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Search of human proteins with 41281612
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|41281612 zinc finger protein 828 [Homo sapiens]
(812 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|41281612 zinc finger protein 828 [Homo sapiens] 1691 0.0
gi|163965366 nascent polypeptide-associated complex alpha subuni... 127 3e-29
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 118 3e-26
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens] 112 1e-24
gi|110349719 titin isoform N2-A [Homo sapiens] 110 7e-24
gi|47132519 Ras association and pleckstrin homology domains 1 is... 107 4e-23
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 99 1e-20
gi|150170670 piccolo isoform 2 [Homo sapiens] 99 2e-20
gi|150378539 piccolo isoform 1 [Homo sapiens] 99 2e-20
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 99 2e-20
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 99 2e-20
gi|40807475 PML-RARA regulated adaptor molecule 1 [Homo sapiens] 98 4e-20
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 97 8e-20
gi|222352122 hypothetical protein LOC284297 [Homo sapiens] 96 2e-19
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 96 2e-19
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 96 2e-19
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 95 3e-19
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 95 3e-19
gi|116284392 mucin 2 precursor [Homo sapiens] 94 7e-19
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 92 2e-18
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 91 3e-18
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 88 4e-17
gi|31324577 molecule interacting with Rab13 [Homo sapiens] 87 5e-17
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 87 8e-17
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 87 8e-17
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 87 8e-17
gi|160707881 formin 2 [Homo sapiens] 86 1e-16
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 85 2e-16
gi|112421108 capicua homolog [Homo sapiens] 85 2e-16
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 84 4e-16
>gi|41281612 zinc finger protein 828 [Homo sapiens]
Length = 812
Score = 1691 bits (4380), Expect = 0.0
Identities = 812/812 (100%), Positives = 812/812 (100%)
Query: 1 MEAFQELRKPSARLECDHCSFRGTDYENVQIHMGTIHPEFCDEMDAGGLGKMIFYQKSAK 60
MEAFQELRKPSARLECDHCSFRGTDYENVQIHMGTIHPEFCDEMDAGGLGKMIFYQKSAK
Sbjct: 1 MEAFQELRKPSARLECDHCSFRGTDYENVQIHMGTIHPEFCDEMDAGGLGKMIFYQKSAK 60
Query: 61 LFHCHKCFFTSKMYSNVYYHITSKHASPDKWNDKPKNQLNKETDPVKSPPLPEHQKIPCN 120
LFHCHKCFFTSKMYSNVYYHITSKHASPDKWNDKPKNQLNKETDPVKSPPLPEHQKIPCN
Sbjct: 61 LFHCHKCFFTSKMYSNVYYHITSKHASPDKWNDKPKNQLNKETDPVKSPPLPEHQKIPCN 120
Query: 121 SAEPKSIPALSMETQKLGSVLSPESPKPTPLTPLEPQKPGSVVSPELQTPLPSPEPSKPA 180
SAEPKSIPALSMETQKLGSVLSPESPKPTPLTPLEPQKPGSVVSPELQTPLPSPEPSKPA
Sbjct: 121 SAEPKSIPALSMETQKLGSVLSPESPKPTPLTPLEPQKPGSVVSPELQTPLPSPEPSKPA 180
Query: 181 SVSSPEPPKSVPVCESQKLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPP 240
SVSSPEPPKSVPVCESQKLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPP
Sbjct: 181 SVSSPEPPKSVPVCESQKLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPP 240
Query: 241 SASSPESPVLAASPEPWGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPEP 300
SASSPESPVLAASPEPWGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPEP
Sbjct: 241 SASSPESPVLAASPEPWGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPEP 300
Query: 301 RRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWK 360
RRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWK
Sbjct: 301 RRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWK 360
Query: 361 PTPSVSSASWKSSSVSPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPELR 420
PTPSVSSASWKSSSVSPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPELR
Sbjct: 361 PTPSVSSASWKSSSVSPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPELR 420
Query: 421 KPGPPLSPEIRSPAGSPELRKPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGSPDLW 480
KPGPPLSPEIRSPAGSPELRKPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGSPDLW
Sbjct: 421 KPGPPLSPEIRSPAGSPELRKPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGSPDLW 480
Query: 481 KSSFFIEPQKPVFPETRKPGPSGPSESPKAASDIWKPVLSIDTEPRKPALFPEPAKTAPP 540
KSSFFIEPQKPVFPETRKPGPSGPSESPKAASDIWKPVLSIDTEPRKPALFPEPAKTAPP
Sbjct: 481 KSSFFIEPQKPVFPETRKPGPSGPSESPKAASDIWKPVLSIDTEPRKPALFPEPAKTAPP 540
Query: 541 ASPEARKRALFPEPRKHALFPELPKSALFSESQKAVELGDELQIDAIDDQKCDILVQEEL 600
ASPEARKRALFPEPRKHALFPELPKSALFSESQKAVELGDELQIDAIDDQKCDILVQEEL
Sbjct: 541 ASPEARKRALFPEPRKHALFPELPKSALFSESQKAVELGDELQIDAIDDQKCDILVQEEL 600
Query: 601 LASPKKLLEDTLFPSSKKLKKDNQESSDAELSSSEYIKTDLDAMDIKGQESSSDQEQVDV 660
LASPKKLLEDTLFPSSKKLKKDNQESSDAELSSSEYIKTDLDAMDIKGQESSSDQEQVDV
Sbjct: 601 LASPKKLLEDTLFPSSKKLKKDNQESSDAELSSSEYIKTDLDAMDIKGQESSSDQEQVDV 660
Query: 661 ESIDFSKENKMDMTSPEQSRNVLQFTEEKEAFISEEEIAKYMKRGKGKYYCKICCCRAMK 720
ESIDFSKENKMDMTSPEQSRNVLQFTEEKEAFISEEEIAKYMKRGKGKYYCKICCCRAMK
Sbjct: 661 ESIDFSKENKMDMTSPEQSRNVLQFTEEKEAFISEEEIAKYMKRGKGKYYCKICCCRAMK 720
Query: 721 KGAVLHHLVNKHNVHSPYKCTICGKAFLLESLLKNHVAAHGQSLLKCPRCNFESNFPRGF 780
KGAVLHHLVNKHNVHSPYKCTICGKAFLLESLLKNHVAAHGQSLLKCPRCNFESNFPRGF
Sbjct: 721 KGAVLHHLVNKHNVHSPYKCTICGKAFLLESLLKNHVAAHGQSLLKCPRCNFESNFPRGF 780
Query: 781 KKHLTHCQSRHNEEANKKLMEALEPPLEEQQI 812
KKHLTHCQSRHNEEANKKLMEALEPPLEEQQI
Sbjct: 781 KKHLTHCQSRHNEEANKKLMEALEPPLEEQQI 812
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 127 bits (320), Expect = 3e-29
Identities = 139/463 (30%), Positives = 188/463 (40%), Gaps = 57/463 (12%)
Query: 103 TDPVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKPTPLTPLEPQKPGSV 162
T P +PP P+ P + PK T P SPK +P P G+
Sbjct: 1010 TPPAVTPPSPKGS--PAATPFPKGASTPPAAT--------PPSPKGSPAA--TPLPKGAP 1057
Query: 163 VSPELQTPLPSPEPSKPASVSSPEPPKSVPVC-ESQKLAPVPSPEPQKPAPVSPESVKAT 221
+P P P P+ P+ +P PP + P + P P P PA +P S K
Sbjct: 1058 TTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPA-ATPPSPKGG 1116
Query: 222 LSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWG--PSPAASPESRKSARTTSPEPR 279
L+ P P K + P T P+A+ P A+P P G +PAA+P S K T P
Sbjct: 1117 LATP-PHKGA--PTT---PAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKG 1170
Query: 280 KP-SPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAK 338
P +P+ +P P+ P+P +P + PP SP+ + PS P PA
Sbjct: 1171 APTTPAATP------PSPKGGLATPSPKGAPTTPAATPP-SPKGGLATPSPKGAPTTPAA 1223
Query: 339 PAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVSP---SSWKSPPASPESWKSG-- 393
PS G P P +P TP+ + S K +P + P A+P S K G
Sbjct: 1224 TPPSPKGGLATPSPKGAP----TTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLA 1279
Query: 394 -PPELRKTAP---TLSPEHWKAVPPVSPELRKPGPPLSPEIRSPAGSPELRKPSGSPDLW 449
PP K AP ++P K P SP P PP + SP GSP P G+P
Sbjct: 1280 TPP--HKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATP-PSPKGSPGTPPPKGAPTPP 1336
Query: 450 KLSPDQRKTSPASLDFPESQKSSRGGSPDLWKSSFFIEPQKPVFPETRKPGPSGPSESPK 509
++P K +P P + SS+GG S P P + K GP+ SPK
Sbjct: 1337 AVTPPSPKGTPT---LPATTPSSKGGPT---TPSSKEGPTPPAATPSHKGGPAMTPPSPK 1390
Query: 510 AASDIWKPVLSIDTEPRKPALFPEPAKTAPPASPEARKRALFP 552
I P +P PA+ P K A PA+P R+ A P
Sbjct: 1391 RGPAIPSP----KGDPTSPAVIPLSPKKA-PATPVTREGAATP 1428
Score = 116 bits (290), Expect = 1e-25
Identities = 140/506 (27%), Positives = 192/506 (37%), Gaps = 65/506 (12%)
Query: 105 PVKSPPLP---EHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKP-TPLTPLEPQKP- 159
PV S P E ++ ++ L+ LG +SP++ +P T P P
Sbjct: 762 PVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPI 821
Query: 160 ---GSVVSPELQTPLPSPEPS------KPASVSSPEPPKSVPVCESQKLAPVPSPEPQKP 210
S VSP + LP S PA+ SP PP +P +P P
Sbjct: 822 GNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPP-----------SPKGAPTPSAV 870
Query: 211 APVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEP-WGPSPAASPESRK 269
P+SP+ V P K++ P + P E P A+P P P+ + + S K
Sbjct: 871 TPLSPKGVTL------PPKETPTPSVVNLPFPK--EGP---ATPAPKQAPALSMTSSSPK 919
Query: 270 SARTT-SPE--PRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPG----SPRP 322
AR T +P+ P PSP +P P PA +P + PA W P PP SP+
Sbjct: 920 KARATPAPKGIPASPSPKGAPTP----PAATPPSPKGGPATPSPKWAPTPPAATPPSPKG 975
Query: 323 WKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKS 382
+ PS P PA PS GP P P +P P TP S ++ +
Sbjct: 976 GPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTP 1035
Query: 383 PPASPESWKSGP--PELRKTAPTLSPEHWKAVP---PVSPELRKPGPPLSPEIRSPAGSP 437
P A+P S K P L K APT +P P P +P L+ P + SP G P
Sbjct: 1036 PAATPPSPKGSPAATPLPKGAPT-TPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGP 1094
Query: 438 ELRKPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGSPDLWKSSFFIEPQK--PVFPE 495
P G+P +P K A+ + ++ +P K P K P P
Sbjct: 1095 ATPSPKGAPMPPAATPPSPKGGLATPPH-KGAPTTPAATPPSPKGGLATPPPKGAPTTPA 1153
Query: 496 TRKPGPSGPSESPKAASDIWKPVLSIDTEPRKPALFPEP--AKTAPPASPEARKRAL-FP 552
P P G +P P + P+ P P A T P A+P + K L P
Sbjct: 1154 ATPPSPKGGLATPPPKGAPTTPA-ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATP 1212
Query: 553 EPR----KHALFPELPKSALFSESQK 574
P+ A P PK L + S K
Sbjct: 1213 SPKGAPTTPAATPPSPKGGLATPSPK 1238
Score = 115 bits (289), Expect = 1e-25
Identities = 126/493 (25%), Positives = 182/493 (36%), Gaps = 65/493 (13%)
Query: 103 TDPVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKPTPLTPLE------- 155
T P +PP P+ + + PA + + K G L+ SPK P TP
Sbjct: 1173 TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG--LATPSPKGAPTTPAATPPSPKG 1230
Query: 156 ----PQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQKPA 211
P G+ +P P P P+ P +P PP + P LA P PA
Sbjct: 1231 GLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPA 1290
Query: 212 PVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEP---WGPSPAASPESR 268
V+P S K + P+ P P SP +P +P P PSP +P
Sbjct: 1291 VVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLP 1350
Query: 269 KSARTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGP------------ 316
+ ++ P PS E P P PA +P + PA++P S K GP
Sbjct: 1351 ATTPSSKGGPTTPSSKEGPTP----PAATPS-HKGGPAMTPPSPKRGPAIPSPKGDPTSP 1405
Query: 317 ---PGSPRPWKSNPSASSGPWKPAK---PAPSVSPGPWKPIPSVSPGPWKPTPSVSSASW 370
P SP+ + P G P+K P+V+P K P+ S P S
Sbjct: 1406 AVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDP 1465
Query: 371 KSSSVSPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPELRKPGPPLSPEI 430
+V+P S K PPA + S P +K T +P +P V P K P
Sbjct: 1466 TLPAVTPPSPKEPPAPKQVATSSSP--KKAPATPAPMGAPTLPAVIPSSPKEVPATPSSR 1523
Query: 431 RSPAG---------SPELRKPSGS---PDLWKLSPDQRKTSPASLDFPESQKSSRGGSPD 478
R P +P P + P + SP + P + P + S SP
Sbjct: 1524 RDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPP 1583
Query: 479 LWKSSFF---IEPQKPVFPETRKPGPSGPSESPKAASDIWKPVLSIDTEPRKPAL-FPEP 534
S + P++ + P P+ S SPK A P ++ + + PA P+
Sbjct: 1584 AVTPSTYKGAPSPKELLIP------PAVTSPSPKEAPT--PPAVTPPSPEKGPATPAPKG 1635
Query: 535 AKTAPPASPEARK 547
T+PP +P + K
Sbjct: 1636 TPTSPPVTPSSLK 1648
Score = 114 bits (284), Expect = 5e-25
Identities = 134/467 (28%), Positives = 188/467 (40%), Gaps = 53/467 (11%)
Query: 141 LSPESPKPTPLTPLEPQKPGS-----VVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCE 195
L P + + P+ P PQ + V++PE+ P P PS P + + P K +
Sbjct: 700 LVPTASENCPVAP-SPQNTCAPLATLVLAPEI--PKSVPSPSLPPAGTPPGTKKVDGISH 756
Query: 196 SQKLAPVPSPEPQKPAPVSPESV----KATLS----NPKPQKQSHFPETLGPPS---ASS 244
+ LAPV S + P S S K TL+ +P P S P+T PP+ ++
Sbjct: 757 TSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAG 816
Query: 245 PESPVLAASPEPWGPSPAA-SPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPEPRRP 303
P++P+ S P P A+ PE+ + S + K SP+ + P P P +P P
Sbjct: 817 PDTPIGNLS-SPVSPVEASFLPEN-----SLSFQGSKDSPATTHSPTPPSPKGAPTPSAV 870
Query: 304 APAVSPGSWKPGPPGSPRPWKSN-PSASSGPWKPA-KPAPSVSPGPWKPIPSVSPGPWKP 361
P G P P +P P N P GP PA K AP++S + S SP +
Sbjct: 871 TPLSPKGVTLP-PKETPTPSVVNLPFPKEGPATPAPKQAPALS------MTSSSPKKARA 923
Query: 362 TPSVSSASWKSSSVSPSSWKSPP-ASPESWKSGP----PELRKTAPTLSPEHWKAVPPVS 416
TP+ +S SP +PP A+P S K GP P+ T P +P K P
Sbjct: 924 TPAPKGI---PASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATP 980
Query: 417 PELRKPGPPLSPEIRSPAGSPELRKPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGS 476
P PP + SP G P P G+P ++P K SPA+ FP+ + +
Sbjct: 981 SPKGAPTPPAATP-PSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAAT 1039
Query: 477 PDLWKSSFFIEP---QKPVFPETRKPGPSGPSESPKAASDIWKPVLSIDTEPRKPAL-FP 532
P K S P P P P P G +P P + + PA P
Sbjct: 1040 PPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSP 1099
Query: 533 EPAKTAPPASPEARKRALFPEPRK-----HALFPELPKSALFSESQK 574
+ A P A+P + K L P K A P PK L + K
Sbjct: 1100 KGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPK 1146
Score = 107 bits (267), Expect = 4e-23
Identities = 150/616 (24%), Positives = 231/616 (37%), Gaps = 77/616 (12%)
Query: 95 PKNQLNKETDPVKSPPLPEHQKIPCNSA-EPKSIPAL-SMETQKLGSVLSPESPKPTPLT 152
P +KE P P H+ P + PK PA+ S + + P SPK P T
Sbjct: 1360 PTTPSSKE-GPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPAT 1418
Query: 153 PLEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQKPAP 212
P+ + + +L P +P K A +S PK P S K P P P+P
Sbjct: 1419 PVTREGAATPSKGDLTPPAVTPVSLKKAPATSA--PKGGPATPSSKGDPT-LPAVTPPSP 1475
Query: 213 VSPESVKATLSNPKPQKQSHFPETLGPPSA-----SSPESPVLAASPEPWGPSPAASPES 267
P + K ++ P+K P +G P+ SSP+ S +P A+ S
Sbjct: 1476 KEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLS 1535
Query: 268 RKSARTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPA----------PAVSPGSWKPGPP 317
+K+ T +P+ P+ + K PA+ PA PAV+P ++K P
Sbjct: 1536 KKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAP- 1594
Query: 318 GSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVSP 377
SP+ P+ +S K A P+V+P PS GP P P + S V+P
Sbjct: 1595 -SPKELLIPPAVTSPSPKEAPTPPAVTP------PSPEKGPATPAPKGTPTS---PPVTP 1644
Query: 378 SSWKSPPASPES--WKSGP--PELRKTAPTLSPEHWKAVPPVSPELRKPGPPLSPEIRSP 433
SS K P SP S K G P+ K P K + L P P +P I +P
Sbjct: 1645 SSLKDSPTSPASVTCKMGATVPQASKGLPAK-----KGPTALKEVLVAPAPESTPIITAP 1699
Query: 434 A-GSPELRKPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGSPDLWKSSFFIEPQKPV 492
P+ +K S TSP P ++ S+G S+ P PV
Sbjct: 1700 TRKGPQTKKSSA-------------TSPPICPDPSAKNGSKGP-----LSTVAPAPLLPV 1741
Query: 493 FPETRKP--------GPSGPSESPKAASDIWKPVLSIDTEPRKPALFPEPAKTAPPASPE 544
++ K P GP P++ + + + KP A +PP S
Sbjct: 1742 QKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLP 1801
Query: 545 ARKRALFPEPRKHALFPELPKSALFSESQKAVELGDELQIDAIDDQKCD--ILVQEEL-- 600
+ P K P P L S S+ ++ + I + + Q L
Sbjct: 1802 LAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVN 1861
Query: 601 LASPKKLLEDTLFPSSKKLKKDNQESSDAELSSSEYIKTDLDAMDIKGQESSSDQ----E 656
+ +PK PS+K+ N + S E S E + +L+ D + Q
Sbjct: 1862 MPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESV-PELEEQDSTQATTQQAQLAAAA 1920
Query: 657 QVDVESIDFSKENKMD 672
++D E + +K+++ +
Sbjct: 1921 EIDEEPVSKAKQSRSE 1936
Score = 68.6 bits (166), Expect = 2e-11
Identities = 142/574 (24%), Positives = 203/574 (35%), Gaps = 137/574 (23%)
Query: 108 SPPLPEHQKIPCNSAEPKSIPA---LSMETQK-LGSVLSPESPKPTPLTPLEP---QKPG 160
SPPLP+ + + K++P+ + TQK L +V P S + P +P + K
Sbjct: 506 SPPLPDPEDL-------KNLPSSVLVKFPTQKDLQTV--PASLEGAPFSPAQAGLTTKKD 556
Query: 161 SVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQKPAP--VSPESV 218
V P +Q P PS ++ SSPE P S ++K P P KPA SP V
Sbjct: 557 PTVLPLVQAA-PKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLP-IGKPASSMTSPLGV 614
Query: 219 KATLSNPKPQKQSHFPETLGPPSASSPESPVLAASP----EPWGPSPAASPESRKSARTT 274
++ S K + P++ GP SS +P +AA P +P G +P + + T
Sbjct: 615 NSSASVIKTDSYAG-PDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTA 673
Query: 275 SPE--------------------------------PRKPSPSESPEPWKPFPAVSPEPRR 302
SP P PSP + P P+
Sbjct: 674 SPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKS 733
Query: 303 -PAPAVSPGSWKPG-------------PPGSPRPWKSNPSASSGPWKPA----------- 337
P+P++ P PG P + P K P+ SG A
Sbjct: 734 VPSPSLPPAGTPPGTKKVDGISHTSALAPVASSP-KECPTEDSGASATASSKGTLTYLAD 792
Query: 338 KPAP---SVSP------------GPWKPIPSVSPGPWKPTPS----VSSASWKSSSVSPS 378
P+P SVSP GP PI ++S P P + +S S++ S SP+
Sbjct: 793 SPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLS-SPVSPVEASFLPENSLSFQGSKDSPA 851
Query: 379 SWKSP-PASPES--WKSGPPELRKTAPTLSPEHWKAVPPVSPELRKPGPPLSPEIRSPA- 434
+ SP P SP+ S L TL P+ V+ K GP ++PA
Sbjct: 852 TTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPAL 911
Query: 435 -----------------GSPELRKPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGSP 477
G P P G+P +P K PA+ P+ + +P
Sbjct: 912 SMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPAT-PSPKWAPTPPAATP 970
Query: 478 DLWKSSFFIEPQK--PVFPETRKPGPSGPSESPKAASDIWKPVLSIDTEPRKPAL--FPE 533
K K P P P P G +P P ++ + PA FP+
Sbjct: 971 PSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPK 1030
Query: 534 PAKTAPPASPEARKRALFPEPRKHALFPELPKSA 567
A T P A+P P P+ LPK A
Sbjct: 1031 GASTPPAATP--------PSPKGSPAATPLPKGA 1056
Score = 51.2 bits (121), Expect = 4e-06
Identities = 79/322 (24%), Positives = 118/322 (36%), Gaps = 28/322 (8%)
Query: 115 QKIPCNSAEPKSIPALSMETQKLGSVLSPESPKPTPLTPLEPQKPGSVVSPELQTPLPSP 174
Q++P AE +P +S ++ P P P +P Q P S + P PS
Sbjct: 14 QELPQPQAETAVLP-MSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPST 72
Query: 175 EPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFP 234
S P V P+ + L P P + P A L+ P P
Sbjct: 73 IASTPLEVPFPQSSSGTAL----PLGTAPEAPTFLPNLIGPPISPAALALASPMIA---P 125
Query: 235 ETLGPPSASSPESPVLAASPEPWGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKPFP 294
G PS+S+P + ++A +P S A P TSP + S S P
Sbjct: 126 TLKGTPSSSAPLA-LVALAPHSVQKSSAFPPN-----LLTSPPSVAVAESGSVITLSA-P 178
Query: 295 AVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSV 354
EP+ V P P P G+P P S+ P+ P S+ G +P
Sbjct: 179 IAPSEPKTNLNKV-PSEVVPNPKGTPSP---PCIVSTVPYHCVTPMASIQSGV-ASLPQT 233
Query: 355 SPGPWKPTPSVSSASWKSSSVSPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPP 414
+ PT +++ AS + + SS P +P S P A +LS + ++P
Sbjct: 234 T-----PTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQ---SLPV 285
Query: 415 VSPELRKPGPPLSPEIRSPAGS 436
V+ + GP P+ GS
Sbjct: 286 VTSSQKTAGPNTPPDFPISLGS 307
Score = 38.5 bits (88), Expect = 0.025
Identities = 119/534 (22%), Positives = 178/534 (33%), Gaps = 119/534 (22%)
Query: 126 SIPALSMETQKLGSVLSPESPKPTPLTPLEPQKPGSVVSPELQTPLPSPEPSKPASVSSP 185
++ +S++ G+ + PL P +V + + P PS +S++
Sbjct: 335 TVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITC- 393
Query: 186 EPPKSVPVCESQKLAPVPS------PEPQKPAPVSPE----SVKAT---LSNP-----KP 227
P S+ V S L+P S P P+ + SV T ++NP P
Sbjct: 394 SPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAP 453
Query: 228 QKQSHFPETLGPPSASSPESPVLAASPEPWGPSPAASPESRKSARTTSPEPRKPSPSESP 287
+ PP +S P S + SP +P A E TT P P P P
Sbjct: 454 TTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSP-PLPDP 512
Query: 288 EPWKPFPA----------------VSPEPRRPAPAVSPGSWKPGP------PGSPRPWKS 325
E K P+ S E +PA + + K P +P+ S
Sbjct: 513 EDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPS 572
Query: 326 NPSASSGPWKPAKPAPSV---SPGPWKPIPSVSPGPWKPTPSVSSAS------------- 369
S SS P P P ++ S G PI + P SSAS
Sbjct: 573 FQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSA 632
Query: 370 ---WKSSSVSPSSWKSPPASPESWKSGPPELRKTAP-------------TLSPEHWKA-- 411
KSS ++P+ P S + P + T+ +L+P++
Sbjct: 633 GPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKE 692
Query: 412 --------VP------PVSPELRKPGPP-----LSPEIRSPAGSPELRKPSGSPDLWKLS 452
VP PV+P + P L+PEI SP L P+G+P K
Sbjct: 693 GTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSL-PPAGTPPGTKKV 751
Query: 453 PDQRKTS---PASLDFPESQKSSRGGSPDLWKS---SFFIEPQKP----VFPETRKP--- 499
TS P + E G S ++ + P V P+T++P
Sbjct: 752 DGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTK 811
Query: 500 -GPSGPSE---------SPKAASDIWKPVLSIDTEPRKPALFPEPAKTAPPASP 543
G +GP SP AS + + LS PA P +P +P
Sbjct: 812 KGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAP 865
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 118 bits (295), Expect = 3e-26
Identities = 151/557 (27%), Positives = 201/557 (36%), Gaps = 76/557 (13%)
Query: 64 CHKCFF-----TSKMYSNVYYHITSKHASPDKWNDKPKNQLNKETDPVKSPPLPEHQKIP 118
CH+C T + + + + S+ + P+ D P ++ + + P H
Sbjct: 346 CHRCHKAQGGQTIRSVAEQHTPVCSRFSPPEP-GDTPTDEPDALYVACQGQPKGGH---- 400
Query: 119 CNSAEPKSIPALSMETQKLGSV-----------LSPESP--KPTPLTPLEPQKPGSVVSP 165
S +PK L E + LG L+ E P P +PL P S SP
Sbjct: 401 VTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSP 460
Query: 166 ELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQKPAPVS-PESV--KATL 222
+ SP P + + PE E L+P P P P P S P S ++ L
Sbjct: 461 PPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPL 520
Query: 223 SNPKPQKQSHFPET-LGPPSASSPESPVLAASP-EPWGPSPAASPESRKSARTTSPE--P 278
S P+ S ET L PP +SP SP SP P SP S + PE P
Sbjct: 521 SPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESP 580
Query: 279 RKPSPSESP-----EPWKPFPAVSPEPRRPAPAVSPGSWKP-----GPPGSPRPWKSNPS 328
P P ESP E + FP P P P SP S P PP P P
Sbjct: 581 MSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPE 640
Query: 329 ASSGPWKPAKPAPSVSPGP----WKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPP 384
S P P +SP P P P SP P S +S ++S +SP SP
Sbjct: 641 ES--PMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPT 698
Query: 385 ASPESWKSGPPELRKTAPTLSPEHWKAVP-PVSPEL--RKPGPPLSPEIRSPAGSPELRK 441
+ P P + +L E +P P P+L R GP LSP P SP +
Sbjct: 699 SPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEE 758
Query: 442 PSGSPDLWKLSPDQRKTSPASLDFPES-QKSSRGGSPDLWKSSFFIEPQKPVFPETRKPG 500
P SP + + P PE S + P L P
Sbjct: 759 PHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHL------------------SPQ 800
Query: 501 PSGPSESPKAASDIWKPVLSIDTEPRKPALFPEPAKTAPPASPEARKRALFPEPRKHALF 560
P SP+ PV P +P L P+P ++ SP++ + L P P + L
Sbjct: 801 PEELHLSPQTEEPHLSPV------PEEPCLSPQPEES--HLSPQSEEPCLSPRPEESHLS 852
Query: 561 PELPKSALFSESQKAVE 577
PEL K L +K E
Sbjct: 853 PELEKPPLSPRPEKPPE 869
Score = 92.0 bits (227), Expect = 2e-18
Identities = 128/456 (28%), Positives = 173/456 (37%), Gaps = 74/456 (16%)
Query: 110 PLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKPTPLTP---LEPQKPGSVVSPE 166
P PE + + EP LS + ++ PE P +P L PQ +SP+
Sbjct: 754 PRPEEPHLSPQAEEPH----LSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQ 809
Query: 167 LQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVP-----SPEPQKPAPVSPESVKAT 221
+ P SP P +P PE P E L+P P SPE +KP P+SP K
Sbjct: 810 TEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKP-PLSPRPEKPP 868
Query: 222 LSN---PKPQKQSHFP--------ETLGPPSASSPESPVLAASPEPWGPSPAASPESRKS 270
P P++ FP LG P+ S P P L+ PE SP+ P
Sbjct: 869 EEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEP----- 923
Query: 271 ARTTSPEPRKPSPSESPEPWKPF------PAVSPEPRRPAPAVSPGSWKP-GPPGSP--- 320
+ SP+ P P P P P PA+SP P + G P P +P
Sbjct: 924 --SLSPQLMPPDP--LPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILE 979
Query: 321 RPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSV---SP 377
P P A+ +P P + P P P+ SP +P P S + S V SP
Sbjct: 980 TPISPPPEANCTDPEPVPPM-ILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSP 1038
Query: 378 SSWKSPPASPESWKSGPPELRKT------APTLSPEHWKAVPPVSPELRKPGPPLSPEIR 431
S SPPA P S S + K A E K P P L P + +
Sbjct: 1039 PSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALE---PSATSPLP 1095
Query: 432 SPAGSPELRKPSGSPDLWKLSPDQRKTSPA-SLDFPESQKSSRGGSP-----DLWKSSFF 485
SP G PS +P L S T+P +D P SQ G +P +L S
Sbjct: 1096 SPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEP-GQTPGSLASELKGSPVL 1154
Query: 486 IEPQK-------PVFPETRKP----GPSGPSESPKA 510
++P++ V+PE ++ P E P+A
Sbjct: 1155 LDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRA 1190
Score = 68.2 bits (165), Expect = 3e-11
Identities = 117/484 (24%), Positives = 169/484 (34%), Gaps = 76/484 (15%)
Query: 116 KIPCNSAEPKSIPALSMETQKLGSVLSPESPKPT----PLTPLEPQ--KPGSVVSPELQT 169
K P P + A +E Q G L P+ P P P P P +PGS P Q
Sbjct: 2322 KTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQP 2381
Query: 170 PL-PSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQKPAPVSPESVKATLSNPK-- 226
PL P P+P P S + PP+S+P ++ P + +P++P + A P
Sbjct: 2382 PLTPRPQPPPPESCCA-LPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPV 2440
Query: 227 -PQKQSHFPETLGP--PSASSPESPVLAASPEPWGPSPA--------------------- 262
P+ QS P + P P + P +P L P P P A
Sbjct: 2441 TPRFQSPDPYSRPPSRPQSRDPFAP-LHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALP 2499
Query: 263 ASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPEPRR---PAPAVSPGSWKPGP-PG 318
A P A+ S +P P+ P +P P R P P P P PG
Sbjct: 2500 AGPAGELHAKVPSGQP----PNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPG 2555
Query: 319 SPRPWKSNPSASSGP--WKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVS 376
P P N GP KP +V+ G + P S P P+ + S+ S +
Sbjct: 2556 LPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHP----SGSPLGPSSGSTGESYGLSPLR 2611
Query: 377 PSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVS----------PELRKPGPPL 426
P S PPA S + + SP + P P + PG
Sbjct: 2612 PPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPG--- 2668
Query: 427 SPEIRSPAGSPELRKPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRG--GSPDLWKSSF 484
S EL K L +L Q+ E+ ++ G G P W +
Sbjct: 2669 ----MSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGA-- 2722
Query: 485 FIEPQKPVFPETRKPGPSGPSESPKAASDIWKPVLSIDTEPRKPALFPEP---AKTAPPA 541
EP P F + + G + + + +S + P + P FP ++ PPA
Sbjct: 2723 --EPSSPAFEQLSR-GQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPA 2779
Query: 542 SPEA 545
+P +
Sbjct: 2780 TPSS 2783
Score = 67.4 bits (163), Expect = 5e-11
Identities = 117/486 (24%), Positives = 166/486 (34%), Gaps = 89/486 (18%)
Query: 145 SPKPTPLTPLEPQKPGSVVSPELQTPLPSP--EPSKPASVSSPEPPKSVPVCESQKLAP- 201
S P L P P +P +P P PSP P++P + + P + E P
Sbjct: 2173 SQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPG 2232
Query: 202 VPSPEPQKPAP------------VSPES-------VKATLSNPKPQKQSH---------- 232
P +P P P PES L +P P +S
Sbjct: 2233 TPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEEL 2292
Query: 233 --FPETLGPPSASSPESPVLAASPEPWGPSPAASPESRK---SARTTSPEPRKPSPSESP 287
+ GPP+ +SP +S G +P+ K + R + EP+ P P
Sbjct: 2293 GASSPSYGPPNLGFVDSP---SSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRP 2349
Query: 288 EPWKPFPAVSPEPRRPAPAVSPGSWK---PGPPGSPRPWKSNPSASSGPWKPAKPAPSVS 344
+ P A++P P PGS+ PP +PRP P + A P S+
Sbjct: 2350 QEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCC-----ALPPRSLP 2404
Query: 345 PGPWKPIP------SVSPGPWKPTPSVSSASWKSSSV-----SPSSWKSPPASPESWKSG 393
P+ +P S S P P P +S+ ++ S V SP + PP+ P+S
Sbjct: 2405 SDPFSRVPASPQSQSSSQSPLTPRP-LSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPF 2463
Query: 394 PPELRKTAPTLSPEHWKAVPPVSPELRKPGPPLSPEIRSPAGSPELRKPSGSPDLWKLSP 453
P + P +KA L G P + PAG + PSG P + SP
Sbjct: 2464 APLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALP-AGPAGELHAKVPSGQPPNFVRSP 2522
Query: 454 DQ----RKTSPASLDFPESQKSSRGGSPDLWKSSFFIEPQKPVFPETRKPGPSGPSESPK 509
SP FP++ G P L KP P+ P P G +
Sbjct: 2523 GTGAFVGTPSPMRFTFPQAV-----GEPSL----------KPPVPQPGLPPPHGINSHFG 2567
Query: 510 AASDIWKP------VLSIDTEPRKPALFPEPAKTAPP--ASPEARKRALFPEPRKHALFP 561
+ KP V + + P L P T SP R ++ P P P
Sbjct: 2568 PGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSP-LRPPSVLPPPAPDGSLP 2626
Query: 562 ELPKSA 567
L A
Sbjct: 2627 YLSHGA 2632
Score = 61.6 bits (148), Expect = 3e-09
Identities = 100/388 (25%), Positives = 139/388 (35%), Gaps = 63/388 (16%)
Query: 105 PVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKPTPLTPLEPQKPGSVVS 164
P+ P P S P+ +P L L P P P PL+P+ + +
Sbjct: 893 PLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPII-----TAAA 947
Query: 165 PELQTPLPSPE-PSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQKPAPVSPESVKATLS 223
P +PL E P S PE P + P+ E+ P+SP +A +
Sbjct: 948 PPALSPLGELEYPFGAKGDSDPESPLAAPILET---------------PISPPP-EANCT 991
Query: 224 NPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPAASPESRKSARTTSPEPRKPSP 283
+P+P P + PPS SP P EP P SP + S P+ P
Sbjct: 992 DPEP-----VPPMILPPSPGSPVGPASPILMEPL--PPQCSPLLQHSL-----VPQNSPP 1039
Query: 284 SESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSV 343
S+ P P SP +SP G + S P PA +
Sbjct: 1040 SQCSPPALPLSVPSP--------LSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSAT 1091
Query: 344 SPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVSP-SSWKSPPASPESWK---SGPPELRK 399
SP P P+ +S P P++ S +P +P + PE + S EL+
Sbjct: 1092 SPLP-SPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKG 1150
Query: 400 TAPTLSPEHWKAVPP--VSPELRKPGPPLSP-----EIRSPAG--SPELRKPSGSPDLWK 450
+ L PE V P V PE ++ SP E R+P P L K ++
Sbjct: 1151 SPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLIKSDIVNEISN 1210
Query: 451 LSPDQRKTSPASLDFPESQKSSRGGSPD 478
LS AS FP S+ GSPD
Sbjct: 1211 LS-----QGDASASFPGSEPLL--GSPD 1231
Score = 57.0 bits (136), Expect = 7e-08
Identities = 109/434 (25%), Positives = 154/434 (35%), Gaps = 113/434 (26%)
Query: 156 PQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQKPAPVSP 215
P +PG++ SP P + + SP P + L P P P P SP
Sbjct: 2107 PPQPGALGSPP-------PAAAPTIFIGSPTTPAGLSTSADGFLKP---PAGSVPGPDSP 2156
Query: 216 ESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPAASPESRKSARTTS 275
+ L P+ P S +P+G +PA E R T+
Sbjct: 2157 GELFLKLP---------------------PQVPAQVPSQDPFGLAPAYPLEPRFP---TA 2192
Query: 276 PEPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWK 335
P P PS + P +P P + R A PG + PPG+PR S P P
Sbjct: 2193 PPTYPPYPSPTGAPAQP-PMLGASSRPGAG--QPGEFHTTPPGTPRHQPSTPDPFLKPRC 2249
Query: 336 PA------KPAPSVSPGPWKPIPSVSPGPW----------KPTPSVSSASWKSSSV---- 375
P+ +P V G P +SP P+ K SS S+ ++
Sbjct: 2250 PSLDNLAVPESPGVGGGKASE-PLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVD 2308
Query: 376 SPSS--------WKSP-----PASPESWKSGP--------PELRKTAPTLSPEHWKAVPP 414
SPSS K+P P +P + + P P+ A L+P PP
Sbjct: 2309 SPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPS-----PP 2363
Query: 415 VSPELRKPG--------PPLSPEIRSPAGSPELRKPSGSPDLWKLSPDQRKTSPASLDFP 466
P++ +PG PPL+P + P P S L D PAS P
Sbjct: 2364 SHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRS-----LPSDPFSRVPAS---P 2415
Query: 467 ESQKSSRGG-SPDLWKSSFFIEPQKPVFPETRKPGP-SGPSESPKAASDIWKPVLSIDTE 524
+SQ SS+ +P + F PV P + P P S P P++ P +
Sbjct: 2416 QSQSSSQSPLTPRPLSAEAFC--PSPVTPRFQSPDPYSRPPSRPQSRD----PFAPLHKP 2469
Query: 525 PRKPALFPEPAKTA 538
PR P+P + A
Sbjct: 2470 PR-----PQPPEVA 2478
Score = 48.5 bits (114), Expect = 2e-05
Identities = 77/324 (23%), Positives = 122/324 (37%), Gaps = 72/324 (22%)
Query: 120 NSAEPKSIPALSMETQKLGSVLSPESPKPTPLTPLEPQKPGSVVSPELQTPLPSPEPSKP 179
+S+E S+P L + SV + P L PQ+P L+ P+ +
Sbjct: 4123 SSSEASSVPHLLAQP----SVSLGDQPGSMTQNLLGPQQP------MLERPMQNN----- 4167
Query: 180 ASVSSPEPPKSVPVCESQKLAP-------------------VPSPEPQKPAPVSPESVKA 220
+ P+PPK PV +S + P +P+ + +P + ++A
Sbjct: 4168 ---TGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQA 4224
Query: 221 TLSNPKPQKQSHFPET---LGPPSASSPESPVLAASPEPWG-PSPAASPESRKSA--RTT 274
L + Q+ +T P + +SP +L P+ G P P P A R
Sbjct: 4225 LLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQ 4284
Query: 275 SPEPRKPSPSES--------PEPWKPFPAVSPEPRRPAPAVSPGS-------WKPGPPGS 319
P PR P+P + P P P+ EP+RP+ SP S P PG+
Sbjct: 4285 GP-PRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGT 4343
Query: 320 PRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASW-KSSSVSPS 378
P+P P+ P + + A ++ + S GPW P +++ + SS+ P
Sbjct: 4344 PKP--QGPTLEPPPGRVSPAAAQLA----DTLFSKGLGPWDPPDNLAETQKPEQSSLVPG 4397
Query: 379 SWKS------PPASPESWKSGPPE 396
P AS S K P E
Sbjct: 4398 HLDQVNGQVVPEASQLSIKQEPRE 4421
Score = 46.2 bits (108), Expect = 1e-04
Identities = 48/172 (27%), Positives = 66/172 (38%), Gaps = 10/172 (5%)
Query: 130 LSMETQKLGSVLSPESPKPTPLTPL--EPQKPGSVVSP-ELQTPLPSPEPSKPASVSSP- 185
LSM+ VL PESP P E + PG E ++P P+ K P
Sbjct: 4807 LSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPG 4866
Query: 186 ----EPPKSVPVCESQKLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPS 241
+ + + + AP P + VS V+ LS P P++ S P L P
Sbjct: 4867 YTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQ-LSAPPPEEPSPPPSPLAPSP 4925
Query: 242 ASSPESPVLAASPEPWGPSPAASP-ESRKSARTTSPEPRKPSPSESPEPWKP 292
AS P P++ EP P SP S + P+PR P E + P
Sbjct: 4926 ASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRPP 4977
Score = 45.8 bits (107), Expect = 2e-04
Identities = 124/558 (22%), Positives = 182/558 (32%), Gaps = 90/558 (16%)
Query: 128 PALSMETQKLGSVLSPESPKPTPLTP----LEPQKPGSVVSPELQTPLPSPEPSKPASVS 183
PA+S E + G P TP EP + +S + Q L P+P S
Sbjct: 4031 PAVSSEATE-GPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSL 4089
Query: 184 SPEPPKSVPVCESQKLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSAS 243
+PP +P + Q+++ + + + L + + S P L PS S
Sbjct: 4090 QLQPPLRLPGQQQQQVSLLHT---------AGGGSHGQLGSGSSSEASSVPHLLAQPSVS 4140
Query: 244 SPESPVLAASPEPWGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPEPRRP 303
+ P + + GP R T P+P KP P P + P +
Sbjct: 4141 LGDQPG-SMTQNLLGPQQPML--ERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQL 4197
Query: 304 APAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWK--- 360
+ K P + + + + + +V P P P +
Sbjct: 4198 RAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLL 4257
Query: 361 ---------PTPSVSSASWKSSSVSPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKA 411
P P + P + PP P PP T P L P H
Sbjct: 4258 GCQPQLGGFPGPQTGPLQELGAGPRP---QGPPRLP-----APPGALSTGPVLGPVH-PT 4308
Query: 412 VPPVSP-------ELRKPGPPLSPEIRSPAGSPELRKPSGSPDLWKLSPDQRKTSPASLD 464
PP SP +L P L E + P P KP G L P + SPA+
Sbjct: 4309 PPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGP----TLEPPPGRVSPAAAQ 4364
Query: 465 FPESQKSSRGGSPDLWKSSFFIEPQKPVFPETRKPGPSG--PSESPKAASDIWKPV--LS 520
++ S G D P ET+KP S P + + LS
Sbjct: 4365 LADTLFSKGLGPWD--------PPDN--LAETQKPEQSSLVPGHLDQVNGQVVPEASQLS 4414
Query: 521 IDTEPRKP--ALFPEPAKT----APPASPEARKRALFPEPRK---HALFPEL--PKSALF 569
I EPR+ AL + K P +P L PR H L +L K+
Sbjct: 4415 IKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQL 4474
