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Search of human proteins with 4506029
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4506029 protein phosphatase 6, catalytic subunit isoform b
[Homo sapiens]
(305 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4506029 protein phosphatase 6, catalytic subunit isoform b [H... 646 0.0
gi|183603929 protein phosphatase 6, catalytic subunit isoform a ... 627 e-180
gi|183603931 protein phosphatase 6, catalytic subunit isoform c ... 585 e-167
gi|4506027 protein phosphatase 4, catalytic subunit [Homo sapiens] 409 e-114
gi|57222565 protein phosphatase 2, catalytic subunit, beta isofo... 376 e-104
gi|4758952 protein phosphatase 2, catalytic subunit, beta isofor... 376 e-104
gi|4506017 protein phosphatase 2, catalytic subunit, alpha isofo... 372 e-103
gi|56790945 protein phosphatase 1, catalytic subunit, alpha isof... 267 8e-72
gi|4506003 protein phosphatase 1, catalytic subunit, alpha isofo... 267 8e-72
gi|4506007 protein phosphatase 1, catalytic subunit, gamma isofo... 266 2e-71
gi|46249376 protein phosphatase 1, catalytic subunit, beta isofo... 258 4e-69
gi|4506005 protein phosphatase 1, catalytic subunit, beta isofor... 258 4e-69
gi|45827798 protein phosphatase 1, catalytic subunit, alpha isof... 250 1e-66
gi|194688147 protein phosphatase 3, catalytic subunit, alpha iso... 215 4e-56
gi|6715568 protein phosphatase 3, catalytic subunit, alpha isofo... 215 4e-56
gi|194688149 protein phosphatase 3, catalytic subunit, alpha iso... 212 3e-55
gi|215272354 protein phosphatase 3, catalytic subunit, beta isof... 211 8e-55
gi|215272352 protein phosphatase 3, catalytic subunit, beta isof... 211 8e-55
gi|11036640 protein phosphatase 3, catalytic subunit, beta isofo... 211 8e-55
gi|21361290 protein phosphatase 3, catalytic subunit, gamma [Hom... 206 2e-53
gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens] 206 3e-53
gi|239752750 PREDICTED: similar to protein phosphatase 2, cataly... 183 1e-46
gi|239747318 PREDICTED: similar to protein phosphatase 2, cataly... 181 5e-46
gi|239741140 PREDICTED: similar to protein phosphatase 2, cataly... 181 5e-46
gi|23312374 protein phosphatase with EF hand calcium-binding dom... 124 1e-28
gi|23312380 protein phosphatase with EF hand calcium-binding dom... 114 1e-25
gi|23312386 serine/threonine protein phosphatase with EF-hand mo... 104 1e-22
gi|23312378 protein phosphatase with EF hand calcium-binding dom... 86 3e-17
gi|112789548 lymphocyte-specific protein tyrosine kinase precurs... 30 2.7
gi|112789546 lymphocyte-specific protein tyrosine kinase precurs... 30 2.7
>gi|4506029 protein phosphatase 6, catalytic subunit isoform b [Homo
sapiens]
Length = 305
Score = 646 bits (1666), Expect = 0.0
Identities = 305/305 (100%), Positives = 305/305 (100%)
Query: 1 MAPLDLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYD 60
MAPLDLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYD
Sbjct: 1 MAPLDLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYD 60
Query: 61 LCELFRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQIT 120
LCELFRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQIT
Sbjct: 61 LCELFRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQIT 120
Query: 121 QVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIE 180
QVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIE
Sbjct: 121 QVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIE 180
Query: 181 RNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLV 240
RNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLV
Sbjct: 181 RNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLV 240
Query: 241 HEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTT 300
HEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTT
Sbjct: 241 HEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTT 300
Query: 301 TPYFL 305
TPYFL
Sbjct: 301 TPYFL 305
>gi|183603929 protein phosphatase 6, catalytic subunit isoform a
[Homo sapiens]
Length = 342
Score = 627 bits (1618), Expect = e-180
Identities = 305/342 (89%), Positives = 305/342 (89%), Gaps = 37/342 (10%)
Query: 1 MAPLDLDKYVEIARLCKYLPENDLK----------------------------------- 25
MAPLDLDKYVEIARLCKYLPENDLK
Sbjct: 1 MAPLDLDKYVEIARLCKYLPENDLKVSPICGLAPSGCGAPAGRPFLSPGPPPVFHFLRFL 60
Query: 26 --RLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIFMGDFV 83
RLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIFMGDFV
Sbjct: 61 KERLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIFMGDFV 120
Query: 84 DRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCT 143
DRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCT
Sbjct: 121 DRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCT 180
Query: 144 KVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVD 203
KVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVD
Sbjct: 181 KVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVD 240
Query: 204 TWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCY 263
TWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCY
Sbjct: 241 TWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCY 300
Query: 264 RCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTTTPYFL 305
RCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTTTPYFL
Sbjct: 301 RCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTTTPYFL 342
>gi|183603931 protein phosphatase 6, catalytic subunit isoform c
[Homo sapiens]
Length = 283
Score = 585 bits (1509), Expect = e-167
Identities = 283/305 (92%), Positives = 283/305 (92%), Gaps = 22/305 (7%)
Query: 1 MAPLDLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYD 60
MAPLDLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQ
Sbjct: 1 MAPLDLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQ--- 57
Query: 61 LCELFRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQIT 120
GDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQIT
Sbjct: 58 -------------------GDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQIT 98
Query: 121 QVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIE 180
QVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIE
Sbjct: 99 QVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIE 158
Query: 181 RNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLV 240
RNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLV
Sbjct: 159 RNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLV 218
Query: 241 HEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTT 300
HEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTT
Sbjct: 219 HEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTT 278
Query: 301 TPYFL 305
TPYFL
Sbjct: 279 TPYFL 283
>gi|4506027 protein phosphatase 4, catalytic subunit [Homo sapiens]
Length = 307
Score = 409 bits (1050), Expect = e-114
Identities = 187/302 (61%), Positives = 236/302 (78%), Gaps = 1/302 (0%)
Query: 5 DLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCEL 64
DLD+ +E R C+ + E+++K LC ++L+EESNVQ V +PVTVCGDIHGQFYDL EL
Sbjct: 6 DLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKEL 65
Query: 65 FRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYG 124
FR GG VP+TNY+FMGDFVDRG+YS+ETF LLALK ++PDRITL+RGNHESRQITQVYG
Sbjct: 66 FRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYG 125
Query: 125 FYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQE 184
FYDEC KYG+ WRYCT++FD L+++A+ID +I CVHGGLSP I+TLDQIRTI+R QE
Sbjct: 126 FYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQE 185
Query: 185 IPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGY 244
+PH G CDL+WSDPED W +SPRGAG+LFG+ V +F N++ +ICRAHQLV EGY
Sbjct: 186 VPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGY 245
Query: 245 KFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIP-PRTTTPY 303
K+ F+E ++TVWSAPNYCYRCGN+A+I+ + ++ +F A P R IP + Y
Sbjct: 246 KWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQETRGIPSKKPVADY 305
Query: 304 FL 305
FL
Sbjct: 306 FL 307
>gi|57222565 protein phosphatase 2, catalytic subunit, beta isoform
[Homo sapiens]
Length = 309
Score = 376 bits (966), Expect = e-104
Identities = 177/301 (58%), Positives = 217/301 (72%)
Query: 5 DLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCEL 64
+LD++VE CK L EN ++ LC+ ++L +ESNVQ V PVTVCGD+HGQF+DL EL
Sbjct: 9 ELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMEL 68
Query: 65 FRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYG 124
FR GG+ PDTNY+FMGD+VDRGYYS+ET T L+ALK ++P+RIT+LRGNHESRQITQVYG
Sbjct: 69 FRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYG 128
Query: 125 FYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQE 184
FYDEC KYGNAN W+Y T +FD L + AL+D QI C+HGGLSP I TLD IR ++R QE
Sbjct: 129 FYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQE 188
Query: 185 IPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGY 244
+PH+G CDL+WSDP+D W ISPRGAG+ FG ++ F H N L L+ RAHQLV EGY
Sbjct: 189 VPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGY 248
Query: 245 KFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTTTPYF 304
+ D +VT++SAPNYCYRCGN A+IM D F P R T YF
Sbjct: 249 NWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYF 308
