Search of human proteins with 45505173

Search of human proteins with 45505173

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|45505173 B cell RAG associated protein [Homo sapiens]
         (561 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|45505173 B cell RAG associated protein [Homo sapiens]             1169   0.0  
gi|12007650 heparan sulfate N-deacetylase/N-sulfotransferase 4 [...    59   2e-08
gi|116089312 heparan sulfate (glucosamine) 3-O-sulfotransferase ...    54   4e-07
gi|104876423 heparan sulfate D-glucosaminyl 3-O-sulfotransferase...    53   6e-07
gi|5174467 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3...    52   1e-06
gi|5174465 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3...    52   1e-06
gi|4758766 N-deacetylase/N-sulfotransferase (heparan glucosaminy...    47   5e-05
gi|4505353 heparan glucosaminyl N-deacetylase/N-sulfotransferase...    45   2e-04
gi|5174463 heparan sulfate D-glucosaminyl  3-O-sulfotransferase ...    41   0.003
gi|4505351 N-deacetylase/N-sulfotransferase (heparan glucosaminy...    40   0.004
gi|4826764 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1...    39   0.010
gi|45267824 heparan sulfate (glucosamine) 3-O-sulfotransferase 5...    35   0.18 
gi|24308334 family with sequence similarity 120B [Homo sapiens]        35   0.18 
gi|7657554 dickkopf-like 1 precursor [Homo sapiens]                    30   5.9  
gi|4885099 carbonic anhydrase III [Homo sapiens]                       30   5.9  
gi|111074524 Src homology 2 domain containing F [Homo sapiens]         30   7.7  

>gi|45505173 B cell RAG associated protein [Homo sapiens]
          Length = 561

 Score = 1169 bits (3024), Expect = 0.0
 Identities = 561/561 (100%), Positives = 561/561 (100%)

Query: 1   MRHCINCCIQLLPDGAHKQQVNCQGGPHHGHQACPTCKGENKILFRVDSKQMNLLAVLEV 60
           MRHCINCCIQLLPDGAHKQQVNCQGGPHHGHQACPTCKGENKILFRVDSKQMNLLAVLEV
Sbjct: 1   MRHCINCCIQLLPDGAHKQQVNCQGGPHHGHQACPTCKGENKILFRVDSKQMNLLAVLEV 60

Query: 61  RTEGNENWGGFLRFKKGKRCSLVFGLIIMTLVMASYILSGAHQELLISSPFHYGGFPSNP 120
           RTEGNENWGGFLRFKKGKRCSLVFGLIIMTLVMASYILSGAHQELLISSPFHYGGFPSNP
Sbjct: 61  RTEGNENWGGFLRFKKGKRCSLVFGLIIMTLVMASYILSGAHQELLISSPFHYGGFPSNP 120

Query: 121 SLMDSENPSDTKEHHHQSSVNNISYMKDYPSIKLIINSITTRIEFTTRQLPDLEDLKKQE 180
           SLMDSENPSDTKEHHHQSSVNNISYMKDYPSIKLIINSITTRIEFTTRQLPDLEDLKKQE
Sbjct: 121 SLMDSENPSDTKEHHHQSSVNNISYMKDYPSIKLIINSITTRIEFTTRQLPDLEDLKKQE 180

Query: 181 LHMFSVIPNKFLPNSKSPCWYEEFSGQNTTDPYLTNSYVLYSKRFRSTFDALRKAFWGHL 240
           LHMFSVIPNKFLPNSKSPCWYEEFSGQNTTDPYLTNSYVLYSKRFRSTFDALRKAFWGHL
Sbjct: 181 LHMFSVIPNKFLPNSKSPCWYEEFSGQNTTDPYLTNSYVLYSKRFRSTFDALRKAFWGHL 240

Query: 241 AHAHGKHFRLRCLPHFYIIGQPKCGTTDLYDRLRLHPEVKFSAIKEPHWWTRKRFGIVRL 300
           AHAHGKHFRLRCLPHFYIIGQPKCGTTDLYDRLRLHPEVKFSAIKEPHWWTRKRFGIVRL
Sbjct: 241 AHAHGKHFRLRCLPHFYIIGQPKCGTTDLYDRLRLHPEVKFSAIKEPHWWTRKRFGIVRL 300

