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Search of human proteins with 40255052
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40255052 IQ motif containing with AAA domain 1 [Homo
sapiens]
(822 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40255052 IQ motif containing with AAA domain 1 [Homo sapiens] 1628 0.0
gi|40806170 spastin isoform 2 [Homo sapiens] 97 5e-20
gi|11875211 spastin isoform 1 [Homo sapiens] 97 5e-20
gi|64084766 fidgetin [Homo sapiens] 86 1e-16
gi|31742536 fidgetin-like 1 [Homo sapiens] 75 3e-13
gi|112789543 fidgetin-like 1 [Homo sapiens] 75 3e-13
gi|7019569 vacuolar protein sorting factor 4A [Homo sapiens] 72 2e-12
gi|17865802 vacuolar protein sorting factor 4B [Homo sapiens] 70 1e-11
gi|226371754 katanin p60 subunit A-like 2 [Homo sapiens] 69 2e-11
gi|5901990 katanin p60 subunit A 1 [Homo sapiens] 69 2e-11
gi|62177112 katanin p60 subunit A-like 1 [Homo sapiens] 69 2e-11
gi|14149767 katanin p60 subunit A-like 1 [Homo sapiens] 69 2e-11
gi|229577436 spermatogenesis associated 5-like 1 [Homo sapiens] 61 4e-09
gi|31377644 ATPase family, AAA domain containing 1 [Homo sapiens] 60 6e-09
gi|157671927 spermatogenesis associated 5 [Homo sapiens] 59 1e-08
gi|148746195 trichohyalin [Homo sapiens] 59 2e-08
gi|195539395 proteasome 26S ATPase subunit 6 [Homo sapiens] 59 2e-08
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 58 4e-08
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 56 2e-07
gi|6005942 valosin-containing protein [Homo sapiens] 55 2e-07
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 55 3e-07
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 54 5e-07
gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens] 54 8e-07
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 53 1e-06
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 53 1e-06
gi|45643125 nuclear VCP-like isoform 2 [Homo sapiens] 53 1e-06
gi|45643123 nuclear VCP-like isoform 1 [Homo sapiens] 53 1e-06
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 53 1e-06
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 53 1e-06
gi|21327685 YME1-like 1 isoform 1 [Homo sapiens] 53 1e-06
>gi|40255052 IQ motif containing with AAA domain 1 [Homo sapiens]
Length = 822
Score = 1628 bits (4217), Expect = 0.0
Identities = 822/822 (100%), Positives = 822/822 (100%)
Query: 1 MSNAMYNKMWHQTQEALGALLDKEPQKMIEPQRNQVFIFQTLATFYVKYVQIFRNLENVY 60
MSNAMYNKMWHQTQEALGALLDKEPQKMIEPQRNQVFIFQTLATFYVKYVQIFRNLENVY
Sbjct: 1 MSNAMYNKMWHQTQEALGALLDKEPQKMIEPQRNQVFIFQTLATFYVKYVQIFRNLENVY 60
Query: 61 DQFVHPQKRILIRKVLDGVMGRILELKNEMVELELTEFHYFDDILQDLKLAPQQLDIPIP 120
DQFVHPQKRILIRKVLDGVMGRILELKNEMVELELTEFHYFDDILQDLKLAPQQLDIPIP
Sbjct: 61 DQFVHPQKRILIRKVLDGVMGRILELKNEMVELELTEFHYFDDILQDLKLAPQQLDIPIP 120
Query: 121 KYFLKEKLEVIKGREKILAQILADSGIDTSDMKYPVKSIPFDEAVKLIQIAERARQGRLR 180
KYFLKEKLEVIKGREKILAQILADSGIDTSDMKYPVKSIPFDEAVKLIQIAERARQGRLR
Sbjct: 121 KYFLKEKLEVIKGREKILAQILADSGIDTSDMKYPVKSIPFDEAVKLIQIAERARQGRLR 180
Query: 181 ALFMKQIYLQEYRAKQSKMLGKKVTDTWAAALRIQKVWRRFHQRKETEKLREEEMIFLGM 240
ALFMKQIYLQEYRAKQSKMLGKKVTDTWAAALRIQKVWRRFHQRKETEKLREEEMIFLGM
Sbjct: 181 ALFMKQIYLQEYRAKQSKMLGKKVTDTWAAALRIQKVWRRFHQRKETEKLREEEMIFLGM 240
Query: 241 NPPPLFNEVSATVIQAEKVDRLRNEVQIKHEEDYREALVTIKNDLKLIEGVDIKENLQDQ 300
NPPPLFNEVSATVIQAEKVDRLRNEVQIKHEEDYREALVTIKNDLKLIEGVDIKENLQDQ
Sbjct: 241 NPPPLFNEVSATVIQAEKVDRLRNEVQIKHEEDYREALVTIKNDLKLIEGVDIKENLQDQ 300
Query: 301 IRHWFIECRNLTGTFPDYPDVEEGGSAIIFSDKTIQQVIEDIIANQEEEEKNKKKKKKKE 360
IRHWFIECRNLTGTFPDYPDVEEGGSAIIFSDKTIQQVIEDIIANQEEEEKNKKKKKKKE
Sbjct: 301 IRHWFIECRNLTGTFPDYPDVEEGGSAIIFSDKTIQQVIEDIIANQEEEEKNKKKKKKKE 360
Query: 361 KQPKKAKKQKKGTKEKNKEEDEKWKMSPSLFLPAMKEGCNAYKEIWMKKDESWNFSQDYD 420
KQPKKAKKQKKGTKEKNKEEDEKWKMSPSLFLPAMKEGCNAYKEIWMKKDESWNFSQDYD
Sbjct: 361 KQPKKAKKQKKGTKEKNKEEDEKWKMSPSLFLPAMKEGCNAYKEIWMKKDESWNFSQDYD 420
Query: 421 PELIKEEKRKELQSEIRIQVDELMRQELKNLKLAVDRERERPVKAGKKKDKKGKKGKKKE 480
PELIKEEKRKELQSEIRIQVDELMRQELKNLKLAVDRERERPVKAGKKKDKKGKKGKKKE
Sbjct: 421 PELIKEEKRKELQSEIRIQVDELMRQELKNLKLAVDRERERPVKAGKKKDKKGKKGKKKE 480
Query: 481 KKAKKDKDLTADRTIESLYKELVEEGLLIQALKVNLSDYIGEYSYLGTTLRQVSIEPMPS 540
KKAKKDKDLTADRTIESLYKELVEEGLLIQALKVNLSDYIGEYSYLGTTLRQVSIEPMPS
Sbjct: 481 KKAKKDKDLTADRTIESLYKELVEEGLLIQALKVNLSDYIGEYSYLGTTLRQVSIEPMPS 540
Query: 541 LLDVRQLITLYGIWPLGSAAVHEKAPLVKSLLLAGPSGVGKKMLVHAICTETGANLFNLS 600
LLDVRQLITLYGIWPLGSAAVHEKAPLVKSLLLAGPSGVGKKMLVHAICTETGANLFNLS
Sbjct: 541 LLDVRQLITLYGIWPLGSAAVHEKAPLVKSLLLAGPSGVGKKMLVHAICTETGANLFNLS 600
Query: 601 SSNIAGKYPGKNGLQMMLHAVFKVARQLQPSVVWIEDTEKTFYKKVPNAEKMNEPKRLKK 660
SSNIAGKYPGKNGLQMMLHAVFKVARQLQPSVVWIEDTEKTFYKKVPNAEKMNEPKRLKK
Sbjct: 601 SSNIAGKYPGKNGLQMMLHAVFKVARQLQPSVVWIEDTEKTFYKKVPNAEKMNEPKRLKK 660
Query: 661 HLPQILKLLKPDDRILIVGTTRRPFDAELQSFCKVYQKIILVPRPDYASRYVLWKQIIER 720
HLPQILKLLKPDDRILIVGTTRRPFDAELQSFCKVYQKIILVPRPDYASRYVLWKQIIER
Sbjct: 661 HLPQILKLLKPDDRILIVGTTRRPFDAELQSFCKVYQKIILVPRPDYASRYVLWKQIIER 720
Query: 721 NGGVLTSALNVSCLAKVTDGFTQGHIVEVVKGVLTDQRIRRQIHKPLTAVEFITAITSMN 780
NGGVLTSALNVSCLAKVTDGFTQGHIVEVVKGVLTDQRIRRQIHKPLTAVEFITAITSMN
Sbjct: 721 NGGVLTSALNVSCLAKVTDGFTQGHIVEVVKGVLTDQRIRRQIHKPLTAVEFITAITSMN 780
Query: 781 PVYKEEEESFKNWYAKTPLGKKRALAITGGSTEKAKDKGKRK 822
PVYKEEEESFKNWYAKTPLGKKRALAITGGSTEKAKDKGKRK
Sbjct: 781 PVYKEEEESFKNWYAKTPLGKKRALAITGGSTEKAKDKGKRK 822
>gi|40806170 spastin isoform 2 [Homo sapiens]
Length = 584
Score = 97.4 bits (241), Expect = 5e-20
Identities = 78/288 (27%), Positives = 144/288 (50%), Gaps = 26/288 (9%)
Query: 466 GKKKDKKGKKGKKKEKKAKKDKDLTADRTIESLYKELVEEGLLIQALKVNLSDYIGEYSY 525
G K + K +K KDL R ++S L+ ++ V D G+
Sbjct: 259 GTPKTNRTNKPSTPTTATRKKKDLKNFRNVDSNLANLIMNEIVDNGTAVKFDDIAGQ-DL 317
Query: 526 LGTTLRQVSIEPMPSLLDVRQLITLYGIWPLGSAAVHEKAPLVKSLLLAGPSGVGKKMLV 585
L+++ I +PSL +L T G+ +AP + LLL GP G GK ML
Sbjct: 318 AKQALQEIVI--LPSLRP--ELFT--GL----------RAP-ARGLLLFGPPGNGKTMLA 360
Query: 586 HAICTETGANLFNLSSSNIAGKYPGKNGLQMMLHAVFKVARQLQPSVVWIEDTEKTFYKK 645
A+ E+ A FN+S++++ KY G+ + ++ A+F VAR+LQPS+++I++ + ++
Sbjct: 361 KAVAAESNATFFNISAASLTSKYVGEG--EKLVRALFAVARELQPSIIFIDEVDSLLCER 418
Query: 646 VPNAEKMNEPKRLKKHLPQILKLLKP--DDRILIVGTTRRPFDAELQSFCKVYQKIILVP 703
+ + +RLK ++ DDR+L++G T RP + + ++ + + K + V
Sbjct: 419 --REGEHDASRRLKTEFLIEFDGVQSAGDDRVLVMGATNRPQELD-EAVLRRFIKRVYVS 475
Query: 704 RPDYASRYVLWKQIIERNGGVLTSALNVSCLAKVTDGFTQGHIVEVVK 751
P+ +R +L K ++ + G LT ++ LA++TDG++ + + K
Sbjct: 476 LPNEETRLLLLKNLLCKQGSPLTQK-ELAQLARMTDGYSGSDLTALAK 522
>gi|11875211 spastin isoform 1 [Homo sapiens]
Length = 616
Score = 97.4 bits (241), Expect = 5e-20
Identities = 78/288 (27%), Positives = 144/288 (50%), Gaps = 26/288 (9%)
Query: 466 GKKKDKKGKKGKKKEKKAKKDKDLTADRTIESLYKELVEEGLLIQALKVNLSDYIGEYSY 525
G K + K +K KDL R ++S L+ ++ V D G+
Sbjct: 291 GTPKTNRTNKPSTPTTATRKKKDLKNFRNVDSNLANLIMNEIVDNGTAVKFDDIAGQ-DL 349
Query: 526 LGTTLRQVSIEPMPSLLDVRQLITLYGIWPLGSAAVHEKAPLVKSLLLAGPSGVGKKMLV 585
L+++ I +PSL +L T G+ +AP + LLL GP G GK ML
Sbjct: 350 AKQALQEIVI--LPSLRP--ELFT--GL----------RAP-ARGLLLFGPPGNGKTMLA 392
Query: 586 HAICTETGANLFNLSSSNIAGKYPGKNGLQMMLHAVFKVARQLQPSVVWIEDTEKTFYKK 645
A+ E+ A FN+S++++ KY G+ + ++ A+F VAR+LQPS+++I++ + ++
Sbjct: 393 KAVAAESNATFFNISAASLTSKYVGEG--EKLVRALFAVARELQPSIIFIDEVDSLLCER 450
Query: 646 VPNAEKMNEPKRLKKHLPQILKLLKP--DDRILIVGTTRRPFDAELQSFCKVYQKIILVP 703
+ + +RLK ++ DDR+L++G T RP + + ++ + + K + V
Sbjct: 451 --REGEHDASRRLKTEFLIEFDGVQSAGDDRVLVMGATNRPQELD-EAVLRRFIKRVYVS 507
Query: 704 RPDYASRYVLWKQIIERNGGVLTSALNVSCLAKVTDGFTQGHIVEVVK 751
P+ +R +L K ++ + G LT ++ LA++TDG++ + + K
Sbjct: 508 LPNEETRLLLLKNLLCKQGSPLTQK-ELAQLARMTDGYSGSDLTALAK 554
>gi|64084766 fidgetin [Homo sapiens]
Length = 759
Score = 85.9 bits (211), Expect = 1e-16
Identities = 72/263 (27%), Positives = 130/263 (49%), Gaps = 18/263 (6%)
Query: 544 VRQLITLYGIWP-LGSAAVHEKAPLVKSLLLAGPSGVGKKMLVHAICTETGANLFNLSSS 602
V+ +I +WP L S A L +S+LL GP G GK +L I ++ GA F ++ S
Sbjct: 494 VKAVIKEEVLWPVLRSDAFSGLTALPRSILLFGPRGTGKTLLGRCIASQLGATFFKIAGS 553
Query: 603 NIAGKYPGKNGLQMMLHAVFKVARQLQPSVVWIEDTEKTFYKKVPNAEKMNEPKRLKKHL 662
+ K+ G+ + ++HA F VAR QPSV+++ D + +V N E + + L
Sbjct: 554 GLVAKWLGE--AEKIIHASFLVARCRQPSVIFVSDIDMLLSSQV-NEEHSPVSRMRTEFL 610
Query: 663 PQI-LKLLKPDDRILIVGTTRRPFDAELQSFCKVYQKIILVPRPDYASRYVLWKQIIERN 721
Q+ L +D+I+++ T +P + + +S + + K +L+P PD +R+ + Q++ ++
Sbjct: 611 MQLDTVLTSAEDQIVVICATSKPEEID-ESLRRYFMKRLLIPLPDSTARHQIIVQLLSQH 669
Query: 722 GGVLTSALNVSCLAKVTDGFTQGHIV----EVVKGVL-----TD-QRIRRQIHKPLTAVE 771
L + L + T+GF+ + E V G L TD I +P+T +
Sbjct: 670 NYCLNDK-EFALLVQRTEGFSGLDVAHLCQEAVVGPLHAMPATDLSAIMPSQLRPVTYQD 728
Query: 772 FITAITSMNP-VYKEEEESFKNW 793
F A + P + ++E + + W
Sbjct: 729 FENAFCKIQPSISQKELDMYVEW 751
>gi|31742536 fidgetin-like 1 [Homo sapiens]
Length = 674
Score = 74.7 bits (182), Expect = 3e-13
Identities = 58/251 (23%), Positives = 123/251 (49%), Gaps = 29/251 (11%)
Query: 569 KSLLLAGPSGVGKKMLVHAICTETGANLFNLSSSNIAGKYPGKNGLQMMLHAVFKVARQL 628
K +LL GP G GK ++ I +++GA F++S+S++ K+ G+ + M+ A+F VAR
Sbjct: 435 KGILLFGPPGTGKTLIGKCIASQSGATFFSISASSLTSKWVGEG--EKMVRALFAVARCQ 492
Query: 629 QPSVVWIEDTEKTFYKKVPNAEKMNEPKRLKKHLPQIL--KLLKPDDRILIVGTTRRPFD 686
QP+V++I++ + ++ + + +R+K L +DRIL+VG T RP +
Sbjct: 493 QPAVIFIDEIDSLLSQRGDGEHESS--RRIKTEFLVQLDGATTSSEDRILVVGATNRPQE 550
Query: 687 AELQSFCKVYQKIILVPRPDYASRYVLWKQIIERNGGVLTSALNVSCLAKVTDGFTQGHI 746
