Guide to the Human Genome
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Search of human proteins with 40288203

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|40288203 hypothetical protein LOC219287 isoform 1 [Homo
sapiens]
         (671 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|40288203 hypothetical protein LOC219287 isoform 1 [Homo sapiens]  1361   0.0  
gi|40288199 hypothetical protein LOC219287 isoform 2 [Homo sapiens]   757   0.0  
gi|124244056 family with sequence similarity 123B [Homo sapiens]      209   9e-54
gi|157427665 hypothetical protein LOC205147 [Homo sapiens]            112   8e-25
gi|157427663 hypothetical protein LOC205147 [Homo sapiens]            112   8e-25
gi|157427661 hypothetical protein LOC205147 [Homo sapiens]            112   8e-25
gi|157427667 hypothetical protein LOC205147 [Homo sapiens]            112   8e-25
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    56   1e-07
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    56   1e-07
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      54   6e-07
gi|27894378 chloride intracellular channel 6 [Homo sapiens]            53   8e-07
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ...    53   1e-06
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      52   2e-06
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]          52   2e-06
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...    50   5e-06
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...    50   5e-06
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...    50   5e-06
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     50   5e-06
gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]            49   2e-05
gi|182507165 thymus expressed gene 3-like [Homo sapiens]               48   3e-05
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]       48   3e-05
gi|59806361 hypothetical protein LOC387104 [Homo sapiens]              48   3e-05
gi|163965366 nascent polypeptide-associated complex alpha subuni...    48   3e-05
gi|148833506 obscurin, cytoskeletal calmodulin and titin-interac...    47   4e-05
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]                47   4e-05
gi|117938759 GNAS complex locus XLas [Homo sapiens]                    47   6e-05
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]       46   1e-04
gi|169204930 PREDICTED: hypothetical protein [Homo sapiens]            46   1e-04
gi|239750393 PREDICTED: hypothetical protein [Homo sapiens]            46   1e-04
gi|239744694 PREDICTED: hypothetical protein [Homo sapiens]            46   1e-04

>gi|40288203 hypothetical protein LOC219287 isoform 1 [Homo sapiens]
          Length = 671

 Score = 1361 bits (3522), Expect = 0.0
 Identities = 671/671 (100%), Positives = 671/671 (100%)

Query: 1   METSRSRGGGGAVSERGGAGASVGVCRRKAEAGAGTGTLAADMDLHCDCAAETPAAEPPS 60
           METSRSRGGGGAVSERGGAGASVGVCRRKAEAGAGTGTLAADMDLHCDCAAETPAAEPPS
Sbjct: 1   METSRSRGGGGAVSERGGAGASVGVCRRKAEAGAGTGTLAADMDLHCDCAAETPAAEPPS 60

Query: 61  GKINKAAFKLFKKRKSGGTMPSIFGVKNKGDGKSSGPTGLVRSRTHDGLAEVLVLESGRK 120
           GKINKAAFKLFKKRKSGGTMPSIFGVKNKGDGKSSGPTGLVRSRTHDGLAEVLVLESGRK
Sbjct: 61  GKINKAAFKLFKKRKSGGTMPSIFGVKNKGDGKSSGPTGLVRSRTHDGLAEVLVLESGRK 120

Query: 121 EEPRGGGDSGGGGGGRPNPGPPRAAGPGGGSLASSSVAKSHSFFSLLKKNGRSENGKGEP 180
           EEPRGGGDSGGGGGGRPNPGPPRAAGPGGGSLASSSVAKSHSFFSLLKKNGRSENGKGEP
Sbjct: 121 EEPRGGGDSGGGGGGRPNPGPPRAAGPGGGSLASSSVAKSHSFFSLLKKNGRSENGKGEP 180

Query: 181 VDASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEGRAPGGGLILPGSLTASLECVKEE 240
           VDASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEGRAPGGGLILPGSLTASLECVKEE
Sbjct: 181 VDASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEGRAPGGGLILPGSLTASLECVKEE 240

Query: 241 TPRAAREPEEPSQDAPRDPAGEPAGGEEVPAPADRAPARSCREAEGLAHPGDTGARGEDA 300
           TPRAAREPEEPSQDAPRDPAGEPAGGEEVPAPADRAPARSCREAEGLAHPGDTGARGEDA
Sbjct: 241 TPRAAREPEEPSQDAPRDPAGEPAGGEEVPAPADRAPARSCREAEGLAHPGDTGARGEDA 300

Query: 301 AGHRRAEPGPGEVRTAEDASRTGAVPVKTVPLVDSEGGSGRAPAAPDPASVDPPSDPSAD 360
           AGHRRAEPGPGEVRTAEDASRTGAVPVKTVPLVDSEGGSGRAPAAPDPASVDPPSDPSAD
Sbjct: 301 AGHRRAEPGPGEVRTAEDASRTGAVPVKTVPLVDSEGGSGRAPAAPDPASVDPPSDPSAD 360

Query: 361 RICLMFSDVTSLKSFDSLTGCGDIIADQEEEAGPSCDKHVPGPGKPALSKKNPGVVAYQG 420
           RICLMFSDVTSLKSFDSLTGCGDIIADQEEEAGPSCDKHVPGPGKPALSKKNPGVVAYQG
Sbjct: 361 RICLMFSDVTSLKSFDSLTGCGDIIADQEEEAGPSCDKHVPGPGKPALSKKNPGVVAYQG 420

Query: 421 GGEEMASPDEVDDTYLQEFWDMLSQTEEQGPEPQEGAAKVAAALETKVVPETPKDTRCVE 480
           GGEEMASPDEVDDTYLQEFWDMLSQTEEQGPEPQEGAAKVAAALETKVVPETPKDTRCVE
Sbjct: 421 GGEEMASPDEVDDTYLQEFWDMLSQTEEQGPEPQEGAAKVAAALETKVVPETPKDTRCVE 480

Query: 481 AAKDASSVKRRRLNRIPIEPHPKEEPKHPEKEQQEGVPNSDEGYWDSTTPGPEEDSSSSG 540
           AAKDASSVKRRRLNRIPIEPHPKEEPKHPEKEQQEGVPNSDEGYWDSTTPGPEEDSSSSG
Sbjct: 481 AAKDASSVKRRRLNRIPIEPHPKEEPKHPEKEQQEGVPNSDEGYWDSTTPGPEEDSSSSG 540

Query: 541 KKAGIPRDSYSGDALYDLYADPDGSPATLPGGKDNEETSSLSRLKPVSPGTITCPLRTPG 600
           KKAGIPRDSYSGDALYDLYADPDGSPATLPGGKDNEETSSLSRLKPVSPGTITCPLRTPG
Sbjct: 541 KKAGIPRDSYSGDALYDLYADPDGSPATLPGGKDNEETSSLSRLKPVSPGTITCPLRTPG 600

Query: 601 SLLKDSKIPISIKHLTNLPSSHPVVHQQPSRSEMPRTKIPVSKVLVRRVSNRGLAGTTIR 660
           SLLKDSKIPISIKHLTNLPSSHPVVHQQPSRSEMPRTKIPVSKVLVRRVSNRGLAGTTIR
Sbjct: 601 SLLKDSKIPISIKHLTNLPSSHPVVHQQPSRSEMPRTKIPVSKVLVRRVSNRGLAGTTIR 660

Query: 661 ATACHDSAKKL 671
           ATACHDSAKKL
Sbjct: 661 ATACHDSAKKL 671


>gi|40288199 hypothetical protein LOC219287 isoform 2 [Homo sapiens]
          Length = 552

 Score =  757 bits (1954), Expect = 0.0
 Identities = 429/681 (62%), Positives = 453/681 (66%), Gaps = 139/681 (20%)

Query: 1   METSRSRGGGGAVSERGGAGASVGVCRRKAEAGAGTGTLAADMDLHCDCAAETPAAEPPS 60
           METSRSRGGGGAVSERGGAGASVGVCRRKAEAGAGTGTLAADMDLHCDCAAETPAAEPPS
Sbjct: 1   METSRSRGGGGAVSERGGAGASVGVCRRKAEAGAGTGTLAADMDLHCDCAAETPAAEPPS 60

Query: 61  GKINKAAFKLFKKRKSGGTMPSIFGVKNKGDGKSSGPTGLVRSRTHDGLAEVLVLESGRK 120
           GKINKAAFKLFKKRKSGGTMPSIFGVK                                 
Sbjct: 61  GKINKAAFKLFKKRKSGGTMPSIFGVK--------------------------------- 87

Query: 121 EEPRGGGDSGGGGGGRPNPGPPRAAGPGGGSLASSSVAKSHSFFS--LLKKNGRSENGKG 178
                            N G  +++GP G  L  S   ++H   +  L+ ++GR E  +G
Sbjct: 88  -----------------NKGDGKSSGPTG--LVRS---RTHDGLAEVLVLESGRKEEPRG 125

Query: 179 EPVDASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEGRAPGGGLILPGSLTAS---LE 235
                   GG+   G                          PGGG +   S+  S     
Sbjct: 126 GGDSGGGGGGRPNPG--------------------PPRAAGPGGGSLASSSVAKSHSFFS 165

Query: 236 CVKEETPRAAREPEEPSQDAPRDPAGEPAGGEEVPAPADRAPARSCREAEGLA-----HP 290
            +K+                     G    G+  P  A +A  +  R   GL      H 
Sbjct: 166 LLKKN--------------------GRSENGKGEPVDASKAGGKQKRGLRGLFSGMRWHR 205

Query: 291 GDTGARGEDAAGHRRAEPGPGEVRTAEDASRTGAVPVKTVPLVDSEGGSGRAPAAPDPAS 350
            D  A+ E A G     PG G +      +    V  +T           RA   P+  S
Sbjct: 206 KDKRAKAEAAEGRA---PGGGLILPGSLTASLECVKEETP----------RAAREPEEPS 252

Query: 351 VDPPSDPSADRICLMFSDVTSLKSFDSLTGCGDIIADQEEEAGPSCDKHVPGPGKPALSK 410
            D P DP+                     GCGDIIADQEEEAGPSCDKHVPGPGKPALSK
Sbjct: 253 QDAPRDPA---------------------GCGDIIADQEEEAGPSCDKHVPGPGKPALSK 291

Query: 411 KNPGVVAYQGGGEEMASPDEVDDTYLQEFWDMLSQTEEQGPEPQEGAAKVAAALETKVVP 470
           KNPGVVAYQGGGEEMASPDEVDDTYLQEFWDMLSQTEEQGPEPQEGAAKVAAALETKVVP
Sbjct: 292 KNPGVVAYQGGGEEMASPDEVDDTYLQEFWDMLSQTEEQGPEPQEGAAKVAAALETKVVP 351

Query: 471 ETPKDTRCVEAAKDASSVKRRRLNRIPIEPHPKEEPKHPEKEQQEGVPNSDEGYWDSTTP 530
           ETPKDTRCVEAAKDASSVKRRRLNRIPIEPHPKEEPKHPEKEQQEGVPNSDEGYWDSTTP
Sbjct: 352 ETPKDTRCVEAAKDASSVKRRRLNRIPIEPHPKEEPKHPEKEQQEGVPNSDEGYWDSTTP 411

Query: 531 GPEEDSSSSGKKAGIPRDSYSGDALYDLYADPDGSPATLPGGKDNEETSSLSRLKPVSPG 590
           GPEEDSSSSGKKAGIPRDSYSGDALYDLYADPDGSPATLPGGKDNEETSSLSRLKPVSPG
Sbjct: 412 GPEEDSSSSGKKAGIPRDSYSGDALYDLYADPDGSPATLPGGKDNEETSSLSRLKPVSPG 471

Query: 591 TITCPLRTPGSLLKDSKIPISIKHLTNLPSSHPVVHQQPSRSEMPRTKIPVSKVLVRRVS 650
           TITCPLRTPGSLLKDSKIPISIKHLTNLPSSHPVVHQQPSRSEMPRTKIPVSKVLVRRVS
Sbjct: 472 TITCPLRTPGSLLKDSKIPISIKHLTNLPSSHPVVHQQPSRSEMPRTKIPVSKVLVRRVS 531

Query: 651 NRGLAGTTIRATACHDSAKKL 671
           NRGLAGTTIRATACHDSAKKL
Sbjct: 532 NRGLAGTTIRATACHDSAKKL 552


>gi|124244056 family with sequence similarity 123B [Homo sapiens]
          Length = 1135

 Score =  209 bits (531), Expect = 9e-54
 Identities = 196/603 (32%), Positives = 274/603 (45%), Gaps = 109/603 (18%)

Query: 1   METSRSRGGGGAVSERGGAGASVGVCRRKAEAGAGTGTLAADMDLHCDCAAETPAAEPPS 60
           MET +        ++  GA AS     + AE GA     AA+       A E P +EP S
Sbjct: 1   METQKDEA-----AQAKGAAASGSTREQTAEKGAKNK--AAE-------ATEGPTSEPSS 46

Query: 61  ---GKINKAAFKLFKKRKSGGTMPSIFGV-KNKGDGKSSGPTGLVRSRTHDGLAEVLVLE 116
              G++ K A KLF  +K   T+PS FG  ++KG GK S   GL +S+THDGL+E     
Sbjct: 47  SGPGRLKKTAMKLFGGKKGICTLPSFFGGGRSKGSGKGSSKKGLSKSKTHDGLSEAA--- 103

Query: 117 SGRKEEPRGGGD--SGGGGGGRPNPGPP---RAAGPGGGSLASSSVAKSHSFFSLLKKNG 171
                   G  D  S G G   P P  P    ++    G+L + S  K+          G
Sbjct: 104 -------HGPEDVVSEGTGFSLPLPELPCQFPSSQSAHGALETGSRCKT-------SVAG 149

Query: 172 RSENGKGEPVDASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEGRAPGGGLIL--PGS 229
            +E    E   +     K K+GL+G FS +R HRK K   AE +E  A G   +   P  
Sbjct: 150 ATEKAVAEKFPSMP---KPKKGLKGFFSSIRRHRKSKVTGAEQSEPGAKGPERVRARPHE 206

Query: 230 LTASLECVK--EETPRAAREPEEPSQDAPRDPAGEPAGGEEVPAPADRAPAR---SCREA 284
             +S   V   EET +A R+     QDAP        G +  P P    PA    +C++ 
Sbjct: 207 HVSSAPQVPCFEETFQAPRKENANPQDAP--------GPKVSPTPEPSPPATEKMACKDP 258

Query: 285 EGLAHPGDTGARGEDAAGHRRAEPGPGEVRTAEDASRTGAVPVKTVPLVDSEGGSGRAPA 344
           E          +  +A      +P P    ++ +   +     K V              
Sbjct: 259 E----------KPMEACASAHVQPKPAPEASSLEEPHSPETGEKVVA------------- 295

Query: 345 APDPASVDPPSDPSADRICLMFSDVTSLKSFDSLTGCGDIIADQEEEAGPSCDKHVPGPG 404
                 V+PP+ P  D + L+F DVTSLKSFDSLTGCGDIIA+Q+ +   S    +   G
Sbjct: 296 ----GEVNPPNGPVGDPLSLLFGDVTSLKSFDSLTGCGDIIAEQDMD---SMTDSMASGG 348

Query: 405 KPAL---SKKNPGVVAYQGGGEEMASPDEVDDTYLQEFWDMLSQTEEQGPEPQEGAAKVA 461
           + A    +K++  +V YQGGGEEMA PD+ D+   +E    L + EE+  E +E      
Sbjct: 349 QRANRDGTKRSSCLVTYQGGGEEMALPDDDDEEEEEEEEVELEEEEEEVKEEEEDD---- 404

Query: 462 AALETKVVPET----PKDTRCVEAAKDASSVKRRRLNRIPIEPHPKEEPKH---PEKEQQ 514
              + + + ET    P+    +      S      +   P+  +P   P     P+ +QQ
Sbjct: 405 ---DLEYLWETAQMYPRPNMNLGYHPTTSPGHHGYMLLDPVRSYPGLAPGELLTPQSDQQ 461

Query: 515 EGVPNSDEGYWDSTTPGPEEDSSSS---GKKAGIPRDSYSGDALYDLYADPDGSPATLPG 571
           E  PNSDEGY+DSTTPG E+DS  +    ++  +PRDSYSGDALY+ Y +PD S    P 
Sbjct: 462 ESAPNSDEGYYDSTTPGFEDDSGEALGLVRRDCLPRDSYSGDALYEFY-EPDDSLENSPP 520

Query: 572 GKD 574
           G D
Sbjct: 521 GDD 523


>gi|157427665 hypothetical protein LOC205147 [Homo sapiens]
          Length = 861

 Score =  112 bits (281), Expect = 8e-25
 Identities = 131/459 (28%), Positives = 183/459 (39%), Gaps = 112/459 (24%)

Query: 191 KRGLRGLFSGMRW-HRK--DKRAKAEAAEGRAPGGGLILPGSLTASLECVKEETPRAARE 247
           KRG   + S ++  H K  D  A A A EG  P    +LPG          E+ P+A+  
Sbjct: 4   KRGKTFIKSSLQVSHEKPPDPAAVAAAREGTGPWS--VLPGGQQRPHS---EKGPQASPS 58

Query: 248 PEE----PSQDAPRDPAGEPAGGEEVPAPADRAPARSCREAEGLAHPGDTGARGEDAAGH 303
            +E    P++ A  DP G PA        A   P R C+  + ++  G   A      G 
Sbjct: 59  AQEYDRCPNKGAQLDPKGGPAA----LCGATFKPVRKCKTHDSMSGAGRATAATGQLVGS 114

Query: 304 RRAEPGPGEVRTAEDASRTGAVP-----VKTVPL-------------------------- 332
                 PG  R  +       +P      K++P                           
Sbjct: 115 ASFPGSPGSRRMIDYRHFVPQMPFVPAVAKSIPRKRISLKRPKKCFRNLFHIRRNKTEDL 174

Query: 333 --VDSEGGSGRAPAAP-DP------ASVDPPSDPSADRIC------------------LM 365
             + +EG S  +P  P DP      A + P   P  D +C                   +
Sbjct: 175 ASLAAEGKSLPSPGDPSDPGGRRSKAFLPPGEGPGLDGLCQDLLDSELLADASFGLCRAL 234

Query: 366 FSDVTSLKSFDSLTGCGDIIADQEEEAGPSCDKHVPGPGKPA-----LSKKNPGVVAYQG 420
             DV SL+SFDSLTGCG++ AD  E + PS + +  GP  P      L  K P     QG
Sbjct: 235 CEDVASLQSFDSLTGCGEVFAD--ESSVPSLELN-EGPESPTQAAQGLESKVPRG-PLQG 290

Query: 421 GGEEMASPDEVDDTYLQEFWDMLSQTEEQ------GP--EPQEGAAKVAAALETKVVPET 472
             E++ASP + + +    FWD ++++  Q      GP     +G  +  + L+T  + E 
Sbjct: 291 SVEQLASPAQNEASDFTRFWDSVNRSVRQQQRALLGPWLSGPQGTDRDQSRLDTAGLAEL 350

Query: 473 PK-DTRCVEAAKDASSVKRRRLNRIPIEPHPKEEPKHPEKEQQEGVPNSDEGYWDSTTPG 531
           P    R   +   ASS+                +   P+ EQ E V  SDEGY+DS +PG
Sbjct: 351 PLCPCRDPRSGSKASSI----------------DTGTPKSEQPESVSTSDEGYYDSFSPG 394

Query: 532 PEED----SSSSGKKAGIPRDSYSGDALYDLYADPDGSP 566
            EED     S     A  PRDSYSGDALY+L+ DP   P
Sbjct: 395 LEEDKKEAESPGTPAATFPRDSYSGDALYELFHDPSEGP 433


>gi|157427663 hypothetical protein LOC205147 [Homo sapiens]
          Length = 861

 Score =  112 bits (281), Expect = 8e-25
 Identities = 131/459 (28%), Positives = 183/459 (39%), Gaps = 112/459 (24%)

Query: 191 KRGLRGLFSGMRW-HRK--DKRAKAEAAEGRAPGGGLILPGSLTASLECVKEETPRAARE 247
           KRG   + S ++  H K  D  A A A EG  P    +LPG          E+ P+A+  
Sbjct: 4   KRGKTFIKSSLQVSHEKPPDPAAVAAAREGTGPWS--VLPGGQQRPHS---EKGPQASPS 58

Query: 248 PEE----PSQDAPRDPAGEPAGGEEVPAPADRAPARSCREAEGLAHPGDTGARGEDAAGH 303
            +E    P++ A  DP G PA        A   P R C+  + ++  G   A      G 
Sbjct: 59  AQEYDRCPNKGAQLDPKGGPAA----LCGATFKPVRKCKTHDSMSGAGRATAATGQLVGS 114

Query: 304 RRAEPGPGEVRTAEDASRTGAVP-----VKTVPL-------------------------- 332
                 PG  R  +       +P      K++P                           
Sbjct: 115 ASFPGSPGSRRMIDYRHFVPQMPFVPAVAKSIPRKRISLKRPKKCFRNLFHIRRNKTEDL 174

Query: 333 --VDSEGGSGRAPAAP-DP------ASVDPPSDPSADRIC------------------LM 365
             + +EG S  +P  P DP      A + P   P  D +C                   +
Sbjct: 175 ASLAAEGKSLPSPGDPSDPGGRRSKAFLPPGEGPGLDGLCQDLLDSELLADASFGLCRAL 234

Query: 366 FSDVTSLKSFDSLTGCGDIIADQEEEAGPSCDKHVPGPGKPA-----LSKKNPGVVAYQG 420
             DV SL+SFDSLTGCG++ AD  E + PS + +  GP  P      L  K P     QG
Sbjct: 235 CEDVASLQSFDSLTGCGEVFAD--ESSVPSLELN-EGPESPTQAAQGLESKVPRG-PLQG 290

Query: 421 GGEEMASPDEVDDTYLQEFWDMLSQTEEQ------GP--EPQEGAAKVAAALETKVVPET 472
             E++ASP + + +    FWD ++++  Q      GP     +G  +  + L+T  + E 
Sbjct: 291 SVEQLASPAQNEASDFTRFWDSVNRSVRQQQRALLGPWLSGPQGTDRDQSRLDTAGLAEL 350

Query: 473 PK-DTRCVEAAKDASSVKRRRLNRIPIEPHPKEEPKHPEKEQQEGVPNSDEGYWDSTTPG 531
           P    R   +   ASS+                +   P+ EQ E V  SDEGY+DS +PG
Sbjct: 351 PLCPCRDPRSGSKASSI----------------DTGTPKSEQPESVSTSDEGYYDSFSPG 394

