Search of human proteins with 45439355

Search of human proteins with 45439355

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|45439355 transcription elongation factor A 1 isoform 2 [Homo
sapiens]
         (280 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|45439355 transcription elongation factor A 1 isoform 2 [Homo ...   560   e-160
gi|5803191 transcription elongation factor A 1 isoform 1 [Homo s...   547   e-156
gi|239749424 PREDICTED: hypothetical protein XP_002347041 [Homo ...   520   e-148
gi|4507385 transcription elongation factor A protein 2 isoform a...   352   2e-97
gi|38505156 transcription elongation factor A protein 2 isoform ...   340   8e-94
gi|41350335 transcription elongation factor A (SII), 3 [Homo sap...   304   5e-83
gi|154146187 TFIIS central domain-containing protein 1 [Homo sap...   117   1e-26
gi|7662018 PHD finger protein 3 [Homo sapiens]                         74   2e-13
gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]       52   6e-07
gi|71044477 death inducer-obliterator 1 isoform b [Homo sapiens]       52   6e-07
gi|47271475 SPOC domain containing 1 [Homo sapiens]                    51   1e-06
gi|7706499 DNA directed RNA polymerase III polypeptide K [Homo s...    49   4e-06
gi|28558977 mediator complex subunit 26 [Homo sapiens]                 40   0.002
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]    39   0.004
gi|23308505 hypothetical protein LOC127428 [Homo sapiens]              38   0.011
gi|110349775 zinc finger protein 12 isoform b [Homo sapiens]           35   0.056
gi|66348108 zinc finger protein 12 isoform a [Homo sapiens]            35   0.056
gi|55769548 PHD finger protein 14 isoform 2 [Homo sapiens]             35   0.073
gi|55769550 PHD finger protein 14 isoform 1 [Homo sapiens]             35   0.073
gi|221136803 zinc finger protein 776 [Homo sapiens]                    34   0.12 
gi|23097321 zinc finger protein 383 [Homo sapiens]                     34   0.12 
gi|50428917 epithelial stromal interaction 1 isoform 1 [Homo sap...    34   0.12 
gi|29337290 melanoma antigen family B, 6 [Homo sapiens]                34   0.16 
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]     33   0.21 
gi|32698748 zinc finger protein 248 [Homo sapiens]                     33   0.21 
gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Ho...    33   0.28 
gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo...    33   0.28 
gi|26080431 ATPase family, AAA domain containing 5 [Homo sapiens]      33   0.28 
gi|87116683 proline/serine-rich coiled-coil 2 [Homo sapiens]           33   0.28 
gi|197245440 hypothetical protein LOC23285 [Homo sapiens]              33   0.28 

>gi|45439355 transcription elongation factor A 1 isoform 2 [Homo
           sapiens]
          Length = 280

 Score =  560 bits (1442), Expect = e-160
 Identities = 280/280 (100%), Positives = 280/280 (100%)

Query: 1   MEDEVVRFAKKMDKMVQKKNASTRIGMSVNAIRKQSTDEEVTSLAKSLIKSWKKLLDGPS 60
           MEDEVVRFAKKMDKMVQKKNASTRIGMSVNAIRKQSTDEEVTSLAKSLIKSWKKLLDGPS
Sbjct: 1   MEDEVVRFAKKMDKMVQKKNASTRIGMSVNAIRKQSTDEEVTSLAKSLIKSWKKLLDGPS 60

Query: 61  TEKDLDEKKKEPAITSQNSPEAREESTSSGNVSNRKDETNARDTYVSSFPRAPSTSDSVR 120
           TEKDLDEKKKEPAITSQNSPEAREESTSSGNVSNRKDETNARDTYVSSFPRAPSTSDSVR
Sbjct: 61  TEKDLDEKKKEPAITSQNSPEAREESTSSGNVSNRKDETNARDTYVSSFPRAPSTSDSVR 120

Query: 121 LKCREMLAAALRTGDDYIAIGADEEELGSQIEEAIYQEIRNTDMKYKNRVRSRISNLKDA 180
           LKCREMLAAALRTGDDYIAIGADEEELGSQIEEAIYQEIRNTDMKYKNRVRSRISNLKDA
Sbjct: 121 LKCREMLAAALRTGDDYIAIGADEEELGSQIEEAIYQEIRNTDMKYKNRVRSRISNLKDA 180

Query: 181 KNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRKNLTKEAIREHQMAKTGGTQTDLF 240
           KNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRKNLTKEAIREHQMAKTGGTQTDLF
Sbjct: 181 KNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRKNLTKEAIREHQMAKTGGTQTDLF 240

Query: 241 TCGKCKKKNCTYTQVQTRSADEPMTTFVVCNECGNRWKFC 280
           TCGKCKKKNCTYTQVQTRSADEPMTTFVVCNECGNRWKFC
Sbjct: 241 TCGKCKKKNCTYTQVQTRSADEPMTTFVVCNECGNRWKFC 280


>gi|5803191 transcription elongation factor A 1 isoform 1 [Homo
           sapiens]
          Length = 301

 Score =  547 bits (1410), Expect = e-156
 Identities = 280/301 (93%), Positives = 280/301 (93%), Gaps = 21/301 (6%)

Query: 1   MEDEVVRFAKKMDKMVQKKNA---------------------STRIGMSVNAIRKQSTDE 39
           MEDEVVRFAKKMDKMVQKKNA                     STRIGMSVNAIRKQSTDE
Sbjct: 1   MEDEVVRFAKKMDKMVQKKNAAGALDLLKELKNIPMTLELLQSTRIGMSVNAIRKQSTDE 60

