Search of human proteins with 125625350

Search of human proteins with 125625350

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|125625350 cell division cycle 25C isoform a [Homo sapiens]
         (473 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|125625350 cell division cycle 25C isoform a [Homo sapiens]         963   0.0  
gi|12408658 cell division cycle 25C isoform b [Homo sapiens]          660   0.0  
gi|11641413 cell division cycle 25B isoform 1 [Homo sapiens]          265   9e-71
gi|11641411 cell division cycle 25B isoform 3 [Homo sapiens]          265   9e-71
gi|4757950 cell division cycle 25B isoform 2 [Homo sapiens]           265   9e-71
gi|42490760 cell division cycle 25A isoform b [Homo sapiens]          262   6e-70
gi|42490758 cell division cycle 25A isoform a [Homo sapiens]          255   5e-68
gi|95147555 microtubule-associated protein 1A [Homo sapiens]           36   0.087
gi|7019493 DNA-directed DNA polymerase mu [Homo sapiens]               34   0.25 
gi|62865890 dual specificity phosphatase 5 [Homo sapiens]              34   0.33 
gi|34328899 protein tyrosine phosphatase, non-receptor type 14 [...    33   0.56 
gi|148806928 hypothetical protein LOC57482 [Homo sapiens]              33   0.73 
gi|54792136 follistatin-like 4 [Homo sapiens]                          32   0.96 
gi|217035118 TBC1 domain family, member 23 [Homo sapiens]              32   1.6  
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ...    31   2.8  
gi|154146191 heat shock 90kDa protein 1, alpha isoform 2 [Homo s...    30   3.6  
gi|153792590 heat shock 90kDa protein 1, alpha isoform 1 [Homo s...    30   3.6  
gi|20149594 heat shock 90kDa protein 1, beta [Homo sapiens]            30   3.6  
gi|90652857 hypothetical protein LOC84904 [Homo sapiens]               30   3.6  
gi|4885579 RCD1 required for cell differentiation1 homolog [Homo...    30   6.2  
gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens]     30   6.2  
gi|22095388 islet cell autoantigen 1,69kDa-like isoform 1 [Homo ...    30   6.2  
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    29   8.1  

>gi|125625350 cell division cycle 25C isoform a [Homo sapiens]
          Length = 473

 Score =  963 bits (2489), Expect = 0.0
 Identities = 473/473 (100%), Positives = 473/473 (100%)

Query: 1   MSTELFSSTREEGSSGSGPSFRSNQRKMLNLLLERDTSFTVCPDVPRTPVGKFLGDSANL 60
           MSTELFSSTREEGSSGSGPSFRSNQRKMLNLLLERDTSFTVCPDVPRTPVGKFLGDSANL
Sbjct: 1   MSTELFSSTREEGSSGSGPSFRSNQRKMLNLLLERDTSFTVCPDVPRTPVGKFLGDSANL 60

Query: 61  SILSGGTPKRCLDLSNLSSGEITATQLTTSADLDETGHLDSSGLQEVHLAGMNHDQHLMK 120
           SILSGGTPKRCLDLSNLSSGEITATQLTTSADLDETGHLDSSGLQEVHLAGMNHDQHLMK
Sbjct: 61  SILSGGTPKRCLDLSNLSSGEITATQLTTSADLDETGHLDSSGLQEVHLAGMNHDQHLMK 120

Query: 121 CSPAQLLCSTPNGLDRGHRKRDAMCSSSANKENDNGNLVDSEMKYLGSPITTVPKLDKNP 180
           CSPAQLLCSTPNGLDRGHRKRDAMCSSSANKENDNGNLVDSEMKYLGSPITTVPKLDKNP
Sbjct: 121 CSPAQLLCSTPNGLDRGHRKRDAMCSSSANKENDNGNLVDSEMKYLGSPITTVPKLDKNP 180

Query: 181 NLGEDQAEEISDELMEFSLKDQEAKVSRSGLYRSPSMPENLNRPRLKQVEKFKDNTIPDK 240
           NLGEDQAEEISDELMEFSLKDQEAKVSRSGLYRSPSMPENLNRPRLKQVEKFKDNTIPDK
Sbjct: 181 NLGEDQAEEISDELMEFSLKDQEAKVSRSGLYRSPSMPENLNRPRLKQVEKFKDNTIPDK 240

Query: 241 VKKKYFSGQGKLRKGLCLKKTVSLCDITITQMLEEDSNQGHLIGDFSKVCALPTVSGKHQ 300
           VKKKYFSGQGKLRKGLCLKKTVSLCDITITQMLEEDSNQGHLIGDFSKVCALPTVSGKHQ
Sbjct: 241 VKKKYFSGQGKLRKGLCLKKTVSLCDITITQMLEEDSNQGHLIGDFSKVCALPTVSGKHQ 300