+ ++ + K + +P P+ ++R + ++ + L S + + + +D F+ +
Sbjct: 551 ID-EAARRRLVKRLYIPLPEASARKQIVINLMSKEQCCL-SEEEIEQIVQQSDAFSGADM 608
Query: 747 VEVVK---------------GVLTDQRIRRQIHKPLTAVEFITAITSMNP-VYKEEEESF 790
++ + +T ++R P+ ++F A ++ P V ++ E +
Sbjct: 609 TQLCREASLGPIRSLQTADIATITPDQVR-----PIAYIDFENAFRTVRPSVSPKDLELY 663
Query: 791 KNWYAKTPLGK 801
+NW GK
Sbjct: 664 ENWNKTFGCGK 674
>gi|112789543 fidgetin-like 1 [Homo sapiens]
Length = 674
Score = 74.7 bits (182), Expect = 3e-13
Identities = 58/251 (23%), Positives = 123/251 (49%), Gaps = 29/251 (11%)
Query: 569 KSLLLAGPSGVGKKMLVHAICTETGANLFNLSSSNIAGKYPGKNGLQMMLHAVFKVARQL 628
K +LL GP G GK ++ I +++GA F++S+S++ K+ G+ + M+ A+F VAR
Sbjct: 435 KGILLFGPPGTGKTLIGKCIASQSGATFFSISASSLTSKWVGEG--EKMVRALFAVARCQ 492
Query: 629 QPSVVWIEDTEKTFYKKVPNAEKMNEPKRLKKHLPQIL--KLLKPDDRILIVGTTRRPFD 686
QP+V++I++ + ++ + + +R+K L +DRIL+VG T RP +
Sbjct: 493 QPAVIFIDEIDSLLSQRGDGEHESS--RRIKTEFLVQLDGATTSSEDRILVVGATNRPQE 550
Query: 687 AELQSFCKVYQKIILVPRPDYASRYVLWKQIIERNGGVLTSALNVSCLAKVTDGFTQGHI 746
+ ++ + K + +P P+ ++R + ++ + L S + + + +D F+ +
Sbjct: 551 ID-EAARRRLVKRLYIPLPEASARKQIVINLMSKEQCCL-SEEEIEQIVQQSDAFSGADM 608
Query: 747 VEVVK---------------GVLTDQRIRRQIHKPLTAVEFITAITSMNP-VYKEEEESF 790
++ + +T ++R P+ ++F A ++ P V ++ E +
Sbjct: 609 TQLCREASLGPIRSLQTADIATITPDQVR-----PIAYIDFENAFRTVRPSVSPKDLELY 663
Query: 791 KNWYAKTPLGK 801
+NW GK
Sbjct: 664 ENWNKTFGCGK 674
>gi|7019569 vacuolar protein sorting factor 4A [Homo sapiens]
Length = 437
Score = 72.4 bits (176), Expect = 2e-12
Identities = 70/294 (23%), Positives = 142/294 (48%), Gaps = 32/294 (10%)
Query: 467 KKKDKKGKKGKKKEKKAKK--DKDLTADRTIESLYKELVEEGLLIQALKVNLSDYIGEYS 524
+ K+K GKK K+ + K D D D + +E + ++++ + +D G
Sbjct: 75 RSKEKHGKKPVKENQSEGKGSDSDSEGDNPEKKKLQEQLMGAVVMEKPNIRWNDVAG-LE 133
Query: 525 YLGTTLRQVSIEPM--PSLLDVRQLITLYGIWPLGSAAVHEKAPLVKSLLLAGPSGVGKK 582
L++ I P+ P L ++ W + +LL GP G GK
Sbjct: 134 GAKEALKEAVILPIKFPHLFTGKRTP-----W--------------RGILLFGPPGTGKS 174
Query: 583 MLVHAICTE-TGANLFNLSSSNIAGKYPGKNGLQMMLHAVFKVARQLQPSVVWIEDTEKT 641
L A+ TE + F++SSS++ K+ G++ + ++ +F++ARQ +PS+++I++ +
Sbjct: 175 YLAKAVATEANNSTFFSVSSSDLMSKWLGES--EKLVKNLFELARQHKPSIIFIDEVDSL 232
Query: 642 FYKKVPNAEKMNEPKRLK-KHLPQILKLLKPDDRILIVGTTRRPFDAELQSFCKVYQKII 700
+ N + +R+K + L Q+ + +D L++G T P+ + + + ++K I
Sbjct: 233 CGSR--NENESEAARRIKTEFLVQMQGVGNNNDGTLVLGATNIPWVLD-SAIRRRFEKRI 289
Query: 701 LVPRPDYASRYVLWKQIIERNGGVLTSALNVSCLAKVTDGFTQGHIVEVVKGVL 754
+P P+ A+R +++ + LT A N+ LA+ T+G++ I +V+ L
Sbjct: 290 YIPLPEEAARAQMFRLHLGSTPHNLTDA-NIHELARKTEGYSGADISIIVRDSL 342
>gi|17865802 vacuolar protein sorting factor 4B [Homo sapiens]
Length = 444
Score = 69.7 bits (169), Expect = 1e-11
Identities = 50/188 (26%), Positives = 103/188 (54%), Gaps = 8/188 (4%)
Query: 569 KSLLLAGPSGVGKKMLVHAICTE-TGANLFNLSSSNIAGKYPGKNGLQMMLHAVFKVARQ 627
+ +LL GP G GK L A+ TE + F++SSS++ K+ G++ + ++ +F++AR+
Sbjct: 168 RGILLFGPPGTGKSYLAKAVATEANNSTFFSISSSDLVSKWLGES--EKLVKNLFQLARE 225
Query: 628 LQPSVVWIEDTEKTFYKKVPNAEKMNEPKRLK-KHLPQILKLLKPDDRILIVGTTRRPFD 686
+PS+++I++ + + N + +R+K + L Q+ + +D IL++G T P+
Sbjct: 226 NKPSIIFIDEIDSLCGSRSEN--ESEAARRIKTEFLVQMQGVGVDNDGILVLGATNIPWV 283
Query: 687 AELQSFCKVYQKIILVPRPDYASRYVLWKQIIERNGGVLTSALNVSCLAKVTDGFTQGHI 746
+ + + ++K I +P P+ +R ++K + LT A + L + TDG++ I
Sbjct: 284 LD-SAIRRRFEKRIYIPLPEPHARAAMFKLHLGTTQNSLTEA-DFRELGRKTDGYSGADI 341
Query: 747 VEVVKGVL 754
+V+ L
Sbjct: 342 SIIVRDAL 349
>gi|226371754 katanin p60 subunit A-like 2 [Homo sapiens]
Length = 466
Score = 68.9 bits (167), Expect = 2e-11
Identities = 55/248 (22%), Positives = 116/248 (46%), Gaps = 27/248 (10%)
Query: 569 KSLLLAGPSGVGKKMLVHAICTETGANLFNLSSSNIAGKYPGKNGLQMMLHAVFKVARQL 628
K LLL GP G GK +L A+ TE FN+S+S I K+ G + + ++ +F++AR
Sbjct: 216 KGLLLYGPPGTGKTLLAKAVATECKTTFFNISASTIVSKWRGDS--EKLVRVLFELARYH 273
Query: 629 QPSVVWIEDTEKTFYKK--VPNAEKMNEPKRLKKHLPQILKLLKPDDRILIVGTTRRPFD 686
PS +++++ E ++ E + + L Q+ L + +D + ++ + P++
Sbjct: 274 APSTIFLDELESVMSQRGTASGGEHEGSLRMKTELLVQMDGLARSEDLVFVLAASNLPWE 333
Query: 687 AELQSFCKVYQKIILVPRPDYASRYVL---WKQIIERNGGV-LTSALNVSCLAKVTDGFT 742
+ + + +K ILV P +R + W + ++ + L + L S L++ T+G++
Sbjct: 334 LDC-AMLRRLEKRILVDLPSREARQAMIYHWLPPVSKSRALELHTELEYSVLSQETEGYS 392
Query: 743 QGHIVEVVKGVLTDQRIRR-----QIHKP------------LTAVEFITAITSMNPVYKE 785
G +++V + +R+ + H+ +T +F+ +T P K
Sbjct: 393 -GSDIKLVCREAAMRPVRKIFDALENHQSESSDLPRIQLDIVTTADFLDVLTHTKPSAKN 451
Query: 786 EEESFKNW 793
+ + +W
Sbjct: 452 LAQRYSDW 459
>gi|5901990 katanin p60 subunit A 1 [Homo sapiens]
Length = 491
Score = 68.9 bits (167), Expect = 2e-11
Identities = 56/248 (22%), Positives = 116/248 (46%), Gaps = 29/248 (11%)
Query: 569 KSLLLAGPSGVGKKMLVHAICTETGANLFNLSSSNIAGKYPGKNGLQMMLHAVFKVARQL 628
K +L+ GP G GK +L A+ TE FN+SSS + KY G++ + ++ +F++AR
Sbjct: 243 KGVLMVGPPGTGKTLLAKAVATECKTTFFNVSSSTLTSKYRGES--EKLVRLLFEMARFY 300
Query: 629 QPSVVWIEDTEKTFYKKVPNAEKMNEPKRLKKHLPQILKLL-------KPDDRILIVGTT 681
P+ ++I++ + ++ +E+ +R+K L + + P ++++ T
Sbjct: 301 SPATIFIDEIDSICSRR-GTSEEHEASRRVKAELLVQMDGVGGTSENDDPSKMVMVLAAT 359
Query: 682 RRPFDAELQSFCKVYQKIILVPRPDYASRYVLWKQIIERNGGVLTSALNVSCLAKVTDGF 741
P+D + ++ + +K I +P P R L + I L ++++ +A+ +G+
Sbjct: 360 NFPWDID-EALRRRLEKRIYIPLPSAKGREELLR--ISLRELELADDVDLASIAENMEGY 416
Query: 742 TQGHIVEVVKGV-----------LTDQRIR----RQIHKPLTAVEFITAITSMN-PVYKE 785
+ I V + LT + IR ++H P T +F A+ ++ V
Sbjct: 417 SGADITNVCRDASLMAMRRRIEGLTPEEIRNLSKEEMHMPTTMEDFEMALKKVSKSVSAA 476
Query: 786 EEESFKNW 793
+ E ++ W
Sbjct: 477 DIERYEKW 484
>gi|62177112 katanin p60 subunit A-like 1 [Homo sapiens]
Length = 490
Score = 68.9 bits (167), Expect = 2e-11
Identities = 57/248 (22%), Positives = 114/248 (45%), Gaps = 29/248 (11%)
Query: 569 KSLLLAGPSGVGKKMLVHAICTETGANLFNLSSSNIAGKYPGKNGLQMMLHAVFKVARQL 628
K +L+ GP G GK ML A+ TE G FN+SSS + KY G++ + ++ +F++AR
Sbjct: 242 KGVLMVGPPGTGKTMLAKAVATECGTTFFNVSSSTLTSKYRGES--EKLVRLLFEMARFY 299
Query: 629 QPSVVWIEDTEKTFYKKVPNAEKMNEPKRLKKHL-------PQILKLLKPDDRILIVGTT 681
P+ ++I++ + ++ +++ +R+K L L+ P ++++ T
Sbjct: 300 APTTIFIDEIDSICSRR-GTSDEHEASRRVKSELLIQMDGVGGALENDDPSKMVMVLAAT 358
Query: 682 RRPFDAELQSFCKVYQKIILVPRPDYASRYVLWKQIIERNGGVLTSALNVSCLAKVTDGF 741
P+D + ++ + +K I +P P R L K I L + + +A+ +G+
Sbjct: 359 NFPWDID-EALRRRLEKRIYIPLPTAKGRAELLK--INLREVELDPDIQLEDIAEKIEGY 415
Query: 742 TQGHIVEVVKGV-----------LTDQRIR----RQIHKPLTAVEFITAITSM-NPVYKE 785
+ I V + L+ + IR ++ P+T +F A+ + V
Sbjct: 416 SGADITNVCRDASLMAMRRRINGLSPEEIRALSKEELQMPVTKGDFELALKKIAKSVSAA 475
Query: 786 EEESFKNW 793
+ E ++ W
Sbjct: 476 DLEKYEKW 483
>gi|14149767 katanin p60 subunit A-like 1 [Homo sapiens]
Length = 490
Score = 68.9 bits (167), Expect = 2e-11
Identities = 57/248 (22%), Positives = 114/248 (45%), Gaps = 29/248 (11%)
Query: 569 KSLLLAGPSGVGKKMLVHAICTETGANLFNLSSSNIAGKYPGKNGLQMMLHAVFKVARQL 628
K +L+ GP G GK ML A+ TE G FN+SSS + KY G++ + ++ +F++AR
Sbjct: 242 KGVLMVGPPGTGKTMLAKAVATECGTTFFNVSSSTLTSKYRGES--EKLVRLLFEMARFY 299
Query: 629 QPSVVWIEDTEKTFYKKVPNAEKMNEPKRLKKHL-------PQILKLLKPDDRILIVGTT 681
P+ ++I++ + ++ +++ +R+K L L+ P ++++ T
Sbjct: 300 APTTIFIDEIDSICSRR-GTSDEHEASRRVKSELLIQMDGVGGALENDDPSKMVMVLAAT 358
Query: 682 RRPFDAELQSFCKVYQKIILVPRPDYASRYVLWKQIIERNGGVLTSALNVSCLAKVTDGF 741
P+D + ++ + +K I +P P R L K I L + + +A+ +G+
Sbjct: 359 NFPWDID-EALRRRLEKRIYIPLPTAKGRAELLK--INLREVELDPDIQLEDIAEKIEGY 415
Query: 742 TQGHIVEVVKGV-----------LTDQRIR----RQIHKPLTAVEFITAITSM-NPVYKE 785
+ I V + L+ + IR ++ P+T +F A+ + V
Sbjct: 416 SGADITNVCRDASLMAMRRRINGLSPEEIRALSKEELQMPVTKGDFELALKKIAKSVSAA 475
Query: 786 EEESFKNW 793
+ E ++ W
Sbjct: 476 DLEKYEKW 483
>gi|229577436 spermatogenesis associated 5-like 1 [Homo sapiens]
Length = 753
Score = 61.2 bits (147), Expect = 4e-09
Identities = 58/249 (23%), Positives = 120/249 (48%), Gaps = 25/249 (10%)
Query: 544 VRQLITLYGIWPLGSAAVHEKAPLVKSLLLAGPSGVGKKMLVHAICTETGANLFNLSSSN 603
+R+L+ L +P A+ P + +LLAGP GVGK LV A+ E GA L +S+
Sbjct: 212 LRELLRLPLRYPRALTALGLAVP--RGVLLAGPPGVGKTQLVRAVAREAGAELLAVSAPA 269
Query: 604 IAGKYPGKNGLQMMLHAVFKVARQLQ---PSVVWIEDTEKTFYKKVPNAEKMNEPKRLKK 660
+ G PG+ + + VF+ AR+L PS++++++ + ++ A + +
Sbjct: 270 LQGSRPGET--EENVRRVFQRARELASRGPSLLFLDEMDALCPQRGSRAPE-------SR 320
Query: 661 HLPQILKLL---KPDDRILIVGTTRRP--FDAELQSFCKVYQKIILVPRPDYASRYVLWK 715
+ Q+L LL D +++VG T RP D L+ + + + +++ P R + +
Sbjct: 321 VVAQVLTLLDGASGDREVVVVGATNRPDALDPALRRPGR-FDREVVIGTPTLKQRKEILQ 379
Query: 716 QIIERNGGVLTSALNVSCLAKVTDGFTQGHIVEVVKGVLTDQRI---RRQIHKPLTAVEF 772
I + ++S +++ LA++T G+ + + + + + Q + + ++F
Sbjct: 380 VITSKM--PISSHVDLGLLAEMTVGYVGADLTALCREAAMHALLHSEKNQDNPVIDEIDF 437
Query: 773 ITAITSMNP 781
+ A ++ P
Sbjct: 438 LEAFKNIQP 446
>gi|31377644 ATPase family, AAA domain containing 1 [Homo sapiens]
Length = 361
Score = 60.5 bits (145), Expect = 6e-09
Identities = 56/272 (20%), Positives = 126/272 (46%), Gaps = 17/272 (6%)
Query: 485 KDKDLTADRTIESLYKELVEEGLLIQALKVNLSDYIGEYSYLGTTLRQVSIEPMPSLLDV 544
+ + + A + E L K++ + + + +++++ ++ + + T ++ L DV
Sbjct: 45 RKQKVEAQKQAEKLMKQIGVKNVKLSEYEMSIAAHLVDPLNMHVTWSDIA-----GLDDV 99
Query: 545 RQLITLYGIWPLGSAAVHEKAPLV---KSLLLAGPSGVGKKMLVHAICTETGANLFNLSS 601
+ I P+ + E + L+ K +LL GP G GK ++ A E G NL
Sbjct: 100 ITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKTLIAKATAKEAGCRFINLQP 159
Query: 602 SNIAGKYPGKNGLQMMLHAVFKVARQLQPSVVWIEDTEKTFYKKVPNAEKMNEPKRLKKH 661
S + K+ G++ Q + AVF +A +LQPS+++I++ + + + ++ +K
