Guide to the Human Genome
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Search of human proteins with 45387953

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|45387953 potassium channel tetramerization domain containing
18 [Homo sapiens]
         (426 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|45387953 potassium channel tetramerization domain containing ...   862   0.0  
gi|71143104 potassium channel tetramerisation domain containing ...    82   9e-16
gi|189571693 potassium channel tetramerisation domain containing...    75   1e-13
gi|189571691 potassium channel tetramerisation domain containing...    75   1e-13
gi|19923973 potassium channel tetramerisation domain containing ...    68   1e-11
gi|23308551 potassium channel tetramerisation domain containing ...    65   1e-10
gi|55926200 potassium channel tetramerisation domain containing ...    64   3e-10
gi|10863937 tumor necrosis factor, alpha-induced protein 1 [Homo...    62   8e-10
gi|146198864 potassium channel tetramerisation domain containing...    62   8e-10
gi|13994353 potassium channel tetramerisation domain containing ...    61   2e-09
gi|38198663 potassium channel tetramerisation domain containing ...    60   4e-09
gi|39753959 potassium channel tetramerisation domain containing ...    55   9e-08
gi|40807368 potassium channel regulator isoform 2 [Homo sapiens]       55   1e-07
gi|27734697 potassium channel regulator isoform 1 [Homo sapiens]       55   1e-07
gi|218505694 potassium channel tetramerisation domain containing...    54   2e-07
gi|209969708 potassium channel tetramerisation domain containing...    54   2e-07
gi|40217617 potassium channel tetramerisation domain containing ...    54   2e-07
gi|46255026 potassium channel tetramerisation domain containing ...    54   2e-07
gi|30578412 potassium channel tetramerisation domain containing ...    54   2e-07
gi|169234778 potassium channel tetramerisation domain containing...    53   5e-07
gi|223005950 SH3KBP1 binding protein 1 [Homo sapiens]                  53   5e-07
gi|194018443 potassium channel tetramerisation domain containing...    52   8e-07
gi|194018441 potassium channel tetramerisation domain containing...    52   8e-07
gi|194018439 potassium channel tetramerisation domain containing...    52   8e-07
gi|9506651 potassium channel tetramerisation domain containing 5...    49   9e-06
gi|142356950 potassium channel tetramerisation domain containing...    49   9e-06
gi|53829365 potassium channel tetramerisation domain containing ...    47   3e-05
gi|169184031 PREDICTED: similar to potassium channel tetramerisa...    46   6e-05
gi|169179790 PREDICTED: similar to potassium channel tetramerisa...    46   6e-05
gi|169180181 PREDICTED: similar to potassium channel tetramerisa...    46   6e-05

>gi|45387953 potassium channel tetramerization domain containing 18
           [Homo sapiens]
          Length = 426

 Score =  862 bits (2228), Expect = 0.0
 Identities = 426/426 (100%), Positives = 426/426 (100%)

Query: 1   MEGHKAEEEVLDVLRLNVGGCIYTARRESLCRFKDSMLASMFSGRFPLKTDESGACVIDR 60
           MEGHKAEEEVLDVLRLNVGGCIYTARRESLCRFKDSMLASMFSGRFPLKTDESGACVIDR
Sbjct: 1   MEGHKAEEEVLDVLRLNVGGCIYTARRESLCRFKDSMLASMFSGRFPLKTDESGACVIDR 60

Query: 61  DGRLFKYLLDYLHGEVQIPTDEQTRIALQEEADYFGIPYPYSLSDHLANEMETYSLRSNI 120
           DGRLFKYLLDYLHGEVQIPTDEQTRIALQEEADYFGIPYPYSLSDHLANEMETYSLRSNI
Sbjct: 61  DGRLFKYLLDYLHGEVQIPTDEQTRIALQEEADYFGIPYPYSLSDHLANEMETYSLRSNI 120

Query: 121 ELKKALTDFCDSYGLVCNKPTVWVLHYLNTSGASCESRIIGVYATKTDGTDAIEKQLGGR 180
           ELKKALTDFCDSYGLVCNKPTVWVLHYLNTSGASCESRIIGVYATKTDGTDAIEKQLGGR
Sbjct: 121 ELKKALTDFCDSYGLVCNKPTVWVLHYLNTSGASCESRIIGVYATKTDGTDAIEKQLGGR 180

