Search of human proteins with 4503131

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4503131 catenin (cadherin-associated protein), beta 1, 88kDa
[Homo sapiens]
         (781 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|148227672 catenin (cadherin-associated protein), beta 1, 88kD...  1551   0.0  
gi|148233338 catenin (cadherin-associated protein), beta 1, 88kD...  1551   0.0  
gi|4503131 catenin (cadherin-associated protein), beta 1, 88kDa ...  1551   0.0  
gi|4504811 junction plakoglobin [Homo sapiens]                        952   0.0  
gi|12056468 junction plakoglobin [Homo sapiens]                       952   0.0  
gi|31657114 armadillo repeat containing 4 [Homo sapiens]               72   2e-12
gi|189409124 armadillo repeat containing 3 [Homo sapiens]              67   6e-11
gi|224589129 karyopherin 7 [Homo sapiens]                              54   4e-07
gi|4504897 karyopherin alpha 2 [Homo sapiens]                          54   4e-07
gi|4502247 armadillo repeat protein [Homo sapiens]                     54   4e-07
gi|32526896 armadillo repeat containing 8 isoform 2 [Homo sapiens]     50   6e-06
gi|11034811 catenin (cadherin-associated protein), delta 2 (neur...    49   1e-05
gi|189011568 adenomatous polyposis coli [Homo sapiens]                 49   2e-05
gi|189011566 adenomatous polyposis coli [Homo sapiens]                 49   2e-05
gi|53759122 adenomatous polyposis coli [Homo sapiens]                  49   2e-05
gi|146231975 catenin, delta 1 isoform 3A [Homo sapiens]                47   7e-05
gi|146231948 catenin, delta 1 isoform 3A [Homo sapiens]                47   7e-05
gi|146231994 catenin, delta 1 isoform 3A [Homo sapiens]                47   7e-05
gi|146231977 catenin, delta 1 isoform 3AC [Homo sapiens]               47   7e-05
gi|146231946 catenin, delta 1 isoform 3B [Homo sapiens]                47   7e-05
gi|146231991 catenin, delta 1 isoform 3AB [Homo sapiens]               47   7e-05
gi|146231970 catenin, delta 1 isoform 3ABC [Homo sapiens]              47   7e-05
gi|146231942 catenin, delta 1 isoform 1A [Homo sapiens]                47   7e-05
gi|146231968 catenin, delta 1 isoform 1A [Homo sapiens]                47   7e-05
gi|146231938 catenin, delta 1 isoform 1A [Homo sapiens]                47   7e-05
gi|10835010 catenin, delta 1 isoform 1B [Homo sapiens]                 47   7e-05
gi|146231962 catenin, delta 1 isoform 1AB [Homo sapiens]               47   7e-05
gi|146231940 catenin, delta 1 isoform 1ABC [Homo sapiens]              47   7e-05
gi|91206450 ankyrin and armadillo repeat containing [Homo sapiens]     47   9e-05
gi|53829376 plakophilin 4 isoform b [Homo sapiens]                     42   0.002

>gi|148227672 catenin (cadherin-associated protein), beta 1, 88kDa
           [Homo sapiens]
          Length = 781

 Score = 1551 bits (4016), Expect = 0.0
 Identities = 781/781 (100%), Positives = 781/781 (100%)

Query: 1   MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTS 60
           MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTS
Sbjct: 1   MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTS 60

Query: 61  QVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPT 120
           QVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPT
Sbjct: 61  QVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPT 120

Query: 121 NVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSK 180
           NVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSK
Sbjct: 121 NVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSK 180

Query: 181 KEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPAL 240
           KEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPAL
Sbjct: 181 KEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPAL 240

Query: 241 VKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDC 300
           VKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDC
Sbjct: 241 VKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDC 300

Query: 301 LQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEA 360
           LQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEA
Sbjct: 301 LQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEA 360

Query: 361 GGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCA 420
           GGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCA
Sbjct: 361 GGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCA 420

Query: 421 AGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEM 480
           AGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEM
Sbjct: 421 AGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEM 480

Query: 481 AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL 540
           AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL
Sbjct: 481 AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL 540

Query: 541 VRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFV 600
           VRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFV
Sbjct: 541 VRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFV 600

Query: 601 QLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLF 660
           QLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLF
Sbjct: 601 QLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLF 660

Query: 661 RMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEPLGYRQDDPSYRSFH 720
           RMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEPLGYRQDDPSYRSFH
Sbjct: 661 RMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEPLGYRQDDPSYRSFH 720

Query: 721 SGGYGQDALGMDPMMEHEMGGHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAWFDTD 780
           SGGYGQDALGMDPMMEHEMGGHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAWFDTD
Sbjct: 721 SGGYGQDALGMDPMMEHEMGGHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAWFDTD 780

Query: 781 L 781
           L
Sbjct: 781 L 781


>gi|148233338 catenin (cadherin-associated protein), beta 1, 88kDa
           [Homo sapiens]
          Length = 781

 Score = 1551 bits (4016), Expect = 0.0
 Identities = 781/781 (100%), Positives = 781/781 (100%)

Query: 1   MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTS 60
           MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTS
Sbjct: 1   MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTS 60

Query: 61  QVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPT 120
           QVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPT
Sbjct: 61  QVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPT 120

Query: 121 NVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSK 180
           NVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSK
Sbjct: 121 NVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSK 180

Query: 181 KEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPAL 240
           KEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPAL
Sbjct: 181 KEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPAL 240

Query: 241 VKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDC 300
           VKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDC
Sbjct: 241 VKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDC 300

Query: 301 LQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEA 360
           LQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEA
Sbjct: 301 LQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEA 360

Query: 361 GGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCA 420
           GGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCA
Sbjct: 361 GGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCA 420

Query: 421 AGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEM 480
           AGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEM
Sbjct: 421 AGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEM 480

Query: 481 AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL 540
           AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL
Sbjct: 481 AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL 540

Query: 541 VRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFV 600
           VRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFV
Sbjct: 541 VRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFV 600

Query: 601 QLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLF 660
           QLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLF
Sbjct: 601 QLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLF 660

Query: 661 RMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEPLGYRQDDPSYRSFH 720
           RMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEPLGYRQDDPSYRSFH
Sbjct: 661 RMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEPLGYRQDDPSYRSFH 720

Query: 721 SGGYGQDALGMDPMMEHEMGGHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAWFDTD 780
           SGGYGQDALGMDPMMEHEMGGHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAWFDTD
Sbjct: 721 SGGYGQDALGMDPMMEHEMGGHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAWFDTD 780

Query: 781 L 781
           L
Sbjct: 781 L 781


>gi|4503131 catenin (cadherin-associated protein), beta 1, 88kDa
           [Homo sapiens]
          Length = 781

 Score = 1551 bits (4016), Expect = 0.0
 Identities = 781/781 (100%), Positives = 781/781 (100%)

Query: 1   MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTS 60
           MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTS
Sbjct: 1   MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTS 60

Query: 61  QVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPT 120
           QVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPT
Sbjct: 61  QVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPT 120

Query: 121 NVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSK 180
           NVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSK
Sbjct: 121 NVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSK 180

Query: 181 KEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPAL 240
           KEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPAL
Sbjct: 181 KEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPAL 240

Query: 241 VKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDC 300
           VKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDC
Sbjct: 241 VKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDC 300

Query: 301 LQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEA 360
           LQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEA
Sbjct: 301 LQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEA 360

Query: 361 GGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCA 420
           GGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCA
Sbjct: 361 GGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCA 420

Query: 421 AGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEM 480
           AGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEM
Sbjct: 421 AGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEM 480

Query: 481 AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL 540
           AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL
Sbjct: 481 AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL 540

Query: 541 VRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFV 600
           VRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFV
Sbjct: 541 VRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFV 600

Query: 601 QLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLF 660
           QLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLF
Sbjct: 601 QLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLF 660

Query: 661 RMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEPLGYRQDDPSYRSFH 720
           RMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEPLGYRQDDPSYRSFH
Sbjct: 661 RMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEPLGYRQDDPSYRSFH 720

Query: 721 SGGYGQDALGMDPMMEHEMGGHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAWFDTD 780
           SGGYGQDALGMDPMMEHEMGGHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAWFDTD
Sbjct: 721 SGGYGQDALGMDPMMEHEMGGHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAWFDTD 780

Query: 781 L 781
           L
Sbjct: 781 L 781


>gi|4504811 junction plakoglobin [Homo sapiens]
          Length = 745

 Score =  952 bits (2462), Expect = 0.0
 Identities = 511/749 (68%), Positives = 585/749 (78%), Gaps = 19/749 (2%)

Query: 8   MELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTSQVLYEWE 67
           ME+   ME   K  V+ WQQ    DSGIHSGA T  PS+S KG  EE++    Q   +  
Sbjct: 1   MEVMNLMEQPIK--VTEWQQTYTYDSGIHSGANTCVPSVSSKGIMEEDEACGRQYTLKKT 58

Query: 68  QGFSQSFTQEQVADIDGQYAMT-RAQRVRAAMFPETLDEGMQIPSTQFDAAHPTNVQRLA 126
             ++Q     Q  D++ Q + T RA+RVR AM P    E   +          TN+QRLA
Sbjct: 59  TTYTQGVPPSQ-GDLEYQMSTTARAKRVREAMCPGVSGEDSSLLLATQVEGQATNLQRLA 117

Query: 127 EPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRH 186
           EPSQ+LK A+V+LINYQDDAELATRA+PELTKLLNDED VVV KAA++V+QLSKKEASR 
Sbjct: 118 EPSQLLKSAIVHLINYQDDAELATRALPELTKLLNDEDPVVVTKAAMIVNQLSKKEASRR 177

Query: 187 AIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGS 246
           A+M SPQ+V+A+VRTMQNT+D++TARCT   LHNLSHHREGLLAIFKSGGIPALV+ML S
Sbjct: 178 ALMGSPQLVAAVVRTMQNTSDLDTARCTTSILHNLSHHREGLLAIFKSGGIPALVRMLSS 237

Query: 247 PVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAY 306
           PV+SVLFYAITTLHNLLL+QEGAKMAVRLA GLQKMV LLNK N KFLAITTDCLQ+LAY
Sbjct: 238 PVESVLFYAITTLHNLLLYQEGAKMAVRLADGLQKMVPLLNKNNPKFLAITTDCLQLLAY 297

Query: 307 GNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQAL 366
           GNQESKLIILA+GGPQALV IMR Y+YEKLLWTTSRVLKVLSVC SNKPAIVEAGGMQAL
Sbjct: 298 GNQESKLIILANGGPQALVQIMRNYSYEKLLWTTSRVLKVLSVCPSNKPAIVEAGGMQAL 357

Query: 367 GLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSN 426
           G HLT  S RLVQNCLWTLRNLSD ATKQEG+E +L  LV  L  DD+NV+TCA G LSN
Sbjct: 358 GKHLTSNSPRLVQNCLWTLRNLSDVATKQEGLESVLKILVNQLSVDDVNVLTCATGTLSN 417

Query: 427 LTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVR 486
           LTCNN KNK +V Q  G+EAL+  +LRAGD++DITEPA+CALRHLTSRH EAEMAQN+VR
Sbjct: 418 LTCNNSKNKTLVTQNSGVEALIHAILRAGDKDDITEPAVCALRHLTSRHPEAEMAQNSVR 477

Query: 487 LHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQD 546
           L+YG+P +VKLL+ P+ WPL+KAT+GLIRNLALCPANHAPL+E   IPRLVQLLV+AHQD
Sbjct: 478 LNYGIPAIVKLLNQPNQWPLVKATIGLIRNLALCPANHAPLQEAAVIPRLVQLLVKAHQD 537

Query: 547 TQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSP 606
            QR  +  GTQQ + +GVRMEEIVEGCTGALHILARD  NR+ I  LNTIPLFVQLLYS 
Sbjct: 538 AQRHVA-AGTQQPYTDGVRMEEIVEGCTGALHILARDPMNRMEIFRLNTIPLFVQLLYSS 596

Query: 607 IENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLFRMSEDK 666
           +ENIQRVAAGVLCELAQDKEAA+AI+AEGA+APL ELLHSRNEG ATYAAAVLFR+SEDK
Sbjct: 597 VENIQRVAAGVLCELAQDKEAADAIDAEGASAPLMELLHSRNEGTATYAAAVLFRISEDK 656

Query: 667 PQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEPLGYRQDDPSYRSFHSGGYGQ 726
             DY+KR+SVELT+SLF+ +P AW E A   + I    EP G    D +YR  +S     
Sbjct: 657 NPDYRKRVSVELTNSLFKHDPAAW-EAAQSMIPI---NEPYG-DDMDATYRPMYSSDVPL 711

Query: 727 DALGMDPMMEHEMGGHHPGADYPVDGLPD 755
           D L M   M+          DYP+D   D
Sbjct: 712 DPLEMHMDMD---------GDYPIDTYSD 731


>gi|12056468 junction plakoglobin [Homo sapiens]
          Length = 745

 Score =  952 bits (2462), Expect = 0.0
 Identities = 511/749 (68%), Positives = 585/749 (78%), Gaps = 19/749 (2%)

Query: 8   MELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTSQVLYEWE 67
           ME+   ME   K  V+ WQQ    DSGIHSGA T  PS+S KG  EE++    Q   +  
Sbjct: 1   MEVMNLMEQPIK--VTEWQQTYTYDSGIHSGANTCVPSVSSKGIMEEDEACGRQYTLKKT 58

Query: 68  QGFSQSFTQEQVADIDGQYAMT-RAQRVRAAMFPETLDEGMQIPSTQFDAAHPTNVQRLA 126
             ++Q     Q  D++ Q + T RA+RVR AM P    E   +          TN+QRLA
Sbjct: 59  TTYTQGVPPSQ-GDLEYQMSTTARAKRVREAMCPGVSGEDSSLLLATQVEGQATNLQRLA 117

Query: 127 EPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRH 186
           EPSQ+LK A+V+LINYQDDAELATRA+PELTKLLNDED VVV KAA++V+QLSKKEASR 
Sbjct: 118 EPSQLLKSAIVHLINYQDDAELATRALPELTKLLNDEDPVVVTKAAMIVNQLSKKEASRR 177

Query: 187 AIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGS 246
           A+M SPQ+V+A+VRTMQNT+D++TARCT   LHNLSHHREGLLAIFKSGGIPALV+ML S
Sbjct: 178 ALMGSPQLVAAVVRTMQNTSDLDTARCTTSILHNLSHHREGLLAIFKSGGIPALVRMLSS 237

Query: 247 PVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAY 306
           PV+SVLFYAITTLHNLLL+QEGAKMAVRLA GLQKMV LLNK N KFLAITTDCLQ+LAY
Sbjct: 238 PVESVLFYAITTLHNLLLYQEGAKMAVRLADGLQKMVPLLNKNNPKFLAITTDCLQLLAY 297

Query: 307 GNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQAL 366
           GNQESKLIILA+GGPQALV IMR Y+YEKLLWTTSRVLKVLSVC SNKPAIVEAGGMQAL
Sbjct: 298 GNQESKLIILANGGPQALVQIMRNYSYEKLLWTTSRVLKVLSVCPSNKPAIVEAGGMQAL 357

Query: 367 GLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSN 426
           G HLT  S RLVQNCLWTLRNLSD ATKQEG+E +L  LV  L  DD+NV+TCA G LSN
Sbjct: 358 GKHLTSNSPRLVQNCLWTLRNLSDVATKQEGLESVLKILVNQLSVDDVNVLTCATGTLSN 417