Query: 301 RDGLRDRYPVEDYLDLFDLAAHQIHQGLQASSAKEQSKMNTIIIGEASASTMWDNNAWTF 360
           RDGLRDRYPVEDYLDLFDLAAHQIHQGLQASSAKEQSKMNTIIIGEASASTMWDNNAWTF
Sbjct: 301 RDGLRDRYPVEDYLDLFDLAAHQIHQGLQASSAKEQSKMNTIIIGEASASTMWDNNAWTF 360

Query: 361 FYDNSTDGEPPFLTQDFIHAFQPNARLIVMLRDPVERLYSDYLYFASSNKSADDFHEKVT 420
           FYDNSTDGEPPFLTQDFIHAFQPNARLIVMLRDPVERLYSDYLYFASSNKSADDFHEKVT
Sbjct: 361 FYDNSTDGEPPFLTQDFIHAFQPNARLIVMLRDPVERLYSDYLYFASSNKSADDFHEKVT 420

Query: 421 EALQLFENCMLDYSLRACVYNNTLNNAMPVRLQVGLYAVYLLDWLSVFDKQQFLILRLED 480
           EALQLFENCMLDYSLRACVYNNTLNNAMPVRLQVGLYAVYLLDWLSVFDKQQFLILRLED
Sbjct: 421 EALQLFENCMLDYSLRACVYNNTLNNAMPVRLQVGLYAVYLLDWLSVFDKQQFLILRLED 480

Query: 481 HASNVKYTMHKVFQFLNLGPLSEKQEALMTKSPASNARRPEDRNLGPMWPITQKILRDFY 540
           HASNVKYTMHKVFQFLNLGPLSEKQEALMTKSPASNARRPEDRNLGPMWPITQKILRDFY
Sbjct: 481 HASNVKYTMHKVFQFLNLGPLSEKQEALMTKSPASNARRPEDRNLGPMWPITQKILRDFY 540

Query: 541 RPFNARLAQVLADEAFAWKTT 561
           RPFNARLAQVLADEAFAWKTT
Sbjct: 541 RPFNARLAQVLADEAFAWKTT 561


>gi|12007650 heparan sulfate N-deacetylase/N-sulfotransferase 4
           [Homo sapiens]
          Length = 872

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 75/314 (23%), Positives = 117/314 (37%), Gaps = 69/314 (21%)

Query: 253 LPHFYIIGQPKCGTTDLYDRLRLHPEVKFSAIKEPHWWTRKRFGIVRLRDGLRDRYPVED 312
           LP F +IG  K GTT LY  L +HP +  S +  P     K F  V+  +G      ++ 
Sbjct: 594 LPKFLVIGPQKTGTTALYLFLLMHPSI-ISNLPSP-----KTFEEVQFFNGNNYHKGIDW 647

Query: 313 YLDLFDLAAHQIHQGLQASSAKEQSKMNTIIIGEASASTMWDNNAWTFFYDNSTDGEPPF 372
           Y+D F   ++     L   SA                          +F+          
Sbjct: 648 YMDFFPTPSNTTSDFLFEKSAN-------------------------YFHSEEAPRRAAS 682

Query: 373 LTQDFIHAFQPNARLIVMLRDPVERLYSDYLYFASSNKSAD---DFHEKVTEALQLFENC 429
           L         P A++I +L DP +R YS Y +  S    A    +F+E ++       + 
Sbjct: 683 LV--------PKAKIITILIDPSDRAYSWYQHQRSHEDPAALRFNFYEVISTGHWAPSD- 733

Query: 430 MLDYSLRACVYNNTLNNAMPVRLQVGLYAVYLLDWLSVFDKQQFLILRLEDHASNVKYTM 489
            L    R C             L  G YAV++  WL+ F   Q LI+  +   S+    M
Sbjct: 734 -LKTLQRRC-------------LVPGWYAVHIERWLTYFATSQLLIIDGQQLRSDPATVM 779

