Guide to the Human Genome
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Search of human proteins with 38348322

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|38348322 family with sequence similarity 174, member A [Homo
sapiens]
         (190 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|38348322 family with sequence similarity 174, member A [Homo ...   388   e-108
gi|150170694 hypothetical protein LOC400451 [Homo sapiens]             70   1e-12
gi|13994190 frizzled 8 [Homo sapiens]                                  43   2e-04
gi|82546824 forkhead box K1 [Homo sapiens]                             41   7e-04
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]         40   0.001
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...    40   0.001
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...    40   0.001
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...    40   0.001
gi|23510368 homeobox D11 [Homo sapiens]                                40   0.001
gi|39812378 RAN binding protein 9 [Homo sapiens]                       40   0.001
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap...    40   0.001
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      40   0.002
gi|54873613 agrin [Homo sapiens]                                       40   0.002
gi|50428940 mediator complex subunit 25 [Homo sapiens]                 40   0.002
gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]        40   0.002
gi|154816198 transcription elongation factor B polypeptide 3C-li...    40   0.002
gi|156938279 transcription elongation factor B polypeptide 3C [H...    40   0.002
gi|51479192 ring finger protein 1 [Homo sapiens]                       39   0.002
gi|189339239 hypothetical protein LOC55009 [Homo sapiens]              39   0.002
gi|122937424 one cut homeobox 3 [Homo sapiens]                         39   0.002
gi|116008152 alpha 1 type XV collagen precursor [Homo sapiens]         39   0.003
gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]          39   0.003
gi|31542493 D site of albumin promoter (albumin D-box) binding p...    39   0.003
gi|222136583 inositol polyphosphate phosphatase-like 1 [Homo sap...    39   0.004
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    39   0.004
gi|31657109 zinc finger protein 282 [Homo sapiens]                     39   0.004
gi|23510333 pygopus homolog 2 [Homo sapiens]                           39   0.004
gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribo...    38   0.005
gi|170016069 zinc finger, CCHC domain containing 2 [Homo sapiens]      38   0.005
gi|118498339 EMI domain containing 2 [Homo sapiens]                    38   0.005

>gi|38348322 family with sequence similarity 174, member A [Homo
           sapiens]
          Length = 190

 Score =  388 bits (997), Expect = e-108
 Identities = 190/190 (100%), Positives = 190/190 (100%)

Query: 1   MKASQCCCCLSHLLASVLLLLLLPELSGPLAVLLQAAEAAPGLGPPDPRPRTLPPLPPGP 60
           MKASQCCCCLSHLLASVLLLLLLPELSGPLAVLLQAAEAAPGLGPPDPRPRTLPPLPPGP
Sbjct: 1   MKASQCCCCLSHLLASVLLLLLLPELSGPLAVLLQAAEAAPGLGPPDPRPRTLPPLPPGP 60

Query: 61  TPAQQPGRGLAEAAGPRGSEGGNGSNPVAGLETDDHGGKAGEGSVGGGLAVSPNPGDKPM 120
           TPAQQPGRGLAEAAGPRGSEGGNGSNPVAGLETDDHGGKAGEGSVGGGLAVSPNPGDKPM
Sbjct: 61  TPAQQPGRGLAEAAGPRGSEGGNGSNPVAGLETDDHGGKAGEGSVGGGLAVSPNPGDKPM 120

Query: 121 TQRALTVLMVVSGAVLVYFVVRTVRMRRRNRKTRRYGVLDTNIENMELTPLEQDDEDDDN 180
           TQRALTVLMVVSGAVLVYFVVRTVRMRRRNRKTRRYGVLDTNIENMELTPLEQDDEDDDN
Sbjct: 121 TQRALTVLMVVSGAVLVYFVVRTVRMRRRNRKTRRYGVLDTNIENMELTPLEQDDEDDDN 180

Query: 181 TLFDANHPRR 190
           TLFDANHPRR
Sbjct: 181 TLFDANHPRR 190


>gi|150170694 hypothetical protein LOC400451 [Homo sapiens]
          Length = 159

 Score = 70.1 bits (170), Expect = 1e-12
 Identities = 56/176 (31%), Positives = 81/176 (46%), Gaps = 24/176 (13%)

Query: 13  LLASVLLLLLLPELSGPLAVLLQAAEAAPGLGPPDPRPRTLPPLPPGPTPAQQPGRGLAE 72
           L A +L LLLL  L+ P A     A  A  +  P P P      PPGP P      G + 
Sbjct: 6   LPAPLLPLLLLALLAAPAA----RASRAESVSAPWPEPERESRPPPGPGPGNTTRFG-SG 60

Query: 73  AAGPRGSEGGNGSNPVAGLETDDHGGKAGEGSVGGGLAVSPNPGDKPMTQRALTVLMVVS 132
           AAG  GS   N S               G+  V     +S    D P  + A+ V    +
Sbjct: 61  AAGGSGSSSSNSS---------------GDALV---TRISILLRDLPTLKAAVIVAFAFT 102

Query: 133 GAVLVYFVVRTVRMRRRNRKTRRYGVLDTNIENMELTPL-EQDDEDDDNTLFDANH 187
             ++   ++R  R  +R +KTR+Y ++ T  E +E+ PL E+DDED+D+T+FD  +
Sbjct: 103 TLLIACLLLRVFRSGKRLKKTRKYDIITTPAERVEMAPLNEEDDEDEDSTVFDIKY 158


>gi|13994190 frizzled 8 [Homo sapiens]
          Length = 694

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 31/97 (31%), Positives = 33/97 (34%), Gaps = 7/97 (7%)

Query: 23  LPELSGPLAVLLQAAEAAPGLGPPDPRPRTLPPLPPGPTPAQQPGRGLAEAAGPRGSEGG 82
           LPE   P  + +           P P PR LPP PPG  P    G G    A P    GG
Sbjct: 138 LPEQGNPDTLCMDYNRTDLTTAAPSP-PRRLPPPPPGEQPPSGSGHGRPPGARPPHRGGG 196

Query: 83  NGSNPVAGLETDDHGGKAGEGSVGGGLAVSPNPGDKP 119
            G          D       G  GGG A  P  G  P
Sbjct: 197 RGGG------GGDAAAPPARGGGGGGKARPPGGGAAP 227


>gi|82546824 forkhead box K1 [Homo sapiens]
          Length = 733

 Score = 40.8 bits (94), Expect = 7e-04
 Identities = 27/73 (36%), Positives = 31/73 (42%), Gaps = 1/73 (1%)

Query: 19 LLLLLPELSGPLAVLLQAAEAAPGLGPPD-PRPRTLPPLPPGPTPAQQPGRGLAEAAGPR 77
          LL L      P+     AA A P   PP  P     PP PP P P   P   +A A    
Sbjct: 13 LLALRSAPCSPVLCAAAAAAAFPAAAPPPAPAQPQPPPGPPPPPPPPLPPGAIAGAGSSG 72

Query: 78 GSEGGNGSNPVAG 90
          GS G +G + VAG
Sbjct: 73 GSSGVSGDSAVAG 85


>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
          Length = 1003

 Score = 40.4 bits (93), Expect = 0.001
 Identities = 46/129 (35%), Positives = 54/129 (41%), Gaps = 30/129 (23%)

Query: 13  LLASVLLLLLLP---------ELSGPLAVLLQAAEAAPGLGPPDPRPRTLPPLPPG---- 59
           LL+  L L LLP         E S PLA LLQ+ +    + P  P    LPP  P     
Sbjct: 768 LLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQ----IPPEQPEAPCLPPESPASALE 823

Query: 60  PTPAQQPGRGLAEAAGPRGSEGGNGSNPVAGLETDDHGGKAGEGSVGGGL-----AVSPN 114
           P PA+ P   L+  A P GS       PV  L T    GK G    GGGL        P 
Sbjct: 824 PEPARPP---LSALAPPHGSP----DPPVPELLTGRGSGKRGRRG-GGGLRGINGEARPA 875

Query: 115 PGDKPMTQR 123
            G KP ++R
Sbjct: 876 RGRKPGSRR 884


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
           sapiens]
          Length = 1818

 Score = 40.0 bits (92), Expect = 0.001
 Identities = 39/111 (35%), Positives = 46/111 (41%), Gaps = 20/111 (18%)

