Guide to the Human Genome
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Search of human proteins with 41349486

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|41349486 proline-rich protein BstNI subfamily 1 isoform 3
preproprotein [Homo sapiens]
         (178 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|41349486 proline-rich protein BstNI subfamily 1 isoform 3 pre...   390   e-109
gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2 pre...   379   e-105
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...   307   4e-84
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]    298   1e-81
gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho...   276   9e-75
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H...   242   1e-64
gi|154800441 proline-rich protein HaeIII subfamily 1 [Homo sapiens]   163   8e-41
gi|158966674 proline-rich protein HaeIII subfamily 2 [Homo sapiens]   160   4e-40
gi|4826944 proline-rich protein HaeIII subfamily 2 [Homo sapiens]     160   4e-40
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...    97   7e-21
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    92   2e-19
gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]               92   2e-19
gi|7706501 WW domain binding protein 11 [Homo sapiens]                 86   2e-17
gi|19924099 synapsin I isoform Ia [Homo sapiens]                       83   1e-16
gi|19924097 synapsin I isoform Ib [Homo sapiens]                       83   1e-16
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap...    80   7e-16
gi|57165375 glutamate receptor, ionotropic, N-methyl D-aspartate...    80   7e-16
gi|57165373 glutamate receptor, ionotropic, N-methyl D-aspartate...    80   7e-16
gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]             80   9e-16
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]                80   1e-15
gi|48762934 alpha 2 type I collagen [Homo sapiens]                     79   2e-15
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]       79   2e-15
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]                     79   3e-15
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]                     79   3e-15
gi|160707881 formin 2 [Homo sapiens]                                   78   3e-15
gi|163965366 nascent polypeptide-associated complex alpha subuni...    78   3e-15
gi|11386183 WAS protein family, member 2 [Homo sapiens]                78   5e-15
gi|119829187 alpha 1 type XVII collagen [Homo sapiens]                 78   5e-15
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]          77   6e-15
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      76   1e-14

>gi|41349486 proline-rich protein BstNI subfamily 1 isoform 3
           preproprotein [Homo sapiens]
          Length = 178

 Score =  390 bits (1003), Expect = e-109
 Identities = 178/178 (100%), Positives = 178/178 (100%)

Query: 1   MLLILLSVALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGP 60
           MLLILLSVALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGP
Sbjct: 1   MLLILLSVALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGP 60

Query: 61  PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQS 120
           PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQS
Sbjct: 61  PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQS 120

Query: 121 ARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ 178
           ARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ
Sbjct: 121 ARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ 178


>gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2
           preproprotein [Homo sapiens]
          Length = 198

 Score =  379 bits (972), Expect = e-105
 Identities = 178/198 (89%), Positives = 178/198 (89%), Gaps = 20/198 (10%)

Query: 1   MLLILLSVALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGP 60
           MLLILLSVALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGP
Sbjct: 1   MLLILLSVALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGP 60

Query: 61  PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQG---------------- 104
           PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQG                
Sbjct: 61  PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGKPQGPPPQGGNKPQG 120

Query: 105 ----GKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQ 160
               GKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQ
Sbjct: 121 PPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQ 180

Query: 161 PQGPPRPPQGGRPSRPPQ 178
           PQGPPRPPQGGRPSRPPQ
Sbjct: 181 PQGPPRPPQGGRPSRPPQ 198


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score =  307 bits (786), Expect = 4e-84
 Identities = 141/185 (76%), Positives = 144/185 (77%), Gaps = 31/185 (16%)

Query: 25  QEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG 84
           +  SP    G PQGP PQGGN+PQGPPPPPGKPQGPPPQGG KPQGPPPPGKPQGPPPQG
Sbjct: 147 KSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQG 206

Query: 85  DKSRSPRSPPGKPQGPPPQGG-------------------------------KPQGPPAQ 113
           DKSRS +SPPGKPQGPPPQGG                               KPQGPPAQ
Sbjct: 207 DKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQ 266

Query: 114 GGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRP 173
           GGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRP
Sbjct: 267 GGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRP 326

Query: 174 SRPPQ 178
           SRPPQ
Sbjct: 327 SRPPQ 331



 Score =  303 bits (777), Expect = 4e-83
 Identities = 152/207 (73%), Positives = 156/207 (75%), Gaps = 34/207 (16%)

Query: 1   MLLILLSVALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGP 60
           MLLILLSVALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGP
Sbjct: 1   MLLILLSVALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGP 60

Query: 61  PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQG-----------GKPQG 109
           PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQG           GKPQG
Sbjct: 61  PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 120

Query: 110 PPAQGGS-------------------KSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNP 150
           PP QGG+                   KS+S RSPPGKPQGPP Q GN PQGPPPP  G P
Sbjct: 121 PPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPP-GKP 179

Query: 151 QQPQAPPAGQPQGPPRPPQGGRPSRPP 177
           Q P      +PQGPP P   G+P  PP
Sbjct: 180 QGPPPQGGKKPQGPPPP---GKPQGPP 203


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score =  298 bits (764), Expect = 1e-81
 Identities = 138/177 (77%), Positives = 140/177 (79%), Gaps = 32/177 (18%)

Query: 34  GNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG-DKSRSPRS 92
           G PQGP PQGGN+PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG  KSRS RS
Sbjct: 240 GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRS 299

Query: 93  PPGKPQGPPPQGG-------------------------------KPQGPPAQGGSKSQSA 121
           PPGKPQGPPPQGG                               KPQGPP QGGSKS+SA
Sbjct: 300 PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSA 359

Query: 122 RSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ 178
           RSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ
Sbjct: 360 RSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ 416



 Score =  286 bits (731), Expect = 8e-78
 Identities = 148/229 (64%), Positives = 153/229 (66%), Gaps = 56/229 (24%)

Query: 1   MLLILLSVALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQ-- 58
           MLLILLSVALLALSSAQNLNEDVSQEESPSLIAGNPQG  PQGGNKPQGPP PPGKPQ  
Sbjct: 1   MLLILLSVALLALSSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGP 60

Query: 59  -------------------GPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQG 99
                              GPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQG
Sbjct: 61  PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQG 120

Query: 100 PPPQG-------------------------------GKPQGPPAQGGSKSQSARSPPGKP 128
           PPPQG                               GKPQGPP QG +KS+S+RSPPGKP
Sbjct: 121 PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKP 180

Query: 129 QGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 177
           QGPP Q GN PQGPPPP  G PQ P      +PQGPP P   G+P  PP
Sbjct: 181 QGPPPQGGNQPQGPPPPP-GKPQGPPPQGGNKPQGPPPP---GKPQGPP 225



 Score =  243 bits (619), Expect = 8e-65
 Identities = 124/191 (64%), Positives = 128/191 (67%), Gaps = 42/191 (21%)

Query: 25  QEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG 84
           +  SP    G PQGP PQGGN+PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG
Sbjct: 107 KSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG 166

Query: 85  D-KSRSPRSPPGKPQGPPPQG-------------------------------GKPQGPPA 112
           D KSRS RSPPGKPQGPPPQG                               GKPQGPP 
Sbjct: 167 DNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP 226

Query: 113 QGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAG---GNPQQ----PQA-PPAGQPQGP 164
           QG +KSQSARSPPGKPQGPP Q GN PQGPPPP G   G P Q    PQ  PP G+PQGP
Sbjct: 227 QGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP 286

Query: 165 PRPPQGGRPSR 175
             PPQGG  SR
Sbjct: 287 --PPQGGSKSR 295


>gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo
           sapiens]
          Length = 247

 Score =  276 bits (705), Expect = 9e-75
 Identities = 143/241 (59%), Positives = 158/241 (65%), Gaps = 63/241 (26%)

Query: 1   MLLILLSVALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGP 60
           MLLILLSVALLALSSA++ +EDVSQEES  LI+G P+G  PQGGN+PQ PPPPPGKPQGP
Sbjct: 1   MLLILLSVALLALSSAESSSEDVSQEESLFLISGKPEGRRPQGGNQPQRPPPPPGKPQGP 60

Query: 61  PPQGGNKPQGPPPP-------------------------------------------GKP 77
           PPQGGN+ QGPPPP                                           GKP
Sbjct: 61  PPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPPHPGKPERPPPQGGNQSQGTPPPPGKP 120

Query: 78  QGPPPQG-DKSRSPRSPPGKPQGPPPQGG-----------KPQGPPAQGGSKSQSARSPP 125
           + PPPQG ++S  P  PPGKP+ PPPQGG           KP+GPP Q G+KS+SARSPP
Sbjct: 121 ERPPPQGGNQSHRPPPPPGKPERPPPQGGNQSQGPPPHPGKPEGPPPQEGNKSRSARSPP 180

Query: 126 GKPQGPPQQEGNNPQGP--------PPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 177
           GKPQGPPQQEGN PQGP        PPPAGGNPQQPQAPPAG+PQGPP PPQGGRP RP 
Sbjct: 181 GKPQGPPQQEGNKPQGPPPPGKPQGPPPAGGNPQQPQAPPAGKPQGPPPPPQGGRPPRPA 240

Query: 178 Q 178
           Q
Sbjct: 241 Q 241



 Score =  145 bits (365), Expect = 2e-35
 Identities = 79/155 (50%), Positives = 87/155 (56%), Gaps = 47/155 (30%)

Query: 34  GNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPP-PGKPQGPPPQ-GDKSRSPR 91
           G P+ P PQGGN+   PPPPPGKP+ PPPQGGN+ QGPPP PGKP+GPPPQ G+KSRS R
Sbjct: 118 GKPERPPPQGGNQSHRPPPPPGKPERPPPQGGNQSQGPPPHPGKPEGPPPQEGNKSRSAR 177

Query: 92  SPPGKP--------------------QGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGP 131
           SPPGKP                    QGPPP GG PQ P A           P GKPQGP
Sbjct: 178 SPPGKPQGPPQQEGNKPQGPPPPGKPQGPPPAGGNPQQPQA----------PPAGKPQGP 227

Query: 132 PQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPR 166
                     PPPP GG P +P      Q Q PP+
Sbjct: 228 ----------PPPPQGGRPPRP-----AQGQQPPQ 247


>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
           sapiens]
          Length = 309

 Score =  242 bits (617), Expect = 1e-64
 Identities = 123/199 (61%), Positives = 142/199 (71%), Gaps = 24/199 (12%)

Query: 1   MLLILLSVALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGP 60
           MLLILLSVALLALSSAQ+LNEDVSQEESPS+I+G P+G  PQGGN+PQ  PPPPGKP+G 
Sbjct: 1   MLLILLSVALLALSSAQSLNEDVSQEESPSVISGKPEGRRPQGGNQPQRTPPPPGKPEGR 60

Query: 61  PPQGGNKPQGPPP-PGKPQGPPPQ-GDKSRSPRSPPGKPQGPPPQG-----------GKP 107
           PPQGGN+ QGPPP PGKP+GPPPQ G++S+ P   PGKP+G PPQG           GKP
Sbjct: 61  PPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKP 120

Query: 108 QGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGP---------PPPAGGNPQQPQAPPA 158
           +GPP QGG++SQ     PGKP+GPP Q GN  QGP         PPP GGN  Q   P  
Sbjct: 121 EGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHP 180

Query: 159 GQPQGPPRPPQGGRPSRPP 177
           G+P+GP  PPQGG  S+ P
Sbjct: 181 GKPEGP--PPQGGNQSQGP 197



 Score =  238 bits (608), Expect = 2e-63
 Identities = 111/176 (63%), Positives = 126/176 (71%), Gaps = 21/176 (11%)

Query: 24  SQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPP-PGKPQGPPP 82
           +Q + P    G P+GP PQGGN+ QGPPP PGKP+GPPPQGGN+ QGPPP PGKP+GPPP
Sbjct: 129 NQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPP 188

Query: 83  Q-GDKSRSPRSPPGKPQGPPPQG-----------GKPQGPPAQGGSKSQSARSPPGKPQG 130
           Q G++S+ P   PGKP+GPPPQG           GKP+GPP+QGG+K Q     PGKPQG
Sbjct: 189 QGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQG 248

Query: 131 PPQQEGNNPQGPPPPA--------GGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ 178
           PP QEGN PQ PPPP         GGNPQQP  PPAG+PQGPP PPQGGRP RPPQ
Sbjct: 249 PPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHRPPQ 304



 Score =  158 bits (399), Expect = 3e-39
 Identities = 80/140 (57%), Positives = 89/140 (63%), Gaps = 26/140 (18%)

Query: 24  SQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPP-PGKPQGPPP 82
           +Q + P    G P+GP PQGGN+ QGPPP PGKP+GPP QGGNKPQGPPP PGKPQGPPP
Sbjct: 192 NQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPP 251

Query: 83  Q-GDKSRSPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQG 141
           Q G+K + P  PPG+PQGPPP GG PQ P             P GKPQGP          
Sbjct: 252 QEGNKPQRP-PPPGRPQGPPPPGGNPQQP----------LPPPAGKPQGP---------- 290

Query: 142 PPPPAGGNPQQPQAPPAGQP 161
           PPPP GG P +   PP GQP
Sbjct: 291 PPPPQGGRPHR---PPQGQP 307



 Score = 47.4 bits (111), Expect = 7e-06
 Identities = 26/52 (50%), Positives = 27/52 (51%), Gaps = 19/52 (36%)

Query: 34  GNPQGPSPQGGN----------KPQGPPPPP--GKPQGPPPQGGNKPQGPPP 73
           G PQGP P GGN          KPQGPPPPP  G+P  P       PQG PP
Sbjct: 264 GRPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHRP-------PQGQPP 308


>gi|154800441 proline-rich protein HaeIII subfamily 1 [Homo sapiens]
          Length = 166

 Score =  163 bits (412), Expect = 8e-41
 Identities = 102/198 (51%), Positives = 112/198 (56%), Gaps = 57/198 (28%)

Query: 1   MLLILLSVALLALSSAQNLNEDVSQEESPSLIA--------------GNPQG-----PSP 41
           MLLILLSVALLA SSAQ+LNEDVSQE+ P +I+              G P G     PS 
Sbjct: 1   MLLILLSVALLAFSSAQDLNEDVSQEDVPLVISDGGDSEQFLDEERQGPPLGGQQSQPSA 60

Query: 42  QGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPP-GKPQGPPPQGDKSRSPRSPPGKPQGP 100
             GN+  GP       QGPP QGG + QGPPPP GKPQGPP QG               P
Sbjct: 61  GDGNQDDGPQ------QGPPQQGGQQQQGPPPPQGKPQGPPQQGGH-------------P 101

Query: 101 PPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQ 160
           PP  G+PQGPP QGG      R P G+PQGPPQQ G + QGPPPP           P G+
Sbjct: 102 PPPQGRPQGPPQQGG----HPRPPRGRPQGPPQQ-GGHQQGPPPP-----------PPGK 145

Query: 161 PQGPPRPPQGGRPSRPPQ 178
           PQGP  PPQGGRP  PPQ
Sbjct: 146 PQGP--PPQGGRPQGPPQ 161


>gi|158966674 proline-rich protein HaeIII subfamily 2 [Homo sapiens]
          Length = 166

 Score =  160 bits (406), Expect = 4e-40
 Identities = 101/198 (51%), Positives = 112/198 (56%), Gaps = 57/198 (28%)

Query: 1   MLLILLSVALLALSSAQNLNEDVSQEESPSLIA--------------GNPQG-----PSP 41
           MLLILLSVALLA SSAQ+L+EDVSQE+ P +I+              G P G     PS 
Sbjct: 1   MLLILLSVALLAFSSAQDLDEDVSQEDVPLVISDGGDSEQFIDEERQGPPLGGQQSQPSA 60

Query: 42  QGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPP-GKPQGPPPQGDKSRSPRSPPGKPQGP 100
             GN+  GP       QGPP QGG + QGPPPP GKPQGPP QG               P
Sbjct: 61  GDGNQNDGPQ------QGPPQQGGQQQQGPPPPQGKPQGPPQQGGH-------------P 101

Query: 101 PPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQ 160
           PP  G+PQGPP QGG      R P G+PQGPPQQ G + QGPPPP           P G+
Sbjct: 102 PPPQGRPQGPPQQGG----HPRPPRGRPQGPPQQ-GGHQQGPPPP-----------PPGK 145

Query: 161 PQGPPRPPQGGRPSRPPQ 178
           PQGP  PPQGGRP  PPQ
Sbjct: 146 PQGP--PPQGGRPQGPPQ 161


>gi|4826944 proline-rich protein HaeIII subfamily 2 [Homo sapiens]
          Length = 166

 Score =  160 bits (406), Expect = 4e-40
 Identities = 101/198 (51%), Positives = 112/198 (56%), Gaps = 57/198 (28%)

Query: 1   MLLILLSVALLALSSAQNLNEDVSQEESPSLIA--------------GNPQG-----PSP 41
           MLLILLSVALLA SSAQ+L+EDVSQE+ P +I+              G P G     PS 
Sbjct: 1   MLLILLSVALLAFSSAQDLDEDVSQEDVPLVISDGGDSEQFIDEERQGPPLGGQQSQPSA 60

Query: 42  QGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPP-GKPQGPPPQGDKSRSPRSPPGKPQGP 100
             GN+  GP       QGPP QGG + QGPPPP GKPQGPP QG               P
Sbjct: 61  GDGNQNDGPQ------QGPPQQGGQQQQGPPPPQGKPQGPPQQGGH-------------P 101

Query: 101 PPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQ 160
           PP  G+PQGPP QGG      R P G+PQGPPQQ G + QGPPPP           P G+
Sbjct: 102 PPPQGRPQGPPQQGG----HPRPPRGRPQGPPQQ-GGHQQGPPPP-----------PPGK 145

Query: 161 PQGPPRPPQGGRPSRPPQ 178
           PQGP  PPQGGRP  PPQ
Sbjct: 146 PQGP--PPQGGRPQGPPQ 161


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
           subunit [Homo sapiens]
          Length = 551

 Score = 97.1 bits (240), Expect = 7e-21
 Identities = 63/165 (38%), Positives = 69/165 (41%), Gaps = 34/165 (20%)

Query: 29  PSLIAGNPQGPSPQGGNKPQGPPPP-------PGKPQGPPPQGGNKPQGPPPPGKPQGPP 81
           P  + G  + P P G   P GPPPP       P  P GPP   G  P GPPPPG+   PP
Sbjct: 208 PGAVPGGDRFPGPAG---PGGPPPPFPAGQTPPRPPLGPPGPPG--PPGPPPPGQVLPPP 262

Query: 82  PQGDKSRSPRSPP-----GKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEG 136
             G  +R  R PP     G+P G PP G  P GPP            PP    GPP    
Sbjct: 263 LAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPP------------PPVPGYGPPPGPP 310

Query: 137 NNPQGPPPPAGGNPQQPQAP-----PAGQPQGPPRPPQGGRPSRP 176
              QGPPPP G  P +P  P         P   P PP G  P  P
Sbjct: 311 PPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAP 355



 Score = 77.8 bits (190), Expect = 5e-15
 Identities = 62/175 (35%), Positives = 64/175 (36%), Gaps = 42/175 (24%)

Query: 34  GNPQGPSPQGGNKPQ---GPPPPPGKPQGPPPQG-------------------------- 64
           G P  P P G   P+   GPP PPG P GPPP G                          
Sbjct: 224 GGPPPPFPAGQTPPRPPLGPPGPPGPP-GPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQ 282

Query: 65  --GNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGK-PQGPPAQGGSKSQSA 121
             G  P GP PPG P   P  G     P  PP   QGPPP  G  P  PP   G     A
Sbjct: 283 PFGQPPLGPLPPGPPPPVPGYG----PPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLA 338

Query: 122 RSP--PGKPQG--PPQQEGNNPQGPPPPAGGNP-QQPQAPPAGQPQGPPRPPQGG 171
             P  PG P G  PP    N    PPP   G P    + PP   P G P P   G
Sbjct: 339 PPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRG 393



 Score = 60.8 bits (146), Expect = 6e-10
 Identities = 44/115 (38%), Positives = 52/115 (45%), Gaps = 14/115 (12%)

Query: 72  PPPGKPQGPPPQGDKSRS--PRSPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQ 129
           PP G  +   PQG + R   P + PG  + P P G  P GPP    +  Q+   PP  P 
Sbjct: 188 PPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAG--PGGPPPPFPA-GQTPPRPPLGPP 244

Query: 130 GPPQQEGNNPQGP--PPPAGGNPQQPQAPP-----AGQPQGPPRPPQGGRPSRPP 177
           GPP   G  P G   PPP  G P +   PP      GQP G  +PP G  P  PP
Sbjct: 245 GPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFG--QPPLGPLPPGPP 297



 Score = 57.0 bits (136), Expect = 8e-09
 Identities = 42/114 (36%), Positives = 44/114 (38%), Gaps = 23/114 (20%)

Query: 34  GNPQGPSPQGGNKPQGPPPPPGK--PQGPPPQGGNKPQGPPP--PGKPQGPPPQGDKSRS 89
           G P GP P      QGPPPPPG   P+ P P G      PPP  PG P G PP       
Sbjct: 304 GPPPGPPPP----QQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPP------ 353

Query: 90  PRSPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPP 143
             +P   P   PP       P   G   S S   PP  P G P        GPP
Sbjct: 354 --APHVNPAFFPP-------PTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPP 398



 Score = 45.1 bits (105), Expect = 3e-05
 Identities = 32/98 (32%), Positives = 41/98 (41%), Gaps = 8/98 (8%)

Query: 83  QGDKSRSPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGP 142
           Q  K+       G+ +  PP G      P  G  + +   + PG  + P       P GP
Sbjct: 170 QSRKTTQSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPA---GPGGP 226

Query: 143 PPP--AGGNPQQPQ-APPAGQPQGPPRPPQGGRPSRPP 177
           PPP  AG  P +P   PP   P GPP PP  G+   PP
Sbjct: 227 PPPFPAGQTPPRPPLGPPG--PPGPPGPPPPGQVLPPP 262


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 92.0 bits (227), Expect = 2e-19
 Identities = 64/152 (42%), Positives = 70/152 (46%), Gaps = 26/152 (17%)

Query: 36  PQGPSP-QGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPP 94
           P GP P Q G KP  PPPPP + Q  PP     PQ PPP   P  P PQ  + + P  PP
Sbjct: 46  PMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPP--PHPQPHQQQQPPPPP 103

Query: 95  ---GKP---QGPPPQGGKPQGPPAQGGSKSQSARSPPGKP--QGPPQQEGNNPQGPPPPA 146
               KP   QGP P  G    PPA       S+ +PP  P   G P   G  P   PPPA
Sbjct: 104 QDSSKPVVAQGPGPAPGVGSAPPA-------SSSAPPATPPTSGAPPGSGPGPTPTPPPA 156

Query: 147 GGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ 178
                   APP G P  PP PP  G P+ PPQ
Sbjct: 157 -----VTSAPP-GAP--PPTPPSSGVPTTPPQ 180



 Score = 79.0 bits (193), Expect = 2e-15
 Identities = 63/189 (33%), Positives = 75/189 (39%), Gaps = 33/189 (17%)

Query: 17  QNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPP-----PGKPQGP---------PP 62
           Q   +   Q+  P     +   P PQ   + Q PPPP     P   QGP         PP
Sbjct: 67  QQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPP 126

Query: 63  QGGNKPQGPP-----PPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGKPQGPPAQGGSK 117
              + P   P     PPG   GP P    + +  +PPG P   PP  G P  PP  GG  
Sbjct: 127 ASSSAPPATPPTSGAPPGSGPGPTPTPPPAVT-SAPPGAPPPTPPSSGVPTTPPQAGGPP 185

Query: 118 SQSARSP---PGKPQGP---PQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPR---PP 168
              A  P   PG  QGP     + G  P GP P  GG P    + P G P+ P R    P
Sbjct: 186 PPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKP--GGGP--GLSTPGGHPKPPHRGGGEP 241

Query: 169 QGGRPSRPP 177
           +GGR   PP
Sbjct: 242 RGGRQHHPP 250



 Score = 68.6 bits (166), Expect = 3e-12
 Identities = 54/141 (38%), Positives = 62/141 (43%), Gaps = 23/141 (16%)

Query: 33  AGNPQGPSPQGGNKPQGPPP----PPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSR 88
           +G P G  P  G  P  PP     PPG P   PP  G  P  PP  G P  PP     + 
Sbjct: 139 SGAPPGSGP--GPTPTPPPAVTSAPPGAPPPTPPSSG-VPTTPPQAGGPPPPP-----AA 190

Query: 89  SPRSPPGKPQGP---PPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQG---P 142
            P   PG  QGP    P+GGK  G P  GG    S  +P G P+ PP + G  P+G    
Sbjct: 191 VPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLS--TPGGHPK-PPHRGGGEPRGGRQH 247

Query: 143 PPPAGGNPQQPQAPPAGQPQG 163
            PP   + Q  Q PP G P G
Sbjct: 248 HPPY--HQQHHQGPPPGGPGG 266



 Score = 52.0 bits (123), Expect = 3e-07
 Identities = 38/115 (33%), Positives = 50/115 (43%), Gaps = 15/115 (13%)

Query: 33  AGNPQGPSPQGGNKPQG---PPPPPGKPQGPPP---QGGNKPQGPPPPGKPQGPPPQGDK 86
           +G P  P   GG  P     P P PG  QGP P   +GG  P GP P G P    P G  
Sbjct: 172 SGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHP 231

Query: 87  SRSPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQG 141
                 PP +  G  P+GG+   PP     +      PPG P G  +++ ++ +G
Sbjct: 232 K-----PPHR-GGGEPRGGRQHHPPYH---QQHHQGPPPGGPGGRSEEKISDSEG 277



 Score = 50.8 bits (120), Expect = 6e-07
 Identities = 31/75 (41%), Positives = 33/75 (44%), Gaps = 5/75 (6%)

Query: 98  QGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPP 157
           + PPP  G  Q     G    QS   PP  P  P QQ+   P   PPP    P QP  PP
Sbjct: 32  RSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQP--PP 89

Query: 158 AGQP---QGPPRPPQ 169
             QP   Q PP PPQ
Sbjct: 90  HPQPHQQQQPPPPPQ 104


>gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]
          Length = 1336

 Score = 92.0 bits (227), Expect = 2e-19
 Identities = 62/142 (43%), Positives = 68/142 (47%), Gaps = 10/142 (7%)

Query: 39  PSPQGGNKPQGPPPPPGKPQGPP-PQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKP 97
           P PQG  +P GP    G PQGPP  QGG  PQG   P  PQGPP    + +    P G  
Sbjct: 620 PGPQGQFRPPGPQGQMG-PQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQ 678

Query: 98  QGPPPQGG-KPQGPPAQGGSKSQSARSPPGKPQGPPQQEGN-NPQGPPPPAGGNPQQPQA 155
           + P P G   PQGPP   GS           PQGPP  +G+  PQGPP P G     PQ 
Sbjct: 679 RHPGPHGPLGPQGPPGPQGSSGPQGHM---GPQGPPGPQGHIGPQGPPGPQG--HLGPQG 733

Query: 156 PPAGQ-PQGPPRPPQGGRPSRP 176
           PP  Q  QGPP P     P  P
Sbjct: 734 PPGTQGMQGPPGPRGMQGPPHP 755



 Score = 87.4 bits (215), Expect = 6e-18
 Identities = 81/210 (38%), Positives = 91/210 (43%), Gaps = 71/210 (33%)

Query: 36  PQG----PSPQGGNKPQGPPPPPGK--------PQGPP-PQGGNKPQGPPPPG---KPQG 79
           PQG    P P G   PQGPP P G         PQGPP PQG   PQGPP P     PQG
Sbjct: 674 PQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQG 733

Query: 80  PP-------PQGDKS-RSPRSPPGKPQGPPPQGGKPQGPPAQG---GSKSQSARSPPG-- 126
           PP       P G +  + P  P G   GP  QG   QGP +QG   G   +  + PPG  
Sbjct: 734 PPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQG--IQGPVSQGPLMGLNPRGMQGPPGPR 791

Query: 127 -----KPQG-----PPQQE----------GNNPQ---GP--------PPPAG---GNPQQ 152
                 PQG     PPQ+           G+ PQ   GP        PPP G   G PQ+
Sbjct: 792 ENQGPAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQE 851

Query: 153 PQAPPAGQ-PQGPPR-----PPQGGRPSRP 176
            + PP  Q  QGPP+     PPQGG    P
Sbjct: 852 LRGPPGSQSQQGPPQGSLGPPPQGGMQGPP 881



 Score = 85.5 bits (210), Expect = 2e-17
 Identities = 75/194 (38%), Positives = 81/194 (41%), Gaps = 58/194 (29%)

Query: 36  PQG----PSPQGGNKPQGPP-----------PPPGKPQGPP-----------PQGGNKPQ 69
           PQG    P PQG   PQGPP             P  PQGPP           PQG  +  
Sbjct: 622 PQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHP 681

