Guide to the Human Genome
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Search of human proteins with 37595553

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|37595553 ring finger protein 111 [Homo sapiens]
         (986 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|37595553 ring finger protein 111 [Homo sapiens]                   2039   0.0  
gi|57165361 ring finger protein 165 [Homo sapiens]                    258   3e-68
gi|56549656 ARKadia-like 1 isoform b [Homo sapiens]                   119   1e-26
gi|21450814 ARKadia-like 1 isoform a [Homo sapiens]                    99   2e-20
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          78   4e-14
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          78   4e-14
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          78   4e-14
gi|37577185 ring finger protein 38 isoform 2 [Homo sapiens]            75   4e-13
gi|37577181 ring finger protein 38 isoform 2 [Homo sapiens]            75   4e-13
gi|37577179 ring finger protein 38 isoform 3 [Homo sapiens]            75   4e-13
gi|37577177 ring finger protein 38 isoform 2 [Homo sapiens]            75   4e-13
gi|37577175 ring finger protein 38 isoform 1 [Homo sapiens]            75   4e-13
gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s...    73   2e-12
gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s...    73   2e-12
gi|7662486 ring finger protein 44 [Homo sapiens]                       72   2e-12
gi|29789407 ring finger protein 149 [Homo sapiens]                     69   3e-11
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ...    68   5e-11
gi|151301053 RNA binding motif protein 33 [Homo sapiens]               67   1e-10
gi|237757312 synaptojanin 1 isoform c [Homo sapiens]                   63   2e-09
gi|58331204 ring finger protein 150 [Homo sapiens]                     62   2e-09
gi|34452686 ring finger protein, LIM domain interacting [Homo sa...    61   5e-09
gi|34452684 ring finger protein, LIM domain interacting [Homo sa...    61   5e-09
gi|55750053 atrophin-1 [Homo sapiens]                                  61   5e-09
gi|55750041 atrophin-1 [Homo sapiens]                                  61   5e-09
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    60   8e-09
gi|209180481 Cas-Br-M (murine) ecotropic retroviral transforming...    60   1e-08
gi|7657520 ring finger protein 11 [Homo sapiens]                       60   1e-08
gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]            59   2e-08
gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]            59   2e-08
gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]            59   2e-08

>gi|37595553 ring finger protein 111 [Homo sapiens]
          Length = 986

 Score = 2039 bits (5283), Expect = 0.0
 Identities = 986/986 (100%), Positives = 986/986 (100%)

Query: 1   MSQWTPEYNELYTLKVDMKSEIPSDAPKTQESLKGILLHPEPIGAAKSFPAGVEMINSKV 60
           MSQWTPEYNELYTLKVDMKSEIPSDAPKTQESLKGILLHPEPIGAAKSFPAGVEMINSKV
Sbjct: 1   MSQWTPEYNELYTLKVDMKSEIPSDAPKTQESLKGILLHPEPIGAAKSFPAGVEMINSKV 60

Query: 61  GNEFSHLCDDSQKQEKEMNGNQQEQEKSLVVRKKRKSQQAGPSYVQNCVKENQGILGLRQ 120
           GNEFSHLCDDSQKQEKEMNGNQQEQEKSLVVRKKRKSQQAGPSYVQNCVKENQGILGLRQ
Sbjct: 61  GNEFSHLCDDSQKQEKEMNGNQQEQEKSLVVRKKRKSQQAGPSYVQNCVKENQGILGLRQ 120

Query: 121 HLGTPSDEDNDSSFSDCLSSPSSSLHFGDSDTVTSDEDKEVSVRHSQTILNAKSRSHSAR 180
           HLGTPSDEDNDSSFSDCLSSPSSSLHFGDSDTVTSDEDKEVSVRHSQTILNAKSRSHSAR
Sbjct: 121 HLGTPSDEDNDSSFSDCLSSPSSSLHFGDSDTVTSDEDKEVSVRHSQTILNAKSRSHSAR 180

Query: 181 SHKWPRTETESVSGLLMKRPCLHGSSLRRLPCRKRFVKNNSSQRTQKQKERILMQRKKRE 240
           SHKWPRTETESVSGLLMKRPCLHGSSLRRLPCRKRFVKNNSSQRTQKQKERILMQRKKRE
Sbjct: 181 SHKWPRTETESVSGLLMKRPCLHGSSLRRLPCRKRFVKNNSSQRTQKQKERILMQRKKRE 240

Query: 241 VLARRKYALLPSSSSSSENDLSSESSSSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDV 300
           VLARRKYALLPSSSSSSENDLSSESSSSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDV
Sbjct: 241 VLARRKYALLPSSSSSSENDLSSESSSSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDV 300

Query: 301 VVIEASSTPQVTANEEINVTSTDSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHASRPQ 360
           VVIEASSTPQVTANEEINVTSTDSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHASRPQ
Sbjct: 301 VVIEASSTPQVTANEEINVTSTDSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHASRPQ 360

Query: 361 EPRNRSRISTVIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSE 420
           EPRNRSRISTVIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSE
Sbjct: 361 EPRNRSRISTVIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSE 420

Query: 421 QASDTASAVTSSQPSTVSETSATLTSNSTTGTSIGDDSRRTTSSAVTETGPPAMPRLPSC 480
           QASDTASAVTSSQPSTVSETSATLTSNSTTGTSIGDDSRRTTSSAVTETGPPAMPRLPSC
Sbjct: 421 QASDTASAVTSSQPSTVSETSATLTSNSTTGTSIGDDSRRTTSSAVTETGPPAMPRLPSC 480