Query: 181 IHSKGIFKREAGNNVQYIWSYYSVAELKKMMDAFDAWEGKGVSYWRVPHELIECWTLEER 240
           IHSKGIFKREAGNNVQYIWSYYSVAELKKMMDAFDAWEGKGVSYWRVPHELIECWTLEER
Sbjct: 181 IHSKGIFKREAGNNVQYIWSYYSVAELKKMMDAFDAWEGKGVSYWRVPHELIECWTLEER 240

Query: 241 PLLGSLRHMAPIRKRRLITFNEADESVNYKTGPKPVRFLGPSTSTQIKVKNSASVTVSPA 300
           PLLGSLRHMAPIRKRRLITFNEADESVNYKTGPKPVRFLGPSTSTQIKVKNSASVTVSPA
Sbjct: 241 PLLGSLRHMAPIRKRRLITFNEADESVNYKTGPKPVRFLGPSTSTQIKVKNSASVTVSPA 300

Query: 301 SAIQTSAGATANRFQSGSRRKAAQRSAPSRATALVGTGAPGHPQASPGAASAENGGTHLP 360
           SAIQTSAGATANRFQSGSRRKAAQRSAPSRATALVGTGAPGHPQASPGAASAENGGTHLP
Sbjct: 301 SAIQTSAGATANRFQSGSRRKAAQRSAPSRATALVGTGAPGHPQASPGAASAENGGTHLP 360

Query: 361 PAKVLLSDKKPTPQRVIKLKRTPLCATAPCLPSPTATRQANSLKPLPGEAARALGVRTEN 420
           PAKVLLSDKKPTPQRVIKLKRTPLCATAPCLPSPTATRQANSLKPLPGEAARALGVRTEN
Sbjct: 361 PAKVLLSDKKPTPQRVIKLKRTPLCATAPCLPSPTATRQANSLKPLPGEAARALGVRTEN 420

Query: 421 GKNKGN 426
           GKNKGN
Sbjct: 421 GKNKGN 426


>gi|71143104 potassium channel tetramerisation domain containing
          21 [Homo sapiens]
          Length = 260

 Score = 82.0 bits (201), Expect = 9e-16
 Identities = 39/87 (44%), Positives = 56/87 (64%), Gaps = 1/87 (1%)

Query: 12 DVLRLNVGGCIYTARRESLCRFKDSMLASMFSGRFPLKTDESGACVIDRDGRLFKYLLDY 71
          D + LNVGG +YT    +L  F DSML +MFSG+ P K D  G C IDRDG++F+Y+L++
Sbjct: 3  DPITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTKRDSQGNCFIDRDGKVFRYILNF 62

Query: 72 LH-GEVQIPTDEQTRIALQEEADYFGI 97
          L    + +P D Q    L+ EAD++ +
Sbjct: 63 LRTSHLDLPEDFQEMGLLRREADFYQV 89


>gi|189571693 potassium channel tetramerisation domain containing 6
           [Homo sapiens]
          Length = 237

 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 46/134 (34%), Positives = 74/134 (55%), Gaps = 3/134 (2%)

Query: 12  DVLRLNVGGCIYTARRESLCRFKDSMLASMFSGRFPLKTDESGACVIDRDGRLFKYLLDY 71
           D + LNVGG +YT    +L R+ DSML +MF G FP   D  G   IDRDG LF+Y+L++
Sbjct: 12  DPVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDRDGPLFRYVLNF 71

Query: 72  LH-GEVQIPTDEQTRIALQEEADYFGI-PYPYSLSD-HLANEMETYSLRSNIELKKALTD 128
           L   E+ +P D +    L++EAD++ I P    L+D      M+T+     +   + L+ 
Sbjct: 72  LRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCLNDPKPLYPMDTFEEVVELSSTRKLSK 131

Query: 129 FCDSYGLVCNKPTV 142
           + +   ++  + T+
Sbjct: 132 YSNPVAVIITQLTI 145


>gi|189571691 potassium channel tetramerisation domain containing 6
           [Homo sapiens]
          Length = 237

 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 46/134 (34%), Positives = 74/134 (55%), Gaps = 3/134 (2%)

Query: 12  DVLRLNVGGCIYTARRESLCRFKDSMLASMFSGRFPLKTDESGACVIDRDGRLFKYLLDY 71
           D + LNVGG +YT    +L R+ DSML +MF G FP   D  G   IDRDG LF+Y+L++
Sbjct: 12  DPVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDRDGPLFRYVLNF 71

Query: 72  LH-GEVQIPTDEQTRIALQEEADYFGI-PYPYSLSD-HLANEMETYSLRSNIELKKALTD 128
           L   E+ +P D +    L++EAD++ I P    L+D      M+T+     +   + L+ 
Sbjct: 72  LRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCLNDPKPLYPMDTFEEVVELSSTRKLSK 131

Query: 129 FCDSYGLVCNKPTV 142
           + +   ++  + T+
Sbjct: 132 YSNPVAVIITQLTI 145


>gi|19923973 potassium channel tetramerisation domain containing 12
           [Homo sapiens]
          Length = 325

 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 38/90 (42%), Positives = 54/90 (60%), Gaps = 3/90 (3%)

Query: 12  DVLRLNVGGCIYTARRESLCRFKDSMLASMFSGRFP--LKTDESGACVIDRDGRLFKYLL 69
           D++ LNVGG +Y  RR ++    DS+L  MF+ + P  L  D  G   +DRDG LF+Y+L
Sbjct: 34  DIVELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQPQELARDSKGRFFLDRDGFLFRYIL 93

Query: 70  DYLHG-EVQIPTDEQTRIALQEEADYFGIP 98
           DYL   ++ +P     R  LQ EA+YF +P
Sbjct: 94  DYLRDLQLVLPDYFPERSRLQREAEYFELP 123


>gi|23308551 potassium channel tetramerisation domain containing 7
           [Homo sapiens]
          Length = 289

 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 37/90 (41%), Positives = 56/90 (62%), Gaps = 2/90 (2%)

Query: 8   EEVLDVLRLNVGGCIYTARRESLCRFKDSMLASMFSGRFPLKTDESGACVIDRDGRLFKY 67
           +E  +V+ LN+GG  +T R  +L  ++D+MLA+MFSGR  + TD  G   IDRDG  F  
Sbjct: 47  QEFPEVVPLNIGGAHFTTRLSTLRCYEDTMLAAMFSGRHYIPTDSEGRYFIDRDGTHFGD 106

Query: 68  LLDYLHGEVQIPTDEQTRIALQEEADYFGI 97
           +L++L     +P  E+ R A+ +EA Y+ I
Sbjct: 107 VLNFLRSG-DLPPRERVR-AVYKEAQYYAI 134


>gi|55926200 potassium channel tetramerisation domain containing 16
           [Homo sapiens]
          Length = 428

 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 44/136 (32%), Positives = 65/136 (47%), Gaps = 18/136 (13%)

Query: 2   EGHKAEEEVLDVLRLNVGGCIYTARRESLCRFKDSMLASMFSGRFP----LKTDESGACV 57
           +G        +V+ LNVGG +Y  R  +L     S+L  MFS +      L  D  G   
Sbjct: 15  QGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKGRFF 74

Query: 58  IDRDGRLFKYLLDYLHG-EVQIPTDEQTRIALQEEADYFGIPYPYSLSDHLANEMETYSL 116
           IDRDG LF+Y+LDYL   +V +P     +  L+ EA+YF +P             +   L
Sbjct: 75  IDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLP-------------DLVKL 121

Query: 117 RSNIELKKALTDFCDS 132
            +  E+K++  +FC S
Sbjct: 122 LTPDEIKQSPDEFCHS 137


>gi|10863937 tumor necrosis factor, alpha-induced protein 1 [Homo
           sapiens]
          Length = 316

 Score = 62.4 bits (150), Expect = 8e-10
 Identities = 46/130 (35%), Positives = 66/130 (50%), Gaps = 20/130 (15%)

Query: 14  LRLNVGGCIYTARRESLCRFKDSMLASMFSGRFPLKTDESGACVIDRDGRLFKYLLDYLH 73
           ++LNVGG +Y     +L R  D+ML +MFSGR  + TD+ G  +IDR G+ F  +L+YL 
Sbjct: 30  VQLNVGGSLYYTTVRALTRH-DTMLKAMFSGRMEVLTDKEGWILIDRCGKHFGTILNYLR 88

Query: 74  GE-VQIPTDEQTRIALQEEADYFGIPYPYSLSDHLANEMETYSLRSNIELKKALTDFCDS 132
            + + +P + Q    L  EA Y+       L   L N  ++           AL D  DS
Sbjct: 89  DDTITLPQNRQEIKELMAEAKYY-------LIQGLVNMCQS-----------ALQDKKDS 130