Query: 40  EVTSLAKSLIKSWKKLLDGPSTEKDLDEKKKEPAITSQNSPEAREESTSSGNVSNRKDET 99
           EVTSLAKSLIKSWKKLLDGPSTEKDLDEKKKEPAITSQNSPEAREESTSSGNVSNRKDET
Sbjct: 61  EVTSLAKSLIKSWKKLLDGPSTEKDLDEKKKEPAITSQNSPEAREESTSSGNVSNRKDET 120

Query: 100 NARDTYVSSFPRAPSTSDSVRLKCREMLAAALRTGDDYIAIGADEEELGSQIEEAIYQEI 159
           NARDTYVSSFPRAPSTSDSVRLKCREMLAAALRTGDDYIAIGADEEELGSQIEEAIYQEI
Sbjct: 121 NARDTYVSSFPRAPSTSDSVRLKCREMLAAALRTGDDYIAIGADEEELGSQIEEAIYQEI 180

Query: 160 RNTDMKYKNRVRSRISNLKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRKNL 219
           RNTDMKYKNRVRSRISNLKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRKNL
Sbjct: 181 RNTDMKYKNRVRSRISNLKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRKNL 240

Query: 220 TKEAIREHQMAKTGGTQTDLFTCGKCKKKNCTYTQVQTRSADEPMTTFVVCNECGNRWKF 279
           TKEAIREHQMAKTGGTQTDLFTCGKCKKKNCTYTQVQTRSADEPMTTFVVCNECGNRWKF
Sbjct: 241 TKEAIREHQMAKTGGTQTDLFTCGKCKKKNCTYTQVQTRSADEPMTTFVVCNECGNRWKF 300

Query: 280 C 280
           C
Sbjct: 301 C 301


>gi|239749424 PREDICTED: hypothetical protein XP_002347041 [Homo
           sapiens]
          Length = 287

 Score =  520 bits (1340), Expect = e-148
 Identities = 266/287 (92%), Positives = 266/287 (92%), Gaps = 21/287 (7%)

Query: 15  MVQKKNA---------------------STRIGMSVNAIRKQSTDEEVTSLAKSLIKSWK 53
           MVQKKNA                     STRIGMSVNAIRKQSTDEEVTSLAKSLIKSWK
Sbjct: 1   MVQKKNAAGALDLLKELKNIPMTLELLQSTRIGMSVNAIRKQSTDEEVTSLAKSLIKSWK 60

Query: 54  KLLDGPSTEKDLDEKKKEPAITSQNSPEAREESTSSGNVSNRKDETNARDTYVSSFPRAP 113
           KLLDGPSTEKDLDEKKKEPAITSQNSPEAREESTSSGNVSNRKDETNARDTYVSSFPRAP
Sbjct: 61  KLLDGPSTEKDLDEKKKEPAITSQNSPEAREESTSSGNVSNRKDETNARDTYVSSFPRAP 120

Query: 114 STSDSVRLKCREMLAAALRTGDDYIAIGADEEELGSQIEEAIYQEIRNTDMKYKNRVRSR 173
           STSDSVRLKCREMLAAALRTGDDYIAIGADEEELGSQIEEAIYQEIRNTDMKYKNRVRSR
Sbjct: 121 STSDSVRLKCREMLAAALRTGDDYIAIGADEEELGSQIEEAIYQEIRNTDMKYKNRVRSR 180

Query: 174 ISNLKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRKNLTKEAIREHQMAKTG 233
           ISNLKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRKNLTKEAIREHQMAKTG
Sbjct: 181 ISNLKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRKNLTKEAIREHQMAKTG 240

Query: 234 GTQTDLFTCGKCKKKNCTYTQVQTRSADEPMTTFVVCNECGNRWKFC 280
           GTQTDLFTCGKCKKKNCTYTQVQTRSADEPMTTFVVCNECGNRWKFC
Sbjct: 241 GTQTDLFTCGKCKKKNCTYTQVQTRSADEPMTTFVVCNECGNRWKFC 287


>gi|4507385 transcription elongation factor A protein 2 isoform a
           [Homo sapiens]
          Length = 299

 Score =  352 bits (904), Expect = 2e-97
 Identities = 187/301 (62%), Positives = 223/301 (74%), Gaps = 28/301 (9%)

Query: 2   EDEVVRFAKKMDKMVQKKNA---------------------STRIGMSVNAIRKQSTDEE 40
           E+E+ R A+++DKMV KK+A                     STR+GMSVNA+RKQS+DEE
Sbjct: 5   EEEIARIARRLDKMVTKKSAEGAMDLLRELKAMPITLHLLQSTRVGMSVNALRKQSSDEE 64

Query: 41  VTSLAKSLIKSWKKLLDGPSTEKDLDEKKKEPAITSQNSPEAREESTSSGNVSNRKDETN 100
           V +LAKSLIKSWKKLLD  S  K  +  +  P  TS     +R+ S +      R +   
Sbjct: 65  VIALAKSLIKSWKKLLDA-SDAKARERGRGMPLPTS-----SRDASEAPDPSRKRPELPR 118

Query: 101 ARDT-YVSSFPRAPSTSDSVRLKCREMLAAALRTGDDYIAIGADEEELGSQIEEAIYQEI 159
           A  T  +++FP  P T D+VR KCREML AAL+T  D++AIGAD E L +QIEE I++++
Sbjct: 119 APSTPRITTFPPVPVTCDAVRNKCREMLTAALQTDHDHVAIGADCERLSAQIEECIFRDV 178

Query: 160 RNTDMKYKNRVRSRISNLKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRKNL 219
            NTDMKYKNRVRSRISNLKDAKNP+LR+NVLCG I P   A MT+EEMASDELKE+RK +
Sbjct: 179 GNTDMKYKNRVRSRISNLKDAKNPDLRRNVLCGAITPQQIAVMTSEEMASDELKEIRKAM 238

