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Search of human proteins with 40254891
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40254891 hypothetical protein FLJ20674 [Homo sapiens]
(540 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40254891 hypothetical protein FLJ20674 [Homo sapiens] 1100 0.0
gi|169214048 PREDICTED: hypothetical protein [Homo sapiens] 87 5e-17
gi|89057602 PREDICTED: hypothetical protein [Homo sapiens] 87 5e-17
gi|37551995 PREDICTED: hypothetical protein [Homo sapiens] 87 5e-17
gi|169203189 PREDICTED: hypothetical protein LOC338667 [Homo sap... 86 1e-16
gi|169203683 PREDICTED: hypothetical protein LOC338667 [Homo sap... 86 1e-16
gi|169202109 PREDICTED: hypothetical protein LOC338667 [Homo sap... 86 1e-16
gi|75709184 contactin 3 [Homo sapiens] 79 8e-15
gi|118572606 hemicentin 1 [Homo sapiens] 79 1e-14
gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens] 74 4e-13
gi|48476182 roundabout, axon guidance receptor, homolog 3 [Homo ... 72 1e-12
gi|109150416 peroxidasin [Homo sapiens] 69 8e-12
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 69 1e-11
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 67 3e-11
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 67 3e-11
gi|7657359 contactin 5 isoform long [Homo sapiens] 67 4e-11
gi|28373129 contactin 5 isoform short [Homo sapiens] 67 4e-11
gi|33519481 neural cell adhesion molecule 2 precursor [Homo sapi... 66 9e-11
gi|110349719 titin isoform N2-A [Homo sapiens] 65 2e-10
gi|193083163 roundabout, axon guidance receptor, homolog 2 isofo... 65 2e-10
gi|61888896 roundabout, axon guidance receptor, homolog 2 isofor... 65 2e-10
gi|4827022 contactin 2 precursor [Homo sapiens] 63 8e-10
gi|94420689 neural cell adhesion molecule 1 isoform 1 [Homo sapi... 62 1e-09
gi|115529478 neural cell adhesion molecule 1 isoform 3 [Homo sap... 62 1e-09
gi|7657361 contactin 6 [Homo sapiens] 62 2e-09
gi|19743806 roundabout 1 isoform b [Homo sapiens] 61 2e-09
gi|4506569 roundabout 1 isoform a [Homo sapiens] 61 2e-09
gi|45594240 limbic system-associated membrane protein [Homo sapi... 60 5e-09
gi|148886752 immunoglobulin superfamily, member 9B [Homo sapiens] 59 9e-09
gi|115529482 neural cell adhesion molecule 1 isoform 2 [Homo sap... 59 1e-08
>gi|40254891 hypothetical protein FLJ20674 [Homo sapiens]
Length = 540
Score = 1100 bits (2845), Expect = 0.0
Identities = 540/540 (100%), Positives = 540/540 (100%)
Query: 1 MAAGGSAPEPRVLVCLGALLAGWVAVGLEAVVIGEVHENVTLHCGNISGLRGQVTWYRNN 60
MAAGGSAPEPRVLVCLGALLAGWVAVGLEAVVIGEVHENVTLHCGNISGLRGQVTWYRNN
Sbjct: 1 MAAGGSAPEPRVLVCLGALLAGWVAVGLEAVVIGEVHENVTLHCGNISGLRGQVTWYRNN 60
Query: 61 SEPVFLLSSNSSLRPAEPRFSLVDATSLHIESLSLGDEGIYTCQEILNVTQWFQVWLQVA 120
SEPVFLLSSNSSLRPAEPRFSLVDATSLHIESLSLGDEGIYTCQEILNVTQWFQVWLQVA
Sbjct: 61 SEPVFLLSSNSSLRPAEPRFSLVDATSLHIESLSLGDEGIYTCQEILNVTQWFQVWLQVA 120
Query: 121 SGPYQIEVHIVATGTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHN 180
SGPYQIEVHIVATGTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHN
Sbjct: 121 SGPYQIEVHIVATGTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHN 180
Query: 181 LTVNFFSLLLISPNLQGNYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSFM 240
LTVNFFSLLLISPNLQGNYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSFM
Sbjct: 181 LTVNFFSLLLISPNLQGNYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSFM 240
Query: 241 LQLTCRWDGGYPDPDFLWIEEPGGVIVGKSKLGVEMLSESQLSDGKKFKCVTSHIVGPES 300
LQLTCRWDGGYPDPDFLWIEEPGGVIVGKSKLGVEMLSESQLSDGKKFKCVTSHIVGPES
Sbjct: 241 LQLTCRWDGGYPDPDFLWIEEPGGVIVGKSKLGVEMLSESQLSDGKKFKCVTSHIVGPES 300
Query: 301 GASCMVQIRGPSLLSEPMKTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSR 360
GASCMVQIRGPSLLSEPMKTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSR
Sbjct: 301 GASCMVQIRGPSLLSEPMKTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSR 360
Query: 361 HLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEPLNIGGIVGTIVS 420
HLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEPLNIGGIVGTIVS
Sbjct: 361 HLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEPLNIGGIVGTIVS 420
Query: 421 LLLLGLAIISGLLLHYSPVFCWKVGNTSRGQNMDDVMVLVDSEEEEEEEEEEEEDAAVGE 480
LLLLGLAIISGLLLHYSPVFCWKVGNTSRGQNMDDVMVLVDSEEEEEEEEEEEEDAAVGE
Sbjct: 421 LLLLGLAIISGLLLHYSPVFCWKVGNTSRGQNMDDVMVLVDSEEEEEEEEEEEEDAAVGE 480
Query: 481 QEGAREREELPKEIPKQDHIHRVTALVNGNIEQMGNGFQDLQDDSSEEQSDIVQEEDRPV 540
QEGAREREELPKEIPKQDHIHRVTALVNGNIEQMGNGFQDLQDDSSEEQSDIVQEEDRPV
Sbjct: 481 QEGAREREELPKEIPKQDHIHRVTALVNGNIEQMGNGFQDLQDDSSEEQSDIVQEEDRPV 540
>gi|169214048 PREDICTED: hypothetical protein [Homo sapiens]
Length = 881
Score = 86.7 bits (213), Expect = 5e-17
Identities = 75/265 (28%), Positives = 106/265 (40%), Gaps = 16/265 (6%)
Query: 142 YAARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISPNLQGNYTC 201
+ GS V C ++SRPP + W ++ G L L + P G Y C
Sbjct: 417 FVTAGSNVTLRCAAASRPPADITWSLADPAEAAVPAGSRLL-----LPAVGPGHAGTYAC 471
Query: 202 LALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWIEE 261
LA N + R R+ L V PP APQC + G L+ C W GG P +
Sbjct: 472 LAANPRTGRRRRSLLNLTVADLPPGAPQCSVEGGPGDRSLRFRCSWPGGAPAASLQFQGL 531
Query: 262 PGGVIVG--KSKLGVEMLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGP-SLLSEPM 318
P G+ G S L + + +LS G C+ H+V +C V P +L P+
Sbjct: 532 PEGIRAGPVSSVLLAAVPAHPRLS-GVPITCLARHLVATR---TCTVTPEAPREVLLHPL 587
Query: 319 KTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCS 378
G + + SG PP++ W R + SR ++QDG+ L I N S
Sbjct: 588 VAETQLGEAEVALEASGCPPPSRASWARE--GRPLAPGGGSRLRLSQDGRK--LHIGNFS 643
Query: 379 QDLDEGYYICRADSPVGVREMEIWL 403
D D G Y +G +I L
Sbjct: 644 LDWDLGNYSVLCSGALGAGGDQITL 668
>gi|89057602 PREDICTED: hypothetical protein [Homo sapiens]
Length = 881
Score = 86.7 bits (213), Expect = 5e-17
Identities = 75/265 (28%), Positives = 106/265 (40%), Gaps = 16/265 (6%)
Query: 142 YAARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISPNLQGNYTC 201
+ GS V C ++SRPP + W ++ G L L + P G Y C
Sbjct: 417 FVTAGSNVTLRCAAASRPPADITWSLADPAEAAVPAGSRLL-----LPAVGPGHAGTYAC 471
Query: 202 LALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWIEE 261
LA N + R R+ L V PP APQC + G L+ C W GG P +
Sbjct: 472 LAANPRTGRRRRSLLNLTVADLPPGAPQCSVEGGPGDRSLRFRCSWPGGAPAASLQFQGL 531
Query: 262 PGGVIVG--KSKLGVEMLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGP-SLLSEPM 318
P G+ G S L + + +LS G C+ H+V +C V P +L P+
Sbjct: 532 PEGIRAGPVSSVLLAAVPAHPRLS-GVPITCLARHLVATR---TCTVTPEAPREVLLHPL 587
Query: 319 KTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCS 378
G + + SG PP++ W R + SR ++QDG+ L I N S
Sbjct: 588 VAETRLGEAEVALEASGCPPPSRASWARE--GRPLAPGGGSRLRLSQDGRK--LHIGNFS 643
Query: 379 QDLDEGYYICRADSPVGVREMEIWL 403
D D G Y +G +I L
Sbjct: 644 LDWDLGNYSVLCSGALGAGGDQITL 668
>gi|37551995 PREDICTED: hypothetical protein [Homo sapiens]
Length = 867
Score = 86.7 bits (213), Expect = 5e-17
Identities = 75/265 (28%), Positives = 106/265 (40%), Gaps = 16/265 (6%)
Query: 142 YAARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISPNLQGNYTC 201
+ GS V C ++SRPP + W ++ G L L + P G Y C
Sbjct: 417 FVTAGSNVTLRCAAASRPPADITWSLADPAEAAVPAGSRLL-----LPAVGPGHAGTYAC 471
Query: 202 LALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWIEE 261
LA N + R R+ L V PP APQC + G L+ C W GG P +
Sbjct: 472 LAANPRTGRRRRSLLNLTVADLPPGAPQCSVEGGPGDRSLRFRCSWPGGAPAASLQFQGL 531
Query: 262 PGGVIVG--KSKLGVEMLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGP-SLLSEPM 318
P G+ G S L + + +LS G C+ H+V +C V P +L P+
Sbjct: 532 PEGIRAGPVSSVLLAAVPAHPRLS-GVPITCLARHLVATR---TCTVTPEAPREVLLHPL 587
Query: 319 KTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCS 378
G + + SG PP++ W R + SR ++QDG+ L I N S
Sbjct: 588 VAETRLGEAEVALEASGCPPPSRASWARE--GRPLAPGGGSRLRLSQDGRK--LHIGNFS 643
Query: 379 QDLDEGYYICRADSPVGVREMEIWL 403
D D G Y +G +I L
Sbjct: 644 LDWDLGNYSVLCSGALGAGGDQITL 668
>gi|169203189 PREDICTED: hypothetical protein LOC338667 [Homo
sapiens]
Length = 859
Score = 85.5 bits (210), Expect = 1e-16
Identities = 51/189 (26%), Positives = 86/189 (45%), Gaps = 5/189 (2%)
Query: 219 LVYYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWIEEPGGVIVG-KSKLGVEML 277
++ + P P CW+ G + L+C W GG P W++E + G S + V +L
Sbjct: 464 VMLWEPLGRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSMAVHLL 523
Query: 278 SESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSL-LSEPMKTCFTGGNVTLTCQVSGA 336
+ G++F C +H++ C +Q+ P L ++EP + GG L C + G
Sbjct: 524 QAQEDLAGREFTCRGTHLLRTPD-PHCHLQLEAPQLDVAEPRVSVLEGGEAWLECSLRGG 582
Query: 337 YPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGV 396
PPA++LWL Q + + +S ++ +G L I++ G Y C A + VG
Sbjct: 583 TPPAQLLWLG--PQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGN 640
Query: 397 REMEIWLSV 405
+ L V
Sbjct: 641 SSQSVLLEV 649
Score = 74.3 bits (181), Expect = 3e-13
Identities = 75/297 (25%), Positives = 113/297 (38%), Gaps = 39/297 (13%)
Query: 120 ASGPYQIEVHIVATGTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGH 179
A GP + + + G G +A+ +V SC ++S PP W L ++
Sbjct: 291 ADGPDKPVITMEPLGLTEEG-FWASEREEVTLSCLAASNPPSHYVW----LRDHTQVH-- 343
Query: 180 NLTVNFFSLLLISPNLQGNYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSF 239
T + + G YTCLA N + T +L +YYPP P C +S +
Sbjct: 344 --TGPTYVIARAGRVHTGLYTCLARNSYLDTRTQTTVQLTIYYPPEGQPSCAVHPSSEA- 400
Query: 240 MLQLTCRWDGGYPDPDFLWIEEPGGVIVGKSKLGVEMLSESQLSDGKKFKCVTSH-IVGP 298
+ L C W GG P W E P G + +QL G F C H + P
Sbjct: 401 -VTLLCAWPGGLPPAQLQW-EGPQGPGPTAPSNVTWSHAAAQLPSGSVFTCTGQHPALAP 458
Query: 299 ESGASCMVQIRGPSLLSEPMKTCFTGGN-----VTLTCQVSGAYPPAKILWLRNLTQPEV 353
A C V + P L P TC++ + L+C+ G PPA + WL QP
Sbjct: 459 P--ALCTVMLWEP--LGRP--TCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQP-- 510
Query: 354 IIQPSSRHLITQDGQNSTLTIH--NCSQDLDEGYYICRADSPVGVREMEIWLSVKEP 408
G +S++ +H +DL + CR + + L ++ P
Sbjct: 511 -----------LGGSSSSMAVHLLQAQEDLAGREFTCRGTHLLRTPDPHCHLQLEAP 556
>gi|169203683 PREDICTED: hypothetical protein LOC338667 [Homo
sapiens]
Length = 859
Score = 85.5 bits (210), Expect = 1e-16
Identities = 51/189 (26%), Positives = 86/189 (45%), Gaps = 5/189 (2%)
Query: 219 LVYYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWIEEPGGVIVG-KSKLGVEML 277
++ + P P CW+ G + L+C W GG P W++E + G S + V +L
Sbjct: 464 VMLWEPLGRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSMAVHLL 523
Query: 278 SESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSL-LSEPMKTCFTGGNVTLTCQVSGA 336
+ G++F C +H++ C +Q+ P L ++EP + GG L C + G
Sbjct: 524 QAQEDLAGREFTCRGTHLLRTPD-PHCHLQLEAPQLDVAEPRVSVLEGGEAWLECSLRGG 582
Query: 337 YPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGV 396
PPA++LWL Q + + +S ++ +G L I++ G Y C A + VG
Sbjct: 583 TPPAQLLWLG--PQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGN 640
Query: 397 REMEIWLSV 405
+ L V
Sbjct: 641 SSQSVLLEV 649
Score = 72.4 bits (176), Expect = 1e-12
Identities = 74/297 (24%), Positives = 112/297 (37%), Gaps = 39/297 (13%)
Query: 120 ASGPYQIEVHIVATGTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGH 179
A GP + + + G G +A+ +V SC ++S PP W L ++
Sbjct: 291 ADGPDKPVITMEPLGLTEEG-FWASEREEVTLSCLAASNPPSHYVW----LRDHTQVH-- 343
Query: 180 NLTVNFFSLLLISPNLQGNYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSF 239
T + + G YTCLA N + T +L +YYPP P C + +
Sbjct: 344 --TGPTYVIARAGRVHTGLYTCLARNSYLDTRTQTTVQLTIYYPPEGQPSCAVHPSPEA- 400
Query: 240 MLQLTCRWDGGYPDPDFLWIEEPGGVIVGKSKLGVEMLSESQLSDGKKFKCVTSH-IVGP 298
+ L C W GG P W E P G + +QL G F C H + P
Sbjct: 401 -VTLLCAWPGGLPPAQLQW-EGPQGPGPTAPSNVTWSHAAAQLPSGSVFTCTGQHPALAP 458
Query: 299 ESGASCMVQIRGPSLLSEPMKTCFTGGN-----VTLTCQVSGAYPPAKILWLRNLTQPEV 353
A C V + P L P TC++ + L+C+ G PPA + WL QP
Sbjct: 459 P--ALCTVMLWEP--LGRP--TCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQP-- 510
Query: 354 IIQPSSRHLITQDGQNSTLTIH--NCSQDLDEGYYICRADSPVGVREMEIWLSVKEP 408
G +S++ +H +DL + CR + + L ++ P
Sbjct: 511 -----------LGGSSSSMAVHLLQAQEDLAGREFTCRGTHLLRTPDPHCHLQLEAP 556
>gi|169202109 PREDICTED: hypothetical protein LOC338667 [Homo
sapiens]
Length = 859
Score = 85.5 bits (210), Expect = 1e-16
Identities = 51/189 (26%), Positives = 86/189 (45%), Gaps = 5/189 (2%)
Query: 219 LVYYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWIEEPGGVIVG-KSKLGVEML 277
++ + P P CW+ G + L+C W GG P W++E + G S + V +L
Sbjct: 464 VMLWEPLGRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSMAVHLL 523
Query: 278 SESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSL-LSEPMKTCFTGGNVTLTCQVSGA 336
+ G++F C +H++ C +Q+ P L ++EP + GG L C + G
Sbjct: 524 QAQEDLAGREFTCRGTHLLRTPD-PHCHLQLEAPQLDVAEPRVSVLEGGEAWLECSLRGG 582
Query: 337 YPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGV 396
PPA++LWL Q + + +S ++ +G L I++ G Y C A + VG
Sbjct: 583 TPPAQLLWLG--PQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGN 640
Query: 397 REMEIWLSV 405
+ L V
Sbjct: 641 SSQSVLLEV 649
Score = 72.4 bits (176), Expect = 1e-12
Identities = 74/297 (24%), Positives = 112/297 (37%), Gaps = 39/297 (13%)
Query: 120 ASGPYQIEVHIVATGTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGH 179
A GP + + + G G +A+ +V SC ++S PP W L ++
Sbjct: 291 ADGPDKPVITMEPLGLTEEG-FWASEREEVTLSCLAASNPPSHYVW----LRDHTQVH-- 343
Query: 180 NLTVNFFSLLLISPNLQGNYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSF 239
T + + G YTCLA N + T +L +YYPP P C + +
Sbjct: 344 --TGPTYVIARAGRVHTGLYTCLARNSYLDTRTQTTVQLTIYYPPEGQPSCAVHPSPEA- 400
Query: 240 MLQLTCRWDGGYPDPDFLWIEEPGGVIVGKSKLGVEMLSESQLSDGKKFKCVTSH-IVGP 298
+ L C W GG P W E P G + +QL G F C H + P
Sbjct: 401 -VTLLCAWPGGLPPAQLQW-EGPQGPGPTAPSNVTWSHAAAQLPSGSVFTCTGQHPALAP 458
Query: 299 ESGASCMVQIRGPSLLSEPMKTCFTGGN-----VTLTCQVSGAYPPAKILWLRNLTQPEV 353
A C V + P L P TC++ + L+C+ G PPA + WL QP
Sbjct: 459 P--ALCTVMLWEP--LGRP--TCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQP-- 510
Query: 354 IIQPSSRHLITQDGQNSTLTIH--NCSQDLDEGYYICRADSPVGVREMEIWLSVKEP 408
G +S++ +H +DL + CR + + L ++ P
Sbjct: 511 -----------LGGSSSSMAVHLLQAQEDLAGREFTCRGTHLLRTPDPHCHLQLEAP 556
>gi|75709184 contactin 3 [Homo sapiens]
Length = 1028
Score = 79.3 bits (194), Expect = 8e-15
Identities = 92/357 (25%), Positives = 138/357 (38%), Gaps = 50/357 (14%)
Query: 79 RFSLVDATSLHIESLSLGDEGIYTC--------QEILNVTQWFQVWLQVASGPYQIEVHI 130
RF + L+I + D G YTC +L + G Y+ ++ +
Sbjct: 172 RFVSQETGHLYISKVEPSDVGNYTCVVTSMVTNARVLGSPTPLVLRSDGVMGEYEPKIEV 231
Query: 131 VATGTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLL 190
TLP AA+GS V C + P P + W S F + + FS +L
Sbjct: 232 QFPETLP-----AAKGSTVKLECFALGNPIPQINW----RRSDGLPFSSKIKLRKFSGVL 282
Query: 191 ISPNLQ----GNYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASG-SFMLQLTC 245
PN Q G+Y C+A N R + V L YY P W Q+ ++ +
Sbjct: 283 EIPNFQQEDAGSYECIAEN---SRGKNVARGRLTYYAKPH----WVQLIKDVEIAVEDSL 335
Query: 246 RWD---GGYPDPDFLWIEEPGGVIVGKSKLGVE----MLSESQLSDGKKFKCVTSHIVG- 297
W+ G P P + W++ G +V + + +E +S ++D F+C+ + G
Sbjct: 336 YWECRASGKPKPSYRWLKN-GAALVLEERTQIENGALTISNLSVTDSGMFQCIAENKHGL 394
Query: 298 PESGASCMVQIRGPSLLSEPMKTCF---TGGNVTLTCQVSGAYPPAKILWLRNLTQPEVI 354
S A V P PMK G V+L C+ A P A W + +V
Sbjct: 395 VYSSAELKVVASAPDFSKNPMKKLVQVQVGSLVSLDCK-PRASPRALSSWKKG----DVS 449
Query: 355 IQPSSRHLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEPLNI 411
+Q R + DG L I N ++ D G Y C A++ G L V EP I
Sbjct: 450 VQEHERISLLNDG---GLKIANVTK-ADAGTYTCMAENQFGKANGTTHLVVTEPTRI 502
Score = 30.8 bits (68), Expect = 3.3
Identities = 92/424 (21%), Positives = 143/424 (33%), Gaps = 68/424 (16%)
Query: 33 IGEVHENVTLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSLVDATSLHIES 92
+G + +TLHC W N S+ + E R+ L + I
Sbjct: 39 VGSEDKKITLHCEARGNPSPHYRWQLNGSDIDMSM---------EHRYKLNGGNLVVINP 89
Query: 93 LSLGDEGIYTC--QEILNVTQWFQVWLQVASGPYQIEVHIVATGTLPNGTLYAARGSQVD 150
D G Y C L + LQ A ++ T T+ G V
Sbjct: 90 NRNWDTGTYQCFATNSLGTIVSREAKLQFA--------YLENFKTKMRSTVSVREGQGVV 141
Query: 151 FSCNSSSRPPP-----VVEWWFQALNSSSESFGHNLTVNFFSLLLIS---PNLQGNYTCL 202
C PPP W F S E L IS P+ GNYTC+
Sbjct: 142 LLCG----PPPHSGELSYAWIFNEYPSFVEEDSRRFVSQETGHLYISKVEPSDVGNYTCV 197
Query: 203 ALNQLSKRHRKVTTELLV---------YYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPD 253
+ ++ + LV Y P A+ ++L C + G P
Sbjct: 198 VTSMVTNARVLGSPTPLVLRSDGVMGEYEPKIEVQFPETLPAAKGSTVKLEC-FALGNPI 256
Query: 254 PDFLWIEEPGGVIVGKSKL----GVEMLSESQLSDGKKFKCVTSHIVGPESGASCMVQIR 309
P W G K KL GV + Q D ++C+ + G +
Sbjct: 257 PQINWRRSDGLPFSSKIKLRKFSGVLEIPNFQQEDAGSYECIAENSRGKNVARGRLTYYA 316
Query: 310 GPSLLSEPMKTCFTGGNVTL--TCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDG 367
P + + +K +L C+ SG P WL+N ++++ ++
Sbjct: 317 KPHWV-QLIKDVEIAVEDSLYWECRASGK-PKPSYRWLKN--GAALVLEERTQI------ 366
Query: 368 QNSTLTIHNCSQDLDEGYYICRADSPVGV----REMEIWLSV----KEPLN--IGGIVGT 417
+N LTI N S D G + C A++ G+ E+++ S K P+ + VG+
Sbjct: 367 ENGALTISNLSV-TDSGMFQCIAENKHGLVYSSAELKVVASAPDFSKNPMKKLVQVQVGS 425
Query: 418 IVSL 421
+VSL
Sbjct: 426 LVSL 429
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 79.0 bits (193), Expect = 1e-14
Identities = 94/379 (24%), Positives = 148/379 (39%), Gaps = 40/379 (10%)
Query: 38 ENVTLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEP-RFSLVDATSLHIESLSLG 96
E L C IS + +TW RN+ + +R AEP R + SL ++S+
Sbjct: 535 ERAVLTCLIISAVDYNLTWQRNDRD----------VRLAEPARIRTLANLSLELKSVKFN 584
Query: 97 DEGIYTCQ-EILNVTQWFQVWLQVASGPYQIEVHIVATGTLPNGTLYAARGSQVDFSCNS 155
D G Y C + V+L V P +P + GS+V C++
Sbjct: 585 DAGEYHCMVSSEGGSSAASVFLTVQEPP--------KVTVMPKNQSFTG-GSEVSIMCSA 635
Query: 156 SSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLI---SPNLQGNYTCLALNQLSKRHR 212
+ P P + W +N H + L I +P G Y CLA N + +
Sbjct: 636 TGYPKPKIAW---TVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNS-AGTDK 691
Query: 213 KVTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWIE-----EPGGVIV 267
+ +T + P Q +A G + + C+ G P P W + P ++
Sbjct: 692 QNSTLRYIEAPKLMVVQSELLVALGDITV-MECK-TSGIPPPQVKWFKGDLELRPSTFLI 749
Query: 268 GKSKLGVEMLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSLLSEPMKTCF-TGGN 326
LG+ + E+Q D + CV + G +G + P + EP G N
Sbjct: 750 IDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSMEIGSN 809
Query: 327 VTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQDLDEGYY 386
VTL C V G YP I W R L + +P S I+Q + ++ + D+G Y
Sbjct: 810 VTLPCYVQG-YPEPTIKW-RRLDNMPIFSRPFSVSSISQLRTGALFILNLWAS--DKGTY 865
Query: 387 ICRADSPVGVREMEIWLSV 405
IC A++ G + E ++V
Sbjct: 866 ICEAENQFGKIQSETTVTV 884
Score = 70.5 bits (171), Expect = 4e-12
Identities = 97/398 (24%), Positives = 154/398 (38%), Gaps = 51/398 (12%)
Query: 32 VIGEVHENVTLHCGNISGLRGQVT--------WYRNNSEPVFLLSSNSSLRPAEPRFSLV 83
VIG EN+T+ N L +V+ W +N E L++N+ + P
Sbjct: 2966 VIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKN--EQPIKLNTNTLIVPG------- 3016
Query: 84 DATSLHIESLSLGDEGIYTCQEILNVTQWFQVWLQVASGPYQIEVHIVATGTLPNGTLYA 143
+L I + D G YTC I + + + P I+ H + ++ N
Sbjct: 3017 -GRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVN----V 3071
Query: 144 ARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISPNLQ--GNYTC 201
G+ V C S++ PPPV+ W+ +ES + + L + + G Y C
Sbjct: 3072 REGTSVSLECESNAVPPPVITWYKNG-RMITESTHVEILADGQMLHIKKAEVSDTGQYVC 3130
Query: 202 LALNQLSKRHRKVTTELLVYYPPP-SAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWIE 260
A+N + + L VY PP P+ + + S + LTC G P P W++
Sbjct: 3131 RAINVAGRDDKNF--HLNVYVPPSIEGPEREVIVETISNPVTLTCD-ATGIPPPTIAWLK 3187
Query: 261 E----------PGGVIVGKSKLGVEMLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRG 310
++ G SKL ++ SQ SD + C+ S++ G +
Sbjct: 3188 NHKRIENSDSLEVRILSGGSKL---QIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVP 3244
Query: 311 PSLLSEPMK---TCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDG 367
PS+ + + G NV L C +G P I WL++ +P I I
Sbjct: 3245 PSVAGAEIPSDVSVLLGENVELVCNANG-IPTPLIQWLKD-GKP---IASGETERIRVSA 3299
Query: 368 QNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSV 405
STL I+ D G Y C A +P G + L+V
Sbjct: 3300 NGSTLNIYGALTS-DTGKYTCVATNPAGEEDRIFNLNV 3336
Score = 67.0 bits (162), Expect = 4e-11
Identities = 94/364 (25%), Positives = 137/364 (37%), Gaps = 54/364 (14%)
Query: 70 NSSLRPAEPRFSLVDATSLHIESLSLGDEGIYTCQEILNVTQWFQVWLQVASGPYQIEVH 129
NS++ P ++ SLHIE + L D G YTC NV + + VH
Sbjct: 927 NSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTC-VASNVA-------GTNNKTTSVVVH 978
Query: 130 IVATGTLPNGTLYAARGSQVDFSCNSSSRPPPVVEW--WFQALNSSSESFGHNLTVNFFS 187
++ T L G V C +S P P V W + +++SS F S
Sbjct: 979 VLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGAD---GS 1035
Query: 188 LLLISPNLQ--GNYTCLALNQLSKRHRKVTTELLVYYPP----------PSAPQCWAQMA 235
L ++SP + G Y C A N RKV +L VY P P + +A
Sbjct: 1036 LYVVSPGGEESGEYVCTATNTAGYAKRKV--QLTVYVRPRVFGDQRGLSQDKPVEISVLA 1093
Query: 236 SGSFMLQLTCRWDGGYPDPDFLWIEEPGGVIVGKSK-----LGVEMLSESQLSDGKKFKC 290
L + P P W +E + + G ++E++ SD + C
Sbjct: 1094 GEEVTLPCEVK---SLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLC 1150
Query: 291 VTSHIVGPESGA-SCMVQI-----RGPSLLSEPMKTCFTGGNVTLTCQVSGAYPPAKILW 344
V ++I G + A V + RGP L + G V + C G P I W
Sbjct: 1151 VATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQV-----GQRVDIPCNAQGT-PLPVITW 1204
Query: 345 LRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLS 404
+ ++ H+ DG TL+I + D G Y C A + G E EI L
Sbjct: 1205 SKG---GSTMLVDGEHHVSNPDG---TLSIDQATPS-DAGIYTCVATNIAGTDETEITLH 1257
Query: 405 VKEP 408
V+EP
Sbjct: 1258 VQEP 1261
Score = 63.9 bits (154), Expect = 4e-10
Identities = 89/393 (22%), Positives = 150/393 (38%), Gaps = 57/393 (14%)
Query: 54 VTWYRNNSEPVFLLSSNSSLRPAEPRFSLVDATSLHIESLSLGDEGIYTCQEILNVTQWF 113
+TW +++ +PV N ++ + L I L D G YTC +
Sbjct: 1858 ITWLKDD-QPVNTAQGNLKIQSS--------GRVLQIAKTLLEDAGRYTCVATNAAGETQ 1908
Query: 114 Q-VWLQVASGPYQIEVHIVATGTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWWFQ-ALN 171
Q + L V P + G + N T+ + Q++ C ++ P PV+ W+ L
Sbjct: 1909 QHIQLHVHEPP-----SLEDAGKMLNETVLVSNPVQLE--CKAAGNPVPVITWYKDNRLL 1961
Query: 172 SSSESFGHNLTVNFFSLLLISPNLQGNYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCW 231
S S S + + G Y C+A+N + ++ V +
Sbjct: 1962 SGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMV 2021
Query: 232 AQMASGSFMLQLTCRWDGGYPDPDFLWIEEPGGVIVGKSKLGVEMLS--------ESQLS 283
A + + L+ R G P P W+++ G V G+++LS +Q+S
Sbjct: 2022 AVVVNNPVRLECEAR---GIPAPSLTWLKD--GSPVSSFSNGLQVLSGGRILALTSAQIS 2076
Query: 284 DGKKFKCVTSHIVGPESGASCMVQIRGPSLLSEPMK-TCFTGGNVTLTCQVSGAYPPAKI 342
D ++ CV + G + + P+++ E + V L CQ S A PP +
Sbjct: 2077 DTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQ-SDAIPPPTL 2135
Query: 343 LWLRN----LTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVRE 398
WL++ L +P + I + L +D Q D G Y C A + G E
Sbjct: 2136 TWLKDGHPLLKKPGLSISENRSVLKIEDAQVQ-----------DTGRYTCEATNVAGKTE 2184
Query: 399 MEIWLSVKEPLNIGG---------IVGTIVSLL 422
+++ P NIGG I G ++SLL
Sbjct: 2185 KNYNVNIWVPPNIGGSDELTQLTVIEGNLISLL 2217
Score = 63.9 bits (154), Expect = 4e-10
Identities = 99/427 (23%), Positives = 167/427 (39%), Gaps = 70/427 (16%)
Query: 29 EAVVIGEVHE--NVTLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSLVDAT 86
E++ + V E +V+L C + + +TWY+N +++ ++ + L D
Sbjct: 3064 ESLSVVNVREGTSVSLECESNAVPPPVITWYKNGR----MITESTHVE------ILADGQ 3113
Query: 87 SLHIESLSLGDEGIYTCQEILNVTQWFQVWLQVASGP---YQIEVHIVATGTLPNGTLYA 143
LHI+ + D G Y C+ I VA + + V++ + P +
Sbjct: 3114 MLHIKKAEVSDTGQYVCRAI-----------NVAGRDDKNFHLNVYVPPSIEGPEREVIV 3162
Query: 144 ARGSQ-VDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFS------LLLISPNLQ 196
S V +C+++ PPP + W N +L V S + +
Sbjct: 3163 ETISNPVTLTCDATGIPPPTIAW---LKNHKRIENSDSLEVRILSGGSKLQIARSQHSDS 3219
Query: 197 GNYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSFML-----QLTCRWDGGY 251
GNYTC+A N K + + V PPS A++ S +L +L C +G
Sbjct: 3220 GNYTCIASNMEGKAQKYYFLSIQV---PPSV--AGAEIPSDVSVLLGENVELVCNANG-I 3273
Query: 252 PDPDFLWIEEPGGVIVGKSKLGVEMLSESQL-------SDGKKFKCVTSHIVGPES---- 300
P P W+++ + G+++ + S L SD K+ CV ++ G E
Sbjct: 3274 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFN 3333
Query: 301 -GASCMVQIRGPSLLSEPMKTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSS 359
IRG +E + T ++ + C+ +G PP +I WL+N + P S
Sbjct: 3334 LNVYVTPTIRGNKDEAEKLMT-LVDTSINIECRATGT-PPPQINWLKN-----GLPLPLS 3386
Query: 360 RHL-ITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEPLNIGGIVGTI 418
H+ + GQ + S D Y C A + GV L V P N+ +GT
Sbjct: 3387 SHIRLLAAGQVIRIVRAQVS---DVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTE 3443
Query: 419 VSLLLLG 425
+L G
Sbjct: 3444 EITVLKG 3450
Score = 61.6 bits (148), Expect = 2e-09
Identities = 91/378 (24%), Positives = 151/378 (39%), Gaps = 66/378 (17%)
Query: 53 QVTWYRNNSEPVFLLSSNSSLRPAEPRFSLVDATS--LHIESLSLGDEGIYTCQEILNVT 110
QV W++ + E LRP+ F ++D L I+ D G YTC I
Sbjct: 732 QVKWFKGDLE----------LRPST--FLIIDPLLGLLKIQETQDLDAGDYTCVAINEAG 779
Query: 111 QWF-QVWLQVASGPYQIEVHIVATGTLPNGTLYAARGSQVDFSCNSSSRPPPVVEW---- 165
+ ++ L V S P I+ + + GS V C P P ++W
Sbjct: 780 RATGKITLDVGSPPVFIQEPADVSMEI---------GSNVTLPCYVQGYPEPTIKWRRLD 830
Query: 166 ----WFQALNSSSESFGHNLTVNFFSLLLISPNLQGNYTCLALNQLSKRHRKVTTELLVY 221
+ + + SS S L +L + + +G Y C A NQ K + T +
Sbjct: 831 NMPIFSRPFSVSSIS---QLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGL 887
Query: 222 YPP-----PSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWI-------EEPGGVIVGK 269
P PS A + G L L C G P P+ WI + P +
Sbjct: 888 VAPLIGISPSV----ANVIEGQ-QLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSD 942
Query: 270 SKLGVEMLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSLL-SEPMKTCFTGGNVT 328
L +E + QL DG ++ CV S++ G + + +V P++ + + + G VT
Sbjct: 943 GSLHIERV---QLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVT 999
Query: 329 LTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQDLDE-GYYI 387
L C+ SG P ++W + + E+I S++ DG +++ S +E G Y+
Sbjct: 1000 LPCKASG-NPKPSVIWSK---KGELISTSSAKFSAGADG-----SLYVVSPGGEESGEYV 1050
Query: 388 CRADSPVGVREMEIWLSV 405
C A + G + ++ L+V
Sbjct: 1051 CTATNTAGYAKRKVQLTV 1068
Score = 60.5 bits (145), Expect = 4e-09
Identities = 89/320 (27%), Positives = 130/320 (40%), Gaps = 46/320 (14%)
Query: 120 ASGPYQIEVHIVAT----GTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWW------FQA 169
A Y ++V+I T G+ P + RG + C PPP V W +A
Sbjct: 2278 AKKEYNLQVYIRPTITNSGSHPT-EIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKA 2336
Query: 170 LNSSSESFGHNLTVNFFSLLLISPNLQGNYTCLALNQLSKRHRKVTTELLVYYPPP---- 225
GH L L I + G Y C+A+N +K +L V+ PP
Sbjct: 2337 KGVEILDEGHIL-----QLKNIHVSDTGRYVCVAVNVAGMTDKKY--DLSVHAPPSIIGN 2389
Query: 226 -SAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWIEEPGGVIVGKS---KLGVEM--LSE 279
+P+ + + S + LTC G P P W ++ V + S G M L +
Sbjct: 2390 HRSPENISVVEKNS--VSLTCE-ASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQ 2446
Query: 280 SQLSDGKKFKCVTSHIVGPES---GASCMV--QIRGPSLLSEPMKTCFTGGNVTLTCQVS 334
+ + D ++ CV + G E G S +V I G + L E +K +VTLTC+V+
Sbjct: 2447 TTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTL-EDVKV-KEKQSVTLTCEVT 2504
Query: 335 GAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQDLDEGYYICRADSPV 394
G P +I W ++ QP +Q H I G+ L I N Q G Y C A SP
Sbjct: 2505 G-NPVPEITWHKD-GQP---LQEDEAHHIISGGR--FLQITNV-QVPHTGRYTCLASSPA 2556
Query: 395 GVREMEIWLSVKEPLNIGGI 414
G + L+V I G+
Sbjct: 2557 GHKSRSFSLNVFVSPTIAGV 2576
Score = 60.5 bits (145), Expect = 4e-09
Identities = 84/348 (24%), Positives = 130/348 (37%), Gaps = 56/348 (16%)
Query: 88 LHIESLSLGDEGIYTCQEILNVTQWFQVWLQVASGP-------YQIEVHIVAT--GTLPN 138
L I + + D G YTC +AS P Y + VH+ GT
Sbjct: 3584 LRISTAQVEDTGRYTC---------------LASSPAGDDDKEYLVRVHVPPNIAGTDEP 3628
Query: 139 GTLYAARGSQVDFSCNSSSRPPPVVEWWFQALNSSSE------SFGHNLTVNFFSLLLIS 192
+ R QV C S + PPPV+ W + S G L +N L
Sbjct: 3629 RDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRYLQINNADL---- 3684
Query: 193 PNLQGNYTCLALNQLSKRHRKVTTELLVYYPP--PSAPQCWAQMASGSFMLQLTCRWDGG 250
NYTC+A N K R+ L V PP PQ + + S +L+ G
Sbjct: 3685 -GDTANYTCVASNIAGKTTREFI--LTVNVPPNIKGGPQSLVILLNKSTVLECIAE---G 3738
Query: 251 YPDPDFLWIEEPGGVIVGKS------KLGVEMLSESQLSDGKKFKCVTSHIVGPESGASC 304
P P W + G V+ G + G + + ++D ++ C+ ++ G +
Sbjct: 3739 VPTPRITW-RKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRID 3797
Query: 305 MVQIRGPSLLSEPMK-TCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLI 363
+ PS+ P T TL C+ +G P I W +N V +S L+
Sbjct: 3798 LQVHVPPSIAPGPTNMTVIVNVQTTLACEATG-IPKPSINWRKNGHLLNVDQNQNSYRLL 3856
Query: 364 TQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEPLNI 411
+ + +L I + S D D Y C + G + + L+V+ P +I
Sbjct: 3857 S----SGSLVIISPSVD-DTATYECTVTNGAGDDKRTVDLTVQVPPSI 3899
Score = 60.5 bits (145), Expect = 4e-09
Identities = 91/391 (23%), Positives = 143/391 (36%), Gaps = 41/391 (10%)
Query: 36 VHENVTLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSLVDATSLHIESLSL 95
V+ TL C + + W +N LL+ + + + + L+ + SL I S S+
Sbjct: 3817 VNVQTTLACEATGIPKPSINWRKNGH----LLNVDQN----QNSYRLLSSGSLVIISPSV 3868
Query: 96 GDEGIYTCQEILNVTQWFQVWLQVASGPYQIEVHIVATGTLPNGTLYAARGSQVDFSCNS 155
D Y C VT + Q+ I T + + +C +
Sbjct: 3869 DDTATYEC----TVTNGAGDDKRTVDLTVQVPPSIADEPT----DFLVTKHAPAVITCTA 3920
Query: 156 SSRPPPVVEWWFQALNSSSESFGHN-LTVNFFSLLLISPNLQGNYTCLALNQLSKRHRKV 214
S P P + W + G+ L+ +L N G YTC+A N HR V
Sbjct: 3921 SGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHV 3980
Query: 215 TTELLVYYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWIEEPGGVIVGKS---- 270
T L V+ PP PQ + + L C G P P W +E G+ V S
Sbjct: 3981 T--LHVHEPPVIQPQPSELHVILNNPILLPCE-ATGTPSPFITWQKE--GINVNTSGRNH 4035
Query: 271 ---KLGVEMLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSLLSEPMKTCFTGGN- 326
G +S + D + CV + G G + ++ P ++S +K +
Sbjct: 4036 AVLPSGGLQISRAVREDAGTYMCVAQNPAGTALG-KIKLNVQVPPVISPHLKEYVIAVDK 4094
Query: 327 -VTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQDLDEGY 385