Sbjct: 160 STLTDKWYGES--QKLAAAVFSLAIKLQPSIIFIDEIDS--FLRNRSSSDHEATAMMKAQ 215
Query: 662 LPQILKLLKPDD--RILIVGTTRRPFDAELQSFCKVYQKIILVPRPDYASRYVLWKQIIE 719
+ L D +++++G T RP D + + + + +P R + K I++
Sbjct: 216 FMSLWDGLDTDHSCQVIVMGATNRPQDLD-SAIMRRMPTRFHINQPALKQREAILKLILK 274
Query: 720 RNGGVLTSALNVSCLAKVTDGFTQGHIVEVVK 751
+ +++ +A+ TDGF+ + E+ +
Sbjct: 275 NEN--VDRHVDLLEVAQETDGFSGSDLKEMCR 304
>gi|157671927 spermatogenesis associated 5 [Homo sapiens]
Length = 893
Score = 59.3 bits (142), Expect = 1e-08
Identities = 44/185 (23%), Positives = 89/185 (48%), Gaps = 7/185 (3%)
Query: 569 KSLLLAGPSGVGKKMLVHAICTETGANLFNLSSSNIAGKYPGKNGLQMMLHAVFKVARQL 628
K +LL GP G K M+ A+ E+G N + + KY G++ + + F+ AR +
Sbjct: 662 KGVLLYGPPGCSKTMIAKALANESGLNFLAIKGPELMNKYVGES--ERAVRETFRKARAV 719
Query: 629 QPSVVWIEDTEKTFYKKVPNAEKMNEPKRLKKHLPQILKLLKPDDRILIVGTTRRP--FD 686
PS+++ ++ + ++ + N R+ L + ++ + I+ T RP D
Sbjct: 720 APSIIFFDELDALAVERGSSLGAGNVADRVLAQLLTEMDGIEQLKDVTILAATNRPDRID 779
Query: 687 AELQSFCKVYQKIILVPRPDYASRYVLWKQIIERNGGVLTSALNVSCLAKVTDGFTQGHI 746
L ++ +II VP PD A+R ++K ++ + +++ +++ L TD ++ I
Sbjct: 780 KALMRPGRI-DRIIYVPLPDAATRREIFK--LQFHSMPVSNEVDLDELILQTDAYSGAEI 836
Query: 747 VEVVK 751
V V +
Sbjct: 837 VAVCR 841
Score = 52.8 bits (125), Expect = 1e-06
Identities = 42/171 (24%), Positives = 82/171 (47%), Gaps = 16/171 (9%)
Query: 566 PLVKSLLLAGPSGVGKKMLVHAICTETGANLFNLSSSNIAGKYPGKNGLQMMLHAVFKVA 625
P + +LL GP G GK M+ A+ E GA + ++ I K+ G+ + L +F A
Sbjct: 385 PAPRGVLLYGPPGTGKTMIARAVANEVGAYVSVINGPEIISKFYGET--EAKLRQIFAEA 442
Query: 626 RQLQPSVVWIEDTEKTFYKKVPNAEKMNEPKRLKKHLPQILKLLK------PDDRILIVG 679
PS+++I++ + K+ ++ K+ + +L L+ + ++L++G
Sbjct: 443 TLRHPSIIFIDELDALCPKREGAQNEVE-----KRVVASLLTLMDGIGSEVSEGQVLVLG 497
Query: 680 TTRRP--FDAELQSFCKVYQKIILVPRPDYASRYVLWKQIIERNGGVLTSA 728
T RP DA L+ + + K I + P+ R + ++++ R +LT A
Sbjct: 498 ATNRPHALDAALRRPGR-FDKEIEIGVPNAQDRLDILQKLLRRVPHLLTEA 547
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 58.9 bits (141), Expect = 2e-08
Identities = 62/312 (19%), Positives = 148/312 (47%), Gaps = 43/312 (13%)
Query: 190 QEYRAKQSKMLGKKVTDTWAAALRIQKVWRRFHQRKETEKLREEEMIFLGMNPPPLFNEV 249
+E + ++ ++LG++ R Q++ R++ RKE E +EEE L E
Sbjct: 1054 EELQQEEEQLLGEE-----RETRRRQELERQY--RKEEELQQEEEQ---------LLREE 1097
Query: 250 SATVIQAEKVDRLRNEVQIKHEEDY-----REALVTIKNDLKLIEGVDIKENLQDQIRHW 304
+ E+ + R E +++ EE+ RE + + + E ++++ ++Q+
Sbjct: 1098 PEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQE-EEQLLRE 1156
Query: 305 FIECRNLTGTFPDYPDVEEGGSAIIFSDKTIQQVIEDIIANQEEEEKNKKKKKKKEKQPK 364
E R Y + EE +QQ E ++ ++E+ + +++++ +E++
Sbjct: 1157 EPEKRRRQELERQYREEEE-----------LQQEEEQLLREEQEKRRQERERQYREEEEL 1205
Query: 365 KAKKQKKGTKEKNKEEDEKWKMSPSLFLPAMKEGCNAYKEIWMKKDESWNFSQDYDPELI 424
+ +K+K+ +++++ D KW+ P KE +++ K E+ F Q D +L
Sbjct: 1206 QRQKRKQRYRDEDQRSDLKWQWEPE------KENAVRDNKVYCKGRENEQFRQLEDSQLR 1259
Query: 425 KEEKRKELQSEIRIQVDELMRQELKNLKLAVDRERERPVKAGKKKDKKGKKGKKKEKKAK 484
+ +++LQ + Q + QE + + R+R P + +++++ K+ K++++K++
Sbjct: 1260 DRQSQQDLQHLLGEQQERDREQERRRWQ---QRDRHFPEEEQLEREEQ-KEAKRRDRKSQ 1315
Query: 485 KDKDLTADRTIE 496
++K L + E
Sbjct: 1316 EEKQLLREEREE 1327
Score = 47.8 bits (112), Expect = 4e-05
Identities = 31/164 (18%), Positives = 89/164 (54%), Gaps = 3/164 (1%)
Query: 336 QQVIEDIIANQEEEEKNKKKKKKKEKQPKKAKKQKKGTKEKNKEEDEKWKMSPSLFLPAM 395
QQ+ + +E+EE+ ++K ++E++ ++ K++++ ++ K E+E + +
Sbjct: 417 QQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQL 476
Query: 396 K-EGCNAYKEIWMKKDESWNFSQD--YDPELIKEEKRKELQSEIRIQVDELMRQELKNLK 452
K + +E W+K +E Q + +L +E++ + Q R + +E ++Q L++ +
Sbjct: 477 KRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQ 536
Query: 453 LAVDRERERPVKAGKKKDKKGKKGKKKEKKAKKDKDLTADRTIE 496
+ ER + K++++K + +++E++ K++++ D+ ++
Sbjct: 537 QLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLK 580
Score = 44.3 bits (103), Expect = 5e-04
Identities = 35/166 (21%), Positives = 85/166 (51%), Gaps = 12/166 (7%)
Query: 340 EDIIANQEEEEKNKKKKKKKEKQPKKAKKQKKGTKEKNKEEDEKWKMSPSLFLPAMKEGC 399
E + ++EE + + K+++EK+ ++ +++++ +E+ + D+ K +K
Sbjct: 535 EQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQ 594
Query: 400 NAYKEIWMKKDESWNFSQDYDPELIKEEKRKELQSEIRIQVDELMRQELKNLKLAVDRER 459
E +K++E E +++E+R+E Q R + +E RQ+L LK ER
Sbjct: 595 EERLEQRLKREE---------VERLEQEERRE-QRLKREEPEEERRQQL--LKSEEQEER 642
Query: 460 ERPVKAGKKKDKKGKKGKKKEKKAKKDKDLTADRTIESLYKELVEE 505
+ ++++++ ++ K++E++ + ++ L + E +EL EE
Sbjct: 643 RQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEE 688
Score = 43.9 bits (102), Expect = 6e-04
Identities = 70/337 (20%), Positives = 153/337 (45%), Gaps = 60/337 (17%)
Query: 169 QIAERARQGRLRALFMKQIYLQEYRAKQSKMLGKKVTDTWAAALRIQKVWRRFHQRKETE 228
Q E++ +GR R + L+E R +Q + ++ + +K RR QR+E
Sbjct: 772 QAEEKSERGRQR--LSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRR-RQRRE-- 826
Query: 229 KLREEEMIFLGMNPPPLFNEVSATVIQAEKVDRLRNEVQIKHEEDYREALVTIKNDLKLI 288
RE+E+ FL + E++ R Q++ EED ++ D +
Sbjct: 827 --REKELQFLE---------------EEEQLQRRERAQQLQEEED------GLQEDQERR 863
Query: 289 EGVDIKENLQDQIRHWFIE--CRNLTGTFPDYPDVEEGGSAIIFSDKTIQQVIEDIIANQ 346
+E +DQ W +E + T P ++E + QQ++++
Sbjct: 864 RS---QEQRRDQKWRWQLEEERKRRRHTLYAKPALQE-------QLRKEQQLLQEEEEEL 913
Query: 347 EEEEKNKKKKKKKEKQPKKAKKQKKGTKEKNKEEDEKWKMSPSLFLPAMKEGCNAYKEIW 406
+ EE+ K++++++E+Q ++ ++ ++ ++ +EE EK + +E
Sbjct: 914 QREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQE--------------RERQ 959
Query: 407 MKKDESWNFSQDYDPELIKE--EKRKELQSEIRIQVDELMRQELKNLKLAVDRERERPVK 464
+KD+ Q + +L+ E EKR+ + E + + +E ++QE + L L +RE+ R +
Sbjct: 960 YRKDKK---LQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQL-LREEREKRRRQE 1015
Query: 465 AGKKKDKKGKKGKKKEKKAKKDKDLTADRTIESLYKE 501
++ KK + +++E+ +++++ + E Y+E
Sbjct: 1016 WERQYRKKDELQQEEEQLLREEREKRRLQERERQYRE 1052
Score = 42.4 bits (98), Expect = 0.002
Identities = 31/166 (18%), Positives = 87/166 (52%), Gaps = 9/166 (5%)
Query: 348 EEEKNKKKKKKKEKQPKKAKKQKKGTKEKNKEEDEKWKMSPSLFLPAMKEGCNAYKEIWM 407
EEE+ +++++++E+Q ++ +++++ + K +EE+E+ + +E +E +
Sbjct: 492 EEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQ-EERREQLL 550
Query: 408 KKDESWNFSQDYDPELIKEEKRKELQSEIRIQVDELMRQELKNLKLAVDRERERPVKAGK 467
K++E Q+ +E++ K Q E R D+L+++E + + + RE+E ++
Sbjct: 551 KREEEKRLEQER-----REQRLKREQEERR---DQLLKREEERRQQRLKREQEERLEQRL 602
Query: 468 KKDKKGKKGKKKEKKAKKDKDLTADRTIESLYKELVEEGLLIQALK 513
K+++ + +++ ++ + ++ + + L K +E Q L+
Sbjct: 603 KREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLR 648
Score = 42.0 bits (97), Expect = 0.002
Identities = 28/142 (19%), Positives = 72/142 (50%), Gaps = 11/142 (7%)
Query: 346 QEEEEKNKKKKKKKEKQPKKAKKQKKGTKEKNKEEDEKWKMSPSLFLPAMKEGCNAYKEI 405
+ EE+K K++ +K ++ K+ ++++ K + +E D K++ L ++ +
Sbjct: 1300 EREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERD 1359
Query: 406 WMKKDESWNFSQDYDPELIKEEKRKELQSEIRIQVDELMRQELKNLKLAVDRERERPVKA 465
++E +E+ RK L+ E R++ E R+ LK + +ERE+ ++
Sbjct: 1360 RKFREEELRH---------QEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLR- 1409
Query: 466 GKKKDKKGKKGKKKEKKAKKDK 487
+ +D+K ++ +++ + ++D+
Sbjct: 1410 -QDRDRKFREEEQQLSRQERDR 1430
Score = 40.4 bits (93), Expect = 0.007
Identities = 77/366 (21%), Positives = 156/366 (42%), Gaps = 84/366 (22%)
Query: 157 KSIPFDEAVKLIQIAERARQGRLRALFMKQIYLQEYRAKQSKMLGKKVTDTWAAALRIQK 216
K + F E + +Q ERA+Q + +++ QE R Q + +K W L ++
Sbjct: 829 KELQFLEEEEQLQRRERAQQLQEEEDGLQED--QERRRSQEQRRDQK----WRWQLEEER 882
Query: 217 VWRR---FHQRKETEKLREEEMIFLGMNPPPLFNEVSATVIQAEKVDRLRNEVQIKHEED 273
RR + + E+LR+E+ L E + + E+ R R E E
Sbjct: 883 KRRRHTLYAKPALQEQLRKEQQ---------LLQEEEEELQREEREKRRRQE----QERQ 929
Query: 274 YREALVTIKNDLKLIEGVDIKENLQDQIRHWFIECRNLTGTFPDYPDVEEGGSAIIFSDK 333
YRE + + +L+ K Q++ R + DK
Sbjct: 930 YREEEQLQQEEEQLLREEREKRRRQERERQYR-------------------------KDK 964
Query: 334 TIQQVIEDIIANQEEEEKNKKKKKK-KEKQPKKAKKQKKGTKEKNKEEDEKWKMSPSLFL 392
+QQ E ++ + E+ + ++++KK +E++ + ++++ +E+ K ++W+
Sbjct: 965 KLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQ----- 1019
Query: 393 PAMKEGCNAYKEIWMKKDESWNFSQDYDPELIKEE--KRKELQSEIRIQVDELMRQELKN 450
+ KKDE Q + +L++EE KR+ + E + + +E ++QE +
Sbjct: 1020 -------------YRKKDEL----QQEEEQLLREEREKRRLQERERQYREEEELQQEEEQ 1062
Query: 451 LKLAVDRERERPVKAGKKKDKKGKKGKKKE--------KKAKKDKDLTADRTIESLYKEL 502
L L +RE R + ++ K+ + +++E K+ +++++ R E L +E
Sbjct: 1063 L-LGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQC-REEEELQQE- 1119
Query: 503 VEEGLL 508
EE LL
Sbjct: 1120 -EEQLL 1124
Score = 40.0 bits (92), Expect = 0.009
Identities = 26/159 (16%), Positives = 84/159 (52%), Gaps = 12/159 (7%)
Query: 340 EDIIANQEEEEKNKKKKKKKEKQPKKAKKQKKGTKEKNKEEDEKWKMSPSLFLPAMKEGC 399
+D + +EEE++ +K++ K+ +K ++++ + + +EE+E+ + E
Sbjct: 234 QDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLR---------KLERQ 284
Query: 400 NAYKEIWMKKDESWNFSQDYDPELIKEEKRKELQSEIRIQVDELMRQELK---NLKLAVD 456
+E ++ + ++ +EE+R+E Q E R Q + +QE + L+ +
Sbjct: 285 ELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQE 344
Query: 457 RERERPVKAGKKKDKKGKKGKKKEKKAKKDKDLTADRTI 495
RE+ ++ ++++++ ++ ++++++ ++++ L ++ +
Sbjct: 345 ERREQQLRREQEEERREQQLRREQEEERREQQLRREQQL 383
Score = 38.5 bits (88), Expect = 0.026
Identities = 58/354 (16%), Positives = 152/354 (42%), Gaps = 71/354 (20%)
Query: 154 YPVKSIPFDEAVKLIQIAERARQGRLRALFMKQIYLQEYRAKQSKMLGKKVTDTWAAALR 213
+ + P +E ++ ++ E R+GR KQ Q+ R +Q ++ ++ W