Query: 570 SESQKAVEL-------------GDELQIDAIDDQKCDILVQEELLASPKKL--LEDTLFP 614
S + + L G E ++ K D ++ L PK++ D L
Sbjct: 4475 STGRGSEGLRAEINGHIDSKLAGLEQKLQGTPSNKEDAAARKPLTPKPKRVQKASDRLVS 4534
Query: 615 SSKKLKK-DNQESSDAEL 631
S KKL+K D +S+A L
Sbjct: 4535 SRKKLRKEDGVRASEALL 4552
Score = 42.4 bits (98), Expect = 0.002
Identities = 71/291 (24%), Positives = 94/291 (32%), Gaps = 26/291 (8%)
Query: 155 EPQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQK----P 210
EP P QTP + K + V P S P+ L P P + P
Sbjct: 2723 EPSSPAFEQLSRGQTPFAGTQ-DKSSLVGLPPSKLSGPI-----LGPGSFPSDDRLSRPP 2776
Query: 211 APVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPAASPESRKS 270
P +P S+ Q+ + P S P+ + W A + S +
Sbjct: 2777 PPATPSSMDVNSRQLVGGSQAFYQRAPYPGSL-----PLQQQQQQLWQQQQATAATSMRF 2831
Query: 271 ARTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSAS 330
A + P P P + P R P P G PGP G + + +
Sbjct: 2832 AMSAR-FPSTPGPELGRQALGS-PLAGISTRLPGP----GEPVPGPAGPAQFIELRHNVQ 2885
Query: 331 SGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPPASPESW 390
G P P P VS P + P S + P +PPA PE
Sbjct: 2886 KGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPE-GLRGLAVSGLPPQKPSAPPA-PELN 2943
Query: 391 KSGPPELRKTAPTLSPEHWKAV--PPVSPELRKPGPPLSPEIRSPAGSPEL 439
S P PTL P + V PP S EL +P P + P PEL
Sbjct: 2944 NSLHPTPHTKGPTL-PTGLELVNRPPSSTELGRPNPLALEAGKLPCEDPEL 2993
Score = 40.8 bits (94), Expect = 0.005
Identities = 61/233 (26%), Positives = 82/233 (35%), Gaps = 78/233 (33%)
Query: 95 PKNQLNKETDPVKSPPLPEHQKIPCNS--------AEPKSIPAL---------------- 130
P + + E P + PL +H +P NS A P S+P+
Sbjct: 1011 PASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAEL 1070
Query: 131 -SMETQKLGSVLSPESPKPTPLTPLEPQKPGSVVSP--ELQTPLPSPEPSKP-------- 179
MET+K V PE P LEP + SP +L P PSP P+
Sbjct: 1071 HEMETEK---VSEPECPA------LEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGED 1121
Query: 180 --------ASVSSPEPPKSVPVCESQKLAPVPSPEPQKPAPVSPESV----KATLSNPKP 227
A S PEP ++ S+ +P++ APV+P V K T P
Sbjct: 1122 TAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSP 1181
Query: 228 ---QKQSHFPETLGPP-------------------SASSPESPVLAASPEPWG 258
Q++ P PP SAS P S L SP+P G
Sbjct: 1182 CEEQEEPRAPVAPTPPTLIKSDIVNEISNLSQGDASASFPGSEPLLGSPDPEG 1234
Score = 40.4 bits (93), Expect = 0.007
Identities = 103/399 (25%), Positives = 141/399 (35%), Gaps = 58/399 (14%)
Query: 207 PQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASP-EPWGPSP---A 262
P P S K LSNP P S P T P S + V +P E G P A
Sbjct: 4601 PTGPDYYSQLLTKNNLSNP-PTPPSSLPPT---PPPSVQQKMVNGVTPSEELGEHPKDAA 4656
Query: 263 ASPESRKSARTTS-----------PEP--------RKPSPSESPEPWKPFPAVSPEPRRP 303
++ +S ++ R TS P P R S +S P PA SPE
Sbjct: 4657 SARDSERALRDTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESIL- 4715
Query: 304 APAVSPGSWKPGPP--GSPRPWKSNPSASSGPWKPAKPAPSVSPGP-WKPIPSVSPGPWK 360
G P P GS R W+ A S P P P S+ P KP ++
Sbjct: 4716 ------GEEAPRFPHLGSGR-WEQEDRALS-PVIPLIPRASIPVFPDTKPYGALGLEVPG 4767
Query: 361 PTPSVSSASWKSSSVSPSSWKSPPASPESWKSGPPELRKTAPTLS---PEHWKAVPPVSP 417
P + K S VS S A+ K+ + A LS P ++ + P SP
Sbjct: 4768 KLPVTTWEKGKGSEVSVMLTVSAAAA----KNLNGVMVAVAELLSMKIPNSYEVLFPESP 4823
Query: 418 ELRKPGPPLSPEIRSPAGSP---ELRKPSGSPDLWK----LSPDQRKTSPASLDFPESQK 470
R P E P G E + P PD K + P S + Q+
Sbjct: 4824 A-RAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQE 4882
Query: 471 SSRGGSPDLWKSSFFI---EPQKPVFPETRKPGPSGPSESPKAASDIWKPVLSIDTEPRK 527
S P ++ + + ++ P +P P +P AS +P++ + TEP
Sbjct: 4883 SPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLA 4942
Query: 528 PALFPEPAKTA-PPASPEARKRALFPEPRKHALFPELPK 565
P P A P S + RA PE + + P L K
Sbjct: 4943 EPPVPSPLPLASSPESARPKPRARPPEEGEDSRPPRLKK 4981
Score = 32.0 bits (71), Expect = 2.4
Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 11/87 (12%)
Query: 141 LSPESPKPTPLTPLEPQKPGSVVSPELQTPL-PSPEPSKPASVSSPEPPKSVPVCESQKL 199
L+PE + ++ L PQKP + +PEL L P+P P ++P
Sbjct: 2916 LAPEGLRGLAVSGLPPQKPSAPPAPELNNSLHPTPHTKGP----------TLPTGLELVN 2965
Query: 200 APVPSPEPQKPAPVSPESVKATLSNPK 226
P S E +P P++ E+ K +P+
Sbjct: 2966 RPPSSTELGRPNPLALEAGKLPCEDPE 2992
>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
Length = 1970
Score = 112 bits (281), Expect = 1e-24
Identities = 129/436 (29%), Positives = 179/436 (41%), Gaps = 52/436 (11%)
Query: 142 SPESP-KPTPLTPLEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLA 200
+P SP P P +P P PG +SP P+ EP P +P+ P P +
Sbjct: 1568 TPGSPGSPGPSSPYIPS-PGGAMSPSYSPTSPAYEPRSPGGY-TPQSPSYSPT------S 1619
Query: 201 PVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGP- 259
P SP +P SP N P S+ P + + SP SP + + + P
Sbjct: 1620 PSYSPTSPSYSPTSP--------NYSPTSPSYSPTS----PSYSPTSPSYSPTSPSYSPT 1667
Query: 260 SPAASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGS 319
SP+ SP S S TSP SPS SP SP +P+ SP S P S
Sbjct: 1668 SPSYSPTS-PSYSPTSPSYSPTSPSYSP--------TSPSYSPTSPSYSPTS----PSYS 1714
Query: 320 PRPWKSNPSASSGPWKPAKPAPSVSPGPWKPI-PSVSPGPWKPTPSVSSASWKSSSVSPS 378
P +P++ S + P P+ S + + P P+ SP TP+ S S S S SP+
Sbjct: 1715 PTSPSYSPTSPS--YSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPT 1772
Query: 379 SWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPELRKPGPPLSPEIRSPAGSPE 438
S P SP ++ P T+P+ SP + P SP P +P SP+ SP
Sbjct: 1773 SPNYTPTSP-NYSPTSPSYSPTSPSYSPTS-PSYSPSSPRYTPQSPTYTPS--SPSYSPS 1828
Query: 439 LRKPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGSPDLWKSSFFIEPQKPVF-PETR 497
PS SP K +P SP+S ++ + SP +S P P + P T
Sbjct: 1829 --SPSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTP 1886
Query: 498 KPGPSGPSESPKAASDIWKPVLSIDTEPRKPALFPEPAK---TAPPASPEARKRALFPEP 554
K P+ P+ SP S ++ P S P P P K T+P SP + K + + P
Sbjct: 1887 KYSPTSPTYSP--TSPVYTPT-SPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTY-SP 1942
Query: 555 RKHALFPELPKSALFS 570
P P +L S
Sbjct: 1943 TSPGYSPTSPTYSLTS 1958
Score = 95.1 bits (235), Expect = 2e-19
Identities = 113/397 (28%), Positives = 155/397 (39%), Gaps = 30/397 (7%)
Query: 166 ELQTPLPSPEPSKPASV---SSPEPPKSV-PVCESQKLAPVPSPEPQKPAPVSPESVKAT 221
E+ T +P + P + S+P P + P P+ P+ S + A
Sbjct: 1485 EIPTNIPGLGAAGPTGMFFGSAPSPMGGISPAMTPWNQGATPAYGAWSPSVGSGMTPGAA 1544
Query: 222 LSNPKPQKQ-SHFPETLGPPSASSPESPVLAASPEPWGPSPAASPESRKSARTTSPEPRK 280
+P S F P + +P SP P+ PSP + S + + EPR
Sbjct: 1545 GFSPSAASDASGFSPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRS 1604
Query: 281 P------SPSESPEPWKPFPAVSPEPRRPAPAVSP--GSWKPGPPGSPRPWKSNPSASSG 332
P SPS SP + SP +P SP S+ P P S P + S +S
Sbjct: 1605 PGGYTPQSPSYSPTS-PSYSPTSPSYSPTSPNYSPTSPSYSPTSP-SYSPTSPSYSPTSP 1662
Query: 333 PWKPAKPAPSVSPGPWKPI-PSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPPASPESWK 391
+ P P+ S + + P PS SP +P+ S S S S SP+S P SP S+
Sbjct: 1663 SYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSP-SYS 1721
Query: 392 SGPPELRKTAPTLSPEHWKAVPPVSPELRKPGPPLSPEIRSPAGSPELRKPSGSPDLWKL 451
P T+P+ SP + P SP P +P SP+ SP PS SP
Sbjct: 1722 PTSPSYSPTSPSYSPTS-PSYSPTSPNYSPTSPNYTP--TSPSYSP--TSPSYSPTSPNY 1776
Query: 452 SPDQRKTSPASLDFPESQKSSRGGSPDLWKSSFFIEPQKPVF-PETRKPGPSGPSESPKA 510
+P SP S + + S SP SS PQ P + P + PS PS SP
Sbjct: 1777 TPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSP-- 1834
Query: 511 ASDIWKPVLSIDTEPRKPALFPEPAKTAPPASPEARK 547
S + P T P PE T+P SP + K
Sbjct: 1835 TSPKYTP-----TSPSYSPSSPEYTPTSPKYSPTSPK 1866
Score = 38.1 bits (87), Expect = 0.033
Identities = 41/138 (29%), Positives = 56/138 (40%), Gaps = 11/138 (7%)
Query: 79 YHITSKHASPDKWNDKPKNQLNKETDPVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLG 138
Y +S SP + P + T P SP PE+ P + + P S + K
Sbjct: 1818 YTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYT--PTSPKYSPTSPKYSPTSPKY- 1874
Query: 139 SVLSPESPKPTPLTP-LEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQ 197
SP SP +P TP P P + + TP SP+ S + SP PK P S
Sbjct: 1875 ---SPTSPTYSPTTPKYSPTSPTYSPTSPVYTPT-SPKYSPTSPTYSPTSPKYSPT--SP 1928
Query: 198 KLAPVPSPEPQKPAPVSP 215
+P SP+ +P SP
Sbjct: 1929 TYSPT-SPKGSTYSPTSP 1945
Score = 30.8 bits (68), Expect = 5.3
Identities = 30/110 (27%), Positives = 44/110 (40%), Gaps = 8/110 (7%)
Query: 70 TSKMYS--NVYYHITSKHASPDKWNDKPKNQLNKETDPVKSPPLPEHQKIPCNSAEPKSI 127
TS YS + Y TS SP P + T PV +P P++ P + +
Sbjct: 1863 TSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYS--PTSPTYSPTS 1920
Query: 128 PALSMETQKLGSVLSPESPKPTPLTPLEPQKPGSVVSPELQTPLPSPEPS 177
P S + SP SPK + +P P + + L +P SP+ S
Sbjct: 1921 PKYSPTSP----TYSPTSPKGSTYSPTSPGYSPTSPTYSLTSPAISPDDS 1966
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 110 bits (274), Expect = 7e-24
Identities = 136/506 (26%), Positives = 197/506 (38%), Gaps = 97/506 (19%)
Query: 93 DKPKN-----QLNKETDPVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPK 147
+KPK +++++ P K PP K+ P +P + + V PE P+
Sbjct: 10434 EKPKAPPKGPEISEKIIPPKKPPT----KVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPR 10489
Query: 148 PTPLTPLEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSP-E 206
P E P VV PE + P+P P+K P+ P++ +K PVP P +
Sbjct: 10490 VPPTKVPEVLPPKEVV-PEKKVPVP---PAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKK 10545
Query: 207 PQKPAPVSPESVKATLSNPK------PQKQSHFPETLGPPSASSPESPVLAASPEPWGPS 260
P+ P PE KA + K P+ +S PE P PE V AA P+ +
Sbjct: 10546 PEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVT 10605
Query: 261 PAASPESRKSA----RTTSPEPRKPS--PSESPE------PWKPFP-AVSPEPRRPAPAV 307
P PE+ K + P P+KP P++ PE P K P A+ P+P P P V
Sbjct: 10606 PVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEV 10665
Query: 308 SPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSS 367
+ P P +PA P P V+ P KP+P K P+V
Sbjct: 10666 FEEPEEVALEEPPAEVVEEP-------EPAAP-PQVTVPPKKPVPE------KKAPAV-- 10709
Query: 368 ASWKSSSVSPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPEL-------R 420
V+ P PE K PE K P + P+ +A P PE+ +
Sbjct: 10710 -------VAKKPELPPVKVPEVPKEVVPE--KKVPLVVPKKPEAPPAKVPEVPKEVVPEK 10760
Query: 421 KPGPPLSPEIRSPAGSPELRKPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGSPDLW 480
K P PE+ PA PE+ K + + +R SP P+++
Sbjct: 10761 KVAVPKKPEV-PPAKVPEVPKKPVLEEKPAVPVPERAESP---------------PPEVY 10804
Query: 481 KSSFFIEPQKPVFPETRKPGPSGPSESPKAASDIWKPVLSIDTEPRKPALFPE---PAKT 537
+ I P++ + PE KP P E P+ P ++ EP+K + PE P
Sbjct: 10805 EEPEEIAPEEEIAPEEEKPVPVAEEEEPEV------PPPAVPEEPKK--IIPEKKVPVIK 10856
Query: 538 APPASPEARKRALFPEPRKHALFPEL 563
P A P PEP K P+L
Sbjct: 10857 KPEAPPPKE-----PEPEKVIEKPKL 10877
Score = 102 bits (254), Expect = 1e-21
Identities = 134/530 (25%), Positives = 187/530 (35%), Gaps = 79/530 (14%)
Query: 86 ASPDKWNDKPKNQLNKETDPVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPES 145
A P K + PK E P K P+P +K + +P ++ +K+ + P+
Sbjct: 10520 APPPKVPEAPK-----EVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKP 10574
Query: 146 PKPTPLTPLEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSP 205
P P P P++ V PE + P P+ + V PE PK V +K PVP P
Sbjct: 10575 ESPPPEVPEAPKE----VVPEKKVPAAPPKKPEVTPVKVPEAPKEV---VPEKKVPVPPP 10627
Query: 206 -EPQKPAPVSPESVKATLSNPK------PQKQSHFPETLGPPSASSPESPVLAASPEPWG 258
+P+ P PE K + K P+ +S PE P + E P E
Sbjct: 10628 KKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEE--- 10684
Query: 259 PSPAASPESRKSARTTSPEPRKPS---------PSESPE------PWKPFPAVSPEPRRP 303
P PAA P+ + PE + P+ P + PE P K P V P+
Sbjct: 10685 PEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEA 10744
Query: 304 APAVSP-------GSWKPGPPGSPR-PWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVS 355
PA P K P P P P P KPA V P P V
Sbjct: 10745 PPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVY 10804
Query: 356 PGPWKPTPSVSSASWKSSSVSPSSWKS----PPASPESWKSGPPELRKTAPTLSPEHWKA 411
P + P A + V + + PPA PE K PE +K PE A
Sbjct: 10805 EEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPE-KKVPVIKKPE---A 10860
Query: 412 VPPVSPELRK--PGPPLSPEIRSPAGSPELRKPSGSPDLWKLSPDQRKTSPASLDFPESQ 469
PP PE K P L P R P P K +++L +K P PE
Sbjct: 10861 PPPKEPEPEKVIEKPKLKP--RPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKV 10918
Query: 470 KSSRGGSPDLWKSSFFIEPQKPVFPE---------TRKPGPSGPSESPKAASDIWKPV-- 518
+ + P K + P++ P+ ++P P PK + KP
Sbjct: 10919 ELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVP 10978
Query: 519 ----------LSIDTEPRKPALFPEPAKTAPPASPEARKRALFPEPRKHA 558
+ + T ++ PEP K P P A P+P+ A
Sbjct: 10979 EPPPPKPVEEVEVPTVTKRERKIPEPTK-VPEIKPAIPLPAPEPKPKPEA 11027
Score = 100 bits (248), Expect = 7e-21
Identities = 141/506 (27%), Positives = 194/506 (38%), Gaps = 63/506 (12%)
Query: 101 KETDPVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKPTPLTPLEPQKPG 160
KE P K P+P +K + +P +++ +K+ + P+ P P EP++
Sbjct: 10614 KEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVA 10673
Query: 161 SVVSPELQTPLPSPEPSKPASVSSPEPPKSVP-------VCESQKLAPVPSPE------P 207
P + PEP+ P V+ P P K VP V + +L PV PE P
Sbjct: 10674 LEEPP--AEVVEEPEPAAPPQVTVP-PKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVP 10730
Query: 208 QKPAPV----SPESVKATLSN-PK---PQKQSHFPETLGPPSASSPE---SPVLAASPEP 256
+K P+ PE+ A + PK P+K+ P+ P A PE PVL P
Sbjct: 10731 EKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAV 10790
Query: 257 WGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKPFP-AVSPEPRRPAPAVSPGSWKPG 315
P A SP PE P +PE KP P A EP P PAV P
Sbjct: 10791 PVPERAESPPPEV---YEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAV------PE 10841
Query: 316 PPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPI--PSVSPGPWKPTPSVSSASWKSS 373
P P K P KP P P P P K I P + P P P P+ K
Sbjct: 10842 EPKKIIPEKKVPVIK----KPEAPPPK-EPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEK 10896
Query: 374 SVSPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPELRKPGPPLSPEIRSP 433
K+ P K PE + P P K V + PE RKP P ++S
Sbjct: 10897 IF---QLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPE-RKPEPKEEVVLKSV 10952
Query: 434 AGS-PELRKPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGSPDLWKSSFFIEPQKPV 492
PE +P P KL ++ PA + P + P + K I P+
Sbjct: 10953 LRKRPEEEEPKVEPK--KL---EKVKKPAVPEPPPPKPVEEVEVPTVTKRERKI-PEPTK 11006
Query: 493 FPETRKPGPSGPSESPKAASDIWKPVLSIDTEPRKPALFPEPAKTAPPAS-PEARKRALF 551
PE KP P+ PK KP + T + P + PEP A P + P K+A
Sbjct: 11007 VPEI-KPAIPLPAPEPKP-----KPEAEVKT-IKPPPVEPEPTPIAAPVTVPVVGKKAEA 11059
Query: 552 PEPRKHALFPELPKSALFSESQKAVE 577
P++ A P+ P + ++ +E
Sbjct: 11060 KAPKEEAAKPKGPIKGVPKKTPSPIE 11085
Score = 82.4 bits (202), Expect = 2e-15
Identities = 126/540 (23%), Positives = 195/540 (36%), Gaps = 73/540 (13%)
Query: 143 PESPKPT-PLTPLEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSV----PVCESQ 197
PE P PT P P P K PE + P+P P+ KP PE PK V
Sbjct: 9799 PEEPVPTKPKAP--PAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISIT 9856
Query: 198 KLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQ-------SHFPETLGPPSASSPESPV- 249
K EP P+ P+ V A P P+K+ P+ L P + E V
Sbjct: 9857 KREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEEVAFEEEVVT 9916
Query: 250 -----LAASPEPW-----------GPSPAASPESRKSARTTSPEPRK--PSPSESPEPWK 291
L E + P + + R PE +K P P + P
Sbjct: 9917 HVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPA 9976
Query: 292 PFPAVSPEPRRPAPAVSPGSWKPGPPGSPR-PWKSNPSASSGPWKPAKPAPSVSPGPWKP 350
P V +P P + P KP P P P K P K P P P
Sbjct: 9977 KVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEE-----KVPVPVPKKVEAPPAK 10031
Query: 351 IPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPPAS-PESWKSGPPELRKTAPTLSPEHW 409
+P V P KP P K +P ++PPA PE K PE +K PT P+
Sbjct: 10032 VPEV---PKKPVPEK-----KVPVPAPKKVEAPPAKVPEVPKKLIPEEKK--PTPVPKKV 10081
Query: 410 KAVPPVSPELRKPGP-----PLSPEIR-----SPAGSPELRKPSGSPDLWKLSPDQRKTS 459
+A PP P+ R+P P P E+ P + P+ ++ P++ +
Sbjct: 10082 EAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVL 10141
Query: 460 PASLDFPESQKSSRGGSPDLWKSSFFIEPQKPVFPETRKPGPSGPSESPKAASDIWKPVL 519
P + P ++ + + F+ P++ V PE KP P+ P+ + + +
Sbjct: 10142 PEEEEIPPEEEEVPPEEEYVPEEEEFV-PEEEVLPEV-KPKVPVPAPVPEIKKKVTEKKV 10199
Query: 520 SIDTEPRKPALFPEPAKTAPPASPEARKRALFPEPRKHALFP----ELPKSALFSESQKA 575
I + P PAK KR + P++ + P E P+ SE +
Sbjct: 10200 VIPKKEEAP-----PAKVPEVPKKVEEKRIIL--PKEEEVLPVEVTEEPEEEPISEEEIP 10252
Query: 576 VELGDELQIDAIDDQKCDILVQEELLASPKKLLEDTLFPSSKKLKKDNQESSDAELSSSE 635
E +++ + + ++++ + +P + + P +K KK +E + E
Sbjct: 10253 EEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKE 10312
Score = 79.3 bits (194), Expect = 1e-14
Identities = 95/380 (25%), Positives = 146/380 (38%), Gaps = 46/380 (12%)
Query: 98 QLNKETDPVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKPTPLTPLEPQ 157
++ KE P K +P+ ++P A+ +P + +K + + P P EP+
Sbjct: 10751 EVPKEVVPEKKVAVPKKPEVP--PAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPE 10808
Query: 158 K--PGSVVSPELQTPLP-----SPEPSKPASVSSPE---PPKSVPVCESQKLAPVPSPEP 207
+ P ++PE + P+P PE PA P+ P K VPV + + P PEP
Sbjct: 10809 EIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEP 10868
Query: 208 QK---PAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPAAS 264
+K + P + PK + + P PE P + PE +P
Sbjct: 10869 EKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQV---PEKVELTPLKV 10925
Query: 265 PESRKSARTTSPEPRKPSPSES----------PEPWKPFPAVSPEPRRPAPAVSPGSWKP 314
P K R PE RKP P E PE +P EP++ P +P
Sbjct: 10926 PGGEKKVRKLLPE-RKPEPKEEVVLKSVLRKRPEEEEP----KVEPKKLEKVKKPAVPEP 10980
Query: 315 GPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSS 374
PP P P+ + K +P P P+P+ P KP P + K
Sbjct: 10981 -PPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEP---KPKPEAEVKTIKPPP 11036
Query: 375 VSPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVP--PVSPELRKPGPPLSPEIRS 432
V P +P A+P + P + K A +P+ A P P+ +K P+ E R
Sbjct: 11037 VEPE--PTPIAAPVT----VPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRK 11090
Query: 433 -PAGSPELRKPSGSPDLWKL 451
GS + P +P ++L
Sbjct: 11091 LRPGSGGEKPPDEAPFTYQL 11110
Score = 72.8 bits (177), Expect = 1e-12
Identities = 146/670 (21%), Positives = 249/670 (37%), Gaps = 78/670 (11%)
Query: 80 HITSKH--ASPDKWNDKPKNQL---NKETDPVKSPPLPEHQKIPCNSAEPKSIPALSMET 134
HI SK A P + ++ + ++ K ++ PP + + P K +PA +
Sbjct: 9541 HIISKRVEAEPAEVTERQEKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKK 9600
Query: 135 QKLGSVLSPESP-KPTPLTPLEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPV 193
+K+ PE P KP P E + P V+ +++ PLP+ + ++ E V V
Sbjct: 9601 EKVPPPKVPEEPKKPVP----EKKVPPKVI--KMEEPLPAKVTERHMQITQEE---KVLV 9651
Query: 194 CESQKLAPVPSPEPQKPAPVSPE----SVKATLSNPKPQKQSHFPETLGPPSASSPESPV 249
++K AP + P++P PE +K P K + F + + S E+P
Sbjct: 9652 AVTKKEAPPKARVPEEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAP- 9710
Query: 250 LAASPEPWGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSP 309
EP E ++ A T E E E ++ + E P
Sbjct: 9711 ---KREPQPIKEVTIMEEKERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTE---- 9763
Query: 310 GSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSAS 369
+ R ++ +P KP P V P P +P+P+ P +
Sbjct: 9764 -EYDQYEEYEEREYERYEEHEEYITEPEKPIP-VKPVPEEPVPTKPKAPPAKVLKKAVPE 9821
Query: 370 WKSSSVSPSSWKSPPAS-PESWKSGPPELRKTAPTLSPEHWKAVPPVSPELRKPGPPLSP 428
K P K PP PE K E + + T E + P + KP ++
Sbjct: 9822 EKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISIT-KREKEQVTEPAAKVPMKPKRVVAE 9880
Query: 429 EIRSPAGSPELRKPSGSPDLWK-LSPDQRKTSPASLDFPESQKSSRGGSPDLWKSSFFIE 487
E + P E+ P P++ K L P++ + E + F E
Sbjct: 9881 E-KVPVPRKEVAPPVRVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITE 9939
Query: 488 --------------PQKPVFPETRKPGPSGPSESPKAASDIWKPVLSIDTEPRKPALFPE 533
P+KPV PE +KP P K A P + E + P L P+
Sbjct: 9940 EEVVPVIPVKVPEVPRKPV-PEEKKP---VPVPKKKEAPPAKVPEVPKKPEEKVPVLIPK 9995
Query: 534 PAKTAPPASPEARKRAL------FPEPRK----HALFPELPKSALFSE-----SQKAVEL 578
K P PE K+ + P P+K A PE+PK + + + K VE
Sbjct: 9996 KEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEA 10055
Query: 579 G----DELQIDAIDDQKCDILVQEELLASPKKL-LEDTLFPSSKKLKKDNQESSDAELSS 633
E+ I ++K V +++ A P K+ + P L ++ + + E+
Sbjct: 10056 PPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVP 10115
Query: 634 SEYIKTDLDAMDIKGQESSSDQEQVDVESIDFSKENKMDMTSPEQSRNVLQFTEEKEAFI 693
E + + + + + +E ++E+V E + E + PE+ ++ E+E F+
Sbjct: 10116 EEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEE--EEVPPEE-----EYVPEEEEFV 10168
Query: 694 SEEEIAKYMK 703
EEE+ +K
Sbjct: 10169 PEEEVLPEVK 10178
Score = 60.8 bits (146), Expect = 5e-09
Identities = 124/587 (21%), Positives = 207/587 (35%), Gaps = 134/587 (22%)
Query: 123 EPKSIPALSMETQKLGSVLSPESPKPTPLTPLEPQKPGSVVS----PELQTPLPSPEPSK 178
E + +P + ++ ++ PE KP P+ + P V PE + P+ P+ K
Sbjct: 9939 EEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEK 9998
Query: 179 PASVSSPE------PPKSVPVCESQKLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSH 232
P PE P + VPV PVP PA V
Sbjct: 9999 PPPAKVPEVPKKPVPEEKVPV-------PVPKKVEAPPAKV------------------- 10032
Query: 233 FPETLGPPSASSPESPVLAASPEPWGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKP 292
PE P PE V +P+ PA PE K PE +KP+P P+ +
Sbjct: 10033 -PEV---PKKPVPEKKVPVPAPKKVEAPPAKVPEVPKK---LIPEEKKPTP--VPKKVEA 10083
Query: 293 FPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIP 352
P P+ R P P P + + P
Sbjct: 10084 PPPKVPKKREPVPV--------------------------PVALPQEEEVLFEEEIVPEE 10117
Query: 353 SVSPGPWKPTPSVSSASWKSSSVSPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAV 412
V P + P + V P + PP E PPE PE + V
Sbjct: 10118 EVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEV----PPE-----EEYVPEEEEFV 10168
Query: 413 PPVSPELRKPGPPLSPEIRSPAGSPELRKPSGSPDLWKLSPDQRKTSPASLDFPESQKSS 472
P + P + P++ PA PE++K K + + P+ +++
Sbjct: 10169 PE-----EEVLPEVKPKVPVPAPVPEIKK---------------KVTEKKVVIPKKEEAP 10208
Query: 473 RGGSPDLWKSSFFIEPQKPVFPETRKPGPSGPSESPKAASDIWKPVLSIDTEPRKPALFP 532
P++ K +E ++ + P+ + P +E P+ + +S + P +P
Sbjct: 10209 PAKVPEVPKK---VEEKRIILPKEEEVLPVEVTEEPE------EEPISEEEIPEEPPSIE 10259
Query: 533 EPAKTAPPASPEARKRALFPEPRKHALFPELPKSALFSESQKAVELGDELQIDAIDDQKC 592
E + APP PE K+A+ PE P + K VE I ++K
Sbjct: 10260 EVEEVAPPRVPEVIKKAV----------PEAP-----TPVPKKVEAPPAKVSKKIPEEKV 10304
Query: 593 DILVQEELLASPKKLLEDTLFPSSKKLKKDNQESSDAELSSSEYIKTDL-DAMDIKGQES 651
+ VQ++ A P K+ E KK+ +E+ +T L + + + ++
Sbjct: 10305 PVPVQKK-EAPPAKVPEVPKKVPEKKVLVPKKEAVPPAKG-----RTVLEEKVSVAFRQE 10358
Query: 652 SSDQEQVDVESIDFSKENKMDMTSPEQSRNVLQFTEEKEAFISEEEI 698
+E++++E ++ E ++ E+ V ++ EE E EE I
Sbjct: 10359 VVVKERLELEVVEAEVE---EIPEEEEFHEVEEYFEEGEFHEVEEFI 10402
Score = 54.7 bits (130), Expect = 3e-07
Identities = 156/688 (22%), Positives = 242/688 (35%), Gaps = 127/688 (18%)
Query: 82 TSKHASPDKWNDKPKNQLNKETDPVKSPPLPEHQ-----KIPCNSAEPKSIPALSM---- 132
TS+ +K +++K+ P K P + K+P + I M
Sbjct: 9192 TSRRMEEEKVQVTKVPEVSKKIVPQKPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFAS 9251
Query: 133 ETQKLGSVLSPESPKPTPLTPLEPQKPGSVVSPELQTPLPSPE-PSKPASVSSPEPPKSV 191
T++ SV PE K + +K +S ++ P PE P KPA P +
Sbjct: 9252 HTEEEVSVTVPEVQKEI----VTEEKIHVAISKRVEPPPKVPELPEKPA------PEEVA 9301
Query: 192 PVCESQKLAP----------VPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPS 241
PV +K+ P P PE +KP PV + A P+ K+ E + P
Sbjct: 9302 PVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPV 9361
Query: 242 ASSPESPVLAASPEPWGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKP-FPAVS-PE 299
A E+P PA PE +K T ESP P P P PE
Sbjct: 9362 AKKKEAP------------PAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPE 9409
Query: 300 PRRPAP----AVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVS 355
R+P P V P P P P P + K A P P P P VS
Sbjct: 9410 ERKPVPRKEEEVPPPPKVPALPKKPVPEE----------KVAVPVPVAKKAP-PPRAEVS 9458
Query: 356 --------------------PGPWKPTPSVSSA--SWKSSSVSPSSWKSPPASPESWKSG 393
P + T SA W S S E +
Sbjct: 9459 KKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEE 9518
Query: 394 PPELRKTAPTLSPEHW-------------KAVPPVSPELRKPGPPLSPEIRSPAGSPELR 440
E+ + PE + +A P E ++ L P+I + P
Sbjct: 9519 EAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEKKIVLKPKIPAKIEEPPPA 9578
Query: 441 KPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGSPDLWKSSFFIEPQKPVFPETRKPG 500
K +P K+ P+++ +P P+ +K P+ EP+KPV PE + P
Sbjct: 9579 KVPEAPK--KIVPEKKVPAPV----PKKEKVPPPKVPE--------EPKKPV-PEKKVPP 9623
Query: 501 PSGPSESPKAASDIWKPVLSIDTEPRKPALFPEPAKTAPPAS--PEARKRALFPEPRKHA 558
E P A + + + I E + L K APP + PE KRA+ PE +
Sbjct: 9624 KVIKMEEPLPAK-VTERHMQITQEEK--VLVAVTKKEAPPKARVPEEPKRAV-PEEKVLK 9679
Query: 559 LFP--ELPKSALFSESQKAVELGDELQIDAIDDQKCDILVQEELLASPKKLLEDTLFPSS 616
L P E A +E +K V +++ I+A + I +E+ +K TL +
Sbjct: 9680 LKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPI---KEVTIMEEKERAYTLEEEA 9736
Query: 617 KKLKKDNQESSDAELSSSEYIKTDLDAMDIKGQESSSDQEQVDVESIDFSKENKMDMTSP 676
++++ + E E+ + + E E+ + + +E++ +T P
Sbjct: 9737 VSVQREEEYEEYEEYDYKEF-------EEYEPTEEYDQYEEYEEREYERYEEHEEYITEP 9789
Query: 677 EQSRNVLQFTEEKEAFISEEEIAKYMKR 704
E+ V EE + AK +K+
Sbjct: 9790 EKPIPVKPVPEEPVPTKPKAPPAKVLKK 9817
Score = 49.3 bits (116), Expect = 1e-05
Identities = 52/209 (24%), Positives = 76/209 (36%), Gaps = 33/209 (15%)
Query: 93 DKPKNQLNKETDPVKSPP--------LPEHQKIPCNSAEPKSI-------PALSMETQKL 137
+KP+ E P+K P LPE + P KS+ +E +KL
Sbjct: 10910 EKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKL 10969
Query: 138 GSVLSPESPKPTPLTPLEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEP-PKSVPVCES 196
V P P+P P P+E + +V E + P P+ P ++ P P PK P E
Sbjct: 10970 EKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEV 11029
Query: 197 QKLAPVP-SPEP---QKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAA 252
+ + P P PEP P V KA PK + A+ P+ P+
Sbjct: 11030 KTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEE-------------AAKPKGPIKGV 11076
Query: 253 SPEPWGPSPAASPESRKSARTTSPEPRKP 281
+ P A + R + P P
Sbjct: 11077 PKKTPSPIEAERRKLRPGSGGEKPPDEAP 11105
Score = 47.0 bits (110), Expect = 7e-05
Identities = 106/502 (21%), Positives = 168/502 (33%), Gaps = 52/502 (10%)
Query: 86 ASPDKWNDKPKNQLNKETDPVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPES 145
A P K + PK + P K P+P +K+ A P +P + + L PE
Sbjct: 10027 APPAKVPEVPKKPV-----PEKKVPVPAPKKV---EAPPAKVPEVPKK-------LIPEE 10071
Query: 146 PKPTPLTPLEPQKPGSVVSPELQTPLPSPEPSKPASVSSPE-PPKSVPVCESQKLAPVPS 204
KPTP+ P V P+P P + + E P+ + E +++ P
Sbjct: 10072 KKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEE 10131
Query: 205 PEPQKPAPVSPESVKATLSNPK-PQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPAA 263
+ V PE + + P ++ + PE PE VL +P P PA
Sbjct: 10132 EVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPE----EEEFVPEEEVL-PEVKPKVPVPAP 10186
Query: 264 SPESRKSA---RTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPAP---AVSPGSWKPGPP 317
PE +K + P+ + P++ PE P E R P V P P
Sbjct: 10187 VPEIKKKVTEKKVVIPKKEEAPPAKVPE----VPKKVEEKRIILPKEEEVLPVEVTEEPE 10242
Query: 318 GSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVSP 377
P + P + + AP P P P PTP + VS
Sbjct: 10243 EEPISEEEIPEEPPSIEEVEEVAP-----PRVPEVIKKAVPEAPTPVPKKVEAPPAKVSK 10297
Query: 378 SSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPELRKPGPPLSPEIRSPAGSP 437
+ P K PP P PE VP G + E S A
Sbjct: 10298 KIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVPPAKGRTVLEEKVSVAFRQ 10357
Query: 438 ELRKPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGSPDLWKSSFFIEPQKPVFPETR 497
E+ + K + + PE ++ + ++ F E ++ + E
Sbjct: 10358 EV--------VVKERLELEVVEAEVEEIPEEEEFHE--VEEYFEEGEFHEVEEFIKLEQH 10407
Query: 498 KPGPSGPSESPKAASDIWK-PVLSIDTEPRKPALFPE-PAKTAPPASPEARKRALFPEPR 555
+ E ++++ + + +P+ P PE K PP P + + P
Sbjct: 10408 RVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKIIPPKKPPTK---VVPRKE 10464
Query: 556 KHALFPELPKSALFSESQKAVE 577
A PE+PK + E + E
Sbjct: 10465 PPAKVPEVPKKIVVEEKVRVPE 10486
Score = 34.3 bits (77), Expect = 0.48
Identities = 25/64 (39%), Positives = 29/64 (45%), Gaps = 7/64 (10%)
Query: 177 SKPASVSSPEPP-KSVPVCESQKLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPE 235
+ P V SPEP KS +S K V SPEP P VSP K T +K H P
Sbjct: 32661 TSPPRVKSPEPRVKSPEAVKSPKR--VKSPEPSHPKAVSPTETKPT----PTEKVQHLPV 32714
Query: 236 TLGP 239
+ P
Sbjct: 32715 SAPP 32718
Score = 33.5 bits (75), Expect = 0.81
Identities = 36/131 (27%), Positives = 57/131 (43%), Gaps = 25/131 (19%)
Query: 123 EPKSIPALSMETQKLGSVLSPES------PKPT-PLTPLEPQKPGSVVSPELQTPLPSPE 175
E +S L + T+++ L P P PT P+ + P++ VV+P + LP+PE
Sbjct: 8914 EARSTAELYLTTKEIKLELKPPDIPDSRVPIPTMPIRAVPPEEIPPVVAPPIPLLLPTPE 8973
Query: 176 PSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPE 235
KP PPK + V + + + KP ++P + + P P P
Sbjct: 8974 EKKP-------PPKRIEVTK-KAVKKDAKKVVAKPKEMTPR--EEIVKKPPP------PT 9017
Query: 236 TLGPPSASSPE 246
TL P A +PE
Sbjct: 9018 TLIP--AKAPE 9026
Score = 33.5 bits (75), Expect = 0.81
Identities = 40/173 (23%), Positives = 66/173 (38%), Gaps = 33/173 (19%)
Query: 401 APTLSPE-HWKAVPPVSPELRKPGPPLSPEIRSPAGSPELRKPSGSPDLWKLSPDQRKTS 459
AP PE K +PP +KP + P PA PE+ K + ++ P++ +
Sbjct: 10438 APPKGPEISEKIIPP-----KKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRV-PEEPRVP 10491
Query: 460 PASLDFPESQKSSRGGSPDLWKSSFFIEPQKPVFPETRKPGPSG------PSESPKAASD 513
P + PE + P K V PE + P P P + P+A +
Sbjct: 10492 PTKV--PE------------------VLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKE 10531
Query: 514 IWKPVLSIDTEPRKPALFPEPAKTAPPASPEARKRALFPEPRKHALFPELPKS 566
+ P+KP + P P A+ +K P+ + PE+P++
Sbjct: 10532 VVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEA 10584
Score = 33.1 bits (74), Expect = 1.1
Identities = 21/45 (46%), Positives = 22/45 (48%), Gaps = 4/45 (8%)
Query: 272 RTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGP 316
R SPEPR SP P + SPEP P AVSP KP P
Sbjct: 32665 RVKSPEPRVKSPEAVKSPKR---VKSPEPSHP-KAVSPTETKPTP 32705
Score = 30.8 bits (68), Expect = 5.3
Identities = 14/38 (36%), Positives = 20/38 (52%)
Query: 297 SPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPW 334
+P P P +KPGPPG+PR ++ S+ S W
Sbjct: 21739 APSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAW 21776
Score = 30.0 bits (66), Expect = 9.0
Identities = 36/144 (25%), Positives = 55/144 (38%), Gaps = 21/144 (14%)
Query: 248 PVLAASPEPWGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPAPAV 307
P + P+ P+P + + AR SP P + SPS P + A +P P R +V
Sbjct: 255 PRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIRHSPS----PVRHVRAPTPSPVR---SV 307
Query: 308 SPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSS 367
SP + P S S A +V+ GP P PWK V+S
Sbjct: 308 SPAARISTSP--------IRSVRSPLLMRKTQASTVATGP------EVPPPWKQEGYVAS 353
Query: 368 ASWKSSSVSPSSWKSPPASPESWK 391
+S + + + + E W+
Sbjct: 354 SSEAEMRETTLTTSTQIRTEERWE 377
Score = 30.0 bits (66), Expect = 9.0
Identities = 29/111 (26%), Positives = 44/111 (39%), Gaps = 24/111 (21%)
Query: 198 KLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPW 257
+L P P+ + P P P ++A PE + P A P P+L +PE
Sbjct: 8931 ELKPPDIPDSRVPIPTMP--IRAVP-----------PEEIPPVVA--PPIPLLLPTPEEK 8975
Query: 258 GPSP----AASPESRKSARTTSPEPRKPSPSES-----PEPWKPFPAVSPE 299
P P +K A+ +P++ +P E P P PA +PE
Sbjct: 8976 KPPPKRIEVTKKAVKKDAKKVVAKPKEMTPREEIVKKPPPPTTLIPAKAPE 9026
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 107 bits (267), Expect = 4e-23
Identities = 160/610 (26%), Positives = 229/610 (37%), Gaps = 124/610 (20%)
Query: 105 PVKSPPLPEHQKIPCNSAEP-----KSIPALSMETQKLGSVLSPESPK------------ 147
P PPLP SA P +I L +Q G++ P +P
Sbjct: 643 PPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQIL 702
Query: 148 -------PTPLTPLEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCE--SQK 198
P P P P PGS ++ P PS P S+P PP + + +Q
Sbjct: 703 VPPNGVVPPPPPPPPPPTPGSAMAQLKPAPC---APSLP-QFSAPPPPLKIHQVQHITQV 758
Query: 199 LAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVL--AASPEP 256
P P P P PAP+ P+ + PKP T+ P+++ +PV+ AA P P
Sbjct: 759 APPTPPPPPPIPAPLPPQ------APPKPL------VTIPAPTSTKTVAPVVTQAAPPTP 806
Query: 257 WGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKP-----FPAVSPEPRRPAPAV--SP 309
P P A + A P P P P P P P P P P P+V
Sbjct: 807 TPPVPPAKKQPAFPASYIPPSPPTP-PVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQI 865
Query: 310 GSWKPGPPGSP-------RPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGP-WKP 361
S P PP P +P +N + S P AKP W+P P P + P
Sbjct: 866 ASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKP-------KWQPSSIPVPSPDFPP 918
Query: 362 TPSVSSASWKSSSVSPSSWKSPP----ASPESWKSGPPELRKTAPTLSPEHWKAVPPVSP 417
P SS + SP PP ASP KSG P +KT+ T SP K PP
Sbjct: 919 PPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPG-KKTSKTSSPGGKK--PP--- 972
Query: 418 ELRKPGPPLSPEIRSPAGS--PELRKPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGG 475
P P + I+S +G+ PE ++PS + K +P SP+ P + G
Sbjct: 973 ----PTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPG 1028
Query: 476 SPDLWKSSF-------FIEPQKPVFPETRKPG----PSGPSES----PKAASDIWKP--- 517
+L + + + PV K PS PS+S P +++ P
Sbjct: 1029 KLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIE 1088
Query: 518 ---VLSIDTEPRKPALFPEP-------AKTAPPASPEAR-------KRALFPEPRKHALF 560
V S +T P+ + P+P K APP + R + + +P +
Sbjct: 1089 IPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVV 1148
Query: 561 PEL---PKSALFSESQKAVELGDELQIDAIDDQKCDILVQEELLASPKKLLED-TLFPSS 616
P++ PKS+L + +L LQ +I + L A P ++D L P
Sbjct: 1149 PQVPTSPKSSLSVQPGFLADLNRTLQRKSI--TRHGSLSSRMSRAEPTATMDDMALPPPP 1206
Query: 617 KKLKKDNQES 626
+L D Q++
Sbjct: 1207 PELLSDQQKA 1216
Score = 60.1 bits (144), Expect = 8e-09
Identities = 93/412 (22%), Positives = 129/412 (31%), Gaps = 76/412 (18%)
Query: 214 SPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPW--GPSPAASPESRKSA 271
S S+ + SN Q S +T P +S V + E W G S ++R +
Sbjct: 539 SSSSIPESQSNHSNQSDSGVSDTQ-PAGHVRSQSIVSSVFSEAWKRGTQLEESSKARMES 597
Query: 272 RTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASS 331
P S P+ P+ A P P P P P P PP P P S + S+
Sbjct: 598 MNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSA 657
Query: 332 G----------------------------PWKPAKPAPSVSPGPWKP----IPSVSPGPW 359
G P P + SV P P +P P P
Sbjct: 658 GSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPP 717
Query: 360 KPTPSVSSASWKSSSVSPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPEL 419
PTP + A K + +PS P+ P L + + V+P
Sbjct: 718 PPTPGSAMAQLKPAPCAPSL---------------PQFSAPPPPLKIHQVQHITQVAPPT 762
Query: 420 RKPGPPLSPEIRSPAGSPELRKPSGSPDLWK-LSPDQRKTSPASLDFPESQKSSRGGSPD 478
P PP+ P P P+ +P K ++P + +P + P + P
