BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|40807485 PRP6 pre-mRNA processing factor 6 homolog [Homo sapiens] (941 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|40807485 PRP6 pre-mRNA processing factor 6 homolog [Homo sapi... 1902 0.0 gi|169172639 PREDICTED: similar to U5 snRNP-associated 102 kDa p... 806 0.0 gi|124256489 crooked neck-like 1 protein [Homo sapiens] 91 7e-18 gi|70980549 programmed cell death 11 [Homo sapiens] 53 2e-06 gi|156938331 PRP39 pre-mRNA processing factor 39 homolog [Homo s... 52 3e-06 gi|83415184 transmembrane and tetratricopeptide repeat containin... 48 5e-05 gi|55770906 XPA binding protein 2 [Homo sapiens] 47 1e-04 gi|4758472 G protein pathway suppressor 2 [Homo sapiens] 43 0.001 gi|21450645 tetratricopeptide repeat domain 16 [Homo sapiens] 42 0.002 gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 42 0.003 gi|112789538 troponin T3, skeletal, fast isoform 2 [Homo sapiens] 42 0.004 gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens] 41 0.006 gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens] 41 0.006 gi|148839339 nexilin (F actin binding protein) [Homo sapiens] 41 0.006 gi|4504487 histidine rich calcium binding protein precursor [Hom... 40 0.010 gi|5803203 troponin T3, skeletal, fast isoform 1 [Homo sapiens] 39 0.017 gi|24307965 UBX domain containing 2 [Homo sapiens] 39 0.017 gi|7110679 tetratricopeptide repeat domain 33 [Homo sapiens] 39 0.017 gi|56549694 enabled homolog isoform a [Homo sapiens] 39 0.023 gi|39930375 enabled homolog isoform b [Homo sapiens] 39 0.023 gi|116812573 CWC15 homolog [Homo sapiens] 39 0.023 gi|224809432 transmembrane and tetratricopeptide repeat containi... 39 0.023 gi|112789536 troponin T3, skeletal, fast isoform 3 [Homo sapiens] 39 0.030 gi|112789541 troponin T3, skeletal, fast isoform 4 [Homo sapiens] 39 0.030 gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 38 0.051 gi|7662078 tetratricopeptide repeat domain 37 [Homo sapiens] 37 0.066 gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 37 0.066 gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sap... 37 0.066 gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo sap... 37 0.066 gi|4505257 moesin [Homo sapiens] 37 0.087 >gi|40807485 PRP6 pre-mRNA processing factor 6 homolog [Homo sapiens] Length = 941 Score = 1902 bits (4927), Expect = 0.0 Identities = 941/941 (100%), Positives = 941/941 (100%) Query: 1 MNKKKKPFLGMPAPLGYVPGLGRGATGFTTRSDIGPARDANDPVDDRHAPPGKRTVGDQM 60 MNKKKKPFLGMPAPLGYVPGLGRGATGFTTRSDIGPARDANDPVDDRHAPPGKRTVGDQM Sbjct: 1 MNKKKKPFLGMPAPLGYVPGLGRGATGFTTRSDIGPARDANDPVDDRHAPPGKRTVGDQM 60 Query: 61 KKNQAADDDDEDLNDTNYDEFNGYAGSLFSSGPYEKDDEEADAIYAALDKRMDERRKERR 120 KKNQAADDDDEDLNDTNYDEFNGYAGSLFSSGPYEKDDEEADAIYAALDKRMDERRKERR Sbjct: 61 KKNQAADDDDEDLNDTNYDEFNGYAGSLFSSGPYEKDDEEADAIYAALDKRMDERRKERR 120 Query: 121 EQREKEEIEKYRMERPKIQQQFSDLKRKLAEVTEEEWLSIPEVGDARNKRQRNPRYEKLT 180 EQREKEEIEKYRMERPKIQQQFSDLKRKLAEVTEEEWLSIPEVGDARNKRQRNPRYEKLT Sbjct: 121 EQREKEEIEKYRMERPKIQQQFSDLKRKLAEVTEEEWLSIPEVGDARNKRQRNPRYEKLT 180 Query: 181 PVPDSFFAKHLQTGENHTSVDPRQTQFGGLNTPYPGGLNTPYPGGMTPGLMTPGTGELDM 240 PVPDSFFAKHLQTGENHTSVDPRQTQFGGLNTPYPGGLNTPYPGGMTPGLMTPGTGELDM Sbjct: 181 PVPDSFFAKHLQTGENHTSVDPRQTQFGGLNTPYPGGLNTPYPGGMTPGLMTPGTGELDM 240 Query: 241 RKIGQARNTLMDMRLSQVSDSVSGQTVVDPKGYLTDLNSMIPTHGGDINDIKKARLLLKS 300 RKIGQARNTLMDMRLSQVSDSVSGQTVVDPKGYLTDLNSMIPTHGGDINDIKKARLLLKS Sbjct: 241 RKIGQARNTLMDMRLSQVSDSVSGQTVVDPKGYLTDLNSMIPTHGGDINDIKKARLLLKS 300 Query: 301 VRETNPHHPPAWIASARLEEVTGKLQVARNLIMKGTEMCPKSEDVWLEAARLQPGDTAKA 360 VRETNPHHPPAWIASARLEEVTGKLQVARNLIMKGTEMCPKSEDVWLEAARLQPGDTAKA Sbjct: 301 VRETNPHHPPAWIASARLEEVTGKLQVARNLIMKGTEMCPKSEDVWLEAARLQPGDTAKA 360 Query: 361 VVAQAVRHLPQSVRIYIRAAELETDIRAKKRVLRKALEHVPNSVRLWKAAVELEEPEDAR 420 VVAQAVRHLPQSVRIYIRAAELETDIRAKKRVLRKALEHVPNSVRLWKAAVELEEPEDAR Sbjct: 361 VVAQAVRHLPQSVRIYIRAAELETDIRAKKRVLRKALEHVPNSVRLWKAAVELEEPEDAR 420 Query: 421 IMLSRAVECCPTSVELWLALARLETYENARKVLNKARENIPTDRHIWITAAKLEEANGNT 480 IMLSRAVECCPTSVELWLALARLETYENARKVLNKARENIPTDRHIWITAAKLEEANGNT Sbjct: 421 IMLSRAVECCPTSVELWLALARLETYENARKVLNKARENIPTDRHIWITAAKLEEANGNT 480 Query: 481 QMVEKIIDRAITSLRANGVEINREQWIQDAEECDRAGSVATCQAVMRAVIGIGIEEEDRK 540 QMVEKIIDRAITSLRANGVEINREQWIQDAEECDRAGSVATCQAVMRAVIGIGIEEEDRK Sbjct: 481 QMVEKIIDRAITSLRANGVEINREQWIQDAEECDRAGSVATCQAVMRAVIGIGIEEEDRK 540 Query: 541 HTWMEDADSCVAHNALECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRA 600 HTWMEDADSCVAHNALECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRA Sbjct: 541 HTWMEDADSCVAHNALECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRA 600 Query: 601 VAHCPKAEVLWLMGAKSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESENDEYER 660 VAHCPKAEVLWLMGAKSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESENDEYER Sbjct: 601 VAHCPKAEVLWLMGAKSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESENDEYER 660 Query: 661 ARRLLAKARSSAPTARVFMKSVKLEWVQDNIRAAQDLCEEALRHYEDFPKLWMMKGQIEE 720 ARRLLAKARSSAPTARVFMKSVKLEWVQDNIRAAQDLCEEALRHYEDFPKLWMMKGQIEE Sbjct: 661 ARRLLAKARSSAPTARVFMKSVKLEWVQDNIRAAQDLCEEALRHYEDFPKLWMMKGQIEE 720 Query: 721 QKEMMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGLW 780 QKEMMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGLW Sbjct: 721 QKEMMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGLW 780 Query: 781 LESVRLEYRAGLKNIANTLMAKALQECPNSGILWSEAIFLEARPQRRTKSVDALKKCEHD 840 LESVRLEYRAGLKNIANTLMAKALQECPNSGILWSEAIFLEARPQRRTKSVDALKKCEHD Sbjct: 781 LESVRLEYRAGLKNIANTLMAKALQECPNSGILWSEAIFLEARPQRRTKSVDALKKCEHD 840 Query: 841 PHVLLAVAKLFWSQRKITKAREWFHRTVKIDSDLGDAWAFFYKFELQHGTEEQQEEVRKR 900 PHVLLAVAKLFWSQRKITKAREWFHRTVKIDSDLGDAWAFFYKFELQHGTEEQQEEVRKR Sbjct: 841 PHVLLAVAKLFWSQRKITKAREWFHRTVKIDSDLGDAWAFFYKFELQHGTEEQQEEVRKR 900 Query: 901 CESAEPRHGELWCAVSKDIANWQKKIGDILRLVAGRIKNTF 941 CESAEPRHGELWCAVSKDIANWQKKIGDILRLVAGRIKNTF Sbjct: 901 CESAEPRHGELWCAVSKDIANWQKKIGDILRLVAGRIKNTF 941 >gi|169172639 PREDICTED: similar to U5 snRNP-associated 102 kDa protein [Homo sapiens] Length = 406 Score = 806 bits (2082), Expect = 0.0 Identities = 397/397 (100%), Positives = 397/397 (100%) Query: 545 EDADSCVAHNALECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRAVAHC 604 EDADSCVAHNALECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRAVAHC Sbjct: 10 EDADSCVAHNALECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRAVAHC 69 Query: 605 PKAEVLWLMGAKSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESENDEYERARRL 664 PKAEVLWLMGAKSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESENDEYERARRL Sbjct: 70 PKAEVLWLMGAKSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESENDEYERARRL 129 Query: 665 