Query: 133 YGLVCNKPTV 142
           Y  VCN P +
Sbjct: 131 YQPVCNIPII 140


>gi|146198864 potassium channel tetramerisation domain containing 4
           [Homo sapiens]
          Length = 259

 Score = 62.4 bits (150), Expect = 8e-10
 Identities = 46/161 (28%), Positives = 82/161 (50%), Gaps = 16/161 (9%)

Query: 13  VLRLNVGGCIYTARRESLCRFKDSMLASMFSGRFPLKTDESGACVIDRDGRLFKYLLDYL 72
           ++ LNVGG +Y  ++++L ++ D+ L  + +G+     D  G   IDRDG LF+++L++L
Sbjct: 34  LMTLNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPFDADGHYFIDRDGLLFRHVLNFL 93

Query: 73  -HGEVQIPTDEQTRIALQEEADYFGIPYPYSLSDHLANEMETYSLRSNIELKKALTDFCD 131
            +GE+ +P   +    L +EA++F +     L++ + +  E   L         +TD  D
Sbjct: 94  RNGELLLPEGFRENQLLAQEAEFFQLK---GLAEEVKSRWEKEQLTPRETTFLEITDNHD 150

Query: 132 -SYGL--VCNKPTVWVLHYLNTSGASCESRIIGVYATKTDG 169
            S GL   CN P            +  +SRI+ V  ++ DG
Sbjct: 151 RSQGLRIFCNAPDFI---------SKIKSRIVLVSKSRLDG 182


>gi|13994353 potassium channel tetramerisation domain containing 10
           [Homo sapiens]
          Length = 313

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 51/192 (26%), Positives = 88/192 (45%), Gaps = 11/192 (5%)

Query: 14  LRLNVGGCIYTARRESLCRFKDSMLASMFSGRFPLKTDESGACVIDRDGRLFKYLLDYLH 73
           ++LNVGG +Y    ++L + +D+ML +MFSGR  + TD  G  +IDR G+ F  +L+YL 
Sbjct: 34  VKLNVGGALYYTTMQTLTK-QDTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTILNYLR 92

Query: 74  -GEVQIPTDEQTRIALQEEADYFGIPYPYSLSDHLANEMETYSLRSNIELKKALTDFCDS 132
            G V +P   +    L  EA Y+ +              +TY     + +   +T   + 
Sbjct: 93  DGAVPLPESRREIEELLAEAKYYLVQGLVEECQAALQNKDTYEPFCKVPV---ITSSKEE 149

Query: 133 YGLVC--NKPTVWVLHYLNTSGASCESRIIGVYATKTDGTDAIEKQLGGRIHSKGIFKRE 190
             L+   NKP V +L+  + +  S  S          +  D +  +  GR+    +F ++
Sbjct: 150 QKLIATSNKPAVKLLYNRSNNKYSYTSNSDDNMLKNIELFDKLSLRFNGRV----LFIKD 205

Query: 191 AGNNVQYIWSYY 202
              +    WS+Y
Sbjct: 206 VIGDEICCWSFY 217


>gi|38198663 potassium channel tetramerisation domain containing 8
           [Homo sapiens]
          Length = 473

 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 37/94 (39%), Positives = 49/94 (52%), Gaps = 10/94 (10%)

Query: 12  DVLRLNVGGCIYTARRESLCRFKDSMLASMFSGRFP---------LKTDESGACVIDRDG 62
           +V+ LNVGG +Y  +  +L    DS LASMFS   P         L  D      IDRDG
Sbjct: 44  EVVELNVGGQVYVTKHSTLLSVPDSTLASMFSPSSPRGGARRRGELPRDSRARFFIDRDG 103

Query: 63  RLFKYLLDYLHG-EVQIPTDEQTRIALQEEADYF 95
            LF+Y+LDYL   ++ +P     +  L  EA+YF
Sbjct: 104 FLFRYVLDYLRDKQLALPEHFPEKERLLREAEYF 137


>gi|39753959 potassium channel tetramerisation domain containing 9
           [Homo sapiens]
          Length = 389

 Score = 55.5 bits (132), Expect = 9e-08
 Identities = 43/100 (43%), Positives = 57/100 (57%), Gaps = 8/100 (8%)