Query: 301 DLKYVNPETVAALLSGKFQGLIEKFYVIDCRYPYEYLGGHIQGALNLYSQEELFNFFLKK 360
           DLKYVNPETVAALLSGKFQGLIEKFYVIDCRYPYEYLGGHIQGALNLYSQEELFNFFLKK
Sbjct: 301 DLKYVNPETVAALLSGKFQGLIEKFYVIDCRYPYEYLGGHIQGALNLYSQEELFNFFLKK 360

Query: 361 PIVPLDTQKRIIIVFHCEFSSERGPRMCRCLREEDRSLNQYPALYYPELYILKGGYRDFF 420
           PIVPLDTQKRIIIVFHCEFSSERGPRMCRCLREEDRSLNQYPALYYPELYILKGGYRDFF
Sbjct: 361 PIVPLDTQKRIIIVFHCEFSSERGPRMCRCLREEDRSLNQYPALYYPELYILKGGYRDFF 420

Query: 421 PEYMELCEPQSYCPMHHQDHKTELLRCRSQSKVQEGERQLREQIALLVKDMSP 473
           PEYMELCEPQSYCPMHHQDHKTELLRCRSQSKVQEGERQLREQIALLVKDMSP
Sbjct: 421 PEYMELCEPQSYCPMHHQDHKTELLRCRSQSKVQEGERQLREQIALLVKDMSP 473


>gi|12408658 cell division cycle 25C isoform b [Homo sapiens]
          Length = 400

 Score =  660 bits (1703), Expect = 0.0
 Identities = 323/328 (98%), Positives = 324/328 (98%)

Query: 146 SSSANKENDNGNLVDSEMKYLGSPITTVPKLDKNPNLGEDQAEEISDELMEFSLKDQEAK 205
           S SA   +DNGNLVDSEMKYLGSPITTVPKLDKNPNLGEDQAEEISDELMEFSLKDQEAK
Sbjct: 73  SGSAFSWDDNGNLVDSEMKYLGSPITTVPKLDKNPNLGEDQAEEISDELMEFSLKDQEAK 132

Query: 206 VSRSGLYRSPSMPENLNRPRLKQVEKFKDNTIPDKVKKKYFSGQGKLRKGLCLKKTVSLC 265
           VSRSGLYRSPSMPENLNRPRLKQVEKFKDNTIPDKVKKKYFSGQGKLRKGLCLKKTVSLC
Sbjct: 133 VSRSGLYRSPSMPENLNRPRLKQVEKFKDNTIPDKVKKKYFSGQGKLRKGLCLKKTVSLC 192

Query: 266 DITITQMLEEDSNQGHLIGDFSKVCALPTVSGKHQDLKYVNPETVAALLSGKFQGLIEKF 325
           DITITQMLEEDSNQGHLIGDFSKVCALPTVSGKHQDLKYVNPETVAALLSGKFQGLIEKF
Sbjct: 193 DITITQMLEEDSNQGHLIGDFSKVCALPTVSGKHQDLKYVNPETVAALLSGKFQGLIEKF 252

Query: 326 YVIDCRYPYEYLGGHIQGALNLYSQEELFNFFLKKPIVPLDTQKRIIIVFHCEFSSERGP 385
           YVIDCRYPYEYLGGHIQGALNLYSQEELFNFFLKKPIVPLDTQKRIIIVFHCEFSSERGP
Sbjct: 253 YVIDCRYPYEYLGGHIQGALNLYSQEELFNFFLKKPIVPLDTQKRIIIVFHCEFSSERGP 312

Query: 386 RMCRCLREEDRSLNQYPALYYPELYILKGGYRDFFPEYMELCEPQSYCPMHHQDHKTELL 445
           RMCRCLREEDRSLNQYPALYYPELYILKGGYRDFFPEYMELCEPQSYCPMHHQDHKTELL
Sbjct: 313 RMCRCLREEDRSLNQYPALYYPELYILKGGYRDFFPEYMELCEPQSYCPMHHQDHKTELL 372

Query: 446 RCRSQSKVQEGERQLREQIALLVKDMSP 473
           RCRSQSKVQEGERQLREQIALLVKDMSP
Sbjct: 373 RCRSQSKVQEGERQLREQIALLVKDMSP 400



 Score =  134 bits (336), Expect = 2e-31
 Identities = 76/117 (64%), Positives = 84/117 (71%), Gaps = 10/117 (8%)