+TL+C+ G PP I W ++ I++ S R + G + Q D G+
Sbjct: 4095 PITLSCEADG-LPPPDITWHKD---GRAIVE-SIRQRVLSSGSLQIAFV----QPGDAGH 4145
Query: 386 YICRADSPVGVREMEIWLSVKEPLNIGGIVG 416
Y C A + G L+V P I G
Sbjct: 4146 YTCMAANVAGSSSTSTKLTVHVPPRIRSTEG 4176
Score = 59.7 bits (143), Expect = 7e-09
Identities = 76/322 (23%), Positives = 129/322 (40%), Gaps = 39/322 (12%)
Query: 124 YQIEVHIVATGTLPNG-TLYAARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLT 182
+ + VH+ + P L + + +C S PPP + W N N
Sbjct: 2956 FNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSW---LKNEQPIKLNTNTL 3012
Query: 183 V----NFFSLLLISPNLQGNYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMAS-- 236
+ ++ + G YTC+A+NQ + +K + L Y PPS ++ S
Sbjct: 3013 IVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFS---LTVYVPPSIKDHDSESLSVV 3069
Query: 237 ---GSFMLQLTCRWDGGYPDPDFLWIEEPGGVIVGKSKLGVEMLSESQL--------SDG 285
+ L C P P W + G ++ +S VE+L++ Q+ SD
Sbjct: 3070 NVREGTSVSLECE-SNAVPPPVITWYKN--GRMITEST-HVEILADGQMLHIKKAEVSDT 3125
Query: 286 KKFKCVTSHIVGPESGASCMVQIRGPSLLSEPMKTCFT---GGNVTLTCQVSGAYPPAKI 342
++ C ++ G + + + + P + P + VTLTC +G PP I
Sbjct: 3126 GQYVCRAINVAGRDD-KNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGI-PPPTI 3183
Query: 343 LWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIW 402
WL+N + I+ S + S L I SQ D G Y C A + G + +
Sbjct: 3184 AWLKNHKR----IENSDSLEVRILSGGSKLQIAR-SQHSDSGNYTCIASNMEGKAQKYYF 3238
Query: 403 LSVKEPLNIGGI-VGTIVSLLL 423
LS++ P ++ G + + VS+LL
Sbjct: 3239 LSIQVPPSVAGAEIPSDVSVLL 3260
Score = 58.9 bits (141), Expect = 1e-08
Identities = 81/341 (23%), Positives = 133/341 (39%), Gaps = 48/341 (14%)
Query: 54 VTWYRNNSEPVFLLSSNSSLRPAEPRFSLVDATSLHIESLSLGDEGIYTCQEILNVTQWF 113
+ W ++N LL++ AEP L+ +E++ L D G YTC + N
Sbjct: 4200 INWKKDN----VLLANLLGKYTAEPYGELI------LENVVLEDSGFYTC--VANNAAGE 4247
Query: 114 QVWLQVASGPYQIEVHIVATGTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWWFQALNSS 173
+ + VH++ T T G + +G Q+ SC ++ P P + W F ++
Sbjct: 4248 D------THTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTF----NN 4297
Query: 174 SESFGHNLTVNFFSLLLI---SPNLQGNYTCLALNQLSKRHRKVTTELLVYYPP---PSA 227
+ H +VN S L+I S G Y C A N + K + V PP
Sbjct: 4298 NIIPAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVG--FVKAIGFVYVKEPPVFKGDY 4355
Query: 228 PQCWAQMASGSFMLQLTCRWDGGYPDPDFLWIEEPGGVIVGKSKLGVEMLSESQLS---- 283
P W + G+ +L + D P P W + GV + S + L L+
Sbjct: 4356 PSNWIEPLGGNAILNCEVKGD---PTPTIQWNRK--GVDIEISH-RIRQLGNGSLAIYGT 4409
Query: 284 ---DGKKFKCVTSHIVGPESGASCMVQIRGPSLLSEPMKTCF-TGGNVTLTCQVSGAYPP 339
D + CV ++ G + + P + EP++T GG + L CQ +G P
Sbjct: 4410 VNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGE-PQ 4468
Query: 340 AKILWLR---NLTQPEVIIQPSSRHLITQDGQNSTLTIHNC 377
I W R +++ + + S+ L D Q + C
Sbjct: 4469 PTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFEC 4509
Score = 58.2 bits (139), Expect = 2e-08
Identities = 64/266 (24%), Positives = 107/266 (40%), Gaps = 19/266 (7%)
Query: 149 VDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISPNLQGNYTCLALNQLS 208
+ SC + PPP + W L+ + + P G+YTC+A N
Sbjct: 4096 ITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAG 4155
Query: 209 KRHRKVTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWIEEPGGV--I 266
+T+L V+ PP + + L C DG P P W ++ + +
Sbjct: 4156 SS--STSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADG-IPTPAINWKKDNVLLANL 4212
Query: 267 VGK---SKLGVEMLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSLLSEPMKTCFT 323
+GK G +L L D + CV ++ G ++ + P+ P
Sbjct: 4213 LGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLN 4272
Query: 324 GGN-VTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQDLD 382
G + L+C+ +G P K+ W N I P+ H + +G +S L I S++ D
Sbjct: 4273 KGEQLRLSCKATGI-PLPKLTWTFNNN-----IIPA--HFDSVNG-HSELVIERVSKE-D 4322
Query: 383 EGYYICRADSPVGVREMEIWLSVKEP 408
G Y+C A++ VG + ++ VKEP
Sbjct: 4323 SGTYVCTAENSVGFVKAIGFVYVKEP 4348
Score = 57.4 bits (137), Expect = 3e-08
Identities = 89/406 (21%), Positives = 165/406 (40%), Gaps = 63/406 (15%)
Query: 35 EVHENVTLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSLVDATSLHIESLS 94
+V+ +TL C + ++WY++ L S+ + A + +L I+
Sbjct: 2687 KVNNTLTLECEAYAIPSASLSWYKDGQP----LKSDDHVNIA------ANGHTLQIKEAQ 2736
Query: 95 LGDEGIYTC--QEILNVTQW-FQVWLQVASGPYQI-EV-HIVATGTLPNGTLY-AARGSQ 148
+ D G YTC I + F V +QV ++ E+ +++ TG NG +
Sbjct: 2737 ISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGR--NGEAKDVIINNP 2794
Query: 149 VDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISPNL----------QGN 198
+ C +++ PPP + W+ GH LT + L+L + G
Sbjct: 2795 ISLYCETNAAPPPTLTWY---------KDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGR 2845
Query: 199 YTCLALNQLSKRHRKVTTELLVYYPP------PSAPQCWAQMASGSFMLQLTCRWDGGYP 252
YTC+A+N+ + + +LV PP P+ + + S +++ G P
Sbjct: 2846 YTCVAVNEAGEDSLQYDVRVLV--PPIIKGANSDLPEEVTVLVNKSALIECL---SSGSP 2900
Query: 253 DPDFLWIEEPGGVIVGK-----SKLGVEMLSESQLSDGKKFKCVTSHIVGPESGASCMVQ 307
P W ++ ++ S + + +Q++D ++ CV + G +
Sbjct: 2901 APRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNV 2960
Query: 308 IRGPSLLSEPMK--TCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQ 365
PS++ + T ++LTC+VSG +PP + WL+N E I+ ++ LI
Sbjct: 2961 HVPPSVIGPKSENLTVVVNNFISLTCEVSG-FPPPDLSWLKN----EQPIKLNTNTLIVP 3015
Query: 366 DGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEPLNI 411
G+ + S D G Y C A + G + + L+V P +I
Sbjct: 3016 GGRTLQIIRAKVS---DGGEYTCIAINQAGESKKKFSLTVYVPPSI 3058
Score = 57.0 bits (136), Expect = 4e-08
Identities = 85/353 (24%), Positives = 137/353 (38%), Gaps = 37/353 (10%)
Query: 85 ATSLHIESLSLGDEGIYTCQEILNV-TQWFQVWLQVASGPYQIEVHIVATGTLPNGTLYA 143
+ +L I ++L DEG Y C + + T Q + V+ P I+V PN
Sbjct: 481 SVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQV--------PNNVTVT 532
Query: 144 ARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISP--NLQGNYTC 201
G + +C S + W + T+ SL L S N G Y C
Sbjct: 533 P-GERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHC 591
Query: 202 LALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWIEE 261
+ ++ V L V PP Q +G + + C G YP P W
Sbjct: 592 MVSSEGGSSAASVF--LTVQEPPKVTVMPKNQSFTGGSEVSIMCSATG-YPKPKIAWTVN 648
Query: 262 PGGVIVGKSKL-----GVEMLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSLLSE 316
IVG + G + + D + C+ S+ G + S + I P L+
Sbjct: 649 DM-FIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVV 707
Query: 317 PMKTCFTGGNVT-LTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIH 375
+ G++T + C+ SG PP ++ W + ++ ++PS+ +I D L I
Sbjct: 708 QSELLVALGDITVMECKTSGI-PPPQVKWFKG----DLELRPSTFLII--DPLLGLLKIQ 760
Query: 376 NCSQDLDEGYYICRADSPVGVREMEIWLSV-------KEPLNIGGIVGTIVSL 421
+QDLD G Y C A + G +I L V +EP ++ +G+ V+L
Sbjct: 761 E-TQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSMEIGSNVTL 812
Score = 56.6 bits (135), Expect = 6e-08
Identities = 91/384 (23%), Positives = 144/384 (37%), Gaps = 47/384 (12%)
Query: 36 VHENVTLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSLVDATSLHIESLSL 95
V + +TL C +TW+++ V + R ++ + SL I +
Sbjct: 4092 VDKPITLSCEADGLPPPDITWHKDGRAIVESI-----------RQRVLSSGSLQIAFVQP 4140
Query: 96 GDEGIYTCQEILNVTQWFQVWLQVASGPYQIEVHIVATGTLPNGTLYAARGSQVDFSCNS 155
GD G YTC NV +S ++ VH+ G SQ C +
Sbjct: 4141 GDAGHYTCMAA-NVAG-------SSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVA 4192
Query: 156 SSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISPNLQ--GNYTCLALNQLSKRHRK 213
P P + W + ++ G + L+L + L+ G YTC+A N +
Sbjct: 4193 DGIPTPAINWKKDNVLLAN-LLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTH- 4250
Query: 214 VTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLW------IEEPGGVIV 267
T L V+ P + L+L+C+ G P P W I +
Sbjct: 4251 -TVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATG-IPLPKLTWTFNNNIIPAHFDSVN 4308
Query: 268 GKSKLGVEMLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSLLSEPMKTCFT---G 324
G S+L +E +S+ D + C + VG V ++ P + + + G
Sbjct: 4309 GHSELVIERVSKE---DSGTYVCTAENSVGFVKAIG-FVYVKEPPVFKGDYPSNWIEPLG 4364
Query: 325 GNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQDLDEG 384
GN L C+V G P I W R E+ H I Q G N +L I+ + D G
Sbjct: 4365 GNAILNCEVKGD-PTPTIQWNRKGVDIEI------SHRIRQLG-NGSLAIYGTVNE-DAG 4415
Query: 385 YYICRADSPVGVREMEIWLSVKEP 408
Y C A + GV E + L+++ P
Sbjct: 4416 DYTCVATNEAGVVERSMSLTLQSP 4439
Score = 55.5 bits (132), Expect = 1e-07
Identities = 83/374 (22%), Positives = 143/374 (38%), Gaps = 56/374 (14%)
Query: 53 QVTWYRNNSEPVFLLSSNSSLRPAEPRFSLVDATSLHIESLSLGDEGIYTCQ-------E 105
++TW ++ + +L+ N + R+S+++ LHI+S + D G Y C +
Sbjct: 3743 RITWRKDGA----VLAGNHA------RYSILENGFLHIQSAHVTDTGRYLCMATNAAGTD 3792
Query: 106 ILNVTQWFQVWLQVASGPYQIEVHIVATGTLPNGTLYAARGSQVDFSCNSSSRPPPVVEW 165
+ V +A GP + V + TL +C ++ P P + W
Sbjct: 3793 RRRIDLQVHVPPSIAPGPTNMTVIVNVQTTL---------------ACEATGIPKPSINW 3837
Query: 166 WFQA--LNSSSESFGHNLTVNFFSLLLISPNLQ--GNYTCLALNQLSKRHRKVTTELLVY 221
LN + L ++ SL++ISP++ Y C N R T +L V
Sbjct: 3838 RKNGHLLNVDQNQNSYRL-LSSGSLVIISPSVDDTATYECTVTNGAGDDKR--TVDLTVQ 3894
Query: 222 YPPPSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWIEE-----PGGVIVGKSKLGVEM 276
PP A + + + +TC G P P W + P G G
Sbjct: 3895 VPPSIADEPTDFLVTKHAPAVITCT-ASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIE 3953
Query: 277 LSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSLLSEPMKTCFTGGN-VTLTCQVSG 335
+ +QL+ ++ CV + G + P + +P + N + L C+ +G
Sbjct: 3954 ILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATG 4013
Query: 336 AYPPAKILWLRNLTQPEVIIQPSSR-HLITQDGQNSTLTIHNCSQDLDEGYYICRADSPV 394
P I W + + + S R H + G L I ++ D G Y+C A +P
Sbjct: 4014 T-PSPFITWQKE----GINVNTSGRNHAVLPSG---GLQISRAVRE-DAGTYMCVAQNPA 4064
Query: 395 GVREMEIWLSVKEP 408
G +I L+V+ P
Sbjct: 4065 GTALGKIKLNVQVP 4078
Score = 51.6 bits (122), Expect = 2e-06
Identities = 90/398 (22%), Positives = 152/398 (38%), Gaps = 57/398 (14%)
Query: 38 ENVTLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSLVDATSLHIESLSLGD 97
ENV L C N +G+ + + + +P+ +S R S + ++L+I D
Sbjct: 3262 ENVELVC-NANGIPTPLIQWLKDGKPI------ASGETERIRVS-ANGSTLNIYGALTSD 3313
Query: 98 EGIYTCQEILNVTQWFQVWLQVASGPYQIE-----VHIVATGTLPNGTLYAAR-----GS 147
G YTC VA+ P E +++ T T+ A + +
Sbjct: 3314 TGKYTC---------------VATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDT 3358
Query: 148 QVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVN-FFSLLLISPNLQGNYTCLALNQ 206
++ C ++ PPP + W L S L ++ + YTC+A N+
Sbjct: 3359 SINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNR 3418
Query: 207 LSKRHRKVTTELLVYYPPPSAPQCWAQ---MASGSFMLQLTCRWDGGYPDPDFLWIEE-- 261
++ L V+ PP + + GS + C DG P P W+ +
Sbjct: 3419 AGVDNKHYN--LQVFAPPNMDNSMGTEEITVLKGS-STSMACITDGT-PAPSMAWLRDGQ 3474
Query: 262 PGGV---IVGKSKLGVEMLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSLLSEPM 318
P G+ + + V L +++ D K+ C+ S+ G S + + P +
Sbjct: 3475 PLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEE 3534
Query: 319 K---TCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIH 375
+ + LTC SG P K+ W+++ +P P + + T G L I
Sbjct: 3535 HEEISVIVNNPLELTCIASGI-PAPKMTWMKD-GRP----LPQTDQVQTLGG-GEVLRI- 3586
Query: 376 NCSQDLDEGYYICRADSPVGVREMEIWLSVKEPLNIGG 413
+ +Q D G Y C A SP G + E + V P NI G
Sbjct: 3587 STAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAG 3624
Score = 51.2 bits (121), Expect = 2e-06
Identities = 60/278 (21%), Positives = 110/278 (39%), Gaps = 26/278 (9%)
Query: 149 VDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISPNLQ--GNYTCLALNQ 206
++ C+ + PPP + W + E G + +N L++ + G Y C+A N
Sbjct: 1752 LELDCHVTGSPPPTI-MWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANT 1810
Query: 207 LSKRHRKVTTELLVYYPPPSAPQCWAQMASGSFM-LQLTCRWDGGYPDPDFLWIEEPGGV 265
H+K E+ V+ PP ++ + + L C G P+P W+++ V
Sbjct: 1811 AGD-HKK-EFEVTVHVPPTIKSSGLSERVVVKYKPVALQC-IANGIPNPSITWLKDDQPV 1867
Query: 266 IVGKSKLGVE------MLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSLLSEPMK 319
+ L ++ ++++ L D ++ CV ++ G E+ + + P L + K
Sbjct: 1868 NTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAG-ETQQHIQLHVHEPPSLEDAGK 1926
Query: 320 ----TCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIH 375
T V L C+ +G P I W ++ ++ S+ GQ +
Sbjct: 1927 MLNETVLVSNPVQLECKAAG-NPVPVITWYKD----NRLLSGSTSMTFLNRGQIIDI--- 1978
Query: 376 NCSQDLDEGYYICRADSPVGVREMEIWLSVKEPLNIGG 413
+Q D G Y C A + G E+ L V +I G
Sbjct: 1979 ESAQISDAGIYKCVAINSAGATELFYSLQVHVAPSISG 2016
Score = 49.3 bits (116), Expect = 9e-06
Identities = 77/355 (21%), Positives = 134/355 (37%), Gaps = 52/355 (14%)
Query: 88 LHIESLSLGDEGIYTCQEILNVTQWFQVWLQVASGPYQIEVH----IVATGTLPNGTLYA 143
L ++++ + D G Y C + NV + Y + VH I+ P
Sbjct: 2348 LQLKNIHVSDTGRYVCVAV-NVAG-------MTDKKYDLSVHAPPSIIGNHRSPENISVV 2399
Query: 144 ARGSQVDFSCNSSSRPPPVVEW----WFQALNSSSESFGHNLTVNFFSLLLISPNLQGNY 199
+ S V +C +S P P + W W +L++S L+ + G Y
Sbjct: 2400 EKNS-VSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGG---RMLRLMQTTMEDAGQY 2455
Query: 200 TCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQ--MASGSFMLQLTCRWDGGYPDPDFL 257
TC+ N + + +LV PP + + + LTC G P P+
Sbjct: 2456 TCVVRNAAGEERKIFGLSVLV--PPHIVGENTLEDVKVKEKQSVTLTCEVTGN-PVPEIT 2512
Query: 258 WI--------EEPGGVIVGKSKLGVEMLSESQLSDGKKFKCVTSHIVGPESGASCMVQIR 309
W +E +I G L ++ Q+ ++ C+ S G +S + +
Sbjct: 2513 WHKDGQPLQEDEAHHIISGGRFL---QITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFV 2569
Query: 310 GPSLLSEPMK------TCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLI 363
P++ T +L C+ +YPPA I W ++ T E S+R++
Sbjct: 2570 SPTIAGVGSDGNPEDVTVILNSPTSLVCEAY-SYPPATITWFKDGTPLE-----SNRNIR 2623
Query: 364 TQDGQNSTLTIHNCSQDLDEGYYICRADSPVG--VREMEIWLSVKEPLNIGGIVG 416
G TL I N +D + G Y C A + G ++ E+ + + +N G + G
Sbjct: 2624 ILPG-GRTLQILNAQED-NAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWG 2676
Score = 48.9 bits (115), Expect = 1e-05
Identities = 92/406 (22%), Positives = 152/406 (37%), Gaps = 74/406 (18%)
Query: 38 ENVTLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSLVDATSLHIESLSLGD 97
E VTL C S +TW + + P PR + + + S+ I D
Sbjct: 1095 EEVTLPCEVKSLPPPIITWAKETQ----------LISPFSPRHTFLPSGSMKITETRTSD 1144
Query: 98 EGIYTCQEIL---NVTQWFQVWLQVAS----GPYQIEVHIVATGTLPNGTLYAARGSQVD 150
G+Y C NVTQ ++ + V GP ++V + G +VD
Sbjct: 1145 SGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQV---------------GQRVD 1189
Query: 151 FSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLI---SPNLQGNYTCLALNQL 207
CN+ P PV+ W S+ G + N L I +P+ G YTC+A N
Sbjct: 1190 IPCNAQGTPLPVITW--SKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIA 1247
Query: 208 SKRHRKVTTELLVYYPP------PSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWIEE 261
++T L V PP P + + + ++ C G P P W+
Sbjct: 1248 GTDETEIT--LHVQEPPTVEDLEPPYNTTFQERVANQ-RIEFPCP-AKGTPKPTIKWLHN 1303
Query: 262 PGGVIVGKSKLGVEMLSESQL--------SDGKKFKCVTSHIVGPESGASCMVQIRGPSL 313
G + G+ G+ +L + L D ++ CV + G + +++ P +
Sbjct: 1304 -GRELTGREP-GISILEDGTLLVIASVTPYDNGEYICVAVNEAG-TTERKYNLKVHVPPV 1360
Query: 314 LSEPMKTCFTGGNVTLT------CQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDG 367
+ + K T +V L C+V G P I+W ++ Q + SS +G
Sbjct: 1361 IKD--KEQVTNVSVLLNQLTNLFCEVEGT-PSPIIMWYKDNVQ----VTESSTIQTVNNG 1413
Query: 368 QNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEPLNIGG 413
+ L + + + D G Y C+A + G + + V P I G
Sbjct: 1414 K--ILKLFRATPE-DAGRYSCKAINIAGTSQKYFNIDVLVPPTIIG 1456
Score = 48.1 bits (113), Expect = 2e-05
Identities = 53/232 (22%), Positives = 99/232 (42%), Gaps = 24/232 (10%)
Query: 194 NLQGNYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASG--SFMLQLTCRWDGGY 251
N +G Y C N K+ + + +L +Y PP S + +++L C G
Sbjct: 1518 NDKGRYQCTVSNAAGKQAKDI--KLTIYIPPSIKGGNVTTDISVLINSLIKLECE-TRGL 1574
Query: 252 PDPDFLWIEEPGGVIVGKSKLGVEM-----LSESQLSDGKKFKCVTSHIVGPESGASCMV 306
P P W ++ ++ L ++ + +Q+SD + C +++ G S V
Sbjct: 1575 PMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAE-KSFHV 1633
Query: 307 QIRGPSL----LSEPM-KTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRH 361
+ P + L+ P+ K ++TL C+ +G P + WL++ V ++ +
Sbjct: 1634 DVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPI-LTWLKD----GVPVKANDNI 1688
Query: 362 LITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEPLNIGG 413
I G+ + +Q++D G YIC A S G +E++ + V P I G
Sbjct: 1689 RIEAGGKKLEIM---SAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEG 1737
Score = 47.0 bits (110), Expect = 4e-05
Identities = 84/358 (23%), Positives = 136/358 (37%), Gaps = 43/358 (12%)
Query: 77 EPRFSLVDATS-LHIESLSLGDEGIYTCQEILNVTQWFQVWLQVASGPYQIEVHIVAT-- 133
+P S+ + S L IE + D G YTC E NV Y + + +
Sbjct: 2147 KPGLSISENRSVLKIEDAQVQDTGRYTC-EATNVAG-------KTEKNYNVNIWVPPNIG 2198
Query: 134 GTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISP 193
G+ L G+ + C SS PPP + W + ++S G ++ L IS
Sbjct: 2199 GSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISI 2258
Query: 194 NLQGN---YTCLALNQLSKRHRKVTTELLVYYPPP---SAPQCWAQMASGSFMLQLTCRW 247
+ + Y+C+A N ++ L VY P S + + + L C
Sbjct: 2259 AEKSDAALYSCVASNVAGTAKKEY--NLQVYIRPTITNSGSHPTEIIVTRGKSISLECEV 2316
Query: 248 DGGYPDPDFLWIEEPGGVIVGKSKLGVEMLSESQL--------SDGKKFKCVTSHIVGPE 299
G P P W+++ +I K GVE+L E + SD ++ CV ++ G
Sbjct: 2317 Q-GIPPPTVTWMKDGHPLIKAK---GVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMT 2372
Query: 300 SGASCMVQIRGPSLL----SEPMKTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVII 355
+ PS++ S + +V+LTC+ SG P I W ++ +
Sbjct: 2373 DKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEASG-IPLPSITWFKDGWP----V 2427
Query: 356 QPSSRHLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEPLNIGG 413
S+ I G+ L + + + D G Y C + G LSV P +I G
Sbjct: 2428 SLSNSVRILSGGR--MLRLMQTTME-DAGQYTCVVRNAAGEERKIFGLSVLVPPHIVG 2482
Score = 46.6 bits (109), Expect = 6e-05
Identities = 70/283 (24%), Positives = 101/283 (35%), Gaps = 38/283 (13%)
Query: 146 GSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHN-LTVNFFSLLLISPNLQGNYTCLAL 204
G +V C S PPP++ W + S S H L + + G Y C+A
Sbjct: 1094 GEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVAT 1153
Query: 205 NQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRWD-----GGYPDPDFLWI 259
N + V +L V+ PP Q +Q+ R D G P P W
Sbjct: 1154 NIAGNVTQAV--KLNVHVPPK------IQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWS 1205
Query: 260 EEPGGVIVG-----KSKLGVEMLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSL- 313
+ ++V + G + ++ SD + CV ++I G + + P++
Sbjct: 1206 KGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVE 1265
Query: 314 -LSEPMKTCF----TGGNVTLTCQVSGAYPPAKILWLRN---LTQPEVIIQPSSRHLITQ 365
L P T F + C G P I WL N LT E I I +
Sbjct: 1266 DLEPPYNTTFQERVANQRIEFPCPAKGT-PKPTIKWLHNGRELTGREPGIS------ILE 1318
Query: 366 DGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEP 408
DG TL + D G YIC A + G E + L V P
Sbjct: 1319 DG---TLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVP 1358
Score = 38.9 bits (89), Expect = 0.012
Identities = 92/434 (21%), Positives = 153/434 (35%), Gaps = 94/434 (21%)
Query: 28 LEAVVIGEVHENVTLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSLVDATS 87
LE V + E ++VTL C ++TW+++ L+ E +
Sbjct: 2486 LEDVKVKE-KQSVTLTCEVTGNPVPEITWHKDGQP----------LQEDEAHHIISGGRF 2534
Query: 88 LHIESLSLGDEGIYTCQEILNVTQWFQVWLQVASGP-------YQIEVHIVAT--GTLPN 138
L I ++ + G YTC +AS P + + V + T G +
Sbjct: 2535 LQITNVQVPHTGRYTC---------------LASSPAGHKSRSFSLNVFVSPTIAGVGSD 2579
Query: 139 GT---LYAARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTV----NFFSLLLI 191
G + S C + S PP + W+ S N+ + +L
Sbjct: 2580 GNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESN---RNIRILPGGRTLQILNA 2636
Query: 192 SPNLQGNYTCLALNQLSKRHRKVTTELLVYYPPP-SAPQCWAQMASGSFM-------LQL 243
+ G Y+C+A N+ + + E+ VY PP + W S + L L
Sbjct: 2637 QEDNAGRYSCVATNEAGEMIKHY--EVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTL 2694
Query: 244 TCRWDGGYPDPDFLWIEEPGGVIVGKSKLGVE------MLSESQLSDGKKFKCVTSHIVG 297
C P W ++ G + + + + E+Q+SD ++ CV S+I G
Sbjct: 2695 ECE-AYAIPSASLSWYKD-GQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAG 2752
Query: 298 PESGASCMVQIRGP---SLLSEPMKTCFTGGN-----------VTLTCQVSGAYPPAKIL 343
E V I+ P L E TG N ++L C+ + A PP +
Sbjct: 2753 -EDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAA-PPPTLT 2810
Query: 344 WLRN----LTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREM 399
W ++ + +V+I P R L I + D G Y C A + G +
Sbjct: 2811 WYKDGHPLTSSDKVLILPGGR----------VLQIPRAKVE-DAGRYTCVAVNEAGEDSL 2859
Query: 400 EIWLSVKEPLNIGG 413
+ + V P I G
Sbjct: 2860 QYDVRVLVPPIIKG 2873
>gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens]
Length = 1215
Score = 73.6 bits (179), Expect = 4e-13
Identities = 88/365 (24%), Positives = 137/365 (37%), Gaps = 53/365 (14%)
Query: 54 VTWYRNNSEPVFL-LSSNSSLRPAEPRFSLVDATSLHIESLSLGDEGIYTCQEILNVTQW 112
VTW R + +P+ L L + R +P D+ L ES++ D+ Y C E NV
Sbjct: 700 VTWRRGDGQPLGLRLGAGRGSRSRQP-----DSGVLFFESVAPEDQAPYVC-EARNVF-- 751
Query: 113 FQVWLQVASGPYQIEVHIVATGTLPNG------TLYAARGSQVDFSCNSSSRPPPVVEWW 166
G Q E ++ TG P T+ G V C + P W
Sbjct: 752 ---------GKVQAEARLIVTGHAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHW 802
Query: 167 FQALNSSSESFGHNLTVNFFSLLLISPNLQ---GNYTCLALNQLSKRHRKVTTELLVYYP 223
+ H++ + L + LQ G Y+C+A N +HR V EL+V P
Sbjct: 803 LKDGRPLPPGSRHSIRAD--GSLHLDRALQEHAGRYSCVATNTAGSQHRDV--ELVVQVP 858
Query: 224 PPSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWIEEPG-----GVIVGKSKLGVEMLS 278
P P + + L C G P P W +E G SK G +++
Sbjct: 859 PRIHPTATHHITNEGVPASLPCV-ASGVPAPTITWTKETNALTSRGPHYNVSKEGTLLIA 917
Query: 279 ESQLSDGKKFKCVTSHIVGPES-------GASCMVQIRGPSLLSEPMK-TCFTGGNVTLT 330
+ D + C ++ VG S + + G + P++ T G VTL
Sbjct: 918 QPSAQDAGAYVCTATNTVGFSSQEMRLSVNTKPRIHMNGSRNANVPLQVTAKAGEEVTLD 977
Query: 331 CQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQDLDEGYYICRA 390
C+ G+ PP + W ++ I ++R+ + G + Q D G+Y C A
Sbjct: 978 CEAKGS-PPPLVTWTKDSRPVPPI---TNRYGLLPSGSLRLAQV----QVGDSGHYECTA 1029
Query: 391 DSPVG 395
+P G
Sbjct: 1030 SNPAG 1034
Score = 60.1 bits (144), Expect = 5e-09
Identities = 90/393 (22%), Positives = 137/393 (34%), Gaps = 47/393 (11%)
Query: 28 LEAVVIGEVHENVTLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSLVDATS 87
+ AVV+ V E L C +V WYR E + +SS +
Sbjct: 586 VNAVVLVAVGEEAVLVCEASGVPPPRVIWYRGGLEMILAPEGSSSGK------------- 632
Query: 88 LHIESLSLGDEGIYTCQEILNVTQWF-QVWLQVASGPYQIEVHIVATGTLPNGTLYAARG 146
L I + D G YTC+ + + ++ L V P E+ T L L A
Sbjct: 633 LRIPAAQERDAGTYTCRAVNELGDASAEIQLAVGHAPQLTELPRDVTVELGRSALLA--- 689
Query: 147 SQVDFSCNSSSRPPPVVEW---------WFQALNSSSESFGHNLTVNFFSLLLISPNLQG 197
C ++ RPPP V W S S + V FF ++P Q
Sbjct: 690 ------CRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFE--SVAPEDQA 741
Query: 198 NYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFL 257
Y C A N K + + + PP A + L C G P P+
Sbjct: 742 PYVCEARNVFGKVQAEARLIVTGHAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERH 801
Query: 258 WIEE----PGGVIVGKSKLGVEMLSESQLSDGKKFKCVTSHIVGPE-SGASCMVQIRGPS 312
W+++ P G G L + ++ CV ++ G + +VQ+
Sbjct: 802 WLKDGRPLPPGSRHSIRADGSLHLDRALQEHAGRYSCVATNTAGSQHRDVELVVQVPPRI 861
Query: 313 LLSEPMKTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTL 372
+ G +L C SG P I W + + + + ++++G TL
Sbjct: 862 HPTATHHITNEGVPASLPCVASGV-PAPTITWTK---ETNALTSRGPHYNVSKEG---TL 914
Query: 373 TIHNCSQDLDEGYYICRADSPVGVREMEIWLSV 405
I S D G Y+C A + VG E+ LSV
Sbjct: 915 LIAQPSAQ-DAGAYVCTATNTVGFSSQEMRLSV 946
Score = 53.9 bits (128), Expect = 4e-07
Identities = 74/337 (21%), Positives = 126/337 (37%), Gaps = 32/337 (9%)
Query: 77 EPRFSLVDATSLHIESLSLGDEGIYTCQEILNV-TQWFQVWLQVASGPYQIEVHIVATGT 135
E F +S I S +EG Y C + T + + V P Q+
Sbjct: 353 ERHFQESGNSSWEILRASKAEEGTYECTAVSRAGTGRAKAQIVVTDPPPQL--------- 403
Query: 136 LPNGTLYAARGSQVDFSCNSSSRPPPVVEWW--FQALNSSSESFGHNLTVNFFSLLLISP 193
+P + + G SC P + W ++ L +S+ ++ + I P
Sbjct: 404 VPAPNVTVSPGETAVLSCRVLGEAPYNLTWVRDWRVLPASTGRVAQLADLSL-EISGIIP 462
Query: 194 NLQGNYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPD 253
G Y C+A N + + + LLV P + +Q S ++++C GYP
Sbjct: 463 TDGGRYQCVASN--ANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCS-ASGYPT 519
Query: 254 PDFLWIEEPGGVI----VGKSKLGVEMLSESQLSDGKKFKCVTSHIVGPESGASCMVQIR 309
P W E + + G ++ D + C ++ VG + +
Sbjct: 520 PHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTLYYTD 579
Query: 310 GPSLLS-EPMKTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQ 368
PS+ + + G L C+ SG PP +++W R E+I+ P +G
Sbjct: 580 PPSVSAVNAVVLVAVGEEAVLVCEASGV-PPPRVIWYRGGL--EMILAP--------EGS 628
Query: 369 NSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSV 405
+S +Q+ D G Y CRA + +G EI L+V
Sbjct: 629 SSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAV 665
Score = 51.6 bits (122), Expect = 2e-06
Identities = 55/241 (22%), Positives = 101/241 (41%), Gaps = 20/241 (8%)
Query: 186 FSLLLISPNLQGNYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSFMLQLTC 245
+ +L S +G Y C A+++ K +++V PPP S L+C
Sbjct: 364 WEILRASKAEEGTYECTAVSRAGTGRAKA--QIVVTDPPPQLVPAPNVTVSPGETAVLSC 421
Query: 246 RWDGGYPDPDFLWIEE------PGGVIVGKSKLGVEMLSESQLSDGKKFKCVTSHIVGPE 299
R G P + W+ + G + + L +E +S +DG +++CV S+ G
Sbjct: 422 RVLGEAPY-NLTWVRDWRVLPASTGRVAQLADLSLE-ISGIIPTDGGRYQCVASNANGVT 479
Query: 300 SGASCMVQIRGPSLLSEPMKTCFTGG-NVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPS 358
+ ++ P + F+ G V ++C SG YP I W R + + + + S
Sbjct: 480 RASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSASG-YPTPHISWSR---ESQALQEDS 535
Query: 359 SRHLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEPLNIGGIVGTI 418
H+ Q TL I + + D G Y C+A + VG + + L +P ++ + +
Sbjct: 536 RIHVDAQ----GTLIIQGVAPE-DAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVV 590
Query: 419 V 419
+
Sbjct: 591 L 591
Score = 29.6 bits (65), Expect = 7.3
Identities = 34/147 (23%), Positives = 55/147 (37%), Gaps = 5/147 (3%)
Query: 71 SSLRPAEPRFSLVDATSLHIESLSLGDEGIYTCQEILNVTQWFQVWLQVASGPYQIEVHI 130
++L P +++ +L I S D G Y C V Q + +I ++
Sbjct: 897 NALTSRGPHYNVSKEGTLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNTKPRIHMNG 956
Query: 131 VATGTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWW--FQALNSSSESFGHNLTVNFFSL 188
+P + A G +V C + PPP+V W + + + +G L L
Sbjct: 957 SRNANVPL-QVTAKAGEEVTLDCEAKGSPPPLVTWTKDSRPVPPITNRYG-LLPSGSLRL 1014
Query: 189 LLISPNLQGNYTCLALNQL-SKRHRKV 214
+ G+Y C A N S HR V
Sbjct: 1015 AQVQVGDSGHYECTASNPAGSASHRYV 1041
>gi|48476182 roundabout, axon guidance receptor, homolog 3 [Homo
sapiens]
Length = 1386
Score = 72.0 bits (175), Expect = 1e-12
Identities = 80/290 (27%), Positives = 123/290 (42%), Gaps = 38/290 (13%)
Query: 141 LYAARGSQVDFSCNSSSRPPPVVEWWFQALNSSS---ESFGHNLTVNFFSLLLISPNL-- 195
L +RG C + RP P +EW+ ++ + H L + S L P +
Sbjct: 73 LLVSRGEPATLPCRAEGRPRPNIEWYKNGARVATVREDPRAHRLLLP--SGALFFPRIVH 130
Query: 196 -------QGNYTCLALNQL-SKRHRKVTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRW 247
+G YTC+A N L + R + E+ V +A G + L C
Sbjct: 131 GRRARPDEGVYTCVARNYLGAAASRNASLEVAVLRDDFRQSPGNVVVAVGEPAV-LECVP 189
Query: 248 DGGYPDPDFLW-------IEEPGGVIVGKSKLGVEMLSESQLSDGKKFKCVTSHIVGP-E 299
G+P+P W EE G + + KL M+S + SD + CV S++ G E
Sbjct: 190 PRGHPEPSVSWRKDGARLKEEEGRITIRGGKL---MMSHTLKSDAGMYVCVASNMAGERE 246
Query: 300 SGASCMVQIRGPSLLSEPM-KTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPS 358
S A+ ++ + PS L P+ + VT C+V G PP ++ W + + P+
Sbjct: 247 SAAAEVMVLERPSFLRRPVNQVVLADAPVTFLCEVKGD-PPPRLRWRKEDGE-----LPT 300
Query: 359 SRHLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEP 408
R+ I D +L I + S + DEG Y C A++ VG E LSV P
Sbjct: 301 GRYEIRSD---HSLWIGHVSAE-DEGTYTCVAENSVGRAEASGSLSVHVP 346
Score = 70.9 bits (172), Expect = 3e-12
Identities = 92/385 (23%), Positives = 148/385 (38%), Gaps = 37/385 (9%)
Query: 38 ENVTLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSLVDATSLHIESLSLGD 97
E TL C R + WY+N + + + R P +L +H + D
Sbjct: 79 EPATLPCRAEGRPRPNIEWYKNGARVATVREDPRAHRLLLPSGALFFPRIVHGRR-ARPD 137
Query: 98 EGIYTC--QEILNVTQWFQVWLQVASGPYQIEVHIVATGTLPN-GTLYAARGSQVDFSC- 153
EG+YTC + L AS +EV ++ + G + A G C
Sbjct: 138 EGVYTCVARNYLGA---------AASRNASLEVAVLRDDFRQSPGNVVVAVGEPAVLECV 188
Query: 154 NSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISPNLQ---GNYTCLALNQLSKR 210
P P V W E +T+ L++S L+ G Y C+A N +R
Sbjct: 189 PPRGHPEPSVSWRKDGARLKEEE--GRITIR-GGKLMMSHTLKSDAGMYVCVASNMAGER 245
Query: 211 HRKVTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWIEEPGGVIVGKS 270
E++V P + Q+ + C G P P W +E G + G+
Sbjct: 246 -ESAAAEVMVLERPSFLRRPVNQVVLADAPVTFLCEVKGD-PPPRLRWRKEDGELPTGRY 303
Query: 271 KLGVE---MLSESQLSDGKKFKCVTSHIVG-PESGASCMVQIRGPSLLSEPM-KTCFTGG 325
++ + + D + CV + VG E+ S V + P L+++P + G
Sbjct: 304 EIRSDHSLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHV-PPQLVTQPQDQMAAPGE 362
Query: 326 NVTLTCQVSGAYPPAKILWLRNLTQ----PEVIIQPSSRHLITQDGQNSTLTIHNCSQDL 381
+V C+ G PPA I W + +Q P +QP+ R ++ GQ + + Q
Sbjct: 363 SVAFQCETKGNPPPA-IFWQKEGSQVLLFPSQSLQPTGRFSVSPRGQLNITAV----QRG 417
Query: 382 DEGYYICRADSPVGVREMEIWLSVK 406
D GYY+C+A S G + L +K
Sbjct: 418 DAGYYVCQAVSVAGSILAKALLEIK 442
Score = 62.0 bits (149), Expect = 1e-09
Identities = 72/288 (25%), Positives = 111/288 (38%), Gaps = 51/288 (17%)
Query: 149 VDFSCNSSSRPPPVVEWWFQALNSSSESF----GHNLTVNFFSLLLISPNLQGNYTCLAL 204
V F C PPP + W + + + H+L + +S +G YTC+A
Sbjct: 275 VTFLCEVKGDPPPRLRWRKEDGELPTGRYEIRSDHSLWIGH-----VSAEDEGTYTCVAE 329
Query: 205 NQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWIEEPGG 264
N + + + + L V+ PP Q QMA+ + C G P P W +E
Sbjct: 330 NSVGRA--EASGSLSVHVPPQLVTQPQDQMAAPGESVAFQCETKGN-PPPAIFWQKEGSQ 386
Query: 265 VIVGKSKL------------GVEMLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPS 312
V++ S+ G ++ Q D + C + G A +++I+G S
Sbjct: 387 VLLFPSQSLQPTGRFSVSPRGQLNITAVQRGDAGYYVCQAVSVAGSIL-AKALLEIKGAS 445