Sbjct: 199 HETEEFPDEEQLRRRELLELRRKGREE----KQ---QQRRERQDRVFQEEEEKEWRK--- 248
Query: 214 IQKVWRRFHQRKETEKLREEEMIFLGMNPPPLFNEVSATVIQAEKVDR--LRNEVQIKHE 271
R RKE EKL+EEE P E+ Q K++R LR E Q E
Sbjct: 249 -----RETVLRKEEEKLQEEE--------PQRQRELQEEEEQLRKLERQELRRERQ---E 292
Query: 272 EDYREALVTIKNDLKLIEGVDIKENLQDQIRHWFIECRNLTGTFPDYPDVEEGGSAIIFS 331
E+ ++ + + L+ + + +E +++
Sbjct: 293 EEQQQQRLRREQQLRRKQEEERREQQEERRE----------------------------- 323
Query: 332 DKTIQQVIEDIIANQEEEEKNKKKKKKKEKQPKKAKKQKKGTKEKNKEEDEKWKMSPSLF 391
QQ + + E++ +++++++E+Q ++ +++++ ++ +E++E+ +
Sbjct: 324 ----QQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRR 379
Query: 392 LPAMKEGCNAYKEIWMKKDESWNFSQDYDPELIKEEKRKELQSEIRIQVDELMRQELKNL 451
++ +E +++++ Q + ++L+ E +++ ++ +R+E +
Sbjct: 380 EQQLRREQQLRREQQLRREQQLRREQQL-------RREQQLRREQQLRREQQLRREQEEE 432
Query: 452 KLAVDRERERPVKAGKKKDKKGKKGKKKEKKAKKDKDLTADRTIESLYKELVEE 505
+ E+ER + K++ ++ + K+E++ ++ + +R + L ++ EE
Sbjct: 433 RHEQKHEQERREQRLKREQEERRDWLKREEETERHEQ---ERRKQQLKRDQEEE 483
Score = 38.5 bits (88), Expect = 0.026
Identities = 25/159 (15%), Positives = 84/159 (52%), Gaps = 19/159 (11%)
Query: 347 EEEEKNKKKKKKKEKQPKKAKKQKKGTKEKNKEEDEKWKMSPSLFLPAMKEGCNAYKEIW 406
EE++ ++++++K + ++ ++++G ++ +E D K++ +++
Sbjct: 1584 EEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFRED---------------EQLL 1628
Query: 407 MKKDESWNFSQDYDPELIKEE---KRKELQSEIRIQVDELMRQELKNLKLAVDRERERPV 463
+++E Q+ D + ++EE +R+E + ++R D R+E + L+ +++ R
Sbjct: 1629 QEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQE 1688
Query: 464 KAGK-KKDKKGKKGKKKEKKAKKDKDLTADRTIESLYKE 501
+ K +++++ + +++E+K +++ + +E ++E
Sbjct: 1689 RDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFRE 1727
Score = 38.1 bits (87), Expect = 0.033
Identities = 48/259 (18%), Positives = 115/259 (44%), Gaps = 33/259 (12%)
Query: 257 EKVDRLRNEVQIKHEEDYREALVTIKNDLKLIEGVDIKENLQDQIRHWFIECRNLTGTFP 316
E+ +RL ++ +HEE+ RE +L E +E ++ +I W + +
Sbjct: 663 EEEERLEQRLKREHEEERRE------QELAEEEQEQARERIKSRIPKWQWQLESEA---- 712
Query: 317 DYPDVEEGGSAIIFSDKTIQQVIEDIIANQEEEEKNKKKKKKKEKQPKKAKKQKKGTKEK 376
+ + ++S Q E QE+EEK ++++ + + Q ++ +++ +E+
Sbjct: 713 ------DARQSKVYSRPRKQ---EGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQ 763
Query: 377 NKEEDEKW----KMSPSLFLPAMKEGCNAYKEIWMKKDESWNFSQDYDPELIKEE----K 428
++ +W K + + +E ++ +E Q + PE ++E +
Sbjct: 764 RRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQ 823
Query: 429 RKELQSEIRI--QVDELMR----QELKNLKLAVDRERERPVKAGKKKDKKGKKGKKKEKK 482
R+E + E++ + ++L R Q+L+ + + ++ER +++D+K + ++E+K
Sbjct: 824 RREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERK 883
Query: 483 AKKDKDLTADRTIESLYKE 501
++ E L KE
Sbjct: 884 RRRHTLYAKPALQEQLRKE 902
Score = 37.7 bits (86), Expect = 0.044
Identities = 68/350 (19%), Positives = 146/350 (41%), Gaps = 70/350 (20%)
Query: 169 QIAERARQGRLRALFMKQIYLQEYRAKQSKMLGKKVTDTWAAALRIQKVWRRFHQRKETE 228
Q E Q RLR+ +Q +E ++ ++L ++ R Q++ R +R++
Sbjct: 522 QEEEERLQQRLRS---EQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQL 578
Query: 229 KLREEEMIFLGMNPPPLFNEVSATVIQAEKVDRL----RNEVQIKHEEDYREALVTIKND 284
REEE + E ++ E+V+RL R E ++K EE E
Sbjct: 579 LKREEERRQQRLKREQ--EERLEQRLKREEVERLEQEERREQRLKREEPEEE------RR 630
Query: 285 LKLIEGVDIKENLQDQIRHWFIECRNLTGTFPDYPDVEEGGSAIIFSDKTIQQVIEDIIA 344
+L++ + +E Q Q+R + Q+ E +
Sbjct: 631 QQLLKSEEQEERRQQQLR------------------------------REQQERREQRLK 660
Query: 345 NQEEEEKNKKKKKKKEKQPKK----AKKQKKGTKEKNKEEDEKWKMSPSLFLPAMKEGCN 400
+EEEE+ +++ K++ ++ ++ A+++++ +E+ K KW+ L A
Sbjct: 661 REEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQW--QLESEADARQSK 718
Query: 401 AYKEIWMKKDESWNFSQDYDPELIKEEKRKELQSEIRIQVDELMRQELKNLKLAVDRERE 460
Y +K E Q+ +EEKR+ +SE++ Q +E ++ + + E+
Sbjct: 719 VYSR--PRKQEGQRRRQE------QEEKRRRRESELQWQEEERAHRQQQ------EEEQR 764
Query: 461 RPVKAGKKKDKKGKKGKKK-----EKKAKKDKDLTADRTIESLYKELVEE 505
R + ++K ++G+++ + ++++ L A+ + + L EE
Sbjct: 765 RDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEE 814
Score = 37.4 bits (85), Expect = 0.057
Identities = 34/175 (19%), Positives = 92/175 (52%), Gaps = 12/175 (6%)
Query: 340 EDIIANQEEEEKNKKKKKKKEKQPKKAKKQKKGTKEKNKEEDEKWKMSPSLFLPAMKEGC 399
E ++ +EE++ +++++ +K + + ++++ ++ + D K++ L ++EG
Sbjct: 1625 EQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQL----LQEG- 1679
Query: 400 NAYKEIWMKKDESWNFSQDYDPELIKEEK-RKELQSEIRIQVDELMRQELKNLKLAVDRE 458
+E +++ E ++ + +L ++E+ RK LQ E +++ EL R+ + +L + E
Sbjct: 1680 ---EEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETE 1736
Query: 459 RE---RPVKAGKKKDKKGKKGKKKEKKAKKDKDLTADRTIESLYKELVEEGLLIQ 510
+E R + K +++ + +++E++ ++ + R E L +E E+ L Q
Sbjct: 1737 QEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQ 1791
Score = 37.0 bits (84), Expect = 0.074
Identities = 54/300 (18%), Positives = 141/300 (47%), Gaps = 24/300 (8%)
Query: 212 LRIQKVWRRFHQRKETEKLREEEMIFLGMNPPPLFNEVSATVIQAEKVDRLRNEVQIKHE 271
LR Q+ ++ Q ++ K REEE F E V + E+ + E Q +
Sbjct: 1399 LRCQEREQQLRQDRD-RKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQ 1457
Query: 272 EDYREALVTIKNDLKLIEGVDIKENLQDQIRHWFIECRNLTGTFPDYPDVEEGGSAIIFS 331
E +R+ + + L E + + + Q++ R + E + L D F
Sbjct: 1458 ERHRKFR---EEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRK----------FR 1504
Query: 332 DKTIQQVIEDIIANQEEEEKNKKKKKKKEKQPKKAKKQKKGTKEKNKEEDEKWKMSPSLF 391
++ ++ + +EE++ +++++++K Q ++ ++++ +++ ++ D K++ L
Sbjct: 1505 EQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLR 1564
Query: 392 LPAMKEGCNAY-KEIWMKKDESWNFSQDYDPELIKEE---KRKELQSEIRIQVDELMRQE 447
++ + ++ + +E Q+ + + +++E +R+E Q ++R + D R++
Sbjct: 1565 QEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFRED 1624
Query: 448 LKNLKLAVDRERERPVKAGKKKDKKGKKGKKKEKKAKKDKDLTADRTIESLYKE-LVEEG 506
+ L +ERE +++D+K + + + ++ ++++ L DR + +E L++EG
Sbjct: 1625 EQLL-----QEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEG 1679
Score = 35.8 bits (81), Expect = 0.17
Identities = 41/246 (16%), Positives = 107/246 (43%), Gaps = 16/246 (6%)
Query: 263 RNEVQIKHEEDYREALVTIKNDLKLIEGVDIKENLQDQIRHWFIECRNLTGTFPDYPDVE 322
R Q + ED + + DL+ + G + + + + R W R+ FP+ +E
Sbjct: 1245 RENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRH----FPEEEQLE 1300
Query: 323 EGGSAIIFSDKTIQQVIEDIIANQEEEEKNKKKKKKKEKQPKKAKKQKKGTKEKNKEEDE 382
Q + ++ + EE++ +++ +K ++ ++ ++++ + +E D
Sbjct: 1301 REEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDR 1360
Query: 383 KWKMSP-------SLFLPAMKEGCNAYKEIWMKKDESWNFSQDYDPELIKEEKRKELQSE 435
K++ FL + +E K+E Q+ + +L ++ RK + E
Sbjct: 1361 KFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEE 1420
Query: 436 IRIQVDELMRQELKNLKLAVDRERERPVKAGKKKDKKGKKGKKKEKKAKKDKDLTADRTI 495
++ E R+ + + +ERER K +++ + +++ +K ++++ L +R
Sbjct: 1421 QQLSRQERDRKFREEEQQVRRQERER-----KFLEEEQQLRQERHRKFREEEQLLQEREE 1475
Query: 496 ESLYKE 501
+ L+++
Sbjct: 1476 QQLHRQ 1481
Score = 35.8 bits (81), Expect = 0.17
Identities = 25/155 (16%), Positives = 80/155 (51%), Gaps = 10/155 (6%)
Query: 340 EDIIANQEEEEKNKKKKKKKEKQPKKAKKQKKGTKEKNKEEDEKWKMSPSL--------F 391
E + +EE++ ++++ +K ++ ++ +++++ + +++E D K++ L
Sbjct: 1753 EQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQL 1812
Query: 392 LPAMKEGCNAYKEIWMKKDESWNFSQDYDPELIKEEKRKELQSEIRIQVDELMRQELKNL 451
P ++G ++E ++ +E + + E++ Q + R + EL ++E +
Sbjct: 1813 RPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKR 1872
Query: 452 KLAVDRE-RERPVKAGKKKDKKGKK-GKKKEKKAK 484
+ +R+ RE ++ +K++++ ++ G+ K ++ K
Sbjct: 1873 RQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGK 1907
Score = 34.3 bits (77), Expect = 0.48
Identities = 65/336 (19%), Positives = 150/336 (44%), Gaps = 48/336 (14%)
Query: 172 ERARQGRLRALFMKQIYLQEYRAKQSKMLGKKVTDTWAAALRIQKVWRRFHQRKETEK-L 230
E R+ R L+ K LQE K+ ++L ++ + +Q+ R +R+E E+
Sbjct: 879 EEERKRRRHTLYAKPA-LQEQLRKEQQLLQEEEEE-------LQREEREKRRRQEQERQY 930
Query: 231 REEEMIFLGMNPPPLFNEVSATVIQAEKVDRLRNEVQIKHEEDYREALVTIKNDLKLIEG 290
REEE + + +++ E+ R R E E YR+ + + +L+
Sbjct: 931 REEEQL----------QQEEEQLLREEREKRRRQE----RERQYRKDKKLQQKEEQLLGE 976
Query: 291 VDIKENLQDQIRHWFIECRNLTGTFPDYPDVEEGGSAIIFSDKTIQQVIEDIIANQEE-- 348
K Q++ + + E + EE +K +Q E ++E
Sbjct: 977 EPEKRRRQEREKKYREE---------EELQQEEEQLLREEREKRRRQEWERQYRKKDELQ 1027
Query: 349 -EEKNKKKKKKKEKQPKKAKKQKKGTKEKNKEEDEKWKMSPSLFLPAMKEGCNAYKEIWM 407
EE+ ++++++++ ++ ++Q + +E +EE++ L + E
Sbjct: 1028 QEEEQLLREEREKRRLQERERQYREEEELQQEEEQ-------LLGEERETRRRQELERQY 1080
Query: 408 KKDESWNFSQDYDPELIKE--EKRKELQSEIRIQVDELMRQELKNLKLAVDRERERPVKA 465
+K+E Q + +L++E EKR+ + E + + +E ++QE + L L +RE+ R +
Sbjct: 1081 RKEEE---LQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQL-LREEREKRRRQEL 1136
Query: 466 GKKKDKKGKKGKKKEKKAKKDKDLTADRTIESLYKE 501
++ ++ + +++E+ +++ + + +E Y+E
Sbjct: 1137 ERQYREEEEVQQEEEQLLREEPEKRRRQELERQYRE 1172
>gi|195539395 proteasome 26S ATPase subunit 6 [Homo sapiens]
Length = 403
Score = 58.9 bits (141), Expect = 2e-08
Identities = 80/353 (22%), Positives = 160/353 (45%), Gaps = 52/353 (14%)
Query: 417 QDYDPELIKEEKRKELQSEIRIQVDELMRQ------ELKNLK---------LAVDRERER 461
QDY +L++ ++ E+R Q+ EL +Q +LK L+ L E +
Sbjct: 24 QDYRKKLLEHKEIDGRLKELREQLKELTKQYEKSENDLKALQSVGQIVGEVLKQLTEEKF 83
Query: 462 PVKAGK-KKDKKGKKGKKKEKKAKKDKDLTADRTIESLYKELVEEGLLIQALKVNLSDYI 520
VKA + G + + + K K + D T ++ + L E + L N+S
Sbjct: 84 IVKATNGPRYVVGCRRQLDKSKLKPGTRVALDMTTLTIMRYLPRE---VDPLVYNMSHED 140
Query: 521 G---EYSYLGTTLRQVSIEPMPSLLDVRQLITLYGIWPLGSAAVHEKAPLV--KSLLLAG 575