Query: 220 TKEAIREHQMAKTGGTQTDLFTCGKCKKKNCTYTQVQTRSADEPMTTFVVCNECGNRWKF 279
           TKEAIREHQMA+TGGTQTDLFTCGKC+KKNCTYTQVQTRS+DEPMTTFVVCNECGNRWKF
Sbjct: 239 TKEAIREHQMARTGGTQTDLFTCGKCRKKNCTYTQVQTRSSDEPMTTFVVCNECGNRWKF 298

Query: 280 C 280
           C
Sbjct: 299 C 299


>gi|38505156 transcription elongation factor A protein 2 isoform b
           [Homo sapiens]
          Length = 272

 Score =  340 bits (872), Expect = 8e-94
 Identities = 176/260 (67%), Positives = 206/260 (79%), Gaps = 7/260 (2%)

Query: 22  STRIGMSVNAIRKQSTDEEVTSLAKSLIKSWKKLLDGPSTEKDLDEKKKEPAITSQNSPE 81
           STR+GMSVNA+RKQS+DEEV +LAKSLIKSWKKLLD  S  K  +  +  P  TS     
Sbjct: 19  STRVGMSVNALRKQSSDEEVIALAKSLIKSWKKLLDA-SDAKARERGRGMPLPTS----- 72

Query: 82  AREESTSSGNVSNRKDETNARDT-YVSSFPRAPSTSDSVRLKCREMLAAALRTGDDYIAI 140
           +R+ S +      R +   A  T  +++FP  P T D+VR KCREML AAL+T  D++AI
Sbjct: 73  SRDASEAPDPSRKRPELPRAPSTPRITTFPPVPVTCDAVRNKCREMLTAALQTDHDHVAI 132

Query: 141 GADEEELGSQIEEAIYQEIRNTDMKYKNRVRSRISNLKDAKNPNLRKNVLCGNIPPDLFA 200
           GAD E L +QIEE I++++ NTDMKYKNRVRSRISNLKDAKNP+LR+NVLCG I P   A
Sbjct: 133 GADCERLSAQIEECIFRDVGNTDMKYKNRVRSRISNLKDAKNPDLRRNVLCGAITPQQIA 192

Query: 201 RMTAEEMASDELKEMRKNLTKEAIREHQMAKTGGTQTDLFTCGKCKKKNCTYTQVQTRSA 260
            MT+EEMASDELKE+RK +TKEAIREHQMA+TGGTQTDLFTCGKC+KKNCTYTQVQTRS+
Sbjct: 193 VMTSEEMASDELKEIRKAMTKEAIREHQMARTGGTQTDLFTCGKCRKKNCTYTQVQTRSS 252

Query: 261 DEPMTTFVVCNECGNRWKFC 280
           DEPMTTFVVCNECGNRWKFC
Sbjct: 253 DEPMTTFVVCNECGNRWKFC 272


>gi|41350335 transcription elongation factor A (SII), 3 [Homo
           sapiens]
          Length = 348

 Score =  304 bits (779), Expect = 5e-83
 Identities = 170/345 (49%), Positives = 212/345 (61%), Gaps = 66/345 (19%)

Query: 2   EDEVVRFAKKMDKMVQKKNA---------------------STRIGMSVNAIRKQSTDEE 40
           E+E++R AKK++KMV +KN                      +TRIG++VN +RK  +D+E
Sbjct: 4   EEELLRIAKKLEKMVARKNTEGALDLLKKLHSCQMSIQLLQTTRIGVAVNGVRKHCSDKE 63

Query: 41  VTSLAKSLIKSWKKLLDGPSTEKDLDEKKKEPAITSQNSPEAREESTSSGNVSNRK---D 97
           V SLAK LIK+WK+LLD P   K    +++E A   +   E  +    +G    RK   D
Sbjct: 64  VVSLAKVLIKNWKRLLDSPGPPKGEKGEEREKAKKKEKGLECSDWKPEAGLSPPRKKRED 123

Query: 98  ETNARDTY-----VSSFPRAPS-------------------------------------T 115
               RD+       SS P+ PS                                     T
Sbjct: 124 PKTRRDSVDSKSSASSSPKRPSVERSNSSKSKAESPKTPSSPLTPTFASSMCLLAPCYLT 183

Query: 116 SDSVRLKCREMLAAALRTGDDYIAIGADEEELGSQIEEAIYQEIRNTDMKYKNRVRSRIS 175
            DSVR KC EML+AAL+  DDY   G + +++ S+IE+ IYQE+++TDMKY+NRVRSRIS
Sbjct: 184 GDSVRDKCVEMLSAALKADDDYKDYGVNCDKMASEIEDHIYQELKSTDMKYRNRVRSRIS 243

Query: 176 NLKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRKNLTKEAIREHQMAKTGGT 235
           NLKD +NP LR+NVL G I   L A+MTAEEMASDEL+E+R  +T+EAIREHQMAKTGGT
Sbjct: 244 NLKDPRNPGLRRNVLSGAISAGLIAKMTAEEMASDELRELRNAMTQEAIREHQMAKTGGT 303

Query: 236 QTDLFTCGKCKKKNCTYTQVQTRSADEPMTTFVVCNECGNRWKFC 280
            TDLF C KCKKKNCTY QVQTRSADEPMTTFV+CNECGNRWKFC
Sbjct: 304 TTDLFQCSKCKKKNCTYNQVQTRSADEPMTTFVLCNECGNRWKFC 348


>gi|154146187 TFIIS central domain-containing protein 1 [Homo
           sapiens]
          Length = 381

