Guide to the Human Genome
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Search of human proteins with 40556361

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|40556361 WD repeat domain 93 [Homo sapiens]
         (686 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|40556361 WD repeat domain 93 [Homo sapiens]                       1417   0.0  
gi|194294523 intersectin 2 isoform 3 [Homo sapiens]                    36   0.10 
gi|194294521 intersectin 2 isoform 1 [Homo sapiens]                    36   0.10 
gi|194294525 intersectin 2 isoform 2 [Homo sapiens]                    36   0.10 
gi|167003762 hypothetical protein LOC645090 [Homo sapiens]             32   2.0  
gi|45238854 basic leucine zipper transcription factor, ATF-like ...    32   2.0  
gi|228008407 serine active site containing 1 [Homo sapiens]            31   3.3  
gi|215820619 zinc finger protein 646 [Homo sapiens]                    31   3.3  
gi|33946327 nucleoporin 214kDa [Homo sapiens]                          31   4.4  
gi|30795121 F-box and WD repeat domain containing 8 isoform 2 [H...    31   4.4  
gi|30795123 F-box and WD repeat domain containing 8 isoform 1 [H...    31   4.4  
gi|23199987 WD repeat domain 5B [Homo sapiens]                         30   7.4  
gi|4505293 MYB-related protein B [Homo sapiens]                        30   9.7  
gi|47132534 STAM binding protein [Homo sapiens]                        30   9.7  
gi|42519912 STAM binding protein [Homo sapiens]                        30   9.7  
gi|5453545 STAM binding protein [Homo sapiens]                         30   9.7  
gi|115511012 coiled-coil domain containing 136 [Homo sapiens]          30   9.7  

>gi|40556361 WD repeat domain 93 [Homo sapiens]
          Length = 686

 Score = 1417 bits (3668), Expect = 0.0
 Identities = 686/686 (100%), Positives = 686/686 (100%)

Query: 1   MSFPRGSQTQKIKHPIGTRKGPLEVPPPTEKDWPKDDEQDHVLVDPDEELDSLPQPYRMI 60
           MSFPRGSQTQKIKHPIGTRKGPLEVPPPTEKDWPKDDEQDHVLVDPDEELDSLPQPYRMI
Sbjct: 1   MSFPRGSQTQKIKHPIGTRKGPLEVPPPTEKDWPKDDEQDHVLVDPDEELDSLPQPYRMI 60

Query: 61  NKLVNLLFDQSWEIIEERNALREAESSQIQPTVYPPLGEIQLNKMPNCMAVSQDYVFIGG 120
           NKLVNLLFDQSWEIIEERNALREAESSQIQPTVYPPLGEIQLNKMPNCMAVSQDYVFIGG
Sbjct: 61  NKLVNLLFDQSWEIIEERNALREAESSQIQPTVYPPLGEIQLNKMPNCMAVSQDYVFIGG 120

Query: 121 AKGFSIYNLYSAKQIYAWEKLKVDVTSIWATDLGNEILIAPVDEMGIIRLFYFYKEGLYL 180
           AKGFSIYNLYSAKQIYAWEKLKVDVTSIWATDLGNEILIAPVDEMGIIRLFYFYKEGLYL
Sbjct: 121 AKGFSIYNLYSAKQIYAWEKLKVDVTSIWATDLGNEILIAPVDEMGIIRLFYFYKEGLYL 180

Query: 181 VKAINEVDDTSKQTTCIKMEISQGGDFAAFLLQGAGDIWLDVYKLPKETWLKKLEHPQLT 240
           VKAINEVDDTSKQTTCIKMEISQGGDFAAFLLQGAGDIWLDVYKLPKETWLKKLEHPQLT
Sbjct: 181 VKAINEVDDTSKQTTCIKMEISQGGDFAAFLLQGAGDIWLDVYKLPKETWLKKLEHPQLT 240

