BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|126352446 elastin isoform d precursor [Homo sapiens] (711 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|126352446 elastin isoform d precursor [Homo sapiens] 1420 0.0 gi|126352440 elastin isoform a precursor [Homo sapiens] 1393 0.0 gi|126352322 elastin isoform c precursor [Homo sapiens] 1375 0.0 gi|126352608 elastin isoform e precursor [Homo sapiens] 1347 0.0 gi|126352700 elastin isoform b precursor [Homo sapiens] 1330 0.0 gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 180 4e-45 gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 176 7e-44 gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] 176 9e-44 gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s... 169 8e-42 gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa... 169 8e-42 gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s... 169 8e-42 gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo ... 167 2e-41 gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo s... 167 2e-41 gi|48762934 alpha 2 type I collagen [Homo sapiens] 166 5e-41 gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 162 1e-39 gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 162 1e-39 gi|116256354 alpha 2 type IV collagen preproprotein [Homo sapiens] 160 4e-39 gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 153 5e-37 gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] 150 5e-36 gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens] 145 1e-34 gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens] 145 1e-34 gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 144 4e-34 gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens] 143 5e-34 gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 141 2e-33 gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 141 2e-33 gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho... 141 2e-33 gi|18105032 type X collagen alpha 1 precursor [Homo sapiens] 141 2e-33 gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens] 140 4e-33 gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens] 139 9e-33 gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] 139 1e-32 >gi|126352446 elastin isoform d precursor [Homo sapiens] Length = 711 Score = 1420 bits (3677), Expect = 0.0 Identities = 711/711 (100%), Positives = 711/711 (100%) Query: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG 60 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG Sbjct: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG 60 Query: 61 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 120 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG Sbjct: 61 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 120 Query: 121 LGVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV 180 LGVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV Sbjct: 121 LGVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV 180 Query: 181 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV 240 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV Sbjct: 181 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV 240 Query: 241 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI 300 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI Sbjct: 241 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI 300 Query: 301 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP 360 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP Sbjct: 301 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP 360 Query: 361 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP 420 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP Sbjct: 361 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP 420 Query: 421 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVP 480 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVP Sbjct: 421 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVP 480 Query: 481 GVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVA 540 GVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVA Sbjct: 481 GVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVA 540 Query: 541 AKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKY 600 AKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKY Sbjct: 541 AKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKY 600 Query: 601 GAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL 660 GAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL Sbjct: 601 GAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL 660 Query: 661 GVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPGGACLGKACGRKRK 711 GVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPGGACLGKACGRKRK Sbjct: 661 GVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPGGACLGKACGRKRK 711 >gi|126352440 elastin isoform a precursor [Homo sapiens] Length = 724 Score = 1393 bits (3606), Expect = 0.0 Identities = 706/729 (96%), Positives = 706/729 (96%), Gaps = 23/729 (3%) Query: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG 60 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG Sbjct: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG 60 Query: 61 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 120 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG Sbjct: 61 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 120 Query: 121 LGVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV 180 LGVSA GAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV Sbjct: 121 LGVSA-----GAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV 175 Query: 181 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV 240 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV Sbjct: 176 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV 235 Query: 241 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI 300 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI Sbjct: 236 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI 295 Query: 301 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP 360 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP Sbjct: 296 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP 355 Query: 361 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP 420 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP Sbjct: 356 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP 415 Query: 421 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVP 480 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVP Sbjct: 416 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVP 475 Query: 481 GVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVA 540 GVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVA Sbjct: 476 GVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVA 535 Query: 541 AKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKY 600 AKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKY Sbjct: 536 AKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKY 595 Query: 601 GAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL 660 GAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL Sbjct: 596 GAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL 655 Query: 661 GVPGVGGLGGIPPAAAAKAAKY------------------GVAARPGFGLSPIFPGGACL 702 GVPGVGGLGGIPPAAAAKAAKY GVAARPGFGLSPIFPGGACL Sbjct: 656 GVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGACL 715 Query: 703 GKACGRKRK 711 GKACGRKRK Sbjct: 716 GKACGRKRK 724 >gi|126352322 elastin isoform c precursor [Homo sapiens] Length = 692 Score = 1375 bits (3558), Expect = 0.0 Identities = 692/711 (97%), Positives = 692/711 (97%), Gaps = 19/711 (2%) Query: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG 60 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG Sbjct: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG 60 Query: 61 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 120 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG Sbjct: 61 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 120 Query: 121 LGVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV 180 LGVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV Sbjct: 121 LGVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV 180 Query: 181 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV 240 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV Sbjct: 181 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV 240 Query: 241 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI 300 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI Sbjct: 241 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI 300 Query: 301 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP 360 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP Sbjct: 301 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP 360 Query: 361 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP 420 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP Sbjct: 361 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP 420 Query: 421 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVP 480 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKY GLVP Sbjct: 421 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKY-------------------GLVP 461 Query: 481 GVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVA 540 GVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVA Sbjct: 462 GVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVA 521 Query: 541 AKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKY 600 AKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKY Sbjct: 522 AKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKY 581 Query: 601 GAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL 660 GAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL Sbjct: 582 GAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL 641 Query: 661 GVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPGGACLGKACGRKRK 711 GVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPGGACLGKACGRKRK Sbjct: 642 GVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPGGACLGKACGRKRK 692 >gi|126352608 elastin isoform e precursor [Homo sapiens] Length = 705 Score = 1347 bits (3487), Expect = 0.0 Identities = 687/729 (94%), Positives = 687/729 (94%), Gaps = 42/729 (5%) Query: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG 60 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG Sbjct: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG 60 Query: 61 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 120 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG Sbjct: 61 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 120 Query: 121 LGVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV 180 LGVSA GAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV Sbjct: 121 LGVSA-----GAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV 175 Query: 181 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV 240 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV Sbjct: 176 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV 235 Query: 241 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI 300 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI Sbjct: 236 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI 295 Query: 301 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP 360 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP Sbjct: 296 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP 355 Query: 361 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP 420 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP Sbjct: 356 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP 415 Query: 421 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVP 480 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKY GLVP Sbjct: 416 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKY-------------------GLVP 456 Query: 481 GVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVA 540 GVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVA Sbjct: 457 GVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVA 516 Query: 541 AKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKY 600 AKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKY Sbjct: 517 AKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKY 576 Query: 601 GAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL 660 GAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL Sbjct: 577 GAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL 636 Query: 661 GVPGVGGLGGIPPAAAAKAAKY------------------GVAARPGFGLSPIFPGGACL 702 GVPGVGGLGGIPPAAAAKAAKY GVAARPGFGLSPIFPGGACL Sbjct: 637 GVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGACL 696 Query: 703 GKACGRKRK 711 GKACGRKRK Sbjct: 697 GKACGRKRK 705 >gi|126352700 elastin isoform b precursor [Homo sapiens] Length = 677 Score = 1330 bits (3443), Expect = 0.0 Identities = 677/711 (95%), Positives = 677/711 (95%), Gaps = 34/711 (4%) Query: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG 60 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYP ALGPGG Sbjct: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYP----------ALGPGG 50 Query: 61 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 120 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG Sbjct: 51 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 110 Query: 121 LGVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV 180 LGVSA GAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV Sbjct: 111 LGVSA-----GAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV 165 Query: 181 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV 240 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV Sbjct: 166 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV 225 Query: 241 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI 300 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI Sbjct: 226 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI 285 Query: 301 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP 360 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP Sbjct: 286 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP 345 Query: 361 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP 420 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP Sbjct: 346 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP 405 Query: 421 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVP 480 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKY GLVP Sbjct: 406 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKY-------------------GLVP 446 Query: 481 GVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVA 540 GVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVA Sbjct: 447 GVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVA 506 Query: 541 AKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKY 600 AKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKY Sbjct: 507 AKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKY 566 Query: 601 GAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL 660 GAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL Sbjct: 567 GAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL 626 Query: 661 GVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPGGACLGKACGRKRK 711 GVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPGGACLGKACGRKRK Sbjct: 627 GVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPGGACLGKACGRKRK 677 >gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] Length = 1464 Score = 180 bits (457), Expect = 4e-45 Identities = 241/739 (32%), Positives = 271/739 (36%), Gaps = 116/739 (15%) Query: 23 PSRPG--GVPGAI-PGGVPGGVFYPGAG--LGALGG-GALGPGGKPLKPVPGGLAGAGLG 76 P PG G PG + P G+PG PGA GA G GA G G P P G G Sbjct: 289 PGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPG---- 344 Query: 77 AGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVVPQ 136 FPGA+ G A + ++ G+ G PG G +A P+ Sbjct: 345 ----------FPGAVGAKGEAGPQGP-RGSEGPQGVRGEPGPPGPAGAAGPA------GN 387 Query: 137 PGAGVKPGKVPGVGLPGVYPGGVLPGARFP----GVGVLPGVPTGAGVKPKAPGVGGAFA 192 PGA +PG G PG+ PGAR P G G PG P G +P APG G Sbjct: 388 PGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPG-PKGNSGEPGAPGSKGDTG 446 Query: 193 GIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTG 252 GP G P P G K G G P TG LP GP G G G G+P Sbjct: 447 AKGEPGPVGVQGPPGPAGEEGKR----GARGEPGPTG-LP---GPPGERGGPGSRGFPGA 498 Query: 253 TGV----GPQAAAAAAAKAAAKFGAGAAGV-----LPGVGG-AGVPGVPG---------- 292 GV GP + A K G AG LPG G G PG PG Sbjct: 499 DGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGP 558 Query: 293 ----------AIPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLVPGGPG-FGP-GVV 339 PG G AGV G P AA KA + G VPG PG GP G Sbjct: 559 AGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERG-----VPGPPGAVGPAGKD 613 Query: 340 GVPGA-GVPGVGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGG 398 G GA G PG P AG PG G+ P A K + G +G G Sbjct: 614 GEAGAQGPPGPAGPAGERGEQGPAGSPG--FQGLPGPAGPPGEAGKPGEQGVPGDLGAPG 671 Query: 399 IPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYG 458 P+ G GFPG GV G PG AG G G PG G G +P A + A + Sbjct: 672 -PSGARGERGFPGER-GVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGM 729 Query: 459 VGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGV----GLAPGVGVAPGVGV 514 G AA +PG G G +PG GL +G PG Sbjct: 730 PGERGAAG------------LPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIG-PPGPAG 776 Query: 515 APG----VGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGA-GIPGLGVGVGVPGLGV 569 APG G + GP G A + A GA G PG G G Sbjct: 777 APGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKG 836 Query: 570 GAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPA 629 AG PG AG PG GA AK A+ A PG G GA G VG PG AGP Sbjct: 837 DAGPPGPAGPAGPPGPIGNVGA-PGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPP 895 Query: 630 AAAAAAKAAAKAAQFGLVGAAGL-GGLG-------VGGLGVPGVGGLGGIP--PAAAAKA 679 A G G AG G +G G G PG G G P P A Sbjct: 896 GPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIA 955 Query: 680 AKYGVAARPGFGLSPIFPG 698 + GV PG FPG Sbjct: 956 GQRGVVGLPGQRGERGFPG 974 Score = 167 bits (423), Expect = 3e-41 Identities = 226/714 (31%), Positives = 253/714 (35%), Gaps = 85/714 (11%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAF 82 PS P G+PG P G PG + G GA GP G P P G G AG Sbjct: 183 PSGPRGLPG--PPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGR 240 Query: 83 PAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVVPQPGAGVK 142 P P A K G G+ G G A P+ P PG Sbjct: 241 PGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKG---DAGPAGPKGEPGSPGENGA 297 Query: 143 PGKVPGVGLPGVY--PGGVLP-GAR----FPGVGVLPGVPTGAGVKPKAPGVGGAFAGIP 195 PG++ GLPG PG P GAR G PG PTG P PG GA Sbjct: 298 PGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPG-PTGPAGPPGFPGAVGAKGEAG 356 Query: 196 GVGPFGGPQPGVPLGYPIKAPKLPGGY----GLPYTTGKLPYGYGPGGVAGAAGKAGYPT 251 GP G P G P P P G G P G+ P G G G AG G+P Sbjct: 357 PQGPRGSEGPQGVRGEP--GPPGPAGAAGPAGNPGADGQ-PGAKGANGAPGIAGAPGFPG 413 Query: 252 GTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAA 311 G P K +G G G G G PG + GV P A Sbjct: 414 ARG--PSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPV-------GVQGPPGPAG 464 Query: 312 AAAAAKAAKYGAAAGLVPGGPGF--GPGVVGVPGA-GVPGV-------GVPG-AGIPVVP 360 A GL PG PG GPG G PGA GV G G PG AG P Sbjct: 465 EEGKRGARGEPGPTGL-PGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSP 523 Query: 361 G-------AGIPGA----AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGF 409 G AG+PGA PG P+ A + G RPG P GA G Sbjct: 524 GEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDG-RPG------PPGPPGARGQ 576 Query: 410 PGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAA-AAAK 468 G +G G G AG PG G GV G PG + P + A G PA + Sbjct: 577 AGV-MGFPGPKGAAGEPGKAGERGVPGPPG-AVGPAGKDGEAGAQGPPGPAGPAGERGEQ 634 Query: 469 AAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGV-GVAPGIGPG 527 A + F +PG PG PG PG APG A G PG GV GP Sbjct: 635 GPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPA 694 Query: 528 GVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGA 587 G A + AK AG PG G PGL G+PG AG+PG Sbjct: 695 GPRGANGAPGNDGAKGD--------AGAPGAPGSQGAPGL---QGMPGERGAAGLPGPKG 743 Query: 588 VPGALA--AAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFG 645 G A + V G+ G +G G G PG +GP+ A A G Sbjct: 744 DRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRG 803 Query: 646 LVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPGG 699 G G G G G G G G P A AK G A PG P P G Sbjct: 804 EPGPPGPAGF-AGPPGADGQPGAKGEPGDAGAK----GDAGPPG----PAGPAG 848 Score = 165 bits (418), Expect = 1e-40 Identities = 224/678 (33%), Positives = 249/678 (36%), Gaps = 88/678 (12%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAG-----AGLGA 77 P P G PG G+PG PG P G P P P GL G G Sbjct: 122 PRGPAGPPGR--DGIPGQPGLPG------------PPGPPGPPGPPGLGGNFAPQLSYGY 167 Query: 78 GLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVVPQP 137 + ++ PG + P G A G G PG G ++ P P P Sbjct: 168 DEKSTGGISVPGPMGPSGPRGLPGP-PGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPP 226 Query: 138 GAGVKPGKVPGVGLPGVY-PGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPG 196 G G+ G PG P G PG LPG+ G G+ GA Sbjct: 227 GKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFS----GLDGAKGDAGP 282 Query: 197 VGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVA---GAAGKAGYPTGT 253 GP G +PG P AP G GLP G+ P GP G GA G AG P T Sbjct: 283 AGPKG--EPGSP--GENGAPGQMGPRGLPGERGR-PGAPGPAGARGNDGATGAAGPPGPT 337 Query: 254 GVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAA 313 GP AK AG G G GV G PG PG G AG PA A Sbjct: 338 --GPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGP-PGPAGAAG---PAGNPGAD 391 Query: 314 AAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPG----AGIPVVPGA-GIPGA- 367 A A G + G PGF PG G G PG G PG +G P PG+ G GA Sbjct: 392 GQPGAKGANGAPG-IAGAPGF-PGARGPSGPQGPG-GPPGPKGNSGEPGAPGSKGDTGAK 448 Query: 368 AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIP-----TYGVGAGGFPGFGVGVGGIPGV 422 PG V + A + K GAR G G+P G G+ GFPG GV G G Sbjct: 449 GEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPG-ADGVAGPKGP 507 Query: 423 AGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGV 482 AG G G G G PG P AK G+P A PG Sbjct: 508 AGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGP 567 Query: 483 GVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG-IGPGGV--AAAAKSAAKV 539 PG GV PG G PG GV PG +GP G A A+ Sbjct: 568 PGPPGARGQAGVMGFPG---PKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGP 624 Query: 540 AAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAK 599 A A R G AG PG G+PG AG PG AG PG VPG L Sbjct: 625 AGPAGERGEQG-PAGSPGF---QGLPG---PAGPPG---EAGKPGEQGVPGDL------- 667 Query: 600 YGAAVPGVLGGLGALGGVGIPG--GVVG-AGPAAAAAAAKAAAKAAQFGLVGAAGL-GGL 655 G G GA G G PG GV G GPA A A G GA G G Sbjct: 668 ------GAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQ 721 Query: 656 GVGGL-GVPGVGGLGGIP 672 G GL G+PG G G+P Sbjct: 722 GAPGLQGMPGERGAAGLP 739 Score = 159 bits (402), Expect = 8e-39 Identities = 232/765 (30%), Positives = 264/765 (34%), Gaps = 146/765 (19%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGA--GLGALGG-------GALGPGGKPLK------PVP 67 P PGG PG P G G PG+ GA G G GP G+ K P P Sbjct: 420 PQGPGGPPG--PKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGP 477 Query: 68 GGLAGAGL---GAGLGAFPAVTFPGALVPGGVADAAAAYKAA--KAGAGLGGVPGVGGL- 121 GL G G G FP G P G A + A K G G PG GL Sbjct: 478 TGLPGPPGERGGPGSRGFPGAD--GVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLP 535 Query: 122 GVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGAR-------FPGVGVLPGV 174 G PG+ P G PG G PG PG PGAR FPG G Sbjct: 536 GAKGLTGSPGSPGPDGKTG-PPGPAGQDGRPGP-PGP--PGARGQAGVMGFPGPKGAAGE 591 Query: 175 PTGAGVK--PKAPGVGGAFAGIPGVGPFGGPQPGVPLGY-----PIKAPK---LPGGYGL 224 P AG + P PG G G G P P P G P +P LPG G Sbjct: 592 PGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGP 651 Query: 225 PYTTGK-----LPYGYGPGGVAGAAGKAGYPTGTGV-------GPQAAAAAAAKAAAKFG 272 P GK +P G G +GA G+ G+P GV GP+ A A AK Sbjct: 652 PGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGD 711 Query: 273 AGAAGVLPGVGGAGVPGVPG-----AIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGL 327 AGA G G G+ G+PG +PG G G P A + K G + Sbjct: 712 AGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPG--KDGVRGLTGPI 769 Query: 328 VPGGPGFGPGVVGVPGA----------GVPG----VGVPG-AGIPVVPGA-------GIP 365 P GP PG G G G PG G PG AG PGA G P Sbjct: 770 GPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEP 829 Query: 366 G-------AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGG 418 G A PG P GA+ G G P GA GFPG G G Sbjct: 830 GDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPP----GATGFPG-AAGRVG 884 Query: 419 IPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGL 478 PG +G G G PG G G G P + A + + G P A + + A Sbjct: 885 PPGPSGNAGPPGPPGPAGKEG-GKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGAD--- 940 Query: 479 VPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI-GPGGVAAAAKSAA 537 G APG G+ GV PG G PG PG GP G + Sbjct: 941 --GPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGER---- 994 Query: 538 KVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKA 597 G PG +G PGL AG PG G PG PG + Sbjct: 995 ----------------GPPG---PMGPPGL---AGPPGESGREGAPGAEGSPGR-DGSPG 1031 Query: 598 AKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL-- 655 AK G G GA G G PG V AG + A A G VGA G G Sbjct: 1032 AKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQG 1091 Query: 656 ---------GVGGLGVPGVGGLGGI--PPAAAAKAAKYGVAARPG 689 G G+ G G G+ PP + G + G Sbjct: 1092 PRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASG 1136 Score = 145 bits (367), Expect = 1e-34 Identities = 216/716 (30%), Positives = 242/716 (33%), Gaps = 141/716 (19%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGA-GLGALGG--------GALGPGGKPLKPVPGGLAGA 73 P+ P G PG G PG PGA GL G G GP G+ +P P G GA Sbjct: 516 PAGPKGSPGE--AGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGA 573 Query: 74 GLGAGLGAFP----AVTFPGAL----VPGGVADAAAAYKAAKAGAGLGGVPGVGG----- 120 AG+ FP A PG VPG A K +AGA G PG G Sbjct: 574 RGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQ--GPPGPAGPAGER 631 Query: 121 --LGVSAAPSVPGAVVPQ--PGAGVKPGK--VPG-VGLPGVYPGGVLPGARFPGVGVLPG 173 G + +P G P PG KPG+ VPG +G PG P G FPG + G Sbjct: 632 GEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPG--PSGARGERGFPGERGVQG 689 Query: 174 VPTGAGVK-----------------PKAPGVGGA-----------FAGIPG--------- 196 P AG + P APG GA AG+PG Sbjct: 690 PPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAG 749 Query: 197 ----------------VGPFGGPQP-GVPLGYPIKAPKLPGG----YGLPYTTGKLPYGY 235 GP G P P G P P P G G P G+ P Sbjct: 750 PKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGE-PGPP 808 Query: 236 GPGGVAGAAGKAGYPTGTG----------VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGA 285 GP G AG G G P G GP A A GA G G A Sbjct: 809 GPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSA 868 Query: 286 GVPGVPGAIPGIGGIAGVGTPAA-AAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA 344 G PG G PG G G P+ A A K G GP PG VG PG Sbjct: 869 GPPGATG-FPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGP 927 Query: 345 GVPGVGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGV 404 P AG PGA P A PG P+ A G R G G+P Sbjct: 928 PGP------AGEKGSPGADGP-AGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLP---- 976 Query: 405 GAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAA 464 G G PG G G G G PG G PG+ G PG + A A+ + G+P A Sbjct: 977 GPSGEPG-KQGPSGASGERGPPGPMGPPGLAGPPG---ESGREGAPGAEGSPGRDGSPGA 1032 Query: 465 AAAKAAAKAAQFGLVPGVGVAPG-VGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG 523 + A PG APG VG A G G A G A VG G A Sbjct: 1033 KGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPA---GPAGPVGPVGARGPAGP 1089 Query: 524 IGPGGVAAAAKSAAKVAAKAQLRAAAGLGA-----GIPGLGVGVGVPGLGVGAGVPGLGV 578 GP G K R +GL G PG G G G PG Sbjct: 1090 QGPRGDKGETGEQGDRGIKGH-RGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAG 1148 Query: 579 GAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAA 634 G G +PG + PG G G G VG PG GP +A Sbjct: 1149 APGKDGLNGLPGPIGP----------PGPRGRTGDAGPVGPPGPPGPPGPPGPPSA 1194 Score = 110 bits (274), Expect = 6e-24 Identities = 167/552 (30%), Positives = 193/552 (34%), Gaps = 84/552 (15%) Query: 161 PGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPG 220 PGA P P P G+ P G GP G P P G +PG Sbjct: 82 PGAEVPEGECCPVCPDGSE-SPTDQETTGVEGPKGDTGPRGPRGPAGPPG----RDGIPG 136 Query: 221 GYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLP 280 GLP GP G G G G G PQ + K+ Sbjct: 137 QPGLP----------GPPGPPGPPGPPGL--GGNFAPQLSYGYDEKST------------ 172 Query: 281 GVGGAGVPGVPGAIPGIGGIAG-VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVV 339 GG VPG P G G+ G G P + + GA+ + P GP PG Sbjct: 173 --GGISVPG-PMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKN 229 Query: 340 GVPG-AGVPG----VGVPG-AGIPVVPG-AGIPGAAVPGVVSPEAAAKAAAKAAKYGARP 392 G G AG PG G PG G +PG AG+PG S AK A A P Sbjct: 230 GDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEP 289 Query: 393 G-VGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAA 451 G G G P +G G PG G G PG AG G G G G PG Sbjct: 290 GSPGENGAPGQ-MGPRGLPG-ERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPG 347 Query: 452 AKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPG 511 A AK G ++ PG A G PG PG A G APG Sbjct: 348 AVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPG---AKGANGAPG 404 Query: 512 VGVAPGVGVAPG----IGPGGVAAAAKSAAKVAAKAQLRAAAGLGA-GIPGLGVGVGVPG 566 + APG A G GPGG ++ + A + GA G PG VGV G Sbjct: 405 IAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPG---SKGDTGAKGEPG---PVGVQG 458 Query: 567 LGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALG-----GVGIPG 621 AG G G PG +PG PG GG G+ G GV P Sbjct: 459 PPGPAGEEGKRGARGEPGPTGLPGP-------------PGERGGPGSRGFPGADGVAGPK 505 Query: 622 GVVG----AGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAA 677 G G GPA + A + + GL GA GL G G PG G G PP A Sbjct: 506 GPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGL----TGSPGSPGPDGKTG-PPGPAG 560 Query: 678 KAAKYGVAARPG 689 + + G PG Sbjct: 561 QDGRPGPPGPPG 572 Score = 109 bits (273), Expect = 8e-24 Identities = 158/456 (34%), Positives = 172/456 (37%), Gaps = 68/456 (14%) Query: 26 PGGVPGAIPGGVPG--GVFYPGAGLGALGG-GALGPGGKPLKPVPGGLAGAGLGAGLGAF 82 P G PG P G PG G P G G GA G G+P P P G AG G Sbjct: 768 PIGPPG--PAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQ--- 822 Query: 83 PAVTFPGALVPGGVADAAAAYKAAKAG-AGLGGVPG-VGGLGVSAAPSVPGAVVPQPGAG 140 PGA G DA A A G AG G PG +G +G A G+ P PGA Sbjct: 823 -----PGA--KGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGP-PGAT 874 Query: 141 VKPGKVPGVGLPGVYPGGVLPG-------------------ARFPGVGVLPGVPTGAGVK 181 PG VG PG PG A PG PG P AG K Sbjct: 875 GFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEK 934 Query: 182 PKAPGVGGAFAGIPGV-GPFG-GPQPGVPLGYPIKA-----PKLPGGYGLPYTTGKLPYG 234 +PG G AG PG GP G Q GV +G P + P LPG G P G P G Sbjct: 935 G-SPGADGP-AGAPGTPGPQGIAGQRGV-VGLPGQRGERGFPGLPGPSGEPGKQG--PSG 989 Query: 235 Y----GPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGV 290 GP G G G AG P +G + A A GA G G AG PG Sbjct: 990 ASGERGPPGPMGPPGLAGPPGESG--REGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGA 1047 Query: 291 PGA--IPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AGV 346 PGA PG G AG G A A GA P GP G G G G+ Sbjct: 1048 PGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGI 1107 Query: 347 PGV-GVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVG 405 G G G P P G PG P S A + +A GA G+ G+P G Sbjct: 1108 KGHRGFSGLQGPPGP-PGSPGEQGPSGASGPAGPRGPPGSA--GAPGKDGLNGLP----G 1160 Query: 406 AGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVG 441 G PG G G G G PG G PG G P G Sbjct: 1161 PIGPPG-PRGRTGDAGPVGPPGPPGPPGPPGPPSAG 1195 Score = 84.0 bits (206), Expect = 5e-16 Identities = 122/376 (32%), Positives = 139/376 (36%), Gaps = 44/376 (11%) Query: 23 PSRPGGVPGAI-----PG--------GVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGG 69 P+ P G PG I PG G PG +PGA G +G GP G P P G Sbjct: 843 PAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAA-GRVGPP--GPSGNAGPPGPPG 899 Query: 70 LAGAGLGAG-LGAFPAVTFPGALVPGGVADAAA--AYKAAKAGAGLGGVPGVGGL-GVSA 125 AG G G G PG + P G A A AG G PG G+ G Sbjct: 900 PAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRG 959 Query: 126 APSVPGAVVPQPGAGVKPGKVPGVGLPGVY-PGGVLPGARFPGVGVLPGV--PTGAGVKP 182 +PG Q G PG G PG P G PG PG+ P G + Sbjct: 960 VVGLPG----QRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGRE 1015 Query: 183 KAPGVGGAFA--GIPGV-GPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGG 239 APG G+ G PG G G P P G P AP PG G +G G G Sbjct: 1016 GAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAP-GAPGAPGPVGPAGKSGDR----GETG 1070 Query: 240 VAGAAGKAGYPTGTG-VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIG 298 AG AG G G GPQ + + G G G G PG PG+ PG Sbjct: 1071 PAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGS-PGEQ 1129 Query: 299 GIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPG----A 354 G +G PA +A A GL GP PG G G P VG PG Sbjct: 1130 GPSGASGPAGPRGPPGSAGAPGKDGLNGL--PGPIGPPGPRGRTGDAGP-VGPPGPPGPP 1186 Query: 355 GIPVVPGAGIPGAAVP 370 G P P AG + +P Sbjct: 1187 GPPGPPSAGFDFSFLP 1202 Score = 74.7 bits (182), Expect = 3e-13 Identities = 105/355 (29%), Positives = 121/355 (34%), Gaps = 39/355 (10%) Query: 360 PGAGIP-GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGG 418 PGA +P G P V P+ + + P G P G G PG G Sbjct: 82 PGAEVPEGECCP--VCPDGSESPTDQETTGVEGPKGDTG--PRGPRGPAGPPGRD----G 133 Query: 419 IPGVAGVPGVGGVPGVGGVPGVG--ISP-------EAQAAAAAKAAKYGVGTPAAAAAKA 469 IPG G+PG G PG G PG+G +P E + G P Sbjct: 134 IPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPP 193 Query: 470 AAKAAQ-FGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPG-VGVAPGIGPG 527 A Q F PG PG G PG PG G PG G GP Sbjct: 194 GAPGPQGFQGPPGEPGEPGASGPMGPRGPPG---PPGKNGDDGEAGKPGRPGERGPPGPQ 250 Query: 528 GVAAAAKSAAKVAAKAQLRAAAGL--GAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGF 585 G +A K R +GL G G G PG G PG G+PG Sbjct: 251 GARGLPGTAGLPGMKGH-RGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGE 309 Query: 586 GAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFG 645 PGA A G G GA G G PG AGP A A +A G Sbjct: 310 RGRPGAPGPA----------GARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQG 359 Query: 646 LVGAAGLGGLGVGGLGVPGVGGLGGIP--PAAAAKAAKYGVAARPGFGLSPIFPG 698 G+ G G+ G G PG G G P A + G PG +P FPG Sbjct: 360 PRGSEGPQGVR-GEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPG 413 >gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] Length = 1466 Score = 176 bits (446), Expect = 7e-44 Identities = 222/706 (31%), Positives = 257/706 (36%), Gaps = 100/706 (14%) Query: 26 PGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAV 85 P G PG P G PG +PG+ G GP G+P + P G G Sbjct: 175 PAGPPG--PPGPPGTSGHPGSPGSP---GYQGPPGEPGQAGPSGPPGP------------ 217 Query: 86 TFPGALVPGGVA--DAAAAYKAAKAGAGLGGVPGVGG-LGVSAAPSVPGAVVPQPGAGVK 142 PGA+ P G A D + GL G PG+ G G+ P + G G + Sbjct: 218 --PGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKG----HRGFDGR 271 Query: 143 PGKVPGVGLPGVYPGGVLPGAR-FPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFG 201 G+ G PG+ LPG PG G P G +P PG GA G G Sbjct: 272 NGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERG-RPGLPGAAGARGNDGARGSDG 330 Query: 202 GPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV-GPQAA 260 P P P PG G P + G G G AG+ G G P G GPQ Sbjct: 331 QPGPPGP----------PGTAGFPGSPG----AKGEVGPAGSPGSNGAPGQRGEPGPQGH 376 Query: 261 AAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAK 320 A A G+ G +G AG+PG PG + G G A A + K Sbjct: 377 AGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGK 436 Query: 321 YGAAAGLVPGGPGFGPGVVGVPGA----------GVPGV-GVPGA----GIPVVPGA--- 362 GA P G G+ GVPGA G PG G+PGA G P G Sbjct: 437 NGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGP 496 Query: 363 -GIPGAAVP----GVVSPEAAAKAAAKAAKYGARPGVGVGGIP--TYGVGAGGFPG--FG 413 GIPG P G P AA + + G G G+ G+P G G+ G PG Sbjct: 497 NGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGS 556 Query: 414 VGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKA 473 G G PG G G G PGV G PG + A + G G P K Sbjct: 557 QGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPG-PQGPPGKNGETG 615 Query: 474 AQFGLVP-GVGVAPGVGVAP---GVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGV 529 Q P G G G P G+ PG G PG PG G APG PGG Sbjct: 616 PQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPG-APGGK 674 Query: 530 AAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVG---AGVPGLGVGAGVPGFG 586 A R GL AG PGL G G PG G AG PG AG PG Sbjct: 675 GDAGAPGE--------RGPPGL-AGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQ 725 Query: 587 AVPGALAAAKAAKYGAAVPGVLGGLGALGGV---GIPGGVVGAGPAAAAAAAKAAAKAAQ 643 +PG + G PG G G GG G+PG GP A + Sbjct: 726 GMPG-------ERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGD 778 Query: 644 FGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPG 689 G GA GL G+ G G PG G G PP A G PG Sbjct: 779 KGEGGAPGLPGI-AGPRGSPGERGETG-PPGPAGFPGAPGQNGEPG 822 Score = 164 bits (414), Expect = 3e-40 Identities = 237/740 (32%), Positives = 265/740 (35%), Gaps = 123/740 (16%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAF 82 PS P G PGAI P AG G PG + L P P G+ G AG+ F Sbjct: 211 PSGPPGPPGAIGPSGP-------AGKDGESGRPGRPGERGL-PGPPGIKGP---AGIPGF 259 Query: 83 PAVT----FPGALVPGGVADAAAAYKAAKAGAGLGGVPGV----GGLGVSAAPSVPGAVV 134 P + F G G A K G G PG G G P +PGA Sbjct: 260 PGMKGHRGFDGRNGEKG-ETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAG 318 Query: 135 P-----------QPGAGVKPGKVPGVGLPG----VYPGGVLPGARFPGVGVLPGVPTGAG 179 QPG PG G PG V P G PG PG AG Sbjct: 319 ARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAG 378 Query: 180 VK--PKAPGVGGA--------FAGIPGV-GPFGGPQPGVPLGYPIKAPKLPGGYGLPYTT 228 + P PG+ G+ AGIPG G G P P G AP L GG G P Sbjct: 379 AQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAG-ANGAPGLRGGAGEPGKN 437 Query: 229 GKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVP 288 G G G G G+AG P G A K + GA G+ G G P Sbjct: 438 G----AKGEPGPRGERGEAGIP-----GVPGAKGEDGKDGSPGEPGANGLPGAAGERGAP 488 Query: 289 GV-----PGAIPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFG--PGVVG 340 G P IPG G AG G P A AA + + G VPGGPG PG G Sbjct: 489 GFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDG-----VPGGPGMRGMPGSPG 543 Query: 341 VPGA-GVPGVGVPG----AGIPVVPGAGIPGA--AVPGVVSPEAAAKAAAKAAKYGARPG 393 PG+ G P G PG +G P PG P V G P+ A K + G G Sbjct: 544 GPGSDGKP--GPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGG 601 Query: 394 VGVGGIPTYG--VGAGGFPGFGVGVGGIPGVAGVP---GVGGVPGVGGVPGVGISPEAQA 448 G G P G G PG G GG G G P G+ G+PG GG PG P Sbjct: 602 PGPQGPPGKNGETGPQGPPG-PTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKP---- 656 Query: 449 AAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGV-GVAPGVGVAPGVGLA---- 503 K G P A K A A PG+ APG+ G A G G G A Sbjct: 657 --GEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPG 714 Query: 504 -PGVGVAPGVGVAPGV-GVAPGIGPGGVAA--AAKSAAKVAAKAQLRAAAG-LG----AG 554 PG PG+ PG G GP G A V K R G +G AG Sbjct: 715 PPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAG 774 Query: 555 IP---GLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGL 611 P G G G+PG+ G PG G PG PGA PG G Sbjct: 775 QPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGA-------------PGQNGEP 821 Query: 612 GALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL--GVGGLGVPGVGGLG 669 G G G PG GP A + A G G G G G G G PG GL Sbjct: 822 GGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLP 881 Query: 670 GIPPAAAAKAAKYGVAARPG 689 G PP + G + PG Sbjct: 882 G-PPGSNGNPGPPGPSGSPG 900 Score = 159 bits (402), Expect = 8e-39 Identities = 240/815 (29%), Positives = 272/815 (33%), Gaps = 153/815 (18%) Query: 17 LLSILHPSRPGGVPGAIPGGVPGGVFYPG----------------AGLGALGG--GALGP 58 L+ P P G GA G+ GG PG AG+ + G G G Sbjct: 409 LMGARGPPGPAGANGA--PGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGK 466 Query: 59 GGKPLKPVPGGLAGAGLGAGLGAFPAVT----FPGALVPGGV--ADAAAAYKAAKAGAGL 112 G P +P GL GA G F PG P G A A + A G Sbjct: 467 DGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGR 526 Query: 113 GGVPGVGGLGVSAAPSVPGAVVPQPGAGVKPGKVPGV----GLPGVYPGGVLPGARFPGV 168 GVPG G G+ P PG PG+ KPG PG G PG PG P + PGV Sbjct: 527 DGVPG--GPGMRGMPGSPGG----PGSDGKPGP-PGSQGESGRPGP-PGPSGPRGQ-PGV 577 Query: 169 GVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFG--------GPQ-PGVPLGY-------- 211 PG G APG G G G GP G GPQ P P G Sbjct: 578 MGFPGPKGNDG----APGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTG 633 Query: 212 ---PIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV-GPQAAAAAAAKA 267 P LPG G P GK P GP G AGA G G G G + A Sbjct: 634 PPGPQGLQGLPGTGGPPGENGK-PGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAP 692 Query: 268 AAKFGAGAAGVLPGVGGAGVPGVPGAI--PGIGGIAGV-------------GTPAAAAAA 312 + GAG G G G AG PG PGA PG+ G+ G G P A Sbjct: 693 GLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGAD 752 Query: 313 AAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPGV-------------GVPG-AGIP 357 K G + P GP PG G GA G+PG+ G PG AG P Sbjct: 753 GVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFP 812 Query: 358 VVPGA----------GIPG----AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYG 403 PG G PG PGV P + A G + G G G Sbjct: 813 GAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPG----G 868 Query: 404 VGAGGFPGF--------------------GVGVGGIPGVAGVPGVGGVPGVGGVPGVGIS 443 GA GFPG G G PG AG G G PGV G G Sbjct: 869 PGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQ 928 Query: 444 PEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLA 503 P + + A+ G A A A +PG +PG G PG Sbjct: 929 PGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGL 988 Query: 504 PGVGVAPGVGVAPGVGVAPG-------IGPGGVAAAAKSAAKVAAKAQLRAAAGLGA-GI 555 G PG PG+ G G G+ S + + + GA G Sbjct: 989 SGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGH 1048 Query: 556 PGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALA--AAKAAKYGAAVPGVLGGLGA 613 PG VG G G G AG PG GA + K G G G Sbjct: 1049 PGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGH 1108 Query: 614 LGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPP 673 G G PG GPA A + A G VG +G G G G PG G PP Sbjct: 1109 RGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKD-GTSGHPGPIG----PP 1163 Query: 674 AAAAKAAKYGVAARPGFGLSPIFPG-----GACLG 703 + G PG P PG G C G Sbjct: 1164 GPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCG 1198 Score = 159 bits (401), Expect = 1e-38 Identities = 209/689 (30%), Positives = 242/689 (35%), Gaps = 118/689 (17%) Query: 26 PGGVPGAI-PGGVPGGVFYPGA-GLGALGG--GALGPGGKPLKPVPGGLAGAGLGAGLGA 81 P G PG PGG G PG GL L G G G GKP +P P G AGA Sbjct: 616 PQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGA-------- 667 Query: 82 FPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGV----------GGLGVSAAPSVPG 131 PGA PGG DA A + GL G PG+ GG G + P PG Sbjct: 668 ------PGA--PGGKGDAGAP--GERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPG 717 Query: 132 AVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGV-----PTGAGVKPKAPG 186 A PG PG+ G+G PG PG PG +PG PTG + P P Sbjct: 718 AA-GTPGLQGMPGERGGLGSPGPKGDKGEPGG--PGADGVPGKDGPRGPTGP-IGPPGP- 772 Query: 187 VGGAFAGIPGVGPFGGPQPGVP-LGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAG 245 AG PG GG PG+P + P +P G G P GP G GA G Sbjct: 773 -----AGQPGDKGEGGA-PGLPGIAGPRGSPGERGETGPP----------GPAGFPGAPG 816 Query: 246 KAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGT 305 + G P G G K G GV GG+G G PG G G Sbjct: 817 QNGEPGGKG--------ERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGG 868 Query: 306 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIP 365 P AA A G+ P GP PG G PG G PG+ Sbjct: 869 PGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPA-GNTGAPGS----------- 916 Query: 366 GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGV 425 PGV P+ A + GA+ G G P G G G G G+ G G+ Sbjct: 917 ----PGVSGPKGDAGQPGEKGSPGAQ---GPPGAP----GPLGIAGI-TGARGLAGPPGM 964 Query: 426 PGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVA 485 PG G PG GV G P A + + G P A PG Sbjct: 965 PGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGE---------PGRDGN 1015 Query: 486 PGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG-IGPGGVAAAAKSAAKVAAKAQ 544 PG PG +PG G +PG APG PG +GP G + + + A A Sbjct: 1016 PGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAG-KSGDRGESGPAGPAG 1074 Query: 545 LRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAV 604 AG G PG G G G G+ G PG PG+ Sbjct: 1075 APGPAG-SRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGS------------- 1120 Query: 605 PGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL--GVGGLGV 662 PG G GA+G G G GP+ + G G G G G G Sbjct: 1121 PGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGH 1180 Query: 663 PGVGGLGGIPPAAAAKAAKYGVAARPGFG 691 PG G G P A G AA G G Sbjct: 1181 PGQPGPPGPPGAPGPCCGGVGAAAIAGIG 1209 Score = 125 bits (315), Expect = 1e-28 Identities = 160/531 (30%), Positives = 187/531 (35%), Gaps = 95/531 (17%) Query: 203 PQPGVPLG-------YPIKAPKLP-------GGYGLPYTTGKLPYGYGPGGVAGAAGKAG 248 P P +P G P AP P G G P G +P G G+ G G G Sbjct: 75 PNPEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPG-IPGRNGDPGIPGQPGSPG 133 Query: 249 YPTGTGV------GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAG 302 P G+ GPQ + K G G+ G AG PG PG PG G Sbjct: 134 SPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGP-PGTSG--- 