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Search of human proteins with 4505007
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4505007 LIM homeobox transcription factor 1, beta [Homo
sapiens]
(372 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4505007 LIM homeobox transcription factor 1, beta [Homo sapiens] 765 0.0
gi|28893581 LIM homeobox transcription factor 1, alpha isoform a... 504 e-143
gi|11641283 LIM homeobox protein 5 [Homo sapiens] 196 2e-50
gi|30410785 LIM homeobox protein 1 [Homo sapiens] 194 1e-49
gi|30023847 LIM homeobox protein 3 isoform a [Homo sapiens] 182 4e-46
gi|15375314 LIM homeobox protein 4 [Homo sapiens] 182 6e-46
gi|7657303 LIM homeobox protein 3 isoform b [Homo sapiens] 177 1e-44
gi|21956641 ISL LIM homeobox 2 [Homo sapiens] 177 2e-44
gi|115387114 islet-1 [Homo sapiens] 166 4e-41
gi|50083287 LIM homeobox 8 [Homo sapiens] 165 5e-41
gi|134284361 LIM homeobox protein 6 isoform 2 [Homo sapiens] 159 5e-39
gi|134284359 LIM homeobox protein 6 isoform 1 [Homo sapiens] 156 3e-38
gi|33569216 LIM homeobox 9 isoform 1 [Homo sapiens] 144 2e-34
gi|62241033 LIM homeobox 9 isoform 2 [Homo sapiens] 144 2e-34
gi|41281895 LIM homeobox transcription factor 1, alpha isoform b... 142 5e-34
gi|30795196 LIM homeobox protein 2 [Homo sapiens] 130 1e-30
gi|75677381 LIM homeobox transcription factor 1, alpha isoform c... 120 3e-27
gi|21361802 LIM domain only 3 [Homo sapiens] 109 5e-24
gi|47778935 LIM domain only 3 [Homo sapiens] 109 5e-24
gi|4505005 LIM domain only 1 [Homo sapiens] 107 1e-23
gi|5803072 LIM domain only 4 [Homo sapiens] 105 9e-23
gi|214832219 LIM domain only 2 isoform 2 [Homo sapiens] 89 5e-18
gi|214832121 LIM domain only 2 isoform 2 [Homo sapiens] 89 5e-18
gi|214832074 LIM domain only 2 isoform 1 [Homo sapiens] 89 5e-18
gi|4505001 LIM domain kinase 1 [Homo sapiens] 81 2e-15
gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens] 77 2e-14
gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens] 77 2e-14
gi|5031869 LIM domain kinase 2 isoform 2a [Homo sapiens] 74 2e-13
gi|51173713 actin-binding LIM protein 1 isoform b [Homo sapiens] 73 4e-13
gi|51173711 actin-binding LIM protein 1 isoform a [Homo sapiens] 73 4e-13
>gi|4505007 LIM homeobox transcription factor 1, beta [Homo sapiens]
Length = 372
Score = 765 bits (1975), Expect = 0.0
Identities = 372/372 (100%), Positives = 372/372 (100%)
Query: 1 MLDGIKMEEHALRPGPATLGVLLGSDCPHPAVCEGCQRPISDRFLMRVNESSWHEECLQC 60
MLDGIKMEEHALRPGPATLGVLLGSDCPHPAVCEGCQRPISDRFLMRVNESSWHEECLQC
Sbjct: 1 MLDGIKMEEHALRPGPATLGVLLGSDCPHPAVCEGCQRPISDRFLMRVNESSWHEECLQC 60
Query: 61 AACQQALTTSCYFRDRKLYCKQDYQQLFAAKCSGCMEKIAPTEFVMRALECVYHLGCFCC 120
AACQQALTTSCYFRDRKLYCKQDYQQLFAAKCSGCMEKIAPTEFVMRALECVYHLGCFCC
Sbjct: 61 AACQQALTTSCYFRDRKLYCKQDYQQLFAAKCSGCMEKIAPTEFVMRALECVYHLGCFCC 120
Query: 121 CVCERQLRKGDEFVLKEGQLLCKGDYEKEKDLLSSVSPDESDSVKSEDEDGDMKPAKGQG 180
CVCERQLRKGDEFVLKEGQLLCKGDYEKEKDLLSSVSPDESDSVKSEDEDGDMKPAKGQG
Sbjct: 121 CVCERQLRKGDEFVLKEGQLLCKGDYEKEKDLLSSVSPDESDSVKSEDEDGDMKPAKGQG 180
Query: 181 SQSKGSGDDGKDPRRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVV 240
SQSKGSGDDGKDPRRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVV
Sbjct: 181 SQSKGSGDDGKDPRRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVV 240
Query: 241 QVWFQNQRAKMKKLARRHQQQQEQQNSQRLGQEVLSSRMEGMMASYTPLAPPQQQIVAME 300
QVWFQNQRAKMKKLARRHQQQQEQQNSQRLGQEVLSSRMEGMMASYTPLAPPQQQIVAME
Sbjct: 241 QVWFQNQRAKMKKLARRHQQQQEQQNSQRLGQEVLSSRMEGMMASYTPLAPPQQQIVAME 300
Query: 301 QSPYGSSDPFQQGLTPPQMPGNDSIFHDIDSDTSLTSLSDCFLGSSDVGSLQARVGNPID 360
QSPYGSSDPFQQGLTPPQMPGNDSIFHDIDSDTSLTSLSDCFLGSSDVGSLQARVGNPID
Sbjct: 301 QSPYGSSDPFQQGLTPPQMPGNDSIFHDIDSDTSLTSLSDCFLGSSDVGSLQARVGNPID 360
Query: 361 RLYSMQSSYFAS 372
RLYSMQSSYFAS
Sbjct: 361 RLYSMQSSYFAS 372
>gi|28893581 LIM homeobox transcription factor 1, alpha isoform a
[Homo sapiens]
Length = 382
Score = 504 bits (1297), Expect = e-143
Identities = 260/387 (67%), Positives = 307/387 (79%), Gaps = 20/387 (5%)
Query: 1 MLDGIKMEEH--ALRPGPATLGVLLGSDCPHPAVCEGCQRPISDRFLMRVNESSWHEECL 58
MLDG+KMEE+ + A+ LLG +VCEGCQR I DRFL+R+N+S WHE+C+
Sbjct: 1 MLDGLKMEENFQSAIDTSASFSSLLGRAVSPKSVCEGCQRVILDRFLLRLNDSFWHEQCV 60
Query: 59 QCAACQQALTTSCYFRDRKLYCKQDYQQLFAAKCSGCMEKIAPTEFVMRALECVYHLGCF 118
QCA+C++ L T+C++RD+KLYCK DY++LFA KC GC E IAP EFVMRA + VYHL CF