LAKARSSAPTARVFMKSVKLEWVQDNIRAAQDLCEEALRHYEDFPKLWMMKGQIEEQKEM 724 LAKARSSAPTARVFMKSVKLEWVQDNIRAAQDLCEEALRHYEDFPKLWMMKGQIEEQKEM Sbjct: 130 LAKARSSAPTARVFMKSVKLEWVQDNIRAAQDLCEEALRHYEDFPKLWMMKGQIEEQKEM 189 Query: 725 MEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESV 784 MEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESV Sbjct: 190 MEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESV 249 Query: 785 RLEYRAGLKNIANTLMAKALQECPNSGILWSEAIFLEARPQRRTKSVDALKKCEHDPHVL 844 RLEYRAGLKNIANTLMAKALQECPNSGILWSEAIFLEARPQRRTKSVDALKKCEHDPHVL Sbjct: 250 RLEYRAGLKNIANTLMAKALQECPNSGILWSEAIFLEARPQRRTKSVDALKKCEHDPHVL 309 Query: 845 LAVAKLFWSQRKITKAREWFHRTVKIDSDLGDAWAFFYKFELQHGTEEQQEEVRKRCESA 904 LAVAKLFWSQRKITKAREWFHRTVKIDSDLGDAWAFFYKFELQHGTEEQQEEVRKRCESA Sbjct: 310 LAVAKLFWSQRKITKAREWFHRTVKIDSDLGDAWAFFYKFELQHGTEEQQEEVRKRCESA 369 Query: 905 EPRHGELWCAVSKDIANWQKKIGDILRLVAGRIKNTF 941 EPRHGELWCAVSKDIANWQKKIGDILRLVAGRIKNTF Sbjct: 370 EPRHGELWCAVSKDIANWQKKIGDILRLVAGRIKNTF 406 Score = 106 bits (265), Expect = 9e-23 Identities = 98/402 (24%), Positives = 160/402 (39%), Gaps = 32/402 (7%) Query: 386 IRAKKRVLRKALEHVPNSVRLWKAAVELEEPEDAR----IMLSRAVECCPTSVELWLALA 441 + + + AL+ P+ +W A E+ R +L RAV CP + LWL A Sbjct: 21 LECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRAVAHCPKAEVLWLMGA 80 Query: 442 RLETYEN----ARKVLNKARENIPTDRHIWITAAKLEEANGNTQMVEKIIDRAITSLRAN 497 + + AR +L A + P IW+ A KLE N + +++ +A +S Sbjct: 81 KSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESENDEYERARRLLAKARSSAPTA 140 Query: 498 GVEIN--REQWIQDAEECDRAGSVATCQAVMRAVIGIGIEEEDRKHTWMEDADSCVAHNA 555 V + + +W+QD + + C+ +R ED WM Sbjct: 141 RVFMKSVKLEWVQD----NIRAAQDLCEEALR-------HYEDFPKLWMMKGQIEEQKEM 189 Query: 556 LECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRAVAHCPKAEVLWLMGA 615 +E AR Y L+ P +WL + E+ G A+L+++ PK LWL Sbjct: 190 MEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESV 249 Query: 616 KSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESENDEYERARRLLAKARSSAPTA 675 + ++ AG A +++A A Q PNS +W A+ LE+ ++ L K Sbjct: 250 RLEYRAGLKNIANTLMAKALQECPNSGILWSEAIFLEARPQRRTKSVDALKKCEHD---P 306 Query: 676 RVFMKSVKLEWVQDNIRAAQDLCEEALRHYEDFPKLWMMKGQIEEQKEMMEKAREAYNQG 735 V + KL W Q I A++ ++ D W + E Q E+ E + Sbjct: 307 HVLLAVAKLFWSQRKITKAREWFHRTVKIDSDLGDAWAFFYKFELQHGTEEQQEEVRKRC 366 Query: 736 LKKCPHSTPLWLLLSR----LEEKIGQLTRARAILEKSRLKN 773 P LW +S+ ++KIG + R L R+KN Sbjct: 367 ESAEPRHGELWCAVSKDIANWQKKIGDILR----LVAGRIKN 404 Score = 87.4 bits (215), Expect = 6e-17 Identities = 85/376 (22%), Positives = 150/376 (39%), Gaps = 60/376 (15%) Query: 289 NDIKKARLLLKSVRETNPHHPPAWIASARLEEVTGKLQVARNLIMKGTEMCPKSEDVWLE 348 N ++ AR + + P W+ +A E+ G + L+ + CPK+E +WL Sbjct: 19 NALECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRAVAHCPKAEVLWLM 78 Query: 349 AARLQ--PGD--TAKAVVAQAVRHLPQSVRIYIRAAELETD------------------- 385 A+ + GD A++++A A + P S I++ A +LE++ Sbjct: 79 GAKSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESENDEYERARRLLAKARSSAP 138 Query: 386 -----------------IRAKKRVLRKALEHVPNSVRLWKAAVELEEP----EDARIMLS 424 IRA + + +AL H + +LW ++EE E AR + Sbjct: 139 TARVFMKSVKLEWVQDNIRAAQDLCEEALRHYEDFPKLWMMKGQIEEQKEMMEKAREAYN 198 Query: 425 RAVECCPTSVELWLALARLE----TYENARKVLNKARENIPTDRHIWITAAKLEEANGNT 480 + ++ CP S LWL L+RLE AR +L K+R P + +W+ + +LE G Sbjct: 199 QGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESVRLEYRAGLK 258 Query: 481 QMVEKIIDRAITSLRANGVEINREQWIQDAEECDRAGSVATCQAVMRAVIGIGIEEEDRK 540 + ++ +A+ +G+ + E +A R SV + E Sbjct: 259 NIANTLMAKALQECPNSGI-LWSEAIFLEARPQRRTKSVDALKKC-----------EHDP 306 Query: 541 HTWMEDADSCVAHNALECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRA 600 H + A + + AR + +++ W FE HGT E E + +R Sbjct: 307 HVLLAVAKLFWSQRKITKAREWFHRTVKIDSDLGDAWAFFYKFELQHGTEEQQEEVRKRC 366 Query: 601 VAHCPKAEVLWLMGAK 616 + P+ LW +K Sbjct: 367 ESAEPRHGELWCAVSK 382 Score = 54.3 bits (129), Expect = 5e-07 Identities = 40/166 (24%), Positives = 69/166 (41%), Gaps = 15/166 (9%) Query: 288 INDIKKARLLLKSVRETNPHHPPAWIASARLEEVTGKLQVARNLIMKGTEMCPKSEDVWL 347 I + +AR +L+ R NP +P W+ S RLE G +A L+ K + CP S +W Sbjct: 221 IGQLTRARAILEKSRLKNPKNPGLWLESVRLEYRAGLKNIANTLMAKALQECPNSGILWS 280 Query: 348 EAARLQPGDTAKAVVAQAVRHLPQSVRIYIRAAELETDIRAKKRVLRKALEHVPNSVRL- 406 EA L+ + A++ + + A+L +R + KA E +V++ Sbjct: 281 EAIFLEARPQRRTKSVDALKKCEHDPHVLLAVAKLFW----SQRKITKAREWFHRTVKID 336 Query: 407 ----------WKAAVELEEPEDARIMLSRAVECCPTSVELWLALAR 442 +K ++ E + R P ELW A+++ Sbjct: 337 SDLGDAWAFFYKFELQHGTEEQQEEVRKRCESAEPRHGELWCAVSK 382 >gi|124256489 crooked neck-like 1 protein [Homo sapiens] Length = 848 Score = 90.5 bits (223), Expect = 7e-18 Identities = 113/502 (22%), Positives = 222/502 (44%), Gaps = 52/502 (10%) Query: 312 WIASARLEEVTGKLQVARNLIMKGTEMCPKSEDVWLEAARLQPGDT----AKAVVAQAVR 367 WI A+ EE ++Q AR++ + ++ ++ +WL+ A ++ + A+ + +A+ Sbjct: 245 WIKYAQWEESLKEIQRARSIYERALDVDYRNITLWLKYAEMEMKNRQVNHARNIWDRAIT 304 Query: 368 HLPQSVRIYIRAAELET---DIRAKKRVLRKALEHVPNSVRLWKAAVELE----EPEDAR 420 LP+ + + + +E ++ ++V + +E P + W + + E E + AR Sbjct: 305 TLPRVNQFWYKYTYMEEMLGNVAGARQVFERWMEWQPEE-QAWHSYINFELRYKEVDRAR 363 Query: 421 IMLSRAVECCPTSVELWLALARLET----YENARKVLNKARE---NIPTDRHIWITAAKL 473 + R V P V+ W+ AR E + +ARKV +A E + D H+++ AK Sbjct: 364 TIYERFVLVHP-DVKNWIKYARFEEKHAYFAHARKVYERAVEFFGDEHMDEHLYVAFAKF 422 Query: 474 EEANGNTQMVEKIIDRAITSL-RANGVEINREQWIQDAEECDRAGSVATCQAVMRAVIGI 532 EE + V I A+ + + + E+ + I + + DR G + ++ + Sbjct: 423 EENQKEFERVRVIYKYALDRISKQDAQELFKNYTIFEKKFGDRRG----IEDIIVSKRRF 478 Query: 533 GIEEEDRKH-----TWMEDADSCVAHNALECARAIYAYALQVFP--SKKSVWLRAAYFEK 585 EEE + + W + + E R +Y A+ P +K W R Y Sbjct: 479 QYEEEVKANPHNYDAWFDYLRLVESDAEAEAVREVYERAIANVPPIQEKRHWKRYIYLWI 538 Query: 586 NHGTRESLEA--------LLQRAVAHCPKAEV----LWLMGAKSKWLAGDVPAARSILAL 633 N+ E LEA + Q ++ P + +W++ A+ + ++ AR L Sbjct: 539 NYALYEELEAKDPERTRQVYQASLELIPHKKFTFAKMWILYAQFEIRQKNLSLARRALGT 598 Query: 634 AFQANPNSEEIWLAAVKLESENDEYERARRLLAKARSSAP-TARVFMKSVKLEWVQDNIR 692 + P + +++ ++LE + E++R R+L K P ++K +LE + +I Sbjct: 599 SIGKCPKN-KLFKVYIELELQLREFDRCRKLYEKFLEFGPENCTSWIKFAELETILGDID 657 Query: 693 AAQDLCEEALRHYE-DFPK-LWMMKGQIEEQKEMMEKAREAYNQGLKKCPHSTPLWLLLS 750 A+ + E A+ D P+ LW E ++E E+ R Y + L++ H +W+ + Sbjct: 658 RARAIYELAISQPRLDMPEVLWKSYIDFEIEQEETERTRNLYRRLLQRTQH-VKVWISFA 716 Query: 751 RLE---EKIGQLTRARAILEKS 769 + E K G LT+ R I E++ Sbjct: 717 QFELSSGKEGSLTKCRQIYEEA 738 Score = 45.8 bits (107), Expect = 2e-04 Identities = 43/214 (20%), Positives = 89/214 (41%), Gaps = 5/214 (2%) Query: 691 IRAAQDLCEEALRHYEDFPKLWMMKGQIEEQ-KEMMEKAREAYNQGLKKCPHSTPLWLLL 749 I A Q L E R E P K EE+ + + R+ + ++K W+ Sbjct: 189 ITAEQLLREAKERELELLPPPPQQKITDEEELNDYKLRKRKTFEDNIRKNRTVISNWIKY 248 Query: 