Sbjct: 763 PPPPPPI-PAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPA 821
Query: 479 LWKSSFFIEPQKPVFPET--------RKPGPSGPSESPKAASDIWKPVLSIDTEP--RKP 528
+ P PV P T KP PS S P I T P
Sbjct: 822 SYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQ 881
Query: 529 ALFPEPAKTAPPASPEARKRALF--------------PEPRKHALFPELPKS 566
L P PA AP + P + + + P P +FP P S
Sbjct: 882 PLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPS 933
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 99.4 bits (246), Expect = 1e-20
Identities = 132/476 (27%), Positives = 173/476 (36%), Gaps = 82/476 (17%)
Query: 105 PVKSPPLPEHQKIPCN---------SAEPKSIPALSMETQKLGSVLS--PESPKPTPLTP 153
P SPPL +P + + P S P Q L S+ S P++P + + P
Sbjct: 451 PPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMP 510
Query: 154 -LEPQKPGSVVSPELQTP-----------LPS--PEPSKPASVSSPEPPKSVPVCESQKL 199
LE Q S+ P LQTP LPS P P + AS P P C
Sbjct: 511 PLETQS--SLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCP---- 564
Query: 200 APVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPV---------- 249
AP P P P P ++++ P PQ P PP P P+
Sbjct: 565 APCPLQAPPSPLTTPPPETPSSIATPPPQAP---PALASPPLQGLPSPPLSPLATPPPQA 621
Query: 250 ---LAASPEPWGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPAPA 306
LA P PSP ASP A +P P+ P+ PF SP P P A
Sbjct: 622 PPXLALPPLQAPPSPPASPPLSPLA---TPSPQAPNALAVHLLQAPF---SPPPSPPVQA 675
Query: 307 -VSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSV 365
SP + P P + P ++ PS ++ P + P+P SP PS +P P P P
Sbjct: 676 PFSPPASPPVSPSATPPSQAPPSLAAPPLQ-VPPSPPASP---PMSPSATPPPQAPPPLA 731
Query: 366 SSASWKSSSVSPSSWKSPPASPESW-KSGPPELRKTAPTLSPEHWKAVPPVSPELRKPGP 424
+ V PS SPP SP + P L P P A P+SP L KP P
Sbjct: 732 A----PPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSP-LAKPPP 786
Query: 425 PLSPEIRSPAGSPELRKPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGSPDLWKSSF 484
P + +P P+ P SP ASL P L
Sbjct: 787 QAPPALATPPLQALPSPPASFPGQAPFSPS------ASLPMSPLATPPPQAPPVLAAPLL 840
Query: 485 FIEPQKPVFP---ETRKPGPSGPSESPKAASDIWKPVLSIDTEPRKPALFPEPAKT 537
+ P P P R+P GP S + P L++ P P P P+++
Sbjct: 841 QVPPSPPASPTLQAPRRPPTPGPDTS------VSGPRLTLALAPGPP---PPPSRS 887
Score = 96.7 bits (239), Expect = 8e-20
Identities = 139/538 (25%), Positives = 201/538 (37%), Gaps = 111/538 (20%)
Query: 95 PKNQLNKETDPVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKPTPLTPL 154
P+ P+ S PL + + + +P L + L P P TPL PL
Sbjct: 288 PRKDAAPALGPLSSSPLATPSP---SGTKARPVPPPDNAATPLPATLPPSPPLATPL-PL 343
Query: 155 EPQKPGSVVSPELQTPLPSPEPSKPASVSSPE---PPKSVPVCESQKLAPVPSPE----P 207
P P + P LQT LPSP P+ P S + P PP P Q + P+ P P
Sbjct: 344 APPSPSA--PPSLQT-LPSP-PATPPSQAPPSMTTPPMQAPP-SLQTIPPIQVPHSLTSP 398
Query: 208 QKPAPVSP---ESVKATLSNPKPQKQS-HFPETLGP------------PSASSPESPVL- 250
AP SP S++AT S P Q+ H T+ P P+++ P+SP L
Sbjct: 399 SLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQ 458
Query: 251 ------AASPEPWGPSPAASP----------ESRKSARTTSPEP---------------- 278
A+ P SPA SP ++ S + SP+
Sbjct: 459 APLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSL 518
Query: 279 -----RKPSPSESPEPWKPFPAVSPEPRRPA--PAVSPGSWKPGPPGSPRPWKSNPSASS 331
+ P S + P + P+++P P + A P +P P P +P P ++ PS +
Sbjct: 519 APPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCP-APCPLQAPPSPLT 577
Query: 332 GPWKPAKPAPSVSPGPWKPIPSVSPGPWK--PTPSVSSASWKSSSVSPSSWKSPPASPES 389
P P P+ +P P P P+++ P + P+P +S + P P +P S
Sbjct: 578 TP-PPETPSSIATPPPQAP-PALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPS 635
Query: 390 WKSGPPELRKTAPTLSPEHWKAV--------PPVSPELRKP-GPPLSPEIRSPAGSPELR 440
+ PP P+ + AV PP SP ++ P PP SP + SP+ +P
Sbjct: 636 PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV-SPSATP--- 691
Query: 441 KPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGSPDLWKSSFFIEPQKPVFPETRKPG 500
PS +P P Q SP P S S +P P V P
Sbjct: 692 -PSQAPPSLAAPPLQVPPSP-----PASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASP 745
Query: 501 PSGPSESPKAASDIWKPVLSIDTEPRKPALFPEPAKTAPPASPEARKRALFPEPRKHA 558
P PS +P PR P L P PP+ P + + +P A
Sbjct: 746 PMSPSATPP---------------PRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQA 788
Score = 89.0 bits (219), Expect = 2e-17
Identities = 104/380 (27%), Positives = 149/380 (39%), Gaps = 51/380 (13%)
Query: 105 PVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPE---SPKPTPLTPLE------ 155
P PP P Q A P P+ + +Q S+ +P P P P+
Sbjct: 664 PFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPP 723
Query: 156 PQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQKPAPVSP 215
PQ P + +P LQ P PSP S P S S+ PP+ P+ + L PSP P+SP
Sbjct: 724 PQAPPPLAAPPLQVP-PSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPAS--LPMSP 780
Query: 216 ESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPAASPESRKSARTTS 275
L+ P PQ PP+ ++P L A P P P +P S ++ S
Sbjct: 781 ------LAKPPPQ---------APPALATPP---LQALPSPPASFPGQAPFSPSASLPMS 822
Query: 276 PEPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWK 335
P P P P P V P+P SP P P +P P ++ SGP
Sbjct: 823 P-LATPPPQAPPVLAAPLLQVP-----PSPPASPTLQAPRRPPTPGP----DTSVSGP-- 870
Query: 336 PAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPPASPESWKSGPP 395
+ +++PGP P PS SP P ++ S S++ +P + + PE + P
Sbjct: 871 --RLTLALAPGP-PPPPSRSPSSTLSGPDLAGHS-SSATSTPEELRGYDSGPEGGAAASP 926
Query: 396 ELRKTAPTLSPEHWKAVPPVSPELRKPGPPLSPEIRSPAGSPELRKPSGSPDLWKL-SPD 454
P W P +P L G P +P PA P G +++ P+
Sbjct: 927 PPDAELAACHPAAWSRGP--APPLAFRGAPGAPLPWPPATGP--GSADGLCTIYETEGPE 982
Query: 455 QRKTSPASLDFPESQKSSRG 474
+P +LD S +S G
Sbjct: 983 SATPAPGALDPGPSPGTSGG 1002
Score = 81.6 bits (200), Expect = 3e-15
Identities = 130/546 (23%), Positives = 196/546 (35%), Gaps = 102/546 (18%)
Query: 86 ASPDKWNDKPKNQLNKETDPVKSPPLPEHQKIPC--------------NSAEPKSIPALS 131
A P + P+ ++ ++ + P P ++ P +SA P S PA S
Sbjct: 196 ARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARS 255
Query: 132 METQK--LGSVLSPESPKPTPLTPLEPQKP-----------GSVVSPELQTPLPSPEPSK 178
+ + + P PKP L L P + G + S L TP PS ++
Sbjct: 256 GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKAR 315
Query: 179 PA-----------SVSSPEPPKSVPV-------CESQKLAPVPSPEPQKPAPVSPESVKA 220
P + P PP + P+ L +PSP P P +P S+
Sbjct: 316 PVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSP-PATPPSQAPPSMTT 374
Query: 221 TLSNPKPQKQS----HFPETLGPPSASSPESPVLAASPEPWGPSPAASPESRKSARTTSP 276
P Q+ P +L PS +P SP+ +S + + + ++ S T SP
Sbjct: 375 PPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSP 434
Query: 277 --------EPRKP--SPSESPEPWKP--FPAVSPEPRRPAPAVSP--------------- 309
P +P +P +SP P PA P +PAVSP
Sbjct: 435 RQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSS 494
Query: 310 -GSWKPGPPGSP--RPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVS 366
S P P S P S+ + P PA +P P + +PS++P P +
Sbjct: 495 LASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTP-PLENLPSLAPPPLQTA---- 549
Query: 367 SASWKSSSVSPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPELRKPGPPL 426
S+ ++ ++PP PP T P +P PP +P PPL
Sbjct: 550 -----SAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPP-ALASPPL 603
Query: 427 SPEIRSPAGSPELRKPSGSPDLWKLSPDQRKTSP------ASLDFPESQKSSRGGSPDLW 480
+ SP SP P +P L P Q SP + L P S ++ + L
Sbjct: 604 Q-GLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATP-SPQAPNALAVHLL 661
Query: 481 KSSFFIEPQKPVFPETRKPG--PSGPSESPKAASDIWKPVLSIDTEPRKPALFP-EPAKT 537
++ F P PV P P PS +P + + + P PA P P+ T
Sbjct: 662 QAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT 721
Query: 538 APPASP 543
PP +P
Sbjct: 722 PPPQAP 727
Score = 78.6 bits (192), Expect = 2e-14
Identities = 131/483 (27%), Positives = 179/483 (37%), Gaps = 89/483 (18%)
Query: 143 PESPKPTPLTPLEPQKPGSVVSPELQ--TPLPSPEPSKPASVSSPEPPKSVPVCESQKLA 200
P S + P + PG V SP T P P K +S+ E E+ K +
Sbjct: 95 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 154
Query: 201 PVPS--------PEPQKPAPVSPESVKAT-----LSNPKPQKQSHFPETLGPPSASSPES 247
+ + P P P+P +A L P P + P T GP + S S
Sbjct: 155 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPR-PPTEGPRKSVSSAS 213
Query: 248 PVLAASPEPWG---PSPAAS---PESRKSARTTSP-------------EPRKPSPSESPE 288
P P PS P SR + + +P PR P+ P+
Sbjct: 214 EHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPK 273
Query: 289 P-----WKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSV 343
P +P P V+P + APA+ P S P SP K+ P P A P P+
Sbjct: 274 PKGLQALRP-PQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPP--PDNAATPLPAT 330
Query: 344 ---SPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPPASPESWKSGPPELRKT 400
SP P+P P P P PS+ + SPPA+P S PP + T
Sbjct: 331 LPPSPPLATPLPLAPPSPSAP-PSLQTLP------------SPPATPPS--QAPPSMT-T 374
Query: 401 APTLSPEHWKAVPPV-------SPELRKPGPPL---SPEIRSPAGSPELRKPSGSPDLWK 450
P +P + +PP+ SP L+ P PL S + + GSP L+ +
Sbjct: 375 PPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQ---ATHSFLT 431
Query: 451 LSPDQRKTS------PASL--DFPESQKS-SRGGSPDLWKS-SFFIEP-QKPVFPETRKP 499
+SP Q + S PAS D P Q S SP L S S + P P+ +
Sbjct: 432 MSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQA 491
Query: 500 GPSGPSESPKA-ASDIWKPVLSIDTEPRKPALFPEPAKTAPPASPEARKRALFPEPRKHA 558
S S SP+A S + P L + P+L PA P P +L P P + A
Sbjct: 492 LSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTP--PLENLPSLAPPPLQTA 549
Query: 559 LFP 561
P
Sbjct: 550 SAP 552
Score = 67.8 bits (164), Expect = 4e-11
Identities = 112/419 (26%), Positives = 157/419 (37%), Gaps = 62/419 (14%)
Query: 199 LAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWG 258
L P P P+ P PV+P +++ + ++ G A+ PES A G
Sbjct: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
Query: 259 PS---PAASP------ESRKSARTTSPEPRKPSPSESPEPWKPFP------AVSPE---- 299
S PA+ P E A+ TSP P SP + +P P +S E
Sbjct: 85 TSSRNPASRPPASGRGERAPPAKNTSPGP-VSSPGRASGTTRPGPLGQKGLRISAEETVA 143
Query: 300 -------PRRPAPAVSPGSWKPGP-PGSPRPWKSNPSASSGPWKP-AKPAPSVSPGPWKP 350
P+R A + GP PG+P P + S ++G +PAPS P P
Sbjct: 144 RGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRP--- 200
Query: 351 IPSVSPGPWKPTPSVSSASWKSSS-VSPSSWKSPPASPESWKSGPPELRKTAPTLSPEHW 409
+ GP K SVSSAS S++ SP++ + P A + L +A LS
Sbjct: 201 ---PTEGPRK---SVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA- 253
Query: 410 KAVPPVSPELRKPGPPLSPEIRSPAGSPELRKPSGSPDLWKLSP--DQRKTSPASLDFPE 467
++ P R P P P+ P G LR P +P +P +SP + P
Sbjct: 254 RSGPSARGTPRAPAHPSQPK---PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS 310
Query: 468 SQKSSRGGSPDLWKSSFFIEPQKPVFPETRKPGPSGPSESPKAASDIWKPVLSIDTEPRK 527
K+ PD ++ + P P P P P SP A S+ T P
Sbjct: 311 GTKARPVPPPD--NAATPLPATLPPSPPLATPLPLAP-PSPSAPP-------SLQTLPSP 360
Query: 528 PALFPE---PAKTAPPASPEARKRALFPEPRKHAL-FPEL---PKSALFSESQKAVELG 579
PA P P+ T PP + + P H+L P L P S Q LG
Sbjct: 361 PATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLG 419
Score = 62.8 bits (151), Expect = 1e-09
Identities = 83/321 (25%), Positives = 112/321 (34%), Gaps = 96/321 (29%)
Query: 105 PVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKPTPLTPLEPQKPGSVVS 164
P SPP+ P + P + P L + S P SP TP P+ P + +
Sbjct: 710 PPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPAS--PPMSPSATP----PPRVPPLLAA 763
Query: 165 PELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQKP--APVSPESV--KA 220
P LQ P PSP S P S + PP++ P + L +PSP P AP SP + +
Sbjct: 764 PPLQVP-PSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMS 822
Query: 221 TLSNPKPQ----------------------KQSHFPETLGPPSASSPESPVLAASPEPWG 258
L+ P PQ + P T GP ++ S LA +P P
Sbjct: 823 PLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP-P 881
Query: 259 PSPAASPES---------RKSARTTSPEP------------------------------- 278
P P+ SP S S+ T++PE
Sbjct: 882 PPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWS 941
Query: 279 RKPSPS-------ESPEPWKP-------------FPAVSPEPRRPAP-AVSPGSWKPGPP 317
R P+P +P PW P + PE PAP A+ PG PG
Sbjct: 942 RGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGP-SPGTS 1000
Query: 318 GSPRPWKSNPSASSGPWKPAK 338
G + ASS K A+
Sbjct: 1001 GGKAAAGAGAGASSRSPKQAR 1021
Score = 35.8 bits (81), Expect = 0.16
Identities = 66/276 (23%), Positives = 97/276 (35%), Gaps = 36/276 (13%)
Query: 301 RRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWK 360
R PA A +PG P PPGSPRP P + + A +V P G
Sbjct: 15 RTPA-ARAPGLLTPRPPGSPRP---PPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATI 70
Query: 361 PTPSVSSASWKSSSVSPSSWKS-PPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPEL 419
P + + +S+ S + S PPAS ++ P + P SP P L
Sbjct: 71 PESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGP-L 129
Query: 420 RKPGPPLSPEIRSPAG-----------SPELRKPSGSPDLWKLSPDQRKTSPAS---LDF 465
+ G +S E G S R+ + P SP + S A+ +
Sbjct: 130 GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGL 189
Query: 466 PESQKSSRGGSPDLWKSSFFIEPQKPVFP----ETRKPGPSGPSESPKAASDIWKPVLSI 521
P S+R P P+K V T +P P+ P A + +P
Sbjct: 190 PRPAPSARPRPPT-------EGPRKSVSSASEHSTTEPSPAA-RRRPSAGGGLQRPASRS 241
Query: 522 DTEPRKPALFPEPAKTAPPA--SPEARKRALFPEPR 555
+ P PA++ P A +P A P+P+
Sbjct: 242 LSSSATP--LSSPARSGPSARGTPRAPAHPSQPKPK 275
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 99.0 bits (245), Expect = 2e-20
Identities = 117/409 (28%), Positives = 151/409 (36%), Gaps = 51/409 (12%)
Query: 82 TSKHASPDKWNDKPKNQLNKETDPVKSPPLPEHQ---KIPCNS-AEPKSIPALSME---T 134
T K K KP+ + P+P+ Q + P PKSI + E +
Sbjct: 190 TKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKS 249
Query: 135 QKLGSVLSPESPKPTPLT-----PLE-----PQ-KPGSVVSPELQTPLPSPEPSKPASVS 183
Q G+ + P TP T PL+ PQ K +V E P P PSKP +
Sbjct: 250 QPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKP-SLPSPSKPP-IQ 307
Query: 184 SPEPPKSVPVCESQKLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSAS 243
P P K A P E +P P P + + L+ P Q+ + PP +
Sbjct: 308 QPTPGKPP--------AQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTT 359
Query: 244 SPESPVLA-------------ASPEPWGPSPAASPESRKSARTTSPEPRKPSPSE--SPE 288
P + L S E GP A P P P KP + +P+
Sbjct: 360 KPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPK 419
Query: 289 PWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPW 348
P P + + P P +P +PGP P S+ P KP PS PGP
Sbjct: 420 PLAQQPGLQSPAKAPGPTKTPVQ-QPGPGKIPAQQAGPGKTSAQQTGPTKP-PSQLPGPA 477
Query: 349 KPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPPASPESWKSGPPELRKTAPTLSPEH 408
KP P PGP KP P S K S P S K PP P K P + T P S +
Sbjct: 478 KP-PPQQPGPAKPPPQ-QPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPP-SQQP 534
Query: 409 WKAVPPV-SPELRKPGPPLSPEIRSPAGSPE-LRKPSGSPDLWKLSPDQ 455
A P P KP S + S GS + L+ P+ SP K P Q
Sbjct: 535 GSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSA-KQPPSQ 582
Score = 89.0 bits (219), Expect = 2e-17
Identities = 157/672 (23%), Positives = 230/672 (34%), Gaps = 168/672 (25%)
Query: 92 NDKPKNQLNKETDPVKSPPLPEHQKIPCN--SAEPKSIPALSMETQKLGSVLSPESPKPT 149
N + K L + PV S P P+ + P SA KS P + K + +PK
Sbjct: 639 NCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDA-----APKQD 693
Query: 150 PLTPLEPQKPGSVVSPELQTPLPSPEPSKPA---SVSSPEPPKSVPVCESQKLAPVPSPE 206
EP+KP +V PS + +P S+S P PPK V Q APV +
Sbjct: 694 LSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDK 753
Query: 207 PQKPAPVSPESVKATLSN-------PKPQKQSHFPETLGPPSASSPESPVLA-------- 251
P++P V P + + S+ P + QS E PP + P +
Sbjct: 754 PKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKV 813
Query: 252 ------ASPEPWGPS-----PAASPESRKSARTTSP-----EPRKPSPSESPEP-WKPFP 294
A P P S P S ES K + P EP+K SP+P KP P
Sbjct: 814 SPFDSKAIPRPASDSKIISHPGPSSES-KGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMP 872
Query: 295 AVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSN---------------------------- 326
SP P P P + G P P SP+P + +
Sbjct: 873 KGSPTP--PGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGK 930
Query: 327 -----------------------PSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTP 363
P + SGP P K AP+ S P P S G P P
Sbjct: 931 LFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAP 990
Query: 364 SVSSASWK------SSSVSPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSP 417
+ S K + + P + ++P + PP + K + +L+ E KAV P
Sbjct: 991 AKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPI-KDSKSLTAEPQKAVLPTKL 1049
Query: 418 ELRKPGPPLSPEIRSPAGSPELRKPSGSPDLWKLSPDQR---------KTSPASLDFPE- 467
E + P PE P EL S P + + + +P + E
Sbjct: 1050 E-KSP----KPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEW 1104
Query: 468 ------SQKSSRGGSPDLWKSSFFIEPQKPVFPETRKPGPSGPSESPKAASDIWKPVLSI 521
+Q++ G D+ K P PSGP SP + +
Sbjct: 1105 LCLNCQTQRAISGQLGDIRK---------------MPPAPSGPKASP----------MPV 1139
Query: 522 DTEPRKPALFPEPAKTA-PPASPEARKRALFPEPRKHALFPELPKSALFSESQKAVELGD 580
TE KTA PP +K+ + + E K L E + D
Sbjct: 1140 PTE-------SSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTD 1192
Query: 581 ELQIDA-IDDQKCDILVQEELLASPKKLLED----------TLFPSSKKLKKDNQESSDA 629
+ Q ++ ++ K L +++ L KKL+ + L K +D + +A
Sbjct: 1193 QKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEA 1252
Query: 630 ELSSSEYIKTDL 641
+ S+ E K DL
Sbjct: 1253 KTSAPEEQKHDL 1264
Score = 88.6 bits (218), Expect = 2e-17
Identities = 150/583 (25%), Positives = 208/583 (35%), Gaps = 129/583 (22%)
Query: 101 KETDPVKSPPL-PEHQKIPCNSAEPKSIPALSME--TQKLGSVLSPESPKPT---PLTPL 154
++ P K P P H+K A+P + P+ + Q+ G+V P P T P PL
Sbjct: 307 QQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPL 366
Query: 155 EPQKP-----GSVVSPELQ--------------TPLPSPEPSKPAS--VSSPEPPKSVPV 193
P KP GS Q TP P P+KP + V +P+P P
Sbjct: 367 GPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPG 426
Query: 194 CESQKLAPVPSPEP---------------------QKPAPVSPESVKATLSNPKPQKQSH 232
+S AP P+ P Q+ P P S + P PQ+
Sbjct: 427 LQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGP 486
Query: 233 F-PETLGPPSASSPESPVLAASPEPWGPSPAA-SPESRKSARTTSPEPRKPSPS-ESPEP 289
P P SA P + P P P PA SP+ S + S +P PS + P P
Sbjct: 487 AKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSP 546
Query: 290 WKPFPAVSPEPRRPA--------PAVSPGSWKPGPPGSPR---------------PWKSN 326
KP S +P P VSP + +P G P+ P K+N
Sbjct: 547 AKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKAN 606
Query: 327 PSASSGPWKPAKPAPSVSPGP-------W---------------KPIPSVSPGPWKPTPS 364
+ + +P P W P+PS SP P T
Sbjct: 607 FNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPS-SPQPKLKTAP 665
Query: 365 VSSASWKSSSVSPSSWKSPP---ASPESWKSGPPELRKTAPTL-------SPEHWKAVPP 414
V++ S S S SP ++ P A+P+ S PE +K P + SP PP
Sbjct: 666 VTTTSAVSKS-SPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPP 724
Query: 415 VSPELRKPGPPLSPEIRSPAG-SPELRKPSGSPDLWKLSPDQRKTSPASL--DFPESQKS 471
+ L KP PP P + S +P P + K + D +S A+ D P S+
Sbjct: 725 EADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQ 784
Query: 472 SRG---GSPDLWKSSFFIEPQKPVFPETRKPGPSGPSESPKAASD---IWKPVLSIDTEP 525
S+ +P L S +P + P K P P+ ASD I P S +++
Sbjct: 785 SQAEEKTTPPLKTDS--AKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKG 842
Query: 526 RK---PALFPEPAKTA-------PPASPEARKRALFPEPRKHA 558
+K P E K A P A P + P PR A
Sbjct: 843 QKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTA 885
Score = 76.6 bits (187), Expect = 8e-14
Identities = 113/449 (25%), Positives = 163/449 (36%), Gaps = 94/449 (20%)
Query: 144 ESPKPTPLTPLEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVP 203
E+ K + E KP ++ P LQ +PPK P+P
Sbjct: 188 ETTKKQKVVQKEQGKPEGIIKPPLQQ----------------QPPK-----------PIP 220
Query: 204 SPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPAA 263
+ P+ + ++S+ +P+K P G P ++P + P A+
Sbjct: 221 KQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPL-QRDAS 279
Query: 264 SPESRKS--ARTTSPEPRKPSPS----ESPEPWKPFPAVSP--EPRRPAPAVSPGSWKPG 315
P+++++ R S +P PSPS + P P KP PA P E +P PA P
Sbjct: 280 RPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKP-PAQQPGHEKSQPGPAKPPAQ---- 334
Query: 316 PPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSV 375
P G +P P P +P PG KP P+ GP KP P+ + S K SS
Sbjct: 335 PSGLTKPLAQQPGTVKPPVQP--------PGTTKP-PAQPLGPAKP-PAQQTGSEKPSSE 384
Query: 376 SPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPELRKPGPPL----SPEIR 431
P P A + PP + KT P P P P ++ G P P ++
Sbjct: 385 QPG----PKALAQ-----PPGVGKT-PAQQPG------PAKPPTQQVGTPKPLAQQPGLQ 428
Query: 432 SPAGSPELRK-PSGSPDLWKLSPDQR---KTSPASLDFPESQKSSRGGSPDLWKSSFFIE 487
SPA +P K P P K+ Q KTS A P S G
Sbjct: 429 SPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTS-AQQTGPTKPPSQLPG------------ 475
Query: 488 PQKPVFPETRKPGPSGPSESPKAASDIWKPVLSIDTEPRKPALFPEPAKTAPPASPEARK 547
P P ++PGP+ P ++ KP + P P PAK +P +
Sbjct: 476 ---PAKPPPQQPGPAKPPPQQPGSA---KPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKP 529
Query: 548 RALFPEPRKHALFPELPKSALFSESQKAV 576
+ P K + P +S K V
Sbjct: 530 PSQQPGSAKPSAQQPSPAKPSAQQSTKPV 558
Score = 75.5 bits (184), Expect = 2e-13
Identities = 149/628 (23%), Positives = 215/628 (34%), Gaps = 117/628 (18%)
Query: 101 KETDPVKSPP-LPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKPTPLTP----LE 155
++T P K P LP K P P P + K S P S KP P P
Sbjct: 462 QQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQ-QPGSTKPPPQQPGPAKPS 520
Query: 156 PQKPGSVVSPELQ--TPLPS---PEPSKPASVSSPEP----------------------- 187
PQ+PGS P Q + PS P P+KP++ S +P
Sbjct: 521 PQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPP 580
Query: 188 ----PKSV-PVCE-SQKLAPVPSPEPQKPAPVSPESVKATLS-NPKPQ---------KQS 231
PK++ P+C ++ L VP +V + NP P
Sbjct: 581 SQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNC 640
Query: 232 HFPETLGPPSASSPESPVLAASPEPWGPSPAASPESRKSA-RTTSPEPRKPSPSESPEPW 290
LG A P SP P +P + SA +SP+P++ SP + P
Sbjct: 641 QMKRALGGDLAPVPSSP---------QPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAP- 690
Query: 291 KPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKP 350
K + +PEP++P P V +P GSP P + KPA P P
Sbjct: 691 KQDLSKAPEPKKPPPLVK----QPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDK 746
Query: 351 IPSVSPGPWKP---TPSVSSASWKSSSVSPSSWKSPPASPESWKSGPP----------EL 397
P P +P P+ S S++ P S S K+ PP
Sbjct: 747 APVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSF 806
Query: 398 RKTAPTLSPEHWKAVP----------------------PVSPELRKPGPPLSPEIRSPAG 435
T +SP KA+P V P +K P + SP
Sbjct: 807 PPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSP-- 864
Query: 436 SPELR-KPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGSPDLWK-----SSFFIEPQ 489
P+ + P GSP P +T P P+ Q+ SR S +L S PQ
Sbjct: 865 KPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQ 924
Query: 490 KPVFPETRKPGPSGPSESPKAASDIWKPVLSIDTEPRKPALFPEPAKTAPPAS--PEARK 547
+ V + G S S++ S +P + P P + PA + PP S P
Sbjct: 925 ETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAP-MKQAPAPSQPPTSQGPPKST 983
Query: 548 RALFPEPRKHALFPELPKSALFSESQKAVELGDELQIDAIDDQKCDILVQEELLASPKKL 607
P P K + K+ + + E ++ + + I + L A P+K
Sbjct: 984 GQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKA 1043
Query: 608 LEDTLFPSSKKLKKDNQESSDAELSSSE 635
+ T KL+K + S L +E
Sbjct: 1044 VLPT------KLEKSPKPESTCPLCKTE 1065
Score = 72.4 bits (176), Expect = 2e-12
Identities = 166/771 (21%), Positives = 259/771 (33%), Gaps = 195/771 (25%)
Query: 92 NDKPKN--QLNKETDPVKSPPLPEHQKIPCNS----AEPKSIPALSMETQKLGSVLSPES 145
+DKPK + TD V S IP + AE K+ P L ++ K P
Sbjct: 751 DDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTG 810
Query: 146 PKPTPLTPLEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVP-- 203
K +P +P S S + P PS E SK P K P K++P P
Sbjct: 811 EKVSPFDSKAIPRPASD-SKIISHPGPSSE-SKGQKQVDPVQKKEEPKKAQTKMSPKPDA 868
Query: 204 ------SPEPQKPAPVSPESVKATLSNPKPQKQS-------------------------- 231
SP P P P + ++V +PKPQ+QS
Sbjct: 869 KPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVT 928
Query: 232 ---------------HFPETLGPPSASSPESPVLAASPEPWGPSPAASPESRKSARTTSP 276
+ T G P S P +P P+P+ P S+ ++T
Sbjct: 929 GKLFGFGASIFSQASNLISTAGQPGPHSQSGP---GAPMKQAPAPSQPPTSQGPPKSTGQ 985
Query: 277 EPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKP 336
P P+P++S K A + E P +P + P P K + S ++ P K
Sbjct: 986 AP--PAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKA 1043
Query: 337 AKPAP-SVSPGPWKPIPSV-------SPGP------------------WKPTPSVSSAS- 369
P SP P P S P + PTP ++
Sbjct: 1044 VLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQE 1103
Query: 370 W--------KSSSVSPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPELRK 421
W ++ S + P +P SGP PT S AVPP ++K
Sbjct: 1104 WLCLNCQTQRAISGQLGDIRKMPPAP----SGPKASPMPVPTESSSQKTAVPPQVKLVKK 1159
Query: 422 PGPPLSPEIRSPAGSPELRKPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGSPDLWK 481
E+++ A L K + + K+ P E K+S
Sbjct: 1160 Q----EQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASA-------- 1207
Query: 482 SSFFIEPQKPVFPETRKPGPSGPSESPKAASDIWKPVLSIDTEPRKPALFPEPAKTAPPA 541
++ +KP+ PE +K P E K S+ KP+L E +KP PE K P A
Sbjct: 1208 ----LQEKKPL-PEEKKLIP----EEEKIRSEEKKPLL----EEKKPT--PEDKKLLPEA 1252
Query: 542 ---SPEARKRALF----------------PEPRKHALFPELPKSALFSESQKAVELGDEL 582
+PE +K L P+ + P+ L S + +++ D+
Sbjct: 1253 KTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDK 1312
Query: 583 QIDAI------------------------DDQKCDILVQEELLASPKKLLED-------- 610
I +D K D ++ SP+ L +
Sbjct: 1313 TTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQP-KSPQGLSDTGYSSDGIS 1371
Query: 611 -------TLFPSSKK-----LKKDNQESSDAELSSSEYIKTDLDAMDIKGQESSSDQEQV 658
+L P+ +K LKKD+ + S S+ K + + I ++S+
Sbjct: 1372 SSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQAST---LA 1428
Query: 659 DVESIDFSKENKMDMTSPEQSRNVLQFTEEKEAFISEEEIAKYMKRGKGKY 709
D +S ++ +++ P+ +E E ISEEEI + + K +
Sbjct: 1429 DEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTF 1479
Score = 54.3 bits (129), Expect = 4e-07
Identities = 87/338 (25%), Positives = 128/338 (37%), Gaps = 46/338 (13%)
Query: 116 KIPCNSAEPKSIPALSMETQKLGSV----LSPESPKPTPLTPLEPQKPGSVVSPELQTPL 171
++P S S+PA + S+ P P P P P P P P +P
Sbjct: 2375 QLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPK 2434
Query: 172 PSPEPSKPASVSSPEPP-----------KSVPVCESQKLAPVPSPEPQKPAPVSPESVKA 220
P+ P K +V+SP ++ V S L PV P PV P+
Sbjct: 2435 PTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGL-PVTRICTTAPPPVPPK---- 2489
Query: 221 TLSNPKPQKQSHFPETLGPPSASSPESPVL-AASPEPWGPSPAASPESRKSART----TS 275
S P +H PE PP A P P L + +P P + S S+ T TS
Sbjct: 2490 PSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTS 2549
Query: 276 PEPRKPSPSE--SPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGP 333
+ + PSP+ SP K P S ++ P PG+P ++ + +S P
Sbjct: 2550 ADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVIT----LPSEPGTPTDSSASQAITSWP 2605
Query: 334 -WKPAKPAPSVSPGPWKPIPSVS----PGPWKPTPSVSSASWKSSS---VSPSSWKSPPA 385
P+K SV P + +P V+ P + T +S A S+ +PSS+++ P
Sbjct: 2606 LGSPSKDLVSVEP-VFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQAAPT 2664
Query: 386 S------PESWKSGPPELRKTAPTLSPEHWKAVPPVSP 417
S E K+ R TAP++ P P
Sbjct: 2665 SVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEP 2702
Score = 47.4 bits (111), Expect = 5e-05
Identities = 96/391 (24%), Positives = 140/391 (35%), Gaps = 54/391 (13%)
Query: 187 PPKSV---PVCESQKLAPVPSPEP---QKPA---PVSPESVKATLSNPKPQKQSHFPETL 237
PP SV P+ E S E +KPA P SV + + P+P +S +
Sbjct: 2343 PPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDIS 2402
Query: 238 GPPSASSPESPVLAASPEPWGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVS 297
P P P P P P P P S K + SP + P F AV+
Sbjct: 2403 AQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPL--FDAVT 2460
Query: 298 PEP-----RRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKP-I 351
R V+ PP P+P S PS +P P ++P P P +
Sbjct: 2461 TLETTAVLRSNGLPVTRICTTAPPPVPPKP-SSIPSGLVFTHRPEPSKPPIAPKPVIPQL 2519
Query: 352 PSVSPGPW----KPTPSVSSASWKSSSVSPSSWKSP-PASPESWKSGPPELRKTAPTLSP 406
P+ + P KPT ++S + V+ + +K P P SP S P K++P S
Sbjct: 2520 PTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLS-----PHSNKSSPRFS- 2573
Query: 407 EHWKAVPPVSPELRKPGPPLSPEIRSPAGSPELRKPSGSP--DLWKLSPDQRKTSP-ASL 463
K++ + P P +P S A P GSP DL + P P ++
Sbjct: 2574 ---KSLTETYVVITLPSEPGTP-TDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAV 2629
Query: 464 DFPESQKSSRGGSPDLWKSSFFIEPQKPVFPETRKPGPSGPSESPKAASDIWKPVLSIDT 523
+ P S + +F+I F T PS +P + + + T
Sbjct: 2630 EIPISS-----------EQTFYISGALQTFSATPVTAPSSFQAAPTSVTQF------LTT 2672
Query: 524 EPRKPALFPEPAKTAPPASPEARKRALFPEP 554
E K + TAP + + PEP
Sbjct: 2673 EVSKTEV-SATRSTAPSVGLSSISITIPPEP 2702
Score = 35.4 bits (80), Expect = 0.21
Identities = 42/211 (19%), Positives = 80/211 (37%), Gaps = 35/211 (16%)
Query: 103 TDPVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKPTPL---------TP 153
T+ K+ PL + +S +++ +S++T+ +G++ +P P
Sbjct: 3502 TEADKTKPLSK-----VSSIAVQTVAEISVQTEPVGTIRTPSIRARVDAKVEIIKHISAP 3556
Query: 154 LEPQKPGSV-----VSPELQTPLPSPEPSKPASVSSPEP-----PKSVPVCESQKLAPVP 203
+ K GS+ + Q+P S P P P + + +LAP P
Sbjct: 3557 EKTYKGGSLGCQTEADSDTQSPQYLSATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSP 3616
Query: 204 SPEPQKP-APVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPA 262
P+ +P+SP S L + + P+ + P P+ + P
Sbjct: 3617 PKSPKVLYSPISPLSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKV----------PP 3666
Query: 263 ASPESRKSARTTSPEPRKPSPSESPEPWKPF 293
ASP++ K + + +P+ SP+ PF
Sbjct: 3667 ASPKTAKMMQRSMSDPKPLSPTADESSRAPF 3697
Score = 30.0 bits (66), Expect = 9.0
Identities = 43/174 (24%), Positives = 56/174 (32%), Gaps = 20/174 (11%)
Query: 139 SVLSPESPKPTPLTPLEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQK 198
S SP K P TPLE + + PSP P P + SP P S
Sbjct: 3582 SATSPPKDKKRP-TPLEIGYSSHLRADSTVQLAPSP-PKSPKVLYSPISPLSPGKALESA 3639
Query: 199 LAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWG 258
P P P + PQK H PP++ + + +P
Sbjct: 3640 FVPYEKPLPD---------------DISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKP 3684
Query: 259 PSPAASPESRKSARTTSPEPRKPSPS-ESPEPWKPFPAVSPEPRRPAPAVSPGS 311
SP A SR + T K S + S K P P P +S G+
Sbjct: 3685 LSPTADESSRAPFQYTEGYTTKGSQTMTSSGAQKKVKRTLPNP--PPEEISTGT 3736
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 99.0 bits (245), Expect = 2e-20
Identities = 117/409 (28%), Positives = 151/409 (36%), Gaps = 51/409 (12%)
Query: 82 TSKHASPDKWNDKPKNQLNKETDPVKSPPLPEHQ---KIPCNS-AEPKSIPALSME---T 134
T K K KP+ + P+P+ Q + P PKSI + E +
Sbjct: 190 TKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKS 249
Query: 135 QKLGSVLSPESPKPTPLT-----PLE-----PQ-KPGSVVSPELQTPLPSPEPSKPASVS 183
Q G+ + P TP T PL+ PQ K +V E P P PSKP +
Sbjct: 250 QPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKP-SLPSPSKPP-IQ 307
Query: 184 SPEPPKSVPVCESQKLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSAS 243
P P K A P E +P P P + + L+ P Q+ + PP +
Sbjct: 308 QPTPGKPP--------AQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTT 359
Query: 244 SPESPVLA-------------ASPEPWGPSPAASPESRKSARTTSPEPRKPSPSE--SPE 288
P + L S E GP A P P P KP + +P+
Sbjct: 360 KPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPK 419
Query: 289 PWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPW 348
P P + + P P +P +PGP P S+ P KP PS PGP
Sbjct: 420 PLAQQPGLQSPAKAPGPTKTPVQ-QPGPGKIPAQQAGPGKTSAQQTGPTKP-PSQLPGPA 477
Query: 349 KPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPPASPESWKSGPPELRKTAPTLSPEH 408
KP P PGP KP P S K S P S K PP P K P + T P S +
Sbjct: 478 KP-PPQQPGPAKPPPQ-QPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPP-SQQP 534
Query: 409 WKAVPPV-SPELRKPGPPLSPEIRSPAGSPE-LRKPSGSPDLWKLSPDQ 455
A P P KP S + S GS + L+ P+ SP K P Q
Sbjct: 535 GSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSA-KQPPSQ 582
Score = 89.0 bits (219), Expect = 2e-17
Identities = 157/672 (23%), Positives = 230/672 (34%), Gaps = 168/672 (25%)
Query: 92 NDKPKNQLNKETDPVKSPPLPEHQKIPCN--SAEPKSIPALSMETQKLGSVLSPESPKPT 149
N + K L + PV S P P+ + P SA KS P + K + +PK
Sbjct: 639 NCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDA-----APKQD 693
Query: 150 PLTPLEPQKPGSVVSPELQTPLPSPEPSKPA---SVSSPEPPKSVPVCESQKLAPVPSPE 206
EP+KP +V PS + +P S+S P PPK V Q APV +
Sbjct: 694 LSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDK 753
Query: 207 PQKPAPVSPESVKATLSN-------PKPQKQSHFPETLGPPSASSPESPVLA-------- 251
P++P V P + + S+ P + QS E PP + P +
Sbjct: 754 PKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKV 813
Query: 252 ------ASPEPWGPS-----PAASPESRKSARTTSP-----EPRKPSPSESPEP-WKPFP 294
A P P S P S ES K + P EP+K SP+P KP P
Sbjct: 814 SPFDSKAIPRPASDSKIISHPGPSSES-KGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMP 872
Query: 295 AVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSN---------------------------- 326
SP P P P + G P P SP+P + +
Sbjct: 873 KGSPTP--PGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGK 930
Query: 327 -----------------------PSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTP 363
P + SGP P K AP+ S P P S G P P
Sbjct: 931 LFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAP 990
Query: 364 SVSSASWK------SSSVSPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSP 417
+ S K + + P + ++P + PP + K + +L+ E KAV P
Sbjct: 991 AKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPI-KDSKSLTAEPQKAVLPTKL 1049
Query: 418 ELRKPGPPLSPEIRSPAGSPELRKPSGSPDLWKLSPDQR---------KTSPASLDFPE- 467
E + P PE P EL S P + + + +P + E
Sbjct: 1050 E-KSP----KPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEW 1104
Query: 468 ------SQKSSRGGSPDLWKSSFFIEPQKPVFPETRKPGPSGPSESPKAASDIWKPVLSI 521
+Q++ G D+ K P PSGP SP + +
Sbjct: 1105 LCLNCQTQRAISGQLGDIRK---------------MPPAPSGPKASP----------MPV 1139
Query: 522 DTEPRKPALFPEPAKTA-PPASPEARKRALFPEPRKHALFPELPKSALFSESQKAVELGD 580
TE KTA PP +K+ + + E K L E + D
Sbjct: 1140 PTE-------SSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTD 1192
Query: 581 ELQIDA-IDDQKCDILVQEELLASPKKLLED----------TLFPSSKKLKKDNQESSDA 629
+ Q ++ ++ K L +++ L KKL+ + L K +D + +A
Sbjct: 1193 QKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEA 1252
Query: 630 ELSSSEYIKTDL 641
+ S+ E K DL
Sbjct: 1253 KTSAPEEQKHDL 1264
Score = 88.6 bits (218), Expect = 2e-17
Identities = 150/583 (25%), Positives = 208/583 (35%), Gaps = 129/583 (22%)
Query: 101 KETDPVKSPPL-PEHQKIPCNSAEPKSIPALSME--TQKLGSVLSPESPKPT---PLTPL 154
++ P K P P H+K A+P + P+ + Q+ G+V P P T P PL
Sbjct: 307 QQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPL 366
Query: 155 EPQKP-----GSVVSPELQ--------------TPLPSPEPSKPAS--VSSPEPPKSVPV 193
P KP GS Q TP P P+KP + V +P+P P
