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Search of human proteins with 42718017
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|42718017 retinoblastoma binding protein 8 isoform b [Homo
sapiens]
(867 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|42718017 retinoblastoma binding protein 8 isoform b [Homo sap... 1734 0.0
gi|42718015 retinoblastoma binding protein 8 isoform a [Homo sap... 1573 0.0
gi|4506441 retinoblastoma binding protein 8 isoform a [Homo sapi... 1573 0.0
gi|24308394 hypothetical protein LOC140893 [Homo sapiens] 138 3e-32
gi|115511012 coiled-coil domain containing 136 [Homo sapiens] 54 5e-07
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 53 1e-06
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 53 1e-06
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 53 1e-06
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 53 1e-06
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 53 1e-06
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 53 1e-06
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 53 1e-06
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 53 1e-06
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 53 1e-06
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 52 2e-06
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 49 3e-05
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 46 1e-04
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 46 1e-04
gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo sapi... 45 2e-04
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 45 3e-04
gi|149999352 forkhead box P2 isoform II [Homo sapiens] 45 4e-04
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 45 4e-04
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 45 4e-04
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 45 4e-04
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 45 4e-04
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 44 5e-04
gi|59806361 hypothetical protein LOC387104 [Homo sapiens] 44 5e-04
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 44 5e-04
gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo sap... 44 6e-04
gi|17017963 forkhead box P2 isoform I [Homo sapiens] 44 6e-04
>gi|42718017 retinoblastoma binding protein 8 isoform b [Homo
sapiens]
Length = 867
Score = 1734 bits (4490), Expect = 0.0
Identities = 867/867 (100%), Positives = 867/867 (100%)
Query: 1 MNISGSSCGSPNSADTSSDFKDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFF 60
MNISGSSCGSPNSADTSSDFKDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFF
Sbjct: 1 MNISGSSCGSPNSADTSSDFKDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFF 60
Query: 61 TKNQQLREQQKVLHETIKVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITEL 120
TKNQQLREQQKVLHETIKVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITEL
Sbjct: 61 TKNQQLREQQKVLHETIKVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITEL 120
Query: 121 MNERNTLQEENKKLSEQLQQKIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRRKE 180
MNERNTLQEENKKLSEQLQQKIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRRKE
Sbjct: 121 MNERNTLQEENKKLSEQLQQKIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRRKE 180
Query: 181 NPHVRYIEQTHTKLEHSVCANEMRKVSKSSTHPQHNPNENEILVADTYDQSQSPMAKAHG 240
NPHVRYIEQTHTKLEHSVCANEMRKVSKSSTHPQHNPNENEILVADTYDQSQSPMAKAHG
Sbjct: 181 NPHVRYIEQTHTKLEHSVCANEMRKVSKSSTHPQHNPNENEILVADTYDQSQSPMAKAHG 240
Query: 241 TSSYTPDKSSFNLATVVAETLGLGVQEESETQGPMSPLGDELYHCLEGNHKKQPFEESTR 300
TSSYTPDKSSFNLATVVAETLGLGVQEESETQGPMSPLGDELYHCLEGNHKKQPFEESTR
Sbjct: 241 TSSYTPDKSSFNLATVVAETLGLGVQEESETQGPMSPLGDELYHCLEGNHKKQPFEESTR 300
Query: 301 NTEDSLRFSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDLNTSLSPSLLQPGKKKHLK 360
NTEDSLRFSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDLNTSLSPSLLQPGKKKHLK
Sbjct: 301 NTEDSLRFSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDLNTSLSPSLLQPGKKKHLK 360
Query: 361 TLPFSNTCISRLEKTRSKSEDSALFTHHSLGSEVNKIIIQSSNKQILINKNISESLGEQN 420
TLPFSNTCISRLEKTRSKSEDSALFTHHSLGSEVNKIIIQSSNKQILINKNISESLGEQN
Sbjct: 361 TLPFSNTCISRLEKTRSKSEDSALFTHHSLGSEVNKIIIQSSNKQILINKNISESLGEQN 420
Query: 421 RTEYGKDSNTDKHLEPLKSLGGRTSKRKKTEEESEHEVSCPQASFDKENAFPFPMDNQFS 480
RTEYGKDSNTDKHLEPLKSLGGRTSKRKKTEEESEHEVSCPQASFDKENAFPFPMDNQFS
Sbjct: 421 RTEYGKDSNTDKHLEPLKSLGGRTSKRKKTEEESEHEVSCPQASFDKENAFPFPMDNQFS 480
Query: 481 MNGDCVMDKPLDLSDRFSAIQRQEKSQGSETSKNKFRQVTLYEALKTIPKGFSSSRKASD 540
MNGDCVMDKPLDLSDRFSAIQRQEKSQGSETSKNKFRQVTLYEALKTIPKGFSSSRKASD
Sbjct: 481 MNGDCVMDKPLDLSDRFSAIQRQEKSQGSETSKNKFRQVTLYEALKTIPKGFSSSRKASD 540
Query: 541 GNCTLPKDSPGEPCSQECIILQPLNKCSPDNKPSLQIKEENAVFKIPLRPRESLETENVL 600
GNCTLPKDSPGEPCSQECIILQPLNKCSPDNKPSLQIKEENAVFKIPLRPRESLETENVL
Sbjct: 541 GNCTLPKDSPGEPCSQECIILQPLNKCSPDNKPSLQIKEENAVFKIPLRPRESLETENVL 600
Query: 601 DDIKSAGSHEPIKIQTRSDHGGCELASVLQLNPCRTGKIKSLQNNQDVSFENIQWSIDPG 660
DDIKSAGSHEPIKIQTRSDHGGCELASVLQLNPCRTGKIKSLQNNQDVSFENIQWSIDPG
Sbjct: 601 DDIKSAGSHEPIKIQTRSDHGGCELASVLQLNPCRTGKIKSLQNNQDVSFENIQWSIDPG 660
Query: 661 ADLSQYKMDVTVIDTKDGSQSKLGGETVDMDCTLVSETVLLKMKKQEQKGEKSSNEERKM 720
ADLSQYKMDVTVIDTKDGSQSKLGGETVDMDCTLVSETVLLKMKKQEQKGEKSSNEERKM
Sbjct: 661 ADLSQYKMDVTVIDTKDGSQSKLGGETVDMDCTLVSETVLLKMKKQEQKGEKSSNEERKM 720
Query: 721 NDSLEDMFDRTTHEEYESCLADSFSQAADEEEELSTATKKLHTHGDKQDKVKQKAFVEPY 780
NDSLEDMFDRTTHEEYESCLADSFSQAADEEEELSTATKKLHTHGDKQDKVKQKAFVEPY
Sbjct: 721 NDSLEDMFDRTTHEEYESCLADSFSQAADEEEELSTATKKLHTHGDKQDKVKQKAFVEPY 780
Query: 781 FKGDESIMQICQQKKEKRNWLPAQDTDSATFHPTHQRIFGKLVFLPLRLVWKEVILRKIL 840
FKGDESIMQICQQKKEKRNWLPAQDTDSATFHPTHQRIFGKLVFLPLRLVWKEVILRKIL
Sbjct: 781 FKGDESIMQICQQKKEKRNWLPAQDTDSATFHPTHQRIFGKLVFLPLRLVWKEVILRKIL 840
Query: 841 ILVLVQKDVSLTTQYFLQKARSRRHRR 867
ILVLVQKDVSLTTQYFLQKARSRRHRR
Sbjct: 841 ILVLVQKDVSLTTQYFLQKARSRRHRR 867
>gi|42718015 retinoblastoma binding protein 8 isoform a [Homo
sapiens]
Length = 897
Score = 1573 bits (4072), Expect = 0.0
Identities = 789/809 (97%), Positives = 796/809 (98%), Gaps = 8/809 (0%)
Query: 1 MNISGSSCGSPNSADTSSDFKDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFF 60
MNISGSSCGSPNSADTSSDFKDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFF
Sbjct: 1 MNISGSSCGSPNSADTSSDFKDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFF 60
Query: 61 TKNQQLREQQKVLHETIKVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITEL 120
TKNQQLREQQKVLHETIKVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITEL
Sbjct: 61 TKNQQLREQQKVLHETIKVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITEL 120
Query: 121 MNERNTLQEENKKLSEQLQQKIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRRKE 180
MNERNTLQEENKKLSEQLQQKIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRRKE
Sbjct: 121 MNERNTLQEENKKLSEQLQQKIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRRKE 180
Query: 181 NPHVRYIEQTHTKLEHSVCANEMRKVSKSSTHPQHNPNENEILVADTYDQSQSPMAKAHG 240
NPHVRYIEQTHTKLEHSVCANEMRKVSKSSTHPQHNPNENEILVADTYDQSQSPMAKAHG
Sbjct: 181 NPHVRYIEQTHTKLEHSVCANEMRKVSKSSTHPQHNPNENEILVADTYDQSQSPMAKAHG 240
Query: 241 TSSYTPDKSSFNLATVVAETLGLGVQEESETQGPMSPLGDELYHCLEGNHKKQPFEESTR 300
TSSYTPDKSSFNLATVVAETLGLGVQEESETQGPMSPLGDELYHCLEGNHKKQPFEESTR
Sbjct: 241 TSSYTPDKSSFNLATVVAETLGLGVQEESETQGPMSPLGDELYHCLEGNHKKQPFEESTR 300
Query: 301 NTEDSLRFSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDLNTSLSPSLLQPGKKKHLK 360
NTEDSLRFSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDLNTSLSPSLLQPGKKKHLK
Sbjct: 301 NTEDSLRFSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDLNTSLSPSLLQPGKKKHLK 360
Query: 361 TLPFSNTCISRLEKTRSKSEDSALFTHHSLGSEVNKIIIQSSNKQILINKNISESLGEQN 420
TLPFSNTCISRLEKTRSKSEDSALFTHHSLGSEVNKIIIQSSNKQILINKNISESLGEQN
Sbjct: 361 TLPFSNTCISRLEKTRSKSEDSALFTHHSLGSEVNKIIIQSSNKQILINKNISESLGEQN 420
Query: 421 RTEYGKDSNTDKHLEPLKSLGGRTSKRKKTEEESEHEVSCPQASFDKENAFPFPMDNQFS 480
RTEYGKDSNTDKHLEPLKSLGGRTSKRKKTEEESEHEVSCPQASFDKENAFPFPMDNQFS
Sbjct: 421 RTEYGKDSNTDKHLEPLKSLGGRTSKRKKTEEESEHEVSCPQASFDKENAFPFPMDNQFS 480
Query: 481 MNGDCVMDKPLDLSDRFSAIQRQEKSQGSETSKNKFRQVTLYEALKTIPKGFSSSRKASD 540
MNGDCVMDKPLDLSDRFSAIQRQEKSQGSETSKNKFRQVTLYEALKTIPKGFSSSRKASD
Sbjct: 481 MNGDCVMDKPLDLSDRFSAIQRQEKSQGSETSKNKFRQVTLYEALKTIPKGFSSSRKASD 540
Query: 541 GNCTLPKDSPGEPCSQECIILQPLNKCSPDNKPSLQIKEENAVFKIPLRPRESLETENVL 600
GNCTLPKDSPGEPCSQECIILQPLNKCSPDNKPSLQIKEENAVFKIPLRPRESLETENVL
Sbjct: 541 GNCTLPKDSPGEPCSQECIILQPLNKCSPDNKPSLQIKEENAVFKIPLRPRESLETENVL 600
Query: 601 DDIKSAGSHEPIKIQTRSDHGGCELASVLQLNPCRTGKIKSLQNNQDVSFENIQWSIDPG 660
DDIKSAGSHEPIKIQTRSDHGGCELASVLQLNPCRTGKIKSLQNNQDVSFENIQWSIDPG
Sbjct: 601 DDIKSAGSHEPIKIQTRSDHGGCELASVLQLNPCRTGKIKSLQNNQDVSFENIQWSIDPG 660
Query: 661 ADLSQYKMDVTVIDTKDGSQSKLGGETVDMDCTLVSETVLLKMKKQEQKGEKSSNEERKM 720
ADLSQYKMDVTVIDTKDGSQSKLGGETVDMDCTLVSETVLLKMKKQEQKGEKSSNEERKM
Sbjct: 661 ADLSQYKMDVTVIDTKDGSQSKLGGETVDMDCTLVSETVLLKMKKQEQKGEKSSNEERKM 720
Query: 721 NDSLEDMFDRTTHEEYESCLADSFSQAADEEEELSTATKKLHTHGDKQDKVKQKAFVEPY 780
NDSLEDMFDRTTHEEYESCLADSFSQAADEEEELSTATKKLHTHGDKQDKVKQKAFVEPY
Sbjct: 721 NDSLEDMFDRTTHEEYESCLADSFSQAADEEEELSTATKKLHTHGDKQDKVKQKAFVEPY 780
Query: 781 FKGDE--------SIMQICQQKKEKRNWL 801
FKGDE +++ ++K+E+R L
Sbjct: 781 FKGDERETSLQNFPHIEVVRKKEERRKLL 809
>gi|4506441 retinoblastoma binding protein 8 isoform a [Homo
sapiens]
Length = 897
Score = 1573 bits (4072), Expect = 0.0
Identities = 789/809 (97%), Positives = 796/809 (98%), Gaps = 8/809 (0%)
Query: 1 MNISGSSCGSPNSADTSSDFKDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFF 60
MNISGSSCGSPNSADTSSDFKDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFF
Sbjct: 1 MNISGSSCGSPNSADTSSDFKDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFF 60
Query: 61 TKNQQLREQQKVLHETIKVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITEL 120
TKNQQLREQQKVLHETIKVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITEL
Sbjct: 61 TKNQQLREQQKVLHETIKVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITEL 120
Query: 121 MNERNTLQEENKKLSEQLQQKIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRRKE 180
MNERNTLQEENKKLSEQLQQKIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRRKE
Sbjct: 121 MNERNTLQEENKKLSEQLQQKIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRRKE 180
Query: 181 NPHVRYIEQTHTKLEHSVCANEMRKVSKSSTHPQHNPNENEILVADTYDQSQSPMAKAHG 240
NPHVRYIEQTHTKLEHSVCANEMRKVSKSSTHPQHNPNENEILVADTYDQSQSPMAKAHG
Sbjct: 181 NPHVRYIEQTHTKLEHSVCANEMRKVSKSSTHPQHNPNENEILVADTYDQSQSPMAKAHG 240
Query: 241 TSSYTPDKSSFNLATVVAETLGLGVQEESETQGPMSPLGDELYHCLEGNHKKQPFEESTR 300
TSSYTPDKSSFNLATVVAETLGLGVQEESETQGPMSPLGDELYHCLEGNHKKQPFEESTR
Sbjct: 241 TSSYTPDKSSFNLATVVAETLGLGVQEESETQGPMSPLGDELYHCLEGNHKKQPFEESTR 300
Query: 301 NTEDSLRFSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDLNTSLSPSLLQPGKKKHLK 360
NTEDSLRFSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDLNTSLSPSLLQPGKKKHLK
Sbjct: 301 NTEDSLRFSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDLNTSLSPSLLQPGKKKHLK 360
Query: 361 TLPFSNTCISRLEKTRSKSEDSALFTHHSLGSEVNKIIIQSSNKQILINKNISESLGEQN 420
TLPFSNTCISRLEKTRSKSEDSALFTHHSLGSEVNKIIIQSSNKQILINKNISESLGEQN
Sbjct: 361 TLPFSNTCISRLEKTRSKSEDSALFTHHSLGSEVNKIIIQSSNKQILINKNISESLGEQN 420
Query: 421 RTEYGKDSNTDKHLEPLKSLGGRTSKRKKTEEESEHEVSCPQASFDKENAFPFPMDNQFS 480
RTEYGKDSNTDKHLEPLKSLGGRTSKRKKTEEESEHEVSCPQASFDKENAFPFPMDNQFS
Sbjct: 421 RTEYGKDSNTDKHLEPLKSLGGRTSKRKKTEEESEHEVSCPQASFDKENAFPFPMDNQFS 480
Query: 481 MNGDCVMDKPLDLSDRFSAIQRQEKSQGSETSKNKFRQVTLYEALKTIPKGFSSSRKASD 540
MNGDCVMDKPLDLSDRFSAIQRQEKSQGSETSKNKFRQVTLYEALKTIPKGFSSSRKASD
Sbjct: 481 MNGDCVMDKPLDLSDRFSAIQRQEKSQGSETSKNKFRQVTLYEALKTIPKGFSSSRKASD 540
Query: 541 GNCTLPKDSPGEPCSQECIILQPLNKCSPDNKPSLQIKEENAVFKIPLRPRESLETENVL 600
GNCTLPKDSPGEPCSQECIILQPLNKCSPDNKPSLQIKEENAVFKIPLRPRESLETENVL
Sbjct: 541 GNCTLPKDSPGEPCSQECIILQPLNKCSPDNKPSLQIKEENAVFKIPLRPRESLETENVL 600
Query: 601 DDIKSAGSHEPIKIQTRSDHGGCELASVLQLNPCRTGKIKSLQNNQDVSFENIQWSIDPG 660
DDIKSAGSHEPIKIQTRSDHGGCELASVLQLNPCRTGKIKSLQNNQDVSFENIQWSIDPG
Sbjct: 601 DDIKSAGSHEPIKIQTRSDHGGCELASVLQLNPCRTGKIKSLQNNQDVSFENIQWSIDPG 660
Query: 661 ADLSQYKMDVTVIDTKDGSQSKLGGETVDMDCTLVSETVLLKMKKQEQKGEKSSNEERKM 720
ADLSQYKMDVTVIDTKDGSQSKLGGETVDMDCTLVSETVLLKMKKQEQKGEKSSNEERKM
Sbjct: 661 ADLSQYKMDVTVIDTKDGSQSKLGGETVDMDCTLVSETVLLKMKKQEQKGEKSSNEERKM 720
Query: 721 NDSLEDMFDRTTHEEYESCLADSFSQAADEEEELSTATKKLHTHGDKQDKVKQKAFVEPY 780
NDSLEDMFDRTTHEEYESCLADSFSQAADEEEELSTATKKLHTHGDKQDKVKQKAFVEPY
Sbjct: 721 NDSLEDMFDRTTHEEYESCLADSFSQAADEEEELSTATKKLHTHGDKQDKVKQKAFVEPY 780
Query: 781 FKGDE--------SIMQICQQKKEKRNWL 801
FKGDE +++ ++K+E+R L
Sbjct: 781 FKGDERETSLQNFPHIEVVRKKEERRKLL 809
>gi|24308394 hypothetical protein LOC140893 [Homo sapiens]
Length = 664
Score = 138 bits (347), Expect = 3e-32
Identities = 80/173 (46%), Positives = 108/173 (62%), Gaps = 4/173 (2%)
Query: 20 FKDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQQKVLHETIKV 79
F + +LKE H++EV GLQ K+ +L ER DAQR+EE F+KN QLREQQK L E ++V
Sbjct: 4 FMESLNRLKEIHEKEVLGLQNKLLELNSERCRDAQRIEELFSKNHQLREQQKTLKENLRV 63
Query: 80 LEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQ 139
LE+RLRAGLCDRC VT+E RK+QQEFE+ QNL+ I L NE N L+EEN+ L E+++
Sbjct: 64 LENRLRAGLCDRCMVTQELARKRQQEFESSHLQNLQRIFILTNEMNGLKEENETLKEEVK 123
Query: 140 Q-KIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRRKENPHVRYIEQTH 191
+ ++ D+ A+ E P SP+ S G + K E+ H
Sbjct: 124 RLRVLGDRPKPRAK---EGTSDPPSPLLLPSPGGWKAITEKPPGGHEEAEEDH 173
>gi|115511012 coiled-coil domain containing 136 [Homo sapiens]
Length = 1154
Score = 54.3 bits (129), Expect = 5e-07
Identities = 110/506 (21%), Positives = 195/506 (38%), Gaps = 73/506 (14%)
Query: 34 EVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQQKVLHETIKVLEDRLRAGLCDRCA 93
E+QGL L+ ER+ AQ+ E F + QQL+ + + L E I +LE + L +
Sbjct: 88 ELQGL------LEDERLASAQQAEVFTKQIQQLQGELRSLREEISLLEHEKESELKE--- 138
Query: 94 VTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQ--QKIENDQQHQAA 151
E+ + Q E +++RQ TE ++ +LQE+ ++ +L+ ++I D + + A
Sbjct: 139 -IEQELHLAQAEIQSLRQAAEDSATEHESDIASLQEDLCRMQNELEDMERIRGDYEMEIA 197
Query: 152 ELECEEDV---IPDSPITAFSFSGVNRLRRKENPHVRYIEQTHTKLEHSVCANEMRKVSK 208
L E ++ P + +SG+ ++ ++ + + L+ S
Sbjct: 198 SLRAEMEMKSSEPSGSLGLSDYSGLQEELQELRERYHFLNEEYRALQE----------SN 247
Query: 209 SSTHPQHNPNENEILVADTYDQSQSPMAKAHGTSSYTPDKSSFNLATVVAETLGLGVQEE 268
SS Q E+E T QS S T + F + L +++
Sbjct: 248 SSLTGQLADLESERTQRATERWLQSQTLSMTSAESQT-SEMDFLEPDPEMQLLRQQLRDA 306
Query: 269 SETQGPMSPLGDELYHCLEG-NHKKQPFEESTRNTE--------DSLRFSDSTSKTPPQE 319
E M EL LE H +Q EE R + + LRF S S T E
Sbjct: 307 EEQMHGMKNKCQELCCELEELQHHRQVSEEEQRRLQRELKCAQNEVLRFQTSHSVT-QNE 365
Query: 320 ELPTRVSSPVFGATSS-------IKSGLDLNTSLSPSLLQPGKKKHLKTLPFSNTCISRL 372
EL +R+ + +S +K L L T L + K L + RL
Sbjct: 366 ELKSRLCTLQKKYDTSQDEQNELLKMQLQLQTELRQLKVM---KSTLVENQSEKELLCRL 422
Query: 373 EKTRSKSEDSALFTHHSLGSEVNKII---------IQSSNKQILINKNISESLGEQNRTE 423
+K H ++ E K++ +Q ++ ++ S E N
Sbjct: 423 QKLH--------LQHQNVTCEKEKLLERQQQLQEELQCHEAELQHLRDTVASFKESNE-- 472
Query: 424 YGKDSNTDKHLEPLKSL----GGRTSKRKKTEEESEHEVSCPQASFDKENA-FPFPMDNQ 478
KD+ T L+ +K L ++K ++ E ++ Q + A P P D
Sbjct: 473 --KDTETHAQLQEMKQLYQASKDELERQKHMYDQLEQDLLLCQLELKELKASHPIPEDKG 530
Query: 479 FSMNG-DCVMDKPLDLSDRFSAIQRQ 503
N D ++ + +L +++ A Q++
Sbjct: 531 KCANKCDTLLSRLTELQEKYKASQKE 556
Score = 33.9 bits (76), Expect = 0.67
Identities = 29/141 (20%), Positives = 62/141 (43%), Gaps = 33/141 (23%)
Query: 29 ECHDREVQGLQVKVTKLKQERILDA------QRLEEFFTKNQQLREQQKVLHETIK---- 78
+CH+ E+Q L+ V K+ D Q +++ + ++ E+QK +++ ++
Sbjct: 451 QCHEAELQHLRDTVASFKESNEKDTETHAQLQEMKQLYQASKDELERQKHMYDQLEQDLL 510
Query: 79 --------------VLEDRLR-AGLCD----RCAVTEEHMRKKQQEFENIRQQNLKLITE 119
+ ED+ + A CD R +E + Q+E ++ + E
Sbjct: 511 LCQLELKELKASHPIPEDKGKCANKCDTLLSRLTELQEKYKASQKEMGQLQMEQC----E 566
Query: 120 LMNERNTLQEENKKLSEQLQQ 140
L+ ++ +QEE +L E+L +
Sbjct: 567 LLEDQRRMQEEQGQLQEELHR 587
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 53.1 bits (126), Expect = 1e-06
Identities = 100/561 (17%), Positives = 217/561 (38%), Gaps = 82/561 (14%)
Query: 32 DREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQQKVLHETIKVLEDRLRAGLCDR 91
+ E+Q ++ K+K+++ LEE K+QQL E++ +L E ++ L
Sbjct: 851 EEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQA-----ETELFAE 905
Query: 92 CAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQQKIENDQQHQAA 151
+ K+QE E I + E LQ E KK+ +Q E + + A
Sbjct: 906 AEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGA 965
Query: 152 ELECE-EDVIPDSPITAFSFSGVNRLRRKENPHVRYIEQTHTKLEH-SVCANEMRKVSKS 209
+ + E V ++ I + E+ + ++I++ + + C++++ + +
Sbjct: 966 RQKLQLEKVTAEAKIKKME----EEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEK 1021
Query: 210 STHPQHNPNENEILVAD----------TYDQSQSPMAKAHGTSSYTPDKSSFNLATVVAE 259
+ + N+ E++++D T + + K G ++ D+ + A +
Sbjct: 1022 AKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDEL 1081
Query: 260 TLGLGVQEESETQGPMSPLGDELYH---CLEGNHKKQ----------PFEESTRNTEDSL 306
L L +EE E QG ++ DE H L+ + Q E+++RN +
Sbjct: 1082 KLQLAKKEE-ELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQ 1140
Query: 307 R-------------FSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDLNTSLSPSLLQP 353
+ D+ T Q+EL T+ V + +K L+ T + +Q
Sbjct: 1141 KRDLSEELEALKTELEDTLDTTAAQQELRTKREQEV----AELKKALEEETKNHEAQIQD 1196
Query: 354 GKKKHLKTLPFSNTCISRLEKTRSKSEDSALFTHHSLGSEVNKIIIQSSNKQILINKNIS 413
+++H + LE+ + E + F E NK +++ NK++ +
Sbjct: 1197 MRQRH----------ATALEELSEQLEQAKRF---KANLEKNKQGLETDNKELACEVKVL 1243
Query: 414 ESLGEQNRTEYGKDSNTDKHLEPLKSLGGR-----TSKRKKTEEESEH------EVSCPQ 462
+ + ++ + K + L S G R K K + E ++ E
Sbjct: 1244 QQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKG 1303
Query: 463 ASFDKENAFPFPMDNQFSMNGDCVMD---KPLDLSDRFSAIQRQEKSQGSETSKNKFRQV 519
F K+ A +++Q + + + + L+LS R ++ ++ S + + + +
Sbjct: 1304 IKFAKDAA---SLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARK 1360
Query: 520 TLYEALKTIPKGFSSSRKASD 540
L + + + + ++K D
Sbjct: 1361 NLEKQVLALQSQLADTKKKVD 1381
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 52.8 bits (125), Expect = 1e-06
Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 19/140 (13%)
Query: 27 LKECHDREVQGLQVKVTKLKQERILDAQR--LEEFF----TKNQQLREQQKVLHETIKVL 80
L+E + L K + L++ER ++ ++ LE+ F K QQLRE+Q+ + ++
Sbjct: 2485 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2544
Query: 81 EDRLRAGLCD---RCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQ 137
RL A + + R EE +R+KQ+E + + QQ + L EEN++L EQ
Sbjct: 2545 RQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR-------RQQEELLAEENQRLREQ 2597
Query: 138 LQQKIENDQQHQAAELECEE 157
LQ ++QH+AA EE
Sbjct: 2598 LQLL---EEQHRAALAHSEE 2614
Score = 39.7 bits (91), Expect = 0.012
Identities = 35/136 (25%), Positives = 70/136 (51%), Gaps = 8/136 (5%)
Query: 28 KECHDREVQGLQVKVTKLK---QERIL-DAQRLEE-FFTKNQQLREQQKVLHETIKVLED 82
KE +E + LQ+K +++ QE++L + Q L++ F ++ L ++++ + + LE
Sbjct: 2459 KEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQ 2518
Query: 83 RLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQQKI 142
+ + + EE R+ QQ+ E RQ+ + + E ++ +E ++ E+LQQ
Sbjct: 2519 LFQDEVAKAQQLREEQQRQ-QQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQL- 2576
Query: 143 ENDQQHQAAELECEED 158
Q+ Q EL EE+
Sbjct: 2577 -EQQRRQQEELLAEEN 2591
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 52.8 bits (125), Expect = 1e-06
Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 19/140 (13%)
Query: 27 LKECHDREVQGLQVKVTKLKQERILDAQR--LEEFF----TKNQQLREQQKVLHETIKVL 80
L+E + L K + L++ER ++ ++ LE+ F K QQLRE+Q+ + ++
Sbjct: 2489 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2548
Query: 81 EDRLRAGLCD---RCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQ 137
RL A + + R EE +R+KQ+E + + QQ + L EEN++L EQ