Sbjct: 61 QCASCKEPLETTCFYRDKKLYCKYDYEKLFAVKCGGCFEAIAPNEFVMRAQKSVYHLSCF 120
Query: 119 CCCVCERQLRKGDEFVLKEGQLLCKGDYEKEKDLLSSVSPDESDSVKSEDEDGDMKPAKG 178
CCCVCERQL+KGDEFVLKEGQLLCKGDYEKE++LLS VSP SDS KS+DE+ K A G
Sbjct: 121 CCCVCERQLQKGDEFVLKEGQLLCKGDYEKERELLSLVSPAASDSGKSDDEESLCKSAHG 180
Query: 179 QGSQSKGSGDDGKDPRRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVR 238
G KG+ ++GKD +RPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVR
Sbjct: 181 AG---KGTAEEGKDHKRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVR 237
Query: 239 VVQVWFQNQRAKMKKLARR-HQQQQEQQNSQRLGQEVL----SSRMEGMMASYTPLAPPQ 293
VVQVWFQNQRAKMKKLARR QQQQ+QQN+QRL S+ MEG+M YT L P
Sbjct: 238 VVQVWFQNQRAKMKKLARRQQQQQQDQQNTQRLSSAQTNGGGSAGMEGIMNPYTAL-PTP 296
Query: 294 QQIVAMEQSPYGSSDPFQQGLTPPQMPGN-------DSIFHDIDS-DTSLTSLSDCFLGS 345
QQ++A+EQS Y SSDPF+QGLTPPQMPG+ + +FHD+DS DTSL++L DCFL +
Sbjct: 297 QQLLAIEQSVY-SSDPFRQGLTPPQMPGDHMHPYGAEPLFHDLDSDDTSLSNLGDCFLAT 355
Query: 346 SDVGSLQARVGNPIDRLYSMQSSYFAS 372
S+ G LQ+RVGNPID LYSMQ+SYF S
Sbjct: 356 SEAGPLQSRVGNPIDHLYSMQNSYFTS 382
>gi|11641283 LIM homeobox protein 5 [Homo sapiens]
Length = 402
Score = 196 bits (499), Expect = 2e-50
Identities = 116/346 (33%), Positives = 183/346 (52%), Gaps = 37/346 (10%)
Query: 33 CEGCQRPISDRFLMRVNESSWHEECLQCAACQQALTTSCYFRDRKLYCKQDYQQLFAAKC 92
C GC+RPI DRFL+ V + +WH +C+QC C+ L+ C+ R+ KLYCK D+ + F KC
Sbjct: 5 CAGCERPILDRFLLNVLDRAWHIKCVQCCECKTNLSEKCFSREGKLYCKNDFFRRFGTKC 64
Query: 93 SGCMEKIAPTEFVMRALECVYHLGCFCCCVCERQLRKGDE-FVLKEGQLLCKGDYEKEKD 151
+GC + I+P++ V +A V+HL CF C VC +QL G+E +V+ E + +CK DY
Sbjct: 65 AGCAQGISPSDLVRKARSKVFHLNCFTCMVCNKQLSTGEELYVIDENKFVCKDDYLSSSS 124
Query: 152 LLS------------SVSPDESDSVKSEDEDGDMKPAKGQGSQSKGSGDDGKDPRRPKRP 199
L S+SPD D+++ + ++ D + + + + + + +R + P
Sbjct: 125 LKEGSLNSVSSCTDRSLSPDLQDALQDDPKETDNSTSSDKETANNENEEQNSGTKR-RGP 183
Query: 200 RTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKL----- 254
RT + +Q KA+F + KP R +RE LA ETGL++RV+QVWFQN+R+K +++
Sbjct: 184 RTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRMKQLSA 243
Query: 255 --ARRHQQQQEQQNSQRLGQEVLSSRMEGMMASYTPLAPPQQQIVAMEQSPYGSSDPFQQ 312
ARRH + + + LG + S M G YT Q A P + D F
Sbjct: 244 LGARRHAFFRSPRRMRPLGGRLDESEMLG-STPYTYYGDYQGDYYA----PGSNYDFFAH 298
Query: 313 GLTPPQMPGNDSIFHDIDSDTSLTSLSDCFLGSSDVGSLQARVGNP 358
G PP + +D+S + S GS+ +G+L+ + P
Sbjct: 299 G--PPSQAQS-------PADSSFLAASG--PGSTPLGALEPPLAGP 333
>gi|30410785 LIM homeobox protein 1 [Homo sapiens]
Length = 406
Score = 194 bits (493), Expect = 1e-49
Identities = 98/247 (39%), Positives = 146/247 (59%), Gaps = 22/247 (8%)
Query: 33 CEGCQRPISDRFLMRVNESSWHEECLQCAACQQALTTSCYFRDRKLYCKQDYQQLFAAKC 92
C GC+RPI DRFL+ V + +WH +C+QC C+ LT C+ R+ KLYCK D+ + F KC
Sbjct: 4 CAGCKRPILDRFLLNVLDRAWHVKCVQCCECKCNLTEKCFSREGKLYCKNDFFRCFGTKC 63
Query: 93 SGCMEKIAPTEFVMRALECVYHLGCFCCCVCERQLRKGDE-FVLKEGQLLCKGDY----- 146
+GC + I+P++ V RA V+HL CF C +C +QL G+E +++ E + +CK DY
Sbjct: 64 AGCAQGISPSDLVRRARSKVFHLNCFTCMMCNKQLSTGEELYIIDENKFVCKEDYLSNSS 123
Query: 147 -EKEKDLLS-------SVSPDESDSVKSEDEDGDMKPAKGQGSQSKGSGDDGKDPRRPKR 198
KE L S S+SPD D + + +D + + + S + D +R +
Sbjct: 124 VAKENSLHSATTGSDPSLSPDSQDPSQDDAKDSESANVSDKEAGSNENDDQNLGAKR-RG 182
Query: 199 PRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKL---- 254
PRT + +Q KA+F + KP R +RE LA ETGL++RV+QVWFQN+R+K +++
Sbjct: 183 PRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRMKQLS 242
Query: 255 ---ARRH 258
ARRH
Sbjct: 243 ALGARRH 249
>gi|30023847 LIM homeobox protein 3 isoform a [Homo sapiens]
Length = 397
Score = 182 bits (462), Expect = 4e-46
Identities = 117/332 (35%), Positives = 161/332 (48%), Gaps = 52/332 (15%)
Query: 7 MEEHALRPGPATLGVLLGS-DCPHPAVCEGCQRPISDRFLMRVNESSWHEECLQCAACQQ 65
+E RPG A + L G+ + P +C GC + I DRF+++ + WH +CL+C+ C
Sbjct: 7 LERDRARPGAAAVCTLGGTREIP---LCAGCDQHILDRFILKALDRHWHSKCLKCSDCHT 63
Query: 66 ALTTSCYFRDRKLYCKQDYQQLFAAKCSGCMEKIAPTEFVMRALECVYHLGCFCCCVCER 125
L C+ R +YCK D+ + F KC+ C I PT+ V RA + VYHL CF C VC+R
Sbjct: 64 PLAERCFSRGESVYCKDDFFKRFGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKR 123
Query: 126 QLRKGDEFVLKE-GQLLCKGDYEKEKDLLSSVSPDESDSVKSEDEDGDMKPAKGQGSQSK 184
QL GDEF L E +L+CK DYE K + +
Sbjct: 124 QLATGDEFYLMEDSRLVCKADYETAKQREAEAT--------------------------- 156
Query: 185 GSGDDGKDPRRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWF 244
KRPRT +T +Q K+++ S KP R VRE L++ETGL +RVVQVWF