Query: 532 PEED----SSSSGKKAGIPRDSYSGDALYDLYADPDGSP 566
            EED     S     A  PRDSYSGDALY+L+ DP   P
Sbjct: 395 LEEDKKEAESPGTPAATFPRDSYSGDALYELFHDPSEGP 433


>gi|157427661 hypothetical protein LOC205147 [Homo sapiens]
          Length = 861

 Score =  112 bits (281), Expect = 8e-25
 Identities = 131/459 (28%), Positives = 183/459 (39%), Gaps = 112/459 (24%)

Query: 191 KRGLRGLFSGMRW-HRK--DKRAKAEAAEGRAPGGGLILPGSLTASLECVKEETPRAARE 247
           KRG   + S ++  H K  D  A A A EG  P    +LPG          E+ P+A+  
Sbjct: 4   KRGKTFIKSSLQVSHEKPPDPAAVAAAREGTGPWS--VLPGGQQRPHS---EKGPQASPS 58

Query: 248 PEE----PSQDAPRDPAGEPAGGEEVPAPADRAPARSCREAEGLAHPGDTGARGEDAAGH 303
            +E    P++ A  DP G PA        A   P R C+  + ++  G   A      G 
Sbjct: 59  AQEYDRCPNKGAQLDPKGGPAA----LCGATFKPVRKCKTHDSMSGAGRATAATGQLVGS 114

Query: 304 RRAEPGPGEVRTAEDASRTGAVP-----VKTVPL-------------------------- 332
                 PG  R  +       +P      K++P                           
Sbjct: 115 ASFPGSPGSRRMIDYRHFVPQMPFVPAVAKSIPRKRISLKRPKKCFRNLFHIRRNKTEDL 174

Query: 333 --VDSEGGSGRAPAAP-DP------ASVDPPSDPSADRIC------------------LM 365
             + +EG S  +P  P DP      A + P   P  D +C                   +
Sbjct: 175 ASLAAEGKSLPSPGDPSDPGGRRSKAFLPPGEGPGLDGLCQDLLDSELLADASFGLCRAL 234

Query: 366 FSDVTSLKSFDSLTGCGDIIADQEEEAGPSCDKHVPGPGKPA-----LSKKNPGVVAYQG 420
             DV SL+SFDSLTGCG++ AD  E + PS + +  GP  P      L  K P     QG
Sbjct: 235 CEDVASLQSFDSLTGCGEVFAD--ESSVPSLELN-EGPESPTQAAQGLESKVPRG-PLQG 290

Query: 421 GGEEMASPDEVDDTYLQEFWDMLSQTEEQ------GP--EPQEGAAKVAAALETKVVPET 472
             E++ASP + + +    FWD ++++  Q      GP     +G  +  + L+T  + E 
Sbjct: 291 SVEQLASPAQNEASDFTRFWDSVNRSVRQQQRALLGPWLSGPQGTDRDQSRLDTAGLAEL 350

Query: 473 PK-DTRCVEAAKDASSVKRRRLNRIPIEPHPKEEPKHPEKEQQEGVPNSDEGYWDSTTPG 531
           P    R   +   ASS+                +   P+ EQ E V  SDEGY+DS +PG
Sbjct: 351 PLCPCRDPRSGSKASSI----------------DTGTPKSEQPESVSTSDEGYYDSFSPG 394

Query: 532 PEED----SSSSGKKAGIPRDSYSGDALYDLYADPDGSP 566
            EED     S     A  PRDSYSGDALY+L+ DP   P
Sbjct: 395 LEEDKKEAESPGTPAATFPRDSYSGDALYELFHDPSEGP 433


>gi|157427667 hypothetical protein LOC205147 [Homo sapiens]
          Length = 861

 Score =  112 bits (281), Expect = 8e-25
 Identities = 131/459 (28%), Positives = 183/459 (39%), Gaps = 112/459 (24%)

Query: 191 KRGLRGLFSGMRW-HRK--DKRAKAEAAEGRAPGGGLILPGSLTASLECVKEETPRAARE 247
           KRG   + S ++  H K  D  A A A EG  P    +LPG          E+ P+A+  
Sbjct: 4   KRGKTFIKSSLQVSHEKPPDPAAVAAAREGTGPWS--VLPGGQQRPHS---EKGPQASPS 58

Query: 248 PEE----PSQDAPRDPAGEPAGGEEVPAPADRAPARSCREAEGLAHPGDTGARGEDAAGH 303
            +E    P++ A  DP G PA        A   P R C+  + ++  G   A      G 
Sbjct: 59  AQEYDRCPNKGAQLDPKGGPAA----LCGATFKPVRKCKTHDSMSGAGRATAATGQLVGS 114

Query: 304 RRAEPGPGEVRTAEDASRTGAVP-----VKTVPL-------------------------- 332
                 PG  R  +       +P      K++P                           
Sbjct: 115 ASFPGSPGSRRMIDYRHFVPQMPFVPAVAKSIPRKRISLKRPKKCFRNLFHIRRNKTEDL 174

Query: 333 --VDSEGGSGRAPAAP-DP------ASVDPPSDPSADRIC------------------LM 365
             + +EG S  +P  P DP      A + P   P  D +C                   +
Sbjct: 175 ASLAAEGKSLPSPGDPSDPGGRRSKAFLPPGEGPGLDGLCQDLLDSELLADASFGLCRAL 234

Query: 366 FSDVTSLKSFDSLTGCGDIIADQEEEAGPSCDKHVPGPGKPA-----LSKKNPGVVAYQG 420
             DV SL+SFDSLTGCG++ AD  E + PS + +  GP  P      L  K P     QG
Sbjct: 235 CEDVASLQSFDSLTGCGEVFAD--ESSVPSLELN-EGPESPTQAAQGLESKVPRG-PLQG 290

Query: 421 GGEEMASPDEVDDTYLQEFWDMLSQTEEQ------GP--EPQEGAAKVAAALETKVVPET 472
             E++ASP + + +    FWD ++++  Q      GP     +G  +  + L+T  + E 
Sbjct: 291 SVEQLASPAQNEASDFTRFWDSVNRSVRQQQRALLGPWLSGPQGTDRDQSRLDTAGLAEL 350

Query: 473 PK-DTRCVEAAKDASSVKRRRLNRIPIEPHPKEEPKHPEKEQQEGVPNSDEGYWDSTTPG 531
           P    R   +   ASS+                +   P+ EQ E V  SDEGY+DS +PG
Sbjct: 351 PLCPCRDPRSGSKASSI----------------DTGTPKSEQPESVSTSDEGYYDSFSPG 394

Query: 532 PEED----SSSSGKKAGIPRDSYSGDALYDLYADPDGSP 566
            EED     S     A  PRDSYSGDALY+L+ DP   P
Sbjct: 395 LEEDKKEAESPGTPAATFPRDSYSGDALYELFHDPSEGP 433


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
            sapiens]
          Length = 1487

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 96/349 (27%), Positives = 119/349 (34%), Gaps = 49/349 (14%)

Query: 89   KGDGKSSGPTGLVRSRTHDGLAEVLVLESGRKEE--PRGGGDSGGGG-----GGRPNPGP 141
            KGD  + GP G   +    G   V   +  R  +  P   G  G  G     G   NPGP
Sbjct: 857  KGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGP 916

Query: 142  PRAAGPGG----GSLASSSVAKSHSFFSLLKKNGRSENGKGEPVDASKAGGKQKRGLRGL 197
            P   GP G          S     +    L+        KGEP D   +G +   G +GL
Sbjct: 917  PGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGL 976

Query: 198  FSGMRWHRKDKRAKAEAAEGRAPGGGLILPGSLTASLECVKEETPRAAREPEEPSQDAP- 256
                   R       +  E   PG    LPG    S E  K+  P A+ +   P    P 
Sbjct: 977  AG----QRGIVGLPGQRGERGFPG----LPG---PSGEPGKQGAPGASGDRGPPGPVGPP 1025

Query: 257  --RDPAGEPAGGEEVPAPADRAPARSCREAEGL-AHPGDTGARGEDAAGHRRAEPGP-GE 312
                PAGEP  G E    AD  P R    A G+    G+TGA G   A      PGP G 
Sbjct: 1026 GLTGPAGEP--GREGSPGADGPPGRD--GAAGVKGDRGETGAVGAPGAPGPPGSPGPAGP 1081

Query: 313  VRTAEDASRTGAVPVKTVPLVDSEGGSGRAPAAPDPA-SVDPPSDPSADRICLMFSDVTS 371
                 D    GA           +G  G  P+ P  A  +  P  P  D+          
Sbjct: 1082 TGKQGDRGEAGA-----------QGPMG--PSGPAGARGIQGPQGPRGDKGEAGEPGERG 1128

Query: 372  LKSFDSLTGCGDIIADQEEEAGPSCDKHVPGPGKPALSKKNPGVVAYQG 420
            LK     TG    +       GPS D+   GP  P+  +  PG V   G
Sbjct: 1129 LKGHRGFTG----LQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSG 1173



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 98/415 (23%), Positives = 127/415 (30%), Gaps = 70/415 (16%)

Query: 36  TGTLAADMDLHCDCAAETPAAEPPSGK--------INKAAFKLFKKRKSG--GTMPSIFG 85
           TGT+  D D+ C+   +  + E P G+        +  A+ +   K + G  G +  I G
Sbjct: 59  TGTVLCD-DIICEDVKDCLSPEIPFGECCPICPTDLATASGQPGPKGQKGEPGDIKDIVG 117

Query: 86  VKNKGDGKSSGPTGLVRSRTHDGLAEVLVLESGRKEEP--RGGGDSGGGGGGRPNPGPPR 143
            K  G     GP G    R   G       + G K  P  RG     G  G    PGPP 
Sbjct: 118 PK--GPPGPQGPAGEQGPRGDRG-------DKGEKGAPGPRGRDGEPGTPGNPGPPGPPG 168

Query: 144 AAGPGGGSLASSSVAKSHSFFSLLKKNGRSENGKGEPVDASKAGGKQKRGLRGLFSGMRW 203
             GP G  L  +  A+    F                    KAGG Q   ++G    M  
Sbjct: 169 PPGPPG--LGGNFAAQMAGGFD------------------EKAGGAQLGVMQGPMGPMGP 208

Query: 204 HRKDKRAKAEAAEGRAPGGGLILPGSLTASLECVKEETPRAAREPEEPSQDAPRDPAGE- 262
                 A A   +G     G   PG    S        P    +P +  +      AGE 
Sbjct: 209 RGPPGPAGAPGPQGFQGNPG--EPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGER 266

Query: 263 ----PAGGEEVPAPADRAPARSCREAEGL----AHPGDTGARGEDAAGHRRAEPGP-GEV 313
               P G    P        +  R   GL       G  G +GE  +      PGP G  
Sbjct: 267 GPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPR 326

Query: 314 RTAEDASRTGAVPVKTVPLVDSEGGSGRAPAAPDPASVDPPSDPSADRICLMFSDVTSLK 373
               +  RTG           + G  G+   A  P  V P   P        F      K
Sbjct: 327 GLPGERGRTGPAGA-----AGARGNDGQPGPAGPPGPVGPAGGPG-------FPGAPGAK 374

Query: 374 SFDSLTGCGDIIADQEEEAGPSCDKHVPGPGKPALSKKNPGVVAYQGGGEEMASP 428
                TG        E   GP  +   PG   PA +  NPG     G      +P
Sbjct: 375 GEAGPTGA----RGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAP 425



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 103/409 (25%), Positives = 128/409 (31%), Gaps = 81/409 (19%)

Query: 7    RGGGGAVSERGGAGASVGVCRRKAEAGAGT-GTLAADMDLHCDCAAETPAAEPPSGKINK 65
            RG  G   ERG  GA      +  +   G  GT   D        A  P A+ P G    
Sbjct: 698  RGERGFPGERGSPGA------QGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGM 751

Query: 66   AAFKLFKKRKSGGTMPSIFGVK-NKGDGKSSGPTGLVRSRTHDGLAEVL-----VLESGR 119
                   +R + G    I G K ++GD    GP G        GL   +        +G 
Sbjct: 752  PG-----ERGAAG----IAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGE 802

Query: 120  KEE-----PRGGGDSGGGGGGRPNPGPPRAAGPGGGSLASSSVAKSHSFFSLLKKNGRSE 174
            K E     P G   + G  G R   GPP  AG  G   A              +K     
Sbjct: 803  KGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGA 862

Query: 175  NGKGEPVDA-------SKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEGRAPGGGLILP 227
             G   P  A          G K  RG +G      +     R     + G  PG     P
Sbjct: 863  PGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGN-PGP----P 917

Query: 228  GSLTASLECVKEETPRAAR-------EPEEPSQDAPRDPAGE--------PAGGEEVPAP 272
            G    S     ++ P+ AR          EP    P  P GE        P+G E  P P
Sbjct: 918  GPPGPS----GKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGP 973

Query: 273  ADRAPARSC---------REAEGLAHP-GDTGARGEDAAGHRRAEPG----PGEVRTAED 318
               A  R           R   GL  P G+ G +G   A   R  PG    PG    A +
Sbjct: 974  QGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGE 1033

Query: 319  ASRTGAVPVKTVPLVD---------SEGGSGRAPAAPDPASVDPPSDPS 358
              R G+      P  D          E G+  AP AP P     P+ P+
Sbjct: 1034 PGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPT 1082



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 85/313 (27%), Positives = 107/313 (34%), Gaps = 54/313 (17%)

Query: 124 RGGGDSGGGGGGRPNPGPPRAAGP-------GGGSLASSSVAKSHSFFSLLKKNGRSENG 176
           RG     G  G R N G P  AGP       GG     +  AK  +  +  +    ++  
Sbjct: 332 RGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGP 391

Query: 177 KGEPVDASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEGRAPG-GGLILPGSLTASLE 235
           +GEP      G     G  G   G+   +    A   A     PG  G   P   T  L 
Sbjct: 392 RGEPGTPGSPGPAGASGNPGT-DGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLG 450

Query: 236 CVKEETPRAAREPEEPSQDAPRDPAGE--PAGGEEVPAPADRAPARSCREAEGLAHPGDT 293
             K +T     EP        + P GE  PAG +  P PA     R  R   G    G  
Sbjct: 451 -PKGQT----GEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPG--GVGPI 503

Query: 294 GARGEDAAGHRRAEPGPGEVRTAEDASRTGAVPVKTVPLVDSEGGSGRAPAAPDPASVDP 353
           G  GE  A   R  PG           + G    K  P     G SG   A P  A+ DP
Sbjct: 504 GPPGERGAPGNRGFPG-----------QDGLAGPKGAP--GERGPSGL--AGPKGANGDP 548

Query: 354 --PSDPSADRICLMFSDVTSLKSFDSLTG-CGDIIADQEEEAGPS---CDKHVPGPGKPA 407
             P +P              L     LTG  GD  A  + + GPS    +   PGP  P 
Sbjct: 549 GRPGEP-------------GLPGARGLTGRPGD--AGPQGKVGPSGAPGEDGRPGPPGPQ 593

Query: 408 LSKKNPGVVAYQG 420
            ++  PGV+ + G
Sbjct: 594 GARGQPGVMGFPG 606



 Score = 39.3 bits (90), Expect = 0.012
 Identities = 69/281 (24%), Positives = 91/281 (32%), Gaps = 47/281 (16%)

Query: 90  GDGKSSGPTGLVRSRTHDGLAEVLVLESGRKEEPRGGGDSGGGG--GGRPNPGPPRAAGP 147
           G   S GP G   +   DG+        G K      G +G  G  G R  PGP  A GP
Sbjct: 396 GTPGSPGPAGASGNPGTDGIP-------GAKGSAGAPGIAGAPGFPGPRGPPGPQGATGP 448

Query: 148 GG--GSLASSSVAKSHSFFSLLKKNGRSENGKGEPVDA-SKAGGKQKRGLRGLFSGMR-- 202
            G  G      +A         ++  + E G   P  A   AG + KRG RG   G+   
Sbjct: 449 LGPKGQTGEPGIAGFKG-----EQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPI 503

Query: 203 -------------WHRKDKRAKAEAAEGRAPGGGLILPGSLTASLECVKEE-TPRAAREP 248
                        +  +D  A  + A G     GL  P           E   P A    
Sbjct: 504 GPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLT 563

Query: 249 EEPSQDAPRDPAGEPAGGEEVPAPADRAPARSCREAEGLAHPGDTGARGEDAAGHRRAEP 308
             P    P+   G      E   P    P  +  +   +  PG  GA GE          
Sbjct: 564 GRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGE---------- 613

Query: 309 GPGEVRTAEDASRTGAVPVKTVPLVDSEGGSGRAPAAPDPA 349
            PG+   A +    GA  ++ +P  D E G+   P    PA
Sbjct: 614 -PGK---AGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPA 650



 Score = 36.2 bits (82), Expect = 0.10
 Identities = 59/241 (24%), Positives = 78/241 (32%), Gaps = 21/241 (8%)

Query: 124 RGGGDSGGGGGGRPNPGPPRAAGPGGGSLASSSVAKSHSFFSLLKKNGRSENGKGEPVDA 183
           RG   + G  G +  PGPP   G  GG      V        L+   G     +G P + 
Sbjct: 653 RGEQGAPGPSGFQGLPGPPGPPGE-GGKPGDQGVPGEAGAPGLVGPRGE----RGFPGER 707

Query: 184 SKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAE--GRAPGGGLILPGSLTASLECVKEET 241
              G +  +G RGL  G       K A   A     + P G   +PG   A+        
Sbjct: 708 GSPGAQGLQGPRGL-PGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAA-------- 758

Query: 242 PRAAREPEEPSQDAPRDPAGEPA--GGEEVPAP-ADRAPARSCREAEGLAHPGDTGARGE 298
              A    +      + P G P   GG  +  P     PA +  E   +  PG  G+ G 
Sbjct: 759 -GIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGA 817

Query: 299 DAAGHRRAEPG-PGEVRTAEDASRTGAVPVKTVPLVDSEGGSGRAPAAPDPASVDPPSDP 357
             A   R E G PG    A      G    K       + G   AP    P+    P  P
Sbjct: 818 RGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGP 877

Query: 358 S 358
           +
Sbjct: 878 T 878



 Score = 30.8 bits (68), Expect = 4.2
 Identities = 15/36 (41%), Positives = 17/36 (47%)

Query: 123  PRGGGDSGGGGGGRPNPGPPRAAGPGGGSLASSSVA 158
            PRG     G  G   NPGPP   GP G  +  S+ A
Sbjct: 1189 PRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFA 1224


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
            sapiens]
          Length = 1418

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 96/349 (27%), Positives = 119/349 (34%), Gaps = 49/349 (14%)

Query: 89   KGDGKSSGPTGLVRSRTHDGLAEVLVLESGRKEE--PRGGGDSGGGG-----GGRPNPGP 141
            KGD  + GP G   +    G   V   +  R  +  P   G  G  G     G   NPGP
Sbjct: 788  KGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGP 847

Query: 142  PRAAGPGG----GSLASSSVAKSHSFFSLLKKNGRSENGKGEPVDASKAGGKQKRGLRGL 197
            P   GP G          S     +    L+        KGEP D   +G +   G +GL
Sbjct: 848  PGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGL 907

Query: 198  FSGMRWHRKDKRAKAEAAEGRAPGGGLILPGSLTASLECVKEETPRAAREPEEPSQDAP- 256
                   R       +  E   PG    LPG    S E  K+  P A+ +   P    P 
Sbjct: 908  AG----QRGIVGLPGQRGERGFPG----LPG---PSGEPGKQGAPGASGDRGPPGPVGPP 956

Query: 257  --RDPAGEPAGGEEVPAPADRAPARSCREAEGL-AHPGDTGARGEDAAGHRRAEPGP-GE 312
                PAGEP  G E    AD  P R    A G+    G+TGA G   A      PGP G 
Sbjct: 957  GLTGPAGEP--GREGSPGADGPPGRD--GAAGVKGDRGETGAVGAPGAPGPPGSPGPAGP 1012

Query: 313  VRTAEDASRTGAVPVKTVPLVDSEGGSGRAPAAPDPA-SVDPPSDPSADRICLMFSDVTS 371
                 D    GA           +G  G  P+ P  A  +  P  P  D+          
Sbjct: 1013 TGKQGDRGEAGA-----------QGPMG--PSGPAGARGIQGPQGPRGDKGEAGEPGERG 1059

Query: 372  LKSFDSLTGCGDIIADQEEEAGPSCDKHVPGPGKPALSKKNPGVVAYQG 420
            LK     TG    +       GPS D+   GP  P+  +  PG V   G
Sbjct: 1060 LKGHRGFTG----LQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSG 1104



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 83/352 (23%), Positives = 101/352 (28%), Gaps = 57/352 (16%)

Query: 89  KGDGKSSGPTGLVRSRTHDGLAEVLVLESGRKEEP--RGGGDSGGGGGGRPNPGPPRAAG 146
           KG     GP G    R   G       + G K  P  RG     G  G    PGPP   G
Sbjct: 50  KGPPGPQGPAGEQGPRGDRG-------DKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPG 102

Query: 147 PGGGSLASSSVAKSHSFFSLLKKNGRSENGKGEPVDASKAGGKQKRGLRGLFSGMRWHRK 206
           P G  L  +  A+    F                    KAGG Q   ++G    M     
Sbjct: 103 PPG--LGGNFAAQMAGGFD------------------EKAGGAQLGVMQGPMGPMGPRGP 142

Query: 207 DKRAKAEAAEGRAPGGGLILPGSLTASLECVKEETPRAAREPEEPSQDAPRDPAGE---- 262
              A A   +G     G   PG    S        P    +P +  +      AGE    
Sbjct: 143 PGPAGAPGPQGFQGNPG--EPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPP 200

Query: 263 -PAGGEEVPAPADRAPARSCREAEGL----AHPGDTGARGEDAAGHRRAEPGP-GEVRTA 316
            P G    P        +  R   GL       G  G +GE  +      PGP G     
Sbjct: 201 GPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLP 260

Query: 317 EDASRTGAVPVKTVPLVDSEGGSGRAPAAPDPASVDPPSDPSADRICLMFSDVTSLKSFD 376
            +  RTG           + G  G+   A  P  V P   P        F      K   
Sbjct: 261 GERGRTGPAGA-----AGARGNDGQPGPAGPPGPVGPAGGPG-------FPGAPGAKGEA 308

Query: 377 SLTGCGDIIADQEEEAGPSCDKHVPGPGKPALSKKNPGVVAYQGGGEEMASP 428
             TG        E   GP  +   PG   PA +  NPG     G      +P
Sbjct: 309 GPTGA----RGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAP 356



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 103/409 (25%), Positives = 128/409 (31%), Gaps = 81/409 (19%)