Query: 23  LPELSGPLAVL----LQAAEAAPGL----GPPDPRPRTLPPLPPGPTPAQQ--PG----R 68
           LP  +GP  +L       A   PG+    GPP P+    P   PGP P QQ  PG     
Sbjct: 656 LPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGP-PGQQGNPGPQGLP 714

Query: 69  GLAEAAGPRGSEGGNGSNPVAGLETDD----HGGKAGEGSVGGGLAVSPNP 115
           G     GP G +G  G   +AGL   D    H GK G+    G L   P P
Sbjct: 715 GPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALG-PPGP 764



 Score = 35.4 bits (80), Expect = 0.030
 Identities = 28/73 (38%), Positives = 30/73 (41%), Gaps = 12/73 (16%)

Query: 44   GPPDPRPRTLPPLPPGPTPAQQPGRGLAEAAGPRGSEGGNGSNPVAGLETDDHGGKAGEG 103
            GPP P     PP PPG        RG   AAG  G +G  G+   AG E    G     G
Sbjct: 1357 GPPGPSGEAGPPGPPGK-------RGPPGAAGAEGRQGEKGAKGEAGAE----GPPGKTG 1405

Query: 104  SVG-GGLAVSPNP 115
             VG  G A  P P
Sbjct: 1406 PVGPQGPAGKPGP 1418



 Score = 31.2 bits (69), Expect = 0.56
 Identities = 21/54 (38%), Positives = 27/54 (50%), Gaps = 10/54 (18%)

Query: 43   LGPPDPRPRTLP------PLPPGPTPAQQPGRGLAEAAGPRGSEGGNGSNPVAG 90
            +GP  P   T P      P PPGP P +Q   GL  AAG  G++G  G   ++G
Sbjct: 981  VGPQGPTGETGPIGERGHPGPPGP-PGEQ---GLPGAAGKEGAKGDPGPQGISG 1030



 Score = 30.8 bits (68), Expect = 0.73
 Identities = 30/90 (33%), Positives = 36/90 (40%), Gaps = 25/90 (27%)

Query: 38   EAAPGL-GPPDPRPRTLPPLPPGPT-------PAQQPGRGLAEAAGPRGSEGGNGSNPVA 89
            E A G  GPP P      P PPG         P   PG       GPRG +G NG++   
Sbjct: 1197 EGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPG-----PPGPRGPQGPNGAD--- 1248

Query: 90   GLETDDHGGKAGEGSVG--GGLAVSPNPGD 117
                   G +   GSVG  GG+     PG+
Sbjct: 1249 -------GPQGPPGSVGSVGGVGEKGEPGE 1271



 Score = 30.0 bits (66), Expect = 1.3
 Identities = 26/82 (31%), Positives = 32/82 (39%), Gaps = 7/82 (8%)

Query: 41  PGL----GPPDPRPRTLPPLPPGPTPAQQPGRGLAEAAGPRGSEGGNGSNPVAGLETDDH 96
           PGL    G   P+  T  P  PG    ++  RG+A   GPRG  G  G     G      
Sbjct: 852 PGLPGYPGRQGPKGSTGFPGFPGAN-GEKGARGVAGKPGPRGQRGPTGPRGSRGARGPT- 909

Query: 97  GGKAGEGSVGGGLAVSPNPGDK 118
            GK G     GG      PG++
Sbjct: 910 -GKPGPKGTSGGDGPPGPPGER 930



 Score = 28.5 bits (62), Expect = 3.6
 Identities = 35/113 (30%), Positives = 39/113 (34%), Gaps = 26/113 (23%)

Query: 25   ELSGPLAVLLQAAEAAPGLGPP--DPRPRTLP--PLPPG-PTPAQQPG------------ 67
            E   P A     A+  PG   P  +P P   P  P PPG P PA Q G            
Sbjct: 1295 EAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPG 1354

Query: 68   ----RGLAEAAGPRGSEGGNGSNPVAGLETDDHGGKAGEGSVGGGLAVSPNPG 116
                 G +  AGP G  G  G    AG E     G+ GE    G       PG
Sbjct: 1355 QPGPPGPSGEAGPPGPPGKRGPPGAAGAE-----GRQGEKGAKGEAGAEGPPG 1402



 Score = 28.1 bits (61), Expect = 4.8
 Identities = 33/96 (34%), Positives = 37/96 (38%), Gaps = 12/96 (12%)

Query: 23   LPELSGPLAVLLQAAE-AAPG-LGPPDPRPRTLPPLP---PGPT-PAQQPG----RGLAE 72
            LP   GP      A E  APG  GP  P  R     P   PGP  PA  PG    +G   
Sbjct: 1085 LPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIG 1144

Query: 73   AAGPRGSEGGNGSNPVAGLETDDHGGKAGEGSVGGG 108
              G +GS+G  G N   G       G  G   + GG
Sbjct: 1145 EPGQKGSKGDKGENGPPG--PPGLQGPVGAPGIAGG 1178



 Score = 27.3 bits (59), Expect = 8.1
 Identities = 18/49 (36%), Positives = 21/49 (42%), Gaps = 2/49 (4%)

Query: 68  RGLAEAAGPRGSEGGNGSNPVAGLETDDHGGKAGEGSVGGGLAVSPNPG 116
           RG     GPRG +G  G    AG   D   G +G+    G L V   PG
Sbjct: 810 RGEVGQIGPRGEDGPEGPKGRAGPTGDP--GPSGQAGEKGKLGVPGLPG 856


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
           sapiens]
          Length = 1767

 Score = 40.0 bits (92), Expect = 0.001
 Identities = 39/111 (35%), Positives = 46/111 (41%), Gaps = 20/111 (18%)

Query: 23  LPELSGPLAVL----LQAAEAAPGL----GPPDPRPRTLPPLPPGPTPAQQ--PG----R 68
           LP  +GP  +L       A   PG+    GPP P+    P   PGP P QQ  PG     
Sbjct: 605 LPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGP-PGQQGNPGPQGLP 663

Query: 69  GLAEAAGPRGSEGGNGSNPVAGLETDD----HGGKAGEGSVGGGLAVSPNP 115
           G     GP G +G  G   +AGL   D    H GK G+    G L   P P
Sbjct: 664 GPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALG-PPGP 713



 Score = 35.4 bits (80), Expect = 0.030
 Identities = 28/73 (38%), Positives = 30/73 (41%), Gaps = 12/73 (16%)

Query: 44   GPPDPRPRTLPPLPPGPTPAQQPGRGLAEAAGPRGSEGGNGSNPVAGLETDDHGGKAGEG 103
            GPP P     PP PPG        RG   AAG  G +G  G+   AG E    G     G
Sbjct: 1306 GPPGPSGEAGPPGPPGK-------RGPPGAAGAEGRQGEKGAKGEAGAE----GPPGKTG 1354

Query: 104  SVG-GGLAVSPNP 115
             VG  G A  P P
Sbjct: 1355 PVGPQGPAGKPGP 1367



 Score = 31.2 bits (69), Expect = 0.56
 Identities = 21/54 (38%), Positives = 27/54 (50%), Gaps = 10/54 (18%)

Query: 43  LGPPDPRPRTLP------PLPPGPTPAQQPGRGLAEAAGPRGSEGGNGSNPVAG 90
           +GP  P   T P      P PPGP P +Q   GL  AAG  G++G  G   ++G
Sbjct: 930 VGPQGPTGETGPIGERGHPGPPGP-PGEQ---GLPGAAGKEGAKGDPGPQGISG 979



 Score = 30.8 bits (68), Expect = 0.73
 Identities = 30/90 (33%), Positives = 36/90 (40%), Gaps = 25/90 (27%)

Query: 38   EAAPGL-GPPDPRPRTLPPLPPGPT-------PAQQPGRGLAEAAGPRGSEGGNGSNPVA 89
            E A G  GPP P      P PPG         P   PG       GPRG +G NG++   
Sbjct: 1146 EGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPG-----PPGPRGPQGPNGAD--- 1197

Query: 90   GLETDDHGGKAGEGSVG--GGLAVSPNPGD 117
                   G +   GSVG  GG+     PG+
Sbjct: 1198 -------GPQGPPGSVGSVGGVGEKGEPGE 1220



 Score = 30.0 bits (66), Expect = 1.3
 Identities = 26/82 (31%), Positives = 32/82 (39%), Gaps = 7/82 (8%)