Query: 1   MSTELFSSTREEGSSGSGPSFRSNQRKMLNLLLERDTSFTVCPDVPRTPVGKFLGDSANL 60
           MSTELFSSTREEGSSGSGPSFRSNQRKMLNLLLERDTSFTVCPDVPRTPVGKFLGDSANL
Sbjct: 1   MSTELFSSTREEGSSGSGPSFRSNQRKMLNLLLERDTSFTVCPDVPRTPVGKFLGDSANL 60

Query: 61  SILSG--------GTPKRCLDLSNLSSGEI--TATQLTTSADLDETGHLDSSGLQEV 107
           SILSG        G+     D  NL   E+    + +TT   LD+  +L     +E+
Sbjct: 61  SILSGSPGFFRTSGSAFSWDDNGNLVDSEMKYLGSPITTVPKLDKNPNLGEDQAEEI 117


>gi|11641413 cell division cycle 25B isoform 1 [Homo sapiens]
          Length = 580

 Score =  265 bits (676), Expect = 9e-71
 Identities = 143/330 (43%), Positives = 208/330 (63%), Gaps = 20/330 (6%)

Query: 141 RDAMCSSSANKENDNG--NLVDSEMKYLGSPITTVPKLDKNPNLGEDQAEEISDELMEFS 198
           R ++  +  + E D+G  ++++S++K   +    +  L   P +   + EE  D +M   
Sbjct: 255 RFSLTPAEGDTEEDDGFVDILESDLKDDDAVPPGMESLISAPLVKTLEKEEEKDLVMY-- 312

Query: 199 LKDQEAKVSRSGLYRSPSMPENLNRPRLKQVEKFKDNTIPDKVKKKYF------SGQGKL 252
                +K  R  L+RSPSMP ++ RP LK++E+ +D   P + K++          + + 
Sbjct: 313 -----SKCQR--LFRSPSMPCSVIRPILKRLERPQDRDTPVQNKRRRSVTPPEEQQEAEE 365

Query: 253 RKGLCLKKTVSLCDITITQMLEEDSNQGHLIGDFSKVCALPTVSGKHQDLKYVNPETVAA 312
            K   L+   SLC   I  +L+ D  +  LIGD+SK   L TV GKHQDLKY++PET+ A
Sbjct: 366 PKARVLRSK-SLCHDEIENLLDSDHRE--LIGDYSKAFLLQTVDGKHQDLKYISPETMVA 422

Query: 313 LLSGKFQGLIEKFYVIDCRYPYEYLGGHIQGALNLYSQEELFNFFLKKPIVPLDTQKRII 372
           LL+GKF  +++KF ++DCRYPYEY GGHI+ A+NL  + +  +F LK PI P    KR+I
Sbjct: 423 LLTGKFSNIVDKFVIVDCRYPYEYEGGHIKTAVNLPLERDAESFLLKSPIAPCSLDKRVI 482

Query: 373 IVFHCEFSSERGPRMCRCLREEDRSLNQYPALYYPELYILKGGYRDFFPEYMELCEPQSY 432
           ++FHCEFSSERGPRMCR +RE DR++N YP+LYYPE+YILKGGY++FFP++   CEPQ Y
Sbjct: 483 LIFHCEFSSERGPRMCRFIRERDRAVNDYPSLYYPEMYILKGGYKEFFPQHPNFCEPQDY 542

Query: 433 CPMHHQDHKTELLRCRSQSKVQEGERQLRE 462
            PM+H+  K EL   R +++   GER  RE
Sbjct: 543 RPMNHEAFKDELKTFRLKTRSWAGERSRRE 572


>gi|11641411 cell division cycle 25B isoform 3 [Homo sapiens]
          Length = 539

 Score =  265 bits (676), Expect = 9e-71
 Identities = 143/330 (43%), Positives = 208/330 (63%), Gaps = 20/330 (6%)

Query: 141 RDAMCSSSANKENDNG--NLVDSEMKYLGSPITTVPKLDKNPNLGEDQAEEISDELMEFS 198
           R ++  +  + E D+G  ++++S++K   +    +  L   P +   + EE  D +M   
Sbjct: 214 RFSLTPAEGDTEEDDGFVDILESDLKDDDAVPPGMESLISAPLVKTLEKEEEKDLVMY-- 271

Query: 199 LKDQEAKVSRSGLYRSPSMPENLNRPRLKQVEKFKDNTIPDKVKKKYF------SGQGKL 252
                +K  R  L+RSPSMP ++ RP LK++E+ +D   P + K++          + + 
Sbjct: 272 -----SKCQR--LFRSPSMPCSVIRPILKRLERPQDRDTPVQNKRRRSVTPPEEQQEAEE 324