Query: 70  GPPPPGKPQGPP-PQGDKS----RSPRSPPGK-----PQGPP-PQGG-KPQGPPAQGGSK 117
           GP  P  PQGPP PQG         P+ PPG      PQGPP PQG   PQGPP      
Sbjct: 682 GPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPG----- 736

Query: 118 SQSARSPPGK--PQGPPQQEG----------NNPQGPPPPAGGNPQQPQAPPA-GQPQGP 164
           +Q  + PPG    QGPP   G            P    P  G NP+  Q PP   + QGP
Sbjct: 737 TQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQGP 796

Query: 165 PRPPQGGRPSRPPQ 178
              PQG     PPQ
Sbjct: 797 --APQGMIMGHPPQ 808



 Score = 76.3 bits (186), Expect = 1e-14
 Identities = 62/163 (38%), Positives = 67/163 (41%), Gaps = 36/163 (22%)

Query: 50  PPPPPGKPQ-GPPPQGGNKPQGPPPPGKPQGPP----PQGDKSRSPRSPPGKPQGPPPQG 104
           PPP  G P  GP P  G  P    P G  Q  P    P       P  P G+ + P PQG
Sbjct: 574 PPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQG 633

Query: 105 GK-PQGPPA-QGGSKSQSARSPPGKPQGPPQ-----QEGN---------------NPQGP 142
              PQGPP  QGG   Q    P G PQGPPQ     Q+ +                PQGP
Sbjct: 634 QMGPQGPPLHQGGGGPQGFMGPQG-PQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGP 692

Query: 143 PPPAGGNPQQ----PQAPPAGQ----PQGPPRPPQGGRPSRPP 177
           P P G +  Q    PQ PP  Q    PQGPP P     P  PP
Sbjct: 693 PGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPP 735



 Score = 72.8 bits (177), Expect = 1e-13
 Identities = 67/195 (34%), Positives = 78/195 (40%), Gaps = 55/195 (28%)

Query: 37  QGPSPQG---GNKPQ---GPPPPPGK----------------PQGPPPQGG--NKPQ--- 69
           QGP+PQG   G+ PQ   GP PP G                  QGPPPQG     PQ   
Sbjct: 794 QGPAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELR 853

Query: 70  GPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGKPQGP-PAQGGSKSQSARSP--PG 126
           GPP     QGPP QG     P+     P GP  Q    +GP P+QG    Q  ++P    
Sbjct: 854 GPPGSQSQQGPP-QGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGD 912

Query: 127 KPQGPPQQEGNNPQGPPPPAGG-------------NPQQPQAPPAGQPQGPP-------- 165
            P+ P  QEG +  GPPP   G             NP Q   P  G  +GPP        
Sbjct: 913 GPRAPFNQEGQS-TGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMS 971

Query: 166 --RPPQGGRPSRPPQ 178
             R  Q G P   P+
Sbjct: 972 ERRHEQSGGPEHGPE 986



 Score = 69.7 bits (169), Expect = 1e-12
 Identities = 64/163 (39%), Positives = 80/163 (49%), Gaps = 26/163 (15%)

Query: 29  PSLIAGNPQGPSPQGGNKPQGP--PPPPGKPQGPP-PQGGNKP-QGPPP-----PGKPQG 79
           P  + G P   S QG   PQG   PPP G  QGPP PQG   P +GP P     P + Q 
Sbjct: 849 PQELRGPPGSQSQQG--PPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQK 906

Query: 80  PPPQGDKSRSPRSPPGKPQGPPP--QGGKPQGPPAQGGSKSQSARSPPGKP-QGPPQQEG 136
            P  GD  R+P +  G+  GPPP   G   QG  AQG       R PP  P QGP   +G
Sbjct: 907 TPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQG--AQG-------RIPPLNPGQGPGPNKG 957

Query: 137 NNPQGPPPPAGGNPQQPQAPPAGQPQ-GPPRPP-QGGRPSRPP 177
           ++ +GPP    G   + +   +G P+ GP R P +GG+  R P
Sbjct: 958 DS-RGPPNHHMGPMSERRHEQSGGPEHGPERGPFRGGQDCRGP 999



 Score = 46.2 bits (108), Expect = 1e-05
 Identities = 56/195 (28%), Positives = 72/195 (36%), Gaps = 61/195 (31%)

Query: 25   QEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP-QGP-PP 82
            Q++   L+   P+ P  Q G     PP  PG  Q    QG    QG  PP  P QGP P 
Sbjct: 903  QQQKTPLLGDGPRAPFNQEGQSTGPPPLIPGLGQ----QGA---QGRIPPLNPGQGPGPN 955

Query: 83   QGDKSRSPRSPPGKPQGPPPQ------GGKPQGP---PAQGGSKSQSARSPPGKPQGP-- 131
            +GD     R PP    GP  +      GG   GP   P +GG   Q  R PP + +GP  
Sbjct: 956  KGDS----RGPPNHHMGPMSERRHEQSGGPEHGPERGPFRGG---QDCRGPPDR-RGPHP 1007

Query: 132  --------------------------------PQQEGNNPQGPPPPAGGNPQQ-PQAPPA 158
                                            PQ+E     GP PP   + ++  +    
Sbjct: 1008 DFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPPFPPDHREFSEGDGR 1067

Query: 159  GQPQGPPRPPQGGRP 173
            G  +GPP   +G RP
Sbjct: 1068 GAARGPPGAWEGRRP 1082



 Score = 37.0 bits (84), Expect = 0.009
 Identities = 47/186 (25%), Positives = 64/186 (34%), Gaps = 45/186 (24%)

Query: 20   NEDVSQEESPSL-IAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ 78
            N D S+E +    + G  +G +P+GG K   P P     + P  +GG KP       +P 
Sbjct: 1135 NFDASEEAARGRDLRGRGRG-TPRGGRKGLLPTPD----EFPRFEGGRKPDSWDGNREP- 1188

Query: 79   GPPPQGDKSRSPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQSARS-PPGK---------- 127
                 G      R  P +P  PP  G  P         +     S PP K          
Sbjct: 1189 -----GPGHEHFRDTP-RPDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGPGTS 1242

Query: 128  -------PQGPPQQEGNNPQGPPPPAGGNPQQPQA--------------PPAGQPQGPPR 166
                   P GP +  G   +G P PA   P+  ++               P G P G   
Sbjct: 1243 EHREMEAPGGPSEDRGGKGRGGPGPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGSGT 1302

Query: 167  PPQGGR 172
            P +GGR
Sbjct: 1303 PSRGGR 1308



 Score = 33.5 bits (75), Expect = 0.099
 Identities = 27/90 (30%), Positives = 34/90 (37%), Gaps = 9/90 (10%)

Query: 36   PQGPSPQGGNKPQGPPPPPGKPQGPPPQG------GNKPQGPPPPGKPQGPPPQGDKSRS 89
            P GPS   G K +G P P    Q  P  G      G    G        GPP  G  SR 
Sbjct: 1250 PGGPSEDRGGKGRGGPGPA---QRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGSGTPSRG 1306

Query: 90   PRSPPGKPQGPPPQGGKPQGPPAQGGSKSQ 119
             RS     +G     G P+   ++GG + +
Sbjct: 1307 GRSGSNWGRGSNMNSGPPRRGASRGGGRGR 1336



 Score = 27.3 bits (59), Expect = 7.1
 Identities = 28/124 (22%), Positives = 46/124 (37%), Gaps = 9/124 (7%)

Query: 35   NPQGPSPQGGNKPQGPPPPPGKPQG-PPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSP 93
            +P+ P  +G  +       P + +G  PP+G +   GP   G  +      + +R  R  
Sbjct: 1090 DPEDPRFRGRREESFRRGAPPRHEGRAPPRGRDGFPGPEDFGPEENFDASEEAARG-RDL 1148

Query: 94   PGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQP 153
             G+ +G P  G K   P      + +  R        P   +GN   GP      +  +P
Sbjct: 1149 RGRGRGTPRGGRKGLLPTPDEFPRFEGGRK-------PDSWDGNREPGPGHEHFRDTPRP 1201

Query: 154  QAPP 157
              PP
Sbjct: 1202 DHPP 1205


>gi|7706501 WW domain binding protein 11 [Homo sapiens]
          Length = 641

 Score = 85.5 bits (210), Expect = 2e-17
 Identities = 67/186 (36%), Positives = 79/186 (42%), Gaps = 33/186 (17%)

Query: 12  ALSSAQNLNEDVSQEESPSLIAGNPQGPSPQG--GNKPQGPPPPPGKPQGPPPQGGNKPQ 69
           A   +Q  +++ S  +  S  +   Q P PQ    ++ Q PP P   P GPPP    +P 
Sbjct: 366 AEKQSQKQHKEESHSDGTSTASSQQQAP-PQSVPPSQIQAPPMPGPPPLGPPPAPPLRPP 424

Query: 70  GPPPPGKPQGPPPQGDKSRSPRSPPG--------KPQGPPPQGGKPQGPPAQGGSKSQSA 121
           GPP  G P GPPP       P   PG         P GPPP  G+P GPP          
Sbjct: 425 GPPT-GLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPP--GRPPGPP---------P 472

Query: 122 RSPPGKPQGPPQQ------EGNNPQGPPPPAGGNPQQPQAPPAG-QPQG--PPRP-PQGG 171
             PPG P GPP +          P G PPP  G  + P  PP G  P G  PP P P  G
Sbjct: 473 GPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPG 532

Query: 172 RPSRPP 177
             S PP
Sbjct: 533 VLSAPP 538



 Score = 62.8 bits (151), Expect = 2e-10
 Identities = 46/123 (37%), Positives = 52/123 (42%), Gaps = 32/123 (26%)

Query: 57  PQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGKPQGPPAQGGS 116
           PQ  PP   ++ Q PP PG    PPP G     P  PPG P G PP  G P G P     
Sbjct: 394 PQSVPP---SQIQAPPMPG----PPPLGPPPAPPLRPPGPPTGLPP--GPPPGAP----- 439

Query: 117 KSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPP-RPPQGGRPSR 175
                  P  +P G P   G  P+  PP           PP G+P GPP  PP G  P  
Sbjct: 440 -------PFLRPPGMPGLRGPLPRLLPP----------GPPPGRPPGPPPGPPPGLPPGP 482

Query: 176 PPQ 178
           PP+
Sbjct: 483 PPR 485



 Score = 52.4 bits (124), Expect = 2e-07
 Identities = 38/112 (33%), Positives = 46/112 (41%), Gaps = 21/112 (18%)

Query: 36  PQGPSPQGGNKPQGPPP--PPGKPQGPPPQGGNKPQGPP-PPG--------------KPQ 78
           P GP P    +P GPPP  PPG P GPPP+G      PP PPG               P 
Sbjct: 459 PPGPPP---GRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPL 515

Query: 79  GPPPQGDKSRSPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSP-PGKPQ 129
           GP P G    +P   PG    PP    +P+       +  + A +    KPQ
Sbjct: 516 GPAPPGLFPPAPLPNPGVLSAPPNLIQRPKADDTSAATIEKKATATISAKPQ 567



 Score = 30.0 bits (66), Expect = 1.1
 Identities = 20/78 (25%), Positives = 30/78 (38%), Gaps = 2/78 (2%)

Query: 102 PQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQP 161
           P+ G+     ++   +  S  S   K      +E ++  G    +      PQ+ P  Q 
Sbjct: 343 PEEGREVEEFSEDDDEDDSDDSEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQI 402

Query: 162 QGPPR--PPQGGRPSRPP 177
           Q PP   PP  G P  PP
Sbjct: 403 QAPPMPGPPPLGPPPAPP 420



 Score = 28.9 bits (63), Expect = 2.4
 Identities = 26/88 (29%), Positives = 29/88 (32%), Gaps = 14/88 (15%)

Query: 52  PPPGKPQGPP-------PQGGNKPQGPPPPGKPQGPPPQGDKSRS------PRSPPG-KP 97
           P P  P  P        P  G +P          GPP +            PR PPG KP
Sbjct: 140 PLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKP 199

Query: 98  QGPPPQGGKPQGPPAQGGSKSQSARSPP 125
            GPPP    PQ     G     +   PP
Sbjct: 200 PGPPPGPPPPQVVQMYGRKVGFALDLPP 227



 Score = 28.5 bits (62), Expect = 3.2
 Identities = 18/50 (36%), Positives = 19/50 (38%), Gaps = 3/50 (6%)

Query: 36  PQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPP---PPGKPQGPPP 82
           P    P    K     PP       P  G   P+ PP   PPG P GPPP
Sbjct: 159 PGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPPP 208



 Score = 28.5 bits (62), Expect = 3.2
 Identities = 20/58 (34%), Positives = 22/58 (37%), Gaps = 11/58 (18%)

Query: 77  PQGPPPQGDKSRSPRSPPGKPQGPPPQ--GGKPQGPPAQGGSKSQSARSPPGKPQGPP 132
           P   PP   K  S   PP +     P    G P+ PP          R PPG P GPP
Sbjct: 159 PGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPG---------RKPPGPPPGPP 207



 Score = 28.1 bits (61), Expect = 4.1
 Identities = 17/35 (48%), Positives = 18/35 (51%), Gaps = 8/35 (22%)

Query: 29  PSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQ 63
           P L  G P+ P    G KP GPPP P     PPPQ
Sbjct: 184 PLLGHGVPRLPP---GRKPPGPPPGP-----PPPQ 210


>gi|19924099 synapsin I isoform Ia [Homo sapiens]
          Length = 705

 Score = 83.2 bits (204), Expect = 1e-16
 Identities = 58/149 (38%), Positives = 67/149 (44%), Gaps = 18/149 (12%)

Query: 36  PQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ----GPP---PQGDKSR 88
           P GP  Q    PQG PP PG   GP  QG    Q PPP G+      GPP   P   +  
Sbjct: 452 PAGPPAQQRPPPQGGPPQPGP--GPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLP 509

Query: 89  SPRSPPGKPQG---PPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPP 145
           SP S P +P     PP QG   Q  P  GG  +  A  PP  P   PQ++   PQ     
Sbjct: 510 SPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPS--PQRQAGPPQATRQT 567

Query: 146 AGGNPQQPQ---APPAGQP-QGPPRPPQG 170
           +   P  P+   APP GQ  QGPP+ P G
Sbjct: 568 SVSGPAPPKASGAPPGGQQRQGPPQKPPG 596



 Score = 77.4 bits (189), Expect = 6e-15
 Identities = 56/164 (34%), Positives = 63/164 (38%), Gaps = 23/164 (14%)

Query: 34  GNPQG-PSPQGGNKPQGPPPPPGKPQGPPPQGGNK--------PQGPP---PPGKP---- 77
           G P G P PQ    P   P  P     PP QG  +        P  PP   PP  P    
Sbjct: 497 GPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQR 556

Query: 78  QGPPPQGDKSRSPRSP-PGKPQGPPPQG----GKPQGPPAQGGSKSQSARSPPGKPQGPP 132
           Q  PPQ  +  S   P P K  G PP G    G PQ PP   G   Q++++ P    GPP
Sbjct: 557 QAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPP 616

Query: 133 QQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 176
             +   P GP P     PQ  Q P    P  PP     G P  P
Sbjct: 617 TTQQPRPSGPGPAGRPKPQLAQKPSQDVP--PPATAAAGGPPHP 658



 Score = 60.8 bits (146), Expect = 6e-10
 Identities = 52/139 (37%), Positives = 57/139 (41%), Gaps = 27/139 (19%)

Query: 53  PPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGKPQ---G 109
           P  + +   P  G+  Q P P   P G       S+ P  PP + Q PPPQGG PQ   G
Sbjct: 419 PRQRQRDASPGRGSHGQTPSPGALPLGR----QTSQQPAGPPAQ-QRPPPQGGPPQPGPG 473

Query: 110 PPAQGGSKSQSARSPP---------GKPQGPPQQEGNNPQGPPPPAGGNPQQP--QAPPA 158
           P  QG    Q  R PP         G P G P      PQ  P P    PQQP  QA P 
Sbjct: 474 PQRQGPPLQQ--RPPPQGQQHLSGLGPPAGSPL-----PQRLPSPTSA-PQQPASQAAPP 525

Query: 159 GQPQGPPRPPQGGRPSRPP 177
            Q QG    P  G P  PP
Sbjct: 526 TQGQGRQSRPVAGGPGAPP 544



 Score = 60.1 bits (144), Expect = 1e-09
 Identities = 44/145 (30%), Positives = 53/145 (36%), Gaps = 13/145 (8%)

Query: 21  EDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPP----PGKPQGPPPQGGNKPQGPPPPGK 76
           +  SQ   P+   G    P   G   P    PP    P +  GPP          P P K
Sbjct: 517 QPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPK 576

Query: 77  PQGPPPQGDKSRSPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQSAR----SPPGKPQGPP 132
             G PP G + + P   P  P GP  Q  +    P  G   +Q  R     P G+P+  P
Sbjct: 577 ASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPK--P 634

Query: 133 QQEGNNPQGPPPP---AGGNPQQPQ 154
           Q      Q  PPP   A G P  PQ
Sbjct: 635 QLAQKPSQDVPPPATAAAGGPPHPQ 659



 Score = 56.6 bits (135), Expect = 1e-08
 Identities = 51/141 (36%), Positives = 59/141 (41%), Gaps = 27/141 (19%)

Query: 36  PQGPSPQGGNKPQGPP----------PPPGKPQGPPPQGGNKPQGPP--PPGKPQGPPPQ 83
           P  PSPQ   +  GPP          P P K  G PP GG + QGPP  PPG P GP  Q
Sbjct: 549 PASPSPQ---RQAGPPQATRQTSVSGPAPPKASGAPP-GGQQRQGPPQKPPG-PAGPTRQ 603

Query: 84  GDKSRS-PRSPPGKPQGPPPQGGKPQGPP----AQGGSK-----SQSARSPPGKPQGPPQ 133
             ++   PR+ P   Q P P G  P G P    AQ  S+     + +A   P  PQ    
Sbjct: 604 ASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLNKS 663

Query: 134 QEGNNPQGPPPPAGGNPQQPQ 154
           Q   N    P PA   P   Q
Sbjct: 664 QSLTNAFNLPEPAPPRPSLSQ 684



 Score = 51.2 bits (121), Expect = 5e-07
 Identities = 42/126 (33%), Positives = 50/126 (39%), Gaps = 22/126 (17%)

Query: 28  SPSLIAGNPQ--------GPSPQ-------GGNKPQGPPPPPGKPQGP---PPQGGNKPQ 69
           SP   AG PQ        GP+P        GG + QGPP  P  P GP     Q G  P+
Sbjct: 553 SPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPR 612

Query: 70  GPPP---PGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPG 126
             PP     +P GP P G         P +   PPP      GPP    +KSQS  +   
Sbjct: 613 TGPPTTQQPRPSGPGPAGRPKPQLAQKPSQ-DVPPPATAAAGGPPHPQLNKSQSLTNAFN 671

Query: 127 KPQGPP 132
            P+  P
Sbjct: 672 LPEPAP 677



 Score = 31.6 bits (70), Expect = 0.38
 Identities = 15/42 (35%), Positives = 17/42 (40%), Gaps = 5/42 (11%)

Query: 46 KPQGPPPP-----PGKPQGPPPQGGNKPQGPPPPGKPQGPPP 82
          +PQ PPPP     PG   GP      +  G  P   P  P P
Sbjct: 27 RPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSP 68



 Score = 31.2 bits (69), Expect = 0.49
 Identities = 19/58 (32%), Positives = 22/58 (37%), Gaps = 5/58 (8%)

Query: 45  NKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPP 102
           N P G      +PQ PPP     P G   PG   GP     +  S  +P   P  P P
Sbjct: 16  NLPNGYMTDLQRPQPPPP-----PPGAHSPGATPGPGTATAERSSGVAPAASPAAPSP 68


>gi|19924097 synapsin I isoform Ib [Homo sapiens]
          Length = 669

 Score = 83.2 bits (204), Expect = 1e-16
 Identities = 58/149 (38%), Positives = 67/149 (44%), Gaps = 18/149 (12%)

Query: 36  PQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ----GPP---PQGDKSR 88
           P GP  Q    PQG PP PG   GP  QG    Q PPP G+      GPP   P   +  
Sbjct: 452 PAGPPAQQRPPPQGGPPQPGP--GPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLP 509

Query: 89  SPRSPPGKPQG---PPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPP 145
           SP S P +P     PP QG   Q  P  GG  +  A  PP  P   PQ++   PQ     
Sbjct: 510 SPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPS--PQRQAGPPQATRQT 567

Query: 146 AGGNPQQPQ---APPAGQP-QGPPRPPQG 170
           +   P  P+   APP GQ  QGPP+ P G
Sbjct: 568 SVSGPAPPKASGAPPGGQQRQGPPQKPPG 596



 Score = 77.4 bits (189), Expect = 6e-15
 Identities = 56/164 (34%), Positives = 63/164 (38%), Gaps = 23/164 (14%)

Query: 34  GNPQG-PSPQGGNKPQGPPPPPGKPQGPPPQGGNK--------PQGPP---PPGKP---- 77
           G P G P PQ    P   P  P     PP QG  +        P  PP   PP  P    
Sbjct: 497 GPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQR 556

Query: 78  QGPPPQGDKSRSPRSP-PGKPQGPPPQG----GKPQGPPAQGGSKSQSARSPPGKPQGPP 132
           Q  PPQ  +  S   P P K  G PP G    G PQ PP   G   Q++++ P    GPP
Sbjct: 557 QAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPP 616

Query: 133 QQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 176
             +   P GP P     PQ  Q P    P  PP     G P  P
Sbjct: 617 TTQQPRPSGPGPAGRPKPQLAQKPSQDVP--PPATAAAGGPPHP 658



 Score = 61.6 bits (148), Expect = 3e-10
 Identities = 47/155 (30%), Positives = 57/155 (36%), Gaps = 16/155 (10%)

Query: 21  EDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPP----PGKPQGPPPQGGNKPQGPPPPGK 76
           +  SQ   P+   G    P   G   P    PP    P +  GPP          P P K
Sbjct: 517 QPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPK 576

Query: 77  PQGPPPQGDKSRSPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQSAR----SPPGKPQGPP 132
             G PP G + + P   P  P GP  Q  +    P  G   +Q  R     P G+P+  P
Sbjct: 577 ASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPK--P 634

Query: 133 QQEGNNPQGPPPP---AGGNPQQPQ---APPAGQP 161
           Q      Q  PPP   A G P  PQ   +P   QP
Sbjct: 635 QLAQKPSQDVPPPATAAAGGPPHPQLKASPAQAQP 669



 Score = 60.8 bits (146), Expect = 6e-10
 Identities = 52/139 (37%), Positives = 57/139 (41%), Gaps = 27/139 (19%)

Query: 53  PPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGKPQ---G 109
           P  + +   P  G+  Q P P   P G       S+ P  PP + Q PPPQGG PQ   G
Sbjct: 419 PRQRQRDASPGRGSHGQTPSPGALPLGR----QTSQQPAGPPAQ-QRPPPQGGPPQPGPG 473

Query: 110 PPAQGGSKSQSARSPP---------GKPQGPPQQEGNNPQGPPPPAGGNPQQP--QAPPA 158
           P  QG    Q  R PP         G P G P      PQ  P P    PQQP  QA P 
Sbjct: 474 PQRQGPPLQQ--RPPPQGQQHLSGLGPPAGSPL-----PQRLPSPTSA-PQQPASQAAPP 525

Query: 159 GQPQGPPRPPQGGRPSRPP 177
            Q QG    P  G P  PP
Sbjct: 526 TQGQGRQSRPVAGGPGAPP 544



 Score = 31.6 bits (70), Expect = 0.38
 Identities = 15/42 (35%), Positives = 17/42 (40%), Gaps = 5/42 (11%)

Query: 46 KPQGPPPP-----PGKPQGPPPQGGNKPQGPPPPGKPQGPPP 82
          +PQ PPPP     PG   GP      +  G  P   P  P P
Sbjct: 27 RPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSP 68



 Score = 31.2 bits (69), Expect = 0.49
 Identities = 19/58 (32%), Positives = 22/58 (37%), Gaps = 5/58 (8%)

Query: 45  NKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPP 102
           N P G      +PQ PPP     P G   PG   GP     +  S  +P   P  P P
Sbjct: 16  NLPNGYMTDLQRPQPPPP-----PPGAHSPGATPGPGTATAERSSGVAPAASPAAPSP 68


>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
           sapiens]
          Length = 505

 Score = 80.5 bits (197), Expect = 7e-16
 Identities = 54/140 (38%), Positives = 55/140 (39%), Gaps = 24/140 (17%)

Query: 36  PQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSR-SPRSPP 94
           P  P P  G  P  PPPP      PPP  G     PPP   P   PP    SR S   PP
Sbjct: 277 PPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPP 336

Query: 95  GKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQ 154
                PPP    P  PPA   S      +P G P  PP   G  P  PPPP         
Sbjct: 337 -----PPPNRMYPPPPPALPSS------APSGPPPPPPSVLGVGPVAPPPP--------- 376

Query: 155 APPAGQPQGPPRPPQGGRPS 174
            PP   P GPP PP  G PS
Sbjct: 377 -PPPPPPPGPPPPP--GLPS 393



 Score = 79.7 bits (195), Expect = 1e-15
 Identities = 52/135 (38%), Positives = 56/135 (41%), Gaps = 26/135 (19%)

Query: 48  QGPPPPP---GKPQGPPPQGGNKPQGPPPP-----GKPQGPPPQGDKSRSPRSPPGKPQ- 98
           Q PPPPP   G P  PPP   N   GPPPP     G P  PP +   +  P  PP +P  
Sbjct: 275 QAPPPPPPSRGGPPPPPPPPHNS--GPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSV 332

Query: 99  ---GPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQA 155
               PPP    P  PPA   S      +P G P  PP   G  P  PPPP       P  
Sbjct: 333 AVPPPPPNRMYPPPPPALPSS------APSGPPPPPPSVLGVGPVAPPPPP------PPP 380

Query: 156 PPAGQPQGPPRPPQG 170
           PP G P  P  P  G
Sbjct: 381 PPPGPPPPPGLPSDG 395



 Score = 64.7 bits (156), Expect = 4e-11
 Identities = 39/110 (35%), Positives = 47/110 (42%), Gaps = 17/110 (15%)

Query: 71  PPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQG 130
           PPPP +   PPP          PP    GPPP   + +G P    S++ +A  PP     
Sbjct: 279 PPPPSRGGPPPP---------PPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPP----- 324

Query: 131 PPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQ---GGRPSRPP 177
           PP    +    PPPP    P  P A P+  P GPP PP    G  P  PP
Sbjct: 325 PPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPP 374



 Score = 54.7 bits (130), Expect = 4e-08
 Identities = 34/96 (35%), Positives = 39/96 (40%), Gaps = 16/96 (16%)

Query: 39  PSPQGGNKPQGPPPPPGKPQ-GPPPQGGNKPQGPPPPGK----PQGPPPQ-------GDK 86
           P P        PPPPP +P    PP   N+   PPPP      P GPPP        G  
Sbjct: 312 PPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPV 371

Query: 87  SRSPRSPPGKPQGPPPQGGKPQG----PPAQGGSKS 118
           +  P  PP  P GPPP  G P       P   G+K+
Sbjct: 372 APPPPPPPPPPPGPPPPPGLPSDGDHQVPTTAGNKA 407



 Score = 42.4 bits (98), Expect = 2e-04
 Identities = 21/51 (41%), Positives = 21/51 (41%), Gaps = 1/51 (1%)

Query: 128 PQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPP-RPPQGGRPSRPP 177
           P  PP   G  P  PPPP    P  P A   G P  PP R P    P  PP
Sbjct: 277 PPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPP 327



 Score = 42.0 bits (97), Expect = 3e-04
 Identities = 25/63 (39%), Positives = 29/63 (46%), Gaps = 7/63 (11%)

Query: 29  PSLIAGNPQGPSPQG----GNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG 84
           P+L +  P GP P      G  P  PPPPP     PPP G   P G P  G  Q P   G
Sbjct: 348 PALPSSAPSGPPPPPPSVLGVGPVAPPPPP---PPPPPPGPPPPPGLPSDGDHQVPTTAG 404

Query: 85  DKS 87
           +K+
Sbjct: 405 NKA 407



 Score = 40.4 bits (93), Expect = 8e-04
 Identities = 29/78 (37%), Positives = 30/78 (38%), Gaps = 22/78 (28%)

Query: 36  PQGPSPQGGNKPQGPPPPPG--KPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSP 93
           P  P     + P GPPPPP      GP       P  PPPP  P GPPP          P
Sbjct: 344 PPPPPALPSSAPSGPPPPPPSVLGVGPV-----APPPPPPPPPPPGPPP----------P 388

Query: 94  PGKP-----QGPPPQGGK 106
           PG P     Q P   G K
Sbjct: 389 PGLPSDGDHQVPTTAGNK 406



 Score = 39.7 bits (91), Expect = 0.001
 Identities = 21/59 (35%), Positives = 25/59 (42%), Gaps = 1/59 (1%)