Query: 41  PGL----GPPDPRPRTLPPLPPGPTPAQQPGRGLAEAAGPRGSEGGNGSNPVAGLETDDH 96
           PGL    G   P+  T  P  PG    ++  RG+A   GPRG  G  G     G      
Sbjct: 801 PGLPGYPGRQGPKGSTGFPGFPGAN-GEKGARGVAGKPGPRGQRGPTGPRGSRGARGPT- 858

Query: 97  GGKAGEGSVGGGLAVSPNPGDK 118
            GK G     GG      PG++
Sbjct: 859 -GKPGPKGTSGGDGPPGPPGER 879



 Score = 28.5 bits (62), Expect = 3.6
 Identities = 35/113 (30%), Positives = 39/113 (34%), Gaps = 26/113 (23%)

Query: 25   ELSGPLAVLLQAAEAAPGLGPP--DPRPRTLP--PLPPG-PTPAQQPG------------ 67
            E   P A     A+  PG   P  +P P   P  P PPG P PA Q G            
Sbjct: 1244 EAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPG 1303

Query: 68   ----RGLAEAAGPRGSEGGNGSNPVAGLETDDHGGKAGEGSVGGGLAVSPNPG 116
                 G +  AGP G  G  G    AG E     G+ GE    G       PG
Sbjct: 1304 QPGPPGPSGEAGPPGPPGKRGPPGAAGAE-----GRQGEKGAKGEAGAEGPPG 1351



 Score = 28.1 bits (61), Expect = 4.8
 Identities = 33/96 (34%), Positives = 37/96 (38%), Gaps = 12/96 (12%)

Query: 23   LPELSGPLAVLLQAAE-AAPG-LGPPDPRPRTLPPLP---PGPT-PAQQPG----RGLAE 72
            LP   GP      A E  APG  GP  P  R     P   PGP  PA  PG    +G   
Sbjct: 1034 LPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIG 1093

Query: 73   AAGPRGSEGGNGSNPVAGLETDDHGGKAGEGSVGGG 108
              G +GS+G  G N   G       G  G   + GG
Sbjct: 1094 EPGQKGSKGDKGENGPPG--PPGLQGPVGAPGIAGG 1127



 Score = 27.3 bits (59), Expect = 8.1
 Identities = 18/49 (36%), Positives = 21/49 (42%), Gaps = 2/49 (4%)

Query: 68  RGLAEAAGPRGSEGGNGSNPVAGLETDDHGGKAGEGSVGGGLAVSPNPG 116
           RG     GPRG +G  G    AG   D   G +G+    G L V   PG
Sbjct: 759 RGEVGQIGPRGEDGPEGPKGRAGPTGDP--GPSGQAGEKGKLGVPGLPG 805


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
           sapiens]
          Length = 1806

 Score = 40.0 bits (92), Expect = 0.001
 Identities = 39/111 (35%), Positives = 46/111 (41%), Gaps = 20/111 (18%)

Query: 23  LPELSGPLAVL----LQAAEAAPGL----GPPDPRPRTLPPLPPGPTPAQQ--PG----R 68
           LP  +GP  +L       A   PG+    GPP P+    P   PGP P QQ  PG     
Sbjct: 644 LPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGP-PGQQGNPGPQGLP 702

Query: 69  GLAEAAGPRGSEGGNGSNPVAGLETDD----HGGKAGEGSVGGGLAVSPNP 115
           G     GP G +G  G   +AGL   D    H GK G+    G L   P P
Sbjct: 703 GPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALG-PPGP 752



 Score = 35.4 bits (80), Expect = 0.030
 Identities = 28/73 (38%), Positives = 30/73 (41%), Gaps = 12/73 (16%)

Query: 44   GPPDPRPRTLPPLPPGPTPAQQPGRGLAEAAGPRGSEGGNGSNPVAGLETDDHGGKAGEG 103
            GPP P     PP PPG        RG   AAG  G +G  G+   AG E    G     G
Sbjct: 1345 GPPGPSGEAGPPGPPGK-------RGPPGAAGAEGRQGEKGAKGEAGAE----GPPGKTG 1393

Query: 104  SVG-GGLAVSPNP 115
             VG  G A  P P
Sbjct: 1394 PVGPQGPAGKPGP 1406



 Score = 31.2 bits (69), Expect = 0.56
 Identities = 21/54 (38%), Positives = 27/54 (50%), Gaps = 10/54 (18%)

Query: 43   LGPPDPRPRTLP------PLPPGPTPAQQPGRGLAEAAGPRGSEGGNGSNPVAG 90
            +GP  P   T P      P PPGP P +Q   GL  AAG  G++G  G   ++G
Sbjct: 969  VGPQGPTGETGPIGERGHPGPPGP-PGEQ---GLPGAAGKEGAKGDPGPQGISG 1018



 Score = 30.8 bits (68), Expect = 0.73
 Identities = 30/90 (33%), Positives = 36/90 (40%), Gaps = 25/90 (27%)

Query: 38   EAAPGL-GPPDPRPRTLPPLPPGPT-------PAQQPGRGLAEAAGPRGSEGGNGSNPVA 89
            E A G  GPP P      P PPG         P   PG       GPRG +G NG++   
Sbjct: 1185 EGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPG-----PPGPRGPQGPNGAD--- 1236

Query: 90   GLETDDHGGKAGEGSVG--GGLAVSPNPGD 117
                   G +   GSVG  GG+     PG+
Sbjct: 1237 -------GPQGPPGSVGSVGGVGEKGEPGE 1259



 Score = 30.0 bits (66), Expect = 1.3
 Identities = 26/82 (31%), Positives = 32/82 (39%), Gaps = 7/82 (8%)

Query: 41  PGL----GPPDPRPRTLPPLPPGPTPAQQPGRGLAEAAGPRGSEGGNGSNPVAGLETDDH 96
           PGL    G   P+  T  P  PG    ++  RG+A   GPRG  G  G     G      
Sbjct: 840 PGLPGYPGRQGPKGSTGFPGFPGAN-GEKGARGVAGKPGPRGQRGPTGPRGSRGARGPT- 897

Query: 97  GGKAGEGSVGGGLAVSPNPGDK 118
            GK G     GG      PG++
Sbjct: 898 -GKPGPKGTSGGDGPPGPPGER 918



 Score = 28.5 bits (62), Expect = 3.6
 Identities = 35/113 (30%), Positives = 39/113 (34%), Gaps = 26/113 (23%)

Query: 25   ELSGPLAVLLQAAEAAPGLGPP--DPRPRTLP--PLPPG-PTPAQQPG------------ 67
            E   P A     A+  PG   P  +P P   P  P PPG P PA Q G            
Sbjct: 1283 EAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPG 1342

Query: 68   ----RGLAEAAGPRGSEGGNGSNPVAGLETDDHGGKAGEGSVGGGLAVSPNPG 116
                 G +  AGP G  G  G    AG E     G+ GE    G       PG
Sbjct: 1343 QPGPPGPSGEAGPPGPPGKRGPPGAAGAE-----GRQGEKGAKGEAGAEGPPG 1390



 Score = 28.1 bits (61), Expect = 4.8
 Identities = 33/96 (34%), Positives = 37/96 (38%), Gaps = 12/96 (12%)

Query: 23   LPELSGPLAVLLQAAE-AAPG-LGPPDPRPRTLPPLP---PGPT-PAQQPG----RGLAE 72
            LP   GP      A E  APG  GP  P  R     P   PGP  PA  PG    +G   
Sbjct: 1073 LPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIG 1132

Query: 73   AAGPRGSEGGNGSNPVAGLETDDHGGKAGEGSVGGG 108
              G +GS+G  G N   G       G  G   + GG
Sbjct: 1133 EPGQKGSKGDKGENGPPG--PPGLQGPVGAPGIAGG 1166



 Score = 27.3 bits (59), Expect = 8.1
 Identities = 18/49 (36%), Positives = 21/49 (42%), Gaps = 2/49 (4%)

Query: 68  RGLAEAAGPRGSEGGNGSNPVAGLETDDHGGKAGEGSVGGGLAVSPNPG 116
           RG     GPRG +G  G    AG   D   G +G+    G L V   PG
Sbjct: 798 RGEVGQIGPRGEDGPEGPKGRAGPTGDP--GPSGQAGEKGKLGVPGLPG 844