Query: 313 LLSEPM--------KTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLIT 364
L P +T G +V L C+V+G QP V + + L
Sbjct: 446 LDGLPPVILQGPANQTLVLGSSVWLPCRVTGN------------PQPSVRWKKDGQWLQG 493
Query: 365 QDGQ-----NSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKE 407
D Q N TL I N Q++D G+Y C A S G WL ++E
Sbjct: 494 DDLQFKTMANGTLYIANV-QEMDMGFYSCVAKSSTGEATWSGWLKMRE 540
Score = 37.7 bits (86), Expect = 0.027
Identities = 35/128 (27%), Positives = 48/128 (37%), Gaps = 5/128 (3%)
Query: 38 ENVTLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSLVDATSLHIESLSLGD 97
E+V C + W + S+ LL + SL+P RFS+ L+I ++ GD
Sbjct: 362 ESVAFQCETKGNPPPAIFWQKEGSQ--VLLFPSQSLQPTG-RFSVSPRGQLNITAVQRGD 418
Query: 98 EGIYTCQEILNVTQWFQVWLQVASGPYQIEVHIVATGTLPNGTLYAARGSQVDFSCNSSS 157
G Y CQ + L G + V N TL GS V C +
Sbjct: 419 AGYYVCQAVSVAGSILAKALLEIKGASLDGLPPVILQGPANQTL--VLGSSVWLPCRVTG 476
Query: 158 RPPPVVEW 165
P P V W
Sbjct: 477 NPQPSVRW 484
>gi|109150416 peroxidasin [Homo sapiens]
Length = 1479
Score = 69.3 bits (168), Expect = 8e-12
Identities = 74/298 (24%), Positives = 120/298 (40%), Gaps = 56/298 (18%)
Query: 36 VHENVTLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSLVDATSLHIESLSL 95
V E+VTL C +++W R + P+ P +PR ++ + L+I+++
Sbjct: 355 VGESVTLECSATGHPPPRISWTRGDRTPL----------PVDPRVNITPSGGLYIQNVVQ 404
Query: 96 GDEGIYTCQEILNVTQWFQVWLQVASGPYQIEVHIVATGTLPNGTLYAARGSQVDFSCNS 155
GD G Y C N+ I V + T+ G VDF C +
Sbjct: 405 GDSGEYACSATNNIDS--------VHATAFIIVQALPQFTVTPQDRVVIEGQTVDFQCEA 456
Query: 156 SSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISPNL---------QGNYTCLALNQ 206
PPPV+ W G L+V+ L+L S L QG Y C A+N
Sbjct: 457 KGNPPPVIAW---------TKGGSQLSVDRRHLVLSSGTLRISGVALHDQGQYECQAVNI 507
Query: 207 LSKRHRKVTTELLVYYPPPSAPQCWAQMASGSFM-----LQLTCRWDGGYPDPDFLWIEE 261
+ +KV L V P +A + S + + +QL C G P+P W ++
Sbjct: 508 IGS--QKVVAHLTV---QPRVTPVFASIPSDTTVEVGANVQLPCS-SQGEPEPAITWNKD 561
Query: 262 PGGVIV---GK---SKLGVEMLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSL 313
GV V GK S G +++ +D +++CV + +G S S ++ + P +
Sbjct: 562 --GVQVTESGKFHISPEGFLTINDVGPADAGRYECVARNTIGSAS-VSMVLSVNVPDV 616
Score = 64.3 bits (155), Expect = 3e-10
Identities = 91/368 (24%), Positives = 145/368 (39%), Gaps = 41/368 (11%)
Query: 53 QVTWYRNNSEPVFLLSSNSSLRPAEPRFSLVDATSLHIESLSLGDEGIYTC--QEILNVT 110
++ W RNN+E LS + + R +L+D +L I++ D+GIY C + +
Sbjct: 276 EIIWLRNNNE----LSMKT-----DSRLNLLDDGTLMIQNTQETDQGIYQCMAKNVAGEV 326
Query: 111 QWFQVWLQVASGPYQIEVHIVATGTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWWFQAL 170
+ +V L+ P + T + G V C+++ PPP + W
Sbjct: 327 KTQEVTLRYFGSPAR------PTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTRGDR 380
Query: 171 NSSSESFGHNLTVNFFSLLLISPNLQGN---YTCLALNQLSKRHRKVTTELLVYYPPPSA 227
N+T + L I +QG+ Y C A N + H T ++V P
Sbjct: 381 TPLPVDPRVNITPS--GGLYIQNVVQGDSGEYACSATNNIDSVH--ATAFIIVQALPQFT 436
Query: 228 PQCWAQMASGSFMLQLTCRWDGGYPDPDFLWIEEPGGVIVGKSKL----GVEMLSESQLS 283
++ + C G P P W + + V + L G +S L
Sbjct: 437 VTPQDRVVIEGQTVDFQCEAKGN-PPPVIAWTKGGSQLSVDRRHLVLSSGTLRISGVALH 495
Query: 284 DGKKFKCVTSHIVGPES-GASCMVQIR-GPSLLSEPMKTCF-TGGNVTLTCQVSGAYPPA 340
D +++C +I+G + A VQ R P S P T G NV L C G PA
Sbjct: 496 DQGQYECQAVNIIGSQKVVAHLTVQPRVTPVFASIPSDTTVEVGANVQLPCSSQGEPEPA 555
Query: 341 KILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREME 400
I W ++ Q + S + I+ +G LTI++ D G Y C A + +G +
Sbjct: 556 -ITWNKDGVQ----VTESGKFHISPEG---FLTINDVG-PADAGRYECVARNTIGSASVS 606
Query: 401 IWLSVKEP 408
+ LSV P
Sbjct: 607 MVLSVNVP 614
Score = 48.9 bits (115), Expect = 1e-05
Identities = 43/123 (34%), Positives = 60/123 (48%), Gaps = 19/123 (15%)
Query: 311 PSLLSEPMKTCFTGGN-VTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQN 369
P + SEP T GN V TC+ G P +I+WLRN E+ ++ SR + DG
Sbjct: 246 PRITSEPQDADVTSGNTVYFTCRAEGN-PKPEIIWLRN--NNELSMKTDSRLNLLDDG-- 300
Query: 370 STLTIHNCSQDLDEGYYICRADSPVG-VREMEIWLS----------VKEPLNIGGIVGTI 418
TL I N +Q+ D+G Y C A + G V+ E+ L V +P N +VG
Sbjct: 301 -TLMIQN-TQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGES 358
Query: 419 VSL 421
V+L
Sbjct: 359 VTL 361
Score = 47.8 bits (112), Expect = 3e-05
Identities = 65/274 (23%), Positives = 106/274 (38%), Gaps = 26/274 (9%)
Query: 146 GSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISPNL---QGNYTCL 202
G+ V F+C + P P + W + N S L + L+I QG Y C+
Sbjct: 260 GNTVYFTCRAEGNPKPEI-IWLRNNNELSMKTDSRLNLLDDGTLMIQNTQETDQGIYQCM 318
Query: 203 ALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSFM----LQLTCRWDGGYPDPDFLW 258
A N + + T L Y+ P+ P Q + + + L C G+P P W
Sbjct: 319 AKNVAGEVKTQEVT--LRYFGSPARPTFVIQPQNTEVLVGESVTLECS-ATGHPPPRISW 375
Query: 259 IEE-----PGGVIVGKSKLGVEMLSESQLSDGKKFKC-VTSHIVGPESGASCMVQIRGPS 312
P V + G + D ++ C T++I + A +VQ
Sbjct: 376 TRGDRTPLPVDPRVNITPSGGLYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQALPQF 435
Query: 313 LLSEPMKTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTL 372
++ + G V C+ G PP I W + +Q V RHL+ G TL
Sbjct: 436 TVTPQDRVVIEGQTVDFQCEAKG-NPPPVIAWTKGGSQLSV----DRRHLVLSSG---TL 487
Query: 373 TIHNCSQDLDEGYYICRADSPVGVREMEIWLSVK 406
I + D+G Y C+A + +G +++ L+V+
Sbjct: 488 RISGVALH-DQGQYECQAVNIIGSQKVVAHLTVQ 520
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 68.6 bits (166), Expect = 1e-11
Identities = 100/410 (24%), Positives = 154/410 (37%), Gaps = 61/410 (14%)
Query: 38 ENVTLHCGNISGLRGQVTWYRN-NSEPVFLLSSNSSLRPAEPRFSLVDATSLHIESLSLG 96
EN +L C + QVTW + +SEP+ +P ++++ SL + S+S
Sbjct: 1222 ENASLPCPARGTPKPQVTWRKGPSSEPLH----------GQPGVAVLEEGSLFLASVSPA 1271
Query: 97 DEGIYTCQEILNVTQWFQVWLQVASGPYQIEVHIVATGTLPNGTLYAARGSQVDFSCNSS 156
D G Y CQ V + V P I G N + A G + C+++
Sbjct: 1272 DSGDYECQATNEVGSTSRRAKLVVYVPPSIR----EDGRKANVSGMA--GQSLTLECDAN 1325
Query: 157 SRPPPVVEWWFQALNSS--------------SESFGHNLTVNFFSLLLISPNLQ----GN 198
P P + W A + GH L SL P +Q G
Sbjct: 1326 GFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHF--PRIQEGDSGL 1383
Query: 199 YTCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASG--SFMLQLTCRWDGGYPDPDF 256
Y+C A NQ R LLV PP AQ G ++L C W G P P
Sbjct: 1384 YSCRAENQAGTAQRDF--HLLVLTPPSVLGAGAAQEVLGLAGADVELQC-WTSGVPTPQV 1440
Query: 257 LWIEEPGGVIVGKSKLGVE------MLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRG 310
W ++ V+ G L V+ ++ S + D +++CV G ++ +++
Sbjct: 1441 EWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQCVAFSPAGQQA-RDFQLRVHA 1499
Query: 311 PSLLSEPMKT----CFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQD 366
P + +T V L C+ G P I W ++ ++ S++ + T+
Sbjct: 1500 PPTIWGSNETGEVAVMEDHLVQLLCEARGV-PTPNITWFKD----GALLPTSTKVVYTRG 1554
Query: 367 GQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEPLNIGGIVG 416
G+ L +Q D G Y C+A + VG E L V P I G G
Sbjct: 1555 GRQLQL---GRAQSSDAGVYTCKASNAVGAAEKATRLDVYVPPTIEGAGG 1601
Score = 67.4 bits (163), Expect = 3e-11
Identities = 95/370 (25%), Positives = 147/370 (39%), Gaps = 52/370 (14%)
Query: 74 RPAEPRFSLVDA---TSLHIESLSLGDEGIYTCQEILNV-TQWFQVWLQV----ASGPYQ 125
RPAE + A T+LHI+ + L G++ CQ T +V + V A G +
Sbjct: 1728 RPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLE 1787
Query: 126 IEVHIVATGTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNF 185
+ + G + + AA V + + PP+VE W + E G + +
Sbjct: 1788 VPIGQYHWGXEHHSSFPAACDPPVHRGWGAHPK-PPLVEGWCSPGSLWGEPTGIPVAYSL 1846
Query: 186 ---FSLLLISPNLQGNYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSFMLQ 242
+ + +G YTC A N + R+V ++LV PP P + + +
Sbjct: 1847 PPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLV--PPNIEPGPVNKAVLENASVT 1904
Query: 243 LTCRWDGGYPDPDFLWIEEPGGVIVGKSKLGVEM--------LSESQLSDGKKFKCVTSH 294
L C G P PD W + V S +GV + + ++QLSD ++CV S+
Sbjct: 1905 LEC-LASGVPPPDVSWFKGHQPV---SSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASN 1960
Query: 295 IVGPES---GASCMVQIR--------GPSLLSEPMKTCFTGGNVTLTCQVSGAYPPAKIL 343
+ G G V R GP L++ P V LTC +GA P ++
Sbjct: 1961 VAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTP---------VRLTCNATGA-PSPTLM 2010
Query: 344 WLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWL 403
WL++ P + + G+ TL S D G Y C A S VG ++ L
Sbjct: 2011 WLKDGNPVSPAGTPGLQ--VFPGGRVLTLASARAS---DSGRYSCVAVSAVGEDRQDVVL 2065
Query: 404 SVKEPLNIGG 413
V P +I G
Sbjct: 2066 QVHMPPSILG 2075
Score = 65.5 bits (158), Expect = 1e-10
Identities = 88/339 (25%), Positives = 140/339 (41%), Gaps = 39/339 (11%)
Query: 88 LHIESLSLGDEGIYTCQEI-LNVTQWFQVWLQVASGPYQIEVHIVATGTLPNGTLYAARG 146
L IE + L DEGIYTC L +V L+V P IE V L N
Sbjct: 1850 LQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPP-NIEPGPVNKAVLEN-------- 1900
Query: 147 SQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISPNLQ--GNYTCLAL 204
+ V C +S PPP V WF+ S G ++V+ L + L G+Y C+A
Sbjct: 1901 ASVTLECLASGVPPPDVS-WFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVAS 1959
Query: 205 NQLSKRHRKVTTELLVYYPPP-SAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWIEEPG 263
N ++ L V PP + P + ++LTC G P P +W+++ G
Sbjct: 1960 NVAGS--TELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGA-PSPTLMWLKD-G 2015
Query: 264 GVIVGKSKLGVEM--------LSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSLLS 315
+ G+++ L+ ++ SD ++ CV VG + + PS+L
Sbjct: 2016 NPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILG 2075
Query: 316 EPMKTCFTGG-NVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTI 374
E + +V L CQ S A PP + W ++ +P ++P ++ D L
Sbjct: 2076 EELNVSVVANESVALECQ-SHAMPPPVLSWWKD-GRP---LEPRPGVHLSAD---KALLQ 2127
Query: 375 HNCSQDLDEGYYICRADSPVGVRE----MEIWLSVKEPL 409
+ + D G+Y C A + G E + +W++ PL
Sbjct: 2128 VDRADVWDAGHYTCEALNQAGHSEKHYNLNVWVAPVFPL 2166
Score = 61.2 bits (147), Expect = 2e-09
Identities = 86/381 (22%), Positives = 146/381 (38%), Gaps = 43/381 (11%)
Query: 31 VVIGEVHENVTLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSLV-DATSLH 89
V++G+ E V N S N P N PR ++ D L
Sbjct: 2843 VILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQ 2902
Query: 90 IESLSLGDEGIYTC---QEILNVTQWFQVWLQVASGPYQIEVHIVATGTLPNGTLYAARG 146
+ + + D Y C + + + F + +QV +++ V A
Sbjct: 2903 VSTAEVADAASYMCVAENQAGSAEKLFTLRVQVPPRIAGLDLEQVT----------AILN 2952
Query: 147 SQVDFSCNSSSRPPPVVEWW--FQALNSSSESFGHNLTVNFFSLLLISPNL--QGNYTCL 202
S V C+ + P P V W+ QAL+ E F L +L L L G YTC
Sbjct: 2953 SSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVF---LLPGTHTLQLGRARLSDSGMYTCE 3009
Query: 203 ALNQLSKRHRKVTTELLV---YYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWI 259
ALN + + V +LV + P PQ + G + L+C D P+P W
Sbjct: 3010 ALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAV-LSCETD-ALPEPTVTWY 3067
Query: 260 EEPGGVIVGKSKLGVE-----MLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSLL 314
++ +++ + + + E+Q+SD + C S++ G E+ + + ++ P
Sbjct: 3068 KDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAG-EAVRTFTLTVQVPPTF 3126
Query: 315 SEPMKTCFT---GGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNST 371
P + G + LTC VSG P + WL++ + ++ S+ H + G
Sbjct: 3127 ENPKTETVSQVAGSPLVLTCDVSGV-PAPTVTWLKD----RMPVESSAVHGVVSRGGRLQ 3181
Query: 372 LTIHNCSQDLDEGYYICRADS 392
L + Q G Y C A++
Sbjct: 3182 L---SRLQPAQAGTYTCVAEN 3199
Score = 60.8 bits (146), Expect = 3e-09
Identities = 87/356 (24%), Positives = 143/356 (40%), Gaps = 50/356 (14%)
Query: 88 LHIESLSLGDEGIYTCQEILNVTQWFQ-VWLQVASGPY----QIEVHIVATGTLPNGTLY 142
L + S D G Y+C + V + Q V LQV P ++ V +VA
Sbjct: 2035 LTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVSVVAN--------- 2085
Query: 143 AARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISPNL--QGNYT 200
V C S + PPPV+ WW G +L+ + L + ++ G+YT
Sbjct: 2086 ----ESVALECQSHAMPPPVLSWWKDGRPLEPRP-GVHLSADKALLQVDRADVWDAGHYT 2140
Query: 201 CLALNQL--SKRHRKVTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLW 258
C ALNQ S++H + + +P + + + L CR G P P W
Sbjct: 2141 CEALNQAGHSEKHYNLNVWVAPVFPLRESHTLTVREGHPT-SLSCECR---GVPFPKISW 2196
Query: 259 IEE------PGGVIVGKSKLG-VEMLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGP 311
++ G + S +G + L ++QL+ + C S++VG S +++ P
Sbjct: 2197 RKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVG-NSSQDLQLEVHVP 2255
Query: 312 SLLSEPMK-----TCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQD 366
++ P + + G TL C +G PP + W R+ QP L Q
Sbjct: 2256 PQIAGPREPPTQVSVVQDGVATLECNATGK-PPPTVTWERD-------GQPVGAELGLQ- 2306
Query: 367 GQNSTLTIH-NCSQDLDEGYYICRADSPVGVREMEIWLSVKEPLNIGGIVGTIVSL 421
QN ++H +Q G Y C A++ G E + LSV P + G + + ++
Sbjct: 2307 LQNQGQSLHVERAQAAHTGRYSCVAENLAGRAERKFELSVLVPPELIGDLDPLTNI 2362
Score = 60.1 bits (144), Expect = 5e-09
Identities = 90/393 (22%), Positives = 137/393 (34%), Gaps = 47/393 (11%)
Query: 28 LEAVVIGEVHENVTLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSLVDATS 87
+ AVV+ V E L C +V WYR E + +SS +
Sbjct: 703 VNAVVLVAVGEEAVLVCEASGVPPPRVIWYRGGLEMILAPEGSSSGK------------- 749
Query: 88 LHIESLSLGDEGIYTCQEILNVTQWF-QVWLQVASGPYQIEVHIVATGTLPNGTLYAARG 146
L I + D G YTC+ + + ++ L V P E+ T L L A
Sbjct: 750 LRIPAAQERDAGTYTCRAVNELGDASAEIQLAVGHAPQLTELPRDVTVELGRSALLA--- 806
Query: 147 SQVDFSCNSSSRPPPVVEW---------WFQALNSSSESFGHNLTVNFFSLLLISPNLQG 197
C ++ RPPP V W S S + V FF ++P Q
Sbjct: 807 ------CRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFE--SVAPEDQA 858
Query: 198 NYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFL 257
Y C A N K + + + PP A + L C G P P+
Sbjct: 859 PYVCEARNVFGKVQAEARLIVTGHAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERH 918
Query: 258 WIEE----PGGVIVGKSKLGVEMLSESQLSDGKKFKCVTSHIVGPE-SGASCMVQIRGPS 312
W+++ P G G L + ++ CV ++ G + +VQ+
Sbjct: 919 WLKDGRPLPPGSRHSIRADGSLHLDRALQEHAGRYSCVATNTAGSQHRDVELVVQVPPRI 978
Query: 313 LLSEPMKTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTL 372
+ G +L C SG P I W + + + + ++++G TL
Sbjct: 979 HPTATHHITNEGVPASLPCVASGV-PAPTITWTK---ETNALTSRGPHYNVSKEG---TL 1031
Query: 373 TIHNCSQDLDEGYYICRADSPVGVREMEIWLSV 405
I S D G Y+C A + VG E+ LSV
Sbjct: 1032 LIAQPSAQ-DAGAYVCTATNTVGFSSQEMRLSV 1063
Score = 58.5 bits (140), Expect = 1e-08
Identities = 90/385 (23%), Positives = 151/385 (39%), Gaps = 75/385 (19%)
Query: 80 FSLVDATSLHIESLSLGDEGIYTC-----------QEILNVTQWFQVWLQVASGPYQIEV 128
+ L+ + SL + + +GD G Y C + +L V QV QV GP ++V
Sbjct: 1076 YGLLPSGSLRLAQVQVGDSGHYECTASNPAGSASHRYVLGV----QVPPQVQPGPRVLKV 1131
Query: 129 HIVATGTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSL 188
+ G +D +C + P P + W + + G +V+F +
Sbjct: 1132 LV---------------GEALDLNCVAEGNPEPQLSWSKDGV--VLQGRGPQGSVHFAA- 1173
Query: 189 LLISPNLQGNYTCLALNQLSKRHRKVTTELLVYYPP----PSAPQCWAQMASGSFMLQLT 244
I + G Y C A N +V EL V PP ++A + L
Sbjct: 1174 --IRTSDAGRYRCEASNSAGVDAWEV--ELRVLEPPHWGADETSGLLERVAGENASLPCP 1229
Query: 245 CRWDGGYPDPDFLWIEEPGGVIVGKSKLGVEMLSESQL-------SDGKKFKCVTSHIVG 297
R G P P W + P + + GV +L E L +D ++C ++ VG
Sbjct: 1230 AR---GTPKPQVTWRKGPSSEPL-HGQPGVAVLEEGSLFLASVSPADSGDYECQATNEVG 1285
Query: 298 PESGASCMVQIRGPSLLSEPMK---TCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVI 354
S + +V PS+ + K + G ++TL C +G +P +I+WL++ V
Sbjct: 1286 STSRRAKLVVYVPPSIREDGRKANVSGMAGQSLTLECDANG-FPVPEIVWLKDAQLVGVP 1344
Query: 355 I-----------QPSSRHLITQDGQNSTLTIH-NCSQDLDEGYYICRADSPVGVREMEIW 402
+ H + +GQ ++H Q+ D G Y CRA++ G + +
Sbjct: 1345 LGWAGYGWDLGWGQVGGHRLLDEGQ----SLHFPRIQEGDSGLYSCRAENQAGTAQRDFH 1400
Query: 403 LSVKEPLNIGGIVGTIVSLLLLGLA 427
L V P ++G + +LGLA
Sbjct: 1401 LLVLTP---PSVLGAGAAQEVLGLA 1422
Score = 57.4 bits (137), Expect = 3e-08
Identities = 69/296 (23%), Positives = 110/296 (37%), Gaps = 33/296 (11%)
Query: 124 YQIEVHIVATGTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTV 183
YQ+ VH+ T + V +C+S+ P P V W + G+ ++
Sbjct: 3849 YQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSP 3908
Query: 184 N-FFSLLLISPNLQGNYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSFMLQ 242
+ + P G YTC A N H+ V L V P P A +
Sbjct: 3909 SGALEIGQALPIHAGRYTCSARNSAGVAHKHVF--LTVQASPVVKPLPSVVRAVAEEEVL 3966
Query: 243 LTCRWDGGYPDPDFLWIEEPGGVIVGKSKL----GVEMLSESQLSDGKKFKCVTSHIVGP 298
L C G P P W +E V G S G ++ + D + C+ + G
Sbjct: 3967 LPCE-ASGIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGS 4025
Query: 299 ESGASCMVQIRGPSLLSEPMKTCFT--GGNVTLTCQVSGAYPPAKILWLRNLTQP----- 351
G + +V ++ P ++ + T G + L C+ G+ P I W ++ QP
Sbjct: 4026 AMGKTRLV-VQVPPVIENGLPDLSTTEGSHAFLPCKARGS-PEPNITWDKD-GQPVSGAE 4082
Query: 352 -EVIIQPSSRHLITQ-DGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSV 405
+ IQPS L+ +GQ D G Y C A++ VG + L++
Sbjct: 4083 GKFTIQPSGELLVKNLEGQ-------------DAGTYTCTAENAVGRARRRVHLTI 4125
Score = 57.4 bits (137), Expect = 3e-08
Identities = 67/274 (24%), Positives = 109/274 (39%), Gaps = 25/274 (9%)
Query: 143 AARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISPNLQGNYTCL 202
A +V C +S P P + W + LN ++ L + SP GNY C+
Sbjct: 3959 AVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCI 4018
Query: 203 ALNQLSKRHRKVTTELLVYYPPP---SAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWI 259
A N K T L+V PP P S +F L C+ G P+P+ W
Sbjct: 4019 AKNSAGSAMGK--TRLVVQVPPVIENGLPDLSTTEGSHAF---LPCKARGS-PEPNITWD 4072
Query: 260 EEPGGVIVGKSKLGVE-----MLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSLL 314
++ V + K ++ ++ + D + C + VG + + P
Sbjct: 4073 KDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLPVFT 4132
Query: 315 SEPM-KTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLT 373
+ P ++ G + L C G+ P +I W N +P + + QDG STL
Sbjct: 4133 TLPGDRSLRLGDRLWLRCAARGS-PTPRIGWTVN-------DRPVTEGVSEQDG-GSTLQ 4183
Query: 374 IHNCSQDLDEGYYICRADSPVGVREMEIWLSVKE 407
S++ D G Y+C A++ VG + ++ VKE
Sbjct: 4184 RAAVSRE-DSGTYVCWAENRVGRTQAVSFVHVKE 4216
Score = 57.0 bits (136), Expect = 4e-08
Identities = 90/409 (22%), Positives = 146/409 (35%), Gaps = 59/409 (14%)
Query: 26 VGLEAVVIGEVHENVTLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSL--- 82
+G E V +E+V L C + + ++W+++ RP EPR +
Sbjct: 2074 LGEELNVSVVANESVALECQSHAMPPPVLSWWKDG-------------RPLEPRPGVHLS 2120
Query: 83 VDATSLHIESLSLGDEGIYTCQEILNVTQWFQVWLQVASGPYQIEVHIVATGTLPNG-TL 141
D L ++ + D G YTC+ + + Y + V + L TL
Sbjct: 2121 ADKALLQVDRADVWDAGHYTCEALNQAGH--------SEKHYNLNVWVAPVFPLRESHTL 2172
Query: 142 YAARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISPNL---QGN 198
G SC P P + W E G LL + +G
Sbjct: 2173 TVREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGT 2232
Query: 199 YTCLALNQLSKRHRKVTTELLVYYPP----PSAPQCWAQMASGSFMLQLTCRWDGGYPDP 254
YTC N + + + E V+ PP P P + + L C G P P
Sbjct: 2233 YTCECSNVVGNSSQDLQLE--VHVPPQIAGPREPPTQVSVVQDG-VATLECNATGK-PPP 2288
Query: 255 DFLWIEEPGGVIVGKSKLGVEMLSE--------SQLSDGKKFKCVTSHIVGPESGASCMV 306
W E G VG ++LG+++ ++ +Q + ++ CV ++ G +
Sbjct: 2289 TVTW--ERDGQPVG-AELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGRAERKFELS 2345
Query: 307 QIRGPSLLSE--PMK--TCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHL 362
+ P L+ + P+ T +TL C+ G PPA I W R E + P
Sbjct: 2346 VLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPA-IRWFRG----EEPVSPGEDTY 2400
Query: 363 ITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEPLNI 411
+ G +T +Q+ D G Y C A + G + V P +I
Sbjct: 2401 LLAGGWMLKMTQ---TQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSI 2446
Score = 55.5 bits (132), Expect = 1e-07
Identities = 86/375 (22%), Positives = 136/375 (36%), Gaps = 43/375 (11%)
Query: 36 VHENVTLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSLVDATSLHIESLSL 95
++ +V+L C + +VTWY+++ +L E F L +L + L
Sbjct: 2951 LNSSVSLPCDVHAHPNPEVTWYKDSQ----------ALSLGEEVFLLPGTHTLQLGRARL 3000
Query: 96 GDEGIYTCQEILNVTQWFQVWLQVASGPYQIEVHIVATGTLPNGTLYAARGSQVDFSCNS 155
D G+YTC E LN Q +Q++ + P + G + SC +
Sbjct: 3001 SDSGMYTC-EALNAAGRDQKLVQLS---VLVPPAFRQAPRGPQDAVLVRVGDKAVLSCET 3056
Query: 156 SSRPPPVVEWW------FQALNSSSESFGHNLTVNFFSLLLISPNLQGNYTCLALNQLSK 209
+ P P V W+ A + + G L + + + +G Y+C N +
Sbjct: 3057 DALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQV-----SDKGLYSCKVSNVAGE 3111
Query: 210 RHRKVTTELLVYYPPP-SAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWIE-----EPG 263
R T L V PP P+ L LTC G P P W++ E
Sbjct: 3112 AVRTFT--LTVQVPPTFENPKTETVSQVAGSPLVLTCD-VSGVPAPTVTWLKDRMPVESS 3168
Query: 264 GVIVGKSKLGVEMLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSLLSEPMKT--- 320
V S+ G LS Q + + CV + + + P + S +
Sbjct: 3169 AVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHH 3228
Query: 321 CFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQD 380
G V L C+ G PP + WL++ + + P R + DG + L S
Sbjct: 3229 VLEGQEVRLDCEADG-QPPPDVAWLKDGSPLGQDMGPHLRFYL--DGGSLVLKGLRAS-- 3283
Query: 381 LDEGYYICRADSPVG 395
D G Y C A +P G
Sbjct: 3284 -DAGAYTCVAHNPAG 3297
Score = 55.5 bits (132), Expect = 1e-07
Identities = 94/389 (24%), Positives = 140/389 (35%), Gaps = 51/389 (13%)
Query: 28 LEAVVIGEVHENVTLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSLVDATS 87
L +VV E V L C R +TW + +S+ ++
Sbjct: 3953 LPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQ-----------VLPGGQ 4001
Query: 88 LHIESLSLGDEGIYTCQEILNVTQWFQVWLQVASGPYQIEVHI--VATGTLPNGTLYAAR 145
L I S D G Y C + A G ++ V + V LP+ L
Sbjct: 4002 LRIAHASPEDAGNYLCIAKNSAGS--------AMGKTRLVVQVPPVIENGLPD--LSTTE 4051
Query: 146 GSQVDFSCNSSSRPPPVVEWWF--QALNSSSESFGHNLTVNFFSLLLISPNLQGN----Y 199
GS C + P P + W Q ++ + F T+ LL+ NL+G Y
Sbjct: 4052 GSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKF----TIQPSGELLVK-NLEGQDAGTY 4106
Query: 200 TCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWI 259
TC A N + + R+V +LV + P + L+ R G P P W
Sbjct: 4107 TCTAENAVGRARRRVHLTILVLPVFTTLPGDRSLRLGDRLWLRCAAR---GSPTPRIGWT 4163
Query: 260 EEPGGVIVGKSKL-GVEMLSESQLS--DGKKFKCVTSHIVGPESGASCMVQIRGPSLLSE 316
V G S+ G L + +S D + C + VG S + P L E
Sbjct: 4164 VNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQGE 4223
Query: 317 PMKTCF--TGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTI 374
GG++ L C V G P I W+++ P + QN +LTI
Sbjct: 4224 AFSYLVEPVGGSIQLDCVVRGD-PVPDIHWIKDGL-------PLRGSHLRHQLQNGSLTI 4275
Query: 375 HNCSQDLDEGYYICRADSPVGVREMEIWL 403
H +D D G Y C A++ +GV + + L
Sbjct: 4276 HRTERD-DAGRYQCLAENEMGVAKKVVIL 4303
Score = 54.3 bits (129), Expect = 3e-07
Identities = 83/361 (22%), Positives = 127/361 (35%), Gaps = 62/361 (17%)
Query: 84 DATSLHIESLSLGDEGIYTCQEILNVTQWFQVWLQVASGP-------YQIEVHI-----V 131
D + L +ES G+Y+C VAS P Y +EV + V
Sbjct: 1648 DGSVLRLESPGEASSGLYSC---------------VASSPAGEAVLQYSVEVQVPPQLLV 1692
Query: 132 ATGTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLL- 190
A G G + G ++ C +S P P ++ W Q + E G + +L +
Sbjct: 1693 AEGL---GQVTTIVGQPLELPCQASGSPVPTIQ-WLQNGRPAEELAGVQVASQGTTLHID 1748
Query: 191 -ISPNLQGNYTCLALNQLSKRHRKVTTELLVYYPP-----PSAPQCWAQMASGSFMLQL- 243
+ + G + C A N+ +V + + P P W SF
Sbjct: 1749 HVELDHSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLEVPIGQYHWGXEHHSSFPAACD 1808
Query: 244 --TCRWDGGYPDPDF---------LWIEEPGGVIVGKSKLGVEMLSESQLSDGKKFKCVT 292
R G +P P LW EP G+ V S + + L D + C
Sbjct: 1809 PPVHRGWGAHPKPPLVEGWCSPGSLW-GEPTGIPVAYSLPPPLQIEKVDLRDEGIYTCAA 1867
Query: 293 SHIVGPESGASCMVQIRGPSLLSEPM-KTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQP 351
+++ G + + P++ P+ K +VTL C SG PP + W +
Sbjct: 1868 TNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLECLASGV-PPPDVSWFKG---- 1922
Query: 352 EVIIQPSSRHL-ITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEPLN 410
QP S + +T L I +Q D G Y C A + G E+ L V P
Sbjct: 1923 ---HQPVSSWMGVTVSVDGRVLRIEQ-AQLSDAGSYRCVASNVAGSTELRYGLRVNVPPR 1978
Query: 411 I 411
I
Sbjct: 1979 I 1979
Score = 53.9 bits (128), Expect = 4e-07
Identities = 74/337 (21%), Positives = 126/337 (37%), Gaps = 32/337 (9%)
Query: 77 EPRFSLVDATSLHIESLSLGDEGIYTCQEILNV-TQWFQVWLQVASGPYQIEVHIVATGT 135
E F +S I S +EG Y C + T + + V P Q+
Sbjct: 470 ERHFQESGNSSWEILRASKAEEGTYECTAVSRAGTGRAKAQIVVTDPPPQL--------- 520
Query: 136 LPNGTLYAARGSQVDFSCNSSSRPPPVVEWW--FQALNSSSESFGHNLTVNFFSLLLISP 193
+P + + G SC P + W ++ L +S+ ++ + I P
Sbjct: 521 VPAPNVTVSPGETAVLSCRVLGEAPYNLTWVRDWRVLPASTGRVAQLADLSL-EISGIIP 579
Query: 194 NLQGNYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPD 253
G Y C+A N + + + LLV P + +Q S ++++C GYP
Sbjct: 580 TDGGRYQCVASN--ANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCS-ASGYPT 636
Query: 254 PDFLWIEEPGGVI----VGKSKLGVEMLSESQLSDGKKFKCVTSHIVGPESGASCMVQIR 309
P W E + + G ++ D + C ++ VG + +
Sbjct: 637 PHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTLYYTD 696
Query: 310 GPSLLS-EPMKTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQ 368
PS+ + + G L C+ SG PP +++W R E+I+ P +G
Sbjct: 697 PPSVSAVNAVVLVAVGEEAVLVCEASGV-PPPRVIWYRGGL--EMILAP--------EGS 745
Query: 369 NSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSV 405
+S +Q+ D G Y CRA + +G EI L+V
Sbjct: 746 SSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAV 782
Score = 52.4 bits (124), Expect = 1e-06
Identities = 89/377 (23%), Positives = 147/377 (38%), Gaps = 56/377 (14%)
Query: 41 TLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSLVD-ATSLHIESLSLGDEG 99
TL C VTW R+ +PV AE L + SLH+E G
Sbjct: 2277 TLECNATGKPPPTVTWERDG-QPV----------GAELGLQLQNQGQSLHVERAQAAHTG 2325
Query: 100 IYTC-QEILNVTQWFQVWLQVASGPYQIEVHIVATGTL-PNGTLYAARGSQVDFSCNSSS 157
Y+C E L + L V P I G L P + AA S + C +
Sbjct: 2326 RYSCVAENLAGRAERKFELSVLVPPELI-------GDLDPLTNITAALHSPLTLLCEAMG 2378
Query: 158 RPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISPNLQ--GNYTCLALNQLSKRHRKVT 215
PPP + WF+ S L + L + Q G Y+CLA N+ + R +
Sbjct: 2379 IPPPAIR-WFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFS 2437
Query: 216 TELLVYYPPPSAPQCWAQM------ASGSFMLQLTCRWDGGYPDPDFLWIEEPGGVIVGK 269
E+LV PP + ++ + M +T G+P P W ++ + G
Sbjct: 2438 VEVLV--PPSIENEDLEEVIKVLDGQTAHLMCNVT-----GHPQPKLTWFKDGRPLARGD 2490
Query: 270 ----SKLGVEM-LSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSLL------SEPM 318
S GV + + ++ LS + C+ ++ VG ++ + + P++L ++
Sbjct: 2491 AHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEE 2550
Query: 319 KTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCS 378
T ++L C+ A+P I W+++ E +SR++ G + L I N
Sbjct: 2551 VTVTVNNPISLICEAL-AFPSPNITWMKDGAPFE-----ASRNIQLLPGTHG-LQILNAQ 2603
Query: 379 QDLDEGYYICRADSPVG 395
++ D G Y C + +G
Sbjct: 2604 KE-DAGQYTCVVTNELG 2619
Score = 51.6 bits (122), Expect = 2e-06
Identities = 55/241 (22%), Positives = 101/241 (41%), Gaps = 20/241 (8%)
Query: 186 FSLLLISPNLQGNYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSFMLQLTC 245
+ +L S +G Y C A+++ K +++V PPP S L+C
Sbjct: 481 WEILRASKAEEGTYECTAVSRAGTGRAKA--QIVVTDPPPQLVPAPNVTVSPGETAVLSC 538
Query: 246 RWDGGYPDPDFLWIEE------PGGVIVGKSKLGVEMLSESQLSDGKKFKCVTSHIVGPE 299
R G P + W+ + G + + L +E +S +DG +++CV S+ G
Sbjct: 539 RVLGEAPY-NLTWVRDWRVLPASTGRVAQLADLSLE-ISGIIPTDGGRYQCVASNANGVT 596
Query: 300 SGASCMVQIRGPSLLSEPMKTCFTGG-NVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPS 358
+ ++ P + F+ G V ++C SG YP I W R + + + + S
Sbjct: 597 RASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSASG-YPTPHISWSR---ESQALQEDS 652
Query: 359 SRHLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEPLNIGGIVGTI 418
H+ Q TL I + + D G Y C+A + VG + + L +P ++ + +
Sbjct: 653 RIHVDAQ----GTLIIQGVAPE-DAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVV 707
Query: 419 V 419
+
Sbjct: 708 L 708
Score = 49.3 bits (116), Expect = 9e-06
Identities = 83/354 (23%), Positives = 126/354 (35%), Gaps = 62/354 (17%)
Query: 83 VDATSLHIESLSLGDEGIYTCQEILNVTQWFQVWLQVASGP-------YQIEVHIVAT-- 133
+D SL ++ L D G YTC VA P + + V + T
Sbjct: 3270 LDGGSLVLKGLRASDAGAYTC---------------VAHNPAGEDARLHTVNVLVPPTIK 3314
Query: 134 -GTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWWFQAL------NSSSESFGHNLTVNFF 186
G +GTL + G V C PP V W L + GH L ++
Sbjct: 3315 QGADGSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKV 3374
Query: 187 SLLLISPNLQGNYTCLALNQLSKRHRKVTTELLVYYPPPSAP---QCWAQMASGSFMLQL 243
L G +TC+A + R T ++ V PP P Q + GS +++L
Sbjct: 3375 QLADA-----GIFTCVAASPAGVADRNFTLQVQV--PPVLEPVEFQNDVVVVRGS-LVEL 3426
Query: 244 TCRWDGGYPDPDFLWIEEPGGVIVGKSKLGVEMLSESQ-LSDGKKFKCVTSHIVGPESGA 302
C G P P W+++ ++ + G + E+ D + CV G
Sbjct: 3427 PCE-ARGVPLPLVSWMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRH 3485
Query: 303 SCMVQIRGPSL--LSEPMKTCFT-GGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSS 359
+ + P + +P + T G + L C G P I W ++
Sbjct: 3486 FQLTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGT-PQPNITWHKD------------ 3532
Query: 360 RHLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEPLNIGG 413
+T+ NS T + D G Y C A+SP G E + V+ P NI G
Sbjct: 3533 GQALTRLENNSRAT--RVLRVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVG 3584
Score = 48.9 bits (115), Expect = 1e-05
Identities = 98/489 (20%), Positives = 176/489 (35%), Gaps = 86/489 (17%)
Query: 2 AAGGSAPEPRVLVCLGALLAGWVAVGLEAVVIGEVHENVTLHCGNISGLRGQVTWYRNNS 61
A G ++ V L + G + V V+ ++L C ++ +TW ++ +
Sbjct: 2521 AVGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMKDGA 2580
Query: 62 EPVFLLSSNSSLRPAEPRFSLVDATSLHIESLSLGDEGIYTC---QEILNVTQWFQVWL- 117
F S N L P +++A D G YTC E+ + + V +
Sbjct: 2581 P--FEASRNIQLLPGTHGLQILNAQK--------EDAGQYTCVVTNELGEAVKNYHVEVL 2630
Query: 118 ---QVASGPYQIEVHIVATGTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWWFQALNSSS 174
++ EV + T N TL C S + PPP + W+ +
Sbjct: 2631 IPPSISKDDPLGEVGVKEVKTKVNSTL--------TLECESWAVPPPTIRWYKDGQPVTP 2682
Query: 175 ESFGHNLTVNFFSLLLISPNL---QGNYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCW 231
S + LL I P G Y C+A N + + +L+ PP +
Sbjct: 2683 SS--RLQVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDF--NVLIQVPP-----MF 2733
Query: 232 AQMASGSFMLQLTCRWD---GG---------------------YPDPDFLWIEEPG---- 263
++ S ++ R + GG P PD W E
Sbjct: 2734 QKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWYREDQPLSA 2793
Query: 264 ----GVIVGKSKLGVEMLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSLLSEPMK 319
V+ G L + ++ + + ++ C S+ VG + ++ + P +L + +
