Search of human proteins with 41399285

Search of human proteins with 41399285

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|41399285 chaperonin [Homo sapiens]
         (573 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|41399285 chaperonin [Homo sapiens]                                1097   0.0  
gi|31542947 chaperonin [Homo sapiens]                                1097   0.0  
gi|5453603 chaperonin containing TCP1, subunit 2 [Homo sapiens]        86   1e-16
gi|38455427 chaperonin containing TCP1, subunit 4 (delta) [Homo ...    82   1e-15
gi|5453607 chaperonin containing TCP1, subunit 7 isoform a [Homo...    77   6e-14
gi|24307939 chaperonin containing TCP1, subunit 5 (epsilon) [Hom...    68   2e-11
gi|4502643 chaperonin containing TCP1, subunit 6A isoform a [Hom...    62   2e-09
gi|58331173 chaperonin containing TCP1, subunit 6B [Homo sapiens]      60   4e-09
gi|63162572 chaperonin containing TCP1, subunit 3 isoform a [Hom...    59   9e-09
gi|57863257 T-complex protein 1 isoform a [Homo sapiens]               58   2e-08
gi|58761486 chaperonin containing TCP1, subunit 3 isoform b [Hom...    56   1e-07
gi|58761484 chaperonin containing TCP1, subunit 3 isoform c [Hom...    45   1e-04
gi|58331171 chaperonin containing TCP1, subunit 6A isoform b [Ho...    45   1e-04
gi|48762932 chaperonin containing TCP1, subunit 8 (theta) [Homo ...    40   0.004
gi|7657253 T-complex protein 1 [Homo sapiens]                          38   0.029
gi|58331185 chaperonin containing TCP1, subunit 7 isoform b [Hom...    37   0.038
gi|4507363 T-cell acute lymphocytic leukemia 1 [Homo sapiens]          35   0.24 
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]             34   0.32 
gi|42794779 myosin 18A isoform b [Homo sapiens]                        34   0.32 
gi|28416946 myosin 18A isoform a [Homo sapiens]                        34   0.32 
gi|100816407 Bardet-Biedl syndrome 10 [Homo sapiens]                   33   0.93 
gi|83716024 kinesin family member 21B [Homo sapiens]                   32   1.2  
gi|4885409 high density lipoprotein binding protein [Homo sapiens]     32   2.1  
gi|42716280 high density lipoprotein binding protein [Homo sapiens]    32   2.1  
gi|156151379 suppressor of IKK epsilon isoform 1 [Homo sapiens]        31   3.5  
gi|156151377 suppressor of IKK epsilon isoform 2 [Homo sapiens]        31   3.5  
gi|33188443 microfilament and actin filament cross-linker protei...    30   6.0  
gi|33188445 microfilament and actin filament cross-linker protei...    30   6.0  
gi|6912482 leucine zipper-EF-hand containing transmembrane prote...    30   7.8  
gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor ...    30   7.8  

>gi|41399285 chaperonin [Homo sapiens]
          Length = 573

 Score = 1097 bits (2837), Expect = 0.0
 Identities = 573/573 (100%), Positives = 573/573 (100%)

Query: 1   MLRLPTVFRQMRPVSRVLAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGR 60
           MLRLPTVFRQMRPVSRVLAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGR
Sbjct: 1   MLRLPTVFRQMRPVSRVLAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGR 60

Query: 61  TVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLA 120
           TVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLA
Sbjct: 61  TVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLA 120

Query: 121 RSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDK 180
           RSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDK
Sbjct: 121 RSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDK 180

Query: 181 EIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQ 240
           EIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQ
Sbjct: 181 EIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQ 240

Query: 241 DAYVLLSEKKISSIQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAV 300
           DAYVLLSEKKISSIQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAV
Sbjct: 241 DAYVLLSEKKISSIQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAV 300

Query: 301 KAPGFGDNRKNQLKDMAIATGGAVFGEEGLTLNLEDVQPHDLGKVGEVIVTKDDAMLLKG 360
           KAPGFGDNRKNQLKDMAIATGGAVFGEEGLTLNLEDVQPHDLGKVGEVIVTKDDAMLLKG
Sbjct: 301 KAPGFGDNRKNQLKDMAIATGGAVFGEEGLTLNLEDVQPHDLGKVGEVIVTKDDAMLLKG 360

Query: 361 KGDKAQIEKRIQEIIEQLDVTTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDR 420
           KGDKAQIEKRIQEIIEQLDVTTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDR
Sbjct: 361 KGDKAQIEKRIQEIIEQLDVTTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDR 420

Query: 421 VTDALNATRAAVEEGIVLGGGCALLRCIPALDSLTPANEDQKIGIEIIKRTLKIPAMTIA 480
           VTDALNATRAAVEEGIVLGGGCALLRCIPALDSLTPANEDQKIGIEIIKRTLKIPAMTIA
Sbjct: 421 VTDALNATRAAVEEGIVLGGGCALLRCIPALDSLTPANEDQKIGIEIIKRTLKIPAMTIA 480

Query: 481 KNAGVEGSLIVEKIMQSSSEVGYDAMAGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLT 540
           KNAGVEGSLIVEKIMQSSSEVGYDAMAGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLT
Sbjct: 481 KNAGVEGSLIVEKIMQSSSEVGYDAMAGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLT 540

Query: 541 TAEVVVTEIPKEEKDPGMGAMGGMGGGMGGGMF 573
           TAEVVVTEIPKEEKDPGMGAMGGMGGGMGGGMF
Sbjct: 541 TAEVVVTEIPKEEKDPGMGAMGGMGGGMGGGMF 573


>gi|31542947 chaperonin [Homo sapiens]
          Length = 573

 Score = 1097 bits (2837), Expect = 0.0
 Identities = 573/573 (100%), Positives = 573/573 (100%)

Query: 1   MLRLPTVFRQMRPVSRVLAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGR 60
           MLRLPTVFRQMRPVSRVLAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGR
Sbjct: 1   MLRLPTVFRQMRPVSRVLAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGR 60

Query: 61  TVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLA 120
           TVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLA
Sbjct: 61  TVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLA 120

Query: 121 RSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDK 180
           RSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDK
Sbjct: 121 RSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDK 180

Query: 181 EIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQ 240
           EIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQ
Sbjct: 181 EIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQ 240

Query: 241 DAYVLLSEKKISSIQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAV 300
           DAYVLLSEKKISSIQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAV
Sbjct: 241 DAYVLLSEKKISSIQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAV 300

Query: 301 KAPGFGDNRKNQLKDMAIATGGAVFGEEGLTLNLEDVQPHDLGKVGEVIVTKDDAMLLKG 360
           KAPGFGDNRKNQLKDMAIATGGAVFGEEGLTLNLEDVQPHDLGKVGEVIVTKDDAMLLKG
Sbjct: 301 KAPGFGDNRKNQLKDMAIATGGAVFGEEGLTLNLEDVQPHDLGKVGEVIVTKDDAMLLKG 360

Query: 361 KGDKAQIEKRIQEIIEQLDVTTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDR 420
           KGDKAQIEKRIQEIIEQLDVTTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDR
Sbjct: 361 KGDKAQIEKRIQEIIEQLDVTTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDR 420

Query: 421 VTDALNATRAAVEEGIVLGGGCALLRCIPALDSLTPANEDQKIGIEIIKRTLKIPAMTIA 480
           VTDALNATRAAVEEGIVLGGGCALLRCIPALDSLTPANEDQKIGIEIIKRTLKIPAMTIA
Sbjct: 421 VTDALNATRAAVEEGIVLGGGCALLRCIPALDSLTPANEDQKIGIEIIKRTLKIPAMTIA 480