Query: 427 LTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVR 486
           LTCNN KNK +V Q  G+EAL+  +LRAGD++DITEPA+CALRHLTSRH EAEMAQN+VR
Sbjct: 418 LTCNNSKNKTLVTQNSGVEALIHAILRAGDKDDITEPAVCALRHLTSRHPEAEMAQNSVR 477

Query: 487 LHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQD 546
           L+YG+P +VKLL+ P+ WPL+KAT+GLIRNLALCPANHAPL+E   IPRLVQLLV+AHQD
Sbjct: 478 LNYGIPAIVKLLNQPNQWPLVKATIGLIRNLALCPANHAPLQEAAVIPRLVQLLVKAHQD 537

Query: 547 TQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSP 606
            QR  +  GTQQ + +GVRMEEIVEGCTGALHILARD  NR+ I  LNTIPLFVQLLYS 
Sbjct: 538 AQRHVA-AGTQQPYTDGVRMEEIVEGCTGALHILARDPMNRMEIFRLNTIPLFVQLLYSS 596

Query: 607 IENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLFRMSEDK 666
           +ENIQRVAAGVLCELAQDKEAA+AI+AEGA+APL ELLHSRNEG ATYAAAVLFR+SEDK
Sbjct: 597 VENIQRVAAGVLCELAQDKEAADAIDAEGASAPLMELLHSRNEGTATYAAAVLFRISEDK 656

Query: 667 PQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEPLGYRQDDPSYRSFHSGGYGQ 726
             DY+KR+SVELT+SLF+ +P AW E A   + I    EP G    D +YR  +S     
Sbjct: 657 NPDYRKRVSVELTNSLFKHDPAAW-EAAQSMIPI---NEPYG-DDMDATYRPMYSSDVPL 711

Query: 727 DALGMDPMMEHEMGGHHPGADYPVDGLPD 755
           D L M   M+          DYP+D   D
Sbjct: 712 DPLEMHMDMD---------GDYPIDTYSD 731


>gi|31657114 armadillo repeat containing 4 [Homo sapiens]
          Length = 1044

 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 66/232 (28%), Positives = 104/232 (44%), Gaps = 14/232 (6%)

Query: 435 KMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVV 494
           ++ +  VGG+E L+  +       D  +  I +L+ L       ++ QN V L  GLP++
Sbjct: 487 QLAIRDVGGLEVLINLL-----ETDEVKCKIGSLKILKEISHNPQIRQNIVDLG-GLPIM 540

Query: 495 VKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRTSMG 554
           V +L  P H  L       I N+A        +R+ G I +LV LL  AH  T+      
Sbjct: 541 VNILDSP-HKSLKCLAAETIANVAKFKRARRVVRQHGGITKLVALLDCAHDSTK------ 593

Query: 555 GTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQRVA 614
              Q  +   R  E+      AL   ++   N+  IR    IPL  +LL +  EN+    
Sbjct: 594 -PAQSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPV 652

Query: 615 AGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLFRMSEDK 666
            G L E A ++    AI+AE     L + L+S NE +  + A  +++ +EDK
Sbjct: 653 VGTLQECASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDK 704



 Score = 70.9 bits (172), Expect = 4e-12
 Identities = 105/470 (22%), Positives = 198/470 (42%), Gaps = 51/470 (10%)

Query: 237 IPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAI 296
           I  LVK L     +    A+ ++ +  L QE  ++A+R  GGL+ ++ LL    VK    
Sbjct: 454 IQKLVKYLKGGNQTATVIALCSMRDFSLAQETCQLAIRDVGGLEVLINLLETDEVKCKIG 513

Query: 297 TTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPA 356
           +   L+ +++ N + +  I+  GG   +VNI+ +  ++ L    +  +  ++     +  
Sbjct: 514 SLKILKEISH-NPQIRQNIVDLGGLPIMVNILDS-PHKSLKCLAAETIANVAKFKRARRV 571

Query: 357 IVEAGGMQALG--LHLTDPSQRLVQNCLWTLRNL-------------SDAATKQEGME-- 399
           + + GG+  L   L     S +  Q+ L+  R++             S + T +E +   
Sbjct: 572 VRQHGGITKLVALLDCAHDSTKPAQSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKA 631

Query: 400 GLLGTLVQLLGSDDINVVTCAAGILSNLTC-NNYKNKMMVCQVGGIEALVRTVLRAGDRE 458
           G +  L +LL +   N++    G L       NY+  +   ++  IE LV+ +    + E
Sbjct: 632 GGIPLLARLLKTSHENMLIPVVGTLQECASEENYRAAIKAERI--IENLVKNL--NSENE 687

Query: 459 DITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLA 518
            + E    A+        E +  ++ VRLH GL  +  LL+   +   + A  G I   +
Sbjct: 688 QLQEHCAMAIYQCA----EDKETRDLVRLHGGLKPLASLLNNTDNKERLAAVTGAIWKCS 743

Query: 519 LCPANHAPLREQGAIPRLVQLLV---------------RAHQDTQRRT---SMGGTQQ-- 558
           +   N    RE  AI  LV LL                   Q+ + R      GG Q   
Sbjct: 744 ISKENVTKFREYKAIETLVGLLTDQPEEVLVNVVGALGECCQERENRVIVRKCGGIQPLV 803

Query: 559 QFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVL 618
             + G+  + ++   T A+   A +  + ++I  L+ + L   LL +P  +++  AA  L
Sbjct: 804 NLLVGIN-QALLVNVTKAVGACAVEPESMMIIDRLDGVRLLWSLLKNPHPDVKASAAWAL 862

Query: 619 CELAQD-KEAAEAIEA-EGATAPLTELLHSRNEGVATYAAAVLFRMSEDK 666
           C   ++ K+A E + +  G    +  LL S N+ V     A +  +++D+
Sbjct: 863 CPCIKNAKDAGEMVRSFVGGLELIVNLLKSDNKEVLASVCAAITNIAKDQ 912



 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 105/458 (22%), Positives = 193/458 (42%), Gaps = 45/458 (9%)

Query: 201  TMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLH 260
            ++    DVE ARC A  L + S       AI K+GGIP L ++L +  +++L   + TL 
Sbjct: 598  SLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQ 657

Query: 261  NLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQIL--AYGNQESKLIILAS 318
                 +E  + A++    ++ +V  LN  N +   +   C   +     ++E++ ++   
Sbjct: 658  E-CASEENYRAAIKAERIIENLVKNLNSENEQ---LQEHCAMAIYQCAEDKETRDLVRLH 713

Query: 319  GGPQALVNIM-RTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRL 377
            GG + L +++  T   E+L   T  + K  S+   N     E   ++ L   LTD  + +
Sbjct: 714  GGLKPLASLLNNTDNKERLAAVTGAIWK-CSISKENVTKFREYKAIETLVGLLTDQPEEV 772

Query: 378  VQNCLWTL------RNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNN 431
            + N +  L      R       K  G++ L+  LV +  +  +N VT A G  +      
Sbjct: 773  LVNVVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVN-VTKAVGACA----VE 827

Query: 432  YKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEA-EMAQNAVRLHYG 490
             ++ M++ ++ G+  L    L      D+   A  AL       ++A EM ++ V    G
Sbjct: 828  PESMMIIDRLDGVRLL--WSLLKNPHPDVKASAAWALCPCIKNAKDAGEMVRSFVG---G 882

Query: 491  LPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL------VRAH 544
            L ++V LL   +   ++ +    I N+A    N A + + G +P L +L       +R H
Sbjct: 883  LELIVNLLKSDNK-EVLASVCAAITNIAKDQENLAVITDHGVVPLLSKLANTNNNKLRHH 941

Query: 545  --QDTQRRTSMGGTQQQFVEGVRMEEIV-----------EGCTGALHILARDVHNRIVIR 591
              +   R    G  +  F E   +  +V                AL+ L+ D  N I + 
Sbjct: 942  LAEAISRCCMWGRNRVAFGEHKAVAPLVRYLKSNDTNVHRATAQALYQLSEDADNCITMH 1001

Query: 592  GLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAE 629
                + L + ++ SP +++Q  AAG +  + +   A E
Sbjct: 1002 ENGAVKLLLDMVGSPDQDLQEAAAGCISNIRRLALATE 1039


>gi|189409124 armadillo repeat containing 3 [Homo sapiens]
          Length = 872

 Score = 67.0 bits (162), Expect = 6e-11
 Identities = 88/445 (19%), Positives = 174/445 (39%), Gaps = 55/445 (12%)

Query: 152 AIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETA 211
           A+  LTKLL  ED++V  + A M+  +         ++R   ++++++  +    +V   
Sbjct: 68  AVEPLTKLLTHEDKIV-RRNATMIFGILASNNDVKKLLRELDVMNSVIAQLAPEEEVVIH 126

Query: 212 RCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKM 271
              +  L N+S      + IF+ GG+  L+++L SP   V   ++  ++NL+   +  + 
Sbjct: 127 EFASLCLANMSAEYTSKVQIFEHGGLEPLIRLLSSPDPDVKKNSMECIYNLVQDFQ-CRA 185

Query: 272 AVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTY 331
            ++    +  ++ LL         +    L ++A  ++ES+ ++  + G   L+ I+ T 
Sbjct: 186 KLQELNAIPPILDLLKSEYPVIQLLALKTLGVIA-NDKESRTMLRDNQGLDHLIKILETK 244

Query: 332 TYEKL--------------------LWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLT 371
               L                    +  T  + K+LS   ++    ++    +A+     
Sbjct: 245 ELNDLHIEALAVIANCLEDMDTMVQIQQTGGLKKLLSFAENSTIPDIQKNAAKAITKAAY 304

Query: 372 DPSQRL------VQNCLWTLRNLSDAATKQEGMEGL-----------------LGTLVQL 408
           DP  R       V+ CL  L    +  TK    + +                 +  L+QL
Sbjct: 305 DPENRKLFHEQEVEKCLVALLGSENDGTKIAASQAISAMCENSGSKDFFNNQGIPQLIQL 364

Query: 409 LGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICAL 468
           L SD+  V   AA  L+NLT  N  N     +  GI+ L+   L +  R+     A   L
Sbjct: 365 LKSDNEEVREAAALALANLTTCNPANANAAAEADGIDPLIN--LLSSKRDGAIANAATVL 422

Query: 469 RHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPAN-HAPL 527
            ++  +       QN   +H     ++  L   +   ++++   L      C       L
Sbjct: 423 TNMAMQEPLRLNIQNHDIMH----AIISPLRSAN--TVVQSKAALAVTATACDVEARTEL 476

Query: 528 REQGAIPRLVQLLVRAHQDTQRRTS 552
           R  G +  LV+LL   + + ++  S
Sbjct: 477 RNSGGLEPLVELLRSKNDEVRKHAS 501



 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 99/441 (22%), Positives = 168/441 (38%), Gaps = 53/441 (12%)

Query: 240 LVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTD 299
           +V ML SP + +L  A   ++   L  E  K  +   G ++ +  LL   +       T 
Sbjct: 30  VVLMLNSPEEEILAKACEAIYKFALKGEENKTTLLELGAVEPLTKLLTHEDKIVRRNATM 89

Query: 300 CLQILAYGNQESKLI--------ILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCS 351
              ILA  N   KL+        ++A   P+  V I             S  L  +S   
Sbjct: 90  IFGILASNNDVKKLLRELDVMNSVIAQLAPEEEVVIHE---------FASLCLANMSAEY 140

Query: 352 SNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGL--LGTLVQLL 409
           ++K  I E GG++ L   L+ P   + +N +  + NL      +  ++ L  +  ++ LL
Sbjct: 141 TSKVQIFEHGGLEPLIRLLSSPDPDVKKNSMECIYNLVQDFQCRAKLQELNAIPPILDLL 200

Query: 410 GSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALR 469
            S +  V+   A     +  N+ +++ M+    G++ L++ +L   +  D+   A+  + 
Sbjct: 201 KS-EYPVIQLLALKTLGVIANDKESRTMLRDNQGLDHLIK-ILETKELNDLHIEALAVIA 258

Query: 470 H-LTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLR 528
           + L       ++ Q       GL  ++      +   + K     I   A  P N     
Sbjct: 259 NCLEDMDTMVQIQQTG-----GLKKLLSFAENSTIPDIQKNAAKAITKAAYDPENRKLFH 313

Query: 529 EQGAIPRLVQLLVRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRI 588
           EQ     LV LL              G++    +    + I   C  +    ++D  N  
Sbjct: 314 EQEVEKCLVALL--------------GSENDGTKIAASQAISAMCENS---GSKDFFNN- 355

Query: 589 VIRGLNTIPLFVQLLYSPIENIQRVAAGVLCEL--AQDKEAAEAIEAEGATAPLTELLHS 646
                  IP  +QLL S  E ++  AA  L  L       A  A EA+G   PL  LL S
Sbjct: 356 -----QGIPQLIQLLKSDNEEVREAAALALANLTTCNPANANAAAEADGID-PLINLLSS 409

Query: 647 RNEGVATYAAAVLFRMSEDKP 667
           + +G    AA VL  M+  +P
Sbjct: 410 KRDGAIANAATVLTNMAMQEP 430



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 72/354 (20%), Positives = 142/354 (40%), Gaps = 40/354 (11%)

Query: 353 NKPAIVEAGGMQALGLHLTDPSQRLVQNCLWT---LRNLSDAATKQEGMEGLLGTLVQLL 409
           NK  ++E G ++ L   LT   + + +N       L + +D       ++ +   + QL 
Sbjct: 59  NKTTLLELGAVEPLTKLLTHEDKIVRRNATMIFGILASNNDVKKLLRELDVMNSVIAQLA 118

Query: 410 GSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALR 469
             +++ +   A+  L+N++   Y +K+ + + GG+E L+R  L +    D+ + ++  + 
Sbjct: 119 PEEEVVIHEFASLCLANMSAE-YTSKVQIFEHGGLEPLIR--LLSSPDPDVKKNSMECIY 175

Query: 470 HLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKA----TVGLIRNLALCPANHA 525
           +L    Q     Q        +P ++ LL   S +P+I+     T+G+I N      +  
Sbjct: 176 NLVQDFQCRAKLQEL----NAIPPILDLLK--SEYPVIQLLALKTLGVIAN---DKESRT 226

Query: 526 PLREQGAIPRLVQLLVRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVH 585
            LR+   +  L+++L     +     ++        +   M +I +  TG L  L     
Sbjct: 227 MLRDNQGLDHLIKILETKELNDLHIEALAVIANCLEDMDTMVQIQQ--TGGLKKLLSFAE 284

Query: 586 NRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLH 645
           N                  S I +IQ+ AA  + + A D E  +    +     L  LL 
Sbjct: 285 N------------------STIPDIQKNAAKAITKAAYDPENRKLFHEQEVEKCLVALLG 326

Query: 646 SRNEGVATYAAAVLFRMSEDK-PQDYKKRLSVELTSSLFRTEPMAWNETADLGL 698
           S N+G    A+  +  M E+   +D+     +     L +++     E A L L
Sbjct: 327 SENDGTKIAASQAISAMCENSGSKDFFNNQGIPQLIQLLKSDNEEVREAAALAL 380



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 91/471 (19%), Positives = 172/471 (36%), Gaps = 67/471 (14%)

Query: 226 EGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVAL 285
           E    + + G +  L K+L +  D ++    T +  +L      K  +R    +  ++A 
Sbjct: 58  ENKTTLLELGAVEPLTKLL-THEDKIVRRNATMIFGILASNNDVKKLLRELDVMNSVIAQ 116