Query: 481 CPQHSPCGGSSQNHHALGHPHTSCFQQHGHHFQHHHHHHHTPHPAVPVSPSFSDPACPVE 540
           CPQHSPCGGSSQNHHALGHPHTSCFQQHGHHFQHHHHHHHTPHPAVPVSPSFSDPACPVE
Sbjct: 481 CPQHSPCGGSSQNHHALGHPHTSCFQQHGHHFQHHHHHHHTPHPAVPVSPSFSDPACPVE 540

Query: 541 RPPQVQAPCGANSSSGTSYHEQQALPVDLSNSGIRSHGSGSFHGASAFDPCCPVSSSRAA 600
           RPPQVQAPCGANSSSGTSYHEQQALPVDLSNSGIRSHGSGSFHGASAFDPCCPVSSSRAA
Sbjct: 541 RPPQVQAPCGANSSSGTSYHEQQALPVDLSNSGIRSHGSGSFHGASAFDPCCPVSSSRAA 600

Query: 601 IFGHQAAAAAPSQPLSSIDGYGSSMVAQPQPQPPPQPSLSSCRHYMPPPYASLTRPLHHQ 660
           IFGHQAAAAAPSQPLSSIDGYGSSMVAQPQPQPPPQPSLSSCRHYMPPPYASLTRPLHHQ
Sbjct: 601 IFGHQAAAAAPSQPLSSIDGYGSSMVAQPQPQPPPQPSLSSCRHYMPPPYASLTRPLHHQ 660

Query: 661 ASACPHSHGNPPPQTQPPPQVDYVIPHPVHAFHSQISSHATSHPVAPPPPTHLASTAAPI 720
           ASACPHSHGNPPPQTQPPPQVDYVIPHPVHAFHSQISSHATSHPVAPPPPTHLASTAAPI
Sbjct: 661 ASACPHSHGNPPPQTQPPPQVDYVIPHPVHAFHSQISSHATSHPVAPPPPTHLASTAAPI 720

Query: 721 PQHLPPTHQPISHHIPATAPPAQRLHPHEVMQRMEVQRRRMMQHPTRAHERPPPHPHRMH 780
           PQHLPPTHQPISHHIPATAPPAQRLHPHEVMQRMEVQRRRMMQHPTRAHERPPPHPHRMH
Sbjct: 721 PQHLPPTHQPISHHIPATAPPAQRLHPHEVMQRMEVQRRRMMQHPTRAHERPPPHPHRMH 780

Query: 781 PNYGHGHHIHVPQTMSSHPRQAPERSAWELGIEAGVTAATYTPGALHPHLAHYHAPPRLH 840
           PNYGHGHHIHVPQTMSSHPRQAPERSAWELGIEAGVTAATYTPGALHPHLAHYHAPPRLH
Sbjct: 781 PNYGHGHHIHVPQTMSSHPRQAPERSAWELGIEAGVTAATYTPGALHPHLAHYHAPPRLH 840

Query: 841 HLQLGALPLMVPDMAGYPHIRYISSGLDGTSFRGPFRGNFEELIHLEERLGNVNRGASQG 900
           HLQLGALPLMVPDMAGYPHIRYISSGLDGTSFRGPFRGNFEELIHLEERLGNVNRGASQG
Sbjct: 841 HLQLGALPLMVPDMAGYPHIRYISSGLDGTSFRGPFRGNFEELIHLEERLGNVNRGASQG 900

Query: 901 TIERCTYPHKYKKRKLHCKQDGEEGTEEDTEEKCTICLSILEEGEDVRRLPCMHLFHQVC 960
           TIERCTYPHKYKKRKLHCKQDGEEGTEEDTEEKCTICLSILEEGEDVRRLPCMHLFHQVC
Sbjct: 901 TIERCTYPHKYKKRKLHCKQDGEEGTEEDTEEKCTICLSILEEGEDVRRLPCMHLFHQVC 960

Query: 961 VDQWLITNKKCPICRVDIEAQLPSES 986
           VDQWLITNKKCPICRVDIEAQLPSES
Sbjct: 961 VDQWLITNKKCPICRVDIEAQLPSES 986


>gi|57165361 ring finger protein 165 [Homo sapiens]
          Length = 346

 Score =  258 bits (658), Expect = 3e-68
 Identities = 148/349 (42%), Positives = 201/349 (57%), Gaps = 37/349 (10%)

Query: 651 ASLTRPLHHQASACPHSHGNPPPQTQPPPQVDYVIPHPVHAFHSQISSHATSHPVAPPPP 710
           A   R  H  A++C H H  PP   Q  P  D+ + HPV +    +S+H          P
Sbjct: 22  APFQRSQHPHATSCRHFHLGPPQPQQLAP--DFPLAHPVQS-QPGLSAHMA--------P 70

Query: 711 THLASTAAPIPQHLPPTHQPISHHIPATAPP--AQRLHPHEVMQR--MEVQRRRMMQHPT 766
            H  S A     H   T  P       T P    Q LH   ++Q+  +E Q RR++ HP 
Sbjct: 71  AHQHSGAL----HQSLTPLPTLQFQDVTGPSFLPQALHQQYLLQQQLLEAQHRRLVSHPR 126

Query: 767 RAHERPPPHPHRMHPNYGHGHHIHVPQTMSSHPRQAPERSAWELGIEAGVTAATYTPGAL 826
           R+ ER   HPHR+HP++  G      Q  +  PR   E + W+L ++AG++ A +    +
Sbjct: 127 RSQERVSVHPHRLHPSFDFG------QLQTPQPRYLAEGTDWDLSVDAGLSPAQFQVRPI 180

Query: 827 HPHLAHYHAPPRLHHL--QLGALPLMVPDMAGYPH--IRYIS-SGLDGTSFRGPFRGNFE 881
             H  HY A PR+HH      +  ++V ++  YP+  + +++  GL+ +      R ++E
Sbjct: 181 PQHYQHYLATPRMHHFPRNSSSTQMVVHEIRNYPYPQLHFLALQGLNPSRHTSAVRESYE 240