189 Query: 303 VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGA 362 PG PG PG G PG PG P + Sbjct: 190 -------------------------HPGSPG-SPGYQGPPGE--PGQAGP---------S 212 Query: 363 GIPGAAVPGVVSPEAAAKAAAKAAKYGARPGV-GVGGIPTYGVGAG--GFPGF--GVGVG 417 G PG PG + P A ++ + G RPG G+ G P AG GFPG G Sbjct: 213 GPPGP--PGAIGPSGPAGKDGESGRPG-RPGERGLPGPPGIKGPAGIPGFPGMKGHRGFD 269 Query: 418 GIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFG 477 G G G G G+ G G+PG +P A + G P AA A+ A Sbjct: 270 GRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSD 329 Query: 478 LVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAA 537 PG PG PG +PG G +PG APG P GP G A A Sbjct: 330 GQPGPPGPPGTAGFPG---SPGAKGEVGPAGSPGSNGAPGQRGEP--GPQGHAGAQGPPG 384 Query: 538 KVAAKAQLRAAAGLG----AGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALA 593 +G G PGL G PG G PGL GAG PG G Sbjct: 385 PPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGE-P 443 Query: 594 AAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLG 653 + + A +PGV G G G G P G GA AA + A G G AG Sbjct: 444 GPRGERGEAGIPGVPGAKGEDGKDGSP-GEPGANGLPGAAGERGAP-----GFRGPAGPN 497 Query: 654 GL-----GVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPGG 699 G+ G G PG G P AA + + GV PG P PGG Sbjct: 498 GIPGEKGPAGERGAPGPAG----PRGAAGEPGRDGVPGGPGMRGMPGSPGG 544 Score = 104 bits (259), Expect = 3e-22 Identities = 153/474 (32%), Positives = 167/474 (35%), Gaps = 70/474 (14%) Query: 23 PSRPGGVPGAI-PGGVPG--GVFYPGAGLGALGG-GALGPGGKPLKP----VPGGLA--G 72 P P G PG GG PG G+ P G G G GP G P P PGG G Sbjct: 769 PPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERG 828 Query: 73 AGLGAGLGAFPAVTFPGALVPGGVADAAA-------AYKAAKAGAGLGGVPGVGGL---- 121 A G G P V P PGG A + + G G G PG GL Sbjct: 829 APGEKGEGGPPGVAGP----PGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPP 884 Query: 122 GVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPG--GVLPGARFPGVGVLPGV--PTG 177 G + P PG PG PG G PG PG G A PG PG P G Sbjct: 885 GSNGNPGPPGPS-GSPGKDGPPGPAGNTGAPGS-PGVSGPKGDAGQPGEKGSPGAQGPPG 942 Query: 178 AGVKPKAPGVGGA--FAGIPGV-GPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYG 234 A G+ GA AG PG+ GP G P P G K PG GL G Sbjct: 943 APGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGK----PGANGLSGERGPP--- 995 Query: 235 YGPGGVAGAAGKAGYPTGTG-VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGA 293 GP G+ G AG AG P G G K G G G G PG PG Sbjct: 996 -GPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGP 1054 Query: 294 IPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPGV-GV 351 + G G A A A A GA P GP G G GA G+ G G Sbjct: 1055 VGPAGKSGDRGESGPAGPAGAPGPAGSRGAPG---PQGPRGDKGETGERGAAGIKGHRGF 1111 Query: 352 PG-AGIPVVPG-AGIPGA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIP-------- 400 PG G P PG AG GA PG P + K G G G P Sbjct: 1112 PGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGE 1171 Query: 401 TYGVGAGGFPGF----------GVGVGGIPGVAGVPGVGGVPGVGGVPGVGISP 444 G+ G PG G GG+ G A + G+GG G P G P Sbjct: 1172 RGSEGSPGHPGQPGPPGPPGAPGPCCGGV-GAAAIAGIGGEKAGGFAPYYGDEP 1224 >gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] Length = 1669 Score = 176 bits (445), Expect = 9e-44 Identities = 240/810 (29%), Positives = 304/810 (37%), Gaps = 174/810 (21%) Query: 3 GLTAAAPRPGVLLLLLSILHPSRPG--GVPGAI----PGGVPGGVFYPGA---------- 46 G+T A PG HP PG G PG++ G PGGV +PG+ Sbjct: 553 GMTGRAGSPG------RDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPP 606 Query: 47 GLGALGG----------------GALGPGGKPLK--PVPGGLAGAGLGAGLGAFPAVT-- 86 G G G G GP G+P K P+PG GL G FP Sbjct: 607 GYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPG-FPGPQGD 665 Query: 87 --FPGALVPGGVADAAAAYKAAKAGAGLGGVPGV-------GGLGVSAAPSVPG--AVVP 135 FPG PG + G G G PG G +G P PG + Sbjct: 666 RGFPGT--PGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPG 723 Query: 136 QPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFA--G 193 PG + G+ PGVGLPG+ LPG PG+ PG GV P PG GA G Sbjct: 724 NPGVQGQKGE-PGVGLPGLKG---LPG--LPGIPGTPGEKGSIGV-PGVPGEHGAIGPPG 776 Query: 194 IPGV----GPFGGP----QPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAG 245 + G+ GP G P PGVP P A PGG G P +G P G+ G G Sbjct: 777 LQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSG-------PPGIKGEKG 829 Query: 246 KAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGA-GVPGVPGAIPGIGGIAGVG 304 G+P GP+ A +G G LPG GA G+PG PG+ +G + G Sbjct: 830 FPGFPGLDMPGPKGDKGAQGLPGITGQSGLPG-LPGQQGAPGIPGFPGSKGEMGVMGTPG 888 Query: 305 TPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AGVPGVGVPGAGIPVVPGA- 362 P + A + G GP PG+ G G G+P G PG+ V G+ Sbjct: 889 QPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLP--GKPGSMDKVDMGSM 946 Query: 363 ----------------------GIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIP 400 G PG PGV + A + + G + G+ G P Sbjct: 947 KGQKGDQGEKGQIGPIGEKGSRGDPG--TPGVPGKDG---QAGQPGQPGPKGDPGISGTP 1001 Query: 401 TYGVGAGGFPG-----FGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAA 455 GA G PG G+G+ G PG GVPG+ G G G+PG + +A Sbjct: 1002 ----GAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPG----DKGAKGEKGQAG 1053 Query: 456 KYGVGTPAAAAAKAAAKAAQFGLVPG-------VGVAPGVGVAPGVGVAPG-VGL--APG 505 G+G P K A F PG +G+ PG+ +PG+ +PG VG +PG Sbjct: 1054 PPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGI-PGMPGSPGLKGSPGSVGYPGSPG 1112 Query: 506 VGVAPGVGVAPGVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGV 564 + G PG+ PG+ G G+ K G PG G+ Sbjct: 1113 LPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQK-----------GEPG---SDGI 1158 Query: 565 PGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVV 624 PG G PGL G G PGF PGA K +K PG+ G G G G G + Sbjct: 1159 PGSAGEKGEPGL-PGRGFPGF---PGA-KGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMG 1213 Query: 625 GAGPAAAAAAAKAAAKAAQ-----FGLVGAAGLGGLGVGGLGVPGVGGLGGI-------- 671 GP + A + G G GL GL G +G PG+ G+ G+ Sbjct: 1214 PPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGL-PGPMGPPGLPGIDGVKGDKGNPG 1272 Query: 672 ---PPAAAAKAAKYGVAARPGFGLSPIFPG 698 P G PG G SP G Sbjct: 1273 WPGAPGVPGPKGDPGFQGMPGIGGSPGITG 1302 Score = 172 bits (437), Expect = 7e-43 Identities = 228/733 (31%), Positives = 290/733 (39%), Gaps = 102/733 (13%) Query: 23 PSRPG--GVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLG 80 P RPG G+PG GV G PG GL PG K L +PG G +G Sbjct: 713 PGRPGFNGLPGN--PGVQGQKGEPGVGL---------PGLKGLPGLPGIPGTPGEKGSIG 761 Query: 81 AFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVVPQPGAG 140 GA+ P G+ G G PGV G+G A PG P PG Sbjct: 762 VPGVPGEHGAIGPPGL-QGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGP-PGLS 819 Query: 141 VKPGKVPGVGLPGVYPGGVLPGARFP-GVGVLPGVPTGAGVKPKAPGVGGAFAGIPG--- 196 PG G PG +PG +PG + G LPG+ TG P PG GA GIPG Sbjct: 820 GPPGIKGEKGFPG-FPGLDMPGPKGDKGAQGLPGI-TGQSGLPGLPGQQGA-PGIPGFPG 876 Query: 197 ----VGPFGGP-QPGVPLGYPIKAPKLPG---GYGLPYTTGKLPYGYGPGGVAGAAGKAG 248 +G G P QPG P P+ AP LPG +G P ++G G G+ G G G Sbjct: 877 SKGEMGVMGTPGQPGSP--GPVGAPGLPGEKGDHGFPGSSGPR----GDPGLKGDKGDVG 930 Query: 249 YPTGTGVGPQAAAAAAAKAAAKFGA-GAAGVLPGVGGAGVPGVPGAIPGIGGIAGV---- 303 P G + + G G G + G G PG PG +PG G AG Sbjct: 931 LPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPG-VPGKDGQAGQPGQP 989 Query: 304 ---GTPAAAAAAAAAAKAAKYGAAAGL-VPGGPGFGPGVVGVPGA-GVPGV-GVPGA--- 354 G P + A G+ G+ +PG PG GV G+PG G PG+ G GA Sbjct: 990 GPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPG-EKGVPGIPGPQGSPGLPGDKGAKGE 1048 Query: 355 -GIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTY-----GVGAGG 408 G PG GIPG + G + A + G + +G+ G+P G+ G Sbjct: 1049 KGQAGPPGIGIPG--LRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVG 1106 Query: 409 FPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAK 468 +PG G+ G G G+PG+ G+PGV G G+ +P A K G P +A K Sbjct: 1107 YPG-SPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEK 1165 Query: 469 AAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPG----VGVAPGVGVAPGI 524 G PG A G + G PG+ +PG+ + G +G PG PG+ Sbjct: 1166 GEPGLPGRGF-PGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMG-PPGPQGQPGL 1223 Query: 525 --GPGGVAAAAKSAAKVAAKAQLRAAAG-LGA-GIPGLGVGVGVPGLGVGAGVPGLGVGA 580 PG K + L G +G G+PG+ G G G PG+ Sbjct: 1224 PGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPK 1283 Query: 581 GVPGFGAVPG-----ALAAAKAAKYGAAVPGVLG--GLGALGGV-------GIPGGVVGA 626 G PGF +PG + +K VPG G GL L G+ G+PG Sbjct: 1284 GDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLP 1343 Query: 627 GPAAAAAAAKAAAKAAQFGLVGAAGLGGL-GVGGL----GVPGVGGLGGIPPAAAAKAAK 681 GP + GL G G GL G+ GL G GV GL GIP Sbjct: 1344 GPPGPPGPYDII--KGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIP--------- 1392 Query: 682 YGVAARPGFGLSP 694 G PGF +P Sbjct: 1393 -GPPGIPGFDGAP 1404 Score = 155 bits (393), Expect = 9e-38 Identities = 215/696 (30%), Positives = 260/696 (37%), Gaps = 143/696 (20%) Query: 28 GVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTF 87 G PG P G+PG V PG G G G G P P GL+G G FP F Sbjct: 782 GEPG--PPGLPGSVGSPGVP----GIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPG--F 833 Query: 88 PGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGL-GVSAAPSVPG--------AVVPQPG 138 PG +PG D K A+ G+ G G+ GL G AP +PG V+ PG Sbjct: 834 PGLDMPGPKGD-----KGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPG 888 Query: 139 AGVKPGKVPGVGLPGVYPGGVLPGARFP-GVGVLPGVPTGAGVKPKAPGVG----GAFAG 193 PG V GLPG PG+ P G L G G+ K + G+ G Sbjct: 889 QPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKG 948 Query: 194 IPG-------VGPFGGP----QPGVPLGYPIK-----APKLPGGYGLPYTTGK--LPYGY 235 G +GP G PG P G P K P PG G P +G P Sbjct: 949 QKGDQGEKGQIGPIGEKGSRGDPGTP-GVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLP 1007 Query: 236 GPGGVAGAAGKAGYPTGTGV----GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVP 291 GP G G G G P GV GPQ + AK G AG PG+G +PG+ Sbjct: 1008 GPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGP-PGIG---IPGLR 1063 Query: 292 GAIPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGF--GPGVVGVPGA-GVP 347 G G GIAG G+P K K +PG PG PG VG PG+ G+P Sbjct: 1064 GE-KGDQGIAGFPGSPGE--------KGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLP 1114 Query: 348 GV----GVPGA-GIPVVPG-AGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPT 401 G G+PG GIP V G AG+PG PG P G+ G G+P Sbjct: 1115 GEKGDKGLPGLDGIPGVKGEAGLPGT--PGPTGPAGQKGEPGSDGIPGSAGEKGEPGLP- 1171 Query: 402 YGVGAGGFPGF-----GVGVGGIPGVAGVPGVGGV------------------------- 431 G G GFPG G G PG+AG PG+ G Sbjct: 1172 -GRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHA 1230 Query: 432 -------------PGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGL 478 PG+ G+PG P K K G P A F Sbjct: 1231 TEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQG 1290 Query: 479 VPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGV----------GVAPGVGVAPGIGPGG 528 +PG+G +PG+ + G PGV G PG+ GV G+ GP G Sbjct: 1291 MPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPG 1350 Query: 529 VAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAV 588 K + GL G+PG GV GL G+PG G+PGF Sbjct: 1351 PYDIIKGEPGLPGPEGPPGLKGL-QGLPGPKGQQGVTGL---VGIPG---PPGIPGFDGA 1403 Query: 589 PGALAAAKAAKYGAAVP-GVLGGLGALGGVGIPGGV 623 PG + + G A P G G G G G+PG + Sbjct: 1404 PG-----QKGEMGPAGPTGPRGFPGPPGPDGLPGSM 1434 Score = 142 bits (358), Expect = 1e-33 Identities = 220/723 (30%), Positives = 260/723 (35%), Gaps = 111/723 (15%) Query: 22 HPSRPGGVPGAIPG--GVPGGVFYPGAGLGALGGGALGPGGKPL---KPVPGGLAGAGLG 76 +P PG +PG IPG G PG PG G LGP G P P P GL G Sbjct: 101 YPGNPG-LPG-IPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGD 158 Query: 77 AG--LGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVV 134 G LG P + G + G+ G PG GL P P Sbjct: 159 PGEILGHVPGMLLKGE----------------RGFPGIPGTPGPPGLPGLQGPVGPPGFT 202 Query: 135 PQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAP-------GV 187 PG PG G G+ G GV PGVP A V+ K G Sbjct: 203 GPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQ 262 Query: 188 GG--AFAGIPGVGPFGGPQPGVPLGYPIK--------APKLPGGYGLPYTTGKLPYGYGP 237 G F G+PGVG G P P G P K +P PG G P G+ GP Sbjct: 263 KGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGR----QGP 318 Query: 238 GGVAGAAGKAGYP-TGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPG 296 G G AG G P G GP + + G G G G PG+PG PG Sbjct: 319 QGEKGEAGPPGPPGIVIGTGP------LGEKGERGYPGTPGPRGEPGPKGFPGLPGQ-PG 371 Query: 297 IGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFG--PGVVGVPGA-GVPGV---- 349 G+ G A + G +PG G PG G PG G PG Sbjct: 372 PPGLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGI 431 Query: 350 -----GVPG-AGIPVVPGAGIPG-AAVPGVVSPEAAAKAAAKAAKYGARPG-------VG 395 G PG G P +PG PG G + + Y PG +G Sbjct: 432 VECQPGPPGDQGPPGIPGQ--PGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIG 489 Query: 396 VGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAA 455 G P G G PG GV G+PG G PG+ G PG G PG E K Sbjct: 490 FPGQPG-AKGDRGLPGRD-GVAGVPGPQGTPGLIGQPGAKGEPG-----EFYFDLRLKGD 542 Query: 456 KYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPG-VGVAPGVGLAPGVGVAPGVGV 514 K G P A + PG+ PG +PG VG+ G GVG PG Sbjct: 543 KGDPGFPGQPGMTGRAGSPGRDGHPGL---PGPKGSPGSVGLKGERGPPGGVGF-PGSRG 598 Query: 515 APGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVP 574 G PG GP G + K Q A G G PGL G PG V +P Sbjct: 599 DTGPPGPPGYGPAG---------PIGDKGQ--AGFPGGPGSPGLPGPKGEPGKIV--PLP 645 Query: 575 GLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALG--GVGIPG--GVVGA-GPA 629 G G+PG PG + PG+ G GA+G G+G PG G G G Sbjct: 646 GPPGAEGLPGSPGFPGP-QGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLP 704 Query: 630 AAAAAAKAAAKAAQFGLVGAAGL-GGLGVGGLGVPGVGGLGGIP--PAAAAKAAKYGVAA 686 + GL G G+ G G G+G+PG+ GL G+P P + GV Sbjct: 705 GDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPG 764 Query: 687 RPG 689 PG Sbjct: 765 VPG 767 Score = 115 bits (289), Expect = 1e-25 Identities = 151/487 (31%), Positives = 185/487 (37%), Gaps = 104/487 (21%) Query: 23 PSRPGGVPGAIPG--GVPGGVFYPGAGLGALGGGALG--PGGKPLKPVPGGLAGAGLGAG 78 P +PG P PG G PG PG G++GG L PG K + +PG GL Sbjct: 986 PGQPG--PKGDPGISGTPGAPGLPGPK-GSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGD 1042 Query: 79 LGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG----LGVSAAPSVPGAVV 134 GA G P G+ + K G+ G PG G G P +PG+ Sbjct: 1043 KGAKGE---KGQAGPPGIG--IPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGS-- 1095 Query: 135 PQPGAGVKPGKVPGVGLPGVYPGGVLPGAR----FPGVGVLPGVPTGAGVKPKAPGVGGA 190 PG PG V G PG LPG + PG+ +PGV AG+ P PG G Sbjct: 1096 --PGLKGSPGSVGYPGSPG------LPGEKGDKGLPGLDGIPGVKGEAGL-PGTPGPTGP 1146 Query: 191 FA--------GIPGVGPFGGPQPGVP-LGYP--------------IKAPKLPGGYGLPYT 227 GIPG G +PG+P G+P + P L G G+P + Sbjct: 1147 AGQKGEPGSDGIPGSAGEKG-EPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGS 1205 Query: 228 TGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGV--LPGVGGA 285 G+ + GP G G G G P GP+ + G G LPG+ G Sbjct: 1206 KGEQGF-MGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGV 1264 Query: 286 ----GVPGVPGAIPGIGGIAG----VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPG 337 G PG PGA PG+ G G G P + G PG PGF G Sbjct: 1265 KGDKGNPGWPGA-PGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGP-----PGVPGF-QG 1317 Query: 338 VVGVPGA-GVPG----VGVPGA-GIPVVPGA--------GIPGAAVPGVVSPEAAAKAAA 383 G+PG G+ G GVPGA G+P PG G PG +PG P Sbjct: 1318 PKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPG--LPGPEGPPGLKGLQG 1375 Query: 384 KAAKYGARPGVGVGGIPTYGVGAGGFPGFG-----------VGVGGIPGVAGVPGVGGVP 432 G + G+ GIP G G PGF G G G G PG G+P Sbjct: 1376 LPGPKGQQGVTGLVGIP----GPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPDGLP 1431 Query: 433 GVGGVPG 439 G G PG Sbjct: 1432 GSMGPPG 1438 Score = 73.6 bits (179), Expect = 6e-13 Identities = 88/300 (29%), Positives = 109/300 (36%), Gaps = 25/300 (8%) Query: 407 GGFPGFGVG---VGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPA 463 GG G G G G+ G G G+ G+ GV G PG+ Q K G P Sbjct: 29 GGCAGSGCGKCDCHGVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPG 88 Query: 464 AAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGV-GVAP 522 + A+ + PG+ PG PG PG+ G G PG+ G A Sbjct: 89 TKGTRGPPGASGYPGNPGLPGIPGQDGPPG---PPGIPGCNGTKGERGPLGPPGLPGFAG 145 Query: 523 GIGPGGVAAAAKSAAKVAAKAQ---LRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVG 579 GP G+ ++ L+ G GIPG G+PGL G PG Sbjct: 146 NPGPPGLPGMKGDPGEILGHVPGMLLKGERGF-PGIPGTPGPPGLPGLQGPVGPPGFTGP 204 Query: 580 AGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAA 639 G PG PG + + G + G G G G G PG G A A Sbjct: 205 PGPPGPPGPPG-----EKGQMGLSFQGPKGDKGDQGVSGPPG---VPGQAQVQEKGDFAT 256 Query: 640 KAAQFGLVGAAGLGGL-GVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPG 698 K + G G G G+ GVG G PG G G P K G PGF P +PG Sbjct: 257 KGEK-GQKGEPGFQGMPGVGEKGEPGKPGPRGKP----GKDGDKGEKGSPGFPGEPGYPG 311 Score = 33.1 bits (74), Expect = 0.92 Identities = 41/135 (30%), Positives = 49/135 (36%), Gaps = 29/135 (21%) Query: 28 GVPGAIPGGVPGGVFYPGA-----GLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAF 82 GVPGA G+PG PG G L G PG K L+ +PG G+ +G Sbjct: 1335 GVPGA--KGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVG-- 1390 Query: 83 PAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVVPQPGAGVK 142 PG P G+ G G PG G A P+ P PG Sbjct: 1391 ----IPG---PPGIP-------------GFDGAPGQKGEMGPAGPTGPRGFPGPPGPDGL 1430 Query: 143 PGKVPGVGLPGVYPG 157 PG + G P V G Sbjct: 1431 PGSMGPPGTPSVDHG 1445 >gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo sapiens] Length = 1691 Score = 169 bits (428), Expect = 8e-42 Identities = 219/741 (29%), Positives = 271/741 (36%), Gaps = 139/741 (18%) Query: 28 GVPGAIPGGVPGGVFYPGAGLGALGG-GALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVT 86 G PG P G+ G PG G G G G GKP K G G Sbjct: 267 GPPG--PPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPG-------------- 310 Query: 87 FPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG----LGVSAAPSVPGAVVPQPGAGVK 142 +PG D G G PG G G + P PG V+P+PG G+ Sbjct: 311 -----IPGLPGDP-----------GYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGIT 354 Query: 143 PGKVPGVGLPGVYPGGVLPGAR----FPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVG 198 G+ +GLPG LPG + FPG+ PG+P G P F G G Sbjct: 355 IGEKGNIGLPG------LPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQK 408 Query: 199 PFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYG-----------YGPGGVAGAAGKA 247 GP PG+ + P PG GLP G P G GP G G+ G Sbjct: 409 GDEGP-PGISIPGPPGLDGQPGAPGLPGPPG--PAGPHIPPSDEICEPGPPGPPGSPGDK 465 Query: 248 GYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPA 307 G GV K F G+ G G+PG+PG +G G Sbjct: 466 GLQGEQGV-------KGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKG 518 Query: 308 AAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-----AGVPG----VGVPGA-GIP 357 A A GA PG PGF PG G PG G+ G +G PGA G+P Sbjct: 519 QAGATGPKGLPGIPGA-----PGAPGF-PGSKGEPGDILTFPGMKGDKGELGSPGAPGLP 572 Query: 358 VVPGAGIPGA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFG--- 413 +PG PG +PG+ P+ + G G+ G+P +G G PGFG Sbjct: 573 GLPGT--PGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPG-NIGPMGPPGFGPPG 629 Query: 414 -VGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYG-------------V 459 VG GI GVAG PG G+PG G PG I+ + + G Sbjct: 630 PVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQP 689 Query: 460 GTPAAAAAKAAAKAAQFGL--VPGVGVAPGVGVAPGVGVAPG-VGL--APGVGVAPGVGV 514 G P +K GL PG PG+ PG PG +GL PG PG Sbjct: 690 GLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKG 749 Query: 515 APGVGVAPGIGPGGV-----AAAAKSAAKVAAKAQLRAAAGLGA-----------GIPGL 558 PG + GP G+ A K GL G PG Sbjct: 750 EPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGP 809 Query: 559 GVGVGVPGLGVGA--GVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGG 616 G+PG+GV G PG+ G PG +PG G VPG G G+ G Sbjct: 810 MGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPG--EKGDPGPPGLDVPGPPGERGSPGI 867 Query: 617 VGIPGGVVGAG----PAAAAAAAKAAAKAAQFGLVGAAG-LGGLGV-GGLGVPGVGGLGG 670 G PG + G P A A+ K + G++G G G LG+ G GVPG+ G G Sbjct: 868 PGAPGPIGPPGSPGLPGKAGASGFPGTK-GEMGMMGPPGPPGPLGIPGRSGVPGLKGDDG 926 Query: 671 I--PPAAAAKAAKYGVAARPG 689 + P + G PG Sbjct: 927 LQGQPGLPGPTGEKGSKGEPG 947 Score = 162 bits (411), Expect = 8e-40 Identities = 216/695 (31%), Positives = 251/695 (36%), Gaps = 112/695 (16%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGG--GALGPGGKPLKPVPGGLAGAGLGAGLG 80 P P G PG P G PG G L G GALGP G P P G G GL Sbjct: 738 PPGPPGFPG--PKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGR---TGLD 792 Query: 81 AFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVVP--QPG 138 P G + P G G G PG+ G+GV P PG P QPG Sbjct: 793 GLPGPK--GDVGPNGQP-------------GPMGPPGLPGIGVQGPPGPPGIPGPIGQPG 837 Query: 139 AGVKPGKVPGVGLPGVYPGGVLPGAR-FPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPG- 196 PG+ G PG+ G PG R PG+ PG P G P PG GA +G PG Sbjct: 838 LHGIPGEKGDPGPPGLDVPGP-PGERGSPGIPGAPG-PIGPPGSPGLPGKAGA-SGFPGT 894 Query: 197 ---VGPFGGPQPGVPLGYPIKA--PKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPT 251 +G G P P PLG P ++ P L G GL G LP GP G G+ G+ G P Sbjct: 895 KGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPG-LP---GPTGEKGSKGEPGLP- 949 Query: 252 GTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGV-GTPAAAA 310 GP G +L G G PG+PG IPG+ G G G P Sbjct: 950 ----GPP-------------GPMDPNLLGSKGEKGEPGLPG-IPGVSGPKGYQGLPGDPG 991 Query: 311 AAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIPGAAVP 370 + + G P GP PG+ G PG +G PG + G PG Sbjct: 992 QPGLSGQPGLPG------PPGPKGNPGLPGQPGL----IGPPGLK-GTIGDMGFPGPQ-- 1038 Query: 371 GVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGG 430 GV P + + G G G P G+ + G PG G G PG+ G PG G Sbjct: 1039 GVEGPPGPSGVPGQPGSPGLPGQKGDKGDP--GISSIGLPGLP-GPKGEPGLPGYPGNPG 1095 Query: 431 VPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGV 490 + G G PG+ P A GTP K + +PG G G Sbjct: 1096 IKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGG 1155 Query: 491 APGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAG 550 PG PG PG PG G PG G G Sbjct: 1156 HPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPG---------------------- 1193 Query: 551 LGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALA-AAKAAKYGAAVPGVLG 609 G+PGL G GL G PGL G PGF PG G A+ G G Sbjct: 1194 -PPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKG 1252 Query: 610 GLGALGGVGIPG-----GVVG-AGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVP 663 G G G PG G+ G GP + G G GL GL G G P Sbjct: 1253 NPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGL-KGDQGPP 1311 Query: 664 GVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPG 698 G+ G G P G+ PG P FPG Sbjct: 1312 GLQGNPGRP-------GLNGMKGDPGLPGVPGFPG 1339 Score = 162 bits (411), Expect = 8e-40 Identities = 213/689 (30%), Positives = 261/689 (37%), Gaps = 89/689 (12%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGA----GLGALGG--GALGPGGKPLKPVPGGLAGAGLG 76 P P G+PG G PG PG GL + G G GP G + PG G+ Sbjct: 809 PMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIP 868 Query: 77 AGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG-LGVSAAPSVPG---- 131 G PG +PG A+ + K G+ G PG G LG+ VPG Sbjct: 869 GAPGPIGPPGSPG--LPGKAG--ASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGD 924 Query: 132 -AVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGG- 189 + QPG G+ G PG+ PG PG P + G G+ P PGV G Sbjct: 925 DGLQGQPGLPGPTGEKGSKGEPGL-PGP--PGPMDPNLLGSKGEKGEPGL-PGIPGVSGP 980 Query: 190 -AFAGIPGVG--PFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGK 246 + G+PG P QPG+P G P PK G GLP G + GP G+ G G Sbjct: 981 KGYQGLPGDPGQPGLSGQPGLP-GPP--GPK--GNPGLPGQPGLI----GPPGLKGTIGD 1031 Query: 247 AGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVL--PGVGGAGVPGVPG--------AIP 295 G+P GV GP + + + G G PG+ G+PG+PG P Sbjct: 1032 MGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYP 1091 Query: 296 GIGGIAG-VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG----AGVPG-V 349 G GI G VG P + PG PGF PG G PG +G PG Sbjct: 1092 GNPGIKGSVGDPGLPGLPGTPGAKGQ--------PGLPGF-PGTPGPPGPKGISGPPGNP 1142 Query: 350 GVPGAGIPVVPGAGIPGAAVP----GVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVG 405 G+PG PV G G PG P G + A + + G +PG G G P G Sbjct: 1143 GLPGEPGPV-GGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPG-QPGFGNPGPPGLP-G 1199 Query: 406 AGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAA 465 G G G G+ GIPG G+PG G PG G PGV P + A + G P Sbjct: 1200 LSGQKGDG-GLPGIPGNPGLPGPKGEPGFHGFPGVQ-GPPGPPGSPGPALEGPKGNPGPQ 1257 Query: 466 AAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIG 525 F +PG PG+ PG G G PG PG+ G PG+ Sbjct: 1258 GPPGRPGPTGFQGLPGPEGPPGL---PGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGL- 1313 Query: 526 PGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGF 585 G + K G PGL G PG+ +GVPG G PG Sbjct: 1314 QGNPGRPGLNGMK---------------GDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGL 1358 Query: 586 GAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFG 645 PG + + G G G G G+ G GP + G Sbjct: 1359 IGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNG 1418 Query: 646 LVGAAGLGG-LGVGGL-GVPGVGGLGGIP 672 L G G GG G GL G PG GL G P Sbjct: 1419 LPGFDGAGGRKGDPGLPGQPGTRGLDGPP 1447 Score = 138 bits (348), Expect = 2e-32 Identities = 208/729 (28%), Positives = 263/729 (36%), Gaps = 120/729 (16%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGA-GLGALGG--GALGPGGKPLKPVPG--GLAGAGLGA 77 P P G+ G P G+PG +PG GL + G GA GP G +PG G G Sbjct: 85 PPGPKGIRG--PPGLPG---FPGTPGLPGMPGHDGAPGPQG-----IPGCNGTKGERGFP 134 Query: 78 GLGAFPAVTFPGAL--VPGGVADAAAAYKAAKAGA----------GLGGVPGVGGLGVSA 125 G FP + P +PG + + ++ G G+ G+PG G+ Sbjct: 135 GSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPI 194 Query: 126 APSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAP 185 P P ++ PG PG +GL P G G P P G + K P Sbjct: 195 GPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQG----PPGPPGQISEQKRP 250 Query: 186 GVGGAF----AGIPG-VGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGK--LPYGYGPG 238 + F G+PG GP G P P G P G G P GK G Sbjct: 251 -IDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQP 309 Query: 239 GVAGAAGKAGYPTGTG----VGPQAAAAAAAKAAAKFGAGAAGVLPG-VGGAGVPGVPG- 292 G+ G G GYP G G + G+ G G G+PG+PG Sbjct: 310 GIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGE 369 Query: 293 ----AIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AGVP 347 PGI G G+ P AA PG PGF PG G G G P Sbjct: 370 KGERGFPGIQGPPGLPGPPGAAVMGP--------------PGPPGF-PGERGQKGDEGPP 414 Query: 348 GVGVPGA----GIPVVPG-AGIPGAAVPGVVSPEAAAKAA-----AKAAKYGARPGVGVG 397 G+ +PG G P PG G PG A P + + + G + GV Sbjct: 415 GISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVK 474 Query: 398 GIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKY 457 G G F G G+ G PG G+PG+ G PG G PG + A A K Sbjct: 475 G----DKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPG---QKGEKGQAGATGPKG 527 Query: 458 GVGTPAAAAAKAAAKAAQFGLVPGVGVAPG-VGVAPGVGVAPGVGLAPGVGVAPGVGVAP 516 G P A A PG PG + PG+ G +PG PG+ P Sbjct: 528 LPGIPGAPGAPG---------FPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTP 578 Query: 517 GVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRAAAGLG-AGIPGLGVGVGVPGLGV--GAG 572 G PG+ GP G + K + G G+PG +G PG G G Sbjct: 579 GQDGLPGLPGPKG------EPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVG 632 Query: 573 VPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAA 632 G+ AG PG +PG PG+ G G G VG+PG G Sbjct: 633 EKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLP 692 Query: 633 AAAKAAAKAAQFGLVGAAGLGGL-GVGGLGVPGVGGLGGI--PPAAAAKAAKYGVAARPG 689 G+ G+ G G+ G+G G PG G GI PP A + G+ PG Sbjct: 693 ------------GIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPG 740 Query: 690 FGLSPIFPG 698 P FPG Sbjct: 741 ---PPGFPG 746 Score = 138 bits (348), Expect = 2e-32 Identities = 202/652 (30%), Positives = 239/652 (36%), Gaps = 118/652 (18%) Query: 23 PSRPG-----GVPGAI-PGGVPGGVFYPG-AGLGALGG-----GALGPGGKP-------L 63 P PG G+PGA P G PG PG AG G G +GP G P Sbjct: 856 PGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGR 915 Query: 64 KPVPG-----GLAGA-GLGAGLGAFPAVTFPGALVPGGVADA-AAAYKAAKAGAGLGGVP 116 VPG GL G GL G + PG P G D K K GL G+P Sbjct: 916 SGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIP 975 Query: 117 GVGG-LGVSAAPSVPG--AVVPQPGAGVKPGKVPGVGLPGVYPG--------GVLPGARF 165 GV G G P PG + QPG PG GLPG PG G + F Sbjct: 976 GVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPG-QPGLIGPPGLKGTIGDMGF 1034 Query: 166 PGVGVLPGVPTGAGV--KPKAPGVGGAFA--GIPGVGPFGGPQPGVPLGYPIKAPKLPGG 221 PG + G P +GV +P +PG+ G G PG+ G P P G P P PG Sbjct: 1035 PGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEP-GLPGYPGN 1093 Query: 222 YGLPYTTGK--LPYGYGPGGVAGAAGKAGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGV 278 G+ + G LP G G G G G+P G GP+ + G G Sbjct: 1094 PGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNP------GLPGE 1147 Query: 279 LPGVGGAGVPGVPGAIPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFG-P 336 VGG G PG PG PG G G G P A PG PGFG P Sbjct: 1148 PGPVGGGGHPGQPGP-PGEKGKPGQDGIPGPAGQKGE--------------PGQPGFGNP 1192 Query: 337 GVVGVPG-------AGVPGV----GVPGA-------GIPVVPGA-GIPGAAVPGVVSPEA 377 G G+PG G+PG+ G+PG G P V G G PG+ P + P+ Sbjct: 1193 GPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKG 1252 Query: 378 AAKAAAKAAKYGARPG-VGVGGIPTYGVGAGGFPGFG--VGVGGIPGVAGVPGVGGVPGV 434 RPG G G+P G G PG G G G PG G+PG+ G+ G Sbjct: 1253 NPGPQGPPG----RPGPTGFQGLPG-PEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGD 1307 Query: 435 GGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVA---PGVGVA 491 G PG+ +P K G P K + VPG PG+ Sbjct: 1308 QGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSG------VPGSAGPEGEPGLIGP 1361 Query: 492 PGVGVAPGVG----LAPGVGVAPGVGVAPGVGVAPGI-GPGGVAAAAKSAAKVAAKAQLR 546 PG PG + G PG+ PG+ PG GP G+ Sbjct: 1362 PGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRN---- 1417 Query: 547 AAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAA 598 GL G G G G PGL G GL G G PG + A Sbjct: 1418 ---GL-PGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVA 1465 Score = 90.1 bits (222), Expect = 6e-18 Identities = 154/561 (27%), Positives = 193/561 (34%), Gaps = 101/561 (18%) Query: 205 PGVPLGYPIKAPKLPGGYGLPYTTGK-----LPYGYGPGGVAGAAGKAGYPTGTGVGPQA 259 PG+ G+P P PG G P G+ +P GP G+ G G G+P G Sbjct: 53 PGLE-GHP-GLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFP-----GTPG 105 Query: 260 AAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAG-VGTPAAAAAAAAAAKA 318 A G G G G PG PG PG+ G G G P + + Sbjct: 106 LPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPG-FPGLQGPPGPPGIPGMKGEPGSIIMS 164 Query: 319 AKYGAAAGLVPGGPGFGPGVVGVPG-AGVPG-VGVPGAGIPVVPG-AGIPGAAVPGVVSP 375 + G PG PG PG+ G+PG G+PG +G PG PG G PG PG+ P Sbjct: 165 SLPGPKGN--PGYPG-PPGIQGLPGPTGIPGPIGPPGP-----PGLMGPPGP--PGLPGP 214 Query: 376 EAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPG------------FGVGVGGIPGVA 423 + + K G + G+ G P G PG F G G+PG Sbjct: 215 KGNMGLNFQGPK-GEKGEQGLQGPP-------GPPGQISEQKRPIDVEFQKGDQGLPGDR 266 Query: 424 GVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYG-------------------VGTPAA 464 G PG G+ G G PG + + K K G G P Sbjct: 267 GPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGR 326 Query: 465 AAAKAAAKAAQFGLVPGVGV-APGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG 523 K PG+ + PG G+ +G +GL PG+ G PG+ PG Sbjct: 327 DGEKGQKGDTGPPGPPGLVIPRPGTGIT--IGEKGNIGL-PGLPGEKGERGFPGIQGPPG 383 Query: 524 IGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAG-- 581 + PG AA R G G PG+ + G PGL G PGL G Sbjct: 384 L-PGPPGAAVMGPPGPPGFPGERGQKG-DEGPPGISI-PGPPGLDGQPGAPGLPGPPGPA 440 Query: 582 -----------VPGFGAVPGALAAAKAAKYGAAVPGVLG-------GLGALGGVGIPGGV 623 PG PG+ K + V G G G G G G PG Sbjct: 441 GPHIPPSDEICEPGPPGPPGS-PGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLP 499 Query: 624 VGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIP------PAAAA 677 GP + + Q G G GL G+ G G PG G G P P Sbjct: 500 GLPGPPGSLGFPGQKGEKGQAGATGPKGLPGI-PGAPGAPGFPGSKGEPGDILTFPGMKG 558 Query: 678 KAAKYGVAARPGFGLSPIFPG 698 + G PG P PG Sbjct: 559 DKGELGSPGAPGLPGLPGTPG 579 Score = 65.1 bits (157), Expect = 2e-10 Identities = 115/432 (26%), Positives = 142/432 (32%), Gaps = 66/432 (15%) Query: 296 GIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPGVGVPGA 354 G+ AG+ A + A AA YG + PG G+ G G G PG+ Sbjct: 5 GVSLAAGLFLLALSLWGQPAEAAACYGCS----PGSKCDCSGIKGEKGERGFPGL----- 55 Query: 355 GIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGV 414 G PG +PG PE G R G GIP G PG Sbjct: 56 -------EGHPG--LPGFPGPEGPP---------GPRGQKGDDGIP-------GPPG--- 87 Query: 415 GVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAA 474 GI G G+PG G PG+ G+PG +P Q K G P + Sbjct: 88 -PKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPP 146 Query: 475 QFGLVPGVGVAPG---VGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG----IGPG 527 +PG+ PG + PG PG PG+ PG PG PG +GP Sbjct: 147 GPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPP 206 Query: 528 GVAAAAKSAAKVAAKAQ----------LRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLG 577 G + Q L+ G I + V G+PG Sbjct: 207 GPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDR 266 Query: 578 VGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKA 637 G PG PG K K PG G G G G PG G Sbjct: 267 GPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGR 326 Query: 638 AAKAAQFGLVGAAGLGGL-----GVG-GLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFG 691 + Q G G G GL G G +G G GL G+P + G+ PG Sbjct: 327 DGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFP-GIQGPPGL- 384 Query: 692 LSPIFPGGACLG 703 P PG A +G Sbjct: 385 --PGPPGAAVMG 394 >gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sapiens] Length = 1685 Score = 169 bits (428), Expect = 8e-42 Identities = 219/741 (29%), Positives = 271/741 (36%), Gaps = 139/741 (18%) Query: 28 GVPGAIPGGVPGGVFYPGAGLGALGG-GALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVT 86 G PG P G+ G PG G G G G GKP K G G Sbjct: 267 GPPG--PPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPG-------------- 310 Query: 87 FPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG----LGVSAAPSVPGAVVPQPGAGVK 142 +PG D G G PG G G + P PG V+P+PG G+ Sbjct: 311 -----IPGLPGDP-----------GYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGIT 354 Query: 143 PGKVPGVGLPGVYPGGVLPGAR----FPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVG 198 G+ +GLPG LPG + FPG+ PG+P G P F G G Sbjct: 355 IGEKGNIGLPG------LPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQK 408 Query: 199 PFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYG-----------YGPGGVAGAAGKA 247 GP PG+ + P PG GLP G P G GP G G+ G Sbjct: 409 GDEGP-PGISIPGPPGLDGQPGAPGLPGPPG--PAGPHIPPSDEICEPGPPGPPGSPGDK 465 Query: 248 GYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPA 307 G GV K F G+ G G+PG+PG +G G Sbjct: 466 GLQGEQGV-------KGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKG 518 Query: 308 AAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-----AGVPG----VGVPGA-GIP 357 A A GA PG PGF PG G PG G+ G +G PGA G+P Sbjct: 519 QAGATGPKGLPGIPGA-----PGAPGF-PGSKGEPGDILTFPGMKGDKGELGSPGAPGLP 572 Query: 358 VVPGAGIPGA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFG--- 413 +PG PG +PG+ P+ + G G+ G+P +G G PGFG Sbjct: 573 GLPGT--PGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPG-NIGPMGPPGFGPPG 629 Query: 414 -VGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYG-------------V 459 VG GI GVAG PG G+PG G PG I+ + + G Sbjct: 630 PVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQP 689 Query: 460 GTPAAAAAKAAAKAAQFGL--VPGVGVAPGVGVAPGVGVAPG-VGL--APGVGVAPGVGV 514 G P +K GL PG PG+ PG PG +GL PG PG Sbjct: 690 GLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKG 749 Query: 515 APGVGVAPGIGPGGV-----AAAAKSAAKVAAKAQLRAAAGLGA-----------GIPGL 558 PG + GP G+ A K GL G PG Sbjct: 750 EPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGP 809 Query: 559 GVGVGVPGLGVGA--GVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGG 616 G+PG+GV G PG+ G PG +PG G VPG G G+ G Sbjct: 810 MGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPG--EKGDPGPPGLDVPGPPGERGSPGI 867 Query: 617 VGIPGGVVGAG----PAAAAAAAKAAAKAAQFGLVGAAG-LGGLGV-GGLGVPGVGGLGG 670 G PG + G P A A+ K + G++G G G LG+ G GVPG+ G G Sbjct: 868 PGAPGPIGPPGSPGLPGKAGASGFPGTK-GEMGMMGPPGPPGPLGIPGRSGVPGLKGDDG 926 Query: 671 I--PPAAAAKAAKYGVAARPG 689 + P + G PG Sbjct: 927 LQGQPGLPGPTGEKGSKGEPG 947 Score = 165 bits (417), Expect = 2e-40 Identities = 214/689 (31%), Positives = 248/689 (35%), Gaps = 106/689 (15%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGG--GALGPGGKPLKPVPGGLAGAGLGAGLG 80 P P G PG P G PG G L G GALGP G P P G G GL Sbjct: 738 PPGPPGFPG--PKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGR---TGLD 792 Query: 81 AFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVVP--QPG 138 P G + P G G G PG+ G+GV P PG P QPG Sbjct: 793 GLPGPK--GDVGPNGQP-------------GPMGPPGLPGIGVQGPPGPPGIPGPIGQPG 837 Query: 139 AGVKPGKVPGVGLPGVYPGGVLPGAR-FPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPG- 196 PG+ G PG+ G PG R PG+ PG P G P PG GA +G PG Sbjct: 838 LHGIPGEKGDPGPPGLDVPGP-PGERGSPGIPGAPG-PIGPPGSPGLPGKAGA-SGFPGT 894 Query: 197 ---VGPFGGPQPGVPLGYPIKA--PKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPT 251 +G G P P PLG P ++ P L G GL G LP GP G G+ G+ G P Sbjct: 895 KGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPG-LP---GPTGEKGSKGEPGLP- 949 Query: 252 GTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGV-GTPAAAA 310 GP G +L G G PG+PG IPG+ G G G P Sbjct: 950 ----GPP-------------GPMDPNLLGSKGEKGEPGLPG-IPGVSGPKGYQGLPGDPG 991 Query: 311 AAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIPGAAVP 370 + + G P GP PG+ G PG +G PG + G PG Sbjct: 992 QPGLSGQPGLPG------PPGPKGNPGLPGQPGL----IGPPGLK-GTIGDMGFPGPQ-- 1038 Query: 371 GVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGG 430 GV P + + G G G P G+ + G PG G G PG+ G PG G Sbjct: 1039 GVEGPPGPSGVPGQPGSPGLPGQKGDKGDP--GISSIGLPGLP-GPKGEPGLPGYPGNPG 1095 Query: 431 VPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGV 490 + G G PG+ P A GTP K + +PG G G Sbjct: 1096 IKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGG 1155 Query: 491 APGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAG 550 PG PG PG PG G PG G G Sbjct: 1156 HPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPG---------------------- 1193 Query: 551 LGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALA-AAKAAKYGAAVPGVLG 609 G+PGL G GL G PGL G PGF PG G A+ G G Sbjct: 1194 -PPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKG 1252 Query: 610 GLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLG 669 G G G PG GP + G G GL GL G G PG+ G Sbjct: 1253 NPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGL-KGDQGPPGLQGNP 1311 Query: 670 GIPPAAAAKAAKYGVAARPGFGLSPIFPG 698 G P G+ PG P FPG Sbjct: 1312 GRP-------GLNGMKGDPGLPGVPGFPG 1333 Score = 138 bits (348), Expect = 2e-32 Identities = 208/729 (28%), Positives = 263/729 (36%), Gaps = 120/729 (16%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGA-GLGALGG--GALGPGGKPLKPVPG--GLAGAGLGA 77 P P G+ G P G+PG +PG GL + G GA GP G +PG G G Sbjct: 85 PPGPKGIRG--PPGLPG---FPGTPGLPGMPGHDGAPGPQG-----IPGCNGTKGERGFP 134 Query: 78 GLGAFPAVTFPGAL--VPGGVADAAAAYKAAKAGA----------GLGGVPGVGGLGVSA 125 G FP + P +PG + + ++ G G+ G+PG G+ Sbjct: 135 GSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPI 194 Query: 126 APSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAP 185 P P ++ PG PG +GL P G G P P G + K P Sbjct: 195 GPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQG----PPGPPGQISEQKRP 250 Query: 186 GVGGAF----AGIPG-VGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGK--LPYGYGPG 238 + F G+PG GP G P P G P G G P GK G Sbjct: 251 -IDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQP 309 Query: 239 GVAGAAGKAGYPTGTG----VGPQAAAAAAAKAAAKFGAGAAGVLPG-VGGAGVPGVPG- 292 G+ G G GYP G G + G+ G G G+PG+PG Sbjct: 310 GIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGE 369 Query: 293 ----AIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AGVP 347 PGI G G+ P AA PG PGF PG G G G P Sbjct: 370 KGERGFPGIQGPPGLPGPPGAAVMGP--------------PGPPGF-PGERGQKGDEGPP 414 Query: 348 GVGVPGA----GIPVVPG-AGIPGAAVPGVVSPEAAAKAA-----AKAAKYGARPGVGVG 397 G+ +PG G P PG G PG A P + + + G + GV Sbjct: 415 GISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVK 474 Query: 398 GIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKY 457 G G F G G+ G PG G+PG+ G PG G PG + A A K Sbjct: 475 G----DKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPG---QKGEKGQAGATGPKG 527 Query: 458 GVGTPAAAAAKAAAKAAQFGLVPGVGVAPG-VGVAPGVGVAPGVGLAPGVGVAPGVGVAP 516 G P A A PG PG + PG+ G +PG PG+ P Sbjct: 528 LPGIPGAPGAPG---------FPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTP 578 Query: 517 GVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRAAAGLG-AGIPGLGVGVGVPGLGV--GAG 572 G PG+ GP G + K + G G+PG +G PG G G Sbjct: 579 GQDGLPGLPGPKG------EPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVG 632 Query: 573 VPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAA 632 G+ AG PG +PG PG+ G G G VG+PG G Sbjct: 633 EKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLP 692 Query: 633 AAAKAAAKAAQFGLVGAAGLGGL-GVGGLGVPGVGGLGGI--PPAAAAKAAKYGVAARPG 689 G+ G+ G G+ G+G G PG G GI PP A + G+ PG Sbjct: 693 ------------GIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPG 740 Query: 690 FGLSPIFPG 698 P FPG Sbjct: 741 ---PPGFPG 746 Score = 137 bits (346), Expect = 3e-32 Identities = 196/650 (30%), Positives = 235/650 (36%), Gaps = 120/650 (18%) Query: 23 PSRPG-----GVPGAI-PGGVPGGVFYPG-AGLGALGG-----GALGPGGKP-------L 63 P PG G+PGA P G PG PG AG G G +GP G P Sbjct: 856 PGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGR 915 Query: 64 KPVPG-----GLAGA-GLGAGLGAFPAVTFPGALVPGGVADA-AAAYKAAKAGAGLGGVP 116 VPG GL G GL G + PG P G D K K GL G+P Sbjct: 916 SGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIP 975 Query: 117 GVGG-LGVSAAPSVPG--AVVPQPGAGVKPGKVPGVGLPGVYPG--------GVLPGARF 165 GV G G P PG + QPG PG GLPG PG G + F Sbjct: 976 GVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPG-QPGLIGPPGLKGTIGDMGF 1034 Query: 166 PGVGVLPGVPTGAGV--KPKAPGVGGAFA--GIPGVGPFGGPQPGVPLGYPIKAPKLPGG 221 PG + G P +GV +P +PG+ G G PG+ G P P G P P PG Sbjct: 1035 PGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEP-GLPGYPGN 1093 Query: 222 YGLPYTTGK--LPYGYGPGGVAGAAGKAGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGV 278 G+ + G LP G G G G G+P G GP+ + G G Sbjct: 1094 PGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNP------GLPGE 1147 Query: 279 LPGVGGAGVPGVPGAIPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFG-P 336 VGG G PG PG PG G G G P A PG PGFG P Sbjct: 1148 PGPVGGGGHPGQPGP-PGEKGKPGQDGIPGPAGQKGE--------------PGQPGFGNP 1192 Query: 337 GVVGVPG-------AGVPGV----GVPGA-------GIPVVPGA-GIPGAAVPGVVSPEA 377 G G+PG G+PG+ G+PG G P V G G PG+ P + P+ Sbjct: 1193 GPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKG 1252 Query: 378 AAKAAAKAAKYGARPGVGVGGIPTYG-----VGAGGFPGFGVGVGGIPGVAGVPGVGGVP 432 + G G G+P G G G PG G+ G+ G G PG+ G P Sbjct: 1253 NPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLP-GLPGLKGDQGPPGLQGNP 1311 Query: 433 GVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAP 492 G G+ G+ P K G P +A + PG+ PG P Sbjct: 1312 GRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGE---------PGLIGPPGPPGLP 1362 Query: 493 GVG----VAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAA 548 G + G PG+ PG+ PG G+ PG Sbjct: 1363 GPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGL-PGPTGPPGDPGRN---------- 1411 Query: 549 AGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAA 598 GL G G G G PGL G GL G G PG + A Sbjct: 1412 -GL-PGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVA 1459 Score = 90.1 bits (222), Expect = 6e-18 Identities = 154/561 (27%), Positives = 193/561 (34%), Gaps = 101/561 (18%) Query: 205 PGVPLGYPIKAPKLPGGYGLPYTTGK-----LPYGYGPGGVAGAAGKAGYPTGTGVGPQA 259 PG+ G+P P PG G P G+ +P GP G+ G G G+P G Sbjct: 53 PGLE-GHP-GLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFP-----GTPG 105 Query: 260 AAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAG-VGTPAAAAAAAAAAKA 318 A G G G G PG PG PG+ G G G P + + Sbjct: 106 LPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPG-FPGLQGPPGPPGIPGMKGEPGSIIMS 164 Query: 319 AKYGAAAGLVPGGPGFGPGVVGVPG-AGVPG-VGVPGAGIPVVPG-AGIPGAAVPGVVSP 375 + G PG PG PG+ G+PG G+PG +G PG PG G PG PG+ P Sbjct: 165 SLPGPKGN--PGYPG-PPGIQGLPGPTGIPGPIGPPGP-----PGLMGPPGP--PGLPGP 214 Query: 376 EAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPG------------FGVGVGGIPGVA 423 + + K G + G+ G P G PG F G G+PG Sbjct: 215 KGNMGLNFQGPK-GEKGEQGLQGPP-------GPPGQISEQKRPIDVEFQKGDQGLPGDR 266 Query: 424 GVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYG-------------------VGTPAA 464 G PG G+ G G PG + + K K G G P Sbjct: 267 GPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGR 326 Query: 465 AAAKAAAKAAQFGLVPGVGV-APGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG 523 K PG+ + PG G+ +G +GL PG+ G PG+ PG Sbjct: 327 DGEKGQKGDTGPPGPPGLVIPRPGTGIT--IGEKGNIGL-PGLPGEKGERGFPGIQGPPG 383 Query: 524 IGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAG-- 581 + PG AA R G G PG+ + G PGL G PGL G Sbjct: 384 L-PGPPGAAVMGPPGPPGFPGERGQKG-DEGPPGISI-PGPPGLDGQPGAPGLPGPPGPA 440 Query: 582 -----------VPGFGAVPGALAAAKAAKYGAAVPGVLG-------GLGALGGVGIPGGV 623 PG PG+ K + V G G G G G G PG Sbjct: 441 GPHIPPSDEICEPGPPGPPGS-PGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLP 499 Query: 624 VGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIP------PAAAA 677 GP + + Q G G GL G+ G G PG G G P P Sbjct: 500 GLPGPPGSLGFPGQKGEKGQAGATGPKGLPGI-PGAPGAPGFPGSKGEPGDILTFPGMKG 