YS +G Q+ ++R++I L PL + + ++ ++ K LL G
Sbjct: 141 PGNVSYSEIGGLSEQIR--------ELREVIEL----PLTNPELFQRVGIIPPKGCLLYG 188
Query: 576 PSGVGKKMLVHAICTETGANLFNLSSSNIAGKYPGKNGLQMMLHAVFKVARQLQPSVVWI 635
P G GK +L A+ ++ N + SS+I KY G++ ++ +F AR QP ++++
Sbjct: 189 PPGTGKTLLARAVASQLDCNFLKVVSSSIVDKYIGESA--RLIREMFNYARDHQPCIIFM 246
Query: 636 EDTEKTFYKKVPNAEKMNEPKRLKKHLPQILKLLKPDD---RILIVGTTRRP--FDAELQ 690
++ + ++ +E + + +++ L ++L + D R+ ++ T RP D L
Sbjct: 247 DEIDAIGGRRF--SEGTSADREIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTLDPALL 304
Query: 691 SFCKVYQKIILVPRPDYASRYVLWKQIIERNGGVLT--SALNVSCLAKVTDGF 741
++ +K I + P+ +R I++ + G +T ++ + K++DGF
Sbjct: 305 RPGRLDRK-IHIDLPNEQARL----DILKIHAGPITKHGEIDYEAIVKLSDGF 352
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 57.8 bits (138), Expect = 4e-08
Identities = 41/160 (25%), Positives = 81/160 (50%), Gaps = 9/160 (5%)
Query: 346 QEEEEKNKKKKKKKEKQPKKAKKQKKGTKEKNKEEDEKWKMSPSLFLPAMKEGCNAYKEI 405
+ E + +K++++KE++ ++ KK+KKG ++K + E +K + KEG K
Sbjct: 62 ERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKE-----NKEGEEKEKRK 116
Query: 406 WMKKDESWNFSQDYDPELIKEEK----RKELQSEIRIQVDELMRQELKNLKLAVDRERER 461
+K E S++ KEE+ RKE + + + E R+E K + E+E
Sbjct: 117 KKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEE 176
Query: 462 PVKAGKKKDKKGKKGKKKEKKAKKDKDLTADRTIESLYKE 501
K ++K++K ++ +KE+K ++++ +R E KE
Sbjct: 177 ERKEKERKERKKRERNRKERKKERERKERRERKKERKKKE 216
Score = 55.5 bits (132), Expect = 2e-07
Identities = 48/159 (30%), Positives = 83/159 (52%), Gaps = 6/159 (3%)
Query: 346 QEEEEKNKKKKKKKEKQPKKAKKQKKGTKEKNKEEDEKWKMSPSLFLPAMKEGCNAYKEI 405
+E +K KK ++KKE++ +K ++++K KE ++E K K + KEG ++
Sbjct: 79 RERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTS-KEGKERERKE 137
Query: 406 WMKKDESWNFSQDYDPELIKEEKRKELQSEIRIQVDELMRQELKNLKLAVDRERERPVKA 465
K++E + + E KE +RKE + R QV E +E K + ++RER K
Sbjct: 138 ERKREERKERERKKE-EREKERERKERKKRERKQVGE-KEEERKEKERKERKKRERNRKE 195
Query: 466 GKK-KDKKGKKGKKKE--KKAKKDKDLTADRTIESLYKE 501
KK +++K ++ +KKE KK ++ K+ DR KE
Sbjct: 196 RKKERERKERRERKKERKKKEERKKERQKDRQTNWREKE 234
Score = 53.9 bits (128), Expect = 6e-07
Identities = 42/158 (26%), Positives = 81/158 (51%), Gaps = 32/158 (20%)
Query: 345 NQEEEEKNKKKKKKKEKQPKKAKKQKKGTKEKNKEEDEKWKMSPSLFLPAMKEGCNAYKE 404
N+E EEK K+KKK+K+++ + +K+ K+ +++ ++ +E+ KE
Sbjct: 106 NKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREER-------------------KE 146
Query: 405 IWMKKDESWNFSQDYDPELIKEEKRKELQSEIRIQVDELMRQELKNLKLAVDRERERPVK 464
KK+E KE +RKE + R QV E +E K + ++RER K
Sbjct: 147 RERKKEER-----------EKERERKERKKRERKQVGE-KEEERKEKERKERKKRERNRK 194
Query: 465 AGKK-KDKKGKKGKKKEKKAKKDKDLTADRTIESLYKE 501
KK +++K ++ +KKE+K K+++ + ++ ++E
Sbjct: 195 ERKKERERKERRERKKERKKKEERKKERQKDRQTNWRE 232
Score = 42.7 bits (99), Expect = 0.001
Identities = 39/149 (26%), Positives = 74/149 (49%), Gaps = 7/149 (4%)
Query: 347 EEEEKNKKKKKKKEKQPKKAKKQKKGTKEKNKEEDEKWKMSPSLFLPAMKEGCNAYKEIW 406
E E+ ++ + +KE + ++ ++KK +E+ K + E+ K K+G +E
Sbjct: 37 EIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERE 96
Query: 407 MKK--DESWNFSQDYDPELIKEEK----RKELQSEIRIQVDELMRQELKNL-KLAVDRER 459
KK E N + + K+EK R + + R + +E R+E K + +RE+
Sbjct: 97 RKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREK 156
Query: 460 ERPVKAGKKKDKKGKKGKKKEKKAKKDKD 488
ER K KK+++K K++E+K K+ K+
Sbjct: 157 ERERKERKKRERKQVGEKEEERKEKERKE 185
Score = 38.1 bits (87), Expect = 0.033
Identities = 22/81 (27%), Positives = 46/81 (56%), Gaps = 1/81 (1%)
Query: 425 KEEKRKELQSEIRIQVDELMRQELKNLKLAVDRERERPVKAGKKKDKKGKKGKKKEKKAK 484
++++R+E + R + E R+ K K +R++E + ++++K+ K+G++KEK+ K
Sbjct: 59 RKKERREREKRKREREKERKRERGKKEKKG-ERKKEERERKKRRREKENKEGEEKEKRKK 117
Query: 485 KDKDLTADRTIESLYKELVEE 505
K+K + E +E EE
Sbjct: 118 KEKKERGRTSKEGKERERKEE 138
Score = 32.3 bits (72), Expect = 1.8
Identities = 12/40 (30%), Positives = 27/40 (67%)
Query: 346 QEEEEKNKKKKKKKEKQPKKAKKQKKGTKEKNKEEDEKWK 385
+E E K ++++KK+ K+ ++ KK+++ ++ N E E+ K
Sbjct: 198 KERERKERRERKKERKKKEERKKERQKDRQTNWREKERGK 237
Score = 30.4 bits (67), Expect = 7.0
Identities = 11/38 (28%), Positives = 26/38 (68%)
Query: 346 QEEEEKNKKKKKKKEKQPKKAKKQKKGTKEKNKEEDEK 383
+E E+ K++KKK+E++ ++ K ++ +EK + + E+
Sbjct: 203 KERRERKKERKKKEERKKERQKDRQTNWREKERGKRER 240
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 55.8 bits (133), Expect = 2e-07
Identities = 39/150 (26%), Positives = 73/150 (48%), Gaps = 7/150 (4%)
Query: 346 QEEEEKNKKKKKKKEKQPKKAKKQKKGTKEKNKEEDEKWKMSPSLFLPAMKEGCNAYKEI 405
++ +E+ K++K+++EK+ +K KK+KK + K + E+ K + K
Sbjct: 77 RKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRK 136
Query: 406 WMKKDESWNFSQDYDPELIKEEKRKELQSEIRIQVDELMRQELKNLKLAVDRERERPVKA 465
+K + + +E KRK+ + E R + E R+E K +ERER +
Sbjct: 137 KRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERK-------KERERKERR 189
Query: 466 GKKKDKKGKKGKKKEKKAKKDKDLTADRTI 495
+KK++K ++ KKKE+K + D D +
Sbjct: 190 ERKKERKKERRKKKERKKDRKTDRQTDSQV 219
Score = 54.7 bits (130), Expect = 3e-07
Identities = 34/153 (22%), Positives = 80/153 (52%), Gaps = 16/153 (10%)
Query: 335 IQQVIEDIIANQEEEEKNKKKKKKKEKQPKKAKKQKKGTKEKNKEEDEKWKMSPSLFLPA 394
+Q V I+ + ++++KK+++E++ +K +++K+ +E+ K+E +K K
Sbjct: 17 LQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKK-------- 68
Query: 395 MKEGCNAYKEIWMKKDESWNFSQDYDPELIKEEKRKELQSEIRIQVDELMRQELKNLKLA 454
+E +++ + E ++E+RK + + + + + R+E K K
Sbjct: 69 --------RERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKER 120
Query: 455 VDRERERPVKAGKKKDKKGKKGKKKEKKAKKDK 487
+RERE + +K+ K+ KK ++KE+K +K++
Sbjct: 121 KERERENKQRRERKRKKRRKKKRRKERKREKER 153
Score = 51.2 bits (121), Expect = 4e-06
Identities = 45/159 (28%), Positives = 82/159 (51%), Gaps = 10/159 (6%)
Query: 348 EEEKNKKKK----KKKEKQPKKAKKQKKGTKEKNKEEDEKWKMSPSLFLPAMKEGCNAYK 403
++EK K+KK K++E++ K+ +KQ+K +EK + + +K K +E K
Sbjct: 60 KKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRER-KKKK 118
Query: 404 EIWMKKDESWNFSQDYDPELIKEEKRKELQSEIRIQVDELMRQELKNLKLAVDRER---E 460
E ++ E+ + + K+++RKE + E E R++ K + RER E
Sbjct: 119 ERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKE 178
Query: 461 RPVKAGKKKDKKGKKGKKKEKKAKKD--KDLTADRTIES 497
R + +K+ ++ KK +KKE++ KK+ KD DR +S
Sbjct: 179 RKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDS 217
Score = 49.7 bits (117), Expect = 1e-05
Identities = 41/159 (25%), Positives = 81/159 (50%), Gaps = 14/159 (8%)
Query: 346 QEEEEKNKKKKKKKEKQPKKAKKQKKGTKEKNKEEDEKWKMSPSLFLPAMKEGCNAYKEI 405
+E +K KKK+KK+E+ ++ +K+K+ K++ KE EK + + +E
Sbjct: 56 RERGKKEKKKRKKRERGKERERKRKEREKQR-KERREKERRKRKKEKKKRERKQRGRRER 114
Query: 406 WMKKDESWNFSQDYDPELIKEEKRKELQSEIRIQVDELMRQELKNLKLAVDRERERPVKA 465
KK+ ++ + + +E KRK+ + + R R+E K K RER+R +
Sbjct: 115 KKKKERK---ERERENKQRRERKRKKRRKKKR-------RKERKREKERGKRERKRKKRK 164
Query: 466 GKKKDKK---GKKGKKKEKKAKKDKDLTADRTIESLYKE 501
++++KK +K +KKE++ K+ ++ +R E K+
Sbjct: 165 KEEREKKRERNRKERKKERERKERRERKKERKKERRKKK 203
Score = 48.9 bits (115), Expect = 2e-05
Identities = 43/156 (27%), Positives = 80/156 (51%), Gaps = 11/156 (7%)
Query: 346 QEEEEKNKKKKKKKEKQPKKAKKQKKGTKEKNKEEDEKWKMSPSLFLPAMKEGCNAYKEI 405
+E+ ++ ++K++K+E+ K+ KK+KK +E+ KE + K K KE +
Sbjct: 43 REKRKREREKERKRERGKKEKKKRKK--RERGKERERKRKEREK----QRKERREKERRK 96
Query: 406 WMKKDESWNFSQDYDPELIKEEKRKELQSEIRIQVDELMRQELKNLKLAVDRERERPVKA 465
K+ + Q E K+++RKE + E + + + R+ K K +ER+R +
Sbjct: 97 RKKEKKKRERKQRGRRERKKKKERKERERENKQRRE---RKRKKRRKKKRRKERKREKER 153
Query: 466 GKKKDKKGKKGKKKEKKAKKDKDLTADRTIESLYKE 501
GK++ K+ K+ KKE++ KK + +R E KE
Sbjct: 154 GKRERKRKKR--KKEEREKKRERNRKERKKERERKE 187
Score = 33.5 bits (75), Expect = 0.82
Identities = 14/56 (25%), Positives = 34/56 (60%), Gaps = 1/56 (1%)
Query: 345 NQEEEEKNKKKKKKKEKQPKKAKKQKKGTKEKNKEEDEKWKMSPSLFLPAMKEGCN 400
N++E +K +++K+++E++ K+ KK+++ KE+ K+ + +F P + N
Sbjct: 175 NRKERKKERERKERRERK-KERKKERRKKKERKKDRKTDRQTDSQVFRPLRESAFN 229
Score = 32.7 bits (73), Expect = 1.4
Identities = 19/55 (34%), Positives = 32/55 (58%), Gaps = 3/55 (5%)
Query: 442 ELMRQELKNLKLAVDRERERPVKAGKKKDKKGKK---GKKKEKKAKKDKDLTADR 493
E ++ + K +RE+ER + GKK+ KK KK GK++E+K K+ + +R
Sbjct: 35 ERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKER 89
Score = 31.2 bits (69), Expect = 4.1
Identities = 14/44 (31%), Positives = 28/44 (63%)
Query: 445 RQELKNLKLAVDRERERPVKAGKKKDKKGKKGKKKEKKAKKDKD 488
++E + K +RE+ + + ++K ++GKK KKK KK ++ K+
Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKE 74
>gi|6005942 valosin-containing protein [Homo sapiens]
Length = 806
Score = 55.5 bits (132), Expect = 2e-07
Identities = 43/174 (24%), Positives = 83/174 (47%), Gaps = 13/174 (7%)
Query: 541 LLDVRQLITLYGIWPLGSAAVHEKAPLVKSLLLAGPSGVGKKMLVHAICTETGANLFNLS 600
L +++++ L P A+ K P + +LL GP G GK ++ A+ ETGA F ++
Sbjct: 213 LAQIKEMVELPLRHPALFKAIGVKPP--RGILLYGPPGTGKTLIARAVANETGAFFFLIN 270
Query: 601 SSNIAGKYPGKNGLQMMLHAVFKVARQLQPSVVWIEDTEKTFYKKVPNAEKMN--EPKRL 658
I K G++ + L F+ A + P++++I++ + P EK + +R+
Sbjct: 271 GPEIMSKLAGES--ESNLRKAFEEAEKNAPAIIFIDELDAI----APKREKTHGEVERRI 324
Query: 659 KKHLPQILKLLKPDDRILIVGTTRRP--FDAELQSFCKVYQKIILVPRPDYASR 710
L ++ LK ++++ T RP D L+ F + + + + + PD R
Sbjct: 325 VSQLLTLMDGLKQRAHVIVMAATNRPNSIDPALRRFGR-FDREVDIGIPDATGR 377
Score = 55.1 bits (131), Expect = 3e-07
Identities = 43/184 (23%), Positives = 85/184 (46%), Gaps = 8/184 (4%)
Query: 569 KSLLLAGPSGVGKKMLVHAICTETGANLFNLSSSNIAGKYPGKNGLQMMLHAVFKVARQL 628