Query: 12  DVLRLNVGGCIYTARRESLCRFK-DSMLASMFS--GRFPLKTDESGACVIDRDGRLFKYL 68
           D L LNVGG  +T  R +L   + DSMLA MF   G +  K D  GA +IDR    F+ +
Sbjct: 89  DWLTLNVGGRYFTTTRSTLVNKEPDSMLAHMFKDKGVWGNKQDHRGAFLIDRSPEYFEPI 148

Query: 69  LDYL-HGEVQIPTDEQTRIALQEEADYFGIPYPYSLSDHL 107
           L+YL HG++ I  D    + + EEA +FGI    SL +HL
Sbjct: 149 LNYLRHGQL-IVNDGINLLGVLEEARFFGID---SLIEHL 184


>gi|40807368 potassium channel regulator isoform 2 [Homo sapiens]
          Length = 229

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 31/85 (36%), Positives = 49/85 (57%), Gaps = 1/85 (1%)

Query: 12 DVLRLNVGGCIYTARRESLCRFKDSMLASMFSGRFPLKTDESGACVIDRDGRLFKYLLDY 71
          +++ LNVGG I+T R  ++ +F  S LA M  GR        G   +DRDG LF ++LD+
Sbjct: 5  ELVTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDRDGDLFSFILDF 64

Query: 72 LH-GEVQIPTDEQTRIALQEEADYF 95
          L   ++ +PT+    + LQ EA ++
Sbjct: 65 LRTHQLLLPTEFSDYLRLQREALFY 89


>gi|27734697 potassium channel regulator isoform 1 [Homo sapiens]
          Length = 272

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 31/85 (36%), Positives = 49/85 (57%), Gaps = 1/85 (1%)

Query: 12 DVLRLNVGGCIYTARRESLCRFKDSMLASMFSGRFPLKTDESGACVIDRDGRLFKYLLDY 71
          +++ LNVGG I+T R  ++ +F  S LA M  GR        G   +DRDG LF ++LD+
Sbjct: 5  ELVTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDRDGDLFSFILDF 64

Query: 72 LH-GEVQIPTDEQTRIALQEEADYF 95
          L   ++ +PT+    + LQ EA ++
Sbjct: 65 LRTHQLLLPTEFSDYLRLQREALFY 89


>gi|218505694 potassium channel tetramerisation domain containing 1
           isoform b [Homo sapiens]
          Length = 865

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 29/84 (34%), Positives = 50/84 (59%), Gaps = 2/84 (2%)

Query: 14  LRLNVGGCIYTARRESLCRFKDSMLASMFSGRFPLKTDE-SGACVIDRDGRLFKYLLDYL 72
           + ++VGG +YT+   +L ++ +S +  +F G  P+  D       IDRDG++F+Y+L++L
Sbjct: 640 VHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMFRYILNFL 699

Query: 73  H-GEVQIPTDEQTRIALQEEADYF 95
              ++ IP D +    L EEA YF
Sbjct: 700 RTSKLLIPDDFKDYTLLYEEAKYF 723


>gi|209969708 potassium channel tetramerisation domain containing 1
           isoform a [Homo sapiens]
          Length = 257

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 29/84 (34%), Positives = 50/84 (59%), Gaps = 2/84 (2%)

Query: 14  LRLNVGGCIYTARRESLCRFKDSMLASMFSGRFPLKTDE-SGACVIDRDGRLFKYLLDYL 72
           + ++VGG +YT+   +L ++ +S +  +F G  P+  D       IDRDG++F+Y+L++L
Sbjct: 32  VHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMFRYILNFL 91

Query: 73  H-GEVQIPTDEQTRIALQEEADYF 95
              ++ IP D +    L EEA YF
Sbjct: 92  RTSKLLIPDDFKDYTLLYEEAKYF 115


>gi|40217617 potassium channel tetramerisation domain containing 1
           isoform a [Homo sapiens]
          Length = 257

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 29/84 (34%), Positives = 50/84 (59%), Gaps = 2/84 (2%)

Query: 14  LRLNVGGCIYTARRESLCRFKDSMLASMFSGRFPLKTDE-SGACVIDRDGRLFKYLLDYL 72
           + ++VGG +YT+   +L ++ +S +  +F G  P+  D       IDRDG++F+Y+L++L
Sbjct: 32  VHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMFRYILNFL 91