Query: 241 SNPKKKVRQPQLNSLGPISADPLEMDANVSFKGDIKLSLPVYIMKIKPPKPVTGTTFKSP 300
           SNPKKKVRQPQLNSLGPISADPLEMDANVSFKGDIKLSLPVYIMKIKPPKPVTGTTFKSP
Sbjct: 241 SNPKKKVRQPQLNSLGPISADPLEMDANVSFKGDIKLSLPVYIMKIKPPKPVTGTTFKSP 300

Query: 301 LEVFAKIKDCYGLGSGQNHFIKDSQWEQQAEIFNASYKKYLDREWEEEPLSTATFYFLLP 360
           LEVFAKIKDCYGLGSGQNHFIKDSQWEQQAEIFNASYKKYLDREWEEEPLSTATFYFLLP
Sbjct: 301 LEVFAKIKDCYGLGSGQNHFIKDSQWEQQAEIFNASYKKYLDREWEEEPLSTATFYFLLP 360

Query: 361 SCLFAMPPEVKGPSGMACVLGIHWTRSHNFFLYSLNRTLKDKADPEGVWPCAAPIAVSQL 420
           SCLFAMPPEVKGPSGMACVLGIHWTRSHNFFLYSLNRTLKDKADPEGVWPCAAPIAVSQL
Sbjct: 361 SCLFAMPPEVKGPSGMACVLGIHWTRSHNFFLYSLNRTLKDKADPEGVWPCAAPIAVSQL 420

Query: 421 SCSSSYLVLACEDGVLTLWDLAKGFPLGVAALPQGCFCQSIHFLKYFSVHKGQNMYPEGQ 480
           SCSSSYLVLACEDGVLTLWDLAKGFPLGVAALPQGCFCQSIHFLKYFSVHKGQNMYPEGQ
Sbjct: 421 SCSSSYLVLACEDGVLTLWDLAKGFPLGVAALPQGCFCQSIHFLKYFSVHKGQNMYPEGQ 480

Query: 481 VKSQMKCVVLCTDASLHLVEASGTQGPTISVLVERPVKHLDKTICAVAPVPALPGMVLIF 540
           VKSQMKCVVLCTDASLHLVEASGTQGPTISVLVERPVKHLDKTICAVAPVPALPGMVLIF
Sbjct: 481 VKSQMKCVVLCTDASLHLVEASGTQGPTISVLVERPVKHLDKTICAVAPVPALPGMVLIF 540

Query: 541 SKNGSVCLMDVAKREIICAFAPPGAFPLEVPWKPVFAVSPDHPCFLLRGDYSHETASTDD 600
           SKNGSVCLMDVAKREIICAFAPPGAFPLEVPWKPVFAVSPDHPCFLLRGDYSHETASTDD
Sbjct: 541 SKNGSVCLMDVAKREIICAFAPPGAFPLEVPWKPVFAVSPDHPCFLLRGDYSHETASTDD 600

Query: 601 AGIQYSVFYFNFEACPLLENISKNCTIPQRDLDNMAFPQALPLEKRCERFLQKSYRKLEK 660
           AGIQYSVFYFNFEACPLLENISKNCTIPQRDLDNMAFPQALPLEKRCERFLQKSYRKLEK
Sbjct: 601 AGIQYSVFYFNFEACPLLENISKNCTIPQRDLDNMAFPQALPLEKRCERFLQKSYRKLEK 660

Query: 661 NPEKEEEHWARLQRYSLSLQRENFKK 686
           NPEKEEEHWARLQRYSLSLQRENFKK
Sbjct: 661 NPEKEEEHWARLQRYSLSLQRENFKK 686


>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
          Length = 1670

 Score = 36.2 bits (82), Expect = 0.10
 Identities = 17/46 (36%), Positives = 28/46 (60%), Gaps = 3/46 (6%)

Query: 641 LPLEKRCERFLQKSYRKLEKNPEKEEEHWARLQRYSLSLQRENFKK 686
           + LEKR +  +++  R+ E+  +KE+E W R QR    LQ + +KK
Sbjct: 376 MELEKRRQALMEQQQREAERKAQKEKEEWERKQR---ELQEQEWKK 418