Query: 286 LNKTN------------VKFLAITTDCLQILAYGNQESKLIILASGGP-------QALVN 326
           L                    A  T  +QI  +G  E  + +L+S  P       + + N
Sbjct: 117 LAPEEEVVIHEFASLCLANMSAEYTSKVQIFEHGGLEPLIRLLSSPDPDVKKNSMECIYN 176

Query: 327 IMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLR 386
           +++ +     L   + +  +L +  S  P +++   ++ LG+   D   R +      L 
Sbjct: 177 LVQDFQCRAKLQELNAIPPILDLLKSEYP-VIQLLALKTLGVIANDKESRTMLRDNQGLD 235

Query: 387 NLSDAATKQEGME---GLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGG 443
           +L      +E  +     L  +   L   D  V     G L  L      + +   Q   
Sbjct: 236 HLIKILETKELNDLHIEALAVIANCLEDMDTMVQIQQTGGLKKLLSFAENSTIPDIQKNA 295

Query: 444 IEALVRTVLRAGDREDITEPAI--CALRHLTSRHQEAEMAQNAVRL-------------H 488
            +A+ +      +R+   E  +  C +  L S +   ++A +                 +
Sbjct: 296 AKAITKAAYDPENRKLFHEQEVEKCLVALLGSENDGTKIAASQAISAMCENSGSKDFFNN 355

Query: 489 YGLPVVVKLLHPPSHWPLIKATVGLIRNLALC-PANHAPLREQGAIPRLVQLLVRAHQDT 547
            G+P +++LL   +   + +A    + NL  C PAN     E   I  L+ LL      +
Sbjct: 356 QGIPQLIQLLKSDNE-EVREAAALALANLTTCNPANANAAAEADGIDPLINLL------S 408

Query: 548 QRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIV--IRGLNTIPLFVQLLYS 605
            +R          +  + M+E +      L+I   D+ + I+  +R  NT+         
Sbjct: 409 SKRDGAIANAATVLTNMAMQEPLR-----LNIQNHDIMHAIISPLRSANTV--------- 454

Query: 606 PIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAA 656
               +Q  AA  +   A D EA   +   G   PL ELL S+N+ V  +A+
Sbjct: 455 ----VQSKAALAVTATACDVEARTELRNSGGLEPLVELLRSKNDEVRKHAS 501



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 52/263 (19%), Positives = 102/263 (38%), Gaps = 29/263 (11%)

Query: 404 TLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEP 463
           T+V +L S +  ++  A   +        +NK  + ++G +E L  T L   + + +   
Sbjct: 29  TVVLMLNSPEEEILAKACEAIYKFALKGEENKTTLLELGAVEPL--TKLLTHEDKIVRRN 86

Query: 464 AICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPAN 523
           A      L S +   ++ +    ++     V+  L P     + +     + N++    +
Sbjct: 87  ATMIFGILASNNDVKKLLRELDVMNS----VIAQLAPEEEVVIHEFASLCLANMSAEYTS 142

Query: 524 HAPLREQGAIPRLVQLLVRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARD 583
              + E G +  L++LL     D ++ +              ME         ++ L +D
Sbjct: 143 KVQIFEHGGLEPLIRLLSSPDPDVKKNS--------------ME--------CIYNLVQD 180

Query: 584 VHNRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTEL 643
              R  ++ LN IP  + LL S    IQ +A   L  +A DKE+   +        L ++
Sbjct: 181 FQCRAKLQELNAIPPILDLLKSEYPVIQLLALKTLGVIANDKESRTMLRDNQGLDHLIKI 240

Query: 644 LHSRN-EGVATYAAAVLFRMSED 665
           L ++    +   A AV+    ED
Sbjct: 241 LETKELNDLHIEALAVIANCLED 263


>gi|224589129 karyopherin 7 [Homo sapiens]
          Length = 516

 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 80/343 (23%), Positives = 142/343 (41%), Gaps = 44/343 (12%)

Query: 198 IVRTMQNTNDVETARCTAGTLHNLSHHREG-LLAIFKSGGIPALVKMLGSPVDSVL-FYA 255
           I++ + +++ V   + T      LS  +   L  + ++G IP +V+ L S +   L F A
Sbjct: 75  IIKGVNSSDPVLCFQATQTARKMLSQEKNPPLKLVIEAGLIPRMVEFLKSSLYPCLQFEA 134

Query: 256 ITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQ-ILAYGNQESKLI 314
              L N+         AV   G +Q ++ LL+ +NV        C Q + A GN      
Sbjct: 135 AWALTNIASGTSEQTRAVVEGGAIQPLIELLSSSNVAV------CEQAVWALGN------ 182

Query: 315 ILASGGPQALVNIMRTYTYEKLLWTTSRVLKVL----------SVCSSNKPAIVEAGGMQ 364
            +A  GP+   N++ +     LL   S  L +           ++C +  P   +    Q
Sbjct: 183 -IAGDGPEFRDNVITSNAIPHLLALISPTLPITFLRNITWTLSNLCRNKNPYPCDTAVKQ 241

Query: 365 ALG--LHLTD-PSQRLVQNCLWTLRNLSDAATKQEGM---EGLLGTLVQLLGSDDINVVT 418
            L   LHL       ++ +  W L  L+D + K+ G     G+L  LV L+ S ++NV+T
Sbjct: 242 ILPALLHLLQHQDSEVLSDACWALSYLTDGSNKRIGQVVNTGVLPRLVVLMTSSELNVLT 301

Query: 419 CAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTS---RH 475
            +   + N+     +   M    G +  L +  L   ++  I + A  AL ++ +    H
Sbjct: 302 PSLRTVGNIVTGTDEQTQMAIDAGMLNVLPQ--LLQHNKPSIQKEAAWALSNVAAGPCHH 359

Query: 476 QEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLA 518
            +  +A +       LP +V LL     + + K  V ++ N A
Sbjct: 360 IQQLLAYDV------LPPLVALL-KNGEFKVQKEAVWMVANFA 395



 Score = 31.6 bits (70), Expect = 3.0
 Identities = 26/75 (34%), Positives = 34/75 (45%), Gaps = 2/75 (2%)

Query: 596 IPLFVQLLYSPIEN-IQRVAAGVLCELAQD-KEAAEAIEAEGATAPLTELLHSRNEGVAT 653
           IP  V+ L S +   +Q  AA  L  +A    E   A+   GA  PL ELL S N  V  
Sbjct: 115 IPRMVEFLKSSLYPCLQFEAAWALTNIASGTSEQTRAVVEGGAIQPLIELLSSSNVAVCE 174

Query: 654 YAAAVLFRMSEDKPQ 668
            A   L  ++ D P+
Sbjct: 175 QAVWALGNIAGDGPE 189


>gi|4504897 karyopherin alpha 2 [Homo sapiens]
          Length = 529

 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 96/421 (22%), Positives = 170/421 (40%), Gaps = 60/421 (14%)

Query: 276 AGGLQKMVALLNKTNVKFLAITTD-CLQILAYGNQESKLIILASGGPQALVNIMRT---Y 331
           AG + K V+ L +T+   +   +   L  +A G  E    ++  G   A ++++ +   +
Sbjct: 118 AGLIPKFVSFLGRTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAH 177

Query: 332 TYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQR-----LVQNCLWTLR 386
             E+ +W    +    SV    +  +++ G +  L   L  P         ++N  WTL 
Sbjct: 178 ISEQAVWALGNIAGDGSVF---RDLVIKYGAVDPLLALLAVPDMSSLACGYLRNLTWTLS 234

Query: 387 NL---SDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGG 443
           NL    + A   + +E +L TLV+LL  DD  V+      +S LT    +   MV + G 
Sbjct: 235 NLCRNKNPAPPIDAVEQILPTLVRLLHHDDPEVLADTCWAISYLTDGPNERIGMVVKTGV 294

Query: 444 IEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYG-LPVVVKLLHPP- 501
           +  LV+  L       I  PA+ A+ ++ +   E    Q  V +  G L V   LL  P 
Sbjct: 295 VPQLVK--LLGASELPIVTPALRAIGNIVTGTDE----QTQVVIDAGALAVFPSLLTNPK 348

Query: 502 ------SHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRTSMGG 555
                 + W +   T G    +     NH      G +P LV +L +A   TQ+      
Sbjct: 349 TNIQKEATWTMSNITAGRQDQIQQV-VNH------GLVPFLVSVLSKADFKTQKEAVWAV 401

Query: 556 TQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPL----FVQLLYSPIENIQ 611
           T   +  G  +E+IV             VH  I+   +N +       + ++   I NI 
Sbjct: 402 T--NYTSGGTVEQIV-----------YLVHCGIIEPLMNLLTAKDTKIILVILDAISNIF 448

Query: 612 RVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVL---FRMSEDKPQ 668
           + A     +L + ++ +  IE  G    +  L +  NE V   + +++   F + E++ Q
Sbjct: 449 QAAE----KLGETEKLSIMIEECGGLDKIEALQNHENESVYKASLSLIEKYFSVEEEEDQ 504

Query: 669 D 669
           +
Sbjct: 505 N 505



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 89/401 (22%), Positives = 157/401 (39%), Gaps = 76/401 (18%)

Query: 122 VQRLAEPSQMLKHAVVNLINYQDDAELATR-----------AIPELTKLLND---EDQVV 167
           +++  +  QMLK    N+ ++ DDA    +           ++ ++ K +N    E+Q+ 
Sbjct: 38  LRKAKKDDQMLKRR--NVSSFPDDATSPLQENRNNQGTVNWSVDDIVKGINSSNVENQLQ 95

Query: 168 VNKAAVMVHQLSKKEASRHAIMRS--PQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHR 225
             +AA  +    K+    + I     P+ VS + RT  +    E+A          S   
Sbjct: 96  ATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRTDCSPIQFESAWALTNIASGTSEQT 155

Query: 226 EGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVAL 285
           +   A+   G IPA + +L SP                 H   ++ AV   G +    ++
Sbjct: 156 K---AVVDGGAIPAFISLLASP-----------------HAHISEQAVWALGNIAGDGSV 195

Query: 286 LNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLK 345
                +K+ A+    L +LA  +  S    LA G                L WT S    
Sbjct: 196 FRDLVIKYGAV-DPLLALLAVPDMSS----LACG------------YLRNLTWTLS---- 234

Query: 346 VLSVCSSNKPAIVEAGGMQALG-----LHLTDPSQRLVQNCLWTLRNLSDAATKQEGM-- 398
             ++C +  PA       Q L      LH  DP + L   C W +  L+D   ++ GM  
Sbjct: 235 --NLCRNKNPAPPIDAVEQILPTLVRLLHHDDP-EVLADTC-WAISYLTDGPNERIGMVV 290

Query: 399 -EGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDR 457
             G++  LV+LLG+ ++ +VT A   + N+     +   +V   G +   V   L    +
Sbjct: 291 KTGVVPQLVKLLGASELPIVTPALRAIGNIVTGTDEQTQVVIDAGAL--AVFPSLLTNPK 348

Query: 458 EDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLL 498
            +I + A   + ++T+  Q  +  Q  V  H  +P +V +L
Sbjct: 349 TNIQKEATWTMSNITAGRQ--DQIQQVVN-HGLVPFLVSVL 386



 Score = 37.4 bits (85), Expect = 0.054
 Identities = 60/279 (21%), Positives = 116/279 (41%), Gaps = 15/279 (5%)

Query: 145 DAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQN 204
           D  LA  A+P+++ L        +      +  L + +     I    Q++  +VR + +
Sbjct: 207 DPLLALLAVPDMSSLACG----YLRNLTWTLSNLCRNKNPAPPIDAVEQILPTLVRLLHH 262

Query: 205 TNDVETARCTAGTLHNLSHH-REGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLL 263
            +D E    T   +  L+    E +  + K+G +P LVK+LG+    ++  A+  + N++
Sbjct: 263 -DDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIV 321

Query: 264 LHQEGAKMAVRLAGGLQKMVALLN--KTNVKFLAITTDCLQILAYGNQESKLIILASGGP 321
              +     V  AG L    +LL   KTN++  A  T  +  +  G Q+    ++  G  
Sbjct: 322 TGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWT--MSNITAGRQDQIQQVVNHGLV 379

Query: 322 QALVNIMRT---YTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLV 378
             LV+++      T ++ +W  +      +V       +V  G ++ L   LT    +++
Sbjct: 380 PFLVSVLSKADFKTQKEAVWAVTNYTSGGTV--EQIVYLVHCGIIEPLMNLLTAKDTKII 437

Query: 379 QNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVV 417
              L  + N+  AA K    E L   + +  G D I  +
Sbjct: 438 LVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEAL 476


>gi|4502247 armadillo repeat protein [Homo sapiens]
          Length = 962

 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 94/404 (23%), Positives = 154/404 (38%), Gaps = 66/404 (16%)

Query: 237 IPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAI 296
           +P ++ ML  PVD V   A   L +L    EG K  VR   GL  +VALL+    +    
Sbjct: 360 LPEVLAMLRHPVDPVKANAAAYLQHLCFENEGVKRRVRQLRGLPLLVALLDHPRAEVRRR 419

Query: 297 TTDCLQILAYG-NQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKP 355
               L+ L+YG + ++K  I   GG  ALV ++R     ++    +  L  LS     K 
Sbjct: 420 ACGALRNLSYGRDTDNKAAIRDCGGVPALVRLLRAARDNEVRELVTGTLWNLSSYEPLKM 479

Query: 356 AIVEAGGMQALGLHLTDPSQ------------------RLVQNCLWTLRNLS----DAAT 393
            I++  G+Q L   +  P                     + +N    LRN+S    +A  
Sbjct: 480 VIID-HGLQTLTHEVIVPHSGWEREPNEDSKPRDAEWTTVFKNTSGCLRNVSSDGAEARR 538

Query: 394 KQEGMEGLLGTLVQLLGS-------DDINVVTCAAGILSNLTCNNYK-----NKMMVCQV 441
           +    EGL+  L+  L S       D+ +V  C   I+ NL+ + +K     ++    + 
Sbjct: 539 RLRECEGLVDALLHALQSAVGRKDTDNKSVENCVC-IMRNLSYHVHKEVPGADRYQEAEP 597

Query: 442 GGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQN--------------AVRL 487
           G + + V +  R  D                   ++ EM +N                 L
Sbjct: 598 GPLGSAVGSQRRRRDDASCFGGKKAKEEWFHQGKKDGEMDRNFDTLDLPKRTEAAKGFEL 657

Query: 488 HYGLPVV---VKLLHPPSHWPLIKATVGLIRNLAL-----CPANHAPLREQGAIPRLVQL 539
            Y   VV   + LL    ++  ++A  G ++NL+           A +R++  +P LV+L
Sbjct: 658 LYQPEVVRLYLSLLTESRNFNTLEAAAGALQNLSAGNWMWATYIRATVRKERGLPVLVEL 717

Query: 540 L-------VRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGA 576
           L       VRA     R  S+    +  +    M E+V     A
Sbjct: 718 LQSETDKVVRAVAIALRNLSLDRRNKDLIGSYAMAELVRNVRNA 761



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 51/195 (26%), Positives = 89/195 (45%), Gaps = 17/195 (8%)

Query: 99  FPETLDEGMQIPSTQFDAAHPTNVQRLAEPSQMLKHAVVNLINYQDDAELATRA------ 152
           + +T D+G ++   +   A P     LA+P +    ++  L+      + A +       
Sbjct: 301 YEDTADDGGELADER--PAFPMVTAPLAQPERGSMGSLDRLVRRSPSVDSARKEPRWRDP 358