Query: 490 HKVFQFLNLGPLSEKQEA------------LMTKSPASNARRPEDRNLGPMWPITQKILR 537
            +V +FL + P     EA            L+         + + R   PM P ++  L 
Sbjct: 780 DEVQKFLGVTPRYNYSEALTFDPQKGFWCQLLEGGKTKCLGKSKGRKYPPMDPESRTFLS 839

Query: 538 DFYRPFNARLAQVL 551
           ++YR  N  L+++L
Sbjct: 840 NYYRDHNVELSKLL 853


>gi|116089312 heparan sulfate (glucosamine) 3-O-sulfotransferase 6
           [Homo sapiens]
          Length = 311

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 52/196 (26%), Positives = 81/196 (41%), Gaps = 36/196 (18%)

Query: 378 IHAFQPNARLIVMLRDPVERLYSDYLYFASSNKSADDFHEKVTEALQLFENCMLDYSLRA 437
           IHA  P+ +LIV++R+PV R  SDY    S       F                    RA
Sbjct: 136 IHAMSPDTKLIVVVRNPVTRAISDYAQTLSKTPGLPSF--------------------RA 175

Query: 438 CVYNNTLN--NAMPVRLQVGLYAVYLLDWLSVFDKQQFLILRLEDHASNVKYTMHKVFQF 495
             + + L   +     +++GLYA +L  WL  F    FL +  E   S+    + +V  F
Sbjct: 176 LAFRHGLGPVDTAWSAVRIGLYAQHLDHWLRYFPLSHFLFVSGERLVSDPAGEVGRVQDF 235

Query: 496 LNLGPL---------SEKQEALMTKSPASNARRPEDRNLGPMWP-ITQKILR---DFYRP 542
           L L  +         + K    + K+   +  R   ++ G   P + Q ++R   +FYRP
Sbjct: 236 LGLKRVVTDKHFYFNATKGFPCLKKAQGGSRPRCLGKSKGRPHPRVPQALVRRLQEFYRP 295

Query: 543 FNARLAQVLADEAFAW 558
           FN R  Q+   + F W
Sbjct: 296 FNRRFYQMTGQD-FGW 310



 Score = 33.1 bits (74), Expect = 0.69
 Identities = 18/42 (42%), Positives = 25/42 (59%), Gaps = 1/42 (2%)

Query: 251 RCLPHFYIIGQPKCGTTDLYDRLRLHPEVKFSAIKEPHWWTR 292
           R  P   I+G  K GT  L + LRLHP+V+ +   EPH++ R
Sbjct: 57  RRFPQALIVGVKKGGTRALLEFLRLHPDVR-ALGSEPHFFDR 97


>gi|104876423 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4
           [Homo sapiens]
          Length = 456

 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 76/320 (23%), Positives = 118/320 (36%), Gaps = 79/320 (24%)

Query: 253 LPHFYIIGQPKCGTTDLYDRLRLHPEVKFSAIKEPHWWTRKRFGIVRLRDGLRDRYPVED 312
           LP   IIG  K GT  L + +R+HP+V+   + EPH++ R                    
Sbjct: 197 LPQALIIGVKKGGTRALLEAIRVHPDVRAVGV-EPHFFDR-------------------- 235

Query: 313 YLDLFDLAAHQIHQGLQASSAKEQSKMNTIIIGEASASTMWDNNAWTFFYDNSTDGEPPF 372
                        +GL+         ++  I  E + S    N A    +  + D     
Sbjct: 236 ----------NYEKGLEWYRNVMPKTLDGQITMEKTPSYFVTNEAPKRIHSMAKD----- 280

Query: 373 LTQDFIHAFQPNARLIVMLRDPVERLYSDYLYFASSNKSADDFHEKVTEALQLFENCMLD 432
                        +LIV++R+PV R  SDY    S       F       +  F+N  L 
Sbjct: 281 ------------IKLIVVVRNPVTRAISDYTQTLSKKPEIPTFE------VLAFKNRTLG 322