Query: 305 L 305
L
Sbjct: 309 L 309
>gi|4758952 protein phosphatase 2, catalytic subunit, beta isoform
[Homo sapiens]
Length = 309
Score = 376 bits (966), Expect = e-104
Identities = 177/301 (58%), Positives = 217/301 (72%)
Query: 5 DLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCEL 64
+LD++VE CK L EN ++ LC+ ++L +ESNVQ V PVTVCGD+HGQF+DL EL
Sbjct: 9 ELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMEL 68
Query: 65 FRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYG 124
FR GG+ PDTNY+FMGD+VDRGYYS+ET T L+ALK ++P+RIT+LRGNHESRQITQVYG
Sbjct: 69 FRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYG 128
Query: 125 FYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQE 184
FYDEC KYGNAN W+Y T +FD L + AL+D QI C+HGGLSP I TLD IR ++R QE
Sbjct: 129 FYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQE 188
Query: 185 IPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGY 244
+PH+G CDL+WSDP+D W ISPRGAG+ FG ++ F H N L L+ RAHQLV EGY
Sbjct: 189 VPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGY 248
Query: 245 KFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTTTPYF 304
+ D +VT++SAPNYCYRCGN A+IM D F P R T YF
Sbjct: 249 NWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYF 308
Query: 305 L 305
L
Sbjct: 309 L 309
>gi|4506017 protein phosphatase 2, catalytic subunit, alpha isoform
[Homo sapiens]
Length = 309
Score = 372 bits (955), Expect = e-103
Identities = 175/301 (58%), Positives = 216/301 (71%)
Query: 5 DLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCEL 64
+LD+++E CK L E+ +K LC+ ++L +ESNVQ V PVTVCGD+HGQF+DL EL
Sbjct: 9 ELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMEL 68
Query: 65 FRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYG 124
FR GG+ PDTNY+FMGD+VDRGYYS+ET T L+ALK ++ +RIT+LRGNHESRQITQVYG
Sbjct: 69 FRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYG 128
Query: 125 FYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQE 184
FYDEC KYGNAN W+Y T +FD L + AL+D QI C+HGGLSP I TLD IR ++R QE
Sbjct: 129 FYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQE 188
Query: 185 IPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGY 244
+PH+G CDL+WSDP+D W ISPRGAG+ FG ++ F H N L L+ RAHQLV EGY
Sbjct: 189 VPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGY 248
Query: 245 KFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTTTPYF 304
+ D +VT++SAPNYCYRCGN A+IM D F P R T YF
Sbjct: 249 NWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYF 308
Query: 305 L 305
L
Sbjct: 309 L 309
>gi|56790945 protein phosphatase 1, catalytic subunit, alpha isoform
3 [Homo sapiens]
Length = 341
Score = 267 bits (683), Expect = 8e-72
Identities = 123/255 (48%), Positives = 176/255 (69%), Gaps = 2/255 (0%)
Query: 19 LPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIF 78
L EN+++ LC ++ L + + + P+ +CGDIHGQ+YDL LF GG P++NY+F
Sbjct: 41 LTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLF 100
Query: 79 MGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANA 138
+GD+VDRG SLET LLA K K+P+ LLRGNHE I ++YGFYDEC+ +Y N
Sbjct: 101 LGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRY-NIKL 159
Query: 139 WRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSD 198
W+ T F+ L +AA++DE+I C HGGLSPD+++++QIR I R ++P +G CDL+WSD
Sbjct: 160 WKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSD 219
Query: 199 PE-DVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWS 257
P+ DV W + RG + FGA+V +F+H ++L LICRAHQ+V +GY+F +LVT++S
Sbjct: 220 PDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFS 279
Query: 258 APNYCYRCGNIASIM 272
APNYC N ++M
Sbjct: 280 APNYCGEFDNAGAMM 294
>gi|4506003 protein phosphatase 1, catalytic subunit, alpha isoform
1 [Homo sapiens]
Length = 330
Score = 267 bits (683), Expect = 8e-72
Identities = 123/255 (48%), Positives = 176/255 (69%), Gaps = 2/255 (0%)
Query: 19 LPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIF 78
L EN+++ LC ++ L + + + P+ +CGDIHGQ+YDL LF GG P++NY+F
Sbjct: 30 LTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLF 89
Query: 79 MGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANA 138
+GD+VDRG SLET LLA K K+P+ LLRGNHE I ++YGFYDEC+ +Y N
Sbjct: 90 LGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRY-NIKL 148
Query: 139 WRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSD 198
W+ T F+ L +AA++DE+I C HGGLSPD+++++QIR I R ++P +G CDL+WSD
Sbjct: 149 WKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSD 208
Query: 199 PE-DVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWS 257
P+ DV W + RG + FGA+V +F+H ++L LICRAHQ+V +GY+F +LVT++S