 Score =  117 bits (292), Expect = 1e-26
 Identities = 87/296 (29%), Positives = 141/296 (47%), Gaps = 27/296 (9%)

Query: 5   VVRFAKKMDKMVQKKNASTRIGMSVNAIRKQSTDEEVTSLAKSLIKSWKKLLDGPSTEKD 64
           V R  K    +  KK A   +     A+ KQ+  +   S     ++  K+   GPS +  
Sbjct: 82  VYRVLKNCPSVALKKKAKCLLS-KWKAVYKQTHSKARNSPKLFPVRGNKEENSGPSHDPS 140

Query: 65  LDEKKKEPAITSQNSPEAREESTSSGNV--SNRKDETNARDTYV------SSFPRAPSTS 116
            +E      I S NS  +++ +  S  +   NR  +   ++ +       S+  R+    
Sbjct: 141 QNETL---GICSSNSLSSQDVAKLSEMIVPENRAIQLKPKEEHFGDGDPESTGKRSSELL 197

Query: 117 DS---VRLKCREMLAAALRTGDDYIAIGADEEELGSQIEEAIYQEIRNTDMKYKNRVRSR 173
           D    +R KC E+L AAL +           +    +IEE ++        KYK  +RS+
Sbjct: 198 DPTTPMRTKCIELLYAALTSSSTDQPKADLWQNFAREIEEHVFTLYSKNIKKYKTCIRSK 257

Query: 174 ISNLKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRKNLTKEAIREHQMAKT- 232
           ++NLK+ +N +L++N+L G   P  FA MT  EMA+ ELK++R + T+  I+EH + +  
Sbjct: 258 VANLKNPRNSHLQQNLLSGTTSPREFAEMTVMEMANKELKQLRASYTESCIQEHYLPQVI 317

Query: 233 GGTQTDLFTCGKCKKKNCTYT-----------QVQTRSADEPMTTFVVCNECGNRW 277
            GTQT+   C +C+K NC  T            V+  + DE M T+V+CNECG +W
Sbjct: 318 DGTQTNKIKCRRCEKYNCKVTVIDRGTLFLPSWVRNSNPDEQMMTYVICNECGEQW 373


>gi|7662018 PHD finger protein 3 [Homo sapiens]
          Length = 2039

 Score = 73.6 bits (179), Expect = 2e-13
 Identities = 50/168 (29%), Positives = 82/168 (48%), Gaps = 4/168 (2%)

Query: 60   STEKDLDEKKKEPAITSQNSPEAREESTSSGNVSNRKDETNARDTYVSSFPRAPSTSDSV 119
            S EK     K+   +T      ++  +     +  +K E    + + ++    PS +D +
Sbjct: 869  SEEKSEKIPKESTTVTCTGEKASKPGTHEKQEMKKKKVEKGVLNVHPAASASKPS-ADQI 927

Query: 120  RLKCREMLAAAL--RTGDDYIAIGADEE-ELGSQIEEAIYQEIRNTDMKYKNRVRSRISN 176
            R   R  L   L  R  D  + +  ++  ++ ++IE+ ++   R+TD KYKN+ RS + N
Sbjct: 928  RQSVRHSLKDILMKRLTDSNLKVPEEKAAKVATKIEKELFSFFRDTDAKYKNKYRSLMFN 987

Query: 177  LKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRKNLTKEAI 224
            LKD KN  L K VL G + PD   RM+ EE+AS EL   R+   +  I
Sbjct: 988  LKDPKNNILFKKVLKGEVTPDHLIRMSPEELASKELAAWRRRENRHTI 1035


>gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]
          Length = 2240

 Score = 52.0 bits (123), Expect = 6e-07
 Identities = 33/114 (28%), Positives = 57/114 (50%), Gaps = 2/114 (1%)

Query: 106 VSSFPRAPSTS--DSVRLKCREMLAAALRTGDDYIAIGADEEELGSQIEEAIYQEIRNTD 163
           +S+ P  P++    ++R   +E+L   +   DD I    +  ++   IE+ ++   + TD
Sbjct: 659 MSAAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTD 718

Query: 164 MKYKNRVRSRISNLKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRK 217
            +YK++ RS + NLKD KN  L   VL   I      R+  EE+ S EL   ++
Sbjct: 719 NRYKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKE 772


>gi|71044477 death inducer-obliterator 1 isoform b [Homo sapiens]
          Length = 1189

 Score = 52.0 bits (123), Expect = 6e-07
 Identities = 33/114 (28%), Positives = 57/114 (50%), Gaps = 2/114 (1%)

Query: 106 VSSFPRAPSTS--DSVRLKCREMLAAALRTGDDYIAIGADEEELGSQIEEAIYQEIRNTD 163
           +S+ P  P++    ++R   +E+L   +   DD I    +  ++   IE+ ++   + TD
Sbjct: 659 MSAAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTD 718

Query: 164 MKYKNRVRSRISNLKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRK 217
            +YK++ RS + NLKD KN  L   VL   I      R+  EE+ S EL   ++
Sbjct: 719 NRYKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKE 772


>gi|47271475 SPOC domain containing 1 [Homo sapiens]
          Length = 1216

 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 38/160 (23%), Positives = 70/160 (43%), Gaps = 7/160 (4%)

Query: 65  LDEKKKEPAITSQNSPEAREESTSSGNVSNRKDETNARDTYVSSFPRAPSTSDSVRLKCR 124
           L +   +PA +     EA E+S       + + +      Y+           +V    +
Sbjct: 565 LGDPSSDPACSQSGPMEAEEDSLPEQPEDSAQLQQEKPSLYIG-------VRGTVVRSMQ 617