Sbjct: 2549 RQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR-------RQQEELLAEENQRLREQ 2601
Query: 138 LQQKIENDQQHQAAELECEE 157
LQ ++QH+AA EE
Sbjct: 2602 LQLL---EEQHRAALAHSEE 2618
Score = 39.7 bits (91), Expect = 0.012
Identities = 35/136 (25%), Positives = 70/136 (51%), Gaps = 8/136 (5%)
Query: 28 KECHDREVQGLQVKVTKLK---QERIL-DAQRLEE-FFTKNQQLREQQKVLHETIKVLED 82
KE +E + LQ+K +++ QE++L + Q L++ F ++ L ++++ + + LE
Sbjct: 2463 KEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQ 2522
Query: 83 RLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQQKI 142
+ + + EE R+ QQ+ E RQ+ + + E ++ +E ++ E+LQQ
Sbjct: 2523 LFQDEVAKAQQLREEQQRQ-QQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQL- 2580
Query: 143 ENDQQHQAAELECEED 158
Q+ Q EL EE+
Sbjct: 2581 -EQQRRQQEELLAEEN 2595
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 52.8 bits (125), Expect = 1e-06
Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 19/140 (13%)
Query: 27 LKECHDREVQGLQVKVTKLKQERILDAQR--LEEFF----TKNQQLREQQKVLHETIKVL 80
L+E + L K + L++ER ++ ++ LE+ F K QQLRE+Q+ + ++
Sbjct: 2485 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2544
Query: 81 EDRLRAGLCD---RCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQ 137
RL A + + R EE +R+KQ+E + + QQ + L EEN++L EQ
Sbjct: 2545 RQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR-------RQQEELLAEENQRLREQ 2597
Query: 138 LQQKIENDQQHQAAELECEE 157
LQ ++QH+AA EE
Sbjct: 2598 LQLL---EEQHRAALAHSEE 2614
Score = 39.7 bits (91), Expect = 0.012
Identities = 35/136 (25%), Positives = 70/136 (51%), Gaps = 8/136 (5%)
Query: 28 KECHDREVQGLQVKVTKLK---QERIL-DAQRLEE-FFTKNQQLREQQKVLHETIKVLED 82
KE +E + LQ+K +++ QE++L + Q L++ F ++ L ++++ + + LE
Sbjct: 2459 KEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQ 2518
Query: 83 RLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQQKI 142
+ + + EE R+ QQ+ E RQ+ + + E ++ +E ++ E+LQQ
Sbjct: 2519 LFQDEVAKAQQLREEQQRQ-QQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQL- 2576
Query: 143 ENDQQHQAAELECEED 158
Q+ Q EL EE+
Sbjct: 2577 -EQQRRQQEELLAEEN 2591
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 52.8 bits (125), Expect = 1e-06
Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 19/140 (13%)
Query: 27 LKECHDREVQGLQVKVTKLKQERILDAQR--LEEFF----TKNQQLREQQKVLHETIKVL 80
L+E + L K + L++ER ++ ++ LE+ F K QQLRE+Q+ + ++
Sbjct: 2453 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2512
Query: 81 EDRLRAGLCD---RCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQ 137
RL A + + R EE +R+KQ+E + + QQ + L EEN++L EQ
Sbjct: 2513 RQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR-------RQQEELLAEENQRLREQ 2565
Query: 138 LQQKIENDQQHQAAELECEE 157
LQ ++QH+AA EE
Sbjct: 2566 LQLL---EEQHRAALAHSEE 2582
Score = 39.7 bits (91), Expect = 0.012
Identities = 35/136 (25%), Positives = 70/136 (51%), Gaps = 8/136 (5%)
Query: 28 KECHDREVQGLQVKVTKLK---QERIL-DAQRLEE-FFTKNQQLREQQKVLHETIKVLED 82
KE +E + LQ+K +++ QE++L + Q L++ F ++ L ++++ + + LE
Sbjct: 2427 KEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQ 2486
Query: 83 RLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQQKI 142
+ + + EE R+ QQ+ E RQ+ + + E ++ +E ++ E+LQQ
Sbjct: 2487 LFQDEVAKAQQLREEQQRQ-QQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQL- 2544
Query: 143 ENDQQHQAAELECEED 158
Q+ Q EL EE+
Sbjct: 2545 -EQQRRQQEELLAEEN 2559
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 52.8 bits (125), Expect = 1e-06
Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 19/140 (13%)
Query: 27 LKECHDREVQGLQVKVTKLKQERILDAQR--LEEFF----TKNQQLREQQKVLHETIKVL 80
L+E + L K + L++ER ++ ++ LE+ F K QQLRE+Q+ + ++
Sbjct: 2622 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2681
Query: 81 EDRLRAGLCD---RCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQ 137
RL A + + R EE +R+KQ+E + + QQ + L EEN++L EQ
Sbjct: 2682 RQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR-------RQQEELLAEENQRLREQ 2734
Query: 138 LQQKIENDQQHQAAELECEE 157
LQ ++QH+AA EE
Sbjct: 2735 LQLL---EEQHRAALAHSEE 2751
Score = 39.7 bits (91), Expect = 0.012
Identities = 35/136 (25%), Positives = 70/136 (51%), Gaps = 8/136 (5%)
Query: 28 KECHDREVQGLQVKVTKLK---QERIL-DAQRLEE-FFTKNQQLREQQKVLHETIKVLED 82
KE +E + LQ+K +++ QE++L + Q L++ F ++ L ++++ + + LE
Sbjct: 2596 KEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQ 2655
Query: 83 RLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQQKI 142
+ + + EE R+ QQ+ E RQ+ + + E ++ +E ++ E+LQQ
Sbjct: 2656 LFQDEVAKAQQLREEQQRQ-QQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQL- 2713
Query: 143 ENDQQHQAAELECEED 158
Q+ Q EL EE+
Sbjct: 2714 -EQQRRQQEELLAEEN 2728
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 52.8 bits (125), Expect = 1e-06
Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 19/140 (13%)
Query: 27 LKECHDREVQGLQVKVTKLKQERILDAQR--LEEFF----TKNQQLREQQKVLHETIKVL 80
L+E + L K + L++ER ++ ++ LE+ F K QQLRE+Q+ + ++
Sbjct: 2463 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2522
Query: 81 EDRLRAGLCD---RCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQ 137
RL A + + R EE +R+KQ+E + + QQ + L EEN++L EQ
Sbjct: 2523 RQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR-------RQQEELLAEENQRLREQ 2575
Query: 138 LQQKIENDQQHQAAELECEE 157
LQ ++QH+AA EE
Sbjct: 2576 LQLL---EEQHRAALAHSEE 2592
Score = 39.7 bits (91), Expect = 0.012
Identities = 35/136 (25%), Positives = 70/136 (51%), Gaps = 8/136 (5%)
Query: 28 KECHDREVQGLQVKVTKLK---QERIL-DAQRLEE-FFTKNQQLREQQKVLHETIKVLED 82
KE +E + LQ+K +++ QE++L + Q L++ F ++ L ++++ + + LE
Sbjct: 2437 KEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQ 2496
Query: 83 RLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQQKI 142
+ + + EE R+ QQ+ E RQ+ + + E ++ +E ++ E+LQQ
Sbjct: 2497 LFQDEVAKAQQLREEQQRQ-QQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQL- 2554
Query: 143 ENDQQHQAAELECEED 158
Q+ Q EL EE+
Sbjct: 2555 -EQQRRQQEELLAEEN 2569
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 52.8 bits (125), Expect = 1e-06
Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 19/140 (13%)
Query: 27 LKECHDREVQGLQVKVTKLKQERILDAQR--LEEFF----TKNQQLREQQKVLHETIKVL 80
L+E + L K + L++ER ++ ++ LE+ F K QQLRE+Q+ + ++
Sbjct: 2471 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2530
Query: 81 EDRLRAGLCD---RCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQ 137
RL A + + R EE +R+KQ+E + + QQ + L EEN++L EQ
Sbjct: 2531 RQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR-------RQQEELLAEENQRLREQ 2583
Query: 138 LQQKIENDQQHQAAELECEE 157
LQ ++QH+AA EE
Sbjct: 2584 LQLL---EEQHRAALAHSEE 2600
Score = 39.7 bits (91), Expect = 0.012
Identities = 35/136 (25%), Positives = 70/136 (51%), Gaps = 8/136 (5%)
Query: 28 KECHDREVQGLQVKVTKLK---QERIL-DAQRLEE-FFTKNQQLREQQKVLHETIKVLED 82
KE +E + LQ+K +++ QE++L + Q L++ F ++ L ++++ + + LE
Sbjct: 2445 KEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQ 2504
Query: 83 RLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQQKI 142
+ + + EE R+ QQ+ E RQ+ + + E ++ +E ++ E+LQQ
Sbjct: 2505 LFQDEVAKAQQLREEQQRQ-QQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQL- 2562
Query: 143 ENDQQHQAAELECEED 158
Q+ Q EL EE+
Sbjct: 2563 -EQQRRQQEELLAEEN 2577
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 52.8 bits (125), Expect = 1e-06
Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 19/140 (13%)
Query: 27 LKECHDREVQGLQVKVTKLKQERILDAQR--LEEFF----TKNQQLREQQKVLHETIKVL 80
L+E + L K + L++ER ++ ++ LE+ F K QQLRE+Q+ + ++
Sbjct: 2512 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2571
Query: 81 EDRLRAGLCD---RCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQ 137
RL A + + R EE +R+KQ+E + + QQ + L EEN++L EQ
Sbjct: 2572 RQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR-------RQQEELLAEENQRLREQ 2624
Query: 138 LQQKIENDQQHQAAELECEE 157
LQ ++QH+AA EE
Sbjct: 2625 LQLL---EEQHRAALAHSEE 2641
Score = 39.7 bits (91), Expect = 0.012
Identities = 35/136 (25%), Positives = 70/136 (51%), Gaps = 8/136 (5%)
Query: 28 KECHDREVQGLQVKVTKLK---QERIL-DAQRLEE-FFTKNQQLREQQKVLHETIKVLED 82
KE +E + LQ+K +++ QE++L + Q L++ F ++ L ++++ + + LE
Sbjct: 2486 KEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQ 2545
Query: 83 RLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQQKI 142
+ + + EE R+ QQ+ E RQ+ + + E ++ +E ++ E+LQQ
Sbjct: 2546 LFQDEVAKAQQLREEQQRQ-QQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQL- 2603
Query: 143 ENDQQHQAAELECEED 158
Q+ Q EL EE+
Sbjct: 2604 -EQQRRQQEELLAEEN 2618
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 52.4 bits (124), Expect = 2e-06
Identities = 166/826 (20%), Positives = 322/826 (38%), Gaps = 109/826 (13%)
Query: 28 KECHDREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLRE------------------- 68
K +R++Q + +L+QE + + RL+E + QQ++E
Sbjct: 1931 KTLFERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPV 1990
Query: 69 QQKVLHETIKVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNT-- 126
+Q++L ET K+++++L C V ++ ++K+ + E ++ + EL E+NT
Sbjct: 1991 EQQLLQETEKLMKEKLEV-QCQAEKVRDD-LQKQVKALEIDVEEQVSRFIELEQEKNTEL 2048
Query: 127 --LQEENKKLSEQLQQKIENDQQHQAAELECEEDVI-PDSPITAFSFSGVNRLRRKENPH 183
L+++N+ L +QL +K+ QA + E E DV + V R +
Sbjct: 2049 MDLRQQNQALEKQL-EKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPRFQPISEHQ 2107
Query: 184 VRYIEQ--THTKLEHSVCANEMRKVSKSSTHPQHNPNENEILVADTYDQSQSPMAKAHGT 241
R +EQ H K + C+ + + Q E E L + Q+ + A T
Sbjct: 2108 TREVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSA-DT 2166
Query: 242 SSYTPDKSSFNLATVVAETLGLGVQEESE------TQGPMSPLGDELYHCLEGNHKKQPF 295
D+ F E L L VQ ++E + ++ L ++L E K
Sbjct: 2167 FQKVEDRKHFGAVEAKPE-LSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNE- 2224
Query: 296 EESTRNTEDSLRFSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDLNTSLSPSLLQPGK 355
E + + ++ +ST++ E+ + +IK ++T L
Sbjct: 2225 EVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQHVLF---- 2280