Query: 433 YSLRACVYNNTLNNAMPVRLQVGLYAVYLLDWLSVFDKQQFLILRLEDHASNVKYTMHKV 492
                      L +A    +++G+YA++L +WL  F   Q L +  E    +    M KV
Sbjct: 323 -----------LIDASWSAIRIGIYALHLENWLQYFPLSQILFVSGERLIVDPAGEMAKV 371

Query: 493 FQFLNLGPLSEKQEALMTKSPASNA-RRPED----RNLGP--------MWPITQKILRDF 539
             FL L  +  ++     K+      ++PED    R LG         + P     LR F
Sbjct: 372 QDFLGLKRVVTEKHFYFNKTKGFPCLKKPEDSSAPRCLGKSKGRTHPRIDPDVIHRLRKF 431

Query: 540 YRPFNARLAQVLADEAFAWK 559
           Y+PFN    Q+   + F W+
Sbjct: 432 YKPFNLMFYQMTGQD-FQWE 450


>gi|5174467 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1
           [Homo sapiens]
          Length = 390

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 56/197 (28%), Positives = 85/197 (43%), Gaps = 37/197 (18%)

Query: 378 IHAFQPNARLIVMLRDPVERLYSDYLYFASSNKSADDFHEKVTEALQLFEN---CMLDYS 434
           I A   + +LIV++RDPV R  SDY    S       F E +T     F+N    ++D S
Sbjct: 214 ISAMSKDTKLIVVVRDPVTRAISDYTQTLSKRPDIPTF-ESLT-----FKNRTAGLIDTS 267

Query: 435 LRACVYNNTLNNAMPVRLQVGLYAVYLLDWLSVFDKQQFLILRLEDHASNVKYTMHKVFQ 494
             A              +Q+G+YA +L  WL  F  +Q L +  E   S+    + +V  
Sbjct: 268 WSA--------------IQIGIYAKHLEHWLRHFPIRQMLFVSGERLISDPAGELGRVQD 313

Query: 495 FLNLGPLSEKQEALMTKS-------PASNARRPE--DRNLGPMWP-ITQKI---LRDFYR 541
           FL L  +   +     K+        A  + RP    +  G   P I +++   LR+FYR
Sbjct: 314 FLGLKRIITDKHFYFNKTKGFPCLKKAEGSSRPHCLGKTKGRTHPEIDREVVRRLREFYR 373

Query: 542 PFNARLAQVLADEAFAW 558
           PFN +  Q+   + F W
Sbjct: 374 PFNLKFYQMTGHD-FGW 389



 Score = 33.1 bits (74), Expect = 0.69
 Identities = 18/40 (45%), Positives = 25/40 (62%), Gaps = 1/40 (2%)

Query: 253 LPHFYIIGQPKCGTTDLYDRLRLHPEVKFSAIKEPHWWTR 292
           LP   IIG  K GT  L + LR+HP+V+ +   EPH++ R
Sbjct: 137 LPQAIIIGVKKGGTRALLEFLRVHPDVR-AVGAEPHFFDR 175


>gi|5174465 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1
           [Homo sapiens]
          Length = 406

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 56/197 (28%), Positives = 85/197 (43%), Gaps = 37/197 (18%)

Query: 378 IHAFQPNARLIVMLRDPVERLYSDYLYFASSNKSADDFHEKVTEALQLFEN---CMLDYS 434
           I A   + +LIV++RDPV R  SDY    S       F E +T     F+N    ++D S
Sbjct: 229 ISAMSKDTKLIVVVRDPVTRAISDYTQTLSKRPDIPTF-ESLT-----FKNRTAGLIDTS 282

Query: 435 LRACVYNNTLNNAMPVRLQVGLYAVYLLDWLSVFDKQQFLILRLEDHASNVKYTMHKVFQ 494
             A              +Q+G+YA +L  WL  F  +Q L +  E   S+    + +V  
Sbjct: 283 WSA--------------IQIGIYAKHLEHWLRHFPIRQMLFVSGERLISDPAGELGRVQD 328