Query: 73  H-GEVQIPTDEQTRIALQEEADYF 95
              ++ IP D +    L EEA YF
Sbjct: 92  RTSKLLIPDDFKDYTLLYEEAKYF 115


>gi|46255026 potassium channel tetramerisation domain containing 3
           [Homo sapiens]
          Length = 815

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 29/86 (33%), Positives = 51/86 (59%), Gaps = 1/86 (1%)

Query: 12  DVLRLNVGGCIYTARRESLCRFKDSMLASMFSGRFPLKTDESGACVIDRDGRLFKYLLDY 71
           ++++LNVGG  ++  R++L    DS  +S+ SGR     DE+GA  IDRD   F  +L++
Sbjct: 18  EIVQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGRISTLRDETGAIFIDRDPAAFAPILNF 77

Query: 72  LHGEVQIPTDEQTRIALQEEADYFGI 97
           L  + ++     +   L+ EA+++GI
Sbjct: 78  LRTK-ELDLRGVSINVLRHEAEFYGI 102


>gi|30578412 potassium channel tetramerisation domain containing 13
           [Homo sapiens]
          Length = 329

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 58/201 (28%), Positives = 93/201 (46%), Gaps = 28/201 (13%)

Query: 14  LRLNVGGCIYTARRESLCRFKDSMLASMFSGRFPLKTDESGACVIDRDGRLFKYLLDYLH 73
           ++LNVGG ++     +L   +D+ML +MFSGR  + TD  G  +IDR GR F  +L+YL 
Sbjct: 43  VKLNVGGSLHYTTLRTLTG-QDTMLKAMFSGRVEVLTDAGGWVLIDRSGRHFGTILNYLR 101

Query: 74  -GEVQIPTDEQTRIALQEEADYF---GIPYPYSLSDHLANEMETYSLRSNIELKKALTDF 129
            G V +P   +    L  EA Y+   G+     L+  L  + ET S    I +   +T  
Sbjct: 102 DGSVPLPESTRELGELLGEARYYLVQGLIEDCQLA--LQQKRETLSPLCLIPM---VTSP 156

Query: 130 CDSYGLVC--NKPTVWVLHYLNTSGASCESRIIGVYATKTDGTDAIEK------QLGGRI 181
            +   L+   +KP V +LH          +R    Y+  +   D + K      +L  R 
Sbjct: 157 REEQQLLASTSKPVVKLLH----------NRSNNKYSYTSTSDDNLLKNIELFDKLALRF 206

Query: 182 HSKGIFKREAGNNVQYIWSYY 202
           H + +F ++   +    WS+Y
Sbjct: 207 HGRLLFLKDVLGDEICCWSFY 227


>gi|169234778 potassium channel tetramerisation domain containing 17
           [Homo sapiens]
          Length = 297

 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 31/86 (36%), Positives = 51/86 (59%), Gaps = 3/86 (3%)

Query: 14  LRLNVGGCIYTARRESLCRFKDSMLASMFSG-RFPLKTDESGACVIDRDGRLFKYLLDYL 72
           +RLNVGG ++   R++LCR + S L+ +  G       DE+GA +IDRD   F  +L++L
Sbjct: 33  VRLNVGGTVFLTTRQTLCREQKSFLSRLCQGEELQSDRDETGAYLIDRDPTYFGPILNFL 92

Query: 73  -HGEVQIPTDEQTRIALQEEADYFGI 97
            HG++ +  D      + EEA+++ I
Sbjct: 93  RHGKLVLDKD-MAEEGVLEEAEFYNI 117


>gi|223005950 SH3KBP1 binding protein 1 [Homo sapiens]
          Length = 707

 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 30/86 (34%), Positives = 48/86 (55%), Gaps = 1/86 (1%)

Query: 12  DVLRLNVGGCIYTARRESLCRFKDSMLASMFSGRFPLKTDESGACVIDRDGRLFKYLLDY 71
           +V+ LNVGG  ++  R++L    DS  +S+ SGR     DE+GA  IDRD  +F  +L++
Sbjct: 19  EVIHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDETGAIFIDRDPTVFAPILNF 78

Query: 72  LHGEVQIPTDEQTRIALQEEADYFGI 97
           L  +   P       +L  EA ++G+
Sbjct: 79  LRTKELDPRGVHGS-SLLHEAQFYGL 103


>gi|194018443 potassium channel tetramerisation domain containing 15
           isoform 2 [Homo sapiens]
          Length = 283