Query: 882 ELIHLEERLGNVNRGASQGTIERCTYPHKYKKRKLHCKQDG----EEGTEEDTEEKCTIC 937
           EL+ LE+RLGNV RGA Q TIER T+PHKYKKR+    QDG    +EG E DT+EKCTIC
Sbjct: 241 ELLQLEDRLGNVTRGAVQNTIERFTFPHKYKKRR---PQDGKGKKDEGEESDTDEKCTIC 297

Query: 938 LSILEEGEDVRRLPCMHLFHQVCVDQWLITNKKCPICRVDIEAQLPSES 986
           LS+LE+GEDVRRLPCMHLFHQ+CVDQWL  +KKCPICRVDIE QL ++S
Sbjct: 298 LSMLEDGEDVRRLPCMHLFHQLCVDQWLAMSKKCPICRVDIETQLGADS 346


>gi|56549656 ARKadia-like 1 isoform b [Homo sapiens]
          Length = 343

 Score =  119 bits (299), Expect = 1e-26
 Identities = 94/265 (35%), Positives = 141/265 (53%), Gaps = 17/265 (6%)

Query: 129 DNDSSFSDCLSSPSSSLHFGDSDTVTSDEDKEVSVRHSQTILNAKSRSHSARSHKWPRTE 188
           ++DSS + C+ SPSSS H  DSDT++S E+ E S   +    +    S +    K  R+ 
Sbjct: 86  ESDSS-NHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGATVGRKSRRSR 144

Query: 189 TESVSGLLMKRPCLHGSSLRRLPCRKRFVKNNSSQRTQKQKERILMQRKKREVLARRKYA 248
           +ES +  +  +     S  +     K  VK +   R+QK KERI + R+KRE  AR+KY 
Sbjct: 145 SESETSTMAAKKNRQSSDKQNGRVAK--VKGH---RSQKHKERIRLLRQKREAAARKKYN 199

Query: 249 LLPSSSSSSENDLSSESSSSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASST 308
           LL   SS+S++DL+ +SS+SSS + EE      S + +   A   G +D   +  + +S 
Sbjct: 200 LL-QDSSTSDSDLTCDSSTSSSDDDEE-----VSGSSKTITAEIPGHLDPGFLASDKTSA 253

Query: 309 PQVTANEEINVTSTDSEVEIVTVGESYR---SRSTLGHSRSHWSQGSSSHASRPQEPRNR 365
                NEEIN+ S+DSEVEIV V E  R    R  +  S S W  GS +     ++ ++ 
Sbjct: 254 GNAPLNEEINIASSDSEVEIVGVQEHARCVHPRGGVIQSVSSWKHGSGTQYVSTRQTQSW 313

Query: 366 SRISTVIQPLRQNAAEVVDLTVDED 390
           + ++   Q    + AEVVDLT+DED
Sbjct: 314 TAVTP--QQTWASPAEVVDLTLDED 336



 Score = 38.5 bits (88), Expect = 0.031
 Identities = 27/104 (25%), Positives = 54/104 (51%), Gaps = 5/104 (4%)

Query: 366 SRISTVIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSEQASDT 425
           S +  ++  LR++++E    + + D+PT    T    ES +++  + + + S     SDT
Sbjct: 53  SSMPCLLMELRRDSSESQLASTESDKPT----TGRVYESDSSNHCMLSPSSSGHLADSDT 108

Query: 426 ASAVTSSQPSTVSETSATLTSNSTTGTSIGDDSRRTTSSAVTET 469
            S+   ++PS  +ET+     +  +G ++G  SRR+ S + T T
Sbjct: 109 LSSAEENEPSQ-AETAVEGDPSGVSGATVGRKSRRSRSESETST 151


>gi|21450814 ARKadia-like 1 isoform a [Homo sapiens]
          Length = 404

 Score = 99.0 bits (245), Expect = 2e-20
 Identities = 96/321 (29%), Positives = 149/321 (46%), Gaps = 68/321 (21%)

Query: 129 DNDSSFSDCLSSPSSSLHFGDSDTVTSDEDKEVSVRHSQTILNAKSRSHSARSHKWPRTE 188
           ++DSS + C+ SPSSS H  DSDT++S E+ E S   +    +    S +    K  R+ 
Sbjct: 86  ESDSS-NHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGATVGRKSRRSR 144

Query: 189 TESVSGLLMKRPCLHGSSLRRLPCRKRFVKNNSSQRTQKQKERILMQRKKREVLARRKYA 248
           +ES +  +  +     S  +     K  VK +   R+QK KERI + R+KRE  AR+KY 
Sbjct: 145 SESETSTMAAKKNRQSSDKQNGRVAK--VKGH---RSQKHKERIRLLRQKREAAARKKYN 199

Query: 249 LLPSSSSSSENDLSSESSSSSSTEGEE--------------------------------- 275
           LL   SS+S++DL+ +SS+SSS + EE                                 
Sbjct: 200 LL-QDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPDGPPVVAHYDMSDTNSDPEV 258

Query: 276 ---DLFVSASENHQNNPAV----------PSGSIDE----------DVVVIEASSTPQVT 312
              D  ++A+   +++ +V           SG ++E            +  + +S     
Sbjct: 259 VNVDNLLAAAVVQEHSNSVGGQDTGATWRTSGLLEELNAEAGHLDPGFLASDKTSAGNAP 318

