BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|4506027 protein phosphatase 4, catalytic subunit [Homo sapiens] (307 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|4506027 protein phosphatase 4, catalytic subunit [Homo sapiens] 636 0.0 gi|57222565 protein phosphatase 2, catalytic subunit, beta isofo... 439 e-123 gi|4758952 protein phosphatase 2, catalytic subunit, beta isofor... 439 e-123 gi|4506017 protein phosphatase 2, catalytic subunit, alpha isofo... 438 e-123 gi|4506029 protein phosphatase 6, catalytic subunit isoform b [H... 409 e-114 gi|183603929 protein phosphatase 6, catalytic subunit isoform a ... 390 e-109 gi|183603931 protein phosphatase 6, catalytic subunit isoform c ... 359 2e-99 gi|4506007 protein phosphatase 1, catalytic subunit, gamma isofo... 295 4e-80 gi|56790945 protein phosphatase 1, catalytic subunit, alpha isof... 293 1e-79 gi|4506003 protein phosphatase 1, catalytic subunit, alpha isofo... 293 1e-79 gi|46249376 protein phosphatase 1, catalytic subunit, beta isofo... 288 3e-78 gi|4506005 protein phosphatase 1, catalytic subunit, beta isofor... 288 3e-78 gi|45827798 protein phosphatase 1, catalytic subunit, alpha isof... 266 2e-71 gi|194688147 protein phosphatase 3, catalytic subunit, alpha iso... 224 6e-59 gi|6715568 protein phosphatase 3, catalytic subunit, alpha isofo... 224 6e-59 gi|215272354 protein phosphatase 3, catalytic subunit, beta isof... 224 7e-59 gi|215272352 protein phosphatase 3, catalytic subunit, beta isof... 224 7e-59 gi|11036640 protein phosphatase 3, catalytic subunit, beta isofo... 224 7e-59 gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens] 221 8e-58 gi|194688149 protein phosphatase 3, catalytic subunit, alpha iso... 219 2e-57 gi|21361290 protein phosphatase 3, catalytic subunit, gamma [Hom... 215 5e-56 gi|239752750 PREDICTED: similar to protein phosphatase 2, cataly... 208 4e-54 gi|239747318 PREDICTED: similar to protein phosphatase 2, cataly... 205 5e-53 gi|239741140 PREDICTED: similar to protein phosphatase 2, cataly... 205 5e-53 gi|23312374 protein phosphatase with EF hand calcium-binding dom... 133 2e-31 gi|23312380 protein phosphatase with EF hand calcium-binding dom... 122 5e-28 gi|23312386 serine/threonine protein phosphatase with EF-hand mo... 107 1e-23 gi|23312378 protein phosphatase with EF hand calcium-binding dom... 99 6e-21 gi|8393264 delta-like 3 protein isoform 1 precursor [Homo sapiens] 30 3.5 gi|38679914 mitochondrial distribution and morphology 20 [Homo s... 29 4.6 >gi|4506027 protein phosphatase 4, catalytic subunit [Homo sapiens] Length = 307 Score = 636 bits (1640), Expect = 0.0 Identities = 307/307 (100%), Positives = 307/307 (100%) Query: 1 MAEISDLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFY 60 MAEISDLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFY Sbjct: 1 MAEISDLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFY 60 Query: 61 DLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQI 120 DLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQI Sbjct: 61 DLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQI 120 Query: 121 TQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTI 180 TQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTI Sbjct: 121 TQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTI 180 Query: 181 DRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQL 240 DRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQL Sbjct: 181 DRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQL 240 Query: 241 VMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQETRGIPSKK 300 VMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQETRGIPSKK Sbjct: 241 VMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQETRGIPSKK 300 Query: 301 PVADYFL 307 PVADYFL Sbjct: 301 PVADYFL 307 >gi|57222565 protein phosphatase 2, catalytic subunit, beta isoform [Homo sapiens] Length = 309 Score = 439 bits (1128), Expect = e-123 Identities = 200/303 (66%), Positives = 248/303 (81%), Gaps = 3/303 (0%) Query: 6 DLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKEL 65 +LD+ +EQL C+ + E++V+ LC KA+EIL +ESNVQ V PVTVCGD+HGQF+DL EL Sbjct: 9 ELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMEL 68 Query: 66 FRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYG 125 FR+GG P+TNYLFMGD+VDRG+YSVET LL+ALKVRYP+RIT++RGNHESRQITQVYG Sbjct: 69 FRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYG 128 Query: 126 FYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQE 185 FYDECLRKYG+ VW+Y T++FDYL L+A++DG+IFC+HGGLSPSI TLD IR +DR QE Sbjct: 129 FYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQE 188 Query: 186 VPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGY 245 VPH+GPMCDLLWSDP+D GWG+SPRGAGY FG D+ FN AN + ++ RAHQLVMEGY Sbjct: 189 VPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGY 248 Query: 246 KWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQETRGIPS-KKPVAD 304 W + V+T++SAPNYCYRCGN AAI+ELD+ L+ F+ F+ AP+ RG P + D Sbjct: 249 NWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPR--RGEPHVTRRTPD 306 Query: 305 YFL 307 YFL Sbjct: 307 YFL 309 >gi|4758952 protein phosphatase 2, catalytic subunit, beta isoform [Homo sapiens] Length = 309 Score = 439 bits (1128), Expect = e-123 Identities = 200/303 (66%), Positives = 248/303 (81%), Gaps = 3/303 (0%) Query: 6 DLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKEL 65 +LD+ +EQL C+ + E++V+ LC KA+EIL +ESNVQ V PVTVCGD+HGQF+DL EL Sbjct: 9 ELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMEL 68 Query: 66 FRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYG 125 FR+GG P+TNYLFMGD+VDRG+YSVET LL+ALKVRYP+RIT++RGNHESRQITQVYG Sbjct: 69 FRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYG 128 Query: 126 FYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQE 185 FYDECLRKYG+ VW+Y T++FDYL L+A++DG+IFC+HGGLSPSI TLD IR +DR QE Sbjct: 129 FYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQE 188 Query: 186 VPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGY 245 VPH+GPMCDLLWSDP+D GWG+SPRGAGY FG D+ FN AN + ++ RAHQLVMEGY Sbjct: 189 VPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGY 248 Query: 246 KWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQETRGIPS-KKPVAD 304 W + V+T++SAPNYCYRCGN AAI+ELD+ L+ F+ F+ AP+ RG P + D Sbjct: 249 NWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPR--RGEPHVTRRTPD 306 Query: 305 YFL 307 YFL Sbjct: 307 YFL 309 >gi|4506017 protein phosphatase 2, catalytic subunit, alpha isoform [Homo sapiens] Length = 309 Score = 438 bits (1127), Expect = e-123 Identities = 202/303 (66%), Positives = 248/303 (81%), Gaps = 3/303 (0%) Query: 6 DLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKEL 65 +LD+ IEQL C+ + ES+VK+LC KA+EIL +ESNVQ V PVTVCGD+HGQF+DL EL Sbjct: 9 ELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMEL 68 Query: 66 FRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYG 125 FR+GG P+TNYLFMGD+VDRG+YSVET LL+ALKVRY +RIT++RGNHESRQITQVYG Sbjct: 69 FRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYG 128 Query: 126 FYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQE 185 FYDECLRKYG+ VW+Y T++FDYL L+A++DG+IFC+HGGLSPSI TLD IR +DR QE Sbjct: 129 FYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQE 188 Query: 186 VPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGY 245 VPH+GPMCDLLWSDP+D GWG+SPRGAGY FG D+ FN AN + ++ RAHQLVMEGY Sbjct: 189 VPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGY 248 Query: 246 KWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQETRGIPS-KKPVAD 304 W + V+T++SAPNYCYRCGN AAI+ELD+ L+ F+ F+ AP+ RG P + D Sbjct: 249 NWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPR--RGEPHVTRRTPD 306 Query: 305 YFL 307 YFL Sbjct: 307 YFL 309 >gi|4506029 protein phosphatase 6, catalytic subunit isoform b [Homo sapiens] Length = 305 Score = 409 bits (1050), Expect = e-114 Identities = 187/302 (61%), Positives = 236/302 (78%), Gaps = 1/302 (0%) Query: 6 DLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKEL 65 DLD+ +E R C+ + E+++K LC ++L+EESNVQ V +PVTVCGDIHGQFYDL EL Sbjct: 5 DLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCEL 64 Query: 66 FRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYG 125 FR GG VP+TNY+FMGDFVDRG+YS+ETF LLALK ++PDRITL+RGNHESRQITQVYG Sbjct: 65 FRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYG 124 Query: 126 FYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQE 185 FYDEC KYG+ WRYCT++FD L+++A+ID +I CVHGGLSP I+TLDQIRTI+R QE Sbjct: 125 FYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQE 184 Query: 186 VPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGY 245 +PH G CDL+WSDPED W +SPRGAG+LFG+ V +F N++ +ICRAHQLV EGY Sbjct: 185 IPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGY 244 Query: 246 KWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQETRGIPSKKPVADY 305 K+ F+E ++TVWSAPNYCYRCGN+A+I+ + ++ +F A P R IP + Y Sbjct: 245 KFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIP-PRTTTPY 303 Query: 306 FL 307 FL Sbjct: 304 FL 305 >gi|183603929 protein phosphatase 6, catalytic subunit isoform a [Homo sapiens] Length = 342 Score = 390 bits (1003), Expect = e-109 Identities = 179/280 (63%), Positives = 221/280 (78%), Gaps = 1/280 (0%) Query: 28 LCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRG 87 LC ++L+EESNVQ V +PVTVCGDIHGQFYDL ELFR GG VP+TNY+FMGDFVDRG Sbjct: 64 LCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIFMGDFVDRG 123 Query: 88 FYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWRYCTEIF 147 +YS+ETF LLALK ++PDRITL+RGNHESRQITQVYGFYDEC KYG+ WRYCT++F Sbjct: 124 YYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVF 183 Query: 148 DYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWG 207 D L+++A+ID +I CVHGGLSP I+TLDQIRTI+R QE+PH G CDL+WSDPED W Sbjct: 184 DMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWA 243 Query: 208 VSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCG 267 +SPRGAG+LFG+ V +F N++ +ICRAHQLV EGYK+ F+E ++TVWSAPNYCYRCG Sbjct: 244 ISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRCG 303 Query: 268 NVAAILELDEHLQKDFIIFEAAPQETRGIPSKKPVADYFL 307 N+A+I+ + ++ +F A P R IP + YFL Sbjct: 304 NIASIMVFKDVNTREPKLFRAVPDSERVIP-PRTTTPYFL 342 >gi|183603931 protein phosphatase 6, catalytic subunit isoform c [Homo sapiens] Length = 283 Score = 359 bits (921), Expect = 2e-99 Identities = 170/302 (56%), Positives = 217/302 (71%), Gaps = 23/302 (7%) Query: 6 DLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKEL 65 DLD+ +E R C+ + E+++K LC ++L+EESNVQ V +PVTVCGDIHGQ Sbjct: 5 DLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQ------- 57 Query: 66 FRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYG 125 GDFVDRG+YS+ETF LLALK ++PDRITL+RGNHESRQITQVYG Sbjct: 58 ---------------GDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYG 102 Query: 126 FYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQE 185 FYDEC KYG+ WRYCT++FD L+++A+ID +I CVHGGLSP I+TLDQIRTI+R QE Sbjct: 103 FYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQE 162 Query: 186 VPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGY 245 +PH G CDL+WSDPED W +SPRGAG+LFG+ V +F N++ +ICRAHQLV EGY Sbjct: 163 IPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGY 222 Query: 246 KWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQETRGIPSKKPVADY 305 K+ F+E ++TVWSAPNYCYRCGN+A+I+ + ++ +F A P R IP + Y Sbjct: 223 KFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIP-PRTTTPY 281 Query: 306 FL 307 FL Sbjct: 282 FL 283 >gi|4506007 protein phosphatase 1, catalytic subunit, gamma isoform [Homo sapiens] Length = 323 Score = 295 bits (754), Expect = 4e-80 Identities = 136/282 (48%), Positives = 199/282 (70%), Gaps = 6/282 (2%) Query: 20 IKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLF 79 ++E+E++ LC K+REI + + + +++P+ +CGDIHGQ+YDL LF GG PE+NYLF Sbjct: 30 LQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLF 89 Query: 80 MGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTV 139 +GD+VDRG S+ET LLLA K++YP+ L+RGNHE I ++YGFYDEC R+Y ++ + Sbjct: 90 LGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRY-NIKL 148 Query: 140 WRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSD 199 W+ T+ F+ L ++AI+D KIFC HGGLSP +Q+++QIR I R +VP G +CDLLWSD Sbjct: 149 WKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSD 208 Query: 200 PE-DTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWS 258 P+ D GWG + RG + FG++VVA+F +D+D+ICRAHQ+V +GY++ ++T++S Sbjct: 209 PDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFS 268 Query: 259 APNYCYRCGNVAAILELDEHLQKDFIIFEAA----PQETRGI 296 APNYC N A++ +DE L F I + A P TR + Sbjct: 269 APNYCGEFDNAGAMMSVDETLMCSFQILKPAEKKKPNATRPV 310 >gi|56790945 protein phosphatase 1, catalytic subunit, alpha isoform 3 [Homo sapiens] Length = 341 Score = 293 bits (750), Expect = 1e-79 Identities = 133/271 (49%), Positives = 194/271 (71%), Gaps = 2/271 (0%) Query: 20 IKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLF 79 + E+E++ LC K+REI + + + +++P+ +CGDIHGQ+YDL LF GG PE+NYLF Sbjct: 41 LTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLF 100 Query: 80 MGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTV 139 +GD+VDRG S+ET LLLA K++YP+ L+RGNHE I ++YGFYDEC R+Y ++ + Sbjct: 101 LGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRY-NIKL 159 Query: 140 WRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSD 199 W+ T+ F+ L ++AI+D KIFC HGGLSP +Q+++QIR I R +VP G +CDLLWSD Sbjct: 160 WKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSD 219 Query: 200 PE-DTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWS 258 P+ D GWG + RG + FG++VVA+F +D+D+ICRAHQ+V +GY++ ++T++S Sbjct: 220 PDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFS 279 Query: 259 APNYCYRCGNVAAILELDEHLQKDFIIFEAA 289 APNYC N A++ +DE L F I + A Sbjct: 280 APNYCGEFDNAGAMMSVDETLMCSFQILKPA 310 >gi|4506003 protein phosphatase 1, catalytic subunit, alpha isoform 1 [Homo sapiens] Length = 330 Score = 293 bits (750), Expect = 1e-79 Identities = 133/271 (49%), Positives = 194/271 (71%), Gaps = 2/271 (0%) Query: 20 IKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLF 79 + E+E++ LC K+REI + + + +++P+ +CGDIHGQ+YDL LF GG PE+NYLF Sbjct: 30 LTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLF 89 Query: 80 MGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTV 139 +GD+VDRG S+ET LLLA K++YP+ L+RGNHE I ++YGFYDEC R+Y ++ + Sbjct: 90 LGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRY-NIKL 148 Query: 140 WRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSD 199 W+ T+ F+ L ++AI+D KIFC HGGLSP +Q+++QIR I R +VP G +CDLLWSD Sbjct: 149 WKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSD 208 Query: 200 PE-DTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWS 258 P+ D GWG + RG + FG++VVA+F +D+D+ICRAHQ+V +GY++ ++T++S Sbjct: 209 PDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFS 268 Query: 259 APNYCYRCGNVAAILELDEHLQKDFIIFEAA 289 APNYC N A++ +DE L F I + A Sbjct: 269 APNYCGEFDNAGAMMSVDETLMCSFQILKPA 299 >gi|46249376 protein phosphatase 1, catalytic subunit, beta isoform 1 [Homo sapiens] Length = 327 Score = 288 bits (738), Expect = 3e-78 Identities = 134/286 (46%), Positives = 199/286 (69%), Gaps = 6/286 (2%) Query: 22 ESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMG 81 E+EV+ LC K+REI + + + +++P+ +CGDIHGQ+ DL LF GG PE NYLF+G Sbjct: 31 EAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLG 90 Query: 82 DFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWR 141 D+VDRG S+ET LLLA K++YP+ L+RGNHE I ++YGFYDEC R++ ++ +W+ Sbjct: 91 DYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRF-NIKLWK 149 Query: 142 YCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPE 201 T+ F+ L ++AI+D KIFC HGGLSP +Q+++QIR I R +VP G +CDLLWSDP+ Sbjct: 150 TFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPD 209 Query: 202 -DTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAP 260 D GWG + RG + FG+DVV++F +D+D+ICRAHQ+V +GY++ ++T++SAP Sbjct: 210 KDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAP 269 Query: 261 NYCYRCGNVAAILELDEHLQKDFIIFEAAPQETR----GIPSKKPV 302 NYC N ++ +DE L F I + + ++ + G+ S +PV Sbjct: 270 NYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAKYQYGGLNSGRPV 315 >gi|4506005 protein phosphatase 1, catalytic subunit, beta isoform 1 [Homo sapiens] Length = 327 Score = 288 bits (738), Expect = 3e-78 Identities = 134/286 (46%), Positives = 199/286 (69%), Gaps = 6/286 (2%) Query: 22 ESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMG 81 E+EV+ LC K+REI + + + +++P+ +CGDIHGQ+ DL LF GG PE NYLF+G Sbjct: 31 EAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLG 90 Query: 82 DFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWR 141 D+VDRG S+ET LLLA K++YP+ L+RGNHE I ++YGFYDEC R++ ++ +W+ Sbjct: 91 DYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRF-NIKLWK 149 Query: 142 YCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPE 201 T+ F+ L ++AI+D KIFC HGGLSP +Q+++QIR I R +VP G +CDLLWSDP+ Sbjct: 150 TFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPD 209 Query: 202 -DTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAP 260 D GWG + RG + FG+DVV++F +D+D+ICRAHQ+V +GY++ ++T++SAP Sbjct: 210 KDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAP 269 Query: 261 NYCYRCGNVAAILELDEHLQKDFIIFEAAPQETR----GIPSKKPV 302 NYC N ++ +DE L F I + + ++ + G+ S +PV Sbjct: 270 NYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAKYQYGGLNSGRPV 315 >gi|45827798 protein phosphatase 1, catalytic subunit, alpha isoform 2 [Homo sapiens] Length = 286 Score = 266 bits (680), Expect = 2e-71 Identities = 123/238 (51%), Positives = 171/238 (71%), Gaps = 2/238 (0%) Query: 53 GDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIR 112 GDIHGQ+YDL LF GG PE+NYLF+GD+VDRG S+ET LLLA K++YP+ L+R Sbjct: 19 GDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLR 78 Query: 113 GNHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQ 172 GNHE I ++YGFYDEC R+Y ++ +W+ T+ F+ L ++AI+D KIFC HGGLSP +Q Sbjct: 79 GNHECASINRIYGFYDECKRRY-NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQ 137 Query: 173 TLDQIRTIDRKQEVPHDGPMCDLLWSDPE-DTTGWGVSPRGAGYLFGSDVVAQFNAANDI 231 +++QIR I R +VP G +CDLLWSDP+ D GWG + RG + FG++VVA+F +D+ Sbjct: 138 SMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDL 197 Query: 232 DMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAA 289 D+ICRAHQ+V +GY++ ++T++SAPNYC N A++ +DE L F I + A Sbjct: 198 DLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPA 255 >gi|194688147 protein phosphatase 3, catalytic subunit, alpha isoform isoform 2 [Homo sapiens] Length = 511 Score = 224 bits (572), Expect = 6e-59 Identities = 117/274 (42%), Positives = 167/274 (60%), Gaps = 15/274 (5%) Query: 20 IKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLF 79 ++ES + + IL +E N+ +D+PVTVCGDIHGQF+DL +LF VGG T YLF Sbjct: 56 LEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLF 115 Query: 80 MGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTV 139 +GD+VDRG++S+E L L ALK+ YP + L+RGNHE R +T+ + F EC KY S V Sbjct: 116 LGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKY-SERV 