Sbjct: 2794 GDEVSVLQGGRVLQIPLV---RAENAGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEE 2850
Query: 320 -----TCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTI 374
T V+L C G P I WL+N + PS R + +DGQ +
Sbjct: 2851 LVEEVTVNASSTVSLQCPALG-NPVPTISWLQN----GLPFSPSPRLQVLEDGQVLQV-- 2903
Query: 375 HNCSQDLDEGYYICRADSPVGVREMEIWLSVKEPLNIGGI-VGTIVSLLLLGLAIISGLL 433
+ ++ D Y+C A++ G E L V+ P I G+ + + ++L +++ +
Sbjct: 2904 -STAEVADAASYMCVAENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVH 2962
Query: 434 LHYSPVFCW 442
H +P W
Sbjct: 2963 AHPNPEVTW 2971
Score = 45.4 bits (106), Expect = 1e-04
Identities = 89/407 (21%), Positives = 153/407 (37%), Gaps = 63/407 (15%)
Query: 35 EVHENVTLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSLVDATSLHIESLS 94
+V+ +TL C + + + WY++ +PV P+ L + L I+
Sbjct: 2652 KVNSTLTLECESWAVPPPTIRWYKDG-QPV---------TPSSRLQVLGEGRLLQIQPTQ 2701
Query: 95 LGDEGIYTCQEILNVT----QWFQVWLQVAS-----GPYQIEVHIVATGTLPNGTLYAAR 145
+ D G Y C NV Q F V +QV G + I++ G + R
Sbjct: 2702 VSDSGRYLCVAT-NVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYR 2760
Query: 146 ----GSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTV----NFFSLLLISPNLQG 197
+ C++++ PPP + W+ + S G ++V + L+ G
Sbjct: 2761 EIVENNPAYLYCDTNAIPPPDLTWYRE---DQPLSAGDEVSVLQGGRVLQIPLVRAENAG 2817
Query: 198 NYTCLALNQLSKRHRKVTTELLVYYPP----PSAPQCWAQMASGSFMLQLTCRWDGGYPD 253
Y+C A N++ + + ELLV PP + + S + L C G P
Sbjct: 2818 RYSCKASNEVGEDW--LHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALGN-PV 2874
Query: 254 PDFLWIE-----EPGGVIVGKSKLGVEMLSESQLSDGKKFKCVTSHIVG-PESGASCMVQ 307
P W++ P + V +S ++++D + CV + G E + VQ
Sbjct: 2875 PTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGSAEKLFTLRVQ 2934
Query: 308 IRGPSL--LSEPMKTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQ----PEVIIQPSSRH 361
+ P + L T +V+L C V A+P ++ W ++ EV + P +
Sbjct: 2935 V-PPRIAGLDLEQVTAILNSSVSLPCDVH-AHPNPEVTWYKDSQALSLGEEVFLLPGTHT 2992
Query: 362 LITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEP 408
L + S D G Y C A + G + + LSV P
Sbjct: 2993 LQLGRARLS-----------DSGMYTCEALNAAGRDQKLVQLSVLVP 3028
Score = 44.7 bits (104), Expect = 2e-04
Identities = 82/349 (23%), Positives = 127/349 (36%), Gaps = 37/349 (10%)
Query: 73 LRPAEPRFSLVDATSLHIESLSLGDEGIYTCQEILNVTQWFQVW-LQVASGPYQIEVHIV 131
L P PRF ++ SL I+ + D G Y C + Q L+V P
Sbjct: 3713 LDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEPP-------- 3764
Query: 132 ATGTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWW--FQALNSSSESFGHNLTVNFFSLL 189
A P+ A + C +S P P+V WW Q L+ + + L + +LL
Sbjct: 3765 AIAPSPSNLTLTAHTPAL-LPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPS-NALL 3822
Query: 190 LISPNLQ--GNYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRW 247
L +P Q + C+ N++ + HR ++ V+ PP A + + LTC
Sbjct: 3823 LTAPGPQDSAQFECVVSNEVGEAHR--LYQVTVHVPPTIADDQTDFTVTMMAPVVLTCH- 3879
Query: 248 DGGYPDPDFLWIEEPGGVIVGKSKLGVEMLSESQLSDGK-------KFKCVTSHIVGPES 300
G P P W G +G G + L G+ ++ C + G
Sbjct: 3880 STGIPAPTVSW--SKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAGVAH 3937
Query: 301 GASCMVQIRGPSLLSEP-MKTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSS 359
+ P + P + V L C+ SG P I W Q E + +
Sbjct: 3938 KHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASG-IPRPTITW-----QKEGLNVATG 3991
Query: 360 RHLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEP 408
+ TQ L I + S + D G Y+C A + G + L V+ P
Sbjct: 3992 --VSTQVLPGGQLRIAHASPE-DAGNYLCIAKNSAGSAMGKTRLVVQVP 4037
Score = 44.3 bits (103), Expect = 3e-04
Identities = 68/290 (23%), Positives = 115/290 (39%), Gaps = 41/290 (14%)
Query: 142 YAARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISPNLQ----G 197
+ G +V C + +PPP V W + + + G +L L+ L+ G
Sbjct: 3228 HVLEGQEVRLDCEADGQPPPDVA-WLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAG 3286
Query: 198 NYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSF------MLQLTCRWDGGY 251
YTC+A N + R T +LV PP+ Q SG+ ++ + C G
Sbjct: 3287 AYTCVAHNPAGEDARLHTVNVLV---PPTIKQ--GADGSGTLVSRPGELVTMVCPVRGS- 3340
Query: 252 PDPDFLWIEEPGGVIVGKSKL-----GVEMLSESQLSDGKKFKCVTSHIVGPESGASCMV 306
P W+++ + + + L +S+ QL+D F CV + G + + +
Sbjct: 3341 PPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAG-VADRNFTL 3399
Query: 307 QIRGPSLLSEPMK-----TCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRH 361
Q++ P +L EP++ G V L C+ G P + W+++ E ++ S
Sbjct: 3400 QVQVPPVL-EPVEFQNDVVVVRGSLVELPCEARGV-PLPLVSWMKD---GEPLLSQS--- 3451
Query: 362 LITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEPLNI 411
+ G + L D G Y C A S G L+V EP +I
Sbjct: 3452 --LEQGPSLQLEAVGAG---DSGTYSCVAVSEAGEARRHFQLTVMEPPHI 3496
Score = 43.9 bits (102), Expect = 4e-04
Identities = 86/361 (23%), Positives = 135/361 (37%), Gaps = 59/361 (16%)
Query: 71 SSLRPAEPRFS--LVDATSLHIESLSLGDEGIYTC---QEILNVTQWFQVWLQVASGPYQ 125
S ++ EP S L SL +E++ GD G Y+C E + FQ L V P
Sbjct: 3439 SWMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQ--LTVMEPP-- 3494
Query: 126 IEVHIVATGTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWW--FQALNSSSESFGHNLTV 183
HI +G L G+ ++ C++ P P + W QAL L
Sbjct: 3495 ---HIEDSGQPTE--LSLTPGAPMELLCDAQGTPQPNITWHKDGQALT--------RLEN 3541
Query: 184 NFFSLLLISPNLQGNYTCLALNQLSKRHRKVTTELLVYYPP----PSAPQCWAQMASGSF 239
N + ++ G YTCLA + + + + V PP P P+ +A G
Sbjct: 3542 NSRATRVLRVRDAGLYTCLAESPAGAIEK--SFRVRVQAPPNIVGPRGPRFVVGLAPGQL 3599
Query: 240 MLQLTCRWDGGYPDPDFLWIEEPGGVIVGKSK----------LGVEMLSESQLSDGKKFK 289
+L+ + + P P W + G+++ + L ++ LS + D +
Sbjct: 3600 VLECSVEAE---PAPKITWHRD--GIVLQEDAHTQFPERGRFLQLQALSTADSGD---YS 3651
Query: 290 CVTSHIVGPESGASCMVQIRGPSLLS-EPMKTCFTGGNVTLTCQVSGAYPPAKILWLRNL 348
C + G S A + P++ S P L CQ G P + W ++
Sbjct: 3652 CTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGV-PAPLVSWRKD- 3709
Query: 349 TQPEVIIQP-SSRHLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKE 407
V + P S R I +G +L I D G+Y+C A + G L V E
Sbjct: 3710 ---RVPLDPRSPRFEILPEG---SLRIQPVLAQ-DAGHYLCLASNSAGSDRQGRDLRVLE 3762
Query: 408 P 408
P
Sbjct: 3763 P 3763
Score = 39.7 bits (91), Expect = 0.007
Identities = 81/353 (22%), Positives = 120/353 (33%), Gaps = 69/353 (19%)
Query: 97 DEGIYTCQEILNVTQWFQVWLQVASGPYQIEVHIVATGTLPNGTLY---AARGSQVDFSC 153
D G+YTC+ V A +++V++ T G Y A G V C
Sbjct: 1567 DAGVYTCKASNAVG--------AAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALEC 1618
Query: 154 NSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISPN--LQGNYTCLALNQLSKRH 211
+ P P + W + L +ES L + L L SP G Y+C+A + +
Sbjct: 1619 VARGHPSPTLSWHHEGL-PVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAV 1677
Query: 212 RKVTTELLVYYPPPSAPQCWAQMASGSFM------LQLTCRWDGGYPDPDFLWI------ 259
+ + E+ V PQ G L+L C+ G P P W+
Sbjct: 1678 LQYSVEVQV------PPQLLVAEGLGQVTTIVGQPLELPCQASGS-PVPTIQWLQNGRPA 1730
Query: 260 EEPGGVIVGKSKLGVEMLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRG---PSLLSE 316
EE GV V + + +L F C ++ G +GA V + G P +L
Sbjct: 1731 EELAGVQVASQGTTLH-IDHVELDHSGLFACQATNEAG-TAGAEVEVSVHGEWAPGVLEV 1788
Query: 317 PMKTCFTG----GNVTLTCQVS-----GAYPPAKI---------LWLRNLTQPEVIIQPS 358
P+ G + C GA+P + LW P P
Sbjct: 1789 PIGQYHWGXEHHSSFPAACDPPVHRGWGAHPKPPLVEGWCSPGSLWGEPTGIPVAYSLPP 1848
Query: 359 SRHLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEPLNI 411
+ D + DEG Y C A + G + E+ L V P NI
Sbjct: 1849 PLQIEKVDLR-------------DEGIYTCAATNLAGESKREVALKVLVPPNI 1888
Score = 35.0 bits (79), Expect = 0.17
Identities = 80/363 (22%), Positives = 134/363 (36%), Gaps = 63/363 (17%)
Query: 197 GNYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASG--------SFMLQLTCRWD 248
G YTC+ N+L + + E+L+ PPS + G + L L C
Sbjct: 2608 GQYTCVVTNELGEAVKNYHVEVLI---PPSISKDDPLGEVGVKEVKTKVNSTLTLECE-S 2663
Query: 249 GGYPDPDFLWIEEPGGVIVGKSKLGV------EMLSESQLSDGKKFKCVTSHIVGPESGA 302
P P W ++ G + S+L V + +Q+SD ++ CV +++ G E
Sbjct: 2664 WAVPPPTIRWYKD-GQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVATNVAG-EDDQ 2721
Query: 303 SCMVQIRGPSLLSE--PMKTCF--------TGGNVT------------LTCQVSGAYPPA 340
V I+ P + + F G VT L C + A PP
Sbjct: 2722 DFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYCD-TNAIPPP 2780
Query: 341 KILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREME 400
+ W R QP + + Q G+ + + + G Y C+A + VG +
Sbjct: 2781 DLTWYRE-DQP---LSAGDEVSVLQGGRVLQIPLVRAE---NAGRYSCKASNEVGEDWLH 2833
Query: 401 IWLSVKEPLNIGGIVGTIVSLLLLGLAIISGL----LLHYSPVFCW-----KVGNTSRGQ 451
L V P I G +V + + + L L + P W + R Q
Sbjct: 2834 YELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQ 2893
Query: 452 NMDDVMVLVDSEEEEEEEEE---EEEDAAVGEQEGAREREELPKEIPKQDHIHRVTALVN 508
++D VL S E + E+ A ++ R ++P I D + +VTA++N
Sbjct: 2894 VLEDGQVLQVSTAEVADAASYMCVAENQAGSAEKLFTLRVQVPPRIAGLD-LEQVTAILN 2952
Query: 509 GNI 511
++
Sbjct: 2953 SSV 2955
Score = 31.2 bits (69), Expect = 2.5
Identities = 37/170 (21%), Positives = 62/170 (36%), Gaps = 10/170 (5%)
Query: 146 GSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISPNLQGNYTCLALN 205
G + C P P + W L H L ++ + G Y CLA N
Sbjct: 4233 GGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAEN 4292
Query: 206 QLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWIEEPGGV 265
++ +KV +L P + SG + L C+ G P P W+ + G
Sbjct: 4293 EMGVA-KKVVILVLQSAPVFQVEPQDMTVRSGD-DVALRCQ-ATGEPTPTIEWL-QAGQP 4348
Query: 266 IVGKSKL-----GVEMLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRG 310
+ +L G L + D + CV +++G + + +V +RG
Sbjct: 4349 LRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNLLGSATARAFLV-VRG 4397
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 67.4 bits (163), Expect = 3e-11
Identities = 95/370 (25%), Positives = 147/370 (39%), Gaps = 52/370 (14%)
Query: 74 RPAEPRFSLVDA---TSLHIESLSLGDEGIYTCQEILNV-TQWFQVWLQV----ASGPYQ 125
RPAE + A T+LHI+ + L G++ CQ T +V + V A G +
Sbjct: 537 RPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLE 596
Query: 126 IEVHIVATGTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNF 185
+ + G + + AA V + + PP+VE W + E G + +
Sbjct: 597 VPIGQYHWGXEHHSSFPAACDPPVHRGWGAHPK-PPLVEGWCSPGSLWGEPTGIPVAYSL 655
Query: 186 ---FSLLLISPNLQGNYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSFMLQ 242
+ + +G YTC A N + R+V ++LV PP P + + +
Sbjct: 656 PPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLV--PPNIEPGPVNKAVLENASVT 713
Query: 243 LTCRWDGGYPDPDFLWIEEPGGVIVGKSKLGVEM--------LSESQLSDGKKFKCVTSH 294
L C G P PD W + V S +GV + + ++QLSD ++CV S+
Sbjct: 714 LEC-LASGVPPPDVSWFKGHQPV---SSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASN 769
Query: 295 IVGPES---GASCMVQIR--------GPSLLSEPMKTCFTGGNVTLTCQVSGAYPPAKIL 343
+ G G V R GP L++ P V LTC +GA P ++
Sbjct: 770 VAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTP---------VRLTCNATGA-PSPTLM 819
Query: 344 WLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWL 403
WL++ P + + G+ TL S D G Y C A S VG ++ L
Sbjct: 820 WLKDGNPVSPAGTPGLQ--VFPGGRVLTLASARAS---DSGRYSCVAVSAVGEDRQDVVL 874
Query: 404 SVKEPLNIGG 413
V P +I G
Sbjct: 875 QVHMPPSILG 884
Score = 65.5 bits (158), Expect = 1e-10
Identities = 88/339 (25%), Positives = 140/339 (41%), Gaps = 39/339 (11%)
Query: 88 LHIESLSLGDEGIYTCQEI-LNVTQWFQVWLQVASGPYQIEVHIVATGTLPNGTLYAARG 146
L IE + L DEGIYTC L +V L+V P IE V L N
Sbjct: 659 LQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPP-NIEPGPVNKAVLEN-------- 709
Query: 147 SQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISPNLQ--GNYTCLAL 204
+ V C +S PPP V WF+ S G ++V+ L + L G+Y C+A
Sbjct: 710 ASVTLECLASGVPPPDVS-WFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVAS 768
Query: 205 NQLSKRHRKVTTELLVYYPPP-SAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWIEEPG 263
N ++ L V PP + P + ++LTC G P P +W+++ G
Sbjct: 769 NVAGS--TELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGA-PSPTLMWLKD-G 824
Query: 264 GVIVGKSKLGVEM--------LSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSLLS 315
+ G+++ L+ ++ SD ++ CV VG + + PS+L
Sbjct: 825 NPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILG 884
Query: 316 EPMKTCFTGG-NVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTI 374
E + +V L CQ S A PP + W ++ +P ++P ++ D L
Sbjct: 885 EELNVSVVANESVALECQ-SHAMPPPVLSWWKD-GRP---LEPRPGVHLSAD---KALLQ 936
Query: 375 HNCSQDLDEGYYICRADSPVGVRE----MEIWLSVKEPL 409
+ + D G+Y C A + G E + +W++ PL
Sbjct: 937 VDRADVWDAGHYTCEALNQAGRSEKHYNLNVWVAPVFPL 975
Score = 63.9 bits (154), Expect = 4e-10
Identities = 101/405 (24%), Positives = 151/405 (37%), Gaps = 60/405 (14%)
Query: 24 VAVGLEAVVIGEVHENVTLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSLV 83
+ G V+G +V L C QV W ++ +PV P P +
Sbjct: 219 LGAGAAQEVLGLAGADVELQCWTSGVPTPQVEWTKDR-QPVL---------PGGPHLQVQ 268
Query: 84 -DATSLHIESLSLGDEGIYTCQEILNVTQWFQVWLQVASGPYQIEVHIVAT--GTLPNGT 140
D L I +GDEG Y C Q + +Q+ VH T G+ G
Sbjct: 269 EDGQVLRITGSHVGDEGRYQCVAFSPAGQ--------QARDFQLRVHAPPTIWGSNETGE 320
Query: 141 LYAARGSQVDFSCNSSSRPPPVVEWWFQ-ALNSSSESFGHNLTVNFFSLLLISPNLQGNY 199
+ V C + P P + W+ AL +S + L + G Y
Sbjct: 321 VAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVY 380
Query: 200 TCLALNQLSKRHRKVTTELLVYYPPP-----SAPQCWAQMASGSFMLQLTCRWDGGYPDP 254
TC A N + + T L VY PP P +A L+ R G+P P
Sbjct: 381 TCKASNAVGAAEK--ATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVAR---GHPSP 435
Query: 255 DFLWIEEPGGVIVGKSKLG--------VEMLSESQLSDGKKFKCVTSHIVGPESGASCMV 306
W E G+ V +S + + S + S G + CV S G E+ V
Sbjct: 436 TLSWHHE--GLPVAESNESRLETDGSVLRLESPGEASSG-LYSCVASSPAG-EAVLQYSV 491
Query: 307 QIRGPS--LLSEPM--KTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVI--IQPSSR 360
+++ P L++E + T G + L CQ SG+ P I WL+N E + +Q +S
Sbjct: 492 EVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGS-PVPTIQWLQNGRPAEELAGVQVAS- 549
Query: 361 HLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSV 405
Q +TL I + D G + C+A + G E+ +SV
Sbjct: 550 -------QGTTLHIDHVELD-HSGLFACQATNEAGTAGAEVEVSV 586
Score = 61.2 bits (147), Expect = 2e-09
Identities = 86/381 (22%), Positives = 146/381 (38%), Gaps = 43/381 (11%)
Query: 31 VVIGEVHENVTLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSLV-DATSLH 89
V++G+ E V N S N P N PR ++ D L
Sbjct: 1652 VILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQ 1711
Query: 90 IESLSLGDEGIYTC---QEILNVTQWFQVWLQVASGPYQIEVHIVATGTLPNGTLYAARG 146
+ + + D Y C + + + F + +QV +++ V A
Sbjct: 1712 VSTAEVADAASYMCVAENQAGSAEKLFTLRVQVPPRIAGLDLEQVT----------AILN 1761
Query: 147 SQVDFSCNSSSRPPPVVEWW--FQALNSSSESFGHNLTVNFFSLLLISPNL--QGNYTCL 202
S V C+ + P P V W+ QAL+ E F L +L L L G YTC
Sbjct: 1762 SSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVF---LLPGTHTLQLGRARLSDSGMYTCE 1818
Query: 203 ALNQLSKRHRKVTTELLV---YYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWI 259
ALN + + V +LV + P PQ + G + L+C D P+P W
Sbjct: 1819 ALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAV-LSCETD-ALPEPTVTWY 1876
Query: 260 EEPGGVIVGKSKLGVE-----MLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSLL 314
++ +++ + + + E+Q+SD + C S++ G E+ + + ++ P
Sbjct: 1877 KDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAG-EAVRTFTLTVQVPPTF 1935
Query: 315 SEPMKTCFT---GGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNST 371
P + G + LTC VSG P + WL++ + ++ S+ H + G
Sbjct: 1936 ENPKTETVSQVAGSPLVLTCDVSGV-PAPTVTWLKD----RMPVESSAVHGVVSRGGRLQ 1990
Query: 372 LTIHNCSQDLDEGYYICRADS 392
L + Q G Y C A++
Sbjct: 1991 L---SRLQPAQAGTYTCVAEN 2008
Score = 60.8 bits (146), Expect = 3e-09
Identities = 87/356 (24%), Positives = 143/356 (40%), Gaps = 50/356 (14%)
Query: 88 LHIESLSLGDEGIYTCQEILNVTQWFQ-VWLQVASGPY----QIEVHIVATGTLPNGTLY 142
L + S D G Y+C + V + Q V LQV P ++ V +VA
Sbjct: 844 LTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVSVVAN--------- 894
Query: 143 AARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISPNL--QGNYT 200
V C S + PPPV+ WW G +L+ + L + ++ G+YT
Sbjct: 895 ----ESVALECQSHAMPPPVLSWWKDGRPLEPRP-GVHLSADKALLQVDRADVWDAGHYT 949
Query: 201 CLALNQL--SKRHRKVTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLW 258
C ALNQ S++H + + +P + + + L CR G P P W
Sbjct: 950 CEALNQAGRSEKHYNLNVWVAPVFPLRESHTLTVREGHPT-SLSCECR---GVPFPKISW 1005
Query: 259 IEE------PGGVIVGKSKLG-VEMLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGP 311
++ G + S +G + L ++QL+ + C S++VG S +++ P
Sbjct: 1006 RKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVG-NSSQDLQLEVHVP 1064
Query: 312 SLLSEPMK-----TCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQD 366
++ P + + G TL C +G PP + W R+ QP L Q
Sbjct: 1065 PQIAGPREPPTQVSVVQDGVATLECNATGK-PPPTVTWERD-------GQPVGAELGLQ- 1115
Query: 367 GQNSTLTIH-NCSQDLDEGYYICRADSPVGVREMEIWLSVKEPLNIGGIVGTIVSL 421
QN ++H +Q G Y C A++ G E + LSV P + G + + ++
Sbjct: 1116 LQNQGQSLHVERAQAAHTGRYSCVAENLAGRAERKFELSVLVPPELIGDLDPLTNI 1171
Score = 58.9 bits (141), Expect = 1e-08
Identities = 78/304 (25%), Positives = 112/304 (36%), Gaps = 56/304 (18%)
Query: 153 CNSSSRPPPVVEWWFQALNSSSESFGHN-----LTVNFFSLLLISPNLQGNYTCLALNQL 207
C + P P V W SSE L L +SP G+Y C A N++
Sbjct: 24 CGTHGTPKPQVTW---RKGPSSEPLHGQPGVAVLEEGSLFLASVSPADSGDYECQATNEV 80
Query: 208 SKRHRKVTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRWD-GGYPDPDFLWIEEPG--G 264
R+ +L+VY PP SG LT D G+P P+ +W+++ G
Sbjct: 81 GSTSRR--AKLVVYVPPSIREDGRKANVSGMAGQSLTLECDANGFPVPEIVWLKDAQLVG 138
Query: 265 VIVGKSKLGVE----------MLSESQLSDGKKFKCVTSHIVGPESGASCMV-------- 306
V +G + G + +L E Q + + S G ++G S
Sbjct: 139 VPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFPRIQPGRSGRRGAQAGGSAQTKAPWXAGL 198
Query: 307 ----QIRGPSLLSEPMKTC------------FTGGNVTLTCQVSGAYPPAKILWLRNLTQ 350
Q P S P G +V L C SG P ++ W ++ Q
Sbjct: 199 AGFEQFPTPHAFSPPAPPSVLGAGAAQEVLGLAGADVELQCWTSGV-PTPQVEWTKD-RQ 256
Query: 351 PEVIIQPSSRHL-ITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEPL 409
P + P HL + +DGQ +T + DEG Y C A SP G + + L V P
Sbjct: 257 P---VLPGGPHLQVQEDGQVLRITGSHVG---DEGRYQCVAFSPAGQQARDFQLRVHAPP 310
Query: 410 NIGG 413
I G
Sbjct: 311 TIWG 314
Score = 57.4 bits (137), Expect = 3e-08
Identities = 90/409 (22%), Positives = 147/409 (35%), Gaps = 59/409 (14%)
Query: 26 VGLEAVVIGEVHENVTLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSL--- 82
+G E V +E+V L C + + ++W+++ RP EPR +
Sbjct: 883 LGEELNVSVVANESVALECQSHAMPPPVLSWWKDG-------------RPLEPRPGVHLS 929
Query: 83 VDATSLHIESLSLGDEGIYTCQEILNVTQWFQVWLQVASGPYQIEVHIVATGTLPNG-TL 141
D L ++ + D G YTC+ + + + Y + V + L TL
Sbjct: 930 ADKALLQVDRADVWDAGHYTCEALNQAGR--------SEKHYNLNVWVAPVFPLRESHTL 981
Query: 142 YAARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISPNL---QGN 198
G SC P P + W E G LL + +G
Sbjct: 982 TVREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGT 1041
Query: 199 YTCLALNQLSKRHRKVTTELLVYYPP----PSAPQCWAQMASGSFMLQLTCRWDGGYPDP 254
YTC N + + + E V+ PP P P + + L C G P P
Sbjct: 1042 YTCECSNVVGNSSQDLQLE--VHVPPQIAGPREPPTQVSVVQDG-VATLECNATGK-PPP 1097
Query: 255 DFLWIEEPGGVIVGKSKLGVEMLSE--------SQLSDGKKFKCVTSHIVGPESGASCMV 306
W E G VG ++LG+++ ++ +Q + ++ CV ++ G +
Sbjct: 1098 TVTW--ERDGQPVG-AELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGRAERKFELS 1154
Query: 307 QIRGPSLLSE--PMK--TCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHL 362
+ P L+ + P+ T +TL C+ G PPA I W R E + P
Sbjct: 1155 VLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPA-IRWFRG----EEPVSPGEDTY 1209
Query: 363 ITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEPLNI 411
+ G +T +Q+ D G Y C A + G + V P +I
Sbjct: 1210 LLAGGWMLKMTQ---TQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSI 1255
Score = 57.4 bits (137), Expect = 3e-08
Identities = 69/296 (23%), Positives = 110/296 (37%), Gaps = 33/296 (11%)
Query: 124 YQIEVHIVATGTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTV 183
YQ+ VH+ T + V +C+S+ P P V W + G+ ++
Sbjct: 2658 YQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSP 2717
Query: 184 N-FFSLLLISPNLQGNYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSFMLQ 242
+ + P G YTC A N H+ V L V P P A +
Sbjct: 2718 SGALEIGQALPIHAGRYTCSARNSAGVAHKHVF--LTVQASPVVKPLPSVVRAVAEEEVL 2775
Query: 243 LTCRWDGGYPDPDFLWIEEPGGVIVGKSKL----GVEMLSESQLSDGKKFKCVTSHIVGP 298
L C G P P W +E V G S G ++ + D + C+ + G
Sbjct: 2776 LPCE-ASGIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGS 2834
Query: 299 ESGASCMVQIRGPSLLSEPMKTCFT--GGNVTLTCQVSGAYPPAKILWLRNLTQP----- 351
G + +V ++ P ++ + T G + L C+ G+ P I W ++ QP
Sbjct: 2835 AMGKTRLV-VQVPPVIENGLPDLSTTEGSHAFLPCKARGS-PEPNITWDKD-GQPVSGAE 2891
Query: 352 -EVIIQPSSRHLITQ-DGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSV 405
+ IQPS L+ +GQ D G Y C A++ VG + L++
Sbjct: 2892 GKFTIQPSGELLVKNLEGQ-------------DAGTYTCTAENAVGRARRRVHLTI 2934
Score = 57.4 bits (137), Expect = 3e-08
Identities = 67/274 (24%), Positives = 109/274 (39%), Gaps = 25/274 (9%)
Query: 143 AARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISPNLQGNYTCL 202
A +V C +S P P + W + LN ++ L + SP GNY C+
Sbjct: 2768 AVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCI 2827
Query: 203 ALNQLSKRHRKVTTELLVYYPPP---SAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWI 259
A N K T L+V PP P S +F L C+ G P+P+ W
Sbjct: 2828 AKNSAGSAMGK--TRLVVQVPPVIENGLPDLSTTEGSHAF---LPCKARGS-PEPNITWD 2881
Query: 260 EEPGGVIVGKSKLGVE-----MLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSLL 314
++ V + K ++ ++ + D + C + VG + + P
Sbjct: 2882 KDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLPVFT 2941
Query: 315 SEPM-KTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLT 373
+ P ++ G + L C G+ P +I W N +P + + QDG STL
Sbjct: 2942 TLPGDRSLRLGDRLWLRCAARGS-PTPRIGWTVN-------DRPVTEGVSEQDG-GSTLQ 2992
Query: 374 IHNCSQDLDEGYYICRADSPVGVREMEIWLSVKE 407
S++ D G Y+C A++ VG + ++ VKE
Sbjct: 2993 RAAVSRE-DSGTYVCWAENRVGRTQAVSFVHVKE 3025
Score = 55.5 bits (132), Expect = 1e-07
Identities = 86/375 (22%), Positives = 136/375 (36%), Gaps = 43/375 (11%)
Query: 36 VHENVTLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSLVDATSLHIESLSL 95
++ +V+L C + +VTWY+++ +L E F L +L + L
Sbjct: 1760 LNSSVSLPCDVHAHPNPEVTWYKDSQ----------ALSLGEEVFLLPGTHTLQLGRARL 1809
Query: 96 GDEGIYTCQEILNVTQWFQVWLQVASGPYQIEVHIVATGTLPNGTLYAARGSQVDFSCNS 155
D G+YTC E LN Q +Q++ + P + G + SC +
Sbjct: 1810 SDSGMYTC-EALNAAGRDQKLVQLS---VLVPPAFRQAPRGPQDAVLVRVGDKAVLSCET 1865
Query: 156 SSRPPPVVEWW------FQALNSSSESFGHNLTVNFFSLLLISPNLQGNYTCLALNQLSK 209
+ P P V W+ A + + G L + + + +G Y+C N +
Sbjct: 1866 DALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQV-----SDKGLYSCKVSNVAGE 1920
Query: 210 RHRKVTTELLVYYPPP-SAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWIE-----EPG 263
R T L V PP P+ L LTC G P P W++ E
Sbjct: 1921 AVRTFT--LTVQVPPTFENPKTETVSQVAGSPLVLTCD-VSGVPAPTVTWLKDRMPVESS 1977
Query: 264 GVIVGKSKLGVEMLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSLLSEPMKT--- 320
V S+ G LS Q + + CV + + + P + S +
Sbjct: 1978 AVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHH 2037
Query: 321 CFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQD 380
G V L C+ G PP + WL++ + + P R + DG + L S
Sbjct: 2038 VLEGQEVRLDCEADG-QPPPDVAWLKDGSPLGQDMGPHLRFYL--DGGSLVLKGLRAS-- 2092
Query: 381 LDEGYYICRADSPVG 395
D G Y C A +P G
Sbjct: 2093 -DAGAYTCVAHNPAG 2106
Score = 55.5 bits (132), Expect = 1e-07
Identities = 94/389 (24%), Positives = 140/389 (35%), Gaps = 51/389 (13%)
Query: 28 LEAVVIGEVHENVTLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSLVDATS 87
L +VV E V L C R +TW + +S+ ++
Sbjct: 2762 LPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQ-----------VLPGGQ 2810
Query: 88 LHIESLSLGDEGIYTCQEILNVTQWFQVWLQVASGPYQIEVHI--VATGTLPNGTLYAAR 145
L I S D G Y C + A G ++ V + V LP+ L
Sbjct: 2811 LRIAHASPEDAGNYLCIAKNSAGS--------AMGKTRLVVQVPPVIENGLPD--LSTTE 2860
Query: 146 GSQVDFSCNSSSRPPPVVEWWF--QALNSSSESFGHNLTVNFFSLLLISPNLQGN----Y 199
GS C + P P + W Q ++ + F T+ LL+ NL+G Y
Sbjct: 2861 GSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKF----TIQPSGELLVK-NLEGQDAGTY 2915
Query: 200 TCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWI 259
TC A N + + R+V +LV + P + L+ R G P P W
Sbjct: 2916 TCTAENAVGRARRRVHLTILVLPVFTTLPGDRSLRLGDRLWLRCAAR---GSPTPRIGWT 2972
Query: 260 EEPGGVIVGKSKL-GVEMLSESQLS--DGKKFKCVTSHIVGPESGASCMVQIRGPSLLSE 316
V G S+ G L + +S D + C + VG S + P L E
Sbjct: 2973 VNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQGE 3032
Query: 317 PMKTCF--TGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTI 374
GG++ L C V G P I W+++ P + QN +LTI
Sbjct: 3033 AFSYLVEPVGGSIQLDCVVRGD-PVPDIHWIKDGL-------PLRGSHLRHQLQNGSLTI 3084
Query: 375 HNCSQDLDEGYYICRADSPVGVREMEIWL 403
H +D D G Y C A++ +GV + + L
Sbjct: 3085 HRTERD-DAGRYQCLAENEMGVAKKVVIL 3112
Score = 54.3 bits (129), Expect = 3e-07
Identities = 83/361 (22%), Positives = 127/361 (35%), Gaps = 62/361 (17%)
Query: 84 DATSLHIESLSLGDEGIYTCQEILNVTQWFQVWLQVASGP-------YQIEVHI-----V 131
D + L +ES G+Y+C VAS P Y +EV + V
Sbjct: 457 DGSVLRLESPGEASSGLYSC---------------VASSPAGEAVLQYSVEVQVPPQLLV 501
Query: 132 ATGTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLL- 190
A G G + G ++ C +S P P ++ W Q + E G + +L +
Sbjct: 502 AEGL---GQVTTIVGQPLELPCQASGSPVPTIQ-WLQNGRPAEELAGVQVASQGTTLHID 557
Query: 191 -ISPNLQGNYTCLALNQLSKRHRKVTTELLVYYPP-----PSAPQCWAQMASGSFMLQL- 243
+ + G + C A N+ +V + + P P W SF
Sbjct: 558 HVELDHSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLEVPIGQYHWGXEHHSSFPAACD 617
Query: 244 --TCRWDGGYPDPDF---------LWIEEPGGVIVGKSKLGVEMLSESQLSDGKKFKCVT 292
R G +P P LW EP G+ V S + + L D + C
Sbjct: 618 PPVHRGWGAHPKPPLVEGWCSPGSLW-GEPTGIPVAYSLPPPLQIEKVDLRDEGIYTCAA 676
Query: 293 SHIVGPESGASCMVQIRGPSLLSEPM-KTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQP 351
+++ G + + P++ P+ K +VTL C SG PP + W +
Sbjct: 677 TNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLECLASGV-PPPDVSWFKG---- 731
Query: 352 EVIIQPSSRHL-ITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEPLN 410
QP S + +T L I +Q D G Y C A + G E+ L V P
Sbjct: 732 ---HQPVSSWMGVTVSVDGRVLRIEQ-AQLSDAGSYRCVASNVAGSTELRYGLRVNVPPR 787
Query: 411 I 411
I
Sbjct: 788 I 788
Score = 52.8 bits (125), Expect = 8e-07
Identities = 97/432 (22%), Positives = 155/432 (35%), Gaps = 69/432 (15%)
Query: 28 LEAVVIGEVHENVTLH---CGNISGLRGQVTWYRN-NSEPVFLLSSNSSLRPAEPRFSLV 83
LE +G+V V L CG + QVTW + +SEP+ +P +++
Sbjct: 5 LEIKGLGDVALTVGLEAGGCGTHGTPKPQVTWRKGPSSEPLH----------GQPGVAVL 54
Query: 84 DATSLHIESLSLGDEGIYTCQEILNVTQWFQVWLQVASGPYQIEVHIVATGTLPNGTLYA 143
+ SL + S+S D G Y CQ V + V P I G N + A
Sbjct: 55 EEGSLFLASVSPADSGDYECQATNEVGSTSRRAKLVVYVPPSIR----EDGRKANVSGMA 110
Query: 144 ARGSQVDFSCNSSSRPPPVVEWWFQALNSS--------------SESFGHNLTVNFFSLL 189
G + C+++ P P + W A + GH L SL
Sbjct: 111 --GQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLH 168
Query: 190 L--ISPNLQGNYTCLALNQL-SKRHRKVTTELLVYYP------PPSAPQCWAQMASGSFM 240
I P G A +K +P PP+ P A+ +
Sbjct: 169 FPRIQPGRSGRRGAQAGGSAQTKAPWXAGLAGFEQFPTPHAFSPPAPPSVLGAGAAQEVL 228
Query: 241 ------LQLTCRWDGGYPDPDFLWIEEPGGVIVGKSKLGVE------MLSESQLSDGKKF 288
++L C W G P P W ++ V+ G L V+ ++ S + D ++
Sbjct: 229 GLAGADVELQC-WTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRY 287
Query: 289 KCVTSHIVGPESGASCMVQIRGPSLLSEPMKT----CFTGGNVTLTCQVSGAYPPAKILW 344
+CV G ++ +++ P + +T V L C+ G P I W
Sbjct: 288 QCVAFSPAGQQA-RDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLCEARGV-PTPNITW 345
Query: 345 LRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLS 404
++ ++ S++ + T+ G+ L +Q D G Y C+A + VG E L
Sbjct: 346 FKD----GALLPTSTKVVYTRGGRQLQL---GRAQSSDAGVYTCKASNAVGAAEKATRLD 398
Query: 405 VKEPLNIGGIVG 416
V P I G G
Sbjct: 399 VYVPPTIEGAGG 410
Score = 52.4 bits (124), Expect = 1e-06
Identities = 89/377 (23%), Positives = 147/377 (38%), Gaps = 56/377 (14%)
Query: 41 TLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSLVD-ATSLHIESLSLGDEG 99
TL C VTW R+ +PV AE L + SLH+E G
Sbjct: 1086 TLECNATGKPPPTVTWERDG-QPV----------GAELGLQLQNQGQSLHVERAQAAHTG 1134
Query: 100 IYTC-QEILNVTQWFQVWLQVASGPYQIEVHIVATGTL-PNGTLYAARGSQVDFSCNSSS 157
Y+C E L + L V P I G L P + AA S + C +
Sbjct: 1135 RYSCVAENLAGRAERKFELSVLVPPELI-------GDLDPLTNITAALHSPLTLLCEAMG 1187
Query: 158 RPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISPNLQ--GNYTCLALNQLSKRHRKVT 215
PPP + WF+ S L + L + Q G Y+CLA N+ + R +
Sbjct: 1188 IPPPAIR-WFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFS 1246
Query: 216 TELLVYYPPPSAPQCWAQM------ASGSFMLQLTCRWDGGYPDPDFLWIEEPGGVIVGK 269
E+LV PP + ++ + M +T G+P P W ++ + G
Sbjct: 1247 VEVLV--PPSIENEDLEEVIKVLDGQTAHLMCNVT-----GHPQPKLTWFKDGRPLARGD 1299
Query: 270 ----SKLGVEM-LSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSLL------SEPM 318
S GV + + ++ LS + C+ ++ VG ++ + + P++L ++
Sbjct: 1300 AHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEE 1359
Query: 319 KTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCS 378
T ++L C+ A+P I W+++ E +SR++ G + L I N
Sbjct: 1360 VTVTVNNPISLICEAL-AFPSPNITWMKDGAPFE-----ASRNIQLLPGTHG-LQILNAQ 1412
Query: 379 QDLDEGYYICRADSPVG 395
++ D G Y C + +G
Sbjct: 1413 KE-DAGQYTCVVTNELG 1428
Score = 49.3 bits (116), Expect = 9e-06
Identities = 83/354 (23%), Positives = 126/354 (35%), Gaps = 62/354 (17%)
Query: 83 VDATSLHIESLSLGDEGIYTCQEILNVTQWFQVWLQVASGP-------YQIEVHIVAT-- 133
+D SL ++ L D G YTC VA P + + V + T
Sbjct: 2079 LDGGSLVLKGLRASDAGAYTC---------------VAHNPAGEDARLHTVNVLVPPTIK 2123
Query: 134 -GTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWWFQAL------NSSSESFGHNLTVNFF 186
G +GTL + G V C PP V W L + GH L ++
Sbjct: 2124 QGADGSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKV 2183
Query: 187 SLLLISPNLQGNYTCLALNQLSKRHRKVTTELLVYYPPPSAP---QCWAQMASGSFMLQL 243
L G +TC+A + R T ++ V PP P Q + GS +++L
Sbjct: 2184 QLADA-----GIFTCVAASPAGVADRNFTLQVQV--PPVLEPVEFQNDVVVVRGS-LVEL 2235
Query: 244 TCRWDGGYPDPDFLWIEEPGGVIVGKSKLGVEMLSESQ-LSDGKKFKCVTSHIVGPESGA 302
C G P P W+++ ++ + G + E+ D + CV G