Query: 313 ANEEINVTSTDSEVEIVTVGESYR---SRSTLGHSRSHWSQGSSSHASRPQEPRNRSRIS 369
            NEEIN+ S+DSEVEIV V E  R    R  +  S S W  GS +     ++ ++ + ++
Sbjct: 319 LNEEINIASSDSEVEIVGVQEHARCVHPRGGVIQSVSSWKHGSGTQYVSTRQTQSWTAVT 378

Query: 370 TVIQPLRQNAAEVVDLTVDED 390
              Q    + AEVVDLT+DED
Sbjct: 379 P--QQTWASPAEVVDLTLDED 397



 Score = 38.5 bits (88), Expect = 0.031
 Identities = 27/104 (25%), Positives = 54/104 (51%), Gaps = 5/104 (4%)

Query: 366 SRISTVIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSEQASDT 425
           S +  ++  LR++++E    + + D+PT    T    ES +++  + + + S     SDT
Sbjct: 53  SSMPCLLMELRRDSSESQLASTESDKPT----TGRVYESDSSNHCMLSPSSSGHLADSDT 108

Query: 426 ASAVTSSQPSTVSETSATLTSNSTTGTSIGDDSRRTTSSAVTET 469
            S+   ++PS  +ET+     +  +G ++G  SRR+ S + T T
Sbjct: 109 LSSAEENEPSQ-AETAVEGDPSGVSGATVGRKSRRSRSESETST 151


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 78.2 bits (191), Expect = 4e-14
 Identities = 135/571 (23%), Positives = 203/571 (35%), Gaps = 132/571 (23%)

Query: 251 PSSSSSSENDLSSESSSSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASSTPQ 310
           PS++S+S ND  +E+   S+ + +E+       N +    V S + + D       ++ +
Sbjct: 60  PSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEAD------RTSSK 113

Query: 311 VTANEEINVTSTDSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSRIST 370
            T  +EI+  ++ SE E    GES  SRS          +GSS       +P++      
Sbjct: 114 KTKTQEISRPNSPSEGE----GESSDSRSVN-------DEGSS-------DPKD------ 149

Query: 371 VIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSEQASDTASAVT 430
                           +D+D             +++TS SI +   + S+  S     + 
Sbjct: 150 ----------------IDQD-------------NRSTSPSIPSPQDNESDSDSSAQQQML 180

Query: 431 SSQPSTVSETSATLTSNSTTGTSIGDDSRRTTSSAVTETGPPAMPRLPSCCPQHSPCGGS 490
            +QP  +          + TG +    S    +  +   GP   P   +  PQ SP    
Sbjct: 181 QAQPPALQ---------APTGVTPAPSSAPPGTPQLPTPGPT--PSATAVPPQGSPTASQ 229

Query: 491 SQNHHALGH---PHTSCFQQHGHHFQH----HHHHHHTPHPAV-PVSPSFSDPACPVERP 542
           + N         PHT   Q    H Q     H   H +PHP + P++ S   P+ P    
Sbjct: 230 APNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQ 289

Query: 543 PQV--QAPCGANSSSGTSYHEQQALPVDLSNSGIRSHGSGSFHGASAFDPCCPVSSSRAA 600
           P +  Q P G         H  QA P+      ++  G     G        P +S   A
Sbjct: 290 PPLHGQGPPGP--------HSLQAGPL------LQHPGPPQPFGLP------PQASQGQA 329

Query: 601 IFGHQAAAAAPSQPLSSIDGYGSSMVAQPQPQPPPQPSLSSCRHYMPPPYASLTRPLHHQ 660
             G   AAA P   L       +    QP  + P  P+  +  H  PPP    T P+   
Sbjct: 330 PLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPP----TTPIPQL 385

Query: 661 ASACPHSHGNPPPQTQPPP-QVDYVIPHPVHAFHSQISSHATSH-PVAPPPPTHLASTAA 718
            +  P +H +PP  + P P  ++  +P P       +SS +T H P A PPP  L   + 
Sbjct: 386 PA--PQAHKHPPHLSGPSPFSMNANLPPPPAL--KPLSSLSTHHPPSAHPPPLQLMPQSQ 441

Query: 719 PIPQHLPPTHQPISHHIPATAPPAQRLHPHEVMQRMEVQRRRMMQHPTRAHERPPPHPHR 778
           P+P       QP         PP    HP                 PT  H+  P  P  
Sbjct: 442 PLPS---SPAQPPGLTQSQNLPPPPASHP-----------------PTGLHQVAPQPPFA 481

Query: 779 MHPNYGHGHHIHVPQT--MSSHPRQAPERSA 807
            HP    G     P T   +S P   P  SA
Sbjct: 482 QHPFVPGGPPPITPPTCPSTSTPPAGPGTSA 512



 Score = 34.7 bits (78), Expect = 0.45
 Identities = 46/158 (29%), Positives = 54/158 (34%), Gaps = 42/158 (26%)

Query: 695 QISSHATSHPVAPPPPTHLASTAAPIPQH--LPPTHQPISHHIP--ATAPPAQRLHPHEV 750
           Q  +  T  P + PP T    T  P P    +PP   P +   P    AP A   H H  
Sbjct: 188 QAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTH-- 245

Query: 751 MQRMEVQRRRMMQHPTRAHE-RPPPHPHRMHPNYGHGHHIHVPQTMSSHPRQAPERSAWE 809
                +Q+   + HP R     PPPHP                   S HP   P      
Sbjct: 246 -----IQQAPAL-HPQRPPSPHPPPHP-------------------SPHPPLQP------ 274

Query: 810 LGIEAGVTAATYTPGALHPHLAHYHAPPRLHHLQLGAL 847
           L   AG  +A   P    P L H   PP  H LQ G L
Sbjct: 275 LTGSAGQPSA---PSHAQPPL-HGQGPPGPHSLQAGPL 308