Query: 153 -IPELTKLLNDE-DQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVET 210
            +PE+  +L    D V  N AA + H   + E  +  + R  + +  +V  + +    E 
Sbjct: 359 ELPEVLAMLRHPVDPVKANAAAYLQHLCFENEGVKRRV-RQLRGLPLLVALLDHPR-AEV 416

Query: 211 ARCTAGTLHNLSHHRE--GLLAIFKSGGIPALVKMLGSPVDSVLFYAIT-TLHNLLLHQE 267
            R   G L NLS+ R+     AI   GG+PALV++L +  D+ +   +T TL NL  + E
Sbjct: 417 RRRACGALRNLSYGRDTDNKAAIRDCGGVPALVRLLRAARDNEVRELVTGTLWNLSSY-E 475

Query: 268 GAKMAVRLAGGLQKM 282
             KM + +  GLQ +
Sbjct: 476 PLKMVI-IDHGLQTL 489



 Score = 31.2 bits (69), Expect = 3.9
 Identities = 54/209 (25%), Positives = 85/209 (40%), Gaps = 46/209 (22%)

Query: 402 LGTLVQLLGSDDINVVTCAAGILSNLTCN-NYKNKMMVCQVGGIEALVRTVLRAGDREDI 460
           L  LV LL      V   A G L NL+   +  NK  +   GG+ ALVR +LRA    ++
Sbjct: 402 LPLLVALLDHPRAEVRRRACGALRNLSYGRDTDNKAAIRDCGGVPALVR-LLRAARDNEV 460

Query: 461 TEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVV-KLLHPPSHW--------------- 504
            E     L +L+S ++  +M    V + +GL  +  +++ P S W               
Sbjct: 461 RELVTGTLWNLSS-YEPLKM----VIIDHGLQTLTHEVIVPHSGWEREPNEDSKPRDAEW 515

Query: 505 -PLIKATVGLIRNLALCPAN-HAPLRE-QGAIPRLVQLLVRA--HQDTQRRTSMGGTQQQ 559
             + K T G +RN++   A     LRE +G +  L+  L  A   +DT  ++        
Sbjct: 516 TTVFKNTSGCLRNVSSDGAEARRRLRECEGLVDALLHALQSAVGRKDTDNKS-------- 567

Query: 560 FVEGVRMEEIVEGCTGALHILARDVHNRI 588
                     VE C   +  L+  VH  +
Sbjct: 568 ----------VENCVCIMRNLSYHVHKEV 586


>gi|32526896 armadillo repeat containing 8 isoform 2 [Homo sapiens]
          Length = 659

 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 56/253 (22%), Positives = 110/253 (43%), Gaps = 9/253 (3%)

Query: 270 KMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMR 329
           K  +     + ++V  L++++VK       CL  L+   Q+ +         + L+ +++
Sbjct: 363 KKIIETENMMDRIVTGLSESSVKVRLAAVRCLHSLSRSVQQLRTSFQDHAVWKPLMKVLQ 422

Query: 330 TYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLS 389
               E L+  +S +  +L   S +K  I+E+G ++ L       +  L  N +W L N++
Sbjct: 423 NAPDEILVVASSMLCNLLLEFSPSKEPILESGAVELLCGLTQSENPALRVNGIWALMNMA 482

Query: 390 DAATKQEGMEGL--LGT--LVQLLGSDDINVVTCAAGILSN-LTCNNYKNKMMVCQVGGI 444
             A ++   + L  L T  L +LL   D+NV+    G+L N L+   + +K+M      I
Sbjct: 483 FQAEQKIKADILRSLSTEQLFRLLSDSDLNVLMKTLGLLRNLLSTRPHIDKIMSTHGKQI 542

Query: 445 EALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHW 504
              V  +L      ++ E  +C L ++     +   A++ +  +  +   +K     SH 
Sbjct: 543 MQAVTLILEGEHNIEVKEQTLCILANIA----DGTTAKDLIMTNDDILQKIKYYMGHSHV 598

Query: 505 PLIKATVGLIRNL 517
            L  A +  I NL
Sbjct: 599 KLQLAAMFCISNL 611


>gi|11034811 catenin (cadherin-associated protein), delta 2 (neural
           plakophilin-related arm-repeat protein) [Homo sapiens]
          Length = 1225

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 58/223 (26%), Positives = 96/223 (43%), Gaps = 33/223 (14%)

Query: 237 IPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAI 296
           +P +++ML     SV   A   L +L       K  +R  GG+Q +V LL+    +    
Sbjct: 552 LPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRRQGGIQLLVDLLDHRMTEVHRS 611

Query: 297 TTDCLQILAYG--NQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNK 354
               L+ L YG  N ++K+ +   GG  ALV ++R  T  ++    + VL  LS C + K
Sbjct: 612 ACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRKTTDLEIRELVTGVLWNLSSCDALK 671

Query: 355 PAIVEAGGMQALGLHLTDP------------------SQRLVQNCLWTLRNLSDAATKQ- 395
             I++   +  L   +  P                  S ++++N    LRN+S A  +  
Sbjct: 672 MPIIQ-DALAVLTNAVIIPHSGWENSPLQDDRKIQLHSSQVLRNATGCLRNVSSAGEEAR 730

Query: 396 ------EGM-EGLLGTLVQLLGSDDIN---VVTCAAGILSNLT 428
                 +G+ + LL  +   LGS +I+   V  C   IL NL+
Sbjct: 731 RRMRECDGLTDALLYVIQSALGSSEIDSKTVENCVC-ILRNLS 772



 Score = 39.7 bits (91), Expect = 0.011
 Identities = 89/406 (21%), Positives = 160/406 (39%), Gaps = 75/406 (18%)

Query: 153 IPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETAR 212
           +PE+ ++L  +   V + AA  +  L   +    A +R    +  +V  + +    E  R
Sbjct: 552 LPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRRQGGIQLLVDLLDHRM-TEVHR 610

Query: 213 CTAGTLHNLSHHR---EGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGA 269
              G L NL + +   +  +A+   GGIPALV++L    D  +   +T +   L   +  
Sbjct: 611 SACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRKTTDLEIRELVTGVLWNLSSCDAL 670

Query: 270 KMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMR 329
           KM +     +Q  +A+L                I+ +   E+         P      ++
Sbjct: 671 KMPI-----IQDALAVLTNA------------VIIPHSGWEN--------SPLQDDRKIQ 705

Query: 330 TYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHL-------TDPSQRLVQNCL 382
            ++ + L   T  +  V S     +  + E  G+    L++       ++   + V+NC+
Sbjct: 706 LHSSQVLRNATGCLRNVSSAGEEARRRMRECDGLTDALLYVIQSALGSSEIDSKTVENCV 765

Query: 383 WTLRNLSD--AATKQEGMEGLLGTLVQLLGSDDINVVTCAAG---ILSNLTCNNYKNKMM 437
             LRNLS   AA   +G         Q +G+D+++ + C         +  C   K K  
Sbjct: 766 CILRNLSYRLAAETSQG---------QHMGTDELDGLLCGEANGKDAESSGCWGKKKKKK 816

Query: 438 VCQ-----VG----------GIEAL--------VRTVLRAGDREDITEPAICALRHLTSR 474
             Q     VG          GI+ L          T+L      D  E A  AL++L + 
Sbjct: 817 KSQDQWDGVGPLPDCAEPPKGIQMLWHPSIVKPYLTLLSECSNPDTLEGAAGALQNLAAG 876

Query: 475 HQE-AEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLAL 519
             + +   + AVR   GLP++V+LL   +   ++ A    +RN+AL
Sbjct: 877 SWKWSVYIRAAVRKEKGLPILVELLRIDND-RVVCAVATALRNMAL 921



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 41/176 (23%), Positives = 77/176 (43%), Gaps = 8/176 (4%)

Query: 402 LGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDIT 461
           L  ++Q+L     +V + AA  L +L   + K K  + + GGI+ LV   L      ++ 
Sbjct: 552 LPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRRQGGIQLLVD--LLDHRMTEVH 609

Query: 462 EPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCP 521
             A  ALR+L       +  + A++   G+P +V+LL   +   + +   G++ NL+ C 
Sbjct: 610 RSACGALRNLVYGKANDDN-KIALKNCGGIPALVRLLRKTTDLEIRELVTGVLWNLSSCD 668

Query: 522 ANHAPLREQGAIPRLVQLLVRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGAL 577
           A   P+  Q A+  L   ++  H   +        + Q    +   +++   TG L
Sbjct: 669 ALKMPI-IQDALAVLTNAVIIPHSGWENSPLQDDRKIQ----LHSSQVLRNATGCL 719


>gi|189011568 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 64/263 (24%), Positives = 115/263 (43%), Gaps = 22/263 (8%)

Query: 424 LSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQN 483
           L+NLT  +  NK  +C + G    +   L++ + ED+ +     LR+L+ R      ++ 
Sbjct: 505 LTNLTFGDVANKATLCSMKGCMRALVAQLKS-ESEDLQQVIASVLRNLSWRADVN--SKK 561

Query: 484 AVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNL-ALCPANHAPL-REQGAIPRLVQLLV 541
            +R    +  +++          +K+ +  + NL A C  N A +    GA+  LV  L 
Sbjct: 562 TLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLT 621

Query: 542 -RAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFV 600
            R+  +T      GG   + V                 ++A +  +R ++R  N +   +
Sbjct: 622 YRSQTNTLAIIESGGGILRNVSS---------------LIATNEDHRQILRENNCLQTLL 666

Query: 601 QLLYSPIENIQRVAAGVLCEL-AQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVL 659
           Q L S    I   A G L  L A++ +  EA+   GA + L  L+HS+++ +A  +AA L
Sbjct: 667 QHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAMGSAAAL 726

Query: 660 FRMSEDKPQDYKKRLSVELTSSL 682
             +  ++P  YK    +   SSL
Sbjct: 727 RNLMANRPAKYKDANIMSPGSSL 749



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 74/306 (24%), Positives = 124/306 (40%), Gaps = 44/306 (14%)

Query: 133 KHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVM-VHQLSKKEASRHAIMRS 191
           +HA+  L   Q  AEL  +   E+  L ND   + + + A M +  L+  + +  A + S
Sbjct: 463 RHAMNELGGLQAIAELL-QVDCEMYGLTNDHYSITLRRYAGMALTNLTFGDVANKATLCS 521

Query: 192 PQ-MVSAIVRTMQNTNDVETARCTAGTLHNLSHHRE--GLLAIFKSGGIPALVKM-LGSP 247
            +  + A+V  +++ ++ +  +  A  L NLS   +      + + G + AL++  L   
Sbjct: 522 MKGCMRALVAQLKSESE-DLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVK 580

Query: 248 VDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYG 307
            +S L   ++ L NL  H    K  +    G            + FL  T      L Y 
Sbjct: 581 KESTLKSVLSALWNLSAHCTENKADICAVDGA-----------LAFLVGT------LTYR 623

Query: 308 NQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALG 367
           +Q + L I+ SGG      I+R             V  +++    ++  + E   +Q L 
Sbjct: 624 SQTNTLAIIESGG-----GILRN------------VSSLIATNEDHRQILRENNCLQTLL 666

Query: 368 LHLTDPSQRLVQNCLWTLRNLSDAATK-QEGM--EGLLGTLVQLLGSDDINVVTCAAGIL 424
            HL   S  +V N   TL NLS    K QE +   G +  L  L+ S    +   +A  L
Sbjct: 667 QHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAMGSAAAL 726

Query: 425 SNLTCN 430
            NL  N
Sbjct: 727 RNLMAN 732


>gi|189011566 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 64/263 (24%), Positives = 115/263 (43%), Gaps = 22/263 (8%)

Query: 424 LSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQN 483
           L+NLT  +  NK  +C + G    +   L++ + ED+ +     LR+L+ R      ++ 
Sbjct: 505 LTNLTFGDVANKATLCSMKGCMRALVAQLKS-ESEDLQQVIASVLRNLSWRADVN--SKK 561

Query: 484 AVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNL-ALCPANHAPL-REQGAIPRLVQLLV 541
            +R    +  +++          +K+ +  + NL A C  N A +    GA+  LV  L 
Sbjct: 562 TLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLT 621

Query: 542 -RAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFV 600
            R+  +T      GG   + V                 ++A +  +R ++R  N +   +
Sbjct: 622 YRSQTNTLAIIESGGGILRNVSS---------------LIATNEDHRQILRENNCLQTLL 666

Query: 601 QLLYSPIENIQRVAAGVLCEL-AQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVL 659
           Q L S    I   A G L  L A++ +  EA+   GA + L  L+HS+++ +A  +AA L
Sbjct: 667 QHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAMGSAAAL 726

Query: 660 FRMSEDKPQDYKKRLSVELTSSL 682
             +  ++P  YK    +   SSL
Sbjct: 727 RNLMANRPAKYKDANIMSPGSSL 749



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 74/306 (24%), Positives = 124/306 (40%), Gaps = 44/306 (14%)

Query: 133 KHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVM-VHQLSKKEASRHAIMRS 191
           +HA+  L   Q  AEL  +   E+  L ND   + + + A M +  L+  + +  A + S
Sbjct: 463 RHAMNELGGLQAIAELL-QVDCEMYGLTNDHYSITLRRYAGMALTNLTFGDVANKATLCS 521

Query: 192 PQ-MVSAIVRTMQNTNDVETARCTAGTLHNLSHHRE--GLLAIFKSGGIPALVKM-LGSP 247
            +  + A+V  +++ ++ +  +  A  L NLS   +      + + G + AL++  L   
Sbjct: 522 MKGCMRALVAQLKSESE-DLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVK 580

Query: 248 VDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYG 307
            +S L   ++ L NL  H    K  +    G            + FL  T      L Y 
Sbjct: 581 KESTLKSVLSALWNLSAHCTENKADICAVDGA-----------LAFLVGT------LTYR 623

Query: 308 NQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALG 367
           +Q + L I+ SGG      I+R             V  +++    ++  + E   +Q L 
Sbjct: 624 SQTNTLAIIESGG-----GILRN------------VSSLIATNEDHRQILRENNCLQTLL 666

Query: 368 LHLTDPSQRLVQNCLWTLRNLSDAATK-QEGM--EGLLGTLVQLLGSDDINVVTCAAGIL 424
            HL   S  +V N   TL NLS    K QE +   G +  L  L+ S    +   +A  L
Sbjct: 667 QHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAMGSAAAL 726

Query: 425 SNLTCN 430
            NL  N
Sbjct: 727 RNLMAN 732


>gi|53759122 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 64/263 (24%), Positives = 115/263 (43%), Gaps = 22/263 (8%)

Query: 424 LSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQN 483
           L+NLT  +  NK  +C + G    +   L++ + ED+ +     LR+L+ R      ++ 
Sbjct: 505 LTNLTFGDVANKATLCSMKGCMRALVAQLKS-ESEDLQQVIASVLRNLSWRADVN--SKK 561

Query: 484 AVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNL-ALCPANHAPL-REQGAIPRLVQLLV 541
            +R    +  +++          +K+ +  + NL A C  N A +    GA+  LV  L 
Sbjct: 562 TLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLT 621

Query: 542 -RAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFV 600
            R+  +T      GG   + V                 ++A +  +R ++R  N +   +
Sbjct: 622 YRSQTNTLAIIESGGGILRNVSS---------------LIATNEDHRQILRENNCLQTLL 666

Query: 601 QLLYSPIENIQRVAAGVLCEL-AQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVL 659
           Q L S    I   A G L  L A++ +  EA+   GA + L  L+HS+++ +A  +AA L
Sbjct: 667 QHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAMGSAAAL 726