750 SRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESVRLEYRAGLKNIANTLMAKALQECPN 809 ++ EE + ++ RAR+I E++ + +N LWL+ +E + N A + +A+ P Sbjct: 249 AQWEESLKEIQRARSIYERALDVDYRNITLWLKYAEMEMKNRQVNHARNIWDRAITTLPR 308 Query: 810 SGILWSEAIFLE---ARPQRRTKSVDALKKCEHDPHVLLAVAKLFWSQRKITKAREWFHR 866 W + ++E + + + + + + +++ +AR + R Sbjct: 309 VNQFWYKYTYMEEMLGNVAGARQVFERWMEWQPEEQAWHSYINFELRYKEVDRARTIYER 368 Query: 867 TVKIDSDLGDAWAFFYKFELQHGTEEQQEEVRKR 900 V + D+ + W + +FE +H +V +R Sbjct: 369 FVLVHPDVKN-WIKYARFEEKHAYFAHARKVYER 401 >gi|70980549 programmed cell death 11 [Homo sapiens] Length = 1871 Score = 52.8 bits (125), Expect = 2e-06 Identities = 37/200 (18%), Positives = 81/200 (40%), Gaps = 7/200 (3%) Query: 599 RAVAHCPKAEVLWLMGAKSKWLAGDVPAARSIL-----ALAFQANPNSEEIWLAAVKLES 653 R V P + +LWL A ++ AR++ ++F+ +W+A + LE+ Sbjct: 1610 RLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFREEQEKLNVWVALLNLEN 1669 Query: 654 ENDEYERARRLLAKARSSAPTARVFMKSVKLEWVQDNIRAAQDLCEEALRHYEDFPKLWM 713 E ++ +A +VF+ + + + A +L L+ + +W+ Sbjct: 1670 MYGSQESLTKVFERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRFRQEKAVWI 1729 Query: 714 MKGQIEEQKEMMEKAREAYNQGLKKCPHSTPLWLL--LSRLEEKIGQLTRARAILEKSRL 771 G ++ + + L+ P + ++ ++LE ++G RA+AI E + Sbjct: 1730 KYGAFLLRRSQAAASHRVLQRALECLPSKEHVDVIAKFAQLEFQLGDAERAKAIFENTLS 1789 Query: 772 KNPKNPGLWLESVRLEYRAG 791 PK +W + + + G Sbjct: 1790 TYPKRTDVWSVYIDMTIKHG 1809 Score = 41.2 bits (95), Expect = 0.005 Identities = 114/600 (19%), Positives = 226/600 (37%), Gaps = 92/600 (15%) Query: 8 FLGMPAPLGYVPGLGRGATGFTTRSDIGPARDANDPVDDRHAPPGKRTVGDQMKKNQAAD 67 ++G P G LG G S + + + ++H P GK ++ N + Sbjct: 1330 YVGSIQPHGVFFRLGPSVVGLARYSHVSQHSPSKKALYNKHLPEGKLLTARVLRLNHQKN 1389 Query: 68 DDDEDL--NDTNYDEF--NGYAGSLFSSGPYEKDDEEADAIYAALDKRMDERRKERREQR 123 + DT + G L + + EE D ++ +++R E++ Q+ Sbjct: 1390 LVELSFLPGDTGKPDVLSASLEGQLTKQEERKTEAEERD----QKGEKKNQKRNEKKNQK 1445 Query: 124 EKEEIEKYRMERPKIQQQFSDLKRKLAEVTEEEWLSIPEVGDARNKRQRNPRYEKLTPVP 183 +EE+E E+ + Q+ + KR E E G + + + P+ L+ Sbjct: 1446 GQEEVEMPSKEKQQPQKPQAQ-KRGGRECRES--------GSEQERVSKKPKKAGLSEED 1496 Query: 184 DSFFAKHLQTGE---NHTSVDPRQTQFGGLNTPYPGGLNTPYPGGMTPGLMTPGTGELDM 240 DS + + G+ T+V P++ Q P L++ + + +TP Sbjct: 1497 DSLVDVYYREGKEEAEETNVLPKEKQTKPAEAPRL-QLSSGFAWNVGLDSLTPALPP--- 1552 Query: 241 RKIGQARNTLMDMRLSQVSDSVSGQTVVDPKGYLTDLNSMIPTHGGDINDIKKARLLLKS 300 L++ SDS + H I KK R L K Sbjct: 1553 --------------LAESSDSEEDE----------------KPHQATIKKSKKERELEKQ 1582 Query: 301 VRETNPHHPPAWIASARLEEV---TGKLQVARNLIMKGTEMCPKSEDVWLE--AARLQPG 355 E +R+EE G+ + + + P S +WL+ A LQ Sbjct: 1583 KAEKE---------LSRIEEALMDPGRQPESADDFDRLVLSSPNSSILWLQYMAFHLQAT 1633 Query: 356 --DTAKAVVAQAV-----RHLPQSVRIYIRAAELETDIRAKK---RVLRKALEH-VPNSV 404 + A+AV +A+ R + + +++ LE +++ +V +A+++ P V Sbjct: 1634 EIEKARAVAERALKTISFREEQEKLNVWVALLNLENMYGSQESLTKVFERAVQYNEPLKV 1693 Query: 405 RLWKAAV--ELEEPEDARIMLSRAVECCPTSVELWLA----LARLETYENARKVLNKARE 458 L A + + E+ ++A + +R ++ +W+ L R + +VL +A E Sbjct: 1694 FLHLADIYAKSEKFQEAGELYNRMLKRFRQEKAVWIKYGAFLLRRSQAAASHRVLQRALE 1753 Query: 459 NIPTDRHIWITA--AKLEEANGNTQMVEKIIDRAITSLRANGVEINREQWIQDAEECDRA 516 +P+ H+ + A A+LE G+ + + I + +++ + W + + Sbjct: 1754 CLPSKEHVDVIAKFAQLEFQLGDAERAKAIFENTLSTYPK-----RTDVWSVYIDMTIKH 1808 Query: 517 GSVATCQAVMRAVIGIGIEEEDRKHTWMEDADSCVAHNALECARAIYAYALQVFPSKKSV 576 GS + + VI + + + K + D H + +A+ A AL+ +K SV Sbjct: 1809 GSQKDVRDIFERVIHLSLAPKRMKFFFKRYLDYEKQHGTEKDVQAVKAKALEYVEAKSSV 1868 Score = 40.0 bits (92), Expect = 0.010 Identities = 44/244 (18%), Positives = 100/244 (40%), Gaps = 17/244 (6%) Query: 371 QSVRIYIRAAELETDIRAKKRVLRK-ALEHVPNSVRLWKAAVELEEPEDARIMLSRAVEC 429 Q + +++A E+E +R L+ + + +W A + LE ++ L++ E Sbjct: 1624 QYMAFHLQATEIEKARAVAERALKTISFREEQEKLNVWVALLNLENMYGSQESLTKVFER 1683 Query: 430 C-----PTSVELWLA--LARLETYENARKVLNKARENIPTDRHIWITAAKLEEANGNTQM 482 P V L LA A+ E ++ A ++ N+ + ++ +WI Sbjct: 1684 AVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRFRQEKAVWIKYGAFLLRRSQAAA 1743 Query: 483 VEKIIDRAITSLRANGVEINREQWIQDAEECDRAGSVATCQAVMRAVIGIGIEEEDRKHT 542 +++ RA+ L + + + + A+ + G +A+ + + D Sbjct: 1744 SHRVLQRALECLPSKE---HVDVIAKFAQLEFQLGDAERAKAIFENTLSTYPKRTD---V 1797 Query: 543 WMEDADSCVAHNALECARAIYAYALQVFPSKKSV---WLRAAYFEKNHGTRESLEALLQR 599 W D + H + + R I+ + + + K + + R +EK HGT + ++A+ + Sbjct: 1798 WSVYIDMTIKHGSQKDVRDIFERVIHLSLAPKRMKFFFKRYLDYEKQHGTEKDVQAVKAK 1857 Query: 600 AVAH 603 A+ + Sbjct: 1858 ALEY 1861 Score = 33.1 bits (74), Expect = 1.2 Identities = 41/213 (19%), Positives = 80/213 (37%), Gaps = 18/213 (8%) Query: 401 PNSVRLWKAAV----ELEEPEDARIMLSRAVECCPTSVE-----LWLALARLETYENARK 451 PNS LW + + E E AR + RA++ E +W+AL LE +++ Sbjct: 1616 PNSSILWLQYMAFHLQATEIEKARAVAERALKTISFREEQEKLNVWVALLNLENMYGSQE 1675 Query: 452 VLNKARENIPTDRH---IWITAAKLEEANGNTQMVEKIIDRAITSLRANGVEINREQWIQ 508 L K E +++ A + + Q ++ +R + R + WI+ Sbjct: 1676 SLTKVFERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRFRQE-----KAVWIK 1730 Query: 509 DAEECDRAGSVATCQAVMRAVIGIGIEEEDRKHTWMEDADSCVAHNALECARAIYAYALQ 568 R A V++ + + ++ + A E A+AI+ L Sbjct: 1731 YGAFLLRRSQAAASHRVLQRALEC-LPSKEHVDVIAKFAQLEFQLGDAERAKAIFENTLS 1789 Query: 569 VFPSKKSVWLRAAYFEKNHGTRESLEALLQRAV 601 +P + VW HG+++ + + +R + Sbjct: 1790 TYPKRTDVWSVYIDMTIKHGSQKDVRDIFERVI 1822 Score = 32.7 bits (73), Expect = 1.6 Identities = 39/202 (19%), Positives = 76/202 (37%), Gaps = 14/202 (6%) Query: 711 LWMMKGQIEEQKEMMEKAREAYNQGLKKCP-----HSTPLWLLLSRLEEKIGQLTRARAI 765 LW+ Q +EKAR + LK +W+ L LE G + Sbjct: 1621 LWLQYMAFHLQATEIEKARAVAERALKTISFREEQEKLNVWVALLNLENMYGSQESLTKV 1680 Query: 766 LEKSRLKNPKNPGLWLESVRLEYRAGLKNIANTLMAKALQECPNSGILWSE-AIFLEARP 824 E++ N ++L + ++ A L + L+ +W + FL R Sbjct: 1681 FERAVQYNEPLK-VFLHLADIYAKSEKFQEAGELYNRMLKRFRQEKAVWIKYGAFLLRRS 1739 Query: 825 QRRT------KSVDALKKCEHDPHVLLAVAKLFWSQRKITKAREWFHRTVKIDSDLGDAW 878 Q ++++ L EH V+ A+L + +A+ F T+ D W Sbjct: 1740 QAAASHRVLQRALECLPSKEH-VDVIAKFAQLEFQLGDAERAKAIFENTLSTYPKRTDVW 1798 Query: 879 AFFYKFELQHGTEEQQEEVRKR 900 + + ++HG+++ ++ +R Sbjct: 1799 SVYIDMTIKHGSQKDVRDIFER 1820 Score = 32.7 bits (73), Expect = 1.6 Identities = 37/181 (20%), Positives = 70/181 (38%), Gaps = 15/181 (8%) Query: 543 WMEDADSCVAHNALECARAIYAYALQVFP-----SKKSVWLRAAYFEKNHGTRESLEALL 597 W++ + +E ARA+ AL+ K +VW+ E +G++ESL + Sbjct: 1622 WLQYMAFHLQATEIEKARAVAERALKTISFREEQEKLNVWVALLNLENMYGSQESLTKVF 1681 Query: 598 QRAVAHCPKAEVLWLMG---AKSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESE 654 +RAV + +V + AKS+ A + + + +W+ Sbjct: 1682 ERAVQYNEPLKVFLHLADIYAKSE----KFQEAGELYNRMLKRFRQEKAVWIKYGAFLLR 1737 Query: 655 NDEYERARRLLAKARSSAPTAR---VFMKSVKLEWVQDNIRAAQDLCEEALRHYEDFPKL 711 + + R+L +A P+ V K +LE+ + A+ + E L Y + Sbjct: 1738 