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 78.2 bits (191), Expect = 4e-14
 Identities = 135/571 (23%), Positives = 203/571 (35%), Gaps = 132/571 (23%)

Query: 251  PSSSSSSENDLSSESSSSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASSTPQ 310
            PS++S+S ND  +E+   S+ + +E+       N +    V S + + D       ++ +
Sbjct: 614  PSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEAD------RTSSK 667

Query: 311  VTANEEINVTSTDSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSRIST 370
             T  +EI+  ++ SE E    GES  SRS          +GSS       +P++      
Sbjct: 668  KTKTQEISRPNSPSEGE----GESSDSRSVN-------DEGSS-------DPKD------ 703

Query: 371  VIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSEQASDTASAVT 430
                            +D+D             +++TS SI +   + S+  S     + 
Sbjct: 704  ----------------IDQD-------------NRSTSPSIPSPQDNESDSDSSAQQQML 734

Query: 431  SSQPSTVSETSATLTSNSTTGTSIGDDSRRTTSSAVTETGPPAMPRLPSCCPQHSPCGGS 490
             +QP  +          + TG +    S    +  +   GP   P   +  PQ SP    
Sbjct: 735  QAQPPALQ---------APTGVTPAPSSAPPGTPQLPTPGPT--PSATAVPPQGSPTASQ 783

Query: 491  SQNHHALGH---PHTSCFQQHGHHFQH----HHHHHHTPHPAV-PVSPSFSDPACPVERP 542
            + N         PHT   Q    H Q     H   H +PHP + P++ S   P+ P    
Sbjct: 784  APNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQ 843

Query: 543  PQV--QAPCGANSSSGTSYHEQQALPVDLSNSGIRSHGSGSFHGASAFDPCCPVSSSRAA 600
            P +  Q P G         H  QA P+      ++  G     G        P +S   A
Sbjct: 844  PPLHGQGPPGP--------HSLQAGPL------LQHPGPPQPFGLP------PQASQGQA 883

Query: 601  IFGHQAAAAAPSQPLSSIDGYGSSMVAQPQPQPPPQPSLSSCRHYMPPPYASLTRPLHHQ 660
              G   AAA P   L       +    QP  + P  P+  +  H  PPP    T P+   
Sbjct: 884  PLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPP----TTPIPQL 939

Query: 661  ASACPHSHGNPPPQTQPPP-QVDYVIPHPVHAFHSQISSHATSH-PVAPPPPTHLASTAA 718
             +  P +H +PP  + P P  ++  +P P       +SS +T H P A PPP  L   + 
Sbjct: 940  PA--PQAHKHPPHLSGPSPFSMNANLPPPPAL--KPLSSLSTHHPPSAHPPPLQLMPQSQ 995

Query: 719  PIPQHLPPTHQPISHHIPATAPPAQRLHPHEVMQRMEVQRRRMMQHPTRAHERPPPHPHR 778
            P+P       QP         PP    HP                 PT  H+  P  P  
Sbjct: 996  PLPS---SPAQPPGLTQSQNLPPPPASHP-----------------PTGLHQVAPQPPFA 1035

Query: 779  MHPNYGHGHHIHVPQT--MSSHPRQAPERSA 807
             HP    G     P T   +S P   P  SA
Sbjct: 1036 QHPFVPGGPPPITPPTCPSTSTPPAGPGTSA 1066



 Score = 34.7 bits (78), Expect = 0.45
 Identities = 46/158 (29%), Positives = 54/158 (34%), Gaps = 42/158 (26%)

Query: 695 QISSHATSHPVAPPPPTHLASTAAPIPQH--LPPTHQPISHHIP--ATAPPAQRLHPHEV 750
           Q  +  T  P + PP T    T  P P    +PP   P +   P    AP A   H H  
Sbjct: 742 QAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTH-- 799

Query: 751 MQRMEVQRRRMMQHPTRAHE-RPPPHPHRMHPNYGHGHHIHVPQTMSSHPRQAPERSAWE 809
                +Q+   + HP R     PPPHP                   S HP   P      
Sbjct: 800 -----IQQAPAL-HPQRPPSPHPPPHP-------------------SPHPPLQP------ 828

Query: 810 LGIEAGVTAATYTPGALHPHLAHYHAPPRLHHLQLGAL 847
           L   AG  +A   P    P L H   PP  H LQ G L
Sbjct: 829 LTGSAGQPSA---PSHAQPPL-HGQGPPGPHSLQAGPL 862


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 78.2 bits (191), Expect = 4e-14
 Identities = 135/571 (23%), Positives = 203/571 (35%), Gaps = 132/571 (23%)

Query: 251  PSSSSSSENDLSSESSSSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASSTPQ 310
            PS++S+S ND  +E+   S+ + +E+       N +    V S + + D       ++ +
Sbjct: 614  PSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEAD------RTSSK 667

Query: 311  VTANEEINVTSTDSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSRIST 370
             T  +EI+  ++ SE E    GES  SRS          +GSS       +P++      
Sbjct: 668  KTKTQEISRPNSPSEGE----GESSDSRSVN-------DEGSS-------DPKD------ 703

Query: 371  VIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSEQASDTASAVT 430
                            +D+D             +++TS SI +   + S+  S     + 
Sbjct: 704  ----------------IDQD-------------NRSTSPSIPSPQDNESDSDSSAQQQML 734

Query: 431  SSQPSTVSETSATLTSNSTTGTSIGDDSRRTTSSAVTETGPPAMPRLPSCCPQHSPCGGS 490
             +QP  +          + TG +    S    +  +   GP   P   +  PQ SP    
Sbjct: 735  QAQPPALQ---------APTGVTPAPSSAPPGTPQLPTPGPT--PSATAVPPQGSPTASQ 783