Query: 481 KNAGVEGSLIVEKIMQSSSEVGYDAMAGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLT 540
           KNAGVEGSLIVEKIMQSSSEVGYDAMAGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLT
Sbjct: 481 KNAGVEGSLIVEKIMQSSSEVGYDAMAGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLT 540

Query: 541 TAEVVVTEIPKEEKDPGMGAMGGMGGGMGGGMF 573
           TAEVVVTEIPKEEKDPGMGAMGGMGGGMGGGMF
Sbjct: 541 TAEVVVTEIPKEEKDPGMGAMGGMGGGMGGGMF 573


>gi|5453603 chaperonin containing TCP1, subunit 2 [Homo sapiens]
          Length = 535

 Score = 85.5 bits (210), Expect = 1e-16
 Identities = 129/552 (23%), Positives = 230/552 (41%), Gaps = 67/552 (12%)

Query: 31  KFGAD------ARALMLQGVDLLADAVAVTMGPKGRTVIIEQSW--GSPKVTKDGVTVAK 82
           K GAD      AR     G   + D V  T+GPKG   I+  S    S  VT DG T+ K
Sbjct: 13  KAGADEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDASLMVTNDGATILK 72

Query: 83  SIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEI-- 140
           +I +     N  AK++ D++   ++E GDGTT+ TVLA  + +E    I+K  +P  I  
Sbjct: 73  NIGVD----NPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQTIIA 128

Query: 141 --RRGVMLAVDAVIAE-LKKQSKPVTTPEEIAQVATISANGDKEIGNIISDAMKKVGRKG 197
             R     A +A+++  +   S  V   +++  +A  + +   ++     D   K+  + 
Sbjct: 129 GWREATKAAREALLSSAVDHGSDEVKFRQDLMNIAGTTLS--SKLLTHHKDHFTKLAVEA 186

Query: 198 VITVKDGKTLNDELEIIE--GMKFDRGYISPYFINTSK---GQKCEFQDAYVLLSEKKIS 252
           V+ +K    L + + II+  G      Y+   F+   K    Q    ++A +L++   + 
Sbjct: 187 VLRLKGSGNL-EAIHIIKKLGGSLADSYLDEGFLLDKKIGVNQPKRIENAKILIANTGMD 245

Query: 253 SIQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQ 312
           + +  +    +        V   E  + E +   V   LK G+     +   +  N   Q
Sbjct: 246 TDKIKIFGSRV-RVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIY--NYPEQ 302

Query: 313 LKDMAIATGGAVFGEEGLT----LNLEDVQPHDLGKVGEVIVTKDDAMLLKGKGDKAQIE 368
           L           FG  G+      +   V+   L   GE+  T D   L+K    K    
Sbjct: 303 L-----------FGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCK---- 347

Query: 369 KRIQEIIEQLDVTTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNAT 428
                +IE++ +     E + ++     L +   ++  G T  + ++E +  + DAL   
Sbjct: 348 -----LIEEVMIG----EDKLIHFSGVALGEACTIVLRGATQQI-LDEAERSLHDALCVL 397

Query: 429 RAAVEEG-IVLGGGCA---LLRCIPALDSLTPANEDQKIGIEIIKRTLKIPAMTIAKNAG 484
              V++   V GGGC+   +   +  L + TP  E   + +E   + L++    IA NAG
Sbjct: 398 AQTVKDSRTVYGGGCSEMLMAHAVTQLANRTPGKE--AVAMESYAKALRMLPTIIADNAG 455

Query: 485 VEGSLIVEKIMQSSSE----VGYDAMAGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLT 540
            + + +V ++  + SE     G D   G   +M   GI +  +V R  LL AA  A ++ 
Sbjct: 456 YDSADLVAQLRAAHSEGNTTAGLDMREGTIGDMAILGITESFQVKRQVLLSAAEAAEVIL 515

Query: 541 TAEVVVTEIPKE 552
             + ++   P++
Sbjct: 516 RVDNIIKAAPRK 527


>gi|38455427 chaperonin containing TCP1, subunit 4 (delta) [Homo
           sapiens]
          Length = 539

 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 119/539 (22%), Positives = 230/539 (42%), Gaps = 56/539 (10%)

Query: 34  ADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNI 93
           A  R   +     +ADA+  ++GPKG   +I+   G   +T DG T+ K + +       
Sbjct: 31  AQIRFSNISAAKAVADAIRTSLGPKGMDKMIQDGKGDVTITNDGATILKQMQVLHP---- 86

Query: 94  GAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIA 153
            A+++ +++   + EAGDGTT+  ++A S+     + + KG +P  I      A++  I 
Sbjct: 87  AARMLVELSKAQDIEAGDGTTSVVIIAGSLLDSCTKLLQKGIHPTIISESFQKALEKGIE 146

Query: 154 ELKKQSKPV--TTPEEIAQVATISANGD--KEIGNIIS----DAMKKVGRKGVITVKDGK 205
            L   S+PV  +  E +   AT S N     +  +++S    +A+ KV      T  D +
Sbjct: 147 ILTDMSRPVELSDRETLLNSATTSLNSKVVSQYSSLLSPMSVNAVMKVIDPATATSVDLR 206

Query: 206 TLN---------DELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSIQS 256
            +          D+ E++EG+   +   +      ++ +K +       LS  K      
Sbjct: 207 DIKIVKKLGGTIDDCELVEGLVLTQKVSNS---GITRVEKAKIGLIQFCLSAPKTDMDNQ 263

Query: 257 IVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDM 316
           IV + + A   R    ++ E  +   +  LV    K G  V+ +        +K+ L+D 
Sbjct: 264 IVVS-DYAQMDR----VLRE--ERAYILNLVKQIKKTGCNVLLI--------QKSILRD- 307

Query: 317 AIATGGAVFGEEGLTLNLEDVQPHDLGKVGEVIVTKDDAMLLKGKGDKAQIEKRIQEIIE 376
           A++     F  +   + ++D++  D+  + + I TK  A + +   D         E+ E
Sbjct: 308 ALSDLALHFLNKMKIMVIKDIEREDIEFICKTIGTKPVAHIDQFTADML----GSAELAE 363

Query: 377 QLDVTTSEYEKEKLNERLAKLSDGVAV-LKVGGTSDVEVNEKKDRVTDALNATRAAVEE- 434
           ++++  S     KL +     S G  V + V G++ + + E +  + DAL   R  V++ 
Sbjct: 364 EVNLNGS----GKLLKITGCASPGKTVTIVVRGSNKLVIEEAERSIHDALCVIRCLVKKR 419

Query: 435 GIVLGGGCALLRCIPALDSLT-PANEDQKIGIEIIKRTLKIPAMTIAKNAGVEGSLIVEK 493
            ++ GGG   +     L   +   +  +   +      +++   T+A+NAG+     V +
Sbjct: 420 ALIAGGGAPEIELALRLTEYSRTLSGMESYCVRAFADAMEVIPSTLAENAGLNPISTVTE 479

Query: 494 I----MQSSSEVGYDAMAGDFVNMVEKGIIDPTKVVRTAL-LDAAGVASLLTTAEVVVT 547
           +     Q     G +   G   N++E+ ++ P  V  +AL L    V S+L   +VV T
Sbjct: 480 LRNRHAQGEKTAGINVRKGGISNILEELVVQPLLVSVSALTLATETVRSILKIDDVVNT 538


>gi|5453607 chaperonin containing TCP1, subunit 7 isoform a [Homo
           sapiens]
          Length = 543

 Score = 76.6 bits (187), Expect = 6e-14
 Identities = 120/546 (21%), Positives = 214/546 (39%), Gaps = 50/546 (9%)

Query: 41  LQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQD 100
           +    ++A+AV  T+GP+G   +I    G   ++ DG T+ K +D+        AK + D
Sbjct: 26  ISACQVIAEAVRTTLGPRGMDKLIVDGRGKATISNDGATILKLLDVVHP----AAKTLVD 81