K +L GP G GK +L AI E AN ++ + + G++ + + +F ARQ
Sbjct: 512 KGVLFYGPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGES--EANVREIFDKARQA 569
Query: 629 QPSVVWIEDTEKTFYKKVPN-AEKMNEPKRLKKHLPQILKLLKPDDRILIVGTTRRP--F 685
P V++ ++ + + N + R+ + + + + I+G T RP
Sbjct: 570 APCVLFFDELDSIAKARGGNIGDGGGAADRVINQILTEMDGMSTKKNVFIIGATNRPDII 629
Query: 686 DAELQSFCKVYQKIILVPRPDYASRYVLWKQIIERNGGVLTSALNVSCLAKVTDGFTQGH 745
D + ++ Q +I +P PD SR + K + ++ + +++ LAK+T+GF+
Sbjct: 630 DPAILRPGRLDQ-LIYIPLPDEKSRVAILKANLRKS--PVAKDVDLEFLAKMTNGFSGAD 686
Query: 746 IVEV 749
+ E+
Sbjct: 687 LTEI 690
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 55.1 bits (131), Expect = 3e-07
Identities = 82/393 (20%), Positives = 175/393 (44%), Gaps = 52/393 (13%)
Query: 129 EVIKGREKILAQILADSGIDTSDMKYPVKSIPFDEAVKLIQIAERARQGRLRALFMKQ-- 186
E+ K R+ + ++ ++ +D + K+ E ++L++ + Q ++ L K
Sbjct: 197 ELTKERDALSLELYRNT---ITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLER 253
Query: 187 ---IYLQEYRAKQSKMLGKKVTDTWA---AALRIQKVWRRFHQRKETEKLREEEMIF--- 237
+ Q+ ++ LGK++ A A + ++W R +Q++E + R+EE I
Sbjct: 254 AKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWE 313
Query: 238 --LGMNPPPLFNEVSATVIQAEKVDRLRNEVQIKHEEDYREALVTIKNDLKLIEGVDIKE 295
+ + + Q EK+ R + K E+ R+ + + + K+ ++
Sbjct: 314 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW 373
Query: 296 NLQDQIRH-----WFIE--CRNLTGTFPDYPDVEEGGSAIIFSDKTIQQVI----EDIIA 344
++++R W E R L + + E +K +Q E +
Sbjct: 374 EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW 433
Query: 345 NQEE-----EEKNKKKKKKKEKQPKKAKKQKK-GTKEKNKEEDEKWKMSPSLFLPAMKEG 398
QEE EEK ++++KK +Q +K +Q+K +EK +E++E W+ +E
Sbjct: 434 RQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWR---------QEEK 484
Query: 399 CNAYKEIWMKKDESWNFSQDYDPELIK----EEKRKELQSEIRIQVDELMRQELKNLKLA 454
+ +EIW +K++ + + K EEK +E + +IR Q +++ RQE K
Sbjct: 485 IHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEK----- 539
Query: 455 VDRERERPVKAGKKKDKKGKKGKKKEKKAKKDK 487
RE+E + +K ++ K ++++++ ++DK
Sbjct: 540 -IREQEEMWREEEKMHEQEKIWEEEKRQEQEDK 571
Score = 47.0 bits (110), Expect = 7e-05
Identities = 37/160 (23%), Positives = 90/160 (56%), Gaps = 27/160 (16%)
Query: 347 EEEEKNKKKKKKKEKQPKKAKKQKKGTKEKNKEEDEK-WKMSPSLFLPAMKEGCNAYKEI 405
E+EEK +K+++K +Q +K ++Q+ EK +E++EK W+ +E +E+
Sbjct: 500 EQEEKIRKQEEKVWRQEEKIREQE----EKIREQEEKMWRQ---------EEKIREQEEM 546
Query: 406 WMKKDESWNFSQDYDPELIKEEKRKELQSE--IRIQVDELMRQELKNLKLAVDRERERPV 463
W ++++ + ++ E +E++ K + E IR Q +++ RQE K ++ ++ +E+
Sbjct: 547 WREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEK-IREQEEKRQEQEE 605
Query: 464 KAGKKKDK----------KGKKGKKKEKKAKKDKDLTADR 493
K K+++K + +K +++E+K ++ +++T ++
Sbjct: 606 KMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQ 645
Score = 45.4 bits (106), Expect = 2e-04
Identities = 57/293 (19%), Positives = 130/293 (44%), Gaps = 36/293 (12%)
Query: 215 QKVWRRFHQRKETEKLREEE-----------------MIFLGMNPPPLFNEVSATVIQAE 257
+K+WR+ + E EK+REEE + + + Q E
Sbjct: 451 KKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEE 510
Query: 258 KVDRLRNEVQIKHEEDYREALVTIKNDLKLIEGVDI---KENLQDQIRHWFIECRNLTGT 314
KV R +++ + E+ + + + K+ E ++ +E + +Q + W E R
Sbjct: 511 KVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQED 570
Query: 315 --FPDYPDVEEGGSAIIFSDKTIQQVIEDIIANQEEEEKNKKKKKKKEKQPKKAKKQK-- 370
+ + E + ++ I++ E QE+EEK K+++K +Q +K ++Q+
Sbjct: 571 KMWRQEEKIREQEEKVWRQEEKIREQEEK---RQEQEEKMWKQEEKIREQEEKIQEQEEK 627
Query: 371 -KGTKEKNKEEDEKWKMSPSLFLPAMKEGCNAYKEIWMKKDESWNFSQDYDPELIKEEKR 429
+ +EK +E++E + ++ C +++ +++ W E I+E+++
Sbjct: 628 IREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWR-----QEEKIREQEK 682
Query: 430 KELQSEIRIQVDELMRQELKNLKLAVDRERERPVKAGKKKDKKGKKGKKKEKK 482
K + E +I+ E M QE + + + E+ + +K ++ +K +++E+K
Sbjct: 683 KIREQEEKIREQEEMMQEQEE---KMWEQEEKMCEQEEKMQEQEEKMRRQEEK 732
Score = 39.7 bits (91), Expect = 0.011
Identities = 27/164 (16%), Positives = 85/164 (51%), Gaps = 7/164 (4%)
Query: 332 DKTIQQVIEDIIANQEEEEKNKKKKKKKEKQPKKAKKQKKGTKEKNKEEDEKWKMSPSLF 391
++ IQ+ E I +E+ + ++K +++E+ + +++ + +E E++EK + +
Sbjct: 313 EEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMM 372
Query: 392 LPAMKEGCNAYKEIWMKKDESWNFSQD-YDPELIKEEKRKELQSEIRIQVDELMRQELK- 449
++ + +W K+++ + ++ E I+E++ K + E + ++ QE K
Sbjct: 373 WEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM 432
Query: 450 -----NLKLAVDRERERPVKAGKKKDKKGKKGKKKEKKAKKDKD 488
++ ++ RE+ K ++++K ++ K +E++ +++++
Sbjct: 433 WRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQE 476
Score = 38.1 bits (87), Expect = 0.033
Identities = 49/239 (20%), Positives = 113/239 (47%), Gaps = 34/239 (14%)
Query: 215 QKVWRRFHQRKETEKL-REEEMIFLGMNPPPLFNEVSATVIQAEKVDRLRNEVQIKHEED 273
+K+WR+ + +E E++ REEE M+ E Q +K+ R +++ + E+
Sbjct: 531 EKMWRQEEKIREQEEMWREEEK----MHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKV 586
Query: 274 YREALVTIKNDLKLIEGVDIKENLQDQIRHWFIECRNLTGTFPDYPDVEEGGSAIIFSDK 333
+R+ + + K E + +++IR ++E I ++
Sbjct: 587 WRQEEKIREQEEKRQEQEEKMWKQEEKIRE-------------QEEKIQEQEEKIREQEE 633
Query: 334 TIQQVIEDIIANQEEEEKNKKKKKKKEKQPKKAKKQKKGT---KEKNKEEDEKWKMSPSL 390
I++ E QE+EEK ++++K +Q +K ++Q++ +EK +E+++K
Sbjct: 634 KIREQEE---MTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKK------- 683
Query: 391 FLPAMKEGCNAYKEIWMKKDESWNFSQDYDPELIKEEKRKELQSEIRIQVDELMRQELK 449
+ +E +E+ +++E ++ E +EEK +E + ++R Q +++ QE++
Sbjct: 684 -IREQEEKIREQEEMMQEQEEKMWEQEEKMCE--QEEKMQEQEEKMRRQEEKMWEQEVR 739
Score = 32.0 bits (71), Expect = 2.4
Identities = 35/178 (19%), Positives = 81/178 (45%), Gaps = 23/178 (12%)
Query: 215 QKVWRRFHQRKETEKLREEEMIFLGMNPPPLFNEVSATVIQAEKVDRLRNEVQIKHEEDY 274
+KVWR+ + +E E+ R+E+ + + + Q EK+ +++ + E
Sbjct: 584 EKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQ 643
Query: 275 REALVTIKNDLKLIEGVDIKENLQDQIRHWFIECRNLTGTFPDYPDVEEGGSAIIFSDKT 334
+ + + K+ E +E +Q+Q + + EE I +K
Sbjct: 644 EQEEKMGEQEEKMCEQ---EEKMQEQEETMWRQ--------------EE---KIREQEKK 683
Query: 335 IQQVIEDIIANQEE--EEKNKKKKKKKEKQPKKAKKQKKGTKEKNKEEDEKWKMSPSL 390
I++ E+ I QEE +E+ +K +++EK ++ +K ++ ++ ++E++ W+ L
Sbjct: 684 IREQ-EEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRL 740
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 54.3 bits (129), Expect = 5e-07
Identities = 76/388 (19%), Positives = 179/388 (46%), Gaps = 43/388 (11%)
Query: 129 EVIKGREKILAQILADSGIDTSDMKYPVKSIPFDEAVKLIQIAERARQGRLRALFMKQ-- 186
E+ K R+ + ++ ++ +D + K+ E ++L++ + Q ++ L K
Sbjct: 258 ELTKERDALSLELYRNT---ITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLER 314
Query: 187 ---IYLQEYRAKQSKMLGKKVTDTWA---AALRIQKVWRRFHQRKETEKLREEEMI---- 236
+ Q+ ++ LGK++ A A + ++W R +Q++E + R+EE I
Sbjct: 315 AKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWE 374
Query: 237 -FLGMNPPPLFNEVSATVIQAEKVDRLRNEVQIKHEEDYREALVTIKNDLKLIEGVDIKE 295
+ + + Q EK+ R + K E+ R+ + + + K+ ++
Sbjct: 375 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW 434
Query: 296 NLQDQIRHWFIECRNLTGTFPDYPDVEEGGSAIIFSDKTIQQVI-----EDIIANQEEEE 350
+++IR E + + + + I +K +Q E+ I +E+EE
Sbjct: 435 EKEEKIRE-LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKI--REQEE 491
Query: 351 KNKKKKKKKEKQPKKAKKQKK-GTKEKNKEEDEKWKMSPSLFLPAMKEGCNAYKEIWMKK 409
K +++++K +Q +K +Q+K +EK +E++E W+ +E +EIW +K
Sbjct: 492 KIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWR---------QEEKIREQEEIWRQK 542
Query: 410 ----DESWNFSQDYDPELIKEEKRKELQSEIRIQVDELMRQELKNLKLAVDRERERPVKA 465
++ + + +EEK + + +IR Q +++ RQE K ++ ++ RE+ K
Sbjct: 543 EKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEK-IREQEEKIREQEEKI 601
Query: 466 GKK----KDKKGKKGKKKEKKAKKDKDL 489
++ ++++ K G+++EK ++++ +
Sbjct: 602 REQEEMTQEQEEKMGEQEEKMCEQEEKM 629
Score = 42.0 bits (97), Expect = 0.002
Identities = 47/249 (18%), Positives = 112/249 (44%), Gaps = 30/249 (12%)
Query: 215 QKVWRRFHQRKETEKLREEEMIFLG---MNPPPLFNEVSATVIQAEKVDRLRNEVQIKHE 271
+K+WR+ + E EK+REEE E Q EK+ +++ + E
Sbjct: 498 EKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEE 557
Query: 272 EDYREALVTIKNDLKLIEGVDIKENLQDQIRHWFIECRNLTGTFPDYPDVEEGGSAIIFS 331
+ +R+ + K+ E + +++IR + R + ++ + +
Sbjct: 558 KMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGE 617
Query: 332 DKTIQQVIEDIIANQEEEEKNKKKKKKKEKQPKKAKKQKKGTKEK----NKEEDEKWKMS 387
+ +++ E QE+EEK +++++K +Q KK ++Q++ +E+ ++E++ W+
Sbjct: 618 QE--EKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQE 675
Query: 388 PSLFLPAMKEGCNAYKEIWMKKDESWNFSQDYDPELIKEEKRKELQSEIRI-QVDELMRQ 446
+ +E M++ E E ++ ++ K + E+R+ Q +E M++
Sbjct: 676 EKM----------CEQEEKMQEQE----------EKMRRQEEKMWEQEVRLRQQEEKMQE 715
Query: 447 ELKNLKLAV 455
++L+ A+
Sbjct: 716 HQEHLEAAI 724
Score = 39.7 bits (91), Expect = 0.011
Identities = 56/273 (20%), Positives = 123/273 (45%), Gaps = 48/273 (17%)
Query: 215 QKVWRRFHQRKETEKLREEEMIFLGMNPPPLFNEVSATVI-QAEKVDRLRNEVQIKHEED 273
+K+ + +R+E EK+RE+E E A + Q EK+ +++ + E+
Sbjct: 451 EKIREQEEKRQEEEKIREQEKR----------QEQEAKMWRQEEKIREQEEKIREQEEKM 500
Query: 274 YREALVTIKNDLKLIEGVDIKENLQDQIRHWFIECRNLTGTFPDYPDVEEGGSAIIFSDK 333
+R+ + + E + +E Q+Q W E + I +
Sbjct: 501 WRQ-----EEKIHEQEKIREEEKRQEQEEMWRQEEK-------------------IREQE 536
Query: 334 TIQQVIEDIIANQEEEEKNKKKKKKKEKQPKKAKKQKKGTKEKNKEEDEK-WKMSPSLFL 392
I + E I E+EEK +K+++K +Q +K Q+ EK +E++EK W+ +
Sbjct: 537 EIWRQKEKI---HEQEEKIRKQEEKMWRQEEKMHDQE----EKIREQEEKVWRQEEKI-- 587