Sbjct: 2236 PCE-ARGVPLPLVSWMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRH 2294
Query: 303 SCMVQIRGPSL--LSEPMKTCFT-GGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSS 359
+ + P + +P + T G + L C G P I W ++
Sbjct: 2295 FQLTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGT-PQPNITWHKD------------ 2341
Query: 360 RHLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEPLNIGG 413
+T+ NS T + D G Y C A+SP G E + V+ P NI G
Sbjct: 2342 GQALTRLENNSRAT--RVLRVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVG 2393
Score = 48.9 bits (115), Expect = 1e-05
Identities = 98/489 (20%), Positives = 176/489 (35%), Gaps = 86/489 (17%)
Query: 2 AAGGSAPEPRVLVCLGALLAGWVAVGLEAVVIGEVHENVTLHCGNISGLRGQVTWYRNNS 61
A G ++ V L + G + V V+ ++L C ++ +TW ++ +
Sbjct: 1330 AVGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMKDGA 1389
Query: 62 EPVFLLSSNSSLRPAEPRFSLVDATSLHIESLSLGDEGIYTC---QEILNVTQWFQVWL- 117
F S N L P +++A D G YTC E+ + + V +
Sbjct: 1390 P--FEASRNIQLLPGTHGLQILNAQK--------EDAGQYTCVVTNELGEAVKNYHVEVL 1439
Query: 118 ---QVASGPYQIEVHIVATGTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWWFQALNSSS 174
++ EV + T N TL C S + PPP + W+ +
Sbjct: 1440 IPPSISKDDPLGEVGVKEVKTKVNSTL--------TLECESWAVPPPTIRWYKDGQPVTP 1491
Query: 175 ESFGHNLTVNFFSLLLISPNL---QGNYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCW 231
S + LL I P G Y C+A N + + +L+ PP +
Sbjct: 1492 SS--RLQVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDF--NVLIQVPP-----MF 1542
Query: 232 AQMASGSFMLQLTCRWD---GG---------------------YPDPDFLWIEEPG---- 263
++ S ++ R + GG P PD W E
Sbjct: 1543 QKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWYREDQPLSA 1602
Query: 264 ----GVIVGKSKLGVEMLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSLLSEPMK 319
V+ G L + ++ + + ++ C S+ VG + ++ + P +L + +
Sbjct: 1603 GDEVSVLQGGRVLQIPLV---RAENAGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEE 1659
Query: 320 -----TCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTI 374
T V+L C G P I WL+N + PS R + +DGQ +
Sbjct: 1660 LVEEVTVNASSTVSLQCPALG-NPVPTISWLQN----GLPFSPSPRLQVLEDGQVLQV-- 1712
Query: 375 HNCSQDLDEGYYICRADSPVGVREMEIWLSVKEPLNIGGI-VGTIVSLLLLGLAIISGLL 433
+ ++ D Y+C A++ G E L V+ P I G+ + + ++L +++ +
Sbjct: 1713 -STAEVADAASYMCVAENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVH 1771
Query: 434 LHYSPVFCW 442
H +P W
Sbjct: 1772 AHPNPEVTW 1780
Score = 45.4 bits (106), Expect = 1e-04
Identities = 89/407 (21%), Positives = 153/407 (37%), Gaps = 63/407 (15%)
Query: 35 EVHENVTLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSLVDATSLHIESLS 94
+V+ +TL C + + + WY++ +PV P+ L + L I+
Sbjct: 1461 KVNSTLTLECESWAVPPPTIRWYKDG-QPV---------TPSSRLQVLGEGRLLQIQPTQ 1510
Query: 95 LGDEGIYTCQEILNVT----QWFQVWLQVAS-----GPYQIEVHIVATGTLPNGTLYAAR 145
+ D G Y C NV Q F V +QV G + I++ G + R
Sbjct: 1511 VSDSGRYLCVAT-NVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYR 1569
Query: 146 ----GSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTV----NFFSLLLISPNLQG 197
+ C++++ PPP + W+ + S G ++V + L+ G
Sbjct: 1570 EIVENNPAYLYCDTNAIPPPDLTWYRE---DQPLSAGDEVSVLQGGRVLQIPLVRAENAG 1626
Query: 198 NYTCLALNQLSKRHRKVTTELLVYYPP----PSAPQCWAQMASGSFMLQLTCRWDGGYPD 253
Y+C A N++ + + ELLV PP + + S + L C G P
Sbjct: 1627 RYSCKASNEVGEDW--LHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALGN-PV 1683
Query: 254 PDFLWIE-----EPGGVIVGKSKLGVEMLSESQLSDGKKFKCVTSHIVG-PESGASCMVQ 307
P W++ P + V +S ++++D + CV + G E + VQ
Sbjct: 1684 PTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGSAEKLFTLRVQ 1743
Query: 308 IRGPSL--LSEPMKTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQ----PEVIIQPSSRH 361
+ P + L T +V+L C V A+P ++ W ++ EV + P +
Sbjct: 1744 V-PPRIAGLDLEQVTAILNSSVSLPCDVH-AHPNPEVTWYKDSQALSLGEEVFLLPGTHT 1801
Query: 362 LITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEP 408
L + S D G Y C A + G + + LSV P
Sbjct: 1802 LQLGRARLS-----------DSGMYTCEALNAAGRDQKLVQLSVLVP 1837
Score = 44.7 bits (104), Expect = 2e-04
Identities = 82/349 (23%), Positives = 127/349 (36%), Gaps = 37/349 (10%)
Query: 73 LRPAEPRFSLVDATSLHIESLSLGDEGIYTCQEILNVTQWFQVW-LQVASGPYQIEVHIV 131
L P PRF ++ SL I+ + D G Y C + Q L+V P
Sbjct: 2522 LDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEPP-------- 2573
Query: 132 ATGTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWW--FQALNSSSESFGHNLTVNFFSLL 189
A P+ A + C +S P P+V WW Q L+ + + L + +LL
Sbjct: 2574 AIAPSPSNLTLTAHTPAL-LPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPS-NALL 2631
Query: 190 LISPNLQ--GNYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRW 247
L +P Q + C+ N++ + HR ++ V+ PP A + + LTC
Sbjct: 2632 LTAPGPQDSAQFECVVSNEVGEAHR--LYQVTVHVPPTIADDQTDFTVTMMAPVVLTCH- 2688
Query: 248 DGGYPDPDFLWIEEPGGVIVGKSKLGVEMLSESQLSDGK-------KFKCVTSHIVGPES 300
G P P W G +G G + L G+ ++ C + G
Sbjct: 2689 STGIPAPTVSW--SKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAGVAH 2746
Query: 301 GASCMVQIRGPSLLSEP-MKTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSS 359
+ P + P + V L C+ SG P I W Q E + +
Sbjct: 2747 KHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASG-IPRPTITW-----QKEGLNVATG 2800
Query: 360 RHLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEP 408
+ TQ L I + S + D G Y+C A + G + L V+ P
Sbjct: 2801 --VSTQVLPGGQLRIAHASPE-DAGNYLCIAKNSAGSAMGKTRLVVQVP 2846
Score = 44.3 bits (103), Expect = 3e-04
Identities = 68/290 (23%), Positives = 115/290 (39%), Gaps = 41/290 (14%)
Query: 142 YAARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISPNLQ----G 197
+ G +V C + +PPP V W + + + G +L L+ L+ G
Sbjct: 2037 HVLEGQEVRLDCEADGQPPPDVA-WLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAG 2095
Query: 198 NYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSF------MLQLTCRWDGGY 251
YTC+A N + R T +LV PP+ Q SG+ ++ + C G
Sbjct: 2096 AYTCVAHNPAGEDARLHTVNVLV---PPTIKQ--GADGSGTLVSRPGELVTMVCPVRGS- 2149
Query: 252 PDPDFLWIEEPGGVIVGKSKL-----GVEMLSESQLSDGKKFKCVTSHIVGPESGASCMV 306
P W+++ + + + L +S+ QL+D F CV + G + + +
Sbjct: 2150 PPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAG-VADRNFTL 2208
Query: 307 QIRGPSLLSEPMK-----TCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRH 361
Q++ P +L EP++ G V L C+ G P + W+++ E ++ S
Sbjct: 2209 QVQVPPVL-EPVEFQNDVVVVRGSLVELPCEARGV-PLPLVSWMKD---GEPLLSQS--- 2260
Query: 362 LITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEPLNI 411
+ G + L D G Y C A S G L+V EP +I
Sbjct: 2261 --LEQGPSLQLEAVGAG---DSGTYSCVAVSEAGEARRHFQLTVMEPPHI 2305
Score = 43.9 bits (102), Expect = 4e-04
Identities = 86/361 (23%), Positives = 135/361 (37%), Gaps = 59/361 (16%)
Query: 71 SSLRPAEPRFS--LVDATSLHIESLSLGDEGIYTC---QEILNVTQWFQVWLQVASGPYQ 125
S ++ EP S L SL +E++ GD G Y+C E + FQ L V P
Sbjct: 2248 SWMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQ--LTVMEPP-- 2303
Query: 126 IEVHIVATGTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWW--FQALNSSSESFGHNLTV 183
HI +G L G+ ++ C++ P P + W QAL L
Sbjct: 2304 ---HIEDSGQPTE--LSLTPGAPMELLCDAQGTPQPNITWHKDGQALT--------RLEN 2350
Query: 184 NFFSLLLISPNLQGNYTCLALNQLSKRHRKVTTELLVYYPP----PSAPQCWAQMASGSF 239
N + ++ G YTCLA + + + + V PP P P+ +A G
Sbjct: 2351 NSRATRVLRVRDAGLYTCLAESPAGAIEK--SFRVRVQAPPNIVGPRGPRFVVGLAPGQL 2408
Query: 240 MLQLTCRWDGGYPDPDFLWIEEPGGVIVGKSK----------LGVEMLSESQLSDGKKFK 289
+L+ + + P P W + G+++ + L ++ LS + D +
Sbjct: 2409 VLECSVEAE---PAPKITWHRD--GIVLQEDAHTQFPERGRFLQLQALSTADSGD---YS 2460
Query: 290 CVTSHIVGPESGASCMVQIRGPSLLS-EPMKTCFTGGNVTLTCQVSGAYPPAKILWLRNL 348
C + G S A + P++ S P L CQ G P + W ++
Sbjct: 2461 CTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGV-PAPLVSWRKD- 2518
Query: 349 TQPEVIIQP-SSRHLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKE 407
V + P S R I +G +L I D G+Y+C A + G L V E
Sbjct: 2519 ---RVPLDPRSPRFEILPEG---SLRIQPVLAQ-DAGHYLCLASNSAGSDRQGRDLRVLE 2571
Query: 408 P 408
P
Sbjct: 2572 P 2572
Score = 43.5 bits (101), Expect = 5e-04
Identities = 65/282 (23%), Positives = 109/282 (38%), Gaps = 36/282 (12%)
Query: 146 GSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISPNL----QGNYTC 201
G+ V+ C +S P P VEW G +L V +L +G Y C
Sbjct: 232 GADVELQCWTSGVPTPQVEWTKD--RQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQC 289
Query: 202 LALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASG------SFMLQLTCRWDGGYPDPD 255
+A + ++ R +L V+ P P W +G ++QL C G P P+
Sbjct: 290 VAFSPAGQQARDF--QLRVHAP----PTIWGSNETGEVAVMEDHLVQLLCE-ARGVPTPN 342
Query: 256 FLWIEE----PGGVIVGKSKLGVEM-LSESQLSDGKKFKCVTSHIVGPESGASCMVQIRG 310
W ++ P V ++ G ++ L +Q SD + C S+ VG A+ +
Sbjct: 343 ITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYVP 402
Query: 311 PSLLSEP----MKTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQD 366
P++ + G V L C V+ +P + W + + S+ + D
Sbjct: 403 PTIEGAGGRPYVVKAVAGRPVALEC-VARGHPSPTLSW----HHEGLPVAESNESRLETD 457
Query: 367 GQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEP 408
G S L + + + G Y C A SP G ++ + V+ P
Sbjct: 458 G--SVLRLES-PGEASSGLYSCVASSPAGEAVLQYSVEVQVP 496
Score = 35.0 bits (79), Expect = 0.17
Identities = 80/363 (22%), Positives = 134/363 (36%), Gaps = 63/363 (17%)
Query: 197 GNYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASG--------SFMLQLTCRWD 248
G YTC+ N+L + + E+L+ PPS + G + L L C
Sbjct: 1417 GQYTCVVTNELGEAVKNYHVEVLI---PPSISKDDPLGEVGVKEVKTKVNSTLTLECE-S 1472
Query: 249 GGYPDPDFLWIEEPGGVIVGKSKLGV------EMLSESQLSDGKKFKCVTSHIVGPESGA 302
P P W ++ G + S+L V + +Q+SD ++ CV +++ G E
Sbjct: 1473 WAVPPPTIRWYKD-GQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVATNVAG-EDDQ 1530
Query: 303 SCMVQIRGPSLLSE--PMKTCF--------TGGNVT------------LTCQVSGAYPPA 340
V I+ P + + F G VT L C + A PP
Sbjct: 1531 DFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYCD-TNAIPPP 1589
Query: 341 KILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREME 400
+ W R QP + + Q G+ + + + G Y C+A + VG +
Sbjct: 1590 DLTWYRE-DQP---LSAGDEVSVLQGGRVLQIPLVRAE---NAGRYSCKASNEVGEDWLH 1642
Query: 401 IWLSVKEPLNIGGIVGTIVSLLLLGLAIISGL----LLHYSPVFCW-----KVGNTSRGQ 451
L V P I G +V + + + L L + P W + R Q
Sbjct: 1643 YELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQ 1702
Query: 452 NMDDVMVLVDSEEEEEEEEE---EEEDAAVGEQEGAREREELPKEIPKQDHIHRVTALVN 508
++D VL S E + E+ A ++ R ++P I D + +VTA++N
Sbjct: 1703 VLEDGQVLQVSTAEVADAASYMCVAENQAGSAEKLFTLRVQVPPRIAGLD-LEQVTAILN 1761
Query: 509 GNI 511
++
Sbjct: 1762 SSV 1764
Score = 31.2 bits (69), Expect = 2.5
Identities = 37/170 (21%), Positives = 62/170 (36%), Gaps = 10/170 (5%)
Query: 146 GSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISPNLQGNYTCLALN 205
G + C P P + W L H L ++ + G Y CLA N
Sbjct: 3042 GGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAEN 3101
Query: 206 QLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWIEEPGGV 265
++ +KV +L P + SG + L C+ G P P W+ + G
Sbjct: 3102 EMGVA-KKVVILVLQSAPVFQVEPQDMTVRSGD-DVALRCQ-ATGEPTPTIEWL-QAGQP 3157
Query: 266 IVGKSKL-----GVEMLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRG 310
+ +L G L + D + CV +++G + + +V +RG
Sbjct: 3158 LRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNLLGSATARAFLV-VRG 3206
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 67.4 bits (163), Expect = 3e-11
Identities = 95/370 (25%), Positives = 147/370 (39%), Gaps = 52/370 (14%)
Query: 74 RPAEPRFSLVDA---TSLHIESLSLGDEGIYTCQEILNV-TQWFQVWLQV----ASGPYQ 125
RPAE + A T+LHI+ + L G++ CQ T +V + V A G +
Sbjct: 446 RPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLE 505
Query: 126 IEVHIVATGTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNF 185
+ + G + + AA V + + PP+VE W + E G + +
Sbjct: 506 VPIGQYHWGXEHHSSFPAACDPPVHRGWGAHPK-PPLVEGWCSPGSLWGEPTGIPVAYSL 564
Query: 186 ---FSLLLISPNLQGNYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSFMLQ 242
+ + +G YTC A N + R+V ++LV PP P + + +
Sbjct: 565 PPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLV--PPNIEPGPVNKAVLENASVT 622
Query: 243 LTCRWDGGYPDPDFLWIEEPGGVIVGKSKLGVEM--------LSESQLSDGKKFKCVTSH 294
L C G P PD W + V S +GV + + ++QLSD ++CV S+
Sbjct: 623 LEC-LASGVPPPDVSWFKGHQPV---SSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASN 678
Query: 295 IVGPES---GASCMVQIR--------GPSLLSEPMKTCFTGGNVTLTCQVSGAYPPAKIL 343
+ G G V R GP L++ P V LTC +GA P ++
Sbjct: 679 VAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTP---------VRLTCNATGA-PSPTLM 728
Query: 344 WLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWL 403
WL++ P + + G+ TL S D G Y C A S VG ++ L
Sbjct: 729 WLKDGNPVSPAGTPGLQ--VFPGGRVLTLASARAS---DSGRYSCVAVSAVGEDRQDVVL 783
Query: 404 SVKEPLNIGG 413
V P +I G
Sbjct: 784 QVHMPPSILG 793
Score = 65.5 bits (158), Expect = 1e-10
Identities = 88/339 (25%), Positives = 140/339 (41%), Gaps = 39/339 (11%)
Query: 88 LHIESLSLGDEGIYTCQEI-LNVTQWFQVWLQVASGPYQIEVHIVATGTLPNGTLYAARG 146
L IE + L DEGIYTC L +V L+V P IE V L N
Sbjct: 568 LQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPP-NIEPGPVNKAVLEN-------- 618
Query: 147 SQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISPNLQ--GNYTCLAL 204
+ V C +S PPP V WF+ S G ++V+ L + L G+Y C+A
Sbjct: 619 ASVTLECLASGVPPPDVS-WFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVAS 677
Query: 205 NQLSKRHRKVTTELLVYYPPP-SAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWIEEPG 263
N ++ L V PP + P + ++LTC G P P +W+++ G
Sbjct: 678 NVAGS--TELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGA-PSPTLMWLKD-G 733
Query: 264 GVIVGKSKLGVEM--------LSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSLLS 315
+ G+++ L+ ++ SD ++ CV VG + + PS+L
Sbjct: 734 NPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILG 793
Query: 316 EPMKTCFTGG-NVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTI 374
E + +V L CQ S A PP + W ++ +P ++P ++ D L
Sbjct: 794 EELNVSVVANESVALECQ-SHAMPPPVLSWWKD-GRP---LEPRPGVHLSAD---KALLQ 845
Query: 375 HNCSQDLDEGYYICRADSPVGVRE----MEIWLSVKEPL 409
+ + D G+Y C A + G E + +W++ PL
Sbjct: 846 VDRADVWDAGHYTCEALNQAGHSEKHYNLNVWVAPVFPL 884
Score = 61.2 bits (147), Expect = 2e-09
Identities = 86/381 (22%), Positives = 146/381 (38%), Gaps = 43/381 (11%)
Query: 31 VVIGEVHENVTLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSLV-DATSLH 89
V++G+ E V N S N P N PR ++ D L
Sbjct: 1561 VILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQ 1620
Query: 90 IESLSLGDEGIYTC---QEILNVTQWFQVWLQVASGPYQIEVHIVATGTLPNGTLYAARG 146
+ + + D Y C + + + F + +QV +++ V A
Sbjct: 1621 VSTAEVADAASYMCVAENQAGSAEKLFTLRVQVPPRIAGLDLEQVT----------AILN 1670
Query: 147 SQVDFSCNSSSRPPPVVEWW--FQALNSSSESFGHNLTVNFFSLLLISPNL--QGNYTCL 202
S V C+ + P P V W+ QAL+ E F L +L L L G YTC
Sbjct: 1671 SSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVF---LLPGTHTLQLGRARLSDSGMYTCE 1727
Query: 203 ALNQLSKRHRKVTTELLV---YYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWI 259
ALN + + V +LV + P PQ + G + L+C D P+P W
Sbjct: 1728 ALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAV-LSCETD-ALPEPTVTWY 1785
Query: 260 EEPGGVIVGKSKLGVE-----MLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSLL 314
++ +++ + + + E+Q+SD + C S++ G E+ + + ++ P
Sbjct: 1786 KDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAG-EAVRTFTLTVQVPPTF 1844
Query: 315 SEPMKTCFT---GGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNST 371
P + G + LTC VSG P + WL++ + ++ S+ H + G
Sbjct: 1845 ENPKTETVSQVAGSPLVLTCDVSGV-PAPTVTWLKD----RMPVESSAVHGVVSRGGRLQ 1899
Query: 372 LTIHNCSQDLDEGYYICRADS 392
L + Q G Y C A++
Sbjct: 1900 L---SRLQPAQAGTYTCVAEN 1917
Score = 60.8 bits (146), Expect = 3e-09
Identities = 87/356 (24%), Positives = 143/356 (40%), Gaps = 50/356 (14%)
Query: 88 LHIESLSLGDEGIYTCQEILNVTQWFQ-VWLQVASGPY----QIEVHIVATGTLPNGTLY 142
L + S D G Y+C + V + Q V LQV P ++ V +VA
Sbjct: 753 LTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVSVVAN--------- 803
Query: 143 AARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISPNL--QGNYT 200
V C S + PPPV+ WW G +L+ + L + ++ G+YT
Sbjct: 804 ----ESVALECQSHAMPPPVLSWWKDGRPLEPRP-GVHLSADKALLQVDRADVWDAGHYT 858
Query: 201 CLALNQL--SKRHRKVTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLW 258
C ALNQ S++H + + +P + + + L CR G P P W
Sbjct: 859 CEALNQAGHSEKHYNLNVWVAPVFPLRESHTLTVREGHPT-RLSCECR---GVPFPKISW 914
Query: 259 IEE------PGGVIVGKSKLG-VEMLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGP 311
++ G + S +G + L ++QL+ + C S++VG S +++ P
Sbjct: 915 RKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVG-NSSQDLQLEVHVP 973
Query: 312 SLLSEPMK-----TCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQD 366
++ P + + G TL C +G PP + W R+ QP L Q
Sbjct: 974 PQIAGPREPPTQVSVVQDGVATLECNATGK-PPPTVTWERD-------GQPVGAELGLQ- 1024
Query: 367 GQNSTLTIH-NCSQDLDEGYYICRADSPVGVREMEIWLSVKEPLNIGGIVGTIVSL 421
QN ++H +Q G Y C A++ G E + LSV P + G + + ++
Sbjct: 1025 LQNQGQSLHVERAQAAHTGRYSCVAENLAGRAERKFELSVLVPPELIGDLDPLTNI 1080
Score = 57.4 bits (137), Expect = 3e-08
Identities = 69/296 (23%), Positives = 110/296 (37%), Gaps = 33/296 (11%)
Query: 124 YQIEVHIVATGTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTV 183
YQ+ VH+ T + V +C+S+ P P V W + G+ ++
Sbjct: 2567 YQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSP 2626
Query: 184 N-FFSLLLISPNLQGNYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSFMLQ 242
+ + P G YTC A N H+ V L V P P A +
Sbjct: 2627 SGALEIGQALPIHAGRYTCSARNSAGVAHKHVF--LTVQASPVVKPLPSVVRAVAEEEVL 2684
Query: 243 LTCRWDGGYPDPDFLWIEEPGGVIVGKSKL----GVEMLSESQLSDGKKFKCVTSHIVGP 298
L C G P P W +E V G S G ++ + D + C+ + G
Sbjct: 2685 LPCE-ASGIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGS 2743
Query: 299 ESGASCMVQIRGPSLLSEPMKTCFT--GGNVTLTCQVSGAYPPAKILWLRNLTQP----- 351
G + +V ++ P ++ + T G + L C+ G+ P I W ++ QP
Sbjct: 2744 AMGKTRLV-VQVPPVIENGLPDLSTTEGSHAFLPCKARGS-PEPNITWDKD-GQPVSGAE 2800
Query: 352 -EVIIQPSSRHLITQ-DGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSV 405
+ IQPS L+ +GQ D G Y C A++ VG + L++
Sbjct: 2801 GKFTIQPSGELLVKNLEGQ-------------DAGTYTCTAENAVGRARRRVHLTI 2843
Score = 57.4 bits (137), Expect = 3e-08
Identities = 67/274 (24%), Positives = 109/274 (39%), Gaps = 25/274 (9%)
Query: 143 AARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISPNLQGNYTCL 202
A +V C +S P P + W + LN ++ L + SP GNY C+
Sbjct: 2677 AVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCI 2736
Query: 203 ALNQLSKRHRKVTTELLVYYPPP---SAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWI 259
A N K T L+V PP P S +F L C+ G P+P+ W
Sbjct: 2737 AKNSAGSAMGK--TRLVVQVPPVIENGLPDLSTTEGSHAF---LPCKARGS-PEPNITWD 2790
Query: 260 EEPGGVIVGKSKLGVE-----MLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSLL 314
++ V + K ++ ++ + D + C + VG + + P
Sbjct: 2791 KDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLPVFT 2850
Query: 315 SEPM-KTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLT 373
+ P ++ G + L C G+ P +I W N +P + + QDG STL
Sbjct: 2851 TLPGDRSLRLGDRLWLRCAARGS-PTPRIGWTVN-------DRPVTEGVSEQDG-GSTLQ 2901
Query: 374 IHNCSQDLDEGYYICRADSPVGVREMEIWLSVKE 407
S++ D G Y+C A++ VG + ++ VKE
Sbjct: 2902 RAAVSRE-DSGTYVCWAENRVGRTQAVSFVHVKE 2934
Score = 56.2 bits (134), Expect = 7e-08
Identities = 90/409 (22%), Positives = 146/409 (35%), Gaps = 59/409 (14%)
Query: 26 VGLEAVVIGEVHENVTLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSL--- 82
+G E V +E+V L C + + ++W+++ RP EPR +
Sbjct: 792 LGEELNVSVVANESVALECQSHAMPPPVLSWWKDG-------------RPLEPRPGVHLS 838
Query: 83 VDATSLHIESLSLGDEGIYTCQEILNVTQWFQVWLQVASGPYQIEVHIVATGTLPNG-TL 141
D L ++ + D G YTC+ + + Y + V + L TL
Sbjct: 839 ADKALLQVDRADVWDAGHYTCEALNQAGH--------SEKHYNLNVWVAPVFPLRESHTL 890
Query: 142 YAARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISPNL---QGN 198
G SC P P + W E G LL + +G
Sbjct: 891 TVREGHPTRLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGT 950
Query: 199 YTCLALNQLSKRHRKVTTELLVYYPP----PSAPQCWAQMASGSFMLQLTCRWDGGYPDP 254
YTC N + + + E V+ PP P P + + L C G P P
Sbjct: 951 YTCECSNVVGNSSQDLQLE--VHVPPQIAGPREPPTQVSVVQDG-VATLECNATGK-PPP 1006
Query: 255 DFLWIEEPGGVIVGKSKLGVEMLSE--------SQLSDGKKFKCVTSHIVGPESGASCMV 306
W E G VG ++LG+++ ++ +Q + ++ CV ++ G +
Sbjct: 1007 TVTW--ERDGQPVG-AELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGRAERKFELS 1063
Query: 307 QIRGPSLLSE--PMK--TCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHL 362
+ P L+ + P+ T +TL C+ G PPA I W R E + P
Sbjct: 1064 VLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPA-IRWFRG----EEPVSPGEDTY 1118
Query: 363 ITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEPLNI 411
+ G +T +Q+ D G Y C A + G + V P +I
Sbjct: 1119 LLAGGWMLKMTQ---TQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSI 1164
Score = 55.5 bits (132), Expect = 1e-07
Identities = 86/375 (22%), Positives = 136/375 (36%), Gaps = 43/375 (11%)
Query: 36 VHENVTLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSLVDATSLHIESLSL 95
++ +V+L C + +VTWY+++ +L E F L +L + L
Sbjct: 1669 LNSSVSLPCDVHAHPNPEVTWYKDSQ----------ALSLGEEVFLLPGTHTLQLGRARL 1718
Query: 96 GDEGIYTCQEILNVTQWFQVWLQVASGPYQIEVHIVATGTLPNGTLYAARGSQVDFSCNS 155
D G+YTC E LN Q +Q++ + P + G + SC +
Sbjct: 1719 SDSGMYTC-EALNAAGRDQKLVQLS---VLVPPAFRQAPRGPQDAVLVRVGDKAVLSCET 1774
Query: 156 SSRPPPVVEWW------FQALNSSSESFGHNLTVNFFSLLLISPNLQGNYTCLALNQLSK 209
+ P P V W+ A + + G L + + + +G Y+C N +
Sbjct: 1775 DALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQV-----SDKGLYSCKVSNVAGE 1829
Query: 210 RHRKVTTELLVYYPPP-SAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWIE-----EPG 263
R T L V PP P+ L LTC G P P W++ E
Sbjct: 1830 AVRTFT--LTVQVPPTFENPKTETVSQVAGSPLVLTCD-VSGVPAPTVTWLKDRMPVESS 1886
Query: 264 GVIVGKSKLGVEMLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSLLSEPMKT--- 320
V S+ G LS Q + + CV + + + P + S +
Sbjct: 1887 AVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHH 1946
Query: 321 CFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQD 380
G V L C+ G PP + WL++ + + P R + DG + L S
Sbjct: 1947 VLEGQEVRLDCEADG-QPPPDVAWLKDGSPLGQDMGPHLRFYL--DGGSLVLKGLRAS-- 2001
Query: 381 LDEGYYICRADSPVG 395
D G Y C A +P G
Sbjct: 2002 -DAGAYTCVAHNPAG 2015
Score = 54.3 bits (129), Expect = 3e-07
Identities = 59/232 (25%), Positives = 92/232 (39%), Gaps = 24/232 (10%)
Query: 197 GNYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASG--SFMLQLTCRWDGGYPDP 254
G Y+C A NQ R LLV PP AQ G ++L C W G P P
Sbjct: 100 GLYSCRAENQAGTAQRDF--HLLVLTPPSVLGAGAAQEVLGLAGADVELQC-WTSGVPTP 156
Query: 255 DFLWIEEPGGVIVGKSKLGVE------MLSESQLSDGKKFKCVTSHIVGPESGASCMVQI 308
W ++ V+ G L V+ ++ S + D +++CV G ++ +++
Sbjct: 157 QVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQCVAFSPAGQQA-RDFQLRV 215
Query: 309 RGPSLLSEPMKT----CFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLIT 364
P + +T V L C+ G P I W ++ ++ S++ + T
Sbjct: 216 HAPPTIWGSNETGEVAVMEDHLVQLLCEARGV-PTPNITWFKD----GALLPTSTKVVYT 270
Query: 365 QDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEPLNIGGIVG 416
+ G+ L +Q D G Y C+A + VG E L V P I G G
Sbjct: 271 RGGRQLQL---GRAQSSDAGVYTCKASNAVGAAEKATRLDVYVPPTIEGAGG 319
Score = 54.3 bits (129), Expect = 3e-07
Identities = 83/361 (22%), Positives = 127/361 (35%), Gaps = 62/361 (17%)
Query: 84 DATSLHIESLSLGDEGIYTCQEILNVTQWFQVWLQVASGP-------YQIEVHI-----V 131
D + L +ES G+Y+C VAS P Y +EV + V
Sbjct: 366 DGSVLRLESPGEASSGLYSC---------------VASSPAGEAVLQYSVEVQVPPQLLV 410
Query: 132 ATGTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLL- 190
A G G + G ++ C +S P P ++ W Q + E G + +L +
Sbjct: 411 AEGL---GQVTTIVGQPLELPCQASGSPVPTIQ-WLQNGRPAEELAGVQVASQGTTLHID 466
Query: 191 -ISPNLQGNYTCLALNQLSKRHRKVTTELLVYYPP-----PSAPQCWAQMASGSFMLQL- 243
+ + G + C A N+ +V + + P P W SF
Sbjct: 467 HVELDHSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLEVPIGQYHWGXEHHSSFPAACD 526
Query: 244 --TCRWDGGYPDPDF---------LWIEEPGGVIVGKSKLGVEMLSESQLSDGKKFKCVT 292
R G +P P LW EP G+ V S + + L D + C
Sbjct: 527 PPVHRGWGAHPKPPLVEGWCSPGSLW-GEPTGIPVAYSLPPPLQIEKVDLRDEGIYTCAA 585
Query: 293 SHIVGPESGASCMVQIRGPSLLSEPM-KTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQP 351
+++ G + + P++ P+ K +VTL C SG PP + W +
Sbjct: 586 TNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLECLASGV-PPPDVSWFKG---- 640
Query: 352 EVIIQPSSRHL-ITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEPLN 410
QP S + +T L I +Q D G Y C A + G E+ L V P
Sbjct: 641 ---HQPVSSWMGVTVSVDGRVLRIEQ-AQLSDAGSYRCVASNVAGSTELRYGLRVNVPPR 696
Query: 411 I 411
I
Sbjct: 697 I 697
Score = 52.4 bits (124), Expect = 1e-06
Identities = 89/377 (23%), Positives = 147/377 (38%), Gaps = 56/377 (14%)
Query: 41 TLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSLVD-ATSLHIESLSLGDEG 99
TL C VTW R+ +PV AE L + SLH+E G
Sbjct: 995 TLECNATGKPPPTVTWERDG-QPV----------GAELGLQLQNQGQSLHVERAQAAHTG 1043
Query: 100 IYTC-QEILNVTQWFQVWLQVASGPYQIEVHIVATGTL-PNGTLYAARGSQVDFSCNSSS 157
Y+C E L + L V P I G L P + AA S + C +
Sbjct: 1044 RYSCVAENLAGRAERKFELSVLVPPELI-------GDLDPLTNITAALHSPLTLLCEAMG 1096
Query: 158 RPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISPNLQ--GNYTCLALNQLSKRHRKVT 215
PPP + WF+ S L + L + Q G Y+CLA N+ + R +
Sbjct: 1097 IPPPAIR-WFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFS 1155
Query: 216 TELLVYYPPPSAPQCWAQM------ASGSFMLQLTCRWDGGYPDPDFLWIEEPGGVIVGK 269
E+LV PP + ++ + M +T G+P P W ++ + G
Sbjct: 1156 VEVLV--PPSIENEDLEEVIKVLDGQTAHLMCNVT-----GHPQPKLTWFKDGRPLARGD 1208
Query: 270 ----SKLGVEM-LSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSLL------SEPM 318
S GV + + ++ LS + C+ ++ VG ++ + + P++L ++
Sbjct: 1209 AHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEE 1268
Query: 319 KTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCS 378
T ++L C+ A+P I W+++ E +SR++ G + L I N
Sbjct: 1269 VTVTVNNPISLICEAL-AFPSPNITWMKDGAPFE-----ASRNIQLLPGTHG-LQILNAQ 1321
Query: 379 QDLDEGYYICRADSPVG 395
++ D G Y C + +G
Sbjct: 1322 KE-DAGQYTCVVTNELG 1337
Score = 52.4 bits (124), Expect = 1e-06
Identities = 93/389 (23%), Positives = 139/389 (35%), Gaps = 51/389 (13%)
Query: 28 LEAVVIGEVHENVTLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSLVDATS 87
L +VV E V L C R +TW + +S+ ++
Sbjct: 2671 LPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQ-----------VLPGGQ 2719
Query: 88 LHIESLSLGDEGIYTCQEILNVTQWFQVWLQVASGPYQIEVHI--VATGTLPNGTLYAAR 145
L I S D G Y C + A G ++ V + V LP+ L
Sbjct: 2720 LRIAHASPEDAGNYLCIAKNSAGS--------AMGKTRLVVQVPPVIENGLPD--LSTTE 2769
Query: 146 GSQVDFSCNSSSRPPPVVEWWF--QALNSSSESFGHNLTVNFFSLLLISPNLQGN----Y 199
GS C + P P + W Q ++ + F T+ LL+ NL+G Y
Sbjct: 2770 GSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKF----TIQPSGELLVK-NLEGQDAGTY 2824
Query: 200 TCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWI 259
TC A N + + R+V +LV + P + L+ R G P P W
Sbjct: 2825 TCTAENAVGRARRRVHLTILVLPVFTTLPGDRSLRLGDRLWLRCAAR---GSPTPRIGWT 2881
Query: 260 EEPGGVIVGKSKL-GVEMLSESQLS--DGKKFKCVTSHIVGPESGASCMVQIRGPSLLSE 316
V G S+ G L + +S D + C + VG S + P L E
Sbjct: 2882 VNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQGE 2941
Query: 317 PMKTCF--TGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTI 374
GG++ L C V G P I W+++ P + QN +LTI
Sbjct: 2942 AFSYLVEPVGGSIQLDCVVRGD-PVPDIHWIKDGL-------PLRGSHLRHQLQNGSLTI 2993
Query: 375 HNCSQDLDEGYYICRADSPVGVREMEIWL 403
+D D G Y C A++ +GV + + L
Sbjct: 2994 RRTERD-DAGRYQCLAENEMGVAKKVVIL 3021
Score = 51.6 bits (122), Expect = 2e-06
Identities = 78/352 (22%), Positives = 133/352 (37%), Gaps = 54/352 (15%)
Query: 82 LVDATSLHIESLSLGDEGIYTCQEILNVTQWFQVWLQVASGPYQIEVHIV------ATGT 135
L + SLH + GD G+Y+C+ + +G Q + H++ G
Sbjct: 83 LDEGQSLHFPRIQEGDSGLYSCR------------AENQAGTAQRDFHLLVLTPPSVLGA 130
Query: 136 LPNGTLYAARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISPNL 195
+ G+ V+ C +S P P VEW G +L V +L
Sbjct: 131 GAAQEVLGLAGADVELQCWTSGVPTPQVEWTKD--RQPVLPGGPHLQVQEDGQVLRITGS 188
Query: 196 ----QGNYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASG------SFMLQLTC 245
+G Y C+A + ++ R +L V+ P P W +G ++QL C
Sbjct: 189 HVGDEGRYQCVAFSPAGQQARDF--QLRVHAP----PTIWGSNETGEVAVMEDHLVQLLC 242
Query: 246 RWDGGYPDPDFLWIEE----PGGVIVGKSKLGVEM-LSESQLSDGKKFKCVTSHIVGPES 300
G P P+ W ++ P V ++ G ++ L +Q SD + C S+ VG
Sbjct: 243 E-ARGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAE 301
Query: 301 GASCMVQIRGPSLLSEP----MKTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQ 356
A+ + P++ + G V L C V+ +P + W + +
Sbjct: 302 KATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALEC-VARGHPSPTLSW----HHEGLPVA 356
Query: 357 PSSRHLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEP 408
S+ + DG S L + + + G Y C A SP G ++ + V+ P
Sbjct: 357 ESNESRLETDG--SVLRLES-PGEASSGLYSCVASSPAGEAVLQYSVEVQVP 405
Score = 50.1 bits (118), Expect = 5e-06
Identities = 98/489 (20%), Positives = 176/489 (35%), Gaps = 86/489 (17%)
Query: 2 AAGGSAPEPRVLVCLGALLAGWVAVGLEAVVIGEVHENVTLHCGNISGLRGQVTWYRNNS 61
A G ++ V L + G + V V+ ++L C ++ +TW ++ +
Sbjct: 1239 AVGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMKDGA 1298
Query: 62 EPVFLLSSNSSLRPAEPRFSLVDATSLHIESLSLGDEGIYTC---QEILNVTQWFQVWL- 117
F S N L P +++A D G YTC E+ + + V +
Sbjct: 1299 P--FEASRNIQLLPGTHGLQILNAQK--------EDAGQYTCVVTNELGEAVKNYHVEVL 1348
Query: 118 ---QVASGPYQIEVHIVATGTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWWFQALNSSS 174
++ EV + T N TL C S + PPP + W+ +
Sbjct: 1349 IPPSISKDDPLAEVGVKEVKTKVNSTL--------TLECESWAVPPPTIRWYKDGQPVTP 1400
Query: 175 ESFGHNLTVNFFSLLLISPNL---QGNYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCW 231
S + LL I P G Y C+A N + + +L+ PP +
Sbjct: 1401 SS--RLQVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDF--NVLIQVPP-----MF 1451
Query: 232 AQMASGSFMLQLTCRWD---GG---------------------YPDPDFLWIEEPG---- 263
++ S ++ R + GG P PD W E
Sbjct: 1452 QKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWYREDQPLSA 1511
Query: 264 ----GVIVGKSKLGVEMLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSLLSEPMK 319