Query: 101 VANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSK 160
           +A + + E GDGTT+ T+LA    K+    + +G +P  I R    A    + ++K+ + 
Sbjct: 82  IAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQIIIRAFRTATQLAVNKIKEIAV 141

Query: 161 PVTTPEEIAQVATISANGDKEIGNIISDAMKKVGRKGVITVKDGKTLND---ELEIIEGM 217
            V   +++ Q   +       + + +    K    K V+   D   + D   +L++I   
Sbjct: 142 TVKKADKVEQRKLLEKCAMTALSSKLISQQKAFFAKMVV---DAVMMLDDLLQLKMIGIK 198

Query: 218 KFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKIS----SIQSIVPALEIANAHRKPLVI 273
           K   G +    +      K  F  A   +  KK      ++ ++   L+    + +  V 
Sbjct: 199 KVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKKYHNPKIALLNVELELKAEKDNAEIRVH 258

Query: 274 IAEDVDG--EALSTLVLNRLK----VGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGE 327
             ED     +A   ++ ++L+     G +VV  K P  GD       D  +   G V  E
Sbjct: 259 TVEDYQAIVDAEWNILYDKLEKIHHSGAKVVLSKLP-IGDVATQYFADRDMFCAGRV-PE 316

Query: 328 EGLTLNLEDVQPHDLGKVGEVIVTKDDAMLLKGKGDKAQIEKRIQEIIEQLDVTTSEYEK 387
           E L           +   G  I T  +A+        A +  R Q + E+  +    Y  
Sbjct: 317 EDL--------KRTMMACGGSIQTSVNAL-------SADVLGRCQ-VFEETQIGGERY-- 358

Query: 388 EKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVE-EGIVLGGGCALLR 446
                   K      +L+ G    +E  E+   + DA+   R A++ + +V GGG   + 
Sbjct: 359 -NFFTGCPKAKTCTFILRGGAEQFMEETERS--LHDAIMIVRRAIKNDSVVAGGGAIEME 415

Query: 447 CIPAL-DSLTPANEDQKIGIEIIKRTLKIPAMTIAKNAGVEGSLIVEKI----MQSSSEV 501
               L D        Q++ I    + L+I    +  NAG + + I+ K+     Q  +  
Sbjct: 416 LSKYLRDYSRTIPGKQQLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQGGTWY 475

Query: 502 GYDAMAGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEVVVTEIPKEEKDPGMGAM 561
           G D    D  +  E  + +P  V   AL  A+  A L+ + +  +   P+   D    A 
Sbjct: 476 GVDINNEDIADNFEAFVWEPAMVRINALTAASEAACLIVSVDETIKN-PRSTVDAPTAAG 534

Query: 562 GGMGGG 567
            G G G
Sbjct: 535 RGRGRG 540


>gi|24307939 chaperonin containing TCP1, subunit 5 (epsilon) [Homo
           sapiens]
          Length = 541

 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 107/537 (19%), Positives = 205/537 (38%), Gaps = 107/537 (19%)

Query: 33  GADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKN 92
           G +A    +     +A+ +  ++GP G   ++    G   VT DG T+   +D+  +   
Sbjct: 30  GLEALKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTNDGATILSMMDVDHQI-- 87

Query: 93  IGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVI 152
             AKL+ +++ + ++E GDGTT   VLA ++ +E  + + +G +P+ I  G   A    I
Sbjct: 88  --AKLMVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQAARVAI 145

Query: 153 AELKKQSKPVTTPEEIAQ--VATISANGDKEIGNIISDAMKKVGRKGVITVKDGKTLN-- 208
             L K S  V    +  +  + T       ++ N     M ++    V+TV D +  +  
Sbjct: 146 EHLDKISDSVLVDIKDTEPLIQTAKTTLGSKVVNSCHRQMAEIAVNAVLTVADMERRDVD 205

Query: 209 --------------DELEIIEGMKFDRGYISPYFINTSKGQK-----CEFQ--------- 240
                         ++ ++I+G+  D+ +  P      +  K     C F+         
Sbjct: 206 FELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKPKTKHK 265

Query: 241 ------DAYVLLSEKKISSIQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVG 294
                 + Y  L + +    + ++  ++   A+   L I     D EA   L+ N L   
Sbjct: 266 LDVTSVEDYKALQKYEKEKFEEMIQQIKETGAN---LAICQWGFDDEANHLLLQNNLP-- 320

Query: 295 LQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLTLNLEDVQPHDLGKVGEV----IV 350
               AV+  G       +++ +AIATGG +           ++    LG  G V      
Sbjct: 321 ----AVRWVG-----GPEIELIAIATGGRI------VPRFSELTAEKLGFAGLVQEISFG 365

Query: 351 TKDDAMLLKGKGDKAQIEKRIQEIIEQLDVTTSEYEKEKLNERLAKLSDGVAVLKVGGTS 410
           T  D ML                +IEQ                  K S  V +   GG  
Sbjct: 366 TTKDKML----------------VIEQ-----------------CKNSRAVTIFIRGGNK 392

Query: 411 DVEVNEKKDRVTDALNATRAAVEEG-IVLGGGCALLRCIPAL-DSLTPANEDQKIGIEII 468
            + + E K  + DAL   R  + +  +V GGG A + C  A+          ++  +   
Sbjct: 393 MI-IEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKCPTLEQYAMRAF 451

Query: 469 KRTLKIPAMTIAKNAGVE-----GSLIVEKIMQSSSEVGYDAMAGDFVNMVEKGIID 520
              L++  M +++N+G+        +   ++ + +  +G D +     +M ++ +I+
Sbjct: 452 ADALEVIPMALSENSGMNPIQTMTEVRARQVKEMNPALGIDCLHKGTNDMKQQHVIE 508


>gi|4502643 chaperonin containing TCP1, subunit 6A isoform a [Homo
           sapiens]
          Length = 531

 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 123/571 (21%), Positives = 234/571 (40%), Gaps = 101/571 (17%)

Query: 36  ARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGA 95
           A A+ +     L D +   +GPKG   ++    G  K+TKDG  +   + ++       A
Sbjct: 19  ALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMQIQHPT----A 74

Query: 96  KLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAEL 155
            L+  VA   ++  GDGTT+  ++   + K+    IS+G +P  I  G   A +  +  L
Sbjct: 75  SLIAKVATAQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIITEGFEAAKEKALQFL 134

Query: 156 K--KQSKPVTTPEEIAQVA--TISANGDKEIGNIISD-------AMKKVGRK---GVITV 201
           +  K S+ +   E +  VA  ++      E+ +++++       A+KK        +I +
Sbjct: 135 EEVKVSREMDR-ETLIDVARTSLRTKVHAELADVLTEAVVDSILAIKKQDEPIDLFMIEI 193

Query: 202 KDGKTLND-ELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVL-------LSEKKISS 253
            + K  ++ +  +I G+  D G   P         K   +DAY+L         + +++S
Sbjct: 194 MEMKHKSETDTSLIRGLVLDHGARHP-------DMKKRVEDAYILTCNVSLEYEKTEVNS 246

Query: 254 ---IQSIVPALEIANAHR-------KPLVIIAEDVDGEA-LSTLVLNRLKVG-LQVVAVK 301
               +S     ++  A R       K ++ +   V G++    +V+N+  +    + A+ 
Sbjct: 247 GFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPFSLDALS 306

Query: 302 APGFGDNRKNQLKDM---AIATGGAVFGEEGLTLNLEDVQPHDLGKVGEVIVTKDDAMLL 358
             G    R+ + ++M    +A GG          + +D+ P  LG  G V          
Sbjct: 307 KEGIVALRRAKRRNMERLTLACGGVALN------SFDDLSPDCLGHAGLVY--------- 351