Query: 356 KKHLKTLPFSNTCISRLEKTRSKSEDSALFTHHSLGSEVNKIIIQSSNKQILINKNISES 415
K + + I +L + +K + T + E +I+ QI + E
Sbjct: 2281 GKFAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQEC 2340
Query: 416 LGEQNRTEYGKDSN--TDKHLEPLKSLGGRTSKRKKTEEESEHEVSCPQASFDKENAFPF 473
+ ++NR E + N +K + L ++G +TS + E E + D A
Sbjct: 2341 V-KRNREEEIEQLNEVIEKLQQELANIGQKTSMNAHSLSE---EADSLKHQLDVVIAEKL 2396
Query: 474 PMDNQF-SMNGDCVMDKPLDLSDRFSAIQRQEKSQGSETSKNKFRQVTLYEALKTIPKGF 532
++ Q + N + K + F + +Q ++ + R+ E +++IP+
Sbjct: 2397 ALEQQVETANEEMTFMKNVLKETNF------KMNQLTQELFSLKRERESVEKIQSIPE-- 2448
Query: 533 SSSRKASDGNCTLPKDSPGEPCSQECIILQPLNKCSPDNKPSLQIKEENAVFKIPLRPRE 592
+S A D L KD P E ++ + K S +N+ + EEN I
Sbjct: 2449 NSVNVAID---HLSKDKP----ELEVVLTEDALK-SLENQTYFKSFEENGKGSIINLETR 2500
Query: 593 SLETENV--------------LDDIKSAGSHEPIKIQTR--------SDHGGCELASVLQ 630
L+ E+ + D++ G E +Q + + L S +Q
Sbjct: 2501 LLQLESTVSAKDLELTQCYKQIKDMQEQGQFETEMLQKKIVNLQKIVEEKVAAALVSQIQ 2560
Query: 631 LNPCRTGKIKSLQNNQDVSFENIQWSIDPGADLSQYKM--DVTVIDTKDGSQSKLGGETV 688
L + K Q+NQ +S E + +I L + ++ D++ + + S+L + V
Sbjct: 2561 LEAVQE-YAKFCQDNQTISSEPERTNIQNLNQLREDELGSDISALTLR---ISELESQVV 2616
Query: 689 DMDCTLV---------------SETVLLKMKKQEQKGEKSSNEERKMNDSLEDMFDRTTH 733
+M +L+ E LL+++K + EK E+ K + +TT
Sbjct: 2617 EMHTSLILEKEQVEIAEKNVLEKEKKLLELQKLLEGNEKKQREKEKKRSPQDVEVLKTTT 2676
Query: 734 EEYESCLADSFSQAADEEEELSTATK-KLHTHGDKQDKVKQKAFVE 778
E + S F + S ATK +L ++ +K +K++++ V+
Sbjct: 2677 ELFHSNEESGFFNELEALRAESVATKAELASYKEKAEKLQEELLVK 2722
Score = 41.6 bits (96), Expect = 0.003
Identities = 45/187 (24%), Positives = 87/187 (46%), Gaps = 20/187 (10%)
Query: 26 KLKECHDREVQGLQVKVTKLKQERILDAQRLEEFFTK----NQQLREQQKVLHETIKV-- 79
K K ++EVQ LQ+K L+++ L+E F + N L++++K L + +K+
Sbjct: 736 KEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDMLKIHT 795
Query: 80 ---LEDRL----RAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENK 132
E+RL + +V E+ + +E E+++QQ ++L E+ +RNT K
Sbjct: 796 PVSQEERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTFSFAEK 855
Query: 133 KLSEQLQQKIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRR-KENPHVRYIEQTH 191
Q+ Q+ A L+ ++D+ + ++L+ E H++ I T
Sbjct: 856 NFEVNYQEL----QEEYACLLKVKDDLEDSKNKQELEYK--SKLKALNEELHLQRINPTT 909
Query: 192 TKLEHSV 198
K++ SV
Sbjct: 910 VKMKSSV 916
Score = 39.3 bits (90), Expect = 0.016
Identities = 32/115 (27%), Positives = 62/115 (53%), Gaps = 4/115 (3%)
Query: 53 AQRLEEF-FTKNQQLREQQKVLHETIKVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQ 111
+Q++E F K+ + +Q +++ E K L+D ++ + + + + Q+E E +RQ
Sbjct: 675 SQKIETMQFEKDNLITKQNQLILEISK-LKDLQQSLVNSKSEEMTLQINELQKEIEILRQ 733
Query: 112 QNLKLITELMNERNTLQEENKKLSEQLQQKIENDQQHQAAELECEEDVIPDSPIT 166
+ + T L E LQ + + L +Q+++K END Q + A+LE E ++ D T
Sbjct: 734 EEKEKGT-LEQEVQELQLKTELLEKQMKEK-ENDLQEKFAQLEAENSILKDEKKT 786
Score = 35.4 bits (80), Expect = 0.23
Identities = 29/109 (26%), Positives = 52/109 (47%), Gaps = 16/109 (14%)
Query: 57 EEFFTKNQQLREQQKVLHETIKVL-----------EDRLRAGLCDRCAVTEEHMRKKQQE 105
EE F+K++ +Q + H+ I V E++L + +EH QQ
Sbjct: 1550 EEMFSKDKTFIVRQSI-HDEISVSSMDASRQLMLNEEQLEDMRQELVRQYQEH----QQA 1604
Query: 106 FENIRQQNLKLITELMNERNTLQEENKKLSEQLQQKIENDQQHQAAELE 154
E +RQ +++ + ++ LQEE K+L+ QL Q+ D ++ +E E
Sbjct: 1605 TELLRQAHMRQMERQREDQEQLQEEIKRLNRQLAQRSSIDNENLVSERE 1653
Score = 31.2 bits (69), Expect = 4.3
Identities = 41/218 (18%), Positives = 91/218 (41%), Gaps = 48/218 (22%)
Query: 32 DREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQ------------QKVLHETIKV 79
++E++ +++++T KQ+ ++ +++ ++L+++ Q++ ET +
Sbjct: 370 NQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRK 429
Query: 80 LEDRLRAGLCD----------------RCAVTEEHMRKKQQEFEN---------IRQQNL 114
LE +LRA L + A EE + + E EN + + +
Sbjct: 430 LE-QLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYSNITVNEDQI 488
Query: 115 KLITELMNERNTLQEENKKLSEQLQQKIENDQQHQAAELECEEDVIPDSPITAFSFSGVN 174
KL+ +NE N ++ E+L++++ + + A ED++ + +FS +
Sbjct: 489 KLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEE---LSFSREQIQ 545
Query: 175 RLRRKENPHVRYIEQTHTKLE-------HSVCANEMRK 205
R R+ + + H L V A+E RK
Sbjct: 546 RARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRK 583
Score = 31.2 bits (69), Expect = 4.3
Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 14/74 (18%)
Query: 96 EEHMRKKQQEFENIRQQNLKLITELMNERNTLQE----ENKKLSEQ----------LQQK 141
EE++ K++ EF +I Q L +N ++ L E KL EQ LQQ+
Sbjct: 1294 EENLPKEETEFLSIHSQMTNLEDIDVNHKSKLSSLQDLEKTKLEEQVQELESLISSLQQQ 1353
Query: 142 IENDQQHQAAELEC 155
++ +Q+ AE+ C
Sbjct: 1354 LKETEQNYEAEIHC 1367
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 48.5 bits (114), Expect = 3e-05
Identities = 164/826 (19%), Positives = 321/826 (38%), Gaps = 117/826 (14%)
Query: 28 KECHDREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLRE------------------- 68
K +R++Q + +L+QE + + RL+E + QQ++E
Sbjct: 1931 KTLFERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPV 1990
Query: 69 QQKVLHETIKVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNT-- 126
+Q++L ET K+++++L C V ++ ++K+ + E ++ + EL E+NT
Sbjct: 1991 EQQLLQETEKLMKEKLEV-QCQAEKVRDD-LQKQVKALEIDVEEQVSRFIELEQEKNTEL 2048
Query: 127 --LQEENKKLSEQLQQKIENDQQHQAAELECEEDVI-PDSPITAFSFSGVNRLRRKENPH 183
L+++N+ L +QL +K+ QA + E E DV + V R +
Sbjct: 2049 MDLRQQNQALEKQL-EKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPRFQPISEHQ 2107
Query: 184 VRYIEQ--THTKLEHSVCANEMRKVSKSSTHPQHNPNENEILVADTYDQSQSPMAKAHGT 241
R +EQ H K + C+ + + Q E E L + Q+ + +
Sbjct: 2108 TREVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVE---- 2163
Query: 242 SSYTPDKSSFNLATVVAETLGLGVQEESE------TQGPMSPLGDELYHCLEGNHKKQPF 295
D+ F E L L VQ ++E + ++ L ++L E K
Sbjct: 2164 -----DRKHFGAVEAKPE-LSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNE- 2216
Query: 296 EESTRNTEDSLRFSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDLNTSLSPSLLQPGK 355
E + + ++ +ST++ E+ + +IK ++T L
Sbjct: 2217 EVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQHVLF---- 2272
Query: 356 KKHLKTLPFSNTCISRLEKTRSKSEDSALFTHHSLGSEVNKIIIQSSNKQILINKNISES 415
K + + I +L + +K + T + E +I+ QI + E
Sbjct: 2273 GKFAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQEC 2332
Query: 416 LGEQNRTEYGKDSN--TDKHLEPLKSLGGRTSKRKKTEEESEHEVSCPQASFDKENAFPF 473
+ ++NR E + N +K + L ++G +TS + E E + D A
Sbjct: 2333 V-KRNREEEIEQLNEVIEKLQQELANIGQKTSMNAHSLSE---EADSLKHQLDVVIAEKL 2388
Query: 474 PMDNQF-SMNGDCVMDKPLDLSDRFSAIQRQEKSQGSETSKNKFRQVTLYEALKTIPKGF 532
++ Q + N + K + F + +Q ++ + R+ E +++IP+
Sbjct: 2389 ALEQQVETANEEMTFMKNVLKETNF------KMNQLTQELFSLKRERESVEKIQSIPE-- 2440
Query: 533 SSSRKASDGNCTLPKDSPGEPCSQECIILQPLNKCSPDNKPSLQIKEENAVFKIPLRPRE 592
+S A D L KD P E ++ + K S +N+ + EEN I
Sbjct: 2441 NSVNVAID---HLSKDKP----ELEVVLTEDALK-SLENQTYFKSFEENGKGSIINLETR 2492
Query: 593 SLETENV--------------LDDIKSAGSHEPIKIQTR--------SDHGGCELASVLQ 630
L+ E+ + D++ G E +Q + + L S +Q
Sbjct: 2493 LLQLESTVSAKDLELTQCYKQIKDMQEQGQFETEMLQKKIVNLQKIVEEKVAAALVSQIQ 2552
Query: 631 LNPCRTGKIKSLQNNQDVSFENIQWSIDPGADLSQYKM--DVTVIDTKDGSQSKLGGETV 688
L + K Q+NQ +S E + +I L + ++ D++ + + S+L + V
Sbjct: 2553 LEAVQE-YAKFCQDNQTISSEPERTNIQNLNQLREDELGSDISALTLR---ISELESQVV 2608
Query: 689 DMDCTLV---------------SETVLLKMKKQEQKGEKSSNEERKMNDSLEDMFDRTTH 733
+M +L+ E LL+++K + EK E+ K + +TT
Sbjct: 2609 EMHTSLILEKEQVEIAEKNVLEKEKKLLELQKLLEGNEKKQREKEKKRSPQDVEVLKTTT 2668
Query: 734 EEYESCLADSFSQAADEEEELSTATK-KLHTHGDKQDKVKQKAFVE 778
E + S F + S ATK +L ++ +K +K++++ V+
Sbjct: 2669 ELFHSNEESGFFNELEALRAESVATKAELASYKEKAEKLQEELLVK 2714
Score = 41.6 bits (96), Expect = 0.003
Identities = 45/187 (24%), Positives = 87/187 (46%), Gaps = 20/187 (10%)
Query: 26 KLKECHDREVQGLQVKVTKLKQERILDAQRLEEFFTK----NQQLREQQKVLHETIKV-- 79
K K ++EVQ LQ+K L+++ L+E F + N L++++K L + +K+
Sbjct: 736 KEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDMLKIHT 795
Query: 80 ---LEDRL----RAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENK 132
E+RL + +V E+ + +E E+++QQ ++L E+ +RNT K
Sbjct: 796 PVSQEERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTFSFAEK 855
Query: 133 KLSEQLQQKIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRR-KENPHVRYIEQTH 191
Q+ Q+ A L+ ++D+ + ++L+ E H++ I T
Sbjct: 856 NFEVNYQEL----QEEYACLLKVKDDLEDSKNKQELEYK--SKLKALNEELHLQRINPTT 909
Query: 192 TKLEHSV 198
K++ SV
Sbjct: 910 VKMKSSV 916
Score = 39.3 bits (90), Expect = 0.016
Identities = 32/115 (27%), Positives = 62/115 (53%), Gaps = 4/115 (3%)
Query: 53 AQRLEEF-FTKNQQLREQQKVLHETIKVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQ 111
+Q++E F K+ + +Q +++ E K L+D ++ + + + + Q+E E +RQ
Sbjct: 675 SQKIETMQFEKDNLITKQNQLILEISK-LKDLQQSLVNSKSEEMTLQINELQKEIEILRQ 733
Query: 112 QNLKLITELMNERNTLQEENKKLSEQLQQKIENDQQHQAAELECEEDVIPDSPIT 166
+ + T L E LQ + + L +Q+++K END Q + A+LE E ++ D T
Sbjct: 734 EEKEKGT-LEQEVQELQLKTELLEKQMKEK-ENDLQEKFAQLEAENSILKDEKKT 786
Score = 35.4 bits (80), Expect = 0.23
Identities = 29/109 (26%), Positives = 52/109 (47%), Gaps = 16/109 (14%)
Query: 57 EEFFTKNQQLREQQKVLHETIKVL-----------EDRLRAGLCDRCAVTEEHMRKKQQE 105
EE F+K++ +Q + H+ I V E++L + +EH QQ
Sbjct: 1550 EEMFSKDKTFIVRQSI-HDEISVSSMDASRQLMLNEEQLEDMRQELVRQYQEH----QQA 1604
Query: 106 FENIRQQNLKLITELMNERNTLQEENKKLSEQLQQKIENDQQHQAAELE 154
E +RQ +++ + ++ LQEE K+L+ QL Q+ D ++ +E E
Sbjct: 1605 TELLRQAHMRQMERQREDQEQLQEEIKRLNRQLAQRSSIDNENLVSERE 1653
Score = 31.6 bits (70), Expect = 3.3
Identities = 29/133 (21%), Positives = 65/133 (48%), Gaps = 9/133 (6%)
Query: 15 DTSSDFKDLWTKLKECHDREVQGLQVKVTKL----KQERILDAQ--RLEEFFTKNQQLRE 68
D K L ++E R ++ Q K T+L +Q + L+ Q ++ +F + RE
Sbjct: 2018 DLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDRE 2077
Query: 69 QQK-VLHETIKVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTL 127
++ V + I+ LE +L+ + R EH ++ ++ N ++ +EL+ + L