V+ G L + ++ + + ++ C S+ VG + ++ + P +L + +
Sbjct: 1512 GDEVSVLQGGRVLQIPLV---RAENAGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEE 1568
Query: 320 -----TCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTI 374
T V+L C G P I WL+N + PS R + +DGQ +
Sbjct: 1569 LVEEVTVNASSTVSLQCPALG-NPVPTISWLQN----GLPFSPSPRLQVLEDGQVLQV-- 1621
Query: 375 HNCSQDLDEGYYICRADSPVGVREMEIWLSVKEPLNIGGI-VGTIVSLLLLGLAIISGLL 433
+ ++ D Y+C A++ G E L V+ P I G+ + + ++L +++ +
Sbjct: 1622 -STAEVADAASYMCVAENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVH 1680
Query: 434 LHYSPVFCW 442
H +P W
Sbjct: 1681 AHPNPEVTW 1689
Score = 49.3 bits (116), Expect = 9e-06
Identities = 83/354 (23%), Positives = 126/354 (35%), Gaps = 62/354 (17%)
Query: 83 VDATSLHIESLSLGDEGIYTCQEILNVTQWFQVWLQVASGP-------YQIEVHIVAT-- 133
+D SL ++ L D G YTC VA P + + V + T
Sbjct: 1988 LDGGSLVLKGLRASDAGAYTC---------------VAHNPAGEDARLHTVNVLVPPTIK 2032
Query: 134 -GTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWWFQAL------NSSSESFGHNLTVNFF 186
G +GTL + G V C PP V W L + GH L ++
Sbjct: 2033 QGADGSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKV 2092
Query: 187 SLLLISPNLQGNYTCLALNQLSKRHRKVTTELLVYYPPPSAP---QCWAQMASGSFMLQL 243
L G +TC+A + R T ++ V PP P Q + GS +++L
Sbjct: 2093 QLADA-----GIFTCVAASPAGVADRNFTLQVQV--PPVLEPVEFQNDVVVVRGS-LVEL 2144
Query: 244 TCRWDGGYPDPDFLWIEEPGGVIVGKSKLGVEMLSESQ-LSDGKKFKCVTSHIVGPESGA 302
C G P P W+++ ++ + G + E+ D + CV G
Sbjct: 2145 PCE-ARGVPLPLVSWMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRH 2203
Query: 303 SCMVQIRGPSL--LSEPMKTCFT-GGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSS 359
+ + P + +P + T G + L C G P I W ++
Sbjct: 2204 FQLTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGT-PQPNITWHKD------------ 2250
Query: 360 RHLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEPLNIGG 413
+T+ NS T + D G Y C A+SP G E + V+ P NI G
Sbjct: 2251 GQALTRLENNSRAT--RVLRVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVG 2302
Score = 45.4 bits (106), Expect = 1e-04
Identities = 89/407 (21%), Positives = 153/407 (37%), Gaps = 63/407 (15%)
Query: 35 EVHENVTLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSLVDATSLHIESLS 94
+V+ +TL C + + + WY++ +PV P+ L + L I+
Sbjct: 1370 KVNSTLTLECESWAVPPPTIRWYKDG-QPV---------TPSSRLQVLGEGRLLQIQPTQ 1419
Query: 95 LGDEGIYTCQEILNVT----QWFQVWLQVAS-----GPYQIEVHIVATGTLPNGTLYAAR 145
+ D G Y C NV Q F V +QV G + I++ G + R
Sbjct: 1420 VSDSGRYLCVAT-NVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYR 1478
Query: 146 ----GSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTV----NFFSLLLISPNLQG 197
+ C++++ PPP + W+ + S G ++V + L+ G
Sbjct: 1479 EIVENNPAYLYCDTNAIPPPDLTWYRE---DQPLSAGDEVSVLQGGRVLQIPLVRAENAG 1535
Query: 198 NYTCLALNQLSKRHRKVTTELLVYYPP----PSAPQCWAQMASGSFMLQLTCRWDGGYPD 253
Y+C A N++ + + ELLV PP + + S + L C G P
Sbjct: 1536 RYSCKASNEVGEDW--LHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALGN-PV 1592
Query: 254 PDFLWIE-----EPGGVIVGKSKLGVEMLSESQLSDGKKFKCVTSHIVG-PESGASCMVQ 307
P W++ P + V +S ++++D + CV + G E + VQ
Sbjct: 1593 PTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGSAEKLFTLRVQ 1652
Query: 308 IRGPSL--LSEPMKTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQ----PEVIIQPSSRH 361
+ P + L T +V+L C V A+P ++ W ++ EV + P +
Sbjct: 1653 V-PPRIAGLDLEQVTAILNSSVSLPCDVH-AHPNPEVTWYKDSQALSLGEEVFLLPGTHT 1710
Query: 362 LITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEP 408
L + S D G Y C A + G + + LSV P
Sbjct: 1711 LQLGRARLS-----------DSGMYTCEALNAAGRDQKLVQLSVLVP 1746
Score = 44.7 bits (104), Expect = 2e-04
Identities = 82/349 (23%), Positives = 127/349 (36%), Gaps = 37/349 (10%)
Query: 73 LRPAEPRFSLVDATSLHIESLSLGDEGIYTCQEILNVTQWFQVW-LQVASGPYQIEVHIV 131
L P PRF ++ SL I+ + D G Y C + Q L+V P
Sbjct: 2431 LDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEPP-------- 2482
Query: 132 ATGTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWW--FQALNSSSESFGHNLTVNFFSLL 189
A P+ A + C +S P P+V WW Q L+ + + L + +LL
Sbjct: 2483 AIAPSPSNLTLTAHTPAL-LPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPS-NALL 2540
Query: 190 LISPNLQ--GNYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRW 247
L +P Q + C+ N++ + HR ++ V+ PP A + + LTC
Sbjct: 2541 LTAPGPQDSAQFECVVSNEVGEAHR--LYQVTVHVPPTIADDQTDFTVTMMAPVVLTCH- 2597
Query: 248 DGGYPDPDFLWIEEPGGVIVGKSKLGVEMLSESQLSDGK-------KFKCVTSHIVGPES 300
G P P W G +G G + L G+ ++ C + G
Sbjct: 2598 STGIPAPTVSW--SKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAGVAH 2655
Query: 301 GASCMVQIRGPSLLSEP-MKTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSS 359
+ P + P + V L C+ SG P I W Q E + +
Sbjct: 2656 KHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASG-IPRPTITW-----QKEGLNVATG 2709
Query: 360 RHLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEP 408
+ TQ L I + S + D G Y+C A + G + L V+ P
Sbjct: 2710 --VSTQVLPGGQLRIAHASPE-DAGNYLCIAKNSAGSAMGKTRLVVQVP 2755
Score = 44.3 bits (103), Expect = 3e-04
Identities = 68/290 (23%), Positives = 115/290 (39%), Gaps = 41/290 (14%)
Query: 142 YAARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISPNLQ----G 197
+ G +V C + +PPP V W + + + G +L L+ L+ G
Sbjct: 1946 HVLEGQEVRLDCEADGQPPPDVA-WLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAG 2004
Query: 198 NYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSF------MLQLTCRWDGGY 251
YTC+A N + R T +LV PP+ Q SG+ ++ + C G
Sbjct: 2005 AYTCVAHNPAGEDARLHTVNVLV---PPTIKQ--GADGSGTLVSRPGELVTMVCPVRGS- 2058
Query: 252 PDPDFLWIEEPGGVIVGKSKL-----GVEMLSESQLSDGKKFKCVTSHIVGPESGASCMV 306
P W+++ + + + L +S+ QL+D F CV + G + + +
Sbjct: 2059 PPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAG-VADRNFTL 2117
Query: 307 QIRGPSLLSEPMK-----TCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRH 361
Q++ P +L EP++ G V L C+ G P + W+++ E ++ S
Sbjct: 2118 QVQVPPVL-EPVEFQNDVVVVRGSLVELPCEARGV-PLPLVSWMKD---GEPLLSQS--- 2169
Query: 362 LITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEPLNI 411
+ G + L D G Y C A S G L+V EP +I
Sbjct: 2170 --LEQGPSLQLEAVGAG---DSGTYSCVAVSEAGEARRHFQLTVMEPPHI 2214
Score = 43.9 bits (102), Expect = 4e-04
Identities = 86/361 (23%), Positives = 135/361 (37%), Gaps = 59/361 (16%)
Query: 71 SSLRPAEPRFS--LVDATSLHIESLSLGDEGIYTC---QEILNVTQWFQVWLQVASGPYQ 125
S ++ EP S L SL +E++ GD G Y+C E + FQ L V P
Sbjct: 2157 SWMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQ--LTVMEPP-- 2212
Query: 126 IEVHIVATGTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWW--FQALNSSSESFGHNLTV 183
HI +G L G+ ++ C++ P P + W QAL L
Sbjct: 2213 ---HIEDSGQPTE--LSLTPGAPMELLCDAQGTPQPNITWHKDGQALT--------RLEN 2259
Query: 184 NFFSLLLISPNLQGNYTCLALNQLSKRHRKVTTELLVYYPP----PSAPQCWAQMASGSF 239
N + ++ G YTCLA + + + + V PP P P+ +A G
Sbjct: 2260 NSRATRVLRVRDAGLYTCLAESPAGAIEK--SFRVRVQAPPNIVGPRGPRFVVGLAPGQL 2317
Query: 240 MLQLTCRWDGGYPDPDFLWIEEPGGVIVGKSK----------LGVEMLSESQLSDGKKFK 289
+L+ + + P P W + G+++ + L ++ LS + D +
Sbjct: 2318 VLECSVEAE---PAPKITWHRD--GIVLQEDAHTQFPERGRFLQLQALSTADSGD---YS 2369
Query: 290 CVTSHIVGPESGASCMVQIRGPSLLS-EPMKTCFTGGNVTLTCQVSGAYPPAKILWLRNL 348
C + G S A + P++ S P L CQ G P + W ++
Sbjct: 2370 CTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGV-PAPLVSWRKD- 2427
Query: 349 TQPEVIIQP-SSRHLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKE 407
V + P S R I +G +L I D G+Y+C A + G L V E
Sbjct: 2428 ---RVPLDPRSPRFEILPEG---SLRIQPVLAQ-DAGHYLCLASNSAGSDRQGRDLRVLE 2480
Query: 408 P 408
P
Sbjct: 2481 P 2481
Score = 35.8 bits (81), Expect = 0.10
Identities = 80/363 (22%), Positives = 134/363 (36%), Gaps = 63/363 (17%)
Query: 197 GNYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASG--------SFMLQLTCRWD 248
G YTC+ N+L + + E+L+ PPS + G + L L C
Sbjct: 1326 GQYTCVVTNELGEAVKNYHVEVLI---PPSISKDDPLAEVGVKEVKTKVNSTLTLECE-S 1381
Query: 249 GGYPDPDFLWIEEPGGVIVGKSKLGV------EMLSESQLSDGKKFKCVTSHIVGPESGA 302
P P W ++ G + S+L V + +Q+SD ++ CV +++ G E
Sbjct: 1382 WAVPPPTIRWYKD-GQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVATNVAG-EDDQ 1439
Query: 303 SCMVQIRGPSLLSE--PMKTCF--------TGGNVT------------LTCQVSGAYPPA 340
V I+ P + + F G VT L C + A PP
Sbjct: 1440 DFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYCD-TNAIPPP 1498
Query: 341 KILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREME 400
+ W R QP + + Q G+ + + + G Y C+A + VG +
Sbjct: 1499 DLTWYRE-DQP---LSAGDEVSVLQGGRVLQIPLVRAE---NAGRYSCKASNEVGEDWLH 1551
Query: 401 IWLSVKEPLNIGGIVGTIVSLLLLGLAIISGL----LLHYSPVFCW-----KVGNTSRGQ 451
L V P I G +V + + + L L + P W + R Q
Sbjct: 1552 YELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQ 1611
Query: 452 NMDDVMVLVDSEEEEEEEEE---EEEDAAVGEQEGAREREELPKEIPKQDHIHRVTALVN 508
++D VL S E + E+ A ++ R ++P I D + +VTA++N
Sbjct: 1612 VLEDGQVLQVSTAEVADAASYMCVAENQAGSAEKLFTLRVQVPPRIAGLD-LEQVTAILN 1670
Query: 509 GNI 511
++
Sbjct: 1671 SSV 1673
Score = 32.3 bits (72), Expect = 1.1
Identities = 29/115 (25%), Positives = 51/115 (44%), Gaps = 18/115 (15%)
Query: 324 GGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSR-----------HLITQDGQNSTL 372
G ++TL C +G +P +I+WL++ V + + H + +GQ+
Sbjct: 33 GQSLTLECDANG-FPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHF 91
Query: 373 TIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEPLNIGGIVGTIVSLLLLGLA 427
Q+ D G Y CRA++ G + + L V P ++G + +LGLA
Sbjct: 92 PR---IQEGDSGLYSCRAENQAGTAQRDFHLLVLTP---PSVLGAGAAQEVLGLA 140
Score = 31.6 bits (70), Expect = 1.9
Identities = 37/170 (21%), Positives = 62/170 (36%), Gaps = 10/170 (5%)
Query: 146 GSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISPNLQGNYTCLALN 205
G + C P P + W L H L ++ + G Y CLA N
Sbjct: 2951 GGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIRRTERDDAGRYQCLAEN 3010
Query: 206 QLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWIEEPGGV 265
++ +KV +L P + SG + L C+ G P P W+ + G
Sbjct: 3011 EMGVA-KKVVILVLQSAPVFQVEPQDMTVRSGD-DVALRCQ-ATGEPTPTIEWL-QAGQP 3066
Query: 266 IVGKSKL-----GVEMLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRG 310
+ +L G L + D + CV +++G + + +V +RG
Sbjct: 3067 LRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNLLGSATARAFLV-VRG 3115
>gi|7657359 contactin 5 isoform long [Homo sapiens]
Length = 1100
Score = 67.0 bits (162), Expect = 4e-11
Identities = 95/359 (26%), Positives = 148/359 (41%), Gaps = 55/359 (15%)
Query: 79 RFSLVDATSLHIESLSLGDEGIYTC--------QEILNVTQWFQVWLQVASGPYQ--IEV 128
RF + +L+I + D G Y C +L+ + G Y+ IEV
Sbjct: 245 RFISQETGNLYISKVQTSDVGSYICLVKNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEV 304
Query: 129 HIVATGTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSL 188
H T T AA+G+ V C + P P + W +N S +
Sbjct: 305 HFPFTVT-------AAKGTTVKMECFALGNPVPTITW--MKVNGYIPS---KARLRKSQA 352
Query: 189 LLISPNLQ----GNYTCLALNQLSKRHRKVTTELLVY-YPPPSAPQCWAQMASGSFMLQL 243
+L PN+Q G Y C A N K + +L VY YP Q+ SGS +
Sbjct: 353 VLEIPNVQLDDAGIYECRAENSRGKNSFR--GQLQVYTYPHWVEKLNDTQLDSGSPL--- 407
Query: 244 TCRWD---GGYPDPDFLWIEEPGGVIVGKSKL----GVEMLSESQLSDGKKFKCVTSHIV 296
RW+ G P P + W++ G + +S++ GV M+ SD ++C+ +
Sbjct: 408 --RWECKATGKPRPTYRWLKN-GVPLSPQSRVEMVNGVLMIHNVNQSDAGMYQCLAENKY 464
Query: 297 GP-ESGASCMVQIRGPSL-LSEPMKTCFTGGN--VTLTCQVSGAYPPAKILWLRNLTQPE 352
G + A + P+ L++ KT + V + C+ G+ P I W + +
Sbjct: 465 GAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGS-PKPTISWKKG----D 519
Query: 353 VIIQPSSRHLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEPLNI 411
++ + R I DG +L I N S+ DEG Y+CR ++ G E+ LSVKEP I
Sbjct: 520 RAVRENKRIAILPDG---SLRILNASKS-DEGKYVCRGENVFGSAEIIASLSVKEPTRI 574
Score = 38.5 bits (88), Expect = 0.016
Identities = 83/379 (21%), Positives = 133/379 (35%), Gaps = 51/379 (13%)
Query: 38 ENVTLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSLVDATSLHIESLSLGD 97
+ V L+C W RN +E ++ R+SL+D T + D
Sbjct: 117 KKVALNCEVRGNPVPSYRWLRNGTEIDL---------ESDYRYSLIDGTFIISNPSEAKD 167
Query: 98 EGIYTCQEILNVTQWF--QVWLQVASGPYQIEVHIVATGTLPNGTLYAARGSQVDFSCNS 155
G Y C V + LQ A ++ + G V C+
Sbjct: 168 SGHYQCLATNTVGSILSREATLQFA--------YLGNFSGRTRSAVSVREGQGVVLMCSP 219
Query: 156 SSRPPPVV-EWWFQALNS----SSESFGHNLTVNFFSLLLISPNLQGNYTCLALNQLSK- 209
P ++ W F S S F T N + + + + G+Y CL N ++
Sbjct: 220 PPHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLY-ISKVQTSDVGSYICLVKNTVTNA 278
Query: 210 RHRKVTTELLV--------YYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWIEE 261
R T L + Y P + A+ +++ C + G P P W+ +
Sbjct: 279 RVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMEC-FALGNPVPTITWM-K 336
Query: 262 PGGVIVGKSKL----GVEMLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSLLSEP 317
G I K++L V + QL D ++C + G S + P + +
Sbjct: 337 VNGYIPSKARLRKSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYPHWVEKL 396
Query: 318 MKTCFTGGN-VTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHN 376
T G+ + C+ +G P WL+N V + P SR + N L IHN
Sbjct: 397 NDTQLDSGSPLRWECKATGK-PRPTYRWLKN----GVPLSPQSR----VEMVNGVLMIHN 447
Query: 377 CSQDLDEGYYICRADSPVG 395
+Q D G Y C A++ G
Sbjct: 448 VNQS-DAGMYQCLAENKYG 465
Score = 36.6 bits (83), Expect = 0.060
Identities = 29/90 (32%), Positives = 41/90 (45%), Gaps = 11/90 (12%)
Query: 310 GPSLLSEPMKTCFTGGN----VTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQ 365
GP + EP F + V L C+V G P WLRN T E+ ++ R+ +
Sbjct: 98 GPVFVQEPDDIIFPTDSDEKKVALNCEVRGN-PVPSYRWLRNGT--EIDLESDYRYSLI- 153
Query: 366 DGQNSTLTIHNCSQDLDEGYYICRADSPVG 395
+ T I N S+ D G+Y C A + VG
Sbjct: 154 ---DGTFIISNPSEAKDSGHYQCLATNTVG 180
>gi|28373129 contactin 5 isoform short [Homo sapiens]
Length = 1026
Score = 67.0 bits (162), Expect = 4e-11
Identities = 95/359 (26%), Positives = 148/359 (41%), Gaps = 55/359 (15%)
Query: 79 RFSLVDATSLHIESLSLGDEGIYTC--------QEILNVTQWFQVWLQVASGPYQ--IEV 128
RF + +L+I + D G Y C +L+ + G Y+ IEV
Sbjct: 171 RFISQETGNLYISKVQTSDVGSYICLVKNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEV 230
Query: 129 HIVATGTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSL 188
H T T AA+G+ V C + P P + W +N S +
Sbjct: 231 HFPFTVT-------AAKGTTVKMECFALGNPVPTITW--MKVNGYIPS---KARLRKSQA 278
Query: 189 LLISPNLQ----GNYTCLALNQLSKRHRKVTTELLVY-YPPPSAPQCWAQMASGSFMLQL 243
+L PN+Q G Y C A N K + +L VY YP Q+ SGS +
Sbjct: 279 VLEIPNVQLDDAGIYECRAENSRGKNSFR--GQLQVYTYPHWVEKLNDTQLDSGSPL--- 333
Query: 244 TCRWD---GGYPDPDFLWIEEPGGVIVGKSKL----GVEMLSESQLSDGKKFKCVTSHIV 296
RW+ G P P + W++ G + +S++ GV M+ SD ++C+ +
Sbjct: 334 --RWECKATGKPRPTYRWLKN-GVPLSPQSRVEMVNGVLMIHNVNQSDAGMYQCLAENKY 390
Query: 297 GP-ESGASCMVQIRGPSL-LSEPMKTCFTGGN--VTLTCQVSGAYPPAKILWLRNLTQPE 352
G + A + P+ L++ KT + V + C+ G+ P I W + +
Sbjct: 391 GAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGS-PKPTISWKKG----D 445
Query: 353 VIIQPSSRHLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEPLNI 411
++ + R I DG +L I N S+ DEG Y+CR ++ G E+ LSVKEP I
Sbjct: 446 RAVRENKRIAILPDG---SLRILNASKS-DEGKYVCRGENVFGSAEIIASLSVKEPTRI 500
Score = 38.5 bits (88), Expect = 0.016
Identities = 83/379 (21%), Positives = 133/379 (35%), Gaps = 51/379 (13%)
Query: 38 ENVTLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSLVDATSLHIESLSLGD 97
+ V L+C W RN +E ++ R+SL+D T + D
Sbjct: 43 KKVALNCEVRGNPVPSYRWLRNGTEIDL---------ESDYRYSLIDGTFIISNPSEAKD 93
Query: 98 EGIYTCQEILNVTQWF--QVWLQVASGPYQIEVHIVATGTLPNGTLYAARGSQVDFSCNS 155
G Y C V + LQ A ++ + G V C+
Sbjct: 94 SGHYQCLATNTVGSILSREATLQFA--------YLGNFSGRTRSAVSVREGQGVVLMCSP 145
Query: 156 SSRPPPVV-EWWFQALNS----SSESFGHNLTVNFFSLLLISPNLQGNYTCLALNQLSK- 209
P ++ W F S S F T N + + + + G+Y CL N ++
Sbjct: 146 PPHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLY-ISKVQTSDVGSYICLVKNTVTNA 204
Query: 210 RHRKVTTELLV--------YYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWIEE 261
R T L + Y P + A+ +++ C + G P P W+ +
Sbjct: 205 RVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMEC-FALGNPVPTITWM-K 262
Query: 262 PGGVIVGKSKL----GVEMLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSLLSEP 317
G I K++L V + QL D ++C + G S + P + +
Sbjct: 263 VNGYIPSKARLRKSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYPHWVEKL 322
Query: 318 MKTCFTGGN-VTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHN 376
T G+ + C+ +G P WL+N V + P SR + N L IHN
Sbjct: 323 NDTQLDSGSPLRWECKATGK-PRPTYRWLKN----GVPLSPQSR----VEMVNGVLMIHN 373
Query: 377 CSQDLDEGYYICRADSPVG 395
+Q D G Y C A++ G
Sbjct: 374 VNQS-DAGMYQCLAENKYG 391
Score = 36.6 bits (83), Expect = 0.060
Identities = 29/90 (32%), Positives = 41/90 (45%), Gaps = 11/90 (12%)
Query: 310 GPSLLSEPMKTCFTGGN----VTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQ 365
GP + EP F + V L C+V G P WLRN T E+ ++ R+ +
Sbjct: 24 GPVFVQEPDDIIFPTDSDEKKVALNCEVRGN-PVPSYRWLRNGT--EIDLESDYRYSLI- 79
Query: 366 DGQNSTLTIHNCSQDLDEGYYICRADSPVG 395
+ T I N S+ D G+Y C A + VG
Sbjct: 80 ---DGTFIISNPSEAKDSGHYQCLATNTVG 106
>gi|33519481 neural cell adhesion molecule 2 precursor [Homo
sapiens]
Length = 837
Score = 65.9 bits (159), Expect = 9e-11
Identities = 84/389 (21%), Positives = 158/389 (40%), Gaps = 43/389 (11%)
Query: 38 ENVTLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSLVDATSLHIESLSLGD 97
E+ + C S V+W +N E V +S N RF+++ +L I +++ D
Sbjct: 130 EDAEVVCRVSSSPAPAVSWLYHNEE-VTTISDN--------RFAMLANNNLQILNINKSD 180
Query: 98 EGIYTCQEILNVTQWFQVWLQVASGPYQIEVHIVATGTLPNGTLYAA--RGSQVDFSCNS 155
EGIY C+ + ++ + V++ ++P + A RG ++ FSC +
Sbjct: 181 EGIYRCEGRVEARG------EIDFRDIIVIVNVPPAISMPQKSFNATAERGEEMTFSCRA 234
Query: 156 SSRPPPVVEWWFQA-LNSSSESFGHNLTVNFFSLLLISPNLQGNYTCLALNQLSKRHRKV 214
S P P + W+ L +E + + ++ I + G Y C A N+ + ++
Sbjct: 235 SGSPEPAISWFRNGKLIEENEKYILKGSNTELTVRNIINSDGGPYVCRATNKAGEDEKQA 294
Query: 215 TTELLVYYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWIEEPGGV--------- 265
++ V P Q + + + L C + G P P+ W G
Sbjct: 295 FLQVFV---QPHIIQLKNETTYENGQVTLVCDAE-GEPIPEITWKRAVDGFTFTEGDKSL 350
Query: 266 -----IVGKSKLGVEMLSESQLSDGKKFKC-VTSHIVGPESGASCMVQIRGPSLLSEPMK 319
+ G+ + + +LSD ++ C S I G + ++ + ++ +
Sbjct: 351 DGRIEVKGQHGSSSLHIKDVKLSDSGRYDCEAASRIGGHQKSMYLDIEYAPKFISNQTIY 410
Query: 320 TCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLIT-QDGQNSTLTIHNCS 378
+ G + ++C V + PPA I W R+ V+ ++ +L T G+ L I S
Sbjct: 411 YSWEGNPINISCDVK-SNPPASIHWRRDKL---VLPAKNTTNLKTYSTGRKMILEIAPTS 466
Query: 379 QDLDEGYYICRADSPVGVREMEIWLSVKE 407
D D G Y C A + +G R E L++ +
Sbjct: 467 -DNDFGRYNCTATNHIGTRFQEYILALAD 494
Score = 58.9 bits (141), Expect = 1e-08
Identities = 76/334 (22%), Positives = 130/334 (38%), Gaps = 28/334 (8%)
Query: 88 LHIESLSLGDEGIYTCQEILNVTQWFQVWLQVASGPYQIEVHIVATGTLPNGTLYAARGS 147
L I + ++ D GIY CQ Q +E++ T +G
Sbjct: 78 LTIYNANIEDAGIYRCQAT-------DAKGQTQEATVVLEIYQKLTFREVVSPQEFKQGE 130
Query: 148 QVDFSCNSSSRPPPVVEWWF--QALNSSSESFGHNLTVNFFSLLLISPNLQGNYTCLALN 205
+ C SS P P V W + + + + S++ L N +L I+ + +G Y C
Sbjct: 131 DAEVVCRVSSSPAPAVSWLYHNEEVTTISDNRFAMLANNNLQILNINKSDEGIYRCEGRV 190
Query: 206 QLSKRHRKVTTELLVYYPPP-SAPQ-CWAQMASGSFMLQLTCRWDGGYPDPDFLWIEEPG 263
+ ++V PP S PQ + A + +CR G P+P W
Sbjct: 191 EARGEIDFRDIIVIVNVPPAISMPQKSFNATAERGEEMTFSCRASGS-PEPAISWFR--N 247
Query: 264 GVIVGKSKLGVEMLSESQL-------SDGKKFKCVTSHIVGPESGASCMVQIRGPSLLSE 316
G ++ +++ + S ++L SDG + C ++ G + + + P ++
Sbjct: 248 GKLIEENEKYILKGSNTELTVRNIINSDGGPYVCRATNKAGEDEKQAFLQVFVQPHIIQL 307
Query: 317 PMKTCFTGGNVTLTCQVSGAYPPAKILWLR---NLTQPEVIIQPSSRHLITQDGQNSTLT 373
+T + G VTL C G P +I W R T E R I GQ+ + +
Sbjct: 308 KNETTYENGQVTLVCDAEGE-PIPEITWKRAVDGFTFTEGDKSLDGR--IEVKGQHGSSS 364
Query: 374 IHNCSQDL-DEGYYICRADSPVGVREMEIWLSVK 406
+H L D G Y C A S +G + ++L ++
Sbjct: 365 LHIKDVKLSDSGRYDCEAASRIGGHQKSMYLDIE 398
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 65.1 bits (157), Expect = 2e-10
Identities = 92/392 (23%), Positives = 157/392 (40%), Gaps = 48/392 (12%)
Query: 38 ENVTLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSLVDATSLHIESLSLG- 96
E+ C ++TW ++N E +RP + H+ L +G
Sbjct: 6286 ESADFECHVTGAQPMRITWSKDNKE----------IRPGGNYTITCVGNTPHLRILKVGK 6335
Query: 97 -DEGIYTCQEILNVTQ-WFQVWLQVASGPYQIEVHIVATGTLPNGTLYAARGSQVDFSCN 154
D G YTCQ +V + L V P ++ + A +G + C
Sbjct: 6336 GDSGQYTCQATNDVGKDMCSAQLSVKEPPKFVKKL--------EASKVAKQGESIQLECK 6387
Query: 155 SSSRPPPVVEWWFQALNSSSESFGHNLT-VNFFSLLLI---SPNLQGNYTCLALNQLSKR 210
S P V W F+ + ES+ +N++ +N +LL I S G+Y C A N +
Sbjct: 6388 ISGSPEIKVSW-FRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHNGVGDA 6446
Query: 211 HRKVTTELLVYYPP--PSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWIEEPGGVIVG 268
+T L V PP P + +LQ G P + +W+++ V
Sbjct: 6447 --SCSTALTVKAPPVFTQKPSPVGALKGSDVILQCEI---SGTPPFEVVWVKDRKQVRNS 6501
Query: 269 KS-KLGVEMLSES------QLSDGKKFKCVTSHIVGPESGASCMVQIRGPSLLSEPMKTC 321
K K+ + S + SD ++ C ++ VG ++ SC V+ + P + +
Sbjct: 6502 KKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVGSDT-CSCSVKFKEPPRFVKKLSDT 6560
Query: 322 FT--GGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQ 379
T G V L V G + P ++WL++ + +I+ S I+ +TL + + +
Sbjct: 6561 STLIGDAVELRAIVEG-FQPISVVWLKDRGE---VIRESENTRISFIDNIATLQLGS-PE 6615
Query: 380 DLDEGYYICRADSPVGVREMEIWLSVKEPLNI 411
+ G YIC+ + G+RE L+V EP I
Sbjct: 6616 ASNSGKYICQIKNDAGMRECSAVLTVLEPARI 6647
Score = 60.8 bits (146), Expect = 3e-09
Identities = 71/287 (24%), Positives = 112/287 (39%), Gaps = 30/287 (10%)
Query: 141 LYAARGSQVDFSCNSSSRPPPVVEWW-----FQALNSSSESFGHNLTVNFFSLLLISPNL 195
L AA G V C + P V W+ + F +N+ F+ + I N
Sbjct: 6088 LEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNI--ND 6145
Query: 196 QGNYTCLALNQLSKRHRKVTTELLVYYPPPS-APQCWAQMASGSFMLQLTCRWDGGYPDP 254
G YTC A N + K + PPS A Q + + LTCR +G P
Sbjct: 6146 SGEYTCKAENSIGTASSKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPI- 6204
Query: 255 DFLWIEEPGGVIVGKSK---------LGVEMLSESQLSDGKKFKCVTSHIVGPESGASCM 305
W + GV++ + + + ++ LS ++ C S+ +G S ++ +
Sbjct: 6205 QVCWYRD--GVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARL 6262
Query: 306 VQI---RGPSLLSEPMKT-CFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRH 361
+ P +P+ G + C V+GA P +I W ++ + I+P +
Sbjct: 6263 TAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQP-MRITWSKDNKE----IRPGGNY 6317
Query: 362 LITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEP 408
IT G L I + D G Y C+A + VG LSVKEP
Sbjct: 6318 TITCVGNTPHLRILKVGKG-DSGQYTCQATNDVGKDMCSAQLSVKEP 6363
Score = 57.0 bits (136), Expect = 4e-08
Identities = 92/404 (22%), Positives = 151/404 (37%), Gaps = 69/404 (17%)
Query: 36 VHENVTLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSLV---DATSLHIES 92
+ E TL C +++WY+ +++ LR A P + + + SL I
Sbjct: 7033 IGEPATLQCKVDGTPEIRISWYKEHTK----------LRSA-PAYKMQFKNNVASLVINK 7081
Query: 93 LSLGDEGIYTCQEILNVTQWFQVWLQVASGPYQIEVHIVATGTLPN------GTLYAARG 146
+ D G Y+C+ +V VAS V ++ LP ++ G
Sbjct: 7082 VDHSDVGEYSCKADNSVGA-------VASSA----VLVIKARKLPPFFARKLKDVHETLG 7130
Query: 147 SQVDFSCNSSSRPPPVVEWWFQALNSSSE-----SFGHNLTVNFFSLLLISPNLQGNYTC 201
V F C + P V W+ + + SF HN+ +L + G Y C
Sbjct: 7131 FPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNVAT--LQILQTDQSHIGQYNC 7188
Query: 202 LALNQLSKRHRKVTTELLVYYPPP-----SAPQCWAQMASGSFMLQLTCRWDGGYPDPDF 256
A N L L + PP A SG+F +T G
Sbjct: 7189 SASNPLGTASSSAKLILSEHEVPPFFDLKPVSVDLALGESGTFKCHVT-----GTAPIKI 7243
Query: 257 LWIEE-----PGG-----VIVGKSKLGVEMLSESQLSDGKKFKCVTSHIVGPESGASCMV 306
W ++ PGG ++ + L V + + D ++ C S+I G +S ++ +
Sbjct: 7244 TWAKDNREIRPGGNYKMTLVENTATLTVLKVGKG---DAGQYTCYASNIAGKDSCSAQLG 7300
Query: 307 QIRGPSLLS--EPMKTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLIT 364
P + EP + C++ G+ P K+LW ++ T+ IQ SS+ ++
Sbjct: 7301 VQEPPRFIKKLEPSRIVKQDEFTRYECKIGGS-PEIKVLWYKDETE----IQESSKFRMS 7355
Query: 365 QDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEP 408
+ L +HN S + D G Y C A + G L VKEP
Sbjct: 7356 FVDSVAVLEMHNLSVE-DSGDYTCEAHNAAGSASSSTSLKVKEP 7398
Score = 56.2 bits (134), Expect = 7e-08
Identities = 74/349 (21%), Positives = 138/349 (39%), Gaps = 39/349 (11%)
Query: 79 RFSLVDATS-LHIESLSLGDEGIYTCQEILNVTQWFQVWLQVASGPYQIEVHIVATGTLP 137
+ S+ D S L I S D G YT F+V V + ++++ P
Sbjct: 4626 KISVTDTVSILKIISTEKKDSGEYT----------FEVQNDVGRSSCKARINVLDLIIPP 4675
Query: 138 NGT-----LYAARGSQVDFSCNSSSRPPPVVEWWF--QALNSSSE-SFGHNLTVNFFSLL 189
+ T + + +GS +D C + P ++W+ Q +++S + F + F +
Sbjct: 4676 SFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEIS 4735
Query: 190 LISPNLQGNYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRWDG 249
+ G YTC A N+ H + + L V PP + +Q + + +QL G
Sbjct: 4736 QLEGTDSGTYTCSATNKAG--HNQCSGHLTVKEPPYFVEKPQSQDVNPNTRVQLKALVGG 4793
Query: 250 GYPDPDFLWIEEPGGVIVGKSK--------LGVEMLSESQLSDGKKFKCVTSHIVGPESG 301
P W ++ + G ++ +E+ + ++ +D + C S+ VG +
Sbjct: 4794 TAP-MTIKWFKDNKELHSGAARSVWKDDTSTSLELFA-AKATDSGTYICQLSNDVGTATS 4851
Query: 302 ASCMVQIRGPSLLSEPMKTCF--TGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSS 359
+ + P + +P G + T CQ++G P ++ W + + I
Sbjct: 4852 KATLFVKEPPQFIKKPSPVLVLRNGQSTTFECQITGT-PKIRVSWYLDGNEITAI----Q 4906
Query: 360 RHLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEP 408
+H I+ +T I + + G Y+C A + G I L VKEP
Sbjct: 4907 KHGISFIDGLATFQISGARVE-NSGTYVCEARNDAGTASCSIELKVKEP 4954
Score = 55.5 bits (132), Expect = 1e-07
Identities = 87/397 (21%), Positives = 146/397 (36%), Gaps = 47/397 (11%)
Query: 28 LEAVVIGEVHENVTLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSLVDATS 87
LEA + + E++ L C +V+W+RN+SE N S +
Sbjct: 6370 LEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSF--------INSVAL 6421
Query: 88 LHIESLSLGDEGIYTCQEILNVTQWFQVWLQVASGPYQIEVHIVATGTLPNGTLYAARGS 147
L I S D G Y C+ V AS + V T + A +GS
Sbjct: 6422 LTINEASAEDSGDYICEAHNGVGD--------ASCSTALTVKAPPVFTQKPSPVGALKGS 6473
Query: 148 QVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISPNLQ----GNYTCLA 203
V C S PP V W + S +T F L NL+ G Y C A
Sbjct: 6474 DVILQCEISGTPPFEVV-WVKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKA 6532
Query: 204 LNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSFML----QLTCRWDGGYPDPDFLWI 259
N++ T V + P P+ +++ S ++ +L +G P +W+
Sbjct: 6533 TNEVGSD----TCSCSVKFKEP--PRFVKKLSDTSTLIGDAVELRAIVEGFQP-ISVVWL 6585
Query: 260 EEPGGVIVGKSKLGVE--------MLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGP 311
++ G VI + L + S+ K+ C + G ++ + +
Sbjct: 6586 KDRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPA 6645
Query: 312 SLLSEPMKTCFTGGN-VTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNS 370
++ +P T GN L C V+G P W ++ + + S+H IT + +
Sbjct: 6646 RIIEKPEPMTVTTGNPFALECVVTGT-PELSAKWFKDGRE----LSADSKHHITFINKVA 6700
Query: 371 TLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKE 407
+L I C++ D+G Y + VG + + V +
Sbjct: 6701 SLKI-PCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSD 6736
Score = 53.9 bits (128), Expect = 4e-07
Identities = 77/343 (22%), Positives = 132/343 (38%), Gaps = 38/343 (11%)
Query: 84 DATSLHIESLSLGDEGIYTCQEILNVTQWFQVWLQVASGPYQIEVHIVATGTLPNGTLYA 143
+ S I+S+ D G YT F+V S + ++ P+ T
Sbjct: 5194 NVASFRIQSVMKQDSGQYT----------FKVENDFGSSSCDAYLRVLDQNIPPSFTKKL 5243
Query: 144 AR-----GSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISPNLQ-- 196
+ GS + C S P + WF+ S S + L + S+ L NL+
Sbjct: 5244 TKMDKVLGSSIHMECKVSGSLP-ISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELE 5302
Query: 197 --GNYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPDP 254
NYTC N + L V PP + Q A ++ G P
Sbjct: 5303 DTANYTCKVSNVAGDD--ACSGILTVKEPPSFLVKPGRQQAIPDSTVEFKAILKGT-PPF 5359
Query: 255 DFLWIEEPGGVIVG-KSKLGVE------MLSESQLSDGKKFKCVTSHIVGPESGASCMVQ 307
W ++ ++ G K +G+E L S ++ C ++ VG +S + ++
Sbjct: 5360 KIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLV 5419
Query: 308 IRGPSLLS--EPMKTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQ 365
P + E K G + L C+++G+ P +++W RN E + S ++ +T
Sbjct: 5420 TEPPKFVKKLEASKIVKAGDSSRLECKIAGS-PEIRVVWFRN----EHELPASDKYRMTF 5474
Query: 366 DGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEP 408
+ + ++N S + D G +IC A +P G + VKEP
Sbjct: 5475 IDSVAVIQMNNLSTE-DSGDFICEAQNPAGSTSCSTKVIVKEP 5516
Score = 50.8 bits (120), Expect = 3e-06
Identities = 84/372 (22%), Positives = 135/372 (36%), Gaps = 41/372 (11%)
Query: 54 VTWYRNNSEPVFLLSSNSSLRPAEPRFSLVDATSLHIESLSLGDEGIYTCQEILNV-TQW 112
+ W+++N E L S + A + +TSL + + D G Y CQ +V T
Sbjct: 4799 IKWFKDNKE----LHSGA----ARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTAT 4850
Query: 113 FQVWLQVASGPYQIEVHIVATGTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWWFQ---- 168
+ L V P I+ P+ L G F C + P V W+
Sbjct: 4851 SKATLFVKEPPQFIKK--------PSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEI 4902
Query: 169 -ALNSSSESFGHNLTVNFFSLLLISPNLQGNYTCLALNQLSKRHRKVTTELLVYYPPPSA 227
A+ SF L F + G Y C A N + EL V PP
Sbjct: 4903 TAIQKHGISFIDGLAT--FQISGARVENSGTYVCEARNDAGTASCSI--ELKVKEPPTFI 4958
Query: 228 PQCWAQMASGSFMLQLTCRWDGGYPDPDFLWIEEPGGVIVGKSKLGVEMLSESQL----- 282
+ ++L C G P + W++ + K + +S L
Sbjct: 4959 RELKPVEVVKYSDVELECEVTGT-PPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKC 5017
Query: 283 --SDGKKFKCVTSHIVGPESGASCMVQIRGPSLLSE-PMKTCFTGGNVTLTCQVSGAYPP 339
SD +++C+ S+ G S ++ + PS + + T + T V+G+ PP
Sbjct: 5018 DPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKKIENTTTVLKSSATFQSTVAGS-PP 5076
Query: 340 AKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREM 399
I WL++ + I+ I+ +TL I + G Y C+A + GV
Sbjct: 5077 ISITWLKD----DQILDEDDNVYISFVDSVATLQIRSVDNG-HSGRYTCQAKNESGVERC 5131
Query: 400 EIWLSVKEPLNI 411
+L V+EP I
Sbjct: 5132 YAFLLVQEPAQI 5143
Score = 49.3 bits (116), Expect = 9e-06
Identities = 62/278 (22%), Positives = 110/278 (39%), Gaps = 30/278 (10%)
Query: 146 GSQVDFSCNSSSRPPPVVEWWFQALNSSSESF-GHNLTVNF------FSLLLISPNLQGN 198
G+ V F+ PP V W+ SSE G V+ L + + G
Sbjct: 7789 GTNVTFTSIVKGTPPFSVSWF----KGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGE 7844
Query: 199 YTCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLW 258
YTC+ N+ K TT L + P + L L + G P W