Query: 359 KGKGDKAQIEKRIQEIIEQLDVTTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKK 418
               +    E++   I             EK N   +        L + G +   + + K
Sbjct: 352 ----EYTLGEEKFTFI-------------EKCNNPRS------VTLLIKGPNKHTLTQIK 388

Query: 419 DRVTDALNATRAAVEEG-IVLGGGCALLRCIPALDSLTPANEDQ-KIGIEIIKRTLKIPA 476
           D V D L A + A+++G +V G G   +    AL    P+ + + ++G++     L I  
Sbjct: 389 DAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAEALIKHKPSVKGRAQLGVQAFADALLIIP 448

Query: 477 MTIAKNAGVEGSLIVEKIMQSSSE----VGYDAMAGDFVNMVEKGIIDPTKVVRTALLDA 532
             +A+N+G +    + KI    SE    VG D   G+ +   E G+ D    V+  LL +
Sbjct: 449 KVLAQNSGFDLQETLVKIQAEHSESGQLVGVDLNTGEPMVAAEVGVWD-NYCVKKQLLHS 507

Query: 533 AGVASLLTTAEVVVTEIPKEEKDPGMGAMGG 563
               +++ T  ++V EI +     GM ++ G
Sbjct: 508 ---CTVIATNILLVDEIMR----AGMSSLKG 531


>gi|58331173 chaperonin containing TCP1, subunit 6B [Homo sapiens]
          Length = 530

 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 101/526 (19%), Positives = 210/526 (39%), Gaps = 59/526 (11%)

Query: 47  LADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTN 106
           L D +   +GPKG   ++    G  K+TKDG  +   + ++       A L+  VA   +
Sbjct: 30  LQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLDEMQIQHPT----ASLIAKVATAQD 85

Query: 107 EEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLA-------VDAVIAELKKQS 159
           +  GDGTT+  ++   + K+    IS+G +P  I  G   A       ++ V    + + 
Sbjct: 86  DVTGDGTTSNVLIIGELLKQADLYISEGLHPRIIAEGFEAAKIKALEVLEEVKVTKEMKR 145

Query: 160 KPVTTPEEIAQVATISANGDKEIGNIISDAMKKVGRKG------VITVKDGK-TLNDELE 212
           K +      +    + A     +  ++ D++  V R G      ++ + + K  L  + +
Sbjct: 146 KILLDVARTSLQTKVHAELADVLTEVVVDSVLAVRRPGYPIDLFMVEIMEMKHKLGTDTK 205

Query: 213 IIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSIQSIV-PALEIANAHRKPL 271
           +I+G+  D G   P         K   +DA++L+    +   ++ V        A  K  
Sbjct: 206 LIQGLVLDHGARHP-------DMKKRVEDAFILICNVSLEYEKTEVNSGFFYKTAEEKEK 258

Query: 272 VIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGL- 330
           ++ AE          + +R++   +++ +K      + K          G  V  ++G+ 
Sbjct: 259 LVKAE-------RKFIEDRVQ---KIIDLKDKVCAQSNK----------GFVVINQKGID 298

Query: 331 TLNLEDVQPHDLGKVGEVIVTKDDAMLLKGKGDKAQIEKRIQEIIEQLDVTTSEYEKEKL 390
             +L+ +  H +  +        + + L   G    +       ++ L      YE    
Sbjct: 299 PFSLDSLAKHGIVALRRAKRRNMERLSLACGG--MAVNSFEDLTVDCLGHAGLVYEYTLG 356

Query: 391 NERLAKLSDGV----AVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEG-IVLGGGCALL 445
            E+   + + V      L V G +   + + KD + D L A + A+E+G +V G G   +
Sbjct: 357 EEKFTFIEECVNPCSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAGAIEV 416

Query: 446 RCIPALDSLTPANEDQ-KIGIEIIKRTLKIPAMTIAKNAGVEGSLIVEKI----MQSSSE 500
               AL +   + + + ++G++     L I    +A+NAG +    + K+    ++S   
Sbjct: 417 AMAEALVTYKNSIKGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHVESKQL 476

Query: 501 VGYDAMAGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEVVV 546
           VG D   G+ +   + G+ D   V +  L     +A+ +   + ++
Sbjct: 477 VGVDLNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNILLVDEIM 522


>gi|63162572 chaperonin containing TCP1, subunit 3 isoform a [Homo
           sapiens]
          Length = 545

 Score = 59.3 bits (142), Expect = 9e-09
 Identities = 123/575 (21%), Positives = 225/575 (39%), Gaps = 78/575 (13%)

Query: 12  RPVSRVLAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSP 71
           RPV  VL+ +  R   + V+ G       +     +AD +   +GPK    ++    G  
Sbjct: 5   RPVL-VLSQNTKRESGRKVQSGN------INAAKTIADIIRTCLGPKSMMKMLLDPMGGI 57

Query: 72  KVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKI 131
            +T DG  + + I ++       AK + +++   +EE GDGTT+  +LA  +       +
Sbjct: 58  VMTNDGNAILREIQVQHP----AAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFL 113

Query: 132 SKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISAN-GDKEIG------- 183
            +  +P  +      A+D +I+ LKK S PV   +    +  I+++   K I        
Sbjct: 114 EQQMHPTVVISAYRKALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLAC 173

Query: 184 NIISDAMKKV-----GRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCE 238
           NI  DA+K V     GRK +   K  +       IIE     RG +    +   + ++  
Sbjct: 174 NIALDAVKMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYI 233

Query: 239 FQDAYVLLSEKKISSIQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVV 298
                VLL             +LE      +  + I  + D     T +L   +  +Q +
Sbjct: 234 KNPRIVLLDS-----------SLEYKKGESQTDIEITREED----FTRILQMEEEYIQQL 278

Query: 299 AVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLTLNLEDVQPHDLGKVGEVIVTK----DD 354
                          +D+       V  E+G++    D+  H L +     + +    D+
Sbjct: 279 C--------------EDIIQLKPDVVITEKGIS----DLAQHYLMRANITAIRRVRKTDN 320

Query: 355 AMLLKGKGDKAQIEKRIQEIIEQLDVTTSE--YEKEKL-NERLAKLSD----GVAVLKVG 407
             + +  G  A+I  R +E+ E  DV T     E +K+ +E    ++D        + + 
Sbjct: 321 NRIARACG--ARIVSRPEELRED-DVGTGAGLLEIKKIGDEYFTFITDCKDPKACTILLR 377

Query: 408 GTSDVEVNEKKDRVTDALNATR-AAVEEGIVLGGGCALLRCIPALDSLTPANED-QKIGI 465
           G S   ++E +  + DA+   R   ++  +V GGG + +    AL   + A    ++   
Sbjct: 378 GASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHALTEKSKAMTGVEQWPY 437

Query: 466 EIIKRTLKIPAMTIAKNAGVE-----GSLIVEKIMQSSSEVGYDAMAGDFVNMVEKGIID 520
             + + L++   T+ +N G        SL  +   ++    G +   G  V+M E GI +
Sbjct: 438 RAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGVNGETGTLVDMKELGIWE 497

Query: 521 PTKVVRTALLDAAGVASLLTTAEVVVTEIPKEEKD 555
           P  V       A   A LL   + +V+   K+  D
Sbjct: 498 PLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDD 532


>gi|57863257 T-complex protein 1 isoform a [Homo sapiens]
          Length = 556

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 107/567 (18%), Positives = 222/567 (39%), Gaps = 76/567 (13%)

Query: 29  DVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKD 88
           D   G   R+  +     +A+ V  ++GP G   ++    G   +T DG T+ K ++++ 
Sbjct: 10  DRSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEH 69