Sbjct: 2078 HERDVFQQEIQKLEQQLK--VVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQL 2135
Query: 128 QEENKKLSEQLQQ 140
Q + ++ +E++++
Sbjct: 2136 QRDIQERNEEIEK 2148
Score = 31.2 bits (69), Expect = 4.3
Identities = 41/218 (18%), Positives = 91/218 (41%), Gaps = 48/218 (22%)
Query: 32 DREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQ------------QKVLHETIKV 79
++E++ +++++T KQ+ ++ +++ ++L+++ Q++ ET +
Sbjct: 370 NQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRK 429
Query: 80 LEDRLRAGLCD----------------RCAVTEEHMRKKQQEFEN---------IRQQNL 114
LE +LRA L + A EE + + E EN + + +
Sbjct: 430 LE-QLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYSNITVNEDQI 488
Query: 115 KLITELMNERNTLQEENKKLSEQLQQKIENDQQHQAAELECEEDVIPDSPITAFSFSGVN 174
KL+ +NE N ++ E+L++++ + + A ED++ + +FS +
Sbjct: 489 KLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEE---LSFSREQIQ 545
Query: 175 RLRRKENPHVRYIEQTHTKLE-------HSVCANEMRK 205
R R+ + + H L V A+E RK
Sbjct: 546 RARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRK 583
Score = 31.2 bits (69), Expect = 4.3
Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 14/74 (18%)
Query: 96 EEHMRKKQQEFENIRQQNLKLITELMNERNTLQE----ENKKLSEQ----------LQQK 141
EE++ K++ EF +I Q L +N ++ L E KL EQ LQQ+
Sbjct: 1294 EENLPKEETEFLSIHSQMTNLEDIDVNHKSKLSSLQDLEKTKLEEQVQELESLISSLQQQ 1353
Query: 142 IENDQQHQAAELEC 155
++ +Q+ AE+ C
Sbjct: 1354 LKETEQNYEAEIHC 1367
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 46.2 bits (108), Expect = 1e-04
Identities = 54/203 (26%), Positives = 91/203 (44%), Gaps = 11/203 (5%)
Query: 40 VKVTKLKQERILDAQRLE--EFF-TKNQQLREQQKVLHETIKVLEDRLRA--GLCDRCAV 94
V+V KL+ E +RL EF+ + ++L+E +VL ET +LED+L D+
Sbjct: 320 VRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHE 379
Query: 95 TEE---HMRKKQQEFENIRQQNLKLITELMNERNTLQEENKK-LSEQLQQKIENDQQHQA 150
E+ ++ K + E R + K I ELM E TL+ K+ + E L E +Q +
Sbjct: 380 LEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRT 439
Query: 151 AELECEEDVIPDSPITAFSFSGVNRLRRKENPHVRYIEQTHTKLEHSVCANEMRKVSKSS 210
+EL + + S + +L + + +E+ T ++ SV N K+ K
Sbjct: 440 SELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVD-SVEGN-ASKILKME 497
Query: 211 THPQHNPNENEILVADTYDQSQS 233
Q + EIL + + QS
Sbjct: 498 KENQRLSKKVEILENEIVQEKQS 520
Score = 38.9 bits (89), Expect = 0.021
Identities = 38/127 (29%), Positives = 63/127 (49%), Gaps = 9/127 (7%)
Query: 41 KVTKLKQERILDAQ-RLEEFFTKNQQLREQQKVL---HETIKVLEDRLRAGLCDRCAVTE 96
K ++K+E+I + RLEE NQQLR++ K + +E +K +D R E
Sbjct: 967 KSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGE 1026
Query: 97 EHMRKKQQEFENIRQQNLKLITELMN-ERN--TLQEENKKLSEQLQQKIENDQQHQAAEL 153
++ K ++E + ++ LK+ L+ ERN TLQ E + L QL+Q + QA L
Sbjct: 1027 DN--KWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQIL 1084
Query: 154 ECEEDVI 160
+ +
Sbjct: 1085 ALQRQTV 1091
Score = 34.3 bits (77), Expect = 0.51
Identities = 45/230 (19%), Positives = 101/230 (43%), Gaps = 25/230 (10%)
Query: 31 HDREVQGLQVKVT--KLKQERILDAQRLEEFFTKNQQLREQQKV-LHETIKV---LEDRL 84
H+ E + LQ+K ++ ER +D +++EE +N L QK + E++ + LE
Sbjct: 378 HELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQIS 437
Query: 85 RAGLCDRCA----------VTEEHMRKKQQEFENIRQQNLKLITELMNERNT------LQ 128
R +T + K + E +++ + +L T + + ++
Sbjct: 438 RTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKME 497
Query: 129 EENKKLSEQLQQKIENDQQHQAAELECEEDVIPD-SPITAFSFSGVNRLRRKENPHVRYI 187
+EN++LS++++ +EN+ + L+ +++ D A + LR ++ +
Sbjct: 498 KENQRLSKKVEI-LENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKIL 556
Query: 188 EQTHTKLEHSVCANEMRKVSKSSTHPQHNPNENEILVADTYDQSQSPMAK 237
EQ + L +V + R + + EN+IL ++ ++ S ++K
Sbjct: 557 EQENEHLNQTVSSLRQRSQISAEARVKDIEKENKIL-HESIKETSSKLSK 605
Score = 33.9 bits (76), Expect = 0.67
Identities = 44/225 (19%), Positives = 98/225 (43%), Gaps = 14/225 (6%)
Query: 2 NISGSSCGSPNSADTSSDFKDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFFT 61
N+ C S A + K+L ++ ++ +GL++ K+ L+ +
Sbjct: 709 NVESLKCASMKMAQLQLENKELESEKEQLK----KGLELLKASFKKTERLEVS-YQGLDI 763
Query: 62 KNQQLREQQKVLHETIKVLEDRLRAGLCDRCAVTE--EHMRKKQQEFENIRQQNLKL--- 116
+NQ+L++ + ++ I+ LE L+ + + + E ++ + E + ++N L
Sbjct: 764 ENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQE 823
Query: 117 ITELMNERNTLQEENKKLSEQLQQKIENDQQH--QAAELECEEDVIPDSPITAFSFSGVN 174
++L ++ L++ENK+L +Q + K +++ + LE E + I + S V
Sbjct: 824 TSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTL-SKEIGIYKESCV- 881
Query: 175 RLRRKENPHVRYIEQTHTKLEHSVCANEMRKVSKSSTHPQHNPNE 219
RL+ E + +++ ++ V E K T +N E
Sbjct: 882 RLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLE 926
Score = 32.7 bits (73), Expect = 1.5
Identities = 28/147 (19%), Positives = 68/147 (46%), Gaps = 3/147 (2%)
Query: 20 FKDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQQKVLHETIKV 79
+K+ +LKE + ++ +K L + E Q + +K+ HE K+
Sbjct: 876 YKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKI 935
Query: 80 LEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQ 139
++ R L D + + + + + E+ +++L++ E + EE+ ++QL+
Sbjct: 936 GLNKERL-LHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLR 994
Query: 140 QKIENDQQHQAA--ELECEEDVIPDSP 164
Q+++ +++ A + + EE ++ SP
Sbjct: 995 QELKTVKKNYEALKQRQDEERMVQSSP 1021
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 46.2 bits (108), Expect = 1e-04
Identities = 54/203 (26%), Positives = 91/203 (44%), Gaps = 11/203 (5%)
Query: 40 VKVTKLKQERILDAQRLE--EFF-TKNQQLREQQKVLHETIKVLEDRLRA--GLCDRCAV 94
V+V KL+ E +RL EF+ + ++L+E +VL ET +LED+L D+
Sbjct: 320 VRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHE 379
Query: 95 TEE---HMRKKQQEFENIRQQNLKLITELMNERNTLQEENKK-LSEQLQQKIENDQQHQA 150
E+ ++ K + E R + K I ELM E TL+ K+ + E L E +Q +
Sbjct: 380 LEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRT 439
Query: 151 AELECEEDVIPDSPITAFSFSGVNRLRRKENPHVRYIEQTHTKLEHSVCANEMRKVSKSS 210
+EL + + S + +L + + +E+ T ++ SV N K+ K
Sbjct: 440 SELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVD-SVEGN-ASKILKME 497
Query: 211 THPQHNPNENEILVADTYDQSQS 233
Q + EIL + + QS
Sbjct: 498 KENQRLSKKVEILENEIVQEKQS 520
Score = 38.9 bits (89), Expect = 0.021
Identities = 38/127 (29%), Positives = 63/127 (49%), Gaps = 9/127 (7%)
Query: 41 KVTKLKQERILDAQ-RLEEFFTKNQQLREQQKVL---HETIKVLEDRLRAGLCDRCAVTE 96
K ++K+E+I + RLEE NQQLR++ K + +E +K +D R E
Sbjct: 966 KSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGE 1025
Query: 97 EHMRKKQQEFENIRQQNLKLITELMN-ERN--TLQEENKKLSEQLQQKIENDQQHQAAEL 153
++ K ++E + ++ LK+ L+ ERN TLQ E + L QL+Q + QA L
Sbjct: 1026 DN--KWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQIL 1083
Query: 154 ECEEDVI 160
+ +
Sbjct: 1084 ALQRQTV 1090
Score = 34.3 bits (77), Expect = 0.51
Identities = 45/230 (19%), Positives = 101/230 (43%), Gaps = 25/230 (10%)
Query: 31 HDREVQGLQVKVT--KLKQERILDAQRLEEFFTKNQQLREQQKV-LHETIKV---LEDRL 84
H+ E + LQ+K ++ ER +D +++EE +N L QK + E++ + LE
Sbjct: 378 HELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQIS 437
Query: 85 RAGLCDRCA----------VTEEHMRKKQQEFENIRQQNLKLITELMNERNT------LQ 128
R +T + K + E +++ + +L T + + ++
Sbjct: 438 RTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKME 497
Query: 129 EENKKLSEQLQQKIENDQQHQAAELECEEDVIPD-SPITAFSFSGVNRLRRKENPHVRYI 187
+EN++LS++++ +EN+ + L+ +++ D A + LR ++ +
Sbjct: 498 KENQRLSKKVEI-LENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKIL 556
Query: 188 EQTHTKLEHSVCANEMRKVSKSSTHPQHNPNENEILVADTYDQSQSPMAK 237
EQ + L +V + R + + EN+IL ++ ++ S ++K
Sbjct: 557 EQENEHLNQTVSSLRQRSQISAEARVKDIEKENKIL-HESIKETSSKLSK 605
Score = 33.9 bits (76), Expect = 0.67
Identities = 44/225 (19%), Positives = 98/225 (43%), Gaps = 14/225 (6%)
Query: 2 NISGSSCGSPNSADTSSDFKDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFFT 61
N+ C S A + K+L ++ ++ +GL++ K+ L+ +
Sbjct: 709 NVESLKCASMKMAQLQLENKELESEKEQLK----KGLELLKASFKKTERLEVS-YQGLDI 763
Query: 62 KNQQLREQQKVLHETIKVLEDRLRAGLCDRCAVTE--EHMRKKQQEFENIRQQNLKL--- 116
+NQ+L++ + ++ I+ LE L+ + + + E ++ + E + ++N L
Sbjct: 764 ENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQE 823
Query: 117 ITELMNERNTLQEENKKLSEQLQQKIENDQQH--QAAELECEEDVIPDSPITAFSFSGVN 174
++L ++ L++ENK+L +Q + K +++ + LE E + I + S V
Sbjct: 824 TSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTL-SKEIGIYKESCV- 881
Query: 175 RLRRKENPHVRYIEQTHTKLEHSVCANEMRKVSKSSTHPQHNPNE 219
RL+ E + +++ ++ V E K T +N E
Sbjct: 882 RLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLE 926
Score = 31.2 bits (69), Expect = 4.3
Identities = 29/147 (19%), Positives = 70/147 (47%), Gaps = 4/147 (2%)
Query: 20 FKDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQQKVLHETIKV 79
+K+ +LKE + ++ +K L + E Q + +K+ HE K+
Sbjct: 876 YKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKI 935
Query: 80 LEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQ 139
++ R L D + T++ + + + E+ +++L++ E + EE+ ++QL+
Sbjct: 936 GLNKERL-LHDEQS-TDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLR 993
Query: 140 QKIENDQQHQAA--ELECEEDVIPDSP 164
Q+++ +++ A + + EE ++ SP
Sbjct: 994 QELKTVKKNYEALKQRQDEERMVQSSP 1020
>gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo
sapiens]
Length = 693
Score = 45.4 bits (106), Expect = 2e-04
Identities = 51/221 (23%), Positives = 91/221 (41%), Gaps = 27/221 (12%)
Query: 36 QGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQQKVLH---ETIKVLEDRLRAGLCDRC 92
Q LQ + L+++ + + E +N++LREQQK L E ++ E RLR
Sbjct: 337 QRLQEQEEMLREQEVQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRK------ 390
Query: 93 AVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQQKIENDQQHQAAE 152
EE +RK+++ + ++ L + LQ++ ++L+ K++ Q AE
Sbjct: 391 --QEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDK----QLAE 444
Query: 153 LECEEDVIPDSPITAFSF-SGVNRLRRK-ENPHVRYIEQTHTKLEHSVCANEMRKVSKSS 210
+C + + + +A V L+ K + H+ Q + +LE + +
Sbjct: 445 PQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQQNQQLETQLSLVALPGEGDGG 504