174 Query: 140 WRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSD 199 + C + FD L L+A+++ + CVHGGLSP I TLD IR +DR +E P GPMCD+LWSD Sbjct: 175 YDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSD 234 Query: 200 PEDTTG--------WGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNE 251 P + G + RG Y + V +F N++ I RAH+ GY+ + Sbjct: 235 PLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKS 294 Query: 252 ------TVLTVWSAPNYCYRCGNVAAILELDEHL 279 +++T++SAPNY N AA+L+ + ++ Sbjct: 295 QTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNV 328 >gi|6715568 protein phosphatase 3, catalytic subunit, alpha isoform isoform 1 [Homo sapiens] Length = 521 Score = 224 bits (572), Expect = 6e-59 Identities = 117/274 (42%), Positives = 167/274 (60%), Gaps = 15/274 (5%) Query: 20 IKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLF 79 ++ES + + IL +E N+ +D+PVTVCGDIHGQF+DL +LF VGG T YLF Sbjct: 56 LEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLF 115 Query: 80 MGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTV 139 +GD+VDRG++S+E L L ALK+ YP + L+RGNHE R +T+ + F EC KY S V Sbjct: 116 LGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKY-SERV 174 Query: 140 WRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSD 199 + C + FD L L+A+++ + CVHGGLSP I TLD IR +DR +E P GPMCD+LWSD Sbjct: 175 YDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSD 234 Query: 200 PEDTTG--------WGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNE 251 P + G + RG Y + V +F N++ I RAH+ GY+ + Sbjct: 235 PLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKS 294 Query: 252 ------TVLTVWSAPNYCYRCGNVAAILELDEHL 279 +++T++SAPNY N AA+L+ + ++ Sbjct: 295 QTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNV 328 >gi|215272354 protein phosphatase 3, catalytic subunit, beta isoform c [Homo sapiens] Length = 515 Score = 224 bits (571), Expect = 7e-59 Identities = 125/298 (41%), Positives = 175/298 (58%), Gaps = 23/298 (7%) Query: 3 EISDLDR--QIEQLRRCELIKESEVKALCA-----KAREILVEESNVQRVDSPVTVCGDI 55 E+ DLD +++ L+ L+KE V A + IL E + V++P+TVCGDI Sbjct: 42 EVFDLDGIPRVDVLKN-HLVKEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDI 100 Query: 56 HGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNH 115 HGQF+DL +LF VGG T YLF+GD+VDRG++S+E L L LK+ YP + L+RGNH Sbjct: 101 HGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNH 160 Query: 116 ESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLD 175 E R +T+ + F EC KY S V+ C E FD L L+A+++ + CVHGGLSP I TLD Sbjct: 161 ECRHLTEYFTFKQECKIKY-SERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLD 219 Query: 176 QIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSP--------RGAGYLFGSDVVAQFNA 227 IR +DR +E P GPMCDLLWSDP + G S RG Y + V +F Sbjct: 220 DIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQ 279 Query: 228 ANDIDMICRAHQLVMEGYKWHFNE------TVLTVWSAPNYCYRCGNVAAILELDEHL 279 N++ I RAH+ GY+ + +++T++SAPNY N AA+L+ + ++ Sbjct: 280 NNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNV 337 >gi|215272352 protein phosphatase 3, catalytic subunit, beta isoform a [Homo sapiens] Length = 525 Score = 224 bits (571), Expect = 7e-59 Identities = 125/298 (41%), Positives = 175/298 (58%), Gaps = 23/298 (7%) Query: 3 EISDLDR--QIEQLRRCELIKESEVKALCA-----KAREILVEESNVQRVDSPVTVCGDI 55 E+ DLD +++ L+ L+KE V A + IL E + V++P+TVCGDI Sbjct: 42 EVFDLDGIPRVDVLKN-HLVKEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDI 100 Query: 56 HGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNH 115 HGQF+DL +LF VGG T YLF+GD+VDRG++S+E L L LK+ YP + L+RGNH Sbjct: 101 HGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNH 160 Query: 116 ESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLD 175 E R +T+ + F EC KY S V+ C E FD L L+A+++ + CVHGGLSP I TLD Sbjct: 161 ECRHLTEYFTFKQECKIKY-SERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLD 219 Query: 176 QIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSP--------RGAGYLFGSDVVAQFNA 227 IR +DR +E P GPMCDLLWSDP + G S RG Y + V +F Sbjct: 220 DIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQ 279 Query: 228 ANDIDMICRAHQLVMEGYKWHFNE------TVLTVWSAPNYCYRCGNVAAILELDEHL 279 N++ I RAH+ GY+ + +++T++SAPNY N AA+L+ + ++ Sbjct: 280 NNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNV 337 >gi|11036640 protein phosphatase 3, catalytic subunit, beta isoform b [Homo sapiens] Length = 524 Score = 224 bits (571), Expect = 7e-59 Identities = 125/298 (41%), Positives = 175/298 (58%), Gaps = 23/298 (7%) Query: 3 EISDLDR--QIEQLRRCELIKESEVKALCA-----KAREILVEESNVQRVDSPVTVCGDI 55 E+ DLD +++ L+ L+KE V A + IL E + V++P+TVCGDI Sbjct: 42 EVFDLDGIPRVDVLKN-HLVKEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDI 100 Query: 56 HGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNH 115 