Query: 7    RGGGGAVSERGGAGASVGVCRRKAEAGAGT-GTLAADMDLHCDCAAETPAAEPPSGKINK 65
            RG  G   ERG  GA      +  +   G  GT   D        A  P A+ P G    
Sbjct: 629  RGERGFPGERGSPGA------QGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGM 682

Query: 66   AAFKLFKKRKSGGTMPSIFGVK-NKGDGKSSGPTGLVRSRTHDGLAEVL-----VLESGR 119
                   +R + G    I G K ++GD    GP G        GL   +        +G 
Sbjct: 683  PG-----ERGAAG----IAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGE 733

Query: 120  KEE-----PRGGGDSGGGGGGRPNPGPPRAAGPGGGSLASSSVAKSHSFFSLLKKNGRSE 174
            K E     P G   + G  G R   GPP  AG  G   A              +K     
Sbjct: 734  KGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGA 793

Query: 175  NGKGEPVDA-------SKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEGRAPGGGLILP 227
             G   P  A          G K  RG +G      +     R     + G  PG     P
Sbjct: 794  PGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGN-PGP----P 848

Query: 228  GSLTASLECVKEETPRAAR-------EPEEPSQDAPRDPAGE--------PAGGEEVPAP 272
            G    S     ++ P+ AR          EP    P  P GE        P+G E  P P
Sbjct: 849  GPPGPS----GKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGP 904

Query: 273  ADRAPARSC---------REAEGLAHP-GDTGARGEDAAGHRRAEPG----PGEVRTAED 318
               A  R           R   GL  P G+ G +G   A   R  PG    PG    A +
Sbjct: 905  QGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGE 964

Query: 319  ASRTGAVPVKTVPLVD---------SEGGSGRAPAAPDPASVDPPSDPS 358
              R G+      P  D          E G+  AP AP P     P+ P+
Sbjct: 965  PGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPT 1013



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 85/313 (27%), Positives = 107/313 (34%), Gaps = 54/313 (17%)

Query: 124 RGGGDSGGGGGGRPNPGPPRAAGP-------GGGSLASSSVAKSHSFFSLLKKNGRSENG 176
           RG     G  G R N G P  AGP       GG     +  AK  +  +  +    ++  
Sbjct: 263 RGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGP 322

Query: 177 KGEPVDASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEGRAPG-GGLILPGSLTASLE 235
           +GEP      G     G  G   G+   +    A   A     PG  G   P   T  L 
Sbjct: 323 RGEPGTPGSPGPAGASGNPGT-DGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLG 381

Query: 236 CVKEETPRAAREPEEPSQDAPRDPAGE--PAGGEEVPAPADRAPARSCREAEGLAHPGDT 293
             K +T     EP        + P GE  PAG +  P PA     R  R   G    G  
Sbjct: 382 -PKGQT----GEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPG--GVGPI 434

Query: 294 GARGEDAAGHRRAEPGPGEVRTAEDASRTGAVPVKTVPLVDSEGGSGRAPAAPDPASVDP 353
           G  GE  A   R  PG           + G    K  P     G SG   A P  A+ DP
Sbjct: 435 GPPGERGAPGNRGFPG-----------QDGLAGPKGAP--GERGPSGL--AGPKGANGDP 479

Query: 354 --PSDPSADRICLMFSDVTSLKSFDSLTG-CGDIIADQEEEAGPS---CDKHVPGPGKPA 407
             P +P              L     LTG  GD  A  + + GPS    +   PGP  P 
Sbjct: 480 GRPGEP-------------GLPGARGLTGRPGD--AGPQGKVGPSGAPGEDGRPGPPGPQ 524

Query: 408 LSKKNPGVVAYQG 420
            ++  PGV+ + G
Sbjct: 525 GARGQPGVMGFPG 537



 Score = 39.3 bits (90), Expect = 0.012
 Identities = 69/281 (24%), Positives = 91/281 (32%), Gaps = 47/281 (16%)

Query: 90  GDGKSSGPTGLVRSRTHDGLAEVLVLESGRKEEPRGGGDSGGGG--GGRPNPGPPRAAGP 147
           G   S GP G   +   DG+        G K      G +G  G  G R  PGP  A GP
Sbjct: 327 GTPGSPGPAGASGNPGTDGIP-------GAKGSAGAPGIAGAPGFPGPRGPPGPQGATGP 379

Query: 148 GG--GSLASSSVAKSHSFFSLLKKNGRSENGKGEPVDA-SKAGGKQKRGLRGLFSGMR-- 202
            G  G      +A         ++  + E G   P  A   AG + KRG RG   G+   
Sbjct: 380 LGPKGQTGEPGIAGFKG-----EQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPI 434

Query: 203 -------------WHRKDKRAKAEAAEGRAPGGGLILPGSLTASLECVKEE-TPRAAREP 248
                        +  +D  A  + A G     GL  P           E   P A    
Sbjct: 435 GPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLT 494

Query: 249 EEPSQDAPRDPAGEPAGGEEVPAPADRAPARSCREAEGLAHPGDTGARGEDAAGHRRAEP 308
             P    P+   G      E   P    P  +  +   +  PG  GA GE          
Sbjct: 495 GRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGE---------- 544

Query: 309 GPGEVRTAEDASRTGAVPVKTVPLVDSEGGSGRAPAAPDPA 349
            PG+   A +    GA  ++ +P  D E G+   P    PA
Sbjct: 545 -PGK---AGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPA 581



 Score = 36.2 bits (82), Expect = 0.10
 Identities = 59/241 (24%), Positives = 78/241 (32%), Gaps = 21/241 (8%)

Query: 124 RGGGDSGGGGGGRPNPGPPRAAGPGGGSLASSSVAKSHSFFSLLKKNGRSENGKGEPVDA 183
           RG   + G  G +  PGPP   G  GG      V        L+   G     +G P + 
Sbjct: 584 RGEQGAPGPSGFQGLPGPPGPPGE-GGKPGDQGVPGEAGAPGLVGPRGE----RGFPGER 638

Query: 184 SKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAE--GRAPGGGLILPGSLTASLECVKEET 241
              G +  +G RGL  G       K A   A     + P G   +PG   A+        
Sbjct: 639 GSPGAQGLQGPRGL-PGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAA-------- 689

Query: 242 PRAAREPEEPSQDAPRDPAGEPA--GGEEVPAP-ADRAPARSCREAEGLAHPGDTGARGE 298
              A    +      + P G P   GG  +  P     PA +  E   +  PG  G+ G 
Sbjct: 690 -GIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGA 748

Query: 299 DAAGHRRAEPG-PGEVRTAEDASRTGAVPVKTVPLVDSEGGSGRAPAAPDPASVDPPSDP 357
             A   R E G PG    A      G    K       + G   AP    P+    P  P
Sbjct: 749 RGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGP 808

Query: 358 S 358
           +
Sbjct: 809 T 809



 Score = 30.8 bits (68), Expect = 4.2
 Identities = 15/36 (41%), Positives = 17/36 (47%)

Query: 123  PRGGGDSGGGGGGRPNPGPPRAAGPGGGSLASSSVA 158
            PRG     G  G   NPGPP   GP G  +  S+ A
Sbjct: 1120 PRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFA 1155


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 53.5 bits (127), Expect = 6e-07
 Identities = 85/332 (25%), Positives = 110/332 (33%), Gaps = 53/332 (15%)

Query: 124 RGGGDSGGGGGGRPN----PGPPRAAG-PGGGSLASSSVAKSHSFFSLLKKNGRSENGKG 178
           + G D   G  GRP     PGP  A G PG   L      +  S     K +      KG
Sbjct: 228 KNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKG 287

Query: 179 EPVDASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEG----------RAPGGGLILPG 228
           EP    + G   + G RGL            A A   +G            P G    PG
Sbjct: 288 EPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPG 347

Query: 229 SLTASLECVKEETPRAAREPE----EPSQDAPRDPAGEPAGGEEVPAPADRAPARSCREA 284
           ++ A  E    + PR +  P+    EP    P   AG PAG    P    +  A+    A
Sbjct: 348 AVGAKGE-AGPQGPRGSEGPQGVRGEPGPPGPAGAAG-PAGN---PGADGQPGAKGANGA 402

Query: 285 EGLA-HPGDTGARGEDAAGHRRAEPGPGEVRTAEDASRTGAVPVKTVPLVDSEGGSGRAP 343
            G+A  PG  GARG          PGP       ++   GA          S+G +G A 
Sbjct: 403 PGIAGAPGFPGARGPSGPQGPGGPPGP-----KGNSGEPGA--------PGSKGDTG-AK 448

Query: 344 AAPDPASVDPPSDPSADRICLMFSDVTSLKSFDSLTGCGDIIADQEEEAGPSC-----DK 398
             P P  V  P  P+ +            +      G   +     E  GP         
Sbjct: 449 GEPGPVGVQGPPGPAGEE---------GKRGARGEPGPTGLPGPPGERGGPGSRGFPGAD 499

Query: 399 HVPGPGKPALSKKNPGVVAYQGGGEEMASPDE 430
            V GP  PA  + +PG    +G   E   P E
Sbjct: 500 GVAGPKGPAGERGSPGPAGPKGSPGEAGRPGE 531



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 142/580 (24%), Positives = 176/580 (30%), Gaps = 75/580 (12%)

Query: 44  DLHCDCAAETPAAEPPSGKINKAAFKLFKKRKSGGTMPSIFGVKN-KGDGKSSGPTGLVR 102
           D+ CD     P AE P G+       +        T     GV+  KGD    GP G   
Sbjct: 72  DVICDETKNCPGAEVPEGE----CCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAG 127

Query: 103 SRTHDGLAEVLVLESGRKEEPRGGGDSGGGG---------------GGRPNPGPPRAAGP 147
               DG+     L  G    P   G  G GG               GG   PGP   +GP
Sbjct: 128 PPGRDGIPGQPGLP-GPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGP 186

Query: 148 GGGSLASSSVAKSHSFFSLLKKNGRSENGKGEPVDASKAGGKQKRGLRGLFSGMRWHRKD 207
            G  L     A     F         +   GEP +   +G    RG  G   G      +
Sbjct: 187 RG--LPGPPGAPGPQGF---------QGPPGEPGEPGASGPMGPRGPPGP-PGKNGDDGE 234

Query: 208 KRAKAEAAEGRAPG--GGLILPGSLTASLECVKEETPRAAREPEEPSQDAPRDPAGEPAG 265
                   E   PG  G   LPG  TA L  +K     +  +  +     P  P GEP  
Sbjct: 235 AGKPGRPGERGPPGPQGARGLPG--TAGLPGMKGHRGFSGLDGAK-GDAGPAGPKGEPGS 291

Query: 266 GEEVPAPADRAPARSCREAEGLAHPGDTGARGEDAAGHRRAEPGPGEVRTAEDASRTGAV 325
             E  AP    P     E      PG  GARG D A      PGP     A      GAV
Sbjct: 292 PGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGP--TGPAGPPGFPGAV 349

Query: 326 PVKTVPLVD----SEGGSG--RAPAAPDPA-SVDPPSDPSADRICLMFSDVTSLKSFDSL 378
             K          SEG  G    P  P PA +  P  +P AD            K  +  
Sbjct: 350 GAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGAD-------GQPGAKGANGA 402

Query: 379 TGCGDIIADQEEEAGPSCDKHVPGPGKPALSKKNPGVVAYQGGGEEMASPDEVDDTYLQE 438
            G    IA      G        GPG P   K N G         E  +P    DT  + 
Sbjct: 403 PG----IAGAPGFPGARGPSGPQGPGGPPGPKGNSG---------EPGAPGSKGDTGAKG 449

Query: 439 FWDMLSQTEEQGPEPQEGAAKVAAALETKVVPETPKD-----TRCVEAAKDASSVKRRRL 493
               +      GP  +EG            +P  P +     +R    A   +  K    
Sbjct: 450 EPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAG 509

Query: 494 NR-IPIEPHPKEEPKHPEKEQQEGVPNSDEGYWDSTTPGPEEDSSSSGKKAGIPRDSYSG 552
            R  P    PK  P    +  + G+P +        +PGP+  +   G      R    G
Sbjct: 510 ERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPG 569

Query: 553 DALYDLYADPDGSPATLPGGKDNEETSSLSRLKPVSPGTI 592
                  A   G P   P G   E   +  R  P  PG +
Sbjct: 570 PPGARGQAGVMGFPG--PKGAAGEPGKAGERGVPGPPGAV 607



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 69/263 (26%), Positives = 81/263 (30%), Gaps = 39/263 (14%)

Query: 123 PRGGGDSGGGGGGRPNPGPPRAAGPGG-----------------GSLASSSVAKSHSFFS 165
           P+G     G  G R  PGPP A GP G                 G       A S  F  
Sbjct: 585 PKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQG 644

Query: 166 LLKKNG-RSENGK----GEPVDASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEGRA- 219
           L    G   E GK    G P D    G    RG RG F G R          +   G A 
Sbjct: 645 LPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERG-FPGER--------GVQGPPGPAG 695

Query: 220 PGGGLILPGSLTASLECVKEETPRAAREPEEPSQDAPRDPAGEPA----GGEEVPAPADR 275
           P G    PG+  A  +      P +   P        R  AG P      G+  P  AD 
Sbjct: 696 PRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADG 755

Query: 276 APAR-SCREAEG-LAHPGDTGARGEDAAGHRRAEPGPGEVRTAEDASRTGAVPVKTVPLV 333
           +P +   R   G +  PG  GA G+          GP   R A    R    P       
Sbjct: 756 SPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGA-PGDRGEPGPPGPAGFA 814

Query: 334 DSEGGSGRAPAAPDPASVDPPSD 356
              G  G+  A  +P       D
Sbjct: 815 GPPGADGQPGAKGEPGDAGAKGD 837



 Score = 35.4 bits (80), Expect = 0.17
 Identities = 84/371 (22%), Positives = 108/371 (29%), Gaps = 43/371 (11%)

Query: 90   GDGKSSGPTGLVRSRTHDGLAEVLVLESGRKEEPRGGGDSGGGGGGRPNPGPPRAAGPGG 149
            GD  + GP+G    R   G  E  V        PRG   + G  G + + G P A G  G
Sbjct: 665  GDLGAPGPSGARGERGFPG--ERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQG 722

Query: 150  GSLASSSVAKSHSFFSLLKKNGRSENGKGEPVDASKAGGKQKRGLRGLF----------- 198
                     +  +      K  R + G   P  A  + GK   G+RGL            
Sbjct: 723  APGLQGMPGERGAAGLPGPKGDRGDAG---PKGADGSPGKD--GVRGLTGPIGPPGPAGA 777

Query: 199  ---------SGMRWHRKDKRAKAEAAEGRAPG-GGLILPGSLTASLECVKEETPRAAREP 248
                     SG       + A  +  E   PG  G   P           E     A+  
Sbjct: 778  PGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGD 837

Query: 249  EEPSQDAPRDPAGEPAGGEEVPAPADRAPARSCREAEGLAHPGDTGARGEDAAGHRRAEP 308
              P    P  PAG P     V AP  +    S         PG  G  G          P
Sbjct: 838  AGPP--GPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPP 895

Query: 309  GP----------GEVRTAEDASRTGAVPVKTVPLVDSEGGSGRAPAAPDPASVDPPSDPS 358
            GP          G       A R G V     P    E GS  A           P   +
Sbjct: 896  GPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIA 955

Query: 359  ADRICLMFSDVTSLKSFDSLTG-CGDIIADQEEEAGPSCDKHVPGPGKPALSKKNPGVVA 417
              R  +        + F  L G  G+    ++  +G S ++  PGP  P      PG   
Sbjct: 956  GQRGVVGLPGQRGERGFPGLPGPSGE--PGKQGPSGASGERGPPGPMGPPGLAGPPGESG 1013

Query: 418  YQGGGEEMASP 428
             +G      SP
Sbjct: 1014 REGAPGAEGSP 1024



 Score = 32.0 bits (71), Expect = 1.9
 Identities = 77/319 (24%), Positives = 92/319 (28%), Gaps = 56/319 (17%)

Query: 6    SRGGGGAVSERGGAGASVGVCRRKAEAGAGTGTLAADMDLHCDCAAETPAAEP-PSGKIN 64
            +RG  G   E G  G +       A+   G      D     D     PA    P G I 
Sbjct: 795  ARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIG 854

Query: 65   KAAFKLFKKRKSGGTMPSIFGVKNKGDGKSSGPTGLVRSRTHDGLAEVLVLESGRKEEPR 124
                   K  +     P   G    G     GP G   +    G       E G+   PR
Sbjct: 855  NVGAPGAKGARGSAGPPGATGFP--GAAGRVGPPGPSGNAGPPGPPGPAGKEGGKG--PR 910

Query: 125  GGGDSGGGGGGRPNPGPPRAAGPGGGSLASSSVAKSHSFFSLLKKNGRSENGKGEPVDAS 184
            G     G  G    PGPP  AG  G   A                        G P    
Sbjct: 911  GETGPAGRPGEVGPPGPPGPAGEKGSPGADGPA--------------------GAPGTPG 950

Query: 185  KAGGKQKRGLRGLFSGMRWHR-----------KDKRAKAEAAEGRAPGGGLILPGSLTAS 233
              G   +RG+ GL  G R  R             K+  + A+  R P G +  PG     
Sbjct: 951  PQGIAGQRGVVGL-PGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPP 1009

Query: 234  LECVKEETPRAAREPEEPSQDAPRDPAGE--PAGGEEVPAPADRAPARSCREAEGLAHPG 291
             E  +E  P A   P        +   GE  PAG    P  A  AP            PG
Sbjct: 1010 GESGREGAPGAEGSPGRDGSPGAKGDRGETGPAG----PPGAPGAPGA----------PG 1055

Query: 292  DTGARGEDAAGHRRAEPGP 310
              G  G+      R E GP
Sbjct: 1056 PVGPAGKSGD---RGETGP 1071


>gi|27894378 chloride intracellular channel 6 [Homo sapiens]
          Length = 686

 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 117/496 (23%), Positives = 172/496 (34%), Gaps = 133/496 (26%)

Query: 118 GRKEEPRGGGDSGGGGGGRPNPGPPRAAGPGGGSLASSSVAKSHSFFSLLKKNGRSENGK 177
           G +E PRG       GGG P+ GP   A    G+                  +G +E  +
Sbjct: 46  GAEEAPRGAAAVKEAGGGGPDRGPEAEARGTRGA------------------HGETEAEE 87

Query: 178 GEPVDAS-KAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEGRAPGGGLILPGSLTASLEC 236
           G P  A    GG++  G                  A+  EG +PG G           E 
Sbjct: 88  GAPEGAEVPQGGEETSG------------------AQQVEGASPGRG----AQGEPRGEA 125

Query: 237 VKEETPRAAREPEEPSQDAPRDPAGEPAG--GEEVPAPAD-------RAPARSCREAEGL 287
            +E    AA E +E ++  P  P G  +G  G+ V A            PA    EAEG 
Sbjct: 126 QREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPLGDNIEAEGPAGDSVEAEG- 184

Query: 288 AHPGDTGARGEDAAGHRRAEPGP-GEVRTAEDASRTGAVPVKTVPLVDSEGGSGRAPAAP 346
              GD+    E  AG      GP G+   AE  +            VD+EG  G +  A 
Sbjct: 185 -RVGDS-VDAEGPAGDSVDAEGPLGDNIQAEGPAGDS---------VDAEGRVGDSVDAE 233

Query: 347 DPA--SVD---------PPSDPSADRICLMFSDVTSLKSFDSLTGCGDIIADQEEEAGPS 395
            PA  SVD            DP+ D +             ++    GD + + E  AG S
Sbjct: 234 GPAGDSVDAEGRVGDSVEAGDPAGDGV-------------EAGVPAGDSV-EAEGPAGDS 279

Query: 396 CDKHVPG------PGKPALSKKNPGVVAYQGGGEEMASPDEVDDTYLQEFWDMLSQTEEQ 449
            D   P        G+P   +   G ++ Q    E+A+ +    +  +  WD   + E  
Sbjct: 280 MDAEGPAGRARRVSGEP--QQSGDGSLSPQAEAIEVAAGESAGRSPGELAWDAAEEAEVP 337

Query: 450 GPEPQEGAAKVAAALETKVVPETPKDTRCVEAAKDASSVKRRRLNRIPIEPHPKEEPKHP 509
           G +  E AA              P D R  +A +D             +   P++EP   
Sbjct: 338 GVKGSEEAA--------------PGDAR-ADAGEDR------------VGDGPQQEPGED 370

Query: 510 EKEQQEGVPNSDEGYWDSTTPGPEEDSSSS------GKKAGIPRDSYSGDALYDLYADPD 563
           E+ ++     S EG  +    G EE+S  S       + A  P    S     +  A+  
Sbjct: 371 EERRE----RSPEGPREEEAAGGEEESPDSSPHGEASRGAAEPEAQLSNHLAEEGPAEGS 426

Query: 564 GSPATLPGGKDNEETS 579
           G  A + G +++ E S
Sbjct: 427 GEAARVNGRREDGEAS 442



 Score = 30.0 bits (66), Expect = 7.2
 Identities = 32/91 (35%), Positives = 37/91 (40%), Gaps = 27/91 (29%)

Query: 256 PRDPAGEPAGGEEVPAP-ADRAPARSCREAEGLAHPGDTGARGEDAAGHRRAEPGPGEVR 314
           P   A  P G  EVPAP A+R              PG+ GA G +A G   +E       
Sbjct: 7   PEGVAPGPQGPPEVPAPLAER--------------PGEPGAAGGEAEGPEGSE------- 45

Query: 315 TAEDASRTGAVPVKTVPLVDSEGGSGRAPAA 345
            AE+A R GA  VK        GG  R P A
Sbjct: 46  GAEEAPR-GAAAVKEA----GGGGPDRGPEA 71


>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2
           [Homo sapiens]
          Length = 2191

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 147/671 (21%), Positives = 225/671 (33%), Gaps = 126/671 (18%)

Query: 11  GAVSERGGAGASVGVCRRKAEAGAGTGTLAADMDLHCDCAAETPAAEPPSGKINKAAFKL 70
           G   E  G GA +G  +       G G  AA  + +    +  PA+  P G+        
Sbjct: 139 GGRYEHPGLGA-LGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCF--- 194

Query: 71  FKKRKSGGTMPSIFGVKNKGDGKSSGPTGLVR--SRTHDGLAEVLVLESGRKEEPR---- 124
               + GG      G+ +     ++G  G +     +H+G              P     
Sbjct: 195 ---DQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGG 251

Query: 125 --GGGDSGGGGGGRPNPGPPRAAGPGGGSLASSSVAKSHSFFSLLKKNGRSENGKGEPVD 182
             GGG  GGG GG    G   A G G G++A+++ A +            +  G G    
Sbjct: 252 GGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAA----------AAAGGGGGGGYG 301