558 Query: 678 KAAKYGVAARPGFGLSPIFPG 698 + G PG P PG Sbjct: 559 DKGELGSPGAPGLPGLPGTPG 579 Score = 65.1 bits (157), Expect = 2e-10 Identities = 115/432 (26%), Positives = 142/432 (32%), Gaps = 66/432 (15%) Query: 296 GIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPGVGVPGA 354 G+ AG+ A + A AA YG + PG G+ G G G PG+ Sbjct: 5 GVSLAAGLFLLALSLWGQPAEAAACYGCS----PGSKCDCSGIKGEKGERGFPGL----- 55 Query: 355 GIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGV 414 G PG +PG PE G R G GIP G PG Sbjct: 56 -------EGHPG--LPGFPGPEGPP---------GPRGQKGDDGIP-------GPPG--- 87 Query: 415 GVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAA 474 GI G G+PG G PG+ G+PG +P Q K G P + Sbjct: 88 -PKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPP 146 Query: 475 QFGLVPGVGVAPG---VGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG----IGPG 527 +PG+ PG + PG PG PG+ PG PG PG +GP Sbjct: 147 GPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPP 206 Query: 528 GVAAAAKSAAKVAAKAQ----------LRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLG 577 G + Q L+ G I + V G+PG Sbjct: 207 GPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDR 266 Query: 578 VGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKA 637 G PG PG K K PG G G G G PG G Sbjct: 267 GPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGR 326 Query: 638 AAKAAQFGLVGAAGLGGL-----GVG-GLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFG 691 + Q G G G GL G G +G G GL G+P + G+ PG Sbjct: 327 DGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFP-GIQGPPGL- 384 Query: 692 LSPIFPGGACLG 703 P PG A +G Sbjct: 385 --PGPPGAAVMG 394 >gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo sapiens] Length = 1688 Score = 169 bits (428), Expect = 8e-42 Identities = 219/741 (29%), Positives = 271/741 (36%), Gaps = 139/741 (18%) Query: 28 GVPGAIPGGVPGGVFYPGAGLGALGG-GALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVT 86 G PG P G+ G PG G G G G GKP K G G Sbjct: 267 GPPG--PPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPG-------------- 310 Query: 87 FPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG----LGVSAAPSVPGAVVPQPGAGVK 142 +PG D G G PG G G + P PG V+P+PG G+ Sbjct: 311 -----IPGLPGDP-----------GYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGIT 354 Query: 143 PGKVPGVGLPGVYPGGVLPGAR----FPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVG 198 G+ +GLPG LPG + FPG+ PG+P G P F G G Sbjct: 355 IGEKGNIGLPG------LPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQK 408 Query: 199 PFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYG-----------YGPGGVAGAAGKA 247 GP PG+ + P PG GLP G P G GP G G+ G Sbjct: 409 GDEGP-PGISIPGPPGLDGQPGAPGLPGPPG--PAGPHIPPSDEICEPGPPGPPGSPGDK 465 Query: 248 GYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPA 307 G GV K F G+ G G+PG+PG +G G Sbjct: 466 GLQGEQGV-------KGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKG 518 Query: 308 AAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-----AGVPG----VGVPGA-GIP 357 A A GA PG PGF PG G PG G+ G +G PGA G+P Sbjct: 519 QAGATGPKGLPGIPGA-----PGAPGF-PGSKGEPGDILTFPGMKGDKGELGSPGAPGLP 572 Query: 358 VVPGAGIPGA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFG--- 413 +PG PG +PG+ P+ + G G+ G+P +G G PGFG Sbjct: 573 GLPGT--PGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPG-NIGPMGPPGFGPPG 629 Query: 414 -VGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYG-------------V 459 VG GI GVAG PG G+PG G PG I+ + + G Sbjct: 630 PVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQP 689 Query: 460 GTPAAAAAKAAAKAAQFGL--VPGVGVAPGVGVAPGVGVAPG-VGL--APGVGVAPGVGV 514 G P +K GL PG PG+ PG PG +GL PG PG Sbjct: 690 GLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKG 749 Query: 515 APGVGVAPGIGPGGV-----AAAAKSAAKVAAKAQLRAAAGLGA-----------GIPGL 558 PG + GP G+ A K GL G PG Sbjct: 750 EPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGP 809 Query: 559 GVGVGVPGLGVGA--GVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGG 616 G+PG+GV G PG+ G PG +PG G VPG G G+ G Sbjct: 810 MGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPG--EKGDPGPPGLDVPGPPGERGSPGI 867 Query: 617 VGIPGGVVGAG----PAAAAAAAKAAAKAAQFGLVGAAG-LGGLGV-GGLGVPGVGGLGG 670 G PG + G P A A+ K + G++G G G LG+ G GVPG+ G G Sbjct: 868 PGAPGPIGPPGSPGLPGKAGASGFPGTK-GEMGMMGPPGPPGPLGIPGRSGVPGLKGDDG 926 Query: 671 I--PPAAAAKAAKYGVAARPG 689 + P + G PG Sbjct: 927 LQGQPGLPGPTGEKGSKGEPG 947 Score = 164 bits (414), Expect = 3e-40 Identities = 216/692 (31%), Positives = 251/692 (36%), Gaps = 109/692 (15%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGG--GALGPGGKPLKPVPGGLAGAGLGAGLG 80 P P G PG P G PG G L G GALGP G P P G G GL Sbjct: 738 PPGPPGFPG--PKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGR---TGLD 792 Query: 81 AFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVVP--QPG 138 P G + P G G G PG+ G+GV P PG P QPG Sbjct: 793 GLPGPK--GDVGPNGQP-------------GPMGPPGLPGIGVQGPPGPPGIPGPIGQPG 837 Query: 139 AGVKPGKVPGVGLPGVYPGGVLPGAR-FPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPG- 196 PG+ G PG+ G PG R PG+ PG P G P PG GA +G PG Sbjct: 838 LHGIPGEKGDPGPPGLDVPGP-PGERGSPGIPGAPG-PIGPPGSPGLPGKAGA-SGFPGT 894 Query: 197 ---VGPFGGPQPGVPLGYPIKA--PKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPT 251 +G G P P PLG P ++ P L G GL G LP GP G G+ G+ G P Sbjct: 895 KGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPG-LP---GPTGEKGSKGEPGLP- 949 Query: 252 GTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGV-GTPAAAA 310 GP G +L G G PG+PG IPG+ G G G P Sbjct: 950 ----GPP-------------GPMDPNLLGSKGEKGEPGLPG-IPGVSGPKGYQGLPGDPG 991 Query: 311 AAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIPGAAVP 370 + + G P GP PG+ G PG +G PG + G PG Sbjct: 992 QPGLSGQPGLPG------PPGPKGNPGLPGQPGL----IGPPGLK-GTIGDMGFPGPQ-- 1038 Query: 371 GVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGG 430 GV P + + G G G P G+ + G PG G G PG+ G PG G Sbjct: 1039 GVEGPPGPSGVPGQPGSPGLPGQKGDKGDP--GISSIGLPGLP-GPKGEPGLPGYPGNPG 1095 Query: 431 VPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGV 490 + G G PG+ P A GTP K + +PG G G Sbjct: 1096 IKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGG 1155 Query: 491 APGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAG 550 PG PG PG PG G PG G G Sbjct: 1156 HPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPG---------------------- 1193 Query: 551 LGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALA-AAKAAKYGAAVPGVLG 609 G+PGL G GL G PGL G PGF PG G A+ G G Sbjct: 1194 -PPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKG 1252 Query: 610 GLGALGGVGIPG--GVVG-AGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVG 666 G G G PG G+ G GP + G G GL GL G G PG+ Sbjct: 1253 NPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGL-KGDQGPPGLQ 1311 Query: 667 GLGGIPPAAAAKAAKYGVAARPGFGLSPIFPG 698 G G P G+ PG P FPG Sbjct: 1312 GNPGRP-------GLNGMKGDPGLPGVPGFPG 1336 Score = 138 bits (348), Expect = 2e-32 Identities = 208/729 (28%), Positives = 263/729 (36%), Gaps = 120/729 (16%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGA-GLGALGG--GALGPGGKPLKPVPG--GLAGAGLGA 77 P P G+ G P G+PG +PG GL + G GA GP G +PG G G Sbjct: 85 PPGPKGIRG--PPGLPG---FPGTPGLPGMPGHDGAPGPQG-----IPGCNGTKGERGFP 134 Query: 78 GLGAFPAVTFPGAL--VPGGVADAAAAYKAAKAGA----------GLGGVPGVGGLGVSA 125 G FP + P +PG + + ++ G G+ G+PG G+ Sbjct: 135 GSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPI 194 Query: 126 APSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAP 185 P P ++ PG PG +GL P G G P P G + K P Sbjct: 195 GPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQG----PPGPPGQISEQKRP 250 Query: 186 GVGGAF----AGIPG-VGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGK--LPYGYGPG 238 + F G+PG GP G P P G P G G P GK G Sbjct: 251 -IDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQP 309 Query: 239 GVAGAAGKAGYPTGTG----VGPQAAAAAAAKAAAKFGAGAAGVLPG-VGGAGVPGVPG- 292 G+ G G GYP G G + G+ G G G+PG+PG Sbjct: 310 GIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGE 369 Query: 293 ----AIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AGVP 347 PGI G G+ P AA PG PGF PG G G G P Sbjct: 370 KGERGFPGIQGPPGLPGPPGAAVMGP--------------PGPPGF-PGERGQKGDEGPP 414 Query: 348 GVGVPGA----GIPVVPG-AGIPGAAVPGVVSPEAAAKAA-----AKAAKYGARPGVGVG 397 G+ +PG G P PG G PG A P + + + G + GV Sbjct: 415 GISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVK 474 Query: 398 GIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKY 457 G G F G G+ G PG G+PG+ G PG G PG + A A K Sbjct: 475 G----DKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPG---QKGEKGQAGATGPKG 527 Query: 458 GVGTPAAAAAKAAAKAAQFGLVPGVGVAPG-VGVAPGVGVAPGVGLAPGVGVAPGVGVAP 516 G P A A PG PG + PG+ G +PG PG+ P Sbjct: 528 LPGIPGAPGAPG---------FPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTP 578 Query: 517 GVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRAAAGLG-AGIPGLGVGVGVPGLGV--GAG 572 G PG+ GP G + K + G G+PG +G PG G G Sbjct: 579 GQDGLPGLPGPKG------EPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVG 632 Query: 573 VPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAA 632 G+ AG PG +PG PG+ G G G VG+PG G Sbjct: 633 EKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLP 692 Query: 633 AAAKAAAKAAQFGLVGAAGLGGL-GVGGLGVPGVGGLGGI--PPAAAAKAAKYGVAARPG 689 G+ G+ G G+ G+G G PG G GI PP A + G+ PG Sbjct: 693 ------------GIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPG 740 Query: 690 FGLSPIFPG 698 P FPG Sbjct: 741 ---PPGFPG 746 Score = 137 bits (344), Expect = 4e-32 Identities = 199/651 (30%), Positives = 237/651 (36%), Gaps = 119/651 (18%) Query: 23 PSRPG-----GVPGAI-PGGVPGGVFYPG-AGLGALGG-----GALGPGGKP-------L 63 P PG G+PGA P G PG PG AG G G +GP G P Sbjct: 856 PGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGR 915 Query: 64 KPVPG-----GLAGA-GLGAGLGAFPAVTFPGALVPGGVADA-AAAYKAAKAGAGLGGVP 116 VPG GL G GL G + PG P G D K K GL G+P Sbjct: 916 SGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIP 975 Query: 117 GVGG-LGVSAAPSVPG--AVVPQPGAGVKPGKVPGVGLPGVYPG--------GVLPGARF 165 GV G G P PG + QPG PG GLPG PG G + F Sbjct: 976 GVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPG-QPGLIGPPGLKGTIGDMGF 1034 Query: 166 PGVGVLPGVPTGAGV--KPKAPGVGGAFA--GIPGVGPFGGPQPGVPLGYPIKAPKLPGG 221 PG + G P +GV +P +PG+ G G PG+ G P P G P P PG Sbjct: 1035 PGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEP-GLPGYPGN 1093 Query: 222 YGLPYTTGK--LPYGYGPGGVAGAAGKAGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGV 278 G+ + G LP G G G G G+P G GP+ + G G Sbjct: 1094 PGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNP------GLPGE 1147 Query: 279 LPGVGGAGVPGVPGAIPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFG-P 336 VGG G PG PG PG G G G P A PG PGFG P Sbjct: 1148 PGPVGGGGHPGQPGP-PGEKGKPGQDGIPGPAGQKGE--------------PGQPGFGNP 1192 Query: 337 GVVGVPG-------AGVPGV----GVPGA-------GIPVVPGA-GIPGAAVPGVVSPEA 377 G G+PG G+PG+ G+PG G P V G G PG+ P + P+ Sbjct: 1193 GPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKG 1252 Query: 378 AAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFG--VGVGGIPGVAGVPGVGGVPGVG 435 + G + G G P G PG G G G PG G+PG+ G+ G Sbjct: 1253 NPGPQGPPGRPGFQGLPGPEGPP-------GLPGNGGIKGEKGNPGQPGLPGLPGLKGDQ 1305 Query: 436 GVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVA---PGVGVAP 492 G PG+ +P K G P K + VPG PG+ P Sbjct: 1306 GPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSG------VPGSAGPEGEPGLIGPP 1359 Query: 493 GVGVAPGVG----LAPGVGVAPGVGVAPGVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRA 547 G PG + G PG+ PG+ PG GP G+ Sbjct: 1360 GPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRN----- 1414 Query: 548 AAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAA 598 GL G G G G PGL G GL G G PG + A Sbjct: 1415 --GL-PGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVA 1462 Score = 90.1 bits (222), Expect = 6e-18 Identities = 154/561 (27%), Positives = 193/561 (34%), Gaps = 101/561 (18%) Query: 205 PGVPLGYPIKAPKLPGGYGLPYTTGK-----LPYGYGPGGVAGAAGKAGYPTGTGVGPQA 259 PG+ G+P P PG G P G+ +P GP G+ G G G+P G Sbjct: 53 PGLE-GHP-GLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFP-----GTPG 105 Query: 260 AAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAG-VGTPAAAAAAAAAAKA 318 A G G G G PG PG PG+ G G G P + + Sbjct: 106 LPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPG-FPGLQGPPGPPGIPGMKGEPGSIIMS 164 Query: 319 AKYGAAAGLVPGGPGFGPGVVGVPG-AGVPG-VGVPGAGIPVVPG-AGIPGAAVPGVVSP 375 + G PG PG PG+ G+PG G+PG +G PG PG G PG PG+ P Sbjct: 165 SLPGPKGN--PGYPG-PPGIQGLPGPTGIPGPIGPPGP-----PGLMGPPGP--PGLPGP 214 Query: 376 EAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPG------------FGVGVGGIPGVA 423 + + K G + G+ G P G PG F G G+PG Sbjct: 215 KGNMGLNFQGPK-GEKGEQGLQGPP-------GPPGQISEQKRPIDVEFQKGDQGLPGDR 266 Query: 424 GVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYG-------------------VGTPAA 464 G PG G+ G G PG + + K K G G P Sbjct: 267 GPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGR 326 Query: 465 AAAKAAAKAAQFGLVPGVGV-APGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG 523 K PG+ + PG G+ +G +GL PG+ G PG+ PG Sbjct: 327 DGEKGQKGDTGPPGPPGLVIPRPGTGIT--IGEKGNIGL-PGLPGEKGERGFPGIQGPPG 383 Query: 524 IGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAG-- 581 + PG AA R G G PG+ + G PGL G PGL G Sbjct: 384 L-PGPPGAAVMGPPGPPGFPGERGQKG-DEGPPGISI-PGPPGLDGQPGAPGLPGPPGPA 440 Query: 582 -----------VPGFGAVPGALAAAKAAKYGAAVPGVLG-------GLGALGGVGIPGGV 623 PG PG+ K + V G G G G G G PG Sbjct: 441 GPHIPPSDEICEPGPPGPPGS-PGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLP 499 Query: 624 VGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIP------PAAAA 677 GP + + Q G G GL G+ G G PG G G P P Sbjct: 500 GLPGPPGSLGFPGQKGEKGQAGATGPKGLPGI-PGAPGAPGFPGSKGEPGDILTFPGMKG 558 Query: 678 KAAKYGVAARPGFGLSPIFPG 698 + G PG P PG Sbjct: 559 DKGELGSPGAPGLPGLPGTPG 579 Score = 65.1 bits (157), Expect = 2e-10 Identities = 115/432 (26%), Positives = 142/432 (32%), Gaps = 66/432 (15%) Query: 296 GIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPGVGVPGA 354 G+ AG+ A + A AA YG + PG G+ G G G PG+ Sbjct: 5 GVSLAAGLFLLALSLWGQPAEAAACYGCS----PGSKCDCSGIKGEKGERGFPGL----- 55 Query: 355 GIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGV 414 G PG +PG PE G R G GIP G PG Sbjct: 56 -------EGHPG--LPGFPGPEGPP---------GPRGQKGDDGIP-------GPPG--- 87 Query: 415 GVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAA 474 GI G G+PG G PG+ G+PG +P Q K G P + Sbjct: 88 -PKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPP 146 Query: 475 QFGLVPGVGVAPG---VGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG----IGPG 527 +PG+ PG + PG PG PG+ PG PG PG +GP Sbjct: 147 GPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPP 206 Query: 528 GVAAAAKSAAKVAAKAQ----------LRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLG 577 G + Q L+ G I + V G+PG Sbjct: 207 GPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDR 266 Query: 578 VGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKA 637 G PG PG K K PG G G G G PG G Sbjct: 267 GPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGR 326 Query: 638 AAKAAQFGLVGAAGLGGL-----GVG-GLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFG 691 + Q G G G GL G G +G G GL G+P + G+ PG Sbjct: 327 DGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFP-GIQGPPGL- 384 Query: 692 LSPIFPGGACLG 703 P PG A +G Sbjct: 385 --PGPPGAAVMG 394 >gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo sapiens] Length = 1691 Score = 167 bits (424), Expect = 2e-41 Identities = 223/739 (30%), Positives = 284/739 (38%), Gaps = 107/739 (14%) Query: 28 GVPGAIPG--GVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAV 85 G+PG +PG G PG PG GL L G PG K +PG GL G Sbjct: 602 GLPG-LPGEKGHPGPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQ---QGLPGSKGITLPC 657 Query: 86 TFPGALVPGGVADAAAAYKAAKAGAGLGGVPGV-GGLGVSAAPSVPGAV-VPQ-PGAGVK 142 PG+ P G + K GL G PG G G P PG V +P+ PG Sbjct: 658 IIPGSYGPSGFP-GTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGF--- 713 Query: 143 PGKVPGVGLPGVYPGGVLPGAR-FPGVGVLPGVP-----TGA--GVKPKAPGVGG----- 189 PG GLPG +PG LPG PG+ PG+P TG G + APG G Sbjct: 714 PGPRGEKGLPG-FPG--LPGKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLT 770 Query: 190 ------AFAGIPGV-GPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAG 242 +G+PG+ G G P P G +P PG G P T G GP G+ G Sbjct: 771 GHKGFLGDSGLPGLKGVHGKPGLLGPKGER-GSPGTPGQVGQPGTPGSS----GPYGIKG 825 Query: 243 AAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAG 302 +G G P G+ + K + G G + G G+ G+PG PG+ G+ G Sbjct: 826 KSGLPGAPGFPGI-----SGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGN-PGLVGLKG 879 Query: 303 V-GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA----GVPG----VGVPG 353 G+P A A + + G+ G V G PG PG+ G+PG G+PG +G G Sbjct: 880 SPGSPGVAGLPALSGPKGEKGSV-GFV-GFPGI-PGLPGIPGTRGLKGIPGSTGKMGPSG 936 Query: 354 -AGIPVVPG-AGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIP----------- 400 AG P G G PG G+ SP G++ G G P Sbjct: 937 RAGTPGEKGDRGNPGPV--GIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGR 994 Query: 401 --TYGV-GAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKY 457 G+ GA G PG GV G PG G G+ G+PG+ G G+ P + ++ + Sbjct: 995 PGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITGFPGMPGESGSQGIRG 1054 Query: 458 GVGTPAAAAAKAA----AKAAQFGLVPGVGVAPGVGVAPGV----GVAPGVGLAPGVGVA 509 G P A+ + + PG PG G G+ +G G Sbjct: 1055 SPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNKGED 1114 Query: 510 PGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGA----------GIPGLG 559 VGV+ VG+ G GVA + A LG+ G PGL Sbjct: 1115 GKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLH 1174 Query: 560 VGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGI 619 G+PG G PG + GVPG +PG G PG G G G G Sbjct: 1175 GLNGLPGTKGTHGTPGPSI-TGVPGPAGLPGPKGEKGYPGIGIGAPGKPGLRGQKGDRGF 1233 Query: 620 PGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKA 679 PG AG A + + A Q G G GL G G PG G PP + Sbjct: 1234 PGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLD----GERGRPGPAG----PPGPPGPS 1285 Query: 680 AKYGVAARPGFGLSPIFPG 698 + G PGF P PG Sbjct: 1286 SNQGDTGDPGF---PGIPG 1301 Score = 142 bits (358), Expect = 1e-33 Identities = 228/803 (28%), Positives = 291/803 (36%), Gaps = 175/803 (21%) Query: 20 ILHPSRPGGVPGAI-PGGVPGGVFYPG----------AGLGALGG-------GALGPGGK 61 I P G PGA+ P G PG PG GLG G G GP G Sbjct: 182 ITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGP 241 Query: 62 P-------LKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGG 114 P P G G+ G FP ++ P PG K K G+ G Sbjct: 242 PPSTGELEFMGFPKGKKGSKGEPGPKGFPGISGP----PGFPGLGTTGEKGEKGEKGIPG 297 Query: 115 VPG----VGGLGVSAAPSVPG--AVVPQPG----AGVKPGKVPGVGLPGV-----YPGGV 159 +PG +G GV P G + PG G++ G+ +GLPG G V Sbjct: 298 LPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGIE-GQKGDIGLPGPDVFIDIDGAV 356 Query: 160 LPG-ARFPGVGVLPGVPTGAGVKP-KAP-GVGG--AFAGIPG-VGPFGGP----QPGVPL 209 + G PGV LPG+ G++ + P GV G A +G+PG +GP G P G P Sbjct: 357 ISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPG 416 Query: 210 GYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAG-----------KAGYPTGTG-VGP 257 I A LPG GLP GP G G ++G+P G GP Sbjct: 417 RTTIGAAGLPGRDGLP----------GPPGPPGPPSPEFETETLHNKESGFPGLRGEQGP 466 Query: 258 QA-AAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG-----AIPGIGGIAG--------- 302 + K + F A GV P G G PG PG +PG+ G G Sbjct: 467 KGNLGLKGIKGDSGFCACDGGV-PNTGPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQG 525 Query: 303 -VGTPAAAAAAAAAAKAAKYG-AAAGLVPGGPGFG--------PGVVGVPGA-GVPGV-G 350 G P + K G + G PG GV+G PG GVPG+ G Sbjct: 526 PAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPG 585 Query: 351 VPG------------AGIPVVPG-------AGIPGAAVPGVVSPEAAAKAAAKAAKYGAR 391 +PG G+P +PG G+PG +PG+ P K G + Sbjct: 586 LPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQQ 645 Query: 392 PGVGVGGI-----------PTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGV 440 G GI P+ G GFPG G G+PG G PG G G G PG+ Sbjct: 646 GLPGSKGITLPCIIPGSYGPSGFPGTPGFPG-PKGSRGLPGTPGQPGSSGSKGEPGSPGL 704 Query: 441 GISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGV 500 PE + K G P +PG PG+ +PG+ + G Sbjct: 705 VHLPELPGFPGPRGEKGLPGFPG---------------LPGKDGLPGMIGSPGLPGSKGA 749 Query: 501 --GLAPGVGVAPGVGVAPGVGVAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPG 557 + APG G+ G +G G+ V K L G G PG Sbjct: 750 TGDIFGAENGAPGEQGLQGLTGHKGFLGDSGL----PGLKGVHGKPGLLGPKG-ERGSPG 804 Query: 558 LGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGAL-------AAAKAAKYGAAV----PG 606 VG PG +G G+ +G+PG PG K G+ V PG Sbjct: 805 TPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPG 864 Query: 607 VLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVG 666 + G G G VG+ G G A A + + G VG G+ GL G+PG Sbjct: 865 LKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLP----GIPGTR 920 Query: 667 GLGGIPPAAAAKAAKYGVAARPG 689 GL GI P + K G A PG Sbjct: 921 GLKGI-PGSTGKMGPSGRAGTPG 942 Score = 140 bits (354), Expect = 3e-33 Identities = 227/768 (29%), Positives = 288/768 (37%), Gaps = 133/768 (17%) Query: 23 PSRPG--GVPGAI-----PG--GVPGGVF-----YPGA-GLGALGG--GALGPGGKP-LK 64 P PG G+PG I PG G G +F PG GL L G G LG G P LK Sbjct: 726 PGLPGKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLK 785 Query: 65 PVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGL--- 121 V G GL G + PG + G ++ Y K +GL G PG G+ Sbjct: 786 GVHGK---PGLLGPKGERGSPGTPGQVGQPGTPGSSGPY-GIKGKSGLPGAPGFPGISGH 841 Query: 122 ----GVSAAPSVPGAVVPQPGAGVK--PGKVPGVGL------PGVYPGGVLPGAR----- 164 G PG++V + G+K PG VGL PGV L G + Sbjct: 842 PGKKGTRGKKGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGS 901 Query: 165 -----FPGVGVLPGVPTGAGVKPKAPGVGGAF-----AGIPGV-------GPFGGPQPGV 207 FPG+ LPG+P G+K PG G AG PG GP G P P Sbjct: 902 VGFVGFPGIPGLPGIPGTRGLKG-IPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRR 960 Query: 208 PLGYP-IKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAK 266 P+ +K K G G + G P G G AG G G P G+ P + K Sbjct: 961 PMSNLWLKGDK--GSQGSAGSNG-FPGPRGDKGEAGRPGPPGLPGAPGL-PGIIKGVSGK 1016 Query: 267 AAAKFGAGAAGVLPGV-GGAGVPGVPGAIPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAA 324 G G LPG+ G +G+ G PG +PG G G+ G+P A+ G Sbjct: 1017 PGPPGFMGIRG-LPGLKGSSGITGFPG-MPGESGSQGIRGSPGLPGASGLPGLKGDNGQT 1074 Query: 325 AGLVPG-GPGFGPGVVGVPGAG-----VPGVGVPG-----AGIPVVPGAGIPGA-AVPGV 372 + GP PG G G + +G PG + V G+PGA PGV Sbjct: 1075 VEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGV 1134 Query: 373 VSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGF-GV-GVGGIPG--------- 421 + GA +G G+ +G GFPGF G+ G+ G+PG Sbjct: 1135 AGMRGEPGLPGSSGHQGAIGPLGSPGL----IGPKGFPGFPGLHGLNGLPGTKGTHGTPG 1190 Query: 422 --VAGVPGVGGVPGVGG---VPGVGISPEAQAAAAAKAAKYG-------VGTPAAAAAKA 469 + GVPG G+PG G PG+GI + + G G P A Sbjct: 1191 PSITGVPGPAGLPGPKGEKGYPGIGIGAPGKPGLRGQKGDRGFPGLQGPAGLPGAPGISL 1250 Query: 470 AAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI----G 525 + A PG G PG PG PG G PG PG G Sbjct: 1251 PSLIAGQPGDPGRPGLDGERGRPGPAGPPG---PPGPSSNQGDTGDPGFPGIPGPKGPKG 1307 Query: 526 PGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGF 585 G+ + ++ K +R G G PG VG PG G+ G G G Sbjct: 1308 DQGIPGFSGLPGELGLKG-MRGEPGF-MGTPGK---VGPPGDPGFPGMKGKAGPRGSSGL 1362 Query: 586 GAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFG 645 PG A+A + VP G LG G GIPG + P A +K G Sbjct: 1363 QGDPGQTPTAEAVQ----VPP--GPLGLPGIDGIPG--LTGDPGAQGPVGLQGSKGLP-G 1413 Query: 646 LVGAAGLGGL--GVGGLGVPGVGGLGGIP--PAAAAKAAKYGVAARPG 689 + G G GL G LG PG+ GL G P A + +G+ PG Sbjct: 1414 IPGKDGPSGLPGPPGALGDPGLPGLQGPPGFEGAPGQQGPFGMPGMPG 1461 Score = 138 bits (347), Expect = 2e-32 Identities = 209/707 (29%), Positives = 253/707 (35%), Gaps = 155/707 (21%) Query: 1 MAGLTAAAPRPGVLLLLLSILHPSRPG-----GVPGAI-PGGVPGGVFYPGA-GLGALGG 53 + GL +PG+L P PG G PG+ P G+ G PGA G + G Sbjct: 781 LPGLKGVHGKPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISG 840 Query: 54 GALGPGGKPLKPVPGGLAGAGLGAGLGAFPA----VTFPGALVPGGVAD--AAAAYKAAK 107 G + K PG + GL GL P V G+ GVA A + K K Sbjct: 841 HPGKKGTRGKKGPPGSIVKKGL-PGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEK 899 Query: 108 AGAGLGGVPGVGGL-------GVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGV- 159 G G PG+ GL G+ P G + P AG PG+ G PG P G+ Sbjct: 900 GSVGFVGFPGIPGLPGIPGTRGLKGIPGSTGKMGPSGRAGT-PGEKGDRGNPG--PVGIP 956 Query: 160 -------------------------LPGAR-------------FPGVGVLPGVPTGAGVK 181 PG R PG LPG+ G K Sbjct: 957 SPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGK 1016 Query: 182 PKAPGVGGAFAGIPGV----GPFGGP-QPGVPLGYPIK-APKLPGGYGLPYTTGKL---- 231 P PG G G+PG+ G G P PG I+ +P LPG GLP G Sbjct: 1017 PGPPGFMG-IRGLPGLKGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTV 1075 Query: 232 -------PYGY-GPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVG 283 P G G G G G+ G G + G A PGV Sbjct: 1076 EISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVA 1135 Query: 284 GA-GVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGF----GPGV 338 G G PG+PG+ G I +G+P +G +PG G GP + Sbjct: 1136 GMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLNG--LPGTKGTHGTPGPSI 1193 Query: 339 VGVPG-AGVPGV----GVPGAGI--PVVPG----------------AGIPGAAVPGVVSP 375 GVPG AG+PG G PG GI P PG AG+PGA PG+ P Sbjct: 1194 TGVPGPAGLPGPKGEKGYPGIGIGAPGKPGLRGQKGDRGFPGLQGPAGLPGA--PGISLP 1251 Query: 376 EAAAKAAAKAAKYG-----ARPG-VGVGGIP--TYGVGAGGFPGFGVGVGGIPGVAGVPG 427 A + G RPG G G P + G G PGF GIPG G G Sbjct: 1252 SLIAGQPGDPGRPGLDGERGRPGPAGPPGPPGPSSNQGDTGDPGFP----GIPGPKGPKG 1307 Query: 428 VGGVPGVGGVPG-VGISP-EAQAAAAAKAAKYGV-GTPAAAAAKA-AAKAAQFGLVPGVG 483 G+PG G+PG +G+ + K G G P K A GL G Sbjct: 1308 DQGIPGFSGLPGELGLKGMRGEPGFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQGDPG 1367 Query: 484 VAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKA 543 P A V V PG PG+ PG+ PG GP G Sbjct: 1368 QTP---TAEAVQVPPGPLGLPGIDGIPGLTGDPGAQ-----GPVG--------------- 1404 Query: 544 QLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPG 590 L+ + GL GIPG G+PG G PGL G PGF PG Sbjct: 1405 -LQGSKGL-PGIPGKDGPSGLPGPPGALGDPGLPGLQGPPGFEGAPG 1449 Score = 129 bits (325), Expect = 7e-30 Identities = 219/819 (26%), Positives = 292/819 (35%), Gaps = 205/819 (25%) Query: 54 GALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLG 113 G GP G P G G+ +GL FPG L P G K G Sbjct: 50 GRPGPIGIQGPTGPQGFTGSTGLSGLKGERG--FPGLLGPYG----------PKGDKGPM 97 Query: 114 GVPGVGGLGVSAAPSVPGAVVPQ--PGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVL 171 GVPG LG++ P PG P+ PG G VG PG P G +PG+ Sbjct: 98 GVPGF--LGINGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPG--PDG------YPGLLGP 147 Query: 172 PGVPTGAGVK----------------PKAPGVGG-----AFAGIPG-VGPFGGP----QP 205 PG+P G K P PG+ G G PG VGP G P P Sbjct: 148 PGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPP 207 Query: 206 GVP--------LGYPIKAPK-------LPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYP 250 G P +G + K LPG G P +TG+L + P G G+ G+ G Sbjct: 208 GPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPK 267 Query: 251 TGTGVGPQAAAAAAAKAAAKFGAGAAGV--LPG----VGGAGVPGVPG--------AIPG 296 G+ K G G+ LPG +G GV G PG PG Sbjct: 268 GFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPG 327 Query: 297 IGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG------------- 343 + G G+ A ++ G PG PGV G+PG Sbjct: 328 LNGFQGIEGQKGDIGLPGPDVFIDIDGA--VISGNPG-DPGVPGLPGLKGDEGIQGLRGP 384 Query: 344 AGVPGV----GVPGA----GIPVVPG------------AGIPG-------AAVPGVVSPE 376 +GVPG+ GVPGA G P + G AG+PG PG SPE Sbjct: 385 SGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPE 444 Query: 377 AAAKA--------AAKAAKYGARPGVGV-------------GGIPTYG-VGAGGFPG-FG 413 + + G + +G+ GG+P G G G PG +G Sbjct: 445 FETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWG 504 Query: 414 -VGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAK 472 +G+ G+ G G G GG G G PG+ + P + K + + T Sbjct: 505 LIGLPGLKGARGDRGSGGAQGPAGAPGL-VGPLGPSGPKGKKGEPILSTIQGMPGDRGDS 563 Query: 473 AAQ--FGLV--PGVGVAPGVGVAPGVGVAPGVGL--------APGVGVAPGVGVAPGVGV 520 +Q G++ PG PG+ PG+ G G PG PG PG G+ Sbjct: 564 GSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPGLPGNGL 623 Query: 521 APGI-GPGGVAAAAKSAAKVAAKAQLRAAAG--LGAGIPGLGVGVGVPGLGVGAGVPGLG 577 PG+ GP G+ K + + L + G L IPG G PG G PG Sbjct: 624 -PGLPGPRGL-PGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGT---PGFPGPK 678 Query: 578 VGAGVPGFGAVPGALAA-----AKAAKYGAAVPGVLGGLGALGGVGIPG--------GVV 624 G+PG PG+ + + + +PG G G G G PG G++ Sbjct: 679 GSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMI 738 Query: 625 GAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLG-----VGGLGVPGVGGLGGIP------- 672 G+ + A A+ G G GL GL +G G+PG+ G+ G P Sbjct: 739 GSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKG 798 Query: 673 -------------PAAAAKAAKYGVAARPGFGLSPIFPG 698 P + YG+ + G +P FPG Sbjct: 799 ERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPG 837 Score = 120 bits (302), Expect = 3e-27 Identities = 164/535 (30%), Positives = 211/535 (39%), Gaps = 99/535 (18%) Query: 28 GVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVT- 86 G PG P G+PG PG G G KP P G G GL +T Sbjct: 993 GRPG--PPGLPGAPGLPGIIKGVSG-----------KPGPPGFMGIRGLPGLKGSSGITG 1039 Query: 87 FPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG-----LGVSAAPSVPGAVVPQPG-AG 140 FPG +PG + + + G G+PG+ G + +S +P G QPG +G Sbjct: 1040 FPG--MPG--ESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKG----QPGESG 1091 Query: 141 VK-----PGKVPGVGLPGVYPG----GVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAF 191 K G + +G PG GV PG PG P AG++ + PG+ G+ Sbjct: 1092 FKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGA---PGFPGVAGMRGE-PGLPGSS 1147 Query: 192 AGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTG-------KLPYGYGPGGVAGAA 244 +GP G P P G+P P L G GLP T G + GP G+ G Sbjct: 1148 GHQGAIGPLGSPGLIGPKGFP-GFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPK 1206 Query: 245 GKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGG-AGVPGVPG-AIPGIGGIAG 302 G+ GYP G G+G A K + G G PG+ G AG+PG PG ++P + IAG Sbjct: 1207 GEKGYP-GIGIG------APGKPGLRGQKGDRG-FPGLQGPAGLPGAPGISLPSL--IAG 1256 Query: 303 VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AGVPGV-------GVPG- 353 P + + G A P GP G G PG G+PG G+PG Sbjct: 1257 --QPGDPGRPGLDGERGRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGF 1314 Query: 354 AGIPVVPGA----GIPG-AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGG 408 +G+P G G PG PG V P K G R G+ G P G Sbjct: 1315 SGLPGELGLKGMRGEPGFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQGDP-------G 1367 Query: 409 FPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAK 468 V PG G+PG+ G+PG+ G PG AQ + +K G P Sbjct: 1368 QTPTAEAVQVPPGPLGLPGIDGIPGLTGDPG------AQGPVGLQGSKGLPGIP------ 1415 Query: 469 AAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG 523 K GL PG A G PG+ PG APG G+ PG + G Sbjct: 1416 --GKDGPSGL-PGPPGALGDPGLPGLQGPPGFEGAPGQQGPFGMPGMPGQSMRVG 1467 Score = 89.0 bits (219), Expect = 1e-17 Identities = 154/550 (28%), Positives = 192/550 (34%), Gaps = 110/550 (20%) Query: 198 GPFGGPQPGVPLGYPIKA--PKLPGGYGLPYTTGKLPYG----YGPGGVAGAAGKAGYPT 251 GP G P P G+ L G G P G PYG GP GV G G G P Sbjct: 53 GPIGIQGPTGPQGFTGSTGLSGLKGERGFPGLLG--PYGPKGDKGPMGVPGFLGINGIPG 110 Query: 252 GTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAI--PGIGGIAGV-GTPA 307 G GP+ G G VG G G PG + PG+ G G G P Sbjct: 111 HPGQPGPRGPPGLD---------GCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPV 161 Query: 308 AAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPGVGVPGAGIPVVPGA--GI 364 A + K G PG PG+ G+ G G PG PGA P P G Sbjct: 162 LAPGSFKGMK------------GDPGL-PGLDGITGPQGAPGF--PGAVGPAGPPGLQGP 206 Query: 365 PGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGI--PTYGVGAGGFPGFGVGVGGIPGV 422 PG PG + P+ + K G + VG+ G P G F GF G G G Sbjct: 207 PGP--PGPLGPDGNMGLGFQGEK-GVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGE 263 Query: 423 AGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGV 482 G G G+ G G PG+G + E K K G P + + PG Sbjct: 264 PGPKGFPGISGPPGFPGLGTTGE-------KGEKGEKGIPGLPGPRGPMGSEGVQGPPGQ 316 Query: 483 GVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGV---APGVGVAPGIGPGGVAAAAKSAAKV 539 G PG+ G+ G PG V G ++ G GV Sbjct: 317 QGKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVP--------- 367 Query: 540 AAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAK 599 G+PGL G+ GL +GVPGL +GVPG P K + Sbjct: 368 --------------GLPGLKGDEGIQGLRGPSGVPGLPALSGVPG-ALGPQGFPGLKGDQ 412 Query: 600 YGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAA-AKAAQF-GLVGAAG-LGGLG 656 G +G G G G+PG GP + + K + F GL G G G LG Sbjct: 413 -GNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLG 471 Query: 657 VGGL----------------------GVPGVGGLGGIPPAAAAKAAK-----YGVAARPG 689 + G+ G PG GL G+P A+ + G A PG Sbjct: 472 LKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPG 531 Query: 690 FGLSPIFPGG 699 + P+ P G Sbjct: 532 L-VGPLGPSG 540 >gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo sapiens] Length = 1690 Score = 167 bits (424), Expect = 2e-41 Identities = 223/739 (30%), Positives = 284/739 (38%), Gaps = 107/739 (14%) Query: 28 GVPGAIPG--GVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAV 85 G+PG +PG G PG PG GL L G PG K +PG GL G Sbjct: 601 GLPG-LPGEKGHPGPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQ---QGLPGSKGITLPC 656 Query: 86 TFPGALVPGGVADAAAAYKAAKAGAGLGGVPGV-GGLGVSAAPSVPGAV-VPQ-PGAGVK 142 PG+ P G + K GL G PG G G P PG V +P+ PG Sbjct: 657 IIPGSYGPSGFP-GTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGF--- 712 Query: 143 PGKVPGVGLPGVYPGGVLPGAR-FPGVGVLPGVP-----TGA--GVKPKAPGVGG----- 189 PG GLPG +PG LPG PG+ PG+P TG G + APG G Sbjct: 713 PGPRGEKGLPG-FPG--LPGKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLT 769 Query: 190 ------AFAGIPGV-GPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAG 242 +G+PG+ G G P P G +P PG G P T G GP G+ G Sbjct: 770 GHKGFLGDSGLPGLKGVHGKPGLLGPKGER-GSPGTPGQVGQPGTPGSS----GPYGIKG 824 Query: 243 AAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAG 302 +G G P G+ + K + G G + G G+ G+PG PG+ G+ G Sbjct: 825 KSGLPGAPGFPGI-----SGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGN-PGLVGLKG 878 Query: 303 V-GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA----GVPG----VGVPG 353 G+P A A + + G+ G V G PG PG+ G+PG G+PG +G G Sbjct: 879 SPGSPGVAGLPALSGPKGEKGSV-GFV-GFPGI-PGLPGIPGTRGLKGIPGSTGKMGPSG 935 Query: 354 -AGIPVVPG-AGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIP----------- 400 AG P G G PG G+ SP G++ G G P Sbjct: 936 RAGTPGEKGDRGNPGPV--GIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGR 993 Query: 401 --TYGV-GAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKY 457 G+ GA G PG GV G PG G G+ G+PG+ G G+ P + ++ + Sbjct: 994 PGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITGFPGMPGESGSQGIRG 1053 Query: 458 GVGTPAAAAAKAA----AKAAQFGLVPGVGVAPGVGVAPGV----GVAPGVGLAPGVGVA 509 G P A+ + + PG PG G G+ +G G Sbjct: 1054 SPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNKGED 1113 Query: 510 PGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGA----------GIPGLG 559 VGV+ VG+ G GVA + A LG+ G PGL Sbjct: 1114 GKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLH 1173 Query: 560 VGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGI 619 G+PG G PG + GVPG +PG G PG G G G G Sbjct: 1174 GLNGLPGTKGTHGTPGPSI-TGVPGPAGLPGPKGEKGYPGIGIGAPGKPGLRGQKGDRGF 1232 Query: 620 PGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKA 679 PG AG A + + A Q G G GL G G PG G PP + Sbjct: 1233 PGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLD----GERGRPGPAG----PPGPPGPS 1284 Query: 680 AKYGVAARPGFGLSPIFPG 698 + G PGF P PG Sbjct: 1285 SNQGDTGDPGF---PGIPG 1300 Score = 142 bits (358), Expect = 1e-33 Identities = 228/803 (28%), Positives = 291/803 (36%), Gaps = 175/803 (21%) Query: 20 ILHPSRPGGVPGAI-PGGVPGGVFYPG----------AGLGALGG-------GALGPGGK 61 I P G PGA+ P G PG PG GLG G G GP G Sbjct: 181 ITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGP 240 Query: 62 P-------LKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGG 114 P P G G+ G FP ++ P PG K K G+ G Sbjct: 241 PPSTGELEFMGFPKGKKGSKGEPGPKGFPGISGP----PGFPGLGTTGEKGEKGEKGIPG 296 Query: 115 VPG----VGGLGVSAAPSVPG--AVVPQPG----AGVKPGKVPGVGLPGV-----YPGGV 159 +PG +G GV P G + PG G++ G+ +GLPG G V Sbjct: 297 LPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGIE-GQKGDIGLPGPDVFIDIDGAV 355 Query: 160 LPG-ARFPGVGVLPGVPTGAGVKP-KAP-GVGG--AFAGIPG-VGPFGGP----QPGVPL 209 + G PGV LPG+ G++ + P GV G A +G+PG +GP G P G P Sbjct: 356 ISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPG 415 Query: 210 GYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAG-----------KAGYPTGTG-VGP 257 I A LPG GLP GP G G ++G+P G GP Sbjct: 416 RTTIGAAGLPGRDGLP----------GPPGPPGPPSPEFETETLHNKESGFPGLRGEQGP 465 Query: 258 QA-AAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG-----AIPGIGGIAG--------- 302 + K + F A GV P G G PG PG +PG+ G G Sbjct: 466 KGNLGLKGIKGDSGFCACDGGV-PNTGPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQG 524 Query: 303 -VGTPAAAAAAAAAAKAAKYG-AAAGLVPGGPGFG--------PGVVGVPGA-GVPGV-G 350 G P + K G + G PG GV+G PG GVPG+ G Sbjct: 525 PAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPG 584 Query: 351 VPG------------AGIPVVPG-------AGIPGAAVPGVVSPEAAAKAAAKAAKYGAR 391 +PG G+P +PG G+PG +PG+ P K G + Sbjct: 585 LPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQQ 644 Query: 392 PGVGVGGI-----------PTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGV 440 G GI P+ G GFPG G G+PG G PG G G G PG+ Sbjct: 645 GLPGSKGITLPCIIPGSYGPSGFPGTPGFPG-PKGSRGLPGTPGQPGSSGSKGEPGSPGL 703 Query: 441 GISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGV 500 PE + K G P +PG PG+ +PG+ + G Sbjct: 704 VHLPELPGFPGPRGEKGLPGFPG---------------LPGKDGLPGMIGSPGLPGSKGA 748 Query: 501 --GLAPGVGVAPGVGVAPGVGVAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPG 557 + APG G+ G +G G+ V K L G G PG Sbjct: 749 TGDIFGAENGAPGEQGLQGLTGHKGFLGDSGL----PGLKGVHGKPGLLGPKG-ERGSPG 803 Query: 558 LGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGAL-------AAAKAAKYGAAV----PG 606 VG PG +G G+ +G+PG PG K G+ V PG Sbjct: 804 TPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPG 863 Query: 607 VLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVG 666 + G G G VG+ G G A A + + G VG G+ GL G+PG Sbjct: 864 LKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLP----GIPGTR 919 Query: 667 GLGGIPPAAAAKAAKYGVAARPG 689 GL GI P + K G A PG Sbjct: 920 GLKGI-PGSTGKMGPSGRAGTPG 941 Score = 140 bits (354), Expect = 3e-33 Identities = 227/768 (29%), Positives = 288/768 (37%), Gaps = 133/768 (17%) Query: 23 PSRPG--GVPGAI-----PG--GVPGGVF-----YPGA-GLGALGG--GALGPGGKP-LK 64 P PG G+PG I PG G G +F PG GL L G G LG G P LK Sbjct: 725 PGLPGKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLK 784 Query: 65 PVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGL--- 121 V G GL G + PG + G ++ Y K +GL G PG G+ Sbjct: 785 GVHGK---PGLLGPKGERGSPGTPGQVGQPGTPGSSGPY-GIKGKSGLPGAPGFPGISGH 840 Query: 122 ----GVSAAPSVPGAVVPQPGAGVK--PGKVPGVGL------PGVYPGGVLPGAR----- 164 G PG++V + G+K PG VGL PGV L G + Sbjct: 841 PGKKGTRGKKGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGS 900 Query: 165 -----FPGVGVLPGVPTGAGVKPKAPGVGGAF-----AGIPGV-------GPFGGPQPGV 207 FPG+ LPG+P G+K PG G AG PG GP G P P Sbjct: 901 VGFVGFPGIPGLPGIPGTRGLKG-IPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRR 959 Query: 208 PLGYP-IKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAK 266 P+ +K K G G + G P G G AG G G P G+ P + K Sbjct: 960 PMSNLWLKGDK--GSQGSAGSNG-FPGPRGDKGEAGRPGPPGLPGAPGL-PGIIKGVSGK 1015 Query: 267 AAAKFGAGAAGVLPGV-GGAGVPGVPGAIPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAA 324 G G LPG+ G +G+ G PG +PG G G+ G+P A+ G Sbjct: 1016 PGPPGFMGIRG-LPGLKGSSGITGFPG-MPGESGSQGIRGSPGLPGASGLPGLKGDNGQT 1073 Query: 325 AGLVPG-GPGFGPGVVGVPGAG-----VPGVGVPG-----AGIPVVPGAGIPGA-AVPGV 372 + GP PG G G + +G PG + V G+PGA PGV Sbjct: 1074 VEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGV 1133 Query: 373 VSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGF-GV-GVGGIPG--------- 421 + GA +G G+ +G GFPGF G+ G+ G+PG Sbjct: 1134 AGMRGEPGLPGSSGHQGAIGPLGSPGL----IGPKGFPGFPGLHGLNGLPGTKGTHGTPG 1189 Query: 422 --VAGVPGVGGVPGVGG---VPGVGISPEAQAAAAAKAAKYG-------VGTPAAAAAKA 469 + GVPG G+PG G PG+GI + + G G P A Sbjct: 1190 PSITGVPGPAGLPGPKGEKGYPGIGIGAPGKPGLRGQKGDRGFPGLQGPAGLPGAPGISL 1249 Query: 470 AAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI----G 525 + A PG G PG PG PG G PG PG G Sbjct: 1250 PSLIAGQPGDPGRPGLDGERGRPGPAGPPG---PPGPSSNQGDTGDPGFPGIPGPKGPKG 1306 Query: 526 PGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGF 585 G+ + ++ K +R G G PG VG PG G+ G G G Sbjct: 1307 DQGIPGFSGLPGELGLKG-MRGEPGF-MGTPGK---VGPPGDPGFPGMKGKAGPRGSSGL 1361 Query: 586 GAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFG 645 PG A+A + VP G LG G GIPG + P A +K G Sbjct: 1362 QGDPGQTPTAEAVQ----VPP--GPLGLPGIDGIPG--LTGDPGAQGPVGLQGSKGLP-G 1412 Query: 646 LVGAAGLGGL--GVGGLGVPGVGGLGGIP--PAAAAKAAKYGVAARPG 689 + G G GL G LG PG+ GL G P A + +G+ PG Sbjct: 1413 IPGKDGPSGLPGPPGALGDPGLPGLQGPPGFEGAPGQQGPFGMPGMPG 1460 Score = 138 bits (347), Expect = 2e-32 Identities = 209/707 (29%), Positives = 253/707 (35%), Gaps = 155/707 (21%) Query: 1 MAGLTAAAPRPGVLLLLLSILHPSRPG-----GVPGAI-PGGVPGGVFYPGA-GLGALGG 53 + GL +PG+L P PG G PG+ P G+ G PGA G + G Sbjct: 780 LPGLKGVHGKPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISG 839 Query: 54 GALGPGGKPLKPVPGGLAGAGLGAGLGAFPA----VTFPGALVPGGVAD--AAAAYKAAK 107 G + K PG + GL GL P V G+ GVA A + K K Sbjct: 840 HPGKKGTRGKKGPPGSIVKKGL-PGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEK 898 Query: 108 AGAGLGGVPGVGGL-------GVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGV- 159 G G PG+ GL G+ P G + P AG PG+ G PG P G+ Sbjct: 899 GSVGFVGFPGIPGLPGIPGTRGLKGIPGSTGKMGPSGRAGT-PGEKGDRGNPG--PVGIP 955 Query: 160 -------------------------LPGAR-------------FPGVGVLPGVPTGAGVK 181 PG R PG LPG+ G K Sbjct: 956 SPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGK 1015 Query: 182 PKAPGVGGAFAGIPGV----GPFGGP-QPGVPLGYPIK-APKLPGGYGLPYTTGKL---- 231 P PG G G+PG+ G G P PG I+ +P LPG GLP G Sbjct: 1016 PGPPGFMG-IRGLPGLKGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTV 1074 Query: 232 -------PYGY-GPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVG 283 P G G G G G+ G G + G A PGV Sbjct: 1075 EISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVA 1134 Query: 284 GA-GVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGF----GPGV 338 G G PG+PG+ G I +G+P +G +PG G GP + Sbjct: 1135 GMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLNG--LPGTKGTHGTPGPSI 1192 Query: 339 VGVPG-AGVPGV----GVPGAGI--PVVPG----------------AGIPGAAVPGVVSP 375 GVPG AG+PG G PG GI P PG AG+PGA PG+ P Sbjct: 1193 TGVPGPAGLPGPKGEKGYPGIGIGAPGKPGLRGQKGDRGFPGLQGPAGLPGA--PGISLP 1250 Query: 376 EAAAKAAAKAAKYG-----ARPG-VGVGGIP--TYGVGAGGFPGFGVGVGGIPGVAGVPG 427 A + G RPG G G P + G G PGF GIPG G G Sbjct: 1251 SLIAGQPGDPGRPGLDGERGRPGPAGPPGPPGPSSNQGDTGDPGFP----GIPGPKGPKG 1306 Query: 428 VGGVPGVGGVPG-VGISP-EAQAAAAAKAAKYGV-GTPAAAAAKA-AAKAAQFGLVPGVG 483 G+PG G+PG +G+ + K G G P K A GL G Sbjct: 1307 DQGIPGFSGLPGELGLKGMRGEPGFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQGDPG 1366 Query: 484 VAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKA 543 P A V V PG PG+ PG+ PG GP G Sbjct: 1367 QTP---TAEAVQVPPGPLGLPGIDGIPGLTGDPGAQ-----GPVG--------------- 1403 Query: 544 QLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPG 590 L+ + GL GIPG G+PG G PGL G PGF PG Sbjct: 1404 -LQGSKGL-PGIPGKDGPSGLPGPPGALGDPGLPGLQGPPGFEGAPG 1448 Score = 129 bits (325), Expect = 7e-30 Identities = 219/819 (26%), Positives = 292/819 (35%), Gaps = 205/819 (25%) Query: 54 GALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLG 113 G GP G P G G+ +GL FPG L P G K G Sbjct: 49 GRPGPIGIQGPTGPQGFTGSTGLSGLKGERG--FPGLLGPYG----------PKGDKGPM 96 Query: 114 GVPGVGGLGVSAAPSVPGAVVPQ--PGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVL 171 GVPG LG++ P PG P+ PG G VG PG P G +PG+ Sbjct: 97 GVPGF--LGINGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPG--PDG------YPGLLGP 146 Query: 172 PGVPTGAGVK----------------PKAPGVGG-----AFAGIPG-VGPFGGP----QP 205 PG+P G K P PG+ G G PG VGP G P P Sbjct: 147 PGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPP 206 Query: 206 GVP--------LGYPIKAPK-------LPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYP 250 G P +G + K LPG G P +TG+L + P G G+ G+ G Sbjct: 207 GPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPK 266 Query: 251 TGTGVGPQAAAAAAAKAAAKFGAGAAGV--LPG----VGGAGVPGVPG--------AIPG 296 G+ K G G+ LPG +G GV G PG PG Sbjct: 267 GFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPG 326 Query: 297 IGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG------------- 343 + G G+ A ++ G PG PGV G+PG Sbjct: 327 LNGFQGIEGQKGDIGLPGPDVFIDIDGA--VISGNPG-DPGVPGLPGLKGDEGIQGLRGP 383 Query: 344 AGVPGV----GVPGA----GIPVVPG------------AGIPG-------AAVPGVVSPE 376 +GVPG+ GVPGA G P + G AG+PG PG SPE Sbjct: 384 SGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPE 443 Query: 377 AAAKA--------AAKAAKYGARPGVGV-------------GGIPTYG-VGAGGFPG-FG 413 + + G + +G+ GG+P G G G PG +G Sbjct: 444 FETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWG 503 Query: 414 -VGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAK 472 +G+ G+ G G G GG G G PG+ + P + K + + T Sbjct: 504 LIGLPGLKGARGDRGSGGAQGPAGAPGL-VGPLGPSGPKGKKGEPILSTIQGMPGDRGDS 562 Query: 473 AAQ--FGLV--PGVGVAPGVGVAPGVGVAPGVGL--------APGVGVAPGVGVAPGVGV 520 +Q G++ PG PG+ PG+ G G PG PG PG G+ Sbjct: 563 GSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPGLPGNGL 622 Query: 521 