Sbjct: 209 PDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFS 268
Query: 258 APNYCYRCGNIASIM 272
APNYC N ++M
Sbjct: 269 APNYCGEFDNAGAMM 283
>gi|4506007 protein phosphatase 1, catalytic subunit, gamma isoform
[Homo sapiens]
Length = 323
Score = 266 bits (679), Expect = 2e-71
Identities = 123/255 (48%), Positives = 176/255 (69%), Gaps = 2/255 (0%)
Query: 19 LPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIF 78
L EN+++ LC ++ L + + + P+ +CGDIHGQ+YDL LF GG P++NY+F
Sbjct: 30 LQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLF 89
Query: 79 MGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANA 138
+GD+VDRG SLET LLA K K+P+ LLRGNHE I ++YGFYDEC+ +Y N
Sbjct: 90 LGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRY-NIKL 148
Query: 139 WRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSD 198
W+ T F+ L +AA++DE+I C HGGLSPD+++++QIR I R ++P +G CDL+WSD
Sbjct: 149 WKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSD 208
Query: 199 PE-DVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWS 257
P+ DV W + RG + FGA+V +F+H ++L LICRAHQ+V +GY+F +LVT++S
Sbjct: 209 PDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFS 268
Query: 258 APNYCYRCGNIASIM 272
APNYC N ++M
Sbjct: 269 APNYCGEFDNAGAMM 283
>gi|46249376 protein phosphatase 1, catalytic subunit, beta isoform
1 [Homo sapiens]
Length = 327
Score = 258 bits (660), Expect = 4e-69
Identities = 125/296 (42%), Positives = 182/296 (61%), Gaps = 13/296 (4%)
Query: 19 LPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIF 78
+ E +++ LC ++ L + + + P+ +CGDIHGQ+ DL LF GG P+ NY+F
Sbjct: 29 MTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLF 88
Query: 79 MGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANA 138
+GD+VDRG SLET LLA K K+P+ LLRGNHE I ++YGFYDEC+ ++ N
Sbjct: 89 LGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRF-NIKL 147
Query: 139 WRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSD 198
W+ T F+ L +AA++DE+I C HGGLSPD+++++QIR I R ++P G CDL+WSD
Sbjct: 148 WKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSD 207
Query: 199 PE-DVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWS 257
P+ DV W + RG + FGA V ++F++ ++L LICRAHQ+V +GY+F +LVT++S
Sbjct: 208 PDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFS 267
Query: 258 APNYCYRCGN-----------IASIMVFKDVNTREPKLFRAVPDSERVIPPRTTTP 302
APNYC N + S + K + + + V PPRT P
Sbjct: 268 APNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAKYQYGGLNSGRPVTPPRTANP 323
>gi|4506005 protein phosphatase 1, catalytic subunit, beta isoform 1
[Homo sapiens]
Length = 327
Score = 258 bits (660), Expect = 4e-69
Identities = 125/296 (42%), Positives = 182/296 (61%), Gaps = 13/296 (4%)
Query: 19 LPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIF 78
+ E +++ LC ++ L + + + P+ +CGDIHGQ+ DL LF GG P+ NY+F
Sbjct: 29 MTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLF 88
Query: 79 MGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANA 138
+GD+VDRG SLET LLA K K+P+ LLRGNHE I ++YGFYDEC+ ++ N
Sbjct: 89 LGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRF-NIKL 147
Query: 139 WRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSD 198
W+ T F+ L +AA++DE+I C HGGLSPD+++++QIR I R ++P G CDL+WSD
Sbjct: 148 WKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSD 207
Query: 199 PE-DVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWS 257
P+ DV W + RG + FGA V ++F++ ++L LICRAHQ+V +GY+F +LVT++S
Sbjct: 208 PDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFS 267
Query: 258 APNYCYRCGN-----------IASIMVFKDVNTREPKLFRAVPDSERVIPPRTTTP 302
APNYC N + S + K + + + V PPRT P
Sbjct: 268 APNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAKYQYGGLNSGRPVTPPRTANP 323
>gi|45827798 protein phosphatase 1, catalytic subunit, alpha isoform
2 [Homo sapiens]
Length = 286
Score = 250 bits (639), Expect = 1e-66
Identities = 115/222 (51%), Positives = 158/222 (71%), Gaps = 2/222 (0%)
Query: 52 GDIHGQFYDLCELFRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLR 111
GDIHGQ+YDL LF GG P++NY+F+GD+VDRG SLET LLA K K+P+ LLR
Sbjct: 19 GDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLR 78
Query: 112 GNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIK 171
GNHE I ++YGFYDEC+ +Y N W+ T F+ L +AA++DE+I C HGGLSPD++
Sbjct: 79 GNHECASINRIYGFYDECKRRY-NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQ 137
Query: 172 TLDQIRTIERNQEIPHKGAFCDLVWSDPE-DVDTWAISPRGAGWLFGAKVTNEFVHINNL 230
+++QIR I R ++P +G CDL+WSDP+ DV W + RG + FGA+V +F+H ++L
Sbjct: 138 SMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDL 197