Query: 495 FLNLGPLSEKQEALMTKS-------PASNARRPE--DRNLGPMWP-ITQKI---LRDFYR 541
           FL L  +   +     K+        A  + RP    +  G   P I +++   LR+FYR
Sbjct: 329 FLGLKRIITDKHFYFNKTKGFPCLKKAEGSSRPHCLGKTKGRTHPEIDREVVRRLREFYR 388

Query: 542 PFNARLAQVLADEAFAW 558
           PFN +  Q+   + F W
Sbjct: 389 PFNLKFYQMTGHD-FGW 404



 Score = 33.1 bits (74), Expect = 0.69
 Identities = 18/40 (45%), Positives = 25/40 (62%), Gaps = 1/40 (2%)

Query: 253 LPHFYIIGQPKCGTTDLYDRLRLHPEVKFSAIKEPHWWTR 292
           LP   IIG  K GT  L + LR+HP+V+ +   EPH++ R
Sbjct: 152 LPQAIIIGVKKGGTRALLEFLRVHPDVR-AVGAEPHFFDR 190


>gi|4758766 N-deacetylase/N-sulfotransferase (heparan glucosaminyl)
           3 [Homo sapiens]
          Length = 873

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 73/311 (23%), Positives = 115/311 (36%), Gaps = 63/311 (20%)

Query: 253 LPHFYIIGQPKCGTTDLYDRLRLHPEVKFSAIKEPHWWTRKRFGIVRLRDGLRDRYPVED 312
           LP F +IG  K GTT LY  L +HP +  S    P     K F  V+  +       ++ 
Sbjct: 595 LPKFLVIGPQKTGTTALYLFLVMHPSI-LSNSPSP-----KTFEEVQFFNRNNYHRGIDW 648

Query: 313 YLDLFDLAAHQIHQGLQASSAKEQSKMNTIIIGEASASTMWDNNAWTFFYDNSTDGEPPF 372
           Y+D F +                 S + T  + E SA+         +F+          
Sbjct: 649 YMDFFPV----------------PSNVTTDFLFEKSAN---------YFHSEEAPKRAAS 683

Query: 373 LTQDFIHAFQPNARLIVMLRDPVERLYSDYLYFASSNKSADDFHEKVTEALQLFENCMLD 432
           L         P A++I +L DP +R YS Y +  S    A         AL+     ++ 
Sbjct: 684 LV--------PKAKIITILIDPSDRAYSWYQHQRSHEDPA---------ALKFSFYEVIS 726

Query: 433 YSLRACVYNNTLNNAMPVRLQVGLYAVYLLDWLSVFDKQQFLILRLEDHASNVKYTMHKV 492
              RA    + L       L  G YA ++  WL  F   Q LI+  +   ++    M +V
Sbjct: 727 AGPRA---PSELRALQKRCLVPGWYASHIERWLVYFPPFQLLIIDGQQLRTDPATVMDEV 783

Query: 493 FQFLNLGPLSEKQEA------------LMTKSPASNARRPEDRNLGPMWPITQKILRDFY 540
            +FL + P     EA            L+ +       + + R   PM   ++  L  +Y
Sbjct: 784 QKFLGVLPHYNYSEALTFDSHKGFWCQLLEEGKTKCLGKSKGRKYPPMDSDSRTFLSSYY 843

Query: 541 RPFNARLAQVL 551
           R  N  L+++L
Sbjct: 844 RDHNVELSKLL 854


>gi|4505353 heparan glucosaminyl N-deacetylase/N-sulfotransferase 2
           [Homo sapiens]
          Length = 883

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 65/312 (20%), Positives = 119/312 (38%), Gaps = 63/312 (20%)

Query: 253 LPHFYIIGQPKCGTTDLYDRLRLHPEVKFSAIKEPHWWTRKRFGIVRLRDGLRDRYPVED 312
           LP F I+G  K GTT ++  L LHP V  S+   P       F  ++  +       ++ 
Sbjct: 603 LPKFLIVGPQKTGTTAIHFFLSLHPAVT-SSFPSP-----STFEEIQFFNSPNYHKGIDW 656