Query: 117 KSQSARSPPGKPQG-PPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPS 174
           + Q+   PP    G PP     +  GPPPP       P  PP+  P   P PP   RPS
Sbjct: 273 RRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPS 331


>gi|57165375 glutamate receptor, ionotropic, N-methyl
           D-aspartate-associated protein 1 [Homo sapiens]
          Length = 371

 Score = 80.5 bits (197), Expect = 7e-16
 Identities = 57/120 (47%), Positives = 57/120 (47%), Gaps = 11/120 (9%)

Query: 50  PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPP--QGGKP 107
           PPP PG P GP P      Q PP PG P   PP      SP   PG P GP P  QGG P
Sbjct: 15  PPPNPGYPGGPQPPMPPYAQ-PPYPGAPYPQPPF---QPSPYGQPGYPHGPSPYPQGGYP 70

Query: 108 QGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPP--PAGGNPQ-QPQAPPAGQPQGP 164
           QGP  QGG   Q      G PQGP  Q G  PQGP P  P   NP  QPQ  P   P  P
Sbjct: 71  QGPYPQGGYP-QGPYPQEGYPQGPYPQ-GGYPQGPYPQSPFPPNPYGQPQVFPGQDPDSP 128



 Score = 76.6 bits (187), Expect = 1e-14
 Identities = 59/152 (38%), Positives = 67/152 (44%), Gaps = 22/152 (14%)

Query: 23  VSQEESPSLIAGNPQGPSPQGGNKPQGPPPP---PGKPQGPPPQGGNKPQGPPPPGKPQG 79
           +S E+S  +   N   P+P     PQ P PP   P  P  P PQ   +P     PG P G
Sbjct: 1   MSHEKSFLVSGDNYPPPNPGYPGGPQPPMPPYAQPPYPGAPYPQPPFQPSPYGQPGYPHG 60

Query: 80  PP--PQGDKSRSPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQE-- 135
           P   PQG   + P    G PQGP PQ G PQGP  QG           G PQGP  Q   
Sbjct: 61  PSPYPQGGYPQGPYPQGGYPQGPYPQEGYPQGPYPQG-----------GYPQGPYPQSPF 109

Query: 136 GNNPQGPPPPAGGNPQQPQAPPAG--QPQGPP 165
             NP G P    G  Q P +P  G  Q +GPP
Sbjct: 110 PPNPYGQPQVFPG--QDPDSPQHGNYQEEGPP 139



 Score = 63.9 bits (154), Expect = 7e-11
 Identities = 39/85 (45%), Positives = 43/85 (50%), Gaps = 6/85 (7%)

Query: 28  SPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKS 87
           SP    G PQGP PQGG  PQGP P  G PQGP PQGG  PQGP     PQ P P     
Sbjct: 62  SPYPQGGYPQGPYPQGGY-PQGPYPQEGYPQGPYPQGGY-PQGP----YPQSPFPPNPYG 115

Query: 88  RSPRSPPGKPQGPPPQGGKPQGPPA 112
           +    P   P  P     + +GPP+
Sbjct: 116 QPQVFPGQDPDSPQHGNYQEEGPPS 140



 Score = 38.5 bits (88), Expect = 0.003
 Identities = 29/81 (35%), Positives = 31/81 (38%), Gaps = 26/81 (32%)

Query: 100 PPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAP-PA 158
           PPP  G P GP                +P  PP  +      PP P    PQ P  P P 
Sbjct: 15  PPPNPGYPGGP----------------QPPMPPYAQ------PPYPGAPYPQPPFQPSPY 52

Query: 159 GQP---QGPPRPPQGGRPSRP 176
           GQP    GP   PQGG P  P
Sbjct: 53  GQPGYPHGPSPYPQGGYPQGP 73


>gi|57165373 glutamate receptor, ionotropic, N-methyl
           D-aspartate-associated protein 1 [Homo sapiens]
          Length = 371

 Score = 80.5 bits (197), Expect = 7e-16
 Identities = 57/120 (47%), Positives = 57/120 (47%), Gaps = 11/120 (9%)

Query: 50  PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPP--QGGKP 107
           PPP PG P GP P      Q PP PG P   PP      SP   PG P GP P  QGG P
Sbjct: 15  PPPNPGYPGGPQPPMPPYAQ-PPYPGAPYPQPPF---QPSPYGQPGYPHGPSPYPQGGYP 70

Query: 108 QGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPP--PAGGNPQ-QPQAPPAGQPQGP 164
           QGP  QGG   Q      G PQGP  Q G  PQGP P  P   NP  QPQ  P   P  P
Sbjct: 71  QGPYPQGGYP-QGPYPQEGYPQGPYPQ-GGYPQGPYPQSPFPPNPYGQPQVFPGQDPDSP 128



 Score = 76.6 bits (187), Expect = 1e-14
 Identities = 59/152 (38%), Positives = 67/152 (44%), Gaps = 22/152 (14%)

Query: 23  VSQEESPSLIAGNPQGPSPQGGNKPQGPPPP---PGKPQGPPPQGGNKPQGPPPPGKPQG 79
           +S E+S  +   N   P+P     PQ P PP   P  P  P PQ   +P     PG P G
Sbjct: 1   MSHEKSFLVSGDNYPPPNPGYPGGPQPPMPPYAQPPYPGAPYPQPPFQPSPYGQPGYPHG 60

Query: 80  PP--PQGDKSRSPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQE-- 135
           P   PQG   + P    G PQGP PQ G PQGP  QG           G PQGP  Q   
Sbjct: 61  PSPYPQGGYPQGPYPQGGYPQGPYPQEGYPQGPYPQG-----------GYPQGPYPQSPF 109

Query: 136 GNNPQGPPPPAGGNPQQPQAPPAG--QPQGPP 165
             NP G P    G  Q P +P  G  Q +GPP
Sbjct: 110 PPNPYGQPQVFPG--QDPDSPQHGNYQEEGPP 139



 Score = 63.9 bits (154), Expect = 7e-11
 Identities = 39/85 (45%), Positives = 43/85 (50%), Gaps = 6/85 (7%)

Query: 28  SPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKS 87
           SP    G PQGP PQGG  PQGP P  G PQGP PQGG  PQGP     PQ P P     
Sbjct: 62  SPYPQGGYPQGPYPQGGY-PQGPYPQEGYPQGPYPQGGY-PQGP----YPQSPFPPNPYG 115

Query: 88  RSPRSPPGKPQGPPPQGGKPQGPPA 112
           +    P   P  P     + +GPP+
Sbjct: 116 QPQVFPGQDPDSPQHGNYQEEGPPS 140



 Score = 38.5 bits (88), Expect = 0.003
 Identities = 29/81 (35%), Positives = 31/81 (38%), Gaps = 26/81 (32%)

Query: 100 PPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAP-PA 158
           PPP  G P GP                +P  PP  +      PP P    PQ P  P P 
Sbjct: 15  PPPNPGYPGGP----------------QPPMPPYAQ------PPYPGAPYPQPPFQPSPY 52

Query: 159 GQP---QGPPRPPQGGRPSRP 176
           GQP    GP   PQGG P  P
Sbjct: 53  GQPGYPHGPSPYPQGGYPQGP 73


>gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]
          Length = 502

 Score = 80.1 bits (196), Expect = 9e-16
 Identities = 51/132 (38%), Positives = 57/132 (43%), Gaps = 16/132 (12%)

Query: 46  KPQGPPPPPGKPQG----PPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPP 101
           +P  PPPPP +       PP  GGNK +  P P  P G  P          PP  P+GPP
Sbjct: 311 EPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAP----------PPPTPRGPP 360

Query: 102 PQG-GKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQ 160
           P G G P  PP     +S     PP    GPP      P  PPP +G  P  P  PPA  
Sbjct: 361 PPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALV 420

Query: 161 PQGPPRPPQGGR 172
           P G    P GGR
Sbjct: 421 PAG-GLAPGGGR 431



 Score = 70.1 bits (170), Expect = 1e-12
 Identities = 58/169 (34%), Positives = 64/169 (37%), Gaps = 45/169 (26%)

Query: 24  SQEESPSLIAGNP--QGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP 81
           +Q   P ++ GN    GP P     P G  PPP  P+GPPP G     GPPPP     PP
Sbjct: 324 NQLPRPPIVGGNKGRSGPLPP---VPLGIAPPPPTPRGPPPPGRG---GPPPP-----PP 372

Query: 82  PQGDKSRSPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQG 141
           P   +S  P  PP     PP  GG P  PP            PP  P  PP   GN P  
Sbjct: 373 PATGRS-GPLPPP-----PPGAGGPPMPPP------------PP--PPPPPPSSGNGPAP 412

Query: 142 PPPPAGGNPQQPQAPPAG------------QPQGPPRPPQGGRPSRPPQ 178
           PP P    P    AP  G            Q    P  P+      PPQ
Sbjct: 413 PPLPPALVPAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPPPQ 461



 Score = 63.5 bits (153), Expect = 9e-11
 Identities = 50/136 (36%), Positives = 56/136 (41%), Gaps = 44/136 (32%)

Query: 51  PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGKPQGP 110
           PPPP     PP +GGN+   PP  G        G+K RS   PP  P G  P    P+GP
Sbjct: 314 PPPP-----PPSRGGNQLPRPPIVG--------GNKGRSGPLPP-VPLGIAPPPPTPRGP 359

Query: 111 PAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGG--NPQQPQAPPAGQPQGPPRPP 168
           P            PPG+   PP         PPPPA G   P  P  P AG P  PP PP
Sbjct: 360 P------------PPGRGGPPP---------PPPPATGRSGPLPPPPPGAGGPPMPPPPP 398

Query: 169 -------QGGRPSRPP 177
                   G  P+ PP
Sbjct: 399 PPPPPPSSGNGPAPPP 414



 Score = 59.3 bits (142), Expect = 2e-09
 Identities = 38/113 (33%), Positives = 45/113 (39%), Gaps = 7/113 (6%)

Query: 36  PQGPSPQGGNKPQGPPPPP---GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRS 92
           P+GP P G   P  PPPP      P  PPP G   P  PPPP  P  PP  G+    P  
Sbjct: 356 PRGPPPPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPL 415

Query: 93  PPG--KPQGPPPQGGKPQ--GPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQG 141
           PP      G  P GG+        QG   +++  +P      PP Q      G
Sbjct: 416 PPALVPAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPPPQSSEGLVG 468



 Score = 46.2 bits (108), Expect = 1e-05
 Identities = 58/215 (26%), Positives = 74/215 (34%), Gaps = 75/215 (34%)

Query: 36  PQGPSPQGGNKPQGPPP---PPGKPQGPPPQG-----------------GNKPQGPPPPG 75
           P  P+P    +  G PP    PG  QG PP G                  ++ +G P PG
Sbjct: 160 PPPPTPANEERRGGLPPLPLHPGGDQGGPPVGPLSLGLATVDIQNPDITSSRYRGLPAPG 219

Query: 76  KPQGPPPQGDKSRSPRSPPGKPQGPP--------PQGG--------------------KP 107
                  +  K +  ++  G P G          PQ G                    + 
Sbjct: 220 PSPADKKRSGKKKISKADIGAPSGFKHVSHVGWDPQNGFDVNNLDPDLRSLFSRAGISEA 279

Query: 108 QGPPA------------QGGSKS---QSARSPPGKPQGPPQQEGNNPQGPPPP-AGGN-- 149
           Q   A            QGG ++   +  R  P  P  PP + GN  Q P PP  GGN  
Sbjct: 280 QLTDAETSKLIYDFIEDQGGLEAVRQEMRRQEPLPPPPPPSRGGN--QLPRPPIVGGNKG 337

Query: 150 ---PQQPQ----APPAGQPQGPPRPPQGGRPSRPP 177
              P  P     APP   P+GPP P +GG P  PP
Sbjct: 338 RSGPLPPVPLGIAPPPPTPRGPPPPGRGGPPPPPP 372



 Score = 33.5 bits (75), Expect = 0.099
 Identities = 29/97 (29%), Positives = 40/97 (41%), Gaps = 13/97 (13%)

Query: 42  QGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKS--------RSPRSP 93
           Q G++ Q PPPP   P     +GG  P    P G  QG PP G  S        ++P   
Sbjct: 152 QSGDRRQLPPPPT--PANEERRGGLPPLPLHPGGD-QGGPPVGPLSLGLATVDIQNPDIT 208

Query: 94  PGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQG 130
             + +G P  G  P      G  K + +++  G P G
Sbjct: 209 SSRYRGLPAPGPSPADKKRSG--KKKISKADIGAPSG 243



 Score = 28.5 bits (62), Expect = 3.2
 Identities = 16/42 (38%), Positives = 20/42 (47%), Gaps = 6/42 (14%)

Query: 133 QQEGNNPQGPPPPAGGNPQQ----PQAP--PAGQPQGPPRPP 168
           +Q G+  Q PPPP   N ++    P  P  P G   GPP  P
Sbjct: 151 RQSGDRRQLPPPPTPANEERRGGLPPLPLHPGGDQGGPPVGP 192


>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
          Length = 424

 Score = 79.7 bits (195), Expect = 1e-15
 Identities = 54/147 (36%), Positives = 60/147 (40%), Gaps = 5/147 (3%)

Query: 33  AGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRS 92
           AG P    P  G+    P PP G P     Q      GP   G P   PP       PR 
Sbjct: 278 AGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRP 337

Query: 93  PPGKPQ-GPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPP-PPAGGNP 150
           PPG P  GPPP G  P+GPP            P G    PP    +   GPP PP  G  
Sbjct: 338 PPGMPHPGPPPMGMPPRGPPFGSPMGHPGPMPPHGMRGPPPLMPPHGYTGPPRPPPYGYQ 397

Query: 151 QQPQAPPAGQPQGPPRPPQGGRPSRPP 177
           + P  PP   P+ PP PP+G  P R P
Sbjct: 398 RGPLPPPRPTPR-PPVPPRG--PLRGP 421



 Score = 75.5 bits (184), Expect = 2e-14
 Identities = 66/193 (34%), Positives = 68/193 (35%), Gaps = 46/193 (23%)

Query: 29  PSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQG----GNKPQGPPPPGKP----QGP 80
           P   A NP   S   G  P G PPP   P   PP G    G  P  PPPP  P     GP
Sbjct: 216 PPPSAPNPVVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPPAMPPPPMPPGAAGHGP 275

Query: 81  PPQGDKSRS----------PRSPPGKP-----------QGPPPQGGKPQGPPAQGGSKSQ 119
           P  G               P  P G P            GP   G    GPP  GG    
Sbjct: 276 PSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGG--QP 333

Query: 120 SARSPPGKPQGPPQQEGNNPQGPP-----------PPAGGNPQQPQAPPAGQPQGPPRPP 168
             R PPG P   P   G  P+GPP           PP G     P  PP G   GPPRPP
Sbjct: 334 PPRPPPGMPHPGPPPMGMPPRGPPFGSPMGHPGPMPPHGMRGPPPLMPPHGY-TGPPRPP 392

Query: 169 QGG---RPSRPPQ 178
             G    P  PP+
Sbjct: 393 PYGYQRGPLPPPR 405



 Score = 67.0 bits (162), Expect = 8e-12
 Identities = 54/168 (32%), Positives = 61/168 (36%), Gaps = 26/168 (15%)

Query: 31  LIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGN--KPQGPPPPGK-PQGPPPQGDKS 87
           L A NP   + +        PPPP  P       G+   P G PPPG  P   PP G  +
Sbjct: 195 LAAQNPLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPGMPPPGSFPPPVPPPG--A 252

Query: 88  RSPRSPPGKPQGPPPQGGKPQGPPAQG----GSKSQSARSPPGKPQGPPQQEG------- 136
             P  PP  P  P P G    GPP+ G    G        P   P G     G       
Sbjct: 253 LPPGIPPAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLA 312

Query: 137 -------NNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 177
                   +P   PP +GG P  P  PP G P  P  PP G  P  PP
Sbjct: 313 HHGPHGLGHPHAGPPGSGGQP--PPRPPPGMPH-PGPPPMGMPPRGPP 357



 Score = 63.2 bits (152), Expect = 1e-10
 Identities = 61/187 (32%), Positives = 67/187 (35%), Gaps = 49/187 (26%)

Query: 36  PQGPSPQGGNKPQGPPP---PPGKPQGPPPQG---GNKPQGPPPPGKP-QGPPPQGDKSR 88
           P G  P G   P  PPP   PPG P   PP     G    GPP  G P  G P  G    
Sbjct: 234 PPGMPPPGSFPPPVPPPGALPPGIPPAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHP 293

Query: 89  SP----------------------------RSPPGK----PQGPPPQGGKPQGPPAQGGS 116
            P                              PPG     P  PPP G    GPP  G  
Sbjct: 294 HPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPP-GMPHPGPPPMG-- 350

Query: 117 KSQSARSPP-GKPQG-PPQQEGNNPQGPPP--PAGGNPQQPQAPPAGQPQGPPRPPQ-GG 171
                R PP G P G P     +  +GPPP  P  G    P+ PP G  +GP  PP+   
Sbjct: 351 --MPPRGPPFGSPMGHPGPMPPHGMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPTP 408

Query: 172 RPSRPPQ 178
           RP  PP+
Sbjct: 409 RPPVPPR 415



 Score = 48.5 bits (114), Expect = 3e-06
 Identities = 39/107 (36%), Positives = 44/107 (41%), Gaps = 29/107 (27%)

Query: 34  GNPQGPSPQGGNKPQGPPPPPGKPQ-GPPPQG---------------GNKP----QGPPP 73
           G+P    P  G +P  P PPPG P  GPPP G               G  P    +GPPP
Sbjct: 320 GHPHAGPPGSGGQPP-PRPPPGMPHPGPPPMGMPPRGPPFGSPMGHPGPMPPHGMRGPPP 378

Query: 74  PGKPQG------PPPQGDKSRSPRSPP-GKPQGPPPQGGKPQGPPAQ 113
              P G      PPP G   R P  PP   P+ P P  G  +GP  Q
Sbjct: 379 LMPPHGYTGPPRPPPYG-YQRGPLPPPRPTPRPPVPPRGPLRGPLPQ 424



 Score = 33.5 bits (75), Expect = 0.099
 Identities = 22/56 (39%), Positives = 26/56 (46%), Gaps = 2/56 (3%)

Query: 29  PSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP-QGPPPQ 83
           P  + G P    P G   P  PPP  G  +GP P     P+ P PP  P +GP PQ
Sbjct: 370 PHGMRGPPPLMPPHGYTGPPRPPPY-GYQRGPLPPPRPTPRPPVPPRGPLRGPLPQ 424


>gi|48762934 alpha 2 type I collagen [Homo sapiens]
          Length = 1366

 Score = 79.3 bits (194), Expect = 2e-15
 Identities = 62/178 (34%), Positives = 76/178 (42%), Gaps = 18/178 (10%)

Query: 4   ILLSVALLALSSAQNLNEDVSQ-----EESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQ 58
           +LL    L L++ Q+L E+  +     +  P    G P  P   G + P GPP PPG P 
Sbjct: 10  LLLLAVTLCLATCQSLQEETVRKGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPG-PP 68

Query: 59  GPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGKPQGPPAQGGSKS 118
           GPP  GGN        G   GP P G     PR PPG    P PQG   QGP  + G   
Sbjct: 69  GPPGLGGNFAAQYDGKGVGLGPGPMG--LMGPRGPPGAAGAPGPQGF--QGPAGEPGEPG 124

Query: 119 QSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 176
           Q+  +    P GPP + G +  G P    G P +P       PQG    P  G P  P
Sbjct: 125 QTGPAGARGPAGPPGKAGED--GHP----GKPGRPGERGVVGPQGARGFP--GTPGLP 174



 Score = 65.5 bits (158), Expect = 2e-11
 Identities = 53/142 (37%), Positives = 57/142 (40%), Gaps = 19/142 (13%)

Query: 32  IAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPP-PPGKPQGPPPQGDKSRSP 90
           +AG    P P G N  QGPP P G       QGG   QGPP PPG    P P G     P
Sbjct: 515 LAGARGAPGPDGNNGAQGPPGPQG------VQGGKGEQGPPGPPGFQGLPGPSG-----P 563

Query: 91  RSPPGKP--QGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAG- 147
               GKP  +G   + G P GP    G +     S    P GP    G  P GPP P G 
Sbjct: 564 AGEVGKPGERGLHGEFGLP-GPAGPRGERGPPGESGAAGPTGPIGSRG--PSGPPGPDGN 620

Query: 148 -GNPQQPQAPPAGQPQGPPRPP 168
            G P    A     P GP   P
Sbjct: 621 KGEPGVVGAVGTAGPSGPSGLP 642



 Score = 63.9 bits (154), Expect = 7e-11
 Identities = 60/183 (32%), Positives = 71/183 (38%), Gaps = 27/183 (14%)

Query: 20  NEDVSQEESPSLIA-----GNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQG---- 70
           N D  +   P L+      G+P    P G   P G P   G+P    P G     G    
Sbjct: 435 NGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGF 494

Query: 71  PPPPGKPQGPPPQGDKSRS----PRSPPGKP-----QGPPP----QGGK-PQGPPAQGGS 116
           P P G    P   GDK  +     R  PG       QGPP     QGGK  QGPP   G 
Sbjct: 495 PGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGF 554

Query: 117 KSQSARSPPGKPQGPPQQEGNNPQ-GPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGR-PS 174
           +     S P    G P + G + + G P PAG  P+  + PP       P  P G R PS
Sbjct: 555 QGLPGPSGPAGEVGKPGERGLHGEFGLPGPAG--PRGERGPPGESGAAGPTGPIGSRGPS 612

Query: 175 RPP 177
            PP
Sbjct: 613 GPP 615



 Score = 57.4 bits (137), Expect = 6e-09
 Identities = 62/203 (30%), Positives = 68/203 (33%), Gaps = 70/203 (34%)

Query: 36  PQGPSPQGGNK-------PQGPPPPPGKPQGPPPQGGNKPQGPPPP----GKP------- 77
           P G   + GNK       PQGPP P G+     P G     GPP P    G P       
Sbjct: 350 PAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPG 409

Query: 78  -------QGPP-------------PQGDKSR-------SPRSPPGKPQGPPPQGGK-PQG 109
                   GPP             P GD  R        PR  PG P    P G + P G
Sbjct: 410 ADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVG 469

Query: 110 PPAQGGSKS----QSARSPPGK-----PQGPPQQEGNN----------PQGPPPPAGGN- 149
            P   G         AR  PG      P+GP    G N           +G P P G N 
Sbjct: 470 LPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNG 529

Query: 150 ---PQQPQAPPAGQ-PQGPPRPP 168
              P  PQ    G+  QGPP PP
Sbjct: 530 AQGPPGPQGVQGGKGEQGPPGPP 552



 Score = 55.5 bits (132), Expect = 2e-08
 Identities = 46/150 (30%), Positives = 56/150 (37%), Gaps = 12/150 (8%)

Query: 34  GNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSP 93
           GNP     +G     G P P G       +G     GP  P  P+G P  G++     + 
Sbjct: 667 GNPGRDGARGAPGAVGAPGPAG---ATGDRGEAGAAGPAGPAGPRGSP--GERGEVGPAG 721

Query: 94  PGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEG-NNPQGPPPPA-----G 147
           P    GP    G+P G   + G+K     +    P GP    G   P GPP PA     G
Sbjct: 722 PNGFAGPAGAAGQP-GAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDG 780

Query: 148 GNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 177
           G P     P A    GPP P     P  PP
Sbjct: 781 GPPGMTGFPGAAGRTGPPGPSGISGPPGPP 810



 Score = 54.7 bits (130), Expect = 4e-08
 Identities = 51/171 (29%), Positives = 64/171 (37%), Gaps = 35/171 (20%)

Query: 29  PSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKS- 87
           P+   G+     P G   P G   PPG P  P P+G     G   P  P G  P+G+   
Sbjct: 230 PAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAG--PRGEVGL 287

Query: 88  ---RSPRSPPGKPQGPPPQGGK----------------PQGPP----AQGGSKSQSARSP 124
                P  PPG P      G K                P+G P    A G + ++     
Sbjct: 288 PGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGE 347

Query: 125 PGKPQGPPQQEGN-------NPQGPPPPAGGNPQQPQAPPAGQPQGPPRPP 168
           PG P G   + GN        PQGPP P+G   ++     AG   GPP PP
Sbjct: 348 PG-PAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGS-AGPPGPP 396



 Score = 53.1 bits (126), Expect = 1e-07
 Identities = 49/157 (31%), Positives = 57/157 (36%), Gaps = 19/157 (12%)

Query: 33  AGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP-QGDKSRSPR 91
           AG    P P G + P GPP P GK     P+G   P G        GPP   G+K  S  
Sbjct: 792 AGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGE 851

Query: 92  SPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKP-----------QGPPQQEGNNPQ 140
           +    P G P   G    P   G   S+  R  PG              GPP   G    
Sbjct: 852 AGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARG---- 907

Query: 141 GPPPPAGGNPQQPQAP-PAGQPQGPPRPPQGGRPSRP 176
             PP A G+P    AP  AG+   P      GR  +P
Sbjct: 908 --PPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQP 942



 Score = 52.4 bits (124), Expect = 2e-07
 Identities = 47/159 (29%), Positives = 58/159 (36%), Gaps = 42/159 (26%)

Query: 36   PQGPSPQGGNK----PQGPPPPPGK--PQGPP-PQGGNKPQGPPPPGKPQGPPP------ 82
            P GP+ + GN+    P GP  P G   P+GP  PQG    +G P    P+G P       
Sbjct: 968  PVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNG 1027

Query: 83   ----------QGDKSRSPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPP 132
                       GD+       P  P+GP      P GP  + G         P   +GP 
Sbjct: 1028 LQGLPGIAGHHGDQGAPGSVGPAGPRGP----AGPSGPAGKDGRTGHPGTVGPAGIRGPQ 1083

Query: 133  QQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGG 171
              +G  P GPP P G             P GPP    GG
Sbjct: 1084 GHQG--PAGPPGPPG-------------PPGPPGVSGGG 1107



 Score = 51.6 bits (122), Expect = 4e-07
 Identities = 51/172 (29%), Positives = 60/172 (34%), Gaps = 30/172 (17%)

Query: 33  AGNPQGPS-PQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKS--RS 89
           A  P GP+ P G    +G   PPG    P   G   P GP     P GPP    K   R 
Sbjct: 761 AAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRG 820

Query: 90  PRSPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEG------------- 136
           PR   G P G   + G   GPP   G K  S  +    P G P  +G             
Sbjct: 821 PRGDQG-PVGRTGEVG-AVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGS 878

Query: 137 NNPQGPPPPAGGNPQQPQAPPAGQP--QGPP----------RPPQGGRPSRP 176
              +G P  AG   +      AG P  +GPP           P + GR   P
Sbjct: 879 RGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNP 930



 Score = 50.4 bits (119), Expect = 8e-07
 Identities = 49/151 (32%), Positives = 55/151 (36%), Gaps = 25/151 (16%)

Query: 41  PQGGNKPQGPPPPPGKP--------QGPPPQGG----NKPQGPPPPGKPQGPP-PQGDKS 87
           P G N   GP    G+P        +GP  + G      P G   P  P GPP P G  S
Sbjct: 719 PAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAG--S 776

Query: 88  RSPRSPPGKPQGP-------PPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGN-NP 139
           R    PPG    P       PP      GPP   G   +     P   QGP  + G    
Sbjct: 777 RGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGA 836

Query: 140 QGPPPPAGGNPQQPQAPPAGQPQGPPRPPQG 170
            GPP  AG      +A  AG P  P   PQG
Sbjct: 837 VGPPGFAGEKGPSGEAGTAGPPGTP--GPQG 865



 Score = 49.3 bits (116), Expect = 2e-06
 Identities = 49/156 (31%), Positives = 57/156 (36%), Gaps = 22/156 (14%)

Query: 34  GNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG----PPPQGDKSRS 89
           GNP      G     G P   G P  P P+G   P G       +G    P P G K  S
Sbjct: 298 GNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGES 357

Query: 90  P-RSPPGK--PQGPPPQGGK--PQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPP 144
             +  PG   PQGPP   G+   +GP  + GS           P GPP   G+      P
Sbjct: 358 GNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAG---------PPGPPGLRGSPGSRGLP 408

Query: 145 PAGGNPQQPQAPPAGQPQGPP--RPPQG--GRPSRP 176
            A G       P +    GP   R P G  GRP  P
Sbjct: 409 GADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEP 444



 Score = 49.3 bits (116), Expect = 2e-06
 Identities = 39/138 (28%), Positives = 51/138 (36%), Gaps = 12/138 (8%)

Query: 32   IAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGG-------NKPQGPPPPGKPQGPPPQG 84
            +AG    P P G   P G   PPG    P   G          P    PPG+   P  +G
Sbjct: 887  VAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKG 946