Query: 231 KLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRCGNIASIM 272
LICRAHQ+V +GY+F +LVT++SAPNYC N ++M
Sbjct: 198 DLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMM 239
>gi|194688147 protein phosphatase 3, catalytic subunit, alpha
isoform isoform 2 [Homo sapiens]
Length = 511
Score = 215 bits (547), Expect = 4e-56
Identities = 116/285 (40%), Positives = 165/285 (57%), Gaps = 16/285 (5%)
Query: 19 LPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIF 78
L E+ R+ +L +E N+ + PVTVCGDIHGQF+DL +LF GG +T Y+F
Sbjct: 56 LEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLF 115
Query: 79 MGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANA 138
+GD+VDRGY+S+E YL ALK +P + LLRGNHE R +T+ + F EC+ KY +
Sbjct: 116 LGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKY-SERV 174
Query: 139 WRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSD 198
+ C FD L +AAL+++Q LCVHGGLSP+I TLD IR ++R +E P G CD++WSD
Sbjct: 175 YDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSD 234
Query: 199 P-EDVDTWAI-------SPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDE 250
P ED + RG + + EF+ NNL I RAH+ GY+
Sbjct: 235 PLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKS 294
Query: 251 K------LVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVP 289
+ L+T++SAPNY N A+++ +++ N + F P
Sbjct: 295 QTTGFPSLITIFSAPNYLDVYNNKAAVLKYEN-NVMNIRQFNCSP 338
>gi|6715568 protein phosphatase 3, catalytic subunit, alpha isoform
isoform 1 [Homo sapiens]
Length = 521
Score = 215 bits (547), Expect = 4e-56
Identities = 116/285 (40%), Positives = 165/285 (57%), Gaps = 16/285 (5%)
Query: 19 LPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIF 78
L E+ R+ +L +E N+ + PVTVCGDIHGQF+DL +LF GG +T Y+F
Sbjct: 56 LEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLF 115
Query: 79 MGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANA 138
+GD+VDRGY+S+E YL ALK +P + LLRGNHE R +T+ + F EC+ KY +
Sbjct: 116 LGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKY-SERV 174
Query: 139 WRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSD 198
+ C FD L +AAL+++Q LCVHGGLSP+I TLD IR ++R +E P G CD++WSD
Sbjct: 175 YDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSD 234
Query: 199 P-EDVDTWAI-------SPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDE 250
P ED + RG + + EF+ NNL I RAH+ GY+
Sbjct: 235 PLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKS 294
Query: 251 K------LVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVP 289
+ L+T++SAPNY N A+++ +++ N + F P
Sbjct: 295 QTTGFPSLITIFSAPNYLDVYNNKAAVLKYEN-NVMNIRQFNCSP 338
>gi|194688149 protein phosphatase 3, catalytic subunit, alpha
isoform isoform 3 [Homo sapiens]
Length = 469
Score = 212 bits (540), Expect = 3e-55
Identities = 114/274 (41%), Positives = 159/274 (58%), Gaps = 15/274 (5%)
Query: 19 LPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIF 78
L E+ R+ +L +E N+ + PVTVCGDIHGQF+DL +LF GG +T Y+F
Sbjct: 56 LEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLF 115
Query: 79 MGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANA 138
+GD+VDRGY+S+E YL ALK +P + LLRGNHE R +T+ + F EC+ KY +
Sbjct: 116 LGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKY-SERV 174
Query: 139 WRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSD 198
+ C FD L +AAL+++Q LCVHGGLSP+I TLD IR ++R +E P G CD++WSD
Sbjct: 175 YDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSD 234
Query: 199 P-EDVDTWAI-------SPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDE 250
P ED + RG + + EF+ NNL I RAH+ GY+
Sbjct: 235 PLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKS 294
Query: 251 K------LVTVWSAPNYCYRCGNIASIMVFKDVN 278
+ L+T++SAPNY N + M+ +N
Sbjct: 295 QTTGFPSLITIFSAPNYLDVYNNKVTEMLVNVLN 328
>gi|215272354 protein phosphatase 3, catalytic subunit, beta isoform
c [Homo sapiens]
Length = 515
Score = 211 bits (536), Expect = 8e-55
Identities = 112/270 (41%), Positives = 158/270 (58%), Gaps = 16/270 (5%)
Query: 34 LLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIFMGDFVDRGYYSLETF 93
+L E + V P+TVCGDIHGQF+DL +LF GG +T Y+F+GD+VDRGY+S+E
Sbjct: 80 ILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECV 139
Query: 94 TYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAA 153
YL LK +P + LLRGNHE R +T+ + F EC+ KY + + C + FD L +AA
Sbjct: 140 LYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKY-SERVYEACMEAFDSLPLAA 198
Query: 154 LIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDP-EDVDTWAI----- 207
L+++Q LCVHGGLSP+I TLD IR ++R +E P G CDL+WSDP ED
Sbjct: 199 LLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFS 258