Query: 253 RKGLCLKKTVSLCDITITQMLEEDSNQGHLIGDFSKVCALPTVSGKHQDLKYVNPETVAA 312
            K   L+   SLC   I  +L+ D  +  LIGD+SK   L TV GKHQDLKY++PET+ A
Sbjct: 325 PKARVLRSK-SLCHDEIENLLDSDHRE--LIGDYSKAFLLQTVDGKHQDLKYISPETMVA 381

Query: 313 LLSGKFQGLIEKFYVIDCRYPYEYLGGHIQGALNLYSQEELFNFFLKKPIVPLDTQKRII 372
           LL+GKF  +++KF ++DCRYPYEY GGHI+ A+NL  + +  +F LK PI P    KR+I
Sbjct: 382 LLTGKFSNIVDKFVIVDCRYPYEYEGGHIKTAVNLPLERDAESFLLKSPIAPCSLDKRVI 441

Query: 373 IVFHCEFSSERGPRMCRCLREEDRSLNQYPALYYPELYILKGGYRDFFPEYMELCEPQSY 432
           ++FHCEFSSERGPRMCR +RE DR++N YP+LYYPE+YILKGGY++FFP++   CEPQ Y
Sbjct: 442 LIFHCEFSSERGPRMCRFIRERDRAVNDYPSLYYPEMYILKGGYKEFFPQHPNFCEPQDY 501

Query: 433 CPMHHQDHKTELLRCRSQSKVQEGERQLRE 462
            PM+H+  K EL   R +++   GER  RE
Sbjct: 502 RPMNHEAFKDELKTFRLKTRSWAGERSRRE 531


>gi|4757950 cell division cycle 25B isoform 2 [Homo sapiens]
          Length = 566

 Score =  265 bits (676), Expect = 9e-71
 Identities = 143/330 (43%), Positives = 208/330 (63%), Gaps = 20/330 (6%)

Query: 141 RDAMCSSSANKENDNG--NLVDSEMKYLGSPITTVPKLDKNPNLGEDQAEEISDELMEFS 198
           R ++  +  + E D+G  ++++S++K   +    +  L   P +   + EE  D +M   
Sbjct: 241 RFSLTPAEGDTEEDDGFVDILESDLKDDDAVPPGMESLISAPLVKTLEKEEEKDLVMY-- 298

Query: 199 LKDQEAKVSRSGLYRSPSMPENLNRPRLKQVEKFKDNTIPDKVKKKYF------SGQGKL 252
                +K  R  L+RSPSMP ++ RP LK++E+ +D   P + K++          + + 
Sbjct: 299 -----SKCQR--LFRSPSMPCSVIRPILKRLERPQDRDTPVQNKRRRSVTPPEEQQEAEE 351

Query: 253 RKGLCLKKTVSLCDITITQMLEEDSNQGHLIGDFSKVCALPTVSGKHQDLKYVNPETVAA 312
            K   L+   SLC   I  +L+ D  +  LIGD+SK   L TV GKHQDLKY++PET+ A
Sbjct: 352 PKARVLRSK-SLCHDEIENLLDSDHRE--LIGDYSKAFLLQTVDGKHQDLKYISPETMVA 408

Query: 313 LLSGKFQGLIEKFYVIDCRYPYEYLGGHIQGALNLYSQEELFNFFLKKPIVPLDTQKRII 372
           LL+GKF  +++KF ++DCRYPYEY GGHI+ A+NL  + +  +F LK PI P    KR+I
Sbjct: 409 LLTGKFSNIVDKFVIVDCRYPYEYEGGHIKTAVNLPLERDAESFLLKSPIAPCSLDKRVI 468

Query: 373 IVFHCEFSSERGPRMCRCLREEDRSLNQYPALYYPELYILKGGYRDFFPEYMELCEPQSY 432
           ++FHCEFSSERGPRMCR +RE DR++N YP+LYYPE+YILKGGY++FFP++   CEPQ Y
Sbjct: 469 LIFHCEFSSERGPRMCRFIRERDRAVNDYPSLYYPEMYILKGGYKEFFPQHPNFCEPQDY 528

Query: 433 CPMHHQDHKTELLRCRSQSKVQEGERQLRE 462
            PM+H+  K EL   R +++   GER  RE
Sbjct: 529 RPMNHEAFKDELKTFRLKTRSWAGERSRRE 558


>gi|42490760 cell division cycle 25A isoform b [Homo sapiens]
          Length = 484

 Score =  262 bits (669), Expect = 6e-70
 Identities = 172/437 (39%), Positives = 246/437 (56%), Gaps = 41/437 (9%)

Query: 65  GGTPKRCLDLSNLSSGEITATQLTTSAD--LDETGHLDSSGLQEVHLAGMNH-DQHLMKC 121
           G   ++ L++ N S+ +   +  +T +   LD  G LDS    E  +  ++   Q L+ C
Sbjct: 56  GSDYEQPLEVKNNSNLQRMGSSESTDSGFCLDSPGPLDSKENLENPMRRIHSLPQKLLGC 115

