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Search of human proteins with 42403575
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|42403575 four and a half LIM domains 2 [Homo sapiens]
(279 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|87159836 four and a half LIM domains 2 [Homo sapiens] 632 0.0
gi|87159834 four and a half LIM domains 2 [Homo sapiens] 632 0.0
gi|42403575 four and a half LIM domains 2 [Homo sapiens] 632 0.0
gi|87159832 four and a half LIM domains 2 [Homo sapiens] 632 0.0
gi|30410801 activator of cAMP-responsive element modulator (CREM... 406 e-114
gi|54112385 four and a half LIM domains 3 [Homo sapiens] 379 e-105
gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens] 335 2e-92
gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens] 335 2e-92
gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens] 335 2e-92
gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens] 335 2e-92
gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens] 335 2e-92
gi|228480211 four and a half LIM domains 1 isoform 1 [Homo sapiens] 286 2e-77
gi|228480221 four and a half LIM domains 1 isoform 4 [Homo sapiens] 193 1e-49
gi|170932518 paxillin isoform 3 [Homo sapiens] 137 1e-32
gi|170932516 paxillin isoform 2 [Homo sapiens] 137 1e-32
gi|170932514 paxillin isoform 1 [Homo sapiens] 137 1e-32
gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo ... 120 2e-27
gi|238859658 LIM and senescent cell antigen-like domains 2 isofo... 117 1e-26
gi|238776788 LIM and senescent cell antigen-like domains 2 isofo... 117 1e-26
gi|238776786 LIM and senescent cell antigen-like domains 2 isofo... 117 1e-26
gi|40804748 LIM and senescent cell antigen-like domains 2 isofor... 117 1e-26
gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens] 112 4e-25
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens] 112 4e-25
gi|221316659 leupaxin isoform 1 [Homo sapiens] 112 5e-25
gi|4758670 leupaxin isoform 2 [Homo sapiens] 112 5e-25
gi|109638745 transforming growth factor beta 1 induced transcrip... 112 5e-25
gi|21361591 transforming growth factor beta 1 induced transcript... 112 5e-25
gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens] 109 3e-24
gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens] 109 3e-24
gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens] 105 4e-23
>gi|87159836 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 632 bits (1631), Expect = 0.0
Identities = 279/279 (100%), Positives = 279/279 (100%)
Query: 1 MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60
MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH
Sbjct: 1 MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60
Query: 61 WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS
Sbjct: 61 WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
Query: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180
SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP
Sbjct: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180
Query: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFE 240
WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFE
Sbjct: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFE 240
Query: 241 ERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI 279
ERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI
Sbjct: 241 ERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI 279
>gi|87159834 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 632 bits (1631), Expect = 0.0
Identities = 279/279 (100%), Positives = 279/279 (100%)
Query: 1 MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60
MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH
Sbjct: 1 MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60
Query: 61 WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS
Sbjct: 61 WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
Query: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180
SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP
Sbjct: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180
Query: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFE 240
WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFE
Sbjct: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFE 240
Query: 241 ERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI 279
ERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI
Sbjct: 241 ERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI 279
>gi|42403575 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 632 bits (1631), Expect = 0.0
Identities = 279/279 (100%), Positives = 279/279 (100%)
Query: 1 MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60
MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH
Sbjct: 1 MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60
Query: 61 WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS
Sbjct: 61 WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
Query: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180
SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP
Sbjct: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180
Query: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFE 240
WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFE
Sbjct: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFE 240
Query: 241 ERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI 279
ERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI
Sbjct: 241 ERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI 279
>gi|87159832 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 632 bits (1631), Expect = 0.0
Identities = 279/279 (100%), Positives = 279/279 (100%)
Query: 1 MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60
MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH
Sbjct: 1 MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60
Query: 61 WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS
Sbjct: 61 WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
Query: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180
SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP
Sbjct: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180
Query: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFE 240
WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFE
Sbjct: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFE 240
Query: 241 ERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI 279
ERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI
Sbjct: 241 ERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI 279
>gi|30410801 activator of cAMP-responsive element modulator (CREM)
in testis [Homo sapiens]
Length = 284
Score = 406 bits (1044), Expect = e-114
Identities = 165/275 (60%), Positives = 217/275 (78%)
Query: 2 TERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHW 61
T F C +C SL GKKY+L+++SPYCV C++ +F+N CEEC KPI D KDL YKDRHW
Sbjct: 3 TAHFYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHW 62
Query: 62 HEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSS 121
HE CF C++C +SLV+KPFAAK+++LLCT+CYSNE SSKC CK+TIMPG+RKME+KG+
Sbjct: 63 HEGCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNY 122
Query: 122 WHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQPW 181
WHETCF+C C+QPIGTK I K++ N+CVPC+EK+ A C CKK IT+GG+T+ +Q W
Sbjct: 123 WHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCDQLW 182
Query: 182 HKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFEE 241
HKECF+C+ CRK L ++F +RDD+ +C++C+ LYA KC C+ PISGL G K+I F++
Sbjct: 183 HKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFICFQD 242
Query: 242 RQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCG 276
QWH++CFNC KCS+SLVG+GFLT+ +I C CG
Sbjct: 243 SQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQKCG 277
Score = 78.2 bits (191), Expect = 7e-15
Identities = 33/94 (35%), Positives = 52/94 (55%), Gaps = 2/94 (2%)
Query: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIG--CDCKDLSYKDRH 60
E F C C + L ++++ R++ P+C+ C+ L+AN C C KPI K + ++D
Sbjct: 185 ECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFICFQDSQ 244
Query: 61 WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYS 94
WH CF+C +C SLV K F + ++ C C S
Sbjct: 245 WHSECFNCGKCSVSLVGKGFLTQNKEIFCQKCGS 278
>gi|54112385 four and a half LIM domains 3 [Homo sapiens]
Length = 280
Score = 379 bits (974), Expect = e-105
Identities = 149/277 (53%), Positives = 208/277 (75%)
Query: 1 MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60
M+E FDC CNESL+G+KYI + PYCV C++ FANTC EC + IG D ++L Y+DRH
Sbjct: 1 MSESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRH 60