Query: 211 TH--------PQHNPNENEILVADTYDQS--QSPMAKAHGT 241
H P+ PN E L + S P KA GT
Sbjct: 505 QHLDSEEEEAPRPTPNIPEDLESREATSSFMDLPKEKADGT 545
Score = 41.6 bits (96), Expect = 0.003
Identities = 44/183 (24%), Positives = 89/183 (48%), Gaps = 15/183 (8%)
Query: 33 REVQGLQVKV-TKLKQERILDAQRLEEFFTKNQQLREQQKVLHETIKVLEDRLRAGLCDR 91
+EV+GL+ K+ ++++ + L E+ Q+L+EQ+++L E +V R + LC++
Sbjct: 309 QEVEGLEGKLQSQVENNQALSLLSKEQ----KQRLQEQEEMLREQ-EVQRVREQERLCEQ 363
Query: 92 CAVTEEHMRKKQQEFENIRQQNLKLITE---LMNERNTLQEENKKLSEQLQQ--KIENDQ 146
E + Q++ E +R+Q +L + L E LQ++ K+L +Q ++ K E
Sbjct: 364 NERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERL 423
Query: 147 QHQAAELECEEDVIPDSPIT--AFSFSGVNRLRRKENPHVRYIEQTHTKL--EHSVCANE 202
Q Q L ++ D + SF +N ++ + +++ KL EH A++
Sbjct: 424 QKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQ 483
Query: 203 MRK 205
+
Sbjct: 484 QNQ 486
Score = 39.7 bits (91), Expect = 0.012
Identities = 61/286 (21%), Positives = 119/286 (41%), Gaps = 51/286 (17%)
Query: 38 LQVKVTKLKQERILDAQRLEEFFT-----KNQ-----------------QLREQQKVLHE 75
+ V+ LK+E+ D R++E KNQ QL+++ K L +
Sbjct: 250 MSVEARTLKEEKKRDIHRIQELERSLSELKNQMAKPPSLAPPAVTSVVEQLQDEAKHLRQ 309
Query: 76 TIKVLEDRLRAGLCDRCA---VTEEHMRKKQQEFENIRQQNLKLITE---LMNERNTLQE 129
++ LE +L++ + + A +++E ++ Q++ E +R+Q ++ + E L + L+E
Sbjct: 310 EVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEVQRVREQERLCEQNERLRE 369
Query: 130 ENKKLSEQLQ--QKIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRRKENPHVRYI 187
+ K L EQ + +K E + Q L EE+ + + RL +K
Sbjct: 370 QQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQE--ERLWKK-------- 419
Query: 188 EQTHTKLEHSVCANEMRKVSKSSTHPQ------HNPNENEILVADTYDQSQSPMAKAH-G 240
E+ K E + ++ K+ K PQ +N ++ + + + Q + + H
Sbjct: 420 EERLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLE 479
Query: 241 TSSYTPDKSSFNLATVVAETLGLGVQ----EESETQGPMSPLGDEL 282
+S + L+ V G G Q EE E P + ++L
Sbjct: 480 AASQQNQQLETQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDL 525
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 45.1 bits (105), Expect = 3e-04
Identities = 153/797 (19%), Positives = 308/797 (38%), Gaps = 146/797 (18%)
Query: 32 DREVQGLQVKVTKLKQ---ERILDAQRLEEFFTKNQQLREQQKVLHETIKVLEDRLRAGL 88
+++V LQ+K+++L++ E++ ++ L+ K +Q ++Q+ L ++ +LR
Sbjct: 452 EQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTA---KLREAQ 508
Query: 89 CDRCAVTEEHMRKKQ--QEFENIRQQNLKLITELMNER-----------------NTLQE 129
D V + K Q Q E + Q++ + I+ L ER N LQE
Sbjct: 509 NDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQE 568
Query: 130 ENKKLSEQLQQKIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRRKENPHVRYIEQ 189
+N L EQ+ Q E + + + +E+ ++ +++ H+R +
Sbjct: 569 KNHTLQEQVTQLTEKLKNQSESHKQAQEN--------------LHDQVQEQKAHLRAAQD 614
Query: 190 THTKLEHSVCANEMRKVSKSSTHPQHNPNENEILVADTYDQSQSPMAKAHGTSSYTPDKS 249
LE SV NE+ + Q N ++ ++ D ++++ + + ++ T ++
Sbjct: 615 RVLSLETSV--NEL--------NSQLNESKEKVSQLDIQIKAKTELLLS-AEAAKTAQRA 663
Query: 250 SFNLATVVAETLGLGVQEE-----SETQGPMSPLGDELYHCLEGNHKKQPFEESTRNTED 304
A+ Q+E ++ + L D+ HC + + ++E + E
Sbjct: 664 DLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQ 723
Query: 305 SLRFSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDLNTSLSPSLLQPGKKKHLKTLPF 364
+ K + L + S A ++ LNT L + K+ ++
Sbjct: 724 KTEELEGQIKKLEADSLEVKASKE--QALQDLQQQRQLNTDLELRATELSKQLEMEKEIV 781
Query: 365 SNTCISRLEKTRSKSEDSALFTHHSLGSEVNKIIIQSSNKQILINKNISESLGEQNRTEY 424
S+T RL+ + KSE +L S K+ Q KQIL K E+L ++ + ++
Sbjct: 782 SST---RLD-LQKKSE--------ALESIKQKLTKQEEEKQIL--KQDFETLSQETKIQH 827
Query: 425 GKDSNTDKHLEPLKSLGGRTSKRKKTEEESEHEVSCPQASFDKENAFPFPMDNQFSMNGD 484
+ +N +++ K K +E E+S + K + ++F
Sbjct: 828 EELNNR------IQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQ 881
Query: 485 CVMDKPLDLSDRFSAIQRQEKSQGSETSKNKFRQVTLYEALKTIPKGFSSSRKASDGNCT 544
LDL ++ Q + Q T K + K + K ++AS
Sbjct: 882 KGKAAILDLEKTCKELKHQLQVQMENTLKEQ----------KELKKSLEKEKEASH-QLK 930
Query: 545 LPKDSPGEPCSQECIILQPLNKCSPDNKPSLQIKEENAVFKIPLRPRESLETENVLDDIK 604
L +S E ++Q N + K Q++ K ++ + E + ++K
Sbjct: 931 LELNSMQEQ------LIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKK-QIEALQGELK 983
Query: 605 SA---GSHEPIKIQTRSDHGGCELASVLQLNPCRTGKIKSLQNNQDVS---FENIQWSI- 657
A + K+Q + ELA+ + KI LQNN + S F+ +Q
Sbjct: 984 IAVLQKTELENKLQQQLTQAAQELAAEKE-------KISVLQNNYEKSQETFKQLQSDFY 1036
Query: 658 DPGADLSQYKMDVTVIDTK--------------DGSQSKLGGETVDMDCTLVSETVLLKM 703
++L + D+ ++ K G+Q+KL E TL ++ +
Sbjct: 1037 GRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQ 1096
Query: 704 KKQEQ-------KGEKSSNEERKMNDSLEDMFDRTTHEEYESCLADSFSQAADEEEELST 756
+ QE+ + EKS E+ +N+ +S LA+ +E+E++
Sbjct: 1097 QLQERCKALQDIQKEKSLKEKELVNE--------------KSKLAEIEEIKCRQEKEITK 1142
Query: 757 ATKKLHTHGDKQDKVKQ 773
++L +H K + +K+
Sbjct: 1143 LNEELKSH--KLESIKE 1157
Score = 30.8 bits (68), Expect = 5.7
Identities = 31/122 (25%), Positives = 56/122 (45%), Gaps = 7/122 (5%)
Query: 33 REVQGLQVKVTKLKQERILDAQRL---EEFFTKNQQLREQQKVLHETIKVL---EDRLRA 86
+E+Q L+ V +L Q+ + L E+ +TK ++ ++ V + I+ +D
Sbjct: 288 QELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQ 347
Query: 87 GLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQQKIENDQ 146
L R + +E + + E + KL EL +E T + K +QLQQ+ E +
Sbjct: 348 QLQSRLSASETSLHRIHVELSEKGEATQKLKEEL-SEVETKYQHLKAEFKQLQQQREEKE 406
Query: 147 QH 148
QH
Sbjct: 407 QH 408
>gi|149999352 forkhead box P2 isoform II [Homo sapiens]
Length = 740
Score = 44.7 bits (104), Expect = 4e-04
Identities = 35/177 (19%), Positives = 77/177 (43%), Gaps = 22/177 (12%)
Query: 6 SSCGSPNSADTSSDFKDLWTKLKEC---------HDREVQGLQVKVT------------- 43
S SP S+D ++L + K C H + V V
Sbjct: 71 SGLKSPKSSDKQRPLQELLPETKLCICGHSSGDGHPHNTFAVPVSVAMMTPQVITPQQMQ 130
Query: 44 KLKQERILDAQRLEEFFTKNQQLREQQKVLHETIKVLEDRLRAGLCDRCAVTEEHMRKKQ 103
++ Q+++L Q+L+ + Q + QQ+ L E K +++L L + ++ +++Q
Sbjct: 131 QILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQ 190
Query: 104 QEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQQKIENDQQHQAAELECEEDVI 160
Q+ + +QQ + + ++ Q+ K +++ QQ+ + QQ A +L ++ ++
Sbjct: 191 QQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLL 247
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 44.7 bits (104), Expect = 4e-04
Identities = 78/380 (20%), Positives = 154/380 (40%), Gaps = 51/380 (13%)
Query: 23 LWTKLKEC-----HDREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQQKVLHETI 77
L+TK+K + E+Q + ++ K K+ + L+E K+ QL E++ +L E +
Sbjct: 837 LFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQL 896
Query: 78 KVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQ 137
+ E L A + K+QE E I + + E + LQ E KK+++Q
Sbjct: 897 QA-ETELYA----EAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQ 951
Query: 138 LQQKIENDQQHQAAELECE-EDVIPDSPITAF--SFSGVNRLRRKENPHVRYIEQTHTKL 194
+ E ++ +AA + + E V ++ I ++ K + + +E+ + L
Sbjct: 952 MLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDL 1011
Query: 195 EHSVCANEMRKVSKSSTHPQHNPNENEILV-ADTYDQSQSPMAKAHGTSSYTPDKSSFN- 252
++ E + + + +H +E+ V ++S+ + K D S F+
Sbjct: 1012 TTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKL--KRKLEGDASDFHE 1069
Query: 253 -LATVVAETLGLGVQ---EESETQGPMSPLGDEL---------YHCLEGN----HKKQPF 295
+A + A+ L +Q +E E Q ++ L DE+ LEG+ +
Sbjct: 1070 QIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDS 1129
Query: 296 EESTRNTEDSLR-------------FSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDL 342
E + RN + + D+ T Q+EL + V + +K LD
Sbjct: 1130 ERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEV----TVLKKALDE 1185
Query: 343 NTSLSPSLLQPGKKKHLKTL 362
T + +Q ++KH + +
Sbjct: 1186 ETRSHEAQVQEMRQKHAQAV 1205
Score = 33.9 bits (76), Expect = 0.67
Identities = 31/138 (22%), Positives = 67/138 (48%), Gaps = 10/138 (7%)
Query: 21 KDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQQKVLHETIKVL 80
K L LK+ + ++ + +KQ R L AQ +++F + + R + + T K
Sbjct: 1620 KKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQ-MKDFQRELEDARASRDEIFATAKEN 1678
Query: 81 EDRLRAGLCDRCAVTEE----HMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLS- 135
E + ++ D + E+ +KQ + E +++ + + ++ RN LQ+E ++L
Sbjct: 1679 EKKAKSLEADLMQLQEDLAAAERARKQADLE--KEELAEELASSLSGRNALQDEKRRLEA 1736
Query: 136 --EQLQQKIENDQQHQAA 151
QL++++E +Q + A
Sbjct: 1737 RIAQLEEELEEEQGNMEA 1754
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 44.7 bits (104), Expect = 4e-04
Identities = 78/380 (20%), Positives = 154/380 (40%), Gaps = 51/380 (13%)
Query: 23 LWTKLKEC-----HDREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQQKVLHETI 77
L+TK+K + E+Q + ++ K K+ + L+E K+ QL E++ +L E +
Sbjct: 844 LFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQL 903
Query: 78 KVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQ 137
+ E L A + K+QE E I + + E + LQ E KK+++Q
Sbjct: 904 QA-ETELYA----EAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQ 958
Query: 138 LQQKIENDQQHQAAELECE-EDVIPDSPITAF--SFSGVNRLRRKENPHVRYIEQTHTKL 194
+ E ++ +AA + + E V ++ I ++ K + + +E+ + L
Sbjct: 959 MLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDL 1018
Query: 195 EHSVCANEMRKVSKSSTHPQHNPNENEILV-ADTYDQSQSPMAKAHGTSSYTPDKSSFN- 252
++ E + + + +H +E+ V ++S+ + K D S F+
Sbjct: 1019 TTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKL--KRKLEGDASDFHE 1076
Query: 253 -LATVVAETLGLGVQ---EESETQGPMSPLGDEL---------YHCLEGN----HKKQPF 295
+A + A+ L +Q +E E Q ++ L DE+ LEG+ +
Sbjct: 1077 QIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDS 1136
Query: 296 EESTRNTEDSLR-------------FSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDL 342
E + RN + + D+ T Q+EL + V + +K LD
Sbjct: 1137 ERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEV----TVLKKALDE 1192
Query: 343 NTSLSPSLLQPGKKKHLKTL 362
T + +Q ++KH + +
Sbjct: 1193 ETRSHEAQVQEMRQKHAQAV 1212
Score = 33.9 bits (76), Expect = 0.67