Query: 85   DKSRSPR-SPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPP 143
            ++       P G    P P G  P GP  + G++ ++  S P  P G     G  P GP 
Sbjct: 947  ERGYPGNIGPVGAAGAPGPHG--PVGPAGKHGNRGETGPSGPVGPAGAVGPRG--PSGPQ 1002

Query: 144  PPAGGNPQQPQAPPAGQP 161
               G   +  +  P G P
Sbjct: 1003 GIRGDKGEPGEKGPRGLP 1020



 Score = 48.9 bits (115), Expect = 2e-06
 Identities = 48/144 (33%), Positives = 57/144 (39%), Gaps = 11/144 (7%)

Query: 34   GNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSP 93
            GNP    P G +   G     G P    P G     G P P  P GP   G       + 
Sbjct: 928  GNPGNDGPPGRDGQPGHKGERGYPGNIGPVGA---AGAPGPHGPVGPA--GKHGNRGETG 982

Query: 94   PGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNP-QGPPPPAGGNPQQ 152
            P  P GP    G P+GP    G +          P+G P  +G+N  QG P  AG +  Q
Sbjct: 983  PSGPVGPAGAVG-PRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQ 1041

Query: 153  PQAPPAGQPQGPPRPPQGGRPSRP 176
              AP +  P G PR P G  PS P
Sbjct: 1042 -GAPGSVGPAG-PRGPAG--PSGP 1061



 Score = 48.5 bits (114), Expect = 3e-06
 Identities = 44/147 (29%), Positives = 52/147 (35%), Gaps = 23/147 (15%)

Query: 33   AGNPQGPSPQG------------GNKPQGPPPPPGKPQGPPPQGGNKPQGPP-PPGKPQG 79
            AG P  P PQG                +G P   G    P P G   P G   PPG    
Sbjct: 855  AGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGS 914

Query: 80   PPPQGDKSRSPRSPPGKPQGPPPQGGKP-----QGPPAQGGSKSQSARSPPGKPQGPPQQ 134
            P   G    + R       GPP + G+P     +G P   G    +    P  P GP  +
Sbjct: 915  PGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGK 974

Query: 135  EGN----NPQGPPPPAGG-NPQQPQAP 156
             GN     P GP  PAG   P+ P  P
Sbjct: 975  HGNRGETGPSGPVGPAGAVGPRGPSGP 1001



 Score = 48.1 bits (113), Expect = 4e-06
 Identities = 51/170 (30%), Positives = 62/170 (36%), Gaps = 35/170 (20%)

Query: 36  PQGPSPQGGNKP------QGPPPPPGKPQGPPPQGGNKPQGPP-------PPGKPQGPPP 82
           P+GP    G         QGP   PG+P    P G   P GPP        PGKP  P  
Sbjct: 98  PRGPPGAAG--APGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGE 155

Query: 83  QGDKS-RSPRSPPGKPQGPPPQG-----------GKPQGPPAQGGSKSQSARSPPGK--P 128
           +G    +  R  PG P  P  +G           G+P  P  +G   +      PG+   
Sbjct: 156 RGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGA 215

Query: 129 QGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQ--PQGPPRPPQGGRPSRP 176
           +G P + G    G P PAG         P G   P G   PP  G P  P
Sbjct: 216 RGLPGERGR--VGAPGPAGARGSDGSVGPVGPAGPIGSAGPP--GFPGAP 261



 Score = 47.4 bits (111), Expect = 7e-06
 Identities = 47/163 (28%), Positives = 60/163 (36%), Gaps = 37/163 (22%)

Query: 26   EESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPP------QGGNKPQGPP------- 72
            E  PS   G      P+G + PQG     G+P    P      +G N  QG P       
Sbjct: 980  ETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHG 1039

Query: 73   PPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGKPQGPPAQG--GSKSQSARSPPGKPQG 130
              G P    P G     PR P G P GP  + G+   P   G  G +       P  P G
Sbjct: 1040 DQGAPGSVGPAG-----PRGPAG-PSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAGPPG 1093

Query: 131  PPQQEGNNPQGPPPPAGG-----------NPQQPQAPPAGQPQ 162
            PP      P GPP  +GG              QP++ P+ +P+
Sbjct: 1094 PP-----GPPGPPGVSGGGYDFGYDGDFYRADQPRSAPSLRPK 1131



 Score = 47.0 bits (110), Expect = 9e-06
 Identities = 40/143 (27%), Positives = 47/143 (32%), Gaps = 14/143 (9%)

Query: 32  IAGNPQGPSPQGG---NKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSR 88
           + G P  P   G       +G P   G+   P P G     G   P  P GP        
Sbjct: 197 VKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGP-------I 249

Query: 89  SPRSPPGKPQGPPPQGG----KPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPP 144
               PPG P  P P+G        GP    G + +        P GPP   G N      
Sbjct: 250 GSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAK 309

Query: 145 PAGGNPQQPQAPPAGQPQGPPRP 167
            A G P    AP    P+G P P
Sbjct: 310 GAAGLPGVAGAPGLPGPRGIPGP 332



 Score = 41.6 bits (96), Expect = 4e-04
 Identities = 49/162 (30%), Positives = 59/162 (36%), Gaps = 36/162 (22%)

Query: 34  GNPQGPSPQGGNKPQGPPPPPGKPQGPPPQG----------GNKPQGPPPPGKPQGPPPQ 83
           G P  P  +G   PQG    PG P  P  +G            +P  P   G+P  P   
Sbjct: 148 GKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGEN 207

Query: 84  GDKSRS-PRSPP---GKPQGPPPQGGK-------PQGPPAQGGSKSQSARSPPGKPQGP- 131
           G   ++  R  P   G+   P P G +       P GP    GS       PPG P  P 
Sbjct: 208 GTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGS-----AGPPGFPGAPG 262

Query: 132 PQQE----GN-NPQGPPPPAGGNPQQPQAPPAGQPQGPPRPP 168
           P+ E    GN  P GP  P G    +   P    P GPP  P
Sbjct: 263 PKGEIGAVGNAGPAGPAGPRG----EVGLPGLSGPVGPPGNP 300


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score = 79.3 bits (194), Expect = 2e-15
 Identities = 62/165 (37%), Positives = 76/165 (46%), Gaps = 29/165 (17%)

Query: 26   EESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKP---QGPP-------PPG 75
            E  PS  AG P    P G + P+G P P G P  P P G   P    GPP        PG
Sbjct: 1313 ESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPG 1372

Query: 76   KPQGPPPQGDKSRSPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQSA-RSPPGK-----PQ 129
            +   P P G+    P  PPGK +GPP   G P+G   + G+K ++    PPGK     PQ
Sbjct: 1373 QTGSPGPTGEP--GPSGPPGK-RGPPGPAG-PEGRQGEKGAKGEAGLEGPPGKTGPIGPQ 1428

Query: 130  GPPQQEG-NNPQGPPPPAG-----GNPQQPQAPPAGQPQGPPRPP 168
            G P + G +  +G P P G     G+P  P  PP   P GPP  P
Sbjct: 1429 GAPGKPGPDGLRGIPGPVGEQGLPGSP-GPDGPPG--PMGPPGLP 1470



 Score = 75.5 bits (184), Expect = 2e-14
 Identities = 64/154 (41%), Positives = 78/154 (50%), Gaps = 27/154 (17%)

Query: 36   PQGPSPQGGNKPQ-GPPPPPGKPQGPP-PQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSP 93
            P G   + G+  Q GPP PPG P+GP    G + PQG  PPG    P   G+K     + 
Sbjct: 1235 PPGEKGETGDVGQMGPPGPPG-PRGPSGAPGADGPQG--PPGGIGNPGAVGEKGEPGEA- 1290

Query: 94   PGKPQGPPPQGGKPQGPPAQGGSKSQS----ARSPPGKPQGPPQQEGNNPQGPPPPAG-- 147
             G+P G P +GG P GP  + G K +S    A  PPG P+GPP  +G  P+G P P G  
Sbjct: 1291 -GEP-GLPGEGG-PPGPKGERGEKGESGPSGAAGPPG-PKGPPGDDG--PKGSPGPVGFP 1344

Query: 148  GNPQQPQAP-PAGQPQGPP-------RPPQGGRP 173
            G+P  P  P PAGQ  GPP        P Q G P
Sbjct: 1345 GDPGPPGEPGPAGQ-DGPPGDKGDDGEPGQTGSP 1377



 Score = 73.6 bits (179), Expect = 9e-14
 Identities = 63/190 (33%), Positives = 73/190 (38%), Gaps = 50/190 (26%)

Query: 32  IAGNPQGPSPQGGNKPQGPPPPPGKP-----------QGPPPQGGNKP------------ 68
           + G P    PQG    QGPP P GKP           +G P Q G K             
Sbjct: 581 LKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPG 640

Query: 69  ----QGPPPPGKPQGPP----PQGDKSR-SPRSPPGKP--------QGPPPQGGKPQGPP 111
               +G P P  P GPP     +GD     PR  PG+P        +GPP     P GPP
Sbjct: 641 EKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPG----PPGPP 696

Query: 112 AQGGSKSQSAR----SPPGKPQGPPQQEGN-NPQGPPPPAGGNPQQPQAPPAGQPQGPPR 166
              G   Q        P G+P GPP Q+GN   QG P P G      +  P G+P  P  
Sbjct: 697 GVTGMDGQPGPKGNVGPQGEP-GPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGM 755

Query: 167 PPQGGRPSRP 176
           P   G P  P
Sbjct: 756 PGADGPPGHP 765



 Score = 72.4 bits (176), Expect = 2e-13
 Identities = 61/162 (37%), Positives = 72/162 (44%), Gaps = 15/162 (9%)

Query: 22   DVSQEESPSLIAGNPQGPS-PQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPP-PGKPQG 79
            DV Q   P      P+GPS   G + PQGPP   G P     +G     G P  PG+   
Sbjct: 1244 DVGQMGPPG--PPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGP 1301

Query: 80   PPPQGDKSRSPRSPPGKPQGPPPQGGKPQGPPAQGGSK-SQSARSPPGKPQGPPQQEGNN 138
            P P+G++     S P    GPP     P+GPP   G K S      PG P GPP + G  
Sbjct: 1302 PGPKGERGEKGESGPSGAAGPPG----PKGPPGDDGPKGSPGPVGFPGDP-GPPGEPGPA 1356

Query: 139  PQ-GPPPPAG--GNPQQPQAP-PAGQPQGPPRPPQGGRPSRP 176
             Q GPP   G  G P Q  +P P G+P GP  PP    P  P
Sbjct: 1357 GQDGPPGDKGDDGEPGQTGSPGPTGEP-GPSGPPGKRGPPGP 1397



 Score = 71.6 bits (174), Expect = 3e-13
 Identities = 67/210 (31%), Positives = 79/210 (37%), Gaps = 58/210 (27%)

Query: 26   EESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPP-PQGGNKPQGPP-PPGKPQGPPPQ 83
            E  P  I G P      GG+ P GPP   G P GP  P G   P+GPP PPGK   P   
Sbjct: 920  ERGPRGITGKPGPKGNSGGDGPAGPPGERG-PNGPQGPTGFPGPKGPPGPPGKDGLPGHP 978

Query: 84   GDKSRS-------PRSPPGK--PQGPPPQGGK--------PQGPPAQGGSKSQSARS--- 123
            G +  +       P  PPG   PQGP  + G         P GPP + G    + +    
Sbjct: 979  GQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTK 1038

Query: 124  ----PPGKP--QGPPQQEG-------------------NNPQGPPPPAGGNPQQPQAPPA 158
                P G P   GPP   G                     P GPP PAG   ++  A  A
Sbjct: 1039 GDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAA 1098

Query: 159  GQ--------PQGPPRP--PQGGRPSRPPQ 178
            G         PQGPP P   +G    + PQ
Sbjct: 1099 GPIGIPGRPGPQGPPGPAGEKGAPGEKGPQ 1128



 Score = 70.5 bits (171), Expect = 7e-13
 Identities = 50/124 (40%), Positives = 61/124 (49%), Gaps = 22/124 (17%)

Query: 34  GNPQGPSPQGGNKPQGPPPPPGKPQ------GPPPQGGNKPQGPP-PPGKPQGPPPQG-D 85
           G P  P P+G   P+GPP PPG P        P P+G   PQG P PPG+   P  QG  
Sbjct: 673 GLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLP 732

Query: 86  KSRSPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKP--QGPPQQEGNNPQGPP 143
             +    PPG+ +GP  + G P  P A G         PPG P  +GPP ++G   QGPP
Sbjct: 733 GPQGAIGPPGE-KGPLGKPGLPGMPGADG---------PPGHPGKEGPPGEKGG--QGPP 780

Query: 144 PPAG 147
            P G
Sbjct: 781 GPQG 784



 Score = 70.1 bits (170), Expect = 1e-12
 Identities = 66/198 (33%), Positives = 78/198 (39%), Gaps = 58/198 (29%)

Query: 34   GNPQGPSPQGGNKPQGPPPPPGK--PQGPPPQGGNK-PQGPPPPGKPQGPPPQ-GDK--- 86
            G P  P PQG   P G    PG+  PQGP  + G + P G P P  P GPP + GDK   
Sbjct: 1102 GIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEI 1161

Query: 87   ----------SRSPRSPPGK--PQGPPPQGGKPQGPPAQGGSKSQSA----------RSP 124
                       +  + PPG   PQGP  Q G P G   + G + Q            R  
Sbjct: 1162 GEPGQKGSKGDKGEQGPPGPTGPQGPIGQPG-PSGADGEPGPRGQQGLFGQKGDEGPRGF 1220

Query: 125  PGKP--------QGPPQQEGN----NPQGPPPPAGGNPQQPQ-APPAGQPQGPP------ 165
            PG P         GPP ++G        GPP P G  P+ P  AP A  PQGPP      
Sbjct: 1221 PGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPG--PRGPSGAPGADGPQGPPGGIGNP 1278

Query: 166  -------RPPQGGRPSRP 176
                    P + G P  P
Sbjct: 1279 GAVGEKGEPGEAGEPGLP 1296



 Score = 69.7 bits (169), Expect = 1e-12
 Identities = 53/141 (37%), Positives = 63/141 (44%), Gaps = 19/141 (13%)

Query: 42   QGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP-PQGDK----SRSPRSPPGK 96
            +G   P GPP P G P    P G   P G P    PQGPP P G+K     + P+ P G+
Sbjct: 1074 KGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGR 1133

Query: 97   P--QGPP--PQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQ 152
               QGP   P    P GPP + G K +      G+P     +     QGPP P G  PQ 
Sbjct: 1134 DGLQGPVGLPGPAGPVGPPGEDGDKGEI-----GEPGQKGSKGDKGEQGPPGPTG--PQG 1186

Query: 153  P--QAPPAGQPQGP-PRPPQG 170
            P  Q  P+G    P PR  QG
Sbjct: 1187 PIGQPGPSGADGEPGPRGQQG 1207



 Score = 68.9 bits (167), Expect = 2e-12
 Identities = 59/146 (40%), Positives = 67/146 (45%), Gaps = 16/146 (10%)

Query: 33   AGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRS 92
            AG+P    P G   P G P  PG PQGPP   G K  G P    PQGP  + D  + P  
Sbjct: 1086 AGSPGERGPAGAAGPIGIPGRPG-PQGPPGPAGEK--GAPGEKGPQGPAGR-DGLQGPVG 1141

Query: 93   PPGK--PQGPPPQGGKPQ--GPPAQGGSK-SQSARSPPGK--PQGPPQQEG-NNPQGPPP 144
             PG   P GPP + G     G P Q GSK  +  + PPG   PQGP  Q G +   G P 
Sbjct: 1142 LPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPG 1201

Query: 145  PAGGN---PQQPQAPPAGQPQGPPRP 167
            P G      Q+    P G P GPP P
Sbjct: 1202 PRGQQGLFGQKGDEGPRGFP-GPPGP 1226



 Score = 68.9 bits (167), Expect = 2e-12
 Identities = 59/170 (34%), Positives = 71/170 (41%), Gaps = 31/170 (18%)

Query: 34   GNPQGPSPQGGNKPQGPPPPPGKPQGPPPQG-----GNK----PQGPPPPGKPQG----P 80
            G    P P G   P G P P G    P P+G     G K    P+G P P  P G    P
Sbjct: 1174 GEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLP 1233

Query: 81   PPQGDKSRS-------PRSPPGKPQGPP--PQGGKPQGPPAQGGSKSQSARSPPGKP--Q 129
             P G+K  +       P  PPG P+GP   P    PQGPP  GG  +  A    G+P   
Sbjct: 1234 GPPGEKGETGDVGQMGPPGPPG-PRGPSGAPGADGPQGPP--GGIGNPGAVGEKGEPGEA 1290

Query: 130  GPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQ--PQGPPRPPQGGRPSRPP 177
            G P   G    GPP P G   ++ ++ P+G   P GP  PP    P   P
Sbjct: 1291 GEPGLPGEG--GPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSP 1338



 Score = 66.6 bits (161), Expect = 1e-11
 Identities = 59/177 (33%), Positives = 68/177 (38%), Gaps = 40/177 (22%)

Query: 36   PQGPS-------PQGGNKPQGPPPPPGKPQ-----GPPPQGGNK----PQGPPPPGKPQG 79
            PQGP+       P G   P GP  PPG+       G P Q G+K     QGPP P  PQG
Sbjct: 1127 PQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQG 1186

Query: 80   P-----PPQGDKSRSPR------------SPPGKPQGPPPQG--GKPQGPPAQGGSKSQS 120
            P     P   D    PR             P G P  P P G  G P GPP + G     
Sbjct: 1187 PIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLP-GPPGEKGETGDV 1245

Query: 121  ARSPPGKPQGPPQQEG----NNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRP 173
             +  P  P GP    G    + PQGPP   G      +    G+   P  P +GG P
Sbjct: 1246 GQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPP 1302



 Score = 66.2 bits (160), Expect = 1e-11
 Identities = 52/145 (35%), Positives = 57/145 (39%), Gaps = 14/145 (9%)

Query: 34   GNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPP-PGKPQGPPPQGDKSRSPR- 91
            G P  P P G     GP    G P  P P G   P GPP  PG      P+G+K      
Sbjct: 1429 GAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLI 1488

Query: 92   ---SPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGG 148
                PPG+ QG     G P GP    G K +   + P  P GPP   G    GPP P G 
Sbjct: 1489 GLIGPPGE-QGEKGDRGLP-GPQGSSGPKGEQGITGPSGPIGPPGPPGL--PGPPGPKGA 1544

Query: 149  NPQQPQAPP---AGQPQ--GPPRPP 168
                    P   AG P   GPP PP
Sbjct: 1545 KGSSGPTGPKGEAGHPGPPGPPGPP 1569



 Score = 65.9 bits (159), Expect = 2e-11
 Identities = 54/160 (33%), Positives = 63/160 (39%), Gaps = 35/160 (21%)

Query: 34   GNPQGPSPQGGNKP------QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKS 87
            G P  P P+G   P      +GP    GKP      GG+ P GPP    P GP       
Sbjct: 901  GTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGP------- 953

Query: 88   RSPRSPPGK--PQGPPPQGGKPQGPPAQGGSKSQSARSPPGK-----PQGP-----PQQE 135
            + P   PG   P GPP + G P  P  +G +  Q    PPG      PQGP     P  E
Sbjct: 954  QGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGE 1013

Query: 136  GNNPQGPPPP--------AGGNPQQPQAPPAGQP--QGPP 165
              +P  P PP        AG    +    PAG P   GPP
Sbjct: 1014 RGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPP 1053



 Score = 63.9 bits (154), Expect = 7e-11
 Identities = 53/150 (35%), Positives = 61/150 (40%), Gaps = 20/150 (13%)

Query: 34   GNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP-PQGDKSRSPRS 92
            G P  P   G   P+G    PG P     +GG    G P P   +GP  P+G+  R PR 
Sbjct: 868  GVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGE--RGPRG 925

Query: 93   PPGKPQGPPPQGGK-PQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAG---- 147
              GKP      GG  P GPP + G         P  PQGP    G  P+GPP P G    
Sbjct: 926  ITGKPGPKGNSGGDGPAGPPGERG---------PNGPQGPTGFPG--PKGPPGPPGKDGL 974

Query: 148  -GNPQQPQAPPAGQPQGPPRPPQGGRPSRP 176
             G+P Q          GPP PP    P  P
Sbjct: 975  PGHPGQRGETGFQGKTGPPGPPGVVGPQGP 1004



 Score = 63.2 bits (152), Expect = 1e-10
 Identities = 61/192 (31%), Positives = 72/192 (37%), Gaps = 52/192 (27%)

Query: 34   GNPQGPSPQGGNKPQGPPPPPGKP-----------QGPPPQGGN-KPQGPPPPGKPQG-- 79
            G P    P G   P GP  P G+            +GPP + G   PQG P    P G  
Sbjct: 1381 GEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLR 1440

Query: 80   --PPPQGDK----SRSPRSPPGKPQGPP----------PQGGKPQ-------GPPAQGGS 116
              P P G++    S  P  PPG P GPP          P+G K         GPP + G 
Sbjct: 1441 GIPGPVGEQGLPGSPGPDGPPG-PMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGE 1499

Query: 117  KSQSARSPPGKPQGPPQQEG----NNPQGPPPPAG--GNPQQPQAPPAGQPQGP------ 164
            K       P    GP  ++G    + P GPP P G  G P    A  +  P GP      
Sbjct: 1500 KGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGH 1559

Query: 165  PRPPQGGRPSRP 176
            P PP  G P  P
Sbjct: 1560 PGPP--GPPGPP 1569



 Score = 60.1 bits (144), Expect = 1e-09
 Identities = 66/223 (29%), Positives = 78/223 (34%), Gaps = 83/223 (37%)

Query: 34  GNPQGPSPQGGNKPQGPPPPPGKPQGPPPQG--------------GNKPQ---------- 69
           G+P    P G    QGPP P G    P P+G              G K +          
Sbjct: 763 GHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDM 822

Query: 70  ---------GPPPPGKPQGPPPQGDKSRS-PRSPPGKPQGPPPQGGK------------- 106
                    GPP P    GP  +G K R  P   PG P GPP + GK             
Sbjct: 823 GIKGDRGEIGPPGPRGEDGP--EGPKGRGGPNGDPG-PLGPPGEKGKLGVPGLPGYPGRQ 879

Query: 107 -PQG----PPAQGGSKSQSARSPPGKP--------------------QGPPQQEGNN--- 138
            P+G    P   G +  +  R  PGKP                     G P  +GN+   
Sbjct: 880 GPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGD 939

Query: 139 -PQGPPPPAGGN-PQQPQAPPAGQPQGPPRPP-QGGRPSRPPQ 178
            P GPP   G N PQ P   P   P+GPP PP + G P  P Q
Sbjct: 940 GPAGPPGERGPNGPQGPTGFPG--PKGPPGPPGKDGLPGHPGQ 980



 Score = 58.9 bits (141), Expect = 2e-09
 Identities = 55/167 (32%), Positives = 65/167 (38%), Gaps = 32/167 (19%)

Query: 29  PSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQ---GPP----PPGKP---- 77
           P  + G    P P+G   PQG P PPG+   P  QG   PQ   GPP    P GKP    
Sbjct: 695 PPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPG 754

Query: 78  ----QGPPPQGDKSRSP-----RSPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKP 128
                GPP    K   P     + PPG PQGP    G P+G     G +           
Sbjct: 755 MPGADGPPGHPGKEGPPGEKGGQGPPG-PQGPIGYPG-PRGVKGADGIRGLKGTKGEKGE 812

Query: 129 QGPPQQEGN-------NPQGPPPPAG-GNPQQPQAPPAGQPQGPPRP 167
            G P  +G+          GPP P G   P+ P+    G P G P P
Sbjct: 813 DGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKG--RGGPNGDPGP 857



 Score = 58.2 bits (139), Expect = 4e-09
 Identities = 51/153 (33%), Positives = 60/153 (39%), Gaps = 21/153 (13%)

Query: 36   PQGPS----PQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPP-PPGKPQGPPPQGDKS-RS 89
            PQGP+    P G     GPP PPG+   P   G    +G P P G P    P G +    
Sbjct: 1001 PQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPG 1060

Query: 90   PRSPPGK-----------PQGPPPQGGKP--QGPPAQGGSKSQSARSPPGKPQGPPQQEG 136
             R  PG            P GPP   G P  +GP    G      R  P  P GP  ++G
Sbjct: 1061 DRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKG 1120

Query: 137  N-NPQGPPPPAGGNPQQPQAPPAGQPQGPPRPP 168
                +GP  PAG +  Q      G P GP  PP
Sbjct: 1121 APGEKGPQGPAGRDGLQGPVGLPG-PAGPVGPP 1152



 Score = 53.9 bits (128), Expect = 7e-08
 Identities = 44/131 (33%), Positives = 53/131 (40%), Gaps = 27/131 (20%)

Query: 34   GNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGP----PPPGK-----------PQ 78
            G P  P P G   P GPP  PG      P+G     G      PPG+           PQ
Sbjct: 1450 GLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQ 1509

Query: 79   GPP-PQGDKSRSPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGN 137
            G   P+G++  +  S P  P GPP       GPP   G+K  S       P GP  + G+
Sbjct: 1510 GSSGPKGEQGITGPSGPIGPPGPPGL----PGPPGPKGAKGSSG------PTGPKGEAGH 1559

Query: 138  -NPQGPPPPAG 147
              P GPP P G
Sbjct: 1560 PGPPGPPGPPG 1570



 Score = 48.1 bits (113), Expect = 4e-06
 Identities = 33/81 (40%), Positives = 39/81 (48%), Gaps = 9/81 (11%)

Query: 39   PSPQGGNKPQGPPPPPGKPQGPPPQGG----NKPQGPP-PPGKPQGPPPQGDK-SRSPRS 92
            P  QG    +G P P G   GP  + G    + P GPP PPG P  P P+G K S  P  
Sbjct: 1494 PGEQGEKGDRGLPGPQGS-SGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTG 1552

Query: 93   PPGKPQGPPPQGGKPQGPPAQ 113
            P G+   P P G  P GPP +
Sbjct: 1553 PKGEAGHPGPPG--PPGPPGE 1571



 Score = 47.8 bits (112), Expect = 5e-06
 Identities = 53/162 (32%), Positives = 62/162 (38%), Gaps = 18/162 (11%)

Query: 25  QEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPP-----PGKPQG 79
           Q+  P++I        P G   P G P PPG   GP  Q G+  +  PP     PG    
Sbjct: 454 QKGEPAIIEPGMLIEGPPGPEGPAGLPGPPG-TMGPTGQVGDPGERGPPGRPGLPGADGL 512

Query: 80  PPPQGDKSRSP-RSPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGN- 137
           P P G     P R   G   G   +G       +Q  +  Q AR     P GP    G  
Sbjct: 513 PGPPGTMLMLPFRFGGGGDAG--SKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRP 570

Query: 138 NPQGPPPPAG--GNPQQ--PQAPPAGQPQGPPRPPQGGRPSR 175
            P GPP   G  G P    PQ P     QGPP P   G+P R
Sbjct: 571 GPVGPPGSGGLKGEPGDVGPQGPRG--VQGPPGP--AGKPGR 608



 Score = 44.3 bits (103), Expect = 6e-05
 Identities = 28/77 (36%), Positives = 33/77 (42%), Gaps = 18/77 (23%)

Query: 39   PSPQGGNKPQG------------PPPPPGKPQGPPPQGGNKPQGPP-PPGKPQGPPPQGD 85
            P PQG + P+G            PP PPG P  P P+G     GP  P G+   P P G 
Sbjct: 1506 PGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPG- 1564

Query: 86   KSRSPRSPPGKPQGPPP 102
                P  PPG+   P P
Sbjct: 1565 ----PPGPPGEVIQPLP 1577



 Score = 36.6 bits (83), Expect = 0.012
 Identities = 44/155 (28%), Positives = 54/155 (34%), Gaps = 23/155 (14%)

Query: 35  NPQGPSPQGG-----------NKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQ 83
           NP  P+  G            +    P PPPG  +G     G   +            P 
Sbjct: 363 NPDQPTDPGAGAEIPTSTADTSNSSNPAPPPG--EGADDLEGEFTEETIRNLDENYYDPY 420

Query: 84  GDKSRSPRS-PPGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKP-QGPPQQEGNNPQG 141
            D + SP    PG P           GP  + G K + A   PG   +GPP  EG  P G
Sbjct: 421 YDPTSSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEG--PAG 478

Query: 142 PPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 176
            P P G      Q    G+ +GPP     GRP  P
Sbjct: 479 LPGPPGTMGPTGQVGDPGE-RGPP-----GRPGLP 507



 Score = 30.0 bits (66), Expect = 1.1
 Identities = 26/78 (33%), Positives = 35/78 (44%), Gaps = 7/78 (8%)

Query: 14   SSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNK-PQGPP 72
            SS     + ++    P    G P  P P G   P+G     G P GP  + G+  P GPP
Sbjct: 1511 SSGPKGEQGITGPSGPIGPPGPPGLPGPPG---PKGAKGSSG-PTGPKGEAGHPGPPGPP 1566