Query: 61 WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
+HE CF C +C+ SL D+PF ++ +LLC DCY + +SS+C C +T+MPG+RK+EY G
Sbjct: 61 FHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQ 120
Query: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180
+WHE CF+C C+QP+G++SF+P ++CVPCYE + A +C +C K +T GGVTYR+QP
Sbjct: 121 TWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRDQP 180
Query: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFE 240
WH+EC VCT C+ L+GQ+FT+RD+ YC+ CF +L+A KC+ C PI GLGG KY+SFE
Sbjct: 181 WHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVSFE 240
Query: 241 ERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGK 277
+R WH++CF+C +CS SLVG+GF+ + D +LC C +
Sbjct: 241 DRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQGCSQ 277
>gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 335 bits (860), Expect = 2e-92
Identities = 135/280 (48%), Positives = 196/280 (70%), Gaps = 1/280 (0%)
Query: 1 MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60
M E+FDCH+C + L GKKY+ ++ C+ CF+ ANTC EC KPIG D K++ YK+R
Sbjct: 1 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
Query: 61 WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
WH+ CF C++C + L ++ F AK++++LC C + E S KC+ C K I+ G + +EYKG+
Sbjct: 61 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
Query: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180
WH+ CF C C+Q IGT SF PK +CV C+E + A CV+C K IT+GG+TY++QP
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180
Query: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLG-GTKYISF 239
WH +CFVC C K+L+GQRFTA +D YC++C+ + AKKCAGC NPI+G G G+ +++
Sbjct: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAY 240
Query: 240 EERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI 279
E + WH+ CF+CKKCS++L + F+ ++ + CPDC K +
Sbjct: 241 EGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKKL 280
>gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 335 bits (860), Expect = 2e-92
Identities = 135/280 (48%), Positives = 196/280 (70%), Gaps = 1/280 (0%)
Query: 1 MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60
M E+FDCH+C + L GKKY+ ++ C+ CF+ ANTC EC KPIG D K++ YK+R
Sbjct: 1 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
Query: 61 WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
WH+ CF C++C + L ++ F AK++++LC C + E S KC+ C K I+ G + +EYKG+
Sbjct: 61 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
Query: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180
WH+ CF C C+Q IGT SF PK +CV C+E + A CV+C K IT+GG+TY++QP
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180
Query: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLG-GTKYISF 239
WH +CFVC C K+L+GQRFTA +D YC++C+ + AKKCAGC NPI+G G G+ +++
Sbjct: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAY 240
Query: 240 EERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI 279
E + WH+ CF+CKKCS++L + F+ ++ + CPDC K +
Sbjct: 241 EGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKKL 280
>gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens]
Length = 309
Score = 335 bits (860), Expect = 2e-92
Identities = 135/280 (48%), Positives = 196/280 (70%), Gaps = 1/280 (0%)
Query: 1 MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60
M E+FDCH+C + L GKKY+ ++ C+ CF+ ANTC EC KPIG D K++ YK+R
Sbjct: 30 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 89
Query: 61 WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
WH+ CF C++C + L ++ F AK++++LC C + E S KC+ C K I+ G + +EYKG+
Sbjct: 90 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 149
Query: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180
WH+ CF C C+Q IGT SF PK +CV C+E + A CV+C K IT+GG+TY++QP
Sbjct: 150 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 209
Query: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLG-GTKYISF 239
WH +CFVC C K+L+GQRFTA +D YC++C+ + AKKCAGC NPI+G G G+ +++
Sbjct: 210 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAY 269
Query: 240 EERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI 279
E + WH+ CF+CKKCS++L + F+ ++ + CPDC K +
Sbjct: 270 EGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKKL 309
>gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens]
Length = 296
Score = 335 bits (860), Expect = 2e-92
Identities = 135/280 (48%), Positives = 196/280 (70%), Gaps = 1/280 (0%)
Query: 1 MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60
M E+FDCH+C + L GKKY+ ++ C+ CF+ ANTC EC KPIG D K++ YK+R
Sbjct: 17 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 76
Query: 61 WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
WH+ CF C++C + L ++ F AK++++LC C + E S KC+ C K I+ G + +EYKG+
Sbjct: 77 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 136
Query: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180
WH+ CF C C+Q IGT SF PK +CV C+E + A CV+C K IT+GG+TY++QP
Sbjct: 137 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 196
Query: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLG-GTKYISF 239
WH +CFVC C K+L+GQRFTA +D YC++C+ + AKKCAGC NPI+G G G+ +++
Sbjct: 197 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAY 256
Query: 240 EERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI 279
E + WH+ CF+CKKCS++L + F+ ++ + CPDC K +
Sbjct: 257 EGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKKL 296
>gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 335 bits (860), Expect = 2e-92
Identities = 135/280 (48%), Positives = 196/280 (70%), Gaps = 1/280 (0%)
Query: 1 MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60
M E+FDCH+C + L GKKY+ ++ C+ CF+ ANTC EC KPIG D K++ YK+R
Sbjct: 1 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
Query: 61 WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
WH+ CF C++C + L ++ F AK++++LC C + E S KC+ C K I+ G + +EYKG+
Sbjct: 61 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
Query: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180
WH+ CF C C+Q IGT SF PK +CV C+E + A CV+C K IT+GG+TY++QP
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180
Query: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLG-GTKYISF 239
WH +CFVC C K+L+GQRFTA +D YC++C+ + AKKCAGC NPI+G G G+ +++
Sbjct: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAY 240
Query: 240 EERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI 279
E + WH+ CF+CKKCS++L + F+ ++ + CPDC K +
Sbjct: 241 EGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKKL 280
>gi|228480211 four and a half LIM domains 1 isoform 1 [Homo sapiens]
Length = 323
Score = 286 bits (731), Expect = 2e-77
Identities = 116/230 (50%), Positives = 162/230 (70%)
Query: 1 MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60
M E+FDCH+C + L GKKY+ ++ C+ CF+ ANTC EC KPIG D K++ YK+R
Sbjct: 1 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
Query: 61 WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
WH+ CF C++C + L ++ F AK++++LC C + E S KC+ C K I+ G + +EYKG+
Sbjct: 61 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
Query: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180
WH+ CF C C+Q IGT SF PK +CV C+E + A CV+C K IT+GG+TY++QP
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180
Query: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISG 230
WH +CFVC C K+L+GQRFTA +D YC++C+ + AKKCAGC NPI+G
Sbjct: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 230
Score = 162 bits (409), Expect = 4e-40
Identities = 71/215 (33%), Positives = 111/215 (51%), Gaps = 6/215 (2%)
Query: 66 FHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHET 125
F C CR+ L K + K+ C C+ ++ C EC+K I ++++ YK WH+T
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
Query: 126 CFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTG--GVTYREQPWHK 183
CF C +C P+ ++F+ KDN+ C C ++ + +C C K I G V Y+ WHK
Sbjct: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124
Query: 184 ECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFEERQ 243
+CF C+ C++ + F + + YC+ C +AK C C I+ G I+++++
Sbjct: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGG----ITYQDQP 180
Query: 244 WHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKD 278
WH DCF C CS L G+ F D C DC K+
Sbjct: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKN 215
>gi|228480221 four and a half LIM domains 1 isoform 4 [Homo sapiens]
Length = 194
Score = 193 bits (491), Expect = 1e-49
Identities = 79/174 (45%), Positives = 113/174 (64%)
Query: 1 MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60
M E+FDCH+C + L GKKY+ ++ C+ CF+ ANTC EC KPIG D K++ YK+R
Sbjct: 1 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
Query: 61 WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