Identities = 31/138 (22%), Positives = 67/138 (48%), Gaps = 10/138 (7%)
Query: 21 KDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQQKVLHETIKVL 80
K L LK+ + ++ + +KQ R L AQ +++F + + R + + T K
Sbjct: 1627 KKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQ-MKDFQRELEDARASRDEIFATAKEN 1685
Query: 81 EDRLRAGLCDRCAVTEE----HMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLS- 135
E + ++ D + E+ +KQ + E +++ + + ++ RN LQ+E ++L
Sbjct: 1686 EKKAKSLEADLMQLQEDLAAAERARKQADLE--KEELAEELASSLSGRNALQDEKRRLEA 1743
Query: 136 --EQLQQKIENDQQHQAA 151
QL++++E +Q + A
Sbjct: 1744 RIAQLEEELEEEQGNMEA 1761
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 44.7 bits (104), Expect = 4e-04
Identities = 78/380 (20%), Positives = 154/380 (40%), Gaps = 51/380 (13%)
Query: 23 LWTKLKEC-----HDREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQQKVLHETI 77
L+TK+K + E+Q + ++ K K+ + L+E K+ QL E++ +L E +
Sbjct: 844 LFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQL 903
Query: 78 KVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQ 137
+ E L A + K+QE E I + + E + LQ E KK+++Q
Sbjct: 904 QA-ETELYA----EAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQ 958
Query: 138 LQQKIENDQQHQAAELECE-EDVIPDSPITAF--SFSGVNRLRRKENPHVRYIEQTHTKL 194
+ E ++ +AA + + E V ++ I ++ K + + +E+ + L
Sbjct: 959 MLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDL 1018
Query: 195 EHSVCANEMRKVSKSSTHPQHNPNENEILV-ADTYDQSQSPMAKAHGTSSYTPDKSSFN- 252
++ E + + + +H +E+ V ++S+ + K D S F+
Sbjct: 1019 TTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKL--KRKLEGDASDFHE 1076
Query: 253 -LATVVAETLGLGVQ---EESETQGPMSPLGDEL---------YHCLEGN----HKKQPF 295
+A + A+ L +Q +E E Q ++ L DE+ LEG+ +
Sbjct: 1077 QIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDS 1136
Query: 296 EESTRNTEDSLR-------------FSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDL 342
E + RN + + D+ T Q+EL + V + +K LD
Sbjct: 1137 ERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEV----TVLKKALDE 1192
Query: 343 NTSLSPSLLQPGKKKHLKTL 362
T + +Q ++KH + +
Sbjct: 1193 ETRSHEAQVQEMRQKHAQAV 1212
Score = 33.9 bits (76), Expect = 0.67
Identities = 31/138 (22%), Positives = 67/138 (48%), Gaps = 10/138 (7%)
Query: 21 KDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQQKVLHETIKVL 80
K L LK+ + ++ + +KQ R L AQ +++F + + R + + T K
Sbjct: 1627 KKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQ-MKDFQRELEDARASRDEIFATAKEN 1685
Query: 81 EDRLRAGLCDRCAVTEE----HMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLS- 135
E + ++ D + E+ +KQ + E +++ + + ++ RN LQ+E ++L
Sbjct: 1686 EKKAKSLEADLMQLQEDLAAAERARKQADLE--KEELAEELASSLSGRNALQDEKRRLEA 1743
Query: 136 --EQLQQKIENDQQHQAA 151
QL++++E +Q + A
Sbjct: 1744 RIAQLEEELEEEQGNMEA 1761
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 44.7 bits (104), Expect = 4e-04
Identities = 78/380 (20%), Positives = 154/380 (40%), Gaps = 51/380 (13%)
Query: 23 LWTKLKEC-----HDREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQQKVLHETI 77
L+TK+K + E+Q + ++ K K+ + L+E K+ QL E++ +L E +
Sbjct: 837 LFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQL 896
Query: 78 KVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQ 137
+ E L A + K+QE E I + + E + LQ E KK+++Q
Sbjct: 897 QA-ETELYA----EAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQ 951
Query: 138 LQQKIENDQQHQAAELECE-EDVIPDSPITAF--SFSGVNRLRRKENPHVRYIEQTHTKL 194
+ E ++ +AA + + E V ++ I ++ K + + +E+ + L
Sbjct: 952 MLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDL 1011
Query: 195 EHSVCANEMRKVSKSSTHPQHNPNENEILV-ADTYDQSQSPMAKAHGTSSYTPDKSSFN- 252
++ E + + + +H +E+ V ++S+ + K D S F+
Sbjct: 1012 TTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKL--KRKLEGDASDFHE 1069
Query: 253 -LATVVAETLGLGVQ---EESETQGPMSPLGDEL---------YHCLEGN----HKKQPF 295
+A + A+ L +Q +E E Q ++ L DE+ LEG+ +
Sbjct: 1070 QIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDS 1129
Query: 296 EESTRNTEDSLR-------------FSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDL 342
E + RN + + D+ T Q+EL + V + +K LD
Sbjct: 1130 ERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEV----TVLKKALDE 1185
Query: 343 NTSLSPSLLQPGKKKHLKTL 362
T + +Q ++KH + +
Sbjct: 1186 ETRSHEAQVQEMRQKHAQAV 1205
Score = 33.9 bits (76), Expect = 0.67
Identities = 31/138 (22%), Positives = 67/138 (48%), Gaps = 10/138 (7%)
Query: 21 KDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQQKVLHETIKVL 80
K L LK+ + ++ + +KQ R L AQ +++F + + R + + T K
Sbjct: 1620 KKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQ-MKDFQRELEDARASRDEIFATAKEN 1678
Query: 81 EDRLRAGLCDRCAVTEE----HMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLS- 135
E + ++ D + E+ +KQ + E +++ + + ++ RN LQ+E ++L
Sbjct: 1679 EKKAKSLEADLMQLQEDLAAAERARKQADLE--KEELAEELASSLSGRNALQDEKRRLEA 1736
Query: 136 --EQLQQKIENDQQHQAA 151
QL++++E +Q + A
Sbjct: 1737 RIAQLEEELEEEQGNMEA 1754
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 44.3 bits (103), Expect = 5e-04
Identities = 45/186 (24%), Positives = 88/186 (47%), Gaps = 15/186 (8%)
Query: 35 VQGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQQ-KVLHETIKVLEDRLRAGLCDRCA 93
+ L++K+ + ++ L+ +++ L E+ K+L ET+ E LR LC +
Sbjct: 1358 IDQLKIKLQDSQNNLQINVSELQTLQSEHDTLLERHNKMLQETVSK-EAELREKLC---S 1413
Query: 94 VTEEHMRKKQQEFENIRQ---QNLKLITELMNERNTLQEENKKLSEQLQQKIENDQQHQA 150
+ E+M K + + + Q QN L ++ LQEE++K E LQQ++ + +A
Sbjct: 1414 IQSENMMMKSEHTQTVSQLTSQNEVLRNSFRDQVRHLQEEHRKTVETLQQQL---SKMEA 1470
Query: 151 AELECEEDVIPDSPITAFSFSGVNRLRRKENPHVRYIE-QTHTKLE-HSVCANEMRKVSK 208
+ + + SP++ S + LR + N + ++ T T+ E + + VS
Sbjct: 1471 QLFQLKNEPTTRSPVS--SQQSLKNLRERRNTDLPLLDMHTVTREEGEGMETTDTESVSS 1528
Query: 209 SSTHPQ 214
+ST+ Q
Sbjct: 1529 ASTYTQ 1534
Score = 38.9 bits (89), Expect = 0.021
Identities = 41/182 (22%), Positives = 83/182 (45%), Gaps = 33/182 (18%)
Query: 29 ECHDREVQGL----QVKVTKLKQERILDAQR-----------LEEFFTKNQQLREQQKVL 73
E H+REVQ L Q ++++L + + D+++ L+E QQ +++ +
Sbjct: 420 EQHNREVQSLKEQHQKEISELNETFLSDSEKEKLTLMFEIQGLKEQCENLQQEKQEAILN 479
Query: 74 HETIKVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKK 133
+E+++ + + L+ L E K QEFE+++QQ + EL + T E
Sbjct: 480 YESLREIMEILQTEL-------GESAGKISQEFESMKQQQASDVHELQQKLRTAFTEKDA 532
Query: 134 LSEQLQQKIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRRKENPHVRYIEQTHTK 193
L E + N Q + +L +++++P+ T + L+ K ++ + Q T
Sbjct: 533 LLETV-----NRLQGENEKLLSQQELVPELENT------IKNLQEKNGVYLLSLSQRDTM 581
Query: 194 LE 195
L+
Sbjct: 582 LK 583
Score = 35.0 bits (79), Expect = 0.30
Identities = 32/141 (22%), Positives = 63/141 (44%), Gaps = 26/141 (18%)
Query: 15 DTSSDFKDLWTKLKECHD---REVQGLQVKV----TKLKQERILDAQRLEEFFTKNQQLR 67
D+ + D +L++ H +E++ L+ ++ +K +++ ++LEE +L
Sbjct: 108 DSVTKMGDAHKELEQSHINYVKEIENLKNELMAVRSKYSEDKANLQKQLEEAMNTQLELS 167
Query: 68 EQQKVLHETIKVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTL 127
EQ K + + E++++K Q+E E IR + I L + +
Sbjct: 168 EQLKFQNNS-------------------EDNVKKLQEEIEKIRPGFEEQILYLQKQLDAT 208
Query: 128 QEENKKLSEQLQQKIENDQQH 148
+E K+ QLQ IE + QH
Sbjct: 209 TDEKKETVTQLQNIIEANSQH 229
Score = 32.3 bits (72), Expect = 1.9
Identities = 35/147 (23%), Positives = 71/147 (48%), Gaps = 30/147 (20%)
Query: 15 DTSSDFKDLWTKL----KECHDREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQQ 70
D S K+L K+ KEC ++E + ++K+ +K ++ LD+ R E Q ++E+
Sbjct: 941 DPLSSVKELEEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKE-----TQTVKEEL 995
Query: 71 KVLHETIKVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEE 130
E+++ +D+L A + D E + +NL L E +E+ +++E
Sbjct: 996 ----ESLRSEKDQLSASMRDLIQGAESY-------------KNLLLEYEKQSEQLDVEKE 1038
Query: 131 NKKLSEQLQQKIEN-DQQHQAAELECE 156
+ + +IE+ +Q + + L+CE
Sbjct: 1039 R---ANNFEHRIEDLTRQLRNSTLQCE 1062
Score = 31.6 bits (70), Expect = 3.3
Identities = 34/157 (21%), Positives = 67/157 (42%), Gaps = 16/157 (10%)
Query: 49 RILDAQRLEEFFTKNQQLREQQKVLHETIKVLEDRLRAGLCDRCAVTEEHMRKKQQEFEN 108
++L+ +++++ F K Q +++ E V ED + + E + K +E N
Sbjct: 743 KLLENEQVQKLFVKTQLYGFLKEMGSE---VSEDSEEKDVVNVLQAVGESLAKINEEKCN 799
Query: 109 IRQQNLKLITELMNERNTLQEENKKLSEQLQQKIENDQQH------QAAELECEEDVIPD 162
+ Q + + EL E LQEE+ E+L+ + + +Q + E++ E++ +
Sbjct: 800 LAFQRDEKVLELEKEIKCLQEESVVQCEELKSLLRDYEQEKVLLRKELEEIQSEKEALQS 859
Query: 163 SPITAFSFSGVNRLRRKENPH----VRYIEQTHTKLE 195
N R EN + V + QT +K E
Sbjct: 860 D---LLEMKNANEKTRLENQNLLIQVEEVSQTCSKSE 893
Score = 30.4 bits (67), Expect = 7.4
Identities = 44/164 (26%), Positives = 73/164 (44%), Gaps = 31/164 (18%)
Query: 9 GSPNSADTSSDFKDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLRE 68
G NS D D KLK H+ E+ K + ++ + +++E+ N +L
Sbjct: 587 GKINSLTEEKD--DFINKLKNSHE-EMDNFHKKCEREERLILELGKKVEQTIQYNSEL-- 641
Query: 69 QQKVLHETIKVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQ--NLKLITE----LMN 122
+QKV + L GL EE +++K Q + + + +K+++E L
Sbjct: 642 EQKV---------NELTGGL-------EETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSA 685
Query: 123 ERNTLQEENKKLSEQLQQKIENDQQHQAAELECEEDVIPDSPIT 166
E +L EEN KLS + +Q + D + L +EDVI IT
Sbjct: 686 EVKSLYEENNKLSSEKKQ-LSRDLE---VFLSQKEDVILKEHIT 725
>gi|59806361 hypothetical protein LOC387104 [Homo sapiens]
Length = 947
Score = 44.3 bits (103), Expect = 5e-04
Identities = 67/296 (22%), Positives = 124/296 (41%), Gaps = 33/296 (11%)
Query: 6 SSCGSPNSADTSSDFKDLWTKLKECHDREVQGLQVKVTKLKQERILDAQR---LEEFFTK 62
SS P + ++ KL+E E + L+ ++ +L+ E +D R EE +
Sbjct: 338 SSQPHPQQLQEQEEMQEEMEKLRE----ENETLKNEIDELRTE--MDEMRDTFFEEDACQ 391
Query: 63 NQQLREQQKVLHETIKVLEDRLRAGLCDRCAVTE------EHMRKKQQEFENIRQQNLKL 116
Q++R + + ++ ++L+ RLR R + E +R +Q+ + + +++L
Sbjct: 392 LQEMRHELERANKNCRILQYRLRKAERKRLRYAQTGEIDGELLRSLEQDLKVAKDVSVRL 451
Query: 117 ITELMN---ERNTLQEENKKLSEQL------QQKIENDQQHQAAELECEEDVIPDSPITA 167
EL N +R T ++EN+KL +QL +Q ++N+ + + EL + D P
Sbjct: 452 HHELENVEEKRTTTEDENEKLRQQLIEVEIAKQALQNELE-KMKELSLKRRGSKDLP--- 507