Sbjct: 367 GPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPG 426
Query: 194 CESQKLAPVPSPEP---------------------QKPAPVSPESVKATLSNPKPQKQSH 232
+S AP P+ P Q+ P P S + P PQ+
Sbjct: 427 LQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGP 486
Query: 233 F-PETLGPPSASSPESPVLAASPEPWGPSPAA-SPESRKSARTTSPEPRKPSPS-ESPEP 289
P P SA P + P P P PA SP+ S + S +P PS + P P
Sbjct: 487 AKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSP 546
Query: 290 WKPFPAVSPEPRRPA--------PAVSPGSWKPGPPGSPR---------------PWKSN 326
KP S +P P VSP + +P G P+ P K+N
Sbjct: 547 AKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKAN 606
Query: 327 PSASSGPWKPAKPAPSVSPGP-------W---------------KPIPSVSPGPWKPTPS 364
+ + +P P W P+PS SP P T
Sbjct: 607 FNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPS-SPQPKLKTAP 665
Query: 365 VSSASWKSSSVSPSSWKSPP---ASPESWKSGPPELRKTAPTL-------SPEHWKAVPP 414
V++ S S S SP ++ P A+P+ S PE +K P + SP PP
Sbjct: 666 VTTTSAVSKS-SPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPP 724
Query: 415 VSPELRKPGPPLSPEIRSPAG-SPELRKPSGSPDLWKLSPDQRKTSPASL--DFPESQKS 471
+ L KP PP P + S +P P + K + D +S A+ D P S+
Sbjct: 725 EADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQ 784
Query: 472 SRG---GSPDLWKSSFFIEPQKPVFPETRKPGPSGPSESPKAASD---IWKPVLSIDTEP 525
S+ +P L S +P + P K P P+ ASD I P S +++
Sbjct: 785 SQAEEKTTPPLKTDS--AKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKG 842
Query: 526 RK---PALFPEPAKTA-------PPASPEARKRALFPEPRKHA 558
+K P E K A P A P + P PR A
Sbjct: 843 QKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTA 885
Score = 76.6 bits (187), Expect = 8e-14
Identities = 113/449 (25%), Positives = 163/449 (36%), Gaps = 94/449 (20%)
Query: 144 ESPKPTPLTPLEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVP 203
E+ K + E KP ++ P LQ +PPK P+P
Sbjct: 188 ETTKKQKVVQKEQGKPEGIIKPPLQQ----------------QPPK-----------PIP 220
Query: 204 SPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPAA 263
+ P+ + ++S+ +P+K P G P ++P + P A+
Sbjct: 221 KQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPL-QRDAS 279
Query: 264 SPESRKS--ARTTSPEPRKPSPS----ESPEPWKPFPAVSP--EPRRPAPAVSPGSWKPG 315
P+++++ R S +P PSPS + P P KP PA P E +P PA P
Sbjct: 280 RPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKP-PAQQPGHEKSQPGPAKPPAQ---- 334
Query: 316 PPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSV 375
P G +P P P +P PG KP P+ GP KP P+ + S K SS
Sbjct: 335 PSGLTKPLAQQPGTVKPPVQP--------PGTTKP-PAQPLGPAKP-PAQQTGSEKPSSE 384
Query: 376 SPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPELRKPGPPL----SPEIR 431
P P A + PP + KT P P P P ++ G P P ++
Sbjct: 385 QPG----PKALAQ-----PPGVGKT-PAQQPG------PAKPPTQQVGTPKPLAQQPGLQ 428
Query: 432 SPAGSPELRK-PSGSPDLWKLSPDQR---KTSPASLDFPESQKSSRGGSPDLWKSSFFIE 487
SPA +P K P P K+ Q KTS A P S G
Sbjct: 429 SPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTS-AQQTGPTKPPSQLPG------------ 475
Query: 488 PQKPVFPETRKPGPSGPSESPKAASDIWKPVLSIDTEPRKPALFPEPAKTAPPASPEARK 547
P P ++PGP+ P ++ KP + P P PAK +P +
Sbjct: 476 ---PAKPPPQQPGPAKPPPQQPGSA---KPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKP 529
Query: 548 RALFPEPRKHALFPELPKSALFSESQKAV 576
+ P K + P +S K V
Sbjct: 530 PSQQPGSAKPSAQQPSPAKPSAQQSTKPV 558
Score = 75.5 bits (184), Expect = 2e-13
Identities = 149/628 (23%), Positives = 215/628 (34%), Gaps = 117/628 (18%)
Query: 101 KETDPVKSPP-LPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKPTPLTP----LE 155
++T P K P LP K P P P + K S P S KP P P
Sbjct: 462 QQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQ-QPGSTKPPPQQPGPAKPS 520
Query: 156 PQKPGSVVSPELQ--TPLPS---PEPSKPASVSSPEP----------------------- 187
PQ+PGS P Q + PS P P+KP++ S +P
Sbjct: 521 PQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPP 580
Query: 188 ----PKSV-PVCE-SQKLAPVPSPEPQKPAPVSPESVKATLS-NPKPQ---------KQS 231
PK++ P+C ++ L VP +V + NP P
Sbjct: 581 SQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNC 640
Query: 232 HFPETLGPPSASSPESPVLAASPEPWGPSPAASPESRKSA-RTTSPEPRKPSPSESPEPW 290
LG A P SP P +P + SA +SP+P++ SP + P
Sbjct: 641 QMKRALGGDLAPVPSSP---------QPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAP- 690
Query: 291 KPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKP 350
K + +PEP++P P V +P GSP P + KPA P P
Sbjct: 691 KQDLSKAPEPKKPPPLVK----QPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDK 746
Query: 351 IPSVSPGPWKP---TPSVSSASWKSSSVSPSSWKSPPASPESWKSGPP----------EL 397
P P +P P+ S S++ P S S K+ PP
Sbjct: 747 APVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSF 806
Query: 398 RKTAPTLSPEHWKAVP----------------------PVSPELRKPGPPLSPEIRSPAG 435
T +SP KA+P V P +K P + SP
Sbjct: 807 PPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSP-- 864
Query: 436 SPELR-KPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGSPDLWK-----SSFFIEPQ 489
P+ + P GSP P +T P P+ Q+ SR S +L S PQ
Sbjct: 865 KPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQ 924
Query: 490 KPVFPETRKPGPSGPSESPKAASDIWKPVLSIDTEPRKPALFPEPAKTAPPAS--PEARK 547
+ V + G S S++ S +P + P P + PA + PP S P
Sbjct: 925 ETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAP-MKQAPAPSQPPTSQGPPKST 983
Query: 548 RALFPEPRKHALFPELPKSALFSESQKAVELGDELQIDAIDDQKCDILVQEELLASPKKL 607
P P K + K+ + + E ++ + + I + L A P+K
Sbjct: 984 GQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKA 1043
Query: 608 LEDTLFPSSKKLKKDNQESSDAELSSSE 635
+ T KL+K + S L +E
Sbjct: 1044 VLPT------KLEKSPKPESTCPLCKTE 1065
Score = 72.4 bits (176), Expect = 2e-12
Identities = 166/771 (21%), Positives = 259/771 (33%), Gaps = 195/771 (25%)
Query: 92 NDKPKN--QLNKETDPVKSPPLPEHQKIPCNS----AEPKSIPALSMETQKLGSVLSPES 145
+DKPK + TD V S IP + AE K+ P L ++ K P
Sbjct: 751 DDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTG 810
Query: 146 PKPTPLTPLEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVP-- 203
K +P +P S S + P PS E SK P K P K++P P
Sbjct: 811 EKVSPFDSKAIPRPASD-SKIISHPGPSSE-SKGQKQVDPVQKKEEPKKAQTKMSPKPDA 868
Query: 204 ------SPEPQKPAPVSPESVKATLSNPKPQKQS-------------------------- 231
SP P P P + ++V +PKPQ+QS
Sbjct: 869 KPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVT 928
Query: 232 ---------------HFPETLGPPSASSPESPVLAASPEPWGPSPAASPESRKSARTTSP 276
+ T G P S P +P P+P+ P S+ ++T
Sbjct: 929 GKLFGFGASIFSQASNLISTAGQPGPHSQSGP---GAPMKQAPAPSQPPTSQGPPKSTGQ 985
Query: 277 EPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKP 336
P P+P++S K A + E P +P + P P K + S ++ P K
Sbjct: 986 AP--PAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKA 1043
Query: 337 AKPAP-SVSPGPWKPIPSV-------SPGP------------------WKPTPSVSSAS- 369
P SP P P S P + PTP ++
Sbjct: 1044 VLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQE 1103
Query: 370 W--------KSSSVSPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPELRK 421
W ++ S + P +P SGP PT S AVPP ++K
Sbjct: 1104 WLCLNCQTQRAISGQLGDIRKMPPAP----SGPKASPMPVPTESSSQKTAVPPQVKLVKK 1159
Query: 422 PGPPLSPEIRSPAGSPELRKPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGSPDLWK 481
E+++ A L K + + K+ P E K+S
Sbjct: 1160 Q----EQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASA-------- 1207
Query: 482 SSFFIEPQKPVFPETRKPGPSGPSESPKAASDIWKPVLSIDTEPRKPALFPEPAKTAPPA 541
++ +KP+ PE +K P E K S+ KP+L E +KP PE K P A
Sbjct: 1208 ----LQEKKPL-PEEKKLIP----EEEKIRSEEKKPLL----EEKKPT--PEDKKLLPEA 1252
Query: 542 ---SPEARKRALF----------------PEPRKHALFPELPKSALFSESQKAVELGDEL 582
+PE +K L P+ + P+ L S + +++ D+
Sbjct: 1253 KTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDK 1312
Query: 583 QIDAI------------------------DDQKCDILVQEELLASPKKLLED-------- 610
I +D K D ++ SP+ L +
Sbjct: 1313 TTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQP-KSPQGLSDTGYSSDGIS 1371
Query: 611 -------TLFPSSKK-----LKKDNQESSDAELSSSEYIKTDLDAMDIKGQESSSDQEQV 658
+L P+ +K LKKD+ + S S+ K + + I ++S+
Sbjct: 1372 SSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQAST---LA 1428
Query: 659 DVESIDFSKENKMDMTSPEQSRNVLQFTEEKEAFISEEEIAKYMKRGKGKY 709
D +S ++ +++ P+ +E E ISEEEI + + K +
Sbjct: 1429 DEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTF 1479
Score = 54.3 bits (129), Expect = 4e-07
Identities = 87/338 (25%), Positives = 128/338 (37%), Gaps = 46/338 (13%)
Query: 116 KIPCNSAEPKSIPALSMETQKLGSV----LSPESPKPTPLTPLEPQKPGSVVSPELQTPL 171
++P S S+PA + S+ P P P P P P P P +P
Sbjct: 2375 QLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPK 2434
Query: 172 PSPEPSKPASVSSPEPP-----------KSVPVCESQKLAPVPSPEPQKPAPVSPESVKA 220
P+ P K +V+SP ++ V S L PV P PV P+
Sbjct: 2435 PTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGL-PVTRICTTAPPPVPPK---- 2489
Query: 221 TLSNPKPQKQSHFPETLGPPSASSPESPVL-AASPEPWGPSPAASPESRKSART----TS 275
S P +H PE PP A P P L + +P P + S S+ T TS
Sbjct: 2490 PSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTS 2549
Query: 276 PEPRKPSPSE--SPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGP 333
+ + PSP+ SP K P S ++ P PG+P ++ + +S P
Sbjct: 2550 ADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVIT----LPSEPGTPTDSSASQAITSWP 2605
Query: 334 -WKPAKPAPSVSPGPWKPIPSVS----PGPWKPTPSVSSASWKSSS---VSPSSWKSPPA 385
P+K SV P + +P V+ P + T +S A S+ +PSS+++ P
Sbjct: 2606 LGSPSKDLVSVEP-VFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQAAPT 2664
Query: 386 S------PESWKSGPPELRKTAPTLSPEHWKAVPPVSP 417
S E K+ R TAP++ P P
Sbjct: 2665 SVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEP 2702
Score = 47.4 bits (111), Expect = 5e-05
Identities = 96/391 (24%), Positives = 140/391 (35%), Gaps = 54/391 (13%)
Query: 187 PPKSV---PVCESQKLAPVPSPEP---QKPA---PVSPESVKATLSNPKPQKQSHFPETL 237
PP SV P+ E S E +KPA P SV + + P+P +S +
Sbjct: 2343 PPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDIS 2402
Query: 238 GPPSASSPESPVLAASPEPWGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVS 297
P P P P P P P P S K + SP + P F AV+
Sbjct: 2403 AQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPL--FDAVT 2460
Query: 298 PEP-----RRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKP-I 351
R V+ PP P+P S PS +P P ++P P P +
Sbjct: 2461 TLETTAVLRSNGLPVTRICTTAPPPVPPKP-SSIPSGLVFTHRPEPSKPPIAPKPVIPQL 2519
Query: 352 PSVSPGPW----KPTPSVSSASWKSSSVSPSSWKSP-PASPESWKSGPPELRKTAPTLSP 406
P+ + P KPT ++S + V+ + +K P P SP S P K++P S
Sbjct: 2520 PTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLS-----PHSNKSSPRFS- 2573
Query: 407 EHWKAVPPVSPELRKPGPPLSPEIRSPAGSPELRKPSGSP--DLWKLSPDQRKTSP-ASL 463
K++ + P P +P S A P GSP DL + P P ++
Sbjct: 2574 ---KSLTETYVVITLPSEPGTP-TDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAV 2629
Query: 464 DFPESQKSSRGGSPDLWKSSFFIEPQKPVFPETRKPGPSGPSESPKAASDIWKPVLSIDT 523
+ P S + +F+I F T PS +P + + + T
Sbjct: 2630 EIPISS-----------EQTFYISGALQTFSATPVTAPSSFQAAPTSVTQF------LTT 2672
Query: 524 EPRKPALFPEPAKTAPPASPEARKRALFPEP 554
E K + TAP + + PEP
Sbjct: 2673 EVSKTEV-SATRSTAPSVGLSSISITIPPEP 2702
Score = 35.4 bits (80), Expect = 0.21
Identities = 42/211 (19%), Positives = 80/211 (37%), Gaps = 35/211 (16%)
Query: 103 TDPVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKPTPL---------TP 153
T+ K+ PL + +S +++ +S++T+ +G++ +P P
Sbjct: 3502 TEADKTKPLSK-----VSSIAVQTVAEISVQTEPVGTIRTPSIRARVDAKVEIIKHISAP 3556
Query: 154 LEPQKPGSV-----VSPELQTPLPSPEPSKPASVSSPEP-----PKSVPVCESQKLAPVP 203
+ K GS+ + Q+P S P P P + + +LAP P
Sbjct: 3557 EKTYKGGSLGCQTEADSDTQSPQYLSATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSP 3616
Query: 204 SPEPQKP-APVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPA 262
P+ +P+SP S L + + P+ + P P+ + P
Sbjct: 3617 PKSPKVLYSPISPLSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKV----------PP 3666
Query: 263 ASPESRKSARTTSPEPRKPSPSESPEPWKPF 293
ASP++ K + + +P+ SP+ PF
Sbjct: 3667 ASPKTAKMMQRSMSDPKPLSPTADESSRAPF 3697
Score = 30.0 bits (66), Expect = 9.0
Identities = 43/174 (24%), Positives = 56/174 (32%), Gaps = 20/174 (11%)
Query: 139 SVLSPESPKPTPLTPLEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQK 198
S SP K P TPLE + + PSP P P + SP P S
Sbjct: 3582 SATSPPKDKKRP-TPLEIGYSSHLRADSTVQLAPSP-PKSPKVLYSPISPLSPGKALESA 3639
Query: 199 LAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWG 258
P P P + PQK H PP++ + + +P
Sbjct: 3640 FVPYEKPLPD---------------DISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKP 3684
Query: 259 PSPAASPESRKSARTTSPEPRKPSPS-ESPEPWKPFPAVSPEPRRPAPAVSPGS 311
SP A SR + T K S + S K P P P +S G+
Sbjct: 3685 LSPTADESSRAPFQYTEGYTTKGSQTMTSSGAQKKVKRTLPNP--PPEEISTGT 3736
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 98.6 bits (244), Expect = 2e-20
Identities = 128/430 (29%), Positives = 168/430 (39%), Gaps = 57/430 (13%)
Query: 105 PVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLS-PESPKPTPLTPLEPQKPGSVV 163
P S P P Q +P A P S S+ + L + S SP +PL PQ P ++
Sbjct: 343 PSPSAP-PSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALA 401
Query: 164 SPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQKPAPVSPESVKATLS 223
P LQ P P PP S P L+P+ +P PQ P ++ ++A S
Sbjct: 402 LPPLQAP--------------PSPPASPP------LSPLATPSPQAPNALAVHLLQAPFS 441
Query: 224 NP-KPQKQSHFPETLGPP---SASSPES--PVLAASPEPWGPSPAASPESRKSARTTSPE 277
P P Q+ F PP SA+ P P LAA P PSP ASP SA +P
Sbjct: 442 PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA---TPP 498
Query: 278 PRKPSPSESPEPWKPFPAVSPEPRRP-APAVSPGSWKPGPPGS-PRPWKSNPSASSGPWK 335
P+ P P +P P P P+ P A A P P PP S P +PSAS
Sbjct: 499 PQAPPPLAAP----PLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSP 554
Query: 336 PAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPPASPESWKSGPP 395
A P P P P+ V P P P A + + P + S P + GPP
Sbjct: 555 LATPPPQAPPVLAAPLLQVPPSP--PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP 612
Query: 396 ELRKTAP--TLS-PE---HWKAVPPVSPELRKPGPPLSPEIRSPAG-SPELRKPSGSPDL 448
+P TLS P+ H + ELR G PE + A P+ + P
Sbjct: 613 PPPSRSPSSTLSGPDLAGHSSSATSTPEELR--GYDSGPEGGAAASPPPDAELAACHPAA 670
Query: 449 WKLSPDQ----RKTSPASLDFPESQKSSRGGSPDLWKSSFFIEPQKPVFPE--TRKPGPS 502
W P R A L +P ++ GS D + + E + P PGPS
Sbjct: 671 WSRGPAPPLAFRGAPGAPLPWP---PATGPGSADGLCTIYETEGPESATPAPGALDPGPS 727
Query: 503 GPSESPKAAS 512
+ KAA+
Sbjct: 728 PGTSGGKAAA 737
Score = 93.2 bits (230), Expect = 9e-19
Identities = 120/461 (26%), Positives = 165/461 (35%), Gaps = 47/461 (10%)
Query: 86 ASPDKWNDKPKNQLNKETDPVKSPPLPEHQKIPCNSA---EPKSIPALSMETQKLGSVLS 142
A P + P+ ++ ++ + P P ++ P P S S T S
Sbjct: 196 ARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARS 255
Query: 143 PESPKPTPLTPLEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPV 202
S + TP P P +P L+ P +P P K A+ P P+ S P
Sbjct: 256 GPSARGTPRAPAHPSQPKPKGLQALRPPQVTP-PRKDAA------PALGPLSSSPLATPS 308
Query: 203 PSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPA 262
PS Q AP ++ AT + Q P L PPS S+P P L P P P+
Sbjct: 309 PSAALQSQAP---PTLPATPHSSSLTCQLATPLPLAPPSPSAP--PSLQTLPSPPATPPS 363
Query: 263 ASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRP 322
+ S S + PSP SP A P PA A+ P P PP SP
Sbjct: 364 QATTSLGSPTLQATHSFLPSPPLSP------LATPPPQAPPALALPPLQAPPSPPASP-- 415
Query: 323 WKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVS-PGPWKP--TPSVSSASWKSSSVSPSS 379
+P A+ P P A + P+ P PS P+ P +P VS ++ S PS
Sbjct: 416 -PLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSL 474
Query: 380 WKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPELRKPGPPLSPEIRSPAGSPEL 439
P P S + PP P A PP+ +L KP P P + +P
Sbjct: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL--QLAKPPPQAPPALATPPLQALP 532
Query: 440 RKPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGSPDLWKSSFFIEPQKPVFP---ET 496
P+ P SP ASL P L + P P P
Sbjct: 533 SPPASFPGQAPFSPS------ASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP 586
Query: 497 RKPGPSGPSESPKAASDIWKPVLSIDTEPRKPALFPEPAKT 537
R+P GP S + P L++ P P P P+++
Sbjct: 587 RRPPTPGPDTS------VSGPRLTLALAPGPP---PPPSRS 618
Score = 79.3 bits (194), Expect = 1e-14
Identities = 138/545 (25%), Positives = 187/545 (34%), Gaps = 124/545 (22%)
Query: 143 PESPKPTPLTPLEP------------------QKPGSVVSPELQTPLPSPEPSKPASVSS 184
P SP+P P P+ P ++ G + + P P++ A SS
Sbjct: 30 PGSPRPPP--PVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSS 87
Query: 185 PEPPKSVPVCESQKLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHF----PETLGPP 240
P P + AP + P PVS + + P P Q ET+
Sbjct: 88 RNPASRPPASGRGERAP--PAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARG 145
Query: 241 SAS-SPESPVLAAS-------PEPWGPSPAASPESRKSARTTSPEPRKPSPSESPEP--- 289
A+ +P+ L+A P P PSPA + SR +A T PR P+PS P P
Sbjct: 146 KATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSR-AAGTEVGLPR-PAPSARPRPPTE 203
Query: 290 --------------WKPFPAVSPEP------RRPA---------PAVSPGSWKPGPPGSP 320
+P PA P +RPA P SP P G+P
Sbjct: 204 GPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTP 263
Query: 321 R----PWKSNPSASSG--------PWKPAKPA-------PSVSPGPWKPIPSVSPGPWKP 361
R P + P P K A PA P +P P + S +P
Sbjct: 264 RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPA 323
Query: 362 TPSVSSASWK----------SSSVSPS--SWKSPPASPESWKS---GPPELRKT-----A 401
TP SS + + S S PS + SPPA+P S + G P L+ T +
Sbjct: 324 TPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPS 383
Query: 402 PTLSPEHWKAVPP--------VSPELRKPGPPLSPEIRSPAGSPELRKPSGSPDLWKLSP 453
P LSP A PP + P P PP SP + SP +P + P+ +P
Sbjct: 384 PPLSP---LATPPPQAPPALALPPLQAPPSPPASPPL-SPLATPSPQAPNALAVHLLQAP 439
Query: 454 DQRKTSP---ASLDFPESQKSSRGGSPDLWKSSFFIEPQKPVFPETRKPGPSGPSESPKA 510
SP A P S S +P P V P P PS +P
Sbjct: 440 FSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP 499
Query: 511 ASDIWKPVLSIDTEPRKPALFPEPAKTAPPASPEARKRALFPEPRKHALFPELPKSALFS 570
+ P+ + + KP PA PP A FP + LP S L +
Sbjct: 500 QAP--PPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLAT 557
Query: 571 ESQKA 575
+A
Sbjct: 558 PPPQA 562
Score = 65.9 bits (159), Expect = 1e-10
Identities = 105/395 (26%), Positives = 152/395 (38%), Gaps = 68/395 (17%)
Query: 199 LAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWG 258
L P P P+ P PV+P +++ + ++ G A+ PES A G
Sbjct: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
Query: 259 PS---PAASP------ESRKSARTTSPEPRKPSPSESPEPWKPFP------AVSPE---- 299
S PA+ P E A+ TSP P SP + +P P +S E
Sbjct: 85 TSSRNPASRPPASGRGERAPPAKNTSPGP-VSSPGRASGTTRPGPLGQKGLRISAEETVA 143
Query: 300 -------PRRPAPAVSPGSWKPGP-PGSPRPWKSNPSASSGPWKP-AKPAPSVSP----- 345
P+R A + GP PG+P P + S ++G +PAPS P
Sbjct: 144 RGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE 203
Query: 346 GPWKPIPSVS------PGP-WKPTPSVSSASWKSSSVSPSSWKSPPASPESWKSGP---- 394
GP K + S S P P + PS + +S S SS +P +SP +SGP
Sbjct: 204 GPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA--RSGPSARG 261
Query: 395 -PELRKTAPTLSPEHWKAV--PPVSPELRKPGPPLSPEIRSPAGSPELRKPSGSPDLWKL 451
P P+ +A+ P V+P + P L P SP L PS S L
Sbjct: 262 TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP-----LATPSPSAALQSQ 316
Query: 452 SPDQRKTSPASLDFPESQKSSRGGSPDLWKSSFFIEPQKPVFPETRKPGPSGPSESP-KA 510
+P +P S S + + +P + P P P + + PS P+ P +A
Sbjct: 317 APPTLPATPHS-----SSLTCQLATP------LPLAPPSPSAPPSLQTLPSPPATPPSQA 365
Query: 511 ASDIWKPVLSIDTEPRKPALFPEPAKTAPPASPEA 545
+ + P L T P+ P T PP +P A
Sbjct: 366 TTSLGSPTLQA-THSFLPSPPLSPLATPPPQAPPA 399
Score = 61.2 bits (147), Expect = 4e-09
Identities = 81/324 (25%), Positives = 113/324 (34%), Gaps = 75/324 (23%)
Query: 85 HASPDKWNDKPKNQLNKETDPVKSPPL-----PEHQKIPCNSAEPKSIPALSMETQKLGS 139
H ++ P + P SPP+ P Q P +A P +P + +
Sbjct: 434 HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 493
Query: 140 VLSPESPKPTPLT--PLEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQ 197
+P P PL PL+ KP P L TP PS PAS P S
Sbjct: 494 SATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP---FSPSASL 550
Query: 198 KLAPVPSPEPQKPAPVSPESVKATLSNP-KPQKQS-HFPETLGPPSASSPESPVLAASPE 255
++P+ +P PQ P ++ ++ S P P Q+ P T GP ++ S LA +P
Sbjct: 551 PMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG 610
Query: 256 PWGPSPAASPES---------RKSARTTSPEP---------------------------- 278
P P P+ SP S S+ T++PE
Sbjct: 611 P-PPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPA 669
Query: 279 ---RKPSPS-------ESPEPWKP-------------FPAVSPEPRRPAP-AVSPGSWKP 314
R P+P +P PW P + PE PAP A+ PG P
Sbjct: 670 AWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGP-SP 728
Query: 315 GPPGSPRPWKSNPSASSGPWKPAK 338
G G + ASS K A+
Sbjct: 729 GTSGGKAAAGAGAGASSRSPKQAR 752
Score = 35.8 bits (81), Expect = 0.16
Identities = 66/276 (23%), Positives = 97/276 (35%), Gaps = 36/276 (13%)
Query: 301 RRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWK 360
R PA A +PG P PPGSPRP P + + A +V P G
Sbjct: 15 RTPA-ARAPGLLTPRPPGSPRP---PPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATI 70
Query: 361 PTPSVSSASWKSSSVSPSSWKS-PPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPEL 419
P + + +S+ S + S PPAS ++ P + P SP P L
Sbjct: 71 PESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGP-L 129
Query: 420 RKPGPPLSPEIRSPAG-----------SPELRKPSGSPDLWKLSPDQRKTSPAS---LDF 465
+ G +S E G S R+ + P SP + S A+ +
Sbjct: 130 GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGL 189
Query: 466 PESQKSSRGGSPDLWKSSFFIEPQKPVFP----ETRKPGPSGPSESPKAASDIWKPVLSI 521
P S+R P P+K V T +P P+ P A + +P
Sbjct: 190 PRPAPSARPRPPT-------EGPRKSVSSASEHSTTEPSPAA-RRRPSAGGGLQRPASRS 241
Query: 522 DTEPRKPALFPEPAKTAPPA--SPEARKRALFPEPR 555
+ P PA++ P A +P A P+P+
Sbjct: 242 LSSSATP--LSSPARSGPSARGTPRAPAHPSQPKPK 275
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 98.6 bits (244), Expect = 2e-20
Identities = 142/581 (24%), Positives = 210/581 (36%), Gaps = 78/581 (13%)
Query: 104 DPVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKP-TPLTPLEPQKPGSV 162
+ KSPP E S E ++ + E + SPE + +P P+K S
Sbjct: 499 EETKSPPAEE-----AASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSP 553
Query: 163 VSPELQTPLPSPEPSK-----PASVSSPEPPKSVPVCESQKLAPVPSPEPQKPAPVSPES 217
E ++P + P K PA V SPE KS E++ A SPE K SP
Sbjct: 554 AKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAK----SP-- 607
Query: 218 VKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPAASPESRKSARTTSPE 277
VK +P K E P SPE E P A SPE ++ SPE
Sbjct: 608 VKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEA---KSPE 664
Query: 278 PRK-PSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKP 336
K P +E+ P K V E + P A SP + +P + P K
Sbjct: 665 KAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSP----------VKEEAKSPEKAKSPVKE 714
Query: 337 AKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPP-------ASPES 389
+P + P K TP + + K + SP KSP SPE+
Sbjct: 715 EAKSPEKAKSPVKEEAK--------TPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEA 766
Query: 390 WKSGPPELRKTAPTLSPEHWKAVPPVSPELRKPGPPLSPEIRSPAGSPELRKPSGSPDLW 449
E R A PE KA PV E++ P SP ++ A +PE P
Sbjct: 767 KTPAKEEARSPADKF-PE--KAKSPVKEEVKSPEKAKSP-LKEDAKAPEKEIPKKEE--- 819
Query: 450 KLSPDQRKTSPASLDFPESQKSSRGGSPDLWKSSFFIEPQKPVFPETRKPGPSGPSESPK 509
SP + + P + E K + E + P P+T + S E+PK
Sbjct: 820 VKSPVKEEEKPQEVKVKEPPKKAE-------------EEKAPATPKTEEKKDSKKEEAPK 866
Query: 510 AASDIWKPVLSIDTEPRKPALFPEPAKTAPPASPEARKRALFPEPRKHALFPELPKSALF 569
+ KP + E ++PA+ EA + P P K A P +
Sbjct: 867 KEAP--KPKVE---EKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEA--PAKVEVKED 919
Query: 570 SESQKAVELGDELQIDAIDDQKCDILVQEELLASPKKLLEDTLFPSSKKLKKDNQESSDA 629
++ ++ E+ + DA + ++E K E+ +K K + + D
Sbjct: 920 AKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDD 979
Query: 630 ELSSSEYIKTDLDAMDIKGQESSSDQEQVDVESIDFSKENK 670
+ S E K + E SS +Q D + + + E+K
Sbjct: 980 KTLSKEPSKPKAEK-----AEKSSSTDQKDSKPPEKATEDK 1015
Score = 83.2 bits (204), Expect = 9e-16
Identities = 109/444 (24%), Positives = 160/444 (36%), Gaps = 62/444 (13%)
Query: 83 SKHASPDKWNDKPKNQLNKETDPVKSPPLPEHQKIPC-----NSAEPKSIPALSMETQKL 137
+K + K +K K+ +E PE K P + AE KS + E +
Sbjct: 572 AKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKS--PVKEEAKSP 629
Query: 138 GSVLSPESPK-PTPLTPLEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCES 196
V SPE K PT P+K S E ++P + P K A SPE KS PV ++
Sbjct: 630 AEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVK-AEAKSPEKAKS-PV-KA 686
Query: 197 QKLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASP-- 254
+ +P + P K SPE K+ + ++++ PE P ++P A SP
Sbjct: 687 EAKSPEKAKSPVKEEAKSPEKAKSPV-----KEEAKSPEKAKSPVKEEAKTPEKAKSPVK 741
Query: 255 -EPWGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKPFP-----AVSPEPRRPAPAVS 308
E P A SPE K+ SPE + P+ E+ P FP V E + P A S
Sbjct: 742 EEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKS 801
Query: 309 PGSWKPGPPGSPRPWKSN-------------------PSASSGPWKPAKP--------AP 341
P P P K P + PA P
Sbjct: 802 PLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKK 861
Query: 342 SVSPGPWKPIPSV----SPGPWKPTPSVSSASWKSSSVS---PSSWKSPPASPESWKSGP 394
+P P P V P KP S A + + P+ K PA E +
Sbjct: 862 EEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAK 921
Query: 395 PELRKTAPTLSPEHWKAVPPVSPELRKPGPPLSPEIRSPAGSPELRKPSGSPDLWKLSPD 454
P+ + P+ KA P P +K P + + + +KP P + +
Sbjct: 922 PKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTK----EEKAKKPEEKPKTEAKAKE 977
Query: 455 QRKTSPASLDFPESQKSSRGGSPD 478
KT P+++K+ + S D
Sbjct: 978 DDKTLSKEPSKPKAEKAEKSSSTD 1001
Score = 53.9 bits (128), Expect = 6e-07
Identities = 76/335 (22%), Positives = 118/335 (35%), Gaps = 24/335 (7%)
Query: 81 ITSKHASPDKWNDKPKNQLNKETDPVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSV 140
+ ++ SP+K K + K + KSP + E K P + P A + E K S
Sbjct: 684 VKAEAKSPEKAKSPVKEEA-KSPEKAKSP-VKEEAKSPEKAKSPVKEEAKTPEKAK--SP 739
Query: 141 LSPESPKPTPLTPLEPQKPGSVVSPELQTPLPS---------PEPSK---PASVSSPEPP 188
+ E+ P E K V SPE +TP PE +K V SPE
Sbjct: 740 VKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKA 799
Query: 189 KSVPVCESQKLAPVPSPEPQK-PAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPES 247
KS P+ E K P+ ++ +PV E + +P K++ + P +
Sbjct: 800 KS-PLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKD 858
Query: 248 PVLAASPEPWGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPAPAV 307
+P+ P P E ++ A E + + E E K P P + APA
Sbjct: 859 SKKEEAPKKEAPKPKVE-EKKEPAVEKPKESKVEAKKEEAEDKKKVPT----PEKEAPAK 913
Query: 308 SPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSS 367
P K P + +P+KPA P K +
Sbjct: 914 VEVKEDAKPKEKTEVAKKEPDDAKAK-EPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTE 972
Query: 368 ASWKSSSVSPSSWKSPPASPESWKSGPPELRKTAP 402
A K + S S P + ++ KS + + + P
Sbjct: 973 AKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKP 1007
>gi|40807475 PML-RARA regulated adaptor molecule 1 [Homo sapiens]
Length = 669
Score = 97.8 bits (242), Expect = 4e-20
Identities = 145/521 (27%), Positives = 200/521 (38%), Gaps = 89/521 (17%)
Query: 88 PDKWNDKPKNQLNKE-TDPVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLG-SVLSPES 145
P + D PK E TD K PP PE +P P + L + KL S LS +
Sbjct: 73 PPEVTDLPKKPPPPEVTDLPKKPPPPEVTDLP-KKPPPPEVTDLPKKPSKLELSDLSKKF 131
Query: 146 PK----PTPLTPLEPQKPGSVVSPELQTP-LPSPEPSKPASVSSPEPPKSVPVCESQKLA 200
P+ P P PL+P+ + + L P P+ +P +P +S P P S P K
Sbjct: 132 PQLGATPFPRKPLQPEVGEAPLKASLPEPGAPARKPLQPDELSHPARPPSEP-----KSG 186
Query: 201 PVP----SPEPQKPAPVSPESVKATLSNPKPQKQSHF---------PETLGPPSASSPES 247
P PE + P SP+ +T PK Q F P+ G P S P+
Sbjct: 187 AFPRKLWQPEAGEATPRSPQPELSTF--PKKPAQPEFNVYPKKPPQPQVGGLPKKSVPQP 244
Query: 248 PVLAASPEPWGPSPAASPESRKSA--RTTSPEPRKPSPSESPEP-------WKPFPAVSP 298
A+ P ++ P+ SA + S P P + P+P P VS
Sbjct: 245 EFSEAAQTPLWKPQSSEPKRDSSAFPKKASQPPLSDFPKKPPQPELGDLTRTSSEPEVSV 304
Query: 299 EPRRPAPAVSPG-SWKPGPP---GSPRPWKSNPSASSGPWKPAKPAPSVSPGPW-KPIPS 353
P+RP PA S KP P G PR S P +S P K +P P + +P PS
Sbjct: 305 LPKRPRPAEFKALSKKPPQPELGGLPRT-SSEPEFNSLPRKLLQPERRGPPRKFSQPEPS 363
Query: 354 V-----------SPGPWKPTPSVSSASWKSSSVSPSSWKSP-PASPESWKSGPPELRKTA 401
P KP P SSAS S + + + S P SP +G P R
Sbjct: 364 AVLKRHPQPEFFGDLPRKP-PLPSSASESSLPAAVAGFSSRHPLSPGFGAAGTPRWRSGG 422
Query: 402 PTLSPEHWKAVPPVSPELRKPGPPLSPEIRSPAGSP---------ELRKPSGSPDLWKLS 452
S + P P R+P PP S PA P R+PS + S
Sbjct: 423 LVHSGGARPGLRPSHPPRRRPLPPASSLGHPPAKPPLPPGPVDMQSFRRPSAA------S 476
Query: 453 PDQRKT-SPASLDFPESQKSSRGGSPDLWKSSFFIEPQKPVFPETRKPGPSGPSESPKAA 511
D R+T S A L F + Q ++++ +EP+ + P P G E+P
Sbjct: 477 IDLRRTRSAAGLHFQDRQPEDIPVPDEIYELYDDVEPR-----DDSSPSPKGRDEAPSVQ 531
Query: 512 SDIWKPVLSIDTEPRKPAL----FPEPAKTAPPASPEARKR 548
+P P+ PAL P+P + PP P+ K+
Sbjct: 532 QAARRP-------PQDPALRKEKDPQP-QQLPPMDPKLLKQ 564
Score = 73.2 bits (178), Expect = 9e-13
Identities = 112/420 (26%), Positives = 145/420 (34%), Gaps = 63/420 (15%)
Query: 103 TDPVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKPTPLTPLEPQKPGSV 162
+D K PP PE K+ + S P LS E PK PL
Sbjct: 30 SDLPKKPPKPEFGKL-----KKFSQPELS------------EHPKKAPLPEF------GA 66
Query: 163 VSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQKPAPVSPESVKATL 222
VS + P + P KP + PK P E L P P P P ++ +
Sbjct: 67 VSLKPPPPEVTDLPKKPPPPEVTDLPKKPPPPEVTDLPKKPPPPEVTDLPKKPSKLELSD 126
Query: 223 SNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPAASPESRKSARTTSPEPRKPS 282
+ K + P P E+P+ A+ PEP +PA P + P +P
Sbjct: 127 LSKKFPQLGATPFPRKPLQPEVGEAPLKASLPEP--GAPARKPLQPDELSHPARPPSEPK 184
Query: 283 PSESPEP-WKPFPAVSPEPRRPAPAVSPGSWKPGPPG-SPRPWKSNPSASSGPWKPAKPA 340
P W+P A PR P P +S KP P + P K G K + P
Sbjct: 185 SGAFPRKLWQP-EAGEATPRSPQPELSTFPKKPAQPEFNVYPKKPPQPQVGGLPKKSVPQ 243
Query: 341 PSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPPASPESWKSGPPELRKT 400
P S P+ WKP SS + SS P PP S K PEL
Sbjct: 244 PEFSEAAQTPL-------WKPQ---SSEPKRDSSAFPKKASQPPLSDFPKKPPQPELGDL 293
Query: 401 APTLSPEHWKAVPPVSPELRKPGPPLSPEIRSPAGSPE---LRKPSGSPDL----WKLSP 453
T S P VS ++P P + PE L + S P+ KL
Sbjct: 294 TRTSSE------PEVSVLPKRPRPAEFKALSKKPPQPELGGLPRTSSEPEFNSLPRKLLQ 347
Query: 454 DQRKTSPASLDFPE-SQKSSRGGSPDLWKSSFFIEPQKPVFPETRKPGPSGPSESPKAAS 512
+R+ P PE S R P+ F P+KP P PS SES A+
Sbjct: 348 PERRGPPRKFSQPEPSAVLKRHPQPEF----FGDLPRKP-------PLPSSASESSLPAA 396
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 96.7 bits (239), Expect = 8e-20
Identities = 123/452 (27%), Positives = 171/452 (37%), Gaps = 78/452 (17%)
Query: 111 LPEHQKIPCNSAEPKS--------IPALSMETQKLGSV----LSPESPKPTPLTPLEPQK 158
+P H K+P + P S PAL+ G V SP+SP PTP T L P +
Sbjct: 660 IPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSP-PTPQTTLTPLQ 718
Query: 159 PGSVVSPELQTPLPSPEPS---KPASVSSPEPPKSVPVCESQKLAPVPSPEPQKPAPVSP 215
V+S + Q+P PSP PS P PE P P+ P P P +P
Sbjct: 719 ESPVISKD-QSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAP 777
Query: 216 ESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPAASPESRKSARTTS 275
E ++++ P +++ F ASPEP GPS + S +A ++S
Sbjct: 778 EEQDLSMADFPPPEEAFFS----------------VASPEPAGPSGSPELVSSPAASSSS 821
Query: 276 PEPRKPSPSESPEPWKPFPAVSPEPRRPAPAVS-PGSWKPGPPGSPRPWKSNPSASSGPW 334
+ P SP+P P P PAPA S PG P P S GP
Sbjct: 822 ATALQIQPPGSPDP-------PPAPPAPAPASSAPGHVAKLPQKEP----VGCSKGGGPP 870
Query: 335 KPAKPAPSVSPGPWKPI--PSVSPGPWKPTPSVS-SASWKSSSVSPSSWKSPPASPESWK 391
+ AP V+P + + SV PTP++ SA K + S SP +P S
Sbjct: 871 REDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGL 930
Query: 392 SGPPELRKTAPTLSPEHWKAVPPVSPELRKPGPPLSPEIRSPAGSPELRKPSGSPDLWKL 451
L K + E + P P +P PP +SPA + GS L
Sbjct: 931 HAAVRL-KACSLAASEGLSSAQPNGPPEAEPRPP-----QSPASTASFIFSKGSRKL--- 981
Query: 452 SPDQRKTSPASLDFPESQKSSRGGSPDLWKSSFFIEPQKPVFPETRKPGPSGPSESPKAA 511
L+ P S ++ +L I Q+P P P +SPKA
Sbjct: 982 ----------QLERPVSPETQADLQRNLVAELRSISEQRP---------PQAPKKSPKAP 1022
Query: 512 SDI-WKPVLSIDTEPRKPALFPEPAKTAPPAS 542
+ KP + + P P+ TAPP +
Sbjct: 1023 PPVARKPSVGV-PPPASPSYPRAEPLTAPPTN 1053
Score = 72.0 bits (175), Expect = 2e-12
Identities = 97/349 (27%), Positives = 129/349 (36%), Gaps = 50/349 (14%)
Query: 112 PEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKPTPLTPLEPQKPGSVVSPELQTPL 171
P + P S E P+ +Q L P+ P +P + Q P PE T L
Sbjct: 564 PGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPP----KPERVTSL 619
Query: 172 PSPEPSKPASV----SSPEPPKSVPVCESQKLAP-----VPSPEPQKPAPVSPESVKATL 222
SP S +S+ SS P Q L P V P P+ PAP SP K
Sbjct: 620 RSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRS 679
Query: 223 SNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPAASP--ESRKSARTTSPEPRK 280
NP P P P S A+ P P +P ES ++ SP P
Sbjct: 680 PNPAA------PALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSP 733
Query: 281 PSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKP------GPPGSPRPWKSNPSASSGPW 334
P P P P PE AP+ S + +P PP P P + + S + P
Sbjct: 734 PPSYHPPPP----PTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFP- 788
Query: 335 KPAKPAPSVSPGPWKPIPSVSPGPWKP--TPSVSSASWKSSSVSPSSWKSPPASPESWKS 392
P + SV+ SP P P +P + S+ SSS + + PP SP+
Sbjct: 789 PPEEAFFSVA----------SPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDP--- 835
Query: 393 GPPELRKTAPTLS-PEHWKAVPPVSP-ELRKPGPPLSPEIRSPAGSPEL 439
PP AP S P H +P P K G P ++ +P +P L
Sbjct: 836 -PPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSL 883
Score = 63.2 bits (152), Expect = 1e-09
Identities = 112/422 (26%), Positives = 147/422 (34%), Gaps = 43/422 (10%)
Query: 158 KPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQKPAPVSPES 217
K GS PE T S P P S P E+ + S VS
Sbjct: 435 KGGSEGQPESSTASNSVVPP-PQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRK 493
Query: 218 VKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPAASPESRKSARTTSPE 277
+K P P +++H G LA P G P PE ++ + P
Sbjct: 494 LKRP---PPPPRRTHSLHQRG-----------LAVPDGPLGLPP--KPERKQQPQLPRPP 537
Query: 278 PRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPA 337
S P P PA S P +SPG + P R + SS P
Sbjct: 538 TTGGSEGAGAAPCPPNPANSW-----VPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPT 592
Query: 338 KPAPSVSPGPWKPIPSVSPGPWKPTPSVS-SASWKSSSVSPSSWKSPPASPESWKSGPPE 396
P ++ P P + P P + T S AS SS S S S PA + +SGP
Sbjct: 593 LPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSD--RSGPQI 650
Query: 397 LRKTAPT-LSPEHWKAVPPVSPELRKPGP--PLSPEIRSPAGSPELRKPSGSPDLWKLSP 453
L + P H K P SP KP P +P + +PA P P + D SP
Sbjct: 651 LTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVP---GPVSTTDASPQSP 707
Query: 454 DQRKTSPASLDFPESQKSSRGGSPDLWKSSFFIEPQKPVFPETRKPGPSGPSESPKAASD 513
+T+ L ES S+ SP + P P T+K P E+P A+
Sbjct: 708 PTPQTTLTPLQ--ESPVISKDQSPPPSPPPSYHPPP----PPTKK--PEVVVEAPSASET 759
Query: 514 IWKPVLSIDTEPRKPALFPEPAKTAP---PASPEARKRALFPEPRKHALFPELPKSALFS 570
