++E+QNQEY++LLDV+ R
Sbjct: 331 QHNLRDSLENTLTESEAHYSSQLSQVQSLITNVESQLAEIRCDLERQNQEYQVLLDVRAR 390

Query: 377 LEQEIATYRRLLEGEDAHL 395
           LE EI TYR LLE ED  L
Sbjct: 391 LECEINTYRSLLESEDCKL 409


>gi|116488398 keratin 32 [Homo sapiens]
          Length = 448

 Score =  365 bits (936), Expect = e-101
 Identities = 192/339 (56%), Positives = 249/339 (73%), Gaps = 1/339 (0%)

Query: 58  SSCYSF-GSGGGYGSSFGGVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVKI 116
           SSC +  G  G  G      +G   G EK TMQ LNDRLASYL +VR LE+ N ELE +I
Sbjct: 69  SSCQAASGISGSMGPGSWYSEGAFNGNEKETMQFLNDRLASYLTRVRQLEQENAELESRI 128

Query: 117 RDWYQRQAPGPARDYSQYYRTIEELQNKILTATVDNANILLQIDNARLAADDFRTKFETE 176
           ++    Q      DY  ++RTIEELQ KIL    +NA +++ IDNA+LAADDFR K+E E
Sbjct: 129 QEASHSQVLTMTPDYQSHFRTIEELQQKILCTKAENARMVVNIDNAKLAADDFRAKYEAE 188

Query: 177 QALRLSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGE 236
            A+R  VEADINGLRR+LD+LTL +ADLE Q+E+LKEEL  LKKNHEEE+ +LR Q+G  
Sbjct: 189 LAMRQLVEADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKNHEEEVGSLRCQLGDR 248

Query: 237 INVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQSG 296
           +N+E+DAAP VDL+R+L EMR QYE M E NR+D E+WF  + EELN++VAT+SE +Q+ 
Sbjct: 249 LNIEVDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEELNQQVATSSEQLQNY 308

Query: 297 KSEISELRRTMQALEIELQSQLSMKASLEGNLAETENRYCVQLSQIQGLIGSVEEQLAQL 356
           +S+I +LRRT+  LEIELQ+Q S++ SLE  L E+E RY  QL+Q+Q +I +VE QLA++
Sbjct: 309 QSDIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQMQCMITNVEAQLAEI 368

Query: 357 RCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGEDAHL 395
           R ++E+QNQEY++LLDV+ RLE EI TYR LLE ED  L
Sbjct: 369 RADLERQNQEYQVLLDVRARLEGEINTYRSLLENEDCKL 407


>gi|31559815 keratin 26 [Homo sapiens]
          Length = 468

 Score =  365 bits (936), Expect = e-101
 Identities = 221/440 (50%), Positives = 282/440 (64%), Gaps = 36/440 (8%)

Query: 20  LGGGSSRT-----SCRLSGG---LGAGSCRLGSAG--GLGSTLGGSSYSSCYSFGSGGGY 69
           L GGS R      S RLSGG     AG+  +GS        TL G S    +   SGGG 
Sbjct: 5   LSGGSRRICSRTGSGRLSGGGTGFVAGNVCVGSGARSSFSCTLEGISSGGSFC-NSGGGL 63

Query: 70  GSS-----FGGVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVKIRDWYQRQA 124
           GS       G    LL+G EK TMQNLNDRLASYLD V ALEEAN +LE KI+  Y++  
Sbjct: 64  GSGACAGFLGNEHSLLSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIKGRYEKCE 123

Query: 125 PGPAR----DYSQYYRTIEELQNKILTATVDNANILLQIDNARLAADDFRTKFETEQALR 180
           PG +R    DYS+Y+  IE+L+ +I +AT+ NA+I+LQ DNARL ADDFR K+E E AL 
Sbjct: 124 PGSSREHDHDYSRYFSVIEDLKRQITSATICNASIVLQNDNARLTADDFRLKYENELALH 183

Query: 181 LSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGEINVE 240
            SVEAD +GLRRVLDELTL   DLE+Q E L EEL YLKK+HEEEM  L+   GG +NVE
Sbjct: 184 HSVEADTSGLRRVLDELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTAGGNVNVE 243