>gi|23510368 homeobox D11 [Homo sapiens]
          Length = 338

 Score = 40.0 bits (92), Expect = 0.001
 Identities = 30/74 (40%), Positives = 33/74 (44%), Gaps = 8/74 (10%)

Query: 35  QAAEAAPGLGPPDPRPRTLPPLPPGPTPAQQPGRGLAEAAGPRGSEGGNGSNPVAGLETD 94
           Q  EAAPG  PP   P+  PP PP P    QP  G A+   PR   GG G +P       
Sbjct: 180 QFYEAAPG--PPFAGPQ--PPPPPAPP---QP-EGAADKGDPRTGAGGGGGSPCTKATPG 231

Query: 95  DHGGKAGEGSVGGG 108
                A EGS G G
Sbjct: 232 SEPKGAAEGSGGDG 245


>gi|39812378 RAN binding protein 9 [Homo sapiens]
          Length = 729

 Score = 40.0 bits (92), Expect = 0.001
 Identities = 31/92 (33%), Positives = 36/92 (39%), Gaps = 10/92 (10%)

Query: 34  LQAAEAAPGLGPPDPRPRTLPPLPPGPTPAQQPGRGLAEAAGPRGSEG-GNGSNPVAGLE 92
           L AA AA  L PP P P      PP P P   P    A A+GP    G   G  P  G  
Sbjct: 60  LGAAAAALLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGPGPAGGAP 119

Query: 93  TDDHGGKAGEGSVGGGLAVSPNP-GDKPMTQR 123
           T           V G  A +P P GD  + ++
Sbjct: 120 T--------PALVAGSSAAAPFPHGDSALNEQ 143



 Score = 28.5 bits (62), Expect = 3.6
 Identities = 21/77 (27%), Positives = 28/77 (36%), Gaps = 5/77 (6%)

Query: 45  PPDPRPRTLPPLPPGPTPAQQPGRGLAEAAGPRGSEGGNGSNPVAGLETDDHGGKAGEGS 104
           PP  + +    L P P  A  P  G+   A P  S G + +    G       G  G G+
Sbjct: 8   PPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGG-----GAGGEGLGA 62

Query: 105 VGGGLAVSPNPGDKPMT 121
               L + P P   P T
Sbjct: 63  AAAALLLHPPPPPPPAT 79


>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
          Length = 2161

 Score = 40.0 bits (92), Expect = 0.001
 Identities = 29/99 (29%), Positives = 38/99 (38%), Gaps = 8/99 (8%)

Query: 23   LPELSGPLAVLLQAAEAAPGLGPPDPRPRTLPPLP----PGPTPAQQPGRGLAEAAGPRG 78
            L      +A L Q A AAPG   P   P    P P    PGP P      G+ E      
Sbjct: 1624 LTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPAPAAPQPGPDPPPGTDSGIEEVDSRSS 1683

Query: 79   S----EGGNGSNPVAGLETDDHGGKAGEGSVGGGLAVSP 113
            S    E  + ++ ++ L  +  G   G G  G G+A  P
Sbjct: 1684 SDHPLETISSASTLSSLSAEGGGSAGGGGGAGAGVASGP 1722



 Score = 35.4 bits (80), Expect = 0.030
 Identities = 32/91 (35%), Positives = 43/91 (47%), Gaps = 19/91 (20%)

Query: 46   PDPRPRTLPPLPPGPTPAQQPGRGLAEAAG-PRGSEGGNGSNPVAGLETDDHGGKAGEGS 104
            P PRP +LP LP GP        GL +  G P G  GG+ ++P A +    H G +  G 
Sbjct: 2013 PAPRPSSLPILPSGPLYP-----GLFDIRGSPTGGAGGS-ADPFAPVFVPPHPGIS--GG 2064

Query: 105  VGGGL-----AVSPN-----PGDKPMTQRAL 125
            +GG L     ++SP      P DKP   + L
Sbjct: 2065 LGGALSGASRSLSPTRLLSLPPDKPFGAKPL 2095



 Score = 32.7 bits (73), Expect = 0.19
 Identities = 31/94 (32%), Positives = 38/94 (40%), Gaps = 12/94 (12%)

Query: 46   PDPRPR---TLPPLPP----GPTPAQQPGR-GLAEAAGPRGSEGGNGSNPVAGLETDDHG 97
            P P+P      PP PP    G +P   P R  L      RG  GG G +P  G  +  H 
Sbjct: 1009 PPPQPHHHHAHPPHPPEMETGGSPDDPPPRLALGPQPSLRGWRGG-GPSPTPGAPSPSHH 1067

Query: 98   GKAGEGSVGGGLAVSPNPGDKPMTQRALTVLMVV 131
            G AG    GGG +  P      +  RA +  M V
Sbjct: 1068 GSAGG---GGGSSQGPALRYFQLPPRAASAAMYV 1098



 Score = 31.6 bits (70), Expect = 0.43
 Identities = 16/43 (37%), Positives = 23/43 (53%), Gaps = 1/43 (2%)

Query: 37   AEAAPGLGPPDPRPRTLPPLPPGPTPAQQPGRGLAEAAGPRGS 79
            +E  PG+ PP PR R++PP P  P  +++ G  L     P  S
Sbjct: 1512 SEDGPGVPPPSPR-RSVPPSPTSPRASEENGLPLLVLPPPAPS 1553



 Score = 30.8 bits (68), Expect = 0.73
 Identities = 22/73 (30%), Positives = 25/73 (34%), Gaps = 4/73 (5%)

Query: 45   PPDPRPRTLPPLPPGPTPAQQPGRGLAEAAGPRGSEGG----NGSNPVAGLETDDHGGKA 100
            PP P P   P  P GP       +  A   G    EGG            L TD      
Sbjct: 1208 PPSPSPVPTPASPSGPATLDFTSQFGAALVGAARREGGWQNEARRRSTLFLSTDAGDEDG 1267

Query: 101  GEGSVGGGLAVSP 113
            G+G +G G A  P
Sbjct: 1268 GDGGLGTGAAPGP 1280



 Score = 28.5 bits (62), Expect = 3.6
 Identities = 19/57 (33%), Positives = 22/57 (38%), Gaps = 1/57 (1%)

Query: 29  PLAVLLQAAEAAPGLGPPDPRPRTLPPLPPGPTPAQQPGRGLAEAAGPRGSEGGNGS 85
           P A+    + + PG     P P T PP PP  TP      G      PRG     GS
Sbjct: 903 PPAMKFSRSLSVPGSEDIPPPPTTSPPEPPYSTPPVPSSSGRL-TPSPRGGPFNPGS 958



 Score = 28.5 bits (62), Expect = 3.6
 Identities = 29/108 (26%), Positives = 35/108 (32%), Gaps = 30/108 (27%)

Query: 38   EAAPGLGPPDPRPR-TLPPLPP-----GPTPAQQPGRGLAEAAGPRGSEGGNGSNPV--- 88
            E   G  P DP PR  L P P      G  P+  PG       G  G  GG+   P    
Sbjct: 1025 EMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQGPALRY 1084

Query: 89   ---------AGLETDDHGGKA------------GEGSVGGGLAVSPNP 115
                     A +      G+             GE   GGGL  +P+P
Sbjct: 1085 FQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSP 1132



 Score = 27.7 bits (60), Expect = 6.2
 Identities = 25/83 (30%), Positives = 31/83 (37%), Gaps = 16/83 (19%)

Query: 54   PPLPPG-PTPAQQPGRGLAEAAGPRGSEGGNGSNP---------VAGLETDD------HG 97
            PP PP   TP++  GR L  + G R    G   +P         V G  TD         
Sbjct: 1745 PPYPPQLMTPSKLRGRALGASGGLRPGPSGGLRDPVTPTSPTVSVTGAGTDGLLALRACS 1804

Query: 98   GKAGEGSVGGGLAVSPNPGDKPM 120
            G    G  GG +AV P     P+
Sbjct: 1805 GPPTAGVAGGPVAVEPEVPPVPL 1827


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 35/107 (32%), Positives = 42/107 (39%), Gaps = 23/107 (21%)

Query: 39  AAPGLGPPDPRPRTLPPLPPGPT-------------PAQQPGR-GLAEAAGPRGSEGGNG 84
           AA  +GPP P     PP PPGP              PA +PG  G     GP G +G  G
Sbjct: 879 AAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPG 938