Query: 313 YLDLFDLAAHQIHQGLQASSAKEQSKMNTIIIGEASASTMWDNNAWTFFYDNSTDGEPPF 372
           Y+D F + ++                        AS   +++ +A T+F           
Sbjct: 657 YMDFFPVPSN------------------------ASTDFLFEKSA-TYFDSEVVPRRGA- 690

Query: 373 LTQDFIHAFQPNARLIVMLRDPVERLYSDYLYFASSNKSADDFHEKVTEALQLFENCMLD 432
                  A  P A++I +L +P +R YS Y +  +              AL      ++ 
Sbjct: 691 -------ALLPRAKIITVLTNPADRAYSWYQHQRAHGDPV---------ALNYTFYQVIS 734

Query: 433 YSLRACVYNNTLNNAMPVRLQVGLYAVYLLDWLSVFDKQQFLILRLEDHASNVKYTMHKV 492
            S +  +   +L N     L  G Y+ +L  WL+ +   Q LI+  ++  +N   +M  +
Sbjct: 735 ASSQTPLALRSLQNRC---LVPGYYSTHLQRWLTYYPSGQLLIVDGQELRTNPAASMESI 791

Query: 493 FQFLNLGPL--------SEKQEALMTKSPASNARRPEDRNLGPMWP----ITQKILRDFY 540
            +FL + P          +  +    +       R   R+ G  +P     ++  L DF+
Sbjct: 792 QKFLGITPFLNYTRTLRFDDDKGFWCQGLEGGKTRCLGRSKGRRYPDMDTESRLFLTDFF 851

Query: 541 RPFNARLAQVLA 552
           R  N  L+++L+
Sbjct: 852 RNHNLELSKLLS 863


>gi|5174463 heparan sulfate D-glucosaminyl  3-O-sulfotransferase 2
           [Homo sapiens]
          Length = 367

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 69/334 (20%), Positives = 119/334 (35%), Gaps = 85/334 (25%)

Query: 242 HAHGKHFRLRCLPHFYIIGQPKCGTTDLYDRLRLHPEVKFSAIKEPHWWTRKRFGIVRLR 301
           H+       + LP   I+G  K GT  + + +R+HP+V+ +   EPH++ R  +G     
Sbjct: 103 HSGSPKLGTKRLPQALIVGVKKGGTRAVLEFIRVHPDVR-ALGTEPHFFDR-NYG----- 155

Query: 302 DGLRDRYPVEDYLDLFDLAAHQIHQGLQASSAKEQSKMNTIIIGEASASTMWDNNAWTFF 361
                                   +GL    +     + + I  E + S      A    
Sbjct: 156 ------------------------RGLDWYRSLMPRTLESQITLEKTPSYFVTQEAPRRI 191

Query: 362 YDNSTDGEPPFLTQDFIHAFQPNARLIVMLRDPVERLYSDYLYFASSNKSADDFHEKVTE 421
           ++ S D                  +LIV++R+PV R  SDY    S       F     E
Sbjct: 192 FNMSRD-----------------TKLIVVVRNPVTRAISDYTQTLSKKPDIPTF-----E 229

Query: 422 ALQLFEN---CMLDYSLRACVYNNTLNNAMPVRLQVGLYAVYLLDWLSVFDKQQFLILRL 478
            L  F N    ++D S  A              +++G+Y ++L  WL  F   Q   +  
Sbjct: 230 GLS-FRNRTLGLVDVSWNA--------------IRIGMYVLHLESWLQYFPLAQIHFVSG 274

Query: 479 EDHASNVKYTMHKVFQFLNLGPLSEKQEALMTKSPASNARRPEDRNLGP----------- 527
           E   ++    M +V  FL +      +     K+      +  + +L P           
Sbjct: 275 ERLITDPAGEMGRVQDFLGIKRFITDKHFYFNKTKGFPCLKKTESSLLPRCLGKSKGRTH 334

Query: 528 --MWPITQKILRDFYRPFNARLAQVLADEAFAWK 559
             + P     LR+FYRP+N +  + +  + F W+
Sbjct: 335 VQIDPEVIDQLREFYRPYNIKFYETVGQD-FRWE 367