APGI-GPGGVAAAAKSAAKVAAKAQLRAAAG--LGAGIPGLGVGVGVPGLGVGAGVPGLG 577 PG+ GP G+ K + + L + G L IPG G PG G PG Sbjct: 623 -PGLPGPRGL-PGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGT---PGFPGPK 677 Query: 578 VGAGVPGFGAVPGALAA-----AKAAKYGAAVPGVLGGLGALGGVGIPG--------GVV 624 G+PG PG+ + + + +PG G G G G PG G++ Sbjct: 678 GSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMI 737 Query: 625 GAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLG-----VGGLGVPGVGGLGGIP------- 672 G+ + A A+ G G GL GL +G G+PG+ G+ G P Sbjct: 738 GSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKG 797 Query: 673 -------------PAAAAKAAKYGVAARPGFGLSPIFPG 698 P + YG+ + G +P FPG Sbjct: 798 ERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPG 836 Score = 120 bits (302), Expect = 3e-27 Identities = 164/535 (30%), Positives = 211/535 (39%), Gaps = 99/535 (18%) Query: 28 GVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVT- 86 G PG P G+PG PG G G KP P G G GL +T Sbjct: 992 GRPG--PPGLPGAPGLPGIIKGVSG-----------KPGPPGFMGIRGLPGLKGSSGITG 1038 Query: 87 FPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG-----LGVSAAPSVPGAVVPQPG-AG 140 FPG +PG + + + G G+PG+ G + +S +P G QPG +G Sbjct: 1039 FPG--MPG--ESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKG----QPGESG 1090 Query: 141 VK-----PGKVPGVGLPGVYPG----GVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAF 191 K G + +G PG GV PG PG P AG++ + PG+ G+ Sbjct: 1091 FKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGA---PGFPGVAGMRGE-PGLPGSS 1146 Query: 192 AGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTG-------KLPYGYGPGGVAGAA 244 +GP G P P G+P P L G GLP T G + GP G+ G Sbjct: 1147 GHQGAIGPLGSPGLIGPKGFP-GFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPK 1205 Query: 245 GKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGG-AGVPGVPG-AIPGIGGIAG 302 G+ GYP G G+G A K + G G PG+ G AG+PG PG ++P + IAG Sbjct: 1206 GEKGYP-GIGIG------APGKPGLRGQKGDRG-FPGLQGPAGLPGAPGISLPSL--IAG 1255 Query: 303 VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AGVPGV-------GVPG- 353 P + + G A P GP G G PG G+PG G+PG Sbjct: 1256 --QPGDPGRPGLDGERGRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGF 1313 Query: 354 AGIPVVPGA----GIPG-AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGG 408 +G+P G G PG PG V P K G R G+ G P G Sbjct: 1314 SGLPGELGLKGMRGEPGFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQGDP-------G 1366 Query: 409 FPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAK 468 V PG G+PG+ G+PG+ G PG AQ + +K G P Sbjct: 1367 QTPTAEAVQVPPGPLGLPGIDGIPGLTGDPG------AQGPVGLQGSKGLPGIP------ 1414 Query: 469 AAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG 523 K GL PG A G PG+ PG APG G+ PG + G Sbjct: 1415 --GKDGPSGL-PGPPGALGDPGLPGLQGPPGFEGAPGQQGPFGMPGMPGQSMRVG 1466 Score = 89.0 bits (219), Expect = 1e-17 Identities = 154/550 (28%), Positives = 192/550 (34%), Gaps = 110/550 (20%) Query: 198 GPFGGPQPGVPLGYPIKA--PKLPGGYGLPYTTGKLPYG----YGPGGVAGAAGKAGYPT 251 GP G P P G+ L G G P G PYG GP GV G G G P Sbjct: 52 GPIGIQGPTGPQGFTGSTGLSGLKGERGFPGLLG--PYGPKGDKGPMGVPGFLGINGIPG 109 Query: 252 GTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAI--PGIGGIAGV-GTPA 307 G GP+ G G VG G G PG + PG+ G G G P Sbjct: 110 HPGQPGPRGPPGLD---------GCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPV 160 Query: 308 AAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPGVGVPGAGIPVVPGA--GI 364 A + K G PG PG+ G+ G G PG PGA P P G Sbjct: 161 LAPGSFKGMK------------GDPGL-PGLDGITGPQGAPGF--PGAVGPAGPPGLQGP 205 Query: 365 PGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGI--PTYGVGAGGFPGFGVGVGGIPGV 422 PG PG + P+ + K G + VG+ G P G F GF G G G Sbjct: 206 PGP--PGPLGPDGNMGLGFQGEK-GVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGE 262 Query: 423 AGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGV 482 G G G+ G G PG+G + E K K G P + + PG Sbjct: 263 PGPKGFPGISGPPGFPGLGTTGE-------KGEKGEKGIPGLPGPRGPMGSEGVQGPPGQ 315 Query: 483 GVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGV---APGVGVAPGIGPGGVAAAAKSAAKV 539 G PG+ G+ G PG V G ++ G GV Sbjct: 316 QGKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVP--------- 366 Query: 540 AAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAK 599 G+PGL G+ GL +GVPGL +GVPG P K + Sbjct: 367 --------------GLPGLKGDEGIQGLRGPSGVPGLPALSGVPG-ALGPQGFPGLKGDQ 411 Query: 600 YGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAA-AKAAQF-GLVGAAG-LGGLG 656 G +G G G G+PG GP + + K + F GL G G G LG Sbjct: 412 -GNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLG 470 Query: 657 VGGL----------------------GVPGVGGLGGIPPAAAAKAAK-----YGVAARPG 689 + G+ G PG GL G+P A+ + G A PG Sbjct: 471 LKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPG 530 Query: 690 FGLSPIFPGG 699 + P+ P G Sbjct: 531 L-VGPLGPSG 539 >gi|48762934 alpha 2 type I collagen [Homo sapiens] Length = 1366 Score = 166 bits (421), Expect = 5e-41 Identities = 222/702 (31%), Positives = 263/702 (37%), Gaps = 94/702 (13%) Query: 54 GALGPGGKPLKPVPGGLAG------AGLGAGLGAFPAVTFPGALVPGGVADAAAA--YKA 105 G GP G P P P GL G G G GLG P G + P G AA A + Sbjct: 57 GPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPGPM----GLMGPRGPPGAAGAPGPQG 112 Query: 106 AKAGAGLGGVPGVGGLGVSAAPSVPGAVVPQPGAGVKPGKVPGV----------GLPGVY 155 + AG G PG G + P+ P + G KPG+ PG G PG Sbjct: 113 FQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGR-PGERGVVGPQGARGFPGT- 170 Query: 156 PGGVLPGAR----FPGVGVLPGVPTGAGVK--PKAPGVGG-----AFAGIPGV-GPFGGP 203 PG LPG + G+ L G P GVK P APG G G+PG G G P Sbjct: 171 PG--LPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAP 228 Query: 204 QPGVPLGY-----------PIKAPKLPGGYGLPYTTGKLPY--GYGPGGVAGAAGKAGYP 250 P G PI + PG G P G++ GP G AG G+ G P Sbjct: 229 GPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLP 288 Query: 251 TGTG-VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGA-GVPGVPGAIPGIGGIAG------ 302 +G VGP A AK GAAG LPGV GA G+PG P IPG G AG Sbjct: 289 GLSGPVGPPGNPGANGLTGAK---GAAG-LPGVAGAPGLPG-PRGIPGPVGAAGATGARG 343 Query: 303 -VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPG-AGIPVVP 360 VG P A + + + G+A P GP G G P G PG G+ P Sbjct: 344 LVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRG-PNGEAGSAGPPGPPGLRGSP 402 Query: 361 GA-GIPGA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGF--GVGV 416 G+ G+PGA GV+ P + A+ A G G G P +G G PG +G Sbjct: 403 GSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGL-MGPRGLPGSPGNIGP 461 Query: 417 GGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQF 476 G G G+PG+ G PG G G P K G P K A A Sbjct: 462 AGKEGPVGLPGIDGRPGPIGPAGARGEP---GNIGFPGPKGPTGDPGKNGDKGHAGLAGA 518 Query: 477 GLVPGVGVAPGVGVAPG-VGVAPGVGL-----APGVGVAPGVGVAPGVGVAPG----IGP 526 PG G PG GV G G PG PG G PG G Sbjct: 519 RGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGE 578 Query: 527 GGVAAAAKSAAKVAAKAQLRAAAGLG-------AGIPGLGVGVGVPGLGVGAGVPGLGVG 579 G+ A + + AA G +G PG G PG+ G G Sbjct: 579 FGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGP 638 Query: 580 AGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAA 639 +G+PG G + K K + G +G G G G PG V GPA A A Sbjct: 639 SGLPGERGAAG-IPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAG 697 Query: 640 KAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAK 681 A G G G G G +G G G G AA AK Sbjct: 698 AAGPAGPAGPRGSPG-ERGEVGPAGPNGFAGPAGAAGQPGAK 738 Score = 160 bits (405), Expect = 4e-39 Identities = 230/716 (32%), Positives = 266/716 (37%), Gaps = 95/716 (13%) Query: 26 PGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAV 85 P G PG G PG PGA A G +GP G P G+ G AG P + Sbjct: 392 PPGPPGL--RGSPGSRGLPGADGRA---GVMGPPGSRGASGPAGVRGPNGDAGRPGEPGL 446 Query: 86 TFPGALVPGGVADAAAAYKAAKAGA-GLGGVPG-VGGLGVSAAPSVPGAVVPQPGAGVKP 143 P L PG + A K G G+ G PG +G G P G P+ G P Sbjct: 447 MGPRGL-PGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTG-DP 504 Query: 144 GKVPGVGLPGVYPGGVLPGAR-FPGVGVLPGVPTGAGVKPKAPGVGGAFA--GIPGVGPF 200 GK G G L GAR PG P GA P GV G G PG F Sbjct: 505 GKNGDKGHAG------LAGARGAPG----PDGNNGAQGPPGPQGVQGGKGEQGPPGPPGF 554 Query: 201 GG-PQPGVPLGYPIKAPK--LPGGYGLPYTTGKLPYGY-GPGGVAGAAGKAGYPTGTG-- 254 G P P P G K + L G +GLP G P G GP G +GAAG G P G+ Sbjct: 555 QGLPGPSGPAGEVGKPGERGLHGEFGLPGPAG--PRGERGPPGESGAAGPTG-PIGSRGP 611 Query: 255 ---------------VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAI--PGI 297 VG A + + GAAG+ G G G PG+ G I PG Sbjct: 612 SGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGR 671 Query: 298 GGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGI 356 G G G A A A + GAA P GP PG G G P AG Sbjct: 672 DGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGA 731 Query: 357 PVVPGA-GIPGAAVP----GVVSPEAAAKAAAKAAKYGARPGV----GVGGIPTYGVGAG 407 PGA G GA P GVV P AA A G PG G GG P G Sbjct: 732 AGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGP-PGPAGSRGDGGPP----GMT 786 Query: 408 GFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYG-VGTPAAAA 466 GFPG G G PG +G+ G G PG G G+ P + + G VG P A Sbjct: 787 GFPG-AAGRTGPPGPSGISGPPGPPGPAGKEGLR-GPRGDQGPVGRTGEVGAVGPPGFAG 844 Query: 467 AKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGV-GVAPGVGVAPGVGVAPGIG 525 K + A PG G+ APG+ PG G+ GVA VG +G+A G Sbjct: 845 EKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPG 904 Query: 526 PGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGF 585 G A S G PG G PG G PG G G Sbjct: 905 ARGPPGAVGSPGV--------------NGAPGEAGRDGNPG---NDGPPGRDGQPGHKGE 947 Query: 586 GAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFG 645 PG + A A PG G +G G G G +GP A A + G Sbjct: 948 RGYPGNIGPVGA----AGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQG 1003 Query: 646 LVGAAG-LGGLGVGGL-GVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPGG 699 + G G G G GL G+ G GL G+P A +G PG + P P G Sbjct: 1004 IRGDKGEPGEKGPRGLPGLKGHNGLQGLP----GIAGHHGDQGAPG-SVGPAGPRG 1054 Score = 134 bits (337), Expect = 3e-31 Identities = 176/562 (31%), Positives = 206/562 (36%), Gaps = 64/562 (11%) Query: 172 PGVPTGAGVKPKAPGVGGAFAG-IPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGK 230 P P G P PG+GG FA G G GP P +G + P PG G P Sbjct: 58 PTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPGPMGLMGP--RGP--PGAAGAP----- 108 Query: 231 LPYGYGPGGVAGAAGKAGYPTGTG-------VGPQAAAAAAAKAAAKFGAGAAGVLPGVG 283 GP G G AG+ G P TG GP A G GV+ G Sbjct: 109 -----GPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVVGPQG 163 Query: 284 GAGVPGVPGAIPGIGGIAG-------VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGP 336 G PG PG +PG GI G G P A + G G Sbjct: 164 ARGFPGTPG-LPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGER 222 Query: 337 GVVGVPG-AGVPG----VGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGAR 391 G VG PG AG G VG G P+ AG PG PG P+ A A G Sbjct: 223 GRVGAPGPAGARGSDGSVGPVGPAGPI-GSAGPPG--FPGAPGPKGEIGAVGNAGPAGPA 279 Query: 392 PGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAA 451 G G+P G G PG G G+ G G G+ GV G G+PG P AA Sbjct: 280 GPRGEVGLPGLS-GPVGPPG-NPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAG 337 Query: 452 AKAAKYGVGTPAAAAAKAAA-------KAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAP 504 A A+ VG P A +K + A G PG G G + G P Sbjct: 338 ATGARGLVGEPGPAGSKGESGNKGEPGSAGPQG-PPGPSGEEGKRGPNGEAGSAGPPGPP 396 Query: 505 GVGVAPGVGVAPGV-GVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVG 563 G+ +PG PG G A +GP G ++ A+ A AG G PGL G Sbjct: 397 GLRGSPGSRGLPGADGRAGVMGPPG----SRGASGPAGVRGPNGDAG-RPGEPGLMGPRG 451 Query: 564 VPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGV 623 +PG G G G+PG PG + A A PG +G G G G PG Sbjct: 452 LPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGA----RGEPGNIGFPGPKGPTGDPGKN 507 Query: 624 VGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL--GVGGLGVPGVGGLGGI--PPAAAAKA 679 G A A A A G G G G+ G G G PG G G+ P A + Sbjct: 508 GDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEV 567 Query: 680 AKYGVAARPG-FGL-SPIFPGG 699 K G G FGL P P G Sbjct: 568 GKPGERGLHGEFGLPGPAGPRG 589 Score = 74.3 bits (181), Expect = 4e-13 Identities = 92/303 (30%), Positives = 107/303 (35%), Gaps = 35/303 (11%) Query: 415 GVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKY-GVGTPAAAAAKAAAKA 473 G G G G PG G G G PG P AA+Y G G Sbjct: 39 GPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGV------------ 86 Query: 474 AQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG-IGPGGVAAA 532 GL PG G PG APG G PG G A G GP G A Sbjct: 87 ---GLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGE 143 Query: 533 AKSAAKVAAKAQLRAAAGLGA----GIPGLG--VGV----GVPGLGVGAGVPGLGVGAGV 582 K + GA G PGL G+ G+ GL G PG+ G Sbjct: 144 DGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGA 203 Query: 583 PGFGAVPGALAA----AKAAKYGAAVP-GVLGGLGALGGVGIPGGVVGAGPAAAAAAAKA 637 PG PG A + + GA P G G G++G VG G + AGP A Sbjct: 204 PGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGP 263 Query: 638 AAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIP--PAAAAKAAKYGVAARPGFGLSPI 695 + G G AG G G +G+PG+ G G P P A G A PG +P Sbjct: 264 KGEIGAVGNAGPAGPAG-PRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPG 322 Query: 696 FPG 698 PG Sbjct: 323 LPG 325 >gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo sapiens] Length = 1487 Score = 162 bits (410), Expect = 1e-39 Identities = 231/746 (30%), Positives = 265/746 (35%), Gaps = 108/746 (14%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAG----AGLGAG 78 P P G PG P G G PG + G GP G P KP G AG AG Sbjct: 211 PPGPAGAPG--PQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGP 268 Query: 79 LGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGL-GVSAAPSVPGAVVPQP 137 G A FPG GV G G PG+ G G + AP V G P Sbjct: 269 PGPQGARGFPGTPGLPGVK-------------GHRGYPGLDGAKGEAGAPGVKGES-GSP 314 Query: 138 GAGVKPGKVPGVGLPG----VYPGGVLPGARF----PGVGVLPGV--PTGAGVKPKAPGV 187 G PG + GLPG P G GAR PG PG P G P APG Sbjct: 315 GENGSPGPMGPRGLPGERGRTGPAGAA-GARGNDGQPGPAGPPGPVGPAGGPGFPGAPGA 373 Query: 188 GGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKA 247 G GP G P G P +P G G P T G +P G G G AG Sbjct: 374 KGEAGPTGARGPEGAQGPRGEPGTP-GSPGPAGASGNPGTDG-IPGAKGSAGAPGIAGAP 431 Query: 248 GYPTGTGV-GPQAA---------------AAAAAKAAAKFGAGAAGVLPGVGGAGVPGVP 291 G+P G GPQ A A + K G AG G AG G Sbjct: 432 GFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKR 491 Query: 292 GAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AGVPGV- 349 GA GG+ +G P A + G A GP PG G G AG G Sbjct: 492 GARGEPGGVGPIGPPGERGAPGNRGFPGQDGLA------GPKGAPGERGPSGLAGPKGAN 545 Query: 350 GVPGA-GIPVVPGA-GIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAG 407 G PG G P +PGA G+ G PG P+ + + G RPG P GA Sbjct: 546 GDPGRPGEPGLPGARGLTGR--PGDAGPQGKVGPSGAPGEDG-RPG------PPGPQGAR 596 Query: 408 GFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAA 467 G PG +G G G G PG G G+ G PG+ P A G Sbjct: 597 GQPGV-MGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGE 655 Query: 468 KAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI--- 524 + A + F +PG PG G PG PG APG+ G PG +PG Sbjct: 656 QGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGL 715 Query: 525 -GPGGVAA-----AAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGL-----GVG--- 570 GP G+ K A+ A + GL G+PG G+ G VG Sbjct: 716 QGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGL-QGMPGERGAAGIAGPKGDRGDVGEKG 774 Query: 571 -AGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGG------VGIPGGV 623 G PG G G+ G PG A A K PG G GA G G PG Sbjct: 775 PEGAPGKDGGRGLTGPIGPPGP-AGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPA 833 Query: 624 VGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGI-----------P 672 AGP A A + + G G AG G G G PG G G+ P Sbjct: 834 GFAGPPGADGQPGAKGEQGEAGQKGDAGAPG-PQGPSGAPGPQGPTGVTGPKGARGAQGP 892 Query: 673 PAAAAKAAKYGVAARPGFGLSPIFPG 698 P A G PG +P PG Sbjct: 893 PGATGFPGAAGRVGPPGSNGNPGPPG 918 Score = 152 bits (383), Expect = 1e-36 Identities = 234/745 (31%), Positives = 261/745 (35%), Gaps = 118/745 (15%) Query: 26 PGGVPGAIPGGVPGGVFYPGAGLGALGG-GALGPGGKPLKPVPGGLAGAGLGAGLGAFPA 84 P G PG P G P G P G G GA GP G+ +P G G Sbjct: 118 PKGPPG--PQG-PAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGP----------- 163 Query: 85 VTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVVPQPGAGVKPG 144 PG P G + A AG G G LGV P P PG PG Sbjct: 164 ---PGPPGPPGPPGLGGNFAAQMAG-GFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPG 219 Query: 145 KVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPG-VGPFGGP 203 G PG PG PGV P P G P PG G AG PG G G P Sbjct: 220 PQGFQGNPGE------PGE--PGVSG-PMGPRGPPGPPGKPGDDGE-AGKPGKAGERGPP 269 Query: 204 QPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTG-VGPQAAAA 262 P G+P P LPG G G L G G G G++G P G GP Sbjct: 270 GPQGARGFP-GTPGLPGVKGHRGYPG-LDGAKGEAGAPGVKGESGSPGENGSPGPMGPRG 327 Query: 263 AAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYG 322 + AGAAG G G G PG + GG G P A A G Sbjct: 328 LPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEG 387 Query: 323 AAAGL----VPGGPG-----FGPGVVGVPG----AGVPGV-GVPG----AGIPVVPGA-- 362 A PG PG PG G+PG AG PG+ G PG G P GA Sbjct: 388 AQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATG 447 Query: 363 --------GIPGAA----------VPGVVSPEAAAKAAAKAAKYGAR--PGVGVGGI-PT 401 G PG A PG P+ A A + K GAR PG GVG I P Sbjct: 448 PLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPG-GVGPIGPP 506 Query: 402 YGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGT 461 GA G GF G G+ G G PG G G+ G G P A+ G Sbjct: 507 GERGAPGNRGF-PGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGR 565 Query: 462 PAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVA---PGVGVAPGV 518 P A + K G PG PG G PGV PG A PG G+ Sbjct: 566 PGDAGPQ--GKVGPSG-APGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGL 622 Query: 519 GVAPGI-------GPGGVAAAAKSAAKVAAKAQLRAAAGLG-------AGIPGLGVGVGV 564 APG+ G G A A + + A G G PG G G Sbjct: 623 PGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGD 682 Query: 565 PGLGVGAGVPGLGVG----AGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIP 620 G+ AG PGL VG G PG PGA + + PG G GA G G P Sbjct: 683 QGVPGEAGAPGL-VGPRGERGFPGERGSPGA-QGLQGPRGLPGTPGTDGPKGASGPAGPP 740 Query: 621 G--------GVVGAGPAAAAAAAKA-AAKAAQFGLVGAAGL-GGLGV-GGLGVPGVGGLG 669 G G+ G AA A K + G GA G GG G+ G +G PG G Sbjct: 741 GAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGAN 800 Query: 670 GI-----PPAAAAKAAKYGVAARPG 689 G PP A A G G Sbjct: 801 GEKGEVGPPGPAGSAGARGAPGERG 825 Score = 142 bits (357), Expect = 1e-33 Identities = 231/752 (30%), Positives = 268/752 (35%), Gaps = 132/752 (17%) Query: 26 PGGV-PGAIPG--GVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGA-GLGAGLGA 81 PGGV P PG G PG +PG G GP G P + P GLAG G G Sbjct: 497 PGGVGPIGPPGERGAPGNRGFPGQD------GLAGPKGAPGERGPSGLAGPKGANGDPGR 550 Query: 82 FPAVTFPGAL-VPGGVADAAAAYKAAKAGA-GLGGVPGVGG-LGVSAAPSVPGAVVPQPG 138 PGA + G DA K +GA G G PG G G P V G P+ G Sbjct: 551 PGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPK-G 609 Query: 139 AGVKPGKVPGVGLPGVYPGGVLPG-------ARFPGVGVLPGVPTGAGVKPKAPGVGGAF 191 A +PGK GLPG LPG A PG P P G + APG G F Sbjct: 610 ANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPG----PAGPAGERGEQGAPGPSG-F 664 Query: 192 AGIPGV-GPFG-GPQPG---VP--LGYP-IKAPK----LPGGYGLPYTTGK-----LPYG 234 G+PG GP G G +PG VP G P + P+ PG G P G LP Sbjct: 665 QGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGT 724 Query: 235 YGPGGVAGAAGKAGYPTGTGV-------GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGV 287 G G GA+G AG P G G + AA A + G G G G Sbjct: 725 PGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGG 784 Query: 288 PGVPGAI--PGIGGIAG----VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGV 341 G+ G I PG G G VG P A +A A + G P G PG G Sbjct: 785 RGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQ 844 Query: 342 PGA-------------GVPGV----GVPGAGIPV-------------VPGA-GIPGAA-- 368 PGA G PG G PG P PGA G PGAA Sbjct: 845 PGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGR 904 Query: 369 -----VPGVVSPEAAAKAAAKAAKYGAR-----------PGV-GVGGIPTYG-------- 403 G P + K GAR PG+ G G P Sbjct: 905 VGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGP 964 Query: 404 VGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPA 463 GA G PG G+ G G+ G+PG G G G+PG P Q A A + G P Sbjct: 965 SGAEGPPG-PQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDR---GPPG 1020 Query: 464 AAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG 523 A PG +PG PG A GV G A G APG +P Sbjct: 1021 PVGPPGLTGPAG---EPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSP- 1076 Query: 524 IGPGGVAAAAKSAAKVAAKAQLRAAAGLGA-GIPGLGVGVGVPGLGVGAGVPGLGVGAGV 582 GP G + A+ + + GA GI G G G G GL G Sbjct: 1077 -GPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGF 1135 Query: 583 PGFGAVPGAL-------AAAKAAKYG-AAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAA 634 G +PG A+ A G PG +G G G GIPG + GP + Sbjct: 1136 TGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGE 1195 Query: 635 AKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVG 666 A G G G G G+ G+G Sbjct: 1196 TGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLG 1227 Score = 125 bits (314), Expect = 1e-28 Identities = 179/567 (31%), Positives = 203/567 (35%), Gaps = 75/567 (13%) Query: 172 PGVPTGAGVKPKAPGVGGAFAGIPG-----VGPFGGPQPGVPLGY--PIKAPKLPGGYGL 224 P PT PG G G PG VGP G P P P G P G G Sbjct: 87 PICPTDLATASGQPGPKGQ-KGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGA 145 Query: 225 PYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVL----- 279 P G+ PG G G G P G+G AA A K G GV+ Sbjct: 146 PGPRGRDGEPGTPGN-PGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMG 204 Query: 280 -------PGVGGA-------GVPGVPGAIPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAA 324 PG GA G PG PG PG+ G G G P +A K G A Sbjct: 205 PMGPRGPPGPAGAPGPQGFQGNPGEPGE-PGVSGPMGPRGPPGPPGKPGDDGEAGKPGKA 263 Query: 325 AGLVPGGP----GFGPGVVGVPGA----GVPGV-GVPG-AGIPVVPG-AGIPGA-AVPGV 372 P GP GF PG G+PG G PG+ G G AG P V G +G PG PG Sbjct: 264 GERGPPGPQGARGF-PGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGP 322 Query: 373 VSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPG-----FGVGVGGIPGVAGVPG 427 + P + GA G G P G G PG G G G PG G G Sbjct: 323 MGPRGLPGERGRTGPAGAAGARGNDGQP----GPAGPPGPVGPAGGPGFPGAPGAKGEAG 378 Query: 428 VGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPG 487 G G G G P + A GT AK +A A PG+ APG Sbjct: 379 PTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGA------PGIAGAPG 432 Query: 488 VGVAPGVGVAPGVGLAPGVGVAPGVGVAPGV-GVAPGIGPGGV--AAAAKSAAKVAAKAQ 544 PG PG A G G PG+ G GP G A + A A + Sbjct: 433 F---PGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEG 489 Query: 545 LRAAAGLGAGIPGLGV--GVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGA 602 R A G G+ +G G PG G GL G PG P LA K A Sbjct: 490 KRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERG-PSGLAGPKGANGDP 548 Query: 603 AVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGV 662 PG G GA G G PG AGP + A + + G G G G G +G Sbjct: 549 GRPGEPGLPGARGLTGRPG---DAGPQGKVGPSGAPGEDGRPGPPGPQGARG-QPGVMGF 604 Query: 663 PGVGGLGGIPPAAAAKAAKYGVAARPG 689 PG G G P KA + G+ PG Sbjct: 605 PGPKGANGEP----GKAGEKGLPGAPG 627 Score = 110 bits (274), Expect = 6e-24 Identities = 149/461 (32%), Positives = 168/461 (36%), Gaps = 61/461 (13%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAF 82 P P G GA G G V PG A GA G G+ P P G AG Sbjct: 790 PIGPPGPAGA--NGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGP--------- 838 Query: 83 PAVTFPGAL-VPGGVADAAAAYKAAKAGA----GLGGVPGVGG-LGVSAAPSVPGAVVPQ 136 PGA PG + A + AGA G G PG G GV+ GA P Sbjct: 839 -----PGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGP- 892 Query: 137 PGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPG 196 PGA PG VG PG PG PG G P GA PG AG PG Sbjct: 893 PGATGFPGAAGRVGPPGSNGNPGPPGP--PGPSGKDG-PKGARGDSGPPGR----AGEPG 945 Query: 197 V-GPFGGP----QPGVPLGYPIKAPKLPGGY-------GLPYTTGKLPYGYGPGGVAGAA 244 + GP G P +PG + P P G GLP G+ + G G +G Sbjct: 946 LQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFP-GLPGPSGEP 1004 Query: 245 GKAGYPTGTG-------VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGI 297 GK G P +G VGP A + + GA G G AGV G G + Sbjct: 1005 GKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAV 1064 Query: 298 GGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIP 357 G G P + A K G A P GP G G+ G P AG P Sbjct: 1065 GAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEP 1124 Query: 358 VVPG----AGIPG-AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPG- 411 G G G +PG P A+ A G R G G P+ GA G PG Sbjct: 1125 GERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVG-PSGKDGANGIPGP 1183 Query: 412 FGV----GVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQA 448 G G G G AG PG G PG G PG GI A A Sbjct: 1184 IGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFA 1224 Score = 82.4 bits (202), Expect = 1e-15 Identities = 109/356 (30%), Positives = 128/356 (35%), Gaps = 47/356 (13%) Query: 363 GIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGV 422 G PG + +V P+ A + G R G G G PG G G PG Sbjct: 107 GEPGD-IKDIVGPKGPPGPQGPAGEQGPRGDRG-------DKGEKGAPG-PRGRDGEPGT 157 Query: 423 AGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGV 482 G PG G PG G PG+G + AQ A A AQ G++ G Sbjct: 158 PGNPGPPGPPGPPGPPGLGGNFAAQ---------------MAGGFDEKAGGAQLGVMQGP 202 Query: 483 GVAPGVGVAPGVGVAPGVGLAPGVGVAPG-VGVAPGVGVAPGIGPGGVAAAAKSAAKVAA 541 G PG APG G PG GV+ +G GP G A K Sbjct: 203 MGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGK 262 Query: 542 KAQLRAAAGLGA-------GIPGLGVGVGVPGLGVG---AGVPGLGVGAGVPGFGAVPG- 590 + GA G+PG+ G PGL AG PG+ +G PG PG Sbjct: 263 AGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGP 322 Query: 591 ----ALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAG----PAAAAAAAKAAAKAA 642 L + A G G G G G PG V AG P A A +A A Sbjct: 323 MGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGA 382 Query: 643 QFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPG 698 + G GA G G G G PG G G P AK G A PG +P FPG Sbjct: 383 R-GPEGAQGPRG-EPGTPGSPGPAGASGNPGTDGIPGAK-GSAGAPGIAGAPGFPG 435 >gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo sapiens] Length = 1418 Score = 162 bits (410), Expect = 1e-39 Identities = 231/746 (30%), Positives = 265/746 (35%), Gaps = 108/746 (14%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAG----AGLGAG 78 P P G PG P G G PG + G GP G P KP G AG AG Sbjct: 142 PPGPAGAPG--PQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGP 199 Query: 79 LGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGL-GVSAAPSVPGAVVPQP 137 G A FPG GV G G PG+ G G + AP V G P Sbjct: 200 PGPQGARGFPGTPGLPGVK-------------GHRGYPGLDGAKGEAGAPGVKGES-GSP 245 Query: 138 GAGVKPGKVPGVGLPG----VYPGGVLPGARF----PGVGVLPGV--PTGAGVKPKAPGV 187 G PG + GLPG P G GAR PG PG P G P APG Sbjct: 246 GENGSPGPMGPRGLPGERGRTGPAGAA-GARGNDGQPGPAGPPGPVGPAGGPGFPGAPGA 304 Query: 188 GGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKA 247 G GP G P G P +P G G P T G +P G G G AG Sbjct: 305 KGEAGPTGARGPEGAQGPRGEPGTP-GSPGPAGASGNPGTDG-IPGAKGSAGAPGIAGAP 362 Query: 248 GYPTGTGV-GPQAA---------------AAAAAKAAAKFGAGAAGVLPGVGGAGVPGVP 291 G+P G GPQ A A + K G AG G AG G Sbjct: 363 GFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKR 422 Query: 292 GAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AGVPGV- 349 GA GG+ +G P A + G A GP PG G G AG G Sbjct: 423 GARGEPGGVGPIGPPGERGAPGNRGFPGQDGLA------GPKGAPGERGPSGLAGPKGAN 476 Query: 350 GVPGA-GIPVVPGA-GIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAG 407 G PG G P +PGA G+ G PG P+ + + G RPG P GA Sbjct: 477 GDPGRPGEPGLPGARGLTGR--PGDAGPQGKVGPSGAPGEDG-RPG------PPGPQGAR 527 Query: 408 GFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAA 467 G PG +G G G G PG G G+ G PG+ P A G Sbjct: 528 GQPGV-MGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGE 586 Query: 468 KAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI--- 524 + A + F +PG PG G PG PG APG+ G PG +PG Sbjct: 587 QGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGL 646 Query: 525 -GPGGVAA-----AAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGL-----GVG--- 570 GP G+ K A+ A + GL G+PG G+ G VG Sbjct: 647 QGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGL-QGMPGERGAAGIAGPKGDRGDVGEKG 705 Query: 571 -AGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGG------VGIPGGV 623 G PG G G+ G PG A A K PG G GA G G PG Sbjct: 706 PEGAPGKDGGRGLTGPIGPPGP-AGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPA 764 Query: 624 VGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGI-----------P 672 AGP A A + + G G AG G G G PG G G+ P Sbjct: 765 GFAGPPGADGQPGAKGEQGEAGQKGDAGAPG-PQGPSGAPGPQGPTGVTGPKGARGAQGP 823 Query: 673 PAAAAKAAKYGVAARPGFGLSPIFPG 698 P A G PG +P PG Sbjct: 824 PGATGFPGAAGRVGPPGSNGNPGPPG 849 Score = 152 bits (383), Expect = 1e-36 Identities = 234/745 (31%), Positives = 261/745 (35%), Gaps = 118/745 (15%) Query: 26 PGGVPGAIPGGVPGGVFYPGAGLGALGG-GALGPGGKPLKPVPGGLAGAGLGAGLGAFPA 84 P G PG P G P G P G G GA GP G+ +P G G Sbjct: 49 PKGPPG--PQG-PAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGP----------- 94 Query: 85 VTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVVPQPGAGVKPG 144 PG P G + A AG G G LGV P P PG PG Sbjct: 95 ---PGPPGPPGPPGLGGNFAAQMAG-GFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPG 150 Query: 145 KVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPG-VGPFGGP 203 G PG PG PGV P P G P PG G AG PG G G P Sbjct: 151 PQGFQGNPGE------PGE--PGVSG-PMGPRGPPGPPGKPGDDGE-AGKPGKAGERGPP 200 Query: 204 QPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTG-VGPQAAAA 262 P G+P P LPG G G L G G G G++G P G GP Sbjct: 201 GPQGARGFP-GTPGLPGVKGHRGYPG-LDGAKGEAGAPGVKGESGSPGENGSPGPMGPRG 258 Query: 263 AAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYG 322 + AGAAG G G G PG + GG G P A A G Sbjct: 259 LPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEG 318 Query: 323 AAAGL----VPGGPG-----FGPGVVGVPG----AGVPGV-GVPG----AGIPVVPGA-- 362 A PG PG PG G+PG AG PG+ G PG G P GA Sbjct: 319 AQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATG 378 Query: 363 --------GIPGAA----------VPGVVSPEAAAKAAAKAAKYGAR--PGVGVGGI-PT 401 G PG A PG P+ A A + K GAR PG GVG I P Sbjct: 379 PLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPG-GVGPIGPP 437 Query: 402 YGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGT 461 GA G GF G G+ G G PG G G+ G G P A+ G Sbjct: 438 GERGAPGNRGF-PGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGR 496 Query: 462 PAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVA---PGVGVAPGV 518 P A + K G PG PG G PGV PG A PG G+ Sbjct: 497 PGDAGPQ--GKVGPSG-APGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGL 553 Query: 519 GVAPGI-------GPGGVAAAAKSAAKVAAKAQLRAAAGLG-------AGIPGLGVGVGV 564 APG+ G G A A + + A G G PG G G Sbjct: 554 PGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGD 613 Query: 565 PGLGVGAGVPGLGVG----AGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIP 620 G+ AG PGL VG G PG PGA + + PG G GA G G P Sbjct: 614 QGVPGEAGAPGL-VGPRGERGFPGERGSPGA-QGLQGPRGLPGTPGTDGPKGASGPAGPP 671 Query: 621 G--------GVVGAGPAAAAAAAKA-AAKAAQFGLVGAAGL-GGLGV-GGLGVPGVGGLG 669 G G+ G AA A K + G GA G GG G+ G +G PG G Sbjct: 672 GAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGAN 731 Query: 670 GI-----PPAAAAKAAKYGVAARPG 689 G PP A A G G Sbjct: 732 GEKGEVGPPGPAGSAGARGAPGERG 756 Score = 142 bits (357), Expect = 1e-33 Identities = 231/752 (30%), Positives = 268/752 (35%), Gaps = 132/752 (17%) Query: 26 PGGV-PGAIPG--GVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGA-GLGAGLGA 81 PGGV P PG G PG +PG G GP G P + P GLAG G G Sbjct: 428 PGGVGPIGPPGERGAPGNRGFPGQD------GLAGPKGAPGERGPSGLAGPKGANGDPGR 481 Query: 82 FPAVTFPGAL-VPGGVADAAAAYKAAKAGA-GLGGVPGVGG-LGVSAAPSVPGAVVPQPG 138 PGA + G DA K +GA G G PG G G P V G P+ G Sbjct: 482 PGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPK-G 540 Query: 139 AGVKPGKVPGVGLPGVYPGGVLPG-------ARFPGVGVLPGVPTGAGVKPKAPGVGGAF 191 A +PGK GLPG LPG A PG P P G + APG G F Sbjct: 541 ANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPG----PAGPAGERGEQGAPGPSG-F 595 Query: 192 AGIPGV-GPFG-GPQPG---VP--LGYP-IKAPK----LPGGYGLPYTTGK-----LPYG 234 G+PG GP G G +PG VP G P + P+ PG G P G LP Sbjct: 596 QGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGT 655 Query: 235 YGPGGVAGAAGKAGYPTGTGV-------GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGV 287 G G GA+G AG P G G + AA A + G G G G Sbjct: 656 PGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGG 715 Query: 288 PGVPGAI--PGIGGIAG----VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGV 341 G+ G I PG G G VG P A +A A + G P G PG G Sbjct: 716 RGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQ 775 Query: 342 PGA-------------GVPGV----GVPGAGIPV-------------VPGA-GIPGAA-- 368 PGA G PG G PG P PGA G PGAA Sbjct: 776 PGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGR 835 Query: 369 -----VPGVVSPEAAAKAAAKAAKYGAR-----------PGV-GVGGIPTYG-------- 403 G P + K GAR PG+ G G P Sbjct: 836 VGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGP 895 Query: 404 VGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPA 463 GA G PG G+ G G+ G+PG G G G+PG P Q A A + G P Sbjct: 896 SGAEGPPG-PQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDR---GPPG 951 Query: 464 AAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG 523 A PG +PG PG A GV G A G APG +P Sbjct: 952 PVGPPGLTGPAG---EPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSP- 1007 Query: 524 IGPGGVAAAAKSAAKVAAKAQLRAAAGLGA-GIPGLGVGVGVPGLGVGAGVPGLGVGAGV 582 GP G + A+ + + GA GI G G G G GL G Sbjct: 1008 -GPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGF 1066 Query: 583 PGFGAVPGAL-------AAAKAAKYG-AAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAA 634 G +PG A+ A G PG +G G G GIPG + GP + Sbjct: 1067 TGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGE 1126 Query: 635 AKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVG 666 A G G G G G+ G+G Sbjct: 1127 TGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLG 1158 Score = 123 bits (309), Expect = 5e-28 Identities = 177/560 (31%), Positives = 202/560 (36%), Gaps = 75/560 (13%) Query: 179 GVKPKAPGVGGAFAGIPG-----VGPFGGPQPGVPLGY--PIKAPKLPGGYGLPYTTGKL 231 G + PG G G PG VGP G P P P G P G G P G+ Sbjct: 25 GQDVRQPGPKGQ-KGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRD 83 Query: 232 PYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVL------------ 279 PG G G G P G+G AA A K G GV+ Sbjct: 84 GEPGTPGN-PGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGP 142 Query: 280 PGVGGA-------GVPGVPGAIPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLVPGG 331 PG GA G PG PG PG+ G G G P +A K G A P G Sbjct: 143 PGPAGAPGPQGFQGNPGEPGE-PGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPG 201 Query: 332 P----GFGPGVVGVPGA----GVPGV-GVPG-AGIPVVPG-AGIPGA-AVPGVVSPEAAA 379 P GF PG G+PG G PG+ G G AG P V G +G PG PG + P Sbjct: 202 PQGARGF-PGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLP 260 Query: 380 KAAAKAAKYGARPGVGVGGIPTYGVGAGGFPG-----FGVGVGGIPGVAGVPGVGGVPGV 434 + GA G G P G G PG G G G PG G G G G Sbjct: 261 GERGRTGPAGAAGARGNDGQP----GPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGP 316 Query: 435 GGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGV 494 G G P + A GT AK +A A PG+ APG PG Sbjct: 317 EGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGA------PGIAGAPGF---PGP 367 Query: 495 GVAPGVGLAPGVGVAPGVGVAPGV-GVAPGIGPGGV--AAAAKSAAKVAAKAQLRAAAGL 551 PG A G G PG+ G GP G A + A A + R A G Sbjct: 368 RGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGE 427 Query: 552 GAGIPGLGV--GVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLG 609 G+ +G G PG G GL G PG P LA K A PG G Sbjct: 428 PGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERG-PSGLAGPKGANGDPGRPGEPG 486 Query: 610 GLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLG 669 GA G G PG AGP + A + + G G G G G +G PG G Sbjct: 487 LPGARGLTGRPG---DAGPQGKVGPSGAPGEDGRPGPPGPQGARG-QPGVMGFPGPKGAN 542 Query: 670 GIPPAAAAKAAKYGVAARPG 689 G P KA + G+ PG Sbjct: 543 GEP----GKAGEKGLPGAPG 558 Score = 110 bits (274), Expect = 6e-24 Identities = 149/461 (32%), Positives = 168/461 (36%), Gaps = 61/461 (13%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAF 82 P P G GA G G V PG A GA G G+ P P G AG Sbjct: 721 PIGPPGPAGA--NGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGP--------- 769 Query: 83 PAVTFPGAL-VPGGVADAAAAYKAAKAGA----GLGGVPGVGG-LGVSAAPSVPGAVVPQ 136 PGA PG + A + AGA G G PG G GV+ GA P Sbjct: 770 -----PGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGP- 823 Query: 137 PGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPG 196 PGA PG VG PG PG PG G P GA PG AG PG Sbjct: 824 PGATGFPGAAGRVGPPGSNGNPGPPGP--PGPSGKDG-PKGARGDSGPPGR----AGEPG 876 Query: 197 V-GPFGGP----QPGVPLGYPIKAPKLPGGY-------GLPYTTGKLPYGYGPGGVAGAA 244 + GP G P +PG + P P G GLP G+ + G G +G Sbjct: 877 LQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFP-GLPGPSGEP 935 Query: 245 GKAGYPTGTG-------VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGI 297 GK G P +G VGP A + + GA G G AGV G G + Sbjct: 936 GKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAV 995 Query: 298 GGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIP 357 G G P + A K G A P GP G G+ G P AG P Sbjct: 996 GAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEP 1055 Query: 358 VVPG----AGIPG-AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPG- 411 G G G +PG P A+ A G R G G P+ GA G PG Sbjct: 1056 GERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVG-PSGKDGANGIPGP 1114 Query: 412 FGV----GVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQA 448 G G G G AG PG G PG G PG GI A A Sbjct: 1115 IGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFA 1155 Score = 82.4 bits (202), Expect = 1e-15 Identities = 109/356 (30%), Positives = 128/356 (35%), Gaps = 47/356 (13%) Query: 363 GIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGV 422 G PG + +V P+ A + G R G G G PG G G PG Sbjct: 38 GEPGD-IKDIVGPKGPPGPQGPAGEQGPRGDRG-------DKGEKGAPG-PRGRDGEPGT 88 Query: 423 AGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGV 482 G PG G PG G PG+G + AQ A A AQ G++ G Sbjct: 89 PGNPGPPGPPGPPGPPGLGGNFAAQ---------------MAGGFDEKAGGAQLGVMQGP 133 Query: 483 GVAPGVGVAPGVGVAPGVGLAPGVGVAPG-VGVAPGVGVAPGIGPGGVAAAAKSAAKVAA 541 G PG APG G PG GV+ +G GP G A K Sbjct: 134 MGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGK 193 Query: 542 KAQLRAAAGLGA-------GIPGLGVGVGVPGLGVG---AGVPGLGVGAGVPGFGAVPG- 590 + GA G+PG+ G PGL AG PG+ +G PG PG Sbjct: 194 AGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGP 253 Query: 591 ----ALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAG----PAAAAAAAKAAAKAA 642 L + A G G G G G PG V AG P A A +A A Sbjct: 254 MGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGA 313 Query: 643 QFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPG 698 + G GA G G G G PG G G P AK G A PG +P FPG Sbjct: 314 R-GPEGAQGPRG-EPGTPGSPGPAGASGNPGTDGIPGAK-GSAGAPGIAGAPGFPG 366 >gi|116256354 alpha 2 type IV collagen preproprotein [Homo sapiens] Length = 1712 Score = 160 bits (405), Expect = 4e-39 Identities = 231/741 (31%), Positives = 289/741 (39%), Gaps = 129/741 (17%) Query: 23 PSRPG--GVPGAIPG------GVPGGV----FYPGAGLGALGGGALGPGGKPLKPVPGGL 70 P PG G PG G G+PG + F G+ AL GG GP GK P P GL Sbjct: 380 PGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGFIGDPGIPALYGGPPGPDGKRGPPGPPGL 439 Query: 71 AGA--------GL--GAGLGAFPAVT-FPGALVPGGVADAAAAYKAAKAGAGLGGVPGVG 119 G GL G FP + PGA P G A + + + G+PG+ Sbjct: 440 PGPPGPDGFLFGLKGAKGRAGFPGLPGSPGARGPKGWKGDAGECRCTEGDEAIKGLPGLP 499 Query: 120 G----LGVSAAPSVPGAVVPQPGAGVKPG-----KVPG-VGLPGVYPGGVLPGARF---P 166 G G++ P G PG PG VPG +G PG P G +R Sbjct: 500 GPKGFAGINGEPGRKGDR-GDPGQHGLPGFPGLKGVPGNIGAPG--PKGAKGDSRTITTK 556 Query: 167 GVGVLPGVPTGAGVKPK--APGVGG--AFAGIPGV------GPFGGP-QPGVPLGYPIKA 215 G PGVP G+K +PG G F G+PG GP G P PG+P Sbjct: 557 GERGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGDGIKGPPGDPGYPGIPGTKGTPG 616 Query: 216 PKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGA 275 P G GLP G+ + G G+ G G G P G Q K A G Sbjct: 617 EMGPPGLGLPGLKGQRGFP-GDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKRAVG-GDRQ 674 Query: 276 AGVLPG-VGGA-GVPGVPGAIPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGL-VPGG 331 + PG +GG G+PG+PG PG G G+ G P A A G A PG Sbjct: 675 EAIQPGCIGGPKGLPGLPGP-PGPTGAKGLRGIPGFAGADGGPGPRGLPGDAGREGFPGP 733 Query: 332 PGF-GP----GVVGVPGA-GVPG-VGVPGAGIPVVPGA-GIPGAAVPGVVSPEAAAKAAA 383 PGF GP G VG+PG G PG +G+PG P PG G+PG + P A Sbjct: 734 PGFIGPRGSKGAVGLPGPDGSPGPIGLPGPDGP--PGERGLPGEVLGAQPGPRGDA---- 787 Query: 384 KAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGIS 443 G G+ G+P G G PGF G G+PG+ G+ G G+PG G PG+ Sbjct: 788 -----GVPGQPGLKGLP----GDRGPPGFR-GSQGMPGMPGLKGQPGLPGPSGQPGLYGP 837 Query: 444 PEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLA 503 P A + +G P +PG PG PG APG Sbjct: 838 PGLHGFPGAPGQEGPLGLPG---------------IPGREGLPGDRGDPGDTGAPGPVGM 882 Query: 504 PGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVG 563 G+ G G PG PG + G+ G PGL G Sbjct: 883 KGLSGDRGDAGFTGEQGHPG-SPG-----------------FKGIDGM-PGTPGLKGDRG 923 Query: 564 VPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPG-- 621 PG+ G+PGL G PGF PG+ +A +G +PG+ G G G G G Sbjct: 924 SPGMDGFQGMPGL---KGRPGF---PGS--KGEAGFFG--IPGLKGLAGEPGFKGSRGDP 973 Query: 622 GVVGAGPAAAAAAAKAAAKAAQFGLVGAAG-LGGLGVGGL-GVPGVGGLGGIPPAAAAKA 679 G G P + G +G G LG G+ G+ G+PG+ G+ G+P Sbjct: 974 GPPGPPPVILPGMKDIKGEKGDEGPMGLKGYLGAKGIQGMPGIPGLSGIPGLPGRPGHIK 1033 Query: 680 AKYGVAARPGFGLSPIFPGGA 700 G PG P FPG A Sbjct: 1034 GVKGDIGVPGIPGLPGFPGVA 1054 Score = 149 bits (375), Expect = 1e-35 Identities = 238/846 (28%), Positives = 297/846 (35%), Gaps = 233/846 (27%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGA-------GL 75 P PG V P G PG V G +GP G P +P P G G GL Sbjct: 186 PGEPGLVGFQGPPGRPGHV------------GQMGPVGAPGRPGPPGPPGPKGQQGNRGL 233 Query: 76 G-------------AGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLG 122 G G P+ T + P GV YK K G G+ G+ G Sbjct: 234 GFYGVKGEKGDVGQPGPNGIPSDTLHPIIAPTGVTFHPDQYKGEKGSEGEPGIRGISLKG 293 Query: 123 VSAAPSVPGAVVPQPG-AGVK--PGKVPGVGLPGVY--------------PG-------- 157 PG + PG +G K PG+ GL G PG Sbjct: 294 EEGIMGFPG-LRGYPGLSGEKGSPGQKGSRGLDGYQGPDGPRGPKGEAGDPGPPGLPAYS 352 Query: 158 ---GVLPGAR----FPGVGVLP---GVPTGAGVKPKAPGV----GGAFAGIPG-VGPFGG 202 + GAR FPG P G P G+ P PG+ G G+PG +GP G Sbjct: 353 PHPSLAKGARGDPGFPGAQGEPGSQGEPGDPGL-PGPPGLSIGDGDQRRGLPGEMGPKGF 411 Query: 203 -PQPGVPLGY-----PIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV- 255 PG+P Y P PG GLP G + +G G G AG G P G Sbjct: 412 IGDPGIPALYGGPPGPDGKRGPPGPPGLPGPPGPDGFLFGLKGAKGRAGFPGLPGSPGAR 471 Query: 256 GPQAAAAAAAKAAAKFGAGAAGVLPGVGG----AGVPGVPG--------------AIPGI 297 GP+ A + G A LPG+ G AG+ G PG PG+ Sbjct: 472 GPKGWKGDAGECRCTEGDEAIKGLPGLPGPKGFAGINGEPGRKGDRGDPGQHGLPGFPGL 531 Query: 298 GGIAG-VGTPAAAAAAAAAAKAAKYGAAA--------------------GL-----VPGG 331 G+ G +G P A + G GL +PG Sbjct: 532 KGVPGNIGAPGPKGAKGDSRTITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGP 591 Query: 332 PGFG-------PGVVGVPGA-------GVPGVGVPG----------AGIPVVPG-AGIPG 366 PG G PG G+PG G PG+G+PG AG+P PG G PG Sbjct: 592 PGDGIKGPPGDPGYPGIPGTKGTPGEMGPPGLGLPGLKGQRGFPGDAGLPGPPGFLGPPG 651 Query: 367 -AAVPGVVSPEAAAKAAAKAAKYGA-RPGV-----GVGGI-----PTYGVGAGGFPGFGV 414 A PG + + K A + A +PG G+ G+ PT G G PGF Sbjct: 652 PAGTPGQIDCDTDVKRAVGGDRQEAIQPGCIGGPKGLPGLPGPPGPTGAKGLRGIPGF-A 710 Query: 415 GVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAA 474 G G PG G+PG G G G PG I P + +K VG P + Sbjct: 711 GADGGPGPRGLPGDAGREGFPGPPGF-IGP--------RGSKGAVGLPGPDGS------- 754 Query: 475 QFGLVPGVGVAPGVGVAPGVGVAPG--VGLAPGVGVAPGVGVAPGVGVAPG-IGPGGVAA 531 PG PG PG PG +G PG GV PG+ PG GP G Sbjct: 755 -----PGPIGLPGPDGPPGERGLPGEVLGAQPGPRGDAGVPGQPGLKGLPGDRGPPG--- 806 Query: 532 AAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGA 591 R + G+ G+PGL G PGL +G PGL G+ GF PG Sbjct: 807 -------------FRGSQGM-PGMPGL---KGQPGLPGPSGQPGLYGPPGLHGFPGAPG- 848 Query: 592 LAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAG 651 + +PG+ G G G G PG GP + A G G G Sbjct: 849 ------QEGPLGLPGIPGREGLPGDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGEQGHPG 902 Query: 652 LGGL-GVGGL----------GVPGVGGLGGIP--------PAAAAKAAKYGVAARPGFGL 692 G G+ G+ G PG+ G G+P P + +A +G+ G Sbjct: 903 SPGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKGRPGFPGSKGEAGFFGIPGLKGLAG 962 Query: 693 SPIFPG 698 P F G Sbjct: 963 EPGFKG 968 Score = 137 bits (345), Expect = 3e-32 Identities = 224/781 (28%), Positives = 278/781 (35%), Gaps = 159/781 (20%) Query: 26 PGGVPGAI----PGGVPGGVFYPGAGLGALGG--GALGPGGKP-LKPVPGGLAGAGLGAG 78 P G PG I P G PG PG LGA G G G G+P LK +PG G Sbjct: 751 PDGSPGPIGLPGPDGPPGERGLPGEVLGAQPGPRGDAGVPGQPGLKGLPGDRGPPGFRGS 810 Query: 79 LGAFPAVTFPGALVPGGVADAAAAYKAAKAGA----GLGGVPGVGGL-GVSAAPSVPGAV 133 G PG +PG + + G GL G PG G G P +PG Sbjct: 811 QG------MPG--MPGLKGQPGLPGPSGQPGLYGPPGLHGFPGAPGQEGPLGLPGIPGRE 862 Query: 134 VPQPGAGVKPGKV--PG-VGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVK--PKAPGVG 188 PG PG PG VG+ G+ G A F G PG P G+ P PG+ Sbjct: 863 -GLPGDRGDPGDTGAPGPVGMKGL--SGDRGDAGFTGEQGHPGSPGFKGIDGMPGTPGLK 919 Query: 189 GAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAG 248 G G PG+ F G P L G G P + G+ + +G G+ G AG+ G Sbjct: 920 GD-RGSPGMDGFQG------------MPGLKGRPGFPGSKGEAGF-FGIPGLKGLAGEPG 965 Query: 249 YPTGTG----VGPQAAAAAAAK-----------AAAKFGAGAAGV--LPGVGG-AGVPGV 290 + G GP K K GA G+ +PG+ G +G+PG+ Sbjct: 966 FKGSRGDPGPPGPPPVILPGMKDIKGEKGDEGPMGLKGYLGAKGIQGMPGIPGLSGIPGL 1025 Query: 291 PG---------------AIPGIGGIAGVGTPAAAAA----------AAAAAKAAKYGAAA 325 PG IPG+ G GV P A +A YG Sbjct: 1026 PGRPGHIKGVKGDIGVPGIPGLPGFPGVAGPPGITGFPGFIGSRGDKGAPGRAGLYGEIG 