Sbjct: 7845 YTCIVSNEAGKA--SCTTHLYIKAPAKFVKRLNDYSIEKGKPLILEGTFTGT-PPISVTW 7901
Query: 259 IEEPGGV-------IVGKSKLGVEMLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGP 311
+ V I K + + S + D ++ C + G +S ++ ++ + P
Sbjct: 7902 KKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEPP 7961
Query: 312 SLLS--EPMKTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQN 369
+ EP+K G + +L CQ++G P + W + T+ ++P++ + +
Sbjct: 7962 YFVKQLEPVKVS-VGDSASLQCQLAGT-PEIGVSWYKGDTK----LRPTTTYKMHFRNNV 8015
Query: 370 STLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKE 407
+TL + + D G YIC+A++ VG +L+V+E
Sbjct: 8016 ATLVFNQVDIN-DSGEYICKAENSVGEVSASTFLTVQE 8052
Score = 48.1 bits (113), Expect = 2e-05
Identities = 64/283 (22%), Positives = 99/283 (34%), Gaps = 21/283 (7%)
Query: 139 GTLYAARGSQVDFSCNSSSRPPPVVEWWFQA-LNSSSESFGHNLTVNFFSLLLISPNLQ- 196
G + G C + P VEW+ L +SS+ + SL ++S Q
Sbjct: 5711 GPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQD 5770
Query: 197 -GNYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMAS--GSFMLQLTCRWDGGYPD 253
G YT N + K ++ PPS + G+ + L C+ G P
Sbjct: 5771 AGTYTFQVQNNVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGVLGASCI-LECKVAGSSPI 5829
Query: 254 PDFLWIEEPGGVIVG-------KSKLGVEMLSESQLSDGKKFKCVTSHIVGPESGASCMV 306
W E ++ G + L+ SD + CV +++ G + + +
Sbjct: 5830 -SVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLT 5888
Query: 307 QIRGPSLLSEPMKT-CFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQ 365
PS + EP G NVT T + G PP K+ W R + + R I
Sbjct: 5889 VQEPPSFVKEPEPLEVLPGKNVTFTSVIRGT-PPFKVNWFRGARE----LVKGDRCNIYF 5943
Query: 366 DGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEP 408
+ + L + N G Y C + G L VKEP
Sbjct: 5944 EDTVAELELFNIDIS-QSGEYTCVVSNNAGQASCTTRLFVKEP 5985
Score = 47.0 bits (110), Expect = 4e-05
Identities = 81/373 (21%), Positives = 131/373 (35%), Gaps = 46/373 (12%)
Query: 54 VTWYRNNSEPVFLLSSNSSLRPAEPRFSLVDATSLHIESLSLGDEGIYTCQEILNVTQWF 113
V+WY++ E L S + F TS+HI ++ D G Y C+ +V
Sbjct: 7430 VSWYKDKRE----LRSGKKYKIMSENF----LTSIHILNVDAADIGEYQCKATNDVGSDT 7481
Query: 114 QVWLQVASGPYQIEVHIVATGTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWWFQALNSS 173
V P + + T+ G +V P V W+
Sbjct: 7482 CVGSIALKAPPRFVKKLSDISTVV--------GKEVQLQTTIEGAEPISVVWFKDKGEIV 7533
Query: 174 SES------FGHNLTVNFFSLLLISPNLQGNYTCLALNQLSKRHRKVTTELLVYYPPPSA 227
ES + N+ FS + P G YTC N + T +L
Sbjct: 7534 RESDNIWISYSENIATLQFSR--VEPANAGKYTCQIKNDAGMQECFATLSVLEPATIVEK 7591
Query: 228 PQCWAQMASGSFMLQLTCRWDGGYPDPDFLWIEEPGGVIVGKSKLGVEMLSESQ------ 281
P+ + L+ T G P+ W ++ G + +K + ++
Sbjct: 7592 PESIKVTTGDTCTLECTV---AGTPELSTKWFKD-GKELTSDNKYKISFFNKVSGLKIIN 7647
Query: 282 --LSDGKKFKCVTSHIVGPES-GASCMVQIRG--PSLLSEPMKTC-FTGGNVTLTCQVSG 335
SD + + VG +S AS V R PS + +T +G +V + C+V G
Sbjct: 7648 VAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECKVYG 7707
Query: 336 AYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVG 395
+ PP + W + I ++ T LT+ N ++ D G Y C A + G
Sbjct: 7708 S-PPISVSWFHEGNE----ISSGRKYQTTLTDNTCALTV-NMLEESDSGDYTCIATNMAG 7761
Query: 396 VREMEIWLSVKEP 408
E L+V+EP
Sbjct: 7762 SDECSAPLTVREP 7774
Score = 46.2 bits (108), Expect = 8e-05
Identities = 57/282 (20%), Positives = 108/282 (38%), Gaps = 33/282 (11%)
Query: 146 GSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFS------LLLISPNLQGNY 199
G C + P +W+ +S++ ++FF+ ++ ++P+ G Y
Sbjct: 7600 GDTCTLECTVAGTPELSTKWFKDGKELTSDN---KYKISFFNKVSGLKIINVAPSDSGVY 7656
Query: 200 TCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQM--ASGSFMLQLTCRWDGGYPDPDFL 257
+ N + K + ++ PPS + + SGS ++ + C+ G P
Sbjct: 7657 SFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVV-MECKVYGS-PPISVS 7714
Query: 258 WIEEPGGVIVGKS----------KLGVEMLSESQLSDGKKFKCVTSHIVGPESGASCMVQ 307
W E + G+ L V ML ES D + C+ +++ G + ++ +
Sbjct: 7715 WFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGD---YTCIATNMAGSDECSAPLTV 7771
Query: 308 IRGPSLLSEP-MKTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQD 366
PS + +P TG NVT T V G PP + W + ++ + P R ++ +
Sbjct: 7772 REPPSFVQKPDPMDVLTGTNVTFTSIVKGT-PPFSVSWFKGSSE----LVPGDRCNVSLE 7826
Query: 367 GQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEP 408
+ L + + G Y C + G L +K P
Sbjct: 7827 DSVAELELFDVDTS-QSGEYTCIVSNEAGKASCTTHLYIKAP 7867
Score = 46.2 bits (108), Expect = 8e-05
Identities = 62/286 (21%), Positives = 115/286 (40%), Gaps = 33/286 (11%)
Query: 143 AARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFF------SLLLISPNLQ 196
A G DF C+ + P V W A +S G +++ ++L +
Sbjct: 8164 AVVGESADFECHVTGTQPIKVSW---AKDSREIRSGGKYQISYLENSAHLTVLKVDKGDS 8220
Query: 197 GNYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMAS----GSFMLQLTCRWDGGYP 252
G YTC A+N++ K + PPS + ++ SF L+ R G P
Sbjct: 8221 GQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKRLSETVEETEGNSFKLE--GRVAGSQP 8278
Query: 253 DPDFLWIEEPGGV-------IVGKSKLGVEMLSESQLSDGKKFKCVTSHIVGPESGASCM 305
W + + I K+ V + ++ ++D + C S+ G S +
Sbjct: 8279 IT-VAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSI 8337
Query: 306 V--QIRGPSLLSEPMK--TCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRH 361
V + + P + + + T G V L+C V G+ P +I WL+ + I+PS R
Sbjct: 8338 VIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGS-EPIRIQWLKAGRE----IKPSDRC 8392
Query: 362 LITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKE 407
+ + L + + ++ D G Y+C+A + G + +++K+
Sbjct: 8393 SFSFASGTAVLELRDVAK-ADSGDYVCKASNVAGSDTTKSKVTIKD 8437
Score = 44.7 bits (104), Expect = 2e-04
Identities = 73/359 (20%), Positives = 136/359 (37%), Gaps = 45/359 (12%)
Query: 53 QVTWYRNNSEPVFLLSSNSSLRPAEPRFSLVDATS-LHIESLSLGDEGIYTCQEILNV-- 109
+V WY++ +E + +S R S VD+ + L + +LS+ D G YTC E N
Sbjct: 7336 KVLWYKDETE----IQESSKFR-----MSFVDSVAVLEMHNLSVEDSGDYTC-EAHNAAG 7385
Query: 110 TQWFQVWLQVASGP-YQIEVHIVATGTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWWFQ 168
+ L+V P ++ + H + T +G+ V C PP V W+
Sbjct: 7386 SASSSTSLKVKEPPIFRKKPHPIET----------LKGADVHLECELQGTPPFHVSWYKD 7435
Query: 169 ALNSSSESFGHNLTVNFFS---LLLISPNLQGNYTCLALNQLSKRHRKVTTELLVYYPPP 225
S ++ NF + +L + G Y C A N + + + PP
Sbjct: 7436 KRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGS--DTCVGSIALKAPPR 7493
Query: 226 SAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWIEEPGGVIVGKSKLGVE--------ML 277
+ +QL +G P +W ++ G ++ + +
Sbjct: 7494 FVKKLSDISTVVGKEVQLQTTIEGAEP-ISVVWFKDKGEIVRESDNIWISYSENIATLQF 7552
Query: 278 SESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSLLSEPMK-TCFTGGNVTLTCQVSGA 336
S + ++ K+ C + G + + + + +++ +P TG TL C V+G
Sbjct: 7553 SRVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIVEKPESIKVTTGDTCTLECTVAGT 7612
Query: 337 YPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVG 395
P W ++ + + +++ I+ + S L I N + D G Y +PVG
Sbjct: 7613 -PELSTKWFKDGKE----LTSDNKYKISFFNKVSGLKIINVAPS-DSGVYSFEVQNPVG 7665
Score = 43.9 bits (102), Expect = 4e-04
Identities = 80/379 (21%), Positives = 146/379 (38%), Gaps = 55/379 (14%)
Query: 54 VTWYRNNSEPVFLLSSNSSLRPAEPRFSLVDATSLHIESLSLGDEGIYTCQEILNVTQWF 113
+ W++ N E L+S S E S SL + + D G YTC+ + NV
Sbjct: 4237 IRWFKGNKE---LVSGGSCYITKEALES-----SLELYLVKTSDSGTYTCK-VSNVAGG- 4286
Query: 114 QVWLQVASGPYQIEVHIVATGTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWWFQALNSS 173
++ ++ + E P+ L +G +C + PP + W F
Sbjct: 4287 ---VECSANLFVKEPATFVEKLEPSQLL--KKGDATQLACKVTGTPPIKITW-FANDREI 4340
Query: 174 SESFGHNLTVNFFSLLLISPNL----QGNYTCLALNQLSKRHRKVTTELLVYYPPPSAPQ 229
ES H ++ + +L ++ G Y C A N+ H ++ ++V P +
Sbjct: 4341 KESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDH--CSSIVIVKESPYFTKE 4398
Query: 230 CWAQMASGSFMLQLTCRWDGGYPDPDFLWIEEPGGVIVG---KSKLGVEMLSESQL---- 282
+ + L G P + W ++ + G K+ + ++S L
Sbjct: 4399 FKPIEVLKEYDVMLLAEV-AGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVA 4457
Query: 283 SDGKKFKCVTSHIVGPESGASCMVQIRGPSLLSEPMKTCFT--GGNVTLTCQVSGAYPPA 340
+D +++C ++ VG S S V +R P + +++ + GG + G+ P
Sbjct: 4458 ADAGEYQCRVTNEVG-SSICSARVTLREPPSFIKKIESTSSLRGGTAAFQATLKGSLP-I 4515
Query: 341 KILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQDL--------DEGYYICRADS 392
+ WL++ + IT+D N +T N L +G Y+C+A +
Sbjct: 4516 TVTWLKDSDE------------ITED-DNIRMTFENNVASLYLSGIEVKHDGKYVCQAKN 4562
Query: 393 PVGVREMEIWLSVKEPLNI 411
G++ LSVKEP I
Sbjct: 4563 DAGIQRCSALLSVKEPATI 4581
Score = 41.2 bits (95), Expect = 0.002
Identities = 98/463 (21%), Positives = 169/463 (36%), Gaps = 58/463 (12%)
Query: 47 ISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRF----SLVDATSLHIESLSLGDEGIYT 102
+SG +V+WY S + ++P+ RF D L I DEG YT
Sbjct: 3368 VSGTDLKVSWY----------SKDKKIKPS--RFFRMTQFEDTYQLEIAEAYPEDEGTYT 3415
Query: 103 ---CQEILNVTQWFQVWLQVASG------PYQIEVHIVATGTLPNGT--LYAARGSQVDF 151
+ V+ + L+ +IE+ + A + L A G F
Sbjct: 3416 FVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKAAPVIKRKIEPLEVALGHLAKF 3475
Query: 152 SCNSSSRPPPVVEWWF---QALNSSSESFGHNLTVNFFSLLLISPNLQGNYTCLALNQLS 208
+C S P +W+ + S S + ++ +L G YTC A N+
Sbjct: 3476 TCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYG 3535
Query: 209 KRHRKVTTELLVYYPPP--SAPQCWAQMA--SGSFMLQLTCRWDGGYPDPDFLWIEE--- 261
T + YPP S P+ + F+ +T G P + +W ++
Sbjct: 3536 SVSCTATLTVTEAYPPTFLSRPKSLTTFVGKAAKFICTVT-----GTPVIETIWQKDGAA 3590
Query: 262 ----PGGVIVGKSKLGVEMLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSLLSE- 316
P I + LS + D + C S+ G + + ++ I P + E
Sbjct: 3591 LSPSPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDKPHFIKEL 3650
Query: 317 -PMKTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIH 375
P+++ V L CQV + W ++ + + P + I + + +TL I
Sbjct: 3651 EPVQSAINK-KVHLECQVDEDRK-VTVTWSKDGQK----LPPGKDYKICFEDKIATLEIP 3704
Query: 376 NCSQDLDEGYYICRADSPVGVREMEIWLSVKEPLNIGGIVGTIVSLLLLGLAIISGLLLH 435
++ D G Y+C A + G ++V+EP + V L+L G + L
Sbjct: 3705 -LAKLKDSGTYVCTASNEAGSSSCSATVTVREPPSFVKKVDPSY-LMLPGESARLHCKLK 3762
Query: 436 YSPVF--CWKVGNTSRGQNMDDVMVLVDSEEEEEEEEEEEEDA 476
SPV W N ++ M V+SE + + + ED+
Sbjct: 3763 GSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDS 3805
Score = 40.4 bits (93), Expect = 0.004
Identities = 58/275 (21%), Positives = 103/275 (37%), Gaps = 19/275 (6%)
Query: 146 GSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLI---SPNLQGNYTCL 202
G+ C + P +W+ S++S H +N + L I + +G Y+
Sbjct: 6659 GNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFE 6718
Query: 203 ALNQLSKRHRKVTTELLVYYPPPSAPQCWAQM-ASGSFMLQLTCRWDGGYPDPDFLWIEE 261
N + K + V+ + PPS + + A + L CR G P W ++
Sbjct: 6719 VKNSVGKSNCTVSVHVSDRIVPPSFIRKLKDVNAILGASVVLECRVSGSAPI-SVGWFQD 6777
Query: 262 PGGVIVG-------KSKLGVEMLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSLL 314
++ G + LS + SD + CV +++ G + ++ + PS
Sbjct: 6778 GNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSFE 6837
Query: 315 SEPMKT-CFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLT 373
P G ++T T + G PP K+ W + + + P I+ + + L
Sbjct: 6838 QTPDSVEVLPGMSLTFTSVIRGT-PPFKVKWFKGSRE----LVPGESCNISLEDFVTELE 6892
Query: 374 IHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEP 408
+ Q L+ G Y C + G L VKEP
Sbjct: 6893 LFEV-QPLESGDYSCLVTNDAGSASCTTHLFVKEP 6926
Score = 39.3 bits (90), Expect = 0.009
Identities = 88/436 (20%), Positives = 163/436 (37%), Gaps = 57/436 (13%)
Query: 28 LEAVVIGEVHENVTLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSLVDATS 87
LEA I + ++ L C +V W+RN E L +S+ R + +D+ +
Sbjct: 5429 LEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHE---LPASDKY------RMTFIDSVA 5479
Query: 88 -LHIESLSLGDEGIYTCQEILNVTQWFQVWLQVASGPYQIEVHIVATGTLPNGTLYAARG 146
+ + +LS D G + C+ + P TL N
Sbjct: 5480 VIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPIVETLKN-------- 5531
Query: 147 SQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFS---LLLISPNLQGNYTCLA 203
++V C S PP V W+ S + NF + +L + + G Y C A
Sbjct: 5532 AEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKA 5591
Query: 204 LNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFL-WIEEP 262
N++ T +L PP + + +L +G P F+ W++E
Sbjct: 5592 QNEVGSDTCVCTVKL--KEPPRFVSKLNSLTVVAGEPAELQASIEGA--QPIFVQWLKEK 5647
Query: 263 GGVIVGKSKLGVEML--------SESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSLL 314
VI + + + ++++ ++ K+ C + G + ++ + P+++
Sbjct: 5648 EEVIRESENIRITFVENVATLQFAKAEPANAGKYICQIKNDGGMRENMATLMVLE-PAVI 5706
Query: 315 SE---PMKTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNST 371
E PM T G TL C+V+G P + W ++ ++ S +H + + S+
Sbjct: 5707 VEKAGPM-TVTVGETCTLECKVAGT-PELSVEWYKD----GKLLTSSQKHKFSFYNKISS 5760
Query: 372 LTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEPL----------NIGGIVGT--IV 419
L I + + D G Y + + VG + V + N GG++G I+
Sbjct: 5761 LRILSVERQ-DAGTYTFQVQNNVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGVLGASCIL 5819
Query: 420 SLLLLGLAIISGLLLH 435
+ G + IS H
Sbjct: 5820 ECKVAGSSPISVAWFH 5835
Score = 38.9 bits (89), Expect = 0.012
Identities = 84/391 (21%), Positives = 150/391 (38%), Gaps = 53/391 (13%)
Query: 39 NVTLHCGNISGLRG-QVTWYRNNSEPVFLLSSNSSLRPAEPRFSLVDATSLHIESLSLGD 97
N L C +SG +++W+++ + + S+ R FS L I S + D
Sbjct: 3847 NALLQC-EVSGTGPFEISWFKDKKQ----IRSSKKYR----LFSQKSLVCLEIFSFNSAD 3897
Query: 98 EGIYTCQEILNVTQWFQVWLQVASGPYQIEVHI---VATGTLPNGTLYAARGSQVDFSCN 154
G Y C V + + + P + +A G A RGS+
Sbjct: 3898 VGEYECVVANEVGKCGCMATHLLKEPPTFVKKVDDLIALGGQTVTLQAAVRGSE------ 3951
Query: 155 SSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISPNLQ----GNYTCLALNQLSKR 210
P+ W + E ++ + +LI P++Q G YTCLA N+ +
Sbjct: 3952 ------PISVTWMKGQEVIREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQ 4005
Query: 211 HRKVTTELLVYYPPPSAPQC-WAQMASGS-FMLQLTCRWDGGYPDPDFLWIEEPGGVIVG 268
EL+V P + Q+ +G L+ T G P+ W ++ ++
Sbjct: 4006 TS--VGELIVKEPAKIIERAELIQVTAGDPATLEYTV---AGTPELKPKWYKDGRPLVAS 4060
Query: 269 KS-----KLGVEMLS--ESQLSDGKKFKCVTSHIVGPESGASCMVQIRGP--SLLSEPMK 319
K K V L ++L D ++ S+ VG S + + ++P++
Sbjct: 4061 KKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIAPFFTKPLR 4120
Query: 320 TC--FTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNC 377
G L C+++G+ P ++ W ++ + I S R+ I ++L I
Sbjct: 4121 NVDSVVNGTCRLDCKIAGSLP-MRVSWFKDGKE----IAASDRYRIAFVEGTASLEIIRV 4175
Query: 378 SQDLDEGYYICRADSPVGVREMEIWLSVKEP 408
+ D G + CRA + VG ++ L V+EP
Sbjct: 4176 DMN-DAGNFTCRATNSVGSKDSSGALIVQEP 4205
Score = 38.9 bits (89), Expect = 0.012
Identities = 33/128 (25%), Positives = 56/128 (43%), Gaps = 7/128 (5%)
Query: 282 LSDGKKFKCVTSHIVGPESGASCMVQIRGPSLLSEP-MKTCFTGGNVTLTCQVSGAYPPA 340
++D F C ++ VG + + ++ PS +++P K G V L G+ P
Sbjct: 4177 MNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPGSKDVLPGSAVCLKSTFQGS-TPL 4235
Query: 341 KILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREME 400
I W + E++ S IT++ S+L ++ + D G Y C+ + G E
Sbjct: 4236 TIRWFKG--NKELVSGGSC--YITKEALESSLELY-LVKTSDSGTYTCKVSNVAGGVECS 4290
Query: 401 IWLSVKEP 408
L VKEP
Sbjct: 4291 ANLFVKEP 4298
Score = 37.7 bits (86), Expect = 0.027
Identities = 78/386 (20%), Positives = 131/386 (33%), Gaps = 44/386 (11%)
Query: 40 VTLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSLVDATSLHIESLSLGDEG 99
V+L C +V WY++ + L S+ + A F TS+HI ++ D G
Sbjct: 5534 VSLECELSGTPPFEVVWYKDKRQ----LRSSKKYKIASKNFH----TSIHILNVDTSDIG 5585
Query: 100 IYTCQEILNVTQWFQVWLQVASGPYQIEVHIVATGTLPNGTLYAARGSQVDFSCNSSSRP 159
Y C+ V V P + + +L G + +
Sbjct: 5586 EYHCKAQNEVGSDTCVCTVKLKEPPRFVSKL--------NSLTVVAGEPAELQASIEGAQ 5637
Query: 160 PPVVEWWFQALNSSSESFGHNLT----VNFFSLLLISPNLQGNYTCLALNQLSKRHRKVT 215
P V+W + ES +T V P G Y C N R T
Sbjct: 5638 PIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYICQIKNDGGMRENMAT 5697
Query: 216 TELLVYYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWIEEPGGVIVGK------ 269
L+V P + + L C+ G P+ W ++ G ++
Sbjct: 5698 --LMVLEPAVIVEKAGPMTVTVGETCTLECK-VAGTPELSVEWYKD-GKLLTSSQKHKFS 5753
Query: 270 --SKLGVEMLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRG---PSLLSEPMKTC--F 322
+K+ + + D + + VG +S + +V + P + +K
Sbjct: 5754 FYNKISSLRILSVERQDAGTYTFQVQNNVG-KSSCTAVVDVSDRAVPPSFTRRLKNTGGV 5812
Query: 323 TGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQDLD 382
G + L C+V+G+ P + W T+ I +++ T TL + N D
Sbjct: 5813 LGASCILECKVAGS-SPISVAWFHEKTK----IVSGAKYQTTFSDNVCTLQL-NSLDSSD 5866
Query: 383 EGYYICRADSPVGVREMEIWLSVKEP 408
G Y C A + G E L+V+EP
Sbjct: 5867 MGNYTCVAANVAGSDECRAVLTVQEP 5892
Score = 37.4 bits (85), Expect = 0.035
Identities = 34/126 (26%), Positives = 54/126 (42%), Gaps = 15/126 (11%)
Query: 140 TLYAARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISPNLQ--- 196
T+ G+ + + S RPPPV+ W Q ++ +S + T +SLL++ +
Sbjct: 29455 TVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIID--TTESYSLLIVDKVNRYDA 29512
Query: 197 GNYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRW-----DGGY 251
G YT A NQ K + T + VY P P + S +T W DGG
Sbjct: 29513 GKYTIEAENQSGK--KSATVLVKVYDTPGPCPSVKVKEVSRD---SVTITWEIPTIDGGA 29567
Query: 252 PDPDFL 257
P +++
Sbjct: 29568 PVNNYI 29573
Score = 36.6 bits (83), Expect = 0.060
Identities = 35/140 (25%), Positives = 50/140 (35%), Gaps = 23/140 (16%)
Query: 277 LSESQLSD--------GKKFKCVTSHIVGPESGASCMVQIRGPSLLSEPMKTCFTGGNVT 328
+SE++ SD G+ VT ++ PE P +L E G
Sbjct: 3207 ISETRQSDAGEYTFVAGRNRSSVTLYVNAPEP----------PQVLQELQPVTVQSGKPA 3256
Query: 329 LTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQDLDEGYYIC 388
C V P KI W + E ++ + DGQ TL + + D Y C
Sbjct: 3257 RFCAVISGRPQPKISWYKE----EQLLSTGFKCKFLHDGQEYTLLLIEAFPE-DAAVYTC 3311
Query: 389 RADSPVGVREMEIWLSVKEP 408
A + GV LSV+ P
Sbjct: 3312 EAKNDYGVATTSASLSVEVP 3331
Score = 36.6 bits (83), Expect = 0.060
Identities = 73/342 (21%), Positives = 118/342 (34%), Gaps = 40/342 (11%)
Query: 86 TSLHIESLSLGDEGIYTCQEILNVTQWFQVWLQVASGPYQIEVHIVATGTLPNGTLYAAR 145
TSLHI +L D G Y C+ V P + + T TL
Sbjct: 6513 TSLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPPRFVKKLSDTSTLI-------- 6564
Query: 146 GSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTV--NFFSLLLISPNLQ--GNYTC 201
G V+ P V W ES ++ N +L L SP G Y C
Sbjct: 6565 GDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYIC 6624
Query: 202 LALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWIEE 261
N R +L P+ F L+ G P+ W ++
Sbjct: 6625 QIKNDAGMRECSAVLTVLEPARIIEKPEPMTVTTGNPFALECVVT---GTPELSAKWFKD 6681
Query: 262 PGGVIVGKSKLGVEMLSE--------SQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSL 313
G + SK + +++ +++SD + + VG ++C V +
Sbjct: 6682 -GRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGK---SNCTVSVHVSDR 6737
Query: 314 LSEPM-------KTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQD 366
+ P G +V L C+VSG+ P + W ++ E++ P + +++
Sbjct: 6738 IVPPSFIRKLKDVNAILGASVVLECRVSGS-APISVGWFQDGN--EIVSGPKCQSSFSEN 6794
Query: 367 GQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEP 408
L++ S D G Y C A + G E L+V+EP
Sbjct: 6795 VCTLNLSLLEPS---DTGIYTCVAANVAGSDECSAVLTVQEP 6833
Score = 34.7 bits (78), Expect = 0.23
Identities = 30/142 (21%), Positives = 59/142 (41%), Gaps = 8/142 (5%)
Query: 269 KSKLGVEMLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSLLS--EPMKTCFTGGN 326
+ K+ + ++L D + C S+ G S ++ + PS + +P G +
Sbjct: 3695 EDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPPSFVKKVDPSYLMLPGES 3754
Query: 327 VTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQDLDEGYY 386
L C++ G+ P ++ W +N + + S+ + + L I + + D G Y
Sbjct: 3755 ARLHCKLKGS-PVIQVTWFKNNKE----LSESNTVRMYFVNSEAILDITDVKVE-DSGSY 3808
Query: 387 ICRADSPVGVREMEIWLSVKEP 408
C A + VG + +KEP
Sbjct: 3809 SCEAVNDVGSDSCSTEIVIKEP 3830
Score = 34.7 bits (78), Expect = 0.23
Identities = 86/399 (21%), Positives = 149/399 (37%), Gaps = 62/399 (15%)
Query: 38 ENVTLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPA-EPRFSLVDATS-LHIESLSL 95
E+ T C ++TW ++N E +RP + +LV+ T+ L + +
Sbjct: 7227 ESGTFKCHVTGTAPIKITWAKDNRE----------IRPGGNYKMTLVENTATLTVLKVGK 7276
Query: 96 GDEGIYTCQEILNVT--QWFQVWLQVASGPYQIEVHIVATGTLPNGTLYAARGSQVD--- 150
GD G YTC N+ L V P I+ L +R + D
Sbjct: 7277 GDAGQYTCYAS-NIAGKDSCSAQLGVQEPPRFIK------------KLEPSRIVKQDEFT 7323
Query: 151 -FSCNSSSRPPPVVEWW-----FQALNSSSESFGHNLTVNFFSLLLISPNLQGNYTCLAL 204
+ C P V W+ Q + SF ++ V + +S G+YTC A
Sbjct: 7324 RYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAV--LEMHNLSVEDSGDYTCEAH 7381
Query: 205 NQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWIEEPGG 264
N +T L V PP + + L C G P W ++
Sbjct: 7382 NAAGSASS--STSLKVKEPPIFRKKPHPIETLKGADVHLECELQGT-PPFHVSWYKDKRE 7438
Query: 265 VIVGKSKLGVEMLSESQLS----------DGKKFKCVTSHIVGPESGASCMVQIRGPSLL 314
+ GK +++SE+ L+ D +++C ++ VG ++ + ++ P
Sbjct: 7439 LRSGKK---YKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGS-IALKAPPRF 7494
Query: 315 SEPMKTCFT--GGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTL 372
+ + T G V L + GA P ++W ++ + I++ S I+ +TL
Sbjct: 7495 VKKLSDISTVVGKEVQLQTTIEGA-EPISVVWFKDKGE---IVRESDNIWISYSENIATL 7550
Query: 373 TIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEPLNI 411
+ + G Y C+ + G++E LSV EP I
Sbjct: 7551 QFSRV-EPANAGKYTCQIKNDAGMQECFATLSVLEPATI 7588
Score = 34.7 bits (78), Expect = 0.23
Identities = 26/72 (36%), Positives = 38/72 (52%), Gaps = 6/72 (8%)
Query: 324 GGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQDLDE 383
G L+CQ+ G P I W R + +IQ S ++ ++ DG+ TLT+ Q+ DE
Sbjct: 30547 GEAAQLSCQIVGR-PLPDIKWYRFGKE---LIQ-SRKYKMSSDGRTHTLTVMTEEQE-DE 30600
Query: 384 GYYICRADSPVG 395
G Y C A + VG
Sbjct: 30601 GVYTCIATNEVG 30612
Score = 34.3 bits (77), Expect = 0.30
Identities = 24/72 (33%), Positives = 35/72 (48%), Gaps = 7/72 (9%)
Query: 319 KTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCS 378
+T G L C+VS AK+ W +N T+ I S ++ I DG+ L IH+C+
Sbjct: 12294 QTVEEGATAVLECEVSREN--AKVKWFKNGTE----ILKSKKYEIVADGRVRKLVIHDCT 12347
Query: 379 QDLDEGYYICRA 390
+ D Y C A
Sbjct: 12348 PE-DIKTYTCDA 12358
Score = 33.9 bits (76), Expect = 0.39
Identities = 60/279 (21%), Positives = 108/279 (38%), Gaps = 24/279 (8%)
Query: 146 GSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISP---NLQGNYTCL 202
G C P V W+ S + VN ++L I+ G+Y+C
Sbjct: 3752 GESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCE 3811
Query: 203 ALNQLSKRHRKVTTELLVYYPPPSAPQCW-AQMASGSFMLQLTCRWDGGYPDPDFLWIEE 261
A+N + +TE+++ PP A + G+ L L C G P + W ++
Sbjct: 3812 AVNDVGSD--SCSTEIVIKEPPSFIKTLEPADIVRGTNAL-LQCEVSGTGPF-EISWFKD 3867
Query: 262 PGGV--------IVGKSKLGVEMLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSL 313
+ KS + +E+ S + G+ ++CV ++ VG + + P+
Sbjct: 3868 KKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGE-YECVVANEVGKCGCMATHLLKEPPTF 3926
Query: 314 LSEPMKTCFTGGN-VTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTL 372
+ + GG VTL V G+ P + W++ + +I+ + ++ + L
Sbjct: 3927 VKKVDDLIALGGQTVTLQAAVRGS-EPISVTWMKG----QEVIREDGKIKMSFSNGVAVL 3981
Query: 373 TIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEPLNI 411
I + G Y C A++ G + L VKEP I
Sbjct: 3982 IIPDVQISFG-GKYTCLAENEAGSQTSVGELIVKEPAKI 4019
Score = 33.5 bits (75), Expect = 0.51
Identities = 44/171 (25%), Positives = 68/171 (39%), Gaps = 30/171 (17%)
Query: 252 PDPDFLWIEEPGGVIVGKSKLGVEMLSESQLS--------------DGKKFKCV-TSHIV 296
P P F + + P KS+ GVE+ E +S G++ K T+ +
Sbjct: 877 PLPQFPFADTPDTY---KSEAGVEVKKEVGVSITGTTVREERFEVLHGREAKVTETARVP 933
Query: 297 GPESGASCMVQIRGPSLLSEPMK-TCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVII 355
P + + P+L+S T G +VTL C +SG YP + W R Q I
Sbjct: 934 APVE-----IPVTPPTLVSGLKNVTVIEGESVTLECHISG-YPSPTVTWYREDYQ----I 983
Query: 356 QPSSRHLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVK 406
+ S IT + L I + D G + C A + G +L+V+
Sbjct: 984 ESSIDFQITFQSGIARLMIREAFAE-DSGRFTCSAVNEAGTVSTSCYLAVQ 1033
Score = 32.7 bits (73), Expect = 0.86
Identities = 26/85 (30%), Positives = 42/85 (49%), Gaps = 10/85 (11%)
Query: 326 NVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQDLDEGY 385
+ T C+VS + A + W + T+ + S ++ DG+ +TIHN + D DEG
Sbjct: 8850 SATFECEVS--FDDAIVTWYKGPTE----LTESQKYNFRNDGRCHYMTIHNVTPD-DEGV 8902
Query: 386 Y--ICRADSPVGVRE-MEIWLSVKE 407
Y I R + R E++L+ KE
Sbjct: 8903 YSVIARLEPRGEARSTAELYLTTKE 8927
Score = 32.7 bits (73), Expect = 0.86
Identities = 48/196 (24%), Positives = 75/196 (38%), Gaps = 23/196 (11%)
Query: 39 NVTLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSLVDATSLHIESLSLGDE 98
N TL C + V WYR E +++ R E + L I S++ D
Sbjct: 30944 NATLVCKVTGHPKPIVKWYRQGKE---IIADGLKYRIQEFKGGY---HQLIIASVTDDDA 30997
Query: 99 GIYTCQEILNVTQWFQVWLQVASGPYQIEVHIVATGTLPN-----GTLYAARGSQVDFSC 153
+Y ++ Q V SG +EV + A LP G ++A RG V
Sbjct: 30998 TVY---QVRATNQGGSV-----SGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKI 31049
Query: 154 NSSSRPPPVVEWW-FQALNSSSESFGHNLTVNFFSLLL---ISPNLQGNYTCLALNQLSK 209
S +P PV+ W Q L ++ + +T +F SL+ + G Y A N+
Sbjct: 31050 PFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGI 31109
Query: 210 RHRKVTTELLVYYPPP 225
+ V ++ PP
Sbjct: 31110 DQKTVELDVADVPDPP 31125
Score = 32.3 bits (72), Expect = 1.1
Identities = 26/81 (32%), Positives = 38/81 (46%), Gaps = 7/81 (8%)
Query: 311 PSLLSEPMKTCFTGG-NVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQN 369
P+ +S+P G NV TC++SG P +I W +N + I SS I++
Sbjct: 33134 PAFISQPRSQNINEGQNVLFTCEISGE-PSPEIEWFKN----NLPISISSNVSISRSRNV 33188
Query: 370 STLTIHNCSQDLDEGYYICRA 390
+L I N S D G Y +A
Sbjct: 33189 YSLEIRNASVS-DSGKYTIKA 33208
Score = 31.6 bits (70), Expect = 1.9
Identities = 27/128 (21%), Positives = 56/128 (43%), Gaps = 12/128 (9%)
Query: 287 KFKCVTSHIVGPESGASCMVQIRGPS-----LLSEPMKTCFTGGNVTLTCQVSGAYPPAK 341
++ C ++ +G S ++ ++ G + + P+ G + C V+G P K
Sbjct: 8126 QYSCTATNPIGSASSSARLILTEGKNPPFFDIRLAPVDAV-VGESADFECHVTGTQP-IK 8183
Query: 342 ILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEI 401
+ W ++ + I+ ++ I+ ++ LT+ + D G Y C A + VG
Sbjct: 8184 VSWAKDSRE----IRSGGKYQISYLENSAHLTVLKVDKG-DSGQYTCYAVNEVGKDSCTA 8238
Query: 402 WLSVKEPL 409
L++KE L
Sbjct: 8239 QLNIKERL 8246
Score = 31.6 bits (70), Expect = 1.9
Identities = 17/50 (34%), Positives = 26/50 (52%), Gaps = 5/50 (10%)
Query: 337 YPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQDLDEGYY 386
YP K+ W + + ++PS + I+ DG TL + NC Q D+G Y
Sbjct: 8683 YPEIKLSWYKGTEK----LEPSDKFEISIDGDRHTLRVKNC-QLKDQGNY 8727
Score = 31.6 bits (70), Expect = 1.9
Identities = 25/93 (26%), Positives = 40/93 (43%), Gaps = 17/93 (18%)
Query: 146 GSQVDFSCNSSSRPPPVVEWW--FQALNSSSESFGHNLTV----NFFSLLLISPNLQGNY 199
G FSC++ P P V W Q L++S+ H +T + F + + + +GNY
Sbjct: 32575 GESARFSCDTDGEPVPTVTWLRKGQVLSTSAR---HQVTTTKYKSTFEISSVQASDEGNY 32631
Query: 200 TCLALNQLSKRHRKVT--------TELLVYYPP 224
+ + N K+ + T TE V PP
Sbjct: 32632 SVVVENSEGKQEAEFTLTIQKARVTEKAVTSPP 32664
Score = 30.8 bits (68), Expect = 3.3
Identities = 31/130 (23%), Positives = 49/130 (37%), Gaps = 23/130 (17%)
Query: 87 SLHIESLSLGDEGIYTCQEILNVTQWFQVWLQVASGPYQIEVHIVATGTLPNGTLYAAR- 145
+L I+ S DEGI TC + G + + + + L + + ++
Sbjct: 33093 TLTIKQASHRDEGILTCIS------------KTKEGIVKCQYDLTLSKELSDAPAFISQP 33140
Query: 146 -------GSQVDFSCNSSSRPPPVVEWWFQALN---SSSESFGHNLTVNFFSLLLISPNL 195
G V F+C S P P +EW+ L SS+ S + V + S +
Sbjct: 33141 RSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSD 33200
Query: 196 QGNYTCLALN 205
G YT A N
Sbjct: 33201 SGKYTIKAKN 33210
Score = 30.4 bits (67), Expect = 4.3
Identities = 11/33 (33%), Positives = 17/33 (51%)
Query: 135 TLPNGTLYAARGSQVDFSCNSSSRPPPVVEWWF 167
T+P T++ G V+ + RPPP W+F
Sbjct: 29742 TMPQKTIHVPAGRPVELVIPIAGRPPPAASWFF 29774
Score = 30.4 bits (67), Expect = 4.3
Identities = 23/91 (25%), Positives = 39/91 (42%), Gaps = 15/91 (16%)
Query: 146 GSQVDFSCNSSSRPPPVVEWW--------FQALNSSSESFGHNLTVNFFSLLLISPNLQG 197
G SC RP P ++W+ + SS+ H LTV + +G
Sbjct: 30547 GEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV-----MTEEQEDEG 30601
Query: 198 NYTCLALNQLSKRHRKVTTELLVYYPPPSAP 228
YTC+A N++ + + +++LL+ P P
Sbjct: 30602 VYTCIATNEVGE--VETSSKLLLQATPQFHP 30630
Score = 29.6 bits (65), Expect = 7.3
Identities = 19/36 (52%), Positives = 20/36 (55%), Gaps = 8/36 (22%)
Query: 462 SEEEE--------EEEEEEEEDAAVGEQEGAREREE 489
SEEEE EEE EEEE+A V E E E EE
Sbjct: 9498 SEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEE 9533
>gi|193083163 roundabout, axon guidance receptor, homolog 2 isoform
ROBO2a [Homo sapiens]
Length = 1394
Score = 65.1 bits (157), Expect = 2e-10
Identities = 65/282 (23%), Positives = 119/282 (42%), Gaps = 28/282 (9%)
Query: 144 ARGSQVDFSCNSSSRPPPVVEWWF---QALNSSSESFGHNLTVNFFSLLLI-------SP 193
++G +C + RP P +EW+ + + H + + SL + S
Sbjct: 59 SKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSK 118
Query: 194 NLQGNYTCLALNQLSKR-HRKVTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRWDGGYP 252
+G+Y C+A N L + R + E+ + +A+G + L C+ G+P
Sbjct: 119 PDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAI-LECQPPRGHP 177
Query: 253 DPDFLWIEEPGGVIVGKSKLGVE----MLSESQLSDGKKFKCVTSHIVGP-ESGASCMVQ 307
+P W ++ + + ++ + M+S ++ SD + CV +++VG +S + +
Sbjct: 178 EPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTV 237
Query: 308 IRGPSLLSEPM-KTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQD 366
P+ L P+ + V CQV G P + W ++ P R+ I D
Sbjct: 238 FERPTFLRRPINQVVLEEEAVEFRCQVQGD-PQPTVRWKKDDAD-----LPRGRYDIKDD 291
Query: 367 GQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEP 408
TL I + DEG Y+C A++ VG E L+V+ P
Sbjct: 292 ---YTLRIKK-TMSTDEGTYMCIAENRVGKMEASATLTVRAP 329
Score = 58.2 bits (139), Expect = 2e-08
Identities = 84/378 (22%), Positives = 139/378 (36%), Gaps = 33/378 (8%)
Query: 32 VIGEVHENVTLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSLVDATSLHIE 91
VI E TL+C + WY++ S R P SL +H
Sbjct: 56 VIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGR 115
Query: 92 SLSLGDEGIYTC--QEILNVTQWFQVWLQVASGPYQIEVHIVATGTLPNGT-LYAARGSQ 148
S DEG Y C + L + S +EV ++ N T + A G
Sbjct: 116 R-SKPDEGSYVCVARNYLG---------EAVSRNASLEVALLRDDFRQNPTDVVVAAGEP 165