Query: 85  SNPVAGLE-TDDHGGKAGEGSVGG--------GLAVSPNPGDKPMTQ 122
           ++  AG   T    G AG+  V G        G    P P  +P  Q
Sbjct: 939 ADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQ 985



 Score = 35.4 bits (80), Expect = 0.030
 Identities = 29/80 (36%), Positives = 30/80 (37%), Gaps = 9/80 (11%)

Query: 39  AAPGLGPPDPRPRTLPPLPPGPTPAQQPGRGLAEAAGPRGSEGGNGSNPVAGLETDDHGG 98
           A    GPP P   T P  PPG  P     +G A   GPRGSEG  G     G       G
Sbjct: 327 ATGAAGPPGP---TGPAGPPG-FPGAVGAKGEAGPQGPRGSEGPQGVRGEPG-----PPG 377

Query: 99  KAGEGSVGGGLAVSPNPGDK 118
            AG     G       PG K
Sbjct: 378 PAGAAGPAGNPGADGQPGAK 397



 Score = 34.7 bits (78), Expect = 0.051
 Identities = 26/69 (37%), Positives = 30/69 (43%), Gaps = 11/69 (15%)

Query: 39  AAPG-LGPPDPRPRTLPPLPPGPT----PAQQPGR-GLAEAAGPRGSEGGNGSNPVAGLE 92
           + PG +GP  PR    PP  PGP     P  +PG  G +   GPRG  G  G N      
Sbjct: 176 SVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKN-----G 230

Query: 93  TDDHGGKAG 101
            D   GK G
Sbjct: 231 DDGEAGKPG 239



 Score = 33.1 bits (74), Expect = 0.15
 Identities = 27/72 (37%), Positives = 28/72 (38%), Gaps = 9/72 (12%)

Query: 54  PPLPPGPT-------PAQQPG-RGLAEAAGPRGSEGGNGSNPVAG-LETDDHGGKAGEGS 104
           PP P GP        PA  PG +GL   AGP G  G  G   V G L      G  GE  
Sbjct: 621 PPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERG 680

Query: 105 VGGGLAVSPNPG 116
             G   V   PG
Sbjct: 681 FPGERGVQGPPG 692



 Score = 32.3 bits (72), Expect = 0.25
 Identities = 27/83 (32%), Positives = 34/83 (40%), Gaps = 19/83 (22%)

Query: 29  PLAVLLQAAEAAPG----LGPPDPRPRTLPPLPPGPTPAQQPGRGLAEAAGPRGSEGGNG 84
           P A  L  +  +PG     GPP P  +   P PPGP P  +   G+    GP+G+ G   
Sbjct: 535 PGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGP-PGARGQAGVMGFPGPKGAAG--- 590

Query: 85  SNPVAGLETDDHGGKAGEGSVGG 107
                        GKAGE  V G
Sbjct: 591 -----------EPGKAGERGVPG 602



 Score = 31.2 bits (69), Expect = 0.56
 Identities = 33/93 (35%), Positives = 34/93 (36%), Gaps = 17/93 (18%)

Query: 37   AEAAPGL-GPPDP------RPRTLPPLPPGPTPAQQPGRGLAEAAGPRGSEGGNGSNPVA 89
            A  APG  GP  P      R  T P  P GP       RG A   GPRG +G  G     
Sbjct: 1047 APGAPGAPGPVGPAGKSGDRGETGPAGPAGPV-GPVGARGPAGPQGPRGDKGETG----- 1100

Query: 90   GLETDDHGGKAGEGSVGGGLAVSPNPGDKPMTQ 122
              E  D G K   G    GL   P P   P  Q
Sbjct: 1101 --EQGDRGIKGHRGF--SGLQGPPGPPGSPGEQ 1129



 Score = 27.7 bits (60), Expect = 6.2
 Identities = 18/37 (48%), Positives = 19/37 (51%), Gaps = 8/37 (21%)

Query: 41   PG-LGPPDPRPRT------LPPLPPGPT-PAQQPGRG 69
            PG +GPP PR RT       PP PPGP  P   P  G
Sbjct: 1159 PGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAG 1195



 Score = 27.3 bits (59), Expect = 8.1
 Identities = 29/80 (36%), Positives = 30/80 (37%), Gaps = 14/80 (17%)

Query: 44  GPPD----PRPRTLPPLPPGPTPAQQPG-RGLAEAAGPRGSEGGNGSNPVAGLETDDHGG 98
           GPP     P  R  P       P    G RG    AGP+GS G  G    AGL     G 
Sbjct: 482 GPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLP----GA 537

Query: 99  KAGEGSVGGGLAVSPNPGDK 118
           K   GS G     SP P  K
Sbjct: 538 KGLTGSPG-----SPGPDGK 552



 Score = 27.3 bits (59), Expect = 8.1
 Identities = 21/66 (31%), Positives = 29/66 (43%), Gaps = 7/66 (10%)

Query: 58  PGPTPAQQ----PG-RGLAEAAGPRGSEGGNGSNPVAGLETDDHGGKAGEGSVGGGLAVS 112
           PGP+ A+     PG RG+    GP G  G NG+    G + D   G  G     G   + 
Sbjct: 670 PGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGD--AGAPGAPGSQGAPGLQ 727

Query: 113 PNPGDK 118
             PG++
Sbjct: 728 GMPGER 733


>gi|54873613 agrin [Homo sapiens]
          Length = 2045

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 30/113 (26%), Positives = 43/113 (38%), Gaps = 19/113 (16%)

Query: 17   VLLLLLLPELSGPLAVLLQAAEAAPGLGPPDPRPRT--------------LPPLPPGPTP 62
            +LL   LP   G L +   +   +    PP  RPRT              +PP  P P P
Sbjct: 991  LLLSQALPAPPGALPLAPSSTAHSQTTPPPSSRPRTTASVPRTTVWPVLTVPPTAPSPAP 1050

Query: 63   AQQPGRGLAEAAGPRGSEGGNGSNPVAGLETDDHGGKAGEGSVGGGLAVSPNP 115
            +      +A A G  GS  G+    ++G +    GG  G   + G    +P P
Sbjct: 1051 SL-----VASAFGESGSTDGSSDEELSGDQEASGGGSGGLEPLEGSSVATPGP 1098


>gi|50428940 mediator complex subunit 25 [Homo sapiens]
          Length = 747

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 30/76 (39%), Positives = 34/76 (44%), Gaps = 14/76 (18%)

Query: 38  EAAPGLGPP---DPRPRTLPPLPPG---PTPAQQPGRGLAEAAGPRGSEGGNGSNPVAGL 91
           +AAPG+GPP    P P+ LPP PPG   P PA QP   L     P     G+G  P A  
Sbjct: 311 QAAPGVGPPFSQAPAPQ-LPPGPPGAPKPPPASQP--SLVSTVAP-----GSGLAPTAQP 362

Query: 92  ETDDHGGKAGEGSVGG 107
                 G    G V G
Sbjct: 363 GAPSMAGTVAPGGVSG 378



 Score = 28.1 bits (61), Expect = 4.8
 Identities = 19/51 (37%), Positives = 21/51 (41%), Gaps = 5/51 (9%)

Query: 42  GLGPPDPRPRTLPPLPPGPTPAQQPGRG-----LAEAAGPRGSEGGNGSNP 87
           GLG P   P  L P P    PAQ P R      +  + GPRG     G  P
Sbjct: 685 GLGQPQLGPPLLHPPPAQSWPAQLPPRAPLPGQMLLSGGPRGPVPQPGLQP 735


>gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]
          Length = 1604

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 31/88 (35%), Positives = 34/88 (38%), Gaps = 13/88 (14%)

Query: 37   AEAAPG-LGP---PDPRPRTLPPLPPGPTPAQQPGRGLAEAAGPRGSEGGNGSNPVAGLE 92
            AE  PG +GP   P P     PP PPG     QPG     A G +G  G  G   +AGL 
Sbjct: 1274 AEGEPGAMGPQGRPGPPGHVGPPGPPG-----QPGPAGISAVGLKGDRGATGERGLAGLP 1328

Query: 93   ----TDDHGGKAGEGSVGGGLAVSPNPG 116
                   H G  GE    G       PG
Sbjct: 1329 GQPGPPGHPGPPGEPGTDGAAGKEGPPG 1356