1085 Query: 326 GL-----------VPGGPGFGP--GVVGVPGA-------GVPG-VGVPG-AGIPVVPGA- 362 +PG PG G G+PG G G +G PG G+ V G Sbjct: 1086 ATGDFGDIGDTINLPGRPGLKGERGTTGIPGLKGFFGEKGTEGDIGFPGITGVTGVQGPP 1145 Query: 363 GIPG-AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPG 421 G+ G PG+ P + + + G G G G P GA G PGF G+ GI G Sbjct: 1146 GLKGQTGFPGLTGPPGSQ---GELGRIGLPGGKGDDGWP----GAPGLPGFP-GLRGIRG 1197 Query: 422 VAGVPGVGGVPG-----VGGVPGVGISP-EAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQ 475 + G+PG G PG + G PG P E A VG P + A Sbjct: 1198 LHGLPGTKGFPGSPGSDIHGDPGFPGPPGERGDPGEANTLPGPVGVPGQKGDQGAPGERG 1257 Query: 476 FGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKS 535 PG+ PG+ + APG APG+ G PG + + PG Sbjct: 1258 PPGSPGLQGFPGITPPSNISGAPGDKGAPGIFGLKGYRGPPGPPGSAAL-PGSKGDTGNP 1316 Query: 536 AAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGL--------GVG-------A 580 A + A G PG+ G+PG G G VG Sbjct: 1317 GAPGTPGTKGWAGDSGPQGRPGV---FGLPGEKGPRGEQGFMGNTGPTGAVGDRGPKGPK 1373 Query: 581 GVPGFGAVPGALAAAKAAKYG---AAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKA 637 G PGF PG + A A A PG +G G G G PG + GP A Sbjct: 1374 GDPGFPGAPGTVGAPGIAGIPQKIAVQPGTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGA 1433 Query: 638 AAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFP 697 KA G G GG+ VPG G G P + G RPG SP P Sbjct: 1434 PGKA------GPQGRGGVS----AVPGFRGDEG-PIGHQGPIGQEGAPGRPG---SPGLP 1479 Query: 698 G 698 G Sbjct: 1480 G 1480 Score = 113 bits (283), Expect = 5e-25 Identities = 185/652 (28%), Positives = 226/652 (34%), Gaps = 81/652 (12%) Query: 92 VPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVVPQPGAGVKPGKVPGVGL 151 VP G D + + G G VG G + P + G PG + G G Sbjct: 40 VPCGGRDCSGGCQCYPEKGGRGQPGPVGPQGYNGPPGLQGF----PGLQGRKGDKGERGA 95 Query: 152 PGVYPGGVLPGAR----FPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGV 207 PGV GAR FPG +PG P G + + PG G GP G P Sbjct: 96 PGVTGPKGDVGARGVSGFPGADGIPGHPGQGGPRGR-PGYDGCNGTQGDSGPQGPPGSEG 154 Query: 208 PLGYPIKAPKLPGGY-GLPYTTGKLP---YGYGPG--GVAGAAGKAGYPTGTG-VGPQAA 260 G P P+ P G G PY K Y PG G+ G G G P G +GP A Sbjct: 155 FTGPP--GPQGPKGQKGEPYALPKEERDRYRGEPGEPGLVGFQGPPGRPGHVGQMGPVGA 212 Query: 261 AAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAI--PGIGGIAGVGTPAAAAAAAAAAKA 318 G G G+G GV G G + PG GI A Sbjct: 213 PGRPGPPGPPGPKGQQGNR-GLGFYGVKGEKGDVGQPGPNGIPSDTLHPIIAPTGVTFHP 271 Query: 319 AKYGAAAGLVPGGPGFGPGVVGVPGAGVPGV-GVPGA-GIPVVPGA-GIPGA----AVPG 371 +Y G PG+ G+ G G+ G PG G P + G G PG + G Sbjct: 272 DQYKGEKGSEGE-----PGIRGISLKGEEGIMGFPGLRGYPGLSGEKGSPGQKGSRGLDG 326 Query: 372 VVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGV 431 P+ +A G P+ GA G PGF PG G PG G Sbjct: 327 YQGPDGPRGPKGEAGDPGPPGLPAYSPHPSLAKGARGDPGF-------PGAQGEPGSQGE 379 Query: 432 PGVGGVPG-----VGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAP 486 PG G+PG +G + + K +G P A +G PG Sbjct: 380 PGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGFIGDPGIPAL--------YGGPPGPDGKR 431 Query: 487 GVGVAPGVGVAPGV-GLAPGVGVAPGVGVAPGVGVAPGI-GPGGVAAAAKSAAKVAAKAQ 544 G PG+ PG G G+ A G PG+ +PG GP G A Sbjct: 432 GPPGPPGLPGPPGPDGFLFGLKGAKGRAGFPGLPGSPGARGPKGWKGDAGECRCTEGDEA 491 Query: 545 LRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAA--AKAAKYGA 602 ++ GL G G G PG G PG G PG VPG + A K AK + Sbjct: 492 IKGLPGL-PGPKGFAGINGEPGRKGDRGDPGQHGLPGFPGLKGVPGNIGAPGPKGAKGDS 550 Query: 603 AV---------PGVLGGLGALGGVGIPG-----GVVGAGPAAAAAAAKAAAKAAQFGLVG 648 PGV G G G G PG G G G+ G Sbjct: 551 RTITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGDGIKGPPGDPGYPGIPG 610 Query: 649 AAGL-GGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPGG 699 G G +G GLG+PG+ G G P A G+ PGF L P P G Sbjct: 611 TKGTPGEMGPPGLGLPGLKGQRGFPGDA-------GLPGPPGF-LGPPGPAG 654 Score = 106 bits (264), Expect = 9e-23 Identities = 154/492 (31%), Positives = 190/492 (38%), Gaps = 101/492 (20%) Query: 23 PSRPGGVPGA-----IPGGVPGGVFYPG-AGLGALGG--GALGPGGKPLKPVPGGLAGAG 74 P RPG + G +PG +PG +PG AG + G G +G G P GL G Sbjct: 1026 PGRPGHIKGVKGDIGVPG-IPGLPGFPGVAGPPGITGFPGFIGSRGDKGAPGRAGLYGE- 1083 Query: 75 LGAGLGAF----PAVTFPGALVPG--------GVADAAAAY--KAAKAGAGLGGVPGVGG 120 +GA G F + PG PG G+ + K + G G+ GV G Sbjct: 1084 IGA-TGDFGDIGDTINLPGR--PGLKGERGTTGIPGLKGFFGEKGTEGDIGFPGITGVTG 1140 Query: 121 L----GVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPT 176 + G+ PG P PG+ G++ +GLPG PGA PG LPG P Sbjct: 1141 VQGPPGLKGQTGFPGLTGP-PGS---QGELGRIGLPGGKGDDGWPGA--PG---LPGFPG 1191 Query: 177 GAGVKPK--APGVGGAFAGIPGVGPFGGPQ-PGVP--LGYPIKAPKLPGGYGLPYTTGK- 230 G++ PG G F G PG G P PG P G P +A LPG G+P G Sbjct: 1192 LRGIRGLHGLPGTKG-FPGSPGSDIHGDPGFPGPPGERGDPGEANTLPGPVGVPGQKGDQ 1250 Query: 231 -LPYGYGPGG---------------VAGAAGKAGYPTGTGV----GPQAAAAAAAKAAAK 270 P GP G ++GA G G P G+ GP +AA +K Sbjct: 1251 GAPGERGPPGSPGLQGFPGITPPSNISGAPGDKGAPGIFGLKGYRGPPGPPGSAALPGSK 1310 Query: 271 FGAGAAGV--LPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLV 328 G G PG G P PG+ G+ G P GA Sbjct: 1311 GDTGNPGAPGTPGTKGWAGDSGPQGRPGVFGLPGEKGPRGEQGFMG--NTGPTGAVGDRG 1368 Query: 329 PGGPGFGPGVVGVPGAGVPGVGVPG-AGIP----VVPGA-------GIPGAAVPGVVSPE 376 P GP PG G PG VG PG AGIP V PG G PGA PG + P+ Sbjct: 1369 PKGPKGDPGFPGAPGT----VGAPGIAGIPQKIAVQPGTVGPQGRRGPPGA--PGEMGPQ 1422 Query: 377 AAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFG-----VGVGGIPGVAGVPGVGGV 431 + G R G G G G PGF +G G G G PG G Sbjct: 1423 GPP------GEPGFRGAPGKAGPQGRG-GVSAVPGFRGDEGPIGHQGPIGQEGAPGRPGS 1475 Query: 432 PGVGGVPGVGIS 443 PG+ G+PG +S Sbjct: 1476 PGLPGMPGRSVS 1487 Score = 62.4 bits (150), Expect = 1e-09 Identities = 95/308 (30%), Positives = 110/308 (35%), Gaps = 58/308 (18%) Query: 23 PSRPGGVPGAIPG--GVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLG 80 P PG PG G PG PG L G PG K + PG G GL Sbjct: 1208 PGSPGSDIHGDPGFPGPPGERGDPGEA-NTLPGPVGVPGQKGDQGAPGERGPPG-SPGLQ 1265 Query: 81 AFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGL-GVSAAPSVPGAVVPQPGA 139 FP +T P + + G D G PG+ GL G P PG+ PG+ Sbjct: 1266 GFPGIT-PPSNISGAPGDK--------------GAPGIFGLKGYRGPPGPPGSAA-LPGS 1309 Query: 140 GVKPGKVPGVGLPGV--YPGGVLPGARFPGVGVLPGV--------------PTGA--GVK 181 G G PG + G P R PGV LPG PTGA Sbjct: 1310 KGDTGNPGAPGTPGTKGWAGDSGPQGR-PGVFGLPGEKGPRGEQGFMGNTGPTGAVGDRG 1368 Query: 182 PKAPGVGGAFAGIPG-VGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV 240 PK P F G PG VG PG+ G P K PG G G P G G Sbjct: 1369 PKGPKGDPGFPGAPGTVGA-----PGIA-GIPQKIAVQPGTVGPQGRRGP-PGAPGEMGP 1421 Query: 241 AGAAGKAGYPTGTG-VGPQAAAAAAAKAAAKFGAGAAGV--------LPG-VGGAGVPGV 290 G G+ G+ G GPQ +A + G G PG G G+PG+ Sbjct: 1422 QGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGDEGPIGHQGPIGQEGAPGRPGSPGLPGM 1481 Query: 291 PGAIPGIG 298 PG IG Sbjct: 1482 PGRSVSIG 1489 Score = 45.4 bits (106), Expect = 2e-04 Identities = 116/443 (26%), Positives = 132/443 (29%), Gaps = 107/443 (24%) Query: 344 AGVPGVGVPGAG---------IPVVPGAGIPGAAVP----GVVSPEAAAKAAAKAAKYGA 390 AGV VP G P G G PG P G + + G Sbjct: 33 AGVKKFDVPCGGRDCSGGCQCYPEKGGRGQPGPVGPQGYNGPPGLQGFPGLQGRKGDKGE 92 Query: 391 RPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGV-------GIS 443 R GV G P VGA G GF PG G+PG G G G PG G S Sbjct: 93 RGAPGVTG-PKGDVGARGVSGF-------PGADGIPGHPGQGGPRGRPGYDGCNGTQGDS 144 Query: 444 --------------PEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLV-----PG--- 481 P Q K Y + P + + + GLV PG Sbjct: 145 GPQGPPGSEGFTGPPGPQGPKGQKGEPYAL--PKEERDRYRGEPGEPGLVGFQGPPGRPG 202 Query: 482 -VGVAPGVGVAPGVGVAPG------------------VGLAPGVGVAPGVGVAPGVGVAP 522 VG VG APG PG G VG PG P + P Sbjct: 203 HVGQMGPVG-APGRPGPPGPPGPKGQQGNRGLGFYGVKGEKGDVG-QPGPNGIPSDTLHP 260 Query: 523 GIGPGGV--------------------AAAAKSAAKVAAKAQLRAAAGLGA--GIPGLGV 560 I P GV + K + LR GL G PG Sbjct: 261 IIAPTGVTFHPDQYKGEKGSEGEPGIRGISLKGEEGIMGFPGLRGYPGLSGEKGSPGQKG 320 Query: 561 GVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIP 620 G+ G G G AG PG +P AK PG G G G G P Sbjct: 321 SRGLDGYQGPDGPRGPKGEAGDPGPPGLPAYSPHPSLAKGARGDPGFPGAQGEPGSQGEP 380 Query: 621 GGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAA 680 G GP + + GL G G G +G PG+ L G PP K Sbjct: 381 GDPGLPGPPGLSIGDGDQRR----GLPGEMGPKGF----IGDPGIPALYGGPPGPDGKRG 432 Query: 681 KYGVAARPGFGLSPIFPGGACLG 703 G PG P P G G Sbjct: 433 PPGPPGLPG----PPGPDGFLFG 451 >gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] Length = 1499 Score = 153 bits (387), Expect = 5e-37 Identities = 234/756 (30%), Positives = 266/756 (35%), Gaps = 123/756 (16%) Query: 28 GVPGAI-PGGVPGGVFYPG-AGLGALGG--GALGPGGK--------PLKPVPG-GLAGA- 73 G PG + P G+PG +PG G+ G GA GP G P PV GL GA Sbjct: 363 GKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAI 422 Query: 74 GLGAGLGAFPAVTFPGALVPGGVADAAAA-----YKAAKAGAGLGGVPGVGGLGVSAAPS 128 G GA PG P G A + + G G PGV G A P Sbjct: 423 GTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPK 482 Query: 129 -------VPGAVVPQPGAGVK-PGKVPG-VGLPGVYPGGVLPGAR-FPGVGVLPGVPTGA 178 + G + P G + P PG VG PG PG R FPG LPG P GA Sbjct: 483 GEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPG-PKGA 541 Query: 179 ----------GVK--------PKAPGVGGA--FAGIPGV-------GPFGGP----QPGV 207 G K P PG+ GA G PGV GP G P +PG Sbjct: 542 QGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGP 601 Query: 208 PLGYPIKAPKLPGGYGLPYTTGKL--PYGYGPGGVAGAAGKAGYPTGTG-VGPQAAAAAA 264 P I+ PG GLP G P G G AG G+ G P G VGP Sbjct: 602 PGSIGIRGQ--PGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPP 659 Query: 265 AKAAAKFGAGAAGVL-----------PGVGGA----GVPGVPGAIPGIGGIAGVGTPAAA 309 A + G G PG GG GVPG PGA+ +G G P Sbjct: 660 GLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGER 719 Query: 310 AAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AGVPGV-GVPG-AGIPVVPG----- 361 + G A G P GP PG G PG G PG+ G+PG GI PG Sbjct: 720 GEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDR 779 Query: 362 -----------AGIPGA-AVPGVVSPEAAAKAAAKAAKYGARPGVG-VGGIPTYGVGAGG 408 AG GA +PG + P A + + G R VG G G Sbjct: 780 GGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGEN 839 Query: 409 FPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAK 468 P VG G G G PGV G PG G G SP Q A + G P + Sbjct: 840 GPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGR 899 Query: 469 AAAKAAQFGLVPG----VGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGV-GVAPG 523 PG VG PG APG G PG PG+ PG G Sbjct: 900 GTQGPPGATGFPGSAGRVG-PPGPAGAPGPAGPLG---EPGKEGPPGLRGDPGSHGRVGD 955 Query: 524 IGPGGVAAAAKSAAKVAAKAQLRAAAGLG-AGIPGLGVGVGVPGLGVGAGVPGLGVGAGV 582 GP G Q G AG G VG+PG G+PGL AG Sbjct: 956 RGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGT 1015 Query: 583 PGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAA 642 PG GA PG +G G+ G VG PG AG A + Sbjct: 1016 PGKVGPTGATG-------DKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERG 1068 Query: 643 QFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAK 678 G G AGL G G PG G G P A + Sbjct: 1069 DRGDPGPAGL----PGSQGAPGTPGPVGAPGDAGQR 1100 Score = 137 bits (344), Expect = 4e-32 Identities = 230/753 (30%), Positives = 264/753 (35%), Gaps = 143/753 (18%) Query: 26 PGGVPGAI--PG-----GVPGGVFYPGA-GL----GALG-------GGALGPGGKPLKPV 66 P G PG + PG G PG +PG+ GL GA G G G G P +P Sbjct: 505 PRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPG 564 Query: 67 PGGLAGAGLGAGLGAFPAVTFP-GALVPGGVADAAAAYKAAKAGAGLGGVPGVGGL---- 121 GL GA GL P V P G L P G A G+ G PG GL Sbjct: 565 EPGLPGA---RGLTGNPGVQGPEGKLGPLG-APGEDGRPGPPGSIGIRGQPGSMGLPGPK 620 Query: 122 GVSAAPSVPGAV--VPQPGAGVKPGKVPGVGLPGVYPGGVLPGAR----------FPGVG 169 G S P PG PG PGK VG G L G R F G+ Sbjct: 621 GSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLP 680 Query: 170 VLPGVPTGAGVKPKAPGVGGAFAGIPG-VGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTT 228 PG P G G KP GV G PG VGP G P G P + + PG GLP Sbjct: 681 GPPG-PPGEGGKPGDQGVPGD----PGAVGPLG---PRGERGNPGERGE-PGITGLPGEK 731 Query: 229 GKLPYGYGPGGVAGAAGKAGYPTGTGV-------GPQAAAAAAAKAAAKFGAGAAGVLPG 281 G + G+GP G G+ G +G P TG G + A + G G G Sbjct: 732 G-MAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGT 790 Query: 282 VGGAGVPGVPGAI--PGIGGIAG----------VGTPAAAAAAAAAAKAAKYGAAAGLVP 329 G G G+PG + PG G G VG P + + + GA P Sbjct: 791 AGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGP 850 Query: 330 GGPGFGPGVVGVPG----------------AGVPGV----GVPGA----GIPVVPGA-GI 364 GP PGV G PG AG PG GVPG G PGA G Sbjct: 851 QGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGF 910 Query: 365 PGAAVPGVVSPEAAAKAAAKAAKYGARPGV----GVGGIP-TYGV----GAGGFPGFGVG 415 PG+A G V P A A A G PG G+ G P ++G G G PG G G Sbjct: 911 PGSA--GRVGPPGPAGAPGPAGPLG-EPGKEGPPGLRGDPGSHGRVGDRGPAGPPG-GPG 966 Query: 416 VGGIPGVAGVPGVGGVPGVGGVPGV-GISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAA 474 G PG G PG G PG G G GI + G+ PA K A Sbjct: 967 DKGDPGEDGQPGPDGPPGPAGTTGQRGIV--GMPGQRGERGMPGLPGPAGTPGKVGPTGA 1024 Query: 475 QFGLVPGVGVAP----GVGVAPGVGVAPGVGLAPGVGVA---------PGVGVAPGVGVA 521 P V P G PG G PG A PG PG A Sbjct: 1025 TGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGA 1084 Query: 522 PGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAG 581 PG PG V A + + G PG +G PG G+PG G Sbjct: 1085 PGT-PGPVGAPGDAGQR---------------GDPGSRGPIGPPGRAGKRGLPGPQGPRG 1128 Query: 582 VPGFGAVPGALAAAKAAKYGA--AVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAA 639 G G + +PG G G G GIPG GP + Sbjct: 1129 DKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEG 1188 Query: 640 KAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIP 672 G +G G+ G VG G G G G P Sbjct: 1189 NPGPLGPIGPPGVRG-SVGEAGPEGPPGEPGPP 1220 Score = 127 bits (318), Expect = 5e-29 Identities = 212/716 (29%), Positives = 244/716 (34%), Gaps = 111/716 (15%) Query: 44 PGAGLGALGGGALGPGGKP-LKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAA 102 PG G G G G G+P L PV G+ G AG PG+ P G Sbjct: 100 PGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGP--------PGSQGPRGERGPKGR 151 Query: 103 YKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVV-PQPGAGVKPGKVPGVGLP--------- 152 + G+ G PGV G AP PG P P +P GL Sbjct: 152 -PGPRGPQGIDGEPGVPGQ--PGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQV 208 Query: 153 GVYPGGVLP-GARFPGVGVLPGVPTGAGVK--PKAPGVGGAFAGIPGVGPFGGP------ 203 G+ PG V P G R P L G GAG P PG G I GP G P Sbjct: 209 GLMPGSVGPVGPRGPQG--LQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGED 266 Query: 204 -QPG-------VPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTG- 254 +PG V A PG GLP G G G+ G G+ G P G Sbjct: 267 GEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHR----GHKGLEGPKGEVGAPGSKGE 322 Query: 255 VGPQAAAAAAAKAAAKFGAGAAGVL-----PGVGGA-GVPGVPG-----AIPGIGGIAG- 302 GP A + G G L PG GA G+PG PG IPG G G Sbjct: 323 AGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGN 382 Query: 303 VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPG----VGVPGAGIP 357 G A A G P GP PG+ G G G PG G PG P Sbjct: 383 PGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGP 442 Query: 358 VVPG-AGIPGAAVP-GVVSPEAAAKAAAKAAKYGARPGVGVGGIP-TYGV---------- 404 PG AG PG+ P G P+ G + G G P +G+ Sbjct: 443 --PGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEE 500 Query: 405 ---GAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGT 461 G G PG VG G G G PG G PG G+PG + + + K G Sbjct: 501 GKRGPRGDPG-TVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGD 559 Query: 462 PAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVA 521 P A GL GV G +G APG PG + G+ PG Sbjct: 560 PGRPGEPGLPGAR--GLTGNPGVQGPEGKLGPLG-APGEDGRPGPPGSIGIRGQPGSMGL 616 Query: 522 PG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGA 580 PG G G A Q R A G G G VG PGL AG G Sbjct: 617 PGPKGSSGDPGKPGEAGNAGVPGQ-RGAPGKD-GEVGPSGPVGPPGL---AGERGEQGPP 671 Query: 581 GVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAK 640 G GF +PG PG G G G G+PG GP + Sbjct: 672 GPTGFQGLPGP-------------PGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGE 718 Query: 641 AAQFGLVGAAG----LGGLGVGG-LGVPGVGGLGGI--PPAAAAKAAKYGVAARPG 689 + G+ G G GG G G G PG G G PP + G+A PG Sbjct: 719 RGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPG 774 Score = 99.8 bits (247), Expect = 8e-21 Identities = 149/499 (29%), Positives = 175/499 (35%), Gaps = 95/499 (19%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGA-GLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGA 81 P P G PG P G PG PG G+ G A PG K + GG+ G G Sbjct: 739 PDGPKGSPG--PSGTPGDTGPPGLQGMPGERGIAGTPGPKGDR---GGIGEKGAEGTAGN 793 Query: 82 FPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGL-------GVSAAPSVPGAVV 134 A PG L P G A K GL G PG G G + A G Sbjct: 794 DGARGLPGPLGPPGPAGPTGE-KGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQG 852 Query: 135 PQPGAGVK-----PGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVK--PKAPGV 187 P GVK PG+ G PG P G+ G +PG+ G G + P A G Sbjct: 853 PDGQPGVKGEPGEPGQKGDAGSPG--PQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGF 910 Query: 188 GGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKA 247 G+ + GP G P P PLG P K PG G P + G++ GP G G G Sbjct: 911 PGSAGRVGPPGPAGAPGPAGPLGEPGKEGP-PGLRGDPGSHGRVG-DRGPAGPPGGPGDK 968 Query: 248 GYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGV-----LPGVGG-AGVPGV---------- 290 G P G GP A + G G +PG+ G AG PG Sbjct: 969 GDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDK 1028 Query: 291 --PGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA---- 344 PG + G VG P A + GA G PG G+PG+ Sbjct: 1029 GPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVG---ERGDRGDPGPAGLPGSQGAP 1085 Query: 345 GVPG-VGVPG-AGIPVVPGA----GIPGAA----VPGVVSPEAAAKAAAKAAKYGARPGV 394 G PG VG PG AG PG+ G PG A +PG P G + Sbjct: 1086 GTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHR 1145 Query: 395 GVGGI--------PTYGVGAGGFPG-FGV-------------------------GVGGIP 420 G G+ P G+ G PG FG GV G Sbjct: 1146 GFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSV 1205 Query: 421 GVAGVPGVGGVPGVGGVPG 439 G AG G G PG G PG Sbjct: 1206 GEAGPEGPPGEPGPPGPPG 1224 Score = 80.5 bits (197), Expect = 5e-15 Identities = 129/409 (31%), Positives = 145/409 (35%), Gaps = 63/409 (15%) Query: 23 PSRPGGVPGAIPG----GVPGGVFYPGAGLGALGG-------GALGPGGKPLKPVPGGLA 71 P P GVPG G G PG +PG+ G +G G GP G+P K P GL Sbjct: 886 PHGPNGVPGLKGGRGTQGPPGATGFPGSA-GRVGPPGPAGAPGPAGPLGEPGKEGPPGLR 944 Query: 72 G-AGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAG----AGLGGVPGVGGL-GVSA 125 G G +G PG PG D + G AG G G+ G+ G Sbjct: 945 GDPGSHGRVGDRGPAGPPGG--PGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRG 1002 Query: 126 APSVPGAVVPQPGAGVKPGKVPGVGLPGVY--PGGVLPGARFPGVGVLPGVPTGAGVKPK 183 +PG PG PGKV G G PG V P VG PG P G Sbjct: 1003 ERGMPGL----PGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGE-PG-PEGPAGNDG 1056 Query: 184 APGVGGAFAGIPGVGPFGGPQPGVPLGYPIK--APKLPGGYGLPYTTGKL--PYGYGPGG 239 PG GA VG G P G P AP PG G P G+ P GP G Sbjct: 1057 TPGRDGA------VGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIG 1110 Query: 240 VAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGG 299 G AGK G P GPQ + G G G G+ G+PG PG G Sbjct: 1111 PPGRAGKRGLP-----GPQGPRGDKGDHGDRGDRGQKGHR---GFTGLQGLPGP-PGPNG 1161 Query: 300 IAG-VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPV 358 G G P G P GP PGV G G P G PG P Sbjct: 1162 EQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGP-EGPPGEPGPP 1220 Query: 359 VPGAGIPG---AAVPGVVS----------PEAAAKAAAKAAKYGARPGV 394 P G PG AA+ ++ PE AA K PGV Sbjct: 1221 GP-PGPPGHLTAALGDIMGHYDESMPDPLPEFTEDQAAPDDKNKTDPGV 1268 Score = 70.1 bits (170), Expect = 7e-12 Identities = 113/378 (29%), Positives = 135/378 (35%), Gaps = 69/378 (18%) Query: 330 GGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGA-GIPGAAVPGVVSPEAAAKAAAKAAKY 388 G FG G G G PG+ +PVV G G PG A P P + + K Sbjct: 103 GNTNFGRGRKGQKGE--PGL------VPVVTGIRGRPGPAGP----PGSQGPRGERGPK- 149 Query: 389 GARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGV-GISPEAQ 447 RPG P G+ G PGV G PG G PG PG G+S Sbjct: 150 -GRPG----------------PRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFS 192 Query: 448 AAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVG 507 A A K G+G+ Q GL+PG V P VG GL G Sbjct: 193 AQMAGLDEKSGLGS-------------QVGLMPG-------SVGP-VGPRGPQGLQGQQG 231 Query: 508 VAPGVGVAPGVGVAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLG----AGIPGLGVGV 562 A G PG PG +GP G K + G AG PG Sbjct: 232 GAGPTG-PPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFP 290 Query: 563 GVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGG 622 G PGL PGL G G G + A +K A G +G +G LG G+PG Sbjct: 291 GAPGL------PGLKGHRGHKGLEGPKGEVGAP-GSKGEAGPTGPMGAMGPLGPRGMPGE 343 Query: 623 VVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKA--A 680 GP A A + G +G G+ G G G PG+ G G A + Sbjct: 344 RGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPG-SSGFPGNPGMKGEAGPTGARGPEGPQG 402 Query: 681 KYGVAARPGFGLSPIFPG 698 + G PG SP PG Sbjct: 403 QRGETGPPGPVGSPGLPG 420 >gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] Length = 1626 Score = 150 bits (378), Expect = 5e-36 Identities = 224/767 (29%), Positives = 273/767 (35%), Gaps = 116/767 (15%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGG--GALGPGGKPLKPVPGGLAGA------- 73 P PG G PG + PG L G G GP G P P P G GA Sbjct: 538 PGPPGRDGSKGMRGEPGELGEPG-----LPGEVGMRGPQGPPGLPGPPGRVGAPGLQGER 592 Query: 74 ---GLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPG-VGGLGVSAAPSV 129 G G FPG PG + +G+ G G G +G + P V Sbjct: 593 GEKGTRGEKGERGLDGFPGK--PGDTGQ-----QGRPGPSGVAGPQGEKGDVGPAGPPGV 645 Query: 130 PGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFP-GVGVLPGVPTGAGVKPKAPGVG 188 PG+VV Q G + G G G PG PGAR P G G P G++ K +G Sbjct: 646 PGSVVQQEGLKGEQGAPGPRGHQGA-PGP--PGARGPIGPEGRDGPPGLQGLRGKKGDMG 702 Query: 189 GAFAGIPGVGPFGGP--QPGVP-LGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAG 245 GIPG+ GP PGVP P +P LPG G P G P GP G G G Sbjct: 703 P--PGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGP-PGPTGPPGKDGPNG 759 Query: 246 KAGYPTGTG-VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAG-V 303 G P G G + K + G G+ G G G+PGA PG G+ G Sbjct: 760 PPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGA-PGFPGVRGEK 818 Query: 304 GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPG---------- 353 G G P GP PG+ G P +PG Sbjct: 819 GDQGEKGELGLPGLKGDRGEKGEAGPAGP---PGLPGTTSLFTPHPRMPGEQGPKGEKGD 875 Query: 354 AGIPVVPG-AGIPG-------AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVG 405 G+P PG G PG PG E A A A GA VG G P+ G Sbjct: 876 PGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPG-PSGPPG 934 Query: 406 AGGFPGF--------------GVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAA 451 + G PG G G PG G G G PG+ G PG G E Sbjct: 935 SVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGE-PGLRG 993 Query: 452 AKAAKYGVGTPAAAAAKAAAKAAQFG--LVPGVGVAPGVGVAPGVGVAPGVGLA--PGVG 507 + +GT AA ++ G V G APG+ +PG PG+G+A PG Sbjct: 994 SPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPS 1053 Query: 508 VAPGVGVAPGVGVAPGI----GPGGVAAAAKSAAK--VAAKAQLRAAAGLG--------- 552 PG +PG PG GP G A + + K L + G Sbjct: 1054 GPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDV 1113 Query: 553 -----------AGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYG 601 G+PG GVPG G G AG PG PG +A + ++ Sbjct: 1114 CNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPG-IAGPQGSQGE 1172 Query: 602 AAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGL----GGLGV 657 G +G G G G+PG + G A A A G+ G+ G G G Sbjct: 1173 RGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGP 1232 Query: 658 GGL-GVPGVGGLGGI-----PPAAAAKAAKYGVAARPGFGLSPIFPG 698 GL G+PG G G PP KA + G+ G P F G Sbjct: 1233 SGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKG 1279 Score = 147 bits (370), Expect = 4e-35 Identities = 209/735 (28%), Positives = 259/735 (35%), Gaps = 96/735 (13%) Query: 23 PSRPGGVPGAI--------PGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAG 74 P+ P GVPG++ G PG + GA G +GP G+ P GL G Sbjct: 639 PAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKK 698 Query: 75 LGAGLGAFPAVT-FPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG-LGVSAAPSVPGA 132 G P + G P GV G GG PG+ G +G P PG Sbjct: 699 GDMGPPGIPGLLGLQGPPGPPGVPGPP----------GPGGSPGLPGEIGFPGKPGPPGP 748 Query: 133 VVPQ-----------PGAGVKPGKVPGVGLPGVYPG--------GVLPGARFPGVGVLPG 173 P PG +PG+ GLPG PG G+ G LPG Sbjct: 749 TGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGK-PGLRGEIGEQGLAGRPGEKGEAGLPG 807 Query: 174 VPTGAGVKPKAPGVGG-AFAGIPGV-GPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKL 231 P GV+ + G G+PG+ G G P G P LPG L ++ Sbjct: 808 APGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAG----PPGLPGTTSLFTPHPRM 863 Query: 232 PYGYGPGGVAGAAGKAGYPTGTG-------VGPQAAAAAAAKAAAKFGAGAAGVLPGVGG 284 P GP G G G G P G GP A + A GAAG G Sbjct: 864 PGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGH 923 Query: 285 AGVPGVPGAIPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG 343 G PG P PG G G+ GTP A + G+ + P G PG+ G PG Sbjct: 924 VGAPG-PSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPG 982 Query: 344 AGVPGVGVPG-AGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTY 402 G G PG G P +PG + A G V + K G R G+ G P Sbjct: 983 KGKD--GEPGLRGSPGLPGP-LGTKAACGKVRGSENCALGGQCVK-GDRGAPGIPGSP-- 1036 Query: 403 GVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGV-GT 461 G+ G P G+GV G PG +G PG G PG G+PG P+ A G G Sbjct: 1037 --GSRGDP--GIGVAGPPGPSGPPGDKGSPGSRGLPGFP-GPQGPAGRDGAPGNPGERGP 1091 Query: 462 PAAAAAKAAAKAAQFGLV---------PGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGV 512 P + L+ PG PG+ PG GV PG G Sbjct: 1092 PGKPGLSSLLSPGDINLLAKDVCNDCPPG---PPGLPGLPGFKGDKGV---PGKPGREGT 1145 Query: 513 GVAPGVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRAAAGLG-AGIPGLGVGVGVPGLGVG 570 G PG+ GP G+A S + A ++ G G+PG +G PG Sbjct: 1146 EGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGF---MGPPGNPGP 1202 Query: 571 AGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAA 630 G G+ AG PG PG + + +PG+ G G G G PG G A Sbjct: 1203 PGADGIAGAAGPPGIQGSPGK-EGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAG 1261 Query: 631 AAAAAKAAAKAAQFGLVGAAGLGGL-----GVGGLGVPGVGGLGGI--PPAAAAKAAKYG 683 G G G G G +G+PG GL G G Sbjct: 1262 EPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQG 1321 Query: 684 VAARPGFGLSPIFPG 698 PG SP PG Sbjct: 1322 PRGPPGKNGSPGSPG 1336 Score = 134 bits (337), Expect = 3e-31 Identities = 209/718 (29%), Positives = 248/718 (34%), Gaps = 117/718 (16%) Query: 59 GGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPG---GVADAAAAYKAAKAGAGLGGV 115 G K V G + G +GA V PG G+ K K GL G Sbjct: 481 GEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGP 540 Query: 116 PGVGGL-------GVSAAPSVPGAV---VPQ--PGAGVKPGKVPGVGLPGVYPGGVLPGA 163 PG G G P +PG V PQ PG PG+V GL G G Sbjct: 541 PGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGE 600 Query: 164 RFP-GVGVLPGVP--TGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPG 220 + G+ PG P TG +P GV G VGP G PGVP G ++ L G Sbjct: 601 KGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAG--PPGVP-GSVVQQEGLKG 657 Query: 221 GYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLP 280 G P G G G GA G G P G GP K G G+L Sbjct: 658 EQGAPGPRGH----QGAPGPPGARGPIG-PEGRD-GPPGLQGLRGKKGDMGPPGIPGLLG 711 Query: 281 GVGGAGVPGVPGAIPGIGGIAG----VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGP 336 G G PGVPG PG GG G +G P K G P GP P Sbjct: 712 LQGPPGPPGVPGP-PGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDG------PNGPPGPP 764 Query: 337 GVVGVPGA----GVPG-------VGVPG-AGIPVVPG-AGIPGA-AVPGVVSPEAAAKAA 382 G G PG G+PG +G G AG P G AG+PGA PGV + Sbjct: 765 GTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEK 824 Query: 383 AKAAKYGARPGVGVGGIPTYGVGAGGFPGF---------------GVGVGGIPGVAGVPG 427 + G + G G G G PG G G PG+ G PG Sbjct: 825 GELGLPGLKGDRGEKG-EAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPG 883 Query: 428 VGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPG 487 + G PG G G P A+ A A G P A A PG PG Sbjct: 884 LQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGA---------PGPSGPPG 934 Query: 488 VGVAPGVGVAPG-------------------VGL-----APGVGVAPGVGV--APGVGVA 521 APG+ PG VG APG+ PG G PG+ + Sbjct: 935 SVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGS 994 Query: 522 PGI-GPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGA 580 PG+ GP G AA + A G G + G G+PG G PG+GV A Sbjct: 995 PGLPGPLGTKAACGK-----VRGSENCALG-GQCVKGDRGAPGIPGSPGSRGDPGIGV-A 1047 Query: 581 GVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAK 640 G PG PG K + +PG G G G G PG GP + + Sbjct: 1048 GPPGPSGPPG----DKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLS-SLLS 1102 Query: 641 AAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPG 698 L+ G G+PG+ G G K + G + G P PG Sbjct: 1103 PGDINLLAKDVCNDCPPGPPGLPGLPGFKG-DKGVPGKPGREGTEGKKGEAGPPGLPG 1159 Score = 118 bits (295), Expect = 2e-26 Identities = 219/740 (29%), Positives = 258/740 (34%), Gaps = 107/740 (14%) Query: 22 HPSRPGGVPGAIPGGVPGGVFYPGA-GLGALGG-----GALGPGGKPLKPVPGGLAGA-G 74 +P PG V P G PG V PG G G GA G G P P G GA G Sbjct: 917 NPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPG 976 Query: 75 L----GAGLGAFPAVT-FPGALVPGGVADAAAAYKA-AKAGAGLGGVPGVGGLGVSAAPS 128 L G G P + PG +PG + AA K LGG G G P Sbjct: 977 LPGPPGKGKDGEPGLRGSPG--LPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPG 1034 Query: 129 VPGAVVPQPGAGVK--PGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPG 186 PG+ PG GV PG G G LPG FPG P P G P PG Sbjct: 1035 SPGSR-GDPGIGVAGPPGPSGPPGDKGSPGSRGLPG--FPG----PQGPAGRDGAPGNPG 1087 Query: 187 VGGAFAGIPGVGPFGGPQP----------GVPLGYPIKAPKLPGGYGLPYTTGKLPYGYG 236 G G PG+ P P G P P LPG G GK P G Sbjct: 1088 ERGP-PGKPGLSSLLSPGDINLLAKDVCNDCPPGPP-GLPGLPGFKGDKGVPGK-PGREG 1144 Query: 237 PGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGG-AGVPGVPGAIP 295 G G AG G P G+ + A + G PGV G G PG PG P Sbjct: 1145 TEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGP-P 1203 Query: 296 GIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGL--VPG-----------GPGFGPGVVGVP 342 G GIAG P + +GL +PG GP PG G P Sbjct: 1204 GADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEP 1263 Query: 343 GA-------GVPGV-------GVPG----AGIPVVPGA-GIPG----AAVPGVVSPEAAA 379 G G PG G PG +G +PG G+PG G P+ Sbjct: 1264 GLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPR 1323 Query: 380 KAAAKAAKYGARPGVGVGGIPTYGVGAG-----GFPGF--GVGVGGIPGVAGVPGVGGVP 432 K G+ G G P G G PGF G G PG GVPG GVP Sbjct: 1324 GPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVP 1383 Query: 433 GVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAP 492 G G PG K G G P GL+ G+ PG Sbjct: 1384 GKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPG--IPGHKGHTGLMGPQGL-PGENGPV 1440 Query: 493 GVGVAPGVGLAPGV-GVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGL 551 G PG PG+ G +P + + + +G A A++ A ++++ G Sbjct: 1441 GPPGPPGQPGFPGLRGESPSMETLRRL-IQEELGKQLETRLAYLLAQM-PPAYMKSSQG- 1497 Query: 552 GAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGL 611 G PG G+PG G PG G+ G + P + AK PGV G Sbjct: 1498 RPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEG-PSGPIGPKGERGAKGDPGAPGV-GLR 1555 Query: 612 GALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGI 671 G +G GIPG G A+ GL G G G G G PG+ G G Sbjct: 1556 GEMGPPGIPGQPGEPG-------------YAKDGLPGIPGPQG-ETGPAGHPGLPGPPGP 1601 Query: 672 PPAAAAKAAKY--GVAARPG 689 P Y +AARPG Sbjct: 1602 PGQCDPSQCAYFASLAARPG 1621 Score = 113 bits (283), Expect = 5e-25 Identities = 191/640 (29%), Positives = 233/640 (36%), Gaps = 98/640 (15%) Query: 110 AGLGGVPGVGG-LGVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGV 168 AG G GV G +G+ GA+ P G K K G G+ P G + Sbjct: 480 AGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEK----GDVGIGPFGQGEKGEKGSL 535 Query: 169 GVLPGVPTGAGVKPKA--PGVGGAFAGIPGVGPFGGPQ--PGVPLGYP--IKAPKLPGGY 222 G LPG P G K PG G G+PG GPQ PG+P G P + AP L G Sbjct: 536 G-LPGPPGRDGSKGMRGEPGELGE-PGLPGEVGMRGPQGPPGLP-GPPGRVGAPGLQGER 592 Query: 223 GLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGV 282 G T G+ G G+ G GK G TG P + A G G V Sbjct: 593 GEKGTRGEK----GERGLDGFPGKPG-DTGQQGRPGPSGVA----------GPQGEKGDV 637 Query: 283 GGAGVPGVPGAIPGIGGIAG-VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGV 341 G AG PGVPG++ G+ G G P A GA + P G PG+ G+ Sbjct: 638 GPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPP---GARGPIGPEGRDGPPGLQGL 694 Query: 342 PG-------AGVPGV----GVPG-AGIPVVPG----AGIPG-AAVPGVVSPEAAAKAAAK 384 G G+PG+ G PG G+P PG G+PG PG P K Sbjct: 695 RGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGK 754 Query: 385 AAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISP 444 G G G P G G PG G+ G G G+ G G G G+PG P Sbjct: 755 DGPNGPPGPPGTKGEPGER-GEDGLPG-KPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFP 812 Query: 445 EAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPG-VGVAPGVGVAPGVGLA 503 + + K +G P + A PG+ PG + PG Sbjct: 813 GVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGL---PGTTSLFTPHPRMPGEQGP 869 Query: 504 PGVGVAPGVGVAPGVGVAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLG-AGIPGLGVG 561 G PG+ PG+ PG +GP G AK Q A G AG PG Sbjct: 870 KGEKGDPGLPGEPGLQGRPGELGPQG------PTGPPGAKGQEGAHGAPGAAGNPGAPGH 923 Query: 562 VGVPGLGVGAGVPGLGVGAGVPGFGAVPG--ALAAAKAAKYGAAVPGVLGGLGALGGVGI 619 VG PG +G PG G PG PG K A PG +G G G G+ Sbjct: 924 VGAPG---PSGPPG---SVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGL 977 Query: 620 PG----------GVVGA----GPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL----- 660 PG G+ G+ GP AA + L G G G G+ Sbjct: 978 PGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPG 1037 Query: 661 --GVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPG 698 G PG+G G PP + G PG P FPG Sbjct: 1038 SRGDPGIGVAG--PPGPSGPPGDKG---SPGSRGLPGFPG 1072 >gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens] Length = 744 Score = 145 bits (366), Expect = 1e-34 Identities = 166/512 (32%), Positives = 197/512 (38%), Gaps = 78/512 (15%) Query: 136 QPGAGVKPGK--VPGVGLPGVY----PGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGG 189 +PG PG +PG G+PG+ P G PG PG+ +PG P G+ PG G Sbjct: 125 EPGPRGPPGPPGLPGHGIPGIKGKPGPQGY-PGVGKPGMPGMPGKPGAMGM----PGAKG 179 Query: 190 AFAGIPGVGPFGGPQPGVPLGYPIKAPKL--PGGYGLPYTTGKLPYG-YGPGGVAGAAGK 246 +GP G P P P G P P + PGG GLP G P G GP G+ G G Sbjct: 180 EIGQKGEIGPMGIPGPQGPPG-PHGLPGIGKPGGPGLPGQPG--PKGDRGPKGLPGPQGL 236 Query: 247 AGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTP 306 G G G A PGV G PG+ G PG G+ GVG P Sbjct: 237 RGPKGDKGFGMPGA-------------------PGVKGP--PGMHGP-PGPVGLPGVGKP 274 Query: 307 AAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGA-GIPVVPG--AG 363 K GA P GP PGV G P G+PG+G PG GIP PG G Sbjct: 275 GVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPP--GIPGIGKPGQDGIPGQPGFPGG 332 Query: 364 IPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGI--PTYGVGAGGFPGFGVGVGGIPG 421 +PG+ P PG+G G P G GG PG +G G G Sbjct: 333 KGEQGLPGLPGPPGL-------------PGIGKPGFPGPKGDRGMGGVPG-ALGPRGEKG 378 Query: 422 VAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPG 481 G PG+GG PG G+PG+ P A G G K PG Sbjct: 379 PIGAPGIGGPPGEPGLPGIP-GPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGE-----PG 432 Query: 482 VGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAA 541 + PG G PG+ PG G GV PG+ PG K + Sbjct: 433 LQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGV-PG--LLGPKGEPGIPG 489 Query: 542 KAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYG 601 L+ G+ GI G +G PG+ G PGL G PG G PG A +G Sbjct: 490 DQGLQGPPGI-PGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGK-PGV-----AGLHG 542 Query: 602 AAVPGVLGGLGALGGVGIPGGVVGAGPAAAAA 633 PG G LG G G+PG GP A Sbjct: 543 P--PGKPGALGPQGQPGLPGPPGPPGPPGPPA 572 Score = 132 bits (332), Expect = 1e-30 Identities = 170/493 (34%), Positives = 202/493 (40%), Gaps = 81/493 (16%) Query: 7 AAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGG----------GAL 56 A P+ G + L S+ P G PG P G PG PG G+ + G G Sbjct: 103 AVPKKGKEIPLASLRGEQGPRGEPG--PRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKP 160 Query: 57 GPGGKPLKPVPGGLAGAGLGAGL-GAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGV 115 G G P KP G+ GA G G + PG P G K G GL G Sbjct: 161 GMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPG--GPGLPGQ 218 Query: 116 PGV-GGLGVSAAPSVPGAVVPQPGAGVKPGKVPGV-GLPGVY--PGGV-LPGARFPGVGV 170 PG G G P G P+ G PGV G PG++ PG V LPG PGV Sbjct: 219 PGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTG 278 Query: 171 LPGVPTGAGVKPKAPGVGGAFA--GIPGVGPFGGPQPGVP-LGYPIKAPKLPGGYGLPYT 227 PG P G KP APG G G+PGV GP PG+P +G P + +PG G P Sbjct: 279 FPG-PQGPLGKPGAPGEPGPQGPIGVPGVQ---GP-PGIPGIGKPGQ-DGIPGQPGFPGG 332 Query: 228 TGK--LPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVL--PGVG 283 G+ LP GP G+ G GK G+P GP+ A G G + PG+G Sbjct: 333 KGEQGLPGLPGPPGLPGI-GKPGFP-----GPKGDRGMGGVPGALGPRGEKGPIGAPGIG 386 Query: 284 GA-GVPGVPGAIPGIGGIAG-VGTPAAAAAAAAAAKAAKYGAAA--GL--VPGGPGF--- 334 G G PG+PG IPG G G +G P G GL PG PGF Sbjct: 387 GPPGEPGLPG-IPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGE 445 Query: 335 --GPGVVGVPGA----------GVPGV-GVPGA----GIPVVPG-------AGIPGAAVP 370 PG+ G+PG GVPG+ GVPG G P +PG GIPG P Sbjct: 446 VGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGP 505 Query: 371 -GVVSPEAAAKAAAKAAKYGAR--PGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPG 427 G + P + G PG+G G+ G G PG G G G G+PG Sbjct: 506 SGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGV----AGLHGPPG-KPGALGPQGQPGLPG 560 Query: 428 VGGVPGVGGVPGV 440 G PG G P V Sbjct: 561 PPGPPGPPGPPAV 573 Score = 129 bits (325), Expect = 7e-30 Identities = 179/574 (31%), Positives = 211/574 (36%), Gaps = 134/574 (23%) Query: 123 VSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKP 182 + AP + VP+ G ++P L G PG R P P Sbjct: 93 IQPAPRMGKEAVPKKGK-----EIPLASLRGEQGPRGEPGPRGP---------------P 132 Query: 183 KAPGVGGAFAGIPGVGPFGGPQPGVPLGYP-IKAPKLPGGYGLPYTTGKLPYGYGPGGVA 241 PG+ G GIPG+ GPQ GYP + P +PG G P G +P G G Sbjct: 133 GPPGLPGH--GIPGIKGKPGPQ-----GYPGVGKPGMPGMPGKPGAMG-MPGAKGEIGQK 184 Query: 242 GAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIA 301 G G G P GPQ G LPG+G G PG+PG PG G Sbjct: 185 GEIGPMGIP-----GPQ-------------GPPGPHGLPGIGKPGGPGLPGQ-PGPKGDR 225 Query: 302 GV-GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFG--PGVVGVPGAGVPGV-GVPGAGIP 357 G G P A V G PG PG VG+PG G PGV G PG P Sbjct: 226 GPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGP 285 Query: 358 VVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGV-GV 416 + G PGA PG P+ +GV G+ G G PG G G Sbjct: 286 L----GKPGA--PGEPGPQGP---------------IGVPGVQ----GPPGIPGIGKPGQ 320 Query: 417 GGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQF 476 GIPG G PG G G+ G+PG P G+G P K Sbjct: 321 DGIPGQPGFPGGKGEQGLPGLPGPPGLP-------------GIGKPGFPGPKGDRG---M 364 Query: 477 GLVPGV----GVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI-GPGGVAA 531 G VPG G +G APG+G PG PG+ PG PG PG G GG+ Sbjct: 365 GGVPGALGPRGEKGPIG-APGIGGPPGEPGLPGI---PGPMGPPGAIGFPGPKGEGGIVG 420 Query: 532 AAKSAAKVAAKAQLRAAAGLGA--GIPGLGVGVGVPGLGVGAGVPGLGVGA-------GV 582 + GL G PG VG PG+ G+PG +G GV Sbjct: 421 PQGPPGP-------KGEPGLQGFPGKPGFLGEVGPPGM---RGLPG-PIGPKGEAGQKGV 469 Query: 583 PGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAA 642 PG VPG L PG+ G G G GIPG +GP + Sbjct: 470 PGLPGVPGLLGPK-------GEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPG 522 Query: 643 QFGLVGAAGLGGLGVGGL----GVPGVGGLGGIP 672 G G G+G GV GL G PG G G P Sbjct: 523 LPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQP 556 Score = 122 bits (306), Expect = 1e-27 Identities = 167/562 (29%), Positives = 206/562 (36%), Gaps = 104/562 (18%) Query: 179 GVKPKAPGVGGAFAG-IPGVGPFGGPQPGVPLGYPIKA-----PKLPGGYGLPYTTGKLP 232 G+KP P + IP P G P +PL A P L G P+ LP Sbjct: 32 GIKPLPPQIPPQMPPQIPQYQPLGQQVPHMPLAKDGLAMGKEMPHLQYGKEYPH----LP 87 Query: 233 YGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG 292 A GK P P A+ + G PG+ G G+PG+ G Sbjct: 88 QYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKG 147 Query: 293 AIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA----GVPG 348 PG G GVG P +PG PG PG +G+PGA G G Sbjct: 148 K-PGPQGYPGVGKPG--------------------MPGMPG-KPGAMGMPGAKGEIGQKG 185 Query: 349 ----VGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGV 404 +G+PG P P G+PG PG P + K G R G+ G P Sbjct: 186 EIGPMGIPGPQGPPGPH-GLPGIGKPG--GPGLPGQPGPK----GDRGPKGLPG-PQGLR 237 Query: 405 GAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAA 464 G G GFG+ G PGV G PG+ G PG G+PGVG P + G P Sbjct: 238 GPKGDKGFGMP--GAPGVKGPPGMHGPPGPVGLPGVG-KPGVTGFPGPQGPLGKPGAPGE 294 Query: 465 AAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI 524 + PG+ PG+G PG PG PG G+ PG PGI Sbjct: 295 PGPQGPIGVPGVQGPPGI---PGIG-KPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGI 350 Query: 525 GPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPG-LGV-----GVGVPGLGVGAGVPGLGV 578 G G + G+G G+PG LG +G PG+G G PGL Sbjct: 351 GKPGFPGP-------------KGDRGMG-GVPGALGPRGEKGPIGAPGIGGPPGEPGL-- 394 Query: 579 GAGVPGFGAVPGALAAAKAAKYGAAV--------------------PGVLGGLGALGGVG 618 G+PG PGA+ G V PG LG +G G G Sbjct: 395 -PGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRG 453 Query: 619 IPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL-GVGGL-GVPGVGGLGGIPPAAA 676 +PG + GP A GL+G G G+ G GL G PG+ G+GG P Sbjct: 454 LPGPI---GPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGG-PSGPI 509 Query: 677 AKAAKYGVAARPGFGLSPIFPG 698 G PG P FPG Sbjct: 510 GPPGIPGPKGEPGLPGPPGFPG 531 Score = 110 bits (276), Expect = 3e-24 Identities = 139/415 (33%), Positives = 164/415 (39%), Gaps = 76/415 (18%) Query: 23 PSRPG--GVPGAIPGGVPGGVFYPGAGLGALGG-----GALGPGGKPLKPVPGGLAGAGL 75 P PG G PG G PG V PG G + G G LG G P +P P G G Sbjct: 248 PGAPGVKGPPGM--HGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPG 305 Query: 76 GAGLGAFPAVTFPGAL-VPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVV 134 G P + PG +PG + K GL G+PG GL P PG Sbjct: 306 VQGPPGIPGIGKPGQDGIPG-----QPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPG--- 357 Query: 135 PQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGI 194 P+ G+ G VPG P G + GA PG+G PG P G+ P G GA G Sbjct: 358 PKGDRGM--GGVPGALGPRGEKGPI--GA--PGIGGPPGEPGLPGI-PGPMGPPGAI-GF 409 Query: 195 PG-------VGPFGGPQP-GVP--LGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAA 244 PG VGP G P P G P G+P K P G G P G LP GP G AG Sbjct: 410 PGPKGEGGIVGPQGPPGPKGEPGLQGFPGK-PGFLGEVGPPGMRG-LPGPIGPKGEAGQK 467 Query: 245 GKAGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG-----AIPGIG 298 G G P G+ GP+ + G G+ G G PG+PG +PG Sbjct: 468 GVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPP 527 Query: 299 GIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPG--GPGFGPGVVGVPGAGVPGVGVPGAGI 356 G G+G P A K PG GP PG+ G PG PG P A + Sbjct: 528 GFPGIGKPGVAGLHGPPGK-----------PGALGPQGQPGLPGPPGP--PGPPGPPAVM 574 Query: 357 PVVP---GAGIP--GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGA 406 P P G +P G + GV P A YGA+ G G P Y + A Sbjct: 575 PPTPPPQGEYLPDMGLGIDGVKPPHA----------YGAKKGKNGG--PAYEMPA 617 >gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens] Length = 744 Score = 145 bits (366), Expect = 1e-34 Identities = 166/512 (32%), Positives = 197/512 (38%), Gaps = 78/512 (15%) Query: 136 QPGAGVKPGK--VPGVGLPGVY----PGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGG 189 +PG PG +PG G+PG+ P G PG PG+ +PG P G+ PG G Sbjct: 125 EPGPRGPPGPPGLPGHGIPGIKGKPGPQGY-PGVGKPGMPGMPGKPGAMGM----PGAKG 179 Query: 190 AFAGIPGVGPFGGPQPGVPLGYPIKAPKL--PGGYGLPYTTGKLPYG-YGPGGVAGAAGK 246 +GP G P P P G P P + PGG GLP G P G GP G+ G G Sbjct: 180 EIGQKGEIGPMGIPGPQGPPG-PHGLPGIGKPGGPGLPGQPG--PKGDRGPKGLPGPQGL 236 Query: 247 AGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTP 306 G G G A PGV G PG+ G PG G+ GVG P Sbjct: 237 RGPKGDKGFGMPGA-------------------PGVKGP--PGMHGP-PGPVGLPGVGKP 274 Query: 307 AAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGA-GIPVVPG--AG 363 K GA P GP PGV G P G+PG+G PG GIP PG G Sbjct: 275 GVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPP--GIPGIGKPGQDGIPGQPGFPGG 332 Query: 364 IPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGI--PTYGVGAGGFPGFGVGVGGIPG 421 +PG+ P PG+G G P G GG PG +G G G Sbjct: 333 KGEQGLPGLPGPPGL-------------PGIGKPGFPGPKGDRGMGGVPG-ALGPRGEKG 378 Query: 422 VAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPG 481 G PG+GG PG G+PG+ P A G G K PG Sbjct: 379 PIGAPGIGGPPGEPGLPGIP-GPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGE-----PG 432 Query: 482 VGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAA 541 + PG G PG+ PG G GV PG+ PG K + Sbjct: 433 LQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGV-PG--LLGPKGEPGIPG 489 Query: 542 KAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYG 601 L+ G+ GI G +G PG+ G PGL G PG G PG A +G Sbjct: 490 DQGLQGPPGI-PGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGK-PGV-----AGLHG 542 Query: 602 AAVPGVLGGLGALGGVGIPGGVVGAGPAAAAA 633 PG G LG G G+PG GP A Sbjct: 543 P--PGKPGALGPQGQPGLPGPPGPPGPPGPPA 572 Score = 132 bits (332), Expect = 1e-30 Identities = 170/493 (34%), Positives = 202/493 (40%), Gaps = 81/493 (16%) Query: 7 AAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGG----------GAL 56 A P+ G + L S+ P G PG P G PG PG G+ + G G Sbjct: 103 AVPKKGKEIPLASLRGEQGPRGEPG--PRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKP 160 Query: 57 GPGGKPLKPVPGGLAGAGLGAGL-GAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGV 115 G G P KP G+ GA G G + PG P G K G GL G Sbjct: 161 GMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPG--GPGLPGQ 218 Query: 116 PGV-GGLGVSAAPSVPGAVVPQPGAGVKPGKVPGV-GLPGVY--PGGV-LPGARFPGVGV 170 PG G G P G P+ G PGV G PG++ PG V LPG PGV Sbjct: 219 PGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTG 278 Query: 171 