>gi|194294521 intersectin 2 isoform 1 [Homo sapiens]
          Length = 1697

 Score = 36.2 bits (82), Expect = 0.10
 Identities = 17/46 (36%), Positives = 28/46 (60%), Gaps = 3/46 (6%)

Query: 641 LPLEKRCERFLQKSYRKLEKNPEKEEEHWARLQRYSLSLQRENFKK 686
           + LEKR +  +++  R+ E+  +KE+E W R QR    LQ + +KK
Sbjct: 376 MELEKRRQALMEQQQREAERKAQKEKEEWERKQR---ELQEQEWKK 418


>gi|194294525 intersectin 2 isoform 2 [Homo sapiens]
          Length = 1249

 Score = 36.2 bits (82), Expect = 0.10
 Identities = 17/46 (36%), Positives = 28/46 (60%), Gaps = 3/46 (6%)

Query: 641 LPLEKRCERFLQKSYRKLEKNPEKEEEHWARLQRYSLSLQRENFKK 686
           + LEKR +  +++  R+ E+  +KE+E W R QR    LQ + +KK
Sbjct: 376 MELEKRRQALMEQQQREAERKAQKEKEEWERKQR---ELQEQEWKK 418


>gi|167003762 hypothetical protein LOC645090 [Homo sapiens]
          Length = 633

 Score = 32.0 bits (71), Expect = 2.0
 Identities = 21/66 (31%), Positives = 31/66 (46%), Gaps = 3/66 (4%)

Query: 65  NLLFDQSWE-IIEERNALREAESSQIQPTVYPPLGEIQLNKM--PNCMAVSQDYVFIGGA 121
           NL+ D  W+  I E +A R +  S+IQ    PP G I ++ +  P  M + +  V I   
Sbjct: 234 NLVMDHCWDSFIYESSAFRFSSPSEIQGIALPPKGNIDISLLFIPQIMKLHKTMVIIEMT 293

Query: 122 KGFSIY 127
           K    Y
Sbjct: 294 KANGKY 299


>gi|45238854 basic leucine zipper transcription factor, ATF-like 2
           [Homo sapiens]
          Length = 274

 Score = 32.0 bits (71), Expect = 2.0
 Identities = 43/151 (28%), Positives = 59/151 (39%), Gaps = 20/151 (13%)

Query: 434 GVLTLWDLAKGFPLGVAALPQ-GCFCQSIHFLKYFSVHKGQNMYPEGQVKSQMKCVVLCT 492
           G+L  WD A+G  LG     Q GC  Q   F    S +  Q + P G        ++ C 
Sbjct: 95  GLLGCWDQAEGL-LGPGPQGQHGCREQLELFQTPGSCYPAQPLSP-GPQPHDSPSLLQCP 152

Query: 493 DASLHLVEASGTQGPTISVLVERPVKHLDKTICAVAPVPALPGMVLIFSKNGSVCLMDVA 552
             SL L       GP  +V+ E PV+        ++P P L       S  GS   +   
Sbjct: 153 LPSLSL-------GP--AVVAEPPVQ--------LSPSPLLFASHTGSSLQGSSSKLSAL 195

Query: 553 KREIICAFAPPGAFPLEVPWKPVFAVSPDHP 583
           +  +    APP    LE P +     SPD+P
Sbjct: 196 QPSLTAQTAPPQPLELEHPTRGKLGSSPDNP 226


>gi|228008407 serine active site containing 1 [Homo sapiens]
          Length = 654

 Score = 31.2 bits (69), Expect = 3.3
 Identities = 29/116 (25%), Positives = 50/116 (43%), Gaps = 6/116 (5%)

Query: 49  ELDSLPQPYRMINKLVNLLFDQSWEIIEERNALREAESSQIQPTVYPPLGEIQLNK-MPN 107
           E  + P+   +IN    ++F   + +    + L E  S  I+  ++P L   +L+K  P 
Sbjct: 510 EASTKPEMSTVINNTRGIIF---YSVPHHGSRLAEY-SVNIRYLLFPSLEVKELSKDSPA 565