+P+ + P P PE + P EA PEP + PEL S S
Sbjct: 760 AEEPLQDPNWPPPPPPA-PEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAAS 818
Query: 571 ES 572
S
Sbjct: 819 SS 820
Score = 56.6 bits (135), Expect = 9e-08
Identities = 96/403 (23%), Positives = 135/403 (33%), Gaps = 90/403 (22%)
Query: 99 LNKETDPVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKPTPLTPL-EPQ 157
++K+ P SPP H P T+K V+ S T PL +P
Sbjct: 723 ISKDQSPPPSPPPSYHPPPP--------------PTKKPEVVVEAPSASETAEEPLQDPN 768
Query: 158 KPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQKPAPVSPES 217
P P P+PE + P P + V SPEP P+ SPE
Sbjct: 769 WP--------PPPPPAPEEQDLSMADFPPP--------EEAFFSVASPEPAGPSG-SPEL 811
Query: 218 VKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPAASPESRKSARTTSPE 277
V S+P S + PP SP+ P P P P+PA+S A+ E
Sbjct: 812 V----SSPAASSSSATALQIQPP--GSPDPP-----PAPPAPAPASSAPGH-VAKLPQKE 859
Query: 278 PRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWK------PGPPGSPRPWKSNPSASS 331
P S P P AP V+P + G PG P+ +
Sbjct: 860 PVGCSKGGGP----------PREDVGAPLVTPSLLQMVRLRSVGAPGGA------PTPAL 903
Query: 332 GPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPPASPESWK 391
GP P KP G P+P+ S G + + S +S + PP +
Sbjct: 904 GPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPP 963
Query: 392 SGPPELRKTAPTLSPEHWKAVPPVSPE---------------LRKPGPPLSPEIRSPAGS 436
P + + PVSPE + + PP +P+ A
Sbjct: 964 QSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPP 1023
Query: 437 PELRKPS------GSPDLWKLSPDQRKTSPASLDFPESQKSSR 473
P RKPS SP + P T+P + P +Q ++
Sbjct: 1024 PVARKPSVGVPPPASPSYPRAEP---LTAPPTNGLPHTQDRTK 1063
Score = 50.8 bits (120), Expect = 5e-06
Identities = 78/328 (23%), Positives = 113/328 (34%), Gaps = 50/328 (15%)
Query: 260 SPAASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGS 319
SPA+ + + +SP+PR PS S + W + VS GS GS
Sbjct: 386 SPASVRSLGRFSSVSSPQPRSRHPSSSSDTWS-------HSQSSDTIVSDGSTLSSKGGS 438
Query: 320 PRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVSPSS 379
+S+ +++S P P G P + SS SVS
Sbjct: 439 EGQPESSTASNS-----VVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRK 493
Query: 380 WKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPELRKPGPPLSPEIRSPAGSPEL 439
K PP P S L + + P+ +PP ++P P P G+
Sbjct: 494 LKRPPPPPRRTHS----LHQRGLAV-PDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAA 548
Query: 440 RKPSGSPDLW--KLSPDQRKTSPASLD---FPESQKSSRGGSPDLWKSSFFIEPQKPVFP 494
P + W LSP + P S + P S SS+ G+P L P P
Sbjct: 549 PCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKA 608
Query: 495 ETRKP----------------------GPSGPSESPKAASDIWKPV---LSIDTEPRKPA 529
+ KP S P+ S ++ I P+ I P+ PA
Sbjct: 609 QPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPA 668
Query: 530 LF-PEPAK--TAPPASPEARKRALFPEP 554
F P P+K + PA+P A+ P P
Sbjct: 669 PFSPPPSKPRSPNPAAPALAAPAVVPGP 696
>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
Length = 1573
Score = 95.5 bits (236), Expect = 2e-19
Identities = 120/461 (26%), Positives = 171/461 (37%), Gaps = 86/461 (18%)
Query: 105 PVKSPPLPEHQKIPCNSAEPKSIP-----ALSMETQKLGSVLSPESPKPTPLTPLEPQKP 159
P SPP P+ P + P I ALS + L+PE P PTPL L +
Sbjct: 1045 PDTSPPTPD----PASRTNPDLILTSPDFALSTPDSSVVPALTPE-PSPTPLPTLPKELT 1099
Query: 160 GSVVSPELQTPLPSPEPSKPASVSSPE---PPKSVPVCESQKLAPVPSPEPQKPAPVSPE 216
+P T L P S ++P+ P S V E + +P PSP P P
Sbjct: 1100 SDPSTPSEVTSLSPTSEQVPESDTTPDLDTTPYSSTVSEYSR-SPDPSPSPHPTTTPDPT 1158
Query: 217 SVKATLSNPKPQKQSHFPETLGPPSASSPES-------PVLAASPEPWG--------PSP 261
++ P HFP T P + P + P +P+P+ P P
Sbjct: 1159 MAPDPITTLNPTVTPHFPTTPHPTTTPHPTTITHSTMIPDPTTTPQPFTTITHSTMIPDP 1218
Query: 262 AASPESRKSAR-TTSPEPRKPSPSESPEPWK-------PFPAVSPEP---RRPAPAVSPG 310
+P+ + + TT+P P P+ +P P P P +P+P +P P
Sbjct: 1219 TTTPQPFTTMQPTTTPHSTTPHPTTTPHPTTITHSTMIPDPTTTPQPFTTMQPTTMPHP- 1277
Query: 311 SWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGP-WKPIPSVSPGPWKP----TPSV 365
+ P P +P P + P ++ P P P+ +P P P P+ +P P P TP +
Sbjct: 1278 TTTPHPTTTPHP-TTTPHPTTTPHPTMTPDPTTTPYPTTTPDPTTTPHPTTPDPSSTPVI 1336
Query: 366 SSASWKSSSVSPSSWKSPPASPESWKSGPPELRKTA----------PTLSPEHWKAVPPV 415
++ S +S + S SP +P S P+L TA PTL P P
Sbjct: 1337 TTVSLPTSLGTELS--SPTLAPTVKPSLHPQLTFTAPAPHTSTSQIPTLEPSPALESSPS 1394
Query: 416 SPELRKPGPPLSPEIRSPAGS-------PELRKPSGSPDLWKLSPDQRKTSPA-SLDFPE 467
PLS E P S P P + DL +SPD + A LD P
Sbjct: 1395 RSSTATSMDPLSTEDFKPPRSQSPNLTPPPTHTPHSASDL-TVSPDPLLSPTAHPLDHPP 1453
Query: 468 SQKSSRGGSPDLWKSSFFIEPQKPVFPETRKPGPSGPSESP 508
+ G +P + PGP GP +P
Sbjct: 1454 LDPLTLGPTPG------------------QSPGPHGPCVAP 1476
Score = 71.2 bits (173), Expect = 4e-12
Identities = 130/558 (23%), Positives = 196/558 (35%), Gaps = 129/558 (23%)
Query: 138 GSVLSPESPKP--------TPLTPLEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEP-- 187
G+ SP SP +P P ++P + P PSP PS AS P P
Sbjct: 965 GTTRSPGSPPTLRVHGDTGSPRKPWPERRPPRPAATRTAPPTPSPGPS--ASPGPPGPAL 1022
Query: 188 ---------PKSVPVCESQKLAPVPSPEPQKPAP---------------VSPES--VKAT 221
P S E+ AP SP PA +P+S V A
Sbjct: 1023 TSDSSRELTPHSALTSEATSDAPDTSPPTPDPASRTNPDLILTSPDFALSTPDSSVVPAL 1082
Query: 222 LSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWG---PSPAASP--ESRKSARTTSP 276
P P P+ L S P +P S P P +P ++ + T S
Sbjct: 1083 TPEPSPTPLPTLPKEL----TSDPSTPSEVTSLSPTSEQVPESDTTPDLDTTPYSSTVSE 1138
Query: 277 EPRKPSPSESPEP-WKPFPAVSPE-------------PRRPAPAVSP-------GSWKPG 315
R P PS SP P P P ++P+ P P P +P + P
Sbjct: 1139 YSRSPDPSPSPHPTTTPDPTMAPDPITTLNPTVTPHFPTTPHPTTTPHPTTITHSTMIPD 1198
Query: 316 PPGSPRPWKS--------NPSASSGPWKPAKPA---------PSVSPGPWK-------PI 351
P +P+P+ + +P+ + P+ +P P+ +P P P
Sbjct: 1199 PTTTPQPFTTITHSTMIPDPTTTPQPFTTMQPTTTPHSTTPHPTTTPHPTTITHSTMIPD 1258
Query: 352 PSVSPGPW---KPT--PSVSSASWKSSSVSPSSWKSPPASPESWKSGPPELRKTAPTLSP 406
P+ +P P+ +PT P ++ +++ P++ P +P + P PT +P
Sbjct: 1259 PTTTPQPFTTMQPTTMPHPTTTPHPTTTPHPTTTPHPTTTPHPTMT-PDPTTTPYPTTTP 1317
Query: 407 EHWKAVPPVSPELRKPGPPLSP-------------EIRSPAGSPELRKPSGSPDLWKLSP 453
+ P +P P P +P E+ SP +P + KPS P L +P
Sbjct: 1318 D-----PTTTPHPTTPDPSSTPVITTVSLPTSLGTELSSPTLAPTV-KPSLHPQLTFTAP 1371
Query: 454 DQRKTS---PASLDFPESQKSSRGGSPDLWKSSFFIEPQKPVFPETRKPG-PSGPSESPK 509
++ P P + S S E KP P ++ P P+ +P
Sbjct: 1372 APHTSTSQIPTLEPSPALESSPSRSSTATSMDPLSTEDFKP--PRSQSPNLTPPPTHTPH 1429
Query: 510 AASDIW---KPVLSIDTEP-RKPALFPEPAKTAPPASPEARKRALFPEPRKHALFPELPK 565
+ASD+ P+LS P P L P P SP + P P + E P
Sbjct: 1430 SASDLTVSPDPLLSPTAHPLDHPPLDPLTLGPTPGQSPGPHGPCVAPTPPVRVMACEPP- 1488
Query: 566 SALFSESQKAVELGDELQ 583
AL ++G +LQ
Sbjct: 1489 -ALVELVAAVRDVGGQLQ 1505
Score = 51.2 bits (121), Expect = 4e-06
Identities = 93/398 (23%), Positives = 137/398 (34%), Gaps = 60/398 (15%)
Query: 236 TLGPPSASSPESP----VLAASPEPWGPSPAASPESRKSARTTSPEPRKPSPSESPEPWK 291
TLG + SP SP V + P P P P + RT P PSP S P
Sbjct: 961 TLGAGTTRSPGSPPTLRVHGDTGSPRKPWPERRPPRPAATRTAPP---TPSPGPSASPGP 1017
Query: 292 PFPAVSPEPRR---PAPAVSPGSWKPGP---PGSPRP-WKSNPS--ASSGPWKPAKPAPS 342
P PA++ + R P A++ + P P +P P ++NP +S + + P S
Sbjct: 1018 PGPALTSDSSRELTPHSALTSEATSDAPDTSPPTPDPASRTNPDLILTSPDFALSTPDSS 1077
Query: 343 VSPGPWKPIPSVSPGPWKPTPSVSSASWKS--SSVSPSS--------------------- 379
V P P PS +P P P S S S +S+SP+S
Sbjct: 1078 VVPA-LTPEPSPTPLPTLPKELTSDPSTPSEVTSLSPTSEQVPESDTTPDLDTTPYSSTV 1136
Query: 380 ---WKSPPASPESWKSGPPELRKTAPTLSPEHWKAV-PPVSPEL-RKPGPPLSPEIRSPA 434
+SP SP + P+ PT++P+ + P V+P P P +P +
Sbjct: 1137 SEYSRSPDPSPSPHPTTTPD-----PTMAPDPITTLNPTVTPHFPTTPHPTTTPHPTTIT 1191
Query: 435 GSPELRKPSGSPDLW------KLSPDQRKT-SPASLDFPESQKSSRGGSPDLWKSSFFIE 487
S + P+ +P + + PD T P + P + S P I
Sbjct: 1192 HSTMIPDPTTTPQPFTTITHSTMIPDPTTTPQPFTTMQPTTTPHSTTPHPTTTPHPTTIT 1251
Query: 488 PQKPVFPETRKPGP---SGPSESPKAASDIWKPVLSIDTEPRKPALFPEPAKTAPPASPE 544
+ T P P P+ P + T P P P T P +
Sbjct: 1252 HSTMIPDPTTTPQPFTTMQPTTMPHPTTTPHPTTTPHPTTTPHPTTTPHPTMTPDPTTTP 1311
Query: 545 ARKRALFPEPRKHALFPELPKSALFSESQKAVELGDEL 582
P H P+ + + + LG EL
Sbjct: 1312 YPTTTPDPTTTPHPTTPDPSSTPVITTVSLPTSLGTEL 1349
Score = 33.9 bits (76), Expect = 0.62
Identities = 44/178 (24%), Positives = 68/178 (38%), Gaps = 16/178 (8%)
Query: 132 METQKLGSVLSPESPKPTPLTPLE-PQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKS 190
+ T+ SV + K T P + P+ V+ + P P P P + S +S
Sbjct: 600 LATKPSASVTASVLEKTTTKAPGKMPKSTKKWVTKNAKRPTTQP-PVMPTTKHSRA--QS 656
Query: 191 VPVCESQKLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVL 250
P SQ A + + ++P + E + + + SH TL P + + +
Sbjct: 657 PPDLTSQTTAALTTEASRRP---TSEFTRRPTTEAPQRWTSHTTATLTPQAPRERTTKTM 713
Query: 251 AASPEPWGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPAPAVS 308
A GP S + KS S EP P SPE SP+ P+P+VS
Sbjct: 714 AMLTTQ-GPQEMTSESTIKSIPQASLEPSAEIPEGSPE--------SPKDPAPSPSVS 762
Score = 32.7 bits (73), Expect = 1.4
Identities = 44/189 (23%), Positives = 65/189 (34%), Gaps = 26/189 (13%)
Query: 181 SVSSPEPPKSVPVCESQKLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPP 240
S+S P +P + A +P KP+ SV + P K +
Sbjct: 575 SISDPFSWSWIPGLGRDRDAWLPGELATKPSASVTASVLEKTTTKAPGKMPKSTKKWVTK 634
Query: 241 SASSP--ESPVL-------AASPEPWGPSPAASPESRKSARTTSPEPRKPSPSESPEPWK 291
+A P + PV+ A SP A+ + S R TS R+P+ +E+P+ W
Sbjct: 635 NAKRPTTQPPVMPTTKHSRAQSPPDLTSQTTAALTTEASRRPTSEFTRRPT-TEAPQRWT 693
Query: 292 PFPAVSPEPRRPAPAV----------------SPGSWKPGPPGSPRPWKSNPSASSGPWK 335
+ P+ P S + K P S P P S K
Sbjct: 694 SHTTATLTPQAPRERTTKTMAMLTTQGPQEMTSESTIKSIPQASLEPSAEIPEGSPESPK 753
Query: 336 PAKPAPSVS 344
P+PSVS
Sbjct: 754 DPAPSPSVS 762
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 95.5 bits (236), Expect = 2e-19
Identities = 125/524 (23%), Positives = 196/524 (37%), Gaps = 76/524 (14%)
Query: 90 KWNDKPKNQLNKETDPVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKPT 149
K D KN+ K+ P PP+ + ++ + K + TQ SP+
Sbjct: 158 KVKDNKKNRTKKK--PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAK 215
Query: 150 PLTPLEPQKPGSVVSPEL------QTPLPSPEPSKP---------ASVSSPEPPKSVPVC 194
P+ P P S S E +T + + E + +S + +S+
Sbjct: 216 PINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKT 275
Query: 195 ESQKLAPV------PSPE------------PQKPAPVSP-ESVKATLSNPKPQKQSHFPE 235
++ LAP P+P+ P++P P +P E T P P P
Sbjct: 276 SAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPT 335
Query: 236 TLGPPSASSPESPVLAASPEPWGPSPAASPE-----SRKSARTTSPEP------RKPSPS 284
T P+ ++ +S A P P+P + E ++ A TT+ EP P+
Sbjct: 336 TPKEPAPTTTKS----APTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTP 391
Query: 285 ESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVS 344
+ P P P P+ PAP +P P P P P P+ P P +PAP+
Sbjct: 392 KEPAPTTPKKPAPTTPKEPAP-TTPKEPTPTTPKEPAPTTKEPA----PTTPKEPAPT-- 444
Query: 345 PGPWKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPPASPESWKSGPPELRKTAPTL 404
P KP P+ P PT A + SP++ K P +P + KS P ++ APT
Sbjct: 445 -APKKPAPTTPKEP-APTTPKEPAPTTTKEPSPTTPKEP--APTTTKSAPTTTKEPAPTT 500
Query: 405 SPEHWKAVPPVSPELRKPGPPLSPEIRSPAGSPELRKPSGSPDLWKLSPDQRKTSPASLD 464
+ SP K P +P+ +P +P+ P+ + +P + +
Sbjct: 501 TKSAPTTPKEPSPTTTKEPAPTTPKEPAPT-TPKKPAPTTPKEPAPTTPKEPAPTTTKKP 559
Query: 465 FPESQKSSRGGSPDLWKSSFFIEPQK--PVFPETRKPGPSGPSESPKAASDIWKPVLSID 522
P + K +P K + P+K P PE K P+ P + + P +
Sbjct: 560 APTTPKEPAPTTP---KETAPTTPKKLTPTTPE--KLAPTTPEKPAPTTPEELAPTTPEE 614
Query: 523 TEPRKPALFPEPAKTAP-PASPEARKRALFPEPRKHALFPELPK 565
P P EPA T P A+P K P++ A P PK
Sbjct: 615 PTPTTP---EEPAPTTPKAAAPNTPKEPAPTTPKEPA--PTTPK 653
Score = 93.2 bits (230), Expect = 9e-19
Identities = 114/491 (23%), Positives = 179/491 (36%), Gaps = 50/491 (10%)
Query: 94 KPKNQLNKETDPVK-SPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPK----- 147
KP KE P P P K P + + P ET +P +PK
Sbjct: 534 KPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET-------APTTPKKLTPT 586
Query: 148 -PTPLTPLEPQKPGSVVSPELQTPLP-SPEPSKPASVSSPEPPKSVPVCESQKLAPV--- 202
P L P P+KP EL P P P+ P +P PK+ ++ AP
Sbjct: 587 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE-PAPTTPKAAAPNTPKEPAPTTPK 645
Query: 203 -PSP-EPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPS 260
P+P P++PAP +P+ T PK P TL P+ ++P+ P +P+ P+
Sbjct: 646 EPAPTTPKEPAPTTPKETAPT--TPK----GTAPTTLKEPAPTTPKKP----APKELAPT 695
Query: 261 PAASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPAP-AVSPGSWK---PGP 316
P S P P P + P +P P EP P +P + K P
Sbjct: 696 TTKEP---TSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTT 752
Query: 317 PGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVS 376
P P P + P+ + GP S P P P + P +P P+ ++ +
Sbjct: 753 PKKPAPKELAPTTTKGP----TSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPET 808
Query: 377 PSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPELRKPGPPLSPEIRSPAGS 436
P S ++P + K P + K+ +PE A P P P P ++PA +
Sbjct: 809 PPPTTSEVSTPTTTKE-PTTIHKSPDESTPE-LSAEPTPKALENSPKEPGVPTTKTPAAT 866
Query: 437 -PELRKPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGSPDLWKSSFFIEPQKPVFPE 495
PE+ + + D R T + P+ K + + +S +
Sbjct: 867 KPEMTTTAKDKTTER---DLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTT 923
Query: 496 TRKPGPSGPSESPKAASDIWKPVLSIDTEPRKPALFPEPAKTAPPASPEARKRALFPEPR 555
T+ P + + + V + + +P +TA P +A P+P+
Sbjct: 924 TQDTTPF--KITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQ 981
Query: 556 KHALFPELPKS 566
K P+ P S
Sbjct: 982 KPTKAPKKPTS 992
Score = 62.4 bits (150), Expect = 2e-09
Identities = 103/475 (21%), Positives = 168/475 (35%), Gaps = 80/475 (16%)
Query: 140 VLSPESPKPTPLTPLEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKL 199
V +P SP + P ++ S ++P P + + S E + V E+Q+
Sbjct: 66 VHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQES 125
Query: 200 APVPSP--------------------EPQKPAPVSPESVKATLSNPKPQ----------- 228
+ S E QK V T P P+
Sbjct: 126 SSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGL 185
Query: 229 KQSHFPETLGPPSASSPESPVLAASP-----EPWGPSPAASPESRKSARTTSPEPRKPSP 283
F T P S+ + ++ SP +P P P+ P S +++ TS K +
Sbjct: 186 DNGDFKVT--TPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNS-DTSKETSLTVNKETT 242
Query: 284 SESPEPWKPFPAVSPEPR------RPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPA 337
E+ E S + + + ++ S K P S K P A + PA
Sbjct: 243 VETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPA 302
Query: 338 KPAPSVSPGPWKPIPSVSPGPWKPTP-SVSSASWKSSSVSPSSWKSPPASPESWKSGPPE 396
P P P P S P +PTP ++ SA +P++ KS P +P+ + P
Sbjct: 303 LTTPK-EPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPK--EPAPTT 359
Query: 397 LRKTAPTLSPEHWKAVPPVSPELRKPGP------PLSPEIRSPAGSPELRKPSGSPDLWK 450
++ APT E P ++P P P +P+ +P +P+ P+ +
Sbjct: 360 TKEPAPTTPKE------PAPTTTKEPAPTTTKSAPTTPKEPAPT-TPKKPAPTTPKEPAP 412
Query: 451 LSPDQRKTSPASLDFPESQKSSRGGSPDLWKSSFFIEPQKPVFPETRKPGPSGPSESPKA 510
+P + P E +++ +P K P+KP ++P P+ P E
Sbjct: 413 TTPKE----PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPT 468
Query: 511 ASDIWKPVLSIDTEPRKPALFPEPAKTAPPASPEARKRALFPEPRKHALFPELPK 565
+ P T P++PA P K+AP + E P P P PK
Sbjct: 469 TTKEPSP-----TTPKEPA--PTTTKSAPTTTKE-------PAPTTTKSAPTTPK 509
Score = 52.0 bits (123), Expect = 2e-06
Identities = 77/383 (20%), Positives = 139/383 (36%), Gaps = 56/383 (14%)
Query: 95 PKNQLNKETDPVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESP-------- 146
PK KE P + E C+ P + + T K + +P+ P
Sbjct: 684 PKKPAPKELAPTTTK---EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGT 740
Query: 147 KPTPLTPLEPQKPGSVVSPELQTPLPSPEPSK-PASVSSPEPPKSVPVCESQKLAPVPSP 205
PT L P P EL +P +K P S +S +P + P + P+P
Sbjct: 741 APTTLKEPAPTTPKKPAPKEL-----APTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP 795
Query: 206 -EPQKPAPVSPESVKATLSNPKPQKQSHFPETL-GPPSASSPESPVLAASPEPWGPSPAA 263
P+KPAP +PE+ T S + P T+ P S+PE L+A P P
Sbjct: 796 TTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE---LSAEPTP------- 845
Query: 264 SPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPW 323
K+ + EP P+ +++P KP + + + + R
Sbjct: 846 -----KALENSPKEPGVPT-TKTPAATKPEMTTTAKDKT----------------TERDL 883
Query: 324 KSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSP 383
++ P ++ K K + + + + + T + + +K +++ ++
Sbjct: 884 RTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPK 943
Query: 384 PASPESWKSGPPELRKTAPTLSPE----HWKAVPPVSPELRKPGPPLSPEIRSPAGSPEL 439
+ + + + K T P+ + KA P P+ P + P P +
Sbjct: 944 VTTTKKTITTTEIMNKPEETAKPKDRATNSKATTP-KPQKPTKAPKKPTSTKKPKTMPRV 1002
Query: 440 RKPSGSPDLWKLSPDQRKTSPAS 462
RKP +P K++ + +P S
Sbjct: 1003 RKPKTTPTPRKMTSTMPELNPTS 1025
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 95.5 bits (236), Expect = 2e-19
Identities = 125/524 (23%), Positives = 196/524 (37%), Gaps = 76/524 (14%)
Query: 90 KWNDKPKNQLNKETDPVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKPT 149
K D KN+ K+ P PP+ + ++ + K + TQ SP+
Sbjct: 199 KVKDNKKNRTKKK--PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAK 256
Query: 150 PLTPLEPQKPGSVVSPEL------QTPLPSPEPSKP---------ASVSSPEPPKSVPVC 194
P+ P P S S E +T + + E + +S + +S+
Sbjct: 257 PINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKT 316
Query: 195 ESQKLAPV------PSPE------------PQKPAPVSP-ESVKATLSNPKPQKQSHFPE 235
++ LAP P+P+ P++P P +P E T P P P
Sbjct: 317 SAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPT 376
Query: 236 TLGPPSASSPESPVLAASPEPWGPSPAASPE-----SRKSARTTSPEP------RKPSPS 284
T P+ ++ +S A P P+P + E ++ A TT+ EP P+
Sbjct: 377 TPKEPAPTTTKS----APTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTP 432
Query: 285 ESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVS 344
+ P P P P+ PAP +P P P P P P+ P P +PAP+
Sbjct: 433 KEPAPTTPKKPAPTTPKEPAP-TTPKEPTPTTPKEPAPTTKEPA----PTTPKEPAPT-- 485
Query: 345 PGPWKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPPASPESWKSGPPELRKTAPTL 404
P KP P+ P PT A + SP++ K P +P + KS P ++ APT
Sbjct: 486 -APKKPAPTTPKEP-APTTPKEPAPTTTKEPSPTTPKEP--APTTTKSAPTTTKEPAPTT 541
Query: 405 SPEHWKAVPPVSPELRKPGPPLSPEIRSPAGSPELRKPSGSPDLWKLSPDQRKTSPASLD 464
+ SP K P +P+ +P +P+ P+ + +P + +
Sbjct: 542 TKSAPTTPKEPSPTTTKEPAPTTPKEPAPT-TPKKPAPTTPKEPAPTTPKEPAPTTTKKP 600
Query: 465 FPESQKSSRGGSPDLWKSSFFIEPQK--PVFPETRKPGPSGPSESPKAASDIWKPVLSID 522
P + K +P K + P+K P PE K P+ P + + P +
Sbjct: 601 APTTPKEPAPTTP---KETAPTTPKKLTPTTPE--KLAPTTPEKPAPTTPEELAPTTPEE 655
Query: 523 TEPRKPALFPEPAKTAP-PASPEARKRALFPEPRKHALFPELPK 565
P P EPA T P A+P K P++ A P PK
Sbjct: 656 PTPTTP---EEPAPTTPKAAAPNTPKEPAPTTPKEPA--PTTPK 694
Score = 93.2 bits (230), Expect = 9e-19
Identities = 114/491 (23%), Positives = 179/491 (36%), Gaps = 50/491 (10%)
Query: 94 KPKNQLNKETDPVK-SPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPK----- 147
KP KE P P P K P + + P ET +P +PK
Sbjct: 575 KPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET-------APTTPKKLTPT 627
Query: 148 -PTPLTPLEPQKPGSVVSPELQTPLP-SPEPSKPASVSSPEPPKSVPVCESQKLAPV--- 202
P L P P+KP EL P P P+ P +P PK+ ++ AP
Sbjct: 628 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE-PAPTTPKAAAPNTPKEPAPTTPK 686
Query: 203 -PSP-EPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPS 260
P+P P++PAP +P+ T PK P TL P+ ++P+ P +P+ P+
Sbjct: 687 EPAPTTPKEPAPTTPKETAPT--TPK----GTAPTTLKEPAPTTPKKP----APKELAPT 736
Query: 261 PAASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPAP-AVSPGSWK---PGP 316
P S P P P + P +P P EP P +P + K P
Sbjct: 737 TTKEP---TSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTT 793
Query: 317 PGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVS 376
P P P + P+ + GP S P P P + P +P P+ ++ +
Sbjct: 794 PKKPAPKELAPTTTKGP----TSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPET 849
Query: 377 PSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPELRKPGPPLSPEIRSPAGS 436
P S ++P + K P + K+ +PE A P P P P ++PA +
Sbjct: 850 PPPTTSEVSTPTTTKE-PTTIHKSPDESTPE-LSAEPTPKALENSPKEPGVPTTKTPAAT 907
Query: 437 -PELRKPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGSPDLWKSSFFIEPQKPVFPE 495
PE+ + + D R T + P+ K + + +S +
Sbjct: 908 KPEMTTTAKDKTTER---DLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTT 964
Query: 496 TRKPGPSGPSESPKAASDIWKPVLSIDTEPRKPALFPEPAKTAPPASPEARKRALFPEPR 555
T+ P + + + V + + +P +TA P +A P+P+
Sbjct: 965 TQDTTPF--KITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQ 1022
Query: 556 KHALFPELPKS 566
K P+ P S
Sbjct: 1023 KPTKAPKKPTS 1033
Score = 62.4 bits (150), Expect = 2e-09
Identities = 103/475 (21%), Positives = 168/475 (35%), Gaps = 80/475 (16%)
Query: 140 VLSPESPKPTPLTPLEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKL 199
V +P SP + P ++ S ++P P + + S E + V E+Q+
Sbjct: 107 VHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQES 166
Query: 200 APVPSP--------------------EPQKPAPVSPESVKATLSNPKPQ----------- 228
+ S E QK V T P P+
Sbjct: 167 SSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGL 226
Query: 229 KQSHFPETLGPPSASSPESPVLAASP-----EPWGPSPAASPESRKSARTTSPEPRKPSP 283
F T P S+ + ++ SP +P P P+ P S +++ TS K +
Sbjct: 227 DNGDFKVT--TPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNS-DTSKETSLTVNKETT 283
Query: 284 SESPEPWKPFPAVSPEPR------RPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPA 337
E+ E S + + + ++ S K P S K P A + PA
Sbjct: 284 VETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPA 343
Query: 338 KPAPSVSPGPWKPIPSVSPGPWKPTP-SVSSASWKSSSVSPSSWKSPPASPESWKSGPPE 396
P P P P S P +PTP ++ SA +P++ KS P +P+ + P
Sbjct: 344 LTTPK-EPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPK--EPAPTT 400
Query: 397 LRKTAPTLSPEHWKAVPPVSPELRKPGP------PLSPEIRSPAGSPELRKPSGSPDLWK 450
++ APT E P ++P P P +P+ +P +P+ P+ +
Sbjct: 401 TKEPAPTTPKE------PAPTTTKEPAPTTTKSAPTTPKEPAPT-TPKKPAPTTPKEPAP 453
Query: 451 LSPDQRKTSPASLDFPESQKSSRGGSPDLWKSSFFIEPQKPVFPETRKPGPSGPSESPKA 510
+P + P E +++ +P K P+KP ++P P+ P E
Sbjct: 454 TTPKE----PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPT 509
Query: 511 ASDIWKPVLSIDTEPRKPALFPEPAKTAPPASPEARKRALFPEPRKHALFPELPK 565
+ P T P++PA P K+AP + E P P P PK
Sbjct: 510 TTKEPSP-----TTPKEPA--PTTTKSAPTTTKE-------PAPTTTKSAPTTPK 550
Score = 52.0 bits (123), Expect = 2e-06
Identities = 77/383 (20%), Positives = 139/383 (36%), Gaps = 56/383 (14%)
Query: 95 PKNQLNKETDPVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESP-------- 146
PK KE P + E C+ P + + T K + +P+ P
Sbjct: 725 PKKPAPKELAPTTTK---EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGT 781
Query: 147 KPTPLTPLEPQKPGSVVSPELQTPLPSPEPSK-PASVSSPEPPKSVPVCESQKLAPVPSP 205
PT L P P EL +P +K P S +S +P + P + P+P
Sbjct: 782 APTTLKEPAPTTPKKPAPKEL-----APTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP 836
Query: 206 -EPQKPAPVSPESVKATLSNPKPQKQSHFPETL-GPPSASSPESPVLAASPEPWGPSPAA 263
P+KPAP +PE+ T S + P T+ P S+PE L+A P P
Sbjct: 837 TTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE---LSAEPTP------- 886
Query: 264 SPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPW 323
K+ + EP P+ +++P KP + + + + R
Sbjct: 887 -----KALENSPKEPGVPT-TKTPAATKPEMTTTAKDKT----------------TERDL 924
Query: 324 KSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSP 383
++ P ++ K K + + + + + T + + +K +++ ++
Sbjct: 925 RTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPK 984
Query: 384 PASPESWKSGPPELRKTAPTLSPE----HWKAVPPVSPELRKPGPPLSPEIRSPAGSPEL 439
+ + + + K T P+ + KA P P+ P + P P +
Sbjct: 985 VTTTKKTITTTEIMNKPEETAKPKDRATNSKATTP-KPQKPTKAPKKPTSTKKPKTMPRV 1043
Query: 440 RKPSGSPDLWKLSPDQRKTSPAS 462
RKP +P K++ + +P S
Sbjct: 1044 RKPKTTPTPRKMTSTMPELNPTS 1066
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 94.7 bits (234), Expect = 3e-19
Identities = 124/521 (23%), Positives = 195/521 (37%), Gaps = 76/521 (14%)
Query: 93 DKPKNQLNKETDPVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKPTPLT 152
D KN+ K+ P PP+ + ++ + K + TQ SP+ P+
Sbjct: 68 DNKKNRTKKK--PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPIN 125
Query: 153 PLEPQKPGSVVSPEL------QTPLPSPEPSKP---------ASVSSPEPPKSVPVCESQ 197
P P S S E +T + + E + +S + +S+ ++
Sbjct: 126 PRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK 185
Query: 198 KLAPV------PSPE------------PQKPAPVSP-ESVKATLSNPKPQKQSHFPETLG 238
LAP P+P+ P++P P +P E T P P P T
Sbjct: 186 DLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK 245
Query: 239 PPSASSPESPVLAASPEPWGPSPAASPE-----SRKSARTTSPEP------RKPSPSESP 287
P+ ++ +S A P P+P + E ++ A TT+ EP P+ + P
Sbjct: 246 EPAPTTTKS----APTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP 301
Query: 288 EPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGP 347
P P P+ PAP +P P P P P P+ P P +PAP+ P
Sbjct: 302 APTTPKKPAPTTPKEPAP-TTPKEPTPTTPKEPAPTTKEPA----PTTPKEPAPT---AP 353
Query: 348 WKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPPASPESWKSGPPELRKTAPTLSPE 407
KP P+ P PT A + SP++ K P +P + KS P ++ APT +
Sbjct: 354 KKPAPTTPKEP-APTTPKEPAPTTTKEPSPTTPKEP--APTTTKSAPTTTKEPAPTTTKS 410
Query: 408 HWKAVPPVSPELRKPGPPLSPEIRSPAGSPELRKPSGSPDLWKLSPDQRKTSPASLDFPE 467
SP K P +P+ +P +P+ P+ + +P + + P
Sbjct: 411 APTTPKEPSPTTTKEPAPTTPKEPAPT-TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT 469
Query: 468 SQKSSRGGSPDLWKSSFFIEPQK--PVFPETRKPGPSGPSESPKAASDIWKPVLSIDTEP 525
+ K +P K + P+K P PE K P+ P + + P + P
Sbjct: 470 TPKEPAPTTP---KETAPTTPKKLTPTTPE--KLAPTTPEKPAPTTPEELAPTTPEEPTP 524
Query: 526 RKPALFPEPAKTAP-PASPEARKRALFPEPRKHALFPELPK 565
P EPA T P A+P K P++ A P PK
Sbjct: 525 TTP---EEPAPTTPKAAAPNTPKEPAPTTPKEPA--PTTPK 560
Score = 93.2 bits (230), Expect = 9e-19
Identities = 114/491 (23%), Positives = 179/491 (36%), Gaps = 50/491 (10%)
Query: 94 KPKNQLNKETDPVK-SPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPK----- 147
KP KE P P P K P + + P ET +P +PK
Sbjct: 441 KPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET-------APTTPKKLTPT 493
Query: 148 -PTPLTPLEPQKPGSVVSPELQTPLP-SPEPSKPASVSSPEPPKSVPVCESQKLAPV--- 202
P L P P+KP EL P P P+ P +P PK+ ++ AP
Sbjct: 494 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE-PAPTTPKAAAPNTPKEPAPTTPK 552
Query: 203 -PSP-EPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPS 260
P+P P++PAP +P+ T PK P TL P+ ++P+ P +P+ P+
Sbjct: 553 EPAPTTPKEPAPTTPKETAPT--TPK----GTAPTTLKEPAPTTPKKP----APKELAPT 602
Query: 261 PAASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPAP-AVSPGSWK---PGP 316
P S P P P + P +P P EP P +P + K P
Sbjct: 603 TTKEP---TSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTT 659
Query: 317 PGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVS 376
P P P + P+ + GP S P P P + P +P P+ ++ +
Sbjct: 660 PKKPAPKELAPTTTKGP----TSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPET 715
Query: 377 PSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPELRKPGPPLSPEIRSPAGS 436
P S ++P + K P + K+ +PE A P P P P ++PA +
Sbjct: 716 PPPTTSEVSTPTTTKE-PTTIHKSPDESTPE-LSAEPTPKALENSPKEPGVPTTKTPAAT 773
Query: 437 -PELRKPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGSPDLWKSSFFIEPQKPVFPE 495
PE+ + + D R T + P+ K + + +S +
Sbjct: 774 KPEMTTTAKDKTTER---DLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTT 830
Query: 496 TRKPGPSGPSESPKAASDIWKPVLSIDTEPRKPALFPEPAKTAPPASPEARKRALFPEPR 555
T+ P + + + V + + +P +TA P +A P+P+
Sbjct: 831 TQDTTPF--KITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQ 888
Query: 556 KHALFPELPKS 566
K P+ P S
Sbjct: 889 KPTKAPKKPTS 899
Score = 52.0 bits (123), Expect = 2e-06
Identities = 77/383 (20%), Positives = 139/383 (36%), Gaps = 56/383 (14%)
Query: 95 PKNQLNKETDPVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESP-------- 146
PK KE P + E C+ P + + T K + +P+ P
Sbjct: 591 PKKPAPKELAPTTTK---EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGT 647
Query: 147 KPTPLTPLEPQKPGSVVSPELQTPLPSPEPSK-PASVSSPEPPKSVPVCESQKLAPVPSP 205
PT L P P EL +P +K P S +S +P + P + P+P
Sbjct: 648 APTTLKEPAPTTPKKPAPKEL-----APTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP 702
Query: 206 -EPQKPAPVSPESVKATLSNPKPQKQSHFPETL-GPPSASSPESPVLAASPEPWGPSPAA 263
P+KPAP +PE+ T S + P T+ P S+PE L+A P P
Sbjct: 703 TTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE---LSAEPTP------- 752
Query: 264 SPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPW 323
K+ + EP P+ +++P KP + + + + R
Sbjct: 753 -----KALENSPKEPGVPT-TKTPAATKPEMTTTAKDKT----------------TERDL 790
Query: 324 KSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSP 383
++ P ++ K K + + + + + T + + +K +++ ++
Sbjct: 791 RTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPK 850
Query: 384 PASPESWKSGPPELRKTAPTLSPE----HWKAVPPVSPELRKPGPPLSPEIRSPAGSPEL 439
+ + + + K T P+ + KA P P+ P + P P +
Sbjct: 851 VTTTKKTITTTEIMNKPEETAKPKDRATNSKATTP-KPQKPTKAPKKPTSTKKPKTMPRV 909
Query: 440 RKPSGSPDLWKLSPDQRKTSPAS 462
RKP +P K++ + +P S
Sbjct: 910 RKPKTTPTPRKMTSTMPELNPTS 932
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 94.7 bits (234), Expect = 3e-19
Identities = 124/521 (23%), Positives = 195/521 (37%), Gaps = 76/521 (14%)
Query: 93 DKPKNQLNKETDPVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKPTPLT 152
D KN+ K+ P PP+ + ++ + K + TQ SP+ P+
Sbjct: 109 DNKKNRTKKK--PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPIN 166
Query: 153 PLEPQKPGSVVSPEL------QTPLPSPEPSKP---------ASVSSPEPPKSVPVCESQ 197
P P S S E +T + + E + +S + +S+ ++
Sbjct: 167 PRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK 226
Query: 198 KLAPV------PSPE------------PQKPAPVSP-ESVKATLSNPKPQKQSHFPETLG 238
LAP P+P+ P++P P +P E T P P P T
Sbjct: 227 DLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK 286
Query: 239 PPSASSPESPVLAASPEPWGPSPAASPE-----SRKSARTTSPEP------RKPSPSESP 287
P+ ++ +S A P P+P + E ++ A TT+ EP P+ + P
Sbjct: 287 EPAPTTTKS----APTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP 342
Query: 288 EPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGP 347
P P P+ PAP +P P P P P P+ P P +PAP+ P
Sbjct: 343 APTTPKKPAPTTPKEPAP-TTPKEPTPTTPKEPAPTTKEPA----PTTPKEPAPT---AP 394
Query: 348 WKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPPASPESWKSGPPELRKTAPTLSPE 407
KP P+ P PT A + SP++ K P +P + KS P ++ APT +
Sbjct: 395 KKPAPTTPKEP-APTTPKEPAPTTTKEPSPTTPKEP--APTTTKSAPTTTKEPAPTTTKS 451
Query: 408 HWKAVPPVSPELRKPGPPLSPEIRSPAGSPELRKPSGSPDLWKLSPDQRKTSPASLDFPE 467
SP K P +P+ +P +P+ P+ + +P + + P
Sbjct: 452 APTTPKEPSPTTTKEPAPTTPKEPAPT-TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT 510
Query: 468 SQKSSRGGSPDLWKSSFFIEPQK--PVFPETRKPGPSGPSESPKAASDIWKPVLSIDTEP 525
+ K +P K + P+K P PE K P+ P + + P + P
Sbjct: 511 TPKEPAPTTP---KETAPTTPKKLTPTTPE--KLAPTTPEKPAPTTPEELAPTTPEEPTP 565
Query: 526 RKPALFPEPAKTAP-PASPEARKRALFPEPRKHALFPELPK 565
P EPA T P A+P K P++ A P PK
Sbjct: 566 TTP---EEPAPTTPKAAAPNTPKEPAPTTPKEPA--PTTPK 601
Score = 93.2 bits (230), Expect = 9e-19
Identities = 114/491 (23%), Positives = 179/491 (36%), Gaps = 50/491 (10%)
Query: 94 KPKNQLNKETDPVK-SPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPK----- 147
KP KE P P P K P + + P ET +P +PK
Sbjct: 482 KPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET-------APTTPKKLTPT 534
Query: 148 -PTPLTPLEPQKPGSVVSPELQTPLP-SPEPSKPASVSSPEPPKSVPVCESQKLAPV--- 202
P L P P+KP EL P P P+ P +P PK+ ++ AP
Sbjct: 535 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE-PAPTTPKAAAPNTPKEPAPTTPK 593
Query: 203 -PSP-EPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPS 260
P+P P++PAP +P+ T PK P TL P+ ++P+ P +P+ P+
Sbjct: 594 EPAPTTPKEPAPTTPKETAPT--TPK----GTAPTTLKEPAPTTPKKP----APKELAPT 643
Query: 261 PAASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPAP-AVSPGSWK---PGP 316
P S P P P + P +P P EP P +P + K P
Sbjct: 644 TTKEP---TSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTT 700
Query: 317 PGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVS 376
P P P + P+ + GP S P P P + P +P P+ ++ +
Sbjct: 701 PKKPAPKELAPTTTKGP----TSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPET 756
Query: 377 PSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPELRKPGPPLSPEIRSPAGS 436
P S ++P + K P + K+ +PE A P P P P ++PA +
Sbjct: 757 PPPTTSEVSTPTTTKE-PTTIHKSPDESTPE-LSAEPTPKALENSPKEPGVPTTKTPAAT 814
Query: 437 -PELRKPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGSPDLWKSSFFIEPQKPVFPE 495
PE+ + + D R T + P+ K + + +S +
Sbjct: 815 KPEMTTTAKDKTTER---DLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTT 871
Query: 496 TRKPGPSGPSESPKAASDIWKPVLSIDTEPRKPALFPEPAKTAPPASPEARKRALFPEPR 555
T+ P + + + V + + +P +TA P +A P+P+
Sbjct: 872 TQDTTPF--KITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQ 929
Query: 556 KHALFPELPKS 566
K P+ P S
Sbjct: 930 KPTKAPKKPTS 940
Score = 52.0 bits (123), Expect = 2e-06
Identities = 77/383 (20%), Positives = 139/383 (36%), Gaps = 56/383 (14%)
Query: 95 PKNQLNKETDPVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESP-------- 146
PK KE P + E C+ P + + T K + +P+ P
Sbjct: 632 PKKPAPKELAPTTTK---EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGT 688
Query: 147 KPTPLTPLEPQKPGSVVSPELQTPLPSPEPSK-PASVSSPEPPKSVPVCESQKLAPVPSP 205
PT L P P EL +P +K P S +S +P + P + P+P
Sbjct: 689 APTTLKEPAPTTPKKPAPKEL-----APTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP 743
Query: 206 -EPQKPAPVSPESVKATLSNPKPQKQSHFPETL-GPPSASSPESPVLAASPEPWGPSPAA 263
P+KPAP +PE+ T S + P T+ P S+PE L+A P P
Sbjct: 744 TTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE---LSAEPTP------- 793
Query: 264 SPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPW 323
K+ + EP P+ +++P KP + + + + R
Sbjct: 794 -----KALENSPKEPGVPT-TKTPAATKPEMTTTAKDKT----------------TERDL 831
Query: 324 KSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSP 383
++ P ++ K K + + + + + T + + +K +++ ++
Sbjct: 832 RTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPK 891
Query: 384 PASPESWKSGPPELRKTAPTLSPE----HWKAVPPVSPELRKPGPPLSPEIRSPAGSPEL 439
+ + + + K T P+ + KA P P+ P + P P +
Sbjct: 892 VTTTKKTITTTEIMNKPEETAKPKDRATNSKATTP-KPQKPTKAPKKPTSTKKPKTMPRV 950
Query: 440 RKPSGSPDLWKLSPDQRKTSPAS 462
RKP +P K++ + +P S
Sbjct: 951 RKPKTTPTPRKMTSTMPELNPTS 973
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 93.6 bits (231), Expect = 7e-19
Identities = 102/416 (24%), Positives = 155/416 (37%), Gaps = 58/416 (13%)
Query: 145 SPKPTPLTPLEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCE-SQKLAPVP 203
SP PT T L P S + TP P+ PS P + ++ PP + P S P P
Sbjct: 1407 SPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPP 1466
Query: 204 SPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPAA 263
+ P P +P T S P + P T P ++P +P + + P P
Sbjct: 1467 TTTPSPPT-TTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLP----PTT 1521