Query: 122 SPAQLLCSTPNGLDRGHRKRDAMCSSSANKENDNGNLVDSEMKYLGSPITTVPKLDKNPN 181
           SPA L  S  + LD    +   +     NKEN + N  DS       P+ T P+      
Sbjct: 116 SPA-LKRSHSDSLDHDIFQ---LIDPDENKENLSSNERDSSEPGNFIPLFT-PQSPVTAT 170

Query: 182 LGEDQAEEISDELMEFSLKDQEAKVS-------------------RSGLYRSPSMPENLN 222
           L  D+ +   D L   +LK++E   S                   R  L+ SPS+  +  
Sbjct: 171 LS-DEDDGFVDLLDGENLKNEEETPSCMASLWTAPLVMRTTNLDNRCKLFDSPSLCSSST 229

Query: 223 RPRLKQVEKFKDNTIPDKVKKKYFSGQGKLRKGL-------CLKKTVSLCDI---TITQM 272
           R  LK+ E+ ++ + P   K++        ++          L +++SL      TI  +
Sbjct: 230 RSVLKRPERSQEESPPGSTKRRKSMSGASPKESTNPEKAHETLHQSLSLASSPKGTIENI 289

Query: 273 LEEDSNQGHLIGDFSKVCALPTVSGKHQDLKYVNPETVAALLSGKFQGLIEKFYVIDCRY 332
           L+ D     LIGDFSK     TV+GKHQDLKY++PE +A++L+GKF  LI++F +IDCRY
Sbjct: 290 LDNDPRD--LIGDFSKGYLFHTVAGKHQDLKYISPEIMASVLNGKFANLIKEFVIIDCRY 347

Query: 333 PYEYLGGHIQGALNLYSQEELFNFFLKKPIVPLDTQKRIIIVFHCEFSSERGPRMCRCLR 392
           PYEY GGHI+GA+NL+ +EE+ +F LKKPIVP D  KR+I+VFHCEFSSERGPRMCR +R
Sbjct: 348 PYEYEGGHIKGAVNLHMEEEVEDFLLKKPIVPTDG-KRVIVVFHCEFSSERGPRMCRYVR 406

Query: 393 EEDRSLNQYPALYYPELYILKGGYRDFFPEYMELCEPQSYCPMHHQDHKTELLRCRSQSK 452
           E DR  N+YP L+YPELY+LKGGY++FF +    CEP SY PMHH+D K +L + R++S+
Sbjct: 407 ERDRLGNEYPKLHYPELYVLKGGYKEFFMKCQSYCEPPSYRPMHHEDFKEDLKKFRTKSR 466

Query: 453 VQEGERQLREQIALLVK 469
              GE+  RE  + L K
Sbjct: 467 TWAGEKSKREMYSRLKK 483


>gi|42490758 cell division cycle 25A isoform a [Homo sapiens]
          Length = 524

 Score =  255 bits (652), Expect = 5e-68
 Identities = 132/273 (48%), Positives = 183/273 (67%), Gaps = 13/273 (4%)

Query: 207 SRSGLYRSPSMPENLNRPRLKQVEKFKDNTIPDKVKKKYFSGQGKLRKGL-------CLK 259
           +R  L+ SPS+  +  R  LK+ E+ ++ + P   K++        ++          L 
Sbjct: 254 NRCKLFDSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGASPKESTNPEKAHETLH 313

Query: 260 KTVSLCDI---TITQMLEEDSNQGHLIGDFSKVCALPTVSGKHQDLKYVNPETVAALLSG 316
           +++SL      TI  +L+ D     LIGDFSK     TV+GKHQDLKY++PE +A++L+G
Sbjct: 314 QSLSLASSPKGTIENILDNDPRD--LIGDFSKGYLFHTVAGKHQDLKYISPEIMASVLNG 371

Query: 317 KFQGLIEKFYVIDCRYPYEYLGGHIQGALNLYSQEELFNFFLKKPIVPLDTQKRIIIVFH 376
           KF  LI++F +IDCRYPYEY GGHI+GA+NL+ +EE+ +F LKKPIVP D  KR+I+VFH
Sbjct: 372 KFANLIKEFVIIDCRYPYEYEGGHIKGAVNLHMEEEVEDFLLKKPIVPTDG-KRVIVVFH 430