Query: 241 MDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQSGKSEI 300
           M+A PGVDL+ +LN MR +YE +AE+NRKDAE WF  ++  L ++++ +     + ++E+
Sbjct: 244 MNATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAATAARNEL 303

Query: 301 SELRRTMQALEIELQSQLSMKASLEGNLAETENRYCVQLSQIQGLIGSVEEQLAQLRCEM 360
           +EL+R +Q LEIELQS +++K S E +LAETE  YC QL QIQ  IG +EEQL Q+R E 
Sbjct: 304 TELKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQQIRTET 363

Query: 361 EQQNQEYKILLDVKTRLEQEIATYRRLLEGED--AHLTQYK-------------KEPVTT 405
           E Q  EY+ LLDVK  LE+EI  Y  LL+GE+  +  T YK             K+    
Sbjct: 364 EGQKLEYEQLLDVKIFLEKEIDIYCNLLDGEERKSKSTCYKSKGYRPVNSGNQAKDSTEE 423

Query: 406 RQVRTIVEEV-QDGKVISSR 424
             V+T+VEE+ Q G ++S R
Sbjct: 424 TIVKTVVEELDQIGNLLSLR 443


>gi|125490370 type I hair keratin KA36 [Homo sapiens]
          Length = 431

 Score =  338 bits (866), Expect = 7e-93
 Identities = 185/390 (47%), Positives = 260/390 (66%), Gaps = 5/390 (1%)

Query: 10  SSSSIKGSSGLGGGSSRTSCRLSGGLGAGSCRLGSAGGLGSTLGGSSYSSCYSFGSGGG- 68
           S  +  G +     S  T+C L G      C+  S       L G     CY  GS    
Sbjct: 14  SCGTASGCAPASSCSVETAC-LPGTCATSRCQTPSFLSRSRGLTGCLLP-CYFTGSCNSP 71

Query: 69  --YGSSFGGVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVKIRDWYQRQAPG 126
              G+     DG+    EK TMQ LNDRLASYL+KVR+LEE N ELE +I++  ++  P 
Sbjct: 72  CLVGNCAWCEDGVFTSNEKETMQFLNDRLASYLEKVRSLEETNAELESRIQEQCEQDIPM 131

Query: 127 PARDYSQYYRTIEELQNKILTATVDNANILLQIDNARLAADDFRTKFETEQALRLSVEAD 186
              DY +Y+ TIE+LQ KIL    +N+ + +Q+DN +LA DDF++K+E+E +LR  +EAD
Sbjct: 132 VCPDYQRYFNTIEDLQQKILCTKAENSRLAVQLDNCKLATDDFKSKYESELSLRQLLEAD 191

Query: 187 INGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGEINVEMDAAPG 246
           I+ L  +L+ELTL ++DLE  +E+LKE+L  LKKNHEEE+N LR Q+G  ++VE+D AP 
Sbjct: 192 ISSLHGILEELTLCKSDLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDRLSVELDTAPT 251

Query: 247 VDLSRILNEMRDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQSGKSEISELRRT 306
           +DL+R+L+EMR Q E +   NR++AE+W   +TEELN++  +++E +Q  + EI EL+RT
Sbjct: 252 LDLNRVLDEMRCQCETVLANNRREAEEWLAVQTEELNQQQLSSAEQLQGCQMEILELKRT 311

Query: 307 MQALEIELQSQLSMKASLEGNLAETENRYCVQLSQIQGLIGSVEEQLAQLRCEMEQQNQE 366
             ALEIELQ+Q S+  SLE  +AETE +Y  QL+QIQ LI ++E QLA++RC++E+QNQE
Sbjct: 312 ASALEIELQAQQSLTESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCDLERQNQE 371

Query: 367 YKILLDVKTRLEQEIATYRRLLEGEDAHLT 396
           Y++LLDVK RLE EI TY  LL+ ED+ L+
Sbjct: 372 YQVLLDVKARLEGEINTYWGLLDSEDSRLS 401