Query: 491  SQNHHALGH---PHTSCFQQHGHHFQH----HHHHHHTPHPAV-PVSPSFSDPACPVERP 542
            + N         PHT   Q    H Q     H   H +PHP + P++ S   P+ P    
Sbjct: 784  APNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQ 843

Query: 543  PQV--QAPCGANSSSGTSYHEQQALPVDLSNSGIRSHGSGSFHGASAFDPCCPVSSSRAA 600
            P +  Q P G         H  QA P+      ++  G     G        P +S   A
Sbjct: 844  PPLHGQGPPGP--------HSLQAGPL------LQHPGPPQPFGLP------PQASQGQA 883

Query: 601  IFGHQAAAAAPSQPLSSIDGYGSSMVAQPQPQPPPQPSLSSCRHYMPPPYASLTRPLHHQ 660
              G   AAA P   L       +    QP  + P  P+  +  H  PPP    T P+   
Sbjct: 884  PLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPP----TTPIPQL 939

Query: 661  ASACPHSHGNPPPQTQPPP-QVDYVIPHPVHAFHSQISSHATSH-PVAPPPPTHLASTAA 718
             +  P +H +PP  + P P  ++  +P P       +SS +T H P A PPP  L   + 
Sbjct: 940  PA--PQAHKHPPHLSGPSPFSMNANLPPPPAL--KPLSSLSTHHPPSAHPPPLQLMPQSQ 995

Query: 719  PIPQHLPPTHQPISHHIPATAPPAQRLHPHEVMQRMEVQRRRMMQHPTRAHERPPPHPHR 778
            P+P       QP         PP    HP                 PT  H+  P  P  
Sbjct: 996  PLPS---SPAQPPGLTQSQNLPPPPASHP-----------------PTGLHQVAPQPPFA 1035

Query: 779  MHPNYGHGHHIHVPQT--MSSHPRQAPERSA 807
             HP    G     P T   +S P   P  SA
Sbjct: 1036 QHPFVPGGPPPITPPTCPSTSTPPAGPGTSA 1066



 Score = 34.7 bits (78), Expect = 0.45
 Identities = 46/158 (29%), Positives = 54/158 (34%), Gaps = 42/158 (26%)

Query: 695 QISSHATSHPVAPPPPTHLASTAAPIPQH--LPPTHQPISHHIP--ATAPPAQRLHPHEV 750
           Q  +  T  P + PP T    T  P P    +PP   P +   P    AP A   H H  
Sbjct: 742 QAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTH-- 799

Query: 751 MQRMEVQRRRMMQHPTRAHE-RPPPHPHRMHPNYGHGHHIHVPQTMSSHPRQAPERSAWE 809
                +Q+   + HP R     PPPHP                   S HP   P      
Sbjct: 800 -----IQQAPAL-HPQRPPSPHPPPHP-------------------SPHPPLQP------ 828

Query: 810 LGIEAGVTAATYTPGALHPHLAHYHAPPRLHHLQLGAL 847
           L   AG  +A   P    P L H   PP  H LQ G L
Sbjct: 829 LTGSAGQPSA---PSHAQPPL-HGQGPPGPHSLQAGPL 862


>gi|37577185 ring finger protein 38 isoform 2 [Homo sapiens]
          Length = 432

 Score = 74.7 bits (182), Expect = 4e-13
 Identities = 79/281 (28%), Positives = 106/281 (37%), Gaps = 40/281 (14%)

Query: 704 PVAPPPPTHLASTAAPIPQHLPPTHQPISHHIPATAP--PAQRLHPHEVMQRMEVQRRRM 761
           P A  PP   +      P HL P H P   H+P      P Q       +QR+E +   +
Sbjct: 176 PYAAFPPLISSDPFLIHPPHLSPHHPP---HLPPPGQFVPFQTQQSRSPLQRIENEVELL 232

Query: 762 MQH-PTRAHERPPP-HPHRMHPNYGHGHHIHVP--QTMSSHPRQAPERSAWELGIEAGVT 817
            +H P      PP  HP  + P+       H P  Q +S      P       G     +
Sbjct: 233 GEHLPVGGFTYPPSAHPPTLPPSAPLQFLTHDPLHQEVSFGVPYPPFMPRRLTGRSRYRS 292

Query: 818 AATYTPGALHPHLAHYHAPPRLHHLQLGALPLMVPDMAGYPHIRYISSGLDGTSFRGPFR 877
                P   HP L  Y          L  LP  VP   G P   +     DG        
Sbjct: 293 QQPIPPPPYHPSLLPY---------VLSMLP--VPPAVG-PTFSFELDVEDGEV------ 334

Query: 878 GNFEELIHLEERLGNVN-RGASQGTIERCTYPHKYKKRKLHCKQDGEEGTEEDTEEKCTI 936
            N+E L++L ERLG    RG ++  IE+      Y+               +  +  C +
Sbjct: 335 ENYEALLNLAERLGEAKPRGLTKADIEQLP---SYRFNP---------NNHQSEQTLCVV 382

Query: 937 CLSILEEGEDVRRLPCMHLFHQVCVDQWLITNKKCPICRVD 977
           C+   E  + +R LPC H FH  CVD+WL  N+ CPICR D
Sbjct: 383 CMCDFESRQLLRVLPCNHEFHAKCVDKWLKANRTCPICRAD 423


>gi|37577181 ring finger protein 38 isoform 2 [Homo sapiens]
          Length = 432

 Score = 74.7 bits (182), Expect = 4e-13
 Identities = 79/281 (28%), Positives = 106/281 (37%), Gaps = 40/281 (14%)