Query: 377 CEFSSERGPRMCRCLREEDRSLNQYPALYYPELYILKGGYRDFFPEYMELCEPQSYCPMH 436
           CEFSSERGPRMCR +RE DR  N+YP L+YPELY+LKGGY++FF +    CEP SY PMH
Sbjct: 431 CEFSSERGPRMCRYVRERDRLGNEYPKLHYPELYVLKGGYKEFFMKCQSYCEPPSYRPMH 490

Query: 437 HQDHKTELLRCRSQSKVQEGERQLREQIALLVK 469
           H+D K +L + R++S+   GE+  RE  + L K
Sbjct: 491 HEDFKEDLKKFRTKSRTWAGEKSKREMYSRLKK 523


>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
          Length = 2803

 Score = 35.8 bits (81), Expect = 0.087
 Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 1/87 (1%)

Query: 160 DSEMKYLGSPITTVPKLDKNPNLGEDQAEEISDELM-EFSLKDQEAKVSRSGLYRSPSMP 218
           DS+     +  T V KL K   + E+ A+E   EL  E +  +++AK S       P+ P
Sbjct: 318 DSKESLKATTKTAVSKLAKREEVVEEGAKEARSELAKELAKTEKKAKESSEKPPEKPAKP 377

Query: 219 ENLNRPRLKQVEKFKDNTIPDKVKKKY 245
           E +     + ++  K   I DKV KK+
Sbjct: 378 ERVKTESSEALKAEKRKLIKDKVGKKH 404


>gi|7019493 DNA-directed DNA polymerase mu [Homo sapiens]
          Length = 494

 Score = 34.3 bits (77), Expect = 0.25
 Identities = 22/74 (29%), Positives = 39/74 (52%), Gaps = 6/74 (8%)

Query: 146 SSSANKENDNGNLVD-----SEMKYLGSPITTVPKLDKNPNLGEDQAEEISDELMEFSLK 200
           + +A  E   G L+      S +K L SP+TT+ +L   P+ GE  +  +  EL+E  + 
Sbjct: 164 AEAAGFEGSEGRLLTFCRAASVLKALPSPVTTLSQLQGLPHFGE-HSSRVVQELLEHGVC 222

Query: 201 DQEAKVSRSGLYRS 214
           ++  +V RS  Y++
Sbjct: 223 EEVERVRRSERYQT 236


>gi|62865890 dual specificity phosphatase 5 [Homo sapiens]
          Length = 384

 Score = 33.9 bits (76), Expect = 0.33
 Identities = 19/51 (37%), Positives = 26/51 (50%), Gaps = 5/51 (9%)

Query: 382 ERGPRMCRCLREEDRSLNQYPALYY-----PELYILKGGYRDFFPEYMELC 427
           ++G R  + LREE  +     +L       P +Y LKGGY  F+ EY E C
Sbjct: 90  DQGSRHWQKLREESAARVVLTSLLACLPAGPRVYFLKGGYETFYSEYPECC 140


>gi|34328899 protein tyrosine phosphatase, non-receptor type 14
           [Homo sapiens]
          Length = 1187

 Score = 33.1 bits (74), Expect = 0.56
 Identities = 13/46 (28%), Positives = 29/46 (63%)

Query: 192 DELMEFSLKDQEAKVSRSGLYRSPSMPENLNRPRLKQVEKFKDNTI 237
           +E M F+  +Q  K   +G++ + ++PEN  R R+++V  +++N +
Sbjct: 905 EEGMVFTEYEQIPKKKANGIFSTAALPENAERSRIREVVPYEENRV 950


>gi|148806928 hypothetical protein LOC57482 [Homo sapiens]
          Length = 1233

 Score = 32.7 bits (73), Expect = 0.73
 Identities = 24/63 (38%), Positives = 39/63 (61%), Gaps = 8/63 (12%)

Query: 186  QAEEISDELMEFSLKDQEAKVSRSG-LYRSPSMPENLNRP-----RLKQVEKFKD-NTIP 238
            QAE++S E +  S++   + VSR+G L++S ++PE   RP     RL++ E+ K  NT+P
Sbjct: 1118 QAEKLSKENVSVSVQPGSSSVSRAGSLHKSTALPEE-KRPETAVSRLERREQLKKANTLP 1176

Query: 239  DKV 241
              V
Sbjct: 1177 TSV 1179


>gi|54792136 follistatin-like 4 [Homo sapiens]
          Length = 842

 Score = 32.3 bits (72), Expect = 0.96
 Identities = 18/50 (36%), Positives = 23/50 (46%)

Query: 78  SSGEITATQLTTSADLDETGHLDSSGLQEVHLAGMNHDQHLMKCSPAQLL 127
           S   +    L    D D  GHL SS L +  L   + D+ L+ CSP  LL
Sbjct: 173 SQKRLLVESLFRDLDADGNGHLSSSELAQHVLKKQDLDEDLLGCSPGDLL 222