 Score = 52.4 bits (124), Expect = 8e-07
 Identities = 28/84 (33%), Positives = 50/84 (59%), Gaps = 2/84 (2%)

Query: 14  LRLNVGGCIYTARRESLCRFKDSMLASMFSGRFPLKTDE-SGACVIDRDGRLFKYLLDYL 72
           + ++VGG +YT+   +L ++ DS ++ +F+G  P+  D       IDRDG +F+Y+L +L
Sbjct: 58  VHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVLSFL 117

Query: 73  H-GEVQIPTDEQTRIALQEEADYF 95
              ++ +P D +    L EEA Y+
Sbjct: 118 RTSKLLLPDDFKDFSLLYEEARYY 141


>gi|194018441 potassium channel tetramerisation domain containing 15
           isoform 2 [Homo sapiens]
          Length = 283

 Score = 52.4 bits (124), Expect = 8e-07
 Identities = 28/84 (33%), Positives = 50/84 (59%), Gaps = 2/84 (2%)

Query: 14  LRLNVGGCIYTARRESLCRFKDSMLASMFSGRFPLKTDE-SGACVIDRDGRLFKYLLDYL 72
           + ++VGG +YT+   +L ++ DS ++ +F+G  P+  D       IDRDG +F+Y+L +L
Sbjct: 58  VHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVLSFL 117

Query: 73  H-GEVQIPTDEQTRIALQEEADYF 95
              ++ +P D +    L EEA Y+
Sbjct: 118 RTSKLLLPDDFKDFSLLYEEARYY 141


>gi|194018439 potassium channel tetramerisation domain containing 15
           isoform 1 [Homo sapiens]
          Length = 234

 Score = 52.4 bits (124), Expect = 8e-07
 Identities = 28/84 (33%), Positives = 50/84 (59%), Gaps = 2/84 (2%)

Query: 14  LRLNVGGCIYTARRESLCRFKDSMLASMFSGRFPLKTDE-SGACVIDRDGRLFKYLLDYL 72
           + ++VGG +YT+   +L ++ DS ++ +F+G  P+  D       IDRDG +F+Y+L +L
Sbjct: 58  VHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVLSFL 117

Query: 73  H-GEVQIPTDEQTRIALQEEADYF 95
              ++ +P D +    L EEA Y+
Sbjct: 118 RTSKLLLPDDFKDFSLLYEEARYY 141


>gi|9506651 potassium channel tetramerisation domain containing 5
           [Homo sapiens]
          Length = 234

 Score = 48.9 bits (115), Expect = 9e-06
 Identities = 34/87 (39%), Positives = 49/87 (56%), Gaps = 4/87 (4%)

Query: 14  LRLNVGGCIYTARRESLCRFKDSMLASMFSGRFPLKTD--ESGACVIDRDGRLFKYLLDY 71
           +RLNVGG  +   R++LCR   S L  +      L +D  E+GA +IDRD   F  +L+Y
Sbjct: 46  VRLNVGGTYFLTTRQTLCRDPKSFLYRLCQADPDLDSDKDETGAYLIDRDPTYFGPVLNY 105

Query: 72  L-HGEVQIPTDEQTRIALQEEADYFGI 97
           L HG++ I  D      L EEA+++ I
Sbjct: 106 LRHGKLVINKDLAEEGVL-EEAEFYNI 131


>gi|142356950 potassium channel tetramerisation domain containing 14
           [Homo sapiens]
          Length = 255

 Score = 48.9 bits (115), Expect = 9e-06
 Identities = 32/85 (37%), Positives = 42/85 (49%), Gaps = 3/85 (3%)

Query: 13  VLRLNVGGCIYTARRESLCRFKDSMLASMFSGRFPLKTDESGACVIDRDGRLFKYLLDYL 72
           V+ LNVGG  +T    +L +F  S LA MFS      TD  G   IDR    F+ +LDYL
Sbjct: 34  VVELNVGGEFHTTTLGTLRKFPGSKLAEMFSSLAKASTDAEGRFFIDRPSTYFRPILDYL 93

Query: 73  HGEVQIPTDEQTRIALQEEADYFGI 97
               Q+PT     +    EA ++ I
Sbjct: 94  R-TGQVPTQHIPEV--YREAQFYEI 115


>gi|53829365 potassium channel tetramerisation domain containing 2
           [Homo sapiens]
          Length = 263