>gi|40354195 keratin 18 [Homo sapiens]
          Length = 430

 Score =  329 bits (843), Expect = 3e-90
 Identities = 185/386 (47%), Positives = 261/386 (67%), Gaps = 12/386 (3%)

Query: 45  AGGLGSTLGGSSYSSCYSFGSGGGYGSSFGGVDGLLAG-----GEKATMQNLNDRLASYL 99
           AGG GS +   S S   SF  G G G    G+ G LAG      EK TMQ+LNDRLASYL
Sbjct: 39  AGGSGSRI---SVSRSTSFRGGMGSGGLATGIAGGLAGMGGIQNEKETMQSLNDRLASYL 95

Query: 100 DKVRALEEANTELEVKIRDWYQRQAPGPARDYSQYYRTIEELQNKILTATVDNANILLQI 159
           D+VR+LE  N  LE KIR+  +++ P   RD+S Y++ IE+L+ +I   TVDNA I+LQI
Sbjct: 96  DRVRSLETENRRLESKIREHLEKKGP-QVRDWSHYFKIIEDLRAQIFANTVDNARIVLQI 154

Query: 160 DNARLAADDFRTKFETEQALRLSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLK 219
           DNARLAADDFR K+ETE A+R SVE DI+GLR+V+D+  + R  LE +IE LKEEL ++K
Sbjct: 155 DNARLAADDFRVKYETELAMRQSVENDIHGLRKVIDDTNITRLQLETEIEALKEELLFMK 214

Query: 220 KNHEEEMNALRGQVGGE-INVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEDWFFSK 278
           KNHEEE+  L+ Q+    + VE+DA    DL++I+ ++R QY+++A KNR++ + ++  +
Sbjct: 215 KNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIMADIRAQYDELARKNREELDKYWSQQ 274

Query: 279 TEELNREVATNSELVQSGKSEISELRRTMQALEIELQSQLSMKASLEGNLAETENRYCVQ 338
            EE    V T S  V + ++ ++ELRRT+Q+LEI+L S  ++KASLE +L E E RY +Q
Sbjct: 275 IEESTTVVTTQSAEVGAAETTLTELRRTVQSLEIDLDSMRNLKASLENSLREVEARYALQ 334

Query: 339 LSQIQGLIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLE-GEDAHLTQ 397
           + Q+ G++  +E +LAQ R E ++Q QEY+ LL++K +LE EIATYRRLLE GED +L  
Sbjct: 335 MEQLNGILLHLESELAQTRAEGQRQAQEYEALLNIKVKLEAEIATYRRLLEDGEDFNLGD 394

Query: 398 YKKEPVTTRQV-RTIVEEVQDGKVIS 422
                 + + + +T    + DGKV+S
Sbjct: 395 ALDSSNSMQTIQKTTTRRIVDGKVVS 420


>gi|4557888 keratin 18 [Homo sapiens]
          Length = 430

 Score =  329 bits (843), Expect = 3e-90
 Identities = 185/386 (47%), Positives = 261/386 (67%), Gaps = 12/386 (3%)

Query: 45  AGGLGSTLGGSSYSSCYSFGSGGGYGSSFGGVDGLLAG-----GEKATMQNLNDRLASYL 99
           AGG GS +   S S   SF  G G G    G+ G LAG      EK TMQ+LNDRLASYL
Sbjct: 39  AGGSGSRI---SVSRSTSFRGGMGSGGLATGIAGGLAGMGGIQNEKETMQSLNDRLASYL 95

Query: 100 DKVRALEEANTELEVKIRDWYQRQAPGPARDYSQYYRTIEELQNKILTATVDNANILLQI 159
           D+VR+LE  N  LE KIR+  +++ P   RD+S Y++ IE+L+ +I   TVDNA I+LQI
Sbjct: 96  DRVRSLETENRRLESKIREHLEKKGP-QVRDWSHYFKIIEDLRAQIFANTVDNARIVLQI 154

Query: 160 DNARLAADDFRTKFETEQALRLSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLK 219
           DNARLAADDFR K+ETE A+R SVE DI+GLR+V+D+  + R  LE +IE LKEEL ++K
Sbjct: 155 DNARLAADDFRVKYETELAMRQSVENDIHGLRKVIDDTNITRLQLETEIEALKEELLFMK 214