Query: 208 --SPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEK------LVTVWSAP 259
+ RG + + EF+ NNL I RAH+ GY+ + L+T++SAP
Sbjct: 259 HNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAP 318
Query: 260 NYCYRCGNIASIMVFKDVNTREPKLFRAVP 289
NY N A+++ +++ N + F P
Sbjct: 319 NYLDVYNNKAAVLKYEN-NVMNIRQFNCSP 347
>gi|215272352 protein phosphatase 3, catalytic subunit, beta isoform
a [Homo sapiens]
Length = 525
Score = 211 bits (536), Expect = 8e-55
Identities = 112/270 (41%), Positives = 158/270 (58%), Gaps = 16/270 (5%)
Query: 34 LLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIFMGDFVDRGYYSLETF 93
+L E + V P+TVCGDIHGQF+DL +LF GG +T Y+F+GD+VDRGY+S+E
Sbjct: 80 ILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECV 139
Query: 94 TYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAA 153
YL LK +P + LLRGNHE R +T+ + F EC+ KY + + C + FD L +AA
Sbjct: 140 LYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKY-SERVYEACMEAFDSLPLAA 198
Query: 154 LIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDP-EDVDTWAI----- 207
L+++Q LCVHGGLSP+I TLD IR ++R +E P G CDL+WSDP ED
Sbjct: 199 LLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFS 258
Query: 208 --SPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEK------LVTVWSAP 259
+ RG + + EF+ NNL I RAH+ GY+ + L+T++SAP
Sbjct: 259 HNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAP 318
Query: 260 NYCYRCGNIASIMVFKDVNTREPKLFRAVP 289
NY N A+++ +++ N + F P
Sbjct: 319 NYLDVYNNKAAVLKYEN-NVMNIRQFNCSP 347
>gi|11036640 protein phosphatase 3, catalytic subunit, beta isoform
b [Homo sapiens]
Length = 524
Score = 211 bits (536), Expect = 8e-55
Identities = 112/270 (41%), Positives = 158/270 (58%), Gaps = 16/270 (5%)
Query: 34 LLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIFMGDFVDRGYYSLETF 93
+L E + V P+TVCGDIHGQF+DL +LF GG +T Y+F+GD+VDRGY+S+E
Sbjct: 80 ILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECV 139
Query: 94 TYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAA 153
YL LK +P + LLRGNHE R +T+ + F EC+ KY + + C + FD L +AA
Sbjct: 140 LYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKY-SERVYEACMEAFDSLPLAA 198
Query: 154 LIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDP-EDVDTWAI----- 207
L+++Q LCVHGGLSP+I TLD IR ++R +E P G CDL+WSDP ED
Sbjct: 199 LLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFS 258
Query: 208 --SPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEK------LVTVWSAP 259
+ RG + + EF+ NNL I RAH+ GY+ + L+T++SAP
Sbjct: 259 HNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAP 318
Query: 260 NYCYRCGNIASIMVFKDVNTREPKLFRAVP 289
NY N A+++ +++ N + F P
Sbjct: 319 NYLDVYNNKAAVLKYEN-NVMNIRQFNCSP 347
>gi|21361290 protein phosphatase 3, catalytic subunit, gamma [Homo
sapiens]
Length = 512
Score = 206 bits (524), Expect = 2e-53
Identities = 110/270 (40%), Positives = 157/270 (58%), Gaps = 16/270 (5%)
Query: 34 LLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIFMGDFVDRGYYSLETF 93
+L +E + V P+TVCGDIHGQF+DL +LF GG +T Y+F+GD+VDRGY+S+E
Sbjct: 67 ILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGYFSIECV 126
Query: 94 TYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAA 153
YL +LK P + LLRGNHE R +T + F EC+ KY + + C + FD L +AA
Sbjct: 127 LYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKY-SEQVYDACMETFDCLPLAA 185
Query: 154 LIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDP-EDVDTWAI----- 207
L+++Q LCVHGG+SP+I +LD IR ++R E P G CDL+WSDP ED
Sbjct: 186 LLNQQFLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEKTLEHYT 245
Query: 208 --SPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEK------LVTVWSAP 259
+ RG + + EF+ NNL I RAH+ GY+ + L+T++SAP
Sbjct: 246 HNTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAP 305
Query: 260 NYCYRCGNIASIMVFKDVNTREPKLFRAVP 289
NY N A+++ +++ N + F P
Sbjct: 306 NYLDVYNNKAAVLKYEN-NVMNIRQFNCSP 334
>gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens]
Length = 499
Score = 206 bits (523), Expect = 3e-53
Identities = 113/245 (46%), Positives = 150/245 (61%), Gaps = 4/245 (1%)
Query: 48 VTVCGDIHGQFYDLCELFRTGGQVPDTN-YIFMGDFVDRGYYSLETFTYLLALKAKWPDR 106
+TVCGD HGQFYDL +F G +TN YIF GDFVDRG +S+E L K +PD
Sbjct: 237 ITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDH 296
Query: 107 ITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGL 166
LLRGNHE+ + Q+YGF E + KY A + ++VF+ L +A I+ ++L +HGGL
Sbjct: 297 FHLLRGNHETDNMNQIYGFEGEVKAKY-TAQMYELFSEVFEWLPLAQCINGKVLIMHGGL 355
Query: 167 -SPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFV 225
S D TLD IR IERN++ P G CDL+WSDP+ + +IS RG FG VT F+