Query: 704 PVAPPPPTHLASTAAPIPQHLPPTHQPISHHIPATAP--PAQRLHPHEVMQRMEVQRRRM 761
           P A  PP   +      P HL P H P   H+P      P Q       +QR+E +   +
Sbjct: 176 PYAAFPPLISSDPFLIHPPHLSPHHPP---HLPPPGQFVPFQTQQSRSPLQRIENEVELL 232

Query: 762 MQH-PTRAHERPPP-HPHRMHPNYGHGHHIHVP--QTMSSHPRQAPERSAWELGIEAGVT 817
            +H P      PP  HP  + P+       H P  Q +S      P       G     +
Sbjct: 233 GEHLPVGGFTYPPSAHPPTLPPSAPLQFLTHDPLHQEVSFGVPYPPFMPRRLTGRSRYRS 292

Query: 818 AATYTPGALHPHLAHYHAPPRLHHLQLGALPLMVPDMAGYPHIRYISSGLDGTSFRGPFR 877
                P   HP L  Y          L  LP  VP   G P   +     DG        
Sbjct: 293 QQPIPPPPYHPSLLPY---------VLSMLP--VPPAVG-PTFSFELDVEDGEV------ 334

Query: 878 GNFEELIHLEERLGNVN-RGASQGTIERCTYPHKYKKRKLHCKQDGEEGTEEDTEEKCTI 936
            N+E L++L ERLG    RG ++  IE+      Y+               +  +  C +
Sbjct: 335 ENYEALLNLAERLGEAKPRGLTKADIEQLP---SYRFNP---------NNHQSEQTLCVV 382

Query: 937 CLSILEEGEDVRRLPCMHLFHQVCVDQWLITNKKCPICRVD 977
           C+   E  + +R LPC H FH  CVD+WL  N+ CPICR D
Sbjct: 383 CMCDFESRQLLRVLPCNHEFHAKCVDKWLKANRTCPICRAD 423


>gi|37577179 ring finger protein 38 isoform 3 [Homo sapiens]
          Length = 465

 Score = 74.7 bits (182), Expect = 4e-13
 Identities = 79/281 (28%), Positives = 106/281 (37%), Gaps = 40/281 (14%)

Query: 704 PVAPPPPTHLASTAAPIPQHLPPTHQPISHHIPATAP--PAQRLHPHEVMQRMEVQRRRM 761
           P A  PP   +      P HL P H P   H+P      P Q       +QR+E +   +
Sbjct: 209 PYAAFPPLISSDPFLIHPPHLSPHHPP---HLPPPGQFVPFQTQQSRSPLQRIENEVELL 265

Query: 762 MQH-PTRAHERPPP-HPHRMHPNYGHGHHIHVP--QTMSSHPRQAPERSAWELGIEAGVT 817
            +H P      PP  HP  + P+       H P  Q +S      P       G     +
Sbjct: 266 GEHLPVGGFTYPPSAHPPTLPPSAPLQFLTHDPLHQEVSFGVPYPPFMPRRLTGRSRYRS 325

Query: 818 AATYTPGALHPHLAHYHAPPRLHHLQLGALPLMVPDMAGYPHIRYISSGLDGTSFRGPFR 877
                P   HP L  Y          L  LP  VP   G P   +     DG        
Sbjct: 326 QQPIPPPPYHPSLLPY---------VLSMLP--VPPAVG-PTFSFELDVEDGEV------ 367

Query: 878 GNFEELIHLEERLGNVN-RGASQGTIERCTYPHKYKKRKLHCKQDGEEGTEEDTEEKCTI 936
            N+E L++L ERLG    RG ++  IE+      Y+               +  +  C +
Sbjct: 368 ENYEALLNLAERLGEAKPRGLTKADIEQLP---SYRFNP---------NNHQSEQTLCVV 415

Query: 937 CLSILEEGEDVRRLPCMHLFHQVCVDQWLITNKKCPICRVD 977
           C+   E  + +R LPC H FH  CVD+WL  N+ CPICR D
Sbjct: 416 CMCDFESRQLLRVLPCNHEFHAKCVDKWLKANRTCPICRAD 456


>gi|37577177 ring finger protein 38 isoform 2 [Homo sapiens]
          Length = 432

 Score = 74.7 bits (182), Expect = 4e-13
 Identities = 79/281 (28%), Positives = 106/281 (37%), Gaps = 40/281 (14%)

Query: 704 PVAPPPPTHLASTAAPIPQHLPPTHQPISHHIPATAP--PAQRLHPHEVMQRMEVQRRRM 761
           P A  PP   +      P HL P H P   H+P      P Q       +QR+E +   +
Sbjct: 176 PYAAFPPLISSDPFLIHPPHLSPHHPP---HLPPPGQFVPFQTQQSRSPLQRIENEVELL 232

Query: 762 MQH-PTRAHERPPP-HPHRMHPNYGHGHHIHVP--QTMSSHPRQAPERSAWELGIEAGVT 817
            +H P      PP  HP  + P+       H P  Q +S      P       G     +
Sbjct: 233 GEHLPVGGFTYPPSAHPPTLPPSAPLQFLTHDPLHQEVSFGVPYPPFMPRRLTGRSRYRS 292

Query: 818 AATYTPGALHPHLAHYHAPPRLHHLQLGALPLMVPDMAGYPHIRYISSGLDGTSFRGPFR 877
                P   HP L  Y          L  LP  VP   G P   +     DG        
Sbjct: 293 QQPIPPPPYHPSLLPY---------VLSMLP--VPPAVG-PTFSFELDVEDGEV------ 334

Query: 878 GNFEELIHLEERLGNVN-RGASQGTIERCTYPHKYKKRKLHCKQDGEEGTEEDTEEKCTI 936
            N+E L++L ERLG    RG ++  IE+      Y+               +  +  C +
Sbjct: 335 ENYEALLNLAERLGEAKPRGLTKADIEQLP---SYRFNP---------NNHQSEQTLCVV 382