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 31/87 (35%), Positives = 44/87 (50%), Gaps = 3/87 (3%)

Query: 14  LRLNVGGCIYTARRESLCRFKDSMLASMFSGRFP---LKTDESGACVIDRDGRLFKYLLD 70
           +RLNVGG  +   R++L R   S L  +     P      DE+GA +IDRD   F  +L+
Sbjct: 74  VRLNVGGTYFVTTRQTLGREPKSFLCRLCCQEDPELDSDKDETGAYLIDRDPTYFGPILN 133

Query: 71  YLHGEVQIPTDEQTRIALQEEADYFGI 97
           YL     I T E     + EEA+++ I
Sbjct: 134 YLRHGKLIITKELAEEGVLEEAEFYNI 160


>gi|169184031 PREDICTED: similar to potassium channel
           tetramerisation domain containing 9 [Homo sapiens]
          Length = 261

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 39/100 (39%), Positives = 55/100 (55%), Gaps = 8/100 (8%)

Query: 12  DVLRLNVGGCIYTARRESLCRFK-DSMLASMFS--GRFPLKTDESGACVIDRDGRLFKYL 68
           D L L+VGG  +T    +L   + D MLA MF   G +  K D  GA +ID+    F+ +
Sbjct: 89  DWLTLHVGGQYFTTTWSTLVNKEPDIMLAHMFKDKGVWGNKQDHRGAFLIDQSPEYFEPI 148

Query: 69  LDYL-HGEVQIPTDEQTRIALQEEADYFGIPYPYSLSDHL 107
           L+YL HG++ I  D    + + EEA +FGI    SL +HL
Sbjct: 149 LNYLRHGQL-IVNDGIDLLGVLEEARFFGID---SLIEHL 184


>gi|169179790 PREDICTED: similar to potassium channel
           tetramerisation domain containing 9 [Homo sapiens]
          Length = 261

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 39/100 (39%), Positives = 55/100 (55%), Gaps = 8/100 (8%)

Query: 12  DVLRLNVGGCIYTARRESLCRFK-DSMLASMFS--GRFPLKTDESGACVIDRDGRLFKYL 68
           D L L+VGG  +T    +L   + D MLA MF   G +  K D  GA +ID+    F+ +
Sbjct: 89  DWLTLHVGGQYFTTTWSTLVNKEPDIMLAHMFKDKGVWGNKQDHRGAFLIDQSPEYFEPI 148

Query: 69  LDYL-HGEVQIPTDEQTRIALQEEADYFGIPYPYSLSDHL 107
           L+YL HG++ I  D    + + EEA +FGI    SL +HL
Sbjct: 149 LNYLRHGQL-IVNDGIDLLGVLEEARFFGID---SLIEHL 184


>gi|169180181 PREDICTED: similar to potassium channel
           tetramerisation domain containing 9 [Homo sapiens]
          Length = 261

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 39/100 (39%), Positives = 55/100 (55%), Gaps = 8/100 (8%)

Query: 12  DVLRLNVGGCIYTARRESLCRFK-DSMLASMFS--GRFPLKTDESGACVIDRDGRLFKYL 68
           D L L+VGG  +T    +L   + D MLA MF   G +  K D  GA +ID+    F+ +
Sbjct: 89  DWLTLHVGGQYFTTTWSTLVNKEPDIMLAHMFKDKGVWGNKQDHRGAFLIDQSPEYFEPI 148

Query: 69  LDYL-HGEVQIPTDEQTRIALQEEADYFGIPYPYSLSDHL 107
           L+YL HG++ I  D    + + EEA +FGI    SL +HL
Sbjct: 149 LNYLRHGQL-IVNDGIDLLGVLEEARFFGID---SLIEHL 184


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.132    0.392 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,564,324
Number of Sequences: 37866
Number of extensions: 862180
Number of successful extensions: 4110
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 47
Number of HSP's successfully gapped in prelim test: 135
Number of HSP's that attempted gapping in prelim test: 3920
Number of HSP's gapped (non-prelim): 311
length of query: 426
length of database: 18,247,518
effective HSP length: 105
effective length of query: 321
effective length of database: 14,271,588
effective search space: 4581179748
effective search space used: 4581179748
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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