Sbjct: 356 FSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFL 415
Query: 226 HINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTR-EPKL 284
NNL I R+H++ EGY+ + VTV+SAPNYC + GN AS + + + R +
Sbjct: 416 EENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQ 475
Query: 285 FRAVP 289
F AVP
Sbjct: 476 FTAVP 480
>gi|239752750 PREDICTED: similar to protein phosphatase 2, catalytic
subunit, alpha [Homo sapiens]
Length = 384
Score = 183 bits (465), Expect = 1e-46
Identities = 103/251 (41%), Positives = 134/251 (53%), Gaps = 55/251 (21%)
Query: 19 LPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIF 78
L +K LC ++L EESN Q V PVTV GD HGQ
Sbjct: 172 LGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHGQ--------------------- 210
Query: 79 MGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANA 138
GD++DRGYYS+E LLA+K + + +T+L NHESRQITQVY Y+EC K+GNAN
Sbjct: 211 -GDYIDRGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGNANG 269
Query: 139 WRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSD 198
D Q+ C+HGGLSP + TL IRT+ Q+IPH+G DL++SD
Sbjct: 270 -----------------DGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSD 312
Query: 199 PEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSA 258
P+D DT F H + L+L+ RAHQLV G+ + D +V ++S
Sbjct: 313 PDDHDT----------------PETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFST 356
Query: 259 PNYCYRCGNIA 269
PNYCY CG +A
Sbjct: 357 PNYCYHCGGMA 367
>gi|239747318 PREDICTED: similar to protein phosphatase 2, catalytic
subunit, alpha [Homo sapiens]
Length = 254
Score = 181 bits (460), Expect = 5e-46
Identities = 102/248 (41%), Positives = 132/248 (53%), Gaps = 55/248 (22%)
Query: 19 LPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIF 78
L +K LC ++L EESN Q V PVTV GD HGQ
Sbjct: 51 LGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHGQ--------------------- 89
Query: 79 MGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANA 138
GD++DRGYYS+E LLA+K + + +T+L NHESRQITQVY Y+EC K+GNAN
Sbjct: 90 -GDYIDRGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGNANG 148
Query: 139 WRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSD 198
D Q+ C+HGGLSP + TL IRT+ Q+IPH+G DL++SD
Sbjct: 149 -----------------DGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSD 191
Query: 199 PEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSA 258
P+D DT F H + L+L+ RAHQLV G+ + D +V ++S
Sbjct: 192 PDDHDT----------------PETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFST 235
Query: 259 PNYCYRCG 266
PNYCY CG
Sbjct: 236 PNYCYHCG 243
>gi|239741140 PREDICTED: similar to protein phosphatase 2, catalytic
subunit, alpha [Homo sapiens]
Length = 254
Score = 181 bits (460), Expect = 5e-46
Identities = 102/248 (41%), Positives = 132/248 (53%), Gaps = 55/248 (22%)
Query: 19 LPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIF 78
L +K LC ++L EESN Q V PVTV GD HGQ
Sbjct: 51 LGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHGQ--------------------- 89
Query: 79 MGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANA 138
GD++DRGYYS+E LLA+K + + +T+L NHESRQITQVY Y+EC K+GNAN
Sbjct: 90 -GDYIDRGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGNANG 148
Query: 139 WRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSD 198
D Q+ C+HGGLSP + TL IRT+ Q+IPH+G DL++SD
Sbjct: 149 -----------------DGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSD 191
Query: 199 PEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSA 258
P+D DT F H + L+L+ RAHQLV G+ + D +V ++S
Sbjct: 192 PDDHDT----------------PETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFST 235
Query: 259 PNYCYRCG 266
PNYCY CG
Sbjct: 236 PNYCYHCG 243
>gi|23312374 protein phosphatase with EF hand calcium-binding domain
1 isoform 1b [Homo sapiens]
Length = 625
Score = 124 bits (311), Expect = 1e-28
Identities = 79/237 (33%), Positives = 121/237 (51%), Gaps = 21/237 (8%)
Query: 45 STPVTVCGDIHGQFYDLCELFRTGGQVPDTN-YIFMGDFVDRGYYSLETFTYLLALKAKW 103
S VT+CGD+HG+ DL +F G + N Y+F GDFVDRG S+E L +
Sbjct: 164 SKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVY 223
Query: 104 PDRITLLRGNHESRQITQVYGFYDECQTKYG--NANAWRYCTKVFDMLTVAALIDEQILC 161
P+ + L RGNHE + YGF E KY + + + L + ++D +IL
Sbjct: 224 PNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILV 283
Query: 162 VHGGLSPDIKTLDQIRTIERNQE----IP------------HKGAFCDLVWSDPEDVD-T 204
+HGG+S + L+ + +ERN+ IP D++WSDP +
Sbjct: 284 IHGGIS-ETTDLNLLHRVERNKMKSVLIPPTETNRDHDTDSKHNKIIDILWSDPRGKNGC 342
Query: 205 WAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNY 261
+ + RG G FG VT++ ++ LK++ R+H+ EGY+ D K+VT++SA NY