>gi|4505351 N-deacetylase/N-sulfotransferase (heparan glucosaminyl)
           1 [Homo sapiens]
          Length = 882

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 64/317 (20%), Positives = 115/317 (36%), Gaps = 77/317 (24%)

Query: 254 PHFYIIGQPKCGTTDLYDRLRLHPEVKFSAIKEPHWWTRKRFGIVRLRDGLRDRYPVEDY 313
           P   IIG  K GTT LY  L +HP++        ++ + + F  ++  +G      ++ Y
Sbjct: 605 PKLLIIGPQKTGTTALYLFLGMHPDLS------SNYPSSETFEEIQFFNGHNYHKGIDWY 658

Query: 314 LDLFDLAAHQIHQGLQASSAKEQSKMNTIIIGEASASTMWDNNAWTFFYDNSTDGEPPFL 373
           ++ F + +                                 N    F+++ S +     +
Sbjct: 659 MEFFPIPS---------------------------------NTTSDFYFEKSANYFDSEV 685

Query: 374 TQDFIHAFQPNARLIVMLRDPVERLYSDYLYFASSNKSADD-------FHEKVTEALQLF 426
                 A  P A+++ +L +P +R YS Y +     ++ DD       FHE +T      
Sbjct: 686 APRRAAALLPKAKVLTILINPADRAYSWYQH----QRAHDDPVALKYTFHEVITAGSDAS 741

Query: 427 ENCMLDYSLRACVYNNTLNNAMPVRLQVGLYAVYLLDWLSVFDKQQFLILRLEDHASNVK 486
                   LRA      L N     L  G YA ++  WLS +   Q L+L  +   +   
Sbjct: 742 SK------LRA------LQNRC---LVPGWYATHIERWLSAYHANQILVLDGKLLRTEPA 786

Query: 487 YTMHKVFQFLNLGPLSEKQEA------------LMTKSPASNARRPEDRNLGPMWPITQK 534
             M  V +FL +    +  +             L+         + + R    M   ++ 
Sbjct: 787 KVMDMVQKFLGVTNTIDYHKTLAFDPKKGFWCQLLEGGKTKCLGKSKGRKYPEMDLDSRA 846

Query: 535 ILRDFYRPFNARLAQVL 551
            L+D+YR  N  L+++L
Sbjct: 847 FLKDYYRDHNIELSKLL 863


>gi|4826764 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1
           precursor [Homo sapiens]
          Length = 307

 Score = 39.3 bits (90), Expect = 0.010
 Identities = 30/123 (24%), Positives = 52/123 (42%), Gaps = 16/123 (13%)

Query: 378 IHAFQPNARLIVMLRDPVERLYSDYLYFASSNKSADDFHEKVTEALQLFENCMLDYSLRA 437
           +++  P+ RL+++LRDP ER+ SDY     ++      +  + E L       +DY    
Sbjct: 133 VYSMNPSIRLLLILRDPSERVLSDYTQVFYNHMQKHKPYPSIEEFLVRDGRLNVDYK--- 189

Query: 438 CVYNNTLNNAMPVRLQVGLYAVYLLDWLSVFDKQQFLILRLEDHASNVKYTMHKVFQFLN 497
                         L   LY V++ +WL  F  +   I+  +    +    + KV +FL 
Sbjct: 190 -------------ALNRSLYHVHMQNWLRFFPLRHIHIVDGDRLIRDPFPEIQKVERFLK 236

Query: 498 LGP 500
           L P
Sbjct: 237 LSP 239


>gi|45267824 heparan sulfate (glucosamine) 3-O-sulfotransferase 5
           [Homo sapiens]
          Length = 346

 Score = 35.0 bits (79), Expect = 0.18
 Identities = 39/193 (20%), Positives = 72/193 (37%), Gaps = 28/193 (14%)

Query: 372 FLTQDF---IHAFQPNARLIVMLRDPVERLYSDYLYFASSNKSADDFHEKVTEALQLFEN 428
           F+T++    I+    + +L++++R+P  R  SDY              E+  +    FE 
Sbjct: 160 FITEEVPERIYKMNSSIKLLIIVREPTTRAISDYTQVLEGK-------ERKNKTYYKFEK 212