LPGVPTGAGVKPKAPGVGGAFA--GIPGVGPFGGPQPGVP-LGYPIKAPKLPGGYGLPYT 227 PG P G KP APG G G+PGV GP PG+P +G P + +PG G P Sbjct: 279 FPG-PQGPLGKPGAPGEPGPQGPIGVPGVQ---GP-PGIPGIGKPGQ-DGIPGQPGFPGG 332 Query: 228 TGK--LPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVL--PGVG 283 G+ LP GP G+ G GK G+P GP+ A G G + PG+G Sbjct: 333 KGEQGLPGLPGPPGLPGI-GKPGFP-----GPKGDRGMGGVPGALGPRGEKGPIGAPGIG 386 Query: 284 GA-GVPGVPGAIPGIGGIAG-VGTPAAAAAAAAAAKAAKYGAAA--GL--VPGGPGF--- 334 G G PG+PG IPG G G +G P G GL PG PGF Sbjct: 387 GPPGEPGLPG-IPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGE 445 Query: 335 --GPGVVGVPGA----------GVPGV-GVPGA----GIPVVPG-------AGIPGAAVP 370 PG+ G+PG GVPG+ GVPG G P +PG GIPG P Sbjct: 446 VGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGP 505 Query: 371 -GVVSPEAAAKAAAKAAKYGAR--PGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPG 427 G + P + G PG+G G+ G G PG G G G G+PG Sbjct: 506 SGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGV----AGLHGPPG-KPGALGPQGQPGLPG 560 Query: 428 VGGVPGVGGVPGV 440 G PG G P V Sbjct: 561 PPGPPGPPGPPAV 573 Score = 129 bits (325), Expect = 7e-30 Identities = 179/574 (31%), Positives = 211/574 (36%), Gaps = 134/574 (23%) Query: 123 VSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKP 182 + AP + VP+ G ++P L G PG R P P Sbjct: 93 IQPAPRMGKEAVPKKGK-----EIPLASLRGEQGPRGEPGPRGP---------------P 132 Query: 183 KAPGVGGAFAGIPGVGPFGGPQPGVPLGYP-IKAPKLPGGYGLPYTTGKLPYGYGPGGVA 241 PG+ G GIPG+ GPQ GYP + P +PG G P G +P G G Sbjct: 133 GPPGLPGH--GIPGIKGKPGPQ-----GYPGVGKPGMPGMPGKPGAMG-MPGAKGEIGQK 184 Query: 242 GAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIA 301 G G G P GPQ G LPG+G G PG+PG PG G Sbjct: 185 GEIGPMGIP-----GPQ-------------GPPGPHGLPGIGKPGGPGLPGQ-PGPKGDR 225 Query: 302 GV-GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFG--PGVVGVPGAGVPGV-GVPGAGIP 357 G G P A V G PG PG VG+PG G PGV G PG P Sbjct: 226 GPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGP 285 Query: 358 VVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGV-GV 416 + G PGA PG P+ +GV G+ G G PG G G Sbjct: 286 L----GKPGA--PGEPGPQGP---------------IGVPGVQ----GPPGIPGIGKPGQ 320 Query: 417 GGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQF 476 GIPG G PG G G+ G+PG P G+G P K Sbjct: 321 DGIPGQPGFPGGKGEQGLPGLPGPPGLP-------------GIGKPGFPGPKGDRG---M 364 Query: 477 GLVPGV----GVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI-GPGGVAA 531 G VPG G +G APG+G PG PG+ PG PG PG G GG+ Sbjct: 365 GGVPGALGPRGEKGPIG-APGIGGPPGEPGLPGI---PGPMGPPGAIGFPGPKGEGGIVG 420 Query: 532 AAKSAAKVAAKAQLRAAAGLGA--GIPGLGVGVGVPGLGVGAGVPGLGVGA-------GV 582 + GL G PG VG PG+ G+PG +G GV Sbjct: 421 PQGPPGP-------KGEPGLQGFPGKPGFLGEVGPPGM---RGLPG-PIGPKGEAGQKGV 469 Query: 583 PGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAA 642 PG VPG L PG+ G G G GIPG +GP + Sbjct: 470 PGLPGVPGLLGPK-------GEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPG 522 Query: 643 QFGLVGAAGLGGLGVGGL----GVPGVGGLGGIP 672 G G G+G GV GL G PG G G P Sbjct: 523 LPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQP 556 Score = 122 bits (306), Expect = 1e-27 Identities = 167/562 (29%), Positives = 206/562 (36%), Gaps = 104/562 (18%) Query: 179 GVKPKAPGVGGAFAG-IPGVGPFGGPQPGVPLGYPIKA-----PKLPGGYGLPYTTGKLP 232 G+KP P + IP P G P +PL A P L G P+ LP Sbjct: 32 GIKPLPPQIPPQMPPQIPQYQPLGQQVPHMPLAKDGLAMGKEMPHLQYGKEYPH----LP 87 Query: 233 YGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG 292 A GK P P A+ + G PG+ G G+PG+ G Sbjct: 88 QYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKG 147 Query: 293 AIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA----GVPG 348 PG G GVG P +PG PG PG +G+PGA G G Sbjct: 148 K-PGPQGYPGVGKPG--------------------MPGMPG-KPGAMGMPGAKGEIGQKG 185 Query: 349 ----VGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGV 404 +G+PG P P G+PG PG P + K G R G+ G P Sbjct: 186 EIGPMGIPGPQGPPGPH-GLPGIGKPG--GPGLPGQPGPK----GDRGPKGLPG-PQGLR 237 Query: 405 GAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAA 464 G G GFG+ G PGV G PG+ G PG G+PGVG P + G P Sbjct: 238 GPKGDKGFGMP--GAPGVKGPPGMHGPPGPVGLPGVG-KPGVTGFPGPQGPLGKPGAPGE 294 Query: 465 AAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI 524 + PG+ PG+G PG PG PG G+ PG PGI Sbjct: 295 PGPQGPIGVPGVQGPPGI---PGIG-KPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGI 350 Query: 525 GPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPG-LGV-----GVGVPGLGVGAGVPGLGV 578 G G + G+G G+PG LG +G PG+G G PGL Sbjct: 351 GKPGFPGP-------------KGDRGMG-GVPGALGPRGEKGPIGAPGIGGPPGEPGL-- 394 Query: 579 GAGVPGFGAVPGALAAAKAAKYGAAV--------------------PGVLGGLGALGGVG 618 G+PG PGA+ G V PG LG +G G G Sbjct: 395 -PGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRG 453 Query: 619 IPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL-GVGGL-GVPGVGGLGGIPPAAA 676 +PG + GP A GL+G G G+ G GL G PG+ G+GG P Sbjct: 454 LPGPI---GPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGG-PSGPI 509 Query: 677 AKAAKYGVAARPGFGLSPIFPG 698 G PG P FPG Sbjct: 510 GPPGIPGPKGEPGLPGPPGFPG 531 Score = 110 bits (276), Expect = 3e-24 Identities = 139/415 (33%), Positives = 164/415 (39%), Gaps = 76/415 (18%) Query: 23 PSRPG--GVPGAIPGGVPGGVFYPGAGLGALGG-----GALGPGGKPLKPVPGGLAGAGL 75 P PG G PG G PG V PG G + G G LG G P +P P G G Sbjct: 248 PGAPGVKGPPGM--HGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPG 305 Query: 76 GAGLGAFPAVTFPGAL-VPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVV 134 G P + PG +PG + K GL G+PG GL P PG Sbjct: 306 VQGPPGIPGIGKPGQDGIPG-----QPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPG--- 357 Query: 135 PQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGI 194 P+ G+ G VPG P G + GA PG+G PG P G+ P G GA G Sbjct: 358 PKGDRGM--GGVPGALGPRGEKGPI--GA--PGIGGPPGEPGLPGI-PGPMGPPGAI-GF 409 Query: 195 PG-------VGPFGGPQP-GVP--LGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAA 244 PG VGP G P P G P G+P K P G G P G LP GP G AG Sbjct: 410 PGPKGEGGIVGPQGPPGPKGEPGLQGFPGK-PGFLGEVGPPGMRG-LPGPIGPKGEAGQK 467 Query: 245 GKAGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG-----AIPGIG 298 G G P G+ GP+ + G G+ G G PG+PG +PG Sbjct: 468 GVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPP 527 Query: 299 GIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPG--GPGFGPGVVGVPGAGVPGVGVPGAGI 356 G G+G P A K PG GP PG+ G PG PG P A + Sbjct: 528 GFPGIGKPGVAGLHGPPGK-----------PGALGPQGQPGLPGPPGP--PGPPGPPAVM 574 Query: 357 PVVP---GAGIP--GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGA 406 P P G +P G + GV P A YGA+ G G P Y + A Sbjct: 575 PPTPPPQGEYLPDMGLGIDGVKPPHA----------YGAKKGKNGG--PAYEMPA 617 >gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] Length = 2944 Score = 144 bits (362), Expect = 4e-34 Identities = 215/705 (30%), Positives = 259/705 (36%), Gaps = 120/705 (17%) Query: 22 HPSRPGGVPGAIPGGVPGGVFYPGAGLGALGG-GALGPGGKPLKPVPGGLAGAGLGAGLG 80 +P PG A P G PG + P G +GG G GP G P P G G +GL Sbjct: 2151 NPGLPGERGMAGPEGKPG-LQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGP---SGLK 2206 Query: 81 AFPAVTFPGALVPG-GVADAAAAYKAAKAGAGLGGVPGVGGL-GVSAAPSVPGAV--VPQ 136 P T P PG G+ A GL G PG GL G +P +PG V + Sbjct: 2207 GEPGETGP----PGRGLTGPTGA-------VGLPGPPGPSGLVGPQGSPGLPGQVGETGK 2255 Query: 137 PGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGG-AFAGIP 195 PGA PG+ G G +PG+ PG LPG P G +P G G A G+P Sbjct: 2256 PGA---PGRDGASGKDGDRGSPGVPGS--PG---LPG-PVGPKGEPGPTGAPGQAVVGLP 2306 Query: 196 GVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV 255 G G PG G + P G GLP GP G G AG+AG P G Sbjct: 2307 GAKGEKGA-PGGLAGDLVGEPGAKGDRGLP----------GPRGEKGEAGRAGEPGDPGE 2355 Query: 256 GPQAAAAAAAKAAAKFGAGAAGVL-----PGV-GGAGVPGVPGAIPGIGGIAG------- 302 Q A G G G PGV G G+PG+PGA PG+ G G Sbjct: 2356 DGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGA-PGVVGFPGQTGPRGE 2414 Query: 303 VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-------GVPGVGVPGA- 354 +G P + A + G L P GP PG VG PGA G PGVG+PG Sbjct: 2415 MGQPGPSGERGLAGPPGREGIPGPLGPPGP---PGSVGPPGASGLKGDKGDPGVGLPGPR 2471 Query: 355 ---GIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPG 411 G P + G PG P + G + VG G+ G G Sbjct: 2472 GERGEPGIRGED----GRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLK-------GDKG 2520 Query: 412 FGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAA 471 + G PG G G G G G+ G K + G P +K Sbjct: 2521 DSAVILGPPGPRGAKGDMGERGPRGLDG------------DKGPRGDNGDPGDKGSKGEP 2568 Query: 472 KAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGV-GVAPGVGVAPGIGPGGVA 530 +PG+ G PG PG +PG PG+ G VG +GP G+ Sbjct: 2569 GDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGF---MGPRGLK 2625 Query: 531 AAAKSAAKVAAKAQLRAAAGLGA--GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAV 588 + ++ A GL G G G PGL AG G GVPG Sbjct: 2626 G----------ERGVKGACGLDGEKGDKGEAGPPGRPGL---AGHKGEMGEPGVPGQSGA 2672 Query: 589 PG--ALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGL 646 PG L K + PG G G G G PG GP+ +A G Sbjct: 2673 PGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGP 2732 Query: 647 VGAAGLGGLGVGGLGVPG--VGGLGGIPPAAAAKAAKYGVAARPG 689 G GL G G G PG V G G+P A + G RPG Sbjct: 2733 RGPEGLQG-QKGERGPPGERVVGAPGVPGAPGER----GEQGRPG 2772 Score = 140 bits (353), Expect = 4e-33 Identities = 216/727 (29%), Positives = 265/727 (36%), Gaps = 128/727 (17%) Query: 26 PGGVPG--AIPG--GVPGGVFYPGAGLGALGG-GALGPGGKPLKPVPGGLAGAGLGAGLG 80 P G PG + G G PG PG LG G G G G+P KP GL G G G Sbjct: 1995 PIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEA 2054 Query: 81 AFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVVPQPGAG 140 P K + G G PG+ G P P V +PG G Sbjct: 2055 GRPGER------------GERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPG 2102 Query: 141 VKPGKVPGVGLPGVYPGGVLPGARFP-GVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGP 199 + + P GL G G + P G +PG+ G +P G G G+PG Sbjct: 2103 LSGEQGPP-GLKGAKGEPGSNGDQGPKGDRGVPGIKGDRG-EPGPRGQDGN-PGLPGERG 2159 Query: 200 FGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQA 259 GP+ L P P GG+G P GP G G AG AG PQ Sbjct: 2160 MAGPEGKPGLQGPRGPPGPVGGHGDP----------GPPGAPGLAGPAG--------PQG 2201 Query: 260 AAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG--------AIPGIGGIAG-VGTPAAAA 310 + + + G G+ G G+PG PG PG+ G G G P A Sbjct: 2202 PSGLKGEPG-ETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPG 2260 Query: 311 AAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG----AGVPG---VGVPGA-GIPVVPG- 361 A+ K G+ VPG PG PG VG G G PG VG+PGA G PG Sbjct: 2261 RDGASGKDGDRGSPG--VPGSPGL-PGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGG 2317 Query: 362 -----AGIPGA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGF-GV 414 G PGA G+ P A +A + G G G P G GF G GV Sbjct: 2318 LAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAP----GPKGFKGDPGV 2373 Query: 415 GVGGIPGVAGVPGVG---GVPGVGGVPGV--------------GISPEAQAAAAAKAAKY 457 GV G PG G PGV G+PG+ G PGV P + A + Sbjct: 2374 GVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGRE 2433 Query: 458 GV-------GTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAP 510 G+ G P + A+ PGVG+ PG G G PG Sbjct: 2434 GIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGL-PGPRGERGEPGIRGEDGRPGQEGPR 2492 Query: 511 GVGVAPGV----GVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAG-LGA------------ 553 G+ PG G +G G+ +A + R A G +G Sbjct: 2493 GLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGP 2552 Query: 554 ----GIPGLGVGVGVPGLGVGAGVPGL-GV--GAGVPGFGAVPGALAAAKAAKYGAAVPG 606 G PG G PG AG+PGL G+ G PG +PG K G VPG Sbjct: 2553 RGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPG--DPGSPGKDG--VPG 2608 Query: 607 VLGGLGALGGVGIPGGVVG-AGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGV 665 + G G +G +G P G+ G G A + G G GL G G +G PGV Sbjct: 2609 IRGEKGDVGFMG-PRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAG-HKGEMGEPGV 2666 Query: 666 GGLGGIP 672 G G P Sbjct: 2667 PGQSGAP 2673 Score = 131 bits (330), Expect = 2e-30 Identities = 210/728 (28%), Positives = 244/728 (33%), Gaps = 133/728 (18%) Query: 26 PGGVPGAIPG--GVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFP 83 P G PG +PG G PG PG+ G G G+P P G G GL P Sbjct: 1270 PPGDPG-LPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSP 1328 Query: 84 AVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPG--VGGLGVSAAPSVPGAVVPQPGAGV 141 +PG D + + G G PG +GG G P +PG PG Sbjct: 1329 G-------LPGPRGDPGE--RGPRGPKGEPGAPGQVIGGEG----PGLPGR-KGDPGPSG 1374 Query: 142 KPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVK-PKAPGVGGAFAGIPGV-GP 199 PG +G PG LPG + G G + P PG GG G PG+ G Sbjct: 1375 PPGPRGPLGDPGPRGPPGLPGT------AMKGDKGDRGERGPPGPGEGGIAPGEPGLPGL 1428 Query: 200 FGGPQPGVPLGYPIK----------APKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGY 249 G P P P+G P K AP LPG G P G GP G G G G+ Sbjct: 1429 PGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGP----RGPPGAIGPKGDRGF 1484 Query: 250 PTGTG-------------VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG---- 292 P G G + A + AK G G G G PG PG Sbjct: 1485 PGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAV 1544 Query: 293 AIPGIGGIAG-VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPG-------FGP----GVVG 340 P + G G G A A + G ++PG PG GP G G Sbjct: 1545 VGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAG 1604 Query: 341 VPG-AGVPG----VGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVG 395 PG +G PG G PG PV P G P KA + G R G Sbjct: 1605 PPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPG 1664 Query: 396 VGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAA 455 V G P G G PG G G PG +G G G PG G PG + A + Sbjct: 1665 VRG-PVGEKGDQGDPGED-GRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPG 1722 Query: 456 KYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGV-GVA----- 509 G P PG+ APG G PG PGV G A Sbjct: 1723 DRGQEGPRGPKGD-----------PGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGD 1771 Query: 510 ---PGVGVAPGVGVAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVP 565 PG+ G+ PG GP G AA A G+PGL G+P Sbjct: 1772 RGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRD-----------GLPGLRGEQGLP 1820 Query: 566 GLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVG 625 G G+PG G PG G PG G G G G G Sbjct: 1821 GPSGPPGLPGKPGEDGKPGLNGKNGE----------PGDPGEDGRKGEKGDSGASGREGR 1870 Query: 626 AGPAAAAAAAKAAAKAAQFGLVGAAGLGGL----GVGGLGVPGVGGLGGIPPAAAAKAAK 681 GP A G++G G GL G G G PGV G G P + Sbjct: 1871 DGPKGERGAP---------GILGPQGPPGLPGPVGPPGQGFPGVPG-GTGPKGDRGETGS 1920 Query: 682 YGVAARPG 689 G PG Sbjct: 1921 KGEQGLPG 1928 Score = 124 bits (310), Expect = 4e-28 Identities = 216/767 (28%), Positives = 270/767 (35%), Gaps = 128/767 (16%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAF 82 P+ P G G P G+ PG G GP G + P G +G G Sbjct: 1561 PAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGR 1620 Query: 83 PAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG-LGVSAAPSVPGAVVPQPGAGV 141 P PG + P G D K + G G+PG G G+ AP V G V + G Sbjct: 1621 PGP--PGPVGPRG-RDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQG- 1676 Query: 142 KPGKVPGVGLPGVYPGGVLPGARFPGVGVLPG--VPTGAGVKPKA--------------- 184 PG+ G PG G PG PG V TG G + K Sbjct: 1677 DPGEDGRNGSPG--SSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKG 1734 Query: 185 -PGVGGAFAGIPGVGPFGGPQPGVPLGYP-IKAPK-------LPGGYGLPYTTGKLPYGY 235 PG+ GA G G+ F GP PG P G P ++ P PG G GK P Sbjct: 1735 DPGLPGA-PGERGIEGFRGP-PG-PQGDPGVRGPAGEKGDRGPPGLDGRSGLDGK-PGAA 1790 Query: 236 GPGGVAGAAGKAGYPTGTGV----GPQAAAAAAAKAAAKFGAGAAGVLPGVGGA-GVPGV 290 GP G GAAGKAG P G+ G Q + G G PG+ G G PG Sbjct: 1791 GPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGK-PGLNGKNGEPGD 1849 Query: 291 PGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGV- 349 PG G G A+ + GA L P GP PG VG PG G PGV Sbjct: 1850 PGED---GRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVP 1906 Query: 350 ------------------GVPG-AGIPVVPG-----------AGIPGAAVPGVVS----- 374 G+PG G+ PG AGI +A+ +V Sbjct: 1907 GGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDES 1966 Query: 375 -------PEAAAKAAAKAAKYGARPGVGVGGIP--------TYGVGAGGFPGFGVGVGGI 419 PE + + G G G P G G PG +G G Sbjct: 1967 SGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGP 2026 Query: 420 PGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLV 479 PG +G+ G G PG+ G+PG +A +A + G + + Sbjct: 2027 PGPSGLAGEPGKPGIPGLPG-------RAGGVGEAGRPGERGERGEKGERGEQGRDG--P 2077 Query: 480 PGVGVAPGVGVAPGVGVA---PGVGLAPGVGVAPGVGVAPGVGVAPG----IGPGGVAAA 532 PG+ PG PG V+ PG GL+ G PG+ A G + G G GV Sbjct: 2078 PGLPGTPGPPGPPGPKVSVDEPGPGLSGEQG-PPGLKGAKGEPGSNGDQGPKGDRGVPGI 2136 Query: 533 AKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGAL 592 + + Q GL G G+ G PGL G PG G G PG PG Sbjct: 2137 KGDRGEPGPRGQ-DGNPGL-PGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLA 2194 Query: 593 AAA----------KAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAA 642 A + + G G+ G GA+G G PG GP + + Sbjct: 2195 GPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETG 2254 Query: 643 QFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPG 689 + G G G G G G PGV G G+P K + G PG Sbjct: 2255 KPGAPGRDGASGKD-GDRGSPGVPGSPGLPGPVGPK-GEPGPTGAPG 2299 Score = 121 bits (304), Expect = 2e-27 Identities = 199/697 (28%), Positives = 245/697 (35%), Gaps = 88/697 (12%) Query: 23 PSRPG--GVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKP-VPGGLAGAGLGAGL 79 P PG G+PG+ PG P G P G G G G P +P PG G + Sbjct: 1420 PGEPGLPGLPGS-PG--PQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAI 1476 Query: 80 GAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVVPQPGA 139 G FPG L G + AG G+PGV G + P P + G Sbjct: 1477 GPKGDRGFPGPLGEAG----EKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGE 1532 Query: 140 GVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGA-GVKPKAPGVGGAFAGIPGVG 198 +PG+ G P V G + G + V P P GA GV+ + G G P G Sbjct: 1533 KGEPGR---PGDPAVV-GPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDP--G 1586 Query: 199 PFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTG-VGP 257 P G P P+G +A PG G P G P GP G G G+ G G GP Sbjct: 1587 PKGDPGDRGPIGLTGRAGP-PGDSGPPGEKGD-PGRPGPPGPVGPRGRDGEVGEKGDEGP 1644 Query: 258 QAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG-----AIPGIGGIAG----VGTPAA 308 KA + GA GV VG G G PG PG G G G P Sbjct: 1645 PGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGP 1704 Query: 309 AA----AAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AGVPGV-GVPG-AGIPVVPG 361 A + + G P GP PG+ G PG G+ G G PG G P V G Sbjct: 1705 PGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRG 1764 Query: 362 -AGIPG-AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGI 419 AG G PG+ A G G G P G G PG G G+ Sbjct: 1765 PAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDP----GRDGLPGLR-GEQGL 1819 Query: 420 PGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLV 479 PG +G PG+ G PG G PG+ + + + G + A+ + + Sbjct: 1820 PGPSGPPGLPGKPGEDGKPGLN-GKNGEPGDPGEDGRKGEKGDSGASGREGRDGPK---- 1874 Query: 480 PGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGG--VAAAAKSAA 537 G APG+ G PG PG G PGV PG G GP G +K Sbjct: 1875 -GERGAPGILGPQGPPGLPGPVGPPGQGF-PGV---PG-----GTGPKGDRGETGSKGEQ 1924 Query: 538 KVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKA 597 + + LR G + L G+ + V +G F VP K Sbjct: 1925 GLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSG--SFLPVPERRRGPKG 1982 Query: 598 AKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGV 657 PG G +G G G+ G GP G GL + Sbjct: 1983 DSGEQGPPGKEGPIGFPGERGLKGDRGDPGP---------------------QGPPGLAL 2021 Query: 658 GGLGVPGVGGLGGIP-----PAAAAKAAKYGVAARPG 689 G G PG GL G P P +A G A RPG Sbjct: 2022 GERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPG 2058 Score = 116 bits (290), Expect = 8e-26 Identities = 190/637 (29%), Positives = 224/637 (35%), Gaps = 115/637 (18%) Query: 111 GLGGVPGVGG-LGVSAAPSVPGAVVPQ-----PGAGVKPGKVPGVGLPGVYPG--GVLPG 162 G G PG+ G G PG+ + PGA +PG G PG PG G+ Sbjct: 1269 GPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGT-PGAPGLKGS 1327 Query: 163 ARFPGVGVLPGV--PTGAGVKPKAPG--VGGAFAGIPG----VGPFGGPQPGVPLGYPIK 214 PG PG P G +P APG +GG G+PG GP G P P PLG P Sbjct: 1328 PGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDP-- 1385 Query: 215 APKLPGGYGLPYTTGKL---------PYGYGPGGVA-GAAGKAGYPTGTGVGPQAAAAAA 264 P+ P G LP T K P G G GG+A G G G P G PQ Sbjct: 1386 GPRGPPG--LPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPG--PQGPVGPP 1441 Query: 265 AKAAAKFGA--GAAGVLPG----------------VGGAGVPGVPGAIPGIGGIAGVGTP 306 K K + GA G LPG +G G G PG + G G P Sbjct: 1442 GKKGEKGDSEDGAPG-LPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPP 1500 Query: 307 AAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIPG 366 A + A + GA P GP G G PG G P V G + G Sbjct: 1501 GPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGR---------PGDPAVVGPAVAG 1551 Query: 367 -AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPG----FGV-GVGGIP 420 G V P A + G PG+ + G P G G PG G+ G G P Sbjct: 1552 PKGEKGDVGPAGPRGATGVQGERGP-PGLVLPGDP----GPKGDPGDRGPIGLTGRAGPP 1606 Query: 421 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVP 480 G +G PG G PG G PG + P + + G KA + Sbjct: 1607 GDSGPPGEKGDPGRPGPPG-PVGPRGRDGEVGEKGDEGPPGDPGLPGKAGER-------- 1657 Query: 481 GVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG-IGPGGVAAAAKSAAKV 539 G+ APGV G G G +PG G PG GP G A+ Sbjct: 1658 GLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAR- 1716 Query: 540 AAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAK 599 G PG G G G+PG G+ GF PG Sbjct: 1717 ------------EKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGP-------- 1756 Query: 600 YGAAVPGVLGGLGALGGVGIPG-----GVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGG 654 PGV G G G G PG G+ G AA + AA A G G GL G Sbjct: 1757 --QGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKA--GDPGRDGLPG 1812 Query: 655 LGVGGLGVPGVGGLGGIP--PAAAAKAAKYGVAARPG 689 L G G+PG G G+P P K G PG Sbjct: 1813 LR-GEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPG 1848 Score = 101 bits (251), Expect = 3e-21 Identities = 151/510 (29%), Positives = 175/510 (34%), Gaps = 80/510 (15%) Query: 232 PYGYGPGGVAGAAGKAGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGV 290 P G G G G G P TG GPQ +A + GA G G AG PG Sbjct: 1259 PGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGT 1318 Query: 291 PGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFG-PGVVGVPG-AGVPG 348 PGA PG+ G G+ P A G V GG G G PG G PG +G PG Sbjct: 1319 PGA-PGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPG 1377 Query: 349 ----VGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGV 404 +G PG P G+PG A+ G PG G GGI Sbjct: 1378 PRGPLGDPGPRGP----PGLPGTAMKGDKGDRGER----------GPPGPGEGGIAPGEP 1423 Query: 405 GAGGFPGF----------------GVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQA 448 G G PG G G PG+ G PG G G G PG I P+ Sbjct: 1424 GLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPG-AIGPKGDR 1482 Query: 449 AAAAKAAKYGV----GTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAP 504 + G G P A ++ +PGV PG A G PG Sbjct: 1483 GFPGPLGEAGEKGERGPPGPAGSRG---------LPGVAGRPG---AKGPEGPPGPTGRQ 1530 Query: 505 GVGVAPGVGVAPGVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVG 563 G PG P V V P + GP G A A G +PG G Sbjct: 1531 GEKGEPGRPGDPAV-VGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKG 1589 Query: 564 VPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGV 623 PG G GL AG PG PG PG G G +G G G V Sbjct: 1590 DPG---DRGPIGLTGRAGPPGDSGPPGE----------KGDPGRPGPPGPVGPRGRDGEV 1636 Query: 624 VGAGPAAAAAAAKAAAKAAQFGLVGAAGL-GGLG-VGGLGVPGVGGLGGIPPAAAAKAAK 681 G KA + GL GA G+ G +G G G PG G G P ++ K Sbjct: 1637 GEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPK--- 1693 Query: 682 YGVAARPGFGLSPIFPGGACLGKACGRKRK 711 G PG P P G + G + K Sbjct: 1694 -GDRGEPG----PPGPPGRLVDTGPGAREK 1718 Score = 91.7 bits (226), Expect = 2e-18 Identities = 155/545 (28%), Positives = 184/545 (33%), Gaps = 168/545 (30%) Query: 23 PSRPG--GVPGAI-PGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGL 79 P PG G+PG + P G PG PG + L PG K K PGGLAG +G Sbjct: 2274 PGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGL------PGAKGEKGAPGGLAGDLVGE-- 2325 Query: 80 GAFPAVTFPGAL----VPGGVADAAAAYKAAKAGA----GLGGVPGVGGLGVSAAPSVPG 131 PGA +PG + A +A + G G G PG G VPG Sbjct: 2326 --------PGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPG 2377 Query: 132 AVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGG-- 189 + PG PG +GLPG LPGA PGV PG TG + PG G Sbjct: 2378 S----PGPPGPPGVKGDLGLPG------LPGA--PGVVGFPG-QTGPRGEMGQPGPSGER 2424 Query: 190 AFAGIPG----VGPFGGPQPGVPLGYP----IKAPKLPGGYGLPYTTGKL---------- 231 AG PG GP G P P +G P +K K G GLP G+ Sbjct: 2425 GLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDG 2484 Query: 232 -PYGYGPGGVAGAAGKAGYPTGTG-----------------VGPQAAAAAAAKAAAKFGA 273 P GP G+ G G G G +GP A + Sbjct: 2485 RPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPR 2544 Query: 274 GAAGVLPGVGGAGVPGVPGA-----------IPGIGGIAGV-GTPAAAAAAAAAAKAAKY 321 G G G G PG G+ +PG+ G+ G G P AA K Sbjct: 2545 GLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKD 2604 Query: 322 GAAAGLVPG-----------GPGFGPGVVGVPGA-GVPG-------VGVPGA-------- 354 G VPG GP G GV GA G+ G G PG Sbjct: 2605 G-----VPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKG 2659 Query: 355 --GIPVVPG-AGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPG 411 G P VPG +G PG G++ P+ + G + G G P G GGFPG Sbjct: 2660 EMGEPGVPGQSGAPGKE--GLIGPKGDRGFDGQPGPKGDQGEKGERGTP----GIGGFPG 2713 Query: 412 FG-------------------------------------VGVGGIPGVAGVPGVGGVPGV 434 VG G+PG G G G PG Sbjct: 2714 PSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGP 2773 Query: 435 GGVPG 439 G G Sbjct: 2774 AGPRG 2778 Score = 68.9 bits (167), Expect = 2e-11 Identities = 92/309 (29%), Positives = 113/309 (36%), Gaps = 31/309 (10%) Query: 415 GVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAA 474 G G PG G+ G G PG G+PG +P Q + AK G P A + A Sbjct: 1254 GQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRA 1313 Query: 475 QFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGV--GVAPGIGPG--GVA 530 PG APG+ +PG+ PG PG G PG V G GPG G Sbjct: 1314 G---NPGTPGAPGLKGSPGL---PGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRK 1367 Query: 531 AAAKSAAKVAAKAQLRAAAGLG-AGIPGLGV--------GVGVPGLGVGA------GVPG 575 + + L G G+PG + G PG G G G+PG Sbjct: 1368 GDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPG 1427 Query: 576 LGVGAGVPGFGAVPGALAAAKAAKYGA-AVPGVLGGLGALGGVGIPGGVVGAGPAAAAAA 634 L G G PG ++ GA +PG G G G G PG + G Sbjct: 1428 LPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGP 1487 Query: 635 AKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSP 694 A + + G G AG GL G G PG G G PP + + G RPG P Sbjct: 1488 LGEAGEKGERGPPGPAGSRGL-PGVAGRPGAKGPEG-PPGPTGRQGEKGEPGRPG---DP 1542 Query: 695 IFPGGACLG 703 G A G Sbjct: 1543 AVVGPAVAG 1551 >gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens] Length = 1714 Score = 143 bits (361), Expect = 5e-34 Identities = 207/717 (28%), Positives = 258/717 (35%), Gaps = 113/717 (15%) Query: 23 PSRPGGVPGAI----PGGVPGGVFYPGA-GLGALGGGALGPGGKPLKPVPGGLAGAGLGA 77 P P G+PG P G+PG PG GL G PG P +PVPG GL Sbjct: 499 PPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQPVPGEKGDQGLSG 558 Query: 78 -----------GLGAFPAVT-FPGAL-VPGGVAD-AAAAYKAAKAGAGLGGVPG-VGGLG 122 GL P + PG +PG + + Y + AG G PG G G Sbjct: 559 LMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQG 618 Query: 123 VSAAPSVPGAVVPQ-----PGAGVKPGKVPGVGLPGVYPGGVLPGARFP-GVGVLPGVPT 176 +P G + P+ PG K G G PG + G R P G+ PG+ Sbjct: 619 FIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDF------GDRGPAGLDGSPGLVG 672 Query: 177 GAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYG 236 G G P PG+ G+ + +GP G P P+G L G GLP G G Sbjct: 673 GTG-PPGFPGLRGSVGPVGPIGPAGIPG---PMG-------LSGNKGLPGIKG----DKG 717 Query: 237 PGGVAGAAGKAGYPTGTG-VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG--A 293 G AG G+ GYP G VG K+ G G+ G G G PG Sbjct: 718 EQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIG 777 Query: 294 IPGIGGIAGV-------GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AG 345 IPG G G G P + GA L P G G G PG G Sbjct: 778 IPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEG 837 Query: 346 VPG-VGVPG--AGIPVVPGAGIPG-AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPT 401 + G VG G I G+PG + G + + + G + +G G P Sbjct: 838 LKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPG 897 Query: 402 Y--GVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAK--Y 457 +G G PG VG G PG G G G G G+ G Q AK K Sbjct: 898 VPGPIGPLGLPGH-VGARGPPGSQGPKGQRGSRGPDGLLG------EQGIQGAKGEKGDQ 950 Query: 458 GVGTPAAAAAKAAAKAAQ-FGLVPGVGVAPGVGVAPGVGVAPGV-GLAPGVGVAPGVGVA 515 G P K + F PG+ PG G+ PG+ GL VG +G+ Sbjct: 951 GKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGME 1010 Query: 516 PGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPG 575 GP G + + AK + A +G G G PGL G PG Sbjct: 1011 ---------GPPGTEGESGLQGEPGAKGDVGTAGSVG--------GTGEPGLRGEPGAPG 1053 Query: 576 LGVGAGVPGFGAVPG--ALAAAKAAKYGAAVPGVLGGLGALGGVGIPG--GVVG------ 625 G G VPG L K +PG++G LG G G+PG G+VG Sbjct: 1054 EEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRG 1113 Query: 626 ----------AGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIP 672 GP + K + G GA G G VG LG+ G G GIP Sbjct: 1114 RPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRG-AVGHLGLMGPDGEPGIP 1169 Score = 116 bits (290), Expect = 8e-26 Identities = 206/715 (28%), Positives = 254/715 (35%), Gaps = 127/715 (17%) Query: 26 PGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGA-GLGAGLGAFPA 84 P G PG P G PG + PG G LG G P P GL G G +GAF Sbjct: 763 PSGPPG--PEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPP---GLKGTQGEEGPIGAFGE 817 Query: 85 VT---------FPGALVPGG----VADAAAAYKAAKAG-AGLGGVPGV-GGLGVSAAPSV 129 + + G P G V D K + G GL G G+ G +G Sbjct: 818 LGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGS 877 Query: 130 PGAVVPQ--------PGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVK 181 PG + PQ PG PG + +GLPG PG++ P P G + Sbjct: 878 PGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGE 937 Query: 182 PKAPGVGGAFAGIPGVGPFG----GPQPGVPLGYPIKAPKLPGGYGLPYTTGK--LPYGY 235 G G GP G PG G+ K PG GLP +TG LP Sbjct: 938 QGIQGAKGEKGDQGKRGPHGLIGKTGNPG-ERGFQGK----PGLQGLPGSTGDRGLP--- 989 Query: 236 GPGGVAGAAGKAGYPTGTGV----GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVP 291 G G+ G G G P G+ G + + + AK G AG + G G G+ G P Sbjct: 990 GEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEP 1049 Query: 292 GAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPGV- 349 GA PG G+ G K G VPGG G PG G G G+PG+ Sbjct: 1050 GA-PGEEGLQG-----------------KDGLKG--VPGGRGL-PGEDGEKGEMGLPGII 1088 Query: 350 ---------GVPGA-GIPVVPGA-GIPGA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVG 397 G+PG GI +PG G PG G + P + K G G Sbjct: 1089 GPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGAR 1148 Query: 398 GIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKY 457 G GA G G +G G PG+ G G G PG G+PG K K Sbjct: 1149 GTR----GAVGHLGL-MGPDGEPGIPGYRGHQGQPGPSGLPG------------PKGEKG 1191 Query: 458 GVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGV-GLAPGVGVAPGVGVAP 516 G + PG PG G PG G VGV PG+ A Sbjct: 1192 YPGEDSTVLGP-----------PGPRGEPGPVGDQGERGEPGAEGYKGHVGV-PGLRGAT 1239 Query: 517 GVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGA-GIPGLGVGVGVPGLGVGAGVPG 575 G PG PG + K + + G G PG G+PGL G G Sbjct: 1240 GQQGPPG-EPG-------DQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKG 1291 Query: 576 LGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAA 635 + G G PG + K G +PG+ GG G G G PG G + + Sbjct: 1292 IQGYHGADGISGNPGKIGPP--GKQG--LPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSP 1347 Query: 636 KAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGF 690 + GL G G+ G G G G G G P + +YGV GF Sbjct: 1348 GIQGPKGEQGLPGQPGIQGKR-GHRGAQGDQGPCG-DPGLKGQPGEYGVQGLTGF 1400 Score = 98.2 bits (243), Expect = 2e-20 Identities = 186/634 (29%), Positives = 221/634 (34%), Gaps = 75/634 (11%) Query: 26 PGGVPGAI-PGGVPG-----------------GVFYPGAGLGALG-GGALGPGGKPLKPV 66 P GVPG I P G+PG G P LG G GA G G K Sbjct: 895 PPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRG 954 Query: 67 PGGLAGAGLGAGLGAFPAVTFPGAL-VPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSA 125 P GL G G F PG +PG D + G G V G +G+ Sbjct: 955 PHGLIGKTGNPGERGFQGK--PGLQGLPGSTGDRGLPGEPGLRGLQ-GDVGPPGEMGMEG 1011 Query: 126 APSVPGAVVPQPGAGVK-----PGKVPGVGLPGVYPGGVLPGAR-FPGVGVLPGVPTGAG 179 P G Q G K G V G G PG+ PG G L GVP G G Sbjct: 1012 PPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRG 1071 Query: 180 VKPKAPGVGGAFAGIPGV-GPFG-GPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGP 237 + P G G G+PG+ GP G Q G+P P +PG G P Sbjct: 1072 L-PGEDGEKGEM-GLPGIIGPLGRSGQTGLP--GPEGIVGIPGQRGRP------------ 1115 Query: 238 GGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGI 297 G G G+ G PTG VG + K+ K G G + +G G G PG IPG Sbjct: 1116 -GKKGDKGQIG-PTGE-VGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPG-IPGY 1171 Query: 298 GGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPGV-GVPG-A 354 G G P+ K + L P GP PG VG G G PG G G Sbjct: 1172 RGHQGQPGPSGLPGPKGE-KGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHV 1230 Query: 355 GIPVVPGA----GIPGA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYG--VGAG 407 G+P + GA G PG G + + K GA G GIP +G Sbjct: 1231 GVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPK 1290 Query: 408 GFPGF--GVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAA 465 G G+ G+ G PG G PG G+PG+ G PG A K + G+P Sbjct: 1291 GIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQ 1350 Query: 466 AAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPG-VGVAPGVGVAPGI 524 K + GL PG G G G PG+ PG GV G Sbjct: 1351 GPK-----GEQGL-PGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQGFP 1404 Query: 525 GPGGVAAAAKSAAKVAAKAQLRAAAGLG----AGIPGLGVGVGVPGLGVGAGVPGLGVGA 580 GP G A K + G GI G G G G G Sbjct: 1405 GPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGPR 1464 Query: 581 GVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGAL 614 G PG PGA K AA+ ++ AL Sbjct: 1465 GQPGPPGPPGAPGPRKQMDINAAIQALIESNTAL 1498 Score = 75.5 bits (184), Expect = 2e-13 Identities = 125/497 (25%), Positives = 168/497 (33%), Gaps = 98/497 (19%) Query: 230 KLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPG 289 ++ Y GP G G G G P G GP G G+ G G+PG Sbjct: 483 EMEYLRGPKGDTGPPGPPG-PAGIP-GPSGKR------------GPRGIPGPHGNPGLPG 528 Query: 290 VPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AGVPG 348 +PG G P + + G + + P G G+ G PG G+PG Sbjct: 529 LPGP------KGPKGDPGFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPG 582 Query: 349 -VGVPG----AGIPVVPG-------------------AGIPGAA----------VPGVVS 374 G+PG G P PG G PG A +PG+ Sbjct: 583 EQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRG 642 Query: 375 PEAAAKAAAKAAKYGARPGVGVGGIP--TYGVGAGGFPGF--GVGVGGIPGVAGVPGVGG 430 + +G R G+ G P G G GFPG VG G G AG+PG G Sbjct: 643 KKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMG 702 Query: 431 VPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGV 490 + G G+PG+ Q A +G P K A G+ PG+ Sbjct: 703 LSGNKGLPGIKGDKGEQGTAGE------LGEPGYPGDKGAV---------GLPGPPGMRG 747 Query: 491 APGVGVAPGVGLAPGVGVAPGVGVAPG-VGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAA 549 G G G PG PG +G+ GP G + Sbjct: 748 KSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGP----------- 796 Query: 550 GLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLG 609 G PGL G G G G G G+ PG + K G +G Sbjct: 797 ---PGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPG----PEGLKGEVGDQGNIG 849 Query: 610 GLGALGGVGIPG--GVVGA-GPAAAAAAAKAAAKAAQFGLVGAAGLGGL--GVGGLGVPG 664 +G G VG+PG G+ G+ G + + G++G G G+ +G LG+PG Sbjct: 850 KIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPG 909 Query: 665 VGGLGGIPPAAAAKAAK 681 G G P + K + Sbjct: 910 HVGARGPPGSQGPKGQR 926 Score = 66.6 bits (161), Expect = 7e-11 Identities = 79/287 (27%), Positives = 103/287 (35%), Gaps = 24/287 (8%) Query: 410 PGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKA 469 P G G PG AG+PG G G G+PG +P K K G P + + Sbjct: 490 PKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPK---GDPGFSPGQP 546 Query: 470 AAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGV 529 + G+ PG+ G+ PG+ PG P G A +G G G+ Sbjct: 547 VPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIP--GFAGNIGSPGYPGRQGL 604 Query: 530 AAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVP 589 A + A+ + G PG +G G G+PG+ G G P Sbjct: 605 AGPEGNPGPKGAQGFI--------GSPGEAGQLGPEG---ERGIPGIRGKKGFKGRQGFP 653 Query: 590 GALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGA 649 G A + PG++GG G G G+ G V GP A + GL G Sbjct: 654 GDFGDRGPAGLDGS-PGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGI 712 Query: 650 AG-LGGLGVGG-LGVPGVGGLGGI-----PPAAAAKAAKYGVAARPG 689 G G G G LG PG G G PP K+ G PG Sbjct: 713 KGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPG 759 >gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo sapiens] Length = 1818 Score = 141 bits (356), Expect = 2e-33 Identities = 224/762 (29%), Positives = 264/762 (34%), Gaps = 139/762 (18%) Query: 25 RPG--GVPGAIPG-GVPGGVFYPGA-------GLGALGG-----GALGPGGKPLKPVPGG 69 +PG G PGA G G+PG PGA GL L G G GP G P P G Sbjct: 587 KPGKRGRPGADGGRGMPGE---PGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDG 643 Query: 70 LAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGL-GVSAAPS 128 + G G P P L+ G G PG G+ GV P Sbjct: 644 MRGEDGEIGPRGLPGEAGPRGLL---------------GPRGTPGAPGQPGMAGVDGPPG 688 Query: 129 VPGAVVPQ--PGAGVKPGKVPGVGLPGVYPGGVL--PGARFP-GVGVLPGVPTGAGVKPK 183 G + PQ PG + G GLPG P G + PG + P G L G+P GA P Sbjct: 689 PKGNMGPQGEPGPPGQQGNPGPQGLPG--PQGPIGPPGEKGPQGKPGLAGLP-GADGPPG 745 Query: 184 APGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPK----LPGGYGLPYTTGK-----LPYG 234 PG G +GP P P P+GYP P+ G GL + G+ P Sbjct: 746 HPGKEGQSGEKGALGP---PGPQGPIGYP--GPRGVKGADGVRGLKGSKGEKGEDGFPGF 800 Query: 235 YGPGGVAGAAGKAGY--PTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG 292 G G+ G G+ G P G GP+ A +G AG +G G+PG PG Sbjct: 801 KGDMGLKGDRGEVGQIGPRGED-GPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPG 859 Query: 293 AIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGP-------------------- 332 G G P A A A K G P GP Sbjct: 860 RQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSG 919 Query: 333 GFGP-------------GVVGVPGAGVPGVGVPGA-GIPVVPG----AGIPGAAVP---- 370 G GP G VG PG P G PG G+P PG G G P Sbjct: 920 GDGPPGPPGERGPQGPQGPVGFPGPKGP-PGPPGKDGLPGHPGQRGETGFQGKTGPPGPG 978 Query: 371 GVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFG--VGVGGIPGVAGVPGV 428 GVV P+ + G R G G P G G PG G G PG G+ G Sbjct: 979 GVVGPQG---PTGETGPIGERGHPGPPGPP----GEQGLPGAAGKEGAKGDPGPQGISGK 1031 Query: 429 GGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGV 488 G G+ G PG P AQ A K + G P + +A G+ PG Sbjct: 1032 DGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGP 1091 Query: 489 GVAPGVGVAPGVGLAPG----VGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQ 544 PG G APG G A GV VG+ GP G ++ Q Sbjct: 1092 QGPPGPAGEKG---APGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQ 1148 Query: 545 LRAAAGLG----AGIPGLGVGVGVPGLGVGAGVPG----LGV-----GAGVPGFGAVPGA 591 + G G PGL VG PG+ G G PG G+ G GF PG Sbjct: 1149 KGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGP 1208 Query: 592 LAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAG 651 + PG G G +G +G PG GP A G VG G Sbjct: 1209 IGLQGL----PGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVG 1264 Query: 652 LGGL--GVGGLGVPGVGGLGGIPPAAAAK--AAKYGVAARPG 689 G G G PG G+GG K A G A PG Sbjct: 1265 EKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPG 1306 Score = 136 bits (342), Expect = 8e-32 Identities = 245/857 (28%), Positives = 280/857 (32%), Gaps = 228/857 (26%) Query: 23 PSRPGGVPGAI-PGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGA 81 P P G PG P G PG PGA GP G P K G GA LG G Sbjct: 716 PQGPIGPPGEKGPQGKPGLAGLPGAD---------GPPGHPGKEGQSGEKGA-LGPP-GP 764 Query: 82 FPAVTFPGALVPGGV--ADAAAAYKAAKAGAGLGGVPGV-GGLGVSAAPSVPGAVVPQ-- 136 + +PG P GV AD K +K G G PG G +G+ G + P+ Sbjct: 765 QGPIGYPG---PRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGE 821 Query: 137 ---------------PGAGVKPGKVPGVGLPGV--YPG--GVLPGARFPGVGVLPGVPTG 177 PG + G+ +G+PG+ YPG G FPG G Sbjct: 822 DGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGA 881 Query: 178 AGVKPKA-----------------------PGVGGAFAGIPGVGPFG--GPQ-PGVPLGY 211 GV K PG G G GP G GPQ P P+G+ Sbjct: 882 RGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGF 941 Query: 212 PIKA--PKLPGGYGLPYTTGKL-------------PYGY----GPGGVAGAAGKAGYPTG 252 P P PG GLP G+ P G GP G G G+ G+P Sbjct: 942 PGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGP 1001 Query: 253 TGV-GPQAAAAAAAKAAAKFGAGAAGV-----------------LPGV-------GGAGV 287 G G Q AA K AK G G+ LPG GG G Sbjct: 1002 PGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGP 1061 Query: 288 PGVPGAI--PGIGGIAG----VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGV--- 338 G PG + PG G AG +G P A + GA P GP GV Sbjct: 1062 QGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP 1121 Query: 339 VGVPG----AGVPG-------VGVPGA----------GIPVVPG----AGIPG-AAVPGV 372 VG+PG AG PG +G PG G P PG G PG A G Sbjct: 1122 VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGE 1181 Query: 373 VSPEAAAKAAAKAAKYGAR-----PG-VGVGGIP--------TYGVGAGGFPG------- 411 P + GAR PG +G+ G+P VG G PG Sbjct: 1182 PGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGP 1241 Query: 412 -------------------FGVGVGGIPGVAGVPGVGGVPGVGGVPGV-GISPEA--QAA 449 GVG G PG AG PG G GVGG G G EA A Sbjct: 1242 QGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGA 1301 Query: 450 AAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVA 509 A AK G P K F PG PG GVG G PG Sbjct: 1302 AGPPGAK---GPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGP 1358 Query: 510 PGVGVAPGVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRAAAGLGA--------------- 553 PG G PG GP G A A + AK + A G Sbjct: 1359 PGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGP 1418 Query: 554 ----GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALA--------------AA 595 GIPG G+PG G PG G+PG PG+ Sbjct: 1419 EGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGE 1478 Query: 596 KAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL 655 + K +PG G GA G GIPG GP G G AG Sbjct: 1479 QGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAG---- 1534 Query: 656 GVGGLGVPGVGGLGGIP 672 G G+PG G G P Sbjct: 1535 QKGDSGLPGPPGSPGPP 1551 Score = 132 bits (332), Expect = 1e-30 Identities = 199/656 (30%), Positives = 226/656 (34%), Gaps = 88/656 (13%) Query: 22 HPSRPG--GVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGL 79 HP + G G G PGGV P G G +G G P P P G GL Sbjct: 959 HPGQRGETGFQGKTGPPGPGGVVGPQGPTGETG--PIGERGHPGPPGPPG--EQGLPGAA 1014 Query: 80 GAFPAVTFPGALVPGGVA--DAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVVPQP 137 G A PG P G++ D A + GL G G GL P P V P Sbjct: 1015 GKEGAKGDPG---PQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSP 1071 Query: 138 GAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGV 197 G G +GLPG PG + P PG P G P G G AG GV Sbjct: 1072 GERGSAGTAGPIGLPG------RPGPQGP-----PG-PAGEKGAPGEKGPQGP-AGRDGV 1118 Query: 198 -GPFGGPQPGVPLGYP--------IKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAG 248 GP G P P P G P I P G G G GP G+ G G G Sbjct: 1119 QGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPP----GPPGLQGPVGAPG 1174 Query: 249 YPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPA 307 G G GP+ + + G G +G G+PG PG G + +G P Sbjct: 1175 IAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPG 1234 Query: 308 AAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPG-AGIPVVPG-AGIP 365 G P GP PG VG G GV G PG AG P PG AG+ Sbjct: 1235 PPGPRGPQGPNGADG------PQGP---PGSVGSVG-GVGEKGEPGEAGNPGPPGEAGVG 1284 Query: 366 GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGV 425 G G + A A GA+ G G P G GFPG G G PG AG Sbjct: 1285 GPK--GERGEKGEAGPPGAAGPPGAKGPPGDDG-PKGNPGPVGFPG-DPGPPGEPGPAGQ 1340 Query: 426 PGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAA------KAAAKAAQFGLV 479 GVGG G G PG P A G P AA A K A A Sbjct: 1341 DGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGP 1400 Query: 480 PGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG-IGPGGVAAAAKSAAK 538 PG G G G+ PG G+ A G PG +GP G+ Sbjct: 1401 PGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGS 1460 Query: 539 VAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAA 598 K G PGL +G PG G GL G PG A Sbjct: 1461 KGEK-----------GHPGLIGLIGPPGEQGEKGDRGLPGTQGSPG-------------A 1496 Query: 599 KYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGG 654 K +PG G LG G G+PG GP + A + GL G G G Sbjct: 1497 KGDGGIPGPAGPLGPPGPPGLPG---PQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1549 Score = 110 bits (274), Expect = 6e-24 Identities = 205/729 (28%), Positives = 249/729 (34%), Gaps = 131/729 (17%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAF 82 P+ P G+ G P G+ G PG G GP G+P P GL G G Sbjct: 458 PAGPAGIMG--PPGLQGPTGPPG------DPGDRGPPGRPGLPGADGLPGP---PGTMLM 506 Query: 83 PAVTFPGALVPGGVADAAAAYKAA---KAGAGLGGVPGVGGLGVSAAPSVPGAVVPQPGA 139 + G G A A A +A L G PG GL Sbjct: 507 LPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTG---------------- 550 Query: 140 GVKPGKVPGVGLPGVYPGGVLPGARFP-GVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVG 198 +PG V G G G PG + P GV PG PTG K PG G G+PG Sbjct: 551 --RPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPG-PTGKPGKRGRPGADGG-RGMPGEP 