Query: 220 KNHEEEMNALRGQVGGE-INVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEDWFFSK 278
           KNHEEE+  L+ Q+    + VE+DA    DL++I+ ++R QY+++A KNR++ + ++  +
Sbjct: 215 KNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIMADIRAQYDELARKNREELDKYWSQQ 274

Query: 279 TEELNREVATNSELVQSGKSEISELRRTMQALEIELQSQLSMKASLEGNLAETENRYCVQ 338
            EE    V T S  V + ++ ++ELRRT+Q+LEI+L S  ++KASLE +L E E RY +Q
Sbjct: 275 IEESTTVVTTQSAEVGAAETTLTELRRTVQSLEIDLDSMRNLKASLENSLREVEARYALQ 334

Query: 339 LSQIQGLIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLE-GEDAHLTQ 397
           + Q+ G++  +E +LAQ R E ++Q QEY+ LL++K +LE EIATYRRLLE GED +L  
Sbjct: 335 MEQLNGILLHLESELAQTRAEGQRQAQEYEALLNIKVKLEAEIATYRRLLEDGEDFNLGD 394

Query: 398 YKKEPVTTRQV-RTIVEEVQDGKVIS 422
                 + + + +T    + DGKV+S
Sbjct: 395 ALDSSNSMQTIQKTTTRRIVDGKVVS 420


>gi|148277620 type I hair keratin KA35 [Homo sapiens]
          Length = 491

 Score =  328 bits (840), Expect = 8e-90
 Identities = 183/385 (47%), Positives = 247/385 (64%), Gaps = 41/385 (10%)

Query: 84  EKATMQNLNDRLASYLDKVRALEEANTELEVKIRDWYQRQAPGPARDYSQYYRTIEELQN 143
           EK TMQ LN+RLA+YL KVR LE  N ELE KI++   ++ P    DY  YY TIEELQ 
Sbjct: 96  EKETMQILNERLANYLQKVRMLERENAELESKIQEESNKELPVLCPDYLSYYTTIEELQQ 155

Query: 144 KILTATVDNANILLQIDNARLAADDFRTKFETEQALRLSVEADINGLRRVLDELTLARAD 203
           KIL    +N+ ++ QIDN +L ADD R K+E E +LR  VE+D NGL+++L+ LTL +AD
Sbjct: 156 KILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLVESDANGLKQILNVLTLGKAD 215

Query: 204 LEMQIENLKEELAYLKKNHEEEMNALRGQVGGEINVEMDAAPGVDLSRILNEMRDQYEKM 263
           LE Q+++LKEEL  LK NH+EE+N+L+ Q+G  +++E+ AAP  DL+++L EMR QYE +
Sbjct: 216 LEAQVQSLKEELLCLKNNHKEEINSLQCQLGERLDIEVTAAPSADLNQVLQEMRCQYEPI 275

Query: 264 AEKNRKDAEDWFFSKTEELNREVATNSELVQSGKSEISELRRTMQALEIELQSQLSMKAS 323
            E NRKD E WF ++ EELN++V T+S+  Q  + EI ELRR++  LE+ELQ+Q  M+ S
Sbjct: 276 METNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIELRRSVNTLEVELQAQHRMRDS 335

Query: 324 LEGNLAETENRYCVQLSQIQGLIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIAT 383
            E  L ETE RY   L+QIQ LI ++E QLA++RC +E+QNQEY+ILLDVK+RLE EI T
Sbjct: 336 QECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQNQEYEILLDVKSRLECEITT 395

Query: 384 YRRLLEGEDA------HLTQYKKEPVTT-------------------------------- 405
           YR LLE  D         T+ +  P T+                                
Sbjct: 396 YRSLLESSDGKRPCYPRATKCEPSPWTSCKSGAIESTAPACTSSSPCSLKEHCSACGPLS 455