>gi|217035118 TBC1 domain family, member 23 [Homo sapiens]
          Length = 684

 Score = 31.6 bits (70), Expect = 1.6
 Identities = 16/43 (37%), Positives = 24/43 (55%)

Query: 313 LLSGKFQGLIEKFYVIDCRYPYEYLGGHIQGALNLYSQEELFN 355
           L + + QG   +F+V+DCR   +Y  GH+  A +L S   L N
Sbjct: 326 LQANQLQGEGVRFFVVDCRPAEQYNAGHLSTAFHLDSDLMLQN 368


>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
            transmembrane signal), 1 [Homo sapiens]
          Length = 3259

 Score = 30.8 bits (68), Expect = 2.8
 Identities = 47/247 (19%), Positives = 100/247 (40%), Gaps = 35/247 (14%)

Query: 143  AMCSSSANKENDNGNLVDSEMKYLGSPITTVPKLDKNPNLGEDQAEEISDELMEFSLKDQ 202
            A   S ++ ++D   ++D   K+       +   ++   L ED    + D+L + S+  +
Sbjct: 2189 AFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHME 2248

Query: 203  EAKVSRSGLYRSPSMPENLNRPRLKQVEKFKDN---------TIPDKVKKKYFSGQGKLR 253
            E K++ S L     + E+  +  ++  +K  D          +  ++ +  Y S Q +L 
Sbjct: 2249 ELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELA 2308

Query: 254  KGLCLKKTVSLCDITITQMLEEDSNQ-GHLIG-------------------DFSKVCALP 293
            K     K++      ++  LE+   Q G+L G                   +     +  
Sbjct: 2309 KLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRE 2368

Query: 294  TVSGKHQDLKYVNPETVAALLSGKFQGLIEKFYVIDCRYPYEYLGGHIQGALNLYSQEEL 353
              S  H+++  +  + + +LLSGK + +  +  + + R  ++     I+   NL SQEE 
Sbjct: 2369 LTSRLHEEIN-MKEQKIISLLSGKEEAI--QVAIAELRQQHD---KEIKELENLLSQEEE 2422

Query: 354  FNFFLKK 360
             N  L++
Sbjct: 2423 ENIVLEE 2429


>gi|154146191 heat shock 90kDa protein 1, alpha isoform 2 [Homo
           sapiens]
          Length = 732

 Score = 30.4 bits (67), Expect = 3.6
 Identities = 26/104 (25%), Positives = 49/104 (47%), Gaps = 24/104 (23%)

Query: 158 LVDSEMKYLGSPITTVPKLDKNPNLGEDQAEEISDELMEFSLKDQEAKVSRSGLYRSPSM 217
           +V    +++G PIT   + +++  + +D+AEE  D+  E   K++E K            
Sbjct: 206 IVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEE---KEKEEK------------ 250

Query: 218 PENLNRPRLKQV-------EKFKDNTIPDKVKKKYFSGQGKLRK 254
            E+ ++P ++ V       +K  D     K+K+KY   Q +L K
Sbjct: 251 -ESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYID-QEELNK 292


>gi|153792590 heat shock 90kDa protein 1, alpha isoform 1 [Homo
           sapiens]
          Length = 854

 Score = 30.4 bits (67), Expect = 3.6
 Identities = 26/104 (25%), Positives = 49/104 (47%), Gaps = 24/104 (23%)

Query: 158 LVDSEMKYLGSPITTVPKLDKNPNLGEDQAEEISDELMEFSLKDQEAKVSRSGLYRSPSM 217
           +V    +++G PIT   + +++  + +D+AEE  D+  E   K++E K            
Sbjct: 328 IVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEE---KEKEEK------------ 372

Query: 218 PENLNRPRLKQV-------EKFKDNTIPDKVKKKYFSGQGKLRK 254
            E+ ++P ++ V       +K  D     K+K+KY   Q +L K
Sbjct: 373 -ESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYID-QEELNK 414


>gi|20149594 heat shock 90kDa protein 1, beta [Homo sapiens]
          Length = 724

 Score = 30.4 bits (67), Expect = 3.6
 Identities = 21/86 (24%), Positives = 38/86 (44%), Gaps = 1/86 (1%)

Query: 158 LVDSEMKYLGSPITTVPKLDKNPNLGEDQAEEISDELMEFSLKDQE-AKVSRSGLYRSPS 216
           +V    +++G PIT   + ++   + +D+AEE   E  E    D+E  K+   G      
Sbjct: 201 VVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDD 260

Query: 217 MPENLNRPRLKQVEKFKDNTIPDKVK 242
             ++  +   K  EK+ D    +K K
Sbjct: 261 SGKDKKKKTKKIKEKYIDQEELNKTK 286