 Score = 33.5 bits (75), Expect = 0.11
 Identities = 25/68 (36%), Positives = 31/68 (45%), Gaps = 4/68 (5%)

Query: 41  PG-LGPPDPRPRTLPPLPPGPTPAQQPGRGLAEAAGPRGSEGGNGSNPVAGLETDDHGGK 99
           PG +GP        PP  PGP     PG    +  GP G +G  GS+ + G E    GGK
Sbjct: 437 PGFVGPEGLAGEPGPPGLPGPPGIGLPGTP-GDPGGPPGPKGDKGSSGIPGKE--GPGGK 493

Query: 100 AGEGSVGG 107
            G+  V G
Sbjct: 494 PGKPGVKG 501



 Score = 30.4 bits (67), Expect = 0.96
 Identities = 28/89 (31%), Positives = 32/89 (35%), Gaps = 12/89 (13%)

Query: 35  QAAEAAPGL----GPPDPRPRTLPPLPPGPTPAQ--QPGRGLAEAAGPRGSEGGNGSNPV 88
           Q    APGL    G P PR       PPGPT  +  Q   G+  A GP G  G + S P 
Sbjct: 793 QGEPGAPGLPGIQGLPGPRG------PPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPP 846

Query: 89  AGLETDDHGGKAGEGSVGGGLAVSPNPGD 117
                    G  G     G       PG+
Sbjct: 847 GRDGQQGQTGLRGTPGEKGPRGEKGEPGE 875



 Score = 29.6 bits (65), Expect = 1.6
 Identities = 28/101 (27%), Positives = 36/101 (35%), Gaps = 7/101 (6%)

Query: 23  LPELSGPLAVL-LQAAEAAPGLGPPDPRPRTLPPLPPG----PTPAQQPGRGLAEAAGPR 77
           LP + GP  +  +Q     PG G   P+     P  PG    P P   PG       G +
Sbjct: 766 LPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGP--TGEKGAQ 823

Query: 78  GSEGGNGSNPVAGLETDDHGGKAGEGSVGGGLAVSPNPGDK 118
           GS G  G+    G       G  G     G   +   PG+K
Sbjct: 824 GSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEK 864



 Score = 27.3 bits (59), Expect = 8.1
 Identities = 18/52 (34%), Positives = 25/52 (48%), Gaps = 1/52 (1%)

Query: 66  PGRGLAEAAGPRGSEGGNGSNPVAGLE-TDDHGGKAGEGSVGGGLAVSPNPG 116
           P   L  A GP+G +G +G+   +GL  +    G+ GE   GG   V   PG
Sbjct: 366 PDAPLQCAEGPKGEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPG 417


>gi|154816198 transcription elongation factor B polypeptide 3C-like
           [Homo sapiens]
          Length = 546

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 26/64 (40%), Positives = 33/64 (51%), Gaps = 6/64 (9%)

Query: 47  DPRPRTLP-PLPPGPTPA---QQPGRGLAEAA--GPRGSEGGNGSNPVAGLETDDHGGKA 100
           DP  RT P P+P GP PA   +QPGRG A AA  GP   +G  G      + +   G K+
Sbjct: 170 DPPTRTAPLPMPEGPEPAVPGEQPGRGHAHAAQGGPLLGQGCQGQPQGEAVGSHSKGHKS 229

Query: 101 GEGS 104
             G+
Sbjct: 230 SRGA 233


>gi|156938279 transcription elongation factor B polypeptide 3C [Homo
           sapiens]
          Length = 546

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 26/64 (40%), Positives = 33/64 (51%), Gaps = 6/64 (9%)

Query: 47  DPRPRTLP-PLPPGPTPA---QQPGRGLAEAA--GPRGSEGGNGSNPVAGLETDDHGGKA 100
           DP  RT P P+P GP PA   +QPGRG A AA  GP   +G  G      + +   G K+
Sbjct: 170 DPPTRTAPLPMPEGPEPAVPGEQPGRGHAHAAQGGPLLGQGCQGQPQGEAVGSHSKGHKS 229

Query: 101 GEGS 104
             G+
Sbjct: 230 SRGA 233


>gi|51479192 ring finger protein 1 [Homo sapiens]
          Length = 406

 Score = 39.3 bits (90), Expect = 0.002
 Identities = 28/89 (31%), Positives = 36/89 (40%), Gaps = 7/89 (7%)

Query: 34  LQAAEAAPGLGPPDPRP---RTLPPLPPGPTPAQQPGRGLAEAAGPRGSEGGNGSNPVAG 90
           +   E  PG G  D       + P   PGP P +  G G   A G     GG G+  V G
Sbjct: 169 MSGGEGEPGEGEGDGEDVSSDSAPDSAPGPAPKRPRGGG---AGGSSVGTGGGGTGGVGG 225

Query: 91  LETDDHGGKAGEGSVGGGLAVSPNPGDKP 119
               +  G  G G++GGG    P+P   P
Sbjct: 226 GAGSEDSGDRG-GTLGGGTLGPPSPPGAP 253


>gi|189339239 hypothetical protein LOC55009 [Homo sapiens]
          Length = 132

 Score = 39.3 bits (90), Expect = 0.002
 Identities = 51/177 (28%), Positives = 72/177 (40%), Gaps = 49/177 (27%)

Query: 13  LLASVLLLLLLPELSGPLAVLLQAAEAAPGLGPPDPRPRTLPPLPPGPTPAQQPGRGLAE 72
           +L   LLLLLL  L   LA L   AE A    P  P   TL P PP  T   QPG     
Sbjct: 5   VLQPPLLLLLLALL---LAALPCGAEEA---SPLRPAQVTLSP-PPAVTNGSQPG----- 52

Query: 73  AAGPRGSEGGNGSNPVAGLETDDHGGKAGEGSVGGGLAVSPNPGDKPMTQRALTVLMVVS 132
              P  S     + P               G+ G  L             R+  V++   
Sbjct: 53  --APHNS---THTRP--------------PGASGSALT------------RSFYVILGFC 81

Query: 133 GAVLVYFVVRTVRMRRRNRKTRRYGVLDTNIENMELTPLEQDDEDDDNTLFDANHPR 189
           G   +YF++R  R+++  R  RRYG+L    +  E+  L+ D+E    T+F++ + R
Sbjct: 82  GLTALYFLIRAFRLKKPQR--RRYGLLANTEDPTEMASLDSDEE----TVFESRNLR 132


>gi|122937424 one cut homeobox 3 [Homo sapiens]
          Length = 494

 Score = 39.3 bits (90), Expect = 0.002
 Identities = 40/121 (33%), Positives = 43/121 (35%), Gaps = 36/121 (29%)

Query: 23  LPELSGPLAVLLQAAEAAPGLGPPDPRPRTLPPL----PPG--------PTPAQQP---- 66
           LP +  PL+ L  A   A    P  P P   PPL    PPG        P  A +P    
Sbjct: 192 LPAMGSPLSPLPNALPPALHGAPQPPPPPPPPPLAAYGPPGHLAGDKLLPPAAFEPHAAL 251

Query: 67  --------GRGLAEAAGPRGSEGGNGSNPVAGL-----------ETDDHGGKAGEGSVGG 107
                    RGL    G  GS GG GS   AGL               HGG  G G  GG
Sbjct: 252 LGRAEDALARGLPGGGGGTGS-GGAGSGSAAGLLAPLGGLAAAGAHGPHGGGGGPGGSGG 310

Query: 108 G 108
           G
Sbjct: 311 G 311



 Score = 27.7 bits (60), Expect = 6.2
 Identities = 22/59 (37%), Positives = 28/59 (47%), Gaps = 1/59 (1%)

Query: 25  ELSGPLAVLLQAAEAAPGLGPPDPRPRTLPPLPPGPTPAQQPGRGLAEAAGPRGSEGGN 83
           EL+GPL   +  A  APGLG        L  LPP    A +  +  A AA   G+ GG+
Sbjct: 83  ELAGPLHPAMGMACEAPGLGGTYTTLTPLQHLPPLAAVADKFHQH-AAAAAVAGAHGGH 140


>gi|116008152 alpha 1 type XV collagen precursor [Homo sapiens]
          Length = 1388

 Score = 38.9 bits (89), Expect = 0.003
 Identities = 31/92 (33%), Positives = 38/92 (41%), Gaps = 7/92 (7%)