Query: 264 SPESRKSARTTSPEPRKPSPSESPEPWKPF------PAVSPEPRRPAPAVSPGSWKPGPP 317
+P + TT P PSP + P P +P P P + P PP
Sbjct: 1522 TPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPP 1581
Query: 318 GSPRPWKSNPSASSGPWKPAKPAPSVSPGP-----WKPIPSVSPGPWKPTPSVSSASWKS 372
+ P S P+ ++ P P+ +P P P P+ +P P TP S +
Sbjct: 1582 TTTTP--SPPTITT-----TTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTS--T 1632
Query: 373 SSVSPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPELRKP--GPPLSPEI 430
+++ P++ SPP P + + PP + PT + PP++ P P SP
Sbjct: 1633 TTLPPTTTPSPP--PTTTTTPPPTTTPSPPTTTTPS----PPITTTTTPPPTTTPSSPIT 1686
Query: 431 RSPAGSPELRKPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGSPDLWKSSFFIEPQK 490
+P+ P + SP SP T+P+S P ++ + S P
Sbjct: 1687 TTPS-PPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTT------MTTPSPTTTPSP 1739
Query: 491 PVFPETRKPGPSGPSESPKAASDIWKPVLSIDTEPRKPALFP---EPAKTAPPASP 543
P T P + + SP + T P P++ P P T P +P
Sbjct: 1740 PTTTMTTLPPTT--TSSP------------LTTTPLPPSITPPTFSPFSTTTPTTP 1781
Score = 87.8 bits (216), Expect = 4e-17
Identities = 87/366 (23%), Positives = 134/366 (36%), Gaps = 49/366 (13%)
Query: 121 SAEPKSIPALSMETQKLGSVLSPESPKPT-----PLTPLEPQKPGSVVSPELQT---PLP 172
S P S L T + +P PT P+T P + SP + T P P
Sbjct: 1407 SPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPP 1466
Query: 173 SPEPSKPASVSSPEPPK-SVPVCESQKLAPVPSPEPQKPAPVSPESVKATL--------- 222
+ PS P + SP S P + P +P P P++P + TL
Sbjct: 1467 TTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPP 1526
Query: 223 ----SNPKPQKQSHFPET--LGPPSASSPESPVLAASPEPWGPSPAASPESRKSARTTSP 276
+ P P P T + PP++++ P SP P + + TT+P
Sbjct: 1527 TTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTP 1586
Query: 277 EP-----RKPSPSESPEP-----WKPFPAVSPEPRRPAPAVSPGSWKPGPP---GSPRPW 323
P P P+ +P P P P +P P P P S PP SP P
Sbjct: 1587 SPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPT 1646
Query: 324 KSN---PSASSGPWKPAKPAPSVS-----PGPWKPIPSVSPGPWKPTPSVSSASWKSSSV 375
+ P+ + P P+P ++ P P ++ P PT ++++ S ++
Sbjct: 1647 TTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPS 1706
Query: 376 SPSSWKSPPASPESWKSGPPELRKTAPTLSPE----HWKAVPPVSPELRKPGPPLSPEIR 431
SP + + P+S + P + +PT +P +PP + PL P I
Sbjct: 1707 SPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSIT 1766
Query: 432 SPAGSP 437
P SP
Sbjct: 1767 PPTFSP 1772
Score = 73.6 bits (179), Expect = 7e-13
Identities = 60/289 (20%), Positives = 100/289 (34%), Gaps = 24/289 (8%)
Query: 88 PDKWNDKPKNQLNKETDPVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPK 147
P P P +P P I ++ P + + P +
Sbjct: 1518 PPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTT 1577
Query: 148 PTPLTPLEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSPEP 207
P+P T P P + TP P+ PS P + ++ PP + P + P+
Sbjct: 1578 PSPPTTTTPSPPTITTT----TPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTT 1633
Query: 208 QKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPAASPES 267
P +P T + P P T PP+ ++P P+ + P P +P S
Sbjct: 1634 TLPPTTTPSPPPTTTTTPPP------TTTPSPPTTTTPSPPITTTTT----PPPTTTPSS 1683
Query: 268 RKSARTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSW-KPGPPGSPRPWKSN 326
+ + P +PS + P P + P+ P + P P +P P +
Sbjct: 1684 PITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTT 1743
Query: 327 -----PSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASW 370
P+ +S P PS++P + P + +P TP V +W
Sbjct: 1744 MTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTP----TTPCVPLCNW 1788
Score = 64.7 bits (156), Expect = 3e-10
Identities = 70/289 (24%), Positives = 99/289 (34%), Gaps = 28/289 (9%)
Query: 261 PAASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSP 320
P +P ++ TT P PSP + P P +P P P + P PP S
Sbjct: 1402 PTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPP-PTTTPSPPITTTTTPPPTTTPSPPIST 1460
Query: 321 RPWKSNPSASSGPWKPAKPAPSVSPGP-----WKPIPSVSPGPWKPTPSVSSASWKSSSV 375
+ S P P P+ +P P P P+ +P P TP AS ++++
Sbjct: 1461 TTTPPPTTTPSPPTTTPSP-PTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPAS--TTTL 1517
Query: 376 SPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPELRKPGPPLSPEIRSPAG 435
P++ SPP + + + PP + PT +P PP S P SP +
Sbjct: 1518 PPTTTPSPPTTTTT--TPPPTTTPSPPTTTP----ITPPTSTTTLPPTTTPSPPPTTTTT 1571
Query: 436 SPELRKPSGSPDLWKLSPDQRKTSPASLDFPE-SQKSSRGGSPDLWKSSFFIEPQKPVFP 494
P PS P T+P P ++ P S P P
Sbjct: 1572 PPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTS 1631
Query: 495 ETRKPGPSGPSESPKAASDIWKPVLSIDTEPRKPALFPEPAKTAPPASP 543
T P + PS P + T P P P P T P+ P
Sbjct: 1632 TTTLPPTTTPSPPPTTTT----------TPP--PTTTPSPPTTTTPSPP 1668
Score = 60.5 bits (145), Expect = 6e-09
Identities = 97/464 (20%), Positives = 166/464 (35%), Gaps = 47/464 (10%)
Query: 95 PKNQLNKETDPVKSPPLPEHQKIPCNSAEPKSIPALSMET-QKLGSVLSPESPKPTPLTP 153
P T P+ + P + P + P + T + ++P TP+T
Sbjct: 3891 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3950
Query: 154 LEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEP-----PKSVPVCESQKLAPVPSPEPQ 208
P + QTP +P + +P P P + P+ + + P P+P
Sbjct: 3951 TTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4009
Query: 209 KPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWG-PSPAASPES 267
+ +P + T++ P P T P + ++ +P +P P G +P +P +
Sbjct: 4010 QTPTTTPITTTTTVT-PTPTPTGTQTPTTTPITTTTTVTP----TPTPTGTQTPTTTPIT 4064
Query: 268 RKSARTTSPEPR-KPSPSESPEPWKPFPAVSPEP-------RRPAPAVSPGSWKPGPPGS 319
+ T +P P +P+ +P +P P P + + P P G+
Sbjct: 4065 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4124
Query: 320 PRPWKSNPSASSGPWKPAKPAPSVSPGP-WKPIPSVSPGPWKPTPSVSSASWKSSSVSPS 378
P + P ++ P P P+ + P PI + + PTP+ + + ++ ++ +
Sbjct: 4125 QTP-TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTT 4181
Query: 379 SWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPELRKPGPPLSPEIRSPAGSPE 438
+ +P +P ++GPP TAP EL PP PE +P S
Sbjct: 4182 TTVTPTPTPTGTQTGPPTHTSTAPI-------------AELTTSNPP--PESSTPQTSRS 4226
Query: 439 LRKP--SGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGSPDLWKSSFFIEPQKPVFPET 496
P + L L P TS A P + ++ GG S P T
Sbjct: 4227 TSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGT 4286
Query: 497 RKPGPSGPSES--PKAASDIWKPV---LSIDTEPRKPALFPEPA 535
S P+ S + W P LS + R L P P+
Sbjct: 4287 TTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPS 4330
Score = 52.4 bits (124), Expect = 2e-06
Identities = 83/367 (22%), Positives = 129/367 (35%), Gaps = 51/367 (13%)
Query: 95 PKNQLNKETDPVKSPPLPEHQKIPCNSAEPKSIPALSMET-QKLGSVLSPESPKPTPLTP 153
P T P+ + P + P + P + T + ++P TP+T
Sbjct: 4075 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 4134
Query: 154 LEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEP-----PKSVPVCESQKLAPVPSPEPQ 208
P + QTP +P + +P P P + P+ + + P P+P
Sbjct: 4135 TTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4193
Query: 209 KPAPVSPESV----KATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPAAS 264
+ P + S + T SNP P+ S P+T S+ ES L ++ P + +
Sbjct: 4194 QTGPPTHTSTAPIAELTTSNPPPE--SSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTA 4251
Query: 265 PESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPR--- 321
P S +A TT+ SP P SP P P + GS P + +
Sbjct: 4252 PPSTPTAPTTTSGGHTLSP-------PPSTTTSP-PGTPTRGTTTGSSSAPTPSTVQTTT 4303
Query: 322 --PWKSNPSASSGP----WKPAKPAPS-------VSPGPWKPIPSVSPGPWKPTPSVSSA 368
W P+ S P +P PS ++ + P V G + T +
Sbjct: 4304 TSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNC 4363
Query: 369 SWKSSSVSPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPELRKPG--PPL 426
S S ++ +W P S S P K+ PT S P +P PG PP
Sbjct: 4364 S-LSCTLEFYNWSCP-----STPSPTPTPSKSTPTPSK------PSSTPSKPTPGTKPPE 4411
Query: 427 SPEIRSP 433
P+ P
Sbjct: 4412 CPDFDPP 4418
Score = 45.8 bits (107), Expect = 2e-04
Identities = 60/314 (19%), Positives = 121/314 (38%), Gaps = 25/314 (7%)
Query: 103 TDPVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKPTPLTPLEPQKPGSV 162
T ++P P I + + +T + + + PTP TP Q P +
Sbjct: 1887 TTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTT 1945
Query: 163 VSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQKPAPVSPESVKATL 222
T P+P P+ + P + P+ + + P P+P + +P + T+
Sbjct: 1946 PITTTTTVTPTPTPT------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 1999
Query: 223 SNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWG-PSPAASPESRKSARTTSPEPR-K 280
+ P P T P + ++ +P +P P G +P +P + + T +P P
Sbjct: 2000 T-PTPTPTGTQTPTTTPITTTTTVTP----TPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2054
Query: 281 PSPSESPEPWKPFPAVSPEP-------RRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGP 333
+P+ +P +P P P + + P P G+ P + P ++
Sbjct: 2055 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTT 2113
Query: 334 WKPAKPAPSVSPGP-WKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPPASPESWKS 392
P P P+ + P PI + + PTP+ + + ++ ++ ++ +P +P ++
Sbjct: 2114 VTPT-PTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 2171
Query: 393 GPPELRKTAPTLSP 406
T T++P
Sbjct: 2172 PTTTPITTTTTVTP 2185
Score = 45.4 bits (106), Expect = 2e-04
Identities = 62/328 (18%), Positives = 124/328 (37%), Gaps = 25/328 (7%)
Query: 95 PKNQLNKETDPVKSPPLPEHQKIPCNSAEPKSIPALSMET-QKLGSVLSPESPKPTPLTP 153
P T P+ + P + P + P + T + ++P TP+T
Sbjct: 2051 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2110
Query: 154 LEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEP-----PKSVPVCESQKLAPVPSPEPQ 208
P + QTP +P + +P P P + P+ + + P P+P
Sbjct: 2111 TTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2169
Query: 209 KPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWG-PSPAASPES 267
+ +P + T++ P P T P + ++ +P +P P G +P +P +
Sbjct: 2170 QTPTTTPITTTTTVT-PTPTPTGTQTPTTTPITTTTTVTP----TPTPTGTQTPTTTPIT 2224
Query: 268 RKSARTTSPEPR-KPSPSESPEPWKPFPAVSPEP-------RRPAPAVSPGSWKPGPPGS 319
+ T +P P +P+ +P +P P P + + P P G+
Sbjct: 2225 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2284
Query: 320 PRPWKSNPSASSGPWKPAKPAPSVSPGP-WKPIPSVSPGPWKPTPSVSSASWKSSSVSPS 378
P + P ++ P P P+ + P PI + + PTP+ + + ++ ++ +
Sbjct: 2285 QTP-TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTT 2341
Query: 379 SWKSPPASPESWKSGPPELRKTAPTLSP 406
+ +P +P ++ T T++P
Sbjct: 2342 TTVTPTPTPTGTQTPTTTPITTTTTVTP 2369
Score = 45.4 bits (106), Expect = 2e-04
Identities = 62/328 (18%), Positives = 124/328 (37%), Gaps = 25/328 (7%)
Query: 95 PKNQLNKETDPVKSPPLPEHQKIPCNSAEPKSIPALSMET-QKLGSVLSPESPKPTPLTP 153
P T P+ + P + P + P + T + ++P TP+T
Sbjct: 2235 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2294
Query: 154 LEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEP-----PKSVPVCESQKLAPVPSPEPQ 208
P + QTP +P + +P P P + P+ + + P P+P
Sbjct: 2295 TTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2353
Query: 209 KPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWG-PSPAASPES 267
+ +P + T++ P P T P + ++ +P +P P G +P +P +
Sbjct: 2354 QTPTTTPITTTTTVT-PTPTPTGTQTPTTTPITTTTTVTP----TPTPTGTQTPTTTPIT 2408
Query: 268 RKSARTTSPEPR-KPSPSESPEPWKPFPAVSPEP-------RRPAPAVSPGSWKPGPPGS 319
+ T +P P +P+ +P +P P P + + P P G+
Sbjct: 2409 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2468
Query: 320 PRPWKSNPSASSGPWKPAKPAPSVSPGP-WKPIPSVSPGPWKPTPSVSSASWKSSSVSPS 378
P + P ++ P P P+ + P PI + + PTP+ + + ++ ++ +
Sbjct: 2469 QTP-TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTT 2525
Query: 379 SWKSPPASPESWKSGPPELRKTAPTLSP 406
+ +P +P ++ T T++P
Sbjct: 2526 TTVTPTPTPTGTQTPTTTPITTTTTVTP 2553
Score = 45.4 bits (106), Expect = 2e-04
Identities = 62/328 (18%), Positives = 124/328 (37%), Gaps = 25/328 (7%)
Query: 95 PKNQLNKETDPVKSPPLPEHQKIPCNSAEPKSIPALSMET-QKLGSVLSPESPKPTPLTP 153
P T P+ + P + P + P + T + ++P TP+T
Sbjct: 2419 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2478
Query: 154 LEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEP-----PKSVPVCESQKLAPVPSPEPQ 208
P + QTP +P + +P P P + P+ + + P P+P
Sbjct: 2479 TTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2537
Query: 209 KPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWG-PSPAASPES 267
+ +P + T++ P P T P + ++ +P +P P G +P +P +
Sbjct: 2538 QTPTTTPITTTTTVT-PTPTPTGTQTPTTTPITTTTTVTP----TPTPTGTQTPTTTPIT 2592
Query: 268 RKSARTTSPEPR-KPSPSESPEPWKPFPAVSPEP-------RRPAPAVSPGSWKPGPPGS 319
+ T +P P +P+ +P +P P P + + P P G+
Sbjct: 2593 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2652
Query: 320 PRPWKSNPSASSGPWKPAKPAPSVSPGP-WKPIPSVSPGPWKPTPSVSSASWKSSSVSPS 378
P + P ++ P P P+ + P PI + + PTP+ + + ++ ++ +
Sbjct: 2653 QTP-TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTT 2709
Query: 379 SWKSPPASPESWKSGPPELRKTAPTLSP 406
+ +P +P ++ T T++P
Sbjct: 2710 TTVTPTPTPTGTQTPTTTPITTTTTVTP 2737
Score = 45.4 bits (106), Expect = 2e-04
Identities = 62/328 (18%), Positives = 124/328 (37%), Gaps = 25/328 (7%)
Query: 95 PKNQLNKETDPVKSPPLPEHQKIPCNSAEPKSIPALSMET-QKLGSVLSPESPKPTPLTP 153
P T P+ + P + P + P + T + ++P TP+T
Sbjct: 2603 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2662
Query: 154 LEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEP-----PKSVPVCESQKLAPVPSPEPQ 208
P + QTP +P + +P P P + P+ + + P P+P
Sbjct: 2663 TTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2721
Query: 209 KPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWG-PSPAASPES 267
+ +P + T++ P P T P + ++ +P +P P G +P +P +
Sbjct: 2722 QTPTTTPITTTTTVT-PTPTPTGTQTPTTTPITTTTTVTP----TPTPTGTQTPTTTPIT 2776
Query: 268 RKSARTTSPEPR-KPSPSESPEPWKPFPAVSPEP-------RRPAPAVSPGSWKPGPPGS 319
+ T +P P +P+ +P +P P P + + P P G+
Sbjct: 2777 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2836
Query: 320 PRPWKSNPSASSGPWKPAKPAPSVSPGP-WKPIPSVSPGPWKPTPSVSSASWKSSSVSPS 378
P + P ++ P P P+ + P PI + + PTP+ + + ++ ++ +
Sbjct: 2837 QTP-TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTT 2893
Query: 379 SWKSPPASPESWKSGPPELRKTAPTLSP 406
+ +P +P ++ T T++P
Sbjct: 2894 TTVTPTPTPTGTQTPTTTPITTTTTVTP 2921
Score = 45.4 bits (106), Expect = 2e-04
Identities = 62/328 (18%), Positives = 124/328 (37%), Gaps = 25/328 (7%)
Query: 95 PKNQLNKETDPVKSPPLPEHQKIPCNSAEPKSIPALSMET-QKLGSVLSPESPKPTPLTP 153
P T P+ + P + P + P + T + ++P TP+T
Sbjct: 2787 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2846
Query: 154 LEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEP-----PKSVPVCESQKLAPVPSPEPQ 208
P + QTP +P + +P P P + P+ + + P P+P
Sbjct: 2847 TTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2905
Query: 209 KPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWG-PSPAASPES 267
+ +P + T++ P P T P + ++ +P +P P G +P +P +
Sbjct: 2906 QTPTTTPITTTTTVT-PTPTPTGTQTPTTTPITTTTTVTP----TPTPTGTQTPTTTPIT 2960
Query: 268 RKSARTTSPEPR-KPSPSESPEPWKPFPAVSPEP-------RRPAPAVSPGSWKPGPPGS 319
+ T +P P +P+ +P +P P P + + P P G+
Sbjct: 2961 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3020
Query: 320 PRPWKSNPSASSGPWKPAKPAPSVSPGP-WKPIPSVSPGPWKPTPSVSSASWKSSSVSPS 378
P + P ++ P P P+ + P PI + + PTP+ + + ++ ++ +
Sbjct: 3021 QTP-TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTT 3077
Query: 379 SWKSPPASPESWKSGPPELRKTAPTLSP 406
+ +P +P ++ T T++P
Sbjct: 3078 TTVTPTPTPTGTQTPTTTPITTTTTVTP 3105
Score = 45.4 bits (106), Expect = 2e-04
Identities = 62/328 (18%), Positives = 124/328 (37%), Gaps = 25/328 (7%)
Query: 95 PKNQLNKETDPVKSPPLPEHQKIPCNSAEPKSIPALSMET-QKLGSVLSPESPKPTPLTP 153
P T P+ + P + P + P + T + ++P TP+T
Sbjct: 2971 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3030
Query: 154 LEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEP-----PKSVPVCESQKLAPVPSPEPQ 208
P + QTP +P + +P P P + P+ + + P P+P
Sbjct: 3031 TTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3089
Query: 209 KPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWG-PSPAASPES 267
+ +P + T++ P P T P + ++ +P +P P G +P +P +
Sbjct: 3090 QTPTTTPITTTTTVT-PTPTPTGTQTPTTTPITTTTTVTP----TPTPTGTQTPTTTPIT 3144
Query: 268 RKSARTTSPEPR-KPSPSESPEPWKPFPAVSPEP-------RRPAPAVSPGSWKPGPPGS 319
+ T +P P +P+ +P +P P P + + P P G+
Sbjct: 3145 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3204
Query: 320 PRPWKSNPSASSGPWKPAKPAPSVSPGP-WKPIPSVSPGPWKPTPSVSSASWKSSSVSPS 378
P + P ++ P P P+ + P PI + + PTP+ + + ++ ++ +
Sbjct: 3205 QTP-TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTT 3261
Query: 379 SWKSPPASPESWKSGPPELRKTAPTLSP 406
+ +P +P ++ T T++P
Sbjct: 3262 TTVTPTPTPTGTQTPTTTPITTTTTVTP 3289
Score = 45.4 bits (106), Expect = 2e-04
Identities = 62/328 (18%), Positives = 124/328 (37%), Gaps = 25/328 (7%)
Query: 95 PKNQLNKETDPVKSPPLPEHQKIPCNSAEPKSIPALSMET-QKLGSVLSPESPKPTPLTP 153
P T P+ + P + P + P + T + ++P TP+T
Sbjct: 3155 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3214
Query: 154 LEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEP-----PKSVPVCESQKLAPVPSPEPQ 208
P + QTP +P + +P P P + P+ + + P P+P
Sbjct: 3215 TTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3273
Query: 209 KPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWG-PSPAASPES 267
+ +P + T++ P P T P + ++ +P +P P G +P +P +
Sbjct: 3274 QTPTTTPITTTTTVT-PTPTPTGTQTPTTTPITTTTTVTP----TPTPTGTQTPTTTPIT 3328
Query: 268 RKSARTTSPEPR-KPSPSESPEPWKPFPAVSPEP-------RRPAPAVSPGSWKPGPPGS 319
+ T +P P +P+ +P +P P P + + P P G+
Sbjct: 3329 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3388
Query: 320 PRPWKSNPSASSGPWKPAKPAPSVSPGP-WKPIPSVSPGPWKPTPSVSSASWKSSSVSPS 378
P + P ++ P P P+ + P PI + + PTP+ + + ++ ++ +
Sbjct: 3389 QTP-TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTT 3445
Query: 379 SWKSPPASPESWKSGPPELRKTAPTLSP 406
+ +P +P ++ T T++P
Sbjct: 3446 TTVTPTPTPTGTQTPTTTPITTTTTVTP 3473
Score = 45.4 bits (106), Expect = 2e-04
Identities = 62/328 (18%), Positives = 124/328 (37%), Gaps = 25/328 (7%)
Query: 95 PKNQLNKETDPVKSPPLPEHQKIPCNSAEPKSIPALSMET-QKLGSVLSPESPKPTPLTP 153
P T P+ + P + P + P + T + ++P TP+T
Sbjct: 3339 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3398
Query: 154 LEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEP-----PKSVPVCESQKLAPVPSPEPQ 208
P + QTP +P + +P P P + P+ + + P P+P
Sbjct: 3399 TTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3457
Query: 209 KPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWG-PSPAASPES 267
+ +P + T++ P P T P + ++ +P +P P G +P +P +
Sbjct: 3458 QTPTTTPITTTTTVT-PTPTPTGTQTPTTTPITTTTTVTP----TPTPTGTQTPTTTPIT 3512
Query: 268 RKSARTTSPEPR-KPSPSESPEPWKPFPAVSPEP-------RRPAPAVSPGSWKPGPPGS 319
+ T +P P +P+ +P +P P P + + P P G+
Sbjct: 3513 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3572
Query: 320 PRPWKSNPSASSGPWKPAKPAPSVSPGP-WKPIPSVSPGPWKPTPSVSSASWKSSSVSPS 378
P + P ++ P P P+ + P PI + + PTP+ + + ++ ++ +
Sbjct: 3573 QTP-TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTT 3629
Query: 379 SWKSPPASPESWKSGPPELRKTAPTLSP 406
+ +P +P ++ T T++P
Sbjct: 3630 TTVTPTPTPTGTQTPTTTPITTTTTVTP 3657
Score = 45.4 bits (106), Expect = 2e-04
Identities = 62/328 (18%), Positives = 124/328 (37%), Gaps = 25/328 (7%)
Query: 95 PKNQLNKETDPVKSPPLPEHQKIPCNSAEPKSIPALSMET-QKLGSVLSPESPKPTPLTP 153
P T P+ + P + P + P + T + ++P TP+T
Sbjct: 3523 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3582
Query: 154 LEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEP-----PKSVPVCESQKLAPVPSPEPQ 208
P + QTP +P + +P P P + P+ + + P P+P
Sbjct: 3583 TTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3641
Query: 209 KPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWG-PSPAASPES 267
+ +P + T++ P P T P + ++ +P +P P G +P +P +
Sbjct: 3642 QTPTTTPITTTTTVT-PTPTPTGTQTPTTTPITTTTTVTP----TPTPTGTQTPTTTPIT 3696
Query: 268 RKSARTTSPEPR-KPSPSESPEPWKPFPAVSPEP-------RRPAPAVSPGSWKPGPPGS 319
+ T +P P +P+ +P +P P P + + P P G+
Sbjct: 3697 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3756
Query: 320 PRPWKSNPSASSGPWKPAKPAPSVSPGP-WKPIPSVSPGPWKPTPSVSSASWKSSSVSPS 378
P + P ++ P P P+ + P PI + + PTP+ + + ++ ++ +
Sbjct: 3757 QTP-TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTT 3813
Query: 379 SWKSPPASPESWKSGPPELRKTAPTLSP 406
+ +P +P ++ T T++P
Sbjct: 3814 TTVTPTPTPTGTQTPTTTPITTTTTVTP 3841
Score = 45.4 bits (106), Expect = 2e-04
Identities = 62/328 (18%), Positives = 124/328 (37%), Gaps = 25/328 (7%)
Query: 95 PKNQLNKETDPVKSPPLPEHQKIPCNSAEPKSIPALSMET-QKLGSVLSPESPKPTPLTP 153
P T P+ + P + P + P + T + ++P TP+T
Sbjct: 3707 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3766
Query: 154 LEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEP-----PKSVPVCESQKLAPVPSPEPQ 208
P + QTP +P + +P P P + P+ + + P P+P
Sbjct: 3767 TTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3825
Query: 209 KPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWG-PSPAASPES 267
+ +P + T++ P P T P + ++ +P +P P G +P +P +
Sbjct: 3826 QTPTTTPITTTTTVT-PTPTPTGTQTPTTTPITTTTTVTP----TPTPTGTQTPTTTPIT 3880
Query: 268 RKSARTTSPEPR-KPSPSESPEPWKPFPAVSPEP-------RRPAPAVSPGSWKPGPPGS 319
+ T +P P +P+ +P +P P P + + P P G+
Sbjct: 3881 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3940
Query: 320 PRPWKSNPSASSGPWKPAKPAPSVSPGP-WKPIPSVSPGPWKPTPSVSSASWKSSSVSPS 378
P + P ++ P P P+ + P PI + + PTP+ + + ++ ++ +
Sbjct: 3941 QTP-TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTT 3997
Query: 379 SWKSPPASPESWKSGPPELRKTAPTLSP 406
+ +P +P ++ T T++P
Sbjct: 3998 TTVTPTPTPTGTQTPTTTPITTTTTVTP 4025
Score = 44.3 bits (103), Expect = 5e-04
Identities = 53/272 (19%), Positives = 108/272 (39%), Gaps = 28/272 (10%)
Query: 155 EPQKPGSVV----------SPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPS 204
E QKPG V+ + + + P + +P PP + P+ + + P P+
Sbjct: 1853 EDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPT 1912
Query: 205 PEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWG-PSPAA 263
P + +P + T++ P P T P + ++ +P +P P G +P
Sbjct: 1913 PTGTQTPTTTPITTTTTVT-PTPTPTGTQTPTTTPITTTTTVTP----TPTPTGTQTPTT 1967
Query: 264 SPESRKSARTTSPEPR-KPSPSESPEPWKPFPAVSPEP-------RRPAPAVSPGSWKPG 315
+P + + T +P P +P+ +P +P P P + + P
Sbjct: 1968 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2027
Query: 316 PPGSPRPWKSNPSASSGPWKPAKPAPSVSPGP-WKPIPSVSPGPWKPTPSVSSASWKSSS 374
P G+ P + P ++ P P P+ + P PI + + PTP+ + + ++
Sbjct: 2028 PTGTQTP-TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP 2084
Query: 375 VSPSSWKSPPASPESWKSGPPELRKTAPTLSP 406
++ ++ +P +P ++ T T++P
Sbjct: 2085 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2116
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 92.0 bits (227), Expect = 2e-18
Identities = 147/579 (25%), Positives = 220/579 (37%), Gaps = 84/579 (14%)
Query: 82 TSKHASPDKWNDKPKNQLNKET---DPVKSPPLPEHQKIPCNSAEPKS----IPALSMET 134
+S+ SP K K + ++T P SPP H+ P + PK+ P S T
Sbjct: 364 SSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRT 423
Query: 135 QKLGSVLSP--ESPKPTPLTPLEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVP 192
+K +SP S K T E + ++P P+P+P K +S E K
Sbjct: 424 RKSRVSVSPGRTSGKVTKHKGTEKR----------ESPSPAPKPRK-VELSESEEDKGGK 472
Query: 193 VCESQKLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAA 252
+ + + Q S ++ + +P K+SH G SP +A
Sbjct: 473 MAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERP-KRSHVKN--GEVGRRRRHSPSRSA 529
Query: 253 SPEPWGPSPAASPESRKSARTTSPEP--RKPSPSESPEPWKPFPAVSPEPRRPAPAVSPG 310
SP P SP R+ R+ SP P R+ SPS +P P + +P PRR P+ P
Sbjct: 530 SPSPRKRQKETSPRGRRR-RSPSPPPTRRRRSPSPAPPPRRR-RTPTPPPRRRTPSPPPR 587
Query: 311 SWKPGP-----------PGSPRPWKSNPSASSGPWKPAKPAPS----VSPGPWKPIPSVS 355
P P SP P + S P + A P+P VS P P S
Sbjct: 588 RRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSP-PPKQRSS 646
Query: 356 PGPWKPTPSVSSASWKSSSVSPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPV 415
P + +PS+SS K SS S S+ ++ P S P R + SP +
Sbjct: 647 PVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASS 706
Query: 416 SPELRKPGPPLSPEIRSPAGSPELR--KPSGSPDLWKLSPDQRKTSPASLDFPESQKSSR 473
SP+ R+ P + IR + +PE + K + SP SP S+ S +S
Sbjct: 707 SPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASP------------SPQSVRRVSSSRSV- 753
Query: 474 GGSPDLWKSSFFIEPQKPVFPETRK-PGPSGPSESPKAASDIWKPVLSIDTEPRKPALFP 532
GSP+ P +K P P P +S ++ S W P + P K A P
Sbjct: 754 SGSPE---------------PAAKKPPAPPSPVQS-QSPSTNWSPAV-----PVKKAKSP 792
Query: 533 EPAKTAPPASPE--ARKRALFPEPRKHALFPELPKSALFSESQKAVELGDELQIDAIDDQ 590
P+ + P S + K+ + +KH + K + + A
Sbjct: 793 TPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAA 852
Query: 591 KCDILVQEELLAS--PKKLLEDTLFPSSKKLKKDNQESS 627
L QEE +A+ PKK E + L+K +E +
Sbjct: 853 ATTTLAQEEPVAAPEPKKETESEAEDNLDDLEKHLREKA 891
Score = 78.6 bits (192), Expect = 2e-14
Identities = 120/533 (22%), Positives = 195/533 (36%), Gaps = 67/533 (12%)
Query: 101 KETDPVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKPTPLTPLEPQKPG 160
+ + PV+ H + P + + +S + +K +PE P+P+ +
Sbjct: 184 RRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEK-----TPELPEPSVKVKEPSVQEA 238
Query: 161 SVVSPELQTPLPS--PEPSKPASVSSPEP--------PKSVPVCESQKLAPVPSPEPQKP 210
+ S L+ P P PEP +P+ + + P+S +S+ SP +P
Sbjct: 239 TSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRP 298
Query: 211 --------APVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPV---------LAAS 253
SP + P P++++ PP SPV L+ S
Sbjct: 299 RRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGS 358
Query: 254 PEPWGPSPAASPESRKSARTTSP--EPRKPSPSESP--EPWKPFPAVSPEPR---RPAPA 306
S + SP + RT+SP + R+ SPS SP +P P +P P+ P P
Sbjct: 359 SSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQ 418
Query: 307 VSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSP-------------GPWKPIPS 353
S + K SP + G K P+P+ P G S
Sbjct: 419 QSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADS 478
Query: 354 VSPGPWKPTPSVSSASWKSSSVSPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVP 413
V + S+S SS S + + ++ + G + + SP K
Sbjct: 479 VQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQK 538
Query: 414 PVSP---ELRKPGPPLSPEIRSPAGSPELRK---PSGSPDLWKLSPDQRKTSPASLDF-P 466
SP R P PP + RSP+ +P R+ P+ P SP R+ SP+ + P
Sbjct: 539 ETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSP 598
Query: 467 ESQKSSRGGSPDLWKSSFFIEPQKPVFPETRKPGPSGPSESPKAASDIWKPVLSIDTEPR 526
Q+ P +++ P P R+ PS P + + S K S T+ R
Sbjct: 599 PIQRRYSPSPPPKRRTA------SPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRR 652
Query: 527 KPALFPEPAKTAPPASPEARKRALFPEPRKHALFPELPKSALFSESQKAVELG 579
P+L + K + P+ + + A P+P K P++ S S V G
Sbjct: 653 SPSLSSKHRKGSSPS--RSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRG 703
Score = 73.6 bits (179), Expect = 7e-13
Identities = 90/339 (26%), Positives = 135/339 (39%), Gaps = 66/339 (19%)
Query: 80 HITSKHASPDKWNDKPKNQLNKETDP------VKSPPLPEHQKIPCNSAEPKSIPALSME 133
H S+ ASP P+ + KET P SPP ++ P + P+ +
Sbjct: 523 HSPSRSASPS-----PRKR-QKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPP 576
Query: 134 TQKLGSVLSPE--SPKPTPLTPLEPQKPGSVVSPELQTPLPSPEPSKPASVSSPE----- 186
++ P SP P +P ++ P+ +T P P P + AS S P
Sbjct: 577 PRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVS 636
Query: 187 ---PPKSVPVCESQKLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSAS 243
PPK +++ +P S + +K + SP +P+P K+ H P +
Sbjct: 637 HSPPPKQRSSPVTKRRSPSLSSKHRKGS--SPSRSTREARSPQPNKR-HSP-------SP 686
Query: 244 SPESPVLAASPEPWGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVS--PEPR 301
P +P ++SP P ++SP+ R+S PSPS +P VS PEP+
Sbjct: 687 RPRAPQTSSSPPPVRRGASSSPQRRQS----------PSPST-----RPIRRVSRTPEPK 731
Query: 302 RPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGP-WK 360
+ A SP P S R S+ S S P +PA P P P+ S SP W
Sbjct: 732 KIKKAASPS------PQSVRRVSSSRSVSGSP----EPAAKKPPAPPSPVQSQSPSTNWS 781
Query: 361 PTPSVSSASWKSSSVSPSSWKSPPASPESWKSGPPELRK 399
P V A SP+ SPP + + G + +K
Sbjct: 782 PAVPVKKAK------SPTPSPSPPRNSDQEGGGKKKKKK 814
Score = 72.0 bits (175), Expect = 2e-12
Identities = 100/418 (23%), Positives = 148/418 (35%), Gaps = 72/418 (17%)
Query: 204 SPEPQK-PAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPA 262
SP P++ +PV E ++ +P+ + +S P +PE P PS
Sbjct: 179 SPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPE---------PSVK 229
Query: 263 ASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPE---------PRRPAPAVSPGSWK 313
S + A +TS + P P PEP +P P + + PR + + S +
Sbjct: 230 VKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTR 289
Query: 314 PGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTP---------- 363
P RP + + S S +P+P P P + P P P P
Sbjct: 290 SRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTP---PRRMPPPPRHRRSRSPVR 346
Query: 364 ----SVSSASWKSSSVSPSSWKSPPASPESWKSGPP-ELRKTAPTLSP--EHWKAVPPVS 416
S +S S SSS S S +SPP P S PP + R+ +P+ SP + PP +
Sbjct: 347 RRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPAT 406
Query: 417 PELR---KPGPPLSPEIRSPAGSPELRKPSGSPDLWKLSPDQRKTSPA------SLDFPE 467
P + P P S R S + SG K + + SPA L E
Sbjct: 407 PPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESE 466
Query: 468 SQKSSRGGSPDLWKSSFFIEPQKPVFPETRKPGPSGPSESPKAA----SDIWK-----PV 518
K + + D + Q S E PK + ++ + P
Sbjct: 467 EDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPS 526
Query: 519 LSIDTEPRK--------------PALFPEPAKTAP-PASPEARKRALFPEPRKHALFP 561
S PRK P+ P + +P PA P R+R P PR+ P
Sbjct: 527 RSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSP 584
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 91.3 bits (225), Expect = 3e-18
Identities = 99/366 (27%), Positives = 139/366 (37%), Gaps = 44/366 (12%)
Query: 124 PKSIPALSMETQKLGSVLSPESPKPTPLTPLEPQKPGSVVSPELQTPLPSPEPSKPA--- 180
P+ P LG + S P+P P P P P LQT LPSP + P+
Sbjct: 274 PQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAP-----PSLQT-LPSPPATPPSQAT 327
Query: 181 -SVSSPEPPKSVPVCESQKLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGP 239
S+ SP + S L+P+ +P PQ P ++ ++A S P S L
Sbjct: 328 TSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLS----PLAT 383
Query: 240 PSASSPESPVLAASPEPWGPSPAASPESRKSARTTSP-EPRKPSPSESPEPWKPFPAVSP 298
PS +P + + P+ P P+ ++ S + P P PS++P P A P
Sbjct: 384 PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP----PSLAAPP 439
Query: 299 EPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGP 358
P+P SP P P + P ++ P ++ P + AKP P P P P
Sbjct: 440 LQVPPSPPASP----PMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATP-----PLQ 490
Query: 359 WKPTPSVSSASWKSSSVSPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPE 418
P+P S S S S SP A+P PP L + P PP SP
Sbjct: 491 ALPSPPASFPGQAPFSPSASLPMSPLATPP--PQAPPVLAAPLLQVPPS-----PPASPT 543
Query: 419 LRKPGPPLSPEIRSPAGSPELR---------KPSGSPDLWKLSPDQRKTSPASLDFPESQ 469
L+ P P +P + P L PS SP PD S ++ PE
Sbjct: 544 LQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEEL 603
Query: 470 KSSRGG 475
+ G
Sbjct: 604 RGYDSG 609
Score = 81.6 bits (200), Expect = 3e-15
Identities = 90/341 (26%), Positives = 133/341 (39%), Gaps = 39/341 (11%)
Query: 105 PVKSPPLPEHQK--IPCNSAEPKSIPALSMETQKLGSVLSPESPKPTPLT-----PLEP- 156
P+++PP P P + P++ AL++ + P P P + P+ P
Sbjct: 365 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 424
Query: 157 -----QKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQ--K 209
Q P S+ +P LQ P PSP S P S S+ PP++ P P+ +P Q K
Sbjct: 425 ATPPSQAPPSLAAPPLQVP-PSPPASPPMSPSATPPPQAPP--------PLAAPPLQLAK 475
Query: 210 PAPVSPESVKATLSNPKPQKQSHFP-ETLGPPSASSPESPVLAASPEPWGPSPAASPESR 268
P P +P ++ P + FP + PSAS P SP+ A+P P P A+P
Sbjct: 476 PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAP--- 530
Query: 269 KSARTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPS 328
+ P P+ P P P S R A++PG P P SP S P
Sbjct: 531 -LLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP-PPPPSRSPSSTLSGPD 588
Query: 329 A---SSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPPA 385
SS + GP + + SP P + A+W P +++ P
Sbjct: 589 LAGHSSSATSTPEELRGYDSGP-EGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPG 647
Query: 386 SPESW--KSGPPELRKTAPTLSPEHWKAVPPVSPELRKPGP 424
+P W +GP E ++ P +P PGP
Sbjct: 648 APLPWPPATGPGSADGLCTIYETEGPESATP-APGALDPGP 687
Score = 79.0 bits (193), Expect = 2e-14
Identities = 118/437 (27%), Positives = 158/437 (36%), Gaps = 49/437 (11%)
Query: 143 PESPKPTPLTPLEPQKPGSVVSPELQ--TPLPSPEPSKPASVSSPEPPKSVPVCESQKLA 200
P S + P + PG V SP T P P K +S+ E E+ K +
Sbjct: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145
Query: 201 PVPS--------PEPQKPAPVSPESVKAT-----LSNPKPQKQSHFPETLGPPSASSPES 247
+ + P P P+P +A L P P + P T GP + S S
Sbjct: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPR-PPTEGPRKSVSSAS 204
Query: 248 PVLAASPEPWG---PSPAAS---PESRKSARTTSP--EPRKPSPSESPEPWKPFPAVSPE 299
P P PS P SR + + +P P + PS P P P+
Sbjct: 205 EHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPK 264
Query: 300 PRRPAPAVSPGSWKPGPPGSPR--PWKSNPSASSGPWKPAKPAPSVSPG-PWKPIPSVSP 356
P+ P P +P P S+P A+ P P P+PS P P P +P
Sbjct: 265 PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAP--PSPSAPPSLQTLPSPPATP 322
Query: 357 GPWKPTPSVSSASWKSS-SVSPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPV 415
P + T S+ S + +++ S PS SP A+P PP L P +P A PP+
Sbjct: 323 -PSQATTSLGSPTLQATHSFLPSPPLSPLATPP--PQAPPAL-ALPPLQAPPSPPASPPL 378
Query: 416 SPELRKPGPPLSPEIR--------SPAGSPELRKPSGSPDLWKLSPDQRKTS--PASLDF 465
SP L P P + SP SP ++ P P +SP S P SL
Sbjct: 379 SP-LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA 437
Query: 466 PESQKSSRGGSPDLWKSSFFIEPQKPVFPETRKPGPSGPSESPKAASDIWKPVLSIDTEP 525
P Q + S PQ P P P P+A + P L P
Sbjct: 438 PPLQVPPSPPASPPMSPSATPPPQAP--PPLAAPPLQLAKPPPQAPPALATPPL--QALP 493
Query: 526 RKPALFPEPAKTAPPAS 542
PA FP A +P AS
Sbjct: 494 SPPASFPGQAPFSPSAS 510
Score = 78.6 bits (192), Expect = 2e-14
Identities = 112/412 (27%), Positives = 159/412 (38%), Gaps = 62/412 (15%)
Query: 199 LAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWG 258
L P P P+ P PV+P +++ + ++ G A+ PES A
Sbjct: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSR 84
Query: 259 PSPAASPESRKSARTTSPEPRKPSPSESPEPWKPFP------AVSPE-----------PR 301
P + E A+ TSP P SP + +P P +S E P+
Sbjct: 85 PPASGRGERAPPAKNTSPGP-VSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPK 143
Query: 302 RPAPAVSPGSWKPGP-PGSPRPWKSNPSASSGPWKP-AKPAPSVSP-----GPWKPIPSV 354
R A + GP PG+P P + S ++G +PAPS P GP K + S
Sbjct: 144 RSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSA 203
Query: 355 S------PGP-WKPTPSVSSASWKSSSVSPSSWKSPPASPESWKSGP-----PELRKTAP 402
S P P + PS + +S S SS +P +SP +SGP P
Sbjct: 204 SEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA--RSGPSARGTPRAPAHPS 261
Query: 403 TLSPEHWKAV--PPVSPELRKPGPPLSPEIRSPAGSPELRKPSGSPDLWKLSPDQRKTSP 460