Query: 89  KYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAV 148
                 AK++ ++A+  ++E GDGTT+  ++A  + K   E + +  +P  +  G  LA 
Sbjct: 70  P----AAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLAC 125

Query: 149 DAVIAELKKQSKPVTTPEEIAQVATISANGDKEIGNIISDAMKKVGRKGVITVKDGKTLN 208
              +  + +                +  N D+   + + +A K      +I +      N
Sbjct: 126 KEAVRYINE---------------NLIVNTDELGRDCLINAAKTSMSSKIIGINGDFFAN 170

Query: 209 DELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSIQSIV---PALE-IA 264
             ++ +  +K+             +GQ     ++  +L     S ++S++    AL  + 
Sbjct: 171 MVVDAVLAIKY----------TDIRGQPRYPVNSVNILKAHGRSQMESMLISGYALNCVV 220

Query: 265 NAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMA------- 317
            +   P  I+   +     S L   ++K+G+QVV +  P   D  + +  D+        
Sbjct: 221 GSQGMPKRIVNAKIACLDFS-LQKTKMKLGVQVV-ITDPEKLDQIRQRESDITKERIQKI 278

Query: 318 IATGGAVFGEEGLTLNLEDVQPHDLGKVGEV----IVTKDDAMLLKGKGDKAQIEKRIQE 373
           +ATG  V    G    ++D+      + G +    ++ +D   + K  G          E
Sbjct: 279 LATGANVILTTG---GIDDMCLKYFVEAGAMAVRRVLKRDLKRIAKASGATILSTLANLE 335

Query: 374 IIEQLDVTTSEYEKEKLNERLAKLSDGVAVLK-----------VGGTSDVEVNEKKDRVT 422
             E  +       +E + ER+    D + ++K           + G +D   +E +  + 
Sbjct: 336 GEETFEAAMLGQAEEVVQERIC--DDELILIKNTKARTSASIILRGANDFMCDEMERSLH 393

Query: 423 DALNATRAAVEEGIVLGGGCALLRCIPAL--DSLTPANEDQKIGIEIIKRTLKIPAMTIA 480
           DAL   +  +E   V+ GG A+   +     +  T     +++ I    R+L +   T+A
Sbjct: 394 DALCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLA 453

Query: 481 KNAGVEGSLIVEKIMQSSSE------------VGYDAMAGDFVNMVEKGIIDPTKVVRTA 528
            NA  + + +V K+    +E            +G D   G   +  + G+ +PT V   +
Sbjct: 454 VNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKS 513

Query: 529 LLDAAGVASLLTTAEVVVTEIPKEEKD 555
           L  A   A  +   + ++   P+ + D
Sbjct: 514 LKFATEAAITILRIDDLIKLHPESKDD 540


>gi|58761486 chaperonin containing TCP1, subunit 3 isoform b [Homo
           sapiens]
          Length = 544

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 124/576 (21%), Positives = 227/576 (39%), Gaps = 81/576 (14%)

Query: 12  RPVSRVLAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSP 71
           RPV  VL+ +  R   + V+ G       +     +AD +   +GPK    ++    G  
Sbjct: 5   RPVL-VLSQNTKRESGRKVQSGN------INAAKTIADIIRTCLGPKSMMKMLLDPMGGI 57

Query: 72  KVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIA-KEGFEK 130
            +T DG  + + I ++       AK + +++   +EE GDGTT+  +L   ++  E F  
Sbjct: 58  VMTNDGNAILREIQVQHP----AAKSMIEISRTQDEEVGDGTTSVIILGEMLSVAEHF-- 111

Query: 131 ISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISAN-GDKEIG------ 183
           + +  +P  +      A+D +I+ LKK S PV   +    +  I+++   K I       
Sbjct: 112 LEQQMHPTVVISAYRKALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLA 171

Query: 184 -NIISDAMKKV-----GRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKC 237
            NI  DA+K V     GRK +   K  +       IIE     RG +    +   + ++ 
Sbjct: 172 CNIALDAVKMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRY 231

Query: 238 EFQDAYVLLSEKKISSIQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQV 297
                 VLL             +LE      +  + I  + D     T +L   +  +Q 
Sbjct: 232 IKNPRIVLLDS-----------SLEYKKGESQTDIEITREED----FTRILQMEEEYIQQ 276

Query: 298 VAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLTLNLEDVQPHDLGKVGEVIVTK----D 353
           +               +D+       V  E+G++    D+  H L +     + +    D
Sbjct: 277 LC--------------EDIIQLKPDVVITEKGIS----DLAQHYLMRANITAIRRVRKTD 318

Query: 354 DAMLLKGKGDKAQIEKRIQEIIEQLDVTTSE--YEKEKL-NERLAKLSD----GVAVLKV 406
           +  + +  G  A+I  R +E+ E  DV T     E +K+ +E    ++D        + +
Sbjct: 319 NNRIARACG--ARIVSRPEELRED-DVGTGAGLLEIKKIGDEYFTFITDCKDPKACTILL 375

Query: 407 GGTSDVEVNEKKDRVTDALNATR-AAVEEGIVLGGGCALLRCIPALDSLTPANED-QKIG 464
            G S   ++E +  + DA+   R   ++  +V GGG + +    AL   + A    ++  
Sbjct: 376 RGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHALTEKSKAMTGVEQWP 435

Query: 465 IEIIKRTLKIPAMTIAKNAGVE-----GSLIVEKIMQSSSEVGYDAMAGDFVNMVEKGII 519
              + + L++   T+ +N G        SL  +   ++    G +   G  V+M E GI 
Sbjct: 436 YRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGVNGETGTLVDMKELGIW 495

Query: 520 DPTKVVRTALLDAAGVASLLTTAEVVVTEIPKEEKD 555
           +P  V       A   A LL   + +V+   K+  D
Sbjct: 496 EPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDD 531


>gi|58761484 chaperonin containing TCP1, subunit 3 isoform c [Homo
           sapiens]
          Length = 507

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 106/500 (21%), Positives = 196/500 (39%), Gaps = 67/500 (13%)

Query: 87  KDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVML 146
           K + ++  AK + +++   +EE GDGTT+  +LA  +       + +  +P  +      
Sbjct: 31  KIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVVISAYRK 90

Query: 147 AVDAVIAELKKQSKPVTTPEEIAQVATISAN-GDKEIG-------NIISDAMKKV----- 193
           A+D +I+ LKK S PV   +    +  I+++   K I        NI  DA+K V     
Sbjct: 91  ALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAVKMVQFEEN 150

Query: 194 GRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISS 253
           GRK +   K  +       IIE     RG +    +   + ++       VLL       
Sbjct: 151 GRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDS----- 205

Query: 254 IQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQL 313
                 +LE      +  + I  + D     T +L   +  +Q +               
Sbjct: 206 ------SLEYKKGESQTDIEITREED----FTRILQMEEEYIQQLC-------------- 241

Query: 314 KDMAIATGGAVFGEEGLTLNLEDVQPHDLGKVGEVIVTK----DDAMLLKGKGDKAQIEK 369
           +D+       V  E+G++    D+  H L +     + +    D+  + +  G  A+I  
Sbjct: 242 EDIIQLKPDVVITEKGIS----DLAQHYLMRANITAIRRVRKTDNNRIARACG--ARIVS 295

Query: 370 RIQEIIEQLDVTTSE--YEKEKL-NERLAKLSD----GVAVLKVGGTSDVEVNEKKDRVT 422
           R +E+ E  DV T     E +K+ +E    ++D        + + G S   ++E +  + 
Sbjct: 296 RPEELRED-DVGTGAGLLEIKKIGDEYFTFITDCKDPKACTILLRGASKEILSEVERNLQ 354