Query: 149 VDFSCNSS-SRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISPNLQ--GNYTCLALN 205
C P P + W + + +++ L++ + G YTC+ N
Sbjct: 166 AILECQPPRGHPEPTIYWKKDKVRIDDKE--ERISIRGGKLMISNTRKSDAGMYTCVGTN 223
Query: 206 QLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWIEEPGGV 265
+ +R EL V+ P + Q+ ++ C+ G P P W ++ +
Sbjct: 224 MVGERDSD-PAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGD-PQPTVRWKKDDADL 281
Query: 266 IVGKSKLGVEM---LSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSLLSEPMKTCF 322
G+ + + + ++ +D + C+ + VG ++ + P + P
Sbjct: 282 PRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVVRPRDQIV 341
Query: 323 TGGN-VTLTCQVSGAYPPAKILWLR----NLTQPEVIIQPSSRHLITQDGQNSTLTIHNC 377
G VT C+ G PA + W + NL P QP+SR ++ G LTI N
Sbjct: 342 AQGRTVTFPCETKGNPQPA-VFWQKEGSQNLLFPNQPQQPNSRCSVSPTGD---LTITNI 397
Query: 378 SQDLDEGYYICRADSPVG 395
+ D GYYIC+A + G
Sbjct: 398 QRS-DAGYYICQALTVAG 414
Score = 40.4 bits (93), Expect = 0.004
Identities = 73/293 (24%), Positives = 106/293 (36%), Gaps = 57/293 (19%)
Query: 79 RFSLVDATSLHIESLSLGDEGIYTCQEILNVTQWFQVWLQVASGPYQIEVHIVATGTLPN 138
R+ + D +L I+ DEG Y C V + P Q V P
Sbjct: 285 RYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVVR-------PR 337
Query: 139 GTLYAARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISP----- 193
+ A+G V F C + P P V W S N S +SP
Sbjct: 338 DQI-VAQGRTVTFPCETKGNPQPAVFW---QKEGSQNLLFPNQPQQPNSRCSVSPTGDLT 393
Query: 194 --NLQ----GNYTCLAL----NQLSKRHRKVTTELLVYYPPP---SAPQCWAQMASGSFM 240
N+Q G Y C AL + L+K +V T++L PPP P G+ +
Sbjct: 394 ITNIQRSDAGYYICQALTVAGSILAKAQLEV-TDVLTDRPPPIILQGPANQTLAVDGTAL 452
Query: 241 LQLTCRWDGGYPDPDFLWIEEPGGVIVGK------SKLGVEMLSESQLSDGKKFKCVTSH 294
L+ D P P W++E G G+ + G + ++SD + CV +
Sbjct: 453 LKCKATGD---PLPVISWLKE-GFTFPGRDPRATIQEQGTLQIKNLRISDTGTYTCVATS 508
Query: 295 IVG----------PESGASC-----MVQIRGPSLLSEPMKTCFTGGNVTLTCQ 332
G ESGA+ + + GP S+P T T +VTL+ Q
Sbjct: 509 SSGETSWSAVLDVTESGATISKNYDLSDLPGPP--SKPQVTDVTKNSVTLSWQ 559
>gi|61888896 roundabout, axon guidance receptor, homolog 2 isoform
ROBO2b [Homo sapiens]
Length = 1378
Score = 65.1 bits (157), Expect = 2e-10
Identities = 65/282 (23%), Positives = 119/282 (42%), Gaps = 28/282 (9%)
Query: 144 ARGSQVDFSCNSSSRPPPVVEWWF---QALNSSSESFGHNLTVNFFSLLLI-------SP 193
++G +C + RP P +EW+ + + H + + SL + S
Sbjct: 43 SKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSK 102
Query: 194 NLQGNYTCLALNQLSKR-HRKVTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRWDGGYP 252
+G+Y C+A N L + R + E+ + +A+G + L C+ G+P
Sbjct: 103 PDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAI-LECQPPRGHP 161
Query: 253 DPDFLWIEEPGGVIVGKSKLGVE----MLSESQLSDGKKFKCVTSHIVGP-ESGASCMVQ 307
+P W ++ + + ++ + M+S ++ SD + CV +++VG +S + +
Sbjct: 162 EPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTV 221
Query: 308 IRGPSLLSEPM-KTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQD 366
P+ L P+ + V CQV G P + W ++ P R+ I D
Sbjct: 222 FERPTFLRRPINQVVLEEEAVEFRCQVQGD-PQPTVRWKKDDAD-----LPRGRYDIKDD 275
Query: 367 GQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEP 408
TL I + DEG Y+C A++ VG E L+V+ P
Sbjct: 276 ---YTLRIKK-TMSTDEGTYMCIAENRVGKMEASATLTVRAP 313
Score = 58.2 bits (139), Expect = 2e-08
Identities = 84/378 (22%), Positives = 139/378 (36%), Gaps = 33/378 (8%)
Query: 32 VIGEVHENVTLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSLVDATSLHIE 91
VI E TL+C + WY++ S R P SL +H
Sbjct: 40 VIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGR 99
Query: 92 SLSLGDEGIYTC--QEILNVTQWFQVWLQVASGPYQIEVHIVATGTLPNGT-LYAARGSQ 148
S DEG Y C + L + S +EV ++ N T + A G
Sbjct: 100 R-SKPDEGSYVCVARNYLG---------EAVSRNASLEVALLRDDFRQNPTDVVVAAGEP 149
Query: 149 VDFSCNSS-SRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISPNLQ--GNYTCLALN 205
C P P + W + + +++ L++ + G YTC+ N
Sbjct: 150 AILECQPPRGHPEPTIYWKKDKVRIDDKE--ERISIRGGKLMISNTRKSDAGMYTCVGTN 207
Query: 206 QLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWIEEPGGV 265
+ +R EL V+ P + Q+ ++ C+ G P P W ++ +
Sbjct: 208 MVGERDSD-PAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGD-PQPTVRWKKDDADL 265
Query: 266 IVGKSKLGVEM---LSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSLLSEPMKTCF 322
G+ + + + ++ +D + C+ + VG ++ + P + P
Sbjct: 266 PRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVVRPRDQIV 325
Query: 323 TGGN-VTLTCQVSGAYPPAKILWLR----NLTQPEVIIQPSSRHLITQDGQNSTLTIHNC 377
G VT C+ G PA + W + NL P QP+SR ++ G LTI N
Sbjct: 326 AQGRTVTFPCETKGNPQPA-VFWQKEGSQNLLFPNQPQQPNSRCSVSPTGD---LTITNI 381
Query: 378 SQDLDEGYYICRADSPVG 395
+ D GYYIC+A + G
Sbjct: 382 QRS-DAGYYICQALTVAG 398
Score = 40.4 bits (93), Expect = 0.004
Identities = 73/293 (24%), Positives = 106/293 (36%), Gaps = 57/293 (19%)
Query: 79 RFSLVDATSLHIESLSLGDEGIYTCQEILNVTQWFQVWLQVASGPYQIEVHIVATGTLPN 138
R+ + D +L I+ DEG Y C V + P Q V P
Sbjct: 269 RYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVVR-------PR 321
Query: 139 GTLYAARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLLLISP----- 193
+ A+G V F C + P P V W S N S +SP
Sbjct: 322 DQI-VAQGRTVTFPCETKGNPQPAVFW---QKEGSQNLLFPNQPQQPNSRCSVSPTGDLT 377
Query: 194 --NLQ----GNYTCLAL----NQLSKRHRKVTTELLVYYPPP---SAPQCWAQMASGSFM 240
N+Q G Y C AL + L+K +V T++L PPP P G+ +
Sbjct: 378 ITNIQRSDAGYYICQALTVAGSILAKAQLEV-TDVLTDRPPPIILQGPANQTLAVDGTAL 436
Query: 241 LQLTCRWDGGYPDPDFLWIEEPGGVIVGK------SKLGVEMLSESQLSDGKKFKCVTSH 294
L+ D P P W++E G G+ + G + ++SD + CV +
Sbjct: 437 LKCKATGD---PLPVISWLKE-GFTFPGRDPRATIQEQGTLQIKNLRISDTGTYTCVATS 492
Query: 295 IVG----------PESGASC-----MVQIRGPSLLSEPMKTCFTGGNVTLTCQ 332
G ESGA+ + + GP S+P T T +VTL+ Q
Sbjct: 493 SSGETSWSAVLDVTESGATISKNYDLSDLPGPP--SKPQVTDVTKNSVTLSWQ 543
>gi|4827022 contactin 2 precursor [Homo sapiens]
Length = 1040
Score = 62.8 bits (151), Expect = 8e-10
Identities = 89/364 (24%), Positives = 144/364 (39%), Gaps = 37/364 (10%)
Query: 65 FLLSSNSSLRPAEPRFSLVDAT-SLHIESLSLGDEGIYTCQEI----LNVTQWFQVWLQV 119
+LL+ + P + R + T +L+I + D G Y+C + F + Q+
Sbjct: 168 WLLNEFPNFIPTDGRHFVSQTTGNLYIARTNASDLGNYSCLATSHMDFSTKSVFSKFAQL 227
Query: 120 ASGPYQIEVHIVATGTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGH 179
+ + YA G QV C + P P ++W + S +
Sbjct: 228 NLAAEDTRLFAPSIKARFPAETYALVGQQVTLECFAFGNPVPRIKWRKVDGSLSPQWTTA 287
Query: 180 NLTVNFFSLLLISPNLQGNYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSF 239
T+ S +S +G Y C A N SK V ++V P W ++ S +
Sbjct: 288 EPTLQIPS---VSFEDEGTYECEAEN--SKGRDTVQGRIIVQAQPE-----WLKVISDTE 337
Query: 240 M-LQLTCRWD---GGYPDPDFLWIEEPGGVIVGKSKL----GVEMLSESQLSDGKKFKCV 291
+ RW G P P W+ G + ++++ G S+ L D ++CV
Sbjct: 338 ADIGSNLRWGCAAAGKPRPTVRWLRN-GEPLASQNRVEVLAGDLRFSKLSLEDSGMYQCV 396
Query: 292 TSHIVGP-ESGASCMVQIRGPSLLSEPMKTCF---TGGNVTLTCQVSGAYPPAKILWLRN 347
+ G + A VQ P P++ GG + + CQ A P A +LW +
Sbjct: 397 AENKHGTIYASAELAVQALAPDFRLNPVRRLIPAARGGEILIPCQPRAA-PKAVVLWSKG 455
Query: 348 LTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKE 407
E+++ SSR +T DG TL I N S+ DEG Y C A++ +G LSV++
Sbjct: 456 ---TEILVN-SSRVTVTPDG---TLIIRNISRS-DEGKYTCFAENFMGKANSTGILSVRD 507
Query: 408 PLNI 411
I
Sbjct: 508 ATKI 511
Score = 42.4 bits (98), Expect = 0.001
Identities = 31/90 (34%), Positives = 41/90 (45%), Gaps = 11/90 (12%)
Query: 310 GPSLLSEPMKTCF----TGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQ 365
GP +P+ F T V L C+ A PPA W N T E+ ++P SRH +
Sbjct: 36 GPVFEDQPLSVLFPEESTEEQVLLACRAR-ASPPATYRWKMNGT--EMKLEPGSRHQLV- 91
Query: 366 DGQNSTLTIHNCSQDLDEGYYICRADSPVG 395
L I N ++ D G Y C A +PVG
Sbjct: 92 ---GGNLVIMNPTKAQDAGVYQCLASNPVG 118
Score = 31.6 bits (70), Expect = 1.9
Identities = 30/121 (24%), Positives = 48/121 (39%), Gaps = 10/121 (8%)
Query: 276 MLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSLLS----EPMKTCFTGGNVTLTC 331
+++ ++ D ++C+ S+ VG +++ S +P+K G V L C
Sbjct: 97 IMNPTKAQDAGVYQCLASNPVGTVVSREAILRFGFLQEFSKEERDPVKA-HEGWGVMLPC 155
Query: 332 QVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQDLDEGYYICRAD 391
YP WL L + I RH ++Q N + N S D G Y C A
Sbjct: 156 NPPAHYPGLSYRWL--LNEFPNFIPTDGRHFVSQTTGNLYIARTNAS---DLGNYSCLAT 210
Query: 392 S 392
S
Sbjct: 211 S 211
Score = 29.3 bits (64), Expect = 9.6
Identities = 42/198 (21%), Positives = 77/198 (38%), Gaps = 24/198 (12%)
Query: 64 VFLLSSNSSLRPAEPRFSLVDATSLHIESLSLGDEGIYTCQEILNVTQWFQVWLQVASGP 123
V L S + + R ++ +L I ++S DEG YTC + + ++ A+
Sbjct: 449 VVLWSKGTEILVNSSRVTVTPDGTLIIRNISRSDEGKYTC--------FAENFMGKANST 500
Query: 124 YQIEVHIVATGTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESF----GH 179
+ V TL + G + C++S P + + + L+ F GH
Sbjct: 501 GILSVRDATKITLAPSSADINLGDNLTLQCHASHDPTMDLTFTW-TLDDFPIDFDKPGGH 559
Query: 180 ----NLTVNFFSLLLISPNLQ--GNYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQ 233
N+ L +++ L+ G YTC+A + ++ T ++ PP P
Sbjct: 560 YRRTNVKETIGDLTILNAQLRHGGKYTCMAQTVVDSASKEAT---VLVRGPPGPPGGVVV 616
Query: 234 MASGSFMLQLTCRWDGGY 251
G +QL+ W G+
Sbjct: 617 RDIGDTTIQLS--WSRGF 632
>gi|94420689 neural cell adhesion molecule 1 isoform 1 [Homo
sapiens]
Length = 848
Score = 62.4 bits (150), Expect = 1e-09
Identities = 84/396 (21%), Positives = 140/396 (35%), Gaps = 64/396 (16%)
Query: 38 ENVTLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSLVDATSLHIESLSLGD 97
E+ + C +S L + W + + + RF ++ L I + D
Sbjct: 133 EDAVIVCDVVSSLPPTIIWKHKGRDVIL---------KKDVRFIVLSNNYLQIRGIKKTD 183
Query: 98 EGIYTCQEILNVTQWFQVWLQVASGPYQIEVHIVATGTLPNGTLYAARGSQVDFSCNSSS 157
EG Y C+ + ++ + + I A + N T A G V C++
Sbjct: 184 EGTYRCEG--RILARGEINFKDIQVIVNVPPTIQARQNIVNAT--ANLGQSVTLVCDAEG 239
Query: 158 RPPPVVEWWFQALNSSSESFGHNLTVNFFSLLL----ISPNLQGNYTCLALNQLSKR--- 210
P P + W E + S L + N + Y C+A N+ ++
Sbjct: 240 FPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDAT 299
Query: 211 -HRKVTTE-LLVYYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWIEEPGGVIVG 268
H KV + + Y +A + Q+ LTC G P P W +
Sbjct: 300 IHLKVFAKPKITYVENQTAMELEEQVT-------LTCEASGD-PIPSITWRTSTRNISSE 351
Query: 269 KSKLGVEMLSES------------QLSDGKKFKCVTSHIVGPESGASCMVQIRGPSLLSE 316
+ L M+ S Q +D ++ C S+ +G +S + + P L
Sbjct: 352 EKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGP 411
Query: 317 PMKTCFTGGNVTLTCQVSGAYPPAKILWLR--------NLTQPEVIIQPSSRHL-ITQDG 367
+ G V +TC+V AYP A I W R N + ++ PS+ +L +T D
Sbjct: 412 VAVYTWEGNQVNITCEVF-AYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDS 470
Query: 368 QNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWL 403
+N D G Y C A + +G +E L
Sbjct: 471 EN------------DFGNYNCTAVNRIGQESLEFIL 494
Score = 49.3 bits (116), Expect = 9e-06
Identities = 78/395 (19%), Positives = 146/395 (36%), Gaps = 67/395 (16%)
Query: 54 VTWYRNNSEPVFLLSSNSSLRPAEPRFSLV----DATSLHIESLSLGDEGIYTC------ 103
++W+ N E L P + R S+V +++L I + ++ D GIY C
Sbjct: 52 ISWFSPNGE---------KLTPNQQRISVVWNDDSSSTLTIYNANIDDAGIYKCVVTGED 102
Query: 104 ----QEILNVTQWFQVWLQVASGPYQIEVHIVATGTLPNGTLYAARGSQVDFSCNSSSRP 159
+ +NV + ++ + A P + G C+ S
Sbjct: 103 GSESEATVNVKIFQKLMFKNAPTPQEFR-----------------EGEDAVIVCDVVSSL 145
Query: 160 PPVVEWWFQALNSSSESFGHNLTV--NFFSLLLISPNLQGNYTC----LALNQLSKRHRK 213
PP + W + + + + + N+ + I +G Y C LA +++ + +
Sbjct: 146 PPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQ 205
Query: 214 VTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRWDG-GYPDPDFLWI--------EEPGG 264
V +V PP + A+ + +T D G+P+P W EE
Sbjct: 206 V----IVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDE 261
Query: 265 VIVGKSKLGVEMLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSLLSEPMKTCFT- 323
+ + + +D ++ C+ + G + + P + +T
Sbjct: 262 KYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENQTAMEL 321
Query: 324 GGNVTLTCQVSGAYPPAKILW---LRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQD 380
VTLTC+ SG P I W RN++ E + ++ + S+LT+ + Q
Sbjct: 322 EEQVTLTCEASGD-PIPSITWRTSTRNISSEEKTLD--GHMVVRSHARVSSLTLKSI-QY 377
Query: 381 LDEGYYICRADSPVGVREMEIWLSVKEPLNIGGIV 415
D G YIC A + +G ++L V+ + G V
Sbjct: 378 TDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPV 412
>gi|115529478 neural cell adhesion molecule 1 isoform 3 [Homo
sapiens]
Length = 761
Score = 62.4 bits (150), Expect = 1e-09
Identities = 84/396 (21%), Positives = 140/396 (35%), Gaps = 64/396 (16%)
Query: 38 ENVTLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSLVDATSLHIESLSLGD 97
E+ + C +S L + W + + + RF ++ L I + D
Sbjct: 133 EDAVIVCDVVSSLPPTIIWKHKGRDVIL---------KKDVRFIVLSNNYLQIRGIKKTD 183
Query: 98 EGIYTCQEILNVTQWFQVWLQVASGPYQIEVHIVATGTLPNGTLYAARGSQVDFSCNSSS 157
EG Y C+ + ++ + + I A + N T A G V C++
Sbjct: 184 EGTYRCEG--RILARGEINFKDIQVIVNVPPTIQARQNIVNAT--ANLGQSVTLVCDAEG 239
Query: 158 RPPPVVEWWFQALNSSSESFGHNLTVNFFSLLL----ISPNLQGNYTCLALNQLSKR--- 210
P P + W E + S L + N + Y C+A N+ ++
Sbjct: 240 FPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDAT 299
Query: 211 -HRKVTTE-LLVYYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWIEEPGGVIVG 268
H KV + + Y +A + Q+ LTC G P P W +
Sbjct: 300 IHLKVFAKPKITYVENQTAMELEEQVT-------LTCEASGD-PIPSITWRTSTRNISSE 351
Query: 269 KSKLGVEMLSES------------QLSDGKKFKCVTSHIVGPESGASCMVQIRGPSLLSE 316
+ L M+ S Q +D ++ C S+ +G +S + + P L
Sbjct: 352 EKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGP 411
Query: 317 PMKTCFTGGNVTLTCQVSGAYPPAKILWLR--------NLTQPEVIIQPSSRHL-ITQDG 367
+ G V +TC+V AYP A I W R N + ++ PS+ +L +T D
Sbjct: 412 VAVYTWEGNQVNITCEVF-AYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDS 470
Query: 368 QNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWL 403
+N D G Y C A + +G +E L
Sbjct: 471 EN------------DFGNYNCTAVNRIGQESLEFIL 494
Score = 49.3 bits (116), Expect = 9e-06
Identities = 78/395 (19%), Positives = 146/395 (36%), Gaps = 67/395 (16%)
Query: 54 VTWYRNNSEPVFLLSSNSSLRPAEPRFSLV----DATSLHIESLSLGDEGIYTC------ 103
++W+ N E L P + R S+V +++L I + ++ D GIY C
Sbjct: 52 ISWFSPNGE---------KLTPNQQRISVVWNDDSSSTLTIYNANIDDAGIYKCVVTGED 102
Query: 104 ----QEILNVTQWFQVWLQVASGPYQIEVHIVATGTLPNGTLYAARGSQVDFSCNSSSRP 159
+ +NV + ++ + A P + G C+ S
Sbjct: 103 GSESEATVNVKIFQKLMFKNAPTPQEFR-----------------EGEDAVIVCDVVSSL 145
Query: 160 PPVVEWWFQALNSSSESFGHNLTV--NFFSLLLISPNLQGNYTC----LALNQLSKRHRK 213
PP + W + + + + + N+ + I +G Y C LA +++ + +
Sbjct: 146 PPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQ 205
Query: 214 VTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRWDG-GYPDPDFLWI--------EEPGG 264
V +V PP + A+ + +T D G+P+P W EE
Sbjct: 206 V----IVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDE 261
Query: 265 VIVGKSKLGVEMLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSLLSEPMKTCFT- 323
+ + + +D ++ C+ + G + + P + +T
Sbjct: 262 KYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENQTAMEL 321
Query: 324 GGNVTLTCQVSGAYPPAKILW---LRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQD 380
VTLTC+ SG P I W RN++ E + ++ + S+LT+ + Q
Sbjct: 322 EEQVTLTCEASGD-PIPSITWRTSTRNISSEEKTLD--GHMVVRSHARVSSLTLKSI-QY 377
Query: 381 LDEGYYICRADSPVGVREMEIWLSVKEPLNIGGIV 415
D G YIC A + +G ++L V+ + G V
Sbjct: 378 TDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPV 412
>gi|7657361 contactin 6 [Homo sapiens]
Length = 1028
Score = 61.6 bits (148), Expect = 2e-09
Identities = 88/374 (23%), Positives = 152/374 (40%), Gaps = 61/374 (16%)
Query: 60 NSEPVFLLSSNSSLRPAEPRFSLVDATSLHIESLSLGDEGIYTC----QEILNVTQWFQV 115
N P+++ N RF + +L+I + D G YTC +E Q
Sbjct: 160 NDNPLYVQEDNR-------RFVSQETGNLYIAKVEPSDVGNYTCFITNKEAQRSVQGPPT 212
Query: 116 WLQVAS----GPYQIEVHIVATGTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWWFQALN 171
L + G Y+ ++ + P T+ AA+ S V C + P P + W + L+
Sbjct: 213 PLVQRTDGVMGEYEPKIEV----RFPE-TIQAAKDSSVKLECFALGNPVPDISW--RRLD 265
Query: 172 SSSESFGHNLTVNFFSLLLISPNLQ----GNYTCLALNQLSKRHRKVTTELLVYYPPPSA 227
S + + +L PN Q G Y C+A N R R + L++Y PP
Sbjct: 266 GS--PLPGKVKYSKSQAILEIPNFQQEDEGFYECIASN---LRGRNLAKGQLIFYAPPE- 319
Query: 228 PQCWAQMASGSFM-LQLTCRWD---GGYPDPDFLWIEEPGGVIVGKSKLGVE----MLSE 279
W Q + + + W+ G P+P + W++ G + + ++ +E +++
Sbjct: 320 ---WEQKIQNTHLSIYDNLLWECKASGKPNPWYTWLKN-GERLNPEERIQIENGTLIITM 375
Query: 280 SQLSDGKKFKCVTSH---IVGPESGASCMVQIRGPSLLSEPMKT---CFTGGNVTLTCQV 333
+SD ++C + I+ + A V P P+K GG++ + C+
Sbjct: 376 LNVSDSGVYQCAAENKYQII--YANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCK- 432
Query: 334 SGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQDLDEGYYICRADSP 393
A+P A I W R ++ S R + +DG +L I+N ++ D G Y C A +
Sbjct: 433 PNAFPRAAISWKRGTE----TLRQSKRIFLLEDG---SLKIYNITRS-DAGSYTCIATNQ 484
Query: 394 VGVREMEIWLSVKE 407
G + L VKE
Sbjct: 485 FGTAKNTGSLIVKE 498
>gi|19743806 roundabout 1 isoform b [Homo sapiens]
Length = 1612
Score = 61.2 bits (147), Expect = 2e-09
Identities = 67/286 (23%), Positives = 118/286 (41%), Gaps = 30/286 (10%)
Query: 141 LYAARGSQVDFSCNSSSRPPPVVEWW---FQALNSSSESFGHNLTVNFFSLLLI------ 191
L ++G +C + RP P +EW+ + + H + + SL +
Sbjct: 38 LIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGR 97
Query: 192 -SPNLQGNYTCLALNQLSKR-HRKVTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRWDG 249
S +G Y C+A N L + + E+ + +A G + + C+
Sbjct: 98 KSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAV-MECQPPR 156
Query: 250 GYPDPDFLWIEEPGGVIVGKSKL-----GVEMLSESQLSDGKKFKCVTSHIVGP-ESGAS 303
G+P+P W ++ G + K + G M++ ++ SD K+ CV +++VG ES +
Sbjct: 157 GHPEPTISW-KKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVA 215
Query: 304 CMVQIRGPSLLSEPMKTCFT-GGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHL 362
+ + PS + P T + C+ G P + W ++ + P SR+
Sbjct: 216 ELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGD-PVPTVRWRKDDGE-----LPKSRYE 269
Query: 363 ITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEP 408
I D TL I + D G Y C A++ VG E L+V+EP
Sbjct: 270 IRDD---HTLKIRKVTAG-DMGSYTCVAENMVGKAEASATLTVQEP 311
Score = 49.3 bits (116), Expect = 9e-06
Identities = 75/307 (24%), Positives = 124/307 (40%), Gaps = 58/307 (18%)
Query: 79 RFSLVDATSLHIESLSLGDEGIYTC-QEILNVTQWFQVWLQVASGPYQIEVHIVATGTLP 137
R+ + D +L I ++ GD G YTC E + L V P+ + P
Sbjct: 267 RYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFV--------VKP 318
Query: 138 NGTLYAARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLL----LISP 193
+ A G V F C ++ P P + W + + S+ + + FS+ L
Sbjct: 319 RDQV-VALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTIT 377
Query: 194 NLQ----GNYTCLALNQ----LSKRHRKVTTELLVYYPPP---SAPQCWAQMASGSFMLQ 242
N+Q G Y C LN ++K + +V T+++ PPP P G+F+L
Sbjct: 378 NVQRSDVGYYICQTLNVAGSIITKAYLEV-TDVIADRPPPVIRQGPVNQTVAVDGTFVLS 436
Query: 243 LTCRWDGGYPDPDFLWIEEPGGVIVG-------KSKLGVEMLSESQLSDGKKFKCVTSHI 295
G P P LW ++ GV+V + + GV + ++L D ++ C+ S
Sbjct: 437 CVAT---GSPVPTILWRKD--GVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTP 491
Query: 296 VGPESGASCMVQIRG----------------PSLLSEPMKTCFTGGNVTLTCQV---SGA 336
G E+ S ++++ PS S+P T + VTL+ Q SGA
Sbjct: 492 SG-EATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGA 550
Query: 337 YPPAKIL 343
P + I+
Sbjct: 551 TPTSYII 557
Score = 42.4 bits (98), Expect = 0.001
Identities = 61/279 (21%), Positives = 105/279 (37%), Gaps = 35/279 (12%)
Query: 150 DFSCNSSSRPPPVVEWWFQ--ALNSSSESFGHNLTVNFFSLLLISPNLQGNYTCLALNQL 207
+F C + P P V W L S + T+ + ++ G+YTC+A N +
Sbjct: 241 EFKCEARGDPVPTVRWRKDDGELPKSRYEIRDDHTLK---IRKVTAGDMGSYTCVAENMV 297
Query: 208 SKRHRKVTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWIEEPGGVIV 267
K T L V PP + Q+ + + C G P P W E ++
Sbjct: 298 GKAEASAT--LTVQEPPHFVVKPRDQVVALGRTVTFQCEATGN-PQPAIFWRREGSQNLL 354
Query: 268 ------------GKSKLGVEMLSESQLSDGKKFKCVTSHIVGPESGASCM-----VQIRG 310
S+ G ++ Q SD + C T ++ G + + + R
Sbjct: 355 FSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRP 414
Query: 311 PSLLSE-PM-KTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQ 368
P ++ + P+ +T G L+C +G+ P ILW ++ V++ + + +
Sbjct: 415 PPVIRQGPVNQTVAVDGTFVLSCVATGS-PVPTILWRKD----GVLVSTQDSRI--KQLE 467
Query: 369 NSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKE 407
N L I D G Y C A +P G ++ V+E
Sbjct: 468 NGVLQIRYAKLG-DTGRYTCIASTPSGEATWSAYIEVQE 505
>gi|4506569 roundabout 1 isoform a [Homo sapiens]
Length = 1651
Score = 61.2 bits (147), Expect = 2e-09
Identities = 67/286 (23%), Positives = 118/286 (41%), Gaps = 30/286 (10%)
Query: 141 LYAARGSQVDFSCNSSSRPPPVVEWW---FQALNSSSESFGHNLTVNFFSLLLI------ 191
L ++G +C + RP P +EW+ + + H + + SL +
Sbjct: 77 LIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGR 136
Query: 192 -SPNLQGNYTCLALNQLSKR-HRKVTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRWDG 249
S +G Y C+A N L + + E+ + +A G + + C+
Sbjct: 137 KSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAV-MECQPPR 195
Query: 250 GYPDPDFLWIEEPGGVIVGKSKL-----GVEMLSESQLSDGKKFKCVTSHIVGP-ESGAS 303
G+P+P W ++ G + K + G M++ ++ SD K+ CV +++VG ES +
Sbjct: 196 GHPEPTISW-KKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVA 254
Query: 304 CMVQIRGPSLLSEPMKTCFT-GGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHL 362
+ + PS + P T + C+ G P + W ++ + P SR+
Sbjct: 255 ELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGD-PVPTVRWRKDDGE-----LPKSRYE 308
Query: 363 ITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEP 408
I D TL I + D G Y C A++ VG E L+V+EP
Sbjct: 309 IRDD---HTLKIRKVTAG-DMGSYTCVAENMVGKAEASATLTVQEP 350
Score = 49.3 bits (116), Expect = 9e-06
Identities = 75/307 (24%), Positives = 124/307 (40%), Gaps = 58/307 (18%)
Query: 79 RFSLVDATSLHIESLSLGDEGIYTC-QEILNVTQWFQVWLQVASGPYQIEVHIVATGTLP 137
R+ + D +L I ++ GD G YTC E + L V P+ + P
Sbjct: 306 RYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFV--------VKP 357
Query: 138 NGTLYAARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGHNLTVNFFSLL----LISP 193
+ A G V F C ++ P P + W + + S+ + + FS+ L
Sbjct: 358 RDQV-VALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTIT 416
Query: 194 NLQ----GNYTCLALNQ----LSKRHRKVTTELLVYYPPP---SAPQCWAQMASGSFMLQ 242
N+Q G Y C LN ++K + +V T+++ PPP P G+F+L
Sbjct: 417 NVQRSDVGYYICQTLNVAGSIITKAYLEV-TDVIADRPPPVIRQGPVNQTVAVDGTFVLS 475
Query: 243 LTCRWDGGYPDPDFLWIEEPGGVIVG-------KSKLGVEMLSESQLSDGKKFKCVTSHI 295
G P P LW ++ GV+V + + GV + ++L D ++ C+ S
Sbjct: 476 CVAT---GSPVPTILWRKD--GVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTP 530
Query: 296 VGPESGASCMVQIRG----------------PSLLSEPMKTCFTGGNVTLTCQV---SGA 336
G E+ S ++++ PS S+P T + VTL+ Q SGA
Sbjct: 531 SG-EATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGA 589
Query: 337 YPPAKIL 343
P + I+
Sbjct: 590 TPTSYII 596
Score = 42.4 bits (98), Expect = 0.001
Identities = 61/279 (21%), Positives = 105/279 (37%), Gaps = 35/279 (12%)
Query: 150 DFSCNSSSRPPPVVEWWFQ--ALNSSSESFGHNLTVNFFSLLLISPNLQGNYTCLALNQL 207
+F C + P P V W L S + T+ + ++ G+YTC+A N +
Sbjct: 280 EFKCEARGDPVPTVRWRKDDGELPKSRYEIRDDHTLK---IRKVTAGDMGSYTCVAENMV 336
Query: 208 SKRHRKVTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWIEEPGGVIV 267
K T L V PP + Q+ + + C G P P W E ++
Sbjct: 337 GKAEASAT--LTVQEPPHFVVKPRDQVVALGRTVTFQCEATGN-PQPAIFWRREGSQNLL 393
Query: 268 ------------GKSKLGVEMLSESQLSDGKKFKCVTSHIVGPESGASCM-----VQIRG 310
S+ G ++ Q SD + C T ++ G + + + R
Sbjct: 394 FSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRP 453
Query: 311 PSLLSE-PM-KTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSSRHLITQDGQ 368
P ++ + P+ +T G L+C +G+ P ILW ++ V++ + + +
Sbjct: 454 PPVIRQGPVNQTVAVDGTFVLSCVATGS-PVPTILWRKD----GVLVSTQDSRI--KQLE 506
Query: 369 NSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKE 407
N L I D G Y C A +P G ++ V+E
Sbjct: 507 NGVLQIRYAKLG-DTGRYTCIASTPSGEATWSAYIEVQE 544
>gi|45594240 limbic system-associated membrane protein [Homo
sapiens]
Length = 338
Score = 60.1 bits (144), Expect = 5e-09
Identities = 81/309 (26%), Positives = 128/309 (41%), Gaps = 45/309 (14%)
Query: 10 PRVLVCLGALLAGWVAVGLEAVVIGEVHENVTLHCGNISGLR-------GQVTWYRNNSE 62
P VL+ L LL + V +V +N+T+ G+ + LR +V W N S
Sbjct: 13 PLVLLRLLCLLPTGLPV--RSVDFNRGTDNITVRQGDTAILRCVVEDKNSKVAWL-NRSG 69
Query: 63 PVFLLSSNSSLRPA---EPRFSLVDATSLHIESLSLGDEGIYTCQ-EILNVTQWFQVWLQ 118
+F SL P E R SL SL I+ + + DEG YTC + + + QV+L
Sbjct: 70 IIFAGHDKWSLDPRVELEKRHSL--EYSLRIQKVDVYDEGSYTCSVQTQHEPKTSQVYLI 127
Query: 119 VASGPYQIEVHIVATGTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFG 178
V P ++ +++ N GS V C ++ RP PV+ W + L + F
Sbjct: 128 VQVPP---KISNISSDVTVN------EGSNVTLVCMANGRPEPVITW--RHLTPTGREFE 176
Query: 179 HNLTVNFFSLLLISPNLQGNYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGS 238
+ +L I+ G Y C A N++S K + Y PP+ + + A+
Sbjct: 177 GE--EEYLEILGITREQSGKYECKAANEVSSADVKQVKVTVNY--PPTITESKSNEATTG 232
Query: 239 FMLQLTCRWDGGYPDPDFLW------IEEPGGVIV----GKSKLGVEMLSESQLSDGKKF 288
L C P PDF W I G+ + G+S L V ++E + +
Sbjct: 233 RQASLKCE-ASAVPAPDFEWYRDDTRINSANGLEIKSTEGQSSLTVTNVTEEHYGN---Y 288
Query: 289 KCVTSHIVG 297
CV ++ +G
Sbjct: 289 TCVAANKLG 297
>gi|148886752 immunoglobulin superfamily, member 9B [Homo sapiens]
Length = 1349
Score = 59.3 bits (142), Expect = 9e-09
Identities = 81/337 (24%), Positives = 132/337 (39%), Gaps = 34/337 (10%)
Query: 32 VIGEVHENVTLHCGNISGLRGQ-----VTWYRNNSEPVFLLSSNSSLRPAEPRF----SL 82
V E+V L C I + GQ V W++ + +P + SL
Sbjct: 33 VTARAGESVVLRCDVIHPVTGQPPPYVVEWFKFGVPIPIFIKFGYYPPHVDPEYAGRASL 92
Query: 83 VDATSLHIESLSLGDEGIYTCQEILNVTQWFQVWLQVASGPYQIEVHIVATGTLPNGTLY 142
D SL +E + D+G Y C ++L + Q + + + I T T P +
Sbjct: 93 HDKASLRLEQVRSEDQGWYEC-KVLMLDQQYDTFHNGSWVHLTINAPPTFTETPPQ-YIE 150
Query: 143 AARGSQVDFSCNSSSRPPPVVEWWFQA--LNSSSESFGHNLTVNFFSLLLISPNLQGNYT 200
A G + +C + P P+V W + L +S + + ++ ++ +S +G YT
Sbjct: 151 AKEGGSITMTCTAFGNPKPIVTWLKEGTLLGASGK---YQVSDGSLTVTSVSREDRGAYT 207
Query: 201 CLALN-QLSKRHRKVTTELLVYYPP--PSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFL 257
C A + Q H TT LLV PP S P+ S + LTCR + + +
Sbjct: 208 CRAYSIQGEAVH---TTHLLVQGPPFIVSPPENITVNISQDAL--LTCRAEAYPGNLTYT 262
Query: 258 WIEEPGGVIVGKS-KLGVEMLSESQL-------SDGKKFKCVTSHIVGPESGASCMVQIR 309
W + V KL V +L + L D K+ CV S+ +G AS + ++
Sbjct: 263 WYWQDENVYFQNDLKLRVRILIDGTLIIFRVKPEDSGKYTCVPSNSLGRSPSASAYLTVQ 322
Query: 310 GPS--LLSEPMKTCFTGGNVTLTCQVSGAYPPAKILW 344
P+ L P+ G + + C V P + W
Sbjct: 323 YPARVLNMPPVIYVPVGIHGYIRCPVDAEPPATVVKW 359
>gi|115529482 neural cell adhesion molecule 1 isoform 2 [Homo
sapiens]
Length = 858
Score = 58.9 bits (141), Expect = 1e-08
Identities = 87/406 (21%), Positives = 143/406 (35%), Gaps = 74/406 (18%)
Query: 38 ENVTLHCGNISGLRGQVTWYRNNSEPVFLLSSNSSLRPAEPRFSLVDATSLHIESLSLGD 97
E+ + C +S L + W + + + RF ++ L I + D
Sbjct: 133 EDAVIVCDVVSSLPPTIIWKHKGRDVIL---------KKDVRFIVLSNNYLQIRGIKKTD 183
Query: 98 EGIYTCQEILNVTQWFQVWLQVASGPYQIEVHIVATGTLPNGTLYAARGSQVDFSCNSSS 157
EG Y C+ + ++ + + I A + N T A G V C++
Sbjct: 184 EGTYRCEG--RILARGEINFKDIQVIVNVPPTIQARQNIVNAT--ANLGQSVTLVCDAEG 239
Query: 158 RPPPVVEWWFQALNSSSESFGHNLTVNFFSLLL----ISPNLQGNYTCLALNQLSKR--- 210
P P + W E + S L + N + Y C+A N+ ++
Sbjct: 240 FPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDAT 299
Query: 211 -HRKVTTE-LLVYYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWI--------- 259
H KV + + Y +A + Q+ LTC G P P W
Sbjct: 300 IHLKVFAKPKITYVENQTAMELEEQVT-------LTCEASGD-PIPSITWRTSTRNISSE 351
Query: 260 -----------EEPGGVIVGKSKLGVEMLS--ESQLSDGKKFKCVTSHIVGPESGASCMV 306
E G +V +S V L+ Q +D ++ C S+ +G +S + +
Sbjct: 352 EKASWTRPEKQETLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLE 411
Query: 307 QIRGPSLLSEPMKTCFTGGNVTLTCQVSGAYPPAKILWLR--------NLTQPEVIIQPS 358
P L + G V +TC+V AYP A I W R N + ++ PS
Sbjct: 412 VQYAPKLQGPVAVYTWEGNQVNITCEVF-AYPSATISWFRDGQLLPSSNYSNIKIYNTPS 470
Query: 359 SRHL-ITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWL 403
+ +L +T D +N D G Y C A + +G +E L
Sbjct: 471 ASYLEVTPDSEN------------DFGNYNCTAVNRIGQESLEFIL 504
Score = 47.8 bits (112), Expect = 3e-05
Identities = 80/403 (19%), Positives = 147/403 (36%), Gaps = 73/403 (18%)
Query: 54 VTWYRNNSEPVFLLSSNSSLRPAEPRFSLV----DATSLHIESLSLGDEGIYTC------ 103
++W+ N E L P + R S+V +++L I + ++ D GIY C
Sbjct: 52 ISWFSPNGE---------KLTPNQQRISVVWNDDSSSTLTIYNANIDDAGIYKCVVTGED 102
Query: 104 ----QEILNVTQWFQVWLQVASGPYQIEVHIVATGTLPNGTLYAARGSQVDFSCNSSSRP 159
+ +NV + ++ + A P + G C+ S
Sbjct: 103 GSESEATVNVKIFQKLMFKNAPTPQEFR-----------------EGEDAVIVCDVVSSL 145
Query: 160 PPVVEWWFQALNSSSESFGHNLTV--NFFSLLLISPNLQGNYTC----LALNQLSKRHRK 213
PP + W + + + + + N+ + I +G Y C LA +++ + +
Sbjct: 146 PPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQ 205
Query: 214 VTTELLVYYPPPSAPQCWAQMASGSFMLQLTCRWDG-GYPDPDFLWI--------EEPGG 264
V +V PP + A+ + +T D G+P+P W EE
Sbjct: 206 V----IVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDE 261
Query: 265 VIVGKSKLGVEMLSESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSLLSEPMKTCFT- 323
+ + + +D ++ C+ + G + + P + +T
Sbjct: 262 KYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENQTAMEL 321
Query: 324 GGNVTLTCQVSGAYPPAKILW---LRNL--------TQPEVIIQPSSRHLITQDGQNSTL 372
VTLTC+ SG P I W RN+ T+PE ++ + S+L
Sbjct: 322 EEQVTLTCEASGD-PIPSITWRTSTRNISSEEKASWTRPEKQETLDGHMVVRSHARVSSL 380
Query: 373 TIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEPLNIGGIV 415
T+ + Q D G YIC A + +G ++L V+ + G V
Sbjct: 381 TLKSI-QYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPV 422
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.134 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,941,264
Number of Sequences: 37866
Number of extensions: 1212779
Number of successful extensions: 22954
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 410
Number of HSP's successfully gapped in prelim test: 479
Number of HSP's that attempted gapping in prelim test: 11725
Number of HSP's gapped (non-prelim): 6527
length of query: 540
length of database: 18,247,518
effective HSP length: 107
effective length of query: 433
effective length of database: 14,195,856
effective search space: 6146805648
effective search space used: 6146805648
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.