Query: 660 FRMSEDKPQDYKKRLSVELTSSL 682
             +  ++P  YK    +   SSL
Sbjct: 727 RNLMANRPAKYKDANIMSPGSSL 749



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 74/306 (24%), Positives = 124/306 (40%), Gaps = 44/306 (14%)

Query: 133 KHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVM-VHQLSKKEASRHAIMRS 191
           +HA+  L   Q  AEL  +   E+  L ND   + + + A M +  L+  + +  A + S
Sbjct: 463 RHAMNELGGLQAIAELL-QVDCEMYGLTNDHYSITLRRYAGMALTNLTFGDVANKATLCS 521

Query: 192 PQ-MVSAIVRTMQNTNDVETARCTAGTLHNLSHHRE--GLLAIFKSGGIPALVKM-LGSP 247
            +  + A+V  +++ ++ +  +  A  L NLS   +      + + G + AL++  L   
Sbjct: 522 MKGCMRALVAQLKSESE-DLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVK 580

Query: 248 VDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYG 307
            +S L   ++ L NL  H    K  +    G            + FL  T      L Y 
Sbjct: 581 KESTLKSVLSALWNLSAHCTENKADICAVDGA-----------LAFLVGT------LTYR 623

Query: 308 NQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALG 367
           +Q + L I+ SGG      I+R             V  +++    ++  + E   +Q L 
Sbjct: 624 SQTNTLAIIESGG-----GILRN------------VSSLIATNEDHRQILRENNCLQTLL 666

Query: 368 LHLTDPSQRLVQNCLWTLRNLSDAATK-QEGM--EGLLGTLVQLLGSDDINVVTCAAGIL 424
            HL   S  +V N   TL NLS    K QE +   G +  L  L+ S    +   +A  L
Sbjct: 667 QHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAMGSAAAL 726

Query: 425 SNLTCN 430
            NL  N
Sbjct: 727 RNLMAN 732


>gi|146231975 catenin, delta 1 isoform 3A [Homo sapiens]
          Length = 832

 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 71/284 (25%), Positives = 119/284 (41%), Gaps = 46/284 (16%)

Query: 221 LSHHREGLLAIFKS---GG----------IPALVKMLGSPVDSVLFYAITTLHNLLLHQE 267
           L+ H  G LA   S   GG          +P ++ MLG  +D+V   A   L +L    +
Sbjct: 238 LAQHERGSLASLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRND 297

Query: 268 GAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYG-NQESKLIILASGGPQALVN 326
             K  VR   G+  +V LL+    +        L+ +++G +Q++K+ I    G  ALV 
Sbjct: 298 KVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVR 357

Query: 327 IMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLH-LTDPSQRLVQNCLWTL 385
           ++R      L    +  L  LS   S K  IV+        LH LTD  + ++ +  W  
Sbjct: 358 LLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDH------ALHALTD--EVIIPHSGWER 409

Query: 386 RNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTC--NNYKNKMMVCQVGG 443
               D   +    E               +V+T  AG L N++   +  + K+  C  G 
Sbjct: 410 EPNEDCKPRHIEWE---------------SVLTNTAGCLRNVSSERSEARRKLRECD-GL 453

Query: 444 IEALVRTVLRAGDRED----ITEPAICALRHLTSR-HQEAEMAQ 482
           ++AL+  V     ++D    + E  +C LR+L+ + H+E   A+
Sbjct: 454 VDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAE 497



 Score = 37.4 bits (85), Expect = 0.054
 Identities = 94/427 (22%), Positives = 162/427 (37%), Gaps = 66/427 (15%)

Query: 153 IPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTN-DVETA 211
           +PE+  +L      V + AA  +  L  +       +R  + +  +V  + +   +V   
Sbjct: 267 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 326

Query: 212 RCTAGTLHNLSHHRE--GLLAIFKSGGIPALVKMLGSPVDSVLFYAIT-TLHNLLLHQEG 268
            C  G L N+S  R+    +AI    G+PALV++L    D  L   IT TL NL  H + 
Sbjct: 327 AC--GALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSH-DS 383

Query: 269 AKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVN-- 326
            KM +                +    A+T +              +I+   G +   N  
Sbjct: 384 IKMEI---------------VDHALHALTDE--------------VIIPHSGWEREPNED 414

Query: 327 -IMRTYTYEKLLWTTSRVLK-VLSVCSSNKPAIVEAGGMQALGLHLT-------DPSQRL 377
              R   +E +L  T+  L+ V S  S  +  + E  G+    + +        D   +L
Sbjct: 415 CKPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKL 474

Query: 378 VQNCLWTLRNLSDAATKQ----EGMEGLLGTLVQLLGSDDINVVTCAAG----ILSNLTC 429
           V+NC+  LRNLS    ++    E  +     +    G    +      G     + +   
Sbjct: 475 VENCVCLLRNLSYQVHREIPQAERYQEAAPNVANNTGPHAASCFGAKKGKGKKPIEDPAN 534

Query: 430 NNYKNKMMVCQVGGIEALVR--------TVLRAGDREDITEPAICALRHL-TSRHQEAEM 480
           +            G E L +        ++L+      I E +  A+++L   R      
Sbjct: 535 DTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRY 594

Query: 481 AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL 540
            ++A+R    L  +  LL    H  ++KA  G +RNLA+  A +  L  + AIP LV+ L
Sbjct: 595 IRSALRQEKALSAIADLL-TNEHERVVKAASGALRNLAV-DARNKELIGKHAIPNLVKNL 652

Query: 541 VRAHQDT 547
               Q++
Sbjct: 653 PGGQQNS 659


>gi|146231948 catenin, delta 1 isoform 3A [Homo sapiens]
          Length = 832

 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 71/284 (25%), Positives = 119/284 (41%), Gaps = 46/284 (16%)

Query: 221 LSHHREGLLAIFKS---GG----------IPALVKMLGSPVDSVLFYAITTLHNLLLHQE 267
           L+ H  G LA   S   GG          +P ++ MLG  +D+V   A   L +L    +
Sbjct: 238 LAQHERGSLASLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRND 297

Query: 268 GAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYG-NQESKLIILASGGPQALVN 326
             K  VR   G+  +V LL+    +        L+ +++G +Q++K+ I    G  ALV 
Sbjct: 298 KVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVR 357

Query: 327 IMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLH-LTDPSQRLVQNCLWTL 385
           ++R      L    +  L  LS   S K  IV+        LH LTD  + ++ +  W  
Sbjct: 358 LLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDH------ALHALTD--EVIIPHSGWER 409

Query: 386 RNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTC--NNYKNKMMVCQVGG 443
               D   +    E               +V+T  AG L N++   +  + K+  C  G 
Sbjct: 410 EPNEDCKPRHIEWE---------------SVLTNTAGCLRNVSSERSEARRKLRECD-GL 453

Query: 444 IEALVRTVLRAGDRED----ITEPAICALRHLTSR-HQEAEMAQ 482
           ++AL+  V     ++D    + E  +C LR+L+ + H+E   A+
Sbjct: 454 VDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAE 497



 Score = 37.4 bits (85), Expect = 0.054
 Identities = 94/427 (22%), Positives = 162/427 (37%), Gaps = 66/427 (15%)

Query: 153 IPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTN-DVETA 211
           +PE+  +L      V + AA  +  L  +       +R  + +  +V  + +   +V   
Sbjct: 267 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 326

Query: 212 RCTAGTLHNLSHHRE--GLLAIFKSGGIPALVKMLGSPVDSVLFYAIT-TLHNLLLHQEG 268
            C  G L N+S  R+    +AI    G+PALV++L    D  L   IT TL NL  H + 
Sbjct: 327 AC--GALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSH-DS 383

Query: 269 AKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVN-- 326
            KM +                +    A+T +              +I+   G +   N  
Sbjct: 384 IKMEI---------------VDHALHALTDE--------------VIIPHSGWEREPNED 414

Query: 327 -IMRTYTYEKLLWTTSRVLK-VLSVCSSNKPAIVEAGGMQALGLHLT-------DPSQRL 377
              R   +E +L  T+  L+ V S  S  +  + E  G+    + +        D   +L
Sbjct: 415 CKPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKL 474

Query: 378 VQNCLWTLRNLSDAATKQ----EGMEGLLGTLVQLLGSDDINVVTCAAG----ILSNLTC 429
           V+NC+  LRNLS    ++    E  +     +    G    +      G     + +   
Sbjct: 475 VENCVCLLRNLSYQVHREIPQAERYQEAAPNVANNTGPHAASCFGAKKGKGKKPIEDPAN 534

Query: 430 NNYKNKMMVCQVGGIEALVR--------TVLRAGDREDITEPAICALRHL-TSRHQEAEM 480
           +            G E L +        ++L+      I E +  A+++L   R      
Sbjct: 535 DTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRY 594

Query: 481 AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL 540
            ++A+R    L  +  LL    H  ++KA  G +RNLA+  A +  L  + AIP LV+ L
Sbjct: 595 IRSALRQEKALSAIADLL-TNEHERVVKAASGALRNLAV-DARNKELIGKHAIPNLVKNL 652

Query: 541 VRAHQDT 547
               Q++
Sbjct: 653 PGGQQNS 659


>gi|146231994 catenin, delta 1 isoform 3A [Homo sapiens]
          Length = 832

 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 71/284 (25%), Positives = 119/284 (41%), Gaps = 46/284 (16%)

Query: 221 LSHHREGLLAIFKS---GG----------IPALVKMLGSPVDSVLFYAITTLHNLLLHQE 267
           L+ H  G LA   S   GG          +P ++ MLG  +D+V   A   L +L    +
Sbjct: 238 LAQHERGSLASLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRND 297

Query: 268 GAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYG-NQESKLIILASGGPQALVN 326
             K  VR   G+  +V LL+    +        L+ +++G +Q++K+ I    G  ALV 
Sbjct: 298 KVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVR 357

Query: 327 IMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLH-LTDPSQRLVQNCLWTL 385
           ++R      L    +  L  LS   S K  IV+        LH LTD  + ++ +  W  
Sbjct: 358 LLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDH------ALHALTD--EVIIPHSGWER 409

Query: 386 RNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTC--NNYKNKMMVCQVGG 443
               D   +    E               +V+T  AG L N++   +  + K+  C  G 
Sbjct: 410 EPNEDCKPRHIEWE---------------SVLTNTAGCLRNVSSERSEARRKLRECD-GL 453

Query: 444 IEALVRTVLRAGDRED----ITEPAICALRHLTSR-HQEAEMAQ 482
           ++AL+  V     ++D    + E  +C LR+L+ + H+E   A+
Sbjct: 454 VDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAE 497



 Score = 37.4 bits (85), Expect = 0.054
 Identities = 94/427 (22%), Positives = 162/427 (37%), Gaps = 66/427 (15%)

Query: 153 IPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTN-DVETA 211
           +PE+  +L      V + AA  +  L  +       +R  + +  +V  + +   +V   
Sbjct: 267 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 326

Query: 212 RCTAGTLHNLSHHRE--GLLAIFKSGGIPALVKMLGSPVDSVLFYAIT-TLHNLLLHQEG 268
            C  G L N+S  R+    +AI    G+PALV++L    D  L   IT TL NL  H + 
Sbjct: 327 AC--GALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSH-DS 383

Query: 269 AKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVN-- 326
            KM +                +    A+T +              +I+   G +   N  
Sbjct: 384 IKMEI---------------VDHALHALTDE--------------VIIPHSGWEREPNED 414

Query: 327 -IMRTYTYEKLLWTTSRVLK-VLSVCSSNKPAIVEAGGMQALGLHLT-------DPSQRL 377
              R   +E +L  T+  L+ V S  S  +  + E  G+    + +        D   +L
Sbjct: 415 CKPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKL 474

Query: 378 VQNCLWTLRNLSDAATKQ----EGMEGLLGTLVQLLGSDDINVVTCAAG----ILSNLTC 429
           V+NC+  LRNLS    ++    E  +     +    G    +      G     + +   
Sbjct: 475 VENCVCLLRNLSYQVHREIPQAERYQEAAPNVANNTGPHAASCFGAKKGKGKKPIEDPAN 534

Query: 430 NNYKNKMMVCQVGGIEALVR--------TVLRAGDREDITEPAICALRHL-TSRHQEAEM 480
           +            G E L +        ++L+      I E +  A+++L   R      
Sbjct: 535 DTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRY 594

Query: 481 AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL 540
            ++A+R    L  +  LL    H  ++KA  G +RNLA+  A +  L  + AIP LV+ L
Sbjct: 595 IRSALRQEKALSAIADLL-TNEHERVVKAASGALRNLAV-DARNKELIGKHAIPNLVKNL 652

Query: 541 VRAHQDT 547
               Q++
Sbjct: 653 PGGQQNS 659


>gi|146231977 catenin, delta 1 isoform 3AC [Homo sapiens]
          Length = 838

 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 71/284 (25%), Positives = 119/284 (41%), Gaps = 46/284 (16%)

Query: 221 LSHHREGLLAIFKS---GG----------IPALVKMLGSPVDSVLFYAITTLHNLLLHQE 267
           L+ H  G LA   S   GG          +P ++ MLG  +D+V   A   L +L    +
Sbjct: 238 LAQHERGSLASLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRND 297

Query: 268 GAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYG-NQESKLIILASGGPQALVN 326
             K  VR   G+  +V LL+    +        L+ +++G +Q++K+ I    G  ALV 
Sbjct: 298 KVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVR 357

Query: 327 IMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLH-LTDPSQRLVQNCLWTL 385
           ++R      L    +  L  LS   S K  IV+        LH LTD  + ++ +  W  
Sbjct: 358 LLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDH------ALHALTD--EVIIPHSGWER 409

Query: 386 RNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTC--NNYKNKMMVCQVGG 443
               D   +    E               +V+T  AG L N++   +  + K+  C  G 
Sbjct: 410 EPNEDCKPRHIEWE---------------SVLTNTAGCLRNVSSERSEARRKLRECD-GL 453

Query: 444 IEALVRTVLRAGDRED----ITEPAICALRHLTSR-HQEAEMAQ 482
           ++AL+  V     ++D    + E  +C LR+L+ + H+E   A+
Sbjct: 454 VDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAE 497



 Score = 35.0 bits (79), Expect = 0.27
 Identities = 35/125 (28%), Positives = 56/125 (44%), Gaps = 7/125 (5%)

Query: 153 IPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTN-DVETA 211
           +PE+  +L      V + AA  +  L  +       +R  + +  +V  + +   +V   
Sbjct: 267 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 326

Query: 212 RCTAGTLHNLSHHRE--GLLAIFKSGGIPALVKMLGSPVDSVLFYAIT-TLHNLLLHQEG 268
            C  G L N+S  R+    +AI    G+PALV++L    D  L   IT TL NL  H + 
Sbjct: 327 AC--GALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSH-DS 383

Query: 269 AKMAV 273
            KM +
Sbjct: 384 IKMEI 388



 Score = 33.1 bits (74), Expect = 1.0
 Identities = 79/363 (21%), Positives = 139/363 (38%), Gaps = 50/363 (13%)

Query: 233 KSGGIPALVKMLGSPVDSVLFYAITTLHNLLL-HQEGAKMAVRLAGGLQKMVALLNKTNV 291
           K  GIP LV +L  P   V   A   L N+     +  K+A++   G+  +V LL K   
Sbjct: 305 KLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARD 364

Query: 292 KFLA--ITTDCLQILAYGNQESKLI-----------ILASGGPQALVNI---MRTYTYEK 335
             L   IT     + ++ + + +++           I+   G +   N     R   +E 
Sbjct: 365 MDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWES 424