Query: 183 ASKAGGKQKRGLRGLFSGMRWHRKDKRAK--AEAAEGRAPGGGLIL------PGSLTASL 234
            S AG       R    GM        A   ++AA G A GG          P   T +L
Sbjct: 302 GSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTL 361

Query: 235 ECVKEETPRAARE-----PEEPSQDAPRDPAGEPAGGEEVPAPADRAPARSCREAEGLAH 289
             +        R      PE  S  AP  P  +P    +  A A  A A   + A G+  
Sbjct: 362 NQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQP----QSQAAAAGAAAGGQQAAAGMGL 417

Query: 290 PGDTGARGEDAAGHRRAEPGPGEVRTAEDASRTGAVPVKTVPLVDSEGGSGRAPAAP-DP 348
             D GA+      +  A P     +     + +   P  T+         GR+  +P DP
Sbjct: 418 GKDMGAQ------YAAASPAWAAAQQRSHPAMSPGTPGPTM---------GRSQGSPMDP 462

Query: 349 ASVDPPSDPSADRICLMFSDVTSLKSFDSLTGCGDIIADQEEEAG--PSCDKHVPGPGK- 405
             +  P                       L G G     Q +++   P      PGP + 
Sbjct: 463 MVMKRP----------------------QLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRY 500

Query: 406 -PALSKKNPGVVAYQGGGEEMASPDEVDDTYLQEFWDMLSQTEEQGPEPQEGAAKVAAAL 464
              +  + PG +A   G +     D  D T+ + FW M  Q  +QG        +     
Sbjct: 501 PIGIQGRTPGAMA---GMQYPQQQDSGDATWKETFWLMPPQYGQQGVSGYCQQGQQPYYS 557

Query: 465 ETKVVPETPKDTRCV--------EAAKDASSVKRRRLNRIPIEPHPKEEPKHP-----EK 511
           +    P  P   + +        +  +D S       ++ P+ P    +P H      ++
Sbjct: 558 QQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAP---GKPNHEDLNLIQQ 614

Query: 512 EQQEGVPNSDEGYWDSTTPGPEEDSSSSGKKAGIPRDSYSGDALYDLYA--DPDGSP--A 567
           E+   +P+   G  D    G E   SS+   +G    S  GD      +   P  SP  +
Sbjct: 615 ERPSSLPDL-SGSIDDLPTGTEATLSSAVSASG--STSSQGDQSNPAQSPFSPHASPHLS 671

Query: 568 TLPGGKDNEET-----SSLSRLKPVSPGTITCPLRTPGSLLKDSKIPISIKHLTNLPSSH 622
           ++PGG           S+ SR  P+SP +I      PG     S++P       +  SSH
Sbjct: 672 SIPGGPSPSPVGSPVGSNQSRSGPISPASI------PG-----SQMPPQPPGSQSESSSH 720

Query: 623 PVVHQQPSRSE 633
           P + Q P   E
Sbjct: 721 PALSQSPMPQE 731



 Score = 29.6 bits (65), Expect = 9.4
 Identities = 31/188 (16%), Positives = 65/188 (34%), Gaps = 9/188 (4%)

Query: 396  CDKHVPGPGKPALSKKNPGVVAYQGGGEEMASPDEVDDTYLQEFWDMLSQTEEQGPEPQE 455
            C K + G  +   +KK   +      G   ++   +   Y+Q  +    + E     P E
Sbjct: 1048 CVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQYLFAFECKIERGEEPPPE 1107

Query: 456  GAAKVAAALETKVVPETPKDTRCVEAAKDASSVKRRRLNRIPIE---------PHPKEEP 506
              +      + K+ P +P ++  ++  +   S     +  +P +         PH +  P
Sbjct: 1108 VFSTGDTKKQPKLQPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTP 1167

Query: 507  KHPEKEQQEGVPNSDEGYWDSTTPGPEEDSSSSGKKAGIPRDSYSGDALYDLYADPDGSP 566
                +     V +      DS+ P     + ++  + G+      G   Y+   DP G  
Sbjct: 1168 MQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGM 1227

Query: 567  ATLPGGKD 574
              +PG  +
Sbjct: 1228 RKVPGSSE 1235


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 88/334 (26%), Positives = 109/334 (32%), Gaps = 67/334 (20%)

Query: 126 GGDSGGGGGGRPN----PGPPRAAGPGGGSLASSSVAKSHSFFSLLKKNG---------- 171
           G D   G  GRP     PGPP   GP G  +      K H  F    +NG          
Sbjct: 228 GKDGESGRPGRPGERGLPGPPGIKGPAG--IPGFPGMKGHRGFD--GRNGEKGETGAPGL 283

Query: 172 RSENG----KGEPVDASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEGRAPG--GGLI 225
           + ENG     G P      G   +RG  GL  G    R +  A+    +   PG  G   
Sbjct: 284 KGENGLPGENGAPGPMGPRGAPGERGRPGL-PGAAGARGNDGARGSDGQPGPPGPPGTAG 342

Query: 226 LPGSLTASLECVKEETPRAAREPEEPSQDAPRDPAG------------EPAG-GEEVPAP 272
            PGS  A  E     +P +   P +  +  P+  AG             P G GE  PA 
Sbjct: 343 FPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAG 402

Query: 273 ADRAPA-RSCREAEGLAH----PGDTGARGEDAAGHRRAEPGPGEVRTAEDASRTGAVPV 327
              AP     R   G A     PG  G  GE      + EPGP   R        G   +
Sbjct: 403 IPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGER--------GEAGI 454

Query: 328 KTVPLVDSEGGSGRAPAAPDPASVDPPSDPSADRICLMFSDVTSLKSFDSLTGCGDIIAD 387
             VP    E G   +P  P    +     P A       +       F    G   I   
Sbjct: 455 PGVPGAKGEDGKDGSPGEPGANGL-----PGA-------AGERGAPGFRGPAGPNGIPG- 501

Query: 388 QEEEAGPSCDKHVPGPGKPALSKKNPGVVAYQGG 421
              E GP+ ++  PGP  P  +   PG     GG
Sbjct: 502 ---EKGPAGERGAPGPAGPRGAAGEPGRDGVPGG 532



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 116/478 (24%), Positives = 147/478 (30%), Gaps = 52/478 (10%)

Query: 125 GGGDSGGGGGGRPNPGPPRAAGPGGGSLASSSVAKSHSFFSLLKKNGRSENGKGEPVDAS 184
           G   S G  G +  PG P  AGP G      ++  S        K+G S    G P +  
Sbjct: 189 GHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPS----GPAGKDGES-GRPGRPGERG 243

Query: 185 KAGGKQKRGLRGL--FSGMRWHRKDKRAKAEAAEGRAPG--GGLILPGSLTASLECVKEE 240
             G    +G  G+  F GM+ HR       E  E  APG  G   LPG   A        
Sbjct: 244 LPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRG 303

Query: 241 TPRAAREPEEPSQDAPR--DPAGEPAGGEEVPAPADRAPARSCREAEGLAHPGDTGARGE 298
            P     P  P     R  D A    G    P P   A       A+G    G  G+ G 
Sbjct: 304 APGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKG--EVGPAGSPGS 361

Query: 299 DAAGHRRAEPGPGEVRTAEDASRTGAVPVKTVPLVDSEGGSGRAPAAPDPASVDPPSDPS 358
           + A  +R EPGP     A+     G   +   P    E G    P AP       P  P+
Sbjct: 362 NGAPGQRGEPGPQGHAGAQ--GPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPA 419

Query: 359 ADRICLMFSDVTSLKSFDSLTGCGDIIADQEEEAGPSCDKHVPGPGKPALSKKNPGVVAY 418
                   +    L+      G G        E G +  K  PGP         PGV   
Sbjct: 420 G------ANGAPGLRG-----GAG--------EPGKNGAKGEPGPRGERGEAGIPGVPGA 460

Query: 419 QGGGEEMASPDEVDDTYLQEFWDMLSQTEEQGPEPQEG--AAKVAAALETKVVPETPKDT 476
           +G   +  SP E     L            +GP    G    K  A       P  P+  
Sbjct: 461 KGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGA 520

Query: 477 RCVEAAKDASSVKRRRLNRIPIEPHPKEEPKHPEKEQQEGVPNSDEGYWDSTTPGPEEDS 536
              E  +D           +P  P  +  P  P     +G P       +S  PGP   S
Sbjct: 521 -AGEPGRDG----------VPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPS 569

Query: 537 SSSGKKAGI----PRDSYSGDALYDLYADPDGSPATLPGGKDNEETSSLSRLKPVSPG 590
              G+   +    P+ +            P G     P GK N ET       P  PG
Sbjct: 570 GPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGK-NGETGPQGPPGPTGPG 626



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 95/379 (25%), Positives = 119/379 (31%), Gaps = 68/379 (17%)

Query: 11   GAVSERGGAGASVGVCRRKAEAGAGTGTLAADMDLHCDCAAETPAAEPPSGKINKAAFKL 70
            G   ERGG G S G    K E G G G          D          P+G I       
Sbjct: 726  GMPGERGGLG-SPGPKGDKGEPG-GPGA---------DGVPGKDGPRGPTGPIGPPGPAG 774

Query: 71   FKKRKSGGTMPSIFGVKN-KGDGKSSGPTGLVRSRTHDGLAEVLVLESGRKEEPRGGGDS 129
                K  G  P + G+   +G     G TG        G         G+  EP G G+ 
Sbjct: 775  QPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAP-------GQNGEPGGKGER 827

Query: 130  GGGGGGRPNPGPPRAAGPGGGSLASSSVAKSHSFFSLLKKNGRSENGKGEPVDASKAGGK 189
            G  G  +   GPP  AGP GGS  +                   +  +G P     AG  
Sbjct: 828  GAPGE-KGEGGPPGVAGPPGGSGPAGPPGPQ-----------GVKGERGSPGGPGAAGFP 875

Query: 190  QKRGLRGLFSGMRWHRKDKRAKAEAAEGRAPG--GGLILPGSLTASLECVKEETPRA-AR 246
              RGL G   G   +           +   PG  G    PGS   S        P+  A 
Sbjct: 876  GARGLPGP-PGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVS-------GPKGDAG 927

Query: 247  EPEEPSQDAPRDPAGEP--------AGGEEVPAPADRAPARSCREAEGLAHPGDTGARGE 298
            +P E      + P G P         G   +  P      R     +G+   G++G  G 
Sbjct: 928  QPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGV--KGESGKPGA 985

Query: 299  DAAGHRRAEPG----PGEVRTAEDASRTGAVPVKTVPLVD-SEGGSG-----------RA 342
            +     R  PG    PG   TA +  R G      +P  D S GG G            A
Sbjct: 986  NGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGA 1045

Query: 343  PAAPDPASVDPPSDPSADR 361
            P  P P     P+  S DR
Sbjct: 1046 PGHPGPPGPVGPAGKSGDR 1064



 Score = 38.5 bits (88), Expect = 0.020
 Identities = 61/246 (24%), Positives = 76/246 (30%), Gaps = 53/246 (21%)

Query: 123 PRGGGDSGGGGGGRPNPGPPRAAG----PGGGSLASSSVAKSHSFFSLLKKNGRSENGKG 178
           P G   S G  G R  PGP   AG    PG   +  S   K     + +         +G
Sbjct: 355 PAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARG 414

Query: 179 EPVDASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEGRAPGGGLILPGSLTASLECVK 238
            P  A   G    RG  G   G    + +   + E  E   PG    +PG+         
Sbjct: 415 PPGPAGANGAPGLRGGAG-EPGKNGAKGEPGPRGERGEAGIPG----VPGA--------- 460

Query: 239 EETPRAAREPEEPSQDAPRDPA--GEPAGGEEVPAPADRAPARSCREAEGLAHPGDTGAR 296
                   + E+    +P +P   G P    E  AP  R PA            G  G  
Sbjct: 461 --------KGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPA------------GPNGIP 500

Query: 297 GEDAAGHRRAEPGPGEVRTAEDASRTGAVPVKTVPLVDSEGGSGR--APAAP-DPASVDP 353
           GE      R  PGP   R A        VP          GG G    P +P  P S   
Sbjct: 501 GEKGPAGERGAPGPAGPRGAAGEPGRDGVP----------GGPGMRGMPGSPGGPGSDGK 550

Query: 354 PSDPSA 359
           P  P +
Sbjct: 551 PGPPGS 556



 Score = 38.1 bits (87), Expect = 0.027
 Identities = 91/364 (25%), Positives = 116/364 (31%), Gaps = 45/364 (12%)

Query: 7   RGGGGAVSERGGAGASVGVCRRKAEAGAGTGTLAADMDLHCDCAAETPAAEPPSGKINKA 66
           RGG G   + G  G   G    + EAG   G   A  +   D +   P A    G   + 
Sbjct: 428 RGGAGEPGKNGAKGEP-GPRGERGEAGI-PGVPGAKGEDGKDGSPGEPGANGLPGAAGER 485

Query: 67  AFKLFKKRKSGGTMPSIFG-VKNKGDGKSSGPTGLVRSRTHDGLAEVLVLESGRKEEPRG 125
               F+       +P   G    +G    +GP G       DG+     +  G    P G
Sbjct: 486 GAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMR-GMPGSPGG 544

Query: 126 GGDSG-----GGGGGRPNPGPPRAAGP-GGGSLASSSVAKSHSFFSLLKKNGRSENGKGE 179
            G  G     G  G    PGPP  +GP G   +      K +       KNG    G G 
Sbjct: 545 PGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGND--GAPGKNG-ERGGPGG 601

Query: 180 PVDASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEGRAPGGGLILPGSLTASLECVKE 239
           P      G   + G +G   G      DK           P G   LPG+          
Sbjct: 602 PGPQGPPGKNGETGPQGP-PGPTGPGGDKGDTGPP----GPQGLQGLPGT---------G 647

Query: 240 ETPRAAREPEEPSQDAPRDPAGEPAGGEEVPAPADRAPARSCREAEGLAHPGDTGARGED 299
             P    +P EP         G P G  +  AP +R P        GLA  G  G RG  
Sbjct: 648 GPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGP-------PGLA--GAPGLRG-- 696

Query: 300 AAGHRRAEPGPGEVRTAEDASRTGAVPVKTVPLVDSEGGSGRAPAAPDP-ASVDPPSDPS 358
            AG    E G G           G   ++ +P     GG G    +P P      P  P 
Sbjct: 697 GAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMP--GERGGLG----SPGPKGDKGEPGGPG 750

Query: 359 ADRI 362
           AD +
Sbjct: 751 ADGV 754



 Score = 37.4 bits (85), Expect = 0.045
 Identities = 61/256 (23%), Positives = 81/256 (31%), Gaps = 38/256 (14%)

Query: 123  PRGGGDSGGGGGGRPNPGPPRAAGPGG--GSLASSSVAKSHSFFSLLKKNG----RSENG 176
            P+G     G  G     GPP A GP G  G   +  +A            G    + E+G
Sbjct: 922  PKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESG 981

Query: 177  K-GEPVDASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEGRAPGGGLILPGSLTASLE 235
            K G    + + G    +GL GL        +D    ++   GR        PG      E
Sbjct: 982  KPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGS-----PGGKGDRGE 1036

Query: 236  CVKEETPRAAREPEEPS------------QDAPRDPAGEPAGGEEVPAPADRAPARSCRE 283
                  P A   P  P             +  P  PAG P       AP  + P      
Sbjct: 1037 NGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPR----- 1091

Query: 284  AEGLAHPGDTGARG-EDAAGHRRAEPGPGEVRTAEDASRTGAV----PVKTVPLVDSEGG 338
                   G+TG RG     GHR     PG   +   A + GA+    P      V   G 
Sbjct: 1092 ----GDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGP 1147

Query: 339  SGRAPAAPDPASVDPP 354
             G+   +  P  + PP
Sbjct: 1148 PGKDGTSGHPGPIGPP 1163



 Score = 35.8 bits (81), Expect = 0.13
 Identities = 62/267 (23%), Positives = 79/267 (29%), Gaps = 35/267 (13%)

Query: 118  GRKEEPRGGGDSG--------GGGGGRPNPGPPRAAGPGGGS----LASSSVAKSHSFFS 165
            G +  P G G +G        G  G   NPGPP  +G  G       A ++ A      S
Sbjct: 861  GERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVS 920

Query: 166  LLKKNGRSENGKGEPVDASKAGGKQKRGLRGLFS--------GMRWHRKDKRAKAEAAEG 217
              K +      KG P      G     G+ G+          GM   R     +    E 
Sbjct: 921  GPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGES 980

Query: 218  RAPGGGLIL-----PGSLTASLECVKEETPRAAREPEEPSQDAPRDPAGEPAGGEEVPAP 272
              PG   +      PG          +  P  A    EP +D      G P         
Sbjct: 981  GKPGANGLSGERGPPGP---------QGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGK 1031

Query: 273  ADRAPARSCREAEGLAHPGDTGARGEDAAGHRRAEPGPGEVRTAEDASRTGAVPVKTVPL 332
             DR    S        HPG  G  G       R E GP     A   + +   P    P 
Sbjct: 1032 GDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPR 1091

Query: 333  VDSEGGSGRAPAAPDPASVDPPSDPSA 359
             D +G +G   AA        P +P A
Sbjct: 1092 GD-KGETGERGAAGIKGHRGFPGNPGA 1117



 Score = 35.4 bits (80), Expect = 0.17
 Identities = 63/250 (25%), Positives = 75/250 (30%), Gaps = 50/250 (20%)

Query: 123 PRGGGDSGGGGGGRPNPGPPRAAGPGGGSLASSSVAKSHSFFSLLKKNGRSENGKGEPVD 182
           P+G   + G  G R  PG P   GP G                   KNG  E G   P  
Sbjct: 583 PKGNDGAPGKNGERGGPGGPGPQGPPG-------------------KNG--ETGPQGPPG 621

Query: 183 ASKAGGKQ-------KRGLRGLFS-----GMRWHRKDKRAKAEAAEGRAPGGGLILPGSL 230
            +  GG +        +GL+GL       G      +   K +A    APGG     G  
Sbjct: 622 PTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGG----KGDA 677

Query: 231 TASLECVKEETPRAAREPEEPSQDAPRDP-AGEPAGGEEVPAPADRAPARSCREAE--GL 287
            A  E      P  A  P       P  P  G+ A G   P  A   P       E  GL
Sbjct: 678 GAPGE---RGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGL 734

Query: 288 AHPGDTGARGEDAAGHRRAEPGPGEVRTAEDASRTGAVPVKTVPLVDSEGGSGRAPAAPD 347
             PG  G +GE         PG       +D  R    P+         G  G   A   
Sbjct: 735 GSPGPKGDKGEPGGPGADGVPG-------KDGPRGPTGPIGPPGPAGQPGDKGEGGAPGL 787

Query: 348 PASVDPPSDP 357
           P    P   P
Sbjct: 788 PGIAGPRGSP 797



 Score = 33.9 bits (76), Expect = 0.50
 Identities = 102/450 (22%), Positives = 128/450 (28%), Gaps = 87/450 (19%)

Query: 124 RGGGDSGGGGGGRPNPGPPRAAGPGGGSLASSSVAKSHSFFSLLKKNGRSENGKGEPVDA 183
           RGG    G  G +  PGP    G  G  +     AK         ++G+ +   GEP   
Sbjct: 428 RGGAGEPGKNGAKGEPGPRGERGEAG--IPGVPGAKG--------EDGK-DGSPGEPGAN 476

Query: 184 SKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEGRAPGGGLILPGSLTASLECVKEETPR 243
              G   +RG  G F G          K  A E  APG      G   A+ E  ++  P 
Sbjct: 477 GLPGAAGERGAPG-FRGPAGPNGIPGEKGPAGERGAPGPA----GPRGAAGEPGRDGVPG 531

Query: 244 AARE---PEEPSQDAPRDPAGEPAGGEEVPAPADRAPARSCREAEGLAHPGDTGARGEDA 300
                  P  P         G P    E   P    P+    +   +  PG  G  G   
Sbjct: 532 GPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPG 591

Query: 301 AGHRRAEP-GPGEVRTAEDASRTGAVPVKTVPLVDSEGGSGRAPAAPDPASVDPPSDPSA 359
               R  P GPG          TG            +G  G      D     PP     
Sbjct: 592 KNGERGGPGGPGPQGPPGKNGETG-----------PQGPPGPTGPGGDKGDTGPPGP--- 637

Query: 360 DRICLMFSDVTSLKSFDSLTGCGDIIADQEEEAGPSCDKHVPGPGKPALSKKNPGVVAYQ 419
                        +    L G G          GP  +   PG   P   K + G     
Sbjct: 638 -------------QGLQGLPGTG----------GPPGENGKPGEPGP---KGDAGAPGAP 671

Query: 420 GGGEEMASPDEVDDTYLQEFWDMLSQTEEQGPEPQEGAAKVAAALETKVVPETPKDTRCV 479
           GG  +  +P E     L     +       GPE  +GAA           P  P      
Sbjct: 672 GGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAG----------PPGPPGAAGT 721

Query: 480 EAAKDASSVKRRRLNRIPIEPHPKEEPKHPEKEQQEGVPNSDEGYWDSTTPGPEEDSSSS 539
              +     +R  L      P PK +   P     +GVP  D         GP   +   
Sbjct: 722 PGLQGMPG-ERGGLG----SPGPKGDKGEPGGPGADGVPGKD---------GPRGPTGPI 767

Query: 540 GK--KAGIPRDSYSGDAL-YDLYADPDGSP 566
           G    AG P D   G A      A P GSP
Sbjct: 768 GPPGPAGQPGDKGEGGAPGLPGIAGPRGSP 797



 Score = 30.4 bits (67), Expect = 5.5
 Identities = 23/70 (32%), Positives = 30/70 (42%), Gaps = 2/70 (2%)

Query: 89   KGDGKSSGPTGLVRSRTHDGLAEVLVLESGRKEEPRGGGDSGGGGGGRPNPGPPRAAGPG 148
            +G    SGP G   +  H G          R E  RG   S G  G    PGPP A GP 
Sbjct: 1139 RGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGE--RGSEGSPGHPGQPGPPGPPGAPGPC 1196

Query: 149  GGSLASSSVA 158
             G + ++++A
Sbjct: 1197 CGGVGAAAIA 1206


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 123/457 (26%), Positives = 157/457 (34%), Gaps = 133/457 (29%)

Query: 7    RGGGGAVSERGGAG--ASVGVCRRKAEAG----AGTGTLAADMDLHCDCAAETPAAEPPS 60
            RG  GA+  +G  G    +G    K E G    AG+  L           A  P A+ P 
Sbjct: 1470 RGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPG--------VAGRPGAKGPE 1521