Query: 423 DALNATR-AAVEEGIVLGGGCALLRCIPALDSLTPANED-QKIGIEIIKRTLKIPAMTIA 480
           DA+   R   ++  +V GGG + +    AL   + A    ++     + + L++   T+ 
Sbjct: 355 DAMQVCRNVLLDPQLVPGGGASEMAVAHALTEKSKAMTGVEQWPYRAVAQALEVIPRTLI 414

Query: 481 KNAGVE-----GSLIVEKIMQSSSEVGYDAMAGDFVNMVEKGIIDPTKVVRTALLDAAGV 535
           +N G        SL  +   ++    G +   G  V+M E GI +P  V       A   
Sbjct: 415 QNCGASTIRLLTSLRAKHTQENCETWGVNGETGTLVDMKELGIWEPLAVKLQTYKTAVET 474

Query: 536 ASLLTTAEVVVTEIPKEEKD 555
           A LL   + +V+   K+  D
Sbjct: 475 AVLLLRIDDIVSGHKKKGDD 494


>gi|58331171 chaperonin containing TCP1, subunit 6A isoform b [Homo
           sapiens]
          Length = 486

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 110/546 (20%), Positives = 217/546 (39%), Gaps = 96/546 (17%)

Query: 36  ARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGA 95
           A A+ +     L D +   +GPKG   ++    G  K+TKDG  +   + L  +    G 
Sbjct: 19  ALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMGLHPRIITEGF 78

Query: 96  KLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVM-----LAVDA 150
           +  ++ A    EE          ++R + +E    +++ +   ++   +        VD+
Sbjct: 79  EAAKEKALQFLEEVK--------VSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDS 130

Query: 151 VIAELKKQSKPVTT-PEEIAQVATISANGDKEIGNIISDA------MKKVGRKGVITVKD 203
           ++A +KKQ +P+     EI ++   S      I  ++ D       MKK        V+D
Sbjct: 131 ILA-IKKQDEPIDLFMIEIMEMKHKSETDTSLIRGLVLDHGARHPDMKK-------RVED 182

Query: 204 GKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSIQSIVPALEI 263
              L   + +    ++++  ++  F   S  ++ +   A     E ++  I  +   +  
Sbjct: 183 AYILTCNVSL----EYEKTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKV-C 237

Query: 264 ANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGA 323
            ++ +  +VI  + +D  +L  L     K G  +VA++       ++  ++ + +A GG 
Sbjct: 238 GDSDKGFVVINQKGIDPFSLDALS----KEG--IVALRRA-----KRRNMERLTLACGGV 286

Query: 324 VFGEEGLTLNLEDVQPHDLGKVGEVIVTKDDAMLLKGKGDKAQIEKRIQEIIEQLDVTTS 383
                    + +D+ P  LG  G V                              + T  
Sbjct: 287 ALN------SFDDLSPDCLGHAGLVY-----------------------------EYTLG 311

Query: 384 EYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEGIVL-GGGC 442
           E EK    E+         ++K  G +   + + KD V D L A + A+++G V+ G G 
Sbjct: 312 E-EKFTFIEKCNNPRSVTLLIK--GPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGA 368

Query: 443 ALLRCIPALDSLTPANEDQ-KIGIEIIKRTLKIPAMTIAKNAGVEGSLIVEKIMQSSSE- 500
             +    AL    P+ + + ++G++     L I    +A+N+G +    + KI    SE 
Sbjct: 369 VEVAMAEALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSES 428

Query: 501 ---VGYDAMAGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEVVVTEIPKEEKDPG 557
              VG D   G+ +   E G+ D    V+  LL +    +++ T  ++V EI +     G
Sbjct: 429 GQLVGVDLNTGEPMVAAEVGVWD-NYCVKKQLLHS---CTVIATNILLVDEIMR----AG 480

Query: 558 MGAMGG 563
           M ++ G
Sbjct: 481 MSSLKG 486


>gi|48762932 chaperonin containing TCP1, subunit 8 (theta) [Homo
           sapiens]
          Length = 548

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 105/585 (17%), Positives = 217/585 (37%), Gaps = 90/585 (15%)

Query: 18  LAPHLTRA--YAKDVKFGA-------DARALMLQGVDLLADAVAVTMGPKGRTVIIEQSW 68
           +A H+ +A  +A+ +K GA       +A    +Q    LA       GP G   ++    
Sbjct: 1   MALHVPKAPGFAQMLKEGAKHFSGLEEAVYRNIQACKELAQTTRTAYGPNGMNKMVINHL 60

Query: 69  GSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGF 128
               VT D  T+ + ++++       AK++   ++   +E GDGT    V A ++ +   
Sbjct: 61  EKLFVTNDAATILRELEVQHP----AAKMIVMASHMQEQEVGDGTNFVLVFAGALLELAE 116

Query: 129 EKISKGANPVEIRRGVMLA-------VDAVIAELKKQSKPVTTPEEIAQVATISANGDKE 181
           E +  G +  E+  G  +A       +  ++    K  + +     + + + +S     E
Sbjct: 117 ELLRIGLSVSEVIEGYEIACRKAHEILPNLVCCSAKNLRDIDEVSSLLRTSIMSKQYGNE 176

Query: 182 I--GNIISDAMKKV----GRKGVITVKDGKTLNDEL---EIIEGMKFDRGYISPYFINTS 232
           +    +I+ A   +    G   V  ++  K L   +    ++ GM F +          +
Sbjct: 177 VFLAKLIAQACVSIFPDSGHFNVDNIRVCKILGSGISSSSVLHGMVFKK---------ET 227

Query: 233 KGQKCEFQDAYVLLSEKKISSIQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLK 292
           +G     +DA + +       +        I       L+  AE+         ++N  K
Sbjct: 228 EGDVTSVKDAKIAVYSCPFDGM--------ITETKGTVLIKTAEE---------LMNFSK 270

Query: 293 VGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLTLNLEDVQPHDLGKVGEVIV-- 350
               ++  +     D   N      + TGG V           D+  H   K   ++V  
Sbjct: 271 GEENLMDAQVKAIADTGAN-----VVVTGGKV----------ADMALHYANKYNIMLVRL 315

Query: 351 -TKDDAMLLKGKGDKAQIEKRIQEIIEQLDVTTSEYEKEKLNERLA-----KLSDGVAVL 404
            +K D   L        + +    ++E++    S Y  E  + ++      K    ++ +
Sbjct: 316 NSKWDLRRLCKTVGATALPRLTPPVLEEMGHCDSVYLSEVGDTQVVVFKHEKEDGAISTI 375

Query: 405 KVGGTSDVEVNEKKDRVTDALNATRAAV-EEGIVLGGGCA---LLRCIPALDSLTPANED 460
            + G++D  +++ +  V D +N  +    ++ +V GGG     L + I +     P  E 
Sbjct: 376 VLRGSTDNLMDDIERAVDDGVNTFKVLTRDKRLVPGGGATEIELAKQITSYGETCPGLE- 434

Query: 461 QKIGIEIIKRTLKIPAMTIAKNAGVEGSLIVEKI----MQSSSEVGYD--AMAGDFVNMV 514
            +  I+      +     +A+N+GV+ + ++ K+     + +  VG D  A      +M+
Sbjct: 435 -QYAIKKFAEAFEAIPRALAENSGVKANEVISKLYAVHQEGNKNVGLDIEAEVPAVKDML 493

Query: 515 EKGIIDPTKVVRTALLDAAGVASLLTTAEVVVTEIPKEEKDPGMG 559
           E GI+D       A+  A   A  +   + ++   P     P  G
Sbjct: 494 EAGILDTYLGKYWAIKLATNAAVTVLRVDQIIMAKPAGGPKPPSG 538


>gi|7657253 T-complex protein 1 [Homo sapiens]
          Length = 557

 Score = 37.7 bits (86), Expect = 0.029
 Identities = 25/115 (21%), Positives = 47/115 (40%), Gaps = 4/115 (3%)