Sbjct: 157 -----------AKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWF 205
Query: 245 QNQRAKMKKL---ARRHQQQQEQQNSQRL---GQEVLSSRMEGMMASYTPLAPPQQQIVA 298
QN+RAK K+L A R + Q +N +R + S EG + P + +
Sbjct: 206 QNRRAKEKRLKKDAGRQRWGQYFRNMKRSRGGSKSDKDSVQEGQDSDAEVSFPDEPSLAE 265
Query: 299 M--EQSPYGS-SDPFQQGLTPPQMPGNDSIFH 327
M YGS +P Q P GN S+ H
Sbjct: 266 MGPANGLYGSLGEPTQALGRPSGALGNFSLEH 297
>gi|15375314 LIM homeobox protein 4 [Homo sapiens]
Length = 390
Score = 182 bits (461), Expect = 6e-46
Identities = 104/265 (39%), Positives = 144/265 (54%), Gaps = 45/265 (16%)
Query: 9 EHALRPGPATLGVLLGSDCPHPAVCEGCQRPISDRFLMRVNESSWHEECLQCAACQQALT 68
E A++ P LGV + P C GC + I D+F+++V + WH CL+CA CQ L
Sbjct: 10 EGAVKGLPEMLGVPM-QQIPQ---CAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLA 65
Query: 69 TSCYFRDRKLYCKQDYQQLFAAKCSGCMEKIAPTEFVMRALECVYHLGCFCCCVCERQLR 128
C+ R +YCK+D+ + F KC+ C + I PT+ V +A + VYHL CF C +C RQL
Sbjct: 66 DRCFSRAGSVYCKEDFFKRFGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLA 125
Query: 129 KGDEFVLKE-GQLLCKGDYEKEKDLLSSVSPDESDSVKSEDEDGDMKPAKGQGSQSKGSG 187
GDEF L E G+L+CK DYE K D+S++
Sbjct: 126 TGDEFYLMEDGRLVCKEDYETAK------QNDDSEA------------------------ 155
Query: 188 DDGKDPRRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQ 247
KRPRT +T +Q K +++ S KP R VRE L++ETGL +RVVQVWFQN+
Sbjct: 156 -------GAKRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNR 208
Query: 248 RAKMKKL---ARRHQQQQEQQNSQR 269
RAK K+L A RH+ Q ++ +R
Sbjct: 209 RAKEKRLKKDAGRHRWGQFYKSVKR 233
>gi|7657303 LIM homeobox protein 3 isoform b [Homo sapiens]
Length = 402
Score = 177 bits (450), Expect = 1e-44
Identities = 109/306 (35%), Positives = 149/306 (48%), Gaps = 48/306 (15%)
Query: 32 VCEGCQRPISDRFLMRVNESSWHEECLQCAACQQALTTSCYFRDRKLYCKQDYQQLFAAK 91
+C GC + I DRF+++ + WH +CL+C+ C L C+ R +YCK D+ + F K
Sbjct: 35 LCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDDFFKRFGTK 94
Query: 92 CSGCMEKIAPTEFVMRALECVYHLGCFCCCVCERQLRKGDEFVLKE-GQLLCKGDYEKEK 150
C+ C I PT+ V RA + VYHL CF C VC+RQL GDEF L E +L+CK DYE K
Sbjct: 95 CAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYETAK 154
Query: 151 DLLSSVSPDESDSVKSEDEDGDMKPAKGQGSQSKGSGDDGKDPRRPKRPRTILTTQQRRA 210
+ + KRPRT +T +Q
Sbjct: 155 QREAEAT--------------------------------------AKRPRTTITAKQLET 176
Query: 211 FKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKL---ARRHQQQQEQQNS 267
K+++ S KP R VRE L++ETGL +RVVQVWFQN+RAK K+L A R + Q +N
Sbjct: 177 LKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRQRWGQYFRNM 236
Query: 268 QRL---GQEVLSSRMEGMMASYTPLAPPQQQIVAM--EQSPYGS-SDPFQQGLTPPQMPG 321
+R + S EG + P + + M YGS +P Q P G
Sbjct: 237 KRSRGGSKSDKDSVQEGQDSDAEVSFPDEPSLAEMGPANGLYGSLGEPTQALGRPSGALG 296
Query: 322 NDSIFH 327
N S+ H
Sbjct: 297 NFSLEH 302
>gi|21956641 ISL LIM homeobox 2 [Homo sapiens]
Length = 359
Score = 177 bits (448), Expect = 2e-44
Identities = 116/337 (34%), Positives = 172/337 (51%), Gaps = 22/337 (6%)
Query: 28 PHPAVCEGCQRPISDRFLMRVN-ESSWHEECLQCAACQQAL--TTSCYFRDRKLYCKQDY 84
P A+C GC I D+F++RV+ + WH CL+CA C Q L T +C+ RD K YCK+DY
Sbjct: 22 PGTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDY 81
Query: 85 QQLFAAKCSGCMEKIAPTEFVMRALECVYHLGCFCCCVCERQLRKGDEFVLKEGQLLCKG 144
+LF KC+ C + ++ VMRA + VYH+ CF C VC RQL GDEF L+E +LLC+
Sbjct: 82 VRLFGIKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLREHELLCRA 141
Query: 145 DYEKEKDLLSSVSPDESDSVKSEDEDGDMKPAKGQGSQSKGSGDDGKDPRRPKRPRTILT 204
D+ + ++ SP + G P G G Q K + R RT+L
Sbjct: 142 DHGLLLERAAAGSPRSPGPLPG--ARGLHLPDAGSGRQPALRPHVHKQTEKTTRVRTVLN 199
Query: 205 TQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRHQQQQEQ 264
+Q + + + +P ++E L TGLS RV++VWFQN+R K KK + +Q Q+Q
Sbjct: 200 EKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKKSILMKQLQQQ 259
Query: 265 QNSQRLGQEVLSSRMEGMMASYTPLAPPQQQIVAMEQSPYGSSDPFQQGLTPPQMPGNDS 324
Q+S + + L+ TPL + E + GS+ Q P + +
Sbjct: 260 QHSDKTSLQGLTG---------TPLVAGSP--IRHENAVQGSAVEVQTYQPPWKALSEFA 308
Query: 325 IFHDIDSDT--SLTSLSDC-FLGS---SDVGSLQARV 355
+ D+D L S S+ LG+ SDV SL +++
Sbjct: 309 LQSDLDQPAFQQLVSFSESGSLGNSSGSDVTSLSSQL 345
>gi|115387114 islet-1 [Homo sapiens]
Length = 349
Score = 166 bits (419), Expect = 4e-41
Identities = 107/337 (31%), Positives = 167/337 (49%), Gaps = 24/337 (7%)
Query: 31 AVCEGCQRPISDRFLMRVN-ESSWHEECLQCAACQQALTTSC--YFRDRKLYCKQDYQQL 87