HGQF+DL +LF VGG T YLF+GD+VDRG++S+E L L LK+ YP + L+RGNH Sbjct: 101 HGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNH 160 Query: 116 ESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLD 175 E R +T+ + F EC KY S V+ C E FD L L+A+++ + CVHGGLSP I TLD Sbjct: 161 ECRHLTEYFTFKQECKIKY-SERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLD 219 Query: 176 QIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSP--------RGAGYLFGSDVVAQFNA 227 IR +DR +E P GPMCDLLWSDP + G S RG Y + V +F Sbjct: 220 DIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQ 279 Query: 228 ANDIDMICRAHQLVMEGYKWHFNE------TVLTVWSAPNYCYRCGNVAAILELDEHL 279 N++ I RAH+ GY+ + +++T++SAPNY N AA+L+ + ++ Sbjct: 280 NNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNV 337 >gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens] Length = 499 Score = 221 bits (562), Expect = 8e-58 Identities = 123/292 (42%), Positives = 173/292 (59%), Gaps = 12/292 (4%) Query: 15 RRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPE 74 R+C +VK + +K ++ E+ ++ + +TVCGD HGQFYDL +F + G E Sbjct: 206 RKCAYQILVQVKEVLSKLSTLV--ETTLKETEK-ITVCGDTHGQFYDLLNIFELNGLPSE 262 Query: 75 TN-YLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRK 133 TN Y+F GDFVDRG +SVE L L K+ YPD L+RGNHE+ + Q+YGF E K Sbjct: 263 TNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAK 322 Query: 134 YGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGL-SPSIQTLDQIRTIDRKQEVPHDGPM 192 Y + ++ +E+F++L L+ I+GK+ +HGGL S TLD IR I+R ++ P GPM Sbjct: 323 Y-TAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPM 381 Query: 193 CDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNET 252 CDLLWSDP+ G +S RG FG DV F N++D I R+H++ EGY+ Sbjct: 382 CDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGR 441 Query: 253 VLTVWSAPNYCYRCGNVAAILELD-EHLQKDFIIFEAAPQETRGIPSKKPVA 303 +TV+SAPNYC + GN A+ + L L+ F F A P P+ KP+A Sbjct: 442 CVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPH-----PNVKPMA 488 >gi|194688149 protein phosphatase 3, catalytic subunit, alpha isoform isoform 3 [Homo sapiens] Length = 469 Score = 219 bits (558), Expect = 2e-57 Identities = 113/257 (43%), Positives = 158/257 (61%), Gaps = 15/257 (5%) Query: 20 IKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLF 79 ++ES + + IL +E N+ +D+PVTVCGDIHGQF+DL +LF VGG T YLF Sbjct: 56 LEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLF 115 Query: 80 MGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTV 139 +GD+VDRG++S+E L L ALK+ YP + L+RGNHE R +T+ + F EC KY S V Sbjct: 116 LGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKY-SERV 174 Query: 140 WRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSD 199 + C + FD L L+A+++ + CVHGGLSP I TLD IR +DR +E P GPMCD+LWSD Sbjct: 175 YDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSD 234 Query: 200 PEDTTG--------WGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNE 251 P + G + RG Y + V +F N++ I RAH+ GY+ + Sbjct: 235 PLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKS 294 Query: 252 ------TVLTVWSAPNY 262 +++T++SAPNY Sbjct: 295 QTTGFPSLITIFSAPNY 311 >gi|21361290 protein phosphatase 3, catalytic subunit, gamma [Homo sapiens] Length = 512 Score = 215 bits (547), Expect = 5e-56 Identities = 111/259 (42%), Positives = 158/259 (61%), Gaps = 15/259 (5%) Query: 35 ILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETF 94 IL +E + VD+P+TVCGDIHGQF+DL +LF VGG T YLF+GD+VDRG++S+E Sbjct: 67 ILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGYFSIECV 126 Query: 95 LLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSA 154 L L +LK+ +P + L+RGNHE R +T + F EC KY S V+ C E FD L L+A Sbjct: 127 LYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKY-SEQVYDACMETFDCLPLAA 185 Query: 155 IIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTG--------W 206 +++ + CVHGG+SP I +LD IR +DR E P GP+CDLLWSDP + G Sbjct: 186 LLNQQFLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEKTLEHYT 245 Query: 207 GVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNE------TVLTVWSAP 260 + RG Y + V +F N++ I RAH+ GY+ + +++T++SAP Sbjct: 246 HNTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAP 305 Query: 261 NYCYRCGNVAAILELDEHL 279 NY N AA+L+ + ++ Sbjct: 306 NYLDVYNNKAAVLKYENNV 324 >gi|239752750 PREDICTED: similar to protein phosphatase 2, catalytic subunit, alpha [Homo sapiens] Length = 384 Score = 208 bits (530), Expect = 4e-54 Identities = 111/251 (44%), Positives = 150/251 (59%), Gaps = 55/251 (21%) Query: 24 EVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDF 83 +VK+LC +A+EIL EESN Q V PVTV GD HGQ GD+ Sbjct: 176 KVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHGQ----------------------GDY 213 Query: 84 VDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWRYC 143 +DRG+YS+E +LLLA+KV Y + +T++ NHESRQITQVY Y+ECLRK+G Sbjct: 214 IDRGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHG-------- 265 Query: 144 TEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDT 203 +A DG++FC+HGGLSPS+ TL IRT++ Q++PH+GPM DLL+SDP+D Sbjct: 266 ---------NANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDPDD- 315 Query: 204 TGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYC 263 D FN A+ + ++ RAHQLVM G+ W + V+ ++S PNYC Sbjct: 316 ---------------HDTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYC 360 Query: 264 YRCGNVAAILE 274 Y CG +A L+ Sbjct: 361 YHCGGMALALQ 371 >gi|239747318 PREDICTED: similar to protein phosphatase 2, catalytic subunit, alpha [Homo sapiens] Length = 254 Score = 205 bits (521), Expect = 5e-53 Identities = 109/244 (44%), Positives = 146/244 (59%), Gaps = 55/244 (22%) Query: 24 EVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDF 83 +VK+LC +A+EIL EESN Q V PVTV GD HGQ GD+ Sbjct: 55 KVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHGQ----------------------GDY 92 Query: 84 VDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWRYC 143 +DRG+YS+E +LLLA+KV Y + +T++ NHESRQITQVY Y+ECLRK+G Sbjct: 93 IDRGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHG-------- 144 Query: 144 TEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDT 203 +A DG++FC+HGGLSPS+ TL IRT++ Q++PH+GPM DLL+SDP+D Sbjct: 145 ---------NANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDPDD- 194 Query: 204 TGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYC 263 D FN A+ + ++ RAHQLVM G+ W + V+ ++S PNYC Sbjct: 195 ---------------HDTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYC 239 Query: 264 YRCG 267 Y CG Sbjct: 240 YHCG 243 >gi|239741140 PREDICTED: similar to protein phosphatase 2, catalytic subunit, alpha [Homo sapiens] Length = 254 Score = 205 bits (521), Expect = 5e-53 Identities = 109/244 (44%), Positives = 146/244 (59%), Gaps = 55/244 (22%) Query: 24 EVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDF 83 +VK+LC +A+EIL EESN Q V PVTV GD HGQ GD+ Sbjct: 55 KVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHGQ----------------------GDY 92 Query: 84 VDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWRYC 143 +DRG+YS+E +LLLA+KV Y + +T++ NHESRQITQVY Y+ECLRK+G Sbjct: 93 IDRGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHG-------- 144 Query: 144 TEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDT 203 +A DG++FC+HGGLSPS+ TL IRT++ Q++PH+GPM DLL+SDP+D Sbjct: 145 ---------NANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDPDD- 194 Query: 204 TGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYC 263 D FN A+ + ++ RAHQLVM G+ W + V+ ++S PNYC Sbjct: 195 ---------------HDTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYC 239 Query: 264 YRCG 267 Y CG Sbjct: 240 YHCG 243 >gi|23312374 protein phosphatase with EF hand calcium-binding domain 1 isoform 1b [Homo sapiens] Length = 625 Score = 133 bits (335), Expect = 2e-31 Identities = 89/295 (30%), Positives = 149/295 (50%), Gaps = 25/295 (8%) Query: 5 SDLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSP----VTVCGDIHGQFY 60 +D+D +E + +++ V + + +++L + N + + VT+CGD+HG+ Sbjct: 119 TDIDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLD 178 Query: 61 DLKELFRVGGDVPETN-YLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQ 119 DL +F G E N Y+F GDFVDRG S+E ++L + YP+ + L RGNHE Sbjct: 179 DLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFM 238 Query: 120 ITQVYGFYDECLRKY--GSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQI 177 + YGF E L KY + + E + +L + I+D +I +HGG+S + L+ + Sbjct: 239 MNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTD-LNLL 297 Query: 178 RTIDRKQE----VP-------HD-----GPMCDLLWSDPEDTTG-WGVSPRGAGYLFGSD 220 ++R + +P HD + D+LWSDP G + + RG G FG D Sbjct: 298 HRVERNKMKSVLIPPTETNRDHDTDSKHNKIIDILWSDPRGKNGCFPNTCRGGGCYFGPD 357 Query: 221 VVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILEL 275 V ++ + M+ R+H+ EGY+ + V+T++SA NY N A ++L Sbjct: 358 VTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAYIKL 412 >gi|23312380 protein phosphatase with EF hand calcium-binding domain 1 isoform 1 [Homo sapiens] Length = 653 Score = 122 bits (305), Expect = 5e-28 Identities = 89/323 (27%), Positives = 149/323 (46%), Gaps = 53/323 (16%) Query: 5 SDLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSP----VTVCGDIHGQFY 60 +D+D +E + +++ V + + +++L + N + + VT+CGD+HG+ Sbjct: 119 TDIDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLD 178 Query: 61 DLKELFRVGGDVPETN-YLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQ 119 DL +F G E N Y+F GDFVDRG S+E ++L + YP+ + L RGNHE Sbjct: 179 DLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFM 238 Query: 120 ITQVYGFYDECLRKY--GSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQI 177 + YGF E L KY + + E + +L + I+D +I +HGG+S + L+ + Sbjct: 239 MNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTD-LNLL 297 Query: 178 RTIDRKQE----VP-------HD---------------------------------GPMC 193 ++R + +P HD + Sbjct: 298 HRVERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQII 357 Query: 194 DLLWSDPEDTTG-WGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNET 252 D+LWSDP G + + RG G FG DV ++ + M+ R+H+ EGY+ + Sbjct: 358 DILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGK 417 Query: 253 VLTVWSAPNYCYRCGNVAAILEL 275 V+T++SA NY N A ++L Sbjct: 418 VVTIFSASNYYEEGSNRGAYIKL 440 >gi|23312386 serine/threonine protein phosphatase with EF-hand motifs 2 [Homo sapiens] Length = 753 Score = 107 bits (268), Expect = 1e-23 Identities = 67/183 (36%), Positives = 99/183 (54%), Gaps = 8/183 (4%) Query: 11 IEQLRRCELIKESEVKALCAKAREILVEESNVQRVDS----PVTVCGDIHGQFYDLKELF 66 +E R + + V L + ++ LV+ N+ RV + +TVCGD+HGQ DL +F Sbjct: 132 VEAFRLKQQLHARYVLNLLYETKKHLVQLPNINRVSTCYSEEITVCGDLHGQLDDLIFIF 191 Query: 67 RVGG-DVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYG 125 G PE +Y+F GDFVDRG SVE ++L A + YP L RGNHE + YG Sbjct: 192 YKNGLPSPERSYVFNGDFVDRGKDSVEILMILFAFMLVYPKEFHLNRGNHEDHMVNLRYG 251 Query: 126 FYDECLRKY--GSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRK 183 F E + KY + R ++F +L L+ +ID K+ +HGG+S I L+ + I+R Sbjct: 252 FTKEVMNKYKVHGKEILRTLQDVFCWLPLATLIDEKVLILHGGVS-DITDLELLDKIERS 310 Query: 184 QEV 186 + V Sbjct: 311 KIV 313 Score = 57.0 bits (136), Expect = 2e-08 Identities = 33/96 (34%), Positives = 49/96 (51%), Gaps = 1/96 (1%) Query: 194 DLLWSDPEDTTGWGVSP-RGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNET 252 D+LWSDP G + RG G FG DV Q ++ + R+H+ EGY++ N Sbjct: 443 DILWSDPMAQEGCKANTIRGGGCYFGPDVTQQLLQKYNMQFLIRSHECKPEGYEFCHNRK 502 Query: 253 VLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEA 288 VLT++SA NY N A ++L L + ++A Sbjct: 503 VLTIFSASNYYEVGSNRGAYVKLGPALTPHIVQYQA 538 >gi|23312378 protein phosphatase with EF hand calcium-binding domain 1 isoform 3 [Homo sapiens] Length = 591 Score = 98.6 bits (244), Expect = 6e-21 Identities = 77/278 (27%), Positives = 129/278 (46%), Gaps = 25/278 (8%) Query: 5 SDLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSP----VTVCGDIHGQFY 60 +D+D +E + +++ V + + +++L + N + + VT+CGD+HG+ Sbjct: 119 TDIDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLD 178 Query: 61 DLKELFRVGGDVPETN-YLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQ 119 DL +F G E N Y+F GDFVDRG S+E ++L + YP+ + L RGNHE Sbjct: 179 DLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFM 238 Query: 120 ITQVYGFYDECLRKY--GSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQI 177 + YGF E L KY + + E + +L + I+D +I +HGG+S + L+ + Sbjct: 239 MNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTD-LNLL 297 Query: 178 RTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRA 237 ++R + M +L E + + V FNA I + Sbjct: 298 HRVERNK-------MKSVLIPPTETNRDHDTDSK------HNKVGVTFNAHGRI----KT 340 Query: 238 HQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILEL 275 + E H E V+T++SA NY N A ++L Sbjct: 341 NGSPTEHLTEHEWEQVVTIFSASNYYEEGSNRGAYIKL 378 >gi|8393264 delta-like 3 protein isoform 1 precursor [Homo sapiens] Length = 618 Score = 29.6 bits (65), Expect = 3.5 Identities = 17/57 (29%), Positives = 24/57 (42%) Query: 165 GGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDV 221 G PS+ L R QE DGP + W+ PED G+ A ++ +V Sbjct: 531 GTPEPSVHALPDALNNLRTQEGSGDGPSSSVDWNRPEDVDPQGIYVISAPSIYAREV 587 >gi|38679914 mitochondrial distribution and morphology 20 [Homo sapiens] Length = 972 Score = 29.3 bits (64), Expect = 4.6 Identities = 14/74 (18%), Positives = 34/74 (45%) Query: 91 VETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYL 150 VE + ++L +Y + + +IRG + +++ ++C+ Y ++ W C + L Sbjct: 196 VELYYMILERLGKYQEALDVIRGKLGEKLTSEIQSRENKCMAMYKKLSRWPECNALSRRL 255 Query: 151 SLSAIIDGKIFCVH 164 L D + + + Sbjct: 256 LLKNSDDWQFYLTY 269 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.323 0.141 0.440 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,928,363 Number of Sequences: 37866 Number of extensions: 517301 Number of successful extensions: 1042 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 32 Number of HSP's successfully gapped in prelim test: 1 Number of HSP's that attempted gapping in prelim test: 950 Number of HSP's gapped (non-prelim): 36 length of query: 307 length of database: 18,247,518 effective HSP length: 102 effective length of query: 205 effective length of database: 14,385,186 effective search space: 2948963130 effective search space used: 2948963130 T: 11 A: 40 X1: 16 ( 7.5 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (22.0 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.