RSQAAASHRVLQRALECLPSKEHVDVIAKFAQLEFQLGDAERAKAIFENTLSTYPKRTDV 1797 Query: 712 W 712 W Sbjct: 1798 W 1798 >gi|156938331 PRP39 pre-mRNA processing factor 39 homolog [Homo sapiens] Length = 669 Score = 52.0 bits (123), Expect = 3e-06 Identities = 89/438 (20%), Positives = 158/438 (36%), Gaps = 63/438 (14%) Query: 377 IRAAELETDIRAKKRVLRKALEHVPNSVRLWKAAVELEEPED----ARIMLSRAVECCPT 432 ++ E E + A ++ + H P WK +LE+ D + + R ++ P Sbjct: 102 LQYVEQENHLMAARKAFDRFFIHYPYCYGYWKKYADLEKRHDNIKPSDEVYRRGLQAIPL 161 Query: 433 SVELWLALARL----------ETYENARKVLNKARENIPTD---RHIWITAAKLEEANGN 479 SV+LW+ ET R A TD +W E GN Sbjct: 162 SVDLWIHYINFLKETLDPGDPETNNTIRGTFEHAVLAAGTDFRSDRLWEMYINWENEQGN 221 Query: 480 TQMVEKIIDRAI---TSLRANGVE--------------INREQWIQDAEECDRAGSVATC 522 + V I DR + T L ++ + + EQ+IQ E + Sbjct: 222 LREVTAIYDRILGIPTQLYSHHFQRFKEHVQNNLPRDLLTGEQFIQLRRELASVNGHSGD 281 Query: 523 QAVMRAVIGIGIEE-----------EDRKHTWMEDADSCVAHNALECAR------AIYAY 565 + GIE+ E+ +H +E +N E ++ I Sbjct: 282 DGPPGDDLPSGIEDITDPAKLITEIENMRHRIIEIHQEMFNYNEHEVSKRWTFEEGIKRP 341 Query: 566 ALQVFPSKKSV---WLRAAYFEKNHGTRESLEALLQRAVAHCPKAEVLWLMGAKSKWLAG 622 V P +K+ W FE +GT E + L +R V C E W+ AK Sbjct: 342 YFHVKPLEKAQLKNWKEYLEFEIENGTHERVVVLFERCVISCALYEEFWIKYAK-YMENH 400 Query: 623 DVPAARSILALAFQAN-PNSEEIWLAAVKLESENDEYERARRLLAKARSSA-PTARVFMK 680 + R + + A + P + + E + AR +L A V ++ Sbjct: 401 SIEGVRHVFSRACTIHLPKKPMVHMLWAAFEEQQGNINEARNILKTFEECVLGLAMVRLR 460 Query: 681 SVKLEWVQDNIRAAQDLCEEALRHYE-----DFPKLWMMKGQIEEQKEMMEKAREAYNQG 735 V LE N+ A+ L ++A+++ + F + + + + QK + K+R+ + Sbjct: 461 RVSLERRHGNLEEAEHLLQDAIKNAKSNNESSFYAVKLARHLFKIQKN-LPKSRKVLLEA 519 Query: 736 LKKCPHSTPLWLLLSRLE 753 +++ +T L+L L +E Sbjct: 520 IERDKENTKLYLNLLEME 537 Score = 32.7 bits (73), Expect = 1.6 Identities = 37/176 (21%), Positives = 71/176 (40%), Gaps = 19/176 (10%) Query: 576 VWLRAAYFEKNHGTRESLEALLQRAVAHCPKAEVLWLMGAKSK----WLAGDVPAARSIL 631 V LR E+ HG E E LLQ A+ + K + ++P +R +L Sbjct: 457 VRLRRVSLERRHGNLEEAEHLLQDAIKNAKSNNESSFYAVKLARHLFKIQKNLPKSRKVL 516 Query: 632 ALAFQANPNSEEIWLAAVKLESENDEYERARRLL----AKARSSAP-TARVFMKSVKLEW 686 A + + + +++L +++E D + +L S P R+ K+E+ Sbjct: 517 LEAIERDKENTKLYLNLLEMEYSGDLKQNEENILNCFDKAVHGSLPIKMRITFSQRKVEF 576 Query: 687 VQDNIRAAQDLCEEALRHYEDFPKLWMMKGQIEEQKEMMEKAREAYNQGLKKCPHS 742 ++D D+ + L Y++ L ++EQ + KA + +K H+ Sbjct: 577 LED---FGSDV-NKLLNAYDEHQTL------LKEQDSLKRKAENGSEEPEEKKAHT 622 >gi|83415184 transmembrane and tetratricopeptide repeat containing 1 [Homo sapiens] Length = 774 Score = 47.8 bits (112), Expect = 5e-05 Identities = 49/220 (22%), Positives = 93/220 (42%), Gaps = 10/220 (4%) Query: 557 ECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRAVAHCPKAEVLWLMGAK 616 E A A Y A+++ PS + ++ G E +RA+ KAE+L +GA Sbjct: 525 EKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVAHKAEILSPLGAL 584 Query: 617 SKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLES---ENDEYERARRLLAKARSSAP 673 + G A I A P+ E+ LA ++ + + E E+ + + Sbjct: 585 Y-YNTGRYEEALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIVSEETGCL 643 Query: 674 TARVFMKSVKLEWVQDNIRAAQDLCEEALRHYEDFPK----LWMMKGQIEEQKEMMEKAR 729 + ++ + Q+N A D ++AL+ PK L+ KG ++ +++KA Sbjct: 644 ECYRLLSAIYSK--QENHDKALDAIDKALQLKPKDPKVISELFFTKGNQLREQNLLDKAF 701 Query: 730 EAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKS 769 E+Y ++ P W+ + ++ G+ ARA E++ Sbjct: 702 ESYRVAVQLNPDQAQAWMNMGGIQHIKGKYVSARAYYERA 741 Score = 42.0 bits (97), Expect = 0.003 Identities = 74/364 (20%), Positives = 133/364 (36%), Gaps = 53/364 (14%) Query: 561 AIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRAVAHCPK-AEVLWLMGAKSKW 619 +++ +Q P V A F K+ G + + A+ P+ A L +G Sbjct: 362 SLFRSGVQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGT---- 417 Query: 620 LAGDVPAARSILALAFQANPNSEEIWLAAVKLESENDEYERARRLLAKARSSAPT-ARVF 678 L D A+ A Q +P L ++ E A LL + P A + Sbjct: 418 LTRDTAEAKMYYQRALQLHPQHNRALFNLGNLLKSQEKKEEAITLLKDSIKYGPEFADAY 477 Query: 679 MKSVKLEWVQDNIRAAQDLCEEALRHYEDFPKLWMMKGQIEEQKEMMEKAREAYNQGLKK 738 L Q+ + A+++ + +++ D L G + EKA Y Q +K Sbjct: 478 SSLASLLAEQERFKEAEEIYQTGIKNCPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKL 537 Query: 739 CPHSTPLWLLLSRLEEKIGQ-------LTRARAILEKSRLKNP-----KNPGLWLESVRL 786 P + L RL +G+ RA + K+ + +P N G + E++++ Sbjct: 538 SPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVAHKAEILSPLGALYYNTGRYEEALQI 597 Query: 787 ------------EYRAGLKNIANTLMAKALQECPNSGILWSEAIFLE---------ARPQ 825 E R L + + E + I+ E LE ++ + Sbjct: 598 YQEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIVSEETGCLECYRLLSAIYSKQE 657 Query: 826 RRTKSVDALKKC----EHDPHVLLAVAKLFWS-------QRKITKAREWFHRTVKIDSDL 874 K++DA+ K DP V +++LF++ Q + KA E + V+++ D Sbjct: 658 NHDKALDAIDKALQLKPKDPKV---ISELFFTKGNQLREQNLLDKAFESYRVAVQLNPDQ 714 Query: 875 GDAW 878 AW Sbjct: 715 AQAW 718 Score = 35.4 bits (80), Expect = 0.25 Identities = 66/356 (18%), Positives = 133/356 (37%), Gaps = 33/356 (9%) Query: 280 MIPTHGGDIN-------DIKKARLLLKSVRETNPHHPPAWIASARLEEVTGKLQVARNLI 332 + P H +N D +A++ + + +P H A L + K + A L+ Sbjct: 404 LYPRHASALNNLGTLTRDTAEAKMYYQRALQLHPQHNRALFNLGNLLKSQEKKEEAITLL 463 Query: 333 MKGTEMCPKSEDVWLEAARL----QPGDTAKAVVAQAVRHLPQSVRIY-------IRAAE 381 + P+ D + A L + A+ + +++ P S ++ + Sbjct: 464 KDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTGIKNCPDSSDLHNNYGVFLVDTGL 523 Query: 382 LETDIRAKKRVLRKALEHVPNSVRLWKAAVELEEPEDARIMLSRAVECCPTSVELWLALA 441 E + ++ ++ + H V L + L E A RA++ + E+ L Sbjct: 524 PEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVAHKA-EILSPLG 582 Query: 442 RLE----TYENARKVLNKARENIPTDRHIWITAAKLEEANGNTQMVEKIIDRAITSLRAN 497 L YE A ++ +A P+ R + + A++ G T+ EK+ + I S Sbjct: 583 ALYYNTGRYEEALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNH-IVSEETG 641 Query: 498 GVEINREQWIQDAEECDRAGSVATCQAVMRAVIGIGIEEEDRK---HTWMEDADSCVAHN 554 +E R + A + A+ +A + ++ +D K + + N Sbjct: 642 CLECYR---LLSAIYSKQENHDKALDAIDKA---LQLKPKDPKVISELFFTKGNQLREQN 695 Query: 555 ALECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRAVAHCPKAEVL 610 L+ A Y A+Q+ P + W+ + G S A +RA+ P +++L Sbjct: 696 LLDKAFESYRVAVQLNPDQAQAWMNMGGIQHIKGKYVSARAYYERALQLVPDSKLL 751 >gi|55770906 XPA binding protein 2 [Homo sapiens] Length = 855 Score = 46.6 bits (109), Expect = 1e-04 Identities = 77/332 (23%), Positives = 134/332 (40%), Gaps = 41/332 (12%) Query: 606 KAEVLWLMGAKSKWLAGDVPAARSILALAFQAN----PNSEEIWLAAVKLESENDEYERA 661 K LW+ AK G + AR IL A + N + +W +LE ++ Y+ A Sbjct: 393 KPHTLWVAFAKFYEDNGQLDDARVILEKATKVNFKQVDDLASVWCQCGELELRHENYDEA 452 Query: 662 RRLLAKARS-----------SAPTARVFMKSVKLEWVQDNIRAAQDLCEEALRHYEDFPK 710 RLL KA + S P KS+K+ + ++ + + Y+ Sbjct: 453 LRLLRKATALPARRAEYFDGSEPVQNRVYKSLKVWSMLADLEESLGTFQSTKAVYDRILD 512 Query: 