Query: 406 ---RQVRTIVEEVQDGKVISSREQV 427
               ++ TI +E++DGKVISS E V
Sbjct: 456 RILVKICTITKEIKDGKVISSYEHV 480


>gi|15431318 keratin 38 [Homo sapiens]
          Length = 456

 Score =  325 bits (832), Expect = 6e-89
 Identities = 171/334 (51%), Positives = 236/334 (70%), Gaps = 6/334 (1%)

Query: 62  SFGSGGGYGSSFGGVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVKIRDWYQ 121
           + G  G YG      +  L G EK TMQ LNDRLA+YL+KVR LE+ N ELE  + +  +
Sbjct: 88  NIGICGAYG------ENTLNGHEKETMQFLNDRLANYLEKVRQLEQENAELEATLLERSK 141

Query: 122 RQAPGPARDYSQYYRTIEELQNKILTATVDNANILLQIDNARLAADDFRTKFETEQALRL 181
                   DY  Y+ TIEELQ KIL +  +NA +++QIDNA+LAADDFR K E+E++LR 
Sbjct: 142 CHESTVCPDYQSYFHTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLRQ 201

Query: 182 SVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGEINVEM 241
            VEAD  G +++LD+ TLA+ADLE Q E+LKEE   LK NHE+E+  LR Q+G ++ +E+
Sbjct: 202 LVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKLRIEL 261

Query: 242 DAAPGVDLSRILNEMRDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQSGKSEIS 301
           D  P +DL+R+L EMR QYE M E NR+D E WF +++E ++ +  + SE +Q  +SEI 
Sbjct: 262 DIEPTIDLNRVLGEMRAQYEAMLETNRQDVEQWFQAQSEGISLQDMSCSEELQCCQSEIL 321

Query: 302 ELRRTMQALEIELQSQLSMKASLEGNLAETENRYCVQLSQIQGLIGSVEEQLAQLRCEME 361
           ELR T+ ALE+E Q+Q ++K  L+ +L E E+R+  +L+Q+Q LI +VEEQL+++R ++E
Sbjct: 322 ELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRFGTELAQMQSLISNVEEQLSEIRADLE 381

Query: 362 QQNQEYKILLDVKTRLEQEIATYRRLLEGEDAHL 395
           +QNQEY++LLDVKTRLE EIATYR LLE ED  L
Sbjct: 382 RQNQEYQVLLDVKTRLENEIATYRNLLESEDCKL 415


>gi|55770882 keratin 37 [Homo sapiens]
          Length = 449

 Score =  323 bits (827), Expect = 2e-88
 Identities = 179/391 (45%), Positives = 254/391 (64%), Gaps = 17/391 (4%)

Query: 16  GSSGLGGGSSRTSCRLSGGLGAGSCRLGSA--GGLGSTLGGSSYSSCY---------SFG 64
           G   +   ++ + C L+    A   R+GS   G     L  +S+++C          + G
Sbjct: 31  GCQPVAEANAASMCLLANVAHANRVRVGSTPLGRPSLCLPPTSHTACPLPGTCHIPGNIG 90

Query: 65  SGGGYGSSFGGVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVKIRDWYQRQA 124
             G YG +       L G EK TM+ LNDRLA+YL+KVR LE+ N ELE  + +  +   
Sbjct: 91  ICGAYGKN------TLNGHEKETMKFLNDRLANYLEKVRQLEQENAELETTLLERSKCHE 144

Query: 125 PGPARDYSQYYRTIEELQNKILTATVDNANILLQIDNARLAADDFRTKFETEQALRLSVE 184
                DY  Y+RTIEELQ KIL +  +NA +++QIDNA+LAADDFR K E+E++L   VE
Sbjct: 145 STVCPDYQSYFRTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLHQLVE 204

Query: 185 ADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGEINVEMDAA 244
           AD  G +++LD+ TLA+ADLE Q E+LKEE   LK NHE+E+  LR Q+G +  +E+D  
Sbjct: 205 ADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKFRIELDIE 264

Query: 245 PGVDLSRILNEMRDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQSGKSEISELR 304
           P +DL+R+L EMR QYE M E N +D E WF +++E ++ +  + SE +Q  +SEI ELR
Sbjct: 265 PTIDLNRVLGEMRAQYEAMVETNHQDVEQWFQAQSEGISLQAMSCSEELQCCQSEILELR 324