Query: 33  LLQAAEAAPGLGPPDPRPRTLPPLPPGP--TPAQQPGRGLAEAAGPRGSEGGNGSN---- 86
           L+ A     G  PPD  P  LP + P    TPAQ+   G+   AGP+G +G  G      
Sbjct: 518 LITAGGEESGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEELPGP 577

Query: 87  PVAGLETDDHGGKAGEGS-VGGGLAVSPNPGD 117
           P          G   EGS +G G  V    GD
Sbjct: 578 PEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGD 609



 Score = 33.5 bits (75), Expect = 0.11
 Identities = 27/89 (30%), Positives = 30/89 (33%), Gaps = 18/89 (20%)

Query: 44  GPPDPRPRTLPPLPPGPTPAQQPGRGLAEAAGPRGSEGGNG---------SNPVAGL--- 91
           GPP       PP PPGP     PG G     G   +EG            S P A +   
Sbjct: 712 GPPGVMGPPGPPGPPGP-----PGPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLK 766

Query: 92  -ETDDHGGKAGEGSVGGGLAVSPNPGDKP 119
            E  D G K   G  G  +   P P   P
Sbjct: 767 GEKGDRGPKGERGMDGASIVGPPGPRGPP 795



 Score = 31.6 bits (70), Expect = 0.43
 Identities = 33/132 (25%), Positives = 45/132 (34%), Gaps = 38/132 (28%)

Query: 24  PELSGPLAVLLQAAEAAPGLG----------------------PPDPRPRTLPPLPPGP- 60
           PE SGP+     A     GLG                      P  P P  LP +P  P 
Sbjct: 578 PEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPG 637

Query: 61  ---------TPAQQPGRGLAEAAGPRGSEGGNGSNPVAGLETDDHGGKAGEGSVG----- 106
                    +P +    G     GP G  G +G+  + G++  + G +   GSVG     
Sbjct: 638 TDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLPGMK-GEKGARGPNGSVGEKGDP 696

Query: 107 GGLAVSPNPGDK 118
           G   +   PG K
Sbjct: 697 GNRGLPGPPGKK 708



 Score = 31.2 bits (69), Expect = 0.56
 Identities = 26/65 (40%), Positives = 26/65 (40%), Gaps = 8/65 (12%)

Query: 28   GPLAVLLQAAEAAPGL-GPP------DPRPRTLPPLPPGPTPAQQPGRGLAEAAGPRGSE 80
            G   V  Q    APGL GPP      DP P   PP PPGP         L    GP G  
Sbjct: 1068 GETVVGPQGPPGAPGLPGPPGFGRPGDPGPPG-PPGPPGPPAILGAAVALPGPPGPPGQP 1126

Query: 81   GGNGS 85
            G  GS
Sbjct: 1127 GLPGS 1131



 Score = 27.7 bits (60), Expect = 6.2
 Identities = 22/71 (30%), Positives = 26/71 (36%), Gaps = 7/71 (9%)

Query: 54   PPLPPGPTPAQQPGRGLAEAAGPRGSEGGNGSNPVAGLETDDHG-----GKAGEGSVGGG 108
            P LP  P PA Q G  +    GP G+ G  G  P       D G     G  G  ++ G 
Sbjct: 1055 PGLPGNPGPAGQKGETVVGPQGPPGAPGLPG--PPGFGRPGDPGPPGPPGPPGPPAILGA 1112

Query: 109  LAVSPNPGDKP 119
                P P   P
Sbjct: 1113 AVALPGPPGPP 1123


>gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]
          Length = 1192

 Score = 38.9 bits (89), Expect = 0.003
 Identities = 32/102 (31%), Positives = 41/102 (40%), Gaps = 30/102 (29%)

Query: 44  GPP--DPRPRTLPPLP-------------PGPTPA---QQPGRGLAEAAGPRGSEGGNGS 85
           GPP   P P TLPP P             PGP P    + P  GL      RG EGG  S
Sbjct: 284 GPPAGSPPPLTLPPTPSPATAVTAASAQPPGPAPPITLEPPAPGLK-----RGREGGRAS 338

Query: 86  NP-------VAGLETDDHGGKAGEGSVGGGLAVSPNPGDKPM 120
                    ++G+ T   GG  G G + G  ++S   G + +
Sbjct: 339 TRDRKMLKFISGIFTKSTGGPPGSGPLPGPPSLSSGSGSREL 380



 Score = 35.0 bits (79), Expect = 0.039
 Identities = 29/97 (29%), Positives = 41/97 (42%), Gaps = 14/97 (14%)

Query: 34  LQAAEAAPGLGPPDPRPRTLPPLPPGPTPAQQPGRGLAEAAGPRGS--EGGNGSNPVAG- 90
           L  + ++ G G  +P   +  P  P    +  PGR L+  A P G    GG   +P  G 
Sbjct: 76  LWISTSSAGTGGAEPPALSPAPASPARPVSPAPGRRLSLWAVPPGPPLSGGLSPDPKPGG 135

Query: 91  ---------LETDDHGGKAGEGSVGGGL--AVSPNPG 116
                    L +   GG   EG  GGG+  + SP+PG
Sbjct: 136 APTSSRRPLLSSPSWGGPEPEGRAGGGIPGSSSPHPG 172



 Score = 30.4 bits (67), Expect = 0.96
 Identities = 16/36 (44%), Positives = 18/36 (50%)

Query: 52 TLPPLPPGPTPAQQPGRGLAEAAGPRGSEGGNGSNP 87
          TL  L   P P   P    A AAG RGSE G+  +P
Sbjct: 20 TLVKLESVPPPPPSPSAAAAGAAGARGSETGDPGSP 55



 Score = 28.5 bits (62), Expect = 3.6
 Identities = 28/99 (28%), Positives = 35/99 (35%), Gaps = 18/99 (18%)

Query: 35  QAAEAAPGLGPPDP-----RPRTLPPLPPGPTPAQQPGRGLAEAAGPRG---------SE 80
           +A    PG   P P     R +  PP PP P P +      A+A G +G         SE
Sbjct: 158 RAGGGIPGSSSPHPGTGSRRLKVAPP-PPAPKPCKTVTTSGAKAGGGKGAGSRLSWPESE 216

Query: 81  GG---NGSNPVAGLETDDHGGKAGEGSVGGGLAVSPNPG 116
           G     GS   AG             + GGG   S + G
Sbjct: 217 GKPRVKGSKSSAGTGASVSAAATAAAAGGGGSTASTSGG 255


>gi|31542493 D site of albumin promoter (albumin D-box) binding
           protein [Homo sapiens]
          Length = 325

 Score = 38.9 bits (89), Expect = 0.003
 Identities = 28/83 (33%), Positives = 33/83 (39%), Gaps = 10/83 (12%)

Query: 45  PPDPRPRTLPPLPPGP--TPAQQPGRGLAEAAGPRGSEG--------GNGSNPVAGLETD 94
           PP P P   P   P P  TPA  PG G   +A PR S G        G  S   AGL + 
Sbjct: 129 PPSPPPPGGPSPEPSPARTPAPSPGPGSCGSASPRSSPGHAPARAALGTASGHRAGLTSR 188

Query: 95  DHGGKAGEGSVGGGLAVSPNPGD 117
           D        +V   +   P+P D
Sbjct: 189 DTPSPVDPDTVEVLMTFEPDPAD 211


>gi|222136583 inositol polyphosphate phosphatase-like 1 [Homo sapiens]
          Length = 1258

 Score = 38.5 bits (88), Expect = 0.004
 Identities = 21/49 (42%), Positives = 27/49 (55%), Gaps = 3/49 (6%)

Query: 15   ASVLLLLLLPELSGPLAVLLQAAEAAPGLGPPDPRPRTLPPLPPGPTPA 63
            +++ L   L  L GP+      AEA    GPP P+    PPLPPGP+PA
Sbjct: 1061 SAIFLPPSLDPLPGPVVRGRGGAEAR---GPPPPKAHPRPPLPPGPSPA 1106



 Score = 27.7 bits (60), Expect = 6.2
 Identities = 20/58 (34%), Positives = 23/58 (39%), Gaps = 3/58 (5%)

Query: 25  ELSGPLAVLLQAAEAAPGLGPPDPRPRTLP---PLPPGPTPAQQPGRGLAEAAGPRGS 79
           E S PL+ L +  E  P  G P   PR  P   PL P   P   P      A  P+ S
Sbjct: 923 EASCPLSRLFEEPEKPPPTGRPPAPPRAAPREEPLTPRLKPEGAPEPEGVAAPPPKNS 980