Query: 61   GKINKAAFKLFKKRKSGGTMPSIFGVK------NKGDGKSSGP---TGLVRSRTHDGLAE 111
            G       +  K        P++ G         KGD   +GP   TG+   R   GL  
Sbjct: 1522 GPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGL-- 1579

Query: 112  VLVLESGRKEEP----------RGG--GDSGGGG--GGRPNPGPPRAAGPGGGSLASSSV 157
            VL  + G K +P          R G  GDSG  G  G    PGPP   GP G        
Sbjct: 1580 VLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRG-------- 1631

Query: 158  AKSHSFFSLLKKNGR--SENGKGEPVDASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAA 215
                       ++G    +  +G P D    G   +RGLRG   G+R    +K  + +  
Sbjct: 1632 -----------RDGEVGEKGDEGPPGDPGLPGKAGERGLRGA-PGVRGPVGEKGDQGDPG 1679

Query: 216  E-GR-------APGGGLILPGSLTASLECVKEETPRAAREPEEP---SQDAPRDPAGEPA 264
            E GR        P G    PG        V  +T   ARE  EP    Q+ PR P G+P 
Sbjct: 1680 EDGRNGSPGSSGPKGDRGEPGPPGPPGRLV--DTGPGAREKGEPGDRGQEGPRGPKGDPG 1737

Query: 265  GGEEVP-APADRAPARSCREAEGLAHP----GDTGARGEDAAGHRRAEPGPGEVRTAEDA 319
                +P AP +R         EG   P    GD G RG       R  PG  + R+  D 
Sbjct: 1738 ----LPGAPGERG-------IEGFRGPPGPQGDPGVRGPAGEKGDRGPPGL-DGRSGLDG 1785

Query: 320  SRTGAVPVKTVPLVDSEGGSGRAPAAPDPASVDPPSDPSADRICLMFSDVTSLKSFDSLT 379
                A P          G +G A  A DP                           D L 
Sbjct: 1786 KPGAAGP---------SGPNGAAGKAGDPGR-------------------------DGLP 1811

Query: 380  GCGDIIADQEEEAGPSCDKHVPG----PGKPALSKKN 412
            G    +  ++   GPS    +PG     GKP L+ KN
Sbjct: 1812 G----LRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKN 1844



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 116/478 (24%), Positives = 148/478 (30%), Gaps = 103/478 (21%)

Query: 118  GRKEEPRGGGDSG--GGGGGRPNPG-PPRAAGPGGGSLASSSVAKSHSFFSLLKKNGRSE 174
            G+K EP   G+ G  G  G   +PG P R   PG      S+ AK    F        ++
Sbjct: 1254 GQKGEP---GEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFP------GAD 1304

Query: 175  NGKGEPVDASKAGGKQKRGLRGL--FSGMRWHRKDKRAKAEAAEGRAPGGGLILPGSLTA 232
               G P  A   G     GL+G     G R    ++  +    E  APG           
Sbjct: 1305 GRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPG----------- 1353

Query: 233  SLECVKEETPRAAREPEEPSQDAPRDPAGEPAGGEEVPAPADRAPARSCREAEGLAHPGD 292
              + +  E P       +P    P  P G P G      P  R P        G A  GD
Sbjct: 1354 --QVIGGEGPGLPGRKGDPGPSGPPGPRG-PLGD-----PGPRGPP----GLPGTAMKGD 1401

Query: 293  TGARGEDAAGHRRAEPGPGEVRTAEDASRTGAVPVKTVP------------LVDSEGGSG 340
             G RGE      R  PGPGE   A        +P    P              DSE G+ 
Sbjct: 1402 KGDRGE------RGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAP 1455

Query: 341  RAPAAP-DPASVDPPSDPSADRICLMFSDVTSLKSFDSLTGCGDIIADQEEEAGPSCDKH 399
              P  P  P    P   P A             + F    G          EAG   +K 
Sbjct: 1456 GLPGQPGSPGEQGPRGPPGA-------IGPKGDRGFPGPLG----------EAG---EKG 1495

Query: 400  VPGPGKPALSKKNPGVVAYQGGGEEMASPDEVDDTYLQEFWDMLSQTEEQGPEPQEGAAK 459
              GP  PA S+  PGV    G       P                 T  QG + + G   
Sbjct: 1496 ERGPPGPAGSRGLPGVAGRPGAKGPEGPP---------------GPTGRQGEKGEPGRPG 1540

Query: 460  VAAALETKVV-PETPKDTRCVEAAKDASSVKRRRLNR---IPIEPHPKEEP--KHPEKEQ 513
              A +   V  P+  K        + A+ V+  R      +P +P PK +P  + P    
Sbjct: 1541 DPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLT 1600

Query: 514  QEGVPNSDEGYWDSTTPGPEEDSSSSGKKAGIPRDSYSGDALYDLYADPDGSPATLPG 571
                P  D G      PG + D    G    +      G+        P G P  LPG
Sbjct: 1601 GRAGPPGDSG-----PPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPG-LPG 1652



 Score = 36.2 bits (82), Expect = 0.10
 Identities = 65/257 (25%), Positives = 83/257 (32%), Gaps = 34/257 (13%)

Query: 118  GRKEEPRGGGDSG-GGGGGRPN-------PGPPRAAGPGGGSLASSSVAKSHSFFSLLKK 169
            G   +P   G+ G  G  GR         PGPP + GP G S       K      L   
Sbjct: 2413 GEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGD--KGDPGVGLPGP 2470

Query: 170  NGRSENGKGEPVDASKAGGKQKRGLRGLFS--GMRWHRKDKRAKAEAAEGRAPGGGLIL- 226
             G     +GEP    + G   + G RGL    G R  R +K     A      G   ++ 
Sbjct: 2471 RGE----RGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVIL 2526

Query: 227  --PGSLTASLECVKEETPRAAREPEEPSQD----APRDPAGEPAGGEEVPAPADRAPARS 280
              PG   A  + + E  PR     + P  D      +   GEP        P  R     
Sbjct: 2527 GPPGPRGAKGD-MGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGP 2585

Query: 281  CREAEGLAHPGDTGARGEDAAGHRRAEPGPGEVRTAEDASRTGAVPVKTVPLVDSEGGSG 340
              +      PGD G+ G+D     R E   G+V         G   VK    +D E G  
Sbjct: 2586 QGQPGAAGIPGDPGSPGKDGVPGIRGE--KGDVGFMGPRGLKGERGVKGACGLDGEKG-- 2641

Query: 341  RAPAAPDPASVDPPSDP 357
                  D     PP  P
Sbjct: 2642 ------DKGEAGPPGRP 2652



 Score = 34.3 bits (77), Expect = 0.38
 Identities = 67/277 (24%), Positives = 94/277 (33%), Gaps = 43/277 (15%)

Query: 120  KEEPRGGGDSGGGGGGRPNPGPPRAAGPGGGSLASSSVAKSHSFFSLLKKNGRSENGKGE 179
            ++ PRG   + G  G R  PGP   AG   G       A S     +  + G ++  +G 
Sbjct: 1466 EQGPRGPPGAIGPKGDRGFPGPLGEAGE-KGERGPPGPAGSRGLPGVAGRPG-AKGPEGP 1523

Query: 180  PVDASKAGGKQKRGLRG-------LFSGMRWHRKDKRAK----AEAAEGRAPGGGLILPG 228
            P    + G K + G  G         +G +  + D        A   +G     GL+LPG
Sbjct: 1524 PGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPG 1583

Query: 229  --------------SLTASLECVKEETPRAAR-EPEEPSQDAPRDPAGEPA----GGEEV 269
                           LT       +  P   + +P  P    P  P G        G+E 
Sbjct: 1584 DPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEG 1643

Query: 270  PAPAD-----RAPARSCREAEGLAHP-GDTGARGEDAAGHRRAEPGPGEVRTAEDASRTG 323
            P P D     +A  R  R A G+  P G+ G +G+     R   PG    +   D    G
Sbjct: 1644 P-PGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPK--GDRGEPG 1700

Query: 324  AVPVKTVPLVDSEGGSGRAPAAPDPASVDPPSDPSAD 360
              P     LVD+ G   R    P     + P  P  D
Sbjct: 1701 P-PGPPGRLVDT-GPGAREKGEPGDRGQEGPRGPKGD 1735



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 56/206 (27%), Positives = 66/206 (32%), Gaps = 38/206 (18%)

Query: 123  PRGGGDSGGGGGGRPNPGPPRAAGPGGGSLASSSVAKSHSFFSLLKKNGRSENGKGEPVD 182
            PRG     GG G    PG P  AGP G    S                 + E G+  P  
Sbjct: 2172 PRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGL---------------KGEPGETGPPG 2216

Query: 183  ASKAGGKQKRGLRGL--FSGMRWHRKDKRAKAEAAEGRAPGGGLILPGSLTASLECVKEE 240
                G     GL G    SG+   +       +  E   PG     PG   AS +     
Sbjct: 2217 RGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGA----PGRDGASGKDGDRG 2272

Query: 241  TPRAAREPEEPSQDAPRDPAGEP----AGGEEV---PAPADRAPARSCREAEGLAHPGD- 292
            +P     P  P    P  P GEP    A G+ V   P       A      + +  PG  
Sbjct: 2273 SPGV---PGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAK 2329

Query: 293  -----TGARGEDAAGHRRAEPG-PGE 312
                  G RGE     R  EPG PGE
Sbjct: 2330 GDRGLPGPRGEKGEAGRAGEPGDPGE 2355


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 91/340 (26%), Positives = 114/340 (33%), Gaps = 52/340 (15%)

Query: 118  GRKEEPRGGGDSGGGGG-GRPNP----GPPRAAGPGG----GSLASSSVAKSHSFFSLLK 168
            G + EP   G  G  G  G P P    GPP   GP G      L  +     H       
Sbjct: 694  GPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHP-----G 748

Query: 169  KNGRS--ENGKGEPVDASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEGRAPG--GGL 224
            K G+S  +   G P      G    RG++G   G+R     K +K E  E   PG  G +
Sbjct: 749  KEGQSGEKGALGPPGPQGPIGYPGPRGVKGA-DGVRGL---KGSKGEKGEDGFPGFKGDM 804

Query: 225  ILPGSLTASLECVKEETPRAAREPEEPSQDAPRDPAGEPA----GGEEVPAPADRAPARS 280
             L G        V +  PR    PE P   A   P G+P      GE+        P   
Sbjct: 805  GLKGDRGE----VGQIGPRGEDGPEGPKGRA--GPTGDPGPSGQAGEKGKLGVPGLPGYP 858

Query: 281  CREAE--GLAHPGDTGARGEDAAGHRRAEPGPGEVR--TAEDASRTGAVPVKTVPLVDSE 336
             R+        PG  GA GE  A     +PGP   R  T    SR    P        + 
Sbjct: 859  GRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTS 918

Query: 337  GGSG-------RAPAAPD-----PASVDPPSDPSADRICLMFSD--VTSLKSFDSLTGCG 382
            GG G       R P  P      P    PP  P  D +         T  +      G G
Sbjct: 919  GGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPG 978

Query: 383  DIIADQEE--EAGPSCDKHVPGPGKPALSKKNPGVVAYQG 420
             ++  Q    E GP  ++  PGP  P   +  PG    +G
Sbjct: 979  GVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEG 1018



 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 80/324 (24%), Positives = 107/324 (33%), Gaps = 44/324 (13%)

Query: 123  PRGGGDSGGGGGGRPNPGPPRAAGPGGGSLASSSVAKSHSFFSLLKKNGRSENGK----G 178
            P G     G  G    PGPP   GP G + A        S  S+     + E G+    G
Sbjct: 1217 PPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPG 1276

Query: 179  EPVDASKAGGKQKRGLRGLFS--------GMRWHRKDKRAKAEAAEGRAPGGGLILPGSL 230
             P +A   G K +RG +G           G +    D   K        PG     PG  
Sbjct: 1277 PPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGD----PGPP 1332

Query: 231  TASLECVKEETPRAAREPEEPSQDAPRDPAGEPAGGEEVPAPADRAPARSCREAEGLAHP 290
                   ++       E  +P Q  P  P+GE       P P  +        AEG    
Sbjct: 1333 GEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAG----PPGPPGKRGPPGAAGAEG--RQ 1386

Query: 291  GDTGARGEDAAGHRRAEPGPGEVRTAEDASRTGAVPVKTVP-LVDSEGGSGRAPAAPDPA 349
            G+ GA+GE  A     + GP  V     A + G   ++ +P  V  +G  G A     P 
Sbjct: 1387 GEKGAKGEAGAEGPPGKTGP--VGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPG 1444

Query: 350  SVDPPSDPSADRICLMFSDVTSL--KSFDSLTGCGDIIADQEEEA-----------GPSC 396
             + PP  P       +  D  S   K    L G      +Q E+            G   
Sbjct: 1445 PMGPPGLPG------LKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKG 1498

Query: 397  DKHVPGPGKPALSKKNPGVVAYQG 420
            D  +PGP  P      PG+   QG
Sbjct: 1499 DGGIPGPAGPLGPPGPPGLPGPQG 1522



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 52/199 (26%), Positives = 68/199 (34%), Gaps = 29/199 (14%)

Query: 123  PRGGGDSGGGGGGRPNPGPPRAAGPGGGSLASSSVAKSHSFFSLLKKNGRSENGKGEPVD 182
            P+G     G  G R +PGPP   GP G      +  K              E  KG+P  
Sbjct: 983  PQGPTGETGPIGERGHPGPP---GPPGEQGLPGAAGK--------------EGAKGDPGP 1025

Query: 183  ASKAGGKQKRGLRGLFSGMRWHRKDKRAKA-EAAEG-RAPGGGLILPGSLTASLECVK-- 238
               +G     GLRG F G R     + A   +  EG + P G +  PG   ++       
Sbjct: 1026 QGISGKDGPAGLRG-FPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIG 1084

Query: 239  -------EETPRAAREPEEPSQDAPRDPAGEPAGGEEVPAPADRAPARSCREAEGLAHPG 291
                   +  P  A E   P +  P+ PAG       V  P    PA S  E       G
Sbjct: 1085 LPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIG 1144

Query: 292  DTGARGEDAAGHRRAEPGP 310
            + G +G          PGP
Sbjct: 1145 EPGQKGSKGDKGENGPPGP 1163



 Score = 33.5 bits (75), Expect = 0.65
 Identities = 72/276 (26%), Positives = 86/276 (31%), Gaps = 74/276 (26%)

Query: 96  GPTGLVRSRTHDGLAEVLVLESGRKEEPRGGGDSGGGGG-GRPNP-GPPRAAGPGG---- 149
           GP G    +   GLA  L    G    P   G SG  G  G P P GP    GP G    
Sbjct: 721 GPPGEKGPQGKPGLAG-LPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGA 779

Query: 150 ---GSLASSSVAKSHSFFSLLK-----KNGRSENGK-------------------GEPVD 182
                L  S   K    F   K     K  R E G+                   G+P  
Sbjct: 780 DGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGP 839

Query: 183 ASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEGR-APGGGLILPGSLTASLE-----C 236
           + +AG K K G+ GL                   GR  P G    PG   A+ E      
Sbjct: 840 SGQAGEKGKLGVPGL---------------PGYPGRQGPKGSTGFPGFPGANGEKGARGV 884

Query: 237 VKEETPRAAREPEEP-SQDAPRDPAGEP-----AGGEEVPAPADRAPARSCREAEGLAHP 290
             +  PR  R P  P      R P G+P     +GG+  P P      +  +   G   P
Sbjct: 885 AGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGP 944

Query: 291 -------------GDTGARGEDAAGHRRAEPGPGEV 313
                        G  G RGE     +   PGPG V
Sbjct: 945 KGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGV 980



 Score = 31.2 bits (69), Expect = 3.2
 Identities = 63/255 (24%), Positives = 80/255 (31%), Gaps = 63/255 (24%)

Query: 81  PSIFGVKNK-GDGKSSGPTGLVRSRTHDGLAEVLVLESGRKEEPRGGGDSGGGGGGRPNP 139
           P   G K + GD    GP G+       G       + G++  P       G  GGR  P
Sbjct: 558 PGSSGAKGESGDPGPQGPRGVQGPPGPTG-------KPGKRGRP-------GADGGRGMP 603

Query: 140 GPPRAAGPGG-GSLASSSVAKSHSFFSLLKKNGRSENG----KGEPVDASKAGGKQKRGL 194
           G P A G  G   L      K H          R E G     G P D    G   + G 
Sbjct: 604 GEPGAKGDRGFDGLPGLPGDKGH----------RGERGPQGPPGPPGDDGMRGEDGEIGP 653

Query: 195 RGLFSGMRWHRKDKRAKAEAAEGRAPGGGLILPGSLTASLECVKEETPRAAREPEEPSQD 254
           RGL                   G A   GL+ P             TP A  +P     D
Sbjct: 654 RGL------------------PGEAGPRGLLGP-----------RGTPGAPGQPGMAGVD 684

Query: 255 APRDPAGE--PAGGEEVPAPADRAPARSCREAEG-LAHPGDTGARGEDA-AGHRRAEPGP 310
            P  P G   P G    P        +     +G +  PG+ G +G+   AG   A+  P
Sbjct: 685 GPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPP 744

Query: 311 GEVRTAEDASRTGAV 325
           G       +   GA+
Sbjct: 745 GHPGKEGQSGEKGAL 759



 Score = 30.8 bits (68), Expect = 4.2
 Identities = 35/117 (29%), Positives = 44/117 (37%), Gaps = 25/117 (21%)

Query: 251 PSQDAPRDPAGEPA-----GGEEVPA-PADRAPARSCREAEGL-AHPGDTGARGEDAAGH 303
           P  D  R   GEP      G + +P  P D+   R  R  +G    PGD G RGED    
Sbjct: 594 PGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGH-RGERGPQGPPGPPGDDGMRGEDGEIG 652

Query: 304 RRAEPGPGEVRTAEDASRTGAVPVKTVPLVDSEGGSGRAPAAPDPASVDPPSDPSAD 360
            R  PG        +A   G +  +         G+  AP  P  A VD P  P  +
Sbjct: 653 PRGLPG--------EAGPRGLLGPR---------GTPGAPGQPGMAGVDGPPGPKGN 692


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
           sapiens]
          Length = 1767

 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 91/340 (26%), Positives = 114/340 (33%), Gaps = 52/340 (15%)

Query: 118 GRKEEPRGGGDSGGGGG-GRPNP----GPPRAAGPGG----GSLASSSVAKSHSFFSLLK 168
           G + EP   G  G  G  G P P    GPP   GP G      L  +     H       
Sbjct: 643 GPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHP-----G 697

Query: 169 KNGRS--ENGKGEPVDASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEGRAPG--GGL 224
           K G+S  +   G P      G    RG++G   G+R     K +K E  E   PG  G +
Sbjct: 698 KEGQSGEKGALGPPGPQGPIGYPGPRGVKGA-DGVRGL---KGSKGEKGEDGFPGFKGDM 753

Query: 225 ILPGSLTASLECVKEETPRAAREPEEPSQDAPRDPAGEPA----GGEEVPAPADRAPARS 280
            L G        V +  PR    PE P   A   P G+P      GE+        P   
Sbjct: 754 GLKGDRGE----VGQIGPRGEDGPEGPKGRA--GPTGDPGPSGQAGEKGKLGVPGLPGYP 807

Query: 281 CREAE--GLAHPGDTGARGEDAAGHRRAEPGPGEVR--TAEDASRTGAVPVKTVPLVDSE 336
            R+        PG  GA GE  A     +PGP   R  T    SR    P        + 
Sbjct: 808 GRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTS 867

Query: 337 GGSG-------RAPAAPD-----PASVDPPSDPSADRICLMFSD--VTSLKSFDSLTGCG 382
           GG G       R P  P      P    PP  P  D +         T  +      G G
Sbjct: 868 GGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPG 927

Query: 383 DIIADQEE--EAGPSCDKHVPGPGKPALSKKNPGVVAYQG 420
            ++  Q    E GP  ++  PGP  P   +  PG    +G
Sbjct: 928 GVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEG 967



 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 80/324 (24%), Positives = 107/324 (33%), Gaps = 44/324 (13%)

Query: 123  PRGGGDSGGGGGGRPNPGPPRAAGPGGGSLASSSVAKSHSFFSLLKKNGRSENGK----G 178
            P G     G  G    PGPP   GP G + A        S  S+     + E G+    G
Sbjct: 1166 PPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPG 1225

Query: 179  EPVDASKAGGKQKRGLRGLFS--------GMRWHRKDKRAKAEAAEGRAPGGGLILPGSL 230
             P +A   G K +RG +G           G +    D   K        PG     PG  
Sbjct: 1226 PPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGD----PGPP 1281

Query: 231  TASLECVKEETPRAAREPEEPSQDAPRDPAGEPAGGEEVPAPADRAPARSCREAEGLAHP 290
                   ++       E  +P Q  P  P+GE       P P  +        AEG    
Sbjct: 1282 GEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAG----PPGPPGKRGPPGAAGAEG--RQ 1335

Query: 291  GDTGARGEDAAGHRRAEPGPGEVRTAEDASRTGAVPVKTVP-LVDSEGGSGRAPAAPDPA 349
            G+ GA+GE  A     + GP  V     A + G   ++ +P  V  +G  G A     P 
Sbjct: 1336 GEKGAKGEAGAEGPPGKTGP--VGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPG 1393

Query: 350  SVDPPSDPSADRICLMFSDVTSL--KSFDSLTGCGDIIADQEEEA-----------GPSC 396
             + PP  P       +  D  S   K    L G      +Q E+            G   
Sbjct: 1394 PMGPPGLPG------LKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKG 1447

Query: 397  DKHVPGPGKPALSKKNPGVVAYQG 420
            D  +PGP  P      PG+   QG
Sbjct: 1448 DGGIPGPAGPLGPPGPPGLPGPQG 1471



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 52/199 (26%), Positives = 68/199 (34%), Gaps = 29/199 (14%)

Query: 123  PRGGGDSGGGGGGRPNPGPPRAAGPGGGSLASSSVAKSHSFFSLLKKNGRSENGKGEPVD 182
            P+G     G  G R +PGPP   GP G      +  K              E  KG+P  
Sbjct: 932  PQGPTGETGPIGERGHPGPP---GPPGEQGLPGAAGK--------------EGAKGDPGP 974

Query: 183  ASKAGGKQKRGLRGLFSGMRWHRKDKRAKA-EAAEG-RAPGGGLILPGSLTASLECVK-- 238
               +G     GLRG F G R     + A   +  EG + P G +  PG   ++       
Sbjct: 975  QGISGKDGPAGLRG-FPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIG 1033