++C GC I D++++RV+ + WH CL+CA C Q L SC + RD K YCK+DY +L
Sbjct: 15 SLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRDYIRL 74
Query: 88 FAAKCSGCMEKIAPTEFVMRALECVYHLGCFCCCVCERQLRKGDEFVLKEGQLLCKGDYE 147
+ KC+ C + +FVMRA VYH+ CF C C RQL GDEF L+E L C+ D+
Sbjct: 75 YGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDGLFCRADH- 133
Query: 148 KEKDLLSSVSPDESDSVKSEDEDGDMKPAKG--QGSQSKGSGDDGKDPRRPKRPRTILTT 205
D++ S D + ++ A Q K P + R RT+L
Sbjct: 134 ---DVVERASLGAGDPLSPLHPARPLQMAAEPISARQPALRPHVHKQPEKTTRVRTVLNE 190
Query: 206 QQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRHQQQQEQQ 265
+Q + + + +P ++E L TGLS RV++VWFQN+R K KK + +Q Q+QQ
Sbjct: 191 KQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRSIMMKQLQQQQ 250
Query: 266 NSQRLGQEVLSSRMEGMMASYTPLAPPQQQIVAMEQSPYGSSDPFQQGLTPPQMPGND-S 324
+ + + ++GM + A P++ ++ +P Q PP +D +
Sbjct: 251 PNDK-------TNIQGMTGTPMVAASPERHDGGLQANPVE-----VQSYQPPWKVLSDFA 298
Query: 325 IFHDIDSDT--SLTSLSDCFLGSSDVGSLQARVGNPI 359
+ DID L + S+ GS+ GS A + + +
Sbjct: 299 LQSDIDQPAFQQLVNFSEGGPGSNSTGSEVASMSSQL 335
>gi|50083287 LIM homeobox 8 [Homo sapiens]
Length = 356
Score = 165 bits (418), Expect = 5e-41
Identities = 92/245 (37%), Positives = 132/245 (53%), Gaps = 18/245 (7%)
Query: 12 LRPGPATLGVLLGSDCPH-PAVCEGCQRPISDRFLMRVNESSWHEECLQCAACQQALT-- 68
L P + + GS CP VC C I D++L++VN+ WH CL C+ C+ +L
Sbjct: 53 LSPSSSPRSMASGSGCPPGKCVCNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRH 112
Query: 69 TSCYFRDRKLYCKQDYQQLFAAKCSGCMEKIAPTEFVMRALECVYHLGCFCCCVCERQLR 128
TSCY +D+ ++CK DY + + +CS C I T++V RA VYHL CF C C+RQL
Sbjct: 113 TSCYIKDKDIFCKLDYFRRYGTRCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLS 172
Query: 129 KGDEFVLKEGQLLCKGDYEKEKDLLSSVSPDESDSVKSEDEDGDMKPAKGQGSQSKGSGD 188
G+EF L E ++LC+ Y+ D++K E E+G+ +G + +
Sbjct: 173 TGEEFALVEEKVLCRVHYD-----------CMLDNLKREVENGNGISVEG----ALLTEQ 217
Query: 189 DGKDPRRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQR 248
D P+ KR RT T Q + +A F + P + + LA TGLS RV+QVWFQN R
Sbjct: 218 DVNHPKPAKRARTSFTADQLQVMQAQFAQDNNPDAQTLQKLAERTGLSRRVIQVWFQNCR 277
Query: 249 AKMKK 253
A+ KK
Sbjct: 278 ARHKK 282
>gi|134284361 LIM homeobox protein 6 isoform 2 [Homo sapiens]
Length = 377
Score = 159 bits (401), Expect = 5e-39
Identities = 99/292 (33%), Positives = 149/292 (51%), Gaps = 28/292 (9%)
Query: 32 VCEGCQRPISDRFLMRVNESSWHEECLQCAACQQALT--TSCYFRDRKLYCKQDYQQLFA 89
+C C I DR+L++VN WH CL+C+ C+ +L SCY ++++++CK DY F
Sbjct: 98 ICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSRFG 157
Query: 90 AKCSGCMEKIAPTEFVMRALECVYHLGCFCCCVCERQLRKGDEFVLKEGQLLCKGDYEKE 149
KC+ C +I +++V RA YHL CF C C+RQL G+EF L E ++LC+ Y+
Sbjct: 158 TKCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYD-- 215
Query: 150 KDLLSSVSPDESDSVKSEDEDGDMKPAKGQGSQSKGSGDDGKDPRRPKRPRTILTTQQRR 209
+++K E+G+ +G + S P+ KR RT T +Q +
Sbjct: 216 ---------TMIENLKRAAENGNGLTLEGAVPSEQDS-----QPKPAKRARTSFTAEQLQ 261
Query: 210 AFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRHQQQQEQQNSQR 269
+A F + P + + LA TGLS RV+QVWFQN RA+ KK +H R
Sbjct: 262 VMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKKHTPQHPVPPSGAPPSR 321
Query: 270 LGQEVLSSRMEGMMASYTPLAPPQQ-QIVAMEQSPYGSSDPFQQGLTPPQMP 320
L LS + YTP + P++ ++V + Y S PF LT P +P
Sbjct: 322 L-PSALSDDIH-----YTPFSSPERARMVTLH--GYIESHPFSV-LTLPALP 364
>gi|134284359 LIM homeobox protein 6 isoform 1 [Homo sapiens]
Length = 392
Score = 156 bits (394), Expect = 3e-38
Identities = 90/265 (33%), Positives = 136/265 (51%), Gaps = 24/265 (9%)
Query: 32 VCEGCQRPISDRFLMRVNESSWHEECLQCAACQQALT--TSCYFRDRKLYCKQDYQQLFA 89
+C C I DR+L++VN WH CL+C+ C+ +L SCY ++++++CK DY F
Sbjct: 98 ICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSRFG 157
Query: 90 AKCSGCMEKIAPTEFVMRALECVYHLGCFCCCVCERQLRKGDEFVLKEGQLLCKGDYEKE 149
KC+ C +I +++V RA YHL CF C C+RQL G+EF L E ++LC+ Y+
Sbjct: 158 TKCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYD-- 215
Query: 150 KDLLSSVSPDESDSVKSEDEDGDMKPAKGQGSQSKGSGDDGKDPRRPKRPRTILTTQQRR 209
+++K E+G+ +G + S P+ KR RT T +Q +
Sbjct: 216 ---------TMIENLKRAAENGNGLTLEGAVPSEQDS-----QPKPAKRARTSFTAEQLQ 261
Query: 210 AFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRHQQQQEQQNSQR 269
+A F + P + + LA TGLS RV+QVWFQN RA+ KK +H R
Sbjct: 262 VMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKKHTPQHPVPPSGAPPSR 321
Query: 270 LGQEVLSSRMEGMMASYTPLAPPQQ 294
L LS + YTP + P++
Sbjct: 322 L-PSALSDDIH-----YTPFSSPER 340