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 38.5 bits (88), Expect = 0.004
 Identities = 28/80 (35%), Positives = 31/80 (38%), Gaps = 10/80 (12%)

Query: 39  AAPGLGPPDPRPRTLPPLPP---GPTPAQQ----PGRGLAEAAGPRGSEGG---NGSNPV 88
           A PG  PP P    +P  PP   GP P       PG G  +  GP G +GG    G  P 
Sbjct: 160 APPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPG 219

Query: 89  AGLETDDHGGKAGEGSVGGG 108
            G      GG       GGG
Sbjct: 220 GGPGLSTPGGHPKPPHRGGG 239



 Score = 33.1 bits (74), Expect = 0.15
 Identities = 27/86 (31%), Positives = 32/86 (37%), Gaps = 9/86 (10%)

Query: 39  AAPGLGP-PDPRPR-TLPPLPPGPTPAQQPGRGLAEAAGPRGSEGGNGSNPVAGLETDDH 96
           A PG GP P P P   +   PPG  P   P  G+         + G    P A +     
Sbjct: 141 APPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTP----PQAGGPPPPPAAVPGPGP 196

Query: 97  GGKAGE---GSVGGGLAVSPNPGDKP 119
           G K G    G  GG +   P PG  P
Sbjct: 197 GPKQGPGPGGPKGGKMPGGPKPGGGP 222



 Score = 28.5 bits (62), Expect = 3.6
 Identities = 23/86 (26%), Positives = 30/86 (34%), Gaps = 5/86 (5%)

Query: 35  QAAEAAPGLGPPDPRPRTLPPLPPGPTPAQQPGRGLAEAAGPRGSEG-----GNGSNPVA 89
           Q  +  P   PP   P   PP  P P   QQP     +++ P  ++G     G GS P A
Sbjct: 68  QQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPA 127

Query: 90  GLETDDHGGKAGEGSVGGGLAVSPNP 115
                           G G   +P P
Sbjct: 128 SSSAPPATPPTSGAPPGSGPGPTPTP 153


>gi|31657109 zinc finger protein 282 [Homo sapiens]
          Length = 671

 Score = 38.5 bits (88), Expect = 0.004
 Identities = 32/98 (32%), Positives = 38/98 (38%), Gaps = 20/98 (20%)

Query: 27  SGPLAVLLQAAEAAPGLGPPDPRPRTLPPLP---PGPTPAQQPGRGLAEAAGPRGSEG-- 81
           SGP   LL      P   PP P+P+  PP P     P P   P   +AE  G   S G  
Sbjct: 391 SGPSDSLLMVKNPPPA--PPQPQPQPQPPQPQLQSQPQPQSLPPIAVAENPGGPPSRGLL 448

Query: 82  -----------GNGSNPVAGLETDDHGGKAGEGSVGGG 108
                      G+G  P  G  +   GG  G+G  GGG
Sbjct: 449 DDGFQVLPGERGSGEAPPGGDRST--GGGGGDGGGGGG 484


>gi|23510333 pygopus homolog 2 [Homo sapiens]
          Length = 406

 Score = 38.5 bits (88), Expect = 0.004
 Identities = 30/104 (28%), Positives = 37/104 (35%), Gaps = 17/104 (16%)

Query: 28  GPLAVLLQAAEAAPGLGPPDPRPRTLPPLPP-GPTPAQQPGRGLAEA------------- 73
           GP+            LGPP    R   P  P GP+P Q+PG+GL                
Sbjct: 191 GPMISPTMGQPPRAELGPPSLSQRFAQPGAPFGPSPLQRPGQGLPSLPPNTSPFPGPDPG 250

Query: 74  -AGPRGSEGGNGSNPVA--GLETDDHGGKAGEGSVGGGLAVSPN 114
             GP G +GG   NP A      + H G       G   +  PN
Sbjct: 251 FPGPGGEDGGKPLNPPASTAFPQEPHSGSPAAAVNGNQPSFPPN 294



 Score = 31.2 bits (69), Expect = 0.56
 Identities = 28/100 (28%), Positives = 37/100 (37%), Gaps = 3/100 (3%)

Query: 26  LSGPLAVLLQAAEAAPGLGPPDPRPRTLPPLPPGPT-PA-QQPGRGLAEAAGPRGSEGGN 83
           + G +A  +    +  G G P P  R  PP PP P  PA   P +G         +    
Sbjct: 106 VQGGMAGQVPPGYSTGGGGGPQPLRRQPPPFPPNPMGPAFNMPPQGPGYPPPGNMNFPSQ 165

Query: 84  GSNPVAGLETDDHGGKAGEGSVGG-GLAVSPNPGDKPMTQ 122
             N   G       G+   G VGG G  +SP  G  P  +
Sbjct: 166 PFNQPLGQNFSPPSGQMMPGPVGGFGPMISPTMGQPPRAE 205


>gi|87239981 tankyrase, TRF1-interacting ankyrin-related
          ADP-ribose polymerase [Homo sapiens]
          Length = 1327

 Score = 38.1 bits (87), Expect = 0.005
 Identities = 21/45 (46%), Positives = 22/45 (48%), Gaps = 2/45 (4%)

Query: 35 QAAEAAPGLG--PPDPRPRTLPPLPPGPTPAQQPGRGLAEAAGPR 77
          Q  + APG    PP P P   P L PG TPA     GLA  A PR
Sbjct: 16 QQLQPAPGASAPPPPPPPPLSPGLAPGTTPASPTASGLAPFASPR 60


>gi|170016069 zinc finger, CCHC domain containing 2 [Homo sapiens]
          Length = 1178

 Score = 38.1 bits (87), Expect = 0.005
 Identities = 31/73 (42%), Positives = 32/73 (43%), Gaps = 13/73 (17%)

Query: 37  AEAAPGLGPPDPRPRTLPPLPPGPTPAQQPGRG-LAEAAGPRGSEGGNGSNPVAGLETDD 95
           A+A PG   P  R R   P PP P PA  P RG L     PRG        PVAG     
Sbjct: 25  ADARPGAKAPSRRRRDCRPPPPPPPPA-GPSRGPLPPPPPPRGL-----GPPVAG----- 73

Query: 96  HGGKAGEGSVGGG 108
            G  AG G  GGG
Sbjct: 74  -GAAAGAGMPGGG 85


>gi|118498339 EMI domain containing 2 [Homo sapiens]
          Length = 439

 Score = 38.1 bits (87), Expect = 0.005
 Identities = 26/62 (41%), Positives = 29/62 (46%), Gaps = 2/62 (3%)

Query: 44  GPPDPRPRTLPPLPPGPT-PAQQPGR-GLAEAAGPRGSEGGNGSNPVAGLETDDHGGKAG 101
           G P PR    PP PPGP  P   PG  G    AG RG+ G +G   V G E +      G
Sbjct: 300 GVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAEG 359

Query: 102 EG 103
           EG
Sbjct: 360 EG 361



 Score = 34.7 bits (78), Expect = 0.051
 Identities = 26/76 (34%), Positives = 30/76 (39%), Gaps = 6/76 (7%)

Query: 44  GPPDPRPRTLPPLPPGPTPAQQPGRGLAEAAGPRGSEGGNGSNPVAGLETDDHGGKAGEG 103
           GP  P  +T PP P GP P  +  RG     GP G  G  G     GL      G+ G  
Sbjct: 197 GPAGPPGQTGPPGPAGP-PGSKGDRGQTGEKGPAGPPGLLGPPGPRGLP-----GEMGRP 250

Query: 104 SVGGGLAVSPNPGDKP 119
              G    + NPG  P
Sbjct: 251 GPPGPPGPAGNPGPSP 266


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.137    0.413 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,763,943
Number of Sequences: 37866
Number of extensions: 658718
Number of successful extensions: 10792
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 400
Number of HSP's successfully gapped in prelim test: 795
Number of HSP's that attempted gapping in prelim test: 6423
Number of HSP's gapped (non-prelim): 4052
length of query: 190
length of database: 18,247,518
effective HSP length: 96
effective length of query: 94
effective length of database: 14,612,382
effective search space: 1373563908
effective search space used: 1373563908
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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