Query: 305 RTMQALEIELQSQLSMKASLEGNLAETENRYCVQLSQIQGLIGSVEEQLAQLRCEMEQQN 364
            T+ ALE+E Q+Q ++K  L+ +L E E+RY  +L+Q+Q LI ++EEQL+++R ++E+QN
Sbjct: 325 CTVNALEVERQAQHTLKDCLQNSLCEAEDRYGTELAQMQSLISNLEEQLSEIRADLERQN 384

Query: 365 QEYKILLDVKTRLEQEIATYRRLLEGEDAHL 395
           QEY++LLDVK RLE EIATYR LLE ED  L
Sbjct: 385 QEYQVLLDVKARLENEIATYRNLLESEDCKL 415


>gi|27894339 keratin 23 [Homo sapiens]
          Length = 422

 Score =  319 bits (818), Expect = 3e-87
 Identities = 167/379 (44%), Positives = 247/379 (65%), Gaps = 6/379 (1%)

Query: 46  GGLGSTLGGSSYSSCYSFGSGGGYGSSFGGVDGLLAGGEKATMQNLNDRLASYLDKVRAL 105
           GG G      S+++      GG +GS  G    LL G  KATMQNLNDRLASYL+KVRAL
Sbjct: 36  GGAGGARISLSFTTRSCPPPGGSWGS--GRSSPLLGGNGKATMQNLNDRLASYLEKVRAL 93

Query: 106 EEANTELEVKIRDWYQRQAPGPARDYSQYYRTIEELQNKILTATVDNANILLQIDNARLA 165
           EEAN +LE +I  W+Q++ PG  +DYSQY   I  LQ +I+   + NA I+L IDNAR+A
Sbjct: 94  EEANMKLESRILKWHQQRDPGSKKDYSQYEENITHLQEQIVDGKMTNAQIILLIDNARMA 153

Query: 166 ADDFRTKFETEQALRLSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEEE 225
            DDF  K+E E + +  +E ++ GLRR LD LT+   DLE ++E +++EL  +KK+HE+E
Sbjct: 154 VDDFNLKYENEHSFKKDLEIEVEGLRRTLDNLTIVTTDLEQEVEGMRKELILMKKHHEQE 213

Query: 226 MNALRGQVGGEINVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEDWFFSKTEELNRE 285
           M          +NV++D  P  DL ++L +MR +YE + +K  +D + W+  ++  +++E
Sbjct: 214 MEKHHVPSDFNVNVKVDTGPREDLIKVLEDMRQEYELIIKKKHRDLDTWYKEQSAAMSQE 273

Query: 286 VATNSELVQSGKSEISELRRTMQALEIELQSQLSMKASLEGNLAETENRYCVQLSQIQGL 345
            A+ +  VQS + +I EL+RT QALEI+LQ+Q S K++LE  L+ET++RY  +L  +Q +
Sbjct: 274 AASPA-TVQSRQGDIHELKRTFQALEIDLQTQYSTKSALENMLSETQSRYSCKLQDMQEI 332

Query: 346 IGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGEDAHLTQYKKEPV-- 403
           I   EE+L QLR E+E+QN EY++LL +KT LE+EI TYRRLLEGE     +  K  +  
Sbjct: 333 ISHYEEELTQLRHELERQNNEYQVLLGIKTHLEKEITTYRRLLEGESEGTREESKSSMKV 392

Query: 404 -TTRQVRTIVEEVQDGKVI 421
             T +++ I +E  +G+++
Sbjct: 393 SATPKIKAITQETINGRLV 411


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.129    0.346 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,219,150
Number of Sequences: 37866
Number of extensions: 637244
Number of successful extensions: 7788
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 257
Number of HSP's successfully gapped in prelim test: 587
Number of HSP's that attempted gapping in prelim test: 3806
Number of HSP's gapped (non-prelim): 2735
length of query: 432
length of database: 18,247,518
effective HSP length: 105
effective length of query: 327
effective length of database: 14,271,588
effective search space: 4666809276
effective search space used: 4666809276
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.