Sbjct: 343 FPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNY 399
>gi|23312380 protein phosphatase with EF hand calcium-binding domain
1 isoform 1 [Homo sapiens]
Length = 653
Score = 114 bits (285), Expect = 1e-25
Identities = 79/265 (29%), Positives = 122/265 (46%), Gaps = 49/265 (18%)
Query: 45 STPVTVCGDIHGQFYDLCELFRTGGQVPDTN-YIFMGDFVDRGYYSLETFTYLLALKAKW 103
S VT+CGD+HG+ DL +F G + N Y+F GDFVDRG S+E L +
Sbjct: 164 SKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVY 223
Query: 104 PDRITLLRGNHESRQITQVYGFYDECQTKY--GNANAWRYCTKVFDMLTVAALIDEQILC 161
P+ + L RGNHE + YGF E KY + + + L + ++D +IL
Sbjct: 224 PNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILV 283
Query: 162 VHGGLSPDIKTLDQIRTIERNQ--------------------------------EIPHKG 189
+HGG+S + L+ + +ERN+ I G
Sbjct: 284 IHGGIS-ETTDLNLLHRVERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNG 342
Query: 190 A------------FCDLVWSDPEDVD-TWAISPRGAGWLFGAKVTNEFVHINNLKLICRA 236
+ D++WSDP + + + RG G FG VT++ ++ LK++ R+
Sbjct: 343 SPTEHLTEHEWEQIIDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRS 402
Query: 237 HQLVHEGYKFMFDEKLVTVWSAPNY 261
H+ EGY+ D K+VT++SA NY
Sbjct: 403 HECKPEGYEICHDGKVVTIFSASNY 427
>gi|23312386 serine/threonine protein phosphatase with EF-hand
motifs 2 [Homo sapiens]
Length = 753
Score = 104 bits (259), Expect = 1e-22
Identities = 68/168 (40%), Positives = 89/168 (52%), Gaps = 15/168 (8%)
Query: 30 YVCDLLLEES-------NVQPVST----PVTVCGDIHGQFYDLCELF-RTGGQVPDTNYI 77
YV +LL E N+ VST +TVCGD+HGQ DL +F + G P+ +Y+
Sbjct: 145 YVLNLLYETKKHLVQLPNINRVSTCYSEEITVCGDLHGQLDDLIFIFYKNGLPSPERSYV 204
Query: 78 FMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKY--GN 135
F GDFVDRG S+E L A +P L RGNHE + YGF E KY
Sbjct: 205 FNGDFVDRGKDSVEILMILFAFMLVYPKEFHLNRGNHEDHMVNLRYGFTKEVMNKYKVHG 264
Query: 136 ANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQ 183
R VF L +A LIDE++L +HGG+S DI L+ + IER++
Sbjct: 265 KEILRTLQDVFCWLPLATLIDEKVLILHGGVS-DITDLELLDKIERSK 311
Score = 54.3 bits (129), Expect = 1e-07
Identities = 28/76 (36%), Positives = 46/76 (60%), Gaps = 2/76 (2%)
Query: 193 DLVWSDPEDVDTW-AISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEK 251
D++WSDP + A + RG G FG VT + + N++ + R+H+ EGY+F + K
Sbjct: 443 DILWSDPMAQEGCKANTIRGGGCYFGPDVTQQLLQKYNMQFLIRSHECKPEGYEFCHNRK 502
Query: 252 LVTVWSAPNYCYRCGN 267
++T++SA NY Y G+
Sbjct: 503 VLTIFSASNY-YEVGS 517
>gi|23312378 protein phosphatase with EF hand calcium-binding domain
1 isoform 3 [Homo sapiens]
Length = 591
Score = 86.3 bits (212), Expect = 3e-17
Identities = 50/142 (35%), Positives = 75/142 (52%), Gaps = 4/142 (2%)
Query: 45 STPVTVCGDIHGQFYDLCELFRTGGQVPDTN-YIFMGDFVDRGYYSLETFTYLLALKAKW 103
S VT+CGD+HG+ DL +F G + N Y+F GDFVDRG S+E L +
Sbjct: 164 SKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVY 223
Query: 104 PDRITLLRGNHESRQITQVYGFYDECQTKY--GNANAWRYCTKVFDMLTVAALIDEQILC 161
P+ + L RGNHE + YGF E KY + + + L + ++D +IL
Sbjct: 224 PNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILV 283
Query: 162 VHGGLSPDIKTLDQIRTIERNQ 183
+HGG+S + L+ + +ERN+
Sbjct: 284 IHGGIS-ETTDLNLLHRVERNK 304
>gi|112789548 lymphocyte-specific protein tyrosine kinase precursor
[Homo sapiens]
Length = 509
Score = 30.0 bits (66), Expect = 2.7
Identities = 18/67 (26%), Positives = 28/67 (41%)
Query: 160 LCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAK 219
+ V LS I R IE N+ +GA + W+ PE ++ + + W FG
Sbjct: 370 ILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGIL 429
Query: 220 VTNEFVH 226
+T H
Sbjct: 430 LTEIVTH 436
>gi|112789546 lymphocyte-specific protein tyrosine kinase precursor
[Homo sapiens]
Length = 509
Score = 30.0 bits (66), Expect = 2.7
Identities = 18/67 (26%), Positives = 28/67 (41%)
Query: 160 LCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAK 219
+ V LS I R IE N+ +GA + W+ PE ++ + + W FG
Sbjct: 370 ILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGIL 429
Query: 220 VTNEFVH 226
+T H
Sbjct: 430 LTEIVTH 436
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.141 0.457
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,671,817
Number of Sequences: 37866
Number of extensions: 564068
Number of successful extensions: 1337
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1248
Number of HSP's gapped (non-prelim): 38
length of query: 305
length of database: 18,247,518
effective HSP length: 102
effective length of query: 203
effective length of database: 14,385,186
effective search space: 2920192758
effective search space used: 2920192758
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.