Query: 125 EMLAAALRTGDDYIAIGADEEELGSQIEEAIYQEIRNTDMKYKNRVRSRISNLKDAKNPN 184
           E+L   LR   D +      E + + IE A++   + T+ +YK + RS + NL+D +N +
Sbjct: 618 EVLWTRLRELPDPVLSEEVVEGIAAGIEAALWDLTQGTNGRYKTKYRSLLFNLRDPRNLD 677

Query: 185 LRKNVLCGNIPPDLFARMTAEEMASDELKEMRKNLTKEAI 224
           L   V+ G++ P    RM++ ++A  EL   R    K  +
Sbjct: 678 LFLKVVHGDVTPYDLVRMSSMQLAPQELARWRDQEEKRGL 717


>gi|7706499 DNA directed RNA polymerase III polypeptide K [Homo
           sapiens]
          Length = 108

 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 21/40 (52%), Positives = 28/40 (70%), Gaps = 2/40 (5%)

Query: 241 TCGKCKKKNCTYTQVQTRSADEPMTTFVVC--NECGNRWK 278
           +C KC+     + Q+QTRSADEPMTTF  C   +CG+RW+
Sbjct: 68  SCPKCEHPRAYFMQLQTRSADEPMTTFYKCCNAQCGHRWR 107


>gi|28558977 mediator complex subunit 26 [Homo sapiens]
          Length = 600

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 19/55 (34%), Positives = 34/55 (61%), Gaps = 2/55 (3%)

Query: 5  VVRFAKKMDKMVQKKNA--STRIGMSVNAIRKQSTDEEVTSLAKSLIKSWKKLLD 57
          V+     ++K    K A   TR+G  +N +RK++ +EE+   AK L++SW+KL++
Sbjct: 31 VLEVISSLEKYPITKEALEETRLGKLINDVRKKTKNEELAKRAKKLLRSWQKLIE 85


>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
          Length = 1684

 Score = 39.3 bits (90), Expect = 0.004
 Identities = 38/181 (20%), Positives = 76/181 (41%), Gaps = 25/181 (13%)

Query: 2   EDEVVRFAKKMDKMVQK-KNASTRIGMSVNAIRKQSTDEEVTSLAKSLIKSWKK-LLDGP 59
           ++++++FAKK   ++QK K+  T +   +  +R +   E    + K+L +     LL+  
Sbjct: 27  KEDLIKFAKKQMMLIQKAKSRCTELEKEIEELRSKPVTEGTGDIIKALTERLDALLLEKA 86

Query: 60  STEKDLDEKKKEPAITSQNSPEAREESTSSGNVSNRKDETNARDTYVSSFPRAPSTSDSV 119
            TE+     KKE     Q   E  +  T  G+     ++++    YV       +   +V
Sbjct: 87  ETEQQCLSLKKENIKMKQ---EVEDSVTKMGDAHKELEQSHI--NYVKEIENLKNELMAV 141

Query: 120 RLKCREMLAAALRTGDDYIAIGADEEELGSQIEEAIYQEIR-NTDMKYKNRVRSRISNLK 178
           R K  E                 D+  L  Q+EEA+  ++  +  +K++N     +  L+
Sbjct: 142 RSKYSE-----------------DKANLQKQLEEAMNTQLELSEQLKFQNNSEDNVKKLQ 184

Query: 179 D 179
           +
Sbjct: 185 E 185


>gi|23308505 hypothetical protein LOC127428 [Homo sapiens]
          Length = 208

 Score = 37.7 bits (86), Expect = 0.011
 Identities = 24/77 (31%), Positives = 40/77 (51%), Gaps = 4/77 (5%)

Query: 2   EDEVVRFAKKMDKMVQKKNA--STRIGMSVNAIRKQSTDEEVTSLAKSLIKSWKKLLDGP 59
           ++ +V   +++ K +  +    STRIG +VN +RK S D EV SLA+ +   WK   +  
Sbjct: 56  KENLVEALQELKKKIPSREVLKSTRIGHTVNKMRKHS-DSEVASLAREVYTEWKTFTEKH 114

Query: 60  STEKDLDEKKKEPAITS 76
           S    + E + +P   S
Sbjct: 115 SNRPSI-EVRSDPKTES 130


>gi|110349775 zinc finger protein 12 isoform b [Homo sapiens]
          Length = 659

 Score = 35.4 bits (80), Expect = 0.056
 Identities = 19/55 (34%), Positives = 28/55 (50%), Gaps = 5/55 (9%)

Query: 221 KEAIREHQMAKTGGTQTDLFTCGKC-KKKNCTYTQVQTRSADEPMTTFVVCNECG 274
           K A+ +HQ   TG        CGKC  +K+   T ++T + ++P      CNECG
Sbjct: 355 KSALNDHQKIHTGVKLYKCSECGKCFCRKSTLTTHLRTHTGEKPYE----CNECG 405



 Score = 32.0 bits (71), Expect = 0.62
 Identities = 18/54 (33%), Positives = 26/54 (48%), Gaps = 7/54 (12%)

Query: 223 AIREHQMAKTGGTQTDLFTCGKCKKKNCTYTQVQTR--SADEPMTTFVVCNECG 274
           A+  HQ   TG    + + CGKC  +  +Y  +  R  S ++P      CNECG
Sbjct: 553 ALNRHQRTHTGEKAYECYECGKCFSQ-MSYLTIHHRIHSGEKPFE----CNECG 601


>gi|66348108 zinc finger protein 12 isoform a [Homo sapiens]
          Length = 697

 Score = 35.4 bits (80), Expect = 0.056
 Identities = 19/55 (34%), Positives = 28/55 (50%), Gaps = 5/55 (9%)