Query: 108 CMAVSQDYVFIGGAKGFSIYNLYSAKQIYAWEKLKVDVTSIWATDLGNEILIAPVD 163
              +  D++     K F + N       Y    +K+ V  + + DLG   LI PVD
Sbjct: 566 LKTLQDDFLEFAKDKNFQVLNFVETLPTYIGSMIKLHVVPVESADLGIGDLI-PVD 620


>gi|215820619 zinc finger protein 646 [Homo sapiens]
          Length = 1832

 Score = 31.2 bits (69), Expect = 3.3
 Identities = 25/82 (30%), Positives = 40/82 (48%), Gaps = 10/82 (12%)

Query: 23  LEVPP-PTEKDWPKDDEQDHVLVDPDEELDSLPQPYRM---INKLVNLLFDQSWEIIEER 78
           +E+PP P E +     +QDHV    +E  D  P   +    I  +  LLF+ +  +  ER
Sbjct: 535 VELPPDPVEAEAAPHTDQDHVCKHEEEATDITPAADKTAAHICSICGLLFEDAESL--ER 592

Query: 79  NALR----EAESSQIQPTVYPP 96
           + L     E E+S+ + T+ PP
Sbjct: 593 HGLTHGAGEKENSRTETTMSPP 614


>gi|33946327 nucleoporin 214kDa [Homo sapiens]
          Length = 2090

 Score = 30.8 bits (68), Expect = 4.4
 Identities = 13/44 (29%), Positives = 21/44 (47%)

Query: 531 PALPGMVLIFSKNGSVCLMDVAKREIICAFAPPGAFPLEVPWKP 574
           P +P MV +   +GS+ ++ V +   +CA  P       V W P
Sbjct: 159 PTVPSMVAVCLADGSIAVLQVTETVKVCATLPSTVAVTSVCWSP 202


>gi|30795121 F-box and WD repeat domain containing 8 isoform 2 [Homo
           sapiens]
          Length = 532

 Score = 30.8 bits (68), Expect = 4.4
 Identities = 18/45 (40%), Positives = 24/45 (53%), Gaps = 5/45 (11%)

Query: 400 KDKADPEGVWPCAAPIAVSQLSCSSSYLVLACEDGVLTLWDLAKG 444
           +D+ D  G+ P      VS +  +SS  V A EDG L +WDL  G
Sbjct: 184 EDEEDEPGMQP-----NVSFVRINSSLAVAAYEDGFLNIWDLRTG 223


>gi|30795123 F-box and WD repeat domain containing 8 isoform 1 [Homo
           sapiens]
          Length = 598

 Score = 30.8 bits (68), Expect = 4.4
 Identities = 18/45 (40%), Positives = 24/45 (53%), Gaps = 5/45 (11%)

Query: 400 KDKADPEGVWPCAAPIAVSQLSCSSSYLVLACEDGVLTLWDLAKG 444
           +D+ D  G+ P      VS +  +SS  V A EDG L +WDL  G
Sbjct: 250 EDEEDEPGMQP-----NVSFVRINSSLAVAAYEDGFLNIWDLRTG 289


>gi|23199987 WD repeat domain 5B [Homo sapiens]
          Length = 330

 Score = 30.0 bits (66), Expect = 7.4
 Identities = 11/31 (35%), Positives = 17/31 (54%)

Query: 414 PIAVSQLSCSSSYLVLACEDGVLTLWDLAKG 444
           P++    +CS S +V    DG+  +WD A G
Sbjct: 169 PVSAVHFNCSGSLIVSGSYDGLCRIWDAASG 199


>gi|4505293 MYB-related protein B [Homo sapiens]
          Length = 700

 Score = 29.6 bits (65), Expect = 9.7
 Identities = 26/99 (26%), Positives = 44/99 (44%), Gaps = 13/99 (13%)