>gi|33569216 LIM homeobox 9 isoform 1 [Homo sapiens]
Length = 397
Score = 144 bits (362), Expect = 2e-34
Identities = 85/266 (31%), Positives = 127/266 (47%), Gaps = 39/266 (14%)
Query: 30 PAVCEGCQRPISDRFLMRVNESSWHEECLQCAACQQALTT--SCYFRDRKLYCKQDYQQL 87
PA+C GC ISDR+ + + WH CL+C C+ AL + +C+ +D +YCK+DY +
Sbjct: 68 PALCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRR 127
Query: 88 FAA-KCSGCMEKIAPTEFVMRALECVYHLGCFCCCVCERQLRKGDEFVLKEGQLLCKGDY 146
F+ +C+ C I+ +E VMRA + VYHL CF C C + L GD F +K+ + C+ +
Sbjct: 128 FSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHF 187
Query: 147 EKEKDLLSSVSPDESDSVKSEDEDGDMKPA--KGQGSQSKGSGDDGKDP----------- 193
E LL P + + + G + G G+ KG K P
Sbjct: 188 E---TLLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNYNS 244
Query: 194 --------------------RRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAET 233
++ KR RT Q R K+ F ++ P K + LA +T
Sbjct: 245 GCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKT 304
Query: 234 GLSVRVVQVWFQNQRAKMKKLARRHQ 259
GL+ RV+QVWFQN RAK ++ R +
Sbjct: 305 GLTKRVLQVWFQNARAKFRRNLLRQE 330
>gi|62241033 LIM homeobox 9 isoform 2 [Homo sapiens]
Length = 388
Score = 144 bits (362), Expect = 2e-34
Identities = 85/266 (31%), Positives = 127/266 (47%), Gaps = 39/266 (14%)
Query: 30 PAVCEGCQRPISDRFLMRVNESSWHEECLQCAACQQALTT--SCYFRDRKLYCKQDYQQL 87
PA+C GC ISDR+ + + WH CL+C C+ AL + +C+ +D +YCK+DY +
Sbjct: 59 PALCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRR 118
Query: 88 FAA-KCSGCMEKIAPTEFVMRALECVYHLGCFCCCVCERQLRKGDEFVLKEGQLLCKGDY 146
F+ +C+ C I+ +E VMRA + VYHL CF C C + L GD F +K+ + C+ +
Sbjct: 119 FSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHF 178
Query: 147 EKEKDLLSSVSPDESDSVKSEDEDGDMKPA--KGQGSQSKGSGDDGKDP----------- 193
E LL P + + + G + G G+ KG K P
Sbjct: 179 E---TLLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNYNS 235
Query: 194 --------------------RRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAET 233
++ KR RT Q R K+ F ++ P K + LA +T
Sbjct: 236 GCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKT 295
Query: 234 GLSVRVVQVWFQNQRAKMKKLARRHQ 259
GL+ RV+QVWFQN RAK ++ R +
Sbjct: 296 GLTKRVLQVWFQNARAKFRRNLLRQE 321
>gi|41281895 LIM homeobox transcription factor 1, alpha isoform b
[Homo sapiens]
Length = 133
Score = 142 bits (358), Expect = 5e-34
Identities = 82/135 (60%), Positives = 100/135 (74%), Gaps = 15/135 (11%)
Query: 251 MKKLARRHQQQQE-QQNSQRLGQEVL----SSRMEGMMASYTPLAPPQQQIVAMEQSPYG 305
MKKLARR QQQQ+ QQN+QRL S+ MEG+M YT L PQQ ++A+EQS Y
Sbjct: 1 MKKLARRQQQQQQDQQNTQRLSSAQTNGGGSAGMEGIMNPYTALPTPQQ-LLAIEQSVY- 58
Query: 306 SSDPFQQGLTPPQMPGN-------DSIFHDIDSD-TSLTSLSDCFLGSSDVGSLQARVGN 357
SSDPF+QGLTPPQMPG+ + +FHD+DSD TSL++L DCFL +S+ G LQ+RVGN
Sbjct: 59 SSDPFRQGLTPPQMPGDHMHPYGAEPLFHDLDSDDTSLSNLGDCFLATSEAGPLQSRVGN 118
Query: 358 PIDRLYSMQSSYFAS 372
PID LYSMQ+SYF S
Sbjct: 119 PIDHLYSMQNSYFTS 133
>gi|30795196 LIM homeobox protein 2 [Homo sapiens]
Length = 406
Score = 130 bits (328), Expect = 1e-30
Identities = 104/372 (27%), Positives = 157/372 (42%), Gaps = 81/372 (21%)
Query: 31 AVCEGCQRPISDRFLMRVNESSWHEECLQCAACQQALTT--SCYFRDRKLYCKQDYQQLF 88
A+C GC ISDR+ + + WH CL+C C+ L + +C+ +D +YCK+DY + F
Sbjct: 51 ALCAGCGGKISDRYYLLAVDKQWHMRCLKCCECKLNLESELTCFSKDGSIYCKEDYYRRF 110
Query: 89 AA-KCSGCMEKIAPTEFVMRALECVYHLGCFCCCVCERQLRKGDEFVLKEGQLLCKGDYE 147
+ +C+ C I+ +E VMRA + VYHL CF C C + L GD F +K+ + C+ +E
Sbjct: 111 SVQRCARCHLGISASEMVMRARDLVYHLNCFTCTTCNKMLTTGDHFGMKDSLVYCRLHFE 170
Query: 148 KEKDLLSSVSP---DESDSVKSEDEDGDMKPA---------------KGQGSQSKGSGDD 189
LL P + +D + K A G G+ KG
Sbjct: 171 A---LLQGEYPAHFNHADVAAAAAAAAAAKSAGLGAAGANPLGLPYYNGVGTVQKGRPRK 227
Query: 190 GKDP--------------------------------RRPKRPRTILTTQQRRAFKASFEV 217
K P ++ KR RT Q R K+ F +
Sbjct: 228 RKSPGPGADLAAYNAALSCNENDAEHLDRDQPYPSSQKTKRMRTSFKHHQLRTMKSYFAI 287
Query: 218 SSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRHQQQQEQQNSQRLGQEVLSS 277
+ P K + LA +TGL+ RV+QVWFQN RAK RR+ +QE +
Sbjct: 288 NHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKF----RRNLLRQENTG--------VDK 335
Query: 278 RMEGMMASYTPLAPPQQQIVAMEQSPYGSSDPFQQGLTPPQMPGNDSIFHDI-------- 329
+ + + TP + P ++ SP S+ LT P +P S+ +
Sbjct: 336 STDAALQTGTP-SGPASELSNASLSP-SSTPTTLTDLTSPTLPTVTSVLTSVPGNLEGHE 393
Query: 330 ---DSDTSLTSL 338
S T+LT+L
Sbjct: 394 PHSPSQTTLTNL 405