Query: 41  LQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQD 100
           L  V  LA  +    GP GR   +    G    T     + ++++L+       A L+++
Sbjct: 37  LAAVQTLASVIRPCYGPHGRQKFLVTMKGETVCTGCATAILRALELEHP----AAWLLRE 92

Query: 101 VANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAEL 155
                 E +GDGT    +L  ++ ++  + +  G    ++R     A   V+A L
Sbjct: 93  AGQTQAENSGDGTAFVVLLTEALLEQAEQLLKAGLPRPQLREAYATATAEVLATL 147


>gi|58331185 chaperonin containing TCP1, subunit 7 isoform b [Homo
           sapiens]
          Length = 339

 Score = 37.4 bits (85), Expect = 0.038
 Identities = 41/173 (23%), Positives = 70/173 (40%), Gaps = 13/173 (7%)

Query: 403 VLKVGGTSDVEVNEKKDRVTDALNATRAAVEEGIVLGGGCA----LLRCIPALDSLTPAN 458
           +L+ G    +E  E+   + DA+   R A++   V+ GG A    L + +       P  
Sbjct: 169 ILRGGAEQFMEETERS--LHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRTIPGK 226

Query: 459 EDQKIGIEIIKRTLKIPAMTIAKNAGVEGSLIVEKI----MQSSSEVGYDAMAGDFVNMV 514
           +   IG     + L+I    +  NAG + + I+ K+     Q  +  G D    D  +  
Sbjct: 227 QQLLIG--AYAKALEIIPRQLCDNAGFDATNILNKLRARHAQGGTWYGVDINNEDIADNF 284

Query: 515 EKGIIDPTKVVRTALLDAAGVASLLTTAEVVVTEIPKEEKDPGMGAMGGMGGG 567
           E  + +P  V   AL  A+  A L+ + +  +   P+   D    A  G G G
Sbjct: 285 EAFVWEPAMVRINALTAASEAACLIVSVDETIKN-PRSTVDAPTAAGRGRGRG 336


>gi|4507363 T-cell acute lymphocytic leukemia 1 [Homo sapiens]
          Length = 331

 Score = 34.7 bits (78), Expect = 0.24
 Identities = 20/52 (38%), Positives = 28/52 (53%)

Query: 519 IDPTKVVRTALLDAAGVASLLTTAEVVVTEIPKEEKDPGMGAMGGMGGGMGG 570
           +   +++R A+     +A LL   E   T+  K  KDP +GA GG GGG GG
Sbjct: 223 LSKNEILRLAMKYINFLAKLLNDQEEEGTQRAKTGKDPVVGAGGGGGGGGGG 274


>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
          Length = 1411

 Score = 34.3 bits (77), Expect = 0.32
 Identities = 34/119 (28%), Positives = 53/119 (44%), Gaps = 11/119 (9%)

Query: 327  EEGLTLNLEDVQPHDLGKVGEVIVTKDDAMLL-------KGKGD--KAQIE--KRIQEII 375
            E+ +T   E+++ H L  + E+   KD   LL       +GK D  KA +E  KR Q+I+
Sbjct: 1137 EKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQIL 1196

Query: 376  EQLDVTTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEE 434
            +       E  K++  E+ AKL   +   +VG     E   K      ALN     V++
Sbjct: 1197 KDQVKKEEEELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKK 1255



 Score = 30.8 bits (68), Expect = 3.5
 Identities = 30/121 (24%), Positives = 54/121 (44%), Gaps = 17/121 (14%)

Query: 359 KGKGDKAQIEKRIQEIIEQLDVTTSE--YEKEKLNERLAKLSDGVAVLKVGGTSDVEVNE 416
           KGK     +EK  +E+  QL V       E+++L + L K  +    LK      +E+N 
Sbjct: 882 KGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLK------LELNS 935

Query: 417 KKDRVTDALNATRAAVEEGIVLGGGCALLRCIPALDSLTPANEDQKIGIEIIKRTLKIPA 476
            ++++  A N  +   +E   L G          ++ L  ++E +K  IE ++  LKI  
Sbjct: 936 MQEQLIQAQNTLKQNEKEEQQLQGN---------INELKQSSEQKKKQIEALQGELKIAV 986

Query: 477 M 477
           +
Sbjct: 987 L 987


>gi|42794779 myosin 18A isoform b [Homo sapiens]
          Length = 2039

 Score = 34.3 bits (77), Expect = 0.32
 Identities = 29/128 (22%), Positives = 63/128 (49%), Gaps = 15/128 (11%)

Query: 310  KNQLKDMAIATGGAVFGEEGLTLNLED--VQPHDLGKVGEVIVTKDDAMLLKGKGDKAQI 367
            KNQL++       AV   + + + +ED  +Q  D+ K    +    +  L + + +K +I
Sbjct: 1689 KNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTAL----EEQLSRLQREKNEI 1744

Query: 368  EKRIQEIIEQLDVTTSEYEK--EKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDAL 425
            + R++E  E ++    +++    + +  LA+++D  A L+       E N++K  + + L
Sbjct: 1745 QNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLE-------EANKEKQELQEKL 1797

Query: 426  NATRAAVE 433
             A ++ VE
Sbjct: 1798 QALQSQVE 1805


>gi|28416946 myosin 18A isoform a [Homo sapiens]
          Length = 2054

 Score = 34.3 bits (77), Expect = 0.32
 Identities = 29/128 (22%), Positives = 63/128 (49%), Gaps = 15/128 (11%)

Query: 310  KNQLKDMAIATGGAVFGEEGLTLNLED--VQPHDLGKVGEVIVTKDDAMLLKGKGDKAQI 367
            KNQL++       AV   + + + +ED  +Q  D+ K    +    +  L + + +K +I
Sbjct: 1689 KNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTAL----EEQLSRLQREKNEI 1744

Query: 368  EKRIQEIIEQLDVTTSEYEK--EKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDAL 425
            + R++E  E ++    +++    + +  LA+++D  A L+       E N++K  + + L
Sbjct: 1745 QNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLE-------EANKEKQELQEKL 1797

Query: 426  NATRAAVE 433
             A ++ VE
Sbjct: 1798 QALQSQVE 1805


>gi|100816407 Bardet-Biedl syndrome 10 [Homo sapiens]
          Length = 723

 Score = 32.7 bits (73), Expect = 0.93
 Identities = 18/75 (24%), Positives = 41/75 (54%), Gaps = 4/75 (5%)

Query: 41  LQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQD 100
           LQ  ++L   V+  +GP+GR V+  +  G   ++++G  + +++ L+       A+++ D
Sbjct: 15  LQVAEVLEAIVSCCVGPEGRQVLCTKPTGEVLLSRNGGRLLEALHLEHPI----ARMIVD 70

Query: 101 VANNTNEEAGDGTTT 115
             ++  ++ GDG  T
Sbjct: 71  CVSSHLKKTGDGAKT 85


>gi|83716024 kinesin family member 21B [Homo sapiens]
          Length = 1624

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 29/115 (25%), Positives = 52/115 (45%), Gaps = 18/115 (15%)

Query: 286 LVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLTLNLEDVQPHDLGKV 345
           +V+N+ K   Q+ A++A    +  + Q++ M    G  V GE+G                
Sbjct: 374 VVVNQDKTSQQISALRA----EIARLQMELMEYKAGKRVIGEDGAE-------------- 415

Query: 346 GEVIVTKDDAMLLKGKGDKAQIEKRIQEIIEQLDVTTSEYEKEKLNERLAKLSDG 400
           G   + +++AML K  G      K +QE I+ ++   ++   ++ N  LAK  DG
Sbjct: 416 GYSDLFRENAMLQKENGALRLRVKAMQEAIDAINNRVTQLMSQEANLLLAKAGDG 470