Query: 73   -PPGKPQGP-PPQGDKSR 88
             PPG+   P P Q  ++R
Sbjct: 1567 GPPGEVIQPLPIQASRTR 1584


>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
          Length = 1263

 Score = 78.6 bits (192), Expect = 3e-15
 Identities = 64/162 (39%), Positives = 67/162 (41%), Gaps = 30/162 (18%)

Query: 39  PSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPP--PPGKPQGPPP--QGDKSRSPRSPP 94
           P P  G+    PPPPP  P  PP  GG     PP  P G    PPP   GD +  P  PP
Sbjct: 589 PPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPP--PP 646

Query: 95  GKPQG---PPPQ---GGK--PQGPPAQGGSKSQSARSPP---------GKPQGPPQQEGN 137
             P+G   P P    GG   P  PP  G     SAR PP         G P  PP   G 
Sbjct: 647 PLPEGVGIPSPSSLPGGTAIPPPPPLPG-----SARIPPPPPPLPGSAGIPPPPPPLPGE 701

Query: 138 -NPQGPPPPAGGNPQQPQAPP-AGQPQGPPRPPQGGRPSRPP 177
                PPPP  G P  P  PP  G P  PP PP  G P  PP
Sbjct: 702 AGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPP 743



 Score = 74.3 bits (181), Expect = 5e-14
 Identities = 60/162 (37%), Positives = 61/162 (37%), Gaps = 23/162 (14%)

Query: 29  PSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSR 88
           PS     P  P P        PPP PG    PPP        PPPP  P  P P G    
Sbjct: 568 PSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPP--------PPPPPPPPPPLPGGVCIS 619

Query: 89  SPRSPPGKP--QGPPPQGGK---PQGPPAQGGSKSQSARSPPGK---PQGPPQQEGNNPQ 140
           SP S PG      PPP  G    P  PP   G    S  S PG    P  PP        
Sbjct: 620 SPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIP 679

Query: 141 GPPPPAGGNPQQPQAPP-----AGQPQGPPRPPQGGRPSRPP 177
            PPPP  G+   P  PP     AG P  PP PP  G P  PP
Sbjct: 680 PPPPPLPGSAGIPPPPPPLPGEAGMP--PPPPPLPGGPGIPP 719



 Score = 65.1 bits (157), Expect = 3e-11
 Identities = 55/155 (35%), Positives = 58/155 (37%), Gaps = 31/155 (20%)

Query: 29  PSLIAGNPQGPSPQGGNKPQGPPPPPGKPQG---PPPQ---GGNKPQGPPP-PGKPQGPP 81
           PSL  G    P P        PPPPP  P+G   P P    GG     PPP PG  + PP
Sbjct: 622 PSLPGGTAISPPPPLSGDATIPPPPP-LPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPP 680

Query: 82  PQGDKSRSPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQG 141
           P      S   PP  P  P   G  P  PP  GG         PG P             
Sbjct: 681 PPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGG---------PGIP------------- 718

Query: 142 PPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 176
           PPPP  G P  P  PP G    PP P   G P+ P
Sbjct: 719 PPPPFPGGPGIP-PPPPGMGMPPPPPFGFGVPAAP 752



 Score = 56.2 bits (134), Expect = 1e-08
 Identities = 47/133 (35%), Positives = 49/133 (36%), Gaps = 37/133 (27%)

Query: 28  SPSLIAGN----PQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQ 83
           SPS + G     P  P P     P  PPP PG    PPP        PP PG+   PPP 
Sbjct: 656 SPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPP-------PPLPGEAGMPPP- 707

Query: 84  GDKSRSPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPP 143
                    PP  P GP    G P  PP  GG         PG P  PP   G     PP
Sbjct: 708 ---------PPPLPGGP----GIPPPPPFPGG---------PGIPPPPP---GMGMPPPP 742

Query: 144 PPAGGNPQQPQAP 156
           P   G P  P  P
Sbjct: 743 PFGFGVPAAPVLP 755



 Score = 51.2 bits (121), Expect = 5e-07
 Identities = 37/117 (31%), Positives = 40/117 (34%), Gaps = 7/117 (5%)

Query: 68  PQGPPPPGKPQGPPPQGDKSR---SPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSP 124
           P  P     P  PP  GD       P +P      PPP    P  PP  GG    S  S 
Sbjct: 565 PSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSL 624

Query: 125 PG----KPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 177
           PG     P  P   +   P  PP P G     P + P G    PP P  G     PP
Sbjct: 625 PGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPP 681



 Score = 45.8 bits (107), Expect = 2e-05
 Identities = 42/125 (33%), Positives = 44/125 (35%), Gaps = 35/125 (28%)

Query: 53  PPGKPQGPPPQGGNKPQGPPPPGKPQG---PPPQGDKSRSPRSPPGKPQGPPPQGGKPQG 109
           PP  P   P      P  PP PG       PPP    S +P  PP  P  PPP       
Sbjct: 564 PPSVPSRAPV-----PPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPP--PPP------- 609

Query: 110 PPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQ 169
           PP  GG    S          PP   G     PPPP  G+   P  PP      PP P  
Sbjct: 610 PPLPGGVCISS----------PPSLPGGTAISPPPPLSGDATIP--PP------PPLPEG 651

Query: 170 GGRPS 174
            G PS
Sbjct: 652 VGIPS 656



 Score = 28.1 bits (61), Expect = 4.1
 Identities = 16/48 (33%), Positives = 17/48 (35%), Gaps = 2/48 (4%)

Query: 131 PPQQEGNNPQGPPPPAGGNPQQ--PQAPPAGQPQGPPRPPQGGRPSRP 176
           PP      P  P PP  G+     P  P  G    PP PP    P  P
Sbjct: 564 PPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPP 611


>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
          Length = 1272

 Score = 78.6 bits (192), Expect = 3e-15
 Identities = 64/162 (39%), Positives = 67/162 (41%), Gaps = 30/162 (18%)

Query: 39  PSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPP--PPGKPQGPPP--QGDKSRSPRSPP 94
           P P  G+    PPPPP  P  PP  GG     PP  P G    PPP   GD +  P  PP
Sbjct: 598 PPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPP--PP 655

Query: 95  GKPQG---PPPQ---GGK--PQGPPAQGGSKSQSARSPP---------GKPQGPPQQEGN 137
             P+G   P P    GG   P  PP  G     SAR PP         G P  PP   G 
Sbjct: 656 PLPEGVGIPSPSSLPGGTAIPPPPPLPG-----SARIPPPPPPLPGSAGIPPPPPPLPGE 710

Query: 138 -NPQGPPPPAGGNPQQPQAPP-AGQPQGPPRPPQGGRPSRPP 177
                PPPP  G P  P  PP  G P  PP PP  G P  PP
Sbjct: 711 AGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPP 752



 Score = 74.3 bits (181), Expect = 5e-14
 Identities = 60/162 (37%), Positives = 61/162 (37%), Gaps = 23/162 (14%)

Query: 29  PSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSR 88
           PS     P  P P        PPP PG    PPP        PPPP  P  P P G    
Sbjct: 577 PSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPP--------PPPPPPPPPPLPGGVCIS 628

Query: 89  SPRSPPGKP--QGPPPQGGK---PQGPPAQGGSKSQSARSPPGK---PQGPPQQEGNNPQ 140
           SP S PG      PPP  G    P  PP   G    S  S PG    P  PP        
Sbjct: 629 SPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIP 688

Query: 141 GPPPPAGGNPQQPQAPP-----AGQPQGPPRPPQGGRPSRPP 177
            PPPP  G+   P  PP     AG P  PP PP  G P  PP
Sbjct: 689 PPPPPLPGSAGIPPPPPPLPGEAGMP--PPPPPLPGGPGIPP 728



 Score = 65.1 bits (157), Expect = 3e-11
 Identities = 55/155 (35%), Positives = 58/155 (37%), Gaps = 31/155 (20%)

Query: 29  PSLIAGNPQGPSPQGGNKPQGPPPPPGKPQG---PPPQ---GGNKPQGPPP-PGKPQGPP 81
           PSL  G    P P        PPPPP  P+G   P P    GG     PPP PG  + PP
Sbjct: 631 PSLPGGTAISPPPPLSGDATIPPPPP-LPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPP 689

Query: 82  PQGDKSRSPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQG 141
           P      S   PP  P  P   G  P  PP  GG         PG P             
Sbjct: 690 PPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGG---------PGIP------------- 727

Query: 142 PPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 176
           PPPP  G P  P  PP G    PP P   G P+ P
Sbjct: 728 PPPPFPGGPGIP-PPPPGMGMPPPPPFGFGVPAAP 761



 Score = 56.2 bits (134), Expect = 1e-08
 Identities = 47/133 (35%), Positives = 49/133 (36%), Gaps = 37/133 (27%)

Query: 28  SPSLIAGN----PQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQ 83
           SPS + G     P  P P     P  PPP PG    PPP        PP PG+   PPP 
Sbjct: 665 SPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPP-------PPLPGEAGMPPP- 716

Query: 84  GDKSRSPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPP 143
                    PP  P GP    G P  PP  GG         PG P  PP   G     PP
Sbjct: 717 ---------PPPLPGGP----GIPPPPPFPGG---------PGIPPPPP---GMGMPPPP 751

Query: 144 PPAGGNPQQPQAP 156
           P   G P  P  P
Sbjct: 752 PFGFGVPAAPVLP 764



 Score = 51.2 bits (121), Expect = 5e-07
 Identities = 37/117 (31%), Positives = 40/117 (34%), Gaps = 7/117 (5%)

Query: 68  PQGPPPPGKPQGPPPQGDKSR---SPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSP 124
           P  P     P  PP  GD       P +P      PPP    P  PP  GG    S  S 
Sbjct: 574 PSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSL 633

Query: 125 PG----KPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 177
           PG     P  P   +   P  PP P G     P + P G    PP P  G     PP
Sbjct: 634 PGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPP 690



 Score = 45.8 bits (107), Expect = 2e-05
 Identities = 42/125 (33%), Positives = 44/125 (35%), Gaps = 35/125 (28%)

Query: 53  PPGKPQGPPPQGGNKPQGPPPPGKPQG---PPPQGDKSRSPRSPPGKPQGPPPQGGKPQG 109
           PP  P   P      P  PP PG       PPP    S +P  PP  P  PPP       
Sbjct: 573 PPSVPSRAPV-----PPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPP--PPP------- 618

Query: 110 PPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQ 169
           PP  GG    S          PP   G     PPPP  G+   P  PP      PP P  
Sbjct: 619 PPLPGGVCISS----------PPSLPGGTAISPPPPLSGDATIP--PP------PPLPEG 660

Query: 170 GGRPS 174
            G PS
Sbjct: 661 VGIPS 665



 Score = 28.1 bits (61), Expect = 4.1
 Identities = 16/48 (33%), Positives = 17/48 (35%), Gaps = 2/48 (4%)

Query: 131 PPQQEGNNPQGPPPPAGGNPQQ--PQAPPAGQPQGPPRPPQGGRPSRP 176
           PP      P  P PP  G+     P  P  G    PP PP    P  P
Sbjct: 573 PPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPP 620


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score = 78.2 bits (191), Expect = 3e-15
 Identities = 55/147 (37%), Positives = 56/147 (38%), Gaps = 6/147 (4%)

Query: 36   PQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPP- 94
            P  P P  G  P  P P  G P  PP  G   P  PP PG    PPP    +  P  PP 
Sbjct: 988  PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1047

Query: 95   ---GKPQGPP-PQGGKPQGPPAQGGSKSQSARSP-PGKPQGPPQQEGNNPQGPPPPAGGN 149
               G P  PP P  G P  PP  G         P  G P  PP      P  PP P  G 
Sbjct: 1048 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGI 1107

Query: 150  PQQPQAPPAGQPQGPPRPPQGGRPSRP 176
            P  P  P AG P  PP P  G  P  P
Sbjct: 1108 PPPPPLPGAGIPPPPPLPGAGIPPPPP 1134



 Score = 78.2 bits (191), Expect = 3e-15
 Identities = 55/147 (37%), Positives = 56/147 (38%), Gaps = 6/147 (4%)

Query: 36   PQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPP- 94
            P  P P  G  P  P P  G P  PP  G   P  PP PG    PPP    +  P  PP 
Sbjct: 999  PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1058

Query: 95   ---GKPQGPP-PQGGKPQGPPAQGGSKSQSARSP-PGKPQGPPQQEGNNPQGPPPPAGGN 149
               G P  PP P  G P  PP  G         P  G P  PP      P  PP P  G 
Sbjct: 1059 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGI 1118

Query: 150  PQQPQAPPAGQPQGPPRPPQGGRPSRP 176
            P  P  P AG P  PP P  G  P  P
Sbjct: 1119 PPPPPLPGAGIPPPPPLPGAGIPPPPP 1145



 Score = 77.8 bits (190), Expect = 5e-15
 Identities = 57/151 (37%), Positives = 58/151 (38%), Gaps = 7/151 (4%)

Query: 33   AGNPQGPSPQGGNKPQGPP-PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPR 91
            AG P  P   G   P  PP P  G P  PP  G   P  PP PG    PPP    +  P 
Sbjct: 962  AGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1021

Query: 92   SPP----GKPQGPP-PQGGKPQGPPAQGGSKSQSARSP-PGKPQGPPQQEGNNPQGPPPP 145
             PP    G P  PP P  G P  PP  G         P  G P  PP      P  PP P
Sbjct: 1022 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1081

Query: 146  AGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 176
              G P  P  P AG P  PP P  G  P  P
Sbjct: 1082 GAGIPPPPPLPGAGIPPPPPLPGVGIPPPPP 1112



 Score = 77.8 bits (190), Expect = 5e-15
 Identities = 54/147 (36%), Positives = 55/147 (37%), Gaps = 6/147 (4%)

Query: 36   PQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPP- 94
            P  P P  G  P  P P  G P  PP  G   P  PP PG    PPP    +  P  PP 
Sbjct: 977  PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1036

Query: 95   ---GKPQGPP-PQGGKPQGPPAQGGSKSQSARSP-PGKPQGPPQQEGNNPQGPPPPAGGN 149
               G P  PP P  G P  PP  G         P  G P  PP      P  PP P  G 
Sbjct: 1037 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1096

Query: 150  PQQPQAPPAGQPQGPPRPPQGGRPSRP 176
            P  P  P  G P  PP P  G  P  P
Sbjct: 1097 PPPPPLPGVGIPPPPPLPGAGIPPPPP 1123



 Score = 77.4 bits (189), Expect = 6e-15
 Identities = 57/151 (37%), Positives = 58/151 (38%), Gaps = 7/151 (4%)

Query: 33   AGNPQGPSPQGGNKPQGPP-PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPR 91
            AG P  P   G   P  PP P  G P  PP  G   P  PP PG    PPP    +  P 
Sbjct: 940  AGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 999

Query: 92   SPP----GKPQGPP-PQGGKPQGPPAQGGSKSQSARSP-PGKPQGPPQQEGNNPQGPPPP 145
             PP    G P  PP P  G P  PP  G         P  G P  PP      P  PP P
Sbjct: 1000 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1059

Query: 146  AGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 176
              G P  P  P AG P  PP P  G  P  P
Sbjct: 1060 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1090



 Score = 77.0 bits (188), Expect = 8e-15
 Identities = 57/149 (38%), Positives = 58/149 (38%), Gaps = 10/149 (6%)

Query: 36   PQGPSPQGGNKPQGPPPPPGKPQGPPPQ--GGNKPQGPPPPGKPQGPPPQGDKSRSPRSP 93
            P  P P  G  P  PPP PG    PPP   G   P  PP PG    PPP    +  P  P
Sbjct: 933  PLPPLPGAGIPP--PPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPP 990

Query: 94   P----GKPQGPP-PQGGKPQGPPAQGGSKSQSARSP-PGKPQGPPQQEGNNPQGPPPPAG 147
            P    G P  PP P  G P  PP  G         P  G P  PP      P  PP P  
Sbjct: 991  PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 1050

Query: 148  GNPQQPQAPPAGQPQGPPRPPQGGRPSRP 176
            G P  P  P AG P  PP P  G  P  P
Sbjct: 1051 GIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1079



 Score = 77.0 bits (188), Expect = 8e-15
 Identities = 57/149 (38%), Positives = 58/149 (38%), Gaps = 10/149 (6%)

Query: 36   PQGPSPQGGNKPQGPPPPPGK--PQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSP 93
            P  P P  G  P  PPP PG   P  PP  G   P  PP PG    PPP    +  P  P
Sbjct: 1010 PPPPLPGAGIPP--PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1067

Query: 94   P----GKPQGPP-PQGGKPQGPPAQGGSKSQSARSP-PGKPQGPPQQEGNNPQGPPPPAG 147
            P    G P  PP P  G P  PP  G         P  G P  PP      P  PP P  
Sbjct: 1068 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGA 1127

Query: 148  GNPQQPQAPPAGQPQGPPRPPQGGRPSRP 176
            G P  P  P AG P  PP P  G  P  P
Sbjct: 1128 GIPPPPPLPGAGIPPPPPLPRVGIPPPPP 1156



 Score = 77.0 bits (188), Expect = 8e-15
 Identities = 57/149 (38%), Positives = 58/149 (38%), Gaps = 10/149 (6%)

Query: 36   PQGPSPQGGNKPQGPPPPPGK--PQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSP 93
            P  P P  G  P  PPP PG   P  PP  G   P  PP PG    PPP    +  P  P
Sbjct: 1043 PPPPLPGAGIPP--PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1100

Query: 94   P----GKPQGPP-PQGGKPQGPPAQGGSKSQSARSP-PGKPQGPPQQEGNNPQGPPPPAG 147
            P    G P  PP P  G P  PP  G         P  G P  PP      P  PP P  
Sbjct: 1101 PLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGA 1160

Query: 148  GNPQQPQAPPAGQPQGPPRPPQGGRPSRP 176
            G P  P  P AG P  PP P  G  P  P
Sbjct: 1161 GIPPPPPLPGAGIPPPPPLPGVGIPPPPP 1189



 Score = 76.6 bits (187), Expect = 1e-14
 Identities = 55/148 (37%), Positives = 58/148 (39%), Gaps = 6/148 (4%)

Query: 36   PQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPP- 94
            P  P P  G  P  P P  G P  PP  G   P  PP PG    PPP    +  P  PP 
Sbjct: 1076 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1135

Query: 95   ---GKPQGPP-PQGGKPQGPPAQGGSKSQSARSP-PGKPQGPPQQEGNNPQGPPPPAGGN 149
               G P  PP P+ G P  PP  G         P  G P  PP      P  PP P  G 
Sbjct: 1136 PGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGI 1195

Query: 150  PQQPQAPPAGQPQGPPRPPQGGRPSRPP 177
            P  P  P AG P  PP P  G  P+  P
Sbjct: 1196 PPPPPLPGAGIPPPPPLPGMGIPPAPAP 1223



 Score = 75.9 bits (185), Expect = 2e-14
 Identities = 56/151 (37%), Positives = 57/151 (37%), Gaps = 7/151 (4%)

Query: 33   AGNPQGPSPQGGNKPQGPP-PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPR 91
            A  P  P   G   P  PP P  G P  PP  G   P  PP PG    PPP    +  P 
Sbjct: 951  AAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1010

Query: 92   SPP----GKPQGPP-PQGGKPQGPPAQGGSKSQSARSP-PGKPQGPPQQEGNNPQGPPPP 145
             PP    G P  PP P  G P  PP  G         P  G P  PP      P  PP P
Sbjct: 1011 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1070

Query: 146  AGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 176
              G P  P  P AG P  PP P  G  P  P
Sbjct: 1071 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1101



 Score = 75.5 bits (184), Expect = 2e-14
 Identities = 55/148 (37%), Positives = 57/148 (38%), Gaps = 10/148 (6%)

Query: 39   PSPQGGNKPQGPPPPP----GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPP 94
            P P  G +   PPPPP    G P  PP  G      PP PG    PPP    +  P  PP
Sbjct: 899  PPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPP 958

Query: 95   ----GKPQGPP-PQGGKPQGPPAQGGSKSQSARSP-PGKPQGPPQQEGNNPQGPPPPAGG 148
                G P  PP P  G P  PP  G         P  G P  PP      P  PP P  G
Sbjct: 959  LPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1018

Query: 149  NPQQPQAPPAGQPQGPPRPPQGGRPSRP 176
             P  P  P AG P  PP P  G  P  P
Sbjct: 1019 IPPPPPLPGAGIPPPPPLPGAGIPPPPP 1046



 Score = 75.5 bits (184), Expect = 2e-14
 Identities = 56/149 (37%), Positives = 57/149 (38%), Gaps = 10/149 (6%)

Query: 36   PQGPSPQGGNKPQGPPPPPGK--PQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSP 93
            P  P P  G  P  PPP PG   P  PP  G   P  PP PG    PPP    +  P  P
Sbjct: 1021 PPPPLPGAGIPP--PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1078

Query: 94   P----GKPQGPP-PQGGKPQGPPAQG-GSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAG 147
            P    G P  PP P  G P  PP  G G          G P  PP      P  PP P  
Sbjct: 1079 PLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 1138

Query: 148  GNPQQPQAPPAGQPQGPPRPPQGGRPSRP 176
            G P  P  P  G P  PP P  G  P  P
Sbjct: 1139 GIPPPPPLPRVGIPPPPPLPGAGIPPPPP 1167



 Score = 75.1 bits (183), Expect = 3e-14
 Identities = 54/147 (36%), Positives = 55/147 (37%), Gaps = 6/147 (4%)

Query: 36   PQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPP- 94
            P  P P  G  P  P P  G    PP  G   P  PP PG    PPP    +  P  PP 
Sbjct: 911  PPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPL 970

Query: 95   ---GKPQGPP-PQGGKPQGPPAQGGSKSQSARSP-PGKPQGPPQQEGNNPQGPPPPAGGN 149
               G P  PP P  G P  PP  G         P  G P  PP      P  PP P  G 
Sbjct: 971  PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1030

Query: 150  PQQPQAPPAGQPQGPPRPPQGGRPSRP 176
            P  P  P AG P  PP P  G  P  P
Sbjct: 1031 PPPPPLPGAGIPPPPPLPGAGIPPPPP 1057



 Score = 75.1 bits (183), Expect = 3e-14
 Identities = 57/149 (38%), Positives = 58/149 (38%), Gaps = 10/149 (6%)

Query: 36   PQGPSPQGGNKPQGPPPPPGK--PQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSP 93
            P  P P  G  P  PPP PG   P  PP  G   P  PP PG    PPP    +  P  P
Sbjct: 1032 PPPPLPGAGIPP--PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1089

Query: 94   P----GKPQGPP-PQGGKPQGPPAQGGSKSQSARSP-PGKPQGPPQQEGNNPQGPPPPAG 147
            P    G P  PP P  G P  PP  G         P  G P  PP      P  PP P  
Sbjct: 1090 PLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRV 1149

Query: 148  GNPQQPQAPPAGQPQGPPRPPQGGRPSRP 176
            G P  P  P AG P  PP P  G  P  P
Sbjct: 1150 GIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1178



 Score = 73.9 bits (180), Expect = 7e-14
 Identities = 54/147 (36%), Positives = 55/147 (37%), Gaps = 6/147 (4%)

Query: 36   PQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPP- 94
            P  P P  G  P  P P  G P  PP  G   P  PP PG     PP    +  P  PP 
Sbjct: 922  PPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPL 981

Query: 95   ---GKPQGPP-PQGGKPQGPPAQGGSKSQSARSP-PGKPQGPPQQEGNNPQGPPPPAGGN 149
               G P  PP P  G P  PP  G         P  G P  PP      P  PP P  G 
Sbjct: 982  PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1041

Query: 150  PQQPQAPPAGQPQGPPRPPQGGRPSRP 176
            P  P  P AG P  PP P  G  P  P
Sbjct: 1042 PPPPPLPGAGIPPPPPLPGAGIPPPPP 1068



 Score = 70.5 bits (171), Expect = 7e-13
 Identities = 56/151 (37%), Positives = 57/151 (37%), Gaps = 21/151 (13%)

Query: 36   PQGPSPQGGNKPQGPPPPPGK--PQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSP 93
            P  P P  G  P  PPP PG   P  PP  G   P  PP PG    PPP   +   P  P
Sbjct: 1098 PPPPLPGVGIPP--PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPP 1155

Query: 94   P----GKPQGPP-PQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGG 148
            P    G P  PP P  G P  PP  G           G P  PP      P  PP P  G
Sbjct: 1156 PLPGAGIPPPPPLPGAGIPPPPPLPG----------VGIPPPPPLPGVGIPPPPPLPGAG 1205

Query: 149  NPQQPQAPPAGQP--QGPPRPPQGGRPSRPP 177
             P  P  P  G P    PP PP G     PP
Sbjct: 1206 IPPPPPLPGMGIPPAPAPPLPPPGTGIPPPP 1236



 Score = 70.1 bits (170), Expect = 1e-12
 Identities = 56/162 (34%), Positives = 57/162 (35%), Gaps = 21/162 (12%)

Query: 29   PSLIAGNPQGPSPQGGNKPQGPPPPPGK----------PQGPPPQGGNKPQGPPPPGKPQ 78
            P L         P  G  P  PPP PG           PQ PP QG      PPPP    
Sbjct: 859  PPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGA 918

Query: 79   GPPPQGDKSRSPRSPPGK---PQGPPPQGGKPQGPPAQGGSKSQSARSP-PGKPQGPPQQ 134
            G PP       P   PG    P  P P  G P  PP  G +       P  G P  PP  
Sbjct: 919  GIPP-------PPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLP 971

Query: 135  EGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 176
                P  PP P  G P  P  P AG P  PP P  G  P  P
Sbjct: 972  GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1013



 Score = 62.4 bits (150), Expect = 2e-10
 Identities = 50/144 (34%), Positives = 52/144 (36%), Gaps = 18/144 (12%)

Query: 45  NKPQGPPPPPGKPQGPPPQGGNKPQGPPP-PGK----------PQGPPPQGDKSRSPRSP 93
           N P  PP P  +     P  G  P  PPP PG           PQ PP QG +   P  P
Sbjct: 854 NIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPP 913

Query: 94  PGKPQGPPPQGGKPQGPPAQGGSKSQSARSP-PGKPQGPPQQEGNNPQGPPPPAGGNPQQ 152
           P       P  G P  PP  G         P  G P  PP      P  PP P  G P  
Sbjct: 914 P------LPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLP 967

Query: 153 PQAPPAGQPQGPPRPPQGGRPSRP 176
           P  P AG P  PP P  G  P  P
Sbjct: 968 PPLPGAGIPPPPPLPGAGIPPPPP 991



 Score = 62.0 bits (149), Expect = 3e-10
 Identities = 51/146 (34%), Positives = 53/146 (36%), Gaps = 26/146 (17%)

Query: 36   PQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPG 95
            P  P P  G  P  P P  G P  PP  G   P  PP PG    PPP       P    G
Sbjct: 1131 PPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPP-------PLPGVG 1183

Query: 96   KPQGPP-PQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGP----PPPAGGNP 150
             P  PP P  G P  PP  G           G P  PP      P  P    PPP  G P
Sbjct: 1184 IPPPPPLPGVGIPPPPPLPGA----------GIPPPPPLPGMGIPPAPAPPLPPPGTGIP 1233

Query: 151  QQPQAPPAGQPQGPPRPPQGGRPSRP 176
              P  P +    GPP  PQ G  + P
Sbjct: 1234 PPPLLPVS----GPPLLPQVGSSTLP 1255



 Score = 53.1 bits (126), Expect = 1e-07
 Identities = 50/146 (34%), Positives = 54/146 (36%), Gaps = 20/146 (13%)

Query: 36   PQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPG 95
            P  P P  G  P  P P  G P  PP  G   P  PP PG    PPP    +  P  PP 
Sbjct: 1153 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPL 1212

Query: 96   KPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKP-QGPP--QQEGNN----PQ-----GPP 143
               G PP    P  PP  G         PP  P  GPP   Q G++    PQ      PP
Sbjct: 1213 PGMGIPPAPAPPLPPPGTG------IPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPP 1266

Query: 144  PPAG--GNPQQPQAPPAGQPQGPPRP 167
             P+G  G           QP  P RP
Sbjct: 1267 LPSGLFGLGMNQDKGSRKQPIEPCRP 1292



 Score = 44.3 bits (103), Expect = 6e-05
 Identities = 48/176 (27%), Positives = 60/176 (34%), Gaps = 42/176 (23%)

Query: 42  QGGNKPQGPP----PPPGKPQGPP-----PQGGNKPQGPPPPGKPQGPPPQGDKSRSPRS 92
           QG  +P  PP    P PG   G       P GG   + P  P   Q      D   S  +
Sbjct: 227 QGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGG-AGEAPGSPDTEQALSALSDLPESLAA 285