Query: 239  -------EETPRAAREPEEPSQDAPRDPAGEPAGGEEVPAPADRAPARSCREAEGLAHPG 291
                   +  P  A E   P +  P+ PAG       V  P    PA S  E       G
Sbjct: 1034 LPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIG 1093

Query: 292  DTGARGEDAAGHRRAEPGP 310
            + G +G          PGP
Sbjct: 1094 EPGQKGSKGDKGENGPPGP 1112



 Score = 33.5 bits (75), Expect = 0.65
 Identities = 72/276 (26%), Positives = 86/276 (31%), Gaps = 74/276 (26%)

Query: 96  GPTGLVRSRTHDGLAEVLVLESGRKEEPRGGGDSGGGGG-GRPNP-GPPRAAGPGG---- 149
           GP G    +   GLA  L    G    P   G SG  G  G P P GP    GP G    
Sbjct: 670 GPPGEKGPQGKPGLAG-LPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGA 728

Query: 150 ---GSLASSSVAKSHSFFSLLK-----KNGRSENGK-------------------GEPVD 182
                L  S   K    F   K     K  R E G+                   G+P  
Sbjct: 729 DGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGP 788

Query: 183 ASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEGR-APGGGLILPGSLTASLE-----C 236
           + +AG K K G+ GL                   GR  P G    PG   A+ E      
Sbjct: 789 SGQAGEKGKLGVPGL---------------PGYPGRQGPKGSTGFPGFPGANGEKGARGV 833

Query: 237 VKEETPRAAREPEEP-SQDAPRDPAGEP-----AGGEEVPAPADRAPARSCREAEGLAHP 290
             +  PR  R P  P      R P G+P     +GG+  P P      +  +   G   P
Sbjct: 834 AGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGP 893

Query: 291 -------------GDTGARGEDAAGHRRAEPGPGEV 313
                        G  G RGE     +   PGPG V
Sbjct: 894 KGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGV 929



 Score = 31.2 bits (69), Expect = 3.2
 Identities = 63/255 (24%), Positives = 80/255 (31%), Gaps = 63/255 (24%)

Query: 81  PSIFGVKNK-GDGKSSGPTGLVRSRTHDGLAEVLVLESGRKEEPRGGGDSGGGGGGRPNP 139
           P   G K + GD    GP G+       G       + G++  P       G  GGR  P
Sbjct: 507 PGSSGAKGESGDPGPQGPRGVQGPPGPTG-------KPGKRGRP-------GADGGRGMP 552

Query: 140 GPPRAAGPGG-GSLASSSVAKSHSFFSLLKKNGRSENG----KGEPVDASKAGGKQKRGL 194
           G P A G  G   L      K H          R E G     G P D    G   + G 
Sbjct: 553 GEPGAKGDRGFDGLPGLPGDKGH----------RGERGPQGPPGPPGDDGMRGEDGEIGP 602

Query: 195 RGLFSGMRWHRKDKRAKAEAAEGRAPGGGLILPGSLTASLECVKEETPRAAREPEEPSQD 254
           RGL                   G A   GL+ P             TP A  +P     D
Sbjct: 603 RGL------------------PGEAGPRGLLGP-----------RGTPGAPGQPGMAGVD 633

Query: 255 APRDPAGE--PAGGEEVPAPADRAPARSCREAEG-LAHPGDTGARGEDA-AGHRRAEPGP 310
            P  P G   P G    P        +     +G +  PG+ G +G+   AG   A+  P
Sbjct: 634 GPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPP 693

Query: 311 GEVRTAEDASRTGAV 325
           G       +   GA+
Sbjct: 694 GHPGKEGQSGEKGAL 708



 Score = 30.8 bits (68), Expect = 4.2
 Identities = 35/117 (29%), Positives = 44/117 (37%), Gaps = 25/117 (21%)

Query: 251 PSQDAPRDPAGEPA-----GGEEVPA-PADRAPARSCREAEGL-AHPGDTGARGEDAAGH 303
           P  D  R   GEP      G + +P  P D+   R  R  +G    PGD G RGED    
Sbjct: 543 PGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGH-RGERGPQGPPGPPGDDGMRGEDGEIG 601

Query: 304 RRAEPGPGEVRTAEDASRTGAVPVKTVPLVDSEGGSGRAPAAPDPASVDPPSDPSAD 360
            R  PG        +A   G +  +         G+  AP  P  A VD P  P  +
Sbjct: 602 PRGLPG--------EAGPRGLLGPR---------GTPGAPGQPGMAGVDGPPGPKGN 641


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 91/340 (26%), Positives = 114/340 (33%), Gaps = 52/340 (15%)

Query: 118  GRKEEPRGGGDSGGGGG-GRPNP----GPPRAAGPGG----GSLASSSVAKSHSFFSLLK 168
            G + EP   G  G  G  G P P    GPP   GP G      L  +     H       
Sbjct: 682  GPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHP-----G 736

Query: 169  KNGRS--ENGKGEPVDASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEGRAPG--GGL 224
            K G+S  +   G P      G    RG++G   G+R     K +K E  E   PG  G +
Sbjct: 737  KEGQSGEKGALGPPGPQGPIGYPGPRGVKGA-DGVRGL---KGSKGEKGEDGFPGFKGDM 792

Query: 225  ILPGSLTASLECVKEETPRAAREPEEPSQDAPRDPAGEPA----GGEEVPAPADRAPARS 280
             L G        V +  PR    PE P   A   P G+P      GE+        P   
Sbjct: 793  GLKGDRGE----VGQIGPRGEDGPEGPKGRA--GPTGDPGPSGQAGEKGKLGVPGLPGYP 846

Query: 281  CREAE--GLAHPGDTGARGEDAAGHRRAEPGPGEVR--TAEDASRTGAVPVKTVPLVDSE 336
             R+        PG  GA GE  A     +PGP   R  T    SR    P        + 
Sbjct: 847  GRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTS 906

Query: 337  GGSG-------RAPAAPD-----PASVDPPSDPSADRICLMFSD--VTSLKSFDSLTGCG 382
            GG G       R P  P      P    PP  P  D +         T  +      G G
Sbjct: 907  GGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPG 966

Query: 383  DIIADQEE--EAGPSCDKHVPGPGKPALSKKNPGVVAYQG 420
             ++  Q    E GP  ++  PGP  P   +  PG    +G
Sbjct: 967  GVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEG 1006



 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 80/324 (24%), Positives = 107/324 (33%), Gaps = 44/324 (13%)

Query: 123  PRGGGDSGGGGGGRPNPGPPRAAGPGGGSLASSSVAKSHSFFSLLKKNGRSENGK----G 178
            P G     G  G    PGPP   GP G + A        S  S+     + E G+    G
Sbjct: 1205 PPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPG 1264

Query: 179  EPVDASKAGGKQKRGLRGLFS--------GMRWHRKDKRAKAEAAEGRAPGGGLILPGSL 230
             P +A   G K +RG +G           G +    D   K        PG     PG  
Sbjct: 1265 PPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGD----PGPP 1320

Query: 231  TASLECVKEETPRAAREPEEPSQDAPRDPAGEPAGGEEVPAPADRAPARSCREAEGLAHP 290
                   ++       E  +P Q  P  P+GE       P P  +        AEG    
Sbjct: 1321 GEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAG----PPGPPGKRGPPGAAGAEG--RQ 1374

Query: 291  GDTGARGEDAAGHRRAEPGPGEVRTAEDASRTGAVPVKTVP-LVDSEGGSGRAPAAPDPA 349
            G+ GA+GE  A     + GP  V     A + G   ++ +P  V  +G  G A     P 
Sbjct: 1375 GEKGAKGEAGAEGPPGKTGP--VGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPG 1432

Query: 350  SVDPPSDPSADRICLMFSDVTSL--KSFDSLTGCGDIIADQEEEA-----------GPSC 396
             + PP  P       +  D  S   K    L G      +Q E+            G   
Sbjct: 1433 PMGPPGLPG------LKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKG 1486

Query: 397  DKHVPGPGKPALSKKNPGVVAYQG 420
            D  +PGP  P      PG+   QG
Sbjct: 1487 DGGIPGPAGPLGPPGPPGLPGPQG 1510



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 52/199 (26%), Positives = 68/199 (34%), Gaps = 29/199 (14%)

Query: 123  PRGGGDSGGGGGGRPNPGPPRAAGPGGGSLASSSVAKSHSFFSLLKKNGRSENGKGEPVD 182
            P+G     G  G R +PGPP   GP G      +  K              E  KG+P  
Sbjct: 971  PQGPTGETGPIGERGHPGPP---GPPGEQGLPGAAGK--------------EGAKGDPGP 1013

Query: 183  ASKAGGKQKRGLRGLFSGMRWHRKDKRAKA-EAAEG-RAPGGGLILPGSLTASLECVK-- 238
               +G     GLRG F G R     + A   +  EG + P G +  PG   ++       
Sbjct: 1014 QGISGKDGPAGLRG-FPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIG 1072

Query: 239  -------EETPRAAREPEEPSQDAPRDPAGEPAGGEEVPAPADRAPARSCREAEGLAHPG 291
                   +  P  A E   P +  P+ PAG       V  P    PA S  E       G
Sbjct: 1073 LPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIG 1132

Query: 292  DTGARGEDAAGHRRAEPGP 310
            + G +G          PGP
Sbjct: 1133 EPGQKGSKGDKGENGPPGP 1151



 Score = 33.5 bits (75), Expect = 0.65
 Identities = 72/276 (26%), Positives = 86/276 (31%), Gaps = 74/276 (26%)

Query: 96  GPTGLVRSRTHDGLAEVLVLESGRKEEPRGGGDSGGGGG-GRPNP-GPPRAAGPGG---- 149
           GP G    +   GLA  L    G    P   G SG  G  G P P GP    GP G    
Sbjct: 709 GPPGEKGPQGKPGLAG-LPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGA 767

Query: 150 ---GSLASSSVAKSHSFFSLLK-----KNGRSENGK-------------------GEPVD 182
                L  S   K    F   K     K  R E G+                   G+P  
Sbjct: 768 DGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGP 827

Query: 183 ASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEGR-APGGGLILPGSLTASLE-----C 236
           + +AG K K G+ GL                   GR  P G    PG   A+ E      
Sbjct: 828 SGQAGEKGKLGVPGL---------------PGYPGRQGPKGSTGFPGFPGANGEKGARGV 872

Query: 237 VKEETPRAAREPEEP-SQDAPRDPAGEP-----AGGEEVPAPADRAPARSCREAEGLAHP 290
             +  PR  R P  P      R P G+P     +GG+  P P      +  +   G   P
Sbjct: 873 AGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGP 932

Query: 291 -------------GDTGARGEDAAGHRRAEPGPGEV 313
                        G  G RGE     +   PGPG V
Sbjct: 933 KGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGV 968



 Score = 31.2 bits (69), Expect = 3.2
 Identities = 63/255 (24%), Positives = 80/255 (31%), Gaps = 63/255 (24%)

Query: 81  PSIFGVKNK-GDGKSSGPTGLVRSRTHDGLAEVLVLESGRKEEPRGGGDSGGGGGGRPNP 139
           P   G K + GD    GP G+       G       + G++  P       G  GGR  P
Sbjct: 546 PGSSGAKGESGDPGPQGPRGVQGPPGPTG-------KPGKRGRP-------GADGGRGMP 591

Query: 140 GPPRAAGPGG-GSLASSSVAKSHSFFSLLKKNGRSENG----KGEPVDASKAGGKQKRGL 194
           G P A G  G   L      K H          R E G     G P D    G   + G 
Sbjct: 592 GEPGAKGDRGFDGLPGLPGDKGH----------RGERGPQGPPGPPGDDGMRGEDGEIGP 641

Query: 195 RGLFSGMRWHRKDKRAKAEAAEGRAPGGGLILPGSLTASLECVKEETPRAAREPEEPSQD 254
           RGL                   G A   GL+ P             TP A  +P     D
Sbjct: 642 RGL------------------PGEAGPRGLLGP-----------RGTPGAPGQPGMAGVD 672

Query: 255 APRDPAGE--PAGGEEVPAPADRAPARSCREAEG-LAHPGDTGARGEDA-AGHRRAEPGP 310
            P  P G   P G    P        +     +G +  PG+ G +G+   AG   A+  P
Sbjct: 673 GPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPP 732

Query: 311 GEVRTAEDASRTGAV 325
           G       +   GA+
Sbjct: 733 GHPGKEGQSGEKGAL 747



 Score = 30.8 bits (68), Expect = 4.2
 Identities = 35/117 (29%), Positives = 44/117 (37%), Gaps = 25/117 (21%)

Query: 251 PSQDAPRDPAGEPA-----GGEEVPA-PADRAPARSCREAEGL-AHPGDTGARGEDAAGH 303
           P  D  R   GEP      G + +P  P D+   R  R  +G    PGD G RGED    
Sbjct: 582 PGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGH-RGERGPQGPPGPPGDDGMRGEDGEIG 640

Query: 304 RRAEPGPGEVRTAEDASRTGAVPVKTVPLVDSEGGSGRAPAAPDPASVDPPSDPSAD 360
            R  PG        +A   G +  +         G+  AP  P  A VD P  P  +
Sbjct: 641 PRGLPG--------EAGPRGLLGPR---------GTPGAPGQPGMAGVDGPPGPKGN 680


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 82/382 (21%), Positives = 130/382 (34%), Gaps = 38/382 (9%)

Query: 231 TASLECVKEETPRAAREPEEPSQDAPRDPAGEPAGGEEVPAPADRAPARSCREAEGLAHP 290
           T   E V EE  + A+E E   ++   +   E  G EE  +P     A   +EA+     
Sbjct: 464 TQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAE-GGEEETKSPPAEEAASPEKEAKSPVKE 522

Query: 291 GDTGARGEDAAGHRRAEPGPGEVRTAEDASRTGAVPVKTVPLVDSEGGSGRAPAAPDPAS 350
            +  +  E  +  +     P EV++ E A        K+ P    E  S     A  PA 
Sbjct: 523 -EAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPP----EAKSPEKEEAKSPAE 577

Query: 351 VDPPS---DPSADRICLMFSDVTSLKSFDSLTGCGDIIADQEEEAGPSCDKHVPGPGKPA 407
           V  P     P+ +            KS +         A    EA     +    P +  
Sbjct: 578 VKSPEKAKSPAKEEA----KSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVK 633

Query: 408 LSKKNPGVVAYQGGGEEMASPDEVDDTYLQEFWDMLSQTEEQGPEPQEGAAKVAAALETK 467
             +K     A     EE  SP++             S  +E+   P++  + V A  ++ 
Sbjct: 634 SPEK-----AKSPTKEEAKSPEKAK-----------SPEKEEAKSPEKAKSPVKAEAKSP 677

Query: 468 VVPETPKDTRCVEAAKDASSVKRRRLNRIPIEPHPKEEPKHPEKEQQEGVPNSDEGYWDS 527
              ++P         K  S VK    +    +   KEE K PEK +    P  +E     
Sbjct: 678 EKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKS---PVKEEAKTPE 734

Query: 528 TTPGPEEDSSSSGKKAGIPRDSYSGDALYDLYADPDGSPATLPGGKDNEETSSLSRLKPV 587
               P ++ + S +KA  P  + + D        P    A  P  K  E+  S  + +  
Sbjct: 735 KAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVK 794

Query: 588 SPGTITCPLRTPGSLLKDSKIP 609
           SP     PL+      +D+K P
Sbjct: 795 SPEKAKSPLK------EDAKAP 810



 Score = 38.5 bits (88), Expect = 0.020
 Identities = 41/179 (22%), Positives = 71/179 (39%), Gaps = 10/179 (5%)

Query: 459 KVAAALETKVVPETPKDTRCVEAAKDASSVKRRRLNRIPIEPHPKEEPKHPEKEQQEGVP 518
           KV +  + KVV ++ K+T  VE   + + V          E   KE  +   KE++ G  
Sbjct: 437 KVKSEEKIKVVEKSEKETVIVEEQTEETQVTEE-----VTEEEEKEAKEEEGKEEEGGEE 491

Query: 519 NSDEGYWDSTTPGPEEDSSSSGKKAGIP--RDSYSGDALYDLYADPDGSPATLPGGKDNE 576
              EG  + T   P E+++S  K+A  P   ++ S         +   SPA +   K  E
Sbjct: 492 EEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEV---KSPE 548

Query: 577 ETSSLSRLKPVSPGTITCPLRTPGSLLKDSKIPISIKHLTNLPSSHPVVHQQPSRSEMP 635
           +  S ++ +  SP     P +       + K P   K      +  P   + P +++ P
Sbjct: 549 KAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSP 607



 Score = 30.4 bits (67), Expect = 5.5
 Identities = 106/571 (18%), Positives = 176/571 (30%), Gaps = 80/571 (14%)

Query: 52  ETPAAEPPSGKINKAAFKLFKKRKSGGTMPSIFG----VKNKGDGKSSGPTGLVRSRTHD 107
           ET   E  + +  K A +   K + GG      G     K+    +++ P    +S   +
Sbjct: 463 ETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKE 522

Query: 108 GLAEVLVLESGRKEEPRGGGDSGGGGGGRPNPGPPRAAGPGGGSLASSSVAKSHSFFSLL 167
                   +S  KEE +   +            P +A  P      S   AKS       
Sbjct: 523 EAKSPAEAKSPEKEEAKSPAEV---------KSPEKAKSPAKEEAKSPPEAKSPE----- 568

Query: 168 KKNGRSENGKGEPVDASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEGRAPGGGLILP 227
           K+  +S      P  A     ++ +      S  +     K      AE ++P       
Sbjct: 569 KEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKS 628

Query: 228 GSLTASLECVKEETPRAAREPEE---PSQDAPRDP--AGEPAGGEEVPAPADRAPARS-C 281
            +   S E  K  T   A+ PE+   P ++  + P  A  P   E       ++P ++  
Sbjct: 629 PAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEA 688

Query: 282 REAEGLAHPGDTGARGEDAAGHRRAEPGPGEVRTAEDASRTGAVPVKTVPLVDSEGGSGR 341
           +  E    P    A+  + A     E      +           P K    V  E  S  
Sbjct: 689 KSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPE 748

Query: 342 APAAPDPASVDPPSDPSADRICLMFSDVTSLKSFDSLTGCGDIIADQEEEAGPSCDKHVP 401
              +P+ A       P A                             +EEA    DK   
Sbjct: 749 KAKSPEKAKTLDVKSPEAK-------------------------TPAKEEARSPADKFPE 783

Query: 402 GPGKPALSKKNPGVVAYQGGGEEMASPDEVDDTYLQEFWDMLSQTEEQGPEPQEGAAKVA 461
               P   +      A     E+  +P++     + +  ++ S  +E+  +PQE   K  
Sbjct: 784 KAKSPVKEEVKSPEKAKSPLKEDAKAPEKE----IPKKEEVKSPVKEE-EKPQEVKVKEP 838

Query: 462 AA-LETKVVPETPK-----DTRCVEAAKDASSVKRRRLNRIPIEPHPKEEPKHPEKEQQE 515
               E +  P TPK     D++  EA K  +   +    + P    PKE     +KE+ E
Sbjct: 839 PKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAE 898

Query: 516 G---VP------------NSDEGYWDSTTPGPEEDSSSSGKKAGIPRDSYSG-----DAL 555
               VP              D    + T    +E   +  K+   P +         D  
Sbjct: 899 DKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTK 958

Query: 556 YDLYADPDGSPATLPGGKDNEETSSLSRLKP 586
            +    P+  P T    K++++T S    KP
Sbjct: 959 EEKAKKPEEKPKTEAKAKEDDKTLSKEPSKP 989


>gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 819

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 67/248 (27%), Positives = 91/248 (36%), Gaps = 49/248 (19%)

Query: 5   RSRGGGGAVSERGGAGASVGVCRRKAEAGAGTGTLAADMDLHCDCAAETPAAEPPSGKIN 64
           +SRGGG     R G  A++   +R+  A AG                E PAA+   G+  
Sbjct: 265 KSRGGGDKKLRRQGQNAALAGAKRRGAATAG----------------EKPAAKGRGGRGP 308

Query: 65  KA----------AFKLFKKRKSGGTMPSIFGVKNKGDGKSSGPTGLVRSRTHD---GLAE 111
           K+            K  ++R    T  +  G K  G G+       V+SR      G   
Sbjct: 309 KSLGGQNPRWGRGGKKPRRRGQKATKAAAAGTKRGGGGQQKAAVVGVKSRKKQRRRGKKP 368

Query: 112 VLVLESGRKEEPRGGGDSGG------GGGGRPNP---GPPR------AAGPGGGSLASSS 156
                S    + RGGGD  G       G GR  P    P R      AA P GG    S 
Sbjct: 369 RRQKASAAGAKSRGGGDKKGLREAKRRGDGRKKPRWQNPRRRAQKAPAAKPRGG---GSK 425

Query: 157 VAKSHSFFSLLKKNGRSENGKGEPVDASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAE 216
             +     +   + G+S +G G+         +QK    G  S  R  +K  R KA AA 
Sbjct: 426 KPRRRGPKAAKSRGGKSRSGGGKKPRRRGQKARQKAAEAGAES--RGDKKQGRQKASAAG 483

Query: 217 GRAPGGGL 224
            ++ GGGL
Sbjct: 484 TKSRGGGL 491



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 76/322 (23%), Positives = 108/322 (33%), Gaps = 58/322 (18%)

Query: 73  KRKSGGTMPSIFGVKNKGDGKSSGPTGLVRSRTHDGLAEVLVLESGRKEEPRG------- 125
           K + GG    +   K +GDG+        R R     A        +K   RG       
Sbjct: 379 KSRGGGDKKGLREAKRRGDGRKKPRWQNPRRRAQKAPAAKPRGGGSKKPRRRGPKAAKSR 438

Query: 126 GGDSGGGGGGRPN----PGPPRAAGPGG----------------GSLASSSVAKSHSFFS 165
           GG S  GGG +P         +AA  G                 G+ +     KSHS  +
Sbjct: 439 GGKSRSGGGKKPRRRGQKARQKAAEAGAESRGDKKQGRQKASAAGTKSRGGGLKSHSGKN 498

Query: 166 LLKKNGRSENG--KGEPVDASKAGGKQKR----GLRGLFSGMRWHRKDKRAKAEAAEGRA 219
           L ++  ++E    K     A   G KQ R     + G  S +   +  +R KA AA   +
Sbjct: 499 LWRRGQKAEAAGEKATAAGAKSRGRKQPRRQKPAVAGAKSRVGGSKSRQRQKAVAAGATS 558