711 LWMMKGQIE-------EQKEMMEKAREAYNQGLK--KCPHSTPLW-LLLSRLEEKIG--Q 758 L + QI E+ + E++ +AY +G+ K P+ + +W L++ + G + Sbjct: 513 LRIATPQIVINYAMFLEEHKYFEESFKAYERGISLFKWPNVSDIWSTYLTKFIARYGGRK 572 Query: 759 LTRARAILEKSRLKNPKNPG--LWLESVRLEYRAGLKNIANTLMAKAL------QECPNS 810 L RAR + E++ P L+L +LE GL A + +A Q+ Sbjct: 573 LERARDLFEQALDGCPPKYAKTLYLLYAQLEEEWGLARHAMAVYERATRAVEPAQQYDMF 632 Query: 811 GILWSEAIFLEARPQRR---TKSVDALKKCEHDPHVLLAVAKLFWSQRKITKAREWFHRT 867 I A + R K+++ L EH + L A + +I +AR + Sbjct: 633 NIYIKRAAEIYGVTHTRGIYQKAIEVLSD-EHAREMCLRFADMECKLGEIDRARAIYSFC 691 Query: 868 VKI--DSDLGDAWAFFYKFELQHGTEEQQEEV 897 +I G W + FE++HG E+ +E+ Sbjct: 692 SQICDPRTTGAFWQTWKDFEVRHGNEDTIKEM 723 Score = 39.3 bits (90), Expect = 0.017 Identities = 90/434 (20%), Positives = 176/434 (40%), Gaps = 55/434 (12%) Query: 288 INDIKKARLLLKSVRETNPHHPPAWIASARLEEVTGKLQVARNLIMKGTEMCPKSED--- 344 IN +A + + T H W+A A+ E G+L AR ++ K T++ K D Sbjct: 375 INTYTEAVQTVDPFKATGKPHT-LWVAFAKFYEDNGQLDDARVILEKATKVNFKQVDDLA 433 Query: 345 -VWLEAARL----QPGDTAKAVVAQAV-----------------RHLPQSVRIYIRAAEL 382 VW + L + D A ++ +A + +S++++ A+L Sbjct: 434 SVWCQCGELELRHENYDEALRLLRKATALPARRAEYFDGSEPVQNRVYKSLKVWSMLADL 493 Query: 383 ETDI---RAKKRVLRKALE-HVPNSVRLWKAAVELEEP---EDARIMLSRAVEC--CPTS 433 E + ++ K V + L+ + + A+ LEE E++ R + P Sbjct: 494 EESLGTFQSTKAVYDRILDLRIATPQIVINYAMFLEEHKYFEESFKAYERGISLFKWPNV 553 Query: 434 VELWLA-----LARL--ETYENARKVLNKARENIPTD--RHIWITAAKLEEANGNTQMVE 484 ++W +AR E AR + +A + P + +++ A+LEE G + Sbjct: 554 SDIWSTYLTKFIARYGGRKLERARDLFEQALDGCPPKYAKTLYLLYAQLEEEWGLARHAM 613 Query: 485 KIIDRAITSLRANGVEINREQWIQDAEECDRAGSVATCQAVMRAVIGIGIEEEDRKHTWM 544 + +RA ++ +I+ A E V + + + I + + +E + + Sbjct: 614 AVYERATRAVEPAQQYDMFNIYIKRAAE---IYGVTHTRGIYQKAIEV-LSDEHAREMCL 669 Query: 545 EDADSCVAHNALECARAIYAYALQVFPSKK--SVWLRAAYFEKNHGTRESLEALL--QRA 600 AD ++ ARAIY++ Q+ + + W FE HG ++++ +L +R+ Sbjct: 670 RFADMECKLGEIDRARAIYSFCSQICDPRTTGAFWQTWKDFEVRHGNEDTIKEMLRIRRS 729 Query: 601 VAHCPKAEVLWLMGAKSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKL--ESENDEY 658 V +V ++ K ++G S LA + + + A +L E+E D+ Sbjct: 730 VQATYNTQVNFMASQMLK-VSGSATGTVSDLAPGQSGMDDMKLLEQRAEQLAAEAERDQP 788 Query: 659 ERARRLLAKARSSA 672 RA+ + RS A Sbjct: 789 LRAQSKILFVRSDA 802 Score = 38.9 bits (89), Expect = 0.023 Identities = 103/465 (22%), Positives = 178/465 (38%), Gaps = 64/465 (13%) Query: 376 YIRAAELETDIRAKKRVLRKALEHVPNSVRLWKAAVELEEPEDARIM-----LSRAVECC 430 YIR+ E + +R + V + +++ + + EE A M L R E Sbjct: 266 YIRSGHFEKARDVYEEAIRTVMT-VRDFTQVFDSYAQFEESMIAAKMETASELGREEE-- 322 Query: 431 PTSVELWLALARLETYENARKVLNKA---RENIPTDRHIWITAAKLEEA------NGNTQ 481 V+L L LAR E + R +L + R+N P H W L + N T+ Sbjct: 323 -DDVDLELRLARFEQLISRRPLLLNSVLLRQN-PHHVHEWHKRVALHQGRPREIINTYTE 380 Query: 482 MVEKIIDRAITSLRANGVEINREQWIQDAEECDRAGSVATCQAVMRAVIGIGIEE-EDRK 540 V+ + +A G W+ A+ + G + + ++ + ++ +D Sbjct: 381 AVQ-----TVDPFKATGKP--HTLWVAFAKFYEDNGQLDDARVILEKATKVNFKQVDDLA 433 Query: 541 HTWMEDADSCVAHN-------------ALECARAIYAYALQ-----VFPSKKSVWLRAAY 582 W + + + H AL RA Y + V+ S K VW A Sbjct: 434 SVWCQCGELELRHENYDEALRLLRKATALPARRAEYFDGSEPVQNRVYKSLK-VWSMLAD 492 Query: 583 FEKNHGTRESLEALLQRAV---AHCPKAEVLWLMGAKS-KWLAGDVPAARSILALAFQAN 638 E++ GT +S +A+ R + P+ + + M + K+ A ++L Sbjct: 493 LEESLGTFQSTKAVYDRILDLRIATPQIVINYAMFLEEHKYFEESFKAYERGISLFKW-- 550 Query: 639 PNSEEIW---LAAVKLESENDEYERARRLLAKARSSAP---TARVFMKSVKLEWVQDNIR 692 PN +IW L + ERAR L +A P +++ +LE R Sbjct: 551 PNVSDIWSTYLTKFIARYGGRKLERARDLFEQALDGCPPKYAKTLYLLYAQLEEEWGLAR 610 Query: 693 AAQDLCEEALRHYEDFPKLWMMKGQIEEQKEM--MEKAREAYNQGLKKCP--HSTPLWLL 748 A + E A R E + M I+ E+ + R Y + ++ H+ + L Sbjct: 611 HAMAVYERATRAVEPAQQYDMFNIYIKRAAEIYGVTHTRGIYQKAIEVLSDEHAREMCLR 670 Query: 749 LSRLEEKIGQLTRARAILE-KSRLKNPKNPG-LWLESVRLEYRAG 791 + +E K+G++ RARAI S++ +P+ G W E R G Sbjct: 671 FADMECKLGEIDRARAIYSFCSQICDPRTTGAFWQTWKDFEVRHG 715 Score = 34.3 bits (77), Expect = 0.56 Identities = 44/191 (23%), Positives = 83/191 (43%), Gaps = 30/191 (15%) Query: 635 FQANPNSEEIWLAAVKLESENDEYERARRLLAKARSSAPTARVFMKSVKLEWVQDNIRAA 694 F+A +W+A K +N + + AR +L KA +V K V D++ + Sbjct: 388 FKATGKPHTLWVAFAKFYEDNGQLDDARVILEKA------TKVNFKQV------DDLASV 435 Query: 695 QDLCEE-ALRH--YEDFPKLWMMKGQIEEQK-EMMEKAREAYNQGLKKCPHSTPLWLLLS 750 C E LRH Y++ +L + ++ E + + N+ K S +W +L+ Sbjct: 436 WCQCGELELRHENYDEALRLLRKATALPARRAEYFDGSEPVQNRVYK----SLKVWSMLA 491 Query: 751 RLEEKIGQLTRARAILEK---SRLKNPK---NPGLWLESVRLEYRAGLKNIANTLMAKAL 804 LEE +G +A+ ++ R+ P+ N ++LE E++ ++ +L Sbjct: 492 DLEESLGTFQSTKAVYDRILDLRIATPQIVINYAMFLE----EHKYFEESFKAYERGISL 547 Query: 805 QECPNSGILWS 815 + PN +WS Sbjct: 548 FKWPNVSDIWS 558 Score = 32.7 bits (73), Expect = 1.6 Identities = 78/393 (19%), Positives = 140/393 (35%), Gaps = 42/393 (10%) Query: 550 CVAHNALECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRAVAHCPKAE- 608 CV A E + A +WL F + G RA+ P + Sbjct: 86 CVTDPAYEDVNNCHERAFVFMHKMPRLWLDYCQFLMDQGRVTHTRRTFDRALRALPITQH 145 Query: 609 ----VLWLMGAKSKWLAGD-VPAARSILALAFQANPNSEEIWLAAVKLESENDEYERARR 663 L+L +S L V R L L+ P S E ++ +K DE A+R Sbjct: 146 SRIWPLYLRFLRSHPLPETAVRGYRRFLKLS----PESAEEYIEYLKSSDRLDE--AAQR 199 Query: 664 LLAKARSSAPTARVFMKSVKL-----EWVQDNIRAAQDLCEEAL------RHYEDFPKLW 712 L ++ + +L + + N Q L +A+ R + KLW Sbjct: 200 LATVVNDERFVSKAGKSNYQLWHELCDLISQNPDKVQSLNVDAIIRGGLTRFTDQLGKLW 259 Query: 713 MMKGQIEEQKEMMEKAREAYNQGLK---KCPHSTPLWLLLSRLEEKIGQLTRARAILEKS 769 + EKAR+ Y + ++ T ++ ++ EE + A + S Sbjct: 260 CSLADYYIRSGHFEKARDVYEEAIRTVMTVRDFTQVFDSYAQFEESM----IAAKMETAS 315 Query: 770 RLKNPKNPGLWLESVRLEYRAGLKNIANTLMAKALQECPNSGILWSEAIFL-EARPQR-- 826 L + + LE + + L + L++ P+ W + + L + RP+ Sbjct: 316 ELGREEEDDVDLELRLARFEQLISRRPLLLNSVLLRQNPHHVHEWHKRVALHQGRPREII 375 Query: 827 --RTKSVDALK--KCEHDPHVL-LAVAKLFWSQRKITKAREWFHRTVKID----SDLGDA 877 T++V + K PH L +A AK + ++ AR + K++ DL Sbjct: 376 NTYTEAVQTVDPFKATGKPHTLWVAFAKFYEDNGQLDDARVILEKATKVNFKQVDDLASV 435 Query: 878 WAFFYKFELQHGTEEQQEEVRKRCESAEPRHGE 910 W + EL+H ++ + ++ + R E Sbjct: 436 WCQCGELELRHENYDEALRLLRKATALPARRAE 468 >gi|4758472 G protein pathway suppressor 2 [Homo sapiens] Length = 327 Score = 43.1 bits (100), Expect = 0.001 Identities = 33/109 (30%), Positives = 60/109 (55%), Gaps = 6/109 (5%) Query: 108 LDKRMDERRKERREQREKEEIEKYRMERPKIQQQFSDLKRKLAEVTEEE---WLSIPEVG 164 +DK M+++ KE +E+R+K+E+E+ RM + ++Q L+ KL + EE+ +L + +V Sbjct: 36 VDKMMEQKMKEEQERRKKKEMEE-RMSLEETKEQILKLEEKLLALQEEKHQLFLQLKKVL 94 Query: 165 DARNKRQRNPRYEKLTPVPDSFFAKHLQTGENHTSVDPRQTQFGGLNTP 213 KR+R + + LT + + + + L T T + Q GG N P Sbjct: 95 HEEEKRRRKEQSD-LTTLTSAAYQQSL-TVHTGTHLLSMQGSPGGHNRP 141 >gi|21450645 tetratricopeptide repeat domain 16 [Homo sapiens] Length = 873 Score = 42.4 bits (98), Expect = 0.002 Identities = 54/248 (21%), Positives = 100/248 (40%), Gaps = 19/248 (7%) Query: 419 ARIMLSRAVECCPTSVELWLALARLETYENARKVLNKARENIPTDRHIWITAA----KLE 474 AR++L + V + + LA ++A + +N+A EN P D +++ +L+ Sbjct: 240 ARMLLQKMVAQAQQARQDAGILAVQGKLQHALQRINRAIENNPLDPSLFLFRGTMYRRLQ 299 Query: 475 EANGNTQMVEKIIDRAITSLRANGVEINREQWIQD----AEECDRAGSVATCQAVMRAVI 530 E +G + K++D +T + + V + Q + A C R G+ ++ + Sbjct: 300 EFDGAVEDFLKVLDM-VTEDQEDMVRQAQRQLLLTYNDFAVHCYRQGAYQEGVLLLNKAL 358 Query: 531 GIGIEEEDRKHTWMEDADSCVAHNALECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTR 590 +E+ K ++ D L A A Y AL + P + R ++ G Sbjct: 359 R---DEQQEKGLYINRGDCFFQLGNLAFAEADYQQALALSPQDEGANTRMGLLQEKMGFC 415 Query: 591 ESLEALLQRA-------VAHCPKAEVLWLMGAKSKWLAGDVPAARSILALAFQANPNSEE 643 E Q+A + H P+ +L AKS+ L ++ AR +A NP + Sbjct: 416 EQRRKQFQKAENHFSTAIRHNPQKAQYYLYRAKSRQLLQNIFGARQDVATVLLLNPKQPK 475 Query: 644 IWLAAVKL 651 + L L Sbjct: 476 LSLLMTNL 483 >gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapiens] Length = 820 Score = 42.0 bits (97), Expect = 0.003 Identities = 29/86 (33%), Positives = 43/86 (50%), Gaps = 11/86 (12%) Query: 95 EKDDEEADAIYAALDKRMDERRKERREQREKEEIEKYRMERPKIQQQFSDLKRKLAEVTE 154 +K +EEA+A L K E +R Q+E EE ++ E K ++QF DL RK+ E + Sbjct: 151 KKAEEEAEAKPKFLSKAEREAEALKRRQQEVEERQRMLEEERKKRKQFQDLGRKMLEDPQ 210 Query: 155 EEWLSIPEVGDARNKRQRNPRYEKLT 180 E R +R+R R E+ T Sbjct: 211 E-----------RERRERRERMERET 225 >gi|112789538 troponin T3, skeletal, fast isoform 2 [Homo sapiens] Length = 256 Score = 41.6 bits (96), Expect = 0.004 Identities = 28/114 (24%), Positives = 54/114 (47%), Gaps = 4/114 (3%) Query: 37 ARDANDPVDDRHAPPGKRTVGDQMKKNQAADDDDEDLNDTNYD--EFNGYAGSLFSSGPY 94 A + ++ V + P + ++ + + D DD N D E S F + Sbjct: 23 AAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEAR-- 80 Query: 95 EKDDEEADAIYAALDKRMDERRKERREQREKEEIEKYRMERPKIQQQFSDLKRK 148 +K++EE A+ ++KR ER +++R + EKE + R+ K +++ D KR+ Sbjct: 81 KKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRR 134 >gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens] Length = 1036 Score = 40.8 bits (94), Expect = 0.006 Identities = 57/262 (21%), Positives = 96/262 (36%), Gaps = 14/262 (5%) Query: 547 ADSCVAHNALECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRAVAHCPK 606 A + VA +E A Y ALQ P V K G E +A +A+ P Sbjct: 120 AAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPN 179 Query: 607 AEVLWLMGAKSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESENDEYERARRLLA 666 V W G++ A A +PN + ++ + E ++RA Sbjct: 180 FAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYL 239 Query: 667 KARSSAPTARVFMKSVKLEWVQDN-IRAAQDLCEEALRHYEDFPKLWMMKGQIEEQKEMM 725 +A S +P V ++ + + I A D A+ FP + ++K + Sbjct: 240 RALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSV 299 Query: 726 EKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESVR 785 +A + YN L+ CP L+ ++ + G + A + K+ P Sbjct: 300 AEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFP----------- 348 Query: 786 LEYRAGLKNIANTLMAKA-LQE 806 E+ A N+A+ L + LQE Sbjct: 349 -EFAAAHSNLASVLQQQGKLQE 369 Score = 32.0 bits (71), Expect = 2.8 Identities = 37/183 (20%), Positives = 79/183 (43%), Gaps = 21/183 (11%) Query: 303 ETNPHHPPAWIASARLEEVTGKLQVARNLIMKGTEMCPKSEDVWLEAARLQPGDTAKAVV 362 E PH P A+ A + G + A + +CP D A ++ + + Sbjct: 277 ELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIK---REQGNI 333 Query: 363 AQAVRHLPQSVRIYIRAAELETDIRA---KKRVLRKALEHVPNSVRLWKAAVE------- 412 +AVR +++ ++ A +++ + ++ L++AL H ++R+ + Sbjct: 334 EEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGN 393 Query: 413 -LEEPEDARIMLSRAVECCPTSVELWLALARLETYENARKVLNKARENIPTDRHIWITAA 471 L+E +D + A++C ++++ A A + + N + +K NIP + TA Sbjct: 394 TLKEMQD----VQGALQCYTRAIQINPAFA--DAHSNLASI-HKDSGNIPEAIASYRTAL 446 Query: 472 KLE 474 KL+ Sbjct: 447 KLK 449 >gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens] Length = 1046 Score = 40.8 bits (94), Expect = 0.006 Identities = 57/262 (21%), Positives = 96/262 (36%), Gaps = 14/262 (5%) Query: 547 ADSCVAHNALECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRAVAHCPK 606 A + VA +E A Y ALQ P V K G E +A +A+ P Sbjct: 130 AAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPN 189 Query: 607 AEVLWLMGAKSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESENDEYERARRLLA 666 V W G++ A A +PN + ++ + E ++RA Sbjct: 190 FAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYL 249 Query: 667 KARSSAPTARVFMKSVKLEWVQDN-IRAAQDLCEEALRHYEDFPKLWMMKGQIEEQKEMM 725 +A S +P V ++ + + I A D A+ FP + ++K + Sbjct: 250 RALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSV 309 Query: 726 EKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESVR 785 +A + YN L+ CP L+ ++ + G + A + K+ P Sbjct: 310 AEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFP----------- 358 Query: 786 LEYRAGLKNIANTLMAKA-LQE 806 E+ A N+A+ L + LQE Sbjct: 359 -EFAAAHSNLASVLQQQGKLQE 379 Score = 32.0 bits (71), Expect = 2.8 Identities = 37/183 (20%), Positives = 79/183 (43%), Gaps = 21/183 (11%) Query: 303 ETNPHHPPAWIASARLEEVTGKLQVARNLIMKGTEMCPKSEDVWLEAARLQPGDTAKAVV 362 E PH P A+ A + G + A + +CP D A ++ + + Sbjct: 287 ELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIK---REQGNI 343 Query: 363 AQAVRHLPQSVRIYIRAAELETDIRA---KKRVLRKALEHVPNSVRLWKAAVE------- 412 +AVR +++ ++ A +++ + ++ L++AL H ++R+ + Sbjct: 344 EEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGN 403 Query: 413 -LEEPEDARIMLSRAVECCPTSVELWLALARLETYENARKVLNKARENIPTDRHIWITAA 471 L+E +D + A++C ++++ A A + + N + +K NIP + TA Sbjct: 404 TLKEMQD----VQGALQCYTRAIQINPAFA--DAHSNLASI-HKDSGNIPEAIASYRTAL 456 Query: 472 KLE 474 KL+ Sbjct: 457 KLK 459 >gi|148839339 nexilin (F actin binding protein) [Homo sapiens] Length = 675 Score = 40.8 bits (94), Expect = 0.006 Identities = 30/154 (19%), Positives = 64/154 (41%), Gaps = 4/154 (2%) Query: 12 PAPLGYVPGLGRGATGFTTRSDIGPARDANDPVDDRHAPPGKRTVGDQMKKNQAADDDDE 71 P P YVP LG+G + + A + + R + K+ +Q + + + + Sbjct: 17 PVPKTYVPKLGKG----DVKDKFEAMQRAREERNQRRSRDEKQRRKEQYIREREWNRRKQ 72 Query: 72 DLNDTNYDEFNGYAGSLFSSGPYEKDDEEADAIYAALDKRMDERRKERREQREKEEIEKY 131 ++ + + S K +A ++K+ E +++R E+ K IE+ Sbjct: 73 EIKEMLASDDEEDVSSKVEKAYVPKLTGTVKGRFAEMEKQRQEEQRKRTEEERKRRIEQD 132 Query: 132 RMERPKIQQQFSDLKRKLAEVTEEEWLSIPEVGD 165 +E+ KIQ++ + ++ ++ S E GD Sbjct: 133 MLEKRKIQRELAKRAEQIEDINNTGTESASEEGD 166 Score = 33.1 bits (74), Expect = 1.2 Identities = 29/136 (21%), Positives = 60/136 (44%), Gaps = 15/136 (11%) Query: 59 QMKKNQAADDDDEDLNDTNYDEFNGYAGSLFSSGPYEKDDEEADAIYAALDKRMDERRKE 118 + ++N DDD ++ T EF + G E + EE +KR E ++ Sbjct: 346 EARRNMVVDDDSPEMYKTISQEF-------LTPGKLEINFEELLKQKMEEEKRRTEEERK 398 Query: 119 RREQREKEEIEKYRMERPKIQQQFS--DLKRKLAEVTEEEWLSIPEVGDARNKRQRNPRY 