WH+ CF C++C + L ++ F AK++++LC C + E S KC+ C K I+ G + +EYKG+
Sbjct: 61 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
Query: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGV 174
WH+ CF C C+Q IGT SF PK +CV C+E + A CV+C K + V
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKGLVKAPV 174
Score = 125 bits (313), Expect = 5e-29
Identities = 52/161 (32%), Positives = 84/161 (52%), Gaps = 2/161 (1%)
Query: 66 FHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHET 125
F C CR+ L K + K+ C C+ ++ C EC+K I ++++ YK WH+T
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
Query: 126 CFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTG--GVTYREQPWHK 183
CF C +C P+ ++F+ KDN+ C C ++ + +C C K I G V Y+ WHK
Sbjct: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124
Query: 184 ECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGC 224
+CF C+ C++ + F + + YC+ C +AK C C
Sbjct: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKC 165
Score = 110 bits (274), Expect = 2e-24
Identities = 49/151 (32%), Positives = 74/151 (49%), Gaps = 4/151 (2%)
Query: 127 FICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGG--VTYREQPWHKE 184
F CH C+ P+ K ++ KD + C+ C++K A CV+C+KPI V Y+ + WH
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
Query: 185 CFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFEERQW 244
CF C C L+ + F A+D+ C C + KC GC I + G + + ++ W
Sbjct: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI--VAGDQNVEYKGTVW 122
Query: 245 HNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275
H DCF C C + F + +D C C
Sbjct: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTC 153
Score = 69.7 bits (169), Expect = 3e-12
Identities = 32/92 (34%), Positives = 44/92 (47%), Gaps = 2/92 (2%)
Query: 184 ECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFEERQ 243
E F C CR L G+++ +D CL CF A C C PI +K + ++ R
Sbjct: 3 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIG--ADSKEVHYKNRF 60
Query: 244 WHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275
WH+ CF C KC L F+ + + ILC C
Sbjct: 61 WHDTCFRCAKCLHPLANETFVAKDNKILCNKC 92
>gi|170932518 paxillin isoform 3 [Homo sapiens]
Length = 424
Score = 137 bits (344), Expect = 1e-32
Identities = 71/215 (33%), Positives = 102/215 (47%), Gaps = 4/215 (1%)
Query: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
E F C HC E + + + R+ PYC + LF+ C C PI D K ++ DR WH
Sbjct: 213 EHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPI-LD-KVVTALDRTWH 270
Query: 63 EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
F C+QC + F K+ + C Y + ++ KC C + I+ + + W
Sbjct: 271 PEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENY--ISALNTLW 328
Query: 123 HETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQPWH 182
H CF+C C P SF D Q +C Y ++ C C+KPIT +T + +H
Sbjct: 329 HPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFH 388
Query: 183 KECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLY 217
E FVC C KQL+ F ++D YC NCF L+
Sbjct: 389 PEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 423
Score = 112 bits (281), Expect = 3e-25
Identities = 61/191 (31%), Positives = 83/191 (43%), Gaps = 18/191 (9%)
Query: 101 CQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAM 160
C CKK I + + G +WH F+C CQ+ IG+++F +D Q +C Y +
Sbjct: 191 CGACKKPI--AGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSP 248
Query: 161 QCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKK 220
+C C PI VT ++ WH E F C C + F +D AYC + D++A K
Sbjct: 249 RCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPK 308
Query: 221 CAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLT------------ERD 268
C GC I YIS WH +CF C++C V F ER
Sbjct: 309 CGGCARAIL----ENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERR 364
Query: 269 DILCPDCGKDI 279
LC C K I
Sbjct: 365 GSLCSGCQKPI 375
Score = 106 bits (265), Expect = 2e-23
Identities = 63/242 (26%), Positives = 99/242 (40%), Gaps = 8/242 (3%)
Query: 34 TLFANTCEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCY 93
T+ C C KPI ++ + WH F C+ C+ + + F ++ Q C Y
Sbjct: 185 TVAKGVCGACKKPIAGQV--VTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDY 242
Query: 94 SNEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPC 153
N +S +C C I+ + + +WH F C +C G + F KD + +C
Sbjct: 243 HNLFSPRCYYCNGPILD--KVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKD 300
Query: 154 YEKQHAMQCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCF 213
Y A +C C + I ++ WH ECFVC C F D YC +
Sbjct: 301 YFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHY 360
Query: 214 CDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCP 273
+ C+GC PI+G + I+ +++H + F C C L F + D C
Sbjct: 361 HERRGSLCSGCQKPITG----RCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQ 416
Query: 274 DC 275
+C
Sbjct: 417 NC 418
>gi|170932516 paxillin isoform 2 [Homo sapiens]
Length = 557
Score = 137 bits (344), Expect = 1e-32
Identities = 71/215 (33%), Positives = 102/215 (47%), Gaps = 4/215 (1%)
Query: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
E F C HC E + + + R+ PYC + LF+ C C PI D K ++ DR WH
Sbjct: 346 EHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPI-LD-KVVTALDRTWH 403
Query: 63 EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
F C+QC + F K+ + C Y + ++ KC C + I+ + + W
Sbjct: 404 PEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENY--ISALNTLW 461
Query: 123 HETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQPWH 182
H CF+C C P SF D Q +C Y ++ C C+KPIT +T + +H
Sbjct: 462 HPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFH 521
Query: 183 KECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLY 217
E FVC C KQL+ F ++D YC NCF L+
Sbjct: 522 PEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 556
Score = 112 bits (281), Expect = 3e-25
Identities = 61/191 (31%), Positives = 83/191 (43%), Gaps = 18/191 (9%)
Query: 101 CQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAM 160
C CKK I + + G +WH F+C CQ+ IG+++F +D Q +C Y +
Sbjct: 324 CGACKKPI--AGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSP 381
Query: 161 QCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKK 220
+C C PI VT ++ WH E F C C + F +D AYC + D++A K
Sbjct: 382 RCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPK 441
Query: 221 CAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLT------------ERD 268
C GC I YIS WH +CF C++C V F ER
Sbjct: 442 CGGCARAIL----ENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERR 497
Query: 269 DILCPDCGKDI 279
LC C K I
Sbjct: 498 GSLCSGCQKPI 508
Score = 106 bits (265), Expect = 2e-23
Identities = 63/242 (26%), Positives = 99/242 (40%), Gaps = 8/242 (3%)
Query: 34 TLFANTCEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCY 93
T+ C C KPI ++ + WH F C+ C+ + + F ++ Q C Y
Sbjct: 318 TVAKGVCGACKKPIAGQV--VTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDY 375
Query: 94 SNEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPC 153
N +S +C C I+ + + +WH F C +C G + F KD + +C
Sbjct: 376 HNLFSPRCYYCNGPILD--KVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKD 433
Query: 154 YEKQHAMQCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCF 213
Y A +C C + I ++ WH ECFVC C F D YC +
Sbjct: 434 YFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHY 493
Query: 214 CDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCP 273
+ C+GC PI+G + I+ +++H + F C C L F + D C
Sbjct: 494 HERRGSLCSGCQKPITG----RCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQ 549
Query: 274 DC 275
+C
Sbjct: 550 NC 551
>gi|170932514 paxillin isoform 1 [Homo sapiens]
Length = 591
Score = 137 bits (344), Expect = 1e-32
Identities = 71/215 (33%), Positives = 102/215 (47%), Gaps = 4/215 (1%)
Query: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
E F C HC E + + + R+ PYC + LF+ C C PI D K ++ DR WH
Sbjct: 380 EHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPI-LD-KVVTALDRTWH 437
Query: 63 EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
F C+QC + F K+ + C Y + ++ KC C + I+ + + W
Sbjct: 438 PEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENY--ISALNTLW 495
Query: 123 HETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQPWH 182
H CF+C C P SF D Q +C Y ++ C C+KPIT +T + +H
Sbjct: 496 HPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFH 555
Query: 183 KECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLY 217
E FVC C KQL+ F ++D YC NCF L+
Sbjct: 556 PEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 590
Score = 112 bits (281), Expect = 3e-25
Identities = 61/191 (31%), Positives = 83/191 (43%), Gaps = 18/191 (9%)
Query: 101 CQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAM 160