Query: 336 LLWTTSRVLK-VLSVCSSNKPAIVEAGGMQALGLHLT-------DPSQRLVQNCLWTLRN 387
           +L  T+  L+ V S  S  +  + E  G+    + +        D   +LV+NC+  LRN
Sbjct: 425 VLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRN 484

Query: 388 LSDAATKQ----EGMEGLLGTLVQLLGSDDINVVTCAAGI----------LSNLTCNNYK 433
           LS    ++    E  +     +    G    +      G           + +   +   
Sbjct: 485 LSYQVHREIPQAERYQEAAPNVANNTGPHAASCFGAKKGKDEWFSRGKKPIEDPANDTVD 544

Query: 434 NKMMVCQVGGIEALVR--------TVLRAGDREDITEPAICALRHLTS-RHQEAEMAQNA 484
                    G E L +        ++L+      I E +  A+++L + R       ++A
Sbjct: 545 FPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSA 604

Query: 485 VRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAH 544
           +R    L  +  LL    H  ++KA  G +RNLA+  A +  L  + AIP LV+ L    
Sbjct: 605 LRQEKALSAIADLL-TNEHERVVKAASGALRNLAV-DARNKELIGKHAIPNLVKNLPGGQ 662

Query: 545 QDT 547
           Q++
Sbjct: 663 QNS 665


>gi|146231946 catenin, delta 1 isoform 3B [Homo sapiens]
          Length = 840

 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 71/284 (25%), Positives = 119/284 (41%), Gaps = 46/284 (16%)

Query: 221 LSHHREGLLAIFKS---GG----------IPALVKMLGSPVDSVLFYAITTLHNLLLHQE 267
           L+ H  G LA   S   GG          +P ++ MLG  +D+V   A   L +L    +
Sbjct: 238 LAQHERGSLASLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRND 297

Query: 268 GAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYG-NQESKLIILASGGPQALVN 326
             K  VR   G+  +V LL+    +        L+ +++G +Q++K+ I    G  ALV 
Sbjct: 298 KVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVR 357

Query: 327 IMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLH-LTDPSQRLVQNCLWTL 385
           ++R      L    +  L  LS   S K  IV+        LH LTD  + ++ +  W  
Sbjct: 358 LLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDH------ALHALTD--EVIIPHSGWER 409

Query: 386 RNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTC--NNYKNKMMVCQVGG 443
               D   +    E               +V+T  AG L N++   +  + K+  C  G 
Sbjct: 410 EPNEDCKPRHIEWE---------------SVLTNTAGCLRNVSSERSEARRKLRECD-GL 453

Query: 444 IEALVRTVLRAGDRED----ITEPAICALRHLTSR-HQEAEMAQ 482
           ++AL+  V     ++D    + E  +C LR+L+ + H+E   A+
Sbjct: 454 VDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAE 497



 Score = 37.4 bits (85), Expect = 0.054
 Identities = 94/427 (22%), Positives = 162/427 (37%), Gaps = 66/427 (15%)

Query: 153 IPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTN-DVETA 211
           +PE+  +L      V + AA  +  L  +       +R  + +  +V  + +   +V   
Sbjct: 267 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 326

Query: 212 RCTAGTLHNLSHHRE--GLLAIFKSGGIPALVKMLGSPVDSVLFYAIT-TLHNLLLHQEG 268
            C  G L N+S  R+    +AI    G+PALV++L    D  L   IT TL NL  H + 
Sbjct: 327 AC--GALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSH-DS 383

Query: 269 AKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVN-- 326
            KM +                +    A+T +              +I+   G +   N  
Sbjct: 384 IKMEI---------------VDHALHALTDE--------------VIIPHSGWEREPNED 414

Query: 327 -IMRTYTYEKLLWTTSRVLK-VLSVCSSNKPAIVEAGGMQALGLHLT-------DPSQRL 377
              R   +E +L  T+  L+ V S  S  +  + E  G+    + +        D   +L
Sbjct: 415 CKPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKL 474

Query: 378 VQNCLWTLRNLSDAATKQ----EGMEGLLGTLVQLLGSDDINVVTCAAG----ILSNLTC 429
           V+NC+  LRNLS    ++    E  +     +    G    +      G     + +   
Sbjct: 475 VENCVCLLRNLSYQVHREIPQAERYQEAAPNVANNTGPHAASCFGAKKGKGKKPIEDPAN 534

Query: 430 NNYKNKMMVCQVGGIEALVR--------TVLRAGDREDITEPAICALRHL-TSRHQEAEM 480
           +            G E L +        ++L+      I E +  A+++L   R      
Sbjct: 535 DTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRY 594

Query: 481 AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL 540
            ++A+R    L  +  LL    H  ++KA  G +RNLA+  A +  L  + AIP LV+ L
Sbjct: 595 IRSALRQEKALSAIADLL-TNEHERVVKAASGALRNLAV-DARNKELIGKHAIPNLVKNL 652

Query: 541 VRAHQDT 547
               Q++
Sbjct: 653 PGGQQNS 659


>gi|146231991 catenin, delta 1 isoform 3AB [Homo sapiens]
          Length = 861

 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 71/284 (25%), Positives = 119/284 (41%), Gaps = 46/284 (16%)

Query: 221 LSHHREGLLAIFKS---GG----------IPALVKMLGSPVDSVLFYAITTLHNLLLHQE 267
           L+ H  G LA   S   GG          +P ++ MLG  +D+V   A   L +L    +
Sbjct: 238 LAQHERGSLASLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRND 297

Query: 268 GAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYG-NQESKLIILASGGPQALVN 326
             K  VR   G+  +V LL+    +        L+ +++G +Q++K+ I    G  ALV 
Sbjct: 298 KVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVR 357

Query: 327 IMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLH-LTDPSQRLVQNCLWTL 385
           ++R      L    +  L  LS   S K  IV+        LH LTD  + ++ +  W  
Sbjct: 358 LLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDH------ALHALTD--EVIIPHSGWER 409

Query: 386 RNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTC--NNYKNKMMVCQVGG 443
               D   +    E               +V+T  AG L N++   +  + K+  C  G 
Sbjct: 410 EPNEDCKPRHIEWE---------------SVLTNTAGCLRNVSSERSEARRKLRECD-GL 453

Query: 444 IEALVRTVLRAGDRED----ITEPAICALRHLTSR-HQEAEMAQ 482
           ++AL+  V     ++D    + E  +C LR+L+ + H+E   A+
Sbjct: 454 VDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAE 497



 Score = 37.4 bits (85), Expect = 0.054
 Identities = 94/427 (22%), Positives = 162/427 (37%), Gaps = 66/427 (15%)

Query: 153 IPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTN-DVETA 211
           +PE+  +L      V + AA  +  L  +       +R  + +  +V  + +   +V   
Sbjct: 267 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 326

Query: 212 RCTAGTLHNLSHHRE--GLLAIFKSGGIPALVKMLGSPVDSVLFYAIT-TLHNLLLHQEG 268
            C  G L N+S  R+    +AI    G+PALV++L    D  L   IT TL NL  H + 
Sbjct: 327 AC--GALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSH-DS 383

Query: 269 AKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVN-- 326
            KM +                +    A+T +              +I+   G +   N  
Sbjct: 384 IKMEI---------------VDHALHALTDE--------------VIIPHSGWEREPNED 414

Query: 327 -IMRTYTYEKLLWTTSRVLK-VLSVCSSNKPAIVEAGGMQALGLHLT-------DPSQRL 377
              R   +E +L  T+  L+ V S  S  +  + E  G+    + +        D   +L
Sbjct: 415 CKPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKL 474

Query: 378 VQNCLWTLRNLSDAATKQ----EGMEGLLGTLVQLLGSDDINVVTCAAG----ILSNLTC 429
           V+NC+  LRNLS    ++    E  +     +    G    +      G     + +   
Sbjct: 475 VENCVCLLRNLSYQVHREIPQAERYQEAAPNVANNTGPHAASCFGAKKGKGKKPIEDPAN 534

Query: 430 NNYKNKMMVCQVGGIEALVR--------TVLRAGDREDITEPAICALRHL-TSRHQEAEM 480
           +            G E L +        ++L+      I E +  A+++L   R      
Sbjct: 535 DTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRY 594

Query: 481 AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL 540
            ++A+R    L  +  LL    H  ++KA  G +RNLA+  A +  L  + AIP LV+ L
Sbjct: 595 IRSALRQEKALSAIADLL-TNEHERVVKAASGALRNLAV-DARNKELIGKHAIPNLVKNL 652

Query: 541 VRAHQDT 547
               Q++
Sbjct: 653 PGGQQNS 659


>gi|146231970 catenin, delta 1 isoform 3ABC [Homo sapiens]
          Length = 867

 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 71/284 (25%), Positives = 119/284 (41%), Gaps = 46/284 (16%)

Query: 221 LSHHREGLLAIFKS---GG----------IPALVKMLGSPVDSVLFYAITTLHNLLLHQE 267
           L+ H  G LA   S   GG          +P ++ MLG  +D+V   A   L +L    +
Sbjct: 238 LAQHERGSLASLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRND 297

Query: 268 GAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYG-NQESKLIILASGGPQALVN 326
             K  VR   G+  +V LL+    +        L+ +++G +Q++K+ I    G  ALV 
Sbjct: 298 KVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVR 357

Query: 327 IMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLH-LTDPSQRLVQNCLWTL 385
           ++R      L    +  L  LS   S K  IV+        LH LTD  + ++ +  W  
Sbjct: 358 LLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDH------ALHALTD--EVIIPHSGWER 409

Query: 386 RNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTC--NNYKNKMMVCQVGG 443
               D   +    E               +V+T  AG L N++   +  + K+  C  G 
Sbjct: 410 EPNEDCKPRHIEWE---------------SVLTNTAGCLRNVSSERSEARRKLRECD-GL 453

Query: 444 IEALVRTVLRAGDRED----ITEPAICALRHLTSR-HQEAEMAQ 482
           ++AL+  V     ++D    + E  +C LR+L+ + H+E   A+
Sbjct: 454 VDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAE 497



 Score = 35.0 bits (79), Expect = 0.27
 Identities = 35/125 (28%), Positives = 56/125 (44%), Gaps = 7/125 (5%)

Query: 153 IPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTN-DVETA 211
           +PE+  +L      V + AA  +  L  +       +R  + +  +V  + +   +V   
Sbjct: 267 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 326

Query: 212 RCTAGTLHNLSHHRE--GLLAIFKSGGIPALVKMLGSPVDSVLFYAIT-TLHNLLLHQEG 268
            C  G L N+S  R+    +AI    G+PALV++L    D  L   IT TL NL  H + 
Sbjct: 327 AC--GALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSH-DS 383

Query: 269 AKMAV 273
            KM +
Sbjct: 384 IKMEI 388



 Score = 33.1 bits (74), Expect = 1.0
 Identities = 79/363 (21%), Positives = 139/363 (38%), Gaps = 50/363 (13%)

Query: 233 KSGGIPALVKMLGSPVDSVLFYAITTLHNLLL-HQEGAKMAVRLAGGLQKMVALLNKTNV 291
           K  GIP LV +L  P   V   A   L N+     +  K+A++   G+  +V LL K   
Sbjct: 305 KLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARD 364

Query: 292 KFLA--ITTDCLQILAYGNQESKLI-----------ILASGGPQALVNI---MRTYTYEK 335
             L   IT     + ++ + + +++           I+   G +   N     R   +E 
Sbjct: 365 MDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWES 424

Query: 336 LLWTTSRVLK-VLSVCSSNKPAIVEAGGMQALGLHLT-------DPSQRLVQNCLWTLRN 387
           +L  T+  L+ V S  S  +  + E  G+    + +        D   +LV+NC+  LRN
Sbjct: 425 VLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRN 484

Query: 388 LSDAATKQ----EGMEGLLGTLVQLLGSDDINVVTCAAGI----------LSNLTCNNYK 433
           LS    ++    E  +     +    G    +      G           + +   +   
Sbjct: 485 LSYQVHREIPQAERYQEAAPNVANNTGPHAASCFGAKKGKDEWFSRGKKPIEDPANDTVD 544

Query: 434 NKMMVCQVGGIEALVR--------TVLRAGDREDITEPAICALRHLTS-RHQEAEMAQNA 484
                    G E L +        ++L+      I E +  A+++L + R       ++A
Sbjct: 545 FPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSA 604

Query: 485 VRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAH 544
           +R    L  +  LL    H  ++KA  G +RNLA+  A +  L  + AIP LV+ L    
Sbjct: 605 LRQEKALSAIADLL-TNEHERVVKAASGALRNLAV-DARNKELIGKHAIPNLVKNLPGGQ 662

Query: 545 QDT 547
           Q++
Sbjct: 663 QNS 665


>gi|146231942 catenin, delta 1 isoform 1A [Homo sapiens]
          Length = 933

 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 71/284 (25%), Positives = 119/284 (41%), Gaps = 46/284 (16%)

Query: 221 LSHHREGLLAIFKS---GG----------IPALVKMLGSPVDSVLFYAITTLHNLLLHQE 267
           L+ H  G LA   S   GG          +P ++ MLG  +D+V   A   L +L    +
Sbjct: 339 LAQHERGSLASLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRND 398

Query: 268 GAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYG-NQESKLIILASGGPQALVN 326
             K  VR   G+  +V LL+    +        L+ +++G +Q++K+ I    G  ALV 
Sbjct: 399 KVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVR 458

Query: 327 IMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLH-LTDPSQRLVQNCLWTL 385
           ++R      L    +  L  LS   S K  IV+        LH LTD  + ++ +  W  
Sbjct: 459 LLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDH------ALHALTD--EVIIPHSGWER 510

Query: 386 RNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTC--NNYKNKMMVCQVGG 443
               D   +    E               +V+T  AG L N++   +  + K+  C  G 
Sbjct: 511 EPNEDCKPRHIEWE---------------SVLTNTAGCLRNVSSERSEARRKLRECD-GL 554

Query: 444 IEALVRTVLRAGDRED----ITEPAICALRHLTSR-HQEAEMAQ 482
           ++AL+  V     ++D    + E  +C LR+L+ + H+E   A+
Sbjct: 555 VDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAE 598



 Score = 37.4 bits (85), Expect = 0.054
 Identities = 94/427 (22%), Positives = 162/427 (37%), Gaps = 66/427 (15%)

Query: 153 IPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTN-DVETA 211
           +PE+  +L      V + AA  +  L  +       +R  + +  +V  + +   +V   
Sbjct: 368 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 427

Query: 212 RCTAGTLHNLSHHRE--GLLAIFKSGGIPALVKMLGSPVDSVLFYAIT-TLHNLLLHQEG 268
            C  G L N+S  R+    +AI    G+PALV++L    D  L   IT TL NL  H + 
Sbjct: 428 AC--GALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSH-DS 484

Query: 269 AKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVN-- 326
            KM +                +    A+T +              +I+   G +   N  
Sbjct: 485 IKMEI---------------VDHALHALTDE--------------VIIPHSGWEREPNED 515

Query: 327 -IMRTYTYEKLLWTTSRVLK-VLSVCSSNKPAIVEAGGMQALGLHLT-------DPSQRL 377
              R   +E +L  T+  L+ V S  S  +  + E  G+    + +        D   +L
Sbjct: 516 CKPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKL 575

Query: 378 VQNCLWTLRNLSDAATKQ----EGMEGLLGTLVQLLGSDDINVVTCAAG----ILSNLTC 429
           V+NC+  LRNLS    ++    E  +     +    G    +      G     + +   
Sbjct: 576 VENCVCLLRNLSYQVHREIPQAERYQEAAPNVANNTGPHAASCFGAKKGKGKKPIEDPAN 635