606 Query: 199 PFGGPQ-----PGVP--LGY-----PIKAPKLPGGYGLPYTTGK-----LPYGYGPGGVA 241 G + PG+P G+ P P PG G+ G+ LP GP G+ Sbjct: 607 GAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLL 666 Query: 242 GAAGKAGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAI--PGIG 298 G G G P G+ G + G G G G+PG G I PG Sbjct: 667 GPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEK 726 Query: 299 GIAG----VGTPAAAAAAAAAAKAAKYGAAAGLVPGGP----GFGPGVVGVPGA-GVPGV 349 G G G P A K + G L P GP G+ PG GV GA GV G+ Sbjct: 727 GPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGY-PGPRGVKGADGVRGL 785 Query: 350 ----------GVPG--AGIPVVPGAGIPGAAVP-GVVSPEAAAKAA------AKAAKYGA 390 G PG + + G G P G PE A + + G Sbjct: 786 KGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGE 845 Query: 391 RPGVGVGGIPTY-----GVGAGGFPGF--GVGVGGIPGVAGVPGVGGVPGVGGVPGVGIS 443 + +GV G+P Y G+ GFPGF G G GVAG PG G G G G + Sbjct: 846 KGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGA 905 Query: 444 PEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPG---- 499 K G G P + PG PG G+ PG Sbjct: 906 RGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGE 965 Query: 500 VGL-----APGVGVAPG----VGVAPGVGVAPGIGPGG-------VAAAAKSAAKVAAKA 543 G PG G G G +G GP G AA K AK Sbjct: 966 TGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGP 1025 Query: 544 QLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAA 603 Q + AG+ G G+PG G PGL G G G PG + + Sbjct: 1026 QGISGKDGPAGLRGFPGERGLPG---AQGAPGLKGGEGPQG---PPGPVGS--------- 1070 Query: 604 VPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVP 663 PG G G G +G+PG GP A A + G G G+ G +G+P Sbjct: 1071 -PGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGV----QGPVGLP 1125 Query: 664 GVGGLGGIP 672 G G G P Sbjct: 1126 GPAGPAGSP 1134 Score = 92.0 bits (227), Expect = 2e-18 Identities = 162/522 (31%), Positives = 181/522 (34%), Gaps = 120/522 (22%) Query: 26 PGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAV 85 PG G P G PG V PG A G GP G P +P P G G G Sbjct: 1053 PGLKGGEGPQGPPGPVGSPGERGSA---GTAGPIGLPGRPGPQGPPGPAGEKGA------ 1103 Query: 86 TFPGALVPGGVA--DAAAAYKAAKAGAGLGGVPGVGG-LGVSAAPSVPGAVVP--QPGAG 140 PG P G A D AG G PG G G P G+ + G Sbjct: 1104 --PGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPP 1161 Query: 141 VKPGKVPGVGLPGVYPGGVLPGARFP----------GVGVLPGVPTGAGVK--PKAPGVG 188 PG VG PG+ G PG R G PG P G++ P PG Sbjct: 1162 GPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEK 1221 Query: 189 GAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAG 248 G + +GP G P P P G P A G G P + G + G G G G AG G Sbjct: 1222 GENGDVGPMGPPGPPGPRGPQG-PNGAD---GPQGPPGSVGSVG-GVGEKGEPGEAGNPG 1276 Query: 249 YPTGTGVG--------------PQAAAAAAAKA-----AAKFGAGAAGV----------- 278 P GVG P AA AK K G G Sbjct: 1277 PPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPG 1336 Query: 279 ---LPGVGGA----GVPGVPGAIPGIGGIAGVGTP--------AAAAAAAAAAKAAKYGA 323 GVGG G PG PG PG G AG P AA A K AK A Sbjct: 1337 PAGQDGVGGDKGEDGDPGQPGP-PGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEA 1395 Query: 324 AAGLVPGGPG-FGP-GVVGVPGA----GVPGV----GVPGA----------GIPVVPGA- 362 A PG G GP G G PG G+PG G+PGA G P +PG Sbjct: 1396 GAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLK 1455 Query: 363 GIPGA-------AVPGVVSP--EAAAKAAAKAAKYGARPGV-GVGGIPTYG--VGAGGFP 410 G PG+ + G++ P E K PG G GGIP +G G P Sbjct: 1456 GDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPP 1515 Query: 411 GF--------GVGVGGIPGVAGVPGVGGVPGVGGVPGVGISP 444 G G G G G G+ G PG G PG I P Sbjct: 1516 GLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQP 1557 Score = 89.0 bits (219), Expect = 1e-17 Identities = 146/519 (28%), Positives = 177/519 (34%), Gaps = 95/519 (18%) Query: 182 PKAPGVGGAFAGIPGV-GPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGK---LPYGYGP 237 P P G PG+ GP G P G P + P LPG GLP G LP+ YG Sbjct: 455 PPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGR-PGLPGADGLPGPPGTMLMLPFRYGG 513 Query: 238 GGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGI 297 G G PT + Q A A A A+ + G PG + Sbjct: 514 DGSKG-------PT---ISAQEAQAQAILQQARIA--------------LRGPPGPMGLT 549 Query: 298 GGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIP 357 G VG P ++ A + G P GP PG G PGA G G+P Sbjct: 550 GRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGAD------GGRGMP 603 Query: 358 VVPGA----GIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFG 413 PGA G G +PG+ + G G+ G +G G PG Sbjct: 604 GEPGAKGDRGFDG--LPGLPGDKGHRGERGPQGPPGPPGDDGMRG-EDGEIGPRGLPG-E 659 Query: 414 VGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKA 473 G G+ G G PG G PG+ GV G K G P Sbjct: 660 AGPRGLLGPRGTPGAPGQPGMAGVDG---------PPGPKGNMGPQGEPGP--------- 701 Query: 474 AQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAA 533 PG PG PG G G PG+ PG PG PG + Sbjct: 702 ------PGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPG-HPGKEGQSG 754 Query: 534 KSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPG-LGV-GA-GVPGLGVGAGVPGFGAVPG 590 + A G PG +G PG GV GA GV GL G G PG Sbjct: 755 EKGA---------------LGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPG 799 Query: 591 ALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAA 650 K + G G +G +G G G G A + +A + G +G Sbjct: 800 -------FKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVP 852 Query: 651 GLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPG 689 GL G G G G G G P A K A+ GVA +PG Sbjct: 853 GLPGY-PGRQGPKGSTGFPGFPGANGEKGAR-GVAGKPG 889 Score = 64.3 bits (155), Expect = 4e-10 Identities = 92/316 (29%), Positives = 108/316 (34%), Gaps = 24/316 (7%) Query: 392 PGVGVGGIPTYGVGAG--GFPGFG--VGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQ 447 PG+ V G P AG G PG G G PG G PG G+PG G+PG P Sbjct: 448 PGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPG---PPGTM 504 Query: 448 AAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVG 507 + G P +A +A A+A + PG G+ PG PG Sbjct: 505 LMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPG---PMGLTGRPGPVGGPGSS 561 Query: 508 VAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGL 567 A G PG GP GV K + R A G G+PG G G Sbjct: 562 GAKGESGDPGPQ-----GPRGVQGPPGPTGKPGKRG--RPGADGGRGMPGEPGAKGDRGF 614 Query: 568 GVGAGVPGLGVGAGVPGFGAVPG-----ALAAAKAAKYGAAVPGVLGGLGALGGVGIPGG 622 G+PG G G PG + +PG G G LG G PG Sbjct: 615 DGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGA 674 Query: 623 VVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKY 682 G A G G G G G G+PG G G PP K Sbjct: 675 PGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQG-NPGPQGLPGPQGPIG-PPGEKGPQGKP 732 Query: 683 GVAARPGFGLSPIFPG 698 G+A PG P PG Sbjct: 733 GLAGLPGADGPPGHPG 748 >gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo sapiens] Length = 1767 Score = 141 bits (356), Expect = 2e-33 Identities = 224/762 (29%), Positives = 264/762 (34%), Gaps = 139/762 (18%) Query: 25 RPG--GVPGAIPG-GVPGGVFYPGA-------GLGALGG-----GALGPGGKPLKPVPGG 69 +PG G PGA G G+PG PGA GL L G G GP G P P G Sbjct: 536 KPGKRGRPGADGGRGMPGE---PGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDG 592 Query: 70 LAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGL-GVSAAPS 128 + G G P P L+ G G PG G+ GV P Sbjct: 593 MRGEDGEIGPRGLPGEAGPRGLL---------------GPRGTPGAPGQPGMAGVDGPPG 637 Query: 129 VPGAVVPQ--PGAGVKPGKVPGVGLPGVYPGGVL--PGARFP-GVGVLPGVPTGAGVKPK 183 G + PQ PG + G GLPG P G + PG + P G L G+P GA P Sbjct: 638 PKGNMGPQGEPGPPGQQGNPGPQGLPG--PQGPIGPPGEKGPQGKPGLAGLP-GADGPPG 694 Query: 184 APGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPK----LPGGYGLPYTTGK-----LPYG 234 PG G +GP P P P+GYP P+ G GL + G+ P Sbjct: 695 HPGKEGQSGEKGALGP---PGPQGPIGYP--GPRGVKGADGVRGLKGSKGEKGEDGFPGF 749 Query: 235 YGPGGVAGAAGKAGY--PTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG 292 G G+ G G+ G P G GP+ A +G AG +G G+PG PG Sbjct: 750 KGDMGLKGDRGEVGQIGPRGED-GPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPG 808 Query: 293 AIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGP-------------------- 332 G G P A A A K G P GP Sbjct: 809 RQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSG 868 Query: 333 GFGP-------------GVVGVPGAGVPGVGVPGA-GIPVVPG----AGIPGAAVP---- 370 G GP G VG PG P G PG G+P PG G G P Sbjct: 869 GDGPPGPPGERGPQGPQGPVGFPGPKGP-PGPPGKDGLPGHPGQRGETGFQGKTGPPGPG 927 Query: 371 GVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFG--VGVGGIPGVAGVPGV 428 GVV P+ + G R G G P G G PG G G PG G+ G Sbjct: 928 GVVGPQG---PTGETGPIGERGHPGPPGPP----GEQGLPGAAGKEGAKGDPGPQGISGK 980 Query: 429 GGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGV 488 G G+ G PG P AQ A K + G P + +A G+ PG Sbjct: 981 DGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGP 1040 Query: 489 GVAPGVGVAPGVGLAPG----VGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQ 544 PG G APG G A GV VG+ GP G ++ Q Sbjct: 1041 QGPPGPAGEKG---APGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQ 1097 Query: 545 LRAAAGLG----AGIPGLGVGVGVPGLGVGAGVPG----LGV-----GAGVPGFGAVPGA 591 + G G PGL VG PG+ G G PG G+ G GF PG Sbjct: 1098 KGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGP 1157 Query: 592 LAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAG 651 + PG G G +G +G PG GP A G VG G Sbjct: 1158 IGLQGL----PGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVG 1213 Query: 652 LGGL--GVGGLGVPGVGGLGGIPPAAAAK--AAKYGVAARPG 689 G G G PG G+GG K A G A PG Sbjct: 1214 EKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPG 1255 Score = 136 bits (342), Expect = 8e-32 Identities = 245/857 (28%), Positives = 280/857 (32%), Gaps = 228/857 (26%) Query: 23 PSRPGGVPGAI-PGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGA 81 P P G PG P G PG PGA GP G P K G GA LG G Sbjct: 665 PQGPIGPPGEKGPQGKPGLAGLPGAD---------GPPGHPGKEGQSGEKGA-LGPP-GP 713 Query: 82 FPAVTFPGALVPGGV--ADAAAAYKAAKAGAGLGGVPGV-GGLGVSAAPSVPGAVVPQ-- 136 + +PG P GV AD K +K G G PG G +G+ G + P+ Sbjct: 714 QGPIGYPG---PRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGE 770 Query: 137 ---------------PGAGVKPGKVPGVGLPGV--YPG--GVLPGARFPGVGVLPGVPTG 177 PG + G+ +G+PG+ YPG G FPG G Sbjct: 771 DGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGA 830 Query: 178 AGVKPKA-----------------------PGVGGAFAGIPGVGPFG--GPQ-PGVPLGY 211 GV K PG G G GP G GPQ P P+G+ Sbjct: 831 RGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGF 890 Query: 212 PIKA--PKLPGGYGLPYTTGKL-------------PYGY----GPGGVAGAAGKAGYPTG 252 P P PG GLP G+ P G GP G G G+ G+P Sbjct: 891 PGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGP 950 Query: 253 TGV-GPQAAAAAAAKAAAKFGAGAAGV-----------------LPGV-------GGAGV 287 G G Q AA K AK G G+ LPG GG G Sbjct: 951 PGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGP 1010 Query: 288 PGVPGAI--PGIGGIAG----VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGV--- 338 G PG + PG G AG +G P A + GA P GP GV Sbjct: 1011 QGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP 1070 Query: 339 VGVPG----AGVPG-------VGVPGA----------GIPVVPG----AGIPG-AAVPGV 372 VG+PG AG PG +G PG G P PG G PG A G Sbjct: 1071 VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGE 1130 Query: 373 VSPEAAAKAAAKAAKYGAR-----PG-VGVGGIP--------TYGVGAGGFPG------- 411 P + GAR PG +G+ G+P VG G PG Sbjct: 1131 PGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGP 1190 Query: 412 -------------------FGVGVGGIPGVAGVPGVGGVPGVGGVPGV-GISPEA--QAA 449 GVG G PG AG PG G GVGG G G EA A Sbjct: 1191 QGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGA 1250 Query: 450 AAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVA 509 A AK G P K F PG PG GVG G PG Sbjct: 1251 AGPPGAK---GPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGP 1307 Query: 510 PGVGVAPGVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRAAAGLGA--------------- 553 PG G PG GP G A A + AK + A G Sbjct: 1308 PGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGP 1367 Query: 554 ----GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALA--------------AA 595 GIPG G+PG G PG G+PG PG+ Sbjct: 1368 EGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGE 1427 Query: 596 KAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL 655 + K +PG G GA G GIPG GP G G AG Sbjct: 1428 QGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAG---- 1483 Query: 656 GVGGLGVPGVGGLGGIP 672 G G+PG G G P Sbjct: 1484 QKGDSGLPGPPGSPGPP 1500 Score = 132 bits (332), Expect = 1e-30 Identities = 199/656 (30%), Positives = 226/656 (34%), Gaps = 88/656 (13%) Query: 22 HPSRPG--GVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGL 79 HP + G G G PGGV P G G +G G P P P G GL Sbjct: 908 HPGQRGETGFQGKTGPPGPGGVVGPQGPTGETG--PIGERGHPGPPGPPG--EQGLPGAA 963 Query: 80 GAFPAVTFPGALVPGGVA--DAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVVPQP 137 G A PG P G++ D A + GL G G GL P P V P Sbjct: 964 GKEGAKGDPG---PQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSP 1020 Query: 138 GAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGV 197 G G +GLPG PG + P PG P G P G G AG GV Sbjct: 1021 GERGSAGTAGPIGLPG------RPGPQGP-----PG-PAGEKGAPGEKGPQGP-AGRDGV 1067 Query: 198 -GPFGGPQPGVPLGYP--------IKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAG 248 GP G P P P G P I P G G G GP G+ G G G Sbjct: 1068 QGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPP----GPPGLQGPVGAPG 1123 Query: 249 YPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPA 307 G G GP+ + + G G +G G+PG PG G + +G P Sbjct: 1124 IAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPG 1183 Query: 308 AAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPG-AGIPVVPG-AGIP 365 G P GP PG VG G GV G PG AG P PG AG+ Sbjct: 1184 PPGPRGPQGPNGADG------PQGP---PGSVGSVG-GVGEKGEPGEAGNPGPPGEAGVG 1233 Query: 366 GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGV 425 G G + A A GA+ G G P G GFPG G G PG AG Sbjct: 1234 GPK--GERGEKGEAGPPGAAGPPGAKGPPGDDG-PKGNPGPVGFPG-DPGPPGEPGPAGQ 1289 Query: 426 PGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAA------KAAAKAAQFGLV 479 GVGG G G PG P A G P AA A K A A Sbjct: 1290 DGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGP 1349 Query: 480 PGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG-IGPGGVAAAAKSAAK 538 PG G G G+ PG G+ A G PG +GP G+ Sbjct: 1350 PGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGS 1409 Query: 539 VAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAA 598 K G PGL +G PG G GL G PG A Sbjct: 1410 KGEK-----------GHPGLIGLIGPPGEQGEKGDRGLPGTQGSPG-------------A 1445 Query: 599 KYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGG 654 K +PG G LG G G+PG GP + A + GL G G G Sbjct: 1446 KGDGGIPGPAGPLGPPGPPGLPG---PQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1498 Score = 110 bits (274), Expect = 6e-24 Identities = 205/729 (28%), Positives = 249/729 (34%), Gaps = 131/729 (17%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAF 82 P+ P G+ G P G+ G PG G GP G+P P GL G G Sbjct: 407 PAGPAGIMG--PPGLQGPTGPPG------DPGDRGPPGRPGLPGADGLPGP---PGTMLM 455 Query: 83 PAVTFPGALVPGGVADAAAAYKAA---KAGAGLGGVPGVGGLGVSAAPSVPGAVVPQPGA 139 + G G A A A +A L G PG GL Sbjct: 456 LPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTG---------------- 499 Query: 140 GVKPGKVPGVGLPGVYPGGVLPGARFP-GVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVG 198 +PG V G G G PG + P GV PG PTG K PG G G+PG Sbjct: 500 --RPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPG-PTGKPGKRGRPGADGG-RGMPGEP 555 Query: 199 PFGGPQ-----PGVP--LGY-----PIKAPKLPGGYGLPYTTGK-----LPYGYGPGGVA 241 G + PG+P G+ P P PG G+ G+ LP GP G+ Sbjct: 556 GAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLL 615 Query: 242 GAAGKAGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAI--PGIG 298 G G G P G+ G + G G G G+PG G I PG Sbjct: 616 GPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEK 675 Query: 299 GIAG----VGTPAAAAAAAAAAKAAKYGAAAGLVPGGP----GFGPGVVGVPGA-GVPGV 349 G G G P A K + G L P GP G+ PG GV GA GV G+ Sbjct: 676 GPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGY-PGPRGVKGADGVRGL 734 Query: 350 ----------GVPG--AGIPVVPGAGIPGAAVP-GVVSPEAAAKAA------AKAAKYGA 390 G PG + + G G P G PE A + + G Sbjct: 735 KGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGE 794 Query: 391 RPGVGVGGIPTY-----GVGAGGFPGF--GVGVGGIPGVAGVPGVGGVPGVGGVPGVGIS 443 + +GV G+P Y G+ GFPGF G G GVAG PG G G G G + Sbjct: 795 KGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGA 854 Query: 444 PEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPG---- 499 K G G P + PG PG G+ PG Sbjct: 855 RGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGE 914 Query: 500 VGL-----APGVGVAPG----VGVAPGVGVAPGIGPGG-------VAAAAKSAAKVAAKA 543 G PG G G G +G GP G AA K AK Sbjct: 915 TGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGP 974 Query: 544 QLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAA 603 Q + AG+ G G+PG G PGL G G G PG + + Sbjct: 975 QGISGKDGPAGLRGFPGERGLPG---AQGAPGLKGGEGPQG---PPGPVGS--------- 1019 Query: 604 VPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVP 663 PG G G G +G+PG GP A A + G G G+ G +G+P Sbjct: 1020 -PGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGV----QGPVGLP 1074 Query: 664 GVGGLGGIP 672 G G G P Sbjct: 1075 GPAGPAGSP 1083 Score = 92.0 bits (227), Expect = 2e-18 Identities = 162/522 (31%), Positives = 181/522 (34%), Gaps = 120/522 (22%) Query: 26 PGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAV 85 PG G P G PG V PG A G GP G P +P P G G G Sbjct: 1002 PGLKGGEGPQGPPGPVGSPGERGSA---GTAGPIGLPGRPGPQGPPGPAGEKGA------ 1052 Query: 86 TFPGALVPGGVA--DAAAAYKAAKAGAGLGGVPGVGG-LGVSAAPSVPGAVVP--QPGAG 140 PG P G A D AG G PG G G P G+ + G Sbjct: 1053 --PGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPP 1110 Query: 141 VKPGKVPGVGLPGVYPGGVLPGARFP----------GVGVLPGVPTGAGVK--PKAPGVG 188 PG VG PG+ G PG R G PG P G++ P PG Sbjct: 1111 GPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEK 1170 Query: 189 GAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAG 248 G + +GP G P P P G P A G G P + G + G G G G AG G Sbjct: 1171 GENGDVGPMGPPGPPGPRGPQG-PNGAD---GPQGPPGSVGSVG-GVGEKGEPGEAGNPG 1225 Query: 249 YPTGTGVG--------------PQAAAAAAAKA-----AAKFGAGAAGV----------- 278 P GVG P AA AK K G G Sbjct: 1226 PPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPG 1285 Query: 279 ---LPGVGGA----GVPGVPGAIPGIGGIAGVGTP--------AAAAAAAAAAKAAKYGA 323 GVGG G PG PG PG G AG P AA A K AK A Sbjct: 1286 PAGQDGVGGDKGEDGDPGQPGP-PGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEA 1344 Query: 324 AAGLVPGGPG-FGP-GVVGVPGA----GVPGV----GVPGA----------GIPVVPGA- 362 A PG G GP G G PG G+PG G+PGA G P +PG Sbjct: 1345 GAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLK 1404 Query: 363 GIPGA-------AVPGVVSP--EAAAKAAAKAAKYGARPGV-GVGGIPTYG--VGAGGFP 410 G PG+ + G++ P E K PG G GGIP +G G P Sbjct: 1405 GDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPP 1464 Query: 411 GF--------GVGVGGIPGVAGVPGVGGVPGVGGVPGVGISP 444 G G G G G G+ G PG G PG I P Sbjct: 1465 GLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQP 1506 Score = 89.0 bits (219), Expect = 1e-17 Identities = 146/519 (28%), Positives = 177/519 (34%), Gaps = 95/519 (18%) Query: 182 PKAPGVGGAFAGIPGV-GPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGK---LPYGYGP 237 P P G PG+ GP G P G P + P LPG GLP G LP+ YG Sbjct: 404 PPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGR-PGLPGADGLPGPPGTMLMLPFRYGG 462 Query: 238 GGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGI 297 G G PT + Q A A A A+ + G PG + Sbjct: 463 DGSKG-------PT---ISAQEAQAQAILQQARIA--------------LRGPPGPMGLT 498 Query: 298 GGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIP 357 G VG P ++ A + G P GP PG G PGA G G+P Sbjct: 499 GRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGAD------GGRGMP 552 Query: 358 VVPGA----GIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFG 413 PGA G G +PG+ + G G+ G +G G PG Sbjct: 553 GEPGAKGDRGFDG--LPGLPGDKGHRGERGPQGPPGPPGDDGMRG-EDGEIGPRGLPG-E 608 Query: 414 VGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKA 473 G G+ G G PG G PG+ GV G K G P Sbjct: 609 AGPRGLLGPRGTPGAPGQPGMAGVDG---------PPGPKGNMGPQGEPGP--------- 650 Query: 474 AQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAA 533 PG PG PG G G PG+ PG PG PG + Sbjct: 651 ------PGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPG-HPGKEGQSG 703 Query: 534 KSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPG-LGV-GA-GVPGLGVGAGVPGFGAVPG 590 + A G PG +G PG GV GA GV GL G G PG Sbjct: 704 EKGA---------------LGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPG 748 Query: 591 ALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAA 650 K + G G +G +G G G G A + +A + G +G Sbjct: 749 -------FKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVP 801 Query: 651 GLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPG 689 GL G G G G G G P A K A+ GVA +PG Sbjct: 802 GLPGY-PGRQGPKGSTGFPGFPGANGEKGAR-GVAGKPG 838 Score = 64.3 bits (155), Expect = 4e-10 Identities = 92/316 (29%), Positives = 108/316 (34%), Gaps = 24/316 (7%) Query: 392 PGVGVGGIPTYGVGAG--GFPGFG--VGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQ 447 PG+ V G P AG G PG G G PG G PG G+PG G+PG P Sbjct: 397 PGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPG---PPGTM 453 Query: 448 AAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVG 507 + G P +A +A A+A + PG G+ PG PG Sbjct: 454 LMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPG---PMGLTGRPGPVGGPGSS 510 Query: 508 VAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGL 567 A G PG GP GV K + R A G G+PG G G Sbjct: 511 GAKGESGDPGPQ-----GPRGVQGPPGPTGKPGKRG--RPGADGGRGMPGEPGAKGDRGF 563 Query: 568 GVGAGVPGLGVGAGVPGFGAVPG-----ALAAAKAAKYGAAVPGVLGGLGALGGVGIPGG 622 G+PG G G PG + +PG G G LG G PG Sbjct: 564 DGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGA 623 Query: 623 VVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKY 682 G A G G G G G G+PG G G PP K Sbjct: 624 PGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQG-NPGPQGLPGPQGPIG-PPGEKGPQGKP 681 Query: 683 GVAARPGFGLSPIFPG 698 G+A PG P PG Sbjct: 682 GLAGLPGADGPPGHPG 697 >gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo sapiens] Length = 1806 Score = 141 bits (356), Expect = 2e-33 Identities = 224/762 (29%), Positives = 264/762 (34%), Gaps = 139/762 (18%) Query: 25 RPG--GVPGAIPG-GVPGGVFYPGA-------GLGALGG-----GALGPGGKPLKPVPGG 69 +PG G PGA G G+PG PGA GL L G G GP G P P G Sbjct: 575 KPGKRGRPGADGGRGMPGE---PGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDG 631 Query: 70 LAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGL-GVSAAPS 128 + G G P P L+ G G PG G+ GV P Sbjct: 632 MRGEDGEIGPRGLPGEAGPRGLL---------------GPRGTPGAPGQPGMAGVDGPPG 676 Query: 129 VPGAVVPQ--PGAGVKPGKVPGVGLPGVYPGGVL--PGARFP-GVGVLPGVPTGAGVKPK 183 G + PQ PG + G GLPG P G + PG + P G L G+P GA P Sbjct: 677 PKGNMGPQGEPGPPGQQGNPGPQGLPG--PQGPIGPPGEKGPQGKPGLAGLP-GADGPPG 733 Query: 184 APGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPK----LPGGYGLPYTTGK-----LPYG 234 PG G +GP P P P+GYP P+ G GL + G+ P Sbjct: 734 HPGKEGQSGEKGALGP---PGPQGPIGYP--GPRGVKGADGVRGLKGSKGEKGEDGFPGF 788 Query: 235 YGPGGVAGAAGKAGY--PTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG 292 G G+ G G+ G P G GP+ A +G AG +G G+PG PG Sbjct: 789 KGDMGLKGDRGEVGQIGPRGED-GPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPG 847 Query: 293 AIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGP-------------------- 332 G G P A A A K G P GP Sbjct: 848 RQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSG 907 Query: 333 GFGP-------------GVVGVPGAGVPGVGVPGA-GIPVVPG----AGIPGAAVP---- 370 G GP G VG PG P G PG G+P PG G G P Sbjct: 908 GDGPPGPPGERGPQGPQGPVGFPGPKGP-PGPPGKDGLPGHPGQRGETGFQGKTGPPGPG 966 Query: 371 GVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFG--VGVGGIPGVAGVPGV 428 GVV P+ + G R G G P G G PG G G PG G+ G Sbjct: 967 GVVGPQG---PTGETGPIGERGHPGPPGPP----GEQGLPGAAGKEGAKGDPGPQGISGK 1019 Query: 429 GGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGV 488 G G+ G PG P AQ A K + G P + +A G+ PG Sbjct: 1020 DGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGP 1079 Query: 489 GVAPGVGVAPGVGLAPG----VGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQ 544 PG G APG G A GV VG+ GP G ++ Q Sbjct: 1080 QGPPGPAGEKG---APGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQ 1136 Query: 545 LRAAAGLG----AGIPGLGVGVGVPGLGVGAGVPG----LGV-----GAGVPGFGAVPGA 591 + G G PGL VG PG+ G G PG G+ G GF PG Sbjct: 1137 KGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGP 1196 Query: 592 LAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAG 651 + PG G G +G +G PG GP A G VG G Sbjct: 1197 IGLQGL----PGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVG 1252 Query: 652 LGGL--GVGGLGVPGVGGLGGIPPAAAAK--AAKYGVAARPG 689 G G G PG G+GG K A G A PG Sbjct: 1253 EKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPG 1294 Score = 136 bits (342), Expect = 8e-32 Identities = 245/857 (28%), Positives = 280/857 (32%), Gaps = 228/857 (26%) Query: 23 PSRPGGVPGAI-PGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGA 81 P P G PG P G PG PGA GP G P K G GA LG G Sbjct: 704 PQGPIGPPGEKGPQGKPGLAGLPGAD---------GPPGHPGKEGQSGEKGA-LGPP-GP 752 Query: 82 FPAVTFPGALVPGGV--ADAAAAYKAAKAGAGLGGVPGV-GGLGVSAAPSVPGAVVPQ-- 136 + +PG P GV AD K +K G G PG G +G+ G + P+ Sbjct: 753 QGPIGYPG---PRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGE 809 Query: 137 ---------------PGAGVKPGKVPGVGLPGV--YPG--GVLPGARFPGVGVLPGVPTG 177 PG + G+ +G+PG+ YPG G FPG G Sbjct: 810 DGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGA 869 Query: 178 AGVKPKA-----------------------PGVGGAFAGIPGVGPFG--GPQ-PGVPLGY 211 GV K PG G G GP G GPQ P P+G+ Sbjct: 870 RGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGF 929 Query: 212 PIKA--PKLPGGYGLPYTTGKL-------------PYGY----GPGGVAGAAGKAGYPTG 252 P P PG GLP G+ P G GP G G G+ G+P Sbjct: 930 PGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGP 989 Query: 253 TGV-GPQAAAAAAAKAAAKFGAGAAGV-----------------LPGV-------GGAGV 287 G G Q AA K AK G G+ LPG GG G Sbjct: 990 PGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGP 1049 Query: 288 PGVPGAI--PGIGGIAG----VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGV--- 338 G PG + PG G AG +G P A + GA P GP GV Sbjct: 1050 QGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP 1109 Query: 339 VGVPG----AGVPG-------VGVPGA----------GIPVVPG----AGIPG-AAVPGV 372 VG+PG AG PG +G PG G P PG G PG A G Sbjct: 1110 VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGE 1169 Query: 373 VSPEAAAKAAAKAAKYGAR-----PG-VGVGGIP--------TYGVGAGGFPG------- 411 P + GAR PG +G+ G+P VG G PG Sbjct: 1170 PGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGP 1229 Query: 412 -------------------FGVGVGGIPGVAGVPGVGGVPGVGGVPGV-GISPEA--QAA 449 GVG G PG AG PG G GVGG G G EA A Sbjct: 1230 QGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGA 1289 Query: 450 AAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVA 509 A AK G P K F PG PG GVG G PG Sbjct: 1290 AGPPGAK---GPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGP 1346 Query: 510 PGVGVAPGVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRAAAGLGA--------------- 553 PG G PG GP G A A + AK + A G Sbjct: 1347 PGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGP 1406 Query: 554 ----GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALA--------------AA 595 GIPG G+PG G PG G+PG PG+ Sbjct: 1407 EGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGE 1466 Query: 596 KAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL 655 + K +PG G GA G GIPG GP G G AG Sbjct: 1467 QGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAG---- 1522 Query: 656 GVGGLGVPGVGGLGGIP 672 G G+PG G G P Sbjct: 1523 QKGDSGLPGPPGSPGPP 1539 Score = 132 bits (332), Expect = 1e-30 Identities = 199/656 (30%), Positives = 226/656 (34%), Gaps = 88/656 (13%) Query: 22 HPSRPG--GVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGL 79 HP + G G G PGGV P G G +G G P P P G GL Sbjct: 947 HPGQRGETGFQGKTGPPGPGGVVGPQGPTGETG--PIGERGHPGPPGPPG--EQGLPGAA 1002 Query: 80 GAFPAVTFPGALVPGGVA--DAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVVPQP 137 G A PG P G++ D A + GL G G GL P P V P Sbjct: 1003 GKEGAKGDPG---PQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSP 1059 Query: 138 GAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGV 197 G G +GLPG PG + P PG P G P G G AG GV Sbjct: 1060 GERGSAGTAGPIGLPG------RPGPQGP-----PG-PAGEKGAPGEKGPQGP-AGRDGV 1106 Query: 198 -GPFGGPQPGVPLGYP--------IKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAG 248 GP G P P P G P I P G G G GP G+ G G G Sbjct: 1107 QGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPP----GPPGLQGPVGAPG 1162 Query: 249 YPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPA 307 G G GP+ + + G G +G G+PG PG G + +G P Sbjct: 1163 IAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPG 1222 Query: 308 AAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPG-AGIPVVPG-AGIP 365 G P GP PG VG G GV G PG AG P PG AG+ Sbjct: 1223 PPGPRGPQGPNGADG------PQGP---PGSVGSVG-GVGEKGEPGEAGNPGPPGEAGVG 1272 Query: 366 GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGV 425 G G + A A GA+ G G P G GFPG G G PG AG Sbjct: 1273 GPK--GERGEKGEAGPPGAAGPPGAKGPPGDDG-PKGNPGPVGFPG-DPGPPGEPGPAGQ 1328 Query: 426 PGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAA------KAAAKAAQFGLV 479 GVGG G G PG P A G P AA A K A A Sbjct: 1329 DGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGP 1388 Query: 480 PGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG-IGPGGVAAAAKSAAK 538 PG G G G+ PG G+ A G PG +GP G+ Sbjct: 1389 PGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGS 1448 Query: 539 VAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAA 598 K G PGL +G PG G GL G PG A Sbjct: 1449 KGEK-----------GHPGLIGLIGPPGEQGEKGDRGLPGTQGSPG-------------A 1484 Query: 599 KYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGG 654 K +PG G LG G G+PG GP + A + GL G G G Sbjct: 1485 KGDGGIPGPAGPLGPPGPPGLPG---PQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1537 Score = 110 bits (274), Expect = 6e-24 Identities = 205/729 (28%), Positives = 249/729 (34%), Gaps = 131/729 (17%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAF 82 P+ P G+ G P G+ G PG G GP G+P P GL G G Sbjct: 446 PAGPAGIMG--PPGLQGPTGPPG------DPGDRGPPGRPGLPGADGLPGP---PGTMLM 494 Query: 83 PAVTFPGALVPGGVADAAAAYKAA---KAGAGLGGVPGVGGLGVSAAPSVPGAVVPQPGA 139 + G G A A A +A L G PG GL Sbjct: 495 LPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTG---------------- 538 Query: 140 GVKPGKVPGVGLPGVYPGGVLPGARFP-GVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVG 198 +PG V G G G PG + P GV PG PTG K PG G G+PG Sbjct: 539 --RPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPG-PTGKPGKRGRPGADGG-RGMPGEP 594 Query: 199 PFGGPQ-----PGVP--LGY-----PIKAPKLPGGYGLPYTTGK-----LPYGYGPGGVA 241 G + PG+P G+ P P PG G+ G+ LP GP G+ Sbjct: 595 GAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLL 654 Query: 242 GAAGKAGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAI--PGIG 298 G G G P G+ G + G G G G+PG G I PG Sbjct: 655 GPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEK 714 Query: 299 GIAG----VGTPAAAAAAAAAAKAAKYGAAAGLVPGGP----GFGPGVVGVPGA-GVPGV 349 G G G P A K + G L P GP G+ PG GV GA GV G+ Sbjct: 715 GPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGY-PGPRGVKGADGVRGL 773 Query: 350 ----------GVPG--AGIPVVPGAGIPGAAVP-GVVSPEAAAKAA------AKAAKYGA 390 G PG + + G G P G PE A + + G Sbjct: 774 KGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGE 833 Query: 391 RPGVGVGGIPTY-----GVGAGGFPGF--GVGVGGIPGVAGVPGVGGVPGVGGVPGVGIS 443 + +GV G+P Y G+ GFPGF G G GVAG PG G G G G + Sbjct: 834 KGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGA 893 Query: 444 PEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPG---- 499 K G G P + PG PG G+ PG Sbjct: 894 RGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGE 953 Query: 500 VGL-----APGVGVAPG----VGVAPGVGVAPGIGPGG-------VAAAAKSAAKVAAKA 543 G PG G G G +G GP G AA K AK Sbjct: 954 TGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGP 1013 Query: 544 QLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAA 603 Q + AG+ G G+PG G PGL G G G PG + + Sbjct: 1014 QGISGKDGPAGLRGFPGERGLPG---AQGAPGLKGGEGPQG---PPGPVGS--------- 1058 Query: 604 VPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVP 663 PG G G G +G+PG GP A A + G G G+ G +G+P Sbjct: 1059 -PGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGV----QGPVGLP 1113 Query: 664 GVGGLGGIP 672 G G G P Sbjct: 1114 GPAGPAGSP 1122 Score = 92.0 bits (227), Expect = 2e-18 Identities = 162/522 (31%), Positives = 181/522 (34%), Gaps = 120/522 (22%) Query: 26 PGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAV 85 PG G P G PG V PG A G GP G P +P P G G G Sbjct: 1041 PGLKGGEGPQGPPGPVGSPGERGSA---GTAGPIGLPGRPGPQGPPGPAGEKGA------ 1091 Query: 86 TFPGALVPGGVA--DAAAAYKAAKAGAGLGGVPGVGG-LGVSAAPSVPGAVVP--QPGAG 140 PG P G A D AG G PG G G P G+ + G Sbjct: 1092 --PGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPP 1149 Query: 141 VKPGKVPGVGLPGVYPGGVLPGARFP----------GVGVLPGVPTGAGVK--PKAPGVG 188 PG VG PG+ G PG R G PG P G++ P PG Sbjct: 1150 GPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEK 1209 Query: 189 GAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAG 248 G + +GP G P P P G P A G G P + G + G G G G AG G Sbjct: 1210 GENGDVGPMGPPGPPGPRGPQG-PNGAD---GPQGPPGSVGSVG-GVGEKGEPGEAGNPG 1264 Query: 249 YPTGTGVG--------------PQAAAAAAAKA-----AAKFGAGAAGV----------- 278 P GVG P AA AK K G G Sbjct: 1265 PPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPG 1324 Query: 279 ---LPGVGGA----GVPGVPGAIPGIGGIAGVGTP--------AAAAAAAAAAKAAKYGA 323 GVGG G PG PG PG G AG P AA A K AK A Sbjct: 1325 PAGQDGVGGDKGEDGDPGQPGP-PGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEA 1383 Query: 324 AAGLVPGGPG-FGP-GVVGVPGA----GVPGV----GVPGA----------GIPVVPGA- 362 A PG G GP G G PG G+PG G+PGA G P +PG Sbjct: 1384 GAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLK 1443 Query: 363 GIPGA-------AVPGVVSP--EAAAKAAAKAAKYGARPGV-GVGGIPTYG--VGAGGFP 410 G PG+ + G++ P E K PG G GGIP +G G P Sbjct: 1444 GDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPP 1503 Query: 411 GF--------GVGVGGIPGVAGVPGVGGVPGVGGVPGVGISP 444 G G G G G G+ G PG G PG I P Sbjct: 1504 GLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQP 1545 Score = 89.0 bits (219), Expect = 1e-17 Identities = 146/519 (28%), Positives = 177/519 (34%), Gaps = 95/519 (18%) Query: 182 PKAPGVGGAFAGIPGV-GPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGK---LPYGYGP 237 P P G PG+ GP G P G P + P LPG GLP G LP+ YG Sbjct: 443 PPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGR-PGLPGADGLPGPPGTMLMLPFRYGG 501 Query: 238 GGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGI 297 G G PT + Q A A A A+ + G PG + Sbjct: 502 DGSKG-------PT---ISAQEAQAQAILQQARIA--------------LRGPPGPMGLT 537 Query: 298 GGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIP 357 G VG P ++ A + G P GP PG G PGA G G+P Sbjct: 538 GRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGAD------GGRGMP 591 Query: 358 VVPGA----GIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFG 413 PGA G G +PG+ + G G+ G +G G PG Sbjct: 592 GEPGAKGDRGFDG--LPGLPGDKGHRGERGPQGPPGPPGDDGMRG-EDGEIGPRGLPG-E 647 Query: 414 VGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKA 473 G G+ G G PG G PG+ GV G K G P Sbjct: 648 AGPRGLLGPRGTPGAPGQPGMAGVDG---------PPGPKGNMGPQGEPGP--------- 689 Query: 474 AQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAA 533 PG PG PG G G PG+ PG PG PG + Sbjct: 690 ------PGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPG-HPGKEGQSG 742 Query: 534 KSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPG-LGV-GA-GVPGLGVGAGVPGFGAVPG 590 + A G PG +G PG GV GA GV GL G G PG Sbjct: 743 EKGA---------------LGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPG 787 Query: 591 ALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAA 650 K + G G +G +G G G G A + +A + G +G Sbjct: 788 -------FKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVP 840 Query: 651 GLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPG 689 GL G G G G G G P A K A+ GVA +PG Sbjct: 841 GLPGY-PGRQGPKGSTGFPGFPGANGEKGAR-GVAGKPG 877 Score = 64.3 bits (155), Expect = 4e-10 Identities = 92/316 (29%), Positives = 108/316 (34%), Gaps = 24/316 (7%) Query: 392 PGVGVGGIPTYGVGAG--GFPGFG--VGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQ 447 PG+ V G P AG G PG G G PG G PG G+PG G+PG P Sbjct: 436 PGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPG---PPGTM 492 Query: 448 AAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVG 507 + G P +A +A A+A + PG G+ PG PG Sbjct: 493 LMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPG---PMGLTGRPGPVGGPGSS 549 Query: 508 VAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGL 567 A G PG GP GV K + R A G G+PG G G Sbjct: 550 GAKGESGDPGPQ-----GPRGVQGPPGPTGKPGKRG--RPGADGGRGMPGEPGAKGDRGF 602 Query: 568 GVGAGVPGLGVGAGVPGFGAVPG-----ALAAAKAAKYGAAVPGVLGGLGALGGVGIPGG 622 G+PG G G PG + +PG G G LG G PG Sbjct: 603 DGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGA 662 Query: 623 VVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKY 682 G A G G G G G G+PG G G PP K Sbjct: 663 PGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQG-NPGPQGLPGPQGPIG-PPGEKGPQGKP 720 Query: 683 GVAARPGFGLSPIFPG 698 G+A PG P PG Sbjct: 721 GLAGLPGADGPPGHPG 736 >gi|18105032 type X collagen alpha 1 precursor [Homo sapiens] Length = 680 Score = 141 bits (356), Expect = 2e-33 Identities = 168/559 (30%), Positives = 201/559 (35%), Gaps = 72/559 (12%) Query: 117 GVGGLGVSAAPSVPGAVVPQ--PGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGV 174 G+ G P PG P+ PG PGK PG PG+ PG+ Sbjct: 52 GIAVRGEQGTPGPPGPAGPRGHPGPSGPPGK---------------PGYGSPGLQGEPGL 96 Query: 175 PTGAGVKPKAPGVGGAFAGIPGV----GPFGGPQPGVPLGYPIKAPK-LPGGYGLPYTTG 229 P G P A G G G+PG GP+G P G P P+ PG G+P G Sbjct: 97 PGPPG--PSAVGKPGV-PGLPGKPGERGPYGPKGDVGPAGLP--GPRGPPGPPGIPGPAG 151 Query: 230 -KLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVP 288 +P G G GA G G+P G P K +GA G+ G P Sbjct: 152 ISVPGKPGQQGPTGAPGPRGFPGEKG-APGVPGMNGQKGEMGYGAPGRPGERGLPGPQGP 210 Query: 289 GVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPG 348 P PG+G G P + G + P GP PG G G G PG Sbjct: 211 TGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGP---IGPPGPQGPPGERGPEGIGKPG 267 Query: 349 -VGVPGAGIPVVPGA-GIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGA 406 G PG P +PG G+PGA PG+ P PG G G+P Sbjct: 268 AAGAPGQ--PGIPGTKGLPGA--PGIAGPPGP-------------PGFGKPGLP------ 304 Query: 407 GGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAA 466 G G G G+PG G G G G+ G PG+ P K G P Sbjct: 305 -GLKG-ERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKG 362 Query: 467 AKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI-G 525 A A + G +PG PG PG+ G PG PGVG PG+ G Sbjct: 363 ETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPG 422 Query: 526 PGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGF 585 P G A AK +A R A GIPG +G P G+PG G PG Sbjct: 423 PVG-PAGAKGMPGHNGEAGPRGA----PGIPGTRGPIGPP------GIPGFPGSKGDPGS 471 Query: 586 GAVPG-ALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQF 644 PG A A K PG G G G G+PG GP A + KA Q Sbjct: 472 PGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQR 531 Query: 645 GLVGAAGLGGLGVGGLGVP 663 + L G G+P Sbjct: 532 PSLSGTPLVSANQGVTGMP 550 Score = 126 bits (316), Expect = 8e-29 Identities = 181/568 (31%), Positives = 217/568 (38%), Gaps = 101/568 (17%) Query: 28 GVPG-AIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVT 86 G PG A P G PG P G G G+ G G+P P P G + G G+ P Sbjct: 63 GPPGPAGPRGHPG----PSGPPGKPGYGSPGLQGEPGLPGPPGPSAVG-KPGVPGLPGK- 116 Query: 87 FPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPG-AVVPQPGAGVKPGK 145 PG P G K G G+P G G P +PG A + PG KPG+ Sbjct: 117 -PGERGPYG----------PKGDVGPAGLP--GPRGPPGPPGIPGPAGISVPG---KPGQ 160 Query: 146 VPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPK----APGVGGAFAGIPGVGPFG 201 G PG P G FPG PGVP G K + APG G G+P GP G Sbjct: 161 QGPTGAPG--PRG------FPGEKGAPGVPGMNGQKGEMGYGAPGRPGE-RGLP--GPQG 209 Query: 202 GPQPGVPLGYPIKAPK-LPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAA 260 P P G + +PG G+ G P GP G G G G G+G A Sbjct: 210 PTGPSGPPGVGKRGENGVPGQPGIKGDRG-FPGEMGPIGPPGPQGPPGERGPEGIGKPGA 268 Query: 261 AAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG-AIPGIGGIAGVGTPAAAAAAAAAAKAA 319 A A + G G PG+ AG PG PG PG+ G+ G PA Sbjct: 269 AGAPGQPGIPGTKGLPGA-PGI--AGPPGPPGFGKPGLPGLKGERGPAG----------- 314 Query: 320 KYGAAAGLVPGGPGF--GPGVVGVPGAGVPGV-GVPGAGIPVVPGAGIPGA-AVPGVVSP 375 +PGGPG G G+PG PG+ G PG P P GIPG+ +PG Sbjct: 315 --------LPGGPGAKGEQGPAGLPGK--PGLTGPPGNMGPQGP-KGIPGSHGLPGPKGE 363 Query: 376 EAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVG 435 A A G R G G P G+PG G+ G G G+PG G PGVG Sbjct: 364 TGPAGPAGYPGAKGERGSPGSDGKP-------GYPG-KPGLDGPKGNPGLPGPKGDPGVG 415 Query: 436 GVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVG 495 G PG+ P A A G P A + G PG+ PG PG Sbjct: 416 GPPGLP-GPVGPAGAKGMPGHNGEAGPRGAPGIPGTR-GPIG-PPGIPGFPGSKGDPGSP 472 Query: 496 VAPG-VGLA----------PGVGVAPGVGVAPGVGVAPG-IGPGGVAAAAKSAAKVAAKA 543 PG G+A PG G PG+ PG GP G A + K + Sbjct: 473 GPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRP 532 Query: 544 QLRAAAGLGAGIPGLGVGVGVPGLGVGA 571 L +G P + GV G+ V A Sbjct: 533 SL-------SGTPLVSANQGVTGMPVSA 553 Score = 122 bits (306), Expect = 1e-27 Identities = 167/503 (33%), Positives = 196/503 (38%), Gaps = 86/503 (17%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGL-------GALGGGALG-PG--GKPLKPVPGGLAG 72 P+ P G PG P G PG Y GL G G A+G PG G P KP G G Sbjct: 67 PAGPRGHPG--PSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYG 124 Query: 73 AGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGA-GLGGVPGVGGL-GVSAAPSVP 130 G P P P G+ A K G G G PG G G AP VP Sbjct: 125 PKGDVGPAGLPGPRGPPG--PPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVP 182 Query: 131 GAVVPQPGAGV-KPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGG 189 G + G PG+ GLPG P G + PGVG G P PG+ G Sbjct: 183 GMNGQKGEMGYGAPGRPGERGLPG--PQGPTGPSGPPGVG-----KRGENGVPGQPGIKG 235 Query: 190 AFAGIPG-VGPFGGPQPGVP--------LGYPIKA-----PKLPGGYGLPYTTGKL---- 231 G PG +GP G P P P +G P A P +PG GLP G Sbjct: 236 D-RGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPG 294 Query: 232 PYGYG-PG--GVAGAAGKAGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGV 287 P G+G PG G+ G G AG P G G G Q A K G G +G G Sbjct: 295 PPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKP------GLTGPPGNMGPQGP 348 Query: 288 PGVPGA--IPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGF-GP-GVVGVPG 343 G+PG+ +PG G G PA A + G PG PG GP G G+PG Sbjct: 349 KGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGY-PGKPGLDGPKGNPGLPG 407 Query: 344 A-GVPGVG----VPG----AGIPVVPG----------AGIPGAAVPGVVSPEAAAKAAAK 384 G PGVG +PG AG +PG GIPG P + P Sbjct: 408 PKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGP--IGPPGIPGFPGS 465 Query: 385 AAKYGARPGVGVGGIPTYGV-GAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGIS 443 G+ G GI T G+ G G PG G G +G PG+ G PG G PG + Sbjct: 466 KGDPGSPGPPGPAGIATKGLNGPTGPPG----PPGPRGHSGEPGLPGPPGPPGPPGQAVM 521 Query: 444 PEAQAAAAAKAAKYGVGTPAAAA 466 PE A + + GTP +A Sbjct: 522 PEGFIKAGQRPSL--SGTPLVSA 542 Score = 117 bits (293), Expect = 4e-26 Identities = 145/460 (31%), Positives = 176/460 (38%), Gaps = 48/460 (10%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAF 82 P P G PG IPG P G+ PG GA GP G P + G+ G G + Sbjct: 137 PRGPPGPPG-IPG--PAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGY 193 Query: 83 PAVTFPGAL-VPGGVADAAAAYKAAKAGAGLGGVPGVGGL-GVSAAPSVPGAVVPQPGAG 140 A PG +PG + G GVPG G+ G P G + P PG Sbjct: 194 GAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGP-PGPQ 252 Query: 141 VKPGK--VPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVG 198 PG+ G+G PG PG PG LPG P AG P PG G G+PG+ Sbjct: 253 GPPGERGPEGIGKPGAAGAPGQPG--IPGTKGLPGAPGIAG-PPGPPGFGKP--GLPGLK 307 Query: 199 PFGGPQPGVPLGYPIKAPKLPGGY-GLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGP 257 GP G+P G K + P G G P TG P GP G G G G P G Sbjct: 308 GERGPA-GLPGGPGAKGEQGPAGLPGKPGLTGP-PGNMGPQGPKGIPGSHGLPGPKGETG 365 Query: 258 QAAAAAAAKAAAKFGAGAAGVLPGVGGA-------GVPGVPG--AIPGIGGIAGVGTPAA 308 A A A + G+ + PG G G PG+PG PG+GG G+ P Sbjct: 366 PAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVG 425 Query: 309 AAAAAAAAKAAKYGAAAGLVPGGPG-FGP-GVVGVPGAGVPGVGVPGAGIPVVPGA---- 362 A A +PG G GP G G+PG P +G PG IP PG+ Sbjct: 426 PAGAKG-------------MPGHNGEAGPRGAPGIPGTRGP-IGPPG--IPGFPGSKGDP 469 Query: 363 GIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGV 422 G PG P ++ + G R G G+P G G PG V G Sbjct: 470 GSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPG-PPGPPGPPGQAVMPEGFIKA 528 Query: 423 AGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTP 462 P + G P V GV P + A +GTP Sbjct: 529 GQRPSLSGTPLVSANQGVTGMPVSAFTVILSKAYPAIGTP 568 Score = 108 bits (271), Expect = 1e-23 Identities = 148/499 (29%), Positives = 178/499 (35%), Gaps = 101/499 (20%) Query: 198 GPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGY----GPGGVAGAAGKAGYPTGT 253 G F + +P G P + +PYT G G G AG G+P Sbjct: 18 GVFYAERYQMPTGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPGPAGPRGHP--- 74 Query: 254 GVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAA 313 GP +G G PG G G+ G PG +PG G + VG P Sbjct: 75 --GP---------------SGPPGK-PGYGSPGLQGEPG-LPGPPGPSAVGKPGVPGLPG 115 Query: 314 AAAKAAKYGAAAGLVPGG---PGFGPGVVGVPG-AGVPGVGVPGAGIPV-VPGA-GIPGA 367 + YG + P G P PG G+PG AG+ G PG P PG G PG Sbjct: 116 KPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGE 175 Query: 368 -AVPGVVSPEAAAKAAAKAAKYGA--RPGV-GVGGIPTYGVGAGGFPGFGV-GVGGIPGV 422 PGV YGA RPG G+ G P G G PG G G G+PG Sbjct: 176 