176 + + EK+E E+ R E + +++ L R+ EE + + G + K ++ ++ Sbjct: 399 HKLEMEKQEFEQLRQEMGEEEEENETFGLSREY-----EELIKLKRSGSIQAKNLKS-KF 452 Query: 177 EKLTPVPDSFFAKHLQ 192 EK+ + + K ++ Sbjct: 453 EKIGQLSEKEIQKKIE 468 >gi|4504487 histidine rich calcium binding protein precursor [Homo sapiens] Length = 699 Score = 40.0 bits (92), Expect = 0.010 Identities = 29/115 (25%), Positives = 58/115 (50%), Gaps = 9/115 (7%) Query: 48 HAPPGKRTVGDQ--MKKNQAADDDDEDLNDTNYDEFN-----GYAGSLFSSGPYEKDDEE 100 H PPG V D+ ++K+ + ++ +++ + +++E + G G+ G +++DEE Sbjct: 463 HHPPGHTVVKDRSHLRKDDSEEEKEKEEDPGSHEEDDESSEQGEKGT--HHGSRDQEDEE 520 Query: 101 ADAIYAALDKRMDERRKERREQREKEEIEKYRMERPKIQQQFSDLKRKLAEVTEE 155 + L +E +E +E+ E+EE E+ R ER ++ S + E EE Sbjct: 521 DEEEGHGLSLNQEEEEEEDKEEEEEEEDEERREERAEVGAPLSPDHSEEEEEEEE 575 >gi|5803203 troponin T3, skeletal, fast isoform 1 [Homo sapiens] Length = 258 Score = 39.3 bits (90), Expect = 0.017 Identities = 27/106 (25%), Positives = 49/106 (46%), Gaps = 4/106 (3%) Query: 45 DDRHAPPGKRTVGDQMKKNQAADDDDEDLNDTNYD--EFNGYAGSLFSSGPYEKDDEEAD 102 D P + ++ + + D DD N D E S F + +K++EE Sbjct: 33 DAEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEAR--KKEEEELV 90 Query: 103 AIYAALDKRMDERRKERREQREKEEIEKYRMERPKIQQQFSDLKRK 148 A+ ++KR ER +++R + EKE + R+ K +++ D KR+ Sbjct: 91 ALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRR 136 >gi|24307965 UBX domain containing 2 [Homo sapiens] Length = 508 Score = 39.3 bits (90), Expect = 0.017 Identities = 24/81 (29%), Positives = 44/81 (54%), Gaps = 7/81 (8%) Query: 95 EKDDEEADAIYAALDKRMDERRKERREQREKEEIEKYRMERPKIQQQFSDLKRKLAEVTE 154 ++ E+ + L K+++ERR+E+R++ E+ EI+K +ER K ++ D KRK E Sbjct: 189 QRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKK-EIERRKTGKEMLDYKRKQEEELT 247 Query: 155 EEWLSIPEVGDARNKRQRNPR 175 + L + RN+ + R Sbjct: 248 KRML------EERNREKAEDR 262 >gi|7110679 tetratricopeptide repeat domain 33 [Homo sapiens] Length = 262 Score = 39.3 bits (90), Expect = 0.017 Identities = 37/148 (25%), Positives = 59/148 (39%), Gaps = 17/148 (11%) Query: 640 NSEEIWLAAVKLESE---NDEYERARRLLAKARSSAPTARVFMKSVKLEWVQDNIRAAQD 696 N E WL A+K E E++++L + S A R R A Sbjct: 35 NDEGNWLHAIKRRKEILLEGCAEKSKQLKDEGASLAENKRY--------------REAIQ 80 Query: 697 LCEEALRHYEDFPKLWMMKGQIEEQKEMMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKI 756 +EAL+ + L+ MK Q+ M A A +++ PHS W L R + + Sbjct: 81 KWDEALQLTPNDATLYEMKSQVLMSLHEMFPAVHAAEMAVQQNPHSWESWQTLGRAQLGL 140 Query: 757 GQLTRARAILEKSRLKNPKNPGLWLESV 784 G++ A + + P NP +W E + Sbjct: 141 GEIILAIRSFQVALHIYPMNPEIWKEDL 168 >gi|56549694 enabled homolog isoform a [Homo sapiens] Length = 591 Score = 38.9 bits (89), Expect = 0.023 Identities = 18/69 (26%), Positives = 43/69 (62%) Query: 110 KRMDERRKERREQREKEEIEKYRMERPKIQQQFSDLKRKLAEVTEEEWLSIPEVGDARNK 169 + ++ +R++ +EQ+ ++E+E+ R+ER +++++ + +R E E E L ++ R + Sbjct: 138 EELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQEQLERERQE 197 Query: 170 RQRNPRYEK 178 R+R R E+ Sbjct: 198 RERQERLER 206 Score = 37.0 bits (84), Expect = 0.087 Identities = 20/71 (28%), Positives = 41/71 (57%), Gaps = 2/71 (2%) Query: 108 LDKRMDERRKERREQREKEEIEKYRMERPKIQQQFSDLKRKLAEVTEEEWLSIPEVGDAR 167 L++ ER + RE+ E+E +E+ R+ER +++Q+ L+R+ E +E L E + + Sbjct: 156 LERERLERERMERERLERERLERERLERERLEQE--QLERERQERERQERLERQERLERQ 213 Query: 168 NKRQRNPRYEK 178 + +R R ++ Sbjct: 214 ERLERQERLDR 224 Score = 33.1 bits (74), Expect = 1.2 Identities = 18/66 (27%), Positives = 37/66 (56%) Query: 114 ERRKERREQREKEEIEKYRMERPKIQQQFSDLKRKLAEVTEEEWLSIPEVGDARNKRQRN 173 ER + RE+ E+E +E+ R+ER +++++ + ++ E E E E + +++R Sbjct: 157 ERERLERERMERERLERERLERERLERERLEQEQLERERQERERQERLERQERLERQERL 216 Query: 174 PRYEKL 179 R E+L Sbjct: 217 ERQERL 222 Score = 32.7 bits (73), Expect = 1.6 Identities = 22/75 (29%), Positives = 40/75 (53%), Gaps = 5/75 (6%) Query: 110 KRMDERRKER----REQREKEEIEKYRMERPKIQQQFSDLKRKLAEVTEEEWLSIPEVGD 165 +RM+ R ER RE+ E+E +E+ ++ER + +++ + + + +E L E D Sbjct: 164 ERMERERLERERLERERLERERLEQEQLERERQERERQERLERQERLERQERLERQERLD 223 Query: 166 -ARNKRQRNPRYEKL 179 R +RQ R E+L Sbjct: 224 RERQERQERERLERL 238 Score = 31.2 bits (69), Expect = 4.7 Identities = 17/50 (34%), Positives = 29/50 (58%), Gaps = 4/50 (8%) Query: 110 KRMDERRKERREQREKEEIEKYRMERPKIQQQFSDLKRKLAEVTEEEWLS 159 +R+D R+ER+E+ E +E+ R ER + +Q L+R+ E E +S Sbjct: 220 ERLDRERQERQERERLERLERERQERERQEQ----LEREQLEWERERRIS 265 >gi|39930375 enabled homolog isoform b [Homo sapiens] Length = 570 Score = 38.9 bits (89), Expect = 0.023 Identities = 18/69 (26%), Positives = 43/69 (62%) Query: 110 KRMDERRKERREQREKEEIEKYRMERPKIQQQFSDLKRKLAEVTEEEWLSIPEVGDARNK 169 + ++ +R++ +EQ+ ++E+E+ R+ER +++++ + +R E E E L ++ R + Sbjct: 138 EELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQEQLERERQE 197 Query: 170 RQRNPRYEK 178 R+R R E+ Sbjct: 198 RERQERLER 206 Score = 37.0 bits (84), Expect = 0.087 Identities = 20/71 (28%), Positives = 41/71 (57%), Gaps = 2/71 (2%) Query: 108 LDKRMDERRKERREQREKEEIEKYRMERPKIQQQFSDLKRKLAEVTEEEWLSIPEVGDAR 167 L++ ER + RE+ E+E +E+ R+ER +++Q+ L+R+ E +E L E + + Sbjct: 156 LERERLERERMERERLERERLERERLERERLEQE--QLERERQERERQERLERQERLERQ 213 Query: 168 NKRQRNPRYEK 178 + +R R ++ Sbjct: 214 ERLERQERLDR 224 Score = 33.1 bits (74), Expect = 1.2 Identities = 18/66 (27%), Positives = 37/66 (56%) Query: 114 ERRKERREQREKEEIEKYRMERPKIQQQFSDLKRKLAEVTEEEWLSIPEVGDARNKRQRN 173 ER + RE+ E+E +E+ R+ER +++++ + ++ E E E E + +++R Sbjct: 157 ERERLERERMERERLERERLERERLERERLEQEQLERERQERERQERLERQERLERQERL 216 Query: 174 PRYEKL 179 R E+L Sbjct: 217 ERQERL 222 Score = 32.7 bits (73), Expect = 1.6 Identities = 22/75 (29%), Positives = 40/75 (53%), Gaps = 5/75 (6%) Query: 110 KRMDERRKER----REQREKEEIEKYRMERPKIQQQFSDLKRKLAEVTEEEWLSIPEVGD 165 +RM+ R ER RE+ E+E +E+ ++ER + +++ + + + +E L E D Sbjct: 164 ERMERERLERERLERERLERERLEQEQLERERQERERQERLERQERLERQERLERQERLD 223 Query: 166 -ARNKRQRNPRYEKL 179 R +RQ R E+L Sbjct: 224 RERQERQERERLERL 238 Score = 31.2 bits (69), Expect = 4.7 Identities = 17/50 (34%), Positives = 29/50 (58%), Gaps = 4/50 (8%) Query: 110 KRMDERRKERREQREKEEIEKYRMERPKIQQQFSDLKRKLAEVTEEEWLS 159 +R+D R+ER+E+ E +E+ R ER + +Q L+R+ E E +S Sbjct: 220 ERLDRERQERQERERLERLERERQERERQEQ----LEREQLEWERERRIS 265 >gi|116812573 CWC15 homolog [Homo sapiens] Length = 229 Score = 38.9 bits (89), Expect = 0.023 Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 20/98 (20%) Query: 46 DRHAPPGKRTVGDQMKKNQAAD-------DDDEDLNDTNYDEFNGYAGSLFSSGPYEKDD 98 +R P + T + K D D D+ L D ++F E DD Sbjct: 75 NRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEE-----------ESDD 123 Query: 99 EEADAIYAALDKRMDERRKE--RREQREKEEIEKYRME 134 ++ A+ A L+K ER +E R+EQ +K E E+ RME