Query: 221 KEAIREHQMAKTGGTQTDLFTCGKC-KKKNCTYTQVQTRSADEPMTTFVVCNECG 274
           K A+ +HQ   TG        CGKC  +K+   T ++T + ++P      CNECG
Sbjct: 393 KSALNDHQKIHTGVKLYKCSECGKCFCRKSTLTTHLRTHTGEKPYE----CNECG 443



 Score = 32.0 bits (71), Expect = 0.62
 Identities = 18/54 (33%), Positives = 26/54 (48%), Gaps = 7/54 (12%)

Query: 223 AIREHQMAKTGGTQTDLFTCGKCKKKNCTYTQVQTR--SADEPMTTFVVCNECG 274
           A+  HQ   TG    + + CGKC  +  +Y  +  R  S ++P      CNECG
Sbjct: 591 ALNRHQRTHTGEKAYECYECGKCFSQ-MSYLTIHHRIHSGEKPFE----CNECG 639


>gi|55769548 PHD finger protein 14 isoform 2 [Homo sapiens]
          Length = 888

 Score = 35.0 bits (79), Expect = 0.073
 Identities = 28/90 (31%), Positives = 47/90 (52%), Gaps = 9/90 (10%)

Query: 34  KQSTDEEVTSLAKSLIKSWKKLL----DGPSTEKDLDEKKKEPAITSQNSPEAREESTSS 89
           K S +EEV S  K LIK  KK      + P  +K+ +++K++     +   + +E++T S
Sbjct: 82  KNSAEEEVLSSEKQLIKMEKKEEEENGERPRKKKEKEKEKEKEKEKEKEREKEKEKATVS 141

Query: 90  GNVSNRKDETNARDTYVSSFPRAPSTSDSV 119
            NV+      +A  T  ++ P A +TS SV
Sbjct: 142 ENVA-----ASAAATTPATSPPAVNTSPSV 166


>gi|55769550 PHD finger protein 14 isoform 1 [Homo sapiens]
          Length = 948

 Score = 35.0 bits (79), Expect = 0.073
 Identities = 28/90 (31%), Positives = 47/90 (52%), Gaps = 9/90 (10%)

Query: 34  KQSTDEEVTSLAKSLIKSWKKLL----DGPSTEKDLDEKKKEPAITSQNSPEAREESTSS 89
           K S +EEV S  K LIK  KK      + P  +K+ +++K++     +   + +E++T S
Sbjct: 82  KNSAEEEVLSSEKQLIKMEKKEEEENGERPRKKKEKEKEKEKEKEKEKEREKEKEKATVS 141

Query: 90  GNVSNRKDETNARDTYVSSFPRAPSTSDSV 119
            NV+      +A  T  ++ P A +TS SV
Sbjct: 142 ENVA-----ASAAATTPATSPPAVNTSPSV 166


>gi|221136803 zinc finger protein 776 [Homo sapiens]
          Length = 518

 Score = 34.3 bits (77), Expect = 0.12
 Identities = 23/66 (34%), Positives = 28/66 (42%), Gaps = 6/66 (9%)

Query: 211 ELKEMRKNLT-KEAIREHQMAKTGGTQTDLFTCGKC-KKKNCTYTQVQTRSADEPMTTFV 268
           E KE RK+   K  + EHQ   TG    +   CGKC  +K       Q  S + P     
Sbjct: 405 ECKECRKSFRYKSHLTEHQRVHTGERPYECRECGKCFHQKGSLIQHQQIHSGERPHE--- 461

Query: 269 VCNECG 274
            C ECG
Sbjct: 462 -CGECG 466


>gi|23097321 zinc finger protein 383 [Homo sapiens]
          Length = 475

 Score = 34.3 bits (77), Expect = 0.12
 Identities = 22/71 (30%), Positives = 30/71 (42%), Gaps = 4/71 (5%)

Query: 211 ELKEMRKNLTKEA-IREHQMAKTGGTQTDLFTCGKCKKKNCTYTQVQTRSADEPMTTFVV 269
           + KE  K  T+ + +R+HQ    G    +   CGK   +N    Q Q    DE       
Sbjct: 367 DCKECGKAFTQSSQLRQHQRIHAGEKPFECLECGKAFTQNSQLFQHQRIHTDEKP---YE 423

Query: 270 CNECGNRWKFC 280
           CNECG  +  C
Sbjct: 424 CNECGKAFNKC 434


>gi|50428917 epithelial stromal interaction 1 isoform 1 [Homo
           sapiens]
          Length = 410

 Score = 34.3 bits (77), Expect = 0.12
 Identities = 32/135 (23%), Positives = 54/135 (40%), Gaps = 30/135 (22%)

Query: 148 GSQIEEAIYQ--EIRNTDMKYKNRVRSR--ISNLKDAKNPNLRKNVLCGNIPPDLFARMT 203
           GSQ E  + Q  +++    KYK +++    +   K+A+   L+K          + A   
Sbjct: 112 GSQSETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQK----------MKAIQR 161

Query: 204 AEEMASDELKEMRKNLTKEAIREHQMAKTGGTQTDLFTCGKCKKKNCTYTQVQTRSADEP 263
            +    +E K +++NL +EA REHQ  KT                    +++ T S D  
Sbjct: 162 EKSNKLEEKKRLQENLRREAFREHQQYKTAE----------------FLSKLNTESPDRS 205

Query: 264 MTTFVVCNECGNRWK 278
                VC    + WK
Sbjct: 206 ACQSAVCGPQSSTWK 220


>gi|29337290 melanoma antigen family B, 6 [Homo sapiens]
          Length = 407

 Score = 33.9 bits (76), Expect = 0.16
 Identities = 34/178 (19%), Positives = 69/178 (38%), Gaps = 20/178 (11%)