Query: 220 PGGGLILPGSLTASLECVKEETPRAAREPEEPSQDAPRDPAGEPAGGEEVPA-PADRAPA 278
            GGG    G+        K+       +P +  Q A    A    GG++ P      A  
Sbjct: 559 HGGG----GN--------KQSRGGGGNKPRQWGQTAA--AAKTRGGGDKQPGWQKAAAGV 604

Query: 279 RSCREAEGLAHPGDTGARGEDAAGHRRA-EPGPGEVRTAEDASRTGAVPVKTVPLVDSEG 337
              R  +G        A G  A   ++    G  +   AE A  TGA          S G
Sbjct: 605 TKSRSGDGGKKAWRQKAAGTGAKSRKKPWRRGQKDAAAAEKAWATGAT---------SRG 655

Query: 338 GSGRAPAAPDPASVDPPSDPSA 359
             G+ P    PA+    S  +A
Sbjct: 656 SGGKQPRWQKPAAAGSESSAAA 677



 Score = 35.4 bits (80), Expect = 0.17
 Identities = 29/103 (28%), Positives = 39/103 (37%), Gaps = 1/103 (0%)

Query: 119 RKEEPRGGGDSGGGGGGRPNPGPPRAAGPGGG-SLASSSVAKSHSFFSLLKKNGRSENGK 177
           R ++PR G   GGGG      G  ++ G GG  S +    A S S      K  R    K
Sbjct: 714 RGKKPRLGKSRGGGGAKSRGSGGAKSRGSGGAKSRSGKKAAASKSHGGGGAKRRRGGGAK 773

Query: 178 GEPVDASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEGRAP 220
               + +   G QK    G     R   +  R +  AA G+ P
Sbjct: 774 SRSGEKAVTAGGQKAAAAGGKKPPRVKSRGGRGQKAAAGGKKP 816



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 27/86 (31%), Positives = 32/86 (37%), Gaps = 7/86 (8%)

Query: 118 GRKEEPRGGGDSGGGGGGRPNPGPPRAA----GPGGGSLASSSVAKSHSFFSLLKKNGR- 172
           G K    GG  S G GG +   G   AA    G GG        AKS S    +   G+ 
Sbjct: 728 GAKSRGSGGAKSRGSGGAKSRSGKKAAASKSHGGGGAKRRRGGGAKSRSGEKAVTAGGQK 787

Query: 173 --SENGKGEPVDASKAGGKQKRGLRG 196
             +  GK  P   S+ G  QK    G
Sbjct: 788 AAAAGGKKPPRVKSRGGRGQKAAAGG 813



 Score = 31.2 bits (69), Expect = 3.2
 Identities = 62/274 (22%), Positives = 87/274 (31%), Gaps = 33/274 (12%)

Query: 6   SRGGGGAVSERGGAGASVGVCRRKAEAGAGTGTLAADMDLHCDCAAETPAAEPPSGKINK 65
           S GGGG    RGG G      R+  +  A               AA+T           K
Sbjct: 558 SHGGGGNKQSRGGGGNKP---RQWGQTAA---------------AAKTRGGGDKQPGWQK 599

Query: 66  AAFKLFKKRKSGGTMPSIFGVKNKGDGKSSGPTGLVRSRTHDGLAEVLVLESGRKEEPRG 125
           AA  + K R   G   + +  K  G G  S      R +     AE         +    
Sbjct: 600 AAAGVTKSRSGDGGKKA-WRQKAAGTGAKSRKKPWRRGQKDAAAAE---------KAWAT 649

Query: 126 GGDSGGGGGGRPNPGPPRAAGPGGGSLASSSVAKSHSFFSLLKKNGRSENGKGEPVDASK 185
           G  S G GG +P    P AAG    S A+++V +        ++      G G    A  
Sbjct: 650 GATSRGSGGKQPRWQKPAAAG--SESSAAAAVGQEAEARKKPRRRRAKSRGDGGQNAAVG 707

Query: 186 AGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEGRAPGGGLILPGSLTASLECVKEETPRAA 245
               Q+RG +      R     K   +  A+ R  GG     G   A+    K      A
Sbjct: 708 INPWQRRGKKPRLGKSRGGGGAKSRGSGGAKSRGSGGAKSRSGKKAAA---SKSHGGGGA 764

Query: 246 REPEEPSQDAPRDPAGEPAGGEEVPAPADRAPAR 279
           +        +        AGG++  A   + P R
Sbjct: 765 KRRRGGGAKSRSGEKAVTAGGQKAAAAGGKKPPR 798


>gi|182507165 thymus expressed gene 3-like [Homo sapiens]
          Length = 629

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 47/149 (31%), Positives = 61/149 (40%), Gaps = 13/149 (8%)

Query: 214 AAEGRAPGGGLILPGSLTASLECVKEETPRAAREPEEPSQDAPRDPAGEPAGGEEVPAPA 273
           +AE RA  G  + P  L A    V   +PR    P   S DA    AG P  G  + A  
Sbjct: 205 SAERRARAGPFLTPSPLHA----VAMRSPRPCGRPPTDSPDA--GGAGRPLDGY-ISALL 257

Query: 274 DRAPARSCREAEGLAHPGDTGARGEDAAGHRR--AEPGPGEVRTAEDAS--RTGAVPVKT 329
            R   R   +        D G R +++   R   A P PG  R A + S  R G  P   
Sbjct: 258 RRRRRRGAGQPRTSPGGADGGPRRQNSVRQRPPDASPSPGSARPAREPSLERVGGHPTSP 317

Query: 330 VPLVDSEGGSGRAPAAPDPASVDPPSDPS 358
             L  +   S  + AAP+PA+  PP+ PS
Sbjct: 318 AALSRAWASSWESEAAPEPAA--PPAAPS 344


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 59/217 (27%), Positives = 78/217 (35%), Gaps = 36/217 (16%)

Query: 387 DQEEEAGPSCDKHVPGPGKPALSKKNPGVVAYQGGGEEMASPDEVDDTYLQEFWDMLSQT 446
           D  E   P CD  VP    P     NP     +G GE         +TY  E+       
Sbjct: 235 DYCEHYSPDCDTAVPDT--PQSQDPNPDEYYTEGDGE--------GETYYYEY-PYYEDP 283

Query: 447 EEQGPEPQEGAAKVAAALETKVVPE--TPKDTRCV------EAAKDASSVKRRRLNRIPI 498
           E+ G EP      V AA ET  VPE  TP  T         E A     V     + +P 
Sbjct: 284 EDLGKEPTPSKKPVEAAKETTEVPEELTPTPTEAAPMPETSEGAGKEEDVGIGDYDYVPS 343

Query: 499 E----PHPKEEPKHPEKEQQEGVP-NSDEGYWDSTTPGPEEDSSSSGKKAGIPRDSYSG- 552
           E    P P ++  + E E+    P +   G    T+     +SS+     G   D   G 
Sbjct: 344 EDYYTPSPYDDLTYGEGEENPDQPTDPGAGAEIPTSTADTSNSSNPAPPPGEGADDLEGE 403

Query: 553 ----------DALYDLYADPDGSPATL-PGGKDNEET 578
                     +  YD Y DP  SP+ + PG   N++T
Sbjct: 404 FTEETIRNLDENYYDPYYDPTSSPSEIGPGMPANQDT 440



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 72/281 (25%), Positives = 88/281 (31%), Gaps = 67/281 (23%)

Query: 88   NKGDGKSSGPTGLVRSRTHDGLAEVLVLESGRKEEPRGGGDSG-----GGGGGRPNPGPP 142
            +KG+    GPTG        G        SG   EP   G  G     G  G R  PGPP
Sbjct: 1172 DKGEQGPPGPTGPQGPIGQPG-------PSGADGEPGPRGQQGLFGQKGDEGPRGFPGPP 1224

Query: 143  RAAGPGGGSLASSSVAKSHSFFSLLKKNGRSENGKGEPVDASKAGGKQKRGLRGLFSGMR 202
               GP G                 L+        KGE  D  + G     G RG      
Sbjct: 1225 ---GPVG-----------------LQGLPGPPGEKGETGDVGQMGPPGPPGPRG------ 1258

Query: 203  WHRKDKRAKAEAAEG-RAPGGGLILPGSLTASLECVKEETPRAAREPEEPSQDAPRDPAG 261
                   + A  A+G + P GG+  PG++    E      P  A EP  P +  P  P G
Sbjct: 1259 ------PSGAPGADGPQGPPGGIGNPGAVGEKGE------PGEAGEPGLPGEGGPPGPKG 1306

Query: 262  EPAG-GEEVPAPADRAPARSCREAEGLAHPGDTGARGEDAAGHRRAEPGPGEVRTAEDAS 320
            E    GE  P+ A   P            PGD G +G         +PGP          
Sbjct: 1307 ERGEKGESGPSGAAGPPGPK-------GPPGDDGPKGSPGPVGFPGDPGP--------PG 1351

Query: 321  RTGAVPVKTVPLVDSEGGSGRAPAAPDPASVDPPSDPSADR 361
              G       P    + G      +P P     PS P   R
Sbjct: 1352 EPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKR 1392



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 61/232 (26%), Positives = 78/232 (33%), Gaps = 37/232 (15%)

Query: 123  PRGGGDSGGGGGGRPNPGPPRAAGPGGGSLASSSVAKSHSFFSLLKKNGRSENGKGEPVD 182
            P   G++G  G   P PGPP   GP G   A                N  +   KGEP +
Sbjct: 1236 PGEKGETGDVGQMGP-PGPPGPRGPSGAPGADGPQGPPGGI-----GNPGAVGEKGEPGE 1289

Query: 183  ASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEGRAPGGGLILPGSLTASLECVKEETP 242
            A + G   + G  G           K  + E  E   P G    PG      +   + +P
Sbjct: 1290 AGEPGLPGEGGPPG----------PKGERGEKGES-GPSGAAGPPGPKGPPGDDGPKGSP 1338

Query: 243  RAAREPEEPSQDAPRDPAGEPAGGEEVPAPADRAPARSCREAEGLAHPGDTGARGEDAAG 302
                 P +P       P GEP    +   P D+       E      PG TG  G     
Sbjct: 1339 GPVGFPGDPG------PPGEPGPAGQDGPPGDKGDDG---EPGQTGSPGPTGEPGPSGPP 1389

Query: 303  HRRAEPGPG--EVRTAEDASRTGA----VPVKTVPLVDSEGGSGRAPAAPDP 348
             +R  PGP   E R  E  ++  A     P KT P+     G   AP  P P
Sbjct: 1390 GKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPI-----GPQGAPGKPGP 1436



 Score = 38.5 bits (88), Expect = 0.020
 Identities = 107/432 (24%), Positives = 132/432 (30%), Gaps = 59/432 (13%)

Query: 123  PRGGGDSGGGGGGRPNPGPPRAAGPGGGSLASSSVAKSHSFFSLLKKNGRSENGKGEPVD 182
            P+G     G  G R +PGPP   G  G                 L      E  KG+P  
Sbjct: 1001 PQGPTGETGPMGERGHPGPPGPPGEQG-----------------LPGLAGKEGTKGDPGP 1043

Query: 183  ASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEGRAPGGGLILPGSLTASLECVKEETP 242
            A   G     GLRG F G R       A         PG     PG   +  E       
Sbjct: 1044 AGLPGKDGPPGLRG-FPGDRGLPGPVGALGLKGNEGPPGP----PGPAGSPGERGPAGAA 1098

Query: 243  RAAREPEEPSQDAPRDPAGEP-AGGEEVP-APADRAPARSCREAEGLAHP-GDTGARGED 299
                 P  P    P  PAGE  A GE+ P  PA R      +   GL  P G  G  GED
Sbjct: 1099 GPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGR---DGLQGPVGLPGPAGPVGPPGED 1155

Query: 300  AAGHRRAEPGPGEVRTAEDASRTGAVPVKTVPL--VDSEGGSGRAPAAPDPASVDPPSDP 357
              G +     PG+  +  D    G  P  T P   +   G SG A   P P         
Sbjct: 1156 --GDKGEIGEPGQKGSKGDKGEQGP-PGPTGPQGPIGQPGPSG-ADGEPGPRGQQGLFGQ 1211

Query: 358  SADRICLMFSDVTSLKSFDSLTGCGDIIADQEEEAGPSCDKHVPGPGKPALSKKNPGVVA 417
              D     F           L G       ++ E G       PGP  P      PG   
Sbjct: 1212 KGDEGPRGFPGPPGPVGLQGLPG----PPGEKGETGDVGQMGPPGPPGPRGPSGAPGADG 1267

Query: 418  YQG--GG-------EEMASPDEVDDTYLQEFWDMLSQTEEQGPEPQEGAAKVAAALETKV 468
             QG  GG        E   P E  +  L           E+G + + G +  A       
Sbjct: 1268 PQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAG------ 1321

Query: 469  VPETPKDTRCVEAAKDASSVKRRRLNRIPIEPHPKEEPKHPEKEQQEGVPNSDEGYWDST 528
             P  PK     +  K +           P +P P  EP    ++   G    D     + 
Sbjct: 1322 -PPGPKGPPGDDGPKGSPGPV-----GFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTG 1375

Query: 529  TPGPEEDSSSSG 540
            +PGP  +   SG
Sbjct: 1376 SPGPTGEPGPSG 1387



 Score = 36.6 bits (83), Expect = 0.077
 Identities = 86/346 (24%), Positives = 110/346 (31%), Gaps = 64/346 (18%)

Query: 118  GRKEEPRGGGDSGGGGG-GRPNP----GPPRAAGP-GGGSLASSSVAKSHSFFSLLKKNG 171
            G + EP   G  G  G  G P P    GPP   GP G   L     A         +   
Sbjct: 712  GPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPP 771

Query: 172  RSENGKGEPVDASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEGRAPG--GGLILPGS 229
              + G+G P      G    RG++G   G+R     K  K E  E   PG  G + + G 
Sbjct: 772  GEKGGQGPPGPQGPIGYPGPRGVKGA-DGIRGL---KGTKGEKGEDGFPGFKGDMGIKGD 827

Query: 230  LTASLECVKEETPRAAREPEEPS-------QDAPRDPAGEPA--GGEEVPA-PADRAPAR 279
                   +    PR    PE P           P  P GE    G   +P  P  + P  
Sbjct: 828  RGE----IGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKG 883

Query: 280  SCR---------EAEGLAHPGDTGARGEDAAGHRRAEPGPGEVRTAEDASRTGAVPVKTV 330
            S           E  G   PG  G RG+      R E GP  +        TG    K  
Sbjct: 884  SIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGI--------TGKPGPK-- 933

Query: 331  PLVDSEGGSG-------RAPAAPD-----PASVDPPSDPSADRICLMFSD--VTSLKSFD 376
                + GG G       R P  P      P    PP  P  D +         T  +   
Sbjct: 934  ---GNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKT 990

Query: 377  SLTGCGDIIADQ--EEEAGPSCDKHVPGPGKPALSKKNPGVVAYQG 420
               G   ++  Q    E GP  ++  PGP  P   +  PG+   +G
Sbjct: 991  GPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEG 1036


>gi|59806361 hypothetical protein LOC387104 [Homo sapiens]
          Length = 947

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 51/173 (29%), Positives = 64/173 (36%), Gaps = 24/173 (13%)

Query: 125 GGGDSGGGG---GGRPNPGPPRA----------AGPGGGSLASSSVAKSHSFFSLLKKNG 171
           GGG  GG G   GG P P PPR            G  GG  AS S + S    S  K  G
Sbjct: 173 GGGAGGGSGEREGGAPQPPPPRGWRGKGVRAQQRGGSGGEGASPSPSSS----SAGKTPG 228

Query: 172 RSENGKGEPVDASKAGGKQKRGLRGLFSG--MRWHRKDKRAKAEAAEGR---APGGGLIL 226
                 G  V    +GG       G      +++H K +RA A AA  +     GGG   
Sbjct: 229 TGSRNSGSGVAGGGSGGGGSYWKEGCLQSELIQFHLKKERAAAAAAAAQMHAKNGGGSSS 288

Query: 227 PGSLTASLECVKEETPRAAREPEEPSQDAPRDPAGEPA--GGEEVPAPADRAP 277
             S  +    V E    A+  P   + + P+  A   A  GG +  AP    P
Sbjct: 289 RSSPVSGPPAVCETLAVASASPMAAAAEGPQQSAEGSASGGGMQAAAPPSSQP 341



 Score = 32.3 bits (72), Expect = 1.5
 Identities = 58/256 (22%), Positives = 81/256 (31%), Gaps = 76/256 (29%)

Query: 9   GGGAVSERGGAGASVGVCRRKAEAGAGTGTLAADMDLHCDCAAETPAAEPPSGKINKAAF 68
           GGG   E GGAG   G    + E GA                   P   PP G   K   
Sbjct: 166 GGGGGGEGGGAGGGSG----EREGGA-------------------PQPPPPRGWRGKGV- 201

Query: 69  KLFKKRKSGGTMPSIFGVKNKGDGKSSGPTGLVRSRTHDGLAEVLVLESGRKEEPRGGGD 128
              + ++ GG         + G+G S  P+     +T            G      G G 
Sbjct: 202 ---RAQQRGG---------SGGEGASPSPSSSSAGKT-----------PGTGSRNSGSGV 238

Query: 129 SGGGGGGRPNPGPPRAAGPGGGSLASSSVAKSHSFFSLLKKNGRSENGKGEPVDASKAGG 188
           +GGG G             GGGS       +S      LKK   +       + A   GG
Sbjct: 239 AGGGSG-------------GGGSYWKEGCLQSELIQFHLKKERAAAAAAAAQMHAKNGGG 285

Query: 189 KQKR-----GLRGLFSGMRWHRKDKRAKA-----EAAEGRAPGGGLILPGSLTASLECVK 238
              R     G   +   +        A A     ++AEG A GGG      + A+     
Sbjct: 286 SSSRSSPVSGPPAVCETLAVASASPMAAAAEGPQQSAEGSASGGG------MQAAAPPSS 339

Query: 239 EETPRAAREPEEPSQD 254
           +  P+  +E EE  ++
Sbjct: 340 QPHPQQLQEQEEMQEE 355


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 139/628 (22%), Positives = 196/628 (31%), Gaps = 116/628 (18%)

Query: 50   AAETPAAEPPSGKINKAAFKLFK-----------KRKSGGTMPSIFGVKNKGDGKSSGPT 98
            A+  PAA PPS K + AA  L K             K G   PS+ G           P 
Sbjct: 1032 ASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPK 1091

Query: 99   GLVRSRTHDGLAEVLVLESGRKEEPRGGGDSGGGGGGRPNPGPPRAAGPGGGSLASSSVA 158
            G   + +  G     +  +     P+GG  +    G    P     +  GG +      A
Sbjct: 1092 GGPATPSPKGAP---MPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGA 1148

Query: 159  KSHSFFSLLKKNG--RSENGKGEPVDASKAGGKQKRGLRGLFSGMRWHRKDKRAKAE-AA 215
             +    +     G   +   KG P   +      K GL             K A    AA
Sbjct: 1149 PTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLAT--------PSPKGAPTTPAA 1200

Query: 216  EGRAPGGGLILPGSLTA-SLECVKEETPRAAREPEEPSQDAPRDPAG---EPAGGEEVPA 271
               +P GGL  P    A +       +P+       P + AP  PA     P GG   P 
Sbjct: 1201 TPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSP-KGAPTTPAATPPSPKGGPATPP 1259

Query: 272  P--ADRAPARSCREAEG-LAHPGDTGARGEDAAGHRRAEPGPGEVRTAEDASRTGAVPVK 328
            P  A   PA +    +G LA P   GA           + GP               P  
Sbjct: 1260 PKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPA----TSPPKGAPTPPAA 1315

Query: 329  TVPLVDSEGGSGRAPAAPDPASVDPPSDPSADRICLMFSDVTSLKSFDSLTGCGDIIADQ 388
            T P      G+     AP P +V PPS      +       T+  S              
Sbjct: 1316 TPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTL-----PATTPSS-------------- 1356

Query: 389  EEEAGPSCDKHVPGPGKPALSKKNPGVVAYQGGGEEMASPDEVDDTYLQEFWDMLSQTEE 448
              + GP+      GP  PA +  +        GG  M  P       +            
Sbjct: 1357 --KGGPTTPSSKEGPTPPAATPSHK-------GGPAMTPPSPKRGPAI------------ 1395

Query: 449  QGPEPQ-EGAAKVAAALETKVVPETP--KDTRCVEAAKDAS--SVKRRRLNRIPIEPHPK 503
              P P+ +  +     L  K  P TP  ++     +  D +  +V    L + P    PK
Sbjct: 1396 --PSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPK 1453

Query: 504  EEPKHPEKEQQEGVPNSDEGYWDSTTPGPEED-------SSSSGKKAGIPRDSYSGDALY 556
              P  P  +    +P         T P P+E        +SSS KKA           L 
Sbjct: 1454 GGPATPSSKGDPTLP-------AVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTL- 1505

Query: 557  DLYADPDGSPATLPGGKDNEETSSLSRLKPVSPGTITCPLRTPGSLL-KDSKIPISIKHL 615
                     PA +P        +  SR  P++P       +TP +L  K++ IP ++   
Sbjct: 1506 ---------PAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAM--T 1554

Query: 616  TNLPSSHPVVHQQPSRSEMPRTKIPVSK 643
               P   P +   P+  E P T  P SK
Sbjct: 1555 VPSPKKTPAI---PTPKEAPAT--PSSK 1577



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 45/162 (27%), Positives = 55/162 (33%), Gaps = 24/162 (14%)

Query: 214  AAEGRAPGGGLILPGSLTASLECVKEETPRAAREPEEPSQDAPRDPAG----------EP 263
            AA   +P GG   P    A        TP AA  P      A   P G           P
Sbjct: 944  AATPPSPKGGPATPSPKWAP-------TPPAATPPSPKGGPATPSPKGAPTPPAATPPSP 996

Query: 264  AGGEEVPAP--ADRAPARSCREAEG--LAHPGDTGARGEDAAGHRRAEPGPGEVRTAEDA 319
             GG   P+P  A   PA +    +G   A P   GA    AA     +  P      + A
Sbjct: 997  KGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGA 1056

Query: 320  SRTGAVPV---KTVPLVDSEGGSGRAPAAPDPASVDPPSDPS 358
              T A  +   K  P   S  G+   PAA  P+    P+ PS
Sbjct: 1057 PTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPS 1098


>gi|148833506 obscurin, cytoskeletal calmodulin and titin-interacting
            RhoGEF isoform b [Homo sapiens]
          Length = 7968

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 94/365 (25%), Positives = 122/365 (33%), Gaps = 84/365 (23%)

Query: 139  PGPPRAAGPGGGSLASSSVAKSHSFFSLLKKNGRSENGK-GEPVDASKAGGKQKRGL--- 194
            P PP A+  G G  A+      HS    L  +   E+ + G     S+    ++R L   
Sbjct: 6846 PAPP-ASPEGAGPPAAQGCVPRHSVIRSLFYHQAGESPEHGALAPGSRRHPARRRHLLKG 6904