P+ +A+ P V+P + P L P SP +P PS P +P +T P
Sbjct: 262 QPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATP---SPSAPPS--PSAPPSLQTLP 316
Query: 461 ASLDFPESQKSSRGGSPDLWKSSFFIEPQKPVFPETRKPGPSGPSESPKAASDIWKPVLS 520
+ P SQ ++ GSP L + F+ P P+ P P P P A P+ +
Sbjct: 317 SPPATPPSQATTSLGSPTLQATHSFL-PSPPLSPLATPP----PQAPPALA---LPPLQA 368
Query: 521 IDTEPRKPALFP--EPAKTAPPASPEARKRALFPEPRKHALFPELPKSALFS 570
+ P P L P P+ AP A +A F P P P A FS
Sbjct: 369 PPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP------PSPPVQAPFS 414
Score = 75.1 bits (183), Expect = 2e-13
Identities = 120/464 (25%), Positives = 166/464 (35%), Gaps = 80/464 (17%)
Query: 143 PESPKPTP-LTPLEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAP 201
P SP+P P +TP + G+ + + PL + P++ P S+ A
Sbjct: 30 PGSPRPPPPVTPAALRVLGAAGAVG-RKPLAERAGGIGGATIPESAPRAGPTRTSRPPAS 88
Query: 202 -----VPSPEPQKPAPVSPESVKATLSNPKPQKQSHF----PETLGPPSAS-SPESPVLA 251
P + P PVS + + P P Q ET+ A+ +P+ L+
Sbjct: 89 GRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALS 148
Query: 252 AS-------PEPWGPSPAASPESRKSARTTSPEPRKPSPSESPEP--------------- 289
A P P PSPA + SR +A T PR P+PS P P
Sbjct: 149 AGARRDTSGPTPGTPSPAMARRSR-AAGTEVGLPR-PAPSARPRPPTEGPRKSVSSASEH 206
Query: 290 --WKPFPAVSPEPRRPAPAVSPGSWKPGPPGSP--RPWKSNPSASSGPWKPAKPA----- 340
+P PA P P S +P P +S PSA P PA P+
Sbjct: 207 STTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPK 266
Query: 341 -------PSVSPGPWKPIPSVSPGPWKP--TPSVSSASWKSSSVSPSSWKSPPASPESWK 391
P V+P P++ P P TPS S+ S+ S + SPPA+P S
Sbjct: 267 GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQA 326
Query: 392 SGPPELRKTAPTLSPEH-WKAVPPVSPELRKPGPPLSPEIRSPAGSPELRKPSGSPDLWK 450
+ +PTL H + PP+SP L P P P + P L+ P P
Sbjct: 327 T----TSLGSPTLQATHSFLPSPPLSP-LATPPPQAPPAL----ALPPLQAPPSPPASPP 377
Query: 451 LSPDQRKTSPASLDFPESQKSSRGGSPDLWKSSFFIEPQKPVFPETRKPGPSGPSESPKA 510
LSP L P Q + + L ++ F P PV P P SP
Sbjct: 378 LSP---------LATPSPQ-APNALAVHLLQAPFSPPPSPPV------QAPFSPPASPPV 421
Query: 511 ASDIWKPVLSIDTEPRKPALFPEPAKTAPPASPEARKRALFPEP 554
+ P + + P P +PP SP A P P
Sbjct: 422 SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 465
Score = 61.2 bits (147), Expect = 4e-09
Identities = 81/324 (25%), Positives = 113/324 (34%), Gaps = 75/324 (23%)
Query: 85 HASPDKWNDKPKNQLNKETDPVKSPPL-----PEHQKIPCNSAEPKSIPALSMETQKLGS 139
H ++ P + P SPP+ P Q P +A P +P + +
Sbjct: 395 HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 454
Query: 140 VLSPESPKPTPLT--PLEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQ 197
+P P PL PL+ KP P L TP PS PAS P S
Sbjct: 455 SATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP---FSPSASL 511
Query: 198 KLAPVPSPEPQKPAPVSPESVKATLSNP-KPQKQS-HFPETLGPPSASSPESPVLAASPE 255
++P+ +P PQ P ++ ++ S P P Q+ P T GP ++ S LA +P
Sbjct: 512 PMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG 571
Query: 256 PWGPSPAASPES---------RKSARTTSPEP---------------------------- 278
P P P+ SP S S+ T++PE
Sbjct: 572 P-PPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPA 630
Query: 279 ---RKPSPS-------ESPEPWKP-------------FPAVSPEPRRPAP-AVSPGSWKP 314
R P+P +P PW P + PE PAP A+ PG P
Sbjct: 631 AWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGP-SP 689
Query: 315 GPPGSPRPWKSNPSASSGPWKPAK 338
G G + ASS K A+
Sbjct: 690 GTSGGKAAAGAGAGASSRSPKQAR 713
Score = 40.4 bits (93), Expect = 0.007
Identities = 80/345 (23%), Positives = 112/345 (32%), Gaps = 72/345 (20%)
Query: 301 RRPAPAVSPGSWKPGPPGSPR--------------------------------------- 321
R PA A +PG P PPGSPR
Sbjct: 15 RTPA-ARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPES 73
Query: 322 -----PWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVS 376
P +++ +SG + A PA + SPGP P + G +P P S+ +
Sbjct: 74 APRAGPTRTSRPPASGRGERAPPAKNTSPGPVSS-PGRASGTTRPGPLGQKGLRISAEET 132
Query: 377 PSSWKSPPASPESWKSGPPELRKTAP---TLSPEHWKAVPPVSPELRKPGPPLSPEIRSP 433
+ K+ A S S + P T SP + E+ P P S R P
Sbjct: 133 VARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP 192
Query: 434 AGSPELRKPSGSP-DLWKLSPDQRKTSPA--SLDFPESQKSSRG----GSPDLWKSSFFI 486
P S S + SP R+ A L P S+ S SP S
Sbjct: 193 TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARG 252
Query: 487 EPQKPVFPETRKP------GPSGPSESPKAASDIWKPVLSIDTEPRKPALFPEPAK---- 536
P+ P P KP P + K A+ P+ S P+ P P+
Sbjct: 253 TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSL 312
Query: 537 ---TAPPASPEARKRALFPEP---RKHALFPELPKSALFSESQKA 575
+PPA+P ++ P H+ P P S L + +A
Sbjct: 313 QTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA 357
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 87.8 bits (216), Expect = 4e-17
Identities = 112/408 (27%), Positives = 155/408 (37%), Gaps = 65/408 (15%)
Query: 139 SVLSPESPKPTPLTPLEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQK 198
+V +PE P + P++P S P P P S A+V +PE P S
Sbjct: 980 TVHAPEEPDTAAVRVSTPEEPAS---PAAAVPTPEEPTSPAAAVPTPEEPTS-------P 1029
Query: 199 LAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWG 258
A VP PE P SP + T P P+ P SP AA P P
Sbjct: 1030 AAAVPPPE----EPTSPAAAVPTPEEPT-------SPAAAVPTPEEPTSPA-AAVPTPEE 1077
Query: 259 P-SPAASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPP 317
P SPAA+ + + TSP P+P E P P EP PA AV P +P P
Sbjct: 1078 PTSPAAAVPTPE--EPTSPAAAVPTPEEPTSPAAAVP-TPEEPASPAAAV-PTPEEPASP 1133
Query: 318 GSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIP----SVSPGPWKPTPSVSSASWKSS 373
+ P P+ + PA P P S +P S SP PTP+ SAS+ +
Sbjct: 1134 AAAVPTPEEPAFPA----PAVPTPEESASAAVAVPTPEESASPAAAVPTPA-ESASFAAV 1188
Query: 374 SVSPSSWKSPPASPESWKSGPPELRK-TAPTLSPEHWKAVPPVSPELRKPGPPLSPEIRS 432
+ SP AS + + L + T+P S + ++ + P P SP
Sbjct: 1189 VATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSP---- 1244
Query: 433 PAGSPELRKPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGSPDLWKSSFFIEPQKPV 492
A P L +P+ S L+P++ + AS+ PE EP P
Sbjct: 1245 AAAVPTLEEPTSSAAA-VLTPEELSSPAASVPTPE-------------------EPASPA 1284
Query: 493 FPETRKPGPSGPSESPKAASDIWKPVLSIDTEPRKPALFPEPAKTAPP 540
+ P+ P+ + P S+ T P PA+ PA PP
Sbjct: 1285 AAVSNLEEPASPAAAVPTPEVAAIPAASVPT-PEVPAI---PAAAVPP 1328
>gi|31324577 molecule interacting with Rab13 [Homo sapiens]
Length = 863
Score = 87.4 bits (215), Expect = 5e-17
Identities = 153/644 (23%), Positives = 231/644 (35%), Gaps = 81/644 (12%)
Query: 108 SPPLPEHQKIPCNSAE------PKSIPALSMETQKLGSVLSPESPKPTPLTPLEPQKPGS 161
S P +HQ+ A+ P S E G SPE+ P P P K
Sbjct: 235 SQPKQQHQQQLAEDAKDVPGGGPSSSAPAGAEAD--GPKASPEARPQIPTKPRVPGKLQE 292
Query: 162 VVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQKPAPVSPESVKAT 221
+ SP P P+P + ++ +P P+ + + L + V
Sbjct: 293 LASPPAGRPTPAPRKASESTTPAPPTPRPRSSLQQENLVEQAGSSSLVNGRLHELPVPKP 352
Query: 222 LSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPA-ASPESRKSARTTSPEPRK 280
PKP + + P P P +P P SP S +SR+ + E +
Sbjct: 353 RGTPKPSEGTPAPRKDPPWITLVQAEPKKKPAPLPPSSSPGPPSQDSRQVENGGTEEVAQ 412
Query: 281 PSPSESPE--PWKPFPAVSPE-----PRRPAPAVSPGSWKP-GPPGSPRPWKSNPSASSG 332
PSP+ S E P+ PF + P P+ A SP P P S PW SS
Sbjct: 413 PSPTASLESKPYNPFEEEEEDKEEEAPAAPSLATSPALGHPESTPKSLHPWYGITPTSSP 472
Query: 333 PWK--PAKPAPSVSP--------GPWKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKS 382
K PA APS SP +P PS +P P S+SS S +S + +
Sbjct: 473 KTKKRPAPRAPSASPLALHASRLSHSEP-PSATPSPALSVESLSSES--ASQTAGAELLE 529
Query: 383 PPASPESWKS---------GPPELRKTAPTLSPEHWKAVPPVSPELRKPGPPLSPEIRSP 433
PPA P+S G P T +L+ + V P ++ + P L+P R
Sbjct: 530 PPAVPKSSSEPAVHAPGTPGNPVSLSTNSSLA-SSGELVEPRVEQMPQASPGLAPRTRGS 588
Query: 434 AGSPELRKPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGSPDLWKSSFFIEPQKPVF 493
+G + SG+ L R P S SP L S E
Sbjct: 589 SGPQPAKPCSGATPTPLLLVGDRSPVP----------SPGSSSPQLQVKSSCKEN----- 633
Query: 494 PETRKPGPSGPSESPKAASDIWKPVLSIDTEPRKPALFPEPAKTAPPASPEARKRALFPE 553
P RKP P+ + KA T+ KP P P P + + PE
Sbjct: 634 PFNRKPSPAASPATKKA------------TKGSKPVRPPAPGHGFPLIKRKVQADQYIPE 681
Query: 554 PRKHALFPELPKSALFSESQKAVELGDELQIDAIDDQKCDILVQEELLASPKKLLEDTLF 613
H + + L + + V L ++L+ + ++ D+LV L K LL
Sbjct: 682 EDIHGEMDTIER-RLDALEHRGVLLEEKLRGGLNEGREDDMLVDWFKLIHEKHLLVRRES 740
Query: 614 PSSKKLKKDNQESSDAELSSSEY-IKTDLDAMDIKGQESSSDQEQVDVESIDFSKENK-- 670
K+ N E A++ EY ++ L+ + E +E+V ++ + E +
Sbjct: 741 ELIYVFKQQNLEQRQADV---EYELRCLLNKPEKDWTEEDRAREKVLMQELVTLIEQRNA 797
Query: 671 ------MDMTSPEQSRNVLQFTEEKEAFISEEEIAKYMKRGKGK 708
D E+ +L+ +K+ F E E + K+GK K
Sbjct: 798 IINCLDEDRQREEEEDKMLEAMIKKKEFQREAE-PEGKKKGKFK 840
Score = 77.0 bits (188), Expect = 6e-14
Identities = 100/398 (25%), Positives = 142/398 (35%), Gaps = 103/398 (25%)
Query: 102 ETDPVKSPPLPEHQKIPCNSAEPKSIPA--LSMETQKLGSVLSPESPKPTPLTPLEPQK- 158
+ P P +P ++P E S PA + +K +P P P P + L+ +
Sbjct: 271 KASPEARPQIPTKPRVPGKLQELASPPAGRPTPAPRKASESTTPAPPTPRPRSSLQQENL 330
Query: 159 -----PGSVVSPEL-QTPLPSPEPSKPASVSSPEPPKSVP----VCESQKLAPVPSPEPQ 208
S+V+ L + P+P P + S +P P K P V K P P P
Sbjct: 331 VEQAGSSSLVNGRLHELPVPKPRGTPKPSEGTPAPRKDPPWITLVQAEPKKKPAPLPPSS 390
Query: 209 KPAPVSPESVKAT------LSNPKP------QKQSHFPETLGPPSASSPESPVLAASP-- 254
P P S +S + ++ P P + + F E +P +P LA SP
Sbjct: 391 SPGPPSQDSRQVENGGTEEVAQPSPTASLESKPYNPFEEEEEDKEEEAPAAPSLATSPAL 450
Query: 255 ----------EPW-GPSPAASPESRKSARTTSPEPRKPSPS-----------ESPEPWKP 292
PW G +P +SP+++K P PR PS S P P
Sbjct: 451 GHPESTPKSLHPWYGITPTSSPKTKKR-----PAPRAPSASPLALHASRLSHSEPPSATP 505
Query: 293 FPAVSPE------------------PRRPAPAVSPGSWKPGPPGSPRPWKSNPS------ 328
PA+S E P P + P PG PG+P +N S
Sbjct: 506 SPALSVESLSSESASQTAGAELLEPPAVPKSSSEPAVHAPGTPGNPVSLSTNSSLASSGE 565
Query: 329 ---------------------ASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSS 367
SSGP +PAKP +P P + SP P + S
Sbjct: 566 LVEPRVEQMPQASPGLAPRTRGSSGP-QPAKPCSGATPTPLLLVGDRSPVPSPGSSSPQL 624
Query: 368 ASWKSSSVSPSSWK-SPPASPESWKS--GPPELRKTAP 402
S +P + K SP ASP + K+ G +R AP
Sbjct: 625 QVKSSCKENPFNRKPSPAASPATKKATKGSKPVRPPAP 662
>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 86.7 bits (213), Expect = 8e-17
Identities = 125/458 (27%), Positives = 164/458 (35%), Gaps = 86/458 (18%)
Query: 170 PLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSP---EPQKPAPVS--PESVKATLSN 224
P P P P P +S EPP P+ AP P P EP P ++ P V LS
Sbjct: 142 PPPGPAPGPPQDIS--EPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSP 199
Query: 225 PKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPAASPESRKSARTTSPEPRKPSPS 284
P P PP P P+ +P P P PA +P + S T + P
Sbjct: 200 PHTLSSPSIPT---PPDFIPPAPPLAFLAPPP-PPVPAPAPPAPASPHTVG---TRLFPP 252
Query: 285 ESPEPWKPFPAVS---PEPRRPAPAVSPGSWKPGPPGS--------PRPWKSNP----SA 329
WK A++ E R +P SP K G PR +K P
Sbjct: 253 GGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRT 312
Query: 330 SSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPPASPES 389
SS P + A+ AP G K PS P P S + P+S P +PE
Sbjct: 313 SSIPVQEAQEAPRKEEGATKKAPSRLPLP------------PSFHIRPASQVYPDRAPE- 359
Query: 390 WKSGPPELRKTAPTLSP---------EHWKAVPPVSPELRKPGPPLSPEIRSPAGSPELR 440
P EL+ TAP SP + PP +P L P PPL P P
Sbjct: 360 -PDCPGELKATAPA-SPRLGQSQSQADERAGTPPPAPPLPPPAPPLPP--------PAPP 409
Query: 441 KPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGSPDLWKSSFFIEPQKPVFPETRKPG 500
P +P L P +K + F ++ KSS SP L +P P T
Sbjct: 410 LPPAAPPL----PCAQKAAHPPAGFTKTPKSS---SPALKP-----KPNPPSPENTASSA 457
Query: 501 P---SGPSESPKAASDIWKPVLSIDTEPRKPALFPEPAKTAPPASPEARKRALFPE---- 553
P PS+ K +++ + E R L P T P S E +K PE
Sbjct: 458 PVDWRDPSQMEKLRNELAAYLCGSRREDR--FLSHRPGPTVAPQSKEGKKGPRLPEKETL 515
Query: 554 ---PRKHALFPELPKSALFSESQKAVELGDELQIDAID 588
P K P +P+ +L S E L + ++D
Sbjct: 516 LSLPAKDTP-PGVPEKSLGGSSLTETEAAPSLTLPSVD 552
Score = 85.9 bits (211), Expect = 1e-16
Identities = 151/636 (23%), Positives = 220/636 (34%), Gaps = 121/636 (19%)
Query: 103 TDPVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKPTPLTPLEPQKPGSV 162
++P PLP P ++A P P L +E S+ P P L+P P ++
Sbjct: 155 SEPPGGSPLPS----PPSTAPPP--PPLLLEPPPPPSMAPPPPPVLEALSP-----PHTL 203
Query: 163 VSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQKPAPVSPESVKATL 222
SP + TP P+ P + +P PP PVP+P P PAP SP +V L
Sbjct: 204 SSPSIPTPPDFIPPAPPLAFLAPPPP------------PVPAPAP--PAPASPHTVGTRL 249
Query: 223 SNP-----------KPQKQSHFPETLGPPSASSPESPVLAASPEPW--------GPSPAA 263
P +Q+ P S + P+ L +PEP P P
Sbjct: 250 FPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTP 309
Query: 264 SPESRKSARTTSPEPRK--------PSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPG 315
S + PRK PS P + PA P R PG K
Sbjct: 310 VRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKAT 369
Query: 316 PPGSPRPWKSNPSAS--SGPWKPAKPAPSVS---PGPWKPIPSVS------------PGP 358
P SPR +S A +G PA P P + P P P+P + P
Sbjct: 370 APASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAG 429
Query: 359 WKPTPSVSSASWKSSSVSPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPE 418
+ TP SS + K PS + ++P W+ P ++ K L+ +
Sbjct: 430 FTKTPKSSSPALKPKPNPPSPENTASSAPVDWRD-PSQMEKLRNELAAYLCGSRREDRFL 488
Query: 419 LRKPGPPLSPEIRSPAGSPELRKPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGS-- 476
+PGP ++P+ + P L P+ L K +P P + S GGS
Sbjct: 489 SHRPGPTVAPQSKEGKKGPRL------PEKETLLSLPAKDTP-----PGVPEKSLGGSSL 537
Query: 477 ------PDLWKSSFFIEPQKPVFPETRKPGPSGPSESPKAASDIWKPVLSIDTEPRKPAL 530
P L S PQ P R+ + AA KP SI + P KP L
Sbjct: 538 TETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKP--SIGSLPPKPRL 595
Query: 531 ----------------------FPEPAKTAPPASPEARKRALFPE-PRKHALFPEL-PKS 566
P + T P + K L P P K P + PK+
Sbjct: 596 EGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKA 655
Query: 567 ALFSESQKAVELGDELQIDAIDDQKCDI-LVQEELLASPKKLLEDTLFPSSKKLKKDNQE 625
L+ + LG + A + +AS L T S +KD+
Sbjct: 656 TLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTT--TSQLMAEKDSGP 713
Query: 626 SSDAELSSSEYIKTDLDAMDIKGQESSSDQEQVDVE 661
+ E +S+ + T A +G+ S S+ ++ +
Sbjct: 714 AGQPEKPASQEVSTPSQA---RGEGSPSEATRLPTQ 746
Score = 40.0 bits (92), Expect = 0.009
Identities = 67/310 (21%), Positives = 106/310 (34%), Gaps = 47/310 (15%)
Query: 105 PVKSPP----LPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKPTPLTPLEPQKPG 160
P K+ P +P K C+ + A+ M T G P P P P KP
Sbjct: 755 PPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPP 814
Query: 161 SVVSPE---LQTPLP-------SPEPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQKP 210
+ P L+ P+ SP A+ + +SV + P +
Sbjct: 815 ASAQPTDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQ 874
Query: 211 APVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPAASPESRKS 270
A S +S+ + P + F P + +SP+ P WGP E +
Sbjct: 875 AEASSDSIFHSQGTP-----NSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTEL 929
Query: 271 ART---TSPEPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNP 327
+R T PEP ++P W+ V+P + G P P+ + S P
Sbjct: 930 SRRHNWTKPEP------QAPVAWE--------------RVAPSNLPQGHP-LPKSFSSPP 968
Query: 328 SASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPPASP 387
S S+ K + + P P S P P P++ + SS +++ P
Sbjct: 969 SPSN---KREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLG-RQSSPPRNNYSDLRQLP 1024
Query: 388 ESWKSGPPEL 397
+ PP L
Sbjct: 1025 NAGPGAPPAL 1034
Score = 37.7 bits (86), Expect = 0.043
Identities = 74/341 (21%), Positives = 115/341 (33%), Gaps = 43/341 (12%)
Query: 118 PCNSAEPKSIPALSMETQKLGSVLSPESPKPTPLTPLEPQKP-GSVVSPELQTPLPSPEP 176
P + S P ++ ++ S + PT + L +K G PE P
Sbjct: 669 PATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTP 728
Query: 177 SKPASVSSPEPPKSVPVCESQKLAPVPSPEP----QKPAPVSPESVKATLSNPKPQKQSH 232
S+ SP +P ++ A P + P P +++LS ++ +
Sbjct: 729 SQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLS----REVAV 784
Query: 233 FPETLGPPSASSPESPVLAASPEPWGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKP 292
TL A+ P PV P P A P + SA+ T R P E E P
Sbjct: 785 VMPTLARGGAAGPGEPVEVKEP----PGLPAKPPA--SAQPTDELLRHPVTGEVVERGSP 838
Query: 293 FPAVSPEPRRPAPAVSPGS--WKPGPPGSPRPWKSNPSASSGPWKPAKPAPS---VSPGP 347
+ +R S G+ + PGS R ASS ++ P+ V P
Sbjct: 839 MALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKL 898
Query: 348 WK------PIPSVSPGPWKP--------TPSVSSASW-KSSSVSPSSWKSPPAS------ 386
K P+ + P W P T +W K +P +W+ S
Sbjct: 899 PKEAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGH 958
Query: 387 --PESWKSGPPELRKTAPTLSPEHWKAVPPVSPELRKPGPP 425
P+S+ S P K +++ +PP P PP
Sbjct: 959 PLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPP 999
>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 86.7 bits (213), Expect = 8e-17
Identities = 125/458 (27%), Positives = 164/458 (35%), Gaps = 86/458 (18%)
Query: 170 PLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSP---EPQKPAPVS--PESVKATLSN 224
P P P P P +S EPP P+ AP P P EP P ++ P V LS
Sbjct: 142 PPPGPAPGPPQDIS--EPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSP 199
Query: 225 PKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPAASPESRKSARTTSPEPRKPSPS 284
P P PP P P+ +P P P PA +P + S T + P
Sbjct: 200 PHTLSSPSIPT---PPDFIPPAPPLAFLAPPP-PPVPAPAPPAPASPHTVG---TRLFPP 252
Query: 285 ESPEPWKPFPAVS---PEPRRPAPAVSPGSWKPGPPGS--------PRPWKSNP----SA 329
WK A++ E R +P SP K G PR +K P
Sbjct: 253 GGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRT 312
Query: 330 SSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPPASPES 389
SS P + A+ AP G K PS P P S + P+S P +PE
Sbjct: 313 SSIPVQEAQEAPRKEEGATKKAPSRLPLP------------PSFHIRPASQVYPDRAPE- 359
Query: 390 WKSGPPELRKTAPTLSP---------EHWKAVPPVSPELRKPGPPLSPEIRSPAGSPELR 440
P EL+ TAP SP + PP +P L P PPL P P
Sbjct: 360 -PDCPGELKATAPA-SPRLGQSQSQADERAGTPPPAPPLPPPAPPLPP--------PAPP 409
Query: 441 KPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGSPDLWKSSFFIEPQKPVFPETRKPG 500
P +P L P +K + F ++ KSS SP L +P P T
Sbjct: 410 LPPAAPPL----PCAQKAAHPPAGFTKTPKSS---SPALKP-----KPNPPSPENTASSA 457
Query: 501 P---SGPSESPKAASDIWKPVLSIDTEPRKPALFPEPAKTAPPASPEARKRALFPE---- 553
P PS+ K +++ + E R L P T P S E +K PE
Sbjct: 458 PVDWRDPSQMEKLRNELAAYLCGSRREDR--FLSHRPGPTVAPQSKEGKKGPRLPEKETL 515
Query: 554 ---PRKHALFPELPKSALFSESQKAVELGDELQIDAID 588
P K P +P+ +L S E L + ++D
Sbjct: 516 LSLPAKDTP-PGVPEKSLGGSSLTETEAAPSLTLPSVD 552
Score = 85.9 bits (211), Expect = 1e-16
Identities = 151/636 (23%), Positives = 220/636 (34%), Gaps = 121/636 (19%)
Query: 103 TDPVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKPTPLTPLEPQKPGSV 162
++P PLP P ++A P P L +E S+ P P L+P P ++
Sbjct: 155 SEPPGGSPLPS----PPSTAPPP--PPLLLEPPPPPSMAPPPPPVLEALSP-----PHTL 203
Query: 163 VSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQKPAPVSPESVKATL 222
SP + TP P+ P + +P PP PVP+P P PAP SP +V L
Sbjct: 204 SSPSIPTPPDFIPPAPPLAFLAPPPP------------PVPAPAP--PAPASPHTVGTRL 249
Query: 223 SNP-----------KPQKQSHFPETLGPPSASSPESPVLAASPEPW--------GPSPAA 263
P +Q+ P S + P+ L +PEP P P
Sbjct: 250 FPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTP 309
Query: 264 SPESRKSARTTSPEPRK--------PSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPG 315
S + PRK PS P + PA P R PG K
Sbjct: 310 VRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKAT 369
Query: 316 PPGSPRPWKSNPSAS--SGPWKPAKPAPSVS---PGPWKPIPSVS------------PGP 358
P SPR +S A +G PA P P + P P P+P + P
Sbjct: 370 APASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAG 429
Query: 359 WKPTPSVSSASWKSSSVSPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPE 418
+ TP SS + K PS + ++P W+ P ++ K L+ +
Sbjct: 430 FTKTPKSSSPALKPKPNPPSPENTASSAPVDWRD-PSQMEKLRNELAAYLCGSRREDRFL 488
Query: 419 LRKPGPPLSPEIRSPAGSPELRKPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGS-- 476
+PGP ++P+ + P L P+ L K +P P + S GGS
Sbjct: 489 SHRPGPTVAPQSKEGKKGPRL------PEKETLLSLPAKDTP-----PGVPEKSLGGSSL 537
Query: 477 ------PDLWKSSFFIEPQKPVFPETRKPGPSGPSESPKAASDIWKPVLSIDTEPRKPAL 530
P L S PQ P R+ + AA KP SI + P KP L
Sbjct: 538 TETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKP--SIGSLPPKPRL 595
Query: 531 ----------------------FPEPAKTAPPASPEARKRALFPE-PRKHALFPEL-PKS 566
P + T P + K L P P K P + PK+
Sbjct: 596 EGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKA 655
Query: 567 ALFSESQKAVELGDELQIDAIDDQKCDI-LVQEELLASPKKLLEDTLFPSSKKLKKDNQE 625
L+ + LG + A + +AS L T S +KD+
Sbjct: 656 TLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTT--TSQLMAEKDSGP 713
Query: 626 SSDAELSSSEYIKTDLDAMDIKGQESSSDQEQVDVE 661
+ E +S+ + T A +G+ S S+ ++ +
Sbjct: 714 AGQPEKPASQEVSTPSQA---RGEGSPSEATRLPTQ 746
Score = 40.0 bits (92), Expect = 0.009
Identities = 67/310 (21%), Positives = 106/310 (34%), Gaps = 47/310 (15%)
Query: 105 PVKSPP----LPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKPTPLTPLEPQKPG 160
P K+ P +P K C+ + A+ M T G P P P P KP
Sbjct: 755 PPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPP 814
Query: 161 SVVSPE---LQTPLP-------SPEPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQKP 210
+ P L+ P+ SP A+ + +SV + P +
Sbjct: 815 ASAQPTDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQ 874
Query: 211 APVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPAASPESRKS 270
A S +S+ + P + F P + +SP+ P WGP E +
Sbjct: 875 AEASSDSIFHSQGTP-----NSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTEL 929
Query: 271 ART---TSPEPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNP 327
+R T PEP ++P W+ V+P + G P P+ + S P
Sbjct: 930 SRRHNWTKPEP------QAPVAWE--------------RVAPSNLPQGHP-LPKSFSSPP 968
Query: 328 SASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPPASP 387
S S+ K + + P P S P P P++ + SS +++ P
Sbjct: 969 SPSN---KREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLG-RQSSPPRNNYSDLRQLP 1024
Query: 388 ESWKSGPPEL 397
+ PP L
Sbjct: 1025 NAGPGAPPAL 1034
Score = 37.7 bits (86), Expect = 0.043
Identities = 74/341 (21%), Positives = 115/341 (33%), Gaps = 43/341 (12%)
Query: 118 PCNSAEPKSIPALSMETQKLGSVLSPESPKPTPLTPLEPQKP-GSVVSPELQTPLPSPEP 176
P + S P ++ ++ S + PT + L +K G PE P
Sbjct: 669 PATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTP 728
Query: 177 SKPASVSSPEPPKSVPVCESQKLAPVPSPEP----QKPAPVSPESVKATLSNPKPQKQSH 232
S+ SP +P ++ A P + P P +++LS ++ +
Sbjct: 729 SQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLS----REVAV 784
Query: 233 FPETLGPPSASSPESPVLAASPEPWGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKP 292
TL A+ P PV P P A P + SA+ T R P E E P
Sbjct: 785 VMPTLARGGAAGPGEPVEVKEP----PGLPAKPPA--SAQPTDELLRHPVTGEVVERGSP 838
Query: 293 FPAVSPEPRRPAPAVSPGS--WKPGPPGSPRPWKSNPSASSGPWKPAKPAPS---VSPGP 347
+ +R S G+ + PGS R ASS ++ P+ V P
Sbjct: 839 MALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKL 898
Query: 348 WK------PIPSVSPGPWKP--------TPSVSSASW-KSSSVSPSSWKSPPAS------ 386
K P+ + P W P T +W K +P +W+ S
Sbjct: 899 PKEAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGH 958
Query: 387 --PESWKSGPPELRKTAPTLSPEHWKAVPPVSPELRKPGPP 425
P+S+ S P K +++ +PP P PP
Sbjct: 959 PLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPP 999
>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo
sapiens]
Length = 1188
Score = 86.7 bits (213), Expect = 8e-17
Identities = 125/458 (27%), Positives = 164/458 (35%), Gaps = 86/458 (18%)
Query: 170 PLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSP---EPQKPAPVS--PESVKATLSN 224
P P P P P +S EPP P+ AP P P EP P ++ P V LS
Sbjct: 142 PPPGPAPGPPQDIS--EPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSP 199
Query: 225 PKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPAASPESRKSARTTSPEPRKPSPS 284
P P PP P P+ +P P P PA +P + S T + P
Sbjct: 200 PHTLSSPSIPT---PPDFIPPAPPLAFLAPPP-PPVPAPAPPAPASPHTVG---TRLFPP 252
Query: 285 ESPEPWKPFPAVS---PEPRRPAPAVSPGSWKPGPPGS--------PRPWKSNP----SA 329
WK A++ E R +P SP K G PR +K P
Sbjct: 253 GGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRT 312
Query: 330 SSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPPASPES 389
SS P + A+ AP G K PS P P S + P+S P +PE
Sbjct: 313 SSIPVQEAQEAPRKEEGATKKAPSRLPLP------------PSFHIRPASQVYPDRAPE- 359
Query: 390 WKSGPPELRKTAPTLSP---------EHWKAVPPVSPELRKPGPPLSPEIRSPAGSPELR 440
P EL+ TAP SP + PP +P L P PPL P P
Sbjct: 360 -PDCPGELKATAPA-SPRLGQSQSQADERAGTPPPAPPLPPPAPPLPP--------PAPP 409
Query: 441 KPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGSPDLWKSSFFIEPQKPVFPETRKPG 500
P +P L P +K + F ++ KSS SP L +P P T
Sbjct: 410 LPPAAPPL----PCAQKAAHPPAGFTKTPKSS---SPALKP-----KPNPPSPENTASSA 457
Query: 501 P---SGPSESPKAASDIWKPVLSIDTEPRKPALFPEPAKTAPPASPEARKRALFPE---- 553
P PS+ K +++ + E R L P T P S E +K PE
Sbjct: 458 PVDWRDPSQMEKLRNELAAYLCGSRREDR--FLSHRPGPTVAPQSKEGKKGPRLPEKETL 515
Query: 554 ---PRKHALFPELPKSALFSESQKAVELGDELQIDAID 588
P K P +P+ +L S E L + ++D
Sbjct: 516 LSLPAKDTP-PGVPEKSLGGSSLTETEAAPSLTLPSVD 552
Score = 85.9 bits (211), Expect = 1e-16
Identities = 151/636 (23%), Positives = 220/636 (34%), Gaps = 121/636 (19%)
Query: 103 TDPVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKPTPLTPLEPQKPGSV 162
++P PLP P ++A P P L +E S+ P P L+P P ++
Sbjct: 155 SEPPGGSPLPS----PPSTAPPP--PPLLLEPPPPPSMAPPPPPVLEALSP-----PHTL 203
Query: 163 VSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQKPAPVSPESVKATL 222
SP + TP P+ P + +P PP PVP+P P PAP SP +V L
Sbjct: 204 SSPSIPTPPDFIPPAPPLAFLAPPPP------------PVPAPAP--PAPASPHTVGTRL 249
Query: 223 SNP-----------KPQKQSHFPETLGPPSASSPESPVLAASPEPW--------GPSPAA 263
P +Q+ P S + P+ L +PEP P P
Sbjct: 250 FPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTP 309
Query: 264 SPESRKSARTTSPEPRK--------PSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPG 315
S + PRK PS P + PA P R PG K
Sbjct: 310 VRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKAT 369
Query: 316 PPGSPRPWKSNPSAS--SGPWKPAKPAPSVS---PGPWKPIPSVS------------PGP 358
P SPR +S A +G PA P P + P P P+P + P
Sbjct: 370 APASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAG 429
Query: 359 WKPTPSVSSASWKSSSVSPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPE 418
+ TP SS + K PS + ++P W+ P ++ K L+ +
Sbjct: 430 FTKTPKSSSPALKPKPNPPSPENTASSAPVDWRD-PSQMEKLRNELAAYLCGSRREDRFL 488
Query: 419 LRKPGPPLSPEIRSPAGSPELRKPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGS-- 476
+PGP ++P+ + P L P+ L K +P P + S GGS
Sbjct: 489 SHRPGPTVAPQSKEGKKGPRL------PEKETLLSLPAKDTP-----PGVPEKSLGGSSL 537
Query: 477 ------PDLWKSSFFIEPQKPVFPETRKPGPSGPSESPKAASDIWKPVLSIDTEPRKPAL 530
P L S PQ P R+ + AA KP SI + P KP L
Sbjct: 538 TETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKP--SIGSLPPKPRL 595
Query: 531 ----------------------FPEPAKTAPPASPEARKRALFPE-PRKHALFPEL-PKS 566
P + T P + K L P P K P + PK+
Sbjct: 596 EGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKA 655
Query: 567 ALFSESQKAVELGDELQIDAIDDQKCDI-LVQEELLASPKKLLEDTLFPSSKKLKKDNQE 625
L+ + LG + A + +AS L T S +KD+
Sbjct: 656 TLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTT--TSQLMAEKDSGP 713
Query: 626 SSDAELSSSEYIKTDLDAMDIKGQESSSDQEQVDVE 661
+ E +S+ + T A +G+ S S+ ++ +
Sbjct: 714 AGQPEKPASQEVSTPSQA---RGEGSPSEATRLPTQ 746
Score = 40.0 bits (92), Expect = 0.009
Identities = 67/310 (21%), Positives = 106/310 (34%), Gaps = 47/310 (15%)
Query: 105 PVKSPP----LPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKPTPLTPLEPQKPG 160
P K+ P +P K C+ + A+ M T G P P P P KP
Sbjct: 755 PPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPP 814
Query: 161 SVVSPE---LQTPLP-------SPEPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQKP 210
+ P L+ P+ SP A+ + +SV + P +
Sbjct: 815 ASAQPTDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQ 874
Query: 211 APVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPAASPESRKS 270
A S +S+ + P + F P + +SP+ P WGP E +
Sbjct: 875 AEASSDSIFHSQGTP-----NSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTEL 929
Query: 271 ART---TSPEPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNP 327
+R T PEP ++P W+ V+P + G P P+ + S P
Sbjct: 930 SRRHNWTKPEP------QAPVAWE--------------RVAPSNLPQGHP-LPKSFSSPP 968
Query: 328 SASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPPASP 387
S S+ K + + P P S P P P++ + SS +++ P
Sbjct: 969 SPSN---KREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLG-RQSSPPRNNYSDLRQLP 1024
Query: 388 ESWKSGPPEL 397
+ PP L
Sbjct: 1025 NAGPGAPPAL 1034
Score = 37.7 bits (86), Expect = 0.043
Identities = 74/341 (21%), Positives = 115/341 (33%), Gaps = 43/341 (12%)
Query: 118 PCNSAEPKSIPALSMETQKLGSVLSPESPKPTPLTPLEPQKP-GSVVSPELQTPLPSPEP 176
P + S P ++ ++ S + PT + L +K G PE P
Sbjct: 669 PATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTP 728
Query: 177 SKPASVSSPEPPKSVPVCESQKLAPVPSPEP----QKPAPVSPESVKATLSNPKPQKQSH 232
S+ SP +P ++ A P + P P +++LS ++ +
Sbjct: 729 SQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLS----REVAV 784
Query: 233 FPETLGPPSASSPESPVLAASPEPWGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKP 292
TL A+ P PV P P A P + SA+ T R P E E P
Sbjct: 785 VMPTLARGGAAGPGEPVEVKEP----PGLPAKPPA--SAQPTDELLRHPVTGEVVERGSP 838
Query: 293 FPAVSPEPRRPAPAVSPGS--WKPGPPGSPRPWKSNPSASSGPWKPAKPAPS---VSPGP 347
+ +R S G+ + PGS R ASS ++ P+ V P
Sbjct: 839 MALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKL 898
Query: 348 WK------PIPSVSPGPWKP--------TPSVSSASW-KSSSVSPSSWKSPPAS------ 386
K P+ + P W P T +W K +P +W+ S
Sbjct: 899 PKEAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGH 958
Query: 387 --PESWKSGPPELRKTAPTLSPEHWKAVPPVSPELRKPGPP 425
P+S+ S P K +++ +PP P PP
Sbjct: 959 PLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPP 999
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 86.3 bits (212), Expect = 1e-16
Identities = 95/346 (27%), Positives = 113/346 (32%), Gaps = 40/346 (11%)
Query: 109 PPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKPTPLTPLEPQKPGSVVSPELQ 168
PPLP +P IP G+ + P P P PL P PG+ + P
Sbjct: 924 PPLPGAGILPLPPLPGAGIPP---PPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPP 980
Query: 169 TP---LPSPEPSKPASVSSPEPPKSVPVCESQKLA----PVPSPEPQKPAPVSPESVKAT 221
P +P P P A + P P + L P P P P P P A
Sbjct: 981 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1040
Query: 222 LSNPKPQKQSHFPETLGPPSASSPESPVLAAS---PEPWGPSPAASPESRKSARTTSPEP 278
+ P P + P P A P P L + P P P P P P
Sbjct: 1041 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1100
Query: 279 RKPSPSESPEPWKPFPAVSPEPRRPA-----PAVSPGSWKPGPPGSPRPWKSNPSASSGP 333
P P P P + P P P P PG+ P PP PR P G
Sbjct: 1101 PLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGA 1160
Query: 334 W-KPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPPASPESWKS 392
P P P P P+P V P P P V + P PP P +
Sbjct: 1161 GIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVG--------IPP-----PPPLPGAGIP 1207
Query: 393 GPPELR------KTAPTLSPEHWKAVPPVSPELRKPGPPLSPEIRS 432
PP L AP L P PP P L GPPL P++ S
Sbjct: 1208 PPPPLPGMGIPPAPAPPLPPPGTGIPPP--PLLPVSGPPLLPQVGS 1251
Score = 81.3 bits (199), Expect = 3e-15
Identities = 143/646 (22%), Positives = 207/646 (32%), Gaps = 96/646 (14%)
Query: 94 KPKNQLNKETDPVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKPTP--- 150
+P + ++ E + K CN P +P + G + P P P P
Sbjct: 828 QPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMT 887
Query: 151 -------LTPLEPQKPGSVVSPELQTPLPS----PEPSKPASVSSPEPP---KSVPVCES 196
P P G+ + P PLP P P P + P PP +P
Sbjct: 888 VPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPP 947
Query: 197 QKLAPVPSPEPQKPA--PVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAAS- 253
A +P P P A P+ P A + P P + P P A P P L +
Sbjct: 948 LPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1007
Query: 254 --PEPWGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGS 311
P P P P P P P P P P + P P P + P
Sbjct: 1008 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1067
Query: 312 WKPG---PPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSA 368
PG PP P P P P P P P P+P V P P P
Sbjct: 1068 PLPGAGIPPPPPLPGAGIP--------PPPPLPGAGIPPPPPLPGVGIPPPPPLP----- 1114
Query: 369 SWKSSSVSPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPELRKPGPPLSP 428
+ + P PP P + PP L P PP P + P PP P
Sbjct: 1115 ---GAGIPP-----PPPLPGAGIPPPPPL--------PGAGIPPPPPLPRVGIPPPPPLP 1158
Query: 429 EIRSPAGSPELRKPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGSPDLWKSSFFIEP 488
P P +G P L + P G P P
Sbjct: 1159 GAGIPPPPP--LPGAGIPPPPPL---------PGVGIPPPPPLPGVGIPPPPPLPGAGIP 1207
Query: 489 QKPVFPETRKPGPSGPSESPKAASDIWKPVLSIDTEPRKPAL------FPEPAKTAPPAS 542
P P P P P P+L + P P + P+ PP
Sbjct: 1208 PPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPL 1267
Query: 543 PE------------ARKRALFP-EPRKHALFPELPKSALFSESQKAVEL-GDELQIDAID 588
P +RK+ + P P K + + L S+ + L ++++ +ID
Sbjct: 1268 PSGLFGLGMNQDKGSRKQPIEPCRPMKPLYWTRI---QLHSKRDSSTSLIWEKIEEPSID 1324
Query: 589 DQKCDILVQEELLASPKKLLEDTLFPSSK----KLKKDNQESSDAELSSSEYIKTDLDAM 644
+ + L + + KK + DT+ + KL + + + L SS + LD
Sbjct: 1325 CHEFEELFSKTAVKERKKPISDTISKTKAKQVVKLLSNKRSQAVGILMSSLH----LDMK 1380
Query: 645 DIKGQESSSDQEQVDVESIDFSKENKMDMTSPEQSRNVLQFTEEKE 690
DI+ + D VD+E++ EN+ E+ + +++KE
Sbjct: 1381 DIQHAVVNLDNSVVDLETLQALYENRAQSDELEKIEKHGRSSKDKE 1426
Score = 43.9 bits (102), Expect = 6e-04
Identities = 59/204 (28%), Positives = 85/204 (41%), Gaps = 37/204 (18%)
Query: 131 SMETQKLGSVLS--PESPKPTPLTPLEPQKPGSVVSPELQTPLPSPEPS---KPASVSSP 185
S +T++ S LS PES P P +P PG + E + LP+ +P+ P+S + P
Sbjct: 266 SPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPS-LPAAQPAAKDSPSSTAFP 324
Query: 186 -------EPPKSVPV---------CESQKLAPVPSPEP-QKPAPVSPESVKATLSNPKPQ 228
E PV E P P ++ AP E L +P+
Sbjct: 325 FPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGE-EPE 383
Query: 229 KQSHFPETLGPPSASSPESPVLAASPEPWGPSPAASPESRKSARTTSPEPRKPSPSESPE 288
+++ P+ P +AS P SP A S + P P +P K+ P SPS+SP
Sbjct: 384 EEAQGPD--APAAASLPGSP--APSQRCFKPYPLITPCYIKTTTRQLSSPNH-SPSQSPN 438
Query: 289 PWKPFPAVSPE-PRRPAPAVSPGS 311
SP RRP P++S GS
Sbjct: 439 Q-------SPRIKRRPEPSLSRGS 455
Score = 42.0 bits (97), Expect = 0.002
Identities = 52/218 (23%), Positives = 80/218 (36%), Gaps = 15/218 (6%)
Query: 156 PQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQKPAPVSP 215
P P + + + LP ++P P P +PV E+ L P Q A SP
Sbjct: 264 PGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSL-----PAAQPAAKDSP 318
Query: 216 ESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPAASPESRKSARTTS 275
S P + E G P + ++ + + +P SP +
Sbjct: 319 SSTAFPFPEAGPGE-----EAAGAPVRGAGDTDE-EGEEDAFEDAPRGSPGEEWAPEVGE 372
Query: 276 PEPRKPSPSESPEPWKP-FPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPW 334
P++ E P PA + P PAP S +KP P +P K+ S P
Sbjct: 373 DAPQRLGEEPEEEAQGPDAPAAASLPGSPAP--SQRCFKPYPLITPCYIKTTTRQLSSPN 430