>gi|75677381 LIM homeobox transcription factor 1, alpha isoform c
[Homo sapiens]
Length = 100
Score = 120 bits (300), Expect = 3e-27
Identities = 64/102 (62%), Positives = 79/102 (77%), Gaps = 10/102 (9%)
Query: 279 MEGMMASYTPLAPPQQQIVAMEQSPYGSSDPFQQGLTPPQMPGN-------DSIFHDIDS 331
MEG+M YT L PQQ ++A+EQS Y SSDPF+QGLTPPQMPG+ + +FHD+DS
Sbjct: 1 MEGIMNPYTALPTPQQ-LLAIEQSVY-SSDPFRQGLTPPQMPGDHMHPYGAEPLFHDLDS 58
Query: 332 D-TSLTSLSDCFLGSSDVGSLQARVGNPIDRLYSMQSSYFAS 372
D TSL++L DCFL +S+ G LQ+RVGNPID LYSMQ+SYF S
Sbjct: 59 DDTSLSNLGDCFLATSEAGPLQSRVGNPIDHLYSMQNSYFTS 100
>gi|21361802 LIM domain only 3 [Homo sapiens]
Length = 145
Score = 109 bits (272), Expect = 5e-24
Identities = 50/124 (40%), Positives = 73/124 (58%), Gaps = 5/124 (4%)
Query: 30 PAVCEGCQRPISDRFLMRVNESSWHEECLQCAACQQALT---TSCYFRDRKLYCKQDYQQ 86
P C GC R I DR+L++ + WHE+CL+CA C L ++ Y + + C++DY +
Sbjct: 10 PKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLR 69
Query: 87 LFAA--KCSGCMEKIAPTEFVMRALECVYHLGCFCCCVCERQLRKGDEFVLKEGQLLCKG 144
LF C+ C + I E VMRA + VYHL CF C +C ++ GD+F LK +LC+
Sbjct: 70 LFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQRFCVGDKFFLKNNMILCQT 129
Query: 145 DYEK 148
DYE+
Sbjct: 130 DYEE 133
>gi|47778935 LIM domain only 3 [Homo sapiens]
Length = 145
Score = 109 bits (272), Expect = 5e-24
Identities = 50/124 (40%), Positives = 73/124 (58%), Gaps = 5/124 (4%)
Query: 30 PAVCEGCQRPISDRFLMRVNESSWHEECLQCAACQQALT---TSCYFRDRKLYCKQDYQQ 86
P C GC R I DR+L++ + WHE+CL+CA C L ++ Y + + C++DY +
Sbjct: 10 PKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLR 69
Query: 87 LFAA--KCSGCMEKIAPTEFVMRALECVYHLGCFCCCVCERQLRKGDEFVLKEGQLLCKG 144
LF C+ C + I E VMRA + VYHL CF C +C ++ GD+F LK +LC+
Sbjct: 70 LFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQRFCVGDKFFLKNNMILCQT 129
Query: 145 DYEK 148
DYE+
Sbjct: 130 DYEE 133
>gi|4505005 LIM domain only 1 [Homo sapiens]
Length = 156
Score = 107 bits (268), Expect = 1e-23
Identities = 49/121 (40%), Positives = 72/121 (59%), Gaps = 5/121 (4%)
Query: 33 CEGCQRPISDRFLMRVNESSWHEECLQCAACQQALT---TSCYFRDRKLYCKQDYQQLFA 89
C GC R I DR+L++ + WHE+CL+CA C L ++ Y + + C++DY +LF
Sbjct: 24 CAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFG 83
Query: 90 A--KCSGCMEKIAPTEFVMRALECVYHLGCFCCCVCERQLRKGDEFVLKEGQLLCKGDYE 147
C+ C + I E VMRA + VYHL CF C +C ++ GD+F LK +LC+ DYE
Sbjct: 84 TTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRFCVGDKFFLKNNMILCQMDYE 143
Query: 148 K 148
+
Sbjct: 144 E 144
>gi|5803072 LIM domain only 4 [Homo sapiens]
Length = 165
Score = 105 bits (261), Expect = 9e-23
Identities = 56/138 (40%), Positives = 71/138 (51%), Gaps = 11/138 (7%)
Query: 13 RPGPATLGVLLGSDCPHPAVCEGCQRPISDRFLMRVNESSWHEECLQCAACQQALT---T 69
+P P T G L C GC I+DRFL+ +S WH CL+C+ CQ L T
Sbjct: 9 QPPPVTAGSLSWKRCA------GCGGKIADRFLLYAMDSYWHSRCLKCSCCQAQLGDIGT 62
Query: 70 SCYFRDRKLYCKQDYQQLF--AAKCSGCMEKIAPTEFVMRALECVYHLGCFCCCVCERQL 127
SCY + + C+ DY +LF + CS C + I +E VMRA VYHL CF C C +L
Sbjct: 63 SCYTKSGMILCRNDYIRLFGNSGACSACGQSIPASELVMRAQGNVYHLKCFTCSTCRNRL 122
Query: 128 RKGDEFVLKEGQLLCKGD 145
GD F G L C+ D
Sbjct: 123 VPGDRFHYINGSLFCEHD 140
Score = 43.1 bits (100), Expect = 4e-04
Identities = 21/57 (36%), Positives = 31/57 (54%), Gaps = 2/57 (3%)
Query: 91 KCSGCMEKIAPTEFVMRALECVYHLGCFCCCVCERQLRK-GDEFVLKEGQLLCKGDY 146
+C+GC KIA F++ A++ +H C C C+ QL G K G +LC+ DY
Sbjct: 22 RCAGCGGKIAD-RFLLYAMDSYWHSRCLKCSCCQAQLGDIGTSCYTKSGMILCRNDY 77
>gi|214832219 LIM domain only 2 isoform 2 [Homo sapiens]
Length = 158
Score = 89.4 bits (220), Expect = 5e-18
Identities = 44/129 (34%), Positives = 67/129 (51%), Gaps = 6/129 (4%)
Query: 28 PHPAVCEGCQRPISDRFLMRVNESSWHEECLQCAACQQALTT---SCYFRDRKLYCKQDY 84
P C GCQ+ I DR+ ++ + WHE+CL C C L Y++ + C++DY
Sbjct: 25 PSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLSCDLCGCRLGEVGRRLYYKLGRKLCRRDY 84
Query: 85 QQLFAAK--CSGCMEKIAPTEFVMRALECVYHLGCFCCCVCERQLRKGDEFVLKEGQLLC 142
+LF C+ C ++I E MR + VYHL CF C C++ GD ++L ++C
Sbjct: 85 LRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECFKCAACQKHFCVGDRYLLINSDIVC 144
Query: 143 KGD-YEKEK 150
+ D YE K
Sbjct: 145 EQDIYEWTK 153
>gi|214832121 LIM domain only 2 isoform 2 [Homo sapiens]
Length = 158
Score = 89.4 bits (220), Expect = 5e-18
Identities = 44/129 (34%), Positives = 67/129 (51%), Gaps = 6/129 (4%)
Query: 28 PHPAVCEGCQRPISDRFLMRVNESSWHEECLQCAACQQALTT---SCYFRDRKLYCKQDY 84