Query: 195  ---RGLFSGMRWHRKDKR---------------AKAEAAEG--RAPGGGLILPGSLTASL 234
                G   G+R    + R               AKA + E   R P  G  L    + SL
Sbjct: 6905 GYIAGALPGLREPLMEHRVLEEEAAREEQATLLAKAPSFETALRLPASGTHLAPGHSHSL 6964

Query: 235  ECVKEETPR--------AAREPEEPSQDAPRDPAGEPAGGEEVPA---------PADRAP 277
            E     TPR        A R P  PS  AP    G P G +++P+         P   +P
Sbjct: 6965 EHDSPSTPRPSSEACGEAQRLPSAPSGGAPIRDMGHPQGSKQLPSTGGHPGTAQPERPSP 7024

Query: 278  ARSCREAEGLAHPGDTGARGEDAAGHRRAEPGPGEVRTAEDASRTGAVP---VKTVPLVD 334
                 +     HP    A  E  + H    P P            G+ P    K  PLV 
Sbjct: 7025 DSPWGQPAPFCHPKQGSAPQEGCSPHPAVAPCP-----------PGSFPPGSCKEAPLVP 7073

Query: 335  SEGGSGRAPAAPDPASVDPPSDPSADRICLMFSDVTSLKSFDSLTGCGDIIADQEEEAGP 394
            S    G+  A P PA   PP                     DS  G GDI      + GP
Sbjct: 7074 SSPFLGQPQAPPAPAKASPP--------------------LDSKMGPGDISLPGRPKPGP 7113

Query: 395  SCDKHVPGPGKPALSKK--NPGVVAYQGGGEEMASPDEVDDTYLQEFWDMLSQTEEQGPE 452
                  PG    A S +  +  V + Q G E   S D   + + QE  D LS +      
Sbjct: 7114 CSS---PGSASQASSSQVSSLRVGSSQVGTEPGPSLDA--EGWTQEAED-LSDSTPTLQR 7167

Query: 453  PQEGA 457
            PQE A
Sbjct: 7168 PQEQA 7172



 Score = 33.5 bits (75), Expect = 0.65
 Identities = 28/106 (26%), Positives = 43/106 (40%), Gaps = 9/106 (8%)

Query: 25  VCRRKAEAGAGTGTLAADMDLHCDCAAETP--AAEPPSGKINKAAFKLFKKRKSGGTMPS 82
           VCR +   G     +   +D    CA + P     P S ++ + +   F+ R  G   P+
Sbjct: 81  VCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPA 140

Query: 83  IFGVKNKGDGKSSGPTGLVRSRTHD-GLAEVLVLESGRKEEPRGGG 127
           +   K   DG+  G     R R  + G A  L + + R   PR GG
Sbjct: 141 VSWSK---DGRRLGEPDGPRVRVEELGEASALRIRAAR---PRDGG 180


>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
          Length = 1626

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 93/353 (26%), Positives = 116/353 (32%), Gaps = 92/353 (26%)

Query: 123  PRGGGDSGG-----GGGGRPNP----GPPRAAGPGG--GSLASSSVAKSHSFFSLLKKNG 171
            P G G S G     G  G+P P    GPP   GP G  G   +           L  K G
Sbjct: 724  PPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPG 783

Query: 172  -RSENGKGEPVDASKAGGKQKRGLRGL--FSGMRWHRKDKRAKAEAA----------EGR 218
             R E G  E   A + G K + GL G   F G+R  + D+  K E            +G 
Sbjct: 784  LRGEIG--EQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGE 841

Query: 219  A-PGGGLILPGS---LTASLECVKEETPRAAR-------EPE---EPSQDAPRDPAGEP- 263
            A P G   LPG+    T       E+ P+  +       EP     P +  P+ P G P 
Sbjct: 842  AGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPG 901

Query: 264  AGGEE-----------------VPAPADRAPARSCREAEGLAHPGDTGARGEDAAGHRRA 306
            A G+E                 V AP    P  S         PG  G RGE  A     
Sbjct: 902  AKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEG 961

Query: 307  EPGPGEVRTAEDASRTGAVPVKTVPLVDSEGGSGRAPAAPDPASVDPPSDPSADRICLMF 366
             PGP   R    A      P K     D E G   +P  P P                  
Sbjct: 962  SPGPVGPRGDPGAPGLPGPPGKG---KDGEPGLRGSPGLPGP------------------ 1000

Query: 367  SDVTSLKSFDSLTGCGDIIADQEEEAGPSC---DKHVPG-PGKPALSKKNPGV 415
                      +   CG +   +    G  C   D+  PG PG P  S+ +PG+
Sbjct: 1001 --------LGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPG-SRGDPGI 1044



 Score = 32.0 bits (71), Expect = 1.9
 Identities = 54/217 (24%), Positives = 66/217 (30%), Gaps = 26/217 (11%)

Query: 222 GGLILPGSLTASLECVKEETPRAAREPEEPSQDAPRDPAGEPAGGEEVPAPADRAPARSC 281
           G L LPG             P    EP  P +   R P G P     +P P  R  A   
Sbjct: 533 GSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPG----LPGPPGRVGAPGL 588

Query: 282 REAEG-LAHPGDTGARGEDAAGHRRAEPG----PGEVRTAEDASRTGAVPVKTVP----- 331
           +   G     G+ G RG D    +  + G    PG    A      G V     P     
Sbjct: 589 QGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGS 648

Query: 332 LVDSEGGSGRAPA--------APDPASVDPPSDPSADRICLMFSDVTSLKSFDSLTGCGD 383
           +V  EG  G   A        AP P     P  P           +   K      G   
Sbjct: 649 VVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPG 708

Query: 384 IIADQEEEAGPSCDKHVPGPGKPALSKKNPGVVAYQG 420
           ++  Q    GP     VPGP  P  S   PG + + G
Sbjct: 709 LLGLQ----GPPGPPGVPGPPGPGGSPGLPGEIGFPG 741



 Score = 29.6 bits (65), Expect = 9.4
 Identities = 66/280 (23%), Positives = 89/280 (31%), Gaps = 41/280 (14%)

Query: 89   KGDGKSSGPTGLVRSRTHDGLAEVLVLESGRKEEPRGGGDSGGGGGGRPNPGPPRAAGPG 148
            KGD  + G  G   SR   G+             P G     G  G R  PG P   GP 
Sbjct: 1024 KGDRGAPGIPGSPGSRGDPGIGVA------GPPGPSGPPGDKGSPGSRGLPGFPGPQGPA 1077

Query: 149  GGSLASSSVAK-------------SHSFFSLLKKNGRSENGKGEPVDASKAGGKQKRGLR 195
            G   A  +  +             S    +LL K+  ++   G P      G K  +G+ 
Sbjct: 1078 GRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVP 1137

Query: 196  GLFSGMRWHRKDKRAKAEAAEGRAPGGGLILPGSLTASLECVKEETPRAAREPEEPSQDA 255
            G         K  R   E  +G A   GL  P  + A  +  + E        ++  Q  
Sbjct: 1138 G---------KPGREGTEGKKGEAGPPGLPGPPGI-AGPQGSQGERGADGEVGQKGDQGH 1187

Query: 256  P-----RDPAGEPA--GGEEVPAPADRAPARSCREAEGLAHP----GDTGARGEDAAGHR 304
            P       P G P   G + +   A     +     EG   P    G  G  GE+    R
Sbjct: 1188 PGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGR 1247

Query: 305  RAEPG-PGEVRTAEDASRTGAVPVKTVPLVDSEGGSGRAP 343
              +PG PGE   A +    G    +  P      G   AP
Sbjct: 1248 DGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAP 1287


>gi|117938759 GNAS complex locus XLas [Homo sapiens]
          Length = 1037

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 42/130 (32%), Positives = 58/130 (44%), Gaps = 15/130 (11%)

Query: 239 EETPRAAREPEEPSQDAPRDPAGEPAGGEEVPAPADRAPARSCREAEGLAHPG------- 291
           ++  RA R P E  + A  + A + A G +VP+P   +PA     A+  A          
Sbjct: 344 DKRERAERPPVE-EEAAEMEGAADAAEGGKVPSPGYGSPAAGAASADTAARAAPAAPADP 402

Query: 292 DTGARGEDA-AGHRRAEPGPGEVRTAEDASRTGAVPVKTVPLVDSEGGSGRAPAAPDP-A 349
           D+GA  ED  +G   A+P  G      D   +GA P    P     G +  APA PD  A
Sbjct: 403 DSGATPEDPDSGTAPADPDSGAFAADPD---SGAAP--AAPADPDSGAAPDAPADPDSGA 457

Query: 350 SVDPPSDPSA 359
           + D P+DP A
Sbjct: 458 APDAPADPDA 467



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 47/180 (26%), Positives = 65/180 (36%), Gaps = 14/180 (7%)

Query: 178 GEPVDASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEG-RAPGGGLILPGSLTASLEC 236
           G P+  S A  K++R  R     +     +    A+AAEG + P  G   P +  AS + 
Sbjct: 334 GPPIKVSGAPDKRERAER---PPVEEEAAEMEGAADAAEGGKVPSPGYGSPAAGAASADT 390

Query: 237 VKEETPRAAREPEEPSQDAPRDPAGEPAGGEEVPAPADRAPARSCREAEGLAHPGDTGAR 296
                P A  +P+  S   P DP       +   APAD        + +  A P      
Sbjct: 391 AARAAPAAPADPD--SGATPEDP-------DSGTAPADPDSGAFAADPDSGAAPAAPADP 441

Query: 297 GEDAAGHRRAEPGPGEVRTAEDASRTGAVP-VKTVPLVDSEGGSGRAPAAPDPASVDPPS 355
              AA    A+P  G    A      GA P     P       +  APAAPD  +   P+
Sbjct: 442 DSGAAPDAPADPDSGAAPDAPADPDAGAAPEAPAAPAAAETRAAHVAPAAPDAGAPTAPA 501


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 92/388 (23%), Positives = 120/388 (30%), Gaps = 79/388 (20%)

Query: 90  GDGKSSGPTGLVRSRTHDGLAEVLVLESGRKEEPRGGGDSGGGGGGRPNPGPPRAAG-PG 148
           G+    GP G + SR  +G       + G   EP   G+ G  G      G P A G PG
Sbjct: 240 GEPGDPGPMGPIGSRGPEGPPG----KPGEDGEPGRNGNPGEVGFA----GSPGARGFPG 291

Query: 149 GGSLASSSVAKSHSFFSLLKKNGRSENGKGEPVDASKAGGKQKRGLRGLFSGMRWHRKDK 208
              L      + H      K    +   KGE       G     G RG+  G R     +
Sbjct: 292 APGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGM-PGERGRLGPQ 350

Query: 209 RAKAEAAEGRAPG-----GGLILPGS--LTASLECVKEETPRAAREPEEPS----QDAPR 257
            A  +      PG     G L +PGS     +     E  P  AR PE P     +  P 
Sbjct: 351 GAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPP 410

Query: 258 DPAGEPA-----GGEEVPA-------------------PADRAPARSCREAEGLAHPGDT 293
            P G P      G +  P                    P    P  S         PGD 
Sbjct: 411 GPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDP 470

Query: 294 GARGEDAAGHRRAEPGPGEVRTAEDASRTGAVPVKTVPLVDSEGGSGRAPAAPDPASVDP 353
           G  G       + EPGP  ++                  +   G  G+     DP +V P
Sbjct: 471 GVPGFKGEAGPKGEPGPHGIQGP----------------IGPPGEEGKRGPRGDPGTVGP 514

Query: 354 PSDPSADRICLMFSDVTSLKSFDSLTGCGDIIADQEE-----EAGPSCDKHVPG-PGKPA 407
           P  P  +R           + F    G       Q E      +GP   +  PG PG+P 
Sbjct: 515 PG-PVGER------GAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPG 567

Query: 408 LS-----KKNPGVVAYQGGGEEMASPDE 430
           L        NPGV   +G    + +P E
Sbjct: 568 LPGARGLTGNPGVQGPEGKLGPLGAPGE 595



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 89/340 (26%), Positives = 107/340 (31%), Gaps = 31/340 (9%)

Query: 89   KGDGKSSGPTGLVRSRTHDGLAEVLVLESGRKEEPRGGGDSGGGGGGRPNP-GPPRAAGP 147
            KGD  S GP GL  S    G   V  L+ GR  +   G     G  GR  P GP  A GP
Sbjct: 869  KGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGP 928

Query: 148  GG-----GSLASSSVAKSHSFFSLLKKNGRS--ENGKGEPVDASKAGGKQKRGLRGLFSG 200
             G     G      +         +   G +    G G+  D  + G     G  G  +G
Sbjct: 929  AGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGP-AG 987

Query: 201  MRWHRKDKRAKAEAAEGRAPGGGLILPGSLTASLECVKEETPRAAREPEEPSQDAPRDPA 260
                R       +  E   PG    LPG      +            P          P 
Sbjct: 988  TTGQRGIVGMPGQRGERGMPG----LPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPV 1043

Query: 261  GEPAGGEEVPAPADRAPARSCREAEGLAHPGDTGARGEDAAGHRRAEPG-PGEVRTAEDA 319
            GEP  G E PA  D  P R     E     GD G  G       +  PG PG V    DA
Sbjct: 1044 GEP--GPEGPAGNDGTPGRDGAVGER----GDRGDPGPAGLPGSQGAPGTPGPVGAPGDA 1097

Query: 320  SRTGAVPVKTVPLVDSEGGSGRAPAAPDPASVDPPSDPSADRICLMFSDVTSLKSFDSLT 379
             + G  P    P+    G  GRA     P    P  D   D            + F  L 
Sbjct: 1098 GQRGD-PGSRGPI----GPPGRAGKRGLPGPQGPRGD-KGDHGDRGDRGQKGHRGFTGLQ 1151

Query: 380  GCGDIIADQEEEA-----GPSCDKHVPGPGKPALSKKNPG 414
            G         E+      GP   +  PGP  P+  + NPG
Sbjct: 1152 GLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPG 1191



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 65/248 (26%), Positives = 86/248 (34%), Gaps = 31/248 (12%)

Query: 123 PRGGGDSGGGGGGRPNPGPPRAAGPGG--GSLASSSVAKSHSFFSLLKKNGRSENGK-GE 179
           P+G     GG G    PG P   GP G  GS                K     E G+ G 
Sbjct: 223 PQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPG--------KPGEDGEPGRNGN 274

Query: 180 PVDASKAGGKQKRGLRGL--FSGMRWHRKDKRAKAEAAEGRAPGG-GLILPGSLTASLEC 236
           P +   AG    RG  G     G++ HR  K  +    E  APG  G   P   T  +  
Sbjct: 275 PGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGP---TGPMGA 331

Query: 237 VKEETPRAAREPEEPSQDAPRDPAGEPAGGEEVPAPADRAPARSCREAEGLAHPG----- 291
           +    PR    P E  +  P+   G+         P    P      +    +PG     
Sbjct: 332 MGPLGPRGM--PGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEA 389

Query: 292 -DTGARGEDAAGHRRAEPG-PGEVRTAEDASRTGAVPVKTVPLVDSEGGSGRAPAAPDPA 349
             TGARG +    +R E G PG V +       GA+     P   ++G +G    +  P 
Sbjct: 390 GPTGARGPEGPQGQRGETGPPGPVGS---PGLPGAIGTDGTP--GAKGPTGSPGTSGPPG 444

Query: 350 SVDPPSDP 357
           S  PP  P
Sbjct: 445 SAGPPGSP 452



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 79/308 (25%), Positives = 95/308 (30%), Gaps = 58/308 (18%)

Query: 90   GDGKSSGPTGLVRSRTHDGLAEVLVLESGRKEEPRGGGDSGG-------GGGGRPNP-GP 141
            G    +GP GL       G+A       G K +  G G+ G        G  G P P GP
Sbjct: 750  GTPGDTGPPGLQGMPGERGIAGT----PGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGP 805

Query: 142  PRAAGPGGGSLASSSVAKSHSFFSLLKKNGRSENG-------------------KGEPVD 182
            P  AGP G               S      R ENG                   KGEP +
Sbjct: 806  PGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGE 865

Query: 183  ASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEG-RAPGGGLILPGSLTASLECVKEET 241
              + G     G +GL      H  +     +   G + P G    PGS            
Sbjct: 866  PGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGA 925

Query: 242  PRAAREPEEPSQDAP---------------RDPAGEPAG-GEEVPAPADRAPARSCREAE 285
            P  A    EP ++ P               R PAG P G G++     D  P       +
Sbjct: 926  PGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPG-----PD 980

Query: 286  GLAHP-GDTGARGEDAAGHRRAEPG----PGEVRTAEDASRTGAVPVKTVPLVDSEGGSG 340
            G   P G TG RG      +R E G    PG   T      TGA   K  P      GS 
Sbjct: 981  GPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSN 1040

Query: 341  RAPAAPDP 348
                 P P
Sbjct: 1041 GPVGEPGP 1048



 Score = 38.5 bits (88), Expect = 0.020
 Identities = 66/286 (23%), Positives = 90/286 (31%), Gaps = 35/286 (12%)

Query: 96  GPTGLVRSRTHDGLAEVLVLESGRKEEPRGGGDSGGGGGGRPNPGPPRAAGPGG--GSLA 153
           GP GL   R   G       +      P G    GG  G +  PG P A GP G  G   
Sbjct: 657 GPPGLAGERGEQGPPGPTGFQG--LPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERG 714

Query: 154 SSSVAKSHSFFSLLKKNGRS-----ENGKGEPVDASKAGGKQKRGLRGL-----FSGMRW 203
           +           L  + G +     +  KG P  +   G     GL+G+      +G   
Sbjct: 715 NPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPG 774

Query: 204 HRKDKRAKAE-AAEGRAPGGGLI-LPGSLTASLECVKEETPRAAREPEEPSQDAPRDPAG 261
            + D+    E  AEG A   G   LPG L           P  A    E  +  PR   G
Sbjct: 775 PKGDRGGIGEKGAEGTAGNDGARGLPGPL---------GPPGPAGPTGEKGEPGPRGLVG 825

Query: 262 EPAGGEEVPAPADRAPARSCREAEGLAHPGDTGARGEDAAGHRRAE---PGPGEVRTAED 318
            P       +  +  P  +   A      G  G +GE     ++ +   PGP  +  +  
Sbjct: 826 PPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPG 885

Query: 319 ASRTGAVP-------VKTVPLVDSEGGSGRAPAAPDPASVDPPSDP 357
                 VP        +  P      GS      P PA    P+ P
Sbjct: 886 PHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGP 931


>gi|169204930 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 373

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 48/172 (27%), Positives = 62/172 (36%), Gaps = 28/172 (16%)

Query: 73  KRKSGGTMPSIFGVKNKGDGKSSGPTGLVRSRTHDGLAEVLVLESGRKEEP--RGGGDSG 130
           KR+  G  P     +  G G   G     R     G   + V + G       RGGG   
Sbjct: 146 KRRGWGLRPQRVRSRLAGLGAPRGGAAAPRGWGGQGAERLGVHQPGLPTHAALRGGGGGS 205

Query: 131 GGGGGRPNPGPPRAAGPGGGSLASSSV-----AKSHSFFSLLKKNGR----------SEN 175
            GGGG   P PPRA  P  G            A+ H+  + L ++G+          S  
Sbjct: 206 EGGGGGARPSPPRARQPPSGRPRPRRTRLLGSAERHTGRAALARHGQLSRPHAAVRNSSR 265

Query: 176 GKGEPVDASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEGR-----APGG 222
           G+G     S A    + G RG        R D RA+   A+ R     APGG
Sbjct: 266 GRGAATSVSAAARPTRGGARG------HRRADGRARGGCAQLRAGTPSAPGG 311


>gi|239750393 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 373

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 48/172 (27%), Positives = 62/172 (36%), Gaps = 28/172 (16%)

Query: 73  KRKSGGTMPSIFGVKNKGDGKSSGPTGLVRSRTHDGLAEVLVLESGRKEEP--RGGGDSG 130
           KR+  G  P     +  G G   G     R     G   + V + G       RGGG   
Sbjct: 146 KRRGWGLRPQRVRSRLAGLGAPRGGAAAPRGWGGQGAERLGVHQPGLPTHAALRGGGGGS 205

Query: 131 GGGGGRPNPGPPRAAGPGGGSLASSSV-----AKSHSFFSLLKKNGR----------SEN 175
            GGGG   P PPRA  P  G            A+ H+  + L ++G+          S  
Sbjct: 206 EGGGGGARPSPPRARQPPSGRPRPRRTRLLGSAERHTGRAALARHGQLSRPHAAVRNSSR 265

Query: 176 GKGEPVDASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEGR-----APGG 222
           G+G     S A    + G RG        R D RA+   A+ R     APGG
Sbjct: 266 GRGAATSVSAAARPTRGGARG------HRRADGRARGGCAQLRAGTPSAPGG 311


>gi|239744694 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 373

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 48/172 (27%), Positives = 62/172 (36%), Gaps = 28/172 (16%)

Query: 73  KRKSGGTMPSIFGVKNKGDGKSSGPTGLVRSRTHDGLAEVLVLESGRKEEP--RGGGDSG 130
           KR+  G  P     +  G G   G     R     G   + V + G       RGGG   
Sbjct: 146 KRRGWGLRPQRVRSRLAGLGAPRGGAAAPRGWGGQGAERLGVHQPGLPTHAALRGGGGGS 205

Query: 131 GGGGGRPNPGPPRAAGPGGGSLASSSV-----AKSHSFFSLLKKNGR----------SEN 175
            GGGG   P PPRA  P  G            A+ H+  + L ++G+          S  
Sbjct: 206 EGGGGGARPSPPRARQPPSGRPRPRRTRLLGSAERHTGRAALARHGQLSRPHAAVRNSSR 265

Query: 176 GKGEPVDASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEGR-----APGG 222
           G+G     S A    + G RG        R D RA+   A+ R     APGG
Sbjct: 266 GRGAATSVSAAARPTRGGARG------HRRADGRARGGCAQLRAGTPSAPGG 311


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.308    0.130    0.381 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,060,789
Number of Sequences: 37866
Number of extensions: 2282083
Number of successful extensions: 18789
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 151
Number of HSP's successfully gapped in prelim test: 974
Number of HSP's that attempted gapping in prelim test: 12707
Number of HSP's gapped (non-prelim): 5072
length of query: 671
length of database: 18,247,518
effective HSP length: 109
effective length of query: 562
effective length of database: 14,120,124
effective search space: 7935509688
effective search space used: 7935509688
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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