Query: 93  PPGKPQGPPPQGGKPQG-----PPAQGGSK---------------SQSARSPPGKPQGPP 132
            P +PQ PP  GG P       P AQ  +K                + A   P +  G  
Sbjct: 286 EPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDT 345

Query: 133 QQEGNN------PQGPP-----PPAGGN-PQQPQAPPAGQPQGPPRPPQGGRPSRP 176
            +EG        P+G P     P  G + PQ+    P  + QGP  P     P  P
Sbjct: 346 DEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPAAASLPGSP 401



 Score = 42.4 bits (98), Expect = 2e-04
 Identities = 53/187 (28%), Positives = 58/187 (31%), Gaps = 60/187 (32%)

Query: 47  PQGPPPPPGKPQGP-------------------------PPQGGNKPQGPPPP------- 74
           P  PP PPG   GP                         P Q  ++P  PPPP       
Sbjct: 764 PGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQP--PPPPSLLWSAG 821

Query: 75  -GKPQGPPPQG-----------------DKSRSPRSPPGKP-----QGPPPQGGKPQGPP 111
            G+P   PP                     S +  SPP  P        P  G  P  PP
Sbjct: 822 QGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPP 881

Query: 112 AQGGSKSQSARSPPGKPQGPPQQ--EGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQ 169
              G    +  S    PQ PP Q  E   P  PP P  G P  P  P AG    PP P  
Sbjct: 882 PLPGMTVPTLPS-TAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGA 940

Query: 170 GGRPSRP 176
           G  P  P
Sbjct: 941 GIPPPPP 947



 Score = 35.4 bits (80), Expect = 0.026
 Identities = 33/101 (32%), Positives = 40/101 (39%), Gaps = 14/101 (13%)

Query: 33   AGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRS 92
            AG P  P   G   P  P PP      PPP  G     PPPP  P   PP   +  S   
Sbjct: 1204 AGIPPPPPLPGMGIPPAPAPPL-----PPPGTGI----PPPPLLPVSGPPLLPQVGSSTL 1254

Query: 93   PPGKPQG--PPPQGGKPQGPPAQGGSKSQSARSPPGKPQGP 131
            P  +  G  PPP    P G    G ++ + +R  P +P  P
Sbjct: 1255 PTPQVCGFLPPP---LPSGLFGLGMNQDKGSRKQPIEPCRP 1292



 Score = 32.7 bits (73), Expect = 0.17
 Identities = 40/169 (23%), Positives = 48/169 (28%), Gaps = 39/169 (23%)

Query: 48  QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP----------------------QGD 85
           Q  P   G     PP  G   + P PPG   GP                        Q  
Sbjct: 745 QTSPTEEGGVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPT 804

Query: 86  KSRSPRSPP---------GKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPP---- 132
           +S S   PP         G+P   PP     +   +   S S + ++    P  PP    
Sbjct: 805 QSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCT 864

Query: 133 ----QQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 177
                  G     PPPP       P  P    PQ PP       P  PP
Sbjct: 865 ESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPP 913


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 78.2 bits (191), Expect = 3e-15
 Identities = 58/178 (32%), Positives = 74/178 (41%), Gaps = 27/178 (15%)

Query: 28   SPSLIAGNPQGPSPQGGNKPQG--PPPPPGKPQGPPPQGGNKPQG---PPPPGKPQGPP- 81
            +P    G P  PSP+G   P    PP P G P  P P+G   P     P P G P   P 
Sbjct: 969  TPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPF 1028

Query: 82   PQGDKS---RSPRSPPGKPQGPPPQGGKPQGPPA-----QGGSKSQSARSPPGKPQG-PP 132
            P+G  +    +P SP G P   P   G P  P A     +GG  + S +  P  P   PP
Sbjct: 1029 PKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPP 1088

Query: 133  QQEGN----NPQGPPPPAGGNPQQPQA-----PPAGQPQGP---PRPPQGGRPSRPPQ 178
              +G     +P+G P P    P  P+      P  G P  P   P  P+GG  + PP+
Sbjct: 1089 SPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPK 1146



 Score = 71.2 bits (173), Expect = 4e-13
 Identities = 56/178 (31%), Positives = 66/178 (37%), Gaps = 35/178 (19%)

Query: 34   GNPQGPSPQGGNKPQG--PPPPPGKPQGPPPQGGNKPQGPPPP---GKPQGPPPQG---D 85
            G P  PSP+G   P    PP P G P  P P+    P    PP   G P  P P+G    
Sbjct: 929  GIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTP 988

Query: 86   KSRSPRSPPGKPQGPPPQG-------------GKPQGPPAQGGSKSQSARSPP---GKPQ 129
             + +P SP G P  P P+G             G P   P   G+ +  A +PP   G P 
Sbjct: 989  PAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPA 1048

Query: 130  GPPQQEG--NNPQGPPPPAGGNPQQPQ-----APPAGQPQ----GPPRPPQGGRPSRP 176
              P  +G    P    P   G P  P       PPA  P     GP  P   G P  P
Sbjct: 1049 ATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPP 1106



 Score = 70.9 bits (172), Expect = 6e-13
 Identities = 56/177 (31%), Positives = 73/177 (41%), Gaps = 27/177 (15%)

Query: 28   SPSLIAGNPQGPSPQGGNKPQG--PPPPPGKPQGPPPQGGNKPQGPPPPGKPQG---PPP 82
            +P    G P  PSP+G   P    PP P G    PP +G        PP    G   PPP
Sbjct: 1086 TPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPP 1145

Query: 83   QG---DKSRSPRSPPGKPQGPPPQGGKPQGPPA-----QGGSKSQSARSPPGKPQG-PPQ 133
            +G     + +P SP G    PPP+G  P  P A     +GG  + S +  P  P   PP 
Sbjct: 1146 KGAPTTPAATPPSPKGGLATPPPKGA-PTTPAATPPSPKGGLATPSPKGAPTTPAATPPS 1204

Query: 134  QEGN----NPQGPPPPAGGNPQQPQA-----PPAGQPQGP---PRPPQGGRPSRPPQ 178
             +G     +P+G P      P  P+       P G P  P   P  P+GG  + PP+
Sbjct: 1205 PKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPK 1261



 Score = 69.7 bits (169), Expect = 1e-12
 Identities = 53/162 (32%), Positives = 64/162 (39%), Gaps = 20/162 (12%)

Query: 24   SQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQ 83
            S + +P+  A  P  PSP+GG     P   P  P   PP        P P G P  P   
Sbjct: 1190 SPKGAPTTPAATP--PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTP--- 1244

Query: 84   GDKSRSPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSPP--GKPQ----GPPQQEGN 137
               + +P SP G P  PPP+G  P  P A   S      +PP  G P      PP  +G 
Sbjct: 1245 ---AATPPSPKGGPATPPPKGA-PTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGG 1300

Query: 138  NPQGPP-----PPAGGNPQQPQAPPAGQPQGPPRPPQGGRPS 174
                PP     PPA   P    +P    P+G P PP    PS
Sbjct: 1301 PATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPS 1342



 Score = 68.6 bits (166), Expect = 3e-12
 Identities = 55/169 (32%), Positives = 67/169 (39%), Gaps = 23/169 (13%)

Query: 28   SPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP------P 81
            +P+  A  P  PSP+GG     P   P  P   PP        P P G P  P      P
Sbjct: 1171 APTTPAATP--PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSP 1228

Query: 82   PQGDKSRSPRSPPGKPQGPPPQG-GKPQGPPAQGGSKSQSARSPPGKPQG---PPQQEGN 137
              G  + SP+  P  P   PP   G P  PP +G + +  A +PP    G   PP +   
Sbjct: 1229 KGGLATPSPKGAPTTPAATPPSPKGGPATPPPKG-APTPPAATPPSLKGGLATPPHKGAP 1287

Query: 138  NPQ--GPPPPAGG----NPQQPQAPPAGQPQGPP----RPPQGGRPSRP 176
            NP    PP P GG     P+    PPA  P  P      PP  G P+ P
Sbjct: 1288 NPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPP 1336



 Score = 67.8 bits (164), Expect = 5e-12
 Identities = 56/182 (30%), Positives = 70/182 (38%), Gaps = 35/182 (19%)

Query: 24   SQEESPSLIAGNPQGPSPQGGNKPQGPP--PPPGKPQGPPPQGGNKPQGPPPPGKPQGP- 80
            S + +P+  A  P  PSP+GG     P   P P     P P+GG  P  P P G P  P 
Sbjct: 935  SPKGAPTPPAATP--PSPKGGPATPSPKWAPTPPAATPPSPKGG--PATPSPKGAPTPPA 990

Query: 81   -----PPQGDKSRSPRSPPGKPQ-GPPPQGGKPQGPPAQGGSKSQSARSPP---GKPQGP 131
                 P  G  + SP+  P  P   PP   G P   P   G+ +  A +PP   G P   
Sbjct: 991  ATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAAT 1050

Query: 132  PQQEG---------NNPQG----------PPPPAGGNPQQPQAPPAGQPQGPPRPPQGGR 172
            P  +G          +P+G          P PPA   P     P    P+G P PP    
Sbjct: 1051 PLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATP 1110

Query: 173  PS 174
            PS
Sbjct: 1111 PS 1112



 Score = 67.8 bits (164), Expect = 5e-12
 Identities = 55/171 (32%), Positives = 65/171 (38%), Gaps = 31/171 (18%)

Query: 28   SPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGP---PPQGGNKPQGPPPPGKPQGP---P 81
            +P+  A  P  PSP+GG      PPP G P  P   PP        PPP G P  P   P
Sbjct: 1125 APTTPAATP--PSPKGG---LATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP 1179

Query: 82   PQGDKSRSPRSPPGKP-----QGPPPQGG----KPQGPPA---------QGGSKSQSARS 123
            P      +  SP G P       P P+GG     P+G P          +GG  + S + 
Sbjct: 1180 PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKG 1239

Query: 124  PPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPS 174
             P  P   P      P  PPP   G P  P A P     G   PP  G P+
Sbjct: 1240 APTTPAATPPSPKGGPATPPPK--GAPTPPAATPPSLKGGLATPPHKGAPN 1288



 Score = 67.0 bits (162), Expect = 8e-12
 Identities = 51/166 (30%), Positives = 64/166 (38%), Gaps = 18/166 (10%)

Query: 24   SQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP--- 80
            S + +P+  A  P  PSP+GG     P   P  P   PP     P  PPP G P  P   
Sbjct: 1213 SPKGAPTTPAATP--PSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAAT 1270

Query: 81   PP--QGDKSRSPRSPPGKP---QGPPPQGG----KPQGPPAQGGSKSQSARSPPGKPQGP 131
            PP  +G  +  P      P     P P+GG     P+G P    +   S +  PG P  P
Sbjct: 1271 PPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTP--P 1328

Query: 132  PQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 177
            P+     P   PP   G P  P   P+   +G P  P       PP
Sbjct: 1329 PKGAPTPPAVTPPSPKGTPTLPATTPSS--KGGPTTPSSKEGPTPP 1372



 Score = 66.6 bits (161), Expect = 1e-11
 Identities = 51/157 (32%), Positives = 64/157 (40%), Gaps = 22/157 (14%)

Query: 34   GNPQGPSPQGGNKPQG--PPPPPGKPQGPPPQGGNKPQGPPPPGKPQG---PPPQGDKSR 88
            G P  PS +G   P    PP P G P  P P+G   P    PP    G   PP +G    
Sbjct: 1069 GGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKG---- 1124

Query: 89   SPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQG----PPQQEGNNPQGPPP 144
            +P +P   P  P P+GG    PP   G+ +  A +PP    G    PP+     P   PP
Sbjct: 1125 APTTPAATP--PSPKGGLATPPPK--GAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP 1180

Query: 145  PAGGNPQQPQAPPAGQPQGP---PRPPQGGRPSRPPQ 178
               G    P   P G P  P   P  P+GG  +  P+
Sbjct: 1181 SPKGGLATPS--PKGAPTTPAATPPSPKGGLATPSPK 1215



 Score = 65.9 bits (159), Expect = 2e-11
 Identities = 54/179 (30%), Positives = 67/179 (37%), Gaps = 33/179 (18%)

Query: 24   SQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKP-----QGPPPQGG---NKPQGPPPPG 75
            S + +P+  A  P  PSP+GG      P P G P       P P+GG     P+G P P 
Sbjct: 958  SPKWAPTPPAATP--PSPKGG---PATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPP 1012

Query: 76   KPQGPPPQGD-------------KSRSPRSPPGKPQGPPPQGGKPQGPPA-----QGGSK 117
                P P+G               + +P SP G P   P   G P  P A     +GG  
Sbjct: 1013 AVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPA 1072

Query: 118  SQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 176
            + S +  P  P   P      P  P P   G P  P A P     G   PP  G P+ P
Sbjct: 1073 TPSLKGAPTPPAATPPSPKGGPATPSPK--GAPMPPAATPPSPKGGLATPPHKGAPTTP 1129



 Score = 65.1 bits (157), Expect = 3e-11
 Identities = 50/170 (29%), Positives = 63/170 (37%), Gaps = 32/170 (18%)

Query: 28   SPSLIAGNPQGPSPQGGNKPQGPPPP----------------PGKPQGPPPQGGNKPQGP 71
            +P    G P  P P+G   P    PP                P     P P+GG  P   
Sbjct: 1247 TPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGG--PATS 1304

Query: 72   PPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGKPQ---GPPAQGGSKSQSARSPPGK- 127
            PP G P  P      + +P SP G P  PPP+G        PP+  G+ +  A +P  K 
Sbjct: 1305 PPKGAPTPP------AATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKG 1358

Query: 128  -PQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 176
             P  P  +EG  P    P   G P      P    +GP  P   G P+ P
Sbjct: 1359 GPTTPSSKEGPTPPAATPSHKGGPAM---TPPSPKRGPAIPSPKGDPTSP 1405



 Score = 64.3 bits (155), Expect = 5e-11
 Identities = 46/149 (30%), Positives = 59/149 (39%), Gaps = 22/149 (14%)

Query: 46   KPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDK------SRSPRSPPGKPQG 99
            K +  P P G P  P P+G   P    PP    GP     K      + +P SP G P  
Sbjct: 920  KARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPAT 979

Query: 100  PPPQGGKPQGPPA------QGGSKSQSARSPPGKPQ-GPPQQEGNN-----PQGPPPPAG 147
            P P+G     PPA      +GG  + S +  P  P   PP  +G+      P+G   P  
Sbjct: 980  PSPKGAPT--PPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPA 1037

Query: 148  GNPQQPQAPPAGQ--PQGPPRPPQGGRPS 174
              P  P+  PA    P+G P  P    PS
Sbjct: 1038 ATPPSPKGSPAATPLPKGAPTTPAATLPS 1066



 Score = 62.4 bits (150), Expect = 2e-10
 Identities = 49/146 (33%), Positives = 57/146 (39%), Gaps = 20/146 (13%)

Query: 39   PSPQGGNKP---QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPG 95
            PSP+GG      +G P PP     P P+GG  P  P P G P  P      + +P SP G
Sbjct: 1065 PSPKGGPATPSLKGAPTPPAATP-PSPKGG--PATPSPKGAPMPP------AATPPSPKG 1115

Query: 96   KPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGP-----PPPAGGNP 150
                 PP  G P  P A   S      +PP  P+G P      P  P      PP  G P
Sbjct: 1116 -GLATPPHKGAPTTPAATPPSPKGGLATPP--PKGAPTTPAATPPSPKGGLATPPPKGAP 1172

Query: 151  QQPQAPPAGQPQGPPRPPQGGRPSRP 176
              P A P     G   P   G P+ P
Sbjct: 1173 TTPAATPPSPKGGLATPSPKGAPTTP 1198



 Score = 61.6 bits (148), Expect = 3e-10
 Identities = 51/167 (30%), Positives = 66/167 (39%), Gaps = 30/167 (17%)

Query: 35   NPQGPSPQGGNKPQGPPP--PPG----KPQGPPPQGGNKP---QGPPPPGKPQGPP---- 81
            +P  PSP+G   P    P  P G      + P P   N P   +GP  P   Q P     
Sbjct: 855  SPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMT 914

Query: 82   -PQGDKSRSPRSPPGKPQGPPPQGG---------KPQGPPAQGGSK---SQSARSPPGKP 128
                 K+R+  +P G P  P P+G           P+G PA    K   +  A +PP   
Sbjct: 915  SSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPK 974

Query: 129  QGPPQQEGNNPQGPPPPAGGNPQQPQAPPA-GQPQGPPRPPQGGRPS 174
             GP      +P+G P P    P  P+  PA   P+G P PP    PS
Sbjct: 975  GGPATP---SPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPS 1018



 Score = 57.8 bits (138), Expect = 5e-09
 Identities = 48/159 (30%), Positives = 64/159 (40%), Gaps = 25/159 (15%)

Query: 39   PSPQGGNKP---QGPPPPPGKPQGPPPQGGNKPQG----PPPPGKPQGPPPQG---DKSR 88
            P+P   N P   +GP  P  K         + P+     P P G P  P P+G     + 
Sbjct: 886  PTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAA 945

Query: 89   SPRSPPGKPQGPPPQGGKPQGPPA------QGGSKSQSARSPPGKPQG-PPQQEGN---- 137
            +P SP G P  P P+      PPA      +GG  + S +  P  P   PP  +G     
Sbjct: 946  TPPSPKGGPATPSPKWAPT--PPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATP 1003

Query: 138  NPQGPPPPAGGNPQQPQAPPAGQ--PQGPPRPPQGGRPS 174
            +P+G P P    P  P+  PA    P+G   PP    PS
Sbjct: 1004 SPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPS 1042



 Score = 53.5 bits (127), Expect = 9e-08
 Identities = 45/159 (28%), Positives = 63/159 (39%), Gaps = 16/159 (10%)

Query: 28   SPSLIAGNPQGPSPQGGNKPQG--PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP--- 82
            +P    G+P  P P+G   P    PP P G P  P     +K  GP  P   +GP P   
Sbjct: 1316 TPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSK-GGPTTPSSKEGPTPPAA 1374

Query: 83   ----QGDKSRSPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNN 138
                +G  + +P SP   P  P P+ G P  P     S  ++  +P  +       +G+ 
Sbjct: 1375 TPSHKGGPAMTPPSPKRGPAIPSPK-GDPTSPAVIPLSPKKAPATPVTREGAATPSKGD- 1432

Query: 139  PQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQG-GRPSRP 176
                 PPA       +AP    P+G P  P   G P+ P
Sbjct: 1433 ---LTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLP 1468



 Score = 53.1 bits (126), Expect = 1e-07
 Identities = 47/166 (28%), Positives = 63/166 (37%), Gaps = 29/166 (17%)

Query: 39   PSPQGG---NKPQGPPPPPGK-------PQG-PPPQGGNKPQG---PPPPGKPQGPPPQG 84
            PSP+GG   + P+G P PP           G PPP+G   P     P P G P  P    
Sbjct: 1295 PSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTP 1354

Query: 85   DKSRSPRSPPGKPQGPPPQGGKP--QGPPAQ---GGSKSQSARSPPGKPQGP------PQ 133
                 P +P  K +GP P    P  +G PA       +  +  SP G P  P      P+
Sbjct: 1355 SSKGGPTTPSSK-EGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPK 1413

Query: 134  QEGNNP---QGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 176
            +    P   +G   P+ G+   P   P    + P      G P+ P
Sbjct: 1414 KAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATP 1459



 Score = 48.1 bits (113), Expect = 4e-06
 Identities = 46/159 (28%), Positives = 65/159 (40%), Gaps = 16/159 (10%)

Query: 24   SQEESPSLIAGNPQGPS-PQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP 82
            S + +P+L A  P     P   +  +GP PP   P     +GG     P P   P  P P
Sbjct: 1342 SPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSH---KGGPAMTPPSPKRGPAIPSP 1398

Query: 83   QGDKSRS---PRSPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNP 139
            +GD +     P SP   P  P  + G     P++ G  +  A +P    + P     + P
Sbjct: 1399 KGDPTSPAVIPLSPKKAPATPVTREG--AATPSK-GDLTPPAVTPVSLKKAPAT---SAP 1452

Query: 140  QGPP--PPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 176
            +G P  P + G+P  P   P   P+ PP P Q    S P
Sbjct: 1453 KGGPATPSSKGDPTLPAVTPP-SPKEPPAPKQVATSSSP 1490



 Score = 44.7 bits (104), Expect = 4e-05
 Identities = 48/201 (23%), Positives = 69/201 (34%), Gaps = 46/201 (22%)

Query: 23   VSQEESPSLIA--GNPQGPSPQGG-NKPQGPPPPPGKPQGPPPQGGNK-----PQGPPPP 74
            VS +++P+  A  G P  PS +G    P   PP P +P  P     +      P  P P 
Sbjct: 1441 VSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPM 1500

Query: 75   GKPQGP------PPQGDKSRSPRSPPGKPQGP-----------PPQGGKPQGPPAQGGSK 117
            G P  P      P +   + S R  P  P              P +   P         K
Sbjct: 1501 GAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKK 1560

Query: 118  SQSARSPPGKPQGPPQQEGNNPQG-----------------PPPPAGGNPQQPQAPPAGQ 160
            + +  +P   P  P  +E ++P                   PP     +P++   PPA  
Sbjct: 1561 TPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVT 1620

Query: 161  P----QGPPRPPQGGRPSRPP 177
            P    +GP  P   G P+ PP
Sbjct: 1621 PPSPEKGPATPAPKGTPTSPP 1641



 Score = 41.6 bits (96), Expect = 4e-04
 Identities = 43/165 (26%), Positives = 59/165 (35%), Gaps = 17/165 (10%)

Query: 24   SQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPG----KPQG 79
            S +E+P+  A  P  PSP+ G      P P G P  PP    +    P  P     K   
Sbjct: 1609 SPKEAPTPPAVTP--PSPEKG---PATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGA 1663

Query: 80   PPPQGDKSRSPRSPPGKPQ----GPPPQGGKPQGPPAQGG--SKSQSARSPPGKPQGPPQ 133
              PQ  K    +  P   +     P P+       P + G  +K  SA SPP  P    +
Sbjct: 1664 TVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAK 1723

Query: 134  QEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ 178
                 P     PA   P Q  +    + +     P+G  P  PP+
Sbjct: 1724 NGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKG--PLAPPE 1766



 Score = 40.8 bits (94), Expect = 6e-04
 Identities = 42/161 (26%), Positives = 56/161 (34%), Gaps = 21/161 (13%)

Query: 18  NLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP 77
           NL+  VS  E+  L         P+     QG    P     P P     P+G P P   
Sbjct: 823 NLSSPVSPVEASFL---------PENSLSFQGSKDSPATTHSPTPPS---PKGAPTPSAV 870

Query: 78  QGPPPQGDKSRSPRSP-PGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEG 136
               P+G       +P P     P P+ G     P Q  + S ++ SP  K +  P  +G
Sbjct: 871 TPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPK-KARATPAPKG 929

Query: 137 NNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 177
                   PA  +P+    PPA  P  P   P    P   P
Sbjct: 930 I-------PASPSPKGAPTPPAATPPSPKGGPATPSPKWAP 963



 Score = 37.7 bits (86), Expect = 0.005
 Identities = 45/183 (24%), Positives = 63/183 (34%), Gaps = 15/183 (8%)

Query: 7    SVALLALSSAQNLNEDVSQEESPSLIAGN--PQGPSPQGGNKPQGPPPPPGKPQGPPPQG 64
            S A++ LS  +     V++E + +   G+  P   +P    K      P G P  P  +G
Sbjct: 1404 SPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKG 1463

Query: 65   GNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQ----- 119
                    PP   + P P+   + S  SP   P  P P G  P  P     S  +     
Sbjct: 1464 DPTLPAVTPPSPKEPPAPKQVATSS--SPKKAPATPAPMGA-PTLPAVIPSSPKEVPATP 1520

Query: 120  SARSPPGKPQGPPQQEGNNPQGPP-----PPAGGNPQQPQAPPAGQPQGPPRPPQGGRPS 174
            S+R  P  P      +       P     PPA   P   + P    P+  P  P     S
Sbjct: 1521 SSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEAS 1580

Query: 175  RPP 177
             PP
Sbjct: 1581 SPP 1583



 Score = 35.8 bits (81), Expect = 0.020
 Identities = 46/168 (27%), Positives = 53/168 (31%), Gaps = 37/168 (22%)

Query: 36   PQGPSPQGGNKPQGP----PPPPGKP-------QGPPPQGGNKPQGP--PPPGKPQGP-- 80
            P  P P   N  +GP     P P  P               + P+GP  PP  K   P  
Sbjct: 1715 PICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLT 1774

Query: 81   ----------PPQGDKSRSPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQSAR--SPPGKP 128
                      P     S +P  P   P  P P    P  PP Q    S        P KP
Sbjct: 1775 AAAFEKVLPKPESASVSAAPSPPVSLPLAPSPV---PTLPPKQQFLPSSPGLVLESPSKP 1831

Query: 129  QGPPQQEGNNPQGPPPP-AGGNPQQ------PQAPPAGQPQGPPRPPQ 169
              P  ++   P  PP P +GG P Q      P    AG P   P   Q
Sbjct: 1832 LAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQ 1879



 Score = 34.7 bits (78), Expect = 0.044
 Identities = 26/108 (24%), Positives = 35/108 (32%), Gaps = 8/108 (7%)

Query: 39   PSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQ 98
            PSP+   K    P P   P  P  +  + P    P      P P+        + P   +
Sbjct: 1556 PSPK---KTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKE 1612

Query: 99   GPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPA 146
             P P    P  P      K  +  +P G P  PP    +    P  PA
Sbjct: 1613 APTPPAVTPPSP-----EKGPATPAPKGTPTSPPVTPSSLKDSPTSPA 1655



 Score = 31.2 bits (69), Expect = 0.49
 Identities = 34/146 (23%), Positives = 50/146 (34%), Gaps = 10/146 (6%)

Query: 39   PSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQ 98
            P+P+  + P    P    PQ       + P  P P  K     P    + +P  P  K  
Sbjct: 1688 PAPE--STPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDS 1745

Query: 99   GPPPQGG----KPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQ 154
                +G      P+GP A   SK+ +  +     +  P+ E  +    P P    P  P 
Sbjct: 1746 SKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPS 1805

Query: 155  APPAGQPQGPPRPPQGG----RPSRP 176
              P   P+    P   G     PS+P
Sbjct: 1806 PVPTLPPKQQFLPSSPGLVLESPSKP 1831



 Score = 30.4 bits (67), Expect = 0.84
 Identities = 49/190 (25%), Positives = 60/190 (31%), Gaps = 25/190 (13%)

Query: 7   SVALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGP--PPQG 64
           +V  L  ++ +N     S   SP +    P  P      K  G P P GKP      P G
Sbjct: 558 TVLPLVQAAPKNSPSFQSTSSSPEI----PLSPEATLAKKSLGEPLPIGKPASSMTSPLG 613

Query: 65  GNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGP----PPQGGKPQGPPAQGGSKSQS 120
            N            GP   G   +S    P     P     P G  P    A+G S   +
Sbjct: 614 VNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPT--TAKGTSTYTT 671

Query: 121 ARSP------PGKPQGPPQQEGNNPQGPPPPAGG-------NPQQPQAPPAGQPQGPPRP 167
             SP         P+  P +EG     P  P          +PQ   AP A     P  P
Sbjct: 672 TASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIP 731

Query: 168 PQGGRPSRPP 177
                PS PP
Sbjct: 732 KSVPSPSLPP 741


>gi|11386183 WAS protein family, member 2 [Homo sapiens]
          Length = 498

 Score = 77.8 bits (190), Expect = 5e-15
 Identities = 54/149 (36%), Positives = 60/149 (40%), Gaps = 21/149 (14%)

Query: 29  PSLIAGNPQGPSPQGGNKPQGPPPPP---GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGD 85
           P+   G+P GP P     P  PPPPP   G P  PPP G   P  PPPP  P   PP  D
Sbjct: 302 PAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPS-PPSFPPHPD 360

Query: 86  KSRSPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPP 145
            +  P      P  PPP    P  PP      +  A  PP  P  PP      P  PPPP
Sbjct: 361 FAAPP------PPPPPPAADYPTLPPPPLSQPTGGA--PPPPPPPPP------PGPPPPP 406

Query: 146 AGGNPQQPQAPPAGQPQGPPRPPQGGRPS 174
             G   QP  PP   P      P+   P+
Sbjct: 407 FTGADGQPAIPP---PLSDTTKPKSSLPA 432



 Score = 76.6 bits (187), Expect = 1e-14
 Identities = 55/148 (37%), Positives = 58/148 (39%), Gaps = 25/148 (16%)

Query: 38  GPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKP 97
           GP       P  PPP P  P G PP  G KP   PPP  P  PPP            G P
Sbjct: 288 GPKRSSVVSPSHPPPAP--PLGSPP--GPKPGFAPPPAPPPPPPPM----------IGIP 333

