Guide to the Human Genome
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Name: PLEKHG4 Sequence: fasta or formatted (1110aa) NCBI GI: 193211603
Description:

pleckstrin homology domain containing, family G (with RhoGef domain) member 4 isoform 2

Referenced in:

Inositol Pathways
Additional Serine / Threonine Protein Kinases

Other entries for this name:
alt prot [1191aa] pleckstrin homology domain containing, family G (with RhoGef doma...
alt prot [1191aa] pleckstrin homology domain containing, family G (with RhoGef doma...
alt prot [1191aa] pleckstrin homology domain containing, family G (with RhoGef doma...
alt prot [1191aa] pleckstrin homology domain containing, family G (with RhoGef doma...
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine            10.1        112           2
 C cysteine            2.5         28           2
 D aspartate           4.4         49           1
 E glutamate           7.6         84           4
 F phenylalanine       3.2         35           2
 G glycine             6.7         74           3
 H histidine           2.7         30           2
 I isoleucine          1.7         19           1
 K lysine              2.5         28           1
 L leucine            14.1        156           3
 M methionine          1.6         18           1
 N asparagine          1.6         18           1
 P proline             6.7         74           3
 Q glutamine           7.4         82           2
 R arginine            7.1         79           3
 S serine              7.9         88           3
 T threonine           3.3         37           1
 V valine              5.3         59           2
 W tryptophan          1.7         19           1
 Y tyrosine            1.9         21           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   pleckstrin homology domain containing, family G (wi... 
PLEKHG4               0.912   pleckstrin homology domain containing, family G (wi...
PLEKHG4               0.912   pleckstrin homology domain containing, family G (wi...
PLEKHG4               0.912   pleckstrin homology domain containing, family G (wi...
PLEKHG4               0.912   pleckstrin homology domain containing, family G (wit...
PLEKHG4B              0.182   pleckstrin homology domain containing, family G (wi...
FLJ10357              0.162   hypothetical protein LOC55701 
TRIO                  0.076   triple functional domain (PTPRF interacting) 
MCF2L                 0.074   MCF.2 cell line derived transforming sequence-like ...
MCF2L                 0.074   MCF.2 cell line derived transforming sequence-like ...
KIAA1755              0.071   hypothetical protein LOC85449 
KALRN                 0.071   kalirin, RhoGEF kinase isoform 1 
KALRN                 0.071   kalirin, RhoGEF kinase isoform 3 
KALRN                 0.069   kalirin, RhoGEF kinase isoform 2 
MCF2                  0.068   MCF.2 cell line derived transforming sequence isofo...
MCF2                  0.068   MCF.2 cell line derived transforming sequence isofo...
GEFT                  0.068   RhoA/RAC/CDC42 exchange factor isoform 1 
GEFT                  0.068   RhoA/RAC/CDC42 exchange factor isoform 3 
MCF2L2                0.046   Rho family guanine-nucleotide exchange factor 
PLEKHG1               0.045   pleckstrin homology domain containing, family G (wit...
OBSCN                 0.040   obscurin, cytoskeletal calmodulin and titin-interact...
OBSCN                 0.040   obscurin, cytoskeletal calmodulin and titin-interac...
PLEKHG3               0.024   pleckstrin homology domain containing, family G, mem...
PLEKHG2               0.024   common-site lymphoma/leukemia guanine nucleotide ex...
PREX1                 0.022   phosphatidylinositol-3,4,5-trisphosphate-dependent R...
FGD4                  0.019   FYVE, RhoGEF and PH domain containing 4 
DNMBP                 0.019   dynamin binding protein 
FGD2                  0.016   FYVE, RhoGEF and PH domain containing 2 
VAV1                  0.016   vav 1 guanine nucleotide exchange factor 
TIAM1                 0.016   T-cell lymphoma invasion and metastasis 1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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