Query: 9   TQKIKHPIGTRKGPLEVPPPTEKDWPKDDEQDHVLVDPDEELDSLPQPYRMINKLVNLLF 68
           T K + PIGT    +  P P E ++PK ++Q+     P+  L     PY+ + +  NLL 
Sbjct: 250 TSKEQEPIGTDLDAVRTPEPLE-EFPKREDQEG--SPPETSL-----PYKWVVEAANLLI 301

Query: 69  DQSWEIIEERNALREAESSQIQPTVYPPLGEIQLNKMPN 107
                 + E   L E++     P  +  L +  L + P+
Sbjct: 302 PAVGSSLSEALDLIESD-----PDAWCDLSKFDLPEEPS 335


>gi|47132534 STAM binding protein [Homo sapiens]
          Length = 424

 Score = 29.6 bits (65), Expect = 9.7
 Identities = 21/95 (22%), Positives = 42/95 (44%), Gaps = 10/95 (10%)

Query: 598 TDDAGIQYSVFYFNFEACPLLENISKN-----CTIPQRD-----LDNMAFPQALPLEKRC 647
           +++  I+++   +N      +E + K+       IP++      L  +AFP+A  L+   
Sbjct: 51  SEEGNIEHAFILYNKYITLFIEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAEL 110

Query: 648 ERFLQKSYRKLEKNPEKEEEHWARLQRYSLSLQRE 682
            +   K Y +  +  +KE E  AR       L++E
Sbjct: 111 LKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKE 145


>gi|42519912 STAM binding protein [Homo sapiens]
          Length = 424

 Score = 29.6 bits (65), Expect = 9.7
 Identities = 21/95 (22%), Positives = 42/95 (44%), Gaps = 10/95 (10%)

Query: 598 TDDAGIQYSVFYFNFEACPLLENISKN-----CTIPQRD-----LDNMAFPQALPLEKRC 647
           +++  I+++   +N      +E + K+       IP++      L  +AFP+A  L+   
Sbjct: 51  SEEGNIEHAFILYNKYITLFIEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAEL 110

Query: 648 ERFLQKSYRKLEKNPEKEEEHWARLQRYSLSLQRE 682
            +   K Y +  +  +KE E  AR       L++E
Sbjct: 111 LKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKE 145


>gi|5453545 STAM binding protein [Homo sapiens]
          Length = 424

 Score = 29.6 bits (65), Expect = 9.7
 Identities = 21/95 (22%), Positives = 42/95 (44%), Gaps = 10/95 (10%)

Query: 598 TDDAGIQYSVFYFNFEACPLLENISKN-----CTIPQRD-----LDNMAFPQALPLEKRC 647
           +++  I+++   +N      +E + K+       IP++      L  +AFP+A  L+   
Sbjct: 51  SEEGNIEHAFILYNKYITLFIEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAEL 110

Query: 648 ERFLQKSYRKLEKNPEKEEEHWARLQRYSLSLQRE 682
            +   K Y +  +  +KE E  AR       L++E
Sbjct: 111 LKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKE 145


>gi|115511012 coiled-coil domain containing 136 [Homo sapiens]
          Length = 1154

 Score = 29.6 bits (65), Expect = 9.7
 Identities = 21/68 (30%), Positives = 29/68 (42%), Gaps = 15/68 (22%)

Query: 35   KDDEQDHVLVDPDEELDSLPQPYRMINKLVNLLFDQSWEIIEERNALREAESSQIQPTVY 94
            +D E++    D +EE D                 D S E  EE N LR +ES +  PT  
Sbjct: 1083 EDKEEEEKEEDSEEEEDDA---------------DSSLESPEENNPLRLSESKKSSPTPN 1127

Query: 95   PPLGEIQL 102
            PP+  + L
Sbjct: 1128 PPIFSLPL 1135


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.137    0.425 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,815,106
Number of Sequences: 37866
Number of extensions: 1463047
Number of successful extensions: 3853
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 3843
Number of HSP's gapped (non-prelim): 22
length of query: 686
length of database: 18,247,518
effective HSP length: 109
effective length of query: 577
effective length of database: 14,120,124
effective search space: 8147311548
effective search space used: 8147311548
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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