Query: 429 CMLDYSLRACVYNNTLNNAMPVRLQVGLYAVYLLDWLSVFDKQQFLILRLEDHASNVKYT 488
             +D +   C  N          ++  +Y  +L  WL  F  +QF ++  +   +     
Sbjct: 213 LAIDPN--TCEVNTKYK-----AVRTSIYTKHLERWLKYFPIEQFHVVDGDRLITEPLPE 265

Query: 489 MHKVFQFLNLGPLSEKQEALMTKSPASNARR-----------PEDRNLGPMWPITQKILR 537
           +  V +FLNL P   +       +      R            + R    + P     LR
Sbjct: 266 LQLVEKFLNLPPRISQYNLYFNATRGFYCLRFNIIFNKCLAGSKGRIHPEVDPSVITKLR 325

Query: 538 DFYRPFNARLAQV 550
            F+ PFN +  Q+
Sbjct: 326 KFFHPFNQKFYQI 338


>gi|24308334 family with sequence similarity 120B [Homo sapiens]
          Length = 910

 Score = 35.0 bits (79), Expect = 0.18
 Identities = 35/105 (33%), Positives = 49/105 (46%), Gaps = 16/105 (15%)

Query: 417 EKVTEALQLFENCMLDYSLRACVYNNTLNNAMPVRLQVGLYAVYLLDWLSV---FDKQQF 473
           EK+ E+L L   C+ D  L AC+  N +   +P  +        L  + SV   FDK+  
Sbjct: 209 EKLCESLGL---CVADLPLLACLLGNDI---IPEGMFESFRYKCLSSYTSVKENFDKKGN 262

Query: 474 LILRLEDHASNVKYTMH---KVFQFLNLGPLSEKQEALMTKSPAS 515
           +IL + DH S V Y      K+ + L LGP     +AL  K  AS
Sbjct: 263 IILAVSDHISKVLYLYQGEKKLEEILPLGP----NKALFYKGMAS 303


>gi|7657554 dickkopf-like 1 precursor [Homo sapiens]
          Length = 242

 Score = 30.0 bits (66), Expect = 5.9
 Identities = 17/43 (39%), Positives = 20/43 (46%), Gaps = 12/43 (27%)

Query: 275 LHPEVKFSAIKEP------------HWWTRKRFGIVRLRDGLR 305
           LHP V F  IK P            HW + KR  +  +RDGLR
Sbjct: 163 LHPRVAFWIIKLPRRRSHQDALEGGHWLSEKRHRLQAIRDGLR 205


>gi|4885099 carbonic anhydrase III [Homo sapiens]
          Length = 260

 Score = 30.0 bits (66), Expect = 5.9
 Identities = 16/59 (27%), Positives = 25/59 (42%)

Query: 26 GPHHGHQACPTCKGENKILFRVDSKQMNLLAVLEVRTEGNENWGGFLRFKKGKRCSLVF 84
          GP H H+  P  KGEN+    + +K +     L+  +   +          GK C +VF
Sbjct: 12 GPDHWHELFPNAKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKTILNNGKTCRVVF 70


>gi|111074524 Src homology 2 domain containing F [Homo sapiens]
          Length = 423

 Score = 29.6 bits (65), Expect = 7.7
 Identities = 16/37 (43%), Positives = 22/37 (59%), Gaps = 2/37 (5%)

Query: 285 KEPHWWTRKRFGIVRLRDGLRDR--YPVEDYLDLFDL 319
           K+ +W +  R  I+RLRD L  R    +EDY D FD+
Sbjct: 78  KKSNWRSTTRLRIIRLRDRLEPRPLAILEDYADPFDV 114


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.137    0.430 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,525,800
Number of Sequences: 37866
Number of extensions: 945886
Number of successful extensions: 2227
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 2193
Number of HSP's gapped (non-prelim): 28
length of query: 561
length of database: 18,247,518
effective HSP length: 107
effective length of query: 454
effective length of database: 14,195,856
effective search space: 6444918624
effective search space used: 6444918624
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.