Query: 98  QGPPPQG-GKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPP----AGGNPQQ 152
             PPP G G P  PP                P  PP    + P  PPPP     GG P  
Sbjct: 334 PPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPP 393

Query: 153 PQAPPAGQPQGPPRPP---QGGRPSRPP 177
           P  PP   P GPP PP     G+P+ PP
Sbjct: 394 PPPPP---PPGPPPPPFTGADGQPAIPP 418



 Score = 62.8 bits (151), Expect = 2e-10
 Identities = 49/157 (31%), Positives = 58/157 (36%), Gaps = 21/157 (13%)

Query: 29  PSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK-------PQGPP 81
           P+L+  N      +  +    PPPP       P    ++   PPPP +        +G  
Sbjct: 226 PTLVYQNGSIGCVENVDASSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSG 285

Query: 82  PQGDKSRSPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQG 141
             G K  S  SP   P  PP   G P GP             PP  P  PP   G  P  
Sbjct: 286 LAGPKRSSVVSPSHPPPAPPL--GSPPGP-------KPGFAPPPAPPPPPPPMIGIPP-- 334

Query: 142 PPPPAG-GNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 177
           PPPP G G+P  P  PP   P  PP P     P  PP
Sbjct: 335 PPPPVGFGSPGTP--PPPSPPSFPPHPDFAAPPPPPP 369


>gi|119829187 alpha 1 type XVII collagen [Homo sapiens]
          Length = 1497

 Score = 77.8 bits (190), Expect = 5e-15
 Identities = 66/188 (35%), Positives = 78/188 (41%), Gaps = 55/188 (29%)

Query: 33  AGNPQGPSPQGGNKPQGPPPPPGKP-----------------------QGPP-PQGGNKP 68
           +G+P  P   G   PQG P  PG+P                        GPP P G   P
Sbjct: 772 SGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGP 831

Query: 69  QGPP-------PPGKP--------QGPP----PQGDKSRSPRSPPGKPQGPPPQG-GKPQ 108
            GPP       P G P        QGPP    P+G    S   PPG P+GPP +G   P 
Sbjct: 832 PGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPG-PRGPPGEGLPGPP 890

Query: 109 GPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQ--PQAPPAGQP----- 161
           GPP    S S++  S P  P GPP  +G+  QGPP P G   +Q  P    +G       
Sbjct: 891 GPPGSFLSNSETFLSGPPGPPGPPGPKGD--QGPPGPRGHQGEQGLPGFSTSGSSSFGLN 948

Query: 162 -QGPPRPP 168
            QGPP PP
Sbjct: 949 LQGPPGPP 956



 Score = 75.9 bits (185), Expect = 2e-14
 Identities = 72/205 (35%), Positives = 82/205 (40%), Gaps = 59/205 (28%)

Query: 23   VSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKP----QGPPPPGKPQ 78
            V+ E S  L    P  P P G   P GPP  PG P GP    G++     QGPP P  P+
Sbjct: 809  VTSEGSSMLTVPGP--PGPPGAMGPPGPPGAPG-PAGPAGLPGHQEVLNLQGPPGPPGPR 865

Query: 79   GPPPQGDKSRSPRSPPGKPQGPPPQG-GKPQGPPAQGGSKSQSARS----PPGKP----- 128
            GPP       S   PPG P+GPP +G   P GPP    S S++  S    PPG P     
Sbjct: 866  GPP-----GPSIPGPPG-PRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGD 919

Query: 129  QGPPQQEGN-------------------NPQGPPPPAG-----GNPQQPQAPPA-GQPQG 163
            QGPP   G+                   N QGPP P G     G+   P  P A G P G
Sbjct: 920  QGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSG 979

Query: 164  PPR-----------PPQGGRPSRPP 177
            P             PP    P  PP
Sbjct: 980  PSEGGSSSTMYVSGPPGPPGPPGPP 1004



 Score = 68.9 bits (167), Expect = 2e-12
 Identities = 60/153 (39%), Positives = 66/153 (43%), Gaps = 26/153 (16%)

Query: 37  QGPSPQGG--NKP--QGPPPPPGKPQGPPPQGGNKPQG-PPPPGKP--QGPPPQGDK--- 86
           QGP  + G    P  +GPP P G P  P   G   PQG P  PG+P  +G P    K   
Sbjct: 751 QGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVT 810

Query: 87  --SRSPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQG-PPQQEGNNPQGPP 143
               S  + PG P GPP   G P GPP   G         P  P G P  QE  N QGPP
Sbjct: 811 SEGSSMLTVPGPP-GPPGAMGPP-GPPGAPG---------PAGPAGLPGHQEVLNLQGPP 859

Query: 144 PPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 176
            P G  P+ P  P    P GP  PP  G P  P
Sbjct: 860 GPPG--PRGPPGPSIPGPPGPRGPPGEGLPGPP 890



 Score = 67.0 bits (162), Expect = 8e-12
 Identities = 65/203 (32%), Positives = 72/203 (35%), Gaps = 80/203 (39%)

Query: 35   NPQGP-SPQGGNKPQGP--PPPPGKPQGPPPQGGNKPQGPP-------------PPGKPQ 78
            N QGP  P G   P GP  P PPG P+GPP +G   P GPP             PPG P 
Sbjct: 854  NLQGPPGPPGPRGPPGPSIPGPPG-PRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPG 912

Query: 79   GPPPQGDKS----------------------------RSPRSPPGKPQGP---------P 101
             P P+GD+                             + P  PPG PQGP         P
Sbjct: 913  PPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPG-PQGPKGDKGDPGVP 971

Query: 102  PQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQ--------- 152
               G P GP   G S +     PPG P GPP      P G    +G   QQ         
Sbjct: 972  GALGIPSGPSEGGSSSTMYVSGPPG-PPGPP-----GPPGSISSSGQEIQQYISEYMQSD 1025

Query: 153  --------PQAPPAGQPQGPPRP 167
                     Q PP   P GPP P
Sbjct: 1026 SIRSYLSGVQGPPG--PPGPPGP 1046



 Score = 63.5 bits (153), Expect = 9e-11
 Identities = 51/154 (33%), Positives = 58/154 (37%), Gaps = 19/154 (12%)

Query: 34  GNPQGPSPQGGNKPQGPPPPPGKPQGPP---PQGGNKPQGPPPPGKPQGPPPQGDKSR-- 88
           G P  P P G   PQGP    G    P    P G    +GP  P    GPP  G+K    
Sbjct: 588 GTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGREGPMGPRGEAGPPGSGEKGERG 647

Query: 89  -----SPRSPPGKPQGPPPQGGK----PQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNP 139
                 P  PPG P    P+G      PQGPP   G   Q  R   G P G    +G  P
Sbjct: 648 AAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVG--LQGLRGEVGLP-GVKGDKG--P 702

Query: 140 QGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRP 173
            GPP P G   ++      G+P     P   G P
Sbjct: 703 MGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEP 736



 Score = 57.8 bits (138), Expect = 5e-09
 Identities = 61/191 (31%), Positives = 71/191 (37%), Gaps = 62/191 (32%)

Query: 47  PQGPPPPPGKPQGPPPQGGNKPQGPPPP------------------GKPQGPP-PQGDKS 87
           P GPP  PG        G   PQGPP P                    P GPP P+GD+ 
Sbjct: 654 PHGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQG 713

Query: 88  -RSPRSPPGKP--QGPPPQGGKP--------------QGPPA-QGGSKSQSARSPPGKPQ 129
            + PR   G+P  +G P   G+P              QGP   QG +     R PPG P 
Sbjct: 714 EKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPG-PS 772

Query: 130 GPPQQEG-NNPQGPP--PPAGGNP---QQPQAP----------------PAGQP--QGPP 165
           G P + G   PQGP   P   G P    +P AP                P G P   GPP
Sbjct: 773 GDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPP 832

Query: 166 RPPQGGRPSRP 176
            PP    P+ P
Sbjct: 833 GPPGAPGPAGP 843



 Score = 43.1 bits (100), Expect = 1e-04
 Identities = 37/120 (30%), Positives = 42/120 (35%), Gaps = 28/120 (23%)

Query: 32   IAGNPQGPSPQGGNKPQGPPPPPGK---PQGPPPQGGNKP---QGPPPPGKPQGPPPQGD 85
            + G P  P PQG    +G P  PG    P GP   G +      GPP P  P GPP    
Sbjct: 949  LQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPP---- 1004

Query: 86   KSRSPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPP 145
                         G     G+          +S S RS     QGPP      P GPP P
Sbjct: 1005 -------------GSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPP-----GPPGPPGP 1046



 Score = 42.4 bits (98), Expect = 2e-04
 Identities = 31/79 (39%), Positives = 33/79 (41%), Gaps = 23/79 (29%)

Query: 48   QGPPPPPGKPQGPPP-------------------QGGNKPQGPPPPGKPQGPP-PQGDKS 87
            QGPP  PG PQGPP                    Q     QGPP      G P P+GD  
Sbjct: 1398 QGPPGQPG-PQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGD-- 1454

Query: 88   RSPRSPPGKPQGPPPQGGK 106
            R P  PPG P  P P+G K
Sbjct: 1455 RGPAGPPGHPGPPGPRGHK 1473



 Score = 40.8 bits (94), Expect = 6e-04
 Identities = 37/81 (45%), Positives = 39/81 (48%), Gaps = 20/81 (24%)

Query: 98   QGPPPQGGKPQGPPAQGGSKSQSARSPP-----------GKPQGPPQQEGNNPQGPPPPA 146
            QGPP Q G PQGPP  G SK  SA S             G  QGPP Q+G    G P P 
Sbjct: 1398 QGPPGQPG-PQGPP--GISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGE--MGTPGPK 1452

Query: 147  GGNPQQPQAPPAGQPQGPPRP 167
            G   + P  PP G P GPP P
Sbjct: 1453 G--DRGPAGPP-GHP-GPPGP 1469



 Score = 37.4 bits (85), Expect = 0.007
 Identities = 48/176 (27%), Positives = 58/176 (32%), Gaps = 63/176 (35%)

Query: 9    ALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQG--------------GNKPQGPPPPP 54
            +LL+L  A+  +  +S   S  +  G P  P P G              G++ +G   PP
Sbjct: 1121 SLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPP 1180

Query: 55   GKPQGPPPQGGNK-----------------------PQGPPPPGKPQGPP---------- 81
            G P GPP   GN                        P GPP P  P+GPP          
Sbjct: 1181 GPP-GPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYA 1239

Query: 82   -PQGDKSRSP----------RSPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPG 126
                D  RS           RS    P GPP     PQGPP      S  A    G
Sbjct: 1240 AENSDSFRSELISYLTSPDVRSFIVGPPGPP----GPQGPPGDSRLLSTDASHSRG 1291



 Score = 34.3 bits (77), Expect = 0.058
 Identities = 25/79 (31%), Positives = 27/79 (34%), Gaps = 5/79 (6%)

Query: 69   QGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKP 128
            QGPP    PQGPP       +  +            G  QGPP Q G            P
Sbjct: 1398 QGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGP 1457

Query: 129  QGPPQQEGNNPQGPPPPAG 147
             GPP        GPP P G
Sbjct: 1458 AGPP-----GHPGPPGPRG 1471



 Score = 29.6 bits (65), Expect = 1.4
 Identities = 14/29 (48%), Positives = 15/29 (51%), Gaps = 1/29 (3%)

Query: 39   PSPQGGNKPQGPPPPPGKPQGPPPQGGNK 67
            P P+G   P GPP  PG P GP    G K
Sbjct: 1449 PGPKGDRGPAGPPGHPG-PPGPRGHKGEK 1476


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score = 77.4 bits (189), Expect = 6e-15
 Identities = 62/192 (32%), Positives = 75/192 (39%), Gaps = 46/192 (23%)

Query: 28   SPSLIAGNPQGPSPQGGNKPQGPPPPPGK--------PQGPPPQGGNKPQGPPPPGKPQG 79
            +P  + G  +GP   G     GP  PPG         P+GPP   G   +G       +G
Sbjct: 1351 APGQVIGG-EGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERG 1409

Query: 80   PPPQGDKSRSPRSP--PGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPG----------- 126
            PP  G+   +P  P  PG P  P PQG  P GPP + G K  S    PG           
Sbjct: 1410 PPGPGEGGIAPGEPGLPGLPGSPGPQG--PVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQ 1467

Query: 127  KPQGPPQQEG----------------NNPQGPPPPAG--GNPQQPQAPPAGQPQGPPRPP 168
             P+GPP   G                   +GPP PAG  G P     P A  P+GPP P 
Sbjct: 1468 GPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPT 1527

Query: 169  ----QGGRPSRP 176
                + G P RP
Sbjct: 1528 GRQGEKGEPGRP 1539



 Score = 63.5 bits (153), Expect = 9e-11
 Identities = 54/154 (35%), Positives = 65/154 (42%), Gaps = 25/154 (16%)

Query: 42   QGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPG--KPQGPP--------PQGDKSRSPR 91
            +G     GPP  PG P  P P G       P PG    QGPP        P  +  + P+
Sbjct: 2069 RGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPK 2128

Query: 92   SPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAG--GN 149
               G P G     G+P GP  Q G+           P+G P  +G  P+GPP P G  G+
Sbjct: 2129 GDRGVP-GIKGDRGEP-GPRGQDGNPGLPGERGMAGPEGKPGLQG--PRGPPGPVGGHGD 2184

Query: 150  PQQPQAP----PAGQPQGPP----RPPQGGRPSR 175
            P  P AP    PAG PQGP      P + G P R
Sbjct: 2185 PGPPGAPGLAGPAG-PQGPSGLKGEPGETGPPGR 2217



 Score = 61.6 bits (148), Expect = 3e-10
 Identities = 65/210 (30%), Positives = 73/210 (34%), Gaps = 68/210 (32%)

Query: 34   GNPQGPSPQGGNKPQGPPPPPG--------KPQGPP--------------------PQGG 65
            G    P   G     GPP  PG         PQGPP                    P   
Sbjct: 1254 GQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRA 1313

Query: 66   NKPQGPPPP---GKPQGPPPQGDK-SRSPRSPPGKPQGPPPQ--GGKPQGPPAQGGSKSQ 119
              P  P  P   G P  P P+GD   R PR P G+P G P Q  GG+  G P + G    
Sbjct: 1314 GNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEP-GAPGQVIGGEGPGLPGRKGDPGP 1372

Query: 120  SARSPPGK--------PQGPPQQEG---------NNPQGPPPP-----AGGNPQQPQAPP 157
            S   PPG         P+GPP   G            +GPP P     A G P  P  P 
Sbjct: 1373 S--GPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPG 1430

Query: 158  AGQPQGPPRPP---------QGGRPSRPPQ 178
            +  PQGP  PP         + G P  P Q
Sbjct: 1431 SPGPQGPVGPPGKKGEKGDSEDGAPGLPGQ 1460



 Score = 61.6 bits (148), Expect = 3e-10
 Identities = 53/188 (28%), Positives = 66/188 (35%), Gaps = 54/188 (28%)

Query: 27   ESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDK 86
            E P L  G    P P G   P+GP   PG P+GPP   G   +G       +GPP  G+ 
Sbjct: 1359 EGPGL-PGRKGDPGPSGPPGPRGPLGDPG-PRGPPGLPGTAMKGDKGDRGERGPPGPGEG 1416

Query: 87   SRSPRSP--PGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKP---------------- 128
              +P  P  PG P  P PQG  P GPP + G K  S    PG P                
Sbjct: 1417 GIAPGEPGLPGLPGSPGPQG--PVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPG 1474

Query: 129  ----------------------QGPPQQEGNN----------PQGPPPPAGGNPQQPQAP 156
                                  +GPP   G+            +GP  P G   +Q +  
Sbjct: 1475 AIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKG 1534

Query: 157  PAGQPQGP 164
              G+P  P
Sbjct: 1535 EPGRPGDP 1542



 Score = 60.8 bits (146), Expect = 6e-10
 Identities = 51/160 (31%), Positives = 56/160 (35%), Gaps = 35/160 (21%)

Query: 26   EESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPP-PQGGNKPQGPP------PPGKPQ 78
            E  P    GNP  P  +G   P+G P   G P+GPP P GG+   GPP       P  PQ
Sbjct: 2142 EPGPRGQDGNPGLPGERGMAGPEGKPGLQG-PRGPPGPVGGHGDPGPPGAPGLAGPAGPQ 2200

Query: 79   GPP----------PQGDKSRSPRSPPGKPQGPPPQG-----------------GKPQGPP 111
            GP           P G     P    G P  P P G                 GKP  P 
Sbjct: 2201 GPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPG 2260

Query: 112  AQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQ 151
              G S     R  PG P  P       P+G P P G   Q
Sbjct: 2261 RDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQ 2300



 Score = 60.5 bits (145), Expect = 8e-10
 Identities = 56/175 (32%), Positives = 67/175 (38%), Gaps = 37/175 (21%)

Query: 36   PQGPSPQGGNKP-QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSP- 93
            P+G   + G    +G   PPG P  P   G   PQGPP     +G          P SP 
Sbjct: 1252 PKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPG 1311

Query: 94   ----PGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGN------------ 137
                PG P G P   G P  P  +G    +  R P G+P  P Q  G             
Sbjct: 1312 RAGNPGTP-GAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDP 1370

Query: 138  NPQGPPPPAG--GNPQQPQAPPAGQP-------------QGPPRPPQGG-RPSRP 176
             P GPP P G  G+P  P+ PP G P             +GPP P +GG  P  P
Sbjct: 1371 GPSGPPGPRGPLGDP-GPRGPP-GLPGTAMKGDKGDRGERGPPGPGEGGIAPGEP 1423



 Score = 59.7 bits (143), Expect = 1e-09
 Identities = 49/165 (29%), Positives = 69/165 (41%), Gaps = 36/165 (21%)

Query: 34   GNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSP 93
            G+P    P+G     GPP PPG+     P  G + +G P     +GP       R P+  
Sbjct: 1685 GSPGSSGPKGDRGEPGPPGPPGRLVDTGP--GAREKGEPGDRGQEGP-------RGPKGD 1735

Query: 94   PGKPQGPPPQGGKP-QGPPAQGGSKSQSARSPPGK--PQGPPQQEGNN----------PQ 140
            PG P  P  +G +  +GPP   G      R P G+   +GPP  +G +          P 
Sbjct: 1736 PGLPGAPGERGIEGFRGPPGPQG--DPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPS 1793

Query: 141  GPPPPAG--GNPQQPQAP----------PAGQPQGPPRPPQGGRP 173
            GP   AG  G+P +   P          P+G P  P +P + G+P
Sbjct: 1794 GPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKP 1838



 Score = 58.9 bits (141), Expect = 2e-09
 Identities = 53/175 (30%), Positives = 69/175 (39%), Gaps = 25/175 (14%)

Query: 24   SQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQG--GNK-PQGPPPPGKPQGP 80
            S++ +P L  G P  P  QG   P G   P G    P P G  G K  +GPP P   +G 
Sbjct: 1450 SEDGAPGL-PGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGL 1508

Query: 81   PPQGDK--SRSPRSPPGKP--QGPPPQGGKPQGP----PAQGGSKSQSARSPPGKPQGPP 132
            P    +  ++ P  PPG    QG   + G+P  P    PA  G K +     P  P+G  
Sbjct: 1509 PGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGAT 1568

Query: 133  QQEGNNPQGPPPPAGGNPQQPQAPP-----------AGQPQGPPRPPQGGRPSRP 176
              +G   +GPP         P+  P           AG P     P + G P RP
Sbjct: 1569 GVQGE--RGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRP 1621



 Score = 57.8 bits (138), Expect = 5e-09
 Identities = 48/164 (29%), Positives = 65/164 (39%), Gaps = 34/164 (20%)

Query: 38   GPSPQGGNKPQGPPPPPGKPQGPPPQGGNK----PQGPP----------PPGKPQGPP-- 81
            GP  + G K +  PP P   +G P   G      P+GPP           PG+P  P   
Sbjct: 1486 GPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVV 1545

Query: 82   ------PQGDKSR-SPRSPPGK-----PQGPP----PQGGKPQGPPAQGGSKSQSARSPP 125
                  P+G+K    P  P G       +GPP    P    P+G P   G    + R+ P
Sbjct: 1546 GPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGP 1605

Query: 126  GKPQGPPQQEGN-NPQGPPPPAGGNPQQPQAPPAGQPQGPPRPP 168
                GPP ++G+    GPP P G   +  +    G  +GPP  P
Sbjct: 1606 PGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGD-EGPPGDP 1648



 Score = 56.6 bits (135), Expect = 1e-08
 Identities = 48/163 (29%), Positives = 63/163 (38%), Gaps = 24/163 (14%)

Query: 36   PQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPG 95
            P  P P+G    +GP    G+  GPP   G  P     PG+P  P P G + R       
Sbjct: 1582 PGDPGPKGDPGDRGPIGLTGRA-GPPGDSG-PPGEKGDPGRPGPPGPVGPRGRDGEVGEK 1639

Query: 96   KPQGPPPQGGKPQGPPAQGGSKSQSARSPPGK--PQGPPQQEGNN-------------PQ 140
              +GPP   G P     +G   +   R P G+   QG P ++G N               
Sbjct: 1640 GDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEP 1699

Query: 141  GPPPPAG-----GNPQQPQAPPAGQPQGPPRPPQG--GRPSRP 176
            GPP P G     G   + +  P  + Q  PR P+G  G P  P
Sbjct: 1700 GPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAP 1742



 Score = 56.2 bits (134), Expect = 1e-08
 Identities = 56/182 (30%), Positives = 68/182 (37%), Gaps = 29/182 (15%)

Query: 22   DVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP 81
            D   +  P L  G    P P G     G P  PG P  P   GG    G P     +G  
Sbjct: 2010 DPGPQGPPGLALGERGPPGPSG---LAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEK 2066

Query: 82   PQ-GDKSRS-PRSPPGKPQGPPPQGGK------------PQGPPAQGGSKSQSARSPPGK 127
             + G++ R  P   PG P  P P G K             QGPP   G+K +   +    
Sbjct: 2067 GERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQG 2126

Query: 128  PQGPPQQEG-NNPQGPPPPAG--GNPQQP----QAPPAGQ-----PQGPPRPPQGGRPSR 175
            P+G     G    +G P P G  GNP  P     A P G+     P+GPP P  G     
Sbjct: 2127 PKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPG 2186

Query: 176  PP 177
            PP
Sbjct: 2187 PP 2188



 Score = 55.8 bits (133), Expect = 2e-08
 Identities = 47/141 (33%), Positives = 58/141 (41%), Gaps = 14/141 (9%)

Query: 39   PSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP-PQGDKSRSPRSPPGKP 97
            P  +G     GP    G P  P  +G   P+G P    P+GPP P G        PPG P
Sbjct: 2134 PGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVG--GHGDPGPPGAP 2191

Query: 98   QGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAG-----GNPQQ 152
                P G  PQGP    G   ++   PPG+    P      P GPP P+G     G+P  
Sbjct: 2192 GLAGPAG--PQGPSGLKGEPGET--GPPGRGLTGPTGAVGLP-GPPGPSGLVGPQGSPGL 2246

Query: 153  P-QAPPAGQPQGPPRPPQGGR 172
            P Q    G+P  P R    G+
Sbjct: 2247 PGQVGETGKPGAPGRDGASGK 2267



 Score = 54.7 bits (130), Expect = 4e-08
 Identities = 54/184 (29%), Positives = 71/184 (38%), Gaps = 34/184 (18%)

Query: 26   EESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPP----PPGKPQGPP 81
            +  P  + G    P   G    +G P  PG P    P+G +   G      PPG P  P 
Sbjct: 1593 DRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPG 1652

Query: 82   PQGDK----SRSPRSPPGK--PQGPPPQGGKPQGPPAQGGSKSQSARSPPGKP-----QG 130
              G++    +   R P G+   QG P + G+   P + G    +    PPG P      G
Sbjct: 1653 KAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTG 1712

Query: 131  PPQQEGNNP-----QGPPPPAGGNPQQPQAP----------PAGQPQGPP--RPPQGGRP 173
            P  +E   P     +GP  P  G+P  P AP          P G PQG P  R P G + 
Sbjct: 1713 PGAREKGEPGDRGQEGPRGPK-GDPGLPGAPGERGIEGFRGPPG-PQGDPGVRGPAGEKG 1770

Query: 174  SRPP 177
             R P
Sbjct: 1771 DRGP 1774



 Score = 54.3 bits (129), Expect = 5e-08
 Identities = 49/174 (28%), Positives = 67/174 (38%), Gaps = 10/174 (5%)

Query: 5    LLSVALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQG 64
            LL  A +  S+ + + E    E S S +    +   P+G +  QGPP   G    P  +G
Sbjct: 1945 LLETAGIKASALREIVE-TWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERG 2003

Query: 65   GNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGKP--QGPPAQGGSKSQSAR 122
                +G P    PQGPP     +   R PPG P G   + GKP   G P + G   ++ R
Sbjct: 2004 LKGDRGDP---GPQGPP---GLALGERGPPG-PSGLAGEPGKPGIPGLPGRAGGVGEAGR 2056

Query: 123  SPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 176
                  +G   + G   +  PP   G P  P  P        P P   G    P
Sbjct: 2057 PGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPP 2110



 Score = 53.1 bits (126), Expect = 1e-07
 Identities = 41/133 (30%), Positives = 50/133 (37%), Gaps = 18/133 (13%)

Query: 39   PSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPP-PPGKPQGPPPQGDKSRSPRSPPGK- 96
            P  +G   P+GP   PG P  P  +G    +GPP P G P    P G+K    R PPG  
Sbjct: 1721 PGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKG--DRGPPGLD 1778

Query: 97   -------------PQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPP 143
                         P GP    GK   P   G    +  +  PG P GPP   G   +   
Sbjct: 1779 GRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPG-PSGPPGLPGKPGEDGK 1837

Query: 144  PPAGGNPQQPQAP 156
            P   G   +P  P
Sbjct: 1838 PGLNGKNGEPGDP 1850



 Score = 52.4 bits (124), Expect = 2e-07
 Identities = 45/149 (30%), Positives = 62/149 (41%), Gaps = 21/149 (14%)

Query: 36   PQGPSPQGGNK-PQGPPPPPGKP--------QGPP----PQGGNKPQGPPPP----GKPQ 78
            P+G   + G K  +GPP  PG P        +G P    P G    QG P      G P 
Sbjct: 1629 PRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPG 1688

Query: 79   GPPPQGDKSR-SPRSPPGKPQGPPPQGGKPQGPPAQGGSKS-QSARSPPGKPQGPPQQEG 136
               P+GD+    P  PPG+     P G + +G P   G +  +  +  PG P  P ++  
Sbjct: 1689 SSGPKGDRGEPGPPGPPGRLVDTGP-GAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGI 1747

Query: 137  NNPQGPPPPAGGNPQQPQAPPAGQPQGPP 165
               +GPP P G    +  A   G  +GPP
Sbjct: 1748 EGFRGPPGPQGDPGVRGPAGEKGD-RGPP 1775



 Score = 50.8 bits (120), Expect = 6e-07
 Identities = 41/136 (30%), Positives = 53/136 (38%), Gaps = 8/136 (5%)

Query: 33   AGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKS-RSPR 91
            AG P  P   G     G P  PG+   P  +G   P+G    G    P P+GD+  +  R
Sbjct: 2646 AGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDR--GFDGQPGPKGDQGEKGER 2703

Query: 92   SPPGKPQGPPPQGGK----PQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAG 147
              PG    P P G      P GPP   G +           +GPP +      G P   G
Sbjct: 2704 GTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPG 2763

Query: 148  GNPQQPQAPPAGQPQG 163
               +Q +  PAG P+G
Sbjct: 2764 ERGEQGRPGPAG-PRG 2778



 Score = 48.5 bits (114), Expect = 3e-06
 Identities = 52/177 (29%), Positives = 67/177 (37%), Gaps = 47/177 (26%)

Query: 32   IAGNPQGPSPQGGNKPQGPPPPPGKPQ----GPPPQGGNK--PQG--------PPPPGKP 77
            + G+P  P P G   P+G P P G P     G P   G K  P G        P   G  
Sbjct: 2276 VPGSPGLPGPVG---PKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDR 2332

Query: 78   QGPPPQGDKSRSPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGK--PQGPPQQE 135
              P P+G+K  + R+  G+P  P   G K  G P   G K       PG   P GPP  +
Sbjct: 2333 GLPGPRGEKGEAGRA--GEPGDPGEDGQK--GAPGPKGFKGDPGVGVPGSPGPPGPPGVK 2388

Query: 136  GN-------------------NPQGPPPPAGGNPQQPQAPPAGQ-----PQGPPRPP 168
            G+                    P+G     G + ++  A P G+     P GPP PP
Sbjct: 2389 GDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPP 2445



 Score = 47.8 bits (112), Expect = 5e-06
 Identities = 45/162 (27%), Positives = 58/162 (35%), Gaps = 33/162 (20%)

Query: 38   GPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDK---SRSPRSPP 94
            GP+  G    +G   P G       QG   P G   PG P      GD+     + R+ P
Sbjct: 1546 GPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGP 1605