Query: 168 FSFSGVNRLRRKENPHVRYIEQTHTKLEHSVCANEMRKVSKSSTHPQHNPNENEILVADT 227
S + +E+ + K E ++ +M K+ K +H + D
Sbjct: 508 KSEKKAQQTPTEEDNEDLKCQLQFVKEEAALMRKKMAKIDKEKDRFEHELQKYRSFYGDL 567
Query: 228 YDQSQSPMAKAHGTSSYTPDKSSFNLATVVAETLGLG---VQEESETQGPMSPLGD 280
S P +A G S + L V E LG V+ E E +G + L D
Sbjct: 568 --DSPLPKGEAGGPPSTREAELKLRLRLVEEEANILGRKIVELEVENRGLKAELDD 621
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 44.3 bits (103), Expect = 5e-04
Identities = 99/488 (20%), Positives = 188/488 (38%), Gaps = 78/488 (15%)
Query: 31 HDREVQGLQVKVTKLKQ---------------ERILDAQRL--EEFFTKNQQLREQQKVL 73
HD ++ LQV++ ++KQ +R L A + +E +N+ L+E+ +
Sbjct: 1450 HDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLA 1509
Query: 74 HETIKVL-------------EDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQN------- 113
TI+ L +++ + + R A+ +E K E + +N
Sbjct: 1510 RGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSC 1569
Query: 114 --LKLITE-LMNERNTLQEENKKL-SEQLQQKIENDQQHQAAELECE------EDVIPDS 163
LKL E L ++ L +E + L S ++ + E ++H+ + E E E+V ++
Sbjct: 1570 ESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEA 1629
Query: 164 PITAFSFSGVNRLRRKENPHVRYIEQTHTKLEHSV---------CANEMRKVSKSSTHP- 213
V + +++ +R E + E + +MRK +KS
Sbjct: 1630 ERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKI 1689
Query: 214 QHNPNENEILVADTY---DQSQSPMAKAHGTSSYTPDKSSFNLATVVAETLGLGVQEESE 270
EN+ L A+ + D ++ M SS K + ETL Q
Sbjct: 1690 LELEEENDRLRAEVHPAGDTAKECMETL--LSSNASMKEELERVKMEYETLSKKFQSLMS 1747
Query: 271 TQGPMSPLGDELYHCLEGNHKKQPFEESTRNTEDSLRFSDSTSKTPP--QEELPTRVSSP 328
+ +S +L H +EGN KQ E+T ++ ++ +++ P EE + S
Sbjct: 1748 EKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSIPGETEEQDSLSMST 1807
Query: 329 VFGATSSIKSGLDLNTSLSPSLLQPGK-KKHLKTLPFSNTCISRLEKTRSK--------- 378
+ S+ S N ++S + +L+ + I+ LE+ + K
Sbjct: 1808 RPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLE 1867
Query: 379 SEDSALFTHHSLGSEVNKIIIQSSNKQILINKNISESLGE----QNRTEYGKDSNTDKHL 434
+E + L + S K++ + K L+N+ I E L + E KD ++ +
Sbjct: 1868 NEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLM 1927
Query: 435 EPLKSLGG 442
L L G
Sbjct: 1928 NQLAELNG 1935
Score = 37.4 bits (85), Expect = 0.061
Identities = 51/221 (23%), Positives = 103/221 (46%), Gaps = 34/221 (15%)
Query: 32 DREVQGLQVK----VTKLK------------QERILD-AQRLEEFFTKNQQLREQQ-KVL 73
D+EVQ LQ VT+L ++R++D A++ E F+ Q +E++ ++
Sbjct: 2170 DKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLK 2229
Query: 74 HETIKVLEDRLRAGLC--DRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEEN 131
+ VL+D+LR + + + +Q +E+ Q ++L ++ + TLQ EN
Sbjct: 2230 EDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCD---TLQGEN 2286
Query: 132 KKLSEQLQQ--KIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRRKENPHVRYIEQ 189
K+L QL++ + + Q++ A+LE E + D +T S + + + + ++ I Q
Sbjct: 2287 KELLSQLEETRHLYHSSQNELAKLESELKSLKDQ-LTDLS-NSLEKCKEQKGNLEGIIRQ 2344
Query: 190 THTKLEHSVCANEMRKVS-------KSSTHPQHNPNENEIL 223
+++S + E + S H + N E +I+
Sbjct: 2345 QEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKII 2385
Score = 37.0 bits (84), Expect = 0.079
Identities = 40/152 (26%), Positives = 65/152 (42%), Gaps = 22/152 (14%)
Query: 16 TSSDFKDLWTKLKECHDRE-VQGLQVKVTKLKQER---ILDAQRLEEFFTKNQQLREQQK 71
+ + F D++ + + E + LQ +V +L+ E+ +L + LEE +N++L Q
Sbjct: 450 SQTSFPDVYNEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQ-- 507
Query: 72 VLHETIKVLEDRLRAGLCDR-----CAVTEEHMRKKQQE------FENIRQQNLKLITEL 120
I +LE + R G DR V + R E EN Q K ++ L
Sbjct: 508 -----ITLLEAQNRTGEADREVSEISIVDIANKRSSSAEESGQDVLENTFSQKHKELSVL 562
Query: 121 MNERNTLQEENKKLSEQLQQKIENDQQHQAAE 152
+ E QEE L QLQ K + H+ +
Sbjct: 563 LLEMKEAQEEIAFLKLQLQGKRAEEADHEVLD 594
Score = 36.6 bits (83), Expect = 0.10
Identities = 39/188 (20%), Positives = 85/188 (45%), Gaps = 19/188 (10%)
Query: 26 KLKECHDREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQQKVLHETIKVLEDRLR 85
+L++ HD+E++ L+ +++ ++E I+ + ++ K QL E K TIK + +
Sbjct: 2401 ELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLK----TIKKENIQQK 2456
Query: 86 AGLC-----------DRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKL 134
A L DR + ++ + +++ I +++ +LI E E N L+EE + L
Sbjct: 2457 AQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKD-QLIQEAAAENNKLKEEIRGL 2515
Query: 135 SEQLQQKIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRRKENPHVRYIEQTHTKL 194
+ + + A ++ ED+ + + S +L + + +E + KL
Sbjct: 2516 RSHMDDLNSENAKLDAELIQYREDL---NQVITIKDSQQKQLLEVQLQQNKELENKYAKL 2572
Query: 195 EHSVCANE 202
E + +E
Sbjct: 2573 EEKLKESE 2580
Score = 35.0 bits (79), Expect = 0.30
Identities = 38/130 (29%), Positives = 62/130 (47%), Gaps = 17/130 (13%)
Query: 22 DLWTKLKECHDREVQGLQVKVTKLKQERILDAQ-RLEEFFTKNQQLREQQKVLHETIKVL 80
DL L++C +E +G + + ++ I +++ E+ T Q RE LHE I +
Sbjct: 2323 DLSNSLEKC--KEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMK 2380
Query: 81 EDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMN-------ERNTLQEENKK 133
E ++ + L + EE + Q +RQQ+ K I EL N E L+EENKK
Sbjct: 2381 EQKIISLLSGK----EEAI---QVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKK 2433
Query: 134 LSEQLQQKIE 143
++ Q +E
Sbjct: 2434 AVDKTNQLME 2443
Score = 33.9 bits (76), Expect = 0.67
Identities = 41/183 (22%), Positives = 78/183 (42%), Gaps = 35/183 (19%)
Query: 12 NSADTSSDFKDLWTKLKECHDREVQGLQVKVTKLKQERILDAQ-RLEEFFTKNQQLREQ- 69
+S + + + + KL+E + + LQ ++T+ + E+ + +EEF QQL+E+
Sbjct: 138 SSTEEEMEIEKIKHKLQE-KEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKE 196
Query: 70 -------------------QKVLHET-------IKVLEDRLRAGLCDRCAVTEEH----- 98
Q+V+ E +++ ED L + TE
Sbjct: 197 EFISTLQAQLSQTQAEQAAQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRV 256
Query: 99 MRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQQ-KIENDQQHQAAELECEE 157
+++K +E E +++ L E ++ N+ LS+QLQQ + E++ E E EE
Sbjct: 257 LQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREE 316
Query: 158 DVI 160
I
Sbjct: 317 SKI 319
>gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo
sapiens]
Length = 693
Score = 43.9 bits (102), Expect = 6e-04
Identities = 51/221 (23%), Positives = 90/221 (40%), Gaps = 27/221 (12%)
Query: 36 QGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQQKVLH---ETIKVLEDRLRAGLCDRC 92
Q LQ + L+++ + E +N++LREQQK L E ++ E RLR
Sbjct: 337 QRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRK------ 390
Query: 93 AVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQQKIENDQQHQAAE 152
EE +RK+++ + ++ L + LQ++ ++L+ K++ Q AE
Sbjct: 391 --QEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDK----QLAE 444
Query: 153 LECEEDVIPDSPITAFSF-SGVNRLRRK-ENPHVRYIEQTHTKLEHSVCANEMRKVSKSS 210
+C + + + +A V L+ K + H+ Q + +LE + +
Sbjct: 445 PQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQRNQQLETQLSLVALPGEGDGG 504
Query: 211 TH--------PQHNPNENEILVADTYDQS--QSPMAKAHGT 241
H P+ PN E L + S P KA GT
Sbjct: 505 QHLDSEEEEAPRPTPNIPEDLESREATSSFMDLPKEKADGT 545
Score = 38.9 bits (89), Expect = 0.021
Identities = 61/286 (21%), Positives = 118/286 (41%), Gaps = 51/286 (17%)
Query: 38 LQVKVTKLKQERILDAQRLEEFFT-----KNQ-----------------QLREQQKVLHE 75
+ V+ LK+E+ D R++E KNQ QL+++ K L +
Sbjct: 250 MSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQ 309
Query: 76 TIKVLEDRLRAGLCDRCA---VTEEHMRKKQQEFENIRQQNLKLITE---LMNERNTLQE 129
++ LE +L++ + + A +++E ++ Q++ E +R+Q + + E L + L+E
Sbjct: 310 EVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLRE 369
Query: 130 ENKKLSEQLQ--QKIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRRKENPHVRYI 187
+ K L EQ + +K E + Q L EE+ + + RL +K
Sbjct: 370 QQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQE--ERLWKK-------- 419
Query: 188 EQTHTKLEHSVCANEMRKVSKSSTHPQ------HNPNENEILVADTYDQSQSPMAKAH-G 240
E+ K E + ++ K+ K PQ +N ++ + + + Q + + H
Sbjct: 420 EERLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLE 479
Query: 241 TSSYTPDKSSFNLATVVAETLGLGVQ----EESETQGPMSPLGDEL 282
+S + L+ V G G Q EE E P + ++L
Sbjct: 480 AASQRNQQLETQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDL 525
>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
Length = 715
Score = 43.9 bits (102), Expect = 6e-04
Identities = 24/120 (20%), Positives = 63/120 (52%)
Query: 41 KVTKLKQERILDAQRLEEFFTKNQQLREQQKVLHETIKVLEDRLRAGLCDRCAVTEEHMR 100
++ ++ Q+++L Q+L+ + Q + QQ+ L E K +++L L + ++ +
Sbjct: 103 QMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQ 162
Query: 101 KKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQQKIENDQQHQAAELECEEDVI 160
++QQ+ + +QQ + + ++ Q+ K +++ QQ+ + QQ A +L ++ ++
Sbjct: 163 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLL 222
Score = 30.4 bits (67), Expect = 7.4
Identities = 23/98 (23%), Positives = 52/98 (53%), Gaps = 9/98 (9%)
Query: 64 QQLREQQKVLHETIKVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNE 123
QQ+ +QQ + + ++ L + +A + + + E + KKQQE Q +L+L+ + +
Sbjct: 105 QQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFY--KKQQE-----QLHLQLLQQQQQQ 157
Query: 124 RNTLQEENKKLSEQLQQKIENDQQHQAAELECEEDVIP 161
+ Q++ ++ +Q QQ+ + QQ Q + + ++ P
Sbjct: 158 QQ--QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHP 193
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.127 0.355
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,302,238
Number of Sequences: 37866
Number of extensions: 1556177
Number of successful extensions: 8234
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 72
Number of HSP's successfully gapped in prelim test: 600
Number of HSP's that attempted gapping in prelim test: 6468
Number of HSP's gapped (non-prelim): 2134
length of query: 867
length of database: 18,247,518
effective HSP length: 111
effective length of query: 756
effective length of database: 14,044,392
effective search space: 10617560352
effective search space used: 10617560352
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.