Query: 430 NNYKNKMMVCQVGGIEALVR--------TVLRAGDREDITEPAICALRHL-TSRHQEAEM 480
           +            G E L +        ++L+      I E +  A+++L   R      
Sbjct: 636 DTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRY 695

Query: 481 AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL 540
            ++A+R    L  +  LL    H  ++KA  G +RNLA+  A +  L  + AIP LV+ L
Sbjct: 696 IRSALRQEKALSAIADLL-TNEHERVVKAASGALRNLAV-DARNKELIGKHAIPNLVKNL 753

Query: 541 VRAHQDT 547
               Q++
Sbjct: 754 PGGQQNS 760


>gi|146231968 catenin, delta 1 isoform 1A [Homo sapiens]
          Length = 933

 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 71/284 (25%), Positives = 119/284 (41%), Gaps = 46/284 (16%)

Query: 221 LSHHREGLLAIFKS---GG----------IPALVKMLGSPVDSVLFYAITTLHNLLLHQE 267
           L+ H  G LA   S   GG          +P ++ MLG  +D+V   A   L +L    +
Sbjct: 339 LAQHERGSLASLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRND 398

Query: 268 GAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYG-NQESKLIILASGGPQALVN 326
             K  VR   G+  +V LL+    +        L+ +++G +Q++K+ I    G  ALV 
Sbjct: 399 KVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVR 458

Query: 327 IMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLH-LTDPSQRLVQNCLWTL 385
           ++R      L    +  L  LS   S K  IV+        LH LTD  + ++ +  W  
Sbjct: 459 LLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDH------ALHALTD--EVIIPHSGWER 510

Query: 386 RNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTC--NNYKNKMMVCQVGG 443
               D   +    E               +V+T  AG L N++   +  + K+  C  G 
Sbjct: 511 EPNEDCKPRHIEWE---------------SVLTNTAGCLRNVSSERSEARRKLRECD-GL 554

Query: 444 IEALVRTVLRAGDRED----ITEPAICALRHLTSR-HQEAEMAQ 482
           ++AL+  V     ++D    + E  +C LR+L+ + H+E   A+
Sbjct: 555 VDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAE 598



 Score = 37.4 bits (85), Expect = 0.054
 Identities = 94/427 (22%), Positives = 162/427 (37%), Gaps = 66/427 (15%)

Query: 153 IPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTN-DVETA 211
           +PE+  +L      V + AA  +  L  +       +R  + +  +V  + +   +V   
Sbjct: 368 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 427

Query: 212 RCTAGTLHNLSHHRE--GLLAIFKSGGIPALVKMLGSPVDSVLFYAIT-TLHNLLLHQEG 268
            C  G L N+S  R+    +AI    G+PALV++L    D  L   IT TL NL  H + 
Sbjct: 428 AC--GALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSH-DS 484

Query: 269 AKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVN-- 326
            KM +                +    A+T +              +I+   G +   N  
Sbjct: 485 IKMEI---------------VDHALHALTDE--------------VIIPHSGWEREPNED 515

Query: 327 -IMRTYTYEKLLWTTSRVLK-VLSVCSSNKPAIVEAGGMQALGLHLT-------DPSQRL 377
              R   +E +L  T+  L+ V S  S  +  + E  G+    + +        D   +L
Sbjct: 516 CKPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKL 575

Query: 378 VQNCLWTLRNLSDAATKQ----EGMEGLLGTLVQLLGSDDINVVTCAAG----ILSNLTC 429
           V+NC+  LRNLS    ++    E  +     +    G    +      G     + +   
Sbjct: 576 VENCVCLLRNLSYQVHREIPQAERYQEAAPNVANNTGPHAASCFGAKKGKGKKPIEDPAN 635

Query: 430 NNYKNKMMVCQVGGIEALVR--------TVLRAGDREDITEPAICALRHL-TSRHQEAEM 480
           +            G E L +        ++L+      I E +  A+++L   R      
Sbjct: 636 DTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRY 695

Query: 481 AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL 540
            ++A+R    L  +  LL    H  ++KA  G +RNLA+  A +  L  + AIP LV+ L
Sbjct: 696 IRSALRQEKALSAIADLL-TNEHERVVKAASGALRNLAV-DARNKELIGKHAIPNLVKNL 753

Query: 541 VRAHQDT 547
               Q++
Sbjct: 754 PGGQQNS 760


>gi|146231938 catenin, delta 1 isoform 1A [Homo sapiens]
          Length = 933

 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 71/284 (25%), Positives = 119/284 (41%), Gaps = 46/284 (16%)

Query: 221 LSHHREGLLAIFKS---GG----------IPALVKMLGSPVDSVLFYAITTLHNLLLHQE 267
           L+ H  G LA   S   GG          +P ++ MLG  +D+V   A   L +L    +
Sbjct: 339 LAQHERGSLASLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRND 398

Query: 268 GAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYG-NQESKLIILASGGPQALVN 326
             K  VR   G+  +V LL+    +        L+ +++G +Q++K+ I    G  ALV 
Sbjct: 399 KVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVR 458

Query: 327 IMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLH-LTDPSQRLVQNCLWTL 385
           ++R      L    +  L  LS   S K  IV+        LH LTD  + ++ +  W  
Sbjct: 459 LLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDH------ALHALTD--EVIIPHSGWER 510

Query: 386 RNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTC--NNYKNKMMVCQVGG 443
               D   +    E               +V+T  AG L N++   +  + K+  C  G 
Sbjct: 511 EPNEDCKPRHIEWE---------------SVLTNTAGCLRNVSSERSEARRKLRECD-GL 554

Query: 444 IEALVRTVLRAGDRED----ITEPAICALRHLTSR-HQEAEMAQ 482
           ++AL+  V     ++D    + E  +C LR+L+ + H+E   A+
Sbjct: 555 VDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAE 598



 Score = 37.4 bits (85), Expect = 0.054
 Identities = 94/427 (22%), Positives = 162/427 (37%), Gaps = 66/427 (15%)

Query: 153 IPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTN-DVETA 211
           +PE+  +L      V + AA  +  L  +       +R  + +  +V  + +   +V   
Sbjct: 368 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 427

Query: 212 RCTAGTLHNLSHHRE--GLLAIFKSGGIPALVKMLGSPVDSVLFYAIT-TLHNLLLHQEG 268
            C  G L N+S  R+    +AI    G+PALV++L    D  L   IT TL NL  H + 
Sbjct: 428 AC--GALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSH-DS 484

Query: 269 AKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVN-- 326
            KM +                +    A+T +              +I+   G +   N  
Sbjct: 485 IKMEI---------------VDHALHALTDE--------------VIIPHSGWEREPNED 515

Query: 327 -IMRTYTYEKLLWTTSRVLK-VLSVCSSNKPAIVEAGGMQALGLHLT-------DPSQRL 377
              R   +E +L  T+  L+ V S  S  +  + E  G+    + +        D   +L
Sbjct: 516 CKPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKL 575

Query: 378 VQNCLWTLRNLSDAATKQ----EGMEGLLGTLVQLLGSDDINVVTCAAG----ILSNLTC 429
           V+NC+  LRNLS    ++    E  +     +    G    +      G     + +   
Sbjct: 576 VENCVCLLRNLSYQVHREIPQAERYQEAAPNVANNTGPHAASCFGAKKGKGKKPIEDPAN 635

Query: 430 NNYKNKMMVCQVGGIEALVR--------TVLRAGDREDITEPAICALRHL-TSRHQEAEM 480
           +            G E L +        ++L+      I E +  A+++L   R      
Sbjct: 636 DTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRY 695

Query: 481 AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL 540
            ++A+R    L  +  LL    H  ++KA  G +RNLA+  A +  L  + AIP LV+ L
Sbjct: 696 IRSALRQEKALSAIADLL-TNEHERVVKAASGALRNLAV-DARNKELIGKHAIPNLVKNL 753

Query: 541 VRAHQDT 547
               Q++
Sbjct: 754 PGGQQNS 760


>gi|10835010 catenin, delta 1 isoform 1B [Homo sapiens]
          Length = 941

 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 71/284 (25%), Positives = 119/284 (41%), Gaps = 46/284 (16%)

Query: 221 LSHHREGLLAIFKS---GG----------IPALVKMLGSPVDSVLFYAITTLHNLLLHQE 267
           L+ H  G LA   S   GG          +P ++ MLG  +D+V   A   L +L    +
Sbjct: 339 LAQHERGSLASLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRND 398

Query: 268 GAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYG-NQESKLIILASGGPQALVN 326
             K  VR   G+  +V LL+    +        L+ +++G +Q++K+ I    G  ALV 
Sbjct: 399 KVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVR 458

Query: 327 IMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLH-LTDPSQRLVQNCLWTL 385
           ++R      L    +  L  LS   S K  IV+        LH LTD  + ++ +  W  
Sbjct: 459 LLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDH------ALHALTD--EVIIPHSGWER 510

Query: 386 RNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTC--NNYKNKMMVCQVGG 443
               D   +    E               +V+T  AG L N++   +  + K+  C  G 
Sbjct: 511 EPNEDCKPRHIEWE---------------SVLTNTAGCLRNVSSERSEARRKLRECD-GL 554

Query: 444 IEALVRTVLRAGDRED----ITEPAICALRHLTSR-HQEAEMAQ 482
           ++AL+  V     ++D    + E  +C LR+L+ + H+E   A+
Sbjct: 555 VDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAE 598



 Score = 37.4 bits (85), Expect = 0.054
 Identities = 94/427 (22%), Positives = 162/427 (37%), Gaps = 66/427 (15%)

Query: 153 IPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTN-DVETA 211
           +PE+  +L      V + AA  +  L  +       +R  + +  +V  + +   +V   
Sbjct: 368 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 427

Query: 212 RCTAGTLHNLSHHRE--GLLAIFKSGGIPALVKMLGSPVDSVLFYAIT-TLHNLLLHQEG 268
            C  G L N+S  R+    +AI    G+PALV++L    D  L   IT TL NL  H + 
Sbjct: 428 AC--GALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSH-DS 484

Query: 269 AKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVN-- 326
            KM +                +    A+T +              +I+   G +   N  
Sbjct: 485 IKMEI---------------VDHALHALTDE--------------VIIPHSGWEREPNED 515

Query: 327 -IMRTYTYEKLLWTTSRVLK-VLSVCSSNKPAIVEAGGMQALGLHLT-------DPSQRL 377
              R   +E +L  T+  L+ V S  S  +  + E  G+    + +        D   +L
Sbjct: 516 CKPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKL 575

Query: 378 VQNCLWTLRNLSDAATKQ----EGMEGLLGTLVQLLGSDDINVVTCAAG----ILSNLTC 429
           V+NC+  LRNLS    ++    E  +     +    G    +      G     + +   
Sbjct: 576 VENCVCLLRNLSYQVHREIPQAERYQEAAPNVANNTGPHAASCFGAKKGKGKKPIEDPAN 635

Query: 430 NNYKNKMMVCQVGGIEALVR--------TVLRAGDREDITEPAICALRHL-TSRHQEAEM 480
           +            G E L +        ++L+      I E +  A+++L   R      
Sbjct: 636 DTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRY 695

Query: 481 AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL 540
            ++A+R    L  +  LL    H  ++KA  G +RNLA+  A +  L  + AIP LV+ L
Sbjct: 696 IRSALRQEKALSAIADLL-TNEHERVVKAASGALRNLAV-DARNKELIGKHAIPNLVKNL 753

Query: 541 VRAHQDT 547
               Q++
Sbjct: 754 PGGQQNS 760


>gi|146231962 catenin, delta 1 isoform 1AB [Homo sapiens]
          Length = 962

 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 71/284 (25%), Positives = 119/284 (41%), Gaps = 46/284 (16%)

Query: 221 LSHHREGLLAIFKS---GG----------IPALVKMLGSPVDSVLFYAITTLHNLLLHQE 267
           L+ H  G LA   S   GG          +P ++ MLG  +D+V   A   L +L    +
Sbjct: 339 LAQHERGSLASLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRND 398

Query: 268 GAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYG-NQESKLIILASGGPQALVN 326
             K  VR   G+  +V LL+    +        L+ +++G +Q++K+ I    G  ALV 
Sbjct: 399 KVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVR 458

Query: 327 IMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLH-LTDPSQRLVQNCLWTL 385
           ++R      L    +  L  LS   S K  IV+        LH LTD  + ++ +  W  
Sbjct: 459 LLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDH------ALHALTD--EVIIPHSGWER 510

Query: 386 RNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTC--NNYKNKMMVCQVGG 443
               D   +    E               +V+T  AG L N++   +  + K+  C  G 
Sbjct: 511 EPNEDCKPRHIEWE---------------SVLTNTAGCLRNVSSERSEARRKLRECD-GL 554

Query: 444 IEALVRTVLRAGDRED----ITEPAICALRHLTSR-HQEAEMAQ 482
           ++AL+  V     ++D    + E  +C LR+L+ + H+E   A+
Sbjct: 555 VDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAE 598



 Score = 37.4 bits (85), Expect = 0.054
 Identities = 94/427 (22%), Positives = 162/427 (37%), Gaps = 66/427 (15%)

Query: 153 IPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTN-DVETA 211
           +PE+  +L      V + AA  +  L  +       +R  + +  +V  + +   +V   
Sbjct: 368 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 427

Query: 212 RCTAGTLHNLSHHRE--GLLAIFKSGGIPALVKMLGSPVDSVLFYAIT-TLHNLLLHQEG 268
            C  G L N+S  R+    +AI    G+PALV++L    D  L   IT TL NL  H + 
Sbjct: 428 AC--GALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSH-DS 484

Query: 269 AKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVN-- 326
            KM +                +    A+T +              +I+   G +   N  
Sbjct: 485 IKMEI---------------VDHALHALTDE--------------VIIPHSGWEREPNED 515

Query: 327 -IMRTYTYEKLLWTTSRVLK-VLSVCSSNKPAIVEAGGMQALGLHLT-------DPSQRL 377
              R   +E +L  T+  L+ V S  S  +  + E  G+    + +        D   +L
Sbjct: 516 CKPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKL 575

Query: 378 VQNCLWTLRNLSDAATKQ----EGMEGLLGTLVQLLGSDDINVVTCAAG----ILSNLTC 429
           V+NC+  LRNLS    ++    E  +     +    G    +      G     + +   
Sbjct: 576 VENCVCLLRNLSYQVHREIPQAERYQEAAPNVANNTGPHAASCFGAKKGKGKKPIEDPAN 635

Query: 430 NNYKNKMMVCQVGGIEALVR--------TVLRAGDREDITEPAICALRHL-TSRHQEAEM 480
           +            G E L +        ++L+      I E +  A+++L   R      
Sbjct: 636 DTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRY 695

Query: 481 AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL 540
            ++A+R    L  +  LL    H  ++KA  G +RNLA+  A +  L  + AIP LV+ L
Sbjct: 696 IRSALRQEKALSAIADLL-TNEHERVVKAASGALRNLAV-DARNKELIGKHAIPNLVKNL 753

Query: 541 VRAHQDT 547
               Q++
Sbjct: 754 PGGQQNS 760


>gi|146231940 catenin, delta 1 isoform 1ABC [Homo sapiens]
          Length = 968

 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 71/284 (25%), Positives = 119/284 (41%), Gaps = 46/284 (16%)