Query: 95   GKPQGPPPQGGKP--QGPPAQGGSKSQSA-------RSPPGKP----------------- 128
                GPP + G P   GPP   G + +           PPG P                 
Sbjct: 1606 PGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGV 1665

Query: 129  QGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQ--PQGPPRPP 168
            +GP  ++G+  QG P   G N     + P G     GPP PP
Sbjct: 1666 RGPVGEKGD--QGDPGEDGRNGSPGSSGPKGDRGEPGPPGPP 1705



 Score = 47.4 bits (111), Expect = 7e-06
 Identities = 49/178 (27%), Positives = 59/178 (33%), Gaps = 49/178 (27%)

Query: 34   GNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPP-------PGKPQGPPPQGDK 86
            G P  P  +G    +GPP P G P    P G    +GPP         GKP    P G  
Sbjct: 1737 GLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPN 1796

Query: 87   SRS----------------------PRSPPGKPQGPPPQGGKP--------QGPPAQGGS 116
              +                      P  PPG P G P + GKP         G P + G 
Sbjct: 1797 GAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLP-GKPGEDGKPGLNGKNGEPGDPGEDGR 1855

Query: 117  KSQSARSPPGKPQGPPQQEGNN-------PQGP---PPPAGGNPQQ-PQAPPAGQPQG 163
            K +   S     +G    +G         PQGP   P P G   Q  P  P    P+G
Sbjct: 1856 KGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKG 1913



 Score = 47.0 bits (110), Expect = 9e-06
 Identities = 47/167 (28%), Positives = 63/167 (37%), Gaps = 23/167 (13%)

Query: 32   IAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG-DKSRSP 90
            + G P     +G   P+G     G+   P   G +  +G P P   +G P  G   S  P
Sbjct: 2322 LVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGP 2381

Query: 91   RSPPG--KPQGPPPQGGKP--QGPPAQGGSKSQSARSPPGKPQ---GPPQQEG-NNPQGP 142
              PPG     G P   G P   G P Q G + +  +  P   +   GPP +EG   P GP
Sbjct: 2382 PGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGP 2441

Query: 143  PPPAG--------------GNPQQPQAPPAGQPQGPPRPPQGGRPSR 175
            P P G              G+P      P G+   P    + GRP +
Sbjct: 2442 PGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQ 2488



 Score = 46.2 bits (108), Expect = 1e-05
 Identities = 44/141 (31%), Positives = 57/141 (40%), Gaps = 15/141 (10%)

Query: 34   GNPQGPSPQGGNKPQGPPPPPGKPQGPP------PQGGNKPQGPPPPGKPQGPPPQGDKS 87
            G P  P   G +   G    PG P  P       P+G   P G P       P  +G+K 
Sbjct: 2254 GKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKG 2313

Query: 88   RSPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAG 147
             +P    G   G P   G  +G P   G K ++ R+  G+P G P ++G   +G P P G
Sbjct: 2314 -APGGLAGDLVGEPGAKG-DRGLPGPRGEKGEAGRA--GEP-GDPGEDGQ--KGAPGPKG 2366

Query: 148  GNPQQPQAPPAGQPQGPPRPP 168
                 P     G P GPP PP
Sbjct: 2367 FK-GDPGVGVPGSP-GPPGPP 2385



 Score = 45.8 bits (107), Expect = 2e-05
 Identities = 56/185 (30%), Positives = 70/185 (37%), Gaps = 47/185 (25%)

Query: 34   GNPQGPSPQGGNKPQGPPPPPG--KPQGPPPQGGNKPQGPPP---PGKPQGPPPQGDKSR 88
            G+      +G + P+G    PG   PQGPP   G  P GPP    PG P G  P+GD+  
Sbjct: 1860 GDSGASGREGRDGPKGERGAPGILGPQGPPGLPG--PVGPPGQGFPGVPGGTGPKGDRGE 1917

Query: 89   SPRSPPGKPQGPPPQGGKPQGPP------AQGGSKS---------------------QSA 121
            +         G     G+P   P         G K+                     +  
Sbjct: 1918 TGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERR 1977

Query: 122  RSPPGK--PQGPPQQEGNNPQGPPPPAG-----GNPQQPQAPP--AGQPQGPPRPP-QGG 171
            R P G    QGPP +EG  P G P   G     G+P  PQ PP  A   +GPP P    G
Sbjct: 1978 RGPKGDSGEQGPPGKEG--PIGFPGERGLKGDRGDP-GPQGPPGLALGERGPPGPSGLAG 2034

Query: 172  RPSRP 176
             P +P
Sbjct: 2035 EPGKP 2039



 Score = 45.8 bits (107), Expect = 2e-05
 Identities = 38/124 (30%), Positives = 50/124 (40%), Gaps = 6/124 (4%)

Query: 32   IAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPR 91
            + G    P  +G   P+G     G+P     QG    +G P  G   G P   D S  P 
Sbjct: 2666 VPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPG-PSGNDGSAGPP 2724

Query: 92   SPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQ 151
             PPG      P+G   QG   + G   +     PG P G P + G   QG P PAG   +
Sbjct: 2725 GPPGSVGPRGPEG--LQGQKGERGPPGERVVGAPGVP-GAPGERGE--QGRPGPAGPRGE 2779

Query: 152  QPQA 155
            + +A
Sbjct: 2780 KGEA 2783



 Score = 43.9 bits (102), Expect = 7e-05
 Identities = 44/139 (31%), Positives = 54/139 (38%), Gaps = 15/139 (10%)

Query: 26   EESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNK-PQGPPPPGKPQGPPPQG 84
            +  PS   G    P  +G   P GPP PPG   GPP   G K  +G P  G P GP    
Sbjct: 2417 QPGPSGERGLAGPPGREGIPGPLGPPGPPGS-VGPPGASGLKGDKGDPGVGLP-GP---- 2470

Query: 85   DKSRSPRSPPG--KPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNP--Q 140
               R  R  PG     G P Q G P+G     GS+ +          G    +G++    
Sbjct: 2471 ---RGERGEPGIRGEDGRPGQEG-PRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVIL 2526

Query: 141  GPPPPAGGNPQQPQAPPAG 159
            GPP P G      +  P G
Sbjct: 2527 GPPGPRGAKGDMGERGPRG 2545



 Score = 41.2 bits (95), Expect = 5e-04
 Identities = 39/129 (30%), Positives = 46/129 (35%), Gaps = 15/129 (11%)

Query: 33   AGNPQGPSPQGGNKPQGPPPP------PGKPQGPPPQGGNKPQGPP-PPGKPQGPPPQGD 85
            AG+P      G    QG P P      PGKP      G N   G P  PG+      +GD
Sbjct: 1802 AGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGD 1861

Query: 86   KSRSPRSPPGKPQGPPPQGG--KPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPP 143
               S R     P+G     G   PQGPP   G      +  PG P       G  P+G  
Sbjct: 1862 SGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVP------GGTGPKGDR 1915

Query: 144  PPAGGNPQQ 152
               G   +Q
Sbjct: 1916 GETGSKGEQ 1924



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 46/157 (29%), Positives = 60/157 (38%), Gaps = 31/157 (19%)

Query: 41   PQGGNKPQGPPPPPGKP--QGPPPQGGNK-------PQGPPPPGKPQGP----PPQGDKS 87
            PQG     G P  PG P   G P   G K       P+G       +G       +GDK 
Sbjct: 2585 PQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKG 2644

Query: 88   RSPRSPPGKP--QGPPPQGGKPQGPPAQGGSKSQSARSPP-------GKPQGPPQQEGNN 138
             +   PPG+P   G   + G+P G P Q G+  +     P       G+P GP   +G  
Sbjct: 2645 EA--GPPGRPGLAGHKGEMGEP-GVPGQSGAPGKEGLIGPKGDRGFDGQP-GPKGDQGEK 2700

Query: 139  PQGPPPPAGGNPQQPQAPPAGQPQGP-----PRPPQG 170
             +   P  GG P       +  P GP     PR P+G
Sbjct: 2701 GERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEG 2737



 Score = 31.6 bits (70), Expect = 0.38
 Identities = 27/80 (33%), Positives = 37/80 (46%), Gaps = 13/80 (16%)

Query: 29   PSLIAGNPQGPSPQGGNKPQGPPPPPGK--PQGPPPQGGNKPQGPPPPGKPQGPPPQGDK 86
            PS   G+   P P G   P+GP    G+   +GPP   G +  G   PG P  P  +G++
Sbjct: 2714 PSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPP---GERVVG--APGVPGAPGERGEQ 2768

Query: 87   SRSPRSPPGKPQGPPPQGGK 106
             R     PG P GP  + G+
Sbjct: 2769 GR-----PG-PAGPRGEKGE 2782


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 76.3 bits (186), Expect = 1e-14
 Identities = 58/148 (39%), Positives = 67/148 (45%), Gaps = 23/148 (15%)

Query: 41  PQGGNKPQGPPPPPGKP--QGPPPQGGNKPQGPPPPGKPQGPPPQG------------DK 86
           P+G   P+GP  P G P   G P Q G    GPP P  P GPP  G            +K
Sbjct: 113 PKGDTGPRGPRGPAGPPGRDGIPGQPGLP--GPPGPPGPPGPPGLGGNFAPQLSYGYDEK 170

Query: 87  SRSPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPA 146
           S    S PG P GP    G P GPP  G    Q  + PPG+P  P       P+GPP P 
Sbjct: 171 STGGISVPG-PMGPSGPRGLP-GPP--GAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPP 226

Query: 147 GGNPQQPQAPPAGQP--QGPPRPPQGGR 172
           G N    +A   G+P  +GPP  PQG R
Sbjct: 227 GKNGDDGEAGKPGRPGERGPP-GPQGAR 253



 Score = 75.1 bits (183), Expect = 3e-14
 Identities = 56/165 (33%), Positives = 71/165 (43%), Gaps = 21/165 (12%)

Query: 32  IAGNPQGPSPQGGNKPQGPPPPPG------KPQGPPPQGGNKPQGPPPPGKPQGPP-PQG 84
           IAG P  P  +G + PQGP  PPG      +P  P  +G    +G P P   QGPP P G
Sbjct: 405 IAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAG 464

Query: 85  DKS-RSPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSP-----------PGKPQGPP 132
           ++  R  R  PG P G P   G+  GP ++G   +     P           P  P+G P
Sbjct: 465 EEGKRGARGEPG-PTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSP 523

Query: 133 QQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPP-QGGRPSRP 176
            + G   +   P A G    P +P      GPP P  Q GRP  P
Sbjct: 524 GEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPP 568



 Score = 75.1 bits (183), Expect = 3e-14
 Identities = 62/178 (34%), Positives = 71/178 (39%), Gaps = 37/178 (20%)

Query: 33   AGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP-PQGDK-SRSP 90
            AG    P P G   P GPP P GK  G  P+G   P G P    P GPP P G+K S   
Sbjct: 880  AGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGA 939

Query: 91   RSPPGKPQGPPPQG-----------------------GKPQGPPAQGGSKSQSARSPPGK 127
              P G P  P PQG                       G    P  QG S +   R PPG 
Sbjct: 940  DGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPG- 998

Query: 128  PQGPP---QQEGNNPQGPPPPAGGNPQQPQAPPA----GQ--PQGPPRPPQGGRPSRP 176
            P GPP      G + +   P A G+P +  +P A    G+  P GPP  P  G P  P
Sbjct: 999  PMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAP--GAPGAP 1054



 Score = 73.9 bits (180), Expect = 7e-14
 Identities = 59/171 (34%), Positives = 68/171 (39%), Gaps = 36/171 (21%)

Query: 34   GNPQGPSPQGGNKPQGPPPPPGKPQGPPPQG-----GNKPQ-GPPPPGKPQGPP------ 81
            G+P     +G   P GPP  PG P  P P G     G++ + GP  P  P GP       
Sbjct: 1028 GSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPA 1087

Query: 82   ----PQGDKSRS----PRSPPGKP-----QGPPPQGGKPQGPPAQGGSKSQSARSPPGKP 128
                P+GDK  +     R   G       QGPP   G P      G S     R PPG  
Sbjct: 1088 GPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGS- 1146

Query: 129  QGPPQQEGNN----PQGPPPPAG----GNPQQPQAPPAGQPQGPPRPPQGG 171
             G P ++G N    P GPP P G      P  P  PP   P GPP PP  G
Sbjct: 1147 AGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPG--PPGPPGPPSAG 1195



 Score = 70.5 bits (171), Expect = 7e-13
 Identities = 53/158 (33%), Positives = 62/158 (39%), Gaps = 25/158 (15%)

Query: 36  PQGPSPQGGNK----PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPR 91
           P GP+   G+K    P GP  P G    P  +G   P GP     P G   Q      P 
Sbjct: 771 PPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPG 830

Query: 92  SPPGKPQGPPPQGGKPQGPP-------AQGGSKSQSARSPPGKP--------QGPPQQEG 136
               K    PP    P GPP       A G   ++ +  PPG           GPP   G
Sbjct: 831 DAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSG 890

Query: 137 N-NPQGPPPPA---GGNPQQPQAPPAGQP--QGPPRPP 168
           N  P GPP PA   GG   + +  PAG+P   GPP PP
Sbjct: 891 NAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPP 928



 Score = 70.1 bits (170), Expect = 1e-12
 Identities = 54/158 (34%), Positives = 59/158 (37%), Gaps = 28/158 (17%)

Query: 34  GNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP--------PQGD 85
           G P  P P G   P G    PG    P   G     GPP P  P GPP        P   
Sbjct: 803 GEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAK 862

Query: 86  KSRSPRSPPGK-----------PQGPPPQGGKPQGPPAQGGSKSQSARSPPGK--PQGPP 132
            +R    PPG            P GP    G P GPP   G   +  + P G+  P G P
Sbjct: 863 GARGSAGPPGATGFPGAAGRVGPPGPSGNAG-PPGPPGPAG--KEGGKGPRGETGPAGRP 919

Query: 133 QQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQG 170
            + G  P GPP PAG         PAG P  P   PQG
Sbjct: 920 GEVG--PPGPPGPAGEKGSPGADGPAGAPGTP--GPQG 953



 Score = 68.9 bits (167), Expect = 2e-12
 Identities = 52/172 (30%), Positives = 62/172 (36%), Gaps = 25/172 (14%)

Query: 27  ESPSLIAGNPQGPSPQGGNKPQGPPPPPGKP-----QGPP-------------PQGGNKP 68
           E P  + G P  P P G   P G P   G+P      G P             P G   P
Sbjct: 364 EGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGP 423

Query: 69  QGPPPP----GKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSP 124
            GPP P    G+P  P  +GD        P   QGPP   G+     A+G         P
Sbjct: 424 GGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGP 483

Query: 125 PGKPQGPPQQ---EGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRP 173
           PG+  GP  +     +   GP  PAG       A P G P    RP + G P
Sbjct: 484 PGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLP 535



 Score = 68.2 bits (165), Expect = 4e-12
 Identities = 61/189 (32%), Positives = 70/189 (37%), Gaps = 46/189 (24%)

Query: 29  PSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPP----------PPGKP- 77
           P  + G P  P PQG    QGPP  PG+P    P G   P GPP           PG+P 
Sbjct: 186 PRGLPGPPGAPGPQGF---QGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPG 242

Query: 78  -QGPP-PQG----------------------DKSRSPRSPPGKPQGPPPQGGKPQGPPAQ 113
            +GPP PQG                      D ++    P G P+G P   G+   P   
Sbjct: 243 ERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAG-PKGEPGSPGENGAPGQM 301

Query: 114 GGSKSQSARSPPGKPQGPPQQEGNN----PQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQ 169
           G       R  PG P GP    GN+      GPP P G  P  P   P          PQ
Sbjct: 302 GPRGLPGERGRPGAP-GPAGARGNDGATGAAGPPGPTG--PAGPPGFPGAVGAKGEAGPQ 358

Query: 170 GGRPSRPPQ 178
           G R S  PQ
Sbjct: 359 GPRGSEGPQ 367



 Score = 66.6 bits (161), Expect = 1e-11
 Identities = 63/194 (32%), Positives = 78/194 (40%), Gaps = 44/194 (22%)

Query: 26  EESPSLIAGNPQGPSPQGGNKPQGP---PPPPGKPQGPPPQG--GNK----PQGPPPPGK 76
           +  P+   G P  P   G     GP   P   G+P  P P G  GN       GPP P  
Sbjct: 279 DAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTG 338

Query: 77  PQGPP-------------PQGDK-SRSPRSPPGKPQGPPPQG--GKPQGPPAQGGSKSQS 120
           P GPP             PQG + S  P+   G+P  P P G  G    P A G   ++ 
Sbjct: 339 PAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKG 398

Query: 121 ARSPP---GKPQGPPQQEGNNPQGP--PPPAGGNPQQPQAPPA-------GQP-----QG 163
           A   P   G P  P  +  + PQGP  PP   GN  +P AP +       G+P     QG
Sbjct: 399 ANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQG 458

Query: 164 PPRP--PQGGRPSR 175
           PP P   +G R +R
Sbjct: 459 PPGPAGEEGKRGAR 472



 Score = 66.2 bits (160), Expect = 1e-11
 Identities = 64/211 (30%), Positives = 86/211 (40%), Gaps = 65/211 (30%)

Query: 26  EESPSLIAGNPQGPSPQGGNK-------PQGPPPPPGKPQGPP------------PQGGN 66
           E  P  + G P GP+ + G +       P G P PPG+  GP             P+G  
Sbjct: 450 EPGPVGVQG-PPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPA 508

Query: 67  KPQGPPPPGKPQGPPPQGDK------------SRSPRS--PPGK--PQGPPPQGGKPQGP 110
             +G P P  P+G P +  +            + SP S  P GK  P GP  Q G+P GP
Sbjct: 509 GERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRP-GP 567

Query: 111 PAQGGSKSQSA-------------------RSPPGKP--QGPPQQEGN-NPQGPPPPAGG 148
           P   G++ Q+                    R  PG P   GP  ++G    QGPP PAG 
Sbjct: 568 PGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGP 627

Query: 149 NPQQPQAPPAGQP-----QGPPRPP-QGGRP 173
             ++ +  PAG P      GP  PP + G+P
Sbjct: 628 AGERGEQGPAGSPGFQGLPGPAGPPGEAGKP 658



 Score = 65.5 bits (158), Expect = 2e-11
 Identities = 67/219 (30%), Positives = 80/219 (36%), Gaps = 60/219 (27%)

Query: 16  AQNLNEDVSQEESPSLIAGNPQGPS-------PQGGNKPQGPPPPPGKPQGPPPQGGNKP 68
           A  L+    ++ +  +    P GPS       P G   PQG   PPG+P  P   G   P
Sbjct: 160 APQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGP 219

Query: 69  QGPP-PPGK--------------PQGPP-PQG----------------------DKSRSP 90
           +GPP PPGK               +GPP PQG                      D ++  
Sbjct: 220 RGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGD 279

Query: 91  RSPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNN-------PQGPP 143
             P G P+G P   G+   P   G       R  PG P GP    GN+       P GP 
Sbjct: 280 AGPAG-PKGEPGSPGENGAPGQMGPRGLPGERGRPGAP-GPAGARGNDGATGAAGPPGPT 337

Query: 144 PPAG--GNPQQPQAPPAGQPQGP--PRPPQG--GRPSRP 176
            PAG  G P    A     PQGP     PQG  G P  P
Sbjct: 338 GPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPP 376



 Score = 63.5 bits (153), Expect = 9e-11
 Identities = 54/173 (31%), Positives = 71/173 (41%), Gaps = 30/173 (17%)

Query: 33  AGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNK----------PQG-PPPPGKPQGPP 81
           +G P  P  +G    +G P P G  QGPP   G +          P G P PPG+  GP 
Sbjct: 433 SGEPGAPGSKGDTGAKGEPGPVGV-QGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPG 491

Query: 82  PQG----DKSRSPRSPPGK--------PQGPPPQGGKPQG---PPAQGGSKSQSARSPPG 126
            +G    D    P+ P G+        P+G P + G+P     P A+G + S  +  P G
Sbjct: 492 SRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDG 551

Query: 127 K--PQGPPQQEGN-NPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 176
           K  P GP  Q+G   P GPP   G         P G    P +  + G P  P
Sbjct: 552 KTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPP 604



 Score = 63.5 bits (153), Expect = 9e-11
 Identities = 61/204 (29%), Positives = 72/204 (35%), Gaps = 58/204 (28%)

Query: 29   PSLIAGNPQGPSP---QGGNKPQGPPPPPGKP-----QGPPPQGGNK-------PQGPPP 73
            PS  AG P  P P   +GG  P+G   P G+P      GPP   G K       P G P 
Sbjct: 888  PSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPG 947

Query: 74   PGKPQG----------------------PPPQGDKSRS-------PRSPPGKPQGPPPQG 104
               PQG                      P P G+  +         R PPG P GPP   
Sbjct: 948  TPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPG-PMGPPGLA 1006

Query: 105  GKP-----------QGPPAQGGSKSQSARSPPGKPQGPPQQEG-NNPQGPPPPAGGNPQQ 152
            G P           +G P + GS           P GPP   G     GP  PAG +  +
Sbjct: 1007 GPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDR 1066

Query: 153  PQAPPAGQPQGPPRPPQGGRPSRP 176
             +  PAG P GP  P     P+ P
Sbjct: 1067 GETGPAG-PAGPVGPVGARGPAGP 1089



 Score = 60.1 bits (144), Expect = 1e-09
 Identities = 59/185 (31%), Positives = 69/185 (37%), Gaps = 51/185 (27%)

Query: 32  IAGNPQGPSPQGGNKPQGP------PPPPGKPQG---------PPPQGGNKPQG------ 70
           + G+P  P P G   P GP      P PPG P           P P+G     G      
Sbjct: 540 LTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERG 599

Query: 71  -PPPPGK-----------PQGPP----PQGDKS-RSPRSPPG-----KPQGPPPQGGKP- 107
            P PPG             QGPP    P G++  + P   PG      P GPP + GKP 
Sbjct: 600 VPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPG 659

Query: 108 -QGPP----AQGGSKSQSARSPPGK--PQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQ 160
            QG P    A G S ++  R  PG+   QGPP   G       P   G      AP A  
Sbjct: 660 EQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPG 719

Query: 161 PQGPP 165
            QG P
Sbjct: 720 SQGAP 724



 Score = 59.3 bits (142), Expect = 2e-09
 Identities = 55/184 (29%), Positives = 66/184 (35%), Gaps = 47/184 (25%)

Query: 41  PQGGNKPQGPPPPPGK--------PQGPP----PQGGNKPQGPPPPGKPQGP-------- 80
           P G   P GPP  PG         PQGP     PQG     GPP P    GP        
Sbjct: 333 PPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADG 392

Query: 81  ---------------PPQGDKSRSPRSP--PGKPQGPPPQGGKPQGPPAQGGSKSQSARS 123
                           P    +R P  P  PG P GP    G+P  P ++G + ++    
Sbjct: 393 QPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPG 452

Query: 124 PPG--KPQGPPQQEG-NNPQGPPPPAG--GNPQQPQAP-----PAGQPQGPPRPPQGGRP 173
           P G   P GP  +EG    +G P P G  G P +   P     P       P+ P G R 
Sbjct: 453 PVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERG 512

Query: 174 SRPP 177
           S  P
Sbjct: 513 SPGP 516



 Score = 58.5 bits (140), Expect = 3e-09
 Identities = 51/139 (36%), Positives = 58/139 (41%), Gaps = 26/139 (18%)

Query: 36   PQGP-SPQGGNKPQGPPPPPGKPQGPPPQG-----GNKP----QGPP-PPGKPQGPPPQG 84
            P GP  P G   P GP  P G       QG     G++     QGPP PPG P    P G
Sbjct: 1074 PAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSG 1133

Query: 85   DKS-RSPRSPPGKPQGPPPQG--GKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQG 141
                  PR PPG    P   G  G P GP    G + ++  + P  P GPP      P G
Sbjct: 1134 ASGPAGPRGPPGSAGAPGKDGLNGLP-GPIGPPGPRGRTGDAGPVGPPGPP-----GPPG 1187

Query: 142  PP-PPAGG-----NPQQPQ 154
            PP PP+ G      PQ PQ
Sbjct: 1188 PPGPPSAGFDFSFLPQPPQ 1206



 Score = 57.8 bits (138), Expect = 5e-09
 Identities = 51/181 (28%), Positives = 57/181 (31%), Gaps = 34/181 (18%)

Query: 29  PSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP------- 81
           PS   G    P  +G   P GP  P G    P   G     G P     QG P       
Sbjct: 672 PSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPG 731

Query: 82  ---------PQGDKSRSPRSPPGKPQGPPPQGGK----PQGPPAQGGSKSQSARSPPGKP 128
                    P+GD  R    P G    P   G +    P GPP   G+      S P  P
Sbjct: 732 ERGAAGLPGPKGD--RGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGP 789

Query: 129 QGPPQQEG----NNPQGPPPPAG--------GNPQQPQAPPAGQPQGPPRPPQGGRPSRP 176
            GP    G        GPP PAG        G P     P     +G   PP    P+ P
Sbjct: 790 AGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGP 849

Query: 177 P 177
           P
Sbjct: 850 P 850



 Score = 54.7 bits (130), Expect = 4e-08
 Identities = 53/166 (31%), Positives = 61/166 (36%), Gaps = 45/166 (27%)

Query: 49  GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGG--- 105
           G   P G+     P G   P      G      P+GD    PR P G P GPP + G   
Sbjct: 83  GAEVPEGECCPVCPDGSESPTDQETTGVEG---PKGDTG--PRGPRG-PAGPPGRDGIPG 136

Query: 106 -----------KPQGPPAQGGS-----------KSQSARSPPGKPQGPPQQEG-NNPQGP 142
                       P GPP  GG+           KS    S PG P GP    G   P G 
Sbjct: 137 QPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPG-PMGPSGPRGLPGPPGA 195

Query: 143 PPPAG-----GNPQQPQAPPAGQPQGPPRPP-------QGGRPSRP 176
           P P G     G P +P A     P+GPP PP       + G+P RP
Sbjct: 196 PGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRP 241



 Score = 52.8 bits (125), Expect = 2e-07
 Identities = 56/177 (31%), Positives = 64/177 (36%), Gaps = 44/177 (24%)

Query: 34  GNPQGPSPQGGNKPQGPPPPPGKP--QGPP-------PQGGNKP---------QGPPPPG 75
           G    P  QG   P GPP   GKP  QG P       P G             QGPP P 
Sbjct: 635 GPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPA 694

Query: 76  KPQGP--PPQGDKSRSPRSPPGKP--QGPPPQGGKP--------QGPPA-QGGSKSQSAR 122
            P+G    P  D ++     PG P  QG P   G P         GP   +G +  + A 
Sbjct: 695 GPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGAD 754

Query: 123 SPPGK--------PQGPPQQEG----NNPQGPPPPAGGNPQQPQAPPAGQPQGPPRP 167
             PGK        P GPP   G        GP  PAG    +      G+P GPP P
Sbjct: 755 GSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEP-GPPGP 810



 Score = 42.0 bits (97), Expect = 3e-04
 Identities = 29/91 (31%), Positives = 32/91 (35%), Gaps = 18/91 (19%)

Query: 34   GNPQGPSPQGGNKPQGPPPPPGK--------------PQGPPPQGGNK----PQGPPPPG 75
            G+P    P G + P GP  PPG               P GPP   G      P GPP P 
Sbjct: 1124 GSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPP 1183

Query: 76   KPQGPPPQGDKSRSPRSPPGKPQGPPPQGGK 106
             P GPP            P  PQ     GG+
Sbjct: 1184 GPPGPPGPPSAGFDFSFLPQPPQEKAHDGGR 1214



 Score = 41.2 bits (95), Expect = 5e-04
 Identities = 31/84 (36%), Positives = 36/84 (42%), Gaps = 16/84 (19%)

Query: 26   EESPSLIAG--NPQGPSPQGGNK----------PQGPPPPPGKPQGPPPQGGNKPQGPPP 73
            E+ PS  +G   P+GP    G            P GPP P G+     P G   P GPP 
Sbjct: 1128 EQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVG---PPGPPG 1184

Query: 74   PGKPQGPPPQG-DKSRSPRSPPGK 96
            P  P GPP  G D S  P+ P  K
Sbjct: 1185 PPGPPGPPSAGFDFSFLPQPPQEK 1208


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.303    0.135    0.430 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,685,193
Number of Sequences: 37866
Number of extensions: 1966240
Number of successful extensions: 77740
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 2142
Number of HSP's successfully gapped in prelim test: 2149
Number of HSP's that attempted gapping in prelim test: 8757
Number of HSP's gapped (non-prelim): 24563
length of query: 178
length of database: 18,247,518
effective HSP length: 96
effective length of query: 82
effective length of database: 14,612,382
effective search space: 1198215324
effective search space used: 1198215324
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.7 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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