Sbjct: 124 DDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRME 161 >gi|224809432 transmembrane and tetratricopeptide repeat containing 3 [Homo sapiens] Length = 914 Score = 38.9 bits (89), Expect = 0.023 Identities = 34/190 (17%), Positives = 75/190 (39%), Gaps = 27/190 (14%) Query: 688 QDNIRAAQDLCEEALRHYEDFPKLWMMKGQIEEQKEMMEKAREAYNQGLKKCPHSTPLWL 747 + + A L +A+ DF + ++ +G++ + KA+EAY + L+ ++ LW Sbjct: 542 ESRLEEADQLYRQAISMRPDFKQAYISRGELLLKMNKPLKAKEAYLKALELDRNNADLWY 601 Query: 748 LLSRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESVRLEYRAGLKNIANTLMAKALQEC 807 L+ + ++ + A ++ NPK+ Sbjct: 602 NLAIVHIELKEPNEALKNFNRALELNPKHKLALF-------------------------- 635 Query: 808 PNSGILWSEAIFLEARPQRRTKSVDALKKCEHDPHVLLAVAKLFWSQRKITKAREWFHRT 867 NS I+ E+ ++ RP+ R + + + + D + + L +K +A W + Sbjct: 636 -NSAIVMQESGEVKLRPEARKRLLSYINEEPLDANGYFNLGMLAMDDKKDNEAEIWMKKA 694 Query: 868 VKIDSDLGDA 877 +K+ +D A Sbjct: 695 IKLQADFRSA 704 Score = 32.0 bits (71), Expect = 2.8 Identities = 27/84 (32%), Positives = 40/84 (47%), Gaps = 9/84 (10%) Query: 356 DTAKAVVAQAVRHLPQSVRIYIRAAEL----ETDIRAKKRVLRKALEHVPNSVRLWK--- 408 + A + QA+ P + YI EL ++AK+ L KALE N+ LW Sbjct: 546 EEADQLYRQAISMRPDFKQAYISRGELLLKMNKPLKAKEAYL-KALELDRNNADLWYNLA 604 Query: 409 -AAVELEEPEDARIMLSRAVECCP 431 +EL+EP +A +RA+E P Sbjct: 605 IVHIELKEPNEALKNFNRALELNP 628 >gi|112789536 troponin T3, skeletal, fast isoform 3 [Homo sapiens] Length = 250 Score = 38.5 bits (88), Expect = 0.030 Identities = 26/100 (26%), Positives = 48/100 (48%), Gaps = 4/100 (4%) Query: 51 PGKRTVGDQMKKNQAADDDDEDLNDTNYD--EFNGYAGSLFSSGPYEKDDEEADAIYAAL 108 P + ++ + + D DD N D E S F + +K++EE A+ + Sbjct: 31 PRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEAR--KKEEEELVALKERI 88 Query: 109 DKRMDERRKERREQREKEEIEKYRMERPKIQQQFSDLKRK 148 +KR ER +++R + EKE + R+ K +++ D KR+ Sbjct: 89 EKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRR 128 >gi|112789541 troponin T3, skeletal, fast isoform 4 [Homo sapiens] Length = 250 Score = 38.5 bits (88), Expect = 0.030 Identities = 26/100 (26%), Positives = 48/100 (48%), Gaps = 4/100 (4%) Query: 51 PGKRTVGDQMKKNQAADDDDEDLNDTNYD--EFNGYAGSLFSSGPYEKDDEEADAIYAAL 108 P + ++ + + D DD N D E S F + +K++EE A+ + Sbjct: 31 PRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEAR--KKEEEELVALKERI 88 Query: 109 DKRMDERRKERREQREKEEIEKYRMERPKIQQQFSDLKRK 148 +KR ER +++R + EKE + R+ K +++ D KR+ Sbjct: 89 EKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRR 128 >gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo sapiens] Length = 1939 Score = 37.7 bits (86), Expect = 0.051 Identities = 29/88 (32%), Positives = 48/88 (54%), Gaps = 13/88 (14%) Query: 97 DDEEADAIYAALDKRMDERRKERREQREKEEIEKYRMERPKIQQQFSDLKRKLAEVTEEE 156 +DE+A AI L K++ E + R + +EEIE R R K ++Q SDL R+L E++E Sbjct: 1099 EDEQALAIQ--LQKKIKEL--QARIEELEEEIEAERASRAKAEKQRSDLSRELEEISER- 1153 Query: 157 WLSIPEVGDARN-----KRQRNPRYEKL 179 + E G A + ++R ++K+ Sbjct: 1154 ---LEEAGGATSAQIEMNKKREAEFQKM 1178 >gi|7662078 tetratricopeptide repeat domain 37 [Homo sapiens] Length = 1564 Score = 37.4 bits (85), Expect = 0.066 Identities = 28/99 (28%), Positives = 49/99 (49%), Gaps = 4/99 (4%) Query: 363 AQAVRHLPQSVRIYIRAAELETDIRAKKRVLRKALEHVPNSVRLWKAAVELEEPEDARIM 422 ++ V+ +S R IR E + ++ K VL++ + V + AA ELE+P+ A+ Sbjct: 3 SKEVKTALKSARDAIRNKEYKEALKHCKTVLKQEKNNYNAWVFIGVAAAELEQPDQAQSA 62 Query: 423 LSRAVECCPTSVELWLALARLETYENARKVLNKARENIP 461 +A E P + W LA L YE + A++++P Sbjct: 63 YKKAAELEPDQLLAWQGLANL--YEKYNHI--NAKDDLP 97 >gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo sapiens] Length = 1937 Score = 37.4 bits (85), Expect = 0.066 Identities = 27/86 (31%), Positives = 44/86 (51%), Gaps = 11/86 (12%) Query: 99 EEADAIYAALDKRMDERRKERREQREKEEIEKYRMERPKIQQQFSDLKRKLAEVTEEEWL 158 E+ A+ L K++ E + R + EEIE R R K ++Q SDL R+L E++E Sbjct: 1098 EDEQAVEIQLQKKIKEL--QARIEELGEEIEAERASRAKAEKQRSDLSRELEEISER--- 1152 Query: 159 SIPEVGDARN-----KRQRNPRYEKL 179 + E G A + ++R ++KL Sbjct: 1153 -LEEAGGATSAQVELNKKREAEFQKL 1177 >gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sapiens] Length = 2603 Score = 37.4 bits (85), Expect = 0.066 Identities = 35/107 (32%), Positives = 48/107 (44%), Gaps = 5/107 (4%) Query: 58 DQMKKNQAADDDDEDLNDTNYDEFNGYAGSLFSSGPYEKDDEEAD--AIYAALDKRMDER 115 + +KK + D E N A L EK EE+ A+ A +KR ++R Sbjct: 1429 EMLKKCHLCMESIVQAKDRQAAEANKNASILLEELDLEKLREESRRLALAAKREKRKEKR 1488 Query: 116 RKERREQREK-EEIEKYRMERPKIQQQFSDLKRKLAEVTEEEWLSIP 161 RK++ EQR K EEIE E + Q + K KL E E L+ P Sbjct: 1489 RKKKEEQRRKLEEIEAKNKE--NFELQAAQEKEKLKVEDEPEVLTEP 1533 >gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo sapiens] Length = 2352 Score = 37.4 bits (85), Expect = 0.066 Identities = 35/107 (32%), Positives = 48/107 (44%), Gaps = 5/107 (4%) Query: 58 DQMKKNQAADDDDEDLNDTNYDEFNGYAGSLFSSGPYEKDDEEAD--AIYAALDKRMDER 115 + +KK + D E N A L EK EE+ A+ A +KR ++R Sbjct: 1178 EMLKKCHLCMESIVQAKDRQAAEANKNASILLEELDLEKLREESRRLALAAKREKRKEKR 1237 Query: 116 RKERREQREK-EEIEKYRMERPKIQQQFSDLKRKLAEVTEEEWLSIP 161 RK++ EQR K EEIE E + Q + K KL E E L+ P Sbjct: 1238 RKKKEEQRRKLEEIEAKNKE--NFELQAAQEKEKLKVEDEPEVLTEP 1282 >gi|4505257 moesin [Homo sapiens] Length = 577 Score = 37.0 bits (84), Expect = 0.087 Identities = 22/88 (25%), Positives = 41/88 (46%), Gaps = 4/88 (4%) Query: 95 EKDDEEADAIYAALDKRMDERRKERREQREKEEIEKYRMERPKIQQQFSDLKRKLAEVTE 154 E+D+++ + A+ D R D K+R E+ E EK ++Q+ L +LA + Sbjct: 479 EQDEQDENGAEASADLRADAMAKDRSEEERTTEAEK----NERVQKHLKALTSELANARD 534 Query: 155 EEWLSIPEVGDARNKRQRNPRYEKLTPV 182 E + ++ A N R +Y+ L + Sbjct: 535 ESKKTANDMIHAENMRLGRDKYKTLRQI 562 Score = 30.8 bits (68), Expect = 6.2 Identities = 18/66 (27%), Positives = 36/66 (54%), Gaps = 2/66 (3%) Query: 108 LDKRMDERRKERRE--QREKEEIEKYRMERPKIQQQFSDLKRKLAEVTEEEWLSIPEVGD 165 +++ M E K++RE ++EKE+IE+ + E + +Q + +K + EE+ E+ Sbjct: 318 MERAMLENEKKKREMAEKEKEKIEREKEELMERLKQIEEQTKKAQQELEEQTRRALELEQ 377 Query: 166 ARNKRQ 171 R + Q Sbjct: 378 ERKRAQ 383 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.131 0.393 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 36,829,022 Number of Sequences: 37866 Number of extensions: 1686660 Number of successful extensions: 10753 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 98 Number of HSP's successfully gapped in prelim test: 201 Number of HSP's that attempted gapping in prelim test: 8596 Number of HSP's gapped (non-prelim): 1779 length of query: 941 length of database: 18,247,518 effective HSP length: 112 effective length of query: 829 effective length of database: 14,006,526 effective search space: 11611410054 effective search space used: 11611410054 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.