Query: 221 LSHHREGLLAIFKS---GG----------IPALVKMLGSPVDSVLFYAITTLHNLLLHQE 267
           L+ H  G LA   S   GG          +P ++ MLG  +D+V   A   L +L    +
Sbjct: 339 LAQHERGSLASLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRND 398

Query: 268 GAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYG-NQESKLIILASGGPQALVN 326
             K  VR   G+  +V LL+    +        L+ +++G +Q++K+ I    G  ALV 
Sbjct: 399 KVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVR 458

Query: 327 IMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLH-LTDPSQRLVQNCLWTL 385
           ++R      L    +  L  LS   S K  IV+        LH LTD  + ++ +  W  
Sbjct: 459 LLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDH------ALHALTD--EVIIPHSGWER 510

Query: 386 RNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTC--NNYKNKMMVCQVGG 443
               D   +    E               +V+T  AG L N++   +  + K+  C  G 
Sbjct: 511 EPNEDCKPRHIEWE---------------SVLTNTAGCLRNVSSERSEARRKLRECD-GL 554

Query: 444 IEALVRTVLRAGDRED----ITEPAICALRHLTSR-HQEAEMAQ 482
           ++AL+  V     ++D    + E  +C LR+L+ + H+E   A+
Sbjct: 555 VDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAE 598



 Score = 35.0 bits (79), Expect = 0.27
 Identities = 35/125 (28%), Positives = 56/125 (44%), Gaps = 7/125 (5%)

Query: 153 IPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTN-DVETA 211
           +PE+  +L      V + AA  +  L  +       +R  + +  +V  + +   +V   
Sbjct: 368 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 427

Query: 212 RCTAGTLHNLSHHRE--GLLAIFKSGGIPALVKMLGSPVDSVLFYAIT-TLHNLLLHQEG 268
            C  G L N+S  R+    +AI    G+PALV++L    D  L   IT TL NL  H + 
Sbjct: 428 AC--GALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSH-DS 484

Query: 269 AKMAV 273
            KM +
Sbjct: 485 IKMEI 489



 Score = 33.1 bits (74), Expect = 1.0
 Identities = 79/363 (21%), Positives = 139/363 (38%), Gaps = 50/363 (13%)

Query: 233 KSGGIPALVKMLGSPVDSVLFYAITTLHNLLL-HQEGAKMAVRLAGGLQKMVALLNKTNV 291
           K  GIP LV +L  P   V   A   L N+     +  K+A++   G+  +V LL K   
Sbjct: 406 KLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARD 465

Query: 292 KFLA--ITTDCLQILAYGNQESKLI-----------ILASGGPQALVNI---MRTYTYEK 335
             L   IT     + ++ + + +++           I+   G +   N     R   +E 
Sbjct: 466 MDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWES 525

Query: 336 LLWTTSRVLK-VLSVCSSNKPAIVEAGGMQALGLHLT-------DPSQRLVQNCLWTLRN 387
           +L  T+  L+ V S  S  +  + E  G+    + +        D   +LV+NC+  LRN
Sbjct: 526 VLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRN 585

Query: 388 LSDAATKQ----EGMEGLLGTLVQLLGSDDINVVTCAAGI----------LSNLTCNNYK 433
           LS    ++    E  +     +    G    +      G           + +   +   
Sbjct: 586 LSYQVHREIPQAERYQEAAPNVANNTGPHAASCFGAKKGKDEWFSRGKKPIEDPANDTVD 645

Query: 434 NKMMVCQVGGIEALVR--------TVLRAGDREDITEPAICALRHLTS-RHQEAEMAQNA 484
                    G E L +        ++L+      I E +  A+++L + R       ++A
Sbjct: 646 FPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSA 705

Query: 485 VRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAH 544
           +R    L  +  LL    H  ++KA  G +RNLA+  A +  L  + AIP LV+ L    
Sbjct: 706 LRQEKALSAIADLL-TNEHERVVKAASGALRNLAV-DARNKELIGKHAIPNLVKNLPGGQ 763

Query: 545 QDT 547
           Q++
Sbjct: 764 QNS 766


>gi|91206450 ankyrin and armadillo repeat containing [Homo sapiens]
          Length = 1363

 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 81/370 (21%), Positives = 155/370 (41%), Gaps = 21/370 (5%)

Query: 153  IPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETAR 212
            IP L  LL      +  K   ++  +S  +++ HA++ +  + S I   + +  +V + R
Sbjct: 673  IPALINLLKSSKIKLQCKTVGLLSNISTHKSAVHALVEAGGIPSLINLLVCDEPEVHS-R 731

Query: 213  CTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMA 272
            C A  L++++   E    I K  GIP+L+ +L   +++VL   +  +  L +  E  + A
Sbjct: 732  C-AVILYDIAQC-ENKDVIAKYNGIPSLINLLNLNIENVLVNVMNCIRVLCIGNENNQRA 789

Query: 273  VRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYT 332
            VR   GL  ++  L+  +    A+++  +  +   N+E +  I   G    LV + +   
Sbjct: 790  VREHKGLPYLIRFLSSDSDVLKAVSSAAIAEVGRDNKEIQDAIAMEGAIPPLVALFKG-- 847

Query: 333  YEKLLWTTSRVLKVLSVCSSN---KPAIVEAGGMQALGLHLTDPSQRLVQN----CLWTL 385
             +++       + V S+ S N   + A +E    + L L L    Q  V+      LW L
Sbjct: 848  -KQISVQMKGAMAVESLASHNALIQKAFLEKSLTKYL-LKLLKAFQIDVKEQGAVALWAL 905

Query: 386  RNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIE 445
               +    K    +     ++ +L S    +       +  L+ ++  ++  +C+  GI 
Sbjct: 906  AGQTLKQQKYMAEQIGYSFIINMLLSPSAKMQYVGGEAVIALSKDSRMHQNQICEGNGIA 965

Query: 446  ALVRTVLRAGDREDITEPAICALRHLT--SRHQEAEMAQNAVRLHYGLPVVVKLL--HPP 501
             LVR +  +   E      I A+  +     H    ++Q  V      PV+++LL  HP 
Sbjct: 966  PLVRLLRISTIAEGTLLSVIRAVGSICIGVAHTSNPVSQQFVVDENAFPVLIQLLRNHPS 1025

Query: 502  SHWPLIKATV 511
               P IK  V
Sbjct: 1026 ---PNIKVEV 1032



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 48/214 (22%), Positives = 87/214 (40%), Gaps = 21/214 (9%)

Query: 491 LPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRR 550
           +P ++ LL   S   L   TVGL+ N++   +    L E G IP L+ LLV    +   R
Sbjct: 673 IPALINLLKS-SKIKLQCKTVGLLSNISTHKSAVHALVEAGGIPSLINLLVCDEPEVHSR 731

Query: 551 TSM------------------GGTQQQFVEGVRMEEIVEGCTGALHILA-RDVHNRIVIR 591
            ++                  G      +  + +E ++      + +L   + +N+  +R
Sbjct: 732 CAVILYDIAQCENKDVIAKYNGIPSLINLLNLNIENVLVNVMNCIRVLCIGNENNQRAVR 791

Query: 592 GLNTIPLFVQLLYSPIENIQRVAAGVLCELAQD-KEAAEAIEAEGATAPLTELLHSRNEG 650
               +P  ++ L S  + ++ V++  + E+ +D KE  +AI  EGA  PL  L   +   
Sbjct: 792 EHKGLPYLIRFLSSDSDVLKAVSSAAIAEVGRDNKEIQDAIAMEGAIPPLVALFKGKQIS 851

Query: 651 VATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFR 684
           V    A  +  ++       K  L   LT  L +
Sbjct: 852 VQMKGAMAVESLASHNALIQKAFLEKSLTKYLLK 885



 Score = 33.5 bits (75), Expect = 0.78
 Identities = 24/90 (26%), Positives = 41/90 (45%), Gaps = 1/90 (1%)

Query: 580 LARDVHNRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAP 639
           LA D + R ++    TIP  + LL S    +Q    G+L  ++  K A  A+   G    
Sbjct: 658 LANDQYWRCILDA-GTIPALINLLKSSKIKLQCKTVGLLSNISTHKSAVHALVEAGGIPS 716

Query: 640 LTELLHSRNEGVATYAAAVLFRMSEDKPQD 669
           L  LL      V +  A +L+ +++ + +D
Sbjct: 717 LINLLVCDEPEVHSRCAVILYDIAQCENKD 746



 Score = 30.4 bits (67), Expect = 6.6
 Identities = 33/142 (23%), Positives = 63/142 (44%), Gaps = 10/142 (7%)

Query: 400 GLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDRED 459
           G +  L+ LL S  I +     G+LSN++ +      +V + GGI +L+   L   D  +
Sbjct: 671 GTIPALINLLKSSKIKLQCKTVGLLSNISTHKSAVHALV-EAGGIPSLIN--LLVCDEPE 727

Query: 460 ITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLAL 519
           +       L  +     +  +A+     + G+P ++ LL+      L+   +  IR L +
Sbjct: 728 VHSRCAVILYDIAQCENKDVIAK-----YNGIPSLINLLNLNIENVLVN-VMNCIRVLCI 781

Query: 520 CPANH-APLREQGAIPRLVQLL 540
              N+   +RE   +P L++ L
Sbjct: 782 GNENNQRAVREHKGLPYLIRFL 803


>gi|53829376 plakophilin 4 isoform b [Homo sapiens]
          Length = 1149

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 104/471 (22%), Positives = 180/471 (38%), Gaps = 84/471 (17%)

Query: 237 IPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAI 296
           +P ++ ML     SV   A   L +L       KM V   GG++ +V LL+   ++    
Sbjct: 530 LPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVCRLGGIKHLVDLLDHRVLEVQKN 589

Query: 297 TTDCLQILAYGNQ--ESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNK 354
               L+ L +G    E+K+ +   GG  AL+ ++R     ++    + VL  LS C + K
Sbjct: 590 ACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSSCDAVK 649

Query: 355 PAIVEAGGMQALGLHLTDP------------------SQRLVQNCLWTLRNLSDA---AT 393
             I+    +  L   +  P                  +  +++N    LRNLS A   A 
Sbjct: 650 MTIIR-DALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVLRNTTGCLRNLSSAGEEAR 708

Query: 394 KQ-EGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCN----NYKNKMMVCQVG--GIEA 446
           KQ    EGL+ +L+ ++ +  +N     +  + N  C     +Y+ ++ V Q    G+  
Sbjct: 709 KQMRSCEGLVDSLLYVIHT-CVNTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGLNE 767

Query: 447 LVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGL------------PVV 494
           L   + +    +D +EP+    +    +    E   + V    GL            P V
Sbjct: 768 LDDLLGKESPSKD-SEPSCWGKKKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHPSV 826

Query: 495 VK----LLHPPSHWPLIKATVGLIRNLA-----LCPANHAPLREQGAIPRLVQLLVRAHQ 545
           VK    LL   S+   ++ + G ++NL+           A +R++  +P LV+LL     
Sbjct: 827 VKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAVRKEKGLPILVELL---RM 883

Query: 546 DTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLL-- 603
           D  R                   +V     AL  +A DV N+ +I G   +   V  L  
Sbjct: 884 DNDR-------------------VVSSVATALRNMALDVRNKELI-GKYAMRDLVNRLPG 923

Query: 604 -YSPIENIQRVAAGVLCEL----AQDKEAAEAIEAEGATAPLTELLHSRNE 649
              P        A + C L    +++ E A+A+   G    L  +   R +
Sbjct: 924 GNGPSVLSDETMAAICCALHEVTSKNMENAKALADSGGIEKLVNITKGRGD 974



 Score = 36.2 bits (82), Expect = 0.12
 Identities = 93/434 (21%), Positives = 162/434 (37%), Gaps = 107/434 (24%)

Query: 143 QDDAELATR--AIPELTKLLNDE-DQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIV 199
           +D  E A R   +PE+  +L  +   V  N AA + H        +  + R   +   + 
Sbjct: 518 KDPREFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVCRLGGIKHLVD 577

Query: 200 RTMQNTNDVETARCTAGTLHNLSHHR---EGLLAIFKSGGIPALVKMLGSPVDSVLFYAI 256
                  +V+   C  G L NL   +   E  +A+   GGIPAL+++L   +D+ +   +
Sbjct: 578 LLDHRVLEVQKNAC--GALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELV 635

Query: 257 TTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKT-----------------NVKF-----L 294
           T +   L   +  KM +     ++  ++ L  T                  +KF     L
Sbjct: 636 TGVLWNLSSCDAVKMTI-----IRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVL 690

Query: 295 AITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNK 354
             TT CL+ L+   +E++  + +  G                      +L V+  C    
Sbjct: 691 RNTTGCLRNLSSAGEEARKQMRSCEG------------------LVDSLLYVIHTC---- 728

Query: 355 PAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLG--TLVQLLGSD 412
                        ++ +D   + V+NC+ TLRNLS     +     LLG   L  LLG +
Sbjct: 729 -------------VNTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGLNELDDLLGKE 775

Query: 413 DINVVTCAAGILSNLTC--NNYKNKMMVCQ------VGGIEALVR--------------- 449
                  +    S  +C     K K    Q      VG I  L +               
Sbjct: 776 -------SPSKDSEPSCWGKKKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHPSVVK 828

Query: 450 ---TVLRAGDREDITEPAICALRHLTSRHQE-AEMAQNAVRLHYGLPVVVKLLHPPSHWP 505
              T+L         E +  +L++L++ + + A   + AVR   GLP++V+LL   +   
Sbjct: 829 PYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAVRKEKGLPILVELLRMDND-R 887

Query: 506 LIKATVGLIRNLAL 519
           ++ +    +RN+AL
Sbjct: 888 VVSSVATALRNMAL 901



 Score = 36.2 bits (82), Expect = 0.12
 Identities = 40/152 (26%), Positives = 64/152 (42%), Gaps = 19/152 (12%)

Query: 192 PQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGL-----LAIFKSGGIPALVKMLGS 246
           P +V   +  +  +++  T   +AG+L NLS            A+ K  G+P LV++L  
Sbjct: 824 PSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAVRKEKGLPILVELLRM 883

Query: 247 PVDSVLFYAITTLHNLLLHQEGAK---------MAVRLAGGLQKMVALLNKTNVKFLAIT 297
             D V+    T L N+ L     +         +  RL GG    V L ++T    +A  
Sbjct: 884 DNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGGNGPSV-LSDET----MAAI 938

Query: 298 TDCLQILAYGNQESKLIILASGGPQALVNIMR 329
              L  +   N E+   +  SGG + LVNI +
Sbjct: 939 CCALHEVTSKNMENAKALADSGGIEKLVNITK 970



 Score = 31.2 bits (69), Expect = 3.9
 Identities = 31/116 (26%), Positives = 47/116 (40%), Gaps = 11/116 (9%)

Query: 354 KPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQE-----GMEGLLGTLVQL 408
           + A+ +  G+  L   L   + R+V +    LRN++     +E      M  L+  L   
Sbjct: 865 RAAVRKEKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGG 924

Query: 409 LG----SDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDI 460
            G    SD+     C A  L  +T  N +N   +   GGIE LV      GDR  +
Sbjct: 925 NGPSVLSDETMAAICCA--LHEVTSKNMENAKALADSGGIEKLVNITKGRGDRSSL 978


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.132    0.384 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,454,699
Number of Sequences: 37866
Number of extensions: 1232500
Number of successful extensions: 3317
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 51
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 2942
Number of HSP's gapped (non-prelim): 243
length of query: 781
length of database: 18,247,518
effective HSP length: 110
effective length of query: 671
effective length of database: 14,082,258
effective search space: 9449195118
effective search space used: 9449195118
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.