Query: 937 CLSILEEGEDVRRLPCMHLFHQVCVDQWLITNKKCPICRVD 977
           C+   E  + +R LPC H FH  CVD+WL  N+ CPICR D
Sbjct: 383 CMCDFESRQLLRVLPCNHEFHAKCVDKWLKANRTCPICRAD 423


>gi|37577175 ring finger protein 38 isoform 1 [Homo sapiens]
          Length = 515

 Score = 74.7 bits (182), Expect = 4e-13
 Identities = 79/281 (28%), Positives = 106/281 (37%), Gaps = 40/281 (14%)

Query: 704 PVAPPPPTHLASTAAPIPQHLPPTHQPISHHIPATAP--PAQRLHPHEVMQRMEVQRRRM 761
           P A  PP   +      P HL P H P   H+P      P Q       +QR+E +   +
Sbjct: 259 PYAAFPPLISSDPFLIHPPHLSPHHPP---HLPPPGQFVPFQTQQSRSPLQRIENEVELL 315

Query: 762 MQH-PTRAHERPPP-HPHRMHPNYGHGHHIHVP--QTMSSHPRQAPERSAWELGIEAGVT 817
            +H P      PP  HP  + P+       H P  Q +S      P       G     +
Sbjct: 316 GEHLPVGGFTYPPSAHPPTLPPSAPLQFLTHDPLHQEVSFGVPYPPFMPRRLTGRSRYRS 375

Query: 818 AATYTPGALHPHLAHYHAPPRLHHLQLGALPLMVPDMAGYPHIRYISSGLDGTSFRGPFR 877
                P   HP L  Y          L  LP  VP   G P   +     DG        
Sbjct: 376 QQPIPPPPYHPSLLPY---------VLSMLP--VPPAVG-PTFSFELDVEDGEV------ 417

Query: 878 GNFEELIHLEERLGNVN-RGASQGTIERCTYPHKYKKRKLHCKQDGEEGTEEDTEEKCTI 936
            N+E L++L ERLG    RG ++  IE+      Y+               +  +  C +
Sbjct: 418 ENYEALLNLAERLGEAKPRGLTKADIEQLP---SYRFNP---------NNHQSEQTLCVV 465

Query: 937 CLSILEEGEDVRRLPCMHLFHQVCVDQWLITNKKCPICRVD 977
           C+   E  + +R LPC H FH  CVD+WL  N+ CPICR D
Sbjct: 466 CMCDFESRQLLRVLPCNHEFHAKCVDKWLKANRTCPICRAD 506


>gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
            sapiens]
          Length = 1858

 Score = 72.8 bits (177), Expect = 2e-12
 Identities = 154/719 (21%), Positives = 243/719 (33%), Gaps = 151/719 (21%)

Query: 217  VKNNSSQRTQKQKERI-LMQRKKREVLARRK---------YALLPSSSSSSENDLSSESS 266
            +  N + +   QK+++ L++ +KR+  AR+           ++ P +S S  N+   +  
Sbjct: 1142 IDGNCTPQNPPQKKKVSLLEYRKRQREARKSGSKTENFPLISVSPHASGSLSNN--GDGC 1199

Query: 267  SSSSTEGEE-------------DLFVSASENHQNNPAVPSGSIDEDVVVIEASSTPQV-- 311
            +SS+  GE+              ++ + SE   NN  V   +  E        + P+V  
Sbjct: 1200 ASSNDNGEQVDHTASLPLPTPATVYNATSEETSNNCPVKDATASE-------KNEPEVQW 1252

Query: 312  TANEEINVTSTDSEVEIVTVGESYRSRSTLGHSR------SHWSQGSSSHASRPQEPRNR 365
            TA+  +      S    + + +  + + + G S       SH     SSH++   + + +
Sbjct: 1253 TASTSVEQVRERSYQRALLLSDHRKDKDSGGESPCVSCSPSHVQSSPSSHSNHIPQLQAK 1312

Query: 366  SRISTVIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSEQASDT 425
              + +  +           L  D D     PTT+    S  TS +   S P  S+  S  
Sbjct: 1313 GPVPSFSE-----------LMEDPDPENPEPTTTNECPSPDTSQNTCKSPPKMSKPGSPG 1361

Query: 426  A--------SAVTSSQPSTVSETSATLTSNST-TGTSIGDDSRRTTSSAVTETGPPAM-- 474
            +           T   P   S  SA+   N     T +        + A+++  PP    
Sbjct: 1362 SVIPAQAHGKIFTKPDPQWDSTVSASEAENGVHLKTELQQKQLSNNNQALSKNHPPQTHV 1421

Query: 475  --------PRLPSCCPQ-HSPCGGSSQNHHALGHPHTSCFQQHGH--------HFQHHHH 517
                     +LPS   + H P     +N      PHT    QHG+             + 
Sbjct: 1422 RNSSEQLSQKLPSVPTKLHCPPSPHLENPPKSSTPHTPV--QHGYLSPKPPSQQLGSPYR 1479

Query: 518  HHHTPHPAVPVSPSFSDPACPVERPPQVQAPCGANSSSGTSYHEQQAL----PVDLSNSG 573
             HH+  P V           P   P +   P   N  + T       L    P   S++ 
Sbjct: 1480 PHHSQSPQV---------GTPQREPQRNFYPAAQNLPANTQQATSGTLFTQTPSGQSSAT 1530

Query: 574  IRSHGSGSFHGASAFDPCCPVSSSRAAIFGHQAAAAAPSQPLSSIDGYGSSMVAQPQPQP 633
                   S +  +   