Query: 393 PAMKEGCNAYKEIWMKKDESWNFSQDYDPELIKEEKRKELQSEIRIQVDELMRQELKNLK 452
+E +E K E +Q+ + ++ ++E++ Q E + +E MR++ + ++
Sbjct: 588 ---REQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIR 644
Query: 453 LAVDRERERPVKAGKKKDKKGKKGKKKEKKAKK 485
+ RE+ K ++++ ++ +K ++ +K
Sbjct: 645 EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEK 677
>gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens]
Length = 495
Score = 53.5 bits (127), Expect = 8e-07
Identities = 81/337 (24%), Positives = 143/337 (42%), Gaps = 80/337 (23%)
Query: 223 QRKETEKLREEEMIFLGMNPPPLFNEVSATVIQAEKVDRLRNEVQIKHEEDYREALVTIK 282
QRK+ +L + E L M + +AE+ RL+ E+Q+K EE L +K
Sbjct: 52 QRKQFLRLLQNEQFELDMEE---------AIQKAEENKRLK-ELQLKQEEKLAMELAKLK 101
Query: 283 ND-LKLIEGVDIKENLQDQIRHWFIECRNLTGTFPDYPDVEEGGSAIIFSD--------- 332
++ LK E ++ Q+R IE R L +E + I D
Sbjct: 102 HESLK-------DEKMRQQVRENSIELRELEKKLKAAYMNKERAAQIAEKDAIKYEQMKR 154
Query: 333 -----KTIQQVIEDIIA--NQEEEEKNKKK--------KKKKEKQPKKAKKQKKGTKEKN 377
KT+ + + II N E+++NK K K+ +E++ KK + ++ KEK
Sbjct: 155 DAEIAKTMMEEHKRIIKEENAAEDKRNKAKAQYYLDLEKQLEEQEKKKQEAYEQLLKEKL 214
Query: 378 K---------EEDEKWKMSPSLFLPAMKEGCNAYKE---IWMKKD------------ESW 413
EED+ K + AM+ +++ +W KK E
Sbjct: 215 MIDEIVRKIYEEDQLEKQQKLEKMNAMRRYIEEFQKEQALWRKKKREEMEEENRKIIEFA 274
Query: 414 NFSQDYDPELI-----KEEKRKELQSEIRIQVDELMRQ--ELKNLKLAVDRERERPVKAG 466
N Q + + + EEKR +LQ+ + +++E++RQ +L+ ++ + +E + +
Sbjct: 275 NMQQQREEDRMAKVQENEEKRLQLQNALTQKLEEMLRQREDLEQVRQELYQEEQAEIYKS 334
Query: 467 KKKDKKGKKGKKKEKKAKKDKDLTADRTIESLYKELV 503
K K+ + EKK +K K++ D + KELV
Sbjct: 335 KLKE-------EAEKKLRKQKEMKQDFEEQMALKELV 364
Score = 41.2 bits (95), Expect = 0.004
Identities = 86/434 (19%), Positives = 174/434 (40%), Gaps = 78/434 (17%)
Query: 47 VKYVQIFRNLENVYDQFVHPQKRILIRKVLDGVMGRILELKNE-MVELELTEFHYFDDIL 105
V+ Q R L+N +QF + I+K + + L+LK E + +EL + + + L
Sbjct: 51 VQRKQFLRLLQN--EQFELDMEEA-IQKAEENKRLKELQLKQEEKLAMELAKLKH--ESL 105
Query: 106 QDLKLAPQQLDIPIPKYFLKEKLEVIKGREKILAQILADSGIDTSDMKYP--VKSIPFDE 163
+D K+ Q + I L++KL+ ++ AQI I MK + +E
Sbjct: 106 KDEKMRQQVRENSIELRELEKKLKAAYMNKERAAQIAEKDAIKYEQMKRDAEIAKTMMEE 165
Query: 164 AVKLIQIAERARQGRLRALFMKQIYLQEYRAKQSKMLGKKVTDTWAAALRIQKVWRRFHQ 223
++I+ A R +A + L++ +Q K + L I ++ R+ ++
Sbjct: 166 HKRIIKEENAAEDKRNKAKAQYYLDLEKQLEEQEKKKQEAYEQLLKEKLMIDEIVRKIYE 225
Query: 224 RKETEKLR---------------EEEMIFLGMNPPPLFNEVSATVIQAEKVDRLRNEVQI 268
+ EK + ++E E + +I+ + + R E ++
Sbjct: 226 EDQLEKQQKLEKMNAMRRYIEEFQKEQALWRKKKREEMEEENRKIIEFANMQQQREEDRM 285
Query: 269 KHEEDYREALVTIKNDL--KLIEGVDIKENLQDQIRHWFIECRNLTGTFPDYPDVEEGGS 326
++ E + ++N L KL E + +E+L+ Q+R ++ +
Sbjct: 286 AKVQENEEKRLQLQNALTQKLEEMLRQREDLE-QVRQ----------------ELYQEEQ 328
Query: 327 AIIFSDKTIQQVIEDIIANQEEEEKNKKKKKKKEKQPKKAKKQKKGTKEKNKEEDEKWKM 386
A I+ K +EE EK +K+K+ ++ ++ K+ + KEE+E +
Sbjct: 329 AEIYKSKL-----------KEEAEKKLRKQKEMKQDFEEQMALKELVLQAAKEEEENF-- 375
Query: 387 SPSLFLPAMKEGCNAYKEIWMKKDESWNFSQDYDPELIKEEKRKELQSEIRIQVDELMRQ 446
+K F++D EL+ +K++ Q E R V++L+
Sbjct: 376 ---------------------RKTMLAKFAEDDRIELMNAQKQRMKQLEHRRAVEKLI-- 412
Query: 447 ELKNLKLAVDRERE 460
E + + D++RE
Sbjct: 413 EERRQQFLADKQRE 426
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 53.1 bits (126), Expect = 1e-06
Identities = 80/420 (19%), Positives = 193/420 (45%), Gaps = 61/420 (14%)
Query: 150 SDMKYPVKSIPFDEAVKLIQIAERARQGRLRALFMK----QIYLQEYRAK-QSKMLGKKV 204
+D + K+ E ++L++ + Q ++ L K Q+ L + + + ++ LGK++
Sbjct: 212 TDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKEL 271
Query: 205 TDTWA---AALRIQKVWRRFHQRKETEKLREEEMIFLGMNPPPLFNEVSATVIQAEKVDR 261
A A + ++W +Q++E + R+EE I Q ++
Sbjct: 272 QSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKI------------------QEQEEKM 313
Query: 262 LRNEVQIKHEED--YREALVTIKNDLKLIEGVDIKENLQDQIRHWFIECRNLTGTFPDYP 319
E++I+ +E+ +R+ + + K+ E D +++IR + R
Sbjct: 314 CEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIRE------QEE 367
Query: 320 DVEEGGSAIIFSDKTIQQVIEDIIANQEEEEKNKKKKKKKEKQPKKAKKQKKGTKEKNKE 379
+ I D+ IQ+ E++ ++EE+ ++++K++EK ++ KK ++ ++ ++
Sbjct: 368 KMWRQEEKIREQDEKIQEQEEEMW--RQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQ 425
Query: 380 EDEKWKMSPSLFLPAMKEGCNAYKEIWMKKDESWNFSQDYDPELIKEEKRK--ELQSEIR 437
E+E W+ +E +E+ ++E + E ++EE+ K E + +I+
Sbjct: 426 EEEMWRQ---------EEKIRELEEMMQDQEEKLREVE----EKMQEEEEKMQEQEEKIQ 472
Query: 438 IQVDELMRQELKNL---KLAVDRER--ERPVKAGKKKDK---KGKKGKKKEKKAKKDKDL 489
Q +++ QE K KL E+ E+ K ++++K + +K +++E+K ++ ++
Sbjct: 473 RQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEK 532
Query: 490 TADRTIESLYKE--LVEEGLLIQALKVNLSDYIGEYSYLGTTLRQVSIEPMPSLLDVRQL 547
++ + +E + E+ + +Q L+ L + LG R+ + +P+L + Q+
Sbjct: 533 MREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQV 592
Score = 47.4 bits (111), Expect = 6e-05
Identities = 60/310 (19%), Positives = 141/310 (45%), Gaps = 30/310 (9%)
Query: 192 YRAKQSKMLGKKVTDTWAAALRIQKVWRRFH----QRKETEKLREEEMIFLGMNPPPLFN 247
++ +Q KM K T + + I+K W R Q++ L EE + F +
Sbjct: 135 FKKRQEKMNEKNYT--FRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYI 192
Query: 248 EVSATVIQAEKVDRLRNEVQIKHEEDYREALVTIKNDLKLIEGV--DIKENLQDQIRHWF 305
E A ++ RN + +E+ +E ++ L+L+E +I+ N++D ++
Sbjct: 193 EKLTKERDAPSLELYRNTIT---DEELKEKNAELQEKLRLVESEKSEIQLNVKD-LKRKL 248
Query: 306 IECRNLTGTFPDYPDVEEGGSAIIFSDKTIQQVIEDI----IANQEEEEKNKKKKKKKEK 361
+ L + + G + +Q +E+ + NQ++EEK ++++K ++
Sbjct: 249 ERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQE 308
Query: 362 QPKKAKKQKKGTKEKNKEEDEKWKMSPSLFLPAMK---EGCNAYKEIWMKKDESWNFSQD 418
Q +K +Q+ +E +E++ W+ + K + +++ +++ +
Sbjct: 309 QEEKMCEQELKIRE---QEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQ 365
Query: 419 YDPELIKEEKRKELQSEIRIQVDELMRQELKNLKLAVDRERERPVKAGKKKDKKGKKGKK 478
+ +EEK +E +I+ Q +E+ RQE ++ RE+ K +K ++ KK ++
Sbjct: 366 EEKMWRQEEKIREQDEKIQEQEEEMWRQE--------EKIREQEEKRQEKMWRQEKKMRE 417
Query: 479 KEKKAKKDKD 488
+++K ++ ++
Sbjct: 418 QDEKIREQEE 427
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 53.1 bits (126), Expect = 1e-06
Identities = 80/420 (19%), Positives = 193/420 (45%), Gaps = 61/420 (14%)
Query: 150 SDMKYPVKSIPFDEAVKLIQIAERARQGRLRALFMK----QIYLQEYRAK-QSKMLGKKV 204
+D + K+ E ++L++ + Q ++ L K Q+ L + + + ++ LGK++
Sbjct: 212 TDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKEL 271
Query: 205 TDTWA---AALRIQKVWRRFHQRKETEKLREEEMIFLGMNPPPLFNEVSATVIQAEKVDR 261
A A + ++W +Q++E + R+EE I Q ++
Sbjct: 272 QSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKI------------------QEQEEKM 313
Query: 262 LRNEVQIKHEED--YREALVTIKNDLKLIEGVDIKENLQDQIRHWFIECRNLTGTFPDYP 319
E++I+ +E+ +R+ + + K+ E D +++IR + R
Sbjct: 314 CEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIRE------QEE 367
Query: 320 DVEEGGSAIIFSDKTIQQVIEDIIANQEEEEKNKKKKKKKEKQPKKAKKQKKGTKEKNKE 379
+ I D+ IQ+ E++ ++EE+ ++++K++EK ++ KK ++ ++ ++
Sbjct: 368 KMWRQEEKIREQDEKIQEQEEEMW--RQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQ 425
Query: 380 EDEKWKMSPSLFLPAMKEGCNAYKEIWMKKDESWNFSQDYDPELIKEEKRK--ELQSEIR 437
E+E W+ +E +E+ ++E + E ++EE+ K E + +I+
Sbjct: 426 EEEMWRQ---------EEKIRELEEMMQDQEEKLREVE----EKMQEEEEKMQEQEEKIQ 472
Query: 438 IQVDELMRQELKNL---KLAVDRER--ERPVKAGKKKDK---KGKKGKKKEKKAKKDKDL 489
Q +++ QE K KL E+ E+ K ++++K + +K +++E+K ++ ++
Sbjct: 473 RQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEK 532
Query: 490 TADRTIESLYKE--LVEEGLLIQALKVNLSDYIGEYSYLGTTLRQVSIEPMPSLLDVRQL 547
++ + +E + E+ + +Q L+ L + LG R+ + +P+L + Q+
Sbjct: 533 MREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQV 592
Score = 46.6 bits (109), Expect = 9e-05
Identities = 60/310 (19%), Positives = 141/310 (45%), Gaps = 30/310 (9%)
Query: 192 YRAKQSKMLGKKVTDTWAAALRIQKVWRRFH----QRKETEKLREEEMIFLGMNPPPLFN 247
++ +Q KM K T + + I+K W R Q++ L EE + F +
Sbjct: 135 FKKRQEKMNEKNYT--FRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYI 192
Query: 248 EVSATVIQAEKVDRLRNEVQIKHEEDYREALVTIKNDLKLIEGV--DIKENLQDQIRHWF 305
E A ++ RN + +E+ +E ++ L+L+E +I+ N++D ++
Sbjct: 193 EKLTKERDALSLELYRNTIT---DEELKEKNAELQEKLRLVESEKSEIQLNVKD-LKRKL 248
Query: 306 IECRNLTGTFPDYPDVEEGGSAIIFSDKTIQQVIEDI----IANQEEEEKNKKKKKKKEK 361
+ L + + G + +Q +E+ + NQ++EEK ++++K ++
Sbjct: 249 ERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQE 308
Query: 362 QPKKAKKQKKGTKEKNKEEDEKWKMSPSLFLPAMK---EGCNAYKEIWMKKDESWNFSQD 418
Q +K +Q+ +E +E++ W+ + K + +++ +++ +
Sbjct: 309 QEEKMCEQELKIRE---QEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQ 365
Query: 419 YDPELIKEEKRKELQSEIRIQVDELMRQELKNLKLAVDRERERPVKAGKKKDKKGKKGKK 478
+ +EEK +E +I+ Q +E+ RQE ++ RE+ K +K ++ KK ++
Sbjct: 366 EEKMWRQEEKIREQDEKIQEQEEEMWRQE--------EKIREQEEKRQEKMWRQEKKMRE 417
Query: 479 KEKKAKKDKD 488
+++K ++ ++
Sbjct: 418 QDEKIREQEE 427
>gi|45643125 nuclear VCP-like isoform 2 [Homo sapiens]
Length = 750
Score = 53.1 bits (126), Expect = 1e-06
Identities = 71/293 (24%), Positives = 128/293 (43%), Gaps = 47/293 (16%)
Query: 474 KKGKKKEKKAKKDKD--LTADRTIES-LYKELVEEGLLIQALKVNLSDYIGEYSYLGTTL 530
+KGK K K +K+ K+ D IE+ L K+ GL Q V D G TL
Sbjct: 113 RKGKLKNKGSKRKKEDLQEVDGEIEAVLQKKAKARGLEFQISNVKFEDVGGN----DMTL 168
Query: 531 RQVSIEPMPSLLDVR--QLITLYGIWPLGSAAVHEKAPLVKSLLLAGPSGVGKKMLVHAI 588
++V L+ +R ++ G+ P + +LL GP G GK +L HAI
Sbjct: 169 KEVC----KMLIHMRHPEVYHHLGVVP------------PRGVLLHGPPGCGKTLLAHAI 212
Query: 589 CTETGANLFNLSSSNIAGKYPGKNGLQMMLHAVFKVARQLQPSVVWIEDTEKTFYKKVPN 648
E + +++ I G++ + L +F+ A P +++I++ + K+