P C GCQ+ I DR+ ++ + WHE+CL C C L Y++ + C++DY
Sbjct: 25 PSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLSCDLCGCRLGEVGRRLYYKLGRKLCRRDY 84
Query: 85 QQLFAAK--CSGCMEKIAPTEFVMRALECVYHLGCFCCCVCERQLRKGDEFVLKEGQLLC 142
+LF C+ C ++I E MR + VYHL CF C C++ GD ++L ++C
Sbjct: 85 LRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECFKCAACQKHFCVGDRYLLINSDIVC 144
Query: 143 KGD-YEKEK 150
+ D YE K
Sbjct: 145 EQDIYEWTK 153
>gi|214832074 LIM domain only 2 isoform 1 [Homo sapiens]
Length = 227
Score = 89.4 bits (220), Expect = 5e-18
Identities = 44/129 (34%), Positives = 67/129 (51%), Gaps = 6/129 (4%)
Query: 28 PHPAVCEGCQRPISDRFLMRVNESSWHEECLQCAACQQALTT---SCYFRDRKLYCKQDY 84
P C GCQ+ I DR+ ++ + WHE+CL C C L Y++ + C++DY
Sbjct: 94 PSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLSCDLCGCRLGEVGRRLYYKLGRKLCRRDY 153
Query: 85 QQLFAAK--CSGCMEKIAPTEFVMRALECVYHLGCFCCCVCERQLRKGDEFVLKEGQLLC 142
+LF C+ C ++I E MR + VYHL CF C C++ GD ++L ++C
Sbjct: 154 LRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECFKCAACQKHFCVGDRYLLINSDIVC 213
Query: 143 KGD-YEKEK 150
+ D YE K
Sbjct: 214 EQDIYEWTK 222
>gi|4505001 LIM domain kinase 1 [Homo sapiens]
Length = 647
Score = 80.9 bits (198), Expect = 2e-15
Identities = 46/143 (32%), Positives = 68/143 (47%), Gaps = 7/143 (4%)
Query: 24 GSDCPHPAVCEGCQRPISDRFLMRVNESSWHEECLQCAACQQALTTSCYFRDRKLYCKQD 83
GS+ P VC C + I D ++ + WH +C +C C +L+ Y +D +L+CK+D
Sbjct: 19 GSELP---VCASCGQRIYDGQYLQALNADWHADCFRCCDCSASLSHQYYEKDGQLFCKKD 75
Query: 84 YQQLFAAKCSGCMEKIAPTEFVMRALECVYHLGCFCCCVCERQLRKGDEFVLKE-GQLLC 142
Y + C GC E+I VM A E YH CF C C + GD + L E +L C
Sbjct: 76 YWARYGESCHGCSEQIT-KGLVMVAGELKYHPECFICLTCGTFIGDGDTYTLVEHSKLYC 134
Query: 143 KGDYEKE--KDLLSSVSPDESDS 163
Y + ++ + PD S
Sbjct: 135 GHCYYQTVVTPVIEQILPDSPGS 157
>gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens]
Length = 423
Score = 77.0 bits (188), Expect = 2e-14
Identities = 37/119 (31%), Positives = 63/119 (52%), Gaps = 3/119 (2%)
Query: 26 DCPHPAVCEGCQRPISDRFLMRVNESSWHEECLQCAACQQALTTSCYFRDRKL-YCKQDY 84
D + C C++ I+ +M + +WH C CAAC+ + ++ + + YC++DY
Sbjct: 300 DVRYAPSCAKCKKKITGE-IMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDY 358
Query: 85 QQLFAAKCSGCMEKIAPTEFVMRALECVYHLGCFCCCVCERQLRKGDEFVLKEGQLLCK 143
+++F KC GC KI + + AL +H CF C +C+ L +G F K+ + LCK
Sbjct: 359 EKMFGTKCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINL-EGKTFYSKKDRPLCK 416
Score = 71.6 bits (174), Expect = 1e-12
Identities = 39/126 (30%), Positives = 65/126 (51%), Gaps = 5/126 (3%)
Query: 24 GSDCPHPAVCEGCQRPISDRFLMRVNESSWHEECLQCAACQQALTTSCYFRDR-KLYCKQ 82
GS+ VC C + I R+L+ + + +H E C+ C + L +F ++ ++C
Sbjct: 239 GSNNGKTPVCHQCHKVIRGRYLVALGHA-YHPEEFVCSQCGKVLEEGGFFEEKGAIFCPP 297
Query: 83 DYQQLFAAKCSGCMEKIAPTEFVMRALECVYHLGCFCCCVCERQLRKGDEFVLKEGQLLC 142
Y +A C+ C +KI T +M AL+ +H+ CF C C+ +R F ++EG C
Sbjct: 298 CYDVRYAPSCAKCKKKI--TGEIMHALKMTWHVHCFTCAACKTPIRNR-AFYMEEGVPYC 354
Query: 143 KGDYEK 148
+ DYEK
Sbjct: 355 ERDYEK 360
>gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens]
Length = 457
Score = 77.0 bits (188), Expect = 2e-14
Identities = 37/119 (31%), Positives = 63/119 (52%), Gaps = 3/119 (2%)
Query: 26 DCPHPAVCEGCQRPISDRFLMRVNESSWHEECLQCAACQQALTTSCYFRDRKL-YCKQDY 84
D + C C++ I+ +M + +WH C CAAC+ + ++ + + YC++DY
Sbjct: 334 DVRYAPSCAKCKKKITGE-IMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDY 392
Query: 85 QQLFAAKCSGCMEKIAPTEFVMRALECVYHLGCFCCCVCERQLRKGDEFVLKEGQLLCK 143
+++F KC GC KI + + AL +H CF C +C+ L +G F K+ + LCK
Sbjct: 393 EKMFGTKCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINL-EGKTFYSKKDRPLCK 450
Score = 71.6 bits (174), Expect = 1e-12
Identities = 39/126 (30%), Positives = 65/126 (51%), Gaps = 5/126 (3%)
Query: 24 GSDCPHPAVCEGCQRPISDRFLMRVNESSWHEECLQCAACQQALTTSCYFRDR-KLYCKQ 82
GS+ VC C + I R+L+ + + +H E C+ C + L +F ++ ++C
Sbjct: 273 GSNNGKTPVCHQCHKVIRGRYLVALGHA-YHPEEFVCSQCGKVLEEGGFFEEKGAIFCPP 331
Query: 83 DYQQLFAAKCSGCMEKIAPTEFVMRALECVYHLGCFCCCVCERQLRKGDEFVLKEGQLLC 142
Y +A C+ C +KI T +M AL+ +H+ CF C C+ +R F ++EG C
Sbjct: 332 CYDVRYAPSCAKCKKKI--TGEIMHALKMTWHVHCFTCAACKTPIRNR-AFYMEEGVPYC 388
Query: 143 KGDYEK 148
+ DYEK
Sbjct: 389 ERDYEK 394
>gi|5031869 LIM domain kinase 2 isoform 2a [Homo sapiens]
Length = 638
Score = 73.9 bits (180), Expect = 2e-13
Identities = 44/136 (32%), Positives = 61/136 (44%), Gaps = 3/136 (2%)