>gi|4885409 high density lipoprotein binding protein [Homo sapiens]
          Length = 1268

 Score = 31.6 bits (70), Expect = 2.1
 Identities = 34/103 (33%), Positives = 48/103 (46%), Gaps = 6/103 (5%)

Query: 351 TKDDAMLLKGKGDKAQI-EKRIQEIIEQLDV-TTSEYEKEKLNERLAKLSDGVAVLKVGG 408
           T+ D + LKG  D  +  +KRIQEIIE L+   T E    +   R      G  + ++  
Sbjct: 842 TQSDKVTLKGAKDCVEAAKKRIQEIIEDLEAQVTLECAIPQKFHRSVMGPKGSRIQQI-- 899

Query: 409 TSDVEVNEK-KDRVTDALNATRAAVEE-GIVLGGGCALLRCIP 449
           T D  V  K  DR  +A+++T   V+E G   G G     C P
Sbjct: 900 TRDFSVQIKFPDREENAVHSTEPVVQENGDEAGEGREAKDCDP 942


>gi|42716280 high density lipoprotein binding protein [Homo sapiens]
          Length = 1268

 Score = 31.6 bits (70), Expect = 2.1
 Identities = 34/103 (33%), Positives = 48/103 (46%), Gaps = 6/103 (5%)

Query: 351 TKDDAMLLKGKGDKAQI-EKRIQEIIEQLDV-TTSEYEKEKLNERLAKLSDGVAVLKVGG 408
           T+ D + LKG  D  +  +KRIQEIIE L+   T E    +   R      G  + ++  
Sbjct: 842 TQSDKVTLKGAKDCVEAAKKRIQEIIEDLEAQVTLECAIPQKFHRSVMGPKGSRIQQI-- 899

Query: 409 TSDVEVNEK-KDRVTDALNATRAAVEE-GIVLGGGCALLRCIP 449
           T D  V  K  DR  +A+++T   V+E G   G G     C P
Sbjct: 900 TRDFSVQIKFPDREENAVHSTEPVVQENGDEAGEGREAKDCDP 942


>gi|156151379 suppressor of IKK epsilon isoform 1 [Homo sapiens]
          Length = 211

 Score = 30.8 bits (68), Expect = 3.5
 Identities = 18/87 (20%), Positives = 45/87 (51%), Gaps = 1/87 (1%)

Query: 348 VIVTKDDAMLLKGKGDKAQIEKRIQEIIEQLDVTTSEYEKEKLNERLAKLS-DGVAVLKV 406
           +++++++  +   + +  ++   ++E  + L++  S+Y K+ L   +AK + D   VLK 
Sbjct: 75  ILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDAEPVLKA 134

Query: 407 GGTSDVEVNEKKDRVTDALNATRAAVE 433
             +   E+  + DR+ +     R AV+
Sbjct: 135 HQSHSAEIESQIDRICEMGEVMRKAVQ 161


>gi|156151377 suppressor of IKK epsilon isoform 2 [Homo sapiens]
          Length = 207

 Score = 30.8 bits (68), Expect = 3.5
 Identities = 18/87 (20%), Positives = 45/87 (51%), Gaps = 1/87 (1%)

Query: 348 VIVTKDDAMLLKGKGDKAQIEKRIQEIIEQLDVTTSEYEKEKLNERLAKLS-DGVAVLKV 406
           +++++++  +   + +  ++   ++E  + L++  S+Y K+ L   +AK + D   VLK 
Sbjct: 71  ILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDAEPVLKA 130

Query: 407 GGTSDVEVNEKKDRVTDALNATRAAVE 433
             +   E+  + DR+ +     R AV+
Sbjct: 131 HQSHSAEIESQIDRICEMGEVMRKAVQ 157


>gi|33188443 microfilament and actin filament cross-linker protein
            isoform b [Homo sapiens]
          Length = 5938

 Score = 30.0 bits (66), Expect = 6.0
 Identities = 35/134 (26%), Positives = 61/134 (45%), Gaps = 26/134 (19%)

Query: 308  NRKNQLKDMAIATGGAVFGEEGLTLNLEDVQPHDLGKVGEVIVTKD----DAMLLKGKGD 363
            +R+++LKD         +  E L   +ED +     K+ E+ VT D    ++ LL+ K  
Sbjct: 3333 DRQSRLKDCMQKAQKYQWHVEDLVPWIEDCK----AKMSELRVTLDPVQLESSLLRSKAM 3388

Query: 364  KAQIEKR--IQEIIEQL-DVTTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDR 420
              ++EKR  + EI+    D+  +  E ++         DG+   K G      +N+  D 
Sbjct: 3389 LNEVEKRRSLLEILNSAADILINSSEADE---------DGIRDEKAG------INQNMDA 3433

Query: 421  VTDALNATRAAVEE 434
            VT+ L A   ++EE
Sbjct: 3434 VTEELQAKTGSLEE 3447


>gi|33188445 microfilament and actin filament cross-linker protein
            isoform a [Homo sapiens]
          Length = 5430

 Score = 30.0 bits (66), Expect = 6.0
 Identities = 35/134 (26%), Positives = 61/134 (45%), Gaps = 26/134 (19%)

Query: 308  NRKNQLKDMAIATGGAVFGEEGLTLNLEDVQPHDLGKVGEVIVTKD----DAMLLKGKGD 363
            +R+++LKD         +  E L   +ED +     K+ E+ VT D    ++ LL+ K  
Sbjct: 2831 DRQSRLKDCMQKAQKYQWHVEDLVPWIEDCK----AKMSELRVTLDPVQLESSLLRSKAM 2886

Query: 364  KAQIEKR--IQEIIEQL-DVTTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDR 420
              ++EKR  + EI+    D+  +  E ++         DG+   K G      +N+  D 
Sbjct: 2887 LNEVEKRRSLLEILNSAADILINSSEADE---------DGIRDEKAG------INQNMDA 2931

Query: 421  VTDALNATRAAVEE 434
            VT+ L A   ++EE
Sbjct: 2932 VTEELQAKTGSLEE 2945


>gi|6912482 leucine zipper-EF-hand containing transmembrane protein
           1 [Homo sapiens]
          Length = 739

 Score = 29.6 bits (65), Expect = 7.8
 Identities = 23/72 (31%), Positives = 42/72 (58%), Gaps = 4/72 (5%)

Query: 327 EEGLTLNLEDVQPH--DLGKVG-EVIVTKDDAMLLKGKGDKAQIEKRIQEIIEQLDVTTS 383
           +E L L  EDVQ +  DL ++  E+  T ++  + + K  K ++ KR+Q++I Q+D   S
Sbjct: 566 KEELELLKEDVQDYSEDLQEIKKELSKTGEEKYVEESKASK-RLTKRVQQMIGQIDGLIS 624

Query: 384 EYEKEKLNERLA 395
           + E ++   +LA
Sbjct: 625 QLEMDQQAGKLA 636


>gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor
           [Homo sapiens]
          Length = 1336

 Score = 29.6 bits (65), Expect = 7.8
 Identities = 12/21 (57%), Positives = 14/21 (66%)

Query: 550 PKEEKDPGMGAMGGMGGGMGG 570
           P  E+ PG G  GG GGG+GG
Sbjct: 27  PFPEEAPGPGGAGGPGGGLGG 47


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.133    0.360 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,893,635
Number of Sequences: 37866
Number of extensions: 781883
Number of successful extensions: 2980
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 27
Number of HSP's that attempted gapping in prelim test: 2922
Number of HSP's gapped (non-prelim): 77
length of query: 573
length of database: 18,247,518
effective HSP length: 108
effective length of query: 465
effective length of database: 14,157,990
effective search space: 6583465350
effective search space used: 6583465350
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.