Sbjct: 213 AGELDLPILKVAAPEIVSGVSGES--EQKLRELFEQAVSNAPCIIFIDEIDAITPKREVA 270
Query: 649 AEKMNEPKRLKKHLPQILKLLKPDD--------RILIVGTTRRP--FDAELQSFCKVYQK 698
++ M ++ + Q+L + DD R+L++G T RP D L+ + + +
Sbjct: 271 SKDME-----RRIVAQLLTCM--DDLNNVAATARVLVIGATNRPDSLDPALRRAGR-FDR 322
Query: 699 IILVPRPDYASRYVLWKQIIERNGGVLTSALNVSCLAKVTDGFTQGHIVEVVK 751
I + PD ASR + + + + L A + LA +T GF ++ + +
Sbjct: 323 EICLGIPDEASRERILQTLCRKLR--LPQAFDFCHLAHLTPGFVGADLMALCR 373
Score = 52.8 bits (125), Expect = 1e-06
Identities = 41/186 (22%), Positives = 87/186 (46%), Gaps = 14/186 (7%)
Query: 509 IQALKVNLSDYIGEYSYLGTTLRQVSIEPMPS--------LLDVRQLITLYGIWPLGSAA 560
+Q L + L+D+I S + + ++ +P+ L D+R+ +T+ + P+ +
Sbjct: 440 MQGLCIELNDFIVALSSVQPSAKREGFVTVPNVTWADIGALEDIREELTMAILAPVRNPD 499
Query: 561 VHEKAPLVK--SLLLAGPSGVGKKMLVHAICTETGANLFNLSSSNIAGKYPGKNGLQMML 618
+ LV +LLAGP G GK +L A+ E+G N ++ + Y G++ + +
Sbjct: 500 QFKALGLVTPAGVLLAGPPGCGKTLLAKAVANESGLNFISVKGPELLNMYVGES--ERAV 557
Query: 619 HAVFKVARQLQPSVVWIEDTEKTFYKKVPNAEKMNEPKRLKKHLPQILKLLKPDDRILIV 678
VF+ A+ P V++ ++ + ++ + + R+ L + L+ ++ I+
Sbjct: 558 RQVFQRAKNSAPCVIFFDEVDALCPRR--SDRETGASVRVVNQLLTEMDGLEARQQVFIM 615
Query: 679 GTTRRP 684
T RP
Sbjct: 616 AATNRP 621
>gi|45643123 nuclear VCP-like isoform 1 [Homo sapiens]
Length = 856
Score = 53.1 bits (126), Expect = 1e-06
Identities = 71/293 (24%), Positives = 128/293 (43%), Gaps = 47/293 (16%)
Query: 474 KKGKKKEKKAKKDKD--LTADRTIES-LYKELVEEGLLIQALKVNLSDYIGEYSYLGTTL 530
+KGK K K +K+ K+ D IE+ L K+ GL Q V D G TL
Sbjct: 219 RKGKLKNKGSKRKKEDLQEVDGEIEAVLQKKAKARGLEFQISNVKFEDVGGN----DMTL 274
Query: 531 RQVSIEPMPSLLDVR--QLITLYGIWPLGSAAVHEKAPLVKSLLLAGPSGVGKKMLVHAI 588
++V L+ +R ++ G+ P + +LL GP G GK +L HAI
Sbjct: 275 KEVC----KMLIHMRHPEVYHHLGVVP------------PRGVLLHGPPGCGKTLLAHAI 318
Query: 589 CTETGANLFNLSSSNIAGKYPGKNGLQMMLHAVFKVARQLQPSVVWIEDTEKTFYKKVPN 648
E + +++ I G++ + L +F+ A P +++I++ + K+
Sbjct: 319 AGELDLPILKVAAPEIVSGVSGES--EQKLRELFEQAVSNAPCIIFIDEIDAITPKREVA 376
Query: 649 AEKMNEPKRLKKHLPQILKLLKPDD--------RILIVGTTRRP--FDAELQSFCKVYQK 698
++ M ++ + Q+L + DD R+L++G T RP D L+ + + +
Sbjct: 377 SKDME-----RRIVAQLLTCM--DDLNNVAATARVLVIGATNRPDSLDPALRRAGR-FDR 428
Query: 699 IILVPRPDYASRYVLWKQIIERNGGVLTSALNVSCLAKVTDGFTQGHIVEVVK 751
I + PD ASR + + + + L A + LA +T GF ++ + +
Sbjct: 429 EICLGIPDEASRERILQTLCRKLR--LPQAFDFCHLAHLTPGFVGADLMALCR 479
Score = 52.8 bits (125), Expect = 1e-06
Identities = 41/186 (22%), Positives = 87/186 (46%), Gaps = 14/186 (7%)
Query: 509 IQALKVNLSDYIGEYSYLGTTLRQVSIEPMPS--------LLDVRQLITLYGIWPLGSAA 560
+Q L + L+D+I S + + ++ +P+ L D+R+ +T+ + P+ +
Sbjct: 546 MQGLCIELNDFIVALSSVQPSAKREGFVTVPNVTWADIGALEDIREELTMAILAPVRNPD 605
Query: 561 VHEKAPLVK--SLLLAGPSGVGKKMLVHAICTETGANLFNLSSSNIAGKYPGKNGLQMML 618
+ LV +LLAGP G GK +L A+ E+G N ++ + Y G++ + +
Sbjct: 606 QFKALGLVTPAGVLLAGPPGCGKTLLAKAVANESGLNFISVKGPELLNMYVGES--ERAV 663
Query: 619 HAVFKVARQLQPSVVWIEDTEKTFYKKVPNAEKMNEPKRLKKHLPQILKLLKPDDRILIV 678
VF+ A+ P V++ ++ + ++ + + R+ L + L+ ++ I+
Sbjct: 664 RQVFQRAKNSAPCVIFFDEVDALCPRR--SDRETGASVRVVNQLLTEMDGLEARQQVFIM 721
Query: 679 GTTRRP 684
T RP
Sbjct: 722 AATNRP 727
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 52.8 bits (125), Expect = 1e-06
Identities = 39/153 (25%), Positives = 70/153 (45%), Gaps = 38/153 (24%)
Query: 333 KTIQQVIEDIIANQEEEEKNKKKKKKKEKQPKKAKKQKKGTKEKNKEEDEKWKMSPSLFL 392
K ++ E +EEE++ K+K+K+KEK+ +K KK+K EK KE++E+ K
Sbjct: 8 KETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK------- 60
Query: 393 PAMKEGCNAYKEIWMKKDESWNFSQDYDPELIKEEKRKELQSEIRIQVDELMRQELKNLK 452
++ KK+E ++ + E KEE+ KE
Sbjct: 61 -------KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKE--------------------- 92
Query: 453 LAVDRERERPVKAGKKKDKKGKKGKKKEKKAKK 485
+ R + K ++K+++ +K KK+ +K KK
Sbjct: 93 ---EGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122
Score = 40.8 bits (94), Expect = 0.005
Identities = 26/81 (32%), Positives = 44/81 (54%)
Query: 425 KEEKRKELQSEIRIQVDELMRQELKNLKLAVDRERERPVKAGKKKDKKGKKGKKKEKKAK 484
K++K+K+ ++E + +E +E K K R+ +R K KKK K+ +K K+KE++ K
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 485 KDKDLTADRTIESLYKELVEE 505
K K + E +E EE
Sbjct: 61 KRKRKRKKKKEEEEREEEEEE 81
Score = 33.9 bits (76), Expect = 0.63
Identities = 14/33 (42%), Positives = 23/33 (69%)
Query: 346 QEEEEKNKKKKKKKEKQPKKAKKQKKGTKEKNK 378
+EE + KKKKK++ K+ ++ KK+K+ K K K
Sbjct: 91 KEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123
Score = 32.3 bits (72), Expect = 1.8
Identities = 12/35 (34%), Positives = 26/35 (74%)
Query: 346 QEEEEKNKKKKKKKEKQPKKAKKQKKGTKEKNKEE 380
+E+EE ++KKKKK ++ ++ +++KK + K K++
Sbjct: 89 EEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123
Score = 30.8 bits (68), Expect = 5.3
Identities = 11/40 (27%), Positives = 28/40 (70%)
Query: 346 QEEEEKNKKKKKKKEKQPKKAKKQKKGTKEKNKEEDEKWK 385
+E+EE+ K++ ++++K+ K+ +K+++ K+K + K K
Sbjct: 84 EEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 52.8 bits (125), Expect = 1e-06
Identities = 50/154 (32%), Positives = 76/154 (49%), Gaps = 12/154 (7%)
Query: 345 NQEEEEKNKKKKKKKEKQPKKAKKQKKGTKEKNKEE-DEKWKMSPSLFLPAMKEGCNAYK 403
+ ++E K+ KK KKK K+ K K KK + + E D K + S L A K
Sbjct: 339 DSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLK------KASK 392
Query: 404 EIWMKKD-ESWNFSQDYDPELIKEEKRKELQSEIRIQVDELMRQELKNLKLAVDRERERP 462
KKD + FS D + EL +E +K+ + + + + ++ +KN + + D + E
Sbjct: 393 NDDKKKDAKKITFSTDSESELESKESQKDEKKDKKDSKTD-NKKSVKNDEESTDADSEPK 451
Query: 463 --VKAGKKKDKKGKKGKKKEKKAKKDKDLTADRT 494
K GKK +KKGKK KK+ K KKD A+ T
Sbjct: 452 GDSKKGKKDEKKGKKDSKKDDK-KKDAKKNAEST 484
Score = 37.7 bits (86), Expect = 0.044
Identities = 38/164 (23%), Positives = 73/164 (44%), Gaps = 21/164 (12%)
Query: 346 QEEEEKNKKKKKKKEKQPKK-AKKQKKGTKEKNKEEDEKWKMSPSLFLPAMKEGCNAYKE 404
+++ +KN KK E + K AKK K K+ K++D+K + K+ + E
Sbjct: 285 KKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVK--------KDTESTDAE 336
Query: 405 IWMKKDESWNFSQDYDPELIKEEKRKELQSEIRIQVDEL-----MRQELKNLKLAVDRER 459
KDE + +D +L K++K+K+ + E R + +NLK A +
Sbjct: 337 SGDSKDERKDTKKD-KKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDD 395
Query: 460 ERP------VKAGKKKDKKGKKGKKKEKKAKKDKDLTADRTIES 497
++ + + + K+ +K EKK KKD +++++
Sbjct: 396 KKKDAKKITFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKN 439
Score = 36.6 bits (83), Expect = 0.097
Identities = 43/189 (22%), Positives = 65/189 (34%), Gaps = 36/189 (19%)
Query: 336 QQVIEDIIANQEEEEKNKKKKKKKEKQPKKAKKQKKGTKEKNKEEDEKWKMSPSLFLPAM 395
+Q++E+ Q E +K K + +Q KK+ K + E N E +S +
Sbjct: 145 KQIVEEKTKRQNEADKTPLKSSHENEQSKKS----KSSSETNPESQNSKTVSKNCSQKDK 200
Query: 396 KEGCNAYKEIWMKKDESWNFSQDYDPELIKEEKRKELQSEIRIQVDELM----------- 444
K+ N+ K N +D + E+ SE + VD LM
Sbjct: 201 KDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSENSLNVDFLMLVGQSDDESIN 260
Query: 445 ---------RQELKNLKLAVDRERERPVKAGKKKD------------KKGKKGKKKEKKA 483
+ KN L + ++ K KK K KK KK KK
Sbjct: 261 FDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKD 320
Query: 484 KKDKDLTAD 492
K KD+ D
Sbjct: 321 DKKKDVKKD 329
Score = 33.5 bits (75), Expect = 0.82
Identities = 36/159 (22%), Positives = 64/159 (40%), Gaps = 28/159 (17%)
Query: 345 NQEEEEKNKKKKKKKEKQP------------------KKAKKQKKGTKEKNKEEDEKWKM 386
+Q++E+K+KK K K+ KK KK +K K+ +K++D+K
Sbjct: 418 SQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDA 477
Query: 387 SPSLFLPAMKEGCNAYKEIWMKKDESWNFSQDYDPELIKEEKRKELQSEIRIQVDELMRQ 446
+ E ++ +KKD+ + + + IK++ RK+ +S + DE +
Sbjct: 478 KKNA------ESTEMESDLELKKDKKHSKEKKGSKKDIKKDARKDTES-TDAEFDESSKT 530
Query: 447 ELK---NLKLAVDRERERPVKAGKKKDKKGKKGKKKEKK 482
K +K + E K G KK G K
Sbjct: 531 GFKTSTKIKGSDTESEESLYKPGAKKKIDESDGTSANSK 569
>gi|21327685 YME1-like 1 isoform 1 [Homo sapiens]
Length = 773
Score = 52.8 bits (125), Expect = 1e-06
Identities = 49/228 (21%), Positives = 97/228 (42%), Gaps = 8/228 (3%)
Query: 567 LVKSLLLAGPSGVGKKMLVHAICTETGANLFNLSSSNIAGKYPGKNGLQMMLHAVFKVAR 626
L K +LL GP G GK +L A+ E + S S + G + + +F+ A+
Sbjct: 371 LPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASR--IRNLFREAK 428
Query: 627 QLQPSVVWIEDTEKTFYKKVPNAEKMNEPKRLKKHLPQILKLLKPDDRILIVGTTRRPFD 686
P V++I++ + K++ + + + + L + + KP++ ++I+G T P +
Sbjct: 429 ANAPCVIFIDELDSVGGKRIESPMHPYSRQTINQLLAE-MDGFKPNEGVIIIGATNFP-E 486
Query: 687 AELQSFCKV--YQKIILVPRPDYASRYVLWKQIIERNGGVLTSALNVSCLAKVTDGFTQG 744
A + + + + VPRPD R + K + N +++ +A+ T GF+
Sbjct: 487 ALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYL--NKIKFDQSVDPEIIARGTVGFSGA 544
Query: 745 HIVEVVKGVLTDQRIRRQIHKPLTAVEFITAITSMNPVYKEEEESFKN 792
+ +V + + + +EF M P + E KN
Sbjct: 545 ELENLVNQAALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEIDNKN 592
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.134 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,626,549
Number of Sequences: 37866
Number of extensions: 1449033
Number of successful extensions: 25908
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 346
Number of HSP's successfully gapped in prelim test: 625
Number of HSP's that attempted gapping in prelim test: 11888
Number of HSP's gapped (non-prelim): 7354
length of query: 822
length of database: 18,247,518
effective HSP length: 111
effective length of query: 711
effective length of database: 14,044,392
effective search space: 9985562712
effective search space used: 9985562712
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.