C CKK I + + G +WH F+C CQ+ IG+++F +D Q +C Y +
Sbjct: 358 CGACKKPI--AGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSP 415
Query: 161 QCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKK 220
+C C PI VT ++ WH E F C C + F +D AYC + D++A K
Sbjct: 416 RCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPK 475
Query: 221 CAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLT------------ERD 268
C GC I YIS WH +CF C++C V F ER
Sbjct: 476 CGGCARAIL----ENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERR 531
Query: 269 DILCPDCGKDI 279
LC C K I
Sbjct: 532 GSLCSGCQKPI 542
Score = 106 bits (265), Expect = 2e-23
Identities = 63/242 (26%), Positives = 99/242 (40%), Gaps = 8/242 (3%)
Query: 34 TLFANTCEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCY 93
T+ C C KPI ++ + WH F C+ C+ + + F ++ Q C Y
Sbjct: 352 TVAKGVCGACKKPIAGQV--VTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDY 409
Query: 94 SNEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPC 153
N +S +C C I+ + + +WH F C +C G + F KD + +C
Sbjct: 410 HNLFSPRCYYCNGPILD--KVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKD 467
Query: 154 YEKQHAMQCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCF 213
Y A +C C + I ++ WH ECFVC C F D YC +
Sbjct: 468 YFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHY 527
Query: 214 CDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCP 273
+ C+GC PI+G + I+ +++H + F C C L F + D C
Sbjct: 528 HERRGSLCSGCQKPITG----RCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQ 583
Query: 274 DC 275
+C
Sbjct: 584 NC 585
>gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo
sapiens]
Length = 325
Score = 120 bits (300), Expect = 2e-27
Identities = 77/278 (27%), Positives = 113/278 (40%), Gaps = 16/278 (5%)
Query: 5 FDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWHEA 64
F C C + + E YC F+ LFA C +CG+ I + + + WH
Sbjct: 36 FVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFI--IGRVIKAMNNSWHPE 93
Query: 65 CFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSK-----CQECKKTIMPGTRKMEYKG 119
CF C C+ L D F + LC C++ E + CQ+C I + + +K
Sbjct: 94 CFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAII--DEQPLIFKN 151
Query: 120 SSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQ 179
+H F C C + + T + +C+PC++K C C++PI V +
Sbjct: 152 DPYHPDHFNCANCGKEL-TADARELKGELYCLPCHDKMGVPICGACRRPIEGRVVNAMGK 210
Query: 180 PWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISF 239
WH E FVC C K G R R AYC + L+ C C I G +S
Sbjct: 211 QWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVCFHCNRVIEG----DVVSA 266
Query: 240 EERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGK 277
+ W +CF C C+ L + E D + P C K
Sbjct: 267 LNKAWCVNCFACSTCNTKLTLKNKFVEFD--MKPVCKK 302
Score = 108 bits (269), Expect = 7e-24
Identities = 60/231 (25%), Positives = 101/231 (43%), Gaps = 12/231 (5%)
Query: 35 LFANTCEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYS 94
L + TCE C K ++ +HE CF C+QC + F E + C +
Sbjct: 5 LASATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQ 64
Query: 95 NEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCY 154
++ C +C + I+ R ++ +SWH CF C CQ+ + F+ ++ C PC+
Sbjct: 65 MLFAPCCHQCGEFII--GRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCH 122
Query: 155 EKQHAMQ-----CVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYC 209
++ A C +C I + ++ P+H + F C C K+L+ + + YC
Sbjct: 123 NREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADARELKGEL-YC 181
Query: 210 LNCFCDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVG 260
L C + C C PI G + ++ +QWH + F C KC +G
Sbjct: 182 LPCHDKMGVPICGACRRPIEG----RVVNAMGKQWHVEHFVCAKCEKPFLG 228
Score = 48.5 bits (114), Expect = 6e-06
Identities = 27/92 (29%), Positives = 40/92 (43%), Gaps = 3/92 (3%)
Query: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
E F C C + G ++ R+ YC + LF + C C + I D +S ++ W
Sbjct: 215 EHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVCFHCNRVIEGDV--VSALNKAWC 272
Query: 63 EACFHCSQCRNSLVDK-PFAAKEDQLLCTDCY 93
CF CS C L K F + + +C CY
Sbjct: 273 VNCFACSTCNTKLTLKNKFVEFDMKPVCKKCY 304
>gi|238859658 LIM and senescent cell antigen-like domains 2 isoform
1 [Homo sapiens]
Length = 363
Score = 117 bits (293), Expect = 1e-26
Identities = 72/269 (26%), Positives = 111/269 (41%), Gaps = 14/269 (5%)
Query: 5 FDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWHEA 64
F C C + E YC F+ LFA C CG+ I + + + +WH
Sbjct: 63 FVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFI--IGRVIKAMNNNWHPG 120
Query: 65 CFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSK-----CQECKKTIMPGTRKMEYKG 119
CF C C L D F + LC C++ E + CQ C I + + ++
Sbjct: 121 CFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVI--DEQPLMFRS 178
Query: 120 SSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQ 179
++H F C C + + ++ K + +C+PC++K C C++PI V +
Sbjct: 179 DAYHPDHFNCTHCGKELTAEARELK-GELYCLPCHDKMGVPICGACRRPIEGRVVNALGK 237
Query: 180 PWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISF 239
WH E FVC C K G R + AYC + L+ C C++ I G +S
Sbjct: 238 QWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEG----DVVSA 293
Query: 240 EERQWHNDCFNCKKCSLSLVGRGFLTERD 268
+ W CF+C C+ L + E D
Sbjct: 294 LNKAWCVSCFSCSTCNSKLTLKNKFVEFD 322
Score = 98.2 bits (243), Expect = 7e-21
Identities = 55/226 (24%), Positives = 96/226 (42%), Gaps = 12/226 (5%)
Query: 40 CEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSS 99
C+ C + ++ +HE CF C+QC + F E + C + ++
Sbjct: 37 CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAP 96
Query: 100 KCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHA 159
C C + I+ R ++ ++WH CF C C + F+ ++ C PC+ ++ A
Sbjct: 97 CCGSCGEFII--GRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKA 154
Query: 160 MQ-----CVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFC 214
C +C I + +R +H + F CT C K+L+ + + + YCL C
Sbjct: 155 KGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGEL-YCLPCHD 213
Query: 215 DLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVG 260
+ C C PI G + ++ +QWH + F C KC +G
Sbjct: 214 KMGVPICGACRRPIEG----RVVNALGKQWHVEHFVCAKCEKPFLG 255
Score = 66.6 bits (161), Expect = 2e-11
Identities = 38/155 (24%), Positives = 65/155 (41%), Gaps = 6/155 (3%)
Query: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
+ F+C HC + L + L+ E YC+ C + + C C +PI + + ++ + WH
Sbjct: 184 DHFNCTHCGKELTAEARELKGEL-YCLPCHDKMGVPICGACRRPI--EGRVVNALGKQWH 240
Query: 63 EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
F C++C + K+ C Y+ + C C I + +W
Sbjct: 241 VEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDV--VSALNKAW 298
Query: 123 HETCFICHRCQQPIGTKS-FIPKDNQNFCVPCYEK 156
+CF C C + K+ F+ D + C CYEK
Sbjct: 299 CVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 333
Score = 55.8 bits (133), Expect = 4e-08
Identities = 29/95 (30%), Positives = 39/95 (41%), Gaps = 4/95 (4%)
Query: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFE 240
+H+ CFVC C + F + YC + F L+A C C I G + I
Sbjct: 58 YHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIG----RVIKAM 113
Query: 241 ERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275
WH CF C+ C + L GF+ LC C
Sbjct: 114 NNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPC 148
Score = 48.9 bits (115), Expect = 5e-06
Identities = 31/119 (26%), Positives = 50/119 (42%), Gaps = 3/119 (2%)
Query: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
E F C C + G ++ ++ YC + LF + C C I D +S ++ W
Sbjct: 242 EHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDV--VSALNKAWC 299
Query: 63 EACFHCSQCRNSLVDK-PFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
+CF CS C + L K F + + +C CY + KK +RK + K +
Sbjct: 300 VSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKFPLELKKRLKKLSELTSRKAQPKAT 358
>gi|238776788 LIM and senescent cell antigen-like domains 2 isoform
5 [Homo sapiens]
Length = 336
Score = 117 bits (293), Expect = 1e-26
Identities = 72/269 (26%), Positives = 111/269 (41%), Gaps = 14/269 (5%)
Query: 5 FDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWHEA 64
F C C + E YC F+ LFA C CG+ I + + + +WH
Sbjct: 36 FVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFI--IGRVIKAMNNNWHPG 93
Query: 65 CFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSK-----CQECKKTIMPGTRKMEYKG 119
CF C C L D F + LC C++ E + CQ C I + + ++
Sbjct: 94 CFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVI--DEQPLMFRS 151
Query: 120 SSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQ 179
++H F C C + + ++ K + +C+PC++K C C++PI V +
Sbjct: 152 DAYHPDHFNCTHCGKELTAEARELK-GELYCLPCHDKMGVPICGACRRPIEGRVVNALGK 210
Query: 180 PWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISF 239