Query: 33 CEGCQRPIS-DRFLMRVNESSWHEECLQCAACQQALTTSCYFRDRKLYCKQDYQQLFAAK 91
C GC I+ + R +WH C +C+ CQ +LT Y +D KLYC +DY F
Sbjct: 12 CPGCGDHIAPSQIWYRTVNETWHGSCFRCSECQDSLTNWYYEKDGKLYCPKDYWGKFGEF 71
Query: 92 CSGCMEKIAPTEFVMRALECVYHLGCFCCCVCERQLRKGDEFVLKEGQLLCKGDYEKEKD 151
C GC + T M A E YH CF C C+ + GD + L + L G E
Sbjct: 72 CHGC--SLLMTGPFMVAGEFKYHPECFACMSCKVIIEDGDAYALVQHATLYCGKCHNEVV 129
Query: 152 LLSSVSPDESDSVKSE 167
L ++SV+ +
Sbjct: 130 LAPMFERLSTESVQEQ 145
Score = 41.2 bits (95), Expect = 0.002
Identities = 19/56 (33%), Positives = 30/56 (53%), Gaps = 2/56 (3%)
Query: 91 KCSGCMEKIAPTEFVMRALECVYHLGCFCCCVCERQLRKGDEFVLKEGQLLCKGDY 146
+C GC + IAP++ R + +H CF C C+ L + + K+G+L C DY
Sbjct: 11 RCPGCGDHIAPSQIWYRTVNETWHGSCFRCSECQDSLT--NWYYEKDGKLYCPKDY 64
>gi|51173713 actin-binding LIM protein 1 isoform b [Homo sapiens]
Length = 718
Score = 73.2 bits (178), Expect = 4e-13
Identities = 41/132 (31%), Positives = 62/132 (46%), Gaps = 5/132 (3%)
Query: 33 CEGCQRPISDRFLMRVNESSWHEECLQCAACQQALTTSCYFRDRKLYCKQDYQQLFAAKC 92
C GC R I + + + WH C +C +C + LT +D YC++DYQ LF KC
Sbjct: 166 CAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGEYISKDGAPYCEKDYQGLFGVKC 225
Query: 93 SGCMEKIAPTEFVMRALECVYHLGCFCCCVCERQLRKGDEFVLKEGQLL---CKGDYEKE 149
C + I T V+ A + YH C C C + +G+E L+ + CK + E
Sbjct: 226 EACHQFI--TGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTE 283
Query: 150 KDLLSSVSPDES 161
+ L + + ES
Sbjct: 284 EKLRPTRTSSES 295
Score = 64.3 bits (155), Expect = 2e-10
Identities = 34/112 (30%), Positives = 49/112 (43%), Gaps = 4/112 (3%)
Query: 33 CEGCQRPISDRFLMRVNESSWHEECLQCAACQQALTTSCYF-RDRKLYCKQDYQQLFAAK 91
C C P L RV +H +C C C L +F ++ + C DYQ+++ +
Sbjct: 39 CHKCGEPCKGEVL-RVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTR 97
Query: 92 CSGCMEKIAPTEFVMRALECVYHLGCFCCCVCERQLRKGDEFVLKEGQLLCK 143
C GC E + V+ AL YH CF C +C+R GD LC+
Sbjct: 98 CHGCGEFVEGE--VVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQ 147
Score = 36.2 bits (82), Expect = 0.049
Identities = 17/44 (38%), Positives = 25/44 (56%), Gaps = 1/44 (2%)
Query: 105 VMRALECVYHLGCFCCCVCERQLRKGDEFVLKEGQLLCKGDYEK 148
V+R +H+ CF C VC L +G F +K G+ LC DY++
Sbjct: 50 VLRVQTKHFHIKCFTCKVCGCDLAQGG-FFIKNGEYLCTLDYQR 92
>gi|51173711 actin-binding LIM protein 1 isoform a [Homo sapiens]
Length = 778
Score = 73.2 bits (178), Expect = 4e-13
Identities = 41/132 (31%), Positives = 62/132 (46%), Gaps = 5/132 (3%)
Query: 33 CEGCQRPISDRFLMRVNESSWHEECLQCAACQQALTTSCYFRDRKLYCKQDYQQLFAAKC 92
C GC R I + + + WH C +C +C + LT +D YC++DYQ LF KC
Sbjct: 226 CAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGEYISKDGAPYCEKDYQGLFGVKC 285
Query: 93 SGCMEKIAPTEFVMRALECVYHLGCFCCCVCERQLRKGDEFVLKEGQLL---CKGDYEKE 149
C + I T V+ A + YH C C C + +G+E L+ + CK + E
Sbjct: 286 EACHQFI--TGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTE 343
Query: 150 KDLLSSVSPDES 161
+ L + + ES
Sbjct: 344 EKLRPTRTSSES 355
Score = 64.3 bits (155), Expect = 2e-10
Identities = 34/112 (30%), Positives = 49/112 (43%), Gaps = 4/112 (3%)
Query: 33 CEGCQRPISDRFLMRVNESSWHEECLQCAACQQALTTSCYF-RDRKLYCKQDYQQLFAAK 91
C C P L RV +H +C C C L +F ++ + C DYQ+++ +
Sbjct: 99 CHKCGEPCKGEVL-RVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTR 157
Query: 92 CSGCMEKIAPTEFVMRALECVYHLGCFCCCVCERQLRKGDEFVLKEGQLLCK 143
C GC E + V+ AL YH CF C +C+R GD LC+
Sbjct: 158 CHGCGEFVEGE--VVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQ 207
Score = 36.2 bits (82), Expect = 0.049
Identities = 17/44 (38%), Positives = 25/44 (56%), Gaps = 1/44 (2%)
Query: 105 VMRALECVYHLGCFCCCVCERQLRKGDEFVLKEGQLLCKGDYEK 148
V+R +H+ CF C VC L +G F +K G+ LC DY++
Sbjct: 110 VLRVQTKHFHIKCFTCKVCGCDLAQGG-FFIKNGEYLCTLDYQR 152
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.132 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,546,060
Number of Sequences: 37866
Number of extensions: 761027
Number of successful extensions: 6384
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 377
Number of HSP's successfully gapped in prelim test: 157
Number of HSP's that attempted gapping in prelim test: 4609
Number of HSP's gapped (non-prelim): 1119
length of query: 372
length of database: 18,247,518
effective HSP length: 104
effective length of query: 268
effective length of database: 14,309,454
effective search space: 3834933672
effective search space used: 3834933672
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.