Query: 18  KKNASTRIGMSVNAIRKQSTDEEVTSLAKSLIKSWKKLLDGPSTEKDLDEKKKEPAITSQ 77
           ++++   I      +    + + V S +KS + +  +    PST +D    ++    +  
Sbjct: 53  RRSSDASIPQESQGVSPTGSPDAVVSYSKSDVAANGQDEKSPSTSRDASVPQESQGASPT 112

Query: 78  NSPEAREESTSSGNVSNRKDETNARDTYVSSFPRAPSTSDSVRLKCREMLAAALRTGD-- 135
            SP+A    +     +N +DE            ++PSTS  V +      A+   + D  
Sbjct: 113 GSPDAGVSGSKYDVAANGQDE------------KSPSTSHDVSVPQESQGASPTGSPDAG 160

Query: 136 ------DYIAIGADEEELGSQIEEAIYQEIRNTDMKYKNRVRSRISNLKDAKNPNLRK 187
                 D  A G DEE + +  +  I++ +    +K K    ++    K  K  ++ K
Sbjct: 161 VSGSKYDVAAEGEDEESVSASQKAIIFKRLSKDAVKKKACTLAQFLQKKFEKKESILK 218


>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
          Length = 484

 Score = 33.5 bits (75), Expect = 0.21
 Identities = 26/93 (27%), Positives = 38/93 (40%), Gaps = 2/93 (2%)

Query: 10  KKMDKMVQKKNASTRIGMSVNAIRKQSTDEEVTSLAKSLIKSWKKLLDGPSTEKDLDEKK 69
           KK  K   K  ++ R   S +  R++      T   K      +KL   PS  +   EKK
Sbjct: 320 KKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKK 379

Query: 70  KEPAITSQNSPEAREESTSSGNVSNRKDETNAR 102
           K+     + S + RE STS    S  K++   R
Sbjct: 380 KDK--DKERSRDERERSTSKKKKSKDKEKDRER 410


>gi|32698748 zinc finger protein 248 [Homo sapiens]
          Length = 579

 Score = 33.5 bits (75), Expect = 0.21
 Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 10/73 (13%)

Query: 211 ELKEMRKNL-TKEAIREHQMAKTGGTQTDLFTCGK--CKKKNCTYTQVQTRSADEPMTTF 267
           E K+  K    K  + EHQ   TG    +   CGK  C +   T  Q +T + ++P    
Sbjct: 437 ECKQCGKTFCVKSNLTEHQRTHTGEKPYECNACGKSFCHRSALTVHQ-RTHTGEKPF--- 492

Query: 268 VVCNECGNRWKFC 280
            +CNECG    FC
Sbjct: 493 -ICNECGK--SFC 502



 Score = 28.1 bits (61), Expect = 8.9
 Identities = 22/64 (34%), Positives = 26/64 (40%), Gaps = 3/64 (4%)

Query: 211 ELKEMRKNLTKEAIREHQMAKTGGTQTDLFTCGKCKKKNCTYTQVQTRSADEPMTTFVVC 270
           E K   K   K A+ +HQ+   GG   D    G    K    TQ+  R A     TF  C
Sbjct: 326 EYKVSDKTWEKSALLKHQIVHMGGKSYDYNENGSNFSKKSHLTQL--RRAHTGEKTF-EC 382

Query: 271 NECG 274
            ECG
Sbjct: 383 GECG 386


>gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Homo
           sapiens]
          Length = 1632

 Score = 33.1 bits (74), Expect = 0.28
 Identities = 47/214 (21%), Positives = 84/214 (39%), Gaps = 42/214 (19%)

Query: 62  EKDLDEKKKEPAITSQNS-----PEAREESTSSGNVSNRKDETNARDTYVSSFPRAPSTS 116
           E+D D+ +K   +TS+       P    E   SG  + +++E   RD       R+ +  
Sbjct: 211 EEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEE---RDEKEEKRLRSQTKE 267

Query: 117 DSVRLKCREMLAAALRTGDDYIAIGADEEELGSQIEEAIYQEIRNTDMKYKNRVRSRISN 176
            + + K +E      R G     + ADE+E G              D K + + RS+  +
Sbjct: 268 PTPKQKLKEEPDREARAG-----VQADEDEDG--------------DEKDEKKHRSQPKD 308

Query: 177 LKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRKNLTKEAIREHQMAKTG--- 233
           L   + P  ++        P+      ++E   DE +E R+  T +   E +MA+     
Sbjct: 309 LAAKRRPEEKE--------PEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVM 360

Query: 234 GTQTDLFTCGKCKK----KNCTYTQVQTRSADEP 263
            ++T    C +C +     +  Y Q    + DEP
Sbjct: 361 NSKTHPPKCIQCGQYLDDPDLKYGQHPPDAVDEP 394



 Score = 31.2 bits (69), Expect = 1.1
 Identities = 21/90 (23%), Positives = 41/90 (45%), Gaps = 4/90 (4%)

Query: 34  KQSTDEEVTSLAKSLIKSWKKLLDGPSTEKDLDEKKKEPA-ITSQNSPEAREESTSSGNV 92
           KQ   EE    A++ +++ +   D    EKD  + + +P  + ++  PE +E    +  +
Sbjct: 271 KQKLKEEPDREARAGVQADE---DEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQI 327

Query: 93  SNRKDETNARDTYVSSFPRAPSTSDSVRLK 122
           S+ KDE    +    + P+ P+     R K
Sbjct: 328 SDEKDEDEKEEKRRKTTPKEPTEKKMARAK 357


>gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo
           sapiens]
          Length = 1616

 Score = 33.1 bits (74), Expect = 0.28
 Identities = 47/214 (21%), Positives = 84/214 (39%), Gaps = 42/214 (19%)

Query: 62  EKDLDEKKKEPAITSQNS-----PEAREESTSSGNVSNRKDETNARDTYVSSFPRAPSTS 116
           E+D D+ +K   +TS+       P    E   SG  + +++E   RD       R+ +  
Sbjct: 195 EEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEE---RDEKEEKRLRSQTKE 251

Query: 117 DSVRLKCREMLAAALRTGDDYIAIGADEEELGSQIEEAIYQEIRNTDMKYKNRVRSRISN 176
            + + K +E      R G     + ADE+E G              D K + + RS+  +
Sbjct: 252 PTPKQKLKEEPDREARAG-----VQADEDEDG--------------DEKDEKKHRSQPKD 292

Query: 177 LKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRKNLTKEAIREHQMAKTG--- 233
           L   + P  ++        P+      ++E   DE +E R+  T +   E +MA+     
Sbjct: 293 LAAKRRPEEKE--------PEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVM 344

Query: 234 GTQTDLFTCGKCKK----KNCTYTQVQTRSADEP 263
            ++T    C +C +     +  Y Q    + DEP
Sbjct: 345 NSKTHPPKCIQCGQYLDDPDLKYGQHPPDAVDEP 378



 Score = 31.2 bits (69), Expect = 1.1
 Identities = 21/90 (23%), Positives = 41/90 (45%), Gaps = 4/90 (4%)

Query: 34  KQSTDEEVTSLAKSLIKSWKKLLDGPSTEKDLDEKKKEPA-ITSQNSPEAREESTSSGNV 92
           KQ   EE    A++ +++ +   D    EKD  + + +P  + ++  PE +E    +  +
Sbjct: 255 KQKLKEEPDREARAGVQADE---DEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQI 311

Query: 93  SNRKDETNARDTYVSSFPRAPSTSDSVRLK 122
           S+ KDE    +    + P+ P+     R K
Sbjct: 312 SDEKDEDEKEEKRRKTTPKEPTEKKMARAK 341


>gi|26080431 ATPase family, AAA domain containing 5 [Homo sapiens]
          Length = 1844

 Score = 33.1 bits (74), Expect = 0.28
 Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 8/115 (6%)

Query: 28   SVNAIRKQSTDEEVTSLAKSLIKSWKKLL----DGPSTEKDLDEKKKEPAITSQNSPEAR 83
            S+N + ++ ++ E   L KS  K  KK L    D    + DLD   +  +++S +S    
Sbjct: 1543 SMNCLARKHSERE-QPLKKSQKKKQKKTLVILDDSDLFDTDLDFPDQSISLSSVSSSSNA 1601

Query: 84   EESTSSGNVSNRKDETNARDTYVSSFPRAPSTSDSVRLKCREMLAAALRTGDDYI 138
            EES +    S  +D+ N  +T   S P  P T  +   KC  +++  L +  +++
Sbjct: 1602 EESKTGDEESKARDKGNNPET-KKSIPCPPKT--TAGKKCSALVSHCLNSLSEFM 1653


>gi|87116683 proline/serine-rich coiled-coil 2 [Homo sapiens]
          Length = 1989

 Score = 33.1 bits (74), Expect = 0.28
 Identities = 29/123 (23%), Positives = 59/123 (47%), Gaps = 6/123 (4%)

Query: 2   EDEVVRFAKKMDKMVQKKNASTRIGMSV--NAIRKQSTDEEVTSLAKSLIKSWKKLLDGP 59
           E +V++ +K  +K+ + K    ++  S   ++ +K ST  +  +L K   K+WKKL    
Sbjct: 390 EQQVMKESK--EKLTKTKTVQQKVKTSTKTHSAKKVSTTAK-QALRKQQTKAWKKLQQQK 446

Query: 60  STEKDLDEKKKEPAITSQNSPEAREESTSSGNVSNRKDETNARDTYVSSFPRAPSTSDSV 119
             E+  +E +++ A   +   +  EE     ++SN++++ N     V    R+ S S   
Sbjct: 447 EQERQKEEDQRKQA-EEEERRKREEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSKSSDP 505

Query: 120 RLK 122
            L+
Sbjct: 506 DLR 508


>gi|197245440 hypothetical protein LOC23285 [Homo sapiens]
          Length = 1354

 Score = 33.1 bits (74), Expect = 0.28
 Identities = 17/63 (26%), Positives = 38/63 (60%), Gaps = 2/63 (3%)

Query: 20   NASTRIGMSVNAIRKQSTDEEVTSLAKSLIKSWKKLLDGPSTEKDLDEKKK--EPAITSQ 77
            ++S +   SV+A  K++T + ++S ++ L++  KK+ +G + E D+ ++ K  +  + SQ
Sbjct: 1083 DSSRKNKQSVSATEKKNTIDVLSSRSRQLLREDKKVNNGSNVENDIQQRSKFLDSDVKSQ 1142

Query: 78   NSP 80
              P
Sbjct: 1143 ERP 1145


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.125    0.348 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,125,431
Number of Sequences: 37866
Number of extensions: 443552
Number of successful extensions: 2304
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 36
Number of HSP's successfully gapped in prelim test: 137
Number of HSP's that attempted gapping in prelim test: 2153
Number of HSP's gapped (non-prelim): 305
length of query: 280
length of database: 18,247,518
effective HSP length: 101
effective length of query: 179
effective length of database: 14,423,052
effective search space: 2581726308
effective search space used: 2581726308
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.