>gi|90652857 hypothetical protein LOC84904 [Homo sapiens]
          Length = 335

 Score = 30.4 bits (67), Expect = 3.6
 Identities = 16/44 (36%), Positives = 25/44 (56%)

Query: 424 MELCEPQSYCPMHHQDHKTELLRCRSQSKVQEGERQLREQIALL 467
           MEL  P S CP+  Q  + E  R  +  ++ E ER+ +EQ+ L+
Sbjct: 1   MELSCPGSRCPVQEQRARWERKRACTARELLETERRYQEQLGLV 44


>gi|4885579 RCD1 required for cell differentiation1 homolog [Homo
           sapiens]
          Length = 299

 Score = 29.6 bits (65), Expect = 6.2
 Identities = 20/64 (31%), Positives = 32/64 (50%), Gaps = 4/64 (6%)

Query: 306 NPETVAALLSGKFQGLIEKF-YVIDCRYPYEYL---GGHIQGALNLYSQEELFNFFLKKP 361
           +PET +A L+      +  F + +    P+EYL      + GAL    ++E+ NF L   
Sbjct: 103 HPETRSAFLAAHIPLFLYPFLHTVSKTRPFEYLRLTSLGVIGALVKTDEQEVINFLLTTE 162

Query: 362 IVPL 365
           I+PL
Sbjct: 163 IIPL 166


>gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens]
          Length = 394

 Score = 29.6 bits (65), Expect = 6.2
 Identities = 32/121 (26%), Positives = 50/121 (41%), Gaps = 23/121 (19%)

Query: 324 KFYVIDCRYPYEYLGGHIQGALNLYS----QEELFNFFLKKPIVPLDTQKRI-------- 371
           K  ++DCR    +  G+I G++N+      +         + I+P + + R         
Sbjct: 44  KCLLLDCRPFLAHSAGYILGSVNVRCNTIVRRRAKGSVSLEQILPAEEEVRARLRSGLYS 103

Query: 372 -IIVFHCEFSSERGPRMCRCLREEDRSLNQYPALYY----PELYILKGGYRDFFPEYMEL 426
            +IV+      ER PR    LRE+        AL       ++ +LKGGY  F  EY E 
Sbjct: 104 AVIVY-----DERSPR-AESLREDSTVSLVVQALRRNAERTDICLLKGGYERFSSEYPEF 157

Query: 427 C 427
           C
Sbjct: 158 C 158


>gi|22095388 islet cell autoantigen 1,69kDa-like isoform 1 [Homo
           sapiens]
          Length = 482

 Score = 29.6 bits (65), Expect = 6.2
 Identities = 28/105 (26%), Positives = 45/105 (42%), Gaps = 7/105 (6%)

Query: 190 ISDELMEFSLKDQEAKVSRSGLYRSPSMPENLNRPRLKQVEKFKDNTIPDKVKKKYFSGQ 249
           +SD LM  +  +Q     R  L     + + L+   LKQ+EKF+   +  +  K  F   
Sbjct: 142 VSDTLMTINRMEQARTEYRGALLWMKDVSQELDPDTLKQMEKFRKVQMQVRNSKASFD-- 199

Query: 250 GKLRKGLCLKKTVSLCDITITQMLEED--SNQGHLIGDFSKVCAL 292
            KL+  +C K  V L   +   ML     + Q  L+G + K   +
Sbjct: 200 -KLKMDVCQK--VDLLGASRCNMLSHSLTTYQRTLLGFWKKTARM 241


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 29.3 bits (64), Expect = 8.1
 Identities = 25/101 (24%), Positives = 40/101 (39%), Gaps = 4/101 (3%)

Query: 146 SSSANKENDNGNLVDSEMKYLGSPITTVPKLDKNPNLGEDQAEEI-SDELMEFSLKDQEA 204
           SS+++  +D+    + ++K  GSP    PK +    L     +   + E  E   K    
Sbjct: 516 SSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAV 575

Query: 205 KVSRSGLYRSPSMPENLNRPRLKQVEKFK---DNTIPDKVK 242
            VS+SG  +     E        Q +K K    NT P + K
Sbjct: 576 VVSKSGSLKKRKQNEAAKEAETPQAKKIKLQTPNTFPKRKK 616


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.134    0.394 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,302,973
Number of Sequences: 37866
Number of extensions: 930257
Number of successful extensions: 2243
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 2218
Number of HSP's gapped (non-prelim): 27
length of query: 473
length of database: 18,247,518
effective HSP length: 106
effective length of query: 367
effective length of database: 14,233,722
effective search space: 5223775974
effective search space used: 5223775974
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.