WH E FVC C K G R + AYC + L+ C C++ I G +S
Sbjct: 211 QWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEG----DVVSA 266
Query: 240 EERQWHNDCFNCKKCSLSLVGRGFLTERD 268
+ W CF+C C+ L + E D
Sbjct: 267 LNKAWCVSCFSCSTCNSKLTLKNKFVEFD 295
Score = 98.2 bits (243), Expect = 7e-21
Identities = 55/226 (24%), Positives = 96/226 (42%), Gaps = 12/226 (5%)
Query: 40 CEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSS 99
C+ C + ++ +HE CF C+QC + F E + C + ++
Sbjct: 10 CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAP 69
Query: 100 KCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHA 159
C C + I+ R ++ ++WH CF C C + F+ ++ C PC+ ++ A
Sbjct: 70 CCGSCGEFII--GRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKA 127
Query: 160 MQ-----CVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFC 214
C +C I + +R +H + F CT C K+L+ + + + YCL C
Sbjct: 128 KGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGEL-YCLPCHD 186
Query: 215 DLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVG 260
+ C C PI G + ++ +QWH + F C KC +G
Sbjct: 187 KMGVPICGACRRPIEG----RVVNALGKQWHVEHFVCAKCEKPFLG 228
Score = 66.6 bits (161), Expect = 2e-11
Identities = 38/155 (24%), Positives = 65/155 (41%), Gaps = 6/155 (3%)
Query: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
+ F+C HC + L + L+ E YC+ C + + C C +PI + + ++ + WH
Sbjct: 157 DHFNCTHCGKELTAEARELKGEL-YCLPCHDKMGVPICGACRRPI--EGRVVNALGKQWH 213
Query: 63 EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
F C++C + K+ C Y+ + C C I + +W
Sbjct: 214 VEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDV--VSALNKAW 271
Query: 123 HETCFICHRCQQPIGTKS-FIPKDNQNFCVPCYEK 156
+CF C C + K+ F+ D + C CYEK
Sbjct: 272 CVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 306
Score = 55.8 bits (133), Expect = 4e-08
Identities = 29/95 (30%), Positives = 39/95 (41%), Gaps = 4/95 (4%)
Query: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFE 240
+H+ CFVC C + F + YC + F L+A C C I G + I
Sbjct: 31 YHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIG----RVIKAM 86
Query: 241 ERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275
WH CF C+ C + L GF+ LC C
Sbjct: 87 NNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPC 121
Score = 48.9 bits (115), Expect = 5e-06
Identities = 31/119 (26%), Positives = 50/119 (42%), Gaps = 3/119 (2%)
Query: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
E F C C + G ++ ++ YC + LF + C C I D +S ++ W
Sbjct: 215 EHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDV--VSALNKAWC 272
Query: 63 EACFHCSQCRNSLVDK-PFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
+CF CS C + L K F + + +C CY + KK +RK + K +
Sbjct: 273 VSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKFPLELKKRLKKLSELTSRKAQPKAT 331
>gi|238776786 LIM and senescent cell antigen-like domains 2 isoform
3 [Homo sapiens]
Length = 341
Score = 117 bits (293), Expect = 1e-26
Identities = 72/269 (26%), Positives = 111/269 (41%), Gaps = 14/269 (5%)
Query: 5 FDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWHEA 64
F C C + E YC F+ LFA C CG+ I + + + +WH
Sbjct: 41 FVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFI--IGRVIKAMNNNWHPG 98
Query: 65 CFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSK-----CQECKKTIMPGTRKMEYKG 119
CF C C L D F + LC C++ E + CQ C I + + ++
Sbjct: 99 CFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVI--DEQPLMFRS 156
Query: 120 SSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQ 179
++H F C C + + ++ K + +C+PC++K C C++PI V +
Sbjct: 157 DAYHPDHFNCTHCGKELTAEARELK-GELYCLPCHDKMGVPICGACRRPIEGRVVNALGK 215
Query: 180 PWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISF 239
WH E FVC C K G R + AYC + L+ C C++ I G +S
Sbjct: 216 QWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEG----DVVSA 271
Query: 240 EERQWHNDCFNCKKCSLSLVGRGFLTERD 268
+ W CF+C C+ L + E D
Sbjct: 272 LNKAWCVSCFSCSTCNSKLTLKNKFVEFD 300
Score = 98.2 bits (243), Expect = 7e-21
Identities = 55/226 (24%), Positives = 96/226 (42%), Gaps = 12/226 (5%)
Query: 40 CEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSS 99
C+ C + ++ +HE CF C+QC + F E + C + ++
Sbjct: 15 CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAP 74
Query: 100 KCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHA 159
C C + I+ R ++ ++WH CF C C + F+ ++ C PC+ ++ A
Sbjct: 75 CCGSCGEFII--GRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKA 132
Query: 160 MQ-----CVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFC 214
C +C I + +R +H + F CT C K+L+ + + + YCL C
Sbjct: 133 KGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGEL-YCLPCHD 191
Query: 215 DLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVG 260
+ C C PI G + ++ +QWH + F C KC +G
Sbjct: 192 KMGVPICGACRRPIEG----RVVNALGKQWHVEHFVCAKCEKPFLG 233
Score = 66.6 bits (161), Expect = 2e-11
Identities = 38/155 (24%), Positives = 65/155 (41%), Gaps = 6/155 (3%)
Query: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
+ F+C HC + L + L+ E YC+ C + + C C +PI + + ++ + WH
Sbjct: 162 DHFNCTHCGKELTAEARELKGEL-YCLPCHDKMGVPICGACRRPI--EGRVVNALGKQWH 218
Query: 63 EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
F C++C + K+ C Y+ + C C I + +W
Sbjct: 219 VEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDV--VSALNKAW 276
Query: 123 HETCFICHRCQQPIGTKS-FIPKDNQNFCVPCYEK 156
+CF C C + K+ F+ D + C CYEK
Sbjct: 277 CVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 311
Score = 55.8 bits (133), Expect = 4e-08
Identities = 29/95 (30%), Positives = 39/95 (41%), Gaps = 4/95 (4%)
Query: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFE 240
+H+ CFVC C + F + YC + F L+A C C I G + I
Sbjct: 36 YHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIG----RVIKAM 91
Query: 241 ERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275
WH CF C+ C + L GF+ LC C
Sbjct: 92 NNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPC 126
Score = 48.9 bits (115), Expect = 5e-06
Identities = 31/119 (26%), Positives = 50/119 (42%), Gaps = 3/119 (2%)
Query: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
E F C C + G ++ ++ YC + LF + C C I D +S ++ W
Sbjct: 220 EHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDV--VSALNKAWC 277
Query: 63 EACFHCSQCRNSLVDK-PFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
+CF CS C + L K F + + +C CY + KK +RK + K +
Sbjct: 278 VSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKFPLELKKRLKKLSELTSRKAQPKAT 336
>gi|40804748 LIM and senescent cell antigen-like domains 2 isoform 2
[Homo sapiens]
Length = 365
Score = 117 bits (293), Expect = 1e-26
Identities = 72/269 (26%), Positives = 111/269 (41%), Gaps = 14/269 (5%)
Query: 5 FDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWHEA 64
F C C + E YC F+ LFA C CG+ I + + + +WH
Sbjct: 65 FVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFI--IGRVIKAMNNNWHPG 122
Query: 65 CFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSK-----CQECKKTIMPGTRKMEYKG 119
CF C C L D F + LC C++ E + CQ C I + + ++
Sbjct: 123 CFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVI--DEQPLMFRS 180
Query: 120 SSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQ 179
++H F C C + + ++ K + +C+PC++K C C++PI V +
Sbjct: 181 DAYHPDHFNCTHCGKELTAEARELK-GELYCLPCHDKMGVPICGACRRPIEGRVVNALGK 239
Query: 180 PWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISF 239
WH E FVC C K G R + AYC + L+ C C++ I G +S
Sbjct: 240 QWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEG----DVVSA 295
Query: 240 EERQWHNDCFNCKKCSLSLVGRGFLTERD 268
+ W CF+C C+ L + E D
Sbjct: 296 LNKAWCVSCFSCSTCNSKLTLKNKFVEFD 324
Score = 98.2 bits (243), Expect = 7e-21
Identities = 55/226 (24%), Positives = 96/226 (42%), Gaps = 12/226 (5%)
Query: 40 CEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSS 99
C+ C + ++ +HE CF C+QC + F E + C + ++
Sbjct: 39 CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAP 98
Query: 100 KCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHA 159
C C + I+ R ++ ++WH CF C C + F+ ++ C PC+ ++ A
Sbjct: 99 CCGSCGEFII--GRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKA 156
Query: 160 MQ-----CVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFC 214
C +C I + +R +H + F CT C K+L+ + + + YCL C
Sbjct: 157 KGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGEL-YCLPCHD 215
Query: 215 DLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVG 260
+ C C PI G + ++ +QWH + F C KC +G
Sbjct: 216 KMGVPICGACRRPIEG----RVVNALGKQWHVEHFVCAKCEKPFLG 257
Score = 66.6 bits (161), Expect = 2e-11
Identities = 38/155 (24%), Positives = 65/155 (41%), Gaps = 6/155 (3%)
Query: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
+ F+C HC + L + L+ E YC+ C + + C C +PI + + ++ + WH