KGAPGVPGMNGQKGEMG----YGAPGRPGERGLPG-PQGPTGPSGPPGVGKRGENGVPGQ 230 Query: 423 AGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGV 482 G+ G G PG G I P + G+G P AA A PG+ Sbjct: 231 PGIKGDRGFPGEMGP----IGPPGPQGPPGERGPEGIGKPGAAGAPGQ---------PGI 277 Query: 483 GVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAK 542 G+ APG+ PG PG G PG+ G G+ PGG A + Sbjct: 278 PGTKGLPGAPGIAGPPG---PPGFG-KPGLPGLKGERGPAGL-PGGPGAKGEQGP----- 327 Query: 543 AQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGA 602 AG+PG PGL G G G+PG +PG A A Sbjct: 328 ----------AGLPGK------PGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAG-PA 370 Query: 603 AVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGV 662 PG G G+ G G PG + GL G G GL G G Sbjct: 371 GYPGAKGERGSPGSDGKPG------------------YPGKPGLDGPKGNPGLP-GPKGD 411 Query: 663 PGVGGLGGIPPAAAAKAAK 681 PGVGG G+P AK Sbjct: 412 PGVGGPPGLPGPVGPAGAK 430 Score = 48.5 bits (114), Expect = 2e-05 Identities = 66/226 (29%), Positives = 77/226 (34%), Gaps = 45/226 (19%) Query: 479 VPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI-GPGGVAAAAKSAA 537 V G PG G PG PG PG G +PG+ PG+ GP G +A K Sbjct: 55 VRGEQGTPGPPGPAGPRGHPGPSGPPG---KPGYG-SPGLQGEPGLPGPPGPSAVGKPGV 110 Query: 538 KVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKA 597 G+PG G G G GL G PG +PG + Sbjct: 111 P---------------GLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVP 155 Query: 598 AKYGAAVPGVLGGLGALGGVGIPG-----GVVGAGPAAAAAAAKAAAKAAQFGLVGAAGL 652 K PG G GA G G PG GV G A + + GL G G Sbjct: 156 GK-----PGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQG- 209 Query: 653 GGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPG 698 G G PGVG K + GV +PG FPG Sbjct: 210 ---PTGPSGPPGVG-----------KRGENGVPGQPGIKGDRGFPG 241 >gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens] Length = 703 Score = 140 bits (353), Expect = 4e-33 Identities = 205/665 (30%), Positives = 243/665 (36%), Gaps = 126/665 (18%) Query: 52 GGGALGPGG----KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAK 107 GGGA G G K ++P+ G G G G + + P L+P Sbjct: 29 GGGAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLP--LLP-------------- 72 Query: 108 AGAGLGGVPGVGGLGVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVY----PGGVLPGA 163 L G PG P PG P PG PGK PG+G PG++ P G PG Sbjct: 73 --MDLKGEPG--------PPGKPGPRGP-PGPPGFPGK-PGMGKPGLHGQPGPAGP-PGF 119 Query: 164 RFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQ--PGVPLGYPIKAPKLPGG 221 G PG+P G P PG+ G GI G GP PG+P I P PG Sbjct: 120 SRMGKAGPPGLPGKVG-PPGQPGLRGE-PGIRGDQGLRGPPGPPGLPGPSGITIPGKPGA 177 Query: 222 YGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPG 281 G+P GP G G G G P GP G G G LPG Sbjct: 178 QGVP----------GPPGFQGEPGPQGEP-----GPPGDRGLKGDN----GVGQPG-LPG 217 Query: 282 VGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGV 341 G G G PG PG+ G AG+G P A + G VPG G PG VG Sbjct: 218 APGQG--GAPGP-PGLPGPAGLGKPGLDGLPGAPGDKGESGPPG--VPGPRG-EPGAVGP 271 Query: 342 PGA-GVPGVGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIP 400 G GV GVGVPGA AG+PG P E + G G+ G+P Sbjct: 272 KGPPGVDGVGVPGA-------AGLPGPQGPSGAKGEPGTRGPPGLI---GPTGYGMPGLP 321 Query: 401 --TYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYG 458 G G PG +G G PG G PG G G+GG PG+ +A + G Sbjct: 322 GPKGDRGPAGVPGL-LGDRGEPGEDGEPGEQGPQGLGGPPGL-------PGSAGLPGRRG 373 Query: 459 VGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGV 518 P A G G PGV G G+ PGV PG PG Sbjct: 374 PPGPKGEA--------------GPGGPPGVPGIRGDQGPSGLAGKPGV---PGERGLPGA 416 Query: 519 GVAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLGA-GIPGLGVGVGVPGLGVGAGVPGL 576 PG GP G L LG G PGL G+PGL AG G Sbjct: 417 HGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGP 476 Query: 577 GVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPG--GVVG-AGPAAAAA 633 G+ G +PG +A + G A G G G+PG G+ G GP Sbjct: 477 QGLPGLKGEPGLPGPPGEGRAGEPGTA--------GPTGPPGVPGSPGITGPPGPPGPPG 528 Query: 634 AAKAAAKAAQFGLVGAAGLGGLGVGGLGVPG-VGGLGGIPPAAAAKAAKYGVAARPGFGL 692 A G G+ GL + GV G V G GG P + + + A Sbjct: 529 PPGAP------GAFDETGIAGLHLPNGGVEGAVLGKGGKPQFGLGELSAHATPAFTAVLT 582 Query: 693 SPIFP 697 SP FP Sbjct: 583 SP-FP 586 Score = 128 bits (322), Expect = 2e-29 Identities = 161/462 (34%), Positives = 180/462 (38%), Gaps = 80/462 (17%) Query: 26 PGGVPG------AIPGGVPGGVFYPGA-GLGALGG-----GALGPGGKPLKPVPGGLAGA 73 P G PG A P G+PG V PG GL G G GP G P P P G+ Sbjct: 113 PAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIP 172 Query: 74 GLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAV 133 G G F G P G GL G GVG G+ AP GA Sbjct: 173 GKPGAQGVPGPPGFQGEPGPQGEP-------GPPGDRGLKGDNGVGQPGLPGAPGQGGA- 224 Query: 134 VPQPGAGVKPGKVPGVGLPGV--YPGGVLPGARFPGVGVLPGVPTGAG----VKPKAP-G 186 PG PG G+G PG+ PG PG + G PGVP G V PK P G Sbjct: 225 ---PGPPGLPGPA-GLGKPGLDGLPGA--PGDK--GESGPPGVPGPRGEPGAVGPKGPPG 276 Query: 187 VGGAFAGIPGVGPFGGPQ-PGVPLGYPIKA--PKL--PGGYGLPYTTGKLPYG-YGPGGV 240 V G G+PG GPQ P G P P L P GYG+P G P G GP GV Sbjct: 277 VDGV--GVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPG--PKGDRGPAGV 332 Query: 241 AGAAGKAGYPTGTGV----GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPG 296 G G G P G GPQ + G G PG G PG P +PG Sbjct: 333 PGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGP-PGPKGEAGPGGPPGVPG 391 Query: 297 IGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGA-- 354 I G G A + GA P GP PG G PG G GV GA Sbjct: 392 IRG--DQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPG----GPGVAGALG 445 Query: 355 -----GIPVVPG----AGIPGAAVP-GVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGV 404 G+P PG +GIPG P G + P+ G + G+ G P G Sbjct: 446 QKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLP---------GLKGEPGLPGPP--GE 494 Query: 405 GAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEA 446 G G PG G G PGV G PG+ G PG G PG +P A Sbjct: 495 GRAGEPGTA-GPTGPPGVPGSPGITGPPGPPGPPGPPGAPGA 535 Score = 107 bits (266), Expect = 5e-23 Identities = 169/576 (29%), Positives = 203/576 (35%), Gaps = 118/576 (20%) Query: 179 GVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGK-----LPY 233 G P+A GGA GG P+ Y P G G P+ GK +P Sbjct: 21 GCGPRASSGGGA----------GGAAGYAPVKYI--QPMQKGPVGPPFREGKGQYLEMPL 68 Query: 234 GYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGA 293 P + G G G P GP+ G G PG PG Sbjct: 69 PLLPMDLKGEPGPPGKP-----GPR------------------------GPPGPPGFPGK 99 Query: 294 IPGIG--GIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPG--GPGFGPGVVGVPGA-GVPG 348 PG+G G+ G PA + KA G +PG GP PG+ G PG G G Sbjct: 100 -PGMGKPGLHGQPGPAGPPGFSRMGKAGPPG-----LPGKVGPPGQPGLRGEPGIRGDQG 153 Query: 349 VGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGV-GVGGIPTYGVGAG 407 + P G P +PG G +PG + A+ + PG G G P G Sbjct: 154 LRGP-PGPPGLPGPS--GITIPG----KPGAQGVPGPPGFQGEPGPQGEPGPP----GDR 202 Query: 408 GFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPG-VGI-SPEAQAAAAAKAAKYGVGTPAAA 465 G G GVG PG+ G PG GG PG G+PG G+ P A K G P Sbjct: 203 GLKGDN-GVGQ-PGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVP 260 Query: 466 AAKAAAKAAQFGLVPGV-GV-APGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG 523 + A PGV GV PG PG G PG PG+ G G+ PG Sbjct: 261 GPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGM-PG 319 Query: 524 I-------GPGGVAAAAKSAAKVAAKAQ--LRAAAGLG--------AGIPGL-------- 558 + GP GV + + + GLG AG+PG Sbjct: 320 LPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKG 379 Query: 559 ----GVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALA----AAKAAKYG----AAVPG 606 G GVPG+ G GL GVPG +PGA + G PG Sbjct: 380 EAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPG 439 Query: 607 VLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL----GVGGLGV 662 V G LG G +G+PG GP+ A GL G G GL G G G Sbjct: 440 VAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGE 499 Query: 663 PGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPG 698 PG G G PP G PG P PG Sbjct: 500 PGTAGPTG-PPGVPGSPGITGPPGPPGPPGPPGAPG 534 Score = 98.6 bits (244), Expect = 2e-20 Identities = 145/466 (31%), Positives = 173/466 (37%), Gaps = 102/466 (21%) Query: 23 PSRPG--GVPGAIPG--GVPGGVFYPG--AGLGALGGGALGPGGKPLKPVPGGLAGA-GL 75 P +PG GVPG PG G PG PG G G +G G P P GG G GL Sbjct: 172 PGKPGAQGVPGP-PGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGL 230 Query: 76 G--AGLGAFPAVTFPGALVPGGVADAAAAYKAAKAG----AGLGGVPGVGGLGVSAAPSV 129 AGLG PGA PG ++ G G G PGV G+GV A + Sbjct: 231 PGPAGLGKPGLDGLPGA--PGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGL 288 Query: 130 PGAVVP-----QPGAGVKPGKV--PGVGLPGVYPG-----------GVLPGARFPGVGVL 171 PG P +PG PG + G G+PG+ PG G+L PG Sbjct: 289 PGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGL-PGPKGDRGPAGVPGLLGDRGEPGEDGE 347 Query: 172 PGV--PTGAGVKPKAPGVGGAFAGIPG----VGPFGGPQPGVPLGYP-IKAPKLPGGY-G 223 PG P G G P PG AG+PG GP G PG P G P I+ + P G G Sbjct: 348 PGEQGPQGLGGPPGLPGS----AGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAG 403 Query: 224 LPYTTGK--LPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGA-------- 273 P G+ LP +GP G G G+ G+ TG GP A A K Sbjct: 404 KPGVPGERGLPGAHGPPGPTGPKGEPGF-TGRPGGPGVAGALGQKGDLGLPGQPGLRGPS 462 Query: 274 ------GAAGVL-----------------PGVGGAGVPGVPG-----AIPGIGGIAGVGT 305 G AG + PG G AG PG G +PG GI G Sbjct: 463 GIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGPPG 522 Query: 306 PAAAAAAAAAAKAAKYGAAAGL-VPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGI 364 P A A AGL +P G GV GA + G P G+ + Sbjct: 523 PPGPPGPPGAPGAFDETGIAGLHLPNG--------GVEGAVLGKGGKPQFGLGELSAHAT 574 Query: 365 PGAAVPGVVSPEAAAKAAAKAAK------YGARPGVGVGGIPTYGV 404 P A + SP A+ K + G P G+ P GV Sbjct: 575 P-AFTAVLTSPFPASGMPVKFDRTLYNGHSGYNPATGIFTCPVGGV 619 >gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens] Length = 1604 Score = 139 bits (350), Expect = 9e-33 Identities = 218/730 (29%), Positives = 255/730 (34%), Gaps = 112/730 (15%) Query: 28 GVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKP-LKPVPG--GLAGA-GLGAGLGAFP 83 G+PGA PG G + PG G GP G P L+ VPG GL G GL A LG+ P Sbjct: 888 GMPGA-PGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLP 946 Query: 84 AVTFPGALVPGGVADAAAA---YKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVVPQPGAG 140 + G A Y K G G+PGV GL A + + +P A Sbjct: 947 IEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLS---LERPRAE 1003 Query: 141 VKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGV-GP 199 G G PG LPG PG+P G + G PG+ G Sbjct: 1004 EARGD-NSEGDPGCVGSPGLPGP--------PGLPGQRGEE-----------GPPGMRGS 1043 Query: 200 FGGPQPGVPLGYP--IKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGP 257 G P P P G+P + +P LPG G TG G G G G+ GYP TG P Sbjct: 1044 PGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLT----GDKGEPGPPGQPGYPGATG--P 1097 Query: 258 QAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAK 317 + AG G G G+PG PG G G + Sbjct: 1098 PGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQ 1157 Query: 318 AAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGV-----GVPG-AGIPVVPGAGIPGAAVPG 371 G PG PGF PG VG PG P G+ G +G+P PG P PG Sbjct: 1158 PGFPGP-----PGPPGF-PGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGP----PG 1207 Query: 372 VVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVG--GIPGVAGVPGVG 429 + P K K G R G G P G G PGF G G+PG G G Sbjct: 1208 IQGPAGLDGLDGKDGKPGLRGDPGPAGPP----GLMGPPGFKGKTGHPGLPGPKGDCGKP 1263 Query: 430 GVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVG 489 G PG G PG P A VG P A + GL G G Sbjct: 1264 GPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGERG 1323 Query: 490 VAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI-------GPGGVAAAAKSAAKVAAK 542 +A G+ PG PG PG A G PG GP G AA + K Sbjct: 1324 LA-GLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEK 1382 Query: 543 AQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALA--------- 593 RA G G G VG PG G PG +G PG VPG++ Sbjct: 1383 G--RAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIK 1440 Query: 594 -----------AAKAAKYG---------AAVPGVLGGLGALGGVGIPGGVVGAGPAAAAA 633 + A Y AA PG G G G G PG P + Sbjct: 1441 RFIRQEIIKMFDERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPG-----APGSPGL 1495 Query: 634 AAKAAAKAAQFGLVGAAGLGGL----GVGGLGVPGVGGLGGIP-PAAAAKAAKYGVAARP 688 + + Q GL G GL G G G+G+ G GL G P P K G Sbjct: 1496 PGQIGREGRQ-GLPGVRGLPGTKGEKGDIGIGIAGENGLPGPPGPQGPPGYGKMGATGPM 1554 Query: 689 GFGLSPIFPG 698 G P PG Sbjct: 1555 GQQGIPGIPG 1564 Score = 137 bits (346), Expect = 3e-32 Identities = 211/712 (29%), Positives = 254/712 (35%), Gaps = 150/712 (21%) Query: 89 GALVPGGVADAAA--AYKAAKAGAGLGGVPGVGG----------LGVSAAPSVPGAVVPQ 136 GAL P G+ + K K G+ GVPG G +G PG V P+ Sbjct: 384 GALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGPKGQKGDPGFVGPE 443 Query: 137 -----PGAGVKPGKVPGVGLPGVY--PGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGG 189 PG PG PG+GLPG PGG G +PG G G KP PGV G Sbjct: 444 GLAGEPGPPGLPGP-PGIGLPGTPGDPGGPPGPKGDKGSSGIPG-KEGPGGKPGKPGVKG 501 Query: 190 A-----------------FAGIPGV-GPFGGPQPGVPL-------------GYP-IKAPK 217 F G+PG GP G P VP G P + Sbjct: 502 EKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSS 561 Query: 218 LPG-----------------GYGLPYTTGK--LPYGYGPGGVAGAAGKAGYPTGTG-VGP 257 + G G+GLP G+ +P G G G AG AG P G VGP Sbjct: 562 VVGAQHLVSSTGASGDVGSPGFGLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGP 621 Query: 258 QAAAAAAAK------AAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAA 311 A + A + G V+ G +G G PG G G P Sbjct: 622 AGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGEPGP-------PGFGLPGKQGK 674 Query: 312 AAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AGVPGVGVPGA----------GIPVVP 360 A + G A PG PG PG G PG +G PGV P P + Sbjct: 675 AGERGLKGQKGDAGN--PGDPGT-PGTTGRPGLSGEPGVQGPAGPKGEKGDGCTACPSLQ 731 Query: 361 GAGIPGAAVPGVVSP--EAAAKAAAKAAKYGARPGV-GVGGIPTY-GV-GAGGFPGFGV- 414 G A PG P E + + K G +PG+ GV G P GV G G PG GV Sbjct: 732 GTVTDMAGRPGQPGPKGEQGPEGVGRPGKPG-QPGLPGVQGPPGLKGVQGEPGPPGRGVQ 790 Query: 415 GVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAA 474 G G PG G+PG+ G+PG G PG AQ + K A VG P A+ + + Sbjct: 791 GPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDG 850 Query: 475 QFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVG--VAPGVGVAPGVGVAPGIGPGGVAAA 532 Q G G+ PG G PG P G + G+ APG+ + PG Sbjct: 851 QQGQT-GLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGP- 908 Query: 533 AKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGAL 592 GIPG GVPGL GVPG G PG A G+L Sbjct: 909 --------------------PGIPGPPGPPGVPGL---QGVPGNNGLPGQPGLTAELGSL 945 Query: 593 ---------AAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQ 643 + A PG L G G GIP GV G A + +A + Sbjct: 946 PIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIP-GVPGLDNCAQCFLSLERPRAEE 1004 Query: 644 FGLVGAAGLGGLGVGGLGVPGVGGLGGI-----PPAAAAKAAKYGVAARPGF 690 + G G VG G+PG GL G PP G PGF Sbjct: 1005 ARGDNSEGDPGC-VGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGF 1055 Score = 128 bits (322), Expect = 2e-29 Identities = 233/822 (28%), Positives = 279/822 (33%), Gaps = 171/822 (20%) Query: 10 RPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPG-AGLGALG---------------- 52 RPG + ++ PG V G PG PG G+G G Sbjct: 421 RPGEICVIGPKGQKGDPGFVGPEGLAGEPGPPGLPGPPGIGLPGTPGDPGGPPGPKGDKG 480 Query: 53 ----GGALGPGGKPLKPVPGGLAG------AGLGAGLGAFPAVTFPGALVPGGVADAAAA 102 G GPGGKP KP G G L G F V PG P G Sbjct: 481 SSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNF--VGLPGKPGPKGEPGDPV- 537 Query: 103 YKAAKAGAGLGGVPGVGGLGVSAAPSVPGA--VVPQPGAGVKPGKVPGVGLPGVYPGGVL 160 A+ G+ G+ G G + SV GA +V GA G PG GLPG+ + Sbjct: 538 --PARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGS-PGFGLPGLPGRAGV 594 Query: 161 PGAR-----FPGVGVL-----PGVPTGAGVK-------PKAPGVGGAFAGIPGVGPFGGP 203 PG + F G PG AG+K P + G V GP Sbjct: 595 PGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGP 654 Query: 204 -----QPGVP-LGYPIKAPKL--------------PGGYGLPYTTGKLPYGYGPGGVAGA 243 +PG P G P K K PG G P TTG+ P G GV G Sbjct: 655 SGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGR-PGLSGEPGVQGP 713 Query: 244 AGKAGYP-TGTGVGPQAAAAAAAKAAAKFGAGAAGVL--PGVGGAGVPGVPGAIPGIGGI 300 AG G G P A G G GVG G PG PG +PG+ G Sbjct: 714 AGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQPG-LPGVQGP 772 Query: 301 AGV----GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AGVPG-VGVPGA 354 G+ G P + PG PG PG+ G+PG G PG G GA Sbjct: 773 PGLKGVQGEPGPPGRGVQGPQGE---------PGAPGL-PGIQGLPGPRGPPGPTGEKGA 822 Query: 355 -GIPVVPGA----GIPGAAV---PGVVSPEAAAKAAAKAAKYGAR-----PG-------- 393 G P V GA G PGA+V PG + + G R PG Sbjct: 823 QGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQG 882 Query: 394 ----VGVGGIPTYGVGAGGFPG--FGVGVGGIPGVAGVPGVGGVPGVGGVPG-------V 440 G+ G P +G+ PG G+ G PG GVPG+ GVPG G+PG + Sbjct: 883 DLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAEL 942 Query: 441 GISPEAQ------------------AAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGV 482 G P Q K K G P A+ P Sbjct: 943 GSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRA 1002 Query: 483 GVAPGVGVA--PGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG----IGPGGVAAAAKSA 536 A G PG +PG+ PG+ G PG+ +PG IGP G A S Sbjct: 1003 EEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGS- 1061 Query: 537 AKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAK 596 G+PGL G+ GL G PG G PG PG L K Sbjct: 1062 ----------------PGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPG-LPGIK 1104 Query: 597 AAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLG 656 + G G G G G+PG AGP + + G G G G Sbjct: 1105 GERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPG-P 1163 Query: 657 VGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPG 698 G G PG G G PP A+ G+ G SP PG Sbjct: 1164 PGPPGFPGKVGSPG-PPGPQAEKGSEGIRGPSGLPGSPGPPG 1204 Score = 102 bits (253), Expect = 2e-21 Identities = 217/757 (28%), Positives = 256/757 (33%), Gaps = 135/757 (17%) Query: 17 LLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLG 76 L+S S G PG G+PG PG G GP G P P P G AG Sbjct: 568 LVSSTGASGDVGSPGFGLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGA 627 Query: 77 AGLGAFPAVTF-------------------------PGALVPGGVADAAA-AYKAAKAGA 110 G P PG +PG A K K A Sbjct: 628 KGEPCEPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDA 687 Query: 111 GLGGVPGVGGL----GVSAAPSVPGAVVPQPGAGVKPGKVPGV--------GLPGVYPGG 158 G G PG G G+S P V G P+ G P + G PG PG Sbjct: 688 GNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPG-QPGP 746 Query: 159 VLPGARFP-GVGVLPGVPTGAGVKPKAPGVGGAFAGIPGV-GPFGGPQPGV--PLGYPIK 214 G + P GVG PG P +P PGV G G+ GV G G P GV P G P Sbjct: 747 --KGEQGPEGVG-RPGKPG----QPGLPGVQGP-PGLKGVQGEPGPPGRGVQGPQGEP-G 797 Query: 215 APKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTG-VGPQAAAAAA--AKAAAKF 271 AP LPG GLP G GP G GA G G TG VGP A+ + + + Sbjct: 798 APGLPGIQGLPGPRGPP----GPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQG 853 Query: 272 GAGAAGVLPGVGGAGVPGVPG--AIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVP 329 G G G G G PG + P G + G P A G++ P Sbjct: 854 QTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWM--------GSSWQPGP 905 Query: 330 GGPGFGPGVVGVPGA-GVPGV-GVPGA-GIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAA 386 GP PG+ G PG GVPG+ GVPG G+P PG ++P + K+ Sbjct: 906 QGP---PGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLP---IEQHLLKSICGDC 959 Query: 387 KYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVP-------------------- 426 G R P Y V G G GIPGV G+ Sbjct: 960 VQGQRAH------PGYLVEKGE-----KGDQGIPGVPGLDNCAQCFLSLERPRAEEARGD 1008 Query: 427 ---GVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVG 483 G G G G+PG P + + G P A +PG+ Sbjct: 1009 NSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQ 1068 Query: 484 VAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI-GPGGVAAAAKSAAKVAAK 542 G+ G PG PG PG PG+ PGI G G +A + Sbjct: 1069 GERGLTGLTGDKGEPG---PPGQPGYPGATGPPGL---PGIKGERGYTGSAGEKGEPGPP 1122 Query: 543 AQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALA-AAKAAKYG 601 + GL G PG G G +G G G PGF PG K G Sbjct: 1123 ----GSEGL-PGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPG 1177 Query: 602 AAVP-------GVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGG 654 P G+ G G G G PG GPA K G G AG G Sbjct: 1178 PPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPG 1237 Query: 655 LGVGGLGVPGVGGLGGI--PPAAAAKAAKYGVAARPG 689 L +G G G G G+ P K G RPG Sbjct: 1238 L-MGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPG 1273 Score = 100 bits (249), Expect = 5e-21 Identities = 146/455 (32%), Positives = 176/455 (38%), Gaps = 78/455 (17%) Query: 25 RPG--GVPGAIPGGVPGGVFYPGA-GLGALGG--GALGPGGKPLKPVPGGLAGAGLGAGL 79 +PG G PG P G PG V PG G A G G GP G P P P G G AGL Sbjct: 1157 QPGFPGPPG--PPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGL 1214 Query: 80 GAFPAVTFPGALVPGGVADAAAAYKAAKAGA----GLGGVPGVGG-LGVSAAPSVPGAVV 134 PG D A G G G PG+ G G P PG+ Sbjct: 1215 DGLDGKDGK----PGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGST- 1269 Query: 135 PQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGG----- 189 +PGA +PG + G PG PG V P PG PG P AG+ A G+ G Sbjct: 1270 GRPGAEGEPGAMGPQGRPGP-PGHVGP----PGP---PGQPGPAGIS--AVGLKGDRGAT 1319 Query: 190 ---AFAGIPGV-GPFGGPQPGVPLGYPIKA-----PKLPGGYGLPYTTGKLPYGYGPGGV 240 AG+PG GP G P P G A P G YG P G P G G Sbjct: 1320 GERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGD-PGAAGQKGQ 1378 Query: 241 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGA-GVPGVPGAIPGIGG 299 AG G+AG P G G A + G A PG G+ G+PGVPG++ + Sbjct: 1379 AGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGA---PGPSGSPGLPGVPGSMGDMVN 1435 Query: 300 IAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPGVGVPGA-GIP 357 + + Y + P PG G PG G PG PGA G P Sbjct: 1436 YDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGR--PGAPGSP 1493 Query: 358 VVPGA-------GIPGA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGV----G 405 +PG G+PG +PG G + +G+G G+ G Sbjct: 1494 GLPGQIGREGRQGLPGVRGLPGTK---------------GEKGDIGIGIAGENGLPGPPG 1538 Query: 406 AGGFPGFG-VGVGGIPGVAGVPGVGGVPGVGGVPG 439 G PG+G +G G G G+PG+ G PG G PG Sbjct: 1539 PQGPPGYGKMGATGPMGQQGIPGIPGPPGPMGQPG 1573 Score = 94.0 bits (232), Expect = 4e-19 Identities = 143/521 (27%), Positives = 176/521 (33%), Gaps = 103/521 (19%) Query: 236 GPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIP 295 G G +GA G +G P TG Q K G G+ G G G PG I Sbjct: 378 GEKGESGALGPSGLPGSTGEKGQ-----------KGEKGDGGIKGVPGKPGRDGRPGEIC 426 Query: 296 GIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFG-PGVVGVPG----------- 343 IG G P A + G +PG PG G PG G PG Sbjct: 427 VIGPKGQKGDPGFVGPEGLAGEPGPPG-----LPGPPGIGLPGTPGDPGGPPGPKGDKGS 481 Query: 344 AGVPGVGVPG-----------------------------AGIPVVPG-AGIPGAAVPGVV 373 +G+PG PG G+P PG G PG VP Sbjct: 482 SGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPVPARG 541 Query: 374 SP-------EAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVP 426 P E + ++ GA+ V G G G PGF G+ G+PG AGVP Sbjct: 542 DPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTG----ASGDVGSPGF--GLPGLPGRAGVP 595 Query: 427 GVGGVPGVGGVPGVGISPEAQ---AAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVG 483 G+ G G G G SP A K AK P A + + +PG Sbjct: 596 GLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPS 655 Query: 484 VAPGVGVAPGVGVAPGVGLA--------------PGVGVAPGVGVAPGVGVAPGI-GPGG 528 G PG G+ G A PG PG PG+ PG+ GP G Sbjct: 656 GEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAG 715 Query: 529 VAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAV 588 + A L+ AG PG G G G G PG G+PG Sbjct: 716 --PKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQG-PEGVGRPGKPGQPGLPGVQGP 772 Query: 589 PGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVG 648 PG + G GV G G G G+PG + P K AQ G Sbjct: 773 PGLKGV--QGEPGPPGRGVQGPQGEPGAPGLPG--IQGLPGPRGPPGPTGEKGAQ----G 824 Query: 649 AAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPG 689 + G+ G G +G PG G PP + + G+ PG Sbjct: 825 SPGVKG-ATGPVGPPGASVSG--PPGRDGQQGQTGLRGTPG 862 Score = 63.5 bits (153), Expect = 6e-10 Identities = 99/320 (30%), Positives = 113/320 (35%), Gaps = 73/320 (22%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGL----GALG----GGALGPGGKPLKPVPGGLAGAG 74 P PG V P G PG GL GA G G G G P P P G G Sbjct: 1287 PGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTD 1346 Query: 75 LGAGLGAFPAVT-FPGALVPGGVADAAAAYKAAKAG----AGLGGVPGVGGLGVSAAPSV 129 AG P F G PG D AA + +AG AG+ G PG G P Sbjct: 1347 GAAGKEGPPGKQGFYGP--PGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPG 1404 Query: 130 PGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVG-------------------- 169 P PGA PG GLPGV PG + + + Sbjct: 1405 PAGERGHPGA---PGPSGSPGLPGV-PGSMGDMVNYDEIKRFIRQEIIKMFDERMAYYTS 1460 Query: 170 --VLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPK-----LPGGY 222 P A +P PG GA G PG PG P G P + + LPG Sbjct: 1461 RMQFPMEMAAAPGRPGPPGKDGA-PGRPGA-------PGSP-GLPGQIGREGRQGLPGVR 1511 Query: 223 GLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGV 282 GLP T G+ G G+AG G G P GPQ G G G + Sbjct: 1512 GLPGTKGE--KGDIGIGIAGENGLPGPP-----GPQGPP----------GYGKMGATGPM 1554 Query: 283 GGAGVPGVPGAIPGIGGIAG 302 G G+PG+PG PG G G Sbjct: 1555 GQQGIPGIPGP-PGPMGQPG 1573 Score = 56.2 bits (134), Expect = 1e-07 Identities = 105/381 (27%), Positives = 132/381 (34%), Gaps = 75/381 (19%) Query: 327 LVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIPGAAVPGVV--SPEAAAKAAAK 384 L P GP G G G+PG PG+ G GA V SP+A + A Sbjct: 330 LAPSGPKGGKGERGLPGP-------PGS-------KGEKGARGNDCVRISPDAPLQCAE- 374 Query: 385 AAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISP 444 G + G G +G G+PG G G G G GG+ GV P Sbjct: 375 ----GPKGEKGESG--------------ALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKP 416 Query: 445 EAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAP 504 G K F G+ PG PG+ PG+GL P Sbjct: 417 GRDGRP---------GEICVIGPKGQKGDPGFVGPEGLAGEPG---PPGLPGPPGIGL-P 463 Query: 505 GVGVAPGVGVAP-----GVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIP-GL 558 G PG P G+ GPGG K K + + +P G Sbjct: 464 GTPGDPGGPPGPKGDKGSSGIPGKEGPGG------KPGKPGVKGEKGDPCEVCPTLPEGF 517 Query: 559 GVGVGVPGLGVGAGVPGLGVGA----GVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGAL 614 VG+PG G PG V A G+ G G + ++ GA ++ GA Sbjct: 518 QNFVGLPGKPGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGA--QHLVSSTGAS 575 Query: 615 GGVGIPG-GVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIP- 672 G VG PG G+ G A K + FG G AG G G +G G+ G G P Sbjct: 576 GDVGSPGFGLPGLPGRAGVPGLK--GEKGNFGEAGPAGSPG-PPGPVGPAGIKGAKGEPC 632 Query: 673 -PAAAAKAAKYG---VAARPG 689 P A + G V A PG Sbjct: 633 EPCPALSNLQDGDVRVVALPG 653 Score = 44.7 bits (104), Expect = 3e-04 Identities = 61/200 (30%), Positives = 74/200 (37%), Gaps = 30/200 (15%) Query: 500 VGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLG 559 V LAP G G G G+ PG G A +++ A L+ A G G G Sbjct: 328 VTLAPS-GPKGGKGER-GLPGPPG-SKGEKGARGNDCVRISPDAPLQCAEG-PKGEKGES 383 Query: 560 VGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGI 619 +G GL G G G G VPG K + G PG + +G G G Sbjct: 384 GALGPSGLPGSTGEKGQKGEKGDGGIKGVPG-----KPGRDGR--PGEICVIGPKGQKGD 436 Query: 620 PGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL-GVGGLGVPGVGGLGGIPPAAAAK 678 PG V GP GL G G GL G G+G+PG G G PP Sbjct: 437 PGFV---GPE---------------GLAGEPGPPGLPGPPGIGLPGTPGDPGGPPGPKGD 478 Query: 679 AAKYGVAARPGFGLSPIFPG 698 G+ + G G P PG Sbjct: 479 KGSSGIPGKEGPGGKPGKPG 498 >gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] Length = 1690 Score = 139 bits (349), Expect = 1e-32 Identities = 225/769 (29%), Positives = 276/769 (35%), Gaps = 166/769 (21%) Query: 11 PGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGA----GLGALGGGALGPGGKPLKPV 66 PG ++ S+ +P P G+ G + G PGG G GL A G +GP G P P Sbjct: 453 PGSSVIYCSVGNPG-PQGIKGKV--GPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPG 509 Query: 67 PGGLAG-AGLGAGLGAFPAVTFPGALVPGGV-----ADAAAAYKAAKAGAGLGGVPG-VG 119 G G GL LG PGA P G+ A K AK + V G G Sbjct: 510 RQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKG 569 Query: 120 GLGVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGG---VLPGAR-FPGVGVLPGVP 175 G P PG QPG+ + G G PG PG PG + FPG P P Sbjct: 570 ERGPDGPPGFPG----QPGSHGRDGHAGEKGDPGP-PGDHEDATPGGKGFPG----PLGP 620 Query: 176 TGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYP-IKAPK-LPGGYGLPYTTG-KLP 232 G PG+G F G PG PGVP G+P ++ P L G G + P Sbjct: 621 PGKAGPVGPPGLG--FPGPPGERG----HPGVP-GHPGVRGPDGLKGQKGDTISCNVTYP 673 Query: 233 YGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG 292 +GP G G G G+P GPQ A + K G G A +PG PG Sbjct: 674 GRHGPPGFDGPPGPKGFP-----GPQGAPGLSGSDGHKGRPGTPGT------AEIPGPPG 722 Query: 293 -----AIPGIGGIAG---VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG- 343 PG GG G VG P + + +PG P FG +G PG Sbjct: 723 FRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKG--------IPGDPAFGH--LGPPGK 772 Query: 344 ---AGVPGVGVPGAGIPVVPGA----GIPG-------------AAVPGVVSPEAAAKAAA 383 +GVPG+ P G P PGA GIPG A PGV P Sbjct: 773 RGLSGVPGIKGP-RGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPG------ 825 Query: 384 KAAKYGARPGV-GVGGIPTYGVGAGGFPGFG----------VGVGGIPGVAGVPGVGGVP 432 + + GA PG+ G G+P Y G G G G+ G+PG+ G PG G P Sbjct: 826 HSCERGA-PGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPP 884 Query: 433 GVGGVPGVGISPEAQAAAAAKAAKYG-VGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVA 491 G+ G+PG +G G P K F PG PG Sbjct: 885 GLPGIPG----------------PFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGC 928 Query: 492 PGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGL 551 PG PG G+ G+ A G IGP G ++A +Q Sbjct: 929 PGAKGEPGEKGMSGLPGDRGLRGAKG-----AIGPPG------DEGEMAIISQKGTPGEP 977 Query: 552 GA----GIPGLGVGVGVPGLGVGAGVPGL----GVGAGVPGFGAVPG-----ALAAAKAA 598 G G PG G PG+ G PG G G PG PG + Sbjct: 978 GPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGL 1037 Query: 599 KYGAAVPGVLGGLGALGGVGIPG--GVVGA--------------GPAAAAAAAKAAAKAA 642 + PG+ G G G G PG G+ GA GP + Sbjct: 1038 RGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPG 1097 Query: 643 QFGLVGAAGLGGL--GVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPG 689 FG G GL G+ G G PG G G PP G+ +PG Sbjct: 1098 HFGASGEQGLPGIQGPRGSPGRPGPPGSSG-PPGCPGDHGMPGLRGQPG 1145 Score = 134 bits (338), Expect = 2e-31 Identities = 234/794 (29%), Positives = 275/794 (34%), Gaps = 148/794 (18%) Query: 22 HPSRPG--GVPGAIP-GGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAG---L 75 HP PG G PG G G +PG G GALGPGG P G G L Sbjct: 126 HPGPPGPRGKPGMSGHNGSRGDPGFPG------GRGALGPGGPLGHPGEKGEKGNSVFIL 179 Query: 76 GAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGL-GVSAAPSVPGAVV 134 GA G PG +PG A AG G PG GL G P PG + Sbjct: 180 GAVKGIQGDRGDPG--LPG-----LPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPG-LK 231 Query: 135 PQPGAGVK-----PGKVPGVGLPG-----------VYPG--GVLPGARFPGVGVLPGVP- 175 PG GVK PG+V G PG +Y G G+ PG+ LPG P Sbjct: 232 GNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGI---KGIPGMVGLPGPPG 288 Query: 176 ----TGAGVK--------------------PKAPGVGG--AFAGIPG----VGPFGGP-- 203 +G G K P PG+ G G PG +GP G P Sbjct: 289 RKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGN 348 Query: 204 -----QPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQ 258 PGV + P+ PG G P G+ GP G G G+ G +GP Sbjct: 349 RGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETG-DVGPPGPPGLLGRPGEACAGMIGPP 407 Query: 259 AAAAAAAKAAAKFGAGAAG---VLPG-VGGAGVPGVPGAIPGIGGIAG-------VGTPA 307 AG G PG G G PG+PGA PG+ G+ G VG P Sbjct: 408 GPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGA-PGLQGLPGSSVIYCSVGNPG 466 Query: 308 AAAAAAAAAKAAKYGAAAGLVPGGP-------GFGPGVVGVPG-AGVPG-------VGVP 352 K G G P G PG +G PG G+PG +G+P Sbjct: 467 PQGI------KGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLP 520 Query: 353 G----AGIPVVPGA----GIPG----AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIP 400 G G P PGA G+PG + PG + + G R G G P Sbjct: 521 GWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFP 580 Query: 401 ----TYG----VGAGGFPG-FGVGVGGIPGVAGVPGVGGVPGVG---GVPGVGI-SPEAQ 447 ++G G G PG G PG G PG G PG G PG+G P + Sbjct: 581 GQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGE 640 Query: 448 AAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVG 507 GV P + + PG PG PG PG APG+ Sbjct: 641 RGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLS 700 Query: 508 VAPGVGVAPGV-GVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPG 566 + G PG G A GP G K G PG+ G+PG Sbjct: 701 GSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPG 760 Query: 567 LGV--GAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVV 624 G PG +GVPG P A+ A +PG LG G G G G Sbjct: 761 DPAFGHLGPPGKRGLSGVPGIKG-PRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPG 819 Query: 625 GAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGV 684 GP + A Q GL G G G GG G PG G PP A G+ Sbjct: 820 VPGPPGHSCERGAPGIPGQPGLPGYPGSPG-APGGKGQPGDVG----PPGPAGMKGLPGL 874 Query: 685 AARPGFGLSPIFPG 698 RPG P PG Sbjct: 875 PGRPGAHGPPGLPG 888 Score = 134 bits (336), Expect = 4e-31 Identities = 237/831 (28%), Positives = 290/831 (34%), Gaps = 198/831 (23%) Query: 22 HPSRPGG------VPGAIPG-----GVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGL 70 HP G + GA+ G G PG PG+ GA GG GP G P +P G Sbjct: 165 HPGEKGEKGNSVFILGAVKGIQGDRGDPGLPGLPGSW-GA--GGPAGPTGYPGEPGLVGP 221 Query: 71 AGAGLGAGLGAFPAVTFPGAL-VPGGVADAAA-------------AYKAAKAGAGLGGVP 116 G GL P V G + PG V + YK K G+ G+ Sbjct: 222 PGQPGRPGLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMV 281 Query: 117 GV---------GGLGVSAAPSVPGAVVPQ--PGAGVKPGKVPG-------VGLPGVY--- 155 G+ G+G +PG P+ PG+ PG PG VG PG++ Sbjct: 282 GLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPG-FPGLKGELGLVGDPGLFGLI 340 Query: 156 -PGGVLPGARF----PGVGVLPGVP----------------TGAGVKPKAPGV----GGA 190 P G PG R PGV V P +P TG P PG+ G A Sbjct: 341 GPKGD-PGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEA 399 Query: 191 FAGIPG-VGPFGGP-QPGVP-----LGYPIKAPKLPGGYGLPYTTGK-----LP------ 232 AG+ G GP G P PG+P G P AP PG G P G LP Sbjct: 400 CAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIY 459 Query: 233 YGYGPGGVAGAAGKAGYPTGTG-----------------VGPQAAAAAAAKAAAKFGAGA 275 G G G GK G P G G +GP + +K G Sbjct: 460 CSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGL 519 Query: 276 AGVL-----PGVGGA-GVPGVPG-----AIPGIGGIAG-------------------VGT 305 G L PG GA G PG+PG PG G G G Sbjct: 520 PGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGF 579 Query: 306 PAAAAAAAAAAKAAKYGAAA------GLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVV 359 P + A + G PGG GF PG +G PG P VG PG G P Sbjct: 580 PGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGF-PGPLGPPGKAGP-VGPPGLGFPGP 637 Query: 360 PG----AGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFG-- 413 PG G+PG PGV P+ + G + TY G G PGF Sbjct: 638 PGERGHPGVPGH--PGVRGPDGLK----------GQKGDTISCNVTY-PGRHGPPGFDGP 684 Query: 414 VGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKA 473 G G PG G PG+ G G G PG +P + +G P K ++ Sbjct: 685 PGPKGFPGPQGAPGLSGSDGHKGRPG---TPGTAEIPGPPGFRGDMGDPGFGGEKGSSPV 741 Query: 474 AQFGLVPGVGVAPGVGVAPGVGVAPGVG-LAP----GVGVAPGVGVAPGVGVAPGI-GPG 527 PG +PGV G+ P G L P G+ PG+ G PG GP Sbjct: 742 GP----PGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPA 797 Query: 528 GVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGA 587 G+ K + A G PG G PG+ G+PG G PG Sbjct: 798 GIPGFL--GLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKG 855 Query: 588 VPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPG--------GVVG-AGPAAAAAAAKAA 638 PG + A +PG+ G GA G G+PG G+ G GP Sbjct: 856 QPGDVGPPGPAGM-KGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFP 914 Query: 639 AKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPG 689 + G GA G G G PG G+ G+P + AK G PG Sbjct: 915 GFPGERGKPGAEGC----PGAKGEPGEKGMSGLPGDRGLRGAK-GAIGPPG 960 Score = 132 bits (333), Expect = 8e-31 Identities = 231/784 (29%), Positives = 273/784 (34%), Gaps = 159/784 (20%) Query: 22 HPSRPGGVPGA--IPG--GVPGGVFYPGAGLGALGGGALGPGGKPLKP-------VPGGL 70 H RPG PG IPG G G + PG G G G +GP G P P +PG Sbjct: 705 HKGRPG-TPGTAEIPGPPGFRGDMGDPGFG-GEKGSSPVGPPGPPGSPGVNGQKGIPGDP 762 Query: 71 AGAGLGA----GLGAFPAVT-------FPGALVPGGVAD--AAAAYKAAKAGAGLGGVPG 117 A LG GL P + PGA P G+ K + AG GVPG Sbjct: 763 AFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPG 822 Query: 118 VGGLGVS-AAPSVPGAVVPQPGAGVKPGKVPGVGLPG-VYPGGVLPGARFPGVGVLPGVP 175 G AP +PG PG PG G G PG V P G PG LPG P Sbjct: 823 PPGHSCERGAPGIPGQP-GLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPG---LPGRP 878 Query: 176 TGAGVKPKAPGVGGAFA--GIPGVGPFGGPQ--PGVPLGYPIKAPKLPGGYGLPYTTGK- 230 GA P PG+ G F G+PG GP+ PG P G+P + K PG G P G+ Sbjct: 879 -GAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFP-GFPGERGK-PGAEGCPGAKGEP 935 Query: 231 -------LPYGYGPGGVAGAAGKAGYPTGTGV-------------GPQAAAAAAAKAAAK 270 LP G G+ GA G G P G GP + K Sbjct: 936 GEKGMSGLP---GDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDK 992 Query: 271 -------------------FGAGAAGVLPGVGGAGVPGVPGA--------IPGIGGIAGV 303 F G G G G PG PG+ PG+ G G Sbjct: 993 GTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGE 1052 Query: 304 -GTPA----AAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-------AGVPGVGV 351 G+P + A K K A+ P GP PG G PG G+PG+ Sbjct: 1053 PGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQG 1112 Query: 352 P--GAGIPVVPGA-GIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIP-TYGV-GA 406 P G P PG+ G PG PG + G R G GIP G+ G Sbjct: 1113 PRGSPGRPGPPGSSGPPGC--PGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGP 1170 Query: 407 GGFPGFGVGVGGIPGVAGVPGVGGV-----PGVGGVPGV----------GISP---EAQA 448 G PG G+ G+ G G G G+ PG G+PG+ GISP + Sbjct: 1171 SGSPGLN-GLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKK 1229 Query: 449 AAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGV-GLAPGVG 507 G PA A +A G PG PG G PG+ G + Sbjct: 1230 GPPGPPGSSGPPGPAGATGRAPKDIPDPG-PPGDQGPPGPDGPRGAPGPPGLPGSVDLLR 1288 Query: 508 VAPGVGVAPGVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRAAAGLGA-GIPGLGVGVGVP 565 PG PG PG GP G K K + G G PG G+P Sbjct: 1289 GEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLP 1348 Query: 566 GLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVG 625 G PG G+PG PG A +PG G G G +G+PG Sbjct: 1349 G------PPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGP 1402 Query: 626 AGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVA 685 +GP G G GL G GV GV G G PP + G Sbjct: 1403 SGP----------------GCKGEPGLD----GRRGVDGVPGSPG-PPGRKGDTGEDGYP 1441 Query: 686 ARPG 689 PG Sbjct: 1442 GGPG 1445 Score = 125 bits (315), Expect = 1e-28 Identities = 202/670 (30%), Positives = 233/670 (34%), Gaps = 125/670 (18%) Query: 23 PSRPG--GVPGAIPG-GVPGGVFYPG-AGLGALGG-----GALGPGGKPLKPVPGGLAGA 73 P PG G PGA G G PG V PG AG+ L G GA GP G P +PG Sbjct: 839 PGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLP--GIPGPFGDD 896 Query: 74 GLGA--------GLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGL-GVS 124 GL GL FP FPG G A+ K G+ G+PG GL G Sbjct: 897 GLPGPPGPKGPRGLPGFPG--FPGERGKPG-AEGCPGAKGEPGEKGMSGLPGDRGLRGAK 953 Query: 125 AAPSVPG-----AVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAG 179 A PG A++ Q G +PG G PG PG + G Sbjct: 954 GAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQ------------GRR 1001 Query: 180 VKPKAPGVGGAFAGIPGV----GPFGGPQPGVPLGYP--IKAPKLPGGYGLPYTTGKLPY 233 +P G G G PG GP G P P G I P LPG G P + G P Sbjct: 1002 GEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPG--PP 1059 Query: 234 GY-GPGGVAGAAGKAGYPTGT--GVGPQAAAAAAAKAAAKFGAGAAGVLPGV----GGAG 286 G+ G G G G G P GP+ + FGA LPG+ G G Sbjct: 1060 GFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPG-CPGHFGASGEQGLPGIQGPRGSPG 1118 Query: 287 VPGVPGA-----IPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVG 340 PG PG+ PG G+ G+ G P G GP PG+ G Sbjct: 1119 RPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNG 1178 Query: 341 VPG---------------AGVPG-VGVPGA----GIPVVPGAGIPGA-------AVPGVV 373 + G G PG VG+PG G P PG PG PG Sbjct: 1179 LHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSS 1238 Query: 374 SPEAAAKAAAKAAKYGARPGV-------GVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVP 426 P A A +A K PG G G P G G PG + G PG G+P Sbjct: 1239 GPPGPAGATGRAPKDIPDPGPPGDQGPPGPDG-PRGAPGPPGLPGSVDLLRGEPGDCGLP 1297 Query: 427 GVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAP 486 G G PG G PG P K VG P F PG P Sbjct: 1298 GPPGPPGPPGPPGYKGFPGCDGKDGQKGP---VGFPGPQGPHG------FPGPPGEKGLP 1348 Query: 487 GVGVAPGVGVAPGVGLAPG----VGVAPGVGVAPGVGVAPGI-GPGGVAAAAKSAAKVAA 541 G G PG PG V P + PG+ APG+ GP G Sbjct: 1349 GPPGRKGPTGLPGPRGEPGPPADVDDCPRI---PGLPGAPGMRGPEGAMGL--------- 1396 Query: 542 KAQLRAAAGLGA-GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKY 600 +R +G G G PGL GV G+ G PG G G+ PG Sbjct: 1397 -PGMRGPSGPGCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGPIGDPGP 1455 Query: 601 GAAVPGVLGG 610 PG LGG Sbjct: 1456 KGFGPGYLGG 1465 Score = 111 bits (277), Expect = 3e-24 Identities = 208/712 (29%), Positives = 247/712 (34%), Gaps = 131/712 (18%) Query: 28 GVPGAI-------PGGVPGGVFYPGAGLGALGG--GALGPGGKPLKPVPGGLAGAGLGAG 78 G PGA P GVPG +PG L + G G GP GKP G++G G Sbjct: 98 GPPGAAGDKGDKGPTGVPG---FPG--LDGIPGHPGPPGPRGKP------GMSGHNGSRG 146 Query: 79 LGAFPAVTFPGALVPGGVADAAAAYKAAKAGAG-----LGGVPGV-GGLGVSAAPSVPGA 132 FP GAL PGG + K G LG V G+ G G P +PG+ Sbjct: 147 DPGFPGGR--GALGPGG----PLGHPGEKGEKGNSVFILGAVKGIQGDRGDPGLPGLPGS 200 Query: 133 VVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVG-GAF 191 GAG G P YPG PG+ PG P G+K PGVG Sbjct: 201 W----GAGGPAG-------PTGYPGE-------PGLVGPPGQPGRPGLKGN-PGVGVKGQ 241 Query: 192 AGIPG-VGPFGGPQPGVPLGYP----IKAPK----LPGGYGLPYTTGKLPYGYGPGGVAG 242 G PG VG G P P + + P K K +PG GLP G+ G G G Sbjct: 242 MGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRK--GESGIGAKG 299 Query: 243 AAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAG 302 G G+P GP+ + G G L VG G+ G+ G G Sbjct: 300 EKGIPGFP-----GPRGDPGSYGSPGFP---GLKGELGLVGDPGLFGLIGPKGDPGNRGH 351 Query: 303 VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGA 362 G P K PG PGF PG G G VG PG PG Sbjct: 352 PGPPGVLVTPPLPLKGP---------PGDPGF-PGRYGETG----DVGPPGP-----PGL 392 Query: 363 -GIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPG 421 G PG A G++ P G + G+ G+P G G PG G PG Sbjct: 393 LGRPGEACAGMIGPP------------GPQGFPGLPGLP----GEAGIPGRPDSAPGKPG 436 Query: 422 VAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKA-AAKAAQFGLVP 480 G PG+ G PG+ G+PG + + + K VG P K P Sbjct: 437 KPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEP 496 Query: 481 GVGVAPGVGVAPG-VGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKV 539 G PG PG G +GL +G G PG PG+ PG A+ K Sbjct: 497 GPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPG-PPGAEGPPGL-PGKHGASGPPGNK- 553 Query: 540 AAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAK 599 AK + G G G PG G G AG G PG A Sbjct: 554 GAKGDM--VVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPG--DHEDATP 609 Query: 600 YGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGV-- 657 G PG LG G G VG P G+ GP G G G G + Sbjct: 610 GGKGFPGPLGPPGKAGPVG-PPGLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISC 668 Query: 658 -----------GGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPG 698 G G PG G G P A + G RPG + PG Sbjct: 669 NVTYPGRHGPPGFDGPPGPKGFPG-PQGAPGLSGSDGHKGRPGTPGTAEIPG 719 Score = 92.4 bits (228), Expect = 1e-18 Identities = 129/434 (29%), Positives = 159/434 (36%), Gaps = 69/434 (15%) Query: 279 LPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGL----VPGGPGF 334 +P G G PG PG IG + G + GAA G PGF Sbjct: 58 VPEKGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTGVPGF 117 Query: 335 GPGVVGVPG-AGVPGV-GVPG----------AGIPVVPGAGIPGAAV--PGVVSPEAAAK 380 PG+ G+PG G PG G PG G P GA PG + PG + + Sbjct: 118 -PGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPGEKGEKGNSV 176 Query: 381 AAAKAAK--YGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVP 438 A K G R G+ G+P GAGG P G G PG+ G PG G PG+ G P Sbjct: 177 FILGAVKGIQGDRGDPGLPGLPG-SWGAGG-PAGPTGYPGEPGLVGPPGQPGRPGLKGNP 234 Query: 439 GVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAP 498 GVG+ + VG + + F L G G+ PG+ P Sbjct: 235 GVGVKGQMGDPGE-------VGQQGSPGPTLLVEPPDFCLYKG---EKGIKGIPGMVGLP 284 Query: 499 GVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGL 558 G PG G+G G+ GP G + S K +L GL G PGL Sbjct: 285 G---PPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGEL----GL-VGDPGL 336 Query: 559 GVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYG-AAVPGVLGGLGALGGV 617 +G G G PG PG L G PG G G G V Sbjct: 337 FGLIGPKGDPGNRGHPG------------PPGVLVTPPLPLKGPPGDPGFPGRYGETGDV 384 Query: 618 GIPG--GVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAA 675 G PG G++G A A G++G G G G G+PG G+ G P +A Sbjct: 385 GPPGPPGLLGRPGEACA------------GMIGPPGPQGF-PGLPGLPGEAGIPGRPDSA 431 Query: 676 AAKAAKYGVAARPG 689 K K G PG Sbjct: 432 PGKPGKPGSPGLPG 445 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.314 0.143 0.440 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 38,524,015 Number of Sequences: 37866 Number of extensions: 3069825 Number of successful extensions: 62202 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 495 Number of HSP's successfully gapped in prelim test: 1005 Number of HSP's that attempted gapping in prelim test: 14651 Number of HSP's gapped (non-prelim): 13960 length of query: 711 length of database: 18,247,518 effective HSP length: 109 effective length of query: 602 effective length of database: 14,120,124 effective search space: 8500314648 effective search space used: 8500314648 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.