Query: 335 KPAKPAPSVSPG-PWKPIPSVSPGPWKPTPSVSSASWK 371
+P+ SP +P PS+S G SV++ + K
Sbjct: 431 HSPSQSPNQSPRIKRRPEPSLSRGSRTALASVAAPAKK 468
Score = 39.7 bits (91), Expect = 0.011
Identities = 66/272 (24%), Positives = 103/272 (37%), Gaps = 64/272 (23%)
Query: 242 ASSPESPVLAASPEPW----------GPSPAA-----SPESRK--SARTTSPEPRKPSPS 284
A P +P A SP+P GPS A SP++ + SA + PE P
Sbjct: 229 AEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPR 288
Query: 285 ESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVS 344
E +P P+P P S P P + K +PS+++ P+ A P +
Sbjct: 289 EPQQP-------------PSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAA 335
Query: 345 PGP---------------WKPIPSVSPG-PWKPTPSVSSASWKSSSVSPSSWKSPPASPE 388
P ++ P SPG W P V + + P P +P
Sbjct: 336 GAPVRGAGDTDEEGEEDAFEDAPRGSPGEEW--APEVGEDAPQRLGEEPEEEAQGPDAPA 393
Query: 389 SWKSGPPELRKTAPTLSPEHWKAVPPVSPELRKPGPPLSPEIRSPAGSPELRKPSGSPDL 448
+ S P +P S +K P ++P K + ++ SP SP + P+ SP +
Sbjct: 394 A-ASLP-----GSPAPSQRCFKPYPLITPCYIK---TTTRQLSSPNHSPS-QSPNQSPRI 443
Query: 449 WKLSPDQ-----RKTSPASLDFPESQKSSRGG 475
K P+ +T+ AS+ P + + GG
Sbjct: 444 -KRRPEPSLSRGSRTALASVAAPAKKHRADGG 474
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 85.1 bits (209), Expect = 2e-16
Identities = 111/455 (24%), Positives = 157/455 (34%), Gaps = 61/455 (13%)
Query: 143 PESPKPTPLTPLEPQKPGSVVSPELQTPLPS-PEPSKPASVSSPEP--PKSVPVCESQKL 199
P+ P P P P P P P P PS P+ + PA SSP P VPV E Q
Sbjct: 754 PQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLP 813
Query: 200 APVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSP---ESPVLAASPEP 256
V P P+ L P+P+ H P+ PP S+P + + P
Sbjct: 814 GSVFDPIGHFTQPI--------LHLPQPELPPHLPQ---PPEHSTPPHLNQHAVVSPPAL 862
Query: 257 WGPSPAASPESRKSARTTSPEPRKP---SPSESPEPWKPFPAVSPEPR-------RPAPA 306
P A P+P +P SP+ + P P P ++ P+ PAP
Sbjct: 863 HNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPP 922
Query: 307 VS---------------------PGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSP 345
++ P P P P +PS + P P P
Sbjct: 923 LTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQP 982
Query: 346 GPWKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPPASPESWKSGPPELRKTAPTL- 404
P P P P S P + PP P + PP+ K +
Sbjct: 983 QP-PPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQ 1041
Query: 405 ---SPEHWKAVPPVSPELRKPGPPLSPEIRSPAGSPELRKPSGSPDLWKLSPDQRKTSPA 461
SP H K+ P + LR+ PL I SP S SP + P +++ A
Sbjct: 1042 HHHSPRHHKSDPYSTGHLREAPSPLM--IHSPQMSQFQSLTHQSPPQQNVQPKKQELRAA 1099
Query: 462 SLDFPES---QKSSRGGSPDLWKSSF--FIEPQKPVFPETRKPGPSGPSESPKAASDIWK 516
S+ P+ K + SP + F + P+ P PE+ K P D+ +
Sbjct: 1100 SVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGR 1159
Query: 517 PVLSIDTEPRKPALFPEPAK-TAPPASPEARKRAL 550
PV+ + P P+ K P +P A K+ L
Sbjct: 1160 PVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDL 1194
Score = 77.8 bits (190), Expect = 4e-14
Identities = 122/485 (25%), Positives = 180/485 (37%), Gaps = 109/485 (22%)
Query: 109 PPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKP---TPLTPLEPQKPGSVVSP 165
PP P+ Q+ P P S+P + K SP P T + LEPQ PGSV P
Sbjct: 767 PPPPQQQQQPPPPPPPPSMPQQAAPAMK-------SSPPPFIATQVPVLEPQLPGSVFDP 819
Query: 166 --------------ELQTPLPSP--------------------------EPSKPASVSSP 185
EL LP P +PS+P++ ++
Sbjct: 820 IGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAA 879
Query: 186 EPPKSV-PVCESQKLAPVPSPEPQKPAPVSPESVKATLSNPKP-----QKQSHFPET--L 237
PPK P S L P PQ P P+ + P P Q Q + + +
Sbjct: 880 LPPKPARPPAVSPALTQTPLL-PQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKV 938
Query: 238 GPPSASSPESPVLAASPEPWGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVS 297
PP+ P V + P P P P S + + + P P +P P + P V
Sbjct: 939 QPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVH 998
Query: 298 PEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSV----SPGPWKPIPS 353
+P + + + +P PP +P P P +PAKP + SP K P
Sbjct: 999 LQPMQFSTHIQ----QPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDP- 1053
Query: 354 VSPGPWKPTPS-VSSASWKSSSVSPSSWKSPP---ASPESWKSGPPELRKTAPTLSPEHW 409
S G + PS + S + S + +SPP P+ + + + P + +
Sbjct: 1054 YSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEE 1113
Query: 410 KAVPPV------SPELRKPGPPLSPE-IRSPAGSPELRKPSGSP-DLWKLSPDQRKTSPA 461
K P+ SP LR P PP PE I++P P+ +P P D+ + P R
Sbjct: 1114 KIHSPIIRSEPFSPSLR-PEPPKHPESIKAPVHLPQ--RPEMKPVDVGR--PVIR----- 1163
Query: 462 SLDFPESQKSSRGGSPDLWKSSFFIEPQKPVFPETR-------------KPGPSGPSESP 508
P Q + G+PD K EP+ PV P+ + P+ PS +
Sbjct: 1164 ----PPEQNAPPPGAPD--KDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTA 1217
Query: 509 KAASD 513
K++SD
Sbjct: 1218 KSSSD 1222
Score = 45.8 bits (107), Expect = 2e-04
Identities = 48/177 (27%), Positives = 69/177 (38%), Gaps = 31/177 (17%)
Query: 156 PQKPGSVVSPELQTPLPSPEPSKPASVSSPEP-PKSVP--VCESQKLAPVPSPEPQKPAP 212
P + P+ QTP P+P P + ++P P P P + ++ + VP Q P P
Sbjct: 197 PNTTQASTPPQTQTPQPNPPPVQ----ATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPP 252
Query: 213 VSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPAASPESRKSAR 272
V P+ P+P QSH P++AA+P+P ++ A
Sbjct: 253 VPPQPQPPPAPAPQPV-QSH--------------PPIIAATPQPVKTKKGV----KRKAD 293
Query: 273 TTSP---EPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSN 326
TT+P +P PS PEP E RP P P P P KS+
Sbjct: 294 TTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVK--PPKKDVPDSQQHPAPEKSS 348
Score = 44.7 bits (104), Expect = 4e-04
Identities = 99/491 (20%), Positives = 156/491 (31%), Gaps = 54/491 (10%)
Query: 90 KWNDKPKNQLNKETDPVKSPPLPEHQKIPCNSAEPKSIPA---LSMETQKLGS------- 139
K N N KE P+KS P P ++ + +P S LS++ KL
Sbjct: 575 KNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVV 634
Query: 140 -VLSPESPKPTPLTPLEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQK 198
++ P P E + + P L S P+ K + S K
Sbjct: 635 HIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSK 694
Query: 199 LAPVPSPEPQKPAPVSPESVK--ATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEP 256
+ S E + + S + T PK +K+ H P +
Sbjct: 695 MKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGH-------PGREQKKHHHHHHQQMQ 747
Query: 257 WGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGP 316
P+P P+ P P + P P P P P P P++ P P
Sbjct: 748 QAPAPV-------------PQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSM-PQQAAPAM 793
Query: 317 PGSPRPWKSNPSASSGPWKPAKPAPSVS--PGPWKPIPSVSPGPWKPTPSVSSASWKSSS 374
SP P+ + P P + P +P P P P S
Sbjct: 794 KSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHST---PPH 850
Query: 375 VSPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPELRK----PGPPLS--P 428
++ + SPPA + P A L P+ + P VSP L + P PP++ P
Sbjct: 851 LNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARP-PAVSPALTQTPLLPQPPMAQPP 909
Query: 429 EIRSPAGSPELRKPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGSPDLWKSSFFIEP 488
++ P P S + +K P + P + S+ P ++
Sbjct: 910 QVLLEDEEPP-APPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQ 968
Query: 489 QKPVFPETRKPGPSGPSESPKAASDIWKPVLSIDTEPRKPALF---PEPAKTAPPASPEA 545
Q + + P P P P P + +P + + P P + P P
Sbjct: 969 QL----QQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPP 1024
Query: 546 RKRALFPEPRK 556
++ P+P K
Sbjct: 1025 GQQPPPPQPAK 1035
Score = 41.6 bits (96), Expect = 0.003
Identities = 47/176 (26%), Positives = 71/176 (40%), Gaps = 26/176 (14%)
Query: 272 RTTSPEPRKPSPSESPEPWKPFPAVSPE--PRRPAPAVSPGSWKPGPPGSPRPWKSNPSA 329
+T +P+P P +P P FPAV+P+ + P V P P+P ++ P
Sbjct: 207 QTQTPQPNPPPVQATPHP---FPAVTPDLIVQTPVMTVVP----------PQPLQTPPPV 253
Query: 330 SSGPWKPAKPAPS-VSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPPASPE 388
P P PAP V P PI + +P P K V + ++ + PP
Sbjct: 254 PPQPQPPPAPAPQPVQSHP--PIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPP---- 307
Query: 389 SWKSGPPELRKTAPTLSPEHWKAVPPVSPELRKPGPPLSPEIRSPAGSPELRKPSG 444
S PPE + T E + V P ++ +PE +S S +L+ SG
Sbjct: 308 ---SLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPE-KSSKVSEQLKCCSG 359
Score = 41.2 bits (95), Expect = 0.004
Identities = 46/193 (23%), Positives = 70/193 (36%), Gaps = 25/193 (12%)
Query: 94 KPKNQLNKETDPVK----SPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKPT 149
K + + KET K + P P + P+ P T ++P+ T
Sbjct: 177 KGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQT 236
Query: 150 PLTPLEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQK 209
P+ + P +P LQTP P P +P +P+P +S P P+ + PQ
Sbjct: 237 PVMTVVPPQP-------LQTPPPVPPQPQPPPAPAPQPVQSHP--------PIIAATPQP 281
Query: 210 PAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPAASPESRK 269
KA + P H P +L PP + + S P P P+S++
Sbjct: 282 VKTKKGVKRKADTTTPTTIDPIHEPPSL-PPEPKTTKLGQRRESSRPVKPPKKDVPDSQQ 340
Query: 270 SARTTSPEPRKPS 282
P P K S
Sbjct: 341 -----HPAPEKSS 348
Score = 37.7 bits (86), Expect = 0.043
Identities = 37/155 (23%), Positives = 54/155 (34%), Gaps = 29/155 (18%)
Query: 85 HASPDKWNDKPKNQLNKETDPVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPE 144
H SP + N +PK Q + V+ PL + ++ +K+ S +
Sbjct: 1081 HQSPPQQNVQPKKQELRAASVVQPQPL------------------VVVKEEKIHSPIIRS 1122
Query: 145 SPKPTPLTPLEPQKPGSVVSPELQTPLPSPEPSKPASVSSP--------EPPKSVPVCES 196
P L P P+ P S+ +P LP KP V P PP P +
Sbjct: 1123 EPFSPSLRPEPPKHPESIKAP---VHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDK 1179
Query: 197 QKLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQS 231
QK P P+K + A+L P S
Sbjct: 1180 QKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPS 1214
Score = 35.0 bits (79), Expect = 0.28
Identities = 95/447 (21%), Positives = 159/447 (35%), Gaps = 80/447 (17%)
Query: 263 ASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRP 322
A R T + +P + + + P +P+P P +P P P +P
Sbjct: 176 AKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATP---HPFPAVTPDL 232
Query: 323 WKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKS 382
P + P +P + P V P P +P P+ +P P + P + +A+
Sbjct: 233 IVQTPVMTVVPPQPLQTPPPVPPQP-QPPPAPAPQPVQSHPPIIAAT------------- 278
Query: 383 PPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPELRKPGPPLSPEIRSPAGSPELRKP 442
P K G +++ A T +P + P P P P+ E +P
Sbjct: 279 --PQPVKTKKG---VKRKADTTTP------TTIDPIHEPPSLPPEPKTTKLGQRRESSRP 327
Query: 443 SGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGSPDLWKSSFFIEPQKPVFPETRKPGPS 502
P +K P S P +KSS+
Sbjct: 328 VKPP---------KKDVPDSQQHPAPEKSSK----------------------------- 349
Query: 503 GPSESPKAASDIWKPVLSIDTEPRKPALFPEPAKTAPPASPEARKRALFPEPRKHALFPE 562
SE K S I K + + +K A + P P EA + + KH +
Sbjct: 350 -VSEQLKCCSGILKEMFA-----KKHAAYAWP--FYKPVDVEALGLHDYCDIIKHPMDMS 401
Query: 563 LPKSALFS-ESQKAVELGDELQIDAIDDQKCDILVQEELLASPKKLLEDTLFPSSKKLKK 621
KS L + E + A E G ++++ + K + E++A +K L+D K+
Sbjct: 402 TIKSKLEAREYRDAQEFGADVRLMFSNCYKYN-PPDHEVVAMARK-LQDVFEMRFAKMPD 459
Query: 622 DNQESSDAELSSSEYIKTDLDAMDIKGQESSSDQEQVDVESIDFSKENKMDMTSPEQSRN 681
+ +E A S + T + A +SSSD S D S+E + + Q +
Sbjct: 460 EPEEPVVAVSSPAVPPPTKVVAPP-SSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQ- 517
Query: 682 VLQFTEEKEAFISEEEIAKYMKRGKGK 708
L+ E+ A +S+ + K K+ K K
Sbjct: 518 -LKAVHEQLAALSQPQQNKPKKKEKDK 543
>gi|112421108 capicua homolog [Homo sapiens]
Length = 1608
Score = 85.1 bits (209), Expect = 2e-16
Identities = 157/664 (23%), Positives = 243/664 (36%), Gaps = 154/664 (23%)
Query: 105 PVKSPPLPEHQKIPC-NSAEPKS--IPALSMETQKLGSVLSPESPKPTPLTPLEPQK--- 158
P+ SPP +P N A+P S I + ++ P SP P +PQK
Sbjct: 943 PLVSPPF----SVPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVLL 998
Query: 159 PGSVVSPELQTP----LP---SPEPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQKPA 211
P S +Q+ LP SP S+ +V+S P SV + S P PA
Sbjct: 999 PSSTRITYVQSAGGHALPLGTSPASSQAGTVTSYGPTSSVAL-------GFTSLGPSGPA 1051
Query: 212 PVSP--ESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAA----SPEPWGPSPAASP 265
V P + +A L P S P PP+ ++P PV+ A SP P +P A P
Sbjct: 1052 FVQPLLSAGQAPLLAPGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQP 1111
Query: 266 ESRKS------ARTTSPEPRK------PSPSES-PEPWKPFPA----------VSPEPRR 302
A +T+P P+P+ + P P PFP+ V+P+ +R
Sbjct: 1112 SQAPPSLVYTVATSTTPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQR 1171
Query: 303 PAP-----------AVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPI 351
P+P ++ GS++ G G P P P +P P + P P
Sbjct: 1172 PSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPPA 1231
Query: 352 PSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKA 411
P P W PT +SS P PPA + GP + P+ S + W+
Sbjct: 1232 PPPLPETWTPTA-------RSSPPLP-----PPAEERTSAKGPETMASKFPSSSSD-WR- 1277
Query: 412 VPPVSPELRKPGPPLSPEIRSPAGSPELRKPSGSPDLWKLSPDQRKTSPASLDFPESQKS 471
VP E R PP P SPA +P + P GS + + A+ D PE +++
Sbjct: 1278 VPGQGLENRGE-PPTPP---SPAPAPAV-APGGS--------SESSSGRAAGDTPERKEA 1324
Query: 472 SRGGSPDLWKSSFFIEPQKPVFPETRKPGPSGPSESPKAASDIWKPVLS-IDTEPRKPAL 530
+ G K P K + VLS +D E R L
Sbjct: 1325 AGTG----------------------KKVKVRPPPLKKTFDSVDNRVLSEVDFEERFAEL 1362
Query: 531 FPEPAKTAPPASPEARKRALFPEPRKHALFPELPKSALFSESQKAVELGDELQIDAIDDQ 590
PE R + P P +L P++ L S +K D +D+ +
Sbjct: 1363 ------------PEFRPEEVLPSPTLQSLATS-PRAILGSYRKKRKNSTD---LDSAPED 1406
Query: 591 KCDILVQEELLASPKKLLEDTLFPSSKKLKKDNQESSDAELSSSEYIKTDLDAMDIKGQE 650
SPK +K+++ + SS+ S + D+ D G E
Sbjct: 1407 P----------TSPK-----------RKMRRRSSCSSEPNTPKSAKCEGDIFTFDRTGTE 1445
Query: 651 SSSDQEQVDVESIDFSKENKMDMTSPEQSRNVLQFTEEKEAFISEEEIAKYMKRGKGKYY 710
+ +++ + + +S + T ++ V+Q ++ F S + A + R +
Sbjct: 1446 AEDVLGELEYDKVPYS---SLRRTLDQRRALVMQLFQDHGFFPSAQATAAFQARYADIFP 1502
Query: 711 CKIC 714
K+C
Sbjct: 1503 SKVC 1506
Score = 48.5 bits (114), Expect = 2e-05
Identities = 60/207 (28%), Positives = 82/207 (39%), Gaps = 30/207 (14%)
Query: 261 PAASPESRKSART--TSPEPRK----PSPSESP--EPWKPFPAVSP-EPRRPAPAVSPGS 311
PA+S SR T+ EPR P S P P +P P+V P E ++PA +
Sbjct: 10 PASSAASRGLGMFVWTNVEPRSVAVFPWHSLVPFLAPSQPDPSVQPSEAQQPASHPVASN 69
Query: 312 WKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWK 371
P S P +G P +P + P S PGP P V S
Sbjct: 70 QSKEPAESAAVAHERPPGGTGSADPERPPGATCP------ESPGPGPPHPLGVVESG--- 120
Query: 372 SSSVSPSSWKSPPASPESWKSGPP-ELRKTAPTLSPEHWKAVPPVSPELRKPGPPLSPEI 430
K PP + E SGPP E R + T S + +SPE++ P PP
Sbjct: 121 ---------KGPPPTTEEEASGPPGEPRLDSETESDHDDAFLSIMSPEIQLPLPPGKRRT 171
Query: 431 RSPAGSPELRKPSGSPDLWKLSPDQRK 457
+S + P+ R S D SP++R+
Sbjct: 172 QSLSALPKERDSSSEKD--GRSPNKRE 196
Score = 46.6 bits (109), Expect = 9e-05
Identities = 112/475 (23%), Positives = 154/475 (32%), Gaps = 53/475 (11%)
Query: 95 PKNQLNKETDPVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKPTPLTPL 154
P N+ +E + P P A P S PA +M T +V+ P S P P+
Sbjct: 634 PPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVT----NVVRPVSSTPVPIASK 689
Query: 155 EPQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQK---PA 211
G + T E + V P V +K A SP P P
Sbjct: 690 PFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAATSPAPHLVAGPL 749
Query: 212 PVSPESVKATLSN----------PKPQKQSHFPETL---------GPPSASSPESPVLAA 252
+ AT++N P P + G + S P PV
Sbjct: 750 LGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPGGGTTAGSGAGAGSGPNGPVPLG 809
Query: 253 SPEPWGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSW 312
+P A + T P+ + +P+ +P P A P PAP S
Sbjct: 810 ILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAPGTKAAA----PSGPAPTTSIRFT 865
Query: 313 KPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKS 372
PPG+ K + + P P SV P SVSP P P S+
Sbjct: 866 L--PPGTSTNGKVLAATAPTPGIPI--LQSVPSAPPPKAQSVSP-VQAPPPGGSAQLLPG 920
Query: 373 SSVSPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPELRKPGPPLSPEIRS 432
+ P + +P S +G P + P P A PP P P +P
Sbjct: 921 KVLVPLA--APSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLV 978
Query: 433 PAGSP-ELRKPSGSPDLWKLSPDQRKTSPAS-----LDFPESQKSSRGGSPDLWKSSFFI 486
P SP L P+ P L R T S L S SS+ G+ +
Sbjct: 979 PPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQAGTVTSY------ 1032
Query: 487 EPQKPVFPETRKPGPSGPSESPKAASDIWKPVLSIDTEPRKPALFPEPAKTAPPA 541
P V GPSGP+ S P+L+ P + + P P+ PPA
Sbjct: 1033 GPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLA----PGQVGVSPVPSPQLPPA 1083
Score = 43.5 bits (101), Expect = 8e-04
Identities = 47/195 (24%), Positives = 73/195 (37%), Gaps = 23/195 (11%)
Query: 121 SAEPKSIPALSMETQKLGSVLSPESPKPTPLTPLEPQKPGSVVSPELQTPLPSPEPSKPA 180
+ EP+S+ + L L+P P P+ + P E Q+P S Q S EP++ A
Sbjct: 26 NVEPRSVAVFPWHS--LVPFLAPSQPDPS-VQPSEAQQPASHPVASNQ----SKEPAESA 78
Query: 181 SVSSPEPPKSVPVCESQKLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPP 240
+V+ PP + ++ PE P P P V + P P + E GPP
Sbjct: 79 AVAHERPPGGTGSADPERPPGATCPESPGPGPPHPLGVVESGKGPPPTTEE---EASGPP 135
Query: 241 SASSPESP---------VLAASPEPWGPSPAASPESRKSARTTSPEPRKPSPSESPEPWK 291
+S + SPE P P ++ ++ S P++ S +
Sbjct: 136 GEPRLDSETESDHDDAFLSIMSPEIQLP----LPPGKRRTQSLSALPKERDSSSEKDGRS 191
Query: 292 PFPAVSPEPRRPAPA 306
P RRP A
Sbjct: 192 PNKREKDHIRRPMNA 206
Score = 42.4 bits (98), Expect = 0.002
Identities = 49/188 (26%), Positives = 69/188 (36%), Gaps = 28/188 (14%)
Query: 121 SAEPKSIPALSMETQKLGSVLSPESPKPTPLTPLEPQKPGSVVSPELQTPLPSPEPSKPA 180
SA +PA S ++ LG + T +EP+ L L +P
Sbjct: 3 SAHRPLMPASSAASRGLGMFV---------WTNVEPRSVAVFPWHSLVPFLAPSQPDPSV 53
Query: 181 SVSSPEPPKSVPVCESQKLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPP 240
S + P S PV +Q S EP + A V+ E + P++ PP
Sbjct: 54 QPSEAQQPASHPVASNQ------SKEPAESAAVAHERPPGGTGSADPER---------PP 98
Query: 241 SASSPESPVLAASPEPWG---PSPAASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVS 297
A+ PESP P P G P + + A EPR S +ES +S
Sbjct: 99 GATCPESPG-PGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETESDHDDAFLSIMS 157
Query: 298 PEPRRPAP 305
PE + P P
Sbjct: 158 PEIQLPLP 165
Score = 40.8 bits (94), Expect = 0.005
Identities = 32/91 (35%), Positives = 42/91 (46%), Gaps = 13/91 (14%)
Query: 282 SPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWK---PAK 338
+P+E P P P P P A A +P P P G P P ++PS+ SG + P
Sbjct: 1523 TPTEQP-PGAEAPLPVPPPTGTAAAPAP---TPSPAGGPDP--TSPSSDSGTAQAAPPLP 1576
Query: 339 PAPSVSPGP--WKPIPSVSPGPWKPTPSVSS 367
P P PG W+ P SP P P PS ++
Sbjct: 1577 PPPESGPGQPGWEGAPQPSPPP--PGPSTAA 1605
Score = 40.4 bits (93), Expect = 0.007
Identities = 27/87 (31%), Positives = 37/87 (42%), Gaps = 10/87 (11%)
Query: 135 QKLGSVLSPESPKPTPLTPLEPQKPGSVVSPELQTPLPS--PEPSKPASVSS-------- 184
QK+ +P P PL P + TP P+ P+P+ P+S S
Sbjct: 1516 QKIMQAATPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPL 1575
Query: 185 PEPPKSVPVCESQKLAPVPSPEPQKPA 211
P PP+S P + AP PSP P P+
Sbjct: 1576 PPPPESGPGQPGWEGAPQPSPPPPGPS 1602
Score = 38.9 bits (89), Expect = 0.019
Identities = 33/113 (29%), Positives = 44/113 (38%), Gaps = 33/113 (29%)
Query: 152 TPLEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQKPA 211
TP E Q PG+ + PLP P P+ A+ +P P +P P+P P
Sbjct: 1523 TPTE-QPPGA------EAPLPVPPPTGTAAAPAPTP------------SPAGGPDPTSP- 1562
Query: 212 PVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPAAS 264
S +S A + P P PP S P P +P+P P P S
Sbjct: 1563 --SSDSGTAQAAPPLP-----------PPPESGPGQPGWEGAPQPSPPPPGPS 1602
Score = 36.2 bits (82), Expect = 0.13
Identities = 59/245 (24%), Positives = 80/245 (32%), Gaps = 55/245 (22%)
Query: 153 PLEPQKPGSVVSPEL----QTPLPSPEPSKPASVSSPEPP---------KSVPVCESQKL 199
PL+P+ PG P PS S PAS S+ K+ +
Sbjct: 509 PLDPEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGSTA 568
Query: 200 APVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLG------------PPSASSPES 247
P+ P P P +P L + PE++G PPS
Sbjct: 569 GPLRPPPPGAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPGPSVIAAPPSGGGNIL 628
Query: 248 PVLAASPE-----------PWGPSPA------ASPESRKSARTTSPEPRKPSPSESPEPW 290
L P P P+P+ A+P SR +A + R S + P
Sbjct: 629 QTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVTNVVRPVSSTPVPIAS 688
Query: 291 KPFPA---VSPEPRRPAPA---VSPGSWKPG--PPGSPRPWKSNPSASSGPWKPAKPAPS 342
KPFP P A A + GS PG P G + SA++ PAP
Sbjct: 689 KPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAA-----TSPAPH 743
Query: 343 VSPGP 347
+ GP
Sbjct: 744 LVAGP 748
Score = 35.4 bits (80), Expect = 0.21
Identities = 32/96 (33%), Positives = 43/96 (44%), Gaps = 14/96 (14%)
Query: 262 AASP-ESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSP 320
AA+P E A P P + +P P P PA P+P +P+ G+ + PP P
Sbjct: 1521 AATPTEQPPGAEAPLPVPPPTGTAAAPAP-TPSPAGGPDP--TSPSSDSGTAQAAPPLPP 1577
Query: 321 RPWKSNPSASSGPWKPA-KPAPSVSPGPWKPIPSVS 355
P SGP +P + AP SP P P PS +
Sbjct: 1578 PP-------ESGPGQPGWEGAPQPSPPP--PGPSTA 1604
Score = 35.4 bits (80), Expect = 0.21
Identities = 23/89 (25%), Positives = 34/89 (38%), Gaps = 4/89 (4%)
Query: 220 ATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPAASPESRKSARTTSPEPR 279
AT + P ++ P PP + +P SP GP P + +A+ P P
Sbjct: 1522 ATPTEQPPGAEAPLPV---PPPTGTAAAPAPTPSPAG-GPDPTSPSSDSGTAQAAPPLPP 1577
Query: 280 KPSPSESPEPWKPFPAVSPEPRRPAPAVS 308
P W+ P SP P P+ A +
Sbjct: 1578 PPESGPGQPGWEGAPQPSPPPPGPSTAAT 1606
Score = 34.7 bits (78), Expect = 0.36
Identities = 53/229 (23%), Positives = 79/229 (34%), Gaps = 26/229 (11%)
Query: 95 PKNQLNKETDPVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKPT----- 149
P+++L + P PPLPE S+ P PA + K ++ + P +
Sbjct: 1219 PESELEGQPTPPAPPPLPETWTPTARSSPPLPPPAEERTSAKGPETMASKFPSSSSDWRV 1278
Query: 150 PLTPLEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQK 209
P LE + G +P P P+ P + SS P E ++ A K
Sbjct: 1279 PGQGLENR--GEPPTPPSPAPAPAVAPGGSSESSSGRAAGDTP--ERKEAAGT-----GK 1329
Query: 210 PAPVSPESVKATLSNPKPQKQSH--FPETLGPPSASSPESPVLAASPEPWGPSPAASPES 267
V P +K T + + S F E A PE P P S A SP +
Sbjct: 1330 KVKVRPPPLKKTFDSVDNRVLSEVDFEERF----AELPEFRPEEVLPSPTLQSLATSPRA 1385
Query: 268 ------RKSARTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPG 310
+K +T + P+ + + S EP P A G
Sbjct: 1386 ILGSYRKKRKNSTDLDSAPEDPTSPKRKMRRRSSCSSEPNTPKSAKCEG 1434
Score = 32.0 bits (71), Expect = 2.4
Identities = 61/289 (21%), Positives = 89/289 (30%), Gaps = 93/289 (32%)
Query: 160 GSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQKPAPVSPESVK 219
G+ +P + + L S S + P S C +++L V P +P S V
Sbjct: 304 GTAAAPGVSSELLSVAAQTLLSSDTKAPGSSS--CGAERLHTVGGPGSARPRAFSHSGVH 361
Query: 220 ----------------------ATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPW 257
A+ S PKP Q P GP +A + A P
Sbjct: 362 SLDGGEVDSQALQELTQMVSGPASYSGPKPSTQYGAP---GPFAAPGEGGALAATGRPPL 418
Query: 258 GPSPAASPESRKSARTTSPEPRK------------------------------------P 281
P+ A+ + S TS E R
Sbjct: 419 LPTRASRSQRAASEDMTSDEERMVICEEEGDDDVIADDGFGTTDIDLKCKERVTDSESGD 478
Query: 282 SPSESPEPWKPF-----------------PAVSPEPRRPAPAVSPGSWKPGPPGSPRPWK 324
S E PE K F P + PEP P P P ++ G +P
Sbjct: 479 SSGEDPEGNKGFGRKVFSPVIRSSFTHCRPPLDPEP--PGPPDPPVAFGKGYGSAPSSSA 536
Query: 325 SNPSASS-----------GPWKPAKPAPSVSPGPWKPIPSVSPGPWKPT 362
S+P++SS G +K + + GP +P P + GP P+
Sbjct: 537 SSPASSSASAATSFSLGSGTFKAQESGQGSTAGPLRPPPPGAGGPATPS 585
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 84.3 bits (207), Expect = 4e-16
Identities = 120/490 (24%), Positives = 179/490 (36%), Gaps = 58/490 (11%)
Query: 102 ETDPVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKPTPLTPLEPQK--- 158
+ P S PLP + P + +P P T + + +P+P+P P+K
Sbjct: 626 QAPPAVSTPLPLGLQQP-QAQQPPQAP-----TPQAAAPPQATTPQPSPGLASSPEKIVL 679
Query: 159 -------PGSVVSPE-LQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQKP 210
P ++++ + LQ LP +P S P V S AP P+ Q P
Sbjct: 680 GQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVS---APPPA---QDP 733
Query: 211 APVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPAASPESRKS 270
AP +P + A L P Q+ P+A+ + P ++SP +P S
Sbjct: 734 APATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPS 793
Query: 271 ARTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSAS 330
T P R PS +S P + P P AP PG + P SNP+
Sbjct: 794 PHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPA-- 851
Query: 331 SGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVS-------PSSWK-- 381
P P P P + P P + P P P S SSA SS S PS ++
Sbjct: 852 --PTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQ 909
Query: 382 -SPPASPESWKSGPPELR-----KTAPTLSPEHWKAVPPVSPELRKPGPPLSPEIRSPAG 435
P P + PP L P P ++ V P L +P L + P+G
Sbjct: 910 FPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSG 969
Query: 436 SPELRKPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGSPDLWKSSFFIEPQKPVFPE 495
K G+P + Q TS L P + G +P ++ P
Sbjct: 970 IILQNKAGGAP-----AAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAA 1024
Query: 496 TRKPGPSGPSESPKAASDIWKPVLSI----DTEPRKPALFPEPAKTA----PPASPEARK 547
T P P P+E+ AS++ P L++ + P KP+ +K + PP +++
Sbjct: 1025 TGLP-PLLPAENKAFASNL--PTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSKE 1081
Query: 548 RALFPEPRKH 557
KH
Sbjct: 1082 ACFLEHLHKH 1091
Score = 83.6 bits (205), Expect = 7e-16
Identities = 129/481 (26%), Positives = 176/481 (36%), Gaps = 106/481 (22%)
Query: 128 PALSMETQKLGSVLSPESPKPTPLTP---LEPQKPGSVVSPELQTPLPSPEPSKPASVSS 184
PA T L V P S TP ++P P + P P P +VS+
Sbjct: 574 PAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVST 633
Query: 185 PEPPKSVPVCESQKLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASS 244
P P + P+ Q+P Q+ P+ PP A++
Sbjct: 634 PLP------------LGLQQPQAQQP------------------PQAPTPQAAAPPQATT 663
Query: 245 PE-SPVLAASPEP--WGPSPAASPE---SRKSARTTSPEPRKPSPSESPEPW-------- 290
P+ SP LA+SPE G P+A+P ++ S + P+ R P + P
Sbjct: 664 PQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVI 723
Query: 291 --KPFPAVSPEPRRP-APAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAK-PAPSVSPG 346
P PA P P P A G P SP P P+A+ P K P PS SP
Sbjct: 724 VSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAA-----PLKGPGPSSSPS 778
Query: 347 PWKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPPASPESWKSGPPELRKTAPTLSP 406
P + P P+P + + S P S PP+ P PP+ T P +
Sbjct: 779 LPHQAP-LGDSPHLPSPHPTRPPSRPPS-RPQSVSRPPSEPPLHPCPPPQAPPTLPGIFV 836
Query: 407 -EHWKAVPP--VSPELRKPGPPLSPEIRSPAGSPELRKPSGS-PDLWKLSPDQRKTSPAS 462
++ VPP +P PGPP P +R P+ + P G P L P ++ AS
Sbjct: 837 IQNQLGVPPPASNPAPTAPGPP-QPPLR-----PQSQPPEGPLPPAPHLPPSSTSSAVAS 890
Query: 463 LDFPESQKSSRGGSPDLWKSSFFIEPQKPVFPETRKPGPSGPSESPKAASDIWKPVLSID 522
S+ SSR +P S F ++ FP ++ GP +SP
Sbjct: 891 ----SSETSSRLPAPT--PSDFQLQ-----FPPSQ-----GPHKSP-------------- 920
Query: 523 TEPRKPALFPEPAKTAPPASPEARKRALFPEPRKHALFPELPKSALFSESQKAVELGDEL 582
T P L PEPA PP P + P FP LP+ E V G L
Sbjct: 921 TPPPTLHLVPEPA-APPPPPPRTFQMVTTP-------FPALPQPKALLERFHQVPSGIIL 972
Query: 583 Q 583
Q
Sbjct: 973 Q 973
Score = 54.7 bits (130), Expect = 3e-07
Identities = 101/414 (24%), Positives = 148/414 (35%), Gaps = 78/414 (18%)
Query: 200 APVPSPEP---QKPAPVSPESVKATLSNPKPQKQSHFPETLG---PPSA----SSPESPV 249
AP+ +P Q P ++ S+ T S P P + G PPSA ++P+ V
Sbjct: 545 APIQVGQPALFQMPVSLAAGSLP-TQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLV 603
Query: 250 LAASPEPWGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSP 309
A+P AA+ T P P+ P P P P +P+ P +P
Sbjct: 604 QPATP-------AAATGEAAPVLTVQPAPQAP-----PAVSTPLPLGLQQPQAQQPPQAP 651
Query: 310 GSWKPGPPGSPRPWKSNPSASSGPWK-----PAKPAPSV--------------------- 343
PP + P + +P +S P K P P+
Sbjct: 652 TPQAAAPPQATTP-QPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLS 710
Query: 344 SPGPWKPIPS---VSPGPWKPTPSVSSASWKSSSV---SPSSWKSPPASPESWKSGPPEL 397
+ GP +P+ VS P P+ ++ K + + +P S SP +P+ + P L
Sbjct: 711 AEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAP--L 768
Query: 398 RKTAPTLSPEHWKAVP-PVSPELRKPGPPLSPEIRSPAGSPELRKPSGSPDLWKLSPDQR 456
+ P+ SP P SP L P P P R P+ + +P P L P Q
Sbjct: 769 KGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPS-RPPSRPQSVSRPPSEPPLHPCPPPQA 827
Query: 457 -KTSPA------SLDFPESQKSSRGGSPDLWKSSFFIEPQKPVFPETRKP-GPSGPSESP 508
T P L P + +P PQ P+ P+++ P GP P+
Sbjct: 828 PPTLPGIFVIQNQLGVPPPASNPAPTAPG--------PPQPPLRPQSQPPEGPLPPAPHL 879
Query: 509 KAASDIWKPVLSIDTEPRKPALFPEPAKTAPPASPEARKRALFPEPRKHALFPE 562
+S S +T R PA P + P S K P P H L PE
Sbjct: 880 PPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPT-PPPTLH-LVPE 931
Score = 52.8 bits (125), Expect = 1e-06
Identities = 98/446 (21%), Positives = 159/446 (35%), Gaps = 65/446 (14%)
Query: 144 ESPKPTPLTPLEPQKPGSVVSP----------ELQTPLPSPEPSKPASVSSPEPPKSVPV 193
+ P T PQ PG++ P + P P + + P +P
Sbjct: 425 KQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLP- 483
Query: 194 CESQKLAPVPSPEP-QKPAPVSPESVKATLSNPKPQKQSHF-PETLGP---PSASSPESP 248
Q+L+ +P+ Q A +P + ++NP Q+ P +LGP P + + +
Sbjct: 484 ---QQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAH 540
Query: 249 VLAASPEPWGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPAPAVS 308
+L+A+P G PA A + P +P+P+ P V+ P A +
Sbjct: 541 ILSAAPIQVG-QPALFQMPVSLAAGSLPTQSQPAPA-GPAATTVLQGVTLPPSAVAMLNT 598
Query: 309 P-GSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIP------SVSPGPWKP 361
P G +P P + + + P +PAP P P+P P P
Sbjct: 599 PDGLVQPATPAAA-------TGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAP 651
Query: 362 TPSVSSASWKSSSVSPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPELRK 421
TP ++ + +P +SPE G P L+ + + P +
Sbjct: 652 TPQAAAPP---QATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQE----R 704
Query: 422 PGPPLSPEIRSPAGSPELRKPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGSPDLWK 481
PLS E P L P+ + P + +PA+ P ++ + G +
Sbjct: 705 SQQPLSAE------GPHLSVPASV--IVSAPPPAQDPAPAT---PVAKGAGLGPQAPDSQ 753
Query: 482 SSFFIEPQKPVFPETRKPGPSGPSESPKAASDIWKPVLSIDTEPRKPALFPEPAKTAPPA 541
+S PQ P + PGPS P A P L P P T PP+
Sbjct: 754 ASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHL------------PSPHPTRPPS 801
Query: 542 SPEARKRALFPEPRKHALFPELPKSA 567
P +R +++ P + L P P A
Sbjct: 802 RPPSRPQSVSRPPSEPPLHPCPPPQA 827
Score = 41.2 bits (95), Expect = 0.004
Identities = 75/310 (24%), Positives = 118/310 (38%), Gaps = 80/310 (25%)
Query: 332 GPWKPAKPAPSVSPGPWKPIPSV-SPGPWKPTPSVSSASWKSSSVSPSSWKSPPASPESW 390
GP + P S P P P V G +PSV+ A SS S SS S +S ++
Sbjct: 1225 GPLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSAASSLDAD 1284
Query: 391 KSGPPELRKTAP-----------------------------TLSPEHWKAVPPVSPELRK 421
+ GP R P L P H PP + ++ +
Sbjct: 1285 EDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPPPPATLKVAE 1344
Query: 422 PGPPLSPEIRSPAG------------SPELRKPSGSPDLWKLSPDQRKTSPASLDFPESQ 469
P PP P P G +PE RKP G+ P RKT ++ P +
Sbjct: 1345 P-PPRPPPPPPPTGQMNGTVDHPPPAAPE-RKPLGTAPHCPRLP-LRKTYRENVGGPGAP 1401
Query: 470 KS-----SRGGSPDLWKSSFFIEPQKPVFPETRKPGPSGPSESPKAASDIWKPVLSIDTE 524
+ +RGGSP P+ P++ +A S + + + +++ E
Sbjct: 1402 EGTPAGRARGGSP------------APL-----------PAKVDEATSGLIRELAAVEDE 1438
Query: 525 PRKPALF---PEPAKTAPPAS--PEARKRALFPEPRKHALFPELPKSALFSESQKAVELG 579
+ L PEPA +A + P+ L P R+ + P++ +++ S+S + L
Sbjct: 1439 LYQRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLT 1498
Query: 580 DELQ--IDAI 587
+ LQ ID+I
Sbjct: 1499 EHLQSAIDSI 1508
Score = 39.7 bits (91), Expect = 0.011
Identities = 58/247 (23%), Positives = 80/247 (32%), Gaps = 56/247 (22%)
Query: 100 NKETDPVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKPTPLTPLEPQKP 159
N DPV PP P AEP P+P P P Q
Sbjct: 1324 NTALDPVHQPPPPP---ATLKVAEPP--------------------PRPPPPPPPTGQMN 1360
Query: 160 GSVVSPELQTPLPSPEPSKP------------ASVSSPEPPKSVPVCESQKLAPVPSPEP 207
G+V P P P + P +V P P+ P ++ +P P P
Sbjct: 1361 GTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAK 1420
Query: 208 ---------QKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSP----------ESP 248
++ A V E + L P P+ + + G P +P ESP
Sbjct: 1421 VDEATSGLIRELAAVEDELYQRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESP 1480
Query: 249 -VLAASPEPWGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPAPAV 307
V AS P E +SA S + +P +P P P A + P P P
Sbjct: 1481 DVDQASFSSDSPQDDTLTEHLQSA-IDSILNLQQAPGRTPAPSYPHAASAGTPASPPPLH 1539
Query: 308 SPGSWKP 314
P ++ P
Sbjct: 1540 RPEAYPP 1546
Score = 38.1 bits (87), Expect = 0.033
Identities = 55/231 (23%), Positives = 84/231 (36%), Gaps = 35/231 (15%)
Query: 185 PEPPKSVPVCESQKLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASS 244
P PP ++ V E P P P P P + + + T+ +P P P P
Sbjct: 1334 PPPPATLKVAE-------PPPRPPPPPPPTGQ-MNGTVDHPPPAAPERKPLGTAP---HC 1382
Query: 245 PESPVLAASPEPWGP--SPAASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPE--- 299
P P+ E G +P +P R + +P P K + S + AV E
Sbjct: 1383 PRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLI-RELAAVEDELYQ 1441
Query: 300 ------PRRPAPAVSPGS----WK-PGPPGSPRPWKSNPSASSGPWKPAKPAP-SVSPGP 347
P PA + + G+ W+ PG P + R +P + P +++
Sbjct: 1442 RMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHL 1501
Query: 348 WKPIPSV-----SPGPWKPTPSVSSASWKSSSVSPSSWKSPPASPESWKSG 393
I S+ +PG P PS A+ + SP P A P S +G
Sbjct: 1502 QSAIDSILNLQQAPGR-TPAPSYPHAASAGTPASPPPLHRPEAYPPSSHNG 1551
Score = 35.4 bits (80), Expect = 0.21
Identities = 43/200 (21%), Positives = 61/200 (30%), Gaps = 37/200 (18%)
Query: 137 LGSVLSPESPKPTPLTPLEPQKPGSVVSPELQTPLPSP-----------EPSKPASVSSP 185
L S P P + PQ G V+ L + + S P S
Sbjct: 263 LASAAGPSEPVTLASAGVSPQGAGLVIQKNLSAAVATTLNGNSVFGGAGAASAPTGTPSG 322
Query: 186 EPPKSVPVCESQKLAPVPS------PEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGP 239
+P P S L P P+ P P +P P K PKP
Sbjct: 323 QPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKP------------ 370
Query: 240 PSASSPESPVLAASPEPWGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPE 299
+P L EP A P+ K+ + + + P PA+
Sbjct: 371 ---FAPAGATLTIQGEP-----GALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQAN 422
Query: 300 PRRPAPAVSPGSWKPGPPGS 319
+ PA + G+ P PPG+
Sbjct: 423 VFKQPPATTTGAAPPQPPGA 442
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.127 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,445,166
Number of Sequences: 37866
Number of extensions: 3636035
Number of successful extensions: 66892
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1491
Number of HSP's successfully gapped in prelim test: 2978
Number of HSP's that attempted gapping in prelim test: 17676
Number of HSP's gapped (non-prelim): 26438
length of query: 812
length of database: 18,247,518
effective HSP length: 111
effective length of query: 701
effective length of database: 14,044,392
effective search space: 9845118792
effective search space used: 9845118792
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.