Sbjct: 186 DHFNCTHCGKELTAEARELKGEL-YCLPCHDKMGVPICGACRRPI--EGRVVNALGKQWH 242
Query: 63 EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
F C++C + K+ C Y+ + C C I + +W
Sbjct: 243 VEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDV--VSALNKAW 300
Query: 123 HETCFICHRCQQPIGTKS-FIPKDNQNFCVPCYEK 156
+CF C C + K+ F+ D + C CYEK
Sbjct: 301 CVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 335
Score = 55.8 bits (133), Expect = 4e-08
Identities = 29/95 (30%), Positives = 39/95 (41%), Gaps = 4/95 (4%)
Query: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFE 240
+H+ CFVC C + F + YC + F L+A C C I G + I
Sbjct: 60 YHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIG----RVIKAM 115
Query: 241 ERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275
WH CF C+ C + L GF+ LC C
Sbjct: 116 NNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPC 150
Score = 48.9 bits (115), Expect = 5e-06
Identities = 31/119 (26%), Positives = 50/119 (42%), Gaps = 3/119 (2%)
Query: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
E F C C + G ++ ++ YC + LF + C C I D +S ++ W
Sbjct: 244 EHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDV--VSALNKAWC 301
Query: 63 EACFHCSQCRNSLVDK-PFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
+CF CS C + L K F + + +C CY + KK +RK + K +
Sbjct: 302 VSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKFPLELKKRLKKLSELTSRKAQPKAT 360
>gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]
Length = 617
Score = 112 bits (280), Expect = 4e-25
Identities = 52/154 (33%), Positives = 74/154 (48%), Gaps = 2/154 (1%)
Query: 119 GSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYRE 178
G SWH F C C+ + F+ + N +C CYE+ A C +C I +
Sbjct: 457 GRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALR 516
Query: 179 QPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYIS 238
Q WH CFVC AC+K F D YC + +L++ KC GC P+ G K+I
Sbjct: 517 QTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVE--AGDKFIE 574
Query: 239 FEERQWHNDCFNCKKCSLSLVGRGFLTERDDILC 272
WH+ CF C C ++L G+ F +++D LC
Sbjct: 575 ALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLC 608
Score = 103 bits (257), Expect = 2e-22
Identities = 47/153 (30%), Positives = 70/153 (45%), Gaps = 4/153 (2%)
Query: 59 RHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYK 118
R WH F C+ C+ SL D F +++ + C CY ++ C +C IM M
Sbjct: 458 RSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIM--GEVMHAL 515
Query: 119 GSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGG--VTY 176
+WH TCF+C C++P G F +D + +C Y + +C C P+ G +
Sbjct: 516 RQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEA 575
Query: 177 REQPWHKECFVCTACRKQLSGQRFTARDDFAYC 209
WH CF+C C L GQ F ++ D C
Sbjct: 576 LGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLC 608
Score = 92.0 bits (227), Expect = 5e-19
Identities = 46/157 (29%), Positives = 74/157 (47%), Gaps = 7/157 (4%)
Query: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
E F C +C SL ++ + + YC C+E FA C +C I + + + WH
Sbjct: 463 EEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEV--MHALRQTWH 520
Query: 63 EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
CF C+ C+ + F ++ + C Y N +S+KC C + G + +E G +W
Sbjct: 521 TTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTW 580
Query: 123 HETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHA 159
H+TCFIC C + + F K ++ C K+HA
Sbjct: 581 HDTCFICAVCHVNLEGQPFYSKKDRPLC-----KKHA 612
Score = 58.2 bits (139), Expect = 8e-09
Identities = 26/88 (29%), Positives = 41/88 (46%)
Query: 2 TERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHW 61
T F C C + + + + PYC + LF+ C C P+ K + W
Sbjct: 521 TTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTW 580
Query: 62 HEACFHCSQCRNSLVDKPFAAKEDQLLC 89
H+ CF C+ C +L +PF +K+D+ LC
Sbjct: 581 HDTCFICAVCHVNLEGQPFYSKKDRPLC 608
Score = 55.1 bits (131), Expect = 7e-08
Identities = 32/117 (27%), Positives = 43/117 (36%), Gaps = 7/117 (5%)
Query: 162 CVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKC 221
C C I + + WH E F C C+ L+ F + YC C+ +A C
Sbjct: 441 CGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLC 500
Query: 222 AGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKD 278
A C I G + + + WH CF C C F E + P C KD
Sbjct: 501 AKCNTKIMG----EVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGE---PYCEKD 550
>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
Length = 727
Score = 112 bits (280), Expect = 4e-25
Identities = 52/154 (33%), Positives = 74/154 (48%), Gaps = 2/154 (1%)
Query: 119 GSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYRE 178
G SWH F C C+ + F+ + N +C CYE+ A C +C I +
Sbjct: 567 GRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALR 626
Query: 179 QPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYIS 238
Q WH CFVC AC+K F D YC + +L++ KC GC P+ G K+I
Sbjct: 627 QTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVE--AGDKFIE 684
Query: 239 FEERQWHNDCFNCKKCSLSLVGRGFLTERDDILC 272
WH+ CF C C ++L G+ F +++D LC
Sbjct: 685 ALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLC 718
Score = 103 bits (257), Expect = 2e-22
Identities = 47/153 (30%), Positives = 70/153 (45%), Gaps = 4/153 (2%)
Query: 59 RHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYK 118
R WH F C+ C+ SL D F +++ + C CY ++ C +C IM M
Sbjct: 568 RSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIM--GEVMHAL 625
Query: 119 GSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGG--VTY 176
+WH TCF+C C++P G F +D + +C Y + +C C P+ G +
Sbjct: 626 RQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEA 685
Query: 177 REQPWHKECFVCTACRKQLSGQRFTARDDFAYC 209
WH CF+C C L GQ F ++ D C
Sbjct: 686 LGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLC 718
Score = 92.0 bits (227), Expect = 5e-19
Identities = 46/157 (29%), Positives = 74/157 (47%), Gaps = 7/157 (4%)
Query: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
E F C +C SL ++ + + YC C+E FA C +C I + + + WH
Sbjct: 573 EEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEV--MHALRQTWH 630
Query: 63 EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
CF C+ C+ + F ++ + C Y N +S+KC C + G + +E G +W
Sbjct: 631 TTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTW 690
Query: 123 HETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHA 159
H+TCFIC C + + F K ++ C K+HA
Sbjct: 691 HDTCFICAVCHVNLEGQPFYSKKDRPLC-----KKHA 722
Score = 58.2 bits (139), Expect = 8e-09
Identities = 26/88 (29%), Positives = 41/88 (46%)
Query: 2 TERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHW 61
T F C C + + + + PYC + LF+ C C P+ K + W
Sbjct: 631 TTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTW 690
Query: 62 HEACFHCSQCRNSLVDKPFAAKEDQLLC 89
H+ CF C+ C +L +PF +K+D+ LC
Sbjct: 691 HDTCFICAVCHVNLEGQPFYSKKDRPLC 718
Score = 55.1 bits (131), Expect = 7e-08
Identities = 32/117 (27%), Positives = 43/117 (36%), Gaps = 7/117 (5%)
Query: 162 CVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKC 221
C C I + + WH E F C C+ L+ F + YC C+ +A C
Sbjct: 551 CGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLC 610
Query: 222 AGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKD 278
A C I G + + + WH CF C C F E + P C KD
Sbjct: 611 AKCNTKIMG----EVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGE---PYCEKD 660
>gi|221316659 leupaxin isoform 1 [Homo sapiens]
Length = 391
Score = 112 bits (279), Expect = 5e-25
Identities = 65/215 (30%), Positives = 92/215 (42%), Gaps = 4/215 (1%)
Query: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
E F C HC E + + R YC + LF+ C C PI D K L+ ++ WH
Sbjct: 179 EHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPI-LD-KVLTAMNQTWH 236
Query: 63 EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
F CS C + F K+ + C + +S KC C + ++ + + W
Sbjct: 237 PEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVLENY--LSAMDTVW 294
Query: 123 HETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQPWH 182
H CF+C C T SF D + FC Y + C C +PIT ++ +H
Sbjct: 295 HPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITGRCISAMGYKFH 354
Query: 183 KECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLY 217
E FVC C QLS F ++D YC CF L+
Sbjct: 355 PEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 389
Score = 105 bits (262), Expect = 4e-23
Identities = 61/236 (25%), Positives = 94/236 (39%), Gaps = 8/236 (3%)
Query: 40 CEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSS 99
C C KPI K + + WH F C+ C+ + PF + C + Y +S
Sbjct: 157 CASCQKPIAG--KVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSP 214
Query: 100 KCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHA 159
+C C I+ + + +WH F C C + G + F KD + +C + +
Sbjct: 215 RCAYCAAPIL--DKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFS 272
Query: 160 MQCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAK 219
+C C +P+ ++ + WH ECFVC C S F D +C +
Sbjct: 273 PKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGT 332
Query: 220 KCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275
C GC PI+G + IS ++H + F C C L F + D C C
Sbjct: 333 LCHGCGQPITG----RCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPC 384
Score = 103 bits (258), Expect = 1e-22
Identities = 57/191 (29%), Positives = 82/191 (42%), Gaps = 18/191 (9%)
Query: 101 CQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAM 160
C C+K I + + G SWH F+C C++ IG+ F + +C Y + +
Sbjct: 157 CASCQKPI--AGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSP 214
Query: 161 QCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKK 220
+C C PI +T Q WH E F C+ C + + F +D YC F +++ K
Sbjct: 215 RCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPK 274
Query: 221 CAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLS--------LVGRGFLT----ERD 268
C GC P+ Y+S + WH +CF C C S L GR F R
Sbjct: 275 CGGCNRPVL----ENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRR 330
Query: 269 DILCPDCGKDI 279
LC CG+ I
Sbjct: 331 GTLCHGCGQPI 341
>gi|4758670 leupaxin isoform 2 [Homo sapiens]
Length = 386
Score = 112 bits (279), Expect = 5e-25
Identities = 65/215 (30%), Positives = 92/215 (42%), Gaps = 4/215 (1%)
Query: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
E F C HC E + + R YC + LF+ C C PI D K L+ ++ WH
Sbjct: 174 EHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPI-LD-KVLTAMNQTWH 231
Query: 63 EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
F CS C + F K+ + C + +S KC C + ++ + + W
Sbjct: 232 PEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVLENY--LSAMDTVW 289
Query: 123 HETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQPWH 182
H CF+C C T SF D + FC Y + C C +PIT ++ +H
Sbjct: 290 HPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITGRCISAMGYKFH 349
Query: 183 KECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLY 217
E FVC C QLS F ++D YC CF L+
Sbjct: 350 PEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 384
Score = 105 bits (262), Expect = 4e-23
Identities = 61/236 (25%), Positives = 94/236 (39%), Gaps = 8/236 (3%)
Query: 40 CEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSS 99
C C KPI K + + WH F C+ C+ + PF + C + Y +S
Sbjct: 152 CASCQKPIAG--KVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSP 209
Query: 100 KCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHA 159
+C C I+ + + +WH F C C + G + F KD + +C + +
Sbjct: 210 RCAYCAAPIL--DKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFS 267
Query: 160 MQCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAK 219
+C C +P+ ++ + WH ECFVC C S F D +C +
Sbjct: 268 PKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGT 327
Query: 220 KCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275
C GC PI+G + IS ++H + F C C L F + D C C
Sbjct: 328 LCHGCGQPITG----RCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPC 379
Score = 103 bits (258), Expect = 1e-22
Identities = 57/191 (29%), Positives = 82/191 (42%), Gaps = 18/191 (9%)
Query: 101 CQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAM 160
C C+K I + + G SWH F+C C++ IG+ F + +C Y + +
Sbjct: 152 CASCQKPI--AGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSP 209
Query: 161 QCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKK 220
+C C PI +T Q WH E F C+ C + + F +D YC F +++ K
Sbjct: 210 RCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPK 269
Query: 221 CAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLS--------LVGRGFLT----ERD 268
C GC P+ Y+S + WH +CF C C S L GR F R
Sbjct: 270 CGGCNRPVL----ENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRR 325
Query: 269 DILCPDCGKDI 279
LC CG+ I
Sbjct: 326 GTLCHGCGQPI 336
>gi|109638745 transforming growth factor beta 1 induced transcript 1
isoform 1 [Homo sapiens]
Length = 461
Score = 112 bits (279), Expect = 5e-25
Identities = 65/236 (27%), Positives = 96/236 (40%), Gaps = 8/236 (3%)
Query: 40 CEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSS 99
C C KPI ++ R WH F C C +L F K+ C +CY +S
Sbjct: 228 CGSCNKPIAGQV--VTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSP 285
Query: 100 KCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHA 159
+C C + I + + G+ WH F C C +P G + F ++ + +C + + A
Sbjct: 286 RCGFCNQPIRH--KMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFA 343
Query: 160 MQCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAK 219
+C C+ PI ++ WH +CFVC C SG F + C N F
Sbjct: 344 PRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGS 403
Query: 220 KCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275
CA C P++G + +S R++H D F C C L F C C
Sbjct: 404 LCATCGLPVTG----RCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPC 455
Score = 108 bits (269), Expect = 7e-24
Identities = 57/215 (26%), Positives = 93/215 (43%), Gaps = 4/215 (1%)
Query: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
E F C C+ +L G + ++ +P+C C+ F+ C C +PI K ++ HWH
Sbjct: 250 EHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIRH--KMVTALGTHWH 307
Query: 63 EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
F C C D+ F +E + C + ++ +CQ C+ I+ + + W
Sbjct: 308 PEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPILDNY--ISALSALW 365
Query: 123 HETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQPWH 182
H CF+C C P SF + + C + + C C P+T V+ + +H
Sbjct: 366 HPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTGRCVSALGRRFH 425
Query: 183 KECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLY 217
+ F CT C + L+ F R YC CF L+
Sbjct: 426 PDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLF 460
Score = 35.0 bits (79), Expect = 0.073
Identities = 22/103 (21%), Positives = 36/103 (34%), Gaps = 30/103 (29%)
Query: 187 VCTACRKQLSGQRFTA--------------------------RDDFAYCLNCFCDLYAKK 220
+C +C K ++GQ TA +D +C C+ + ++ +
Sbjct: 227 LCGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPR 286
Query: 221 CAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGF 263
C C PI K ++ WH + F C C GF
Sbjct: 287 CGFCNQPIR----HKMVTALGTHWHPEHFCCVSCGEPFGDEGF 325
>gi|21361591 transforming growth factor beta 1 induced transcript 1
isoform 2 [Homo sapiens]
Length = 444
Score = 112 bits (279), Expect = 5e-25
Identities = 65/236 (27%), Positives = 96/236 (40%), Gaps = 8/236 (3%)
Query: 40 CEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSS 99
C C KPI ++ R WH F C C +L F K+ C +CY +S
Sbjct: 211 CGSCNKPIAGQV--VTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSP 268
Query: 100 KCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHA 159
+C C + I + + G+ WH F C C +P G + F ++ + +C + + A
Sbjct: 269 RCGFCNQPIRH--KMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFA 326
Query: 160 MQCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAK 219
+C C+ PI ++ WH +CFVC C SG F + C N F
Sbjct: 327 PRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGS 386
Query: 220 KCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275
CA C P++G + +S R++H D F C C L F C C
Sbjct: 387 LCATCGLPVTG----RCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPC 438
Score = 108 bits (269), Expect = 7e-24
Identities = 57/215 (26%), Positives = 93/215 (43%), Gaps = 4/215 (1%)
Query: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
E F C C+ +L G + ++ +P+C C+ F+ C C +PI K ++ HWH
Sbjct: 233 EHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIRH--KMVTALGTHWH 290
Query: 63 EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
F C C D+ F +E + C + ++ +CQ C+ I+ + + W
Sbjct: 291 PEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPILDNY--ISALSALW 348
Query: 123 HETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQPWH 182
H CF+C C P SF + + C + + C C P+T V+ + +H
Sbjct: 349 HPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTGRCVSALGRRFH 408
Query: 183 KECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLY 217
+ F CT C + L+ F R YC CF L+
Sbjct: 409 PDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLF 443
Score = 35.0 bits (79), Expect = 0.073
Identities = 22/103 (21%), Positives = 36/103 (34%), Gaps = 30/103 (29%)
Query: 187 VCTACRKQLSGQRFTA--------------------------RDDFAYCLNCFCDLYAKK 220
+C +C K ++GQ TA +D +C C+ + ++ +
Sbjct: 210 LCGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPR 269
Query: 221 CAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGF 263
C C PI K ++ WH + F C C GF
Sbjct: 270 CGFCNQPIR----HKMVTALGTHWHPEHFCCVSCGEPFGDEGF 308
>gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens]
Length = 423
Score = 109 bits (272), Expect = 3e-24
Identities = 52/179 (29%), Positives = 86/179 (48%), Gaps = 4/179 (2%)
Query: 94 SNEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPC 153
+N + C +C K I R + G ++H F+C +C + + F + FC PC
Sbjct: 241 NNGKTPVCHQCHKVIRG--RYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPC 298
Query: 154 YEKQHAMQCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCF 213
Y+ ++A C +CKK IT + + WH CF C AC+ + + F + YC +
Sbjct: 299 YDVRYAPSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDY 358
Query: 214 CDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILC 272
++ KC GC I G +++ WH+ CF C C ++L G+ F +++D LC
Sbjct: 359 EKMFGTKCHGCDFKID--AGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLC 415
Score = 90.5 bits (223), Expect = 1e-18
Identities = 52/172 (30%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 40 CEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSS 99
C +C K I + L +H F CSQC L + F ++ + C CY Y+
Sbjct: 248 CHQCHKVIRG--RYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAP 305
Query: 100 KCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHA 159
C +CKK I M +WH CF C C+ PI ++F ++ +C YEK
Sbjct: 306 SCAKCKKKIT--GEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFG 363
Query: 160 MQCVQCKKPITTGG--VTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYC 209
+C C I G + WH CFVC C+ L G+ F ++ D C
Sbjct: 364 TKCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLC 415
Score = 88.6 bits (218), Expect = 6e-18
Identities = 47/161 (29%), Positives = 74/161 (45%), Gaps = 7/161 (4%)
Query: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
E F C C + L + + + +C C++ +A +C +C K I + + WH
Sbjct: 270 EEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPSCAKCKKKITGEI--MHALKMTWH 327
Query: 63 EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
CF C+ C+ + ++ F +E C Y + +KC C I G R +E G SW
Sbjct: 328 VHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKCHGCDFKIDAGDRFLEALGFSW 387
Query: 123 HETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCV 163
H+TCF+C CQ + K+F K ++ C K HA V
Sbjct: 388 HDTCFVCAICQINLEGKTFYSKKDRPLC-----KSHAFSHV 423
Score = 31.6 bits (70), Expect = 0.80
Identities = 17/55 (30%), Positives = 23/55 (41%), Gaps = 4/55 (7%)
Query: 221 CAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275
C C I G +Y+ +H + F C +C L GF E+ I CP C
Sbjct: 248 CHQCHKVIRG----RYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPC 298
>gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens]
Length = 457
Score = 109 bits (272), Expect = 3e-24
Identities = 52/179 (29%), Positives = 86/179 (48%), Gaps = 4/179 (2%)
Query: 94 SNEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPC 153
+N + C +C K I R + G ++H F+C +C + + F + FC PC
Sbjct: 275 NNGKTPVCHQCHKVIRG--RYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPC 332
Query: 154 YEKQHAMQCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCF 213
Y+ ++A C +CKK IT + + WH CF C AC+ + + F + YC +
Sbjct: 333 YDVRYAPSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDY 392
Query: 214 CDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILC 272
++ KC GC I G +++ WH+ CF C C ++L G+ F +++D LC
Sbjct: 393 EKMFGTKCHGCDFKID--AGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLC 449
Score = 90.5 bits (223), Expect = 1e-18
Identities = 52/172 (30%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 40 CEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSS 99
C +C K I + L +H F CSQC L + F ++ + C CY Y+
Sbjct: 282 CHQCHKVIRG--RYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAP 339
Query: 100 KCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHA 159
C +CKK I M +WH CF C C+ PI ++F ++ +C YEK
Sbjct: 340 SCAKCKKKIT--GEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFG 397
Query: 160 MQCVQCKKPITTGG--VTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYC 209
+C C I G + WH CFVC C+ L G+ F ++ D C
Sbjct: 398 TKCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLC 449
Score = 88.6 bits (218), Expect = 6e-18
Identities = 47/161 (29%), Positives = 74/161 (45%), Gaps = 7/161 (4%)
Query: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
E F C C + L + + + +C C++ +A +C +C K I + + WH
Sbjct: 304 EEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPSCAKCKKKITGEI--MHALKMTWH 361
Query: 63 EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
CF C+ C+ + ++ F +E C Y + +KC C I G R +E G SW
Sbjct: 362 VHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKCHGCDFKIDAGDRFLEALGFSW 421
Query: 123 HETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCV 163
H+TCF+C CQ + K+F K ++ C K HA V
Sbjct: 422 HDTCFVCAICQINLEGKTFYSKKDRPLC-----KSHAFSHV 457
Score = 31.6 bits (70), Expect = 0.80
Identities = 17/55 (30%), Positives = 23/55 (41%), Gaps = 4/55 (7%)
Query: 221 CAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275
C C I G +Y+ +H + F C +C L GF E+ I CP C
Sbjct: 282 CHQCHKVIRG----RYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPC 332
>gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens]
Length = 487
Score = 105 bits (262), Expect = 4e-23
Identities = 51/154 (33%), Positives = 73/154 (47%), Gaps = 2/154 (1%)
Query: 119 GSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYRE 178
G SWH F C C+ + F+ + +C CYEK A +C +C++ I ++ +
Sbjct: 327 GKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISALK 386
Query: 179 QPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYIS 238
Q WH CFVC AC K + F D YC + L+ C GC PI G ++
Sbjct: 387 QTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIE--AGDMFLE 444
Query: 239 FEERQWHNDCFNCKKCSLSLVGRGFLTERDDILC 272
WH+ CF C C SL G+ F +++D LC
Sbjct: 445 ALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLC 478
Score = 94.0 bits (232), Expect = 1e-19
Identities = 44/153 (28%), Positives = 72/153 (47%), Gaps = 4/153 (2%)
Query: 59 RHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYK 118
+ WH F+C+ C+N++ F ++ L C CY ++ +C C++ I+ +
Sbjct: 328 KSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKIL--GEVISAL 385
Query: 119 GSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYRE 178
+WH +CF+C C +PI F +D + +C Y C C+ PI G +
Sbjct: 386 KQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEA 445
Query: 179 --QPWHKECFVCTACRKQLSGQRFTARDDFAYC 209
WH CFVC+ C + L GQ F ++ D C
Sbjct: 446 LGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLC 478
Score = 87.0 bits (214), Expect = 2e-17
Identities = 43/157 (27%), Positives = 76/157 (48%), Gaps = 7/157 (4%)
Query: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
E F+C HC ++ ++ + + YC +C+E FA C C + I + +S + WH
Sbjct: 333 EEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEV--ISALKQTWH 390
Query: 63 EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
+CF C C + + F ++ + C Y + + C C+ I G +E G +W
Sbjct: 391 VSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEALGYTW 450
Query: 123 HETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHA 159
H+TCF+C C + + ++F K ++ C K+HA
Sbjct: 451 HDTCFVCSVCCESLEGQTFFSKKDKPLC-----KKHA 482
Score = 52.4 bits (124), Expect = 4e-07
Identities = 29/111 (26%), Positives = 43/111 (38%), Gaps = 4/111 (3%)
Query: 162 CVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKC 221
C C + I + + WH E F C C+ ++ F YC C+ +A +C
Sbjct: 311 CAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPEC 370
Query: 222 AGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILC 272
C I G + IS ++ WH CF C C + F E + C
Sbjct: 371 GRCQRKILG----EVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYC 417
Score = 34.7 bits (78), Expect = 0.095
Identities = 18/66 (27%), Positives = 29/66 (43%), Gaps = 13/66 (19%)
Query: 221 CAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILC-------- 272
CA C I G ++ + WH + FNC C ++ GF+ E+ + C
Sbjct: 311 CAHCNQVIRG----PFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFF 366
Query: 273 -PDCGK 277
P+CG+
Sbjct: 367 APECGR 372
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.139 0.494
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,928,616
Number of Sequences: 37866
Number of extensions: 673708
Number of successful extensions: 11354
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 423
Number of HSP's successfully gapped in prelim test: 471
Number of HSP's that attempted gapping in prelim test: 2388
Number of HSP's gapped (non-prelim): 3431
length of query: 279
length of database: 18,247,518
effective HSP length: 101
effective length of query: 178
effective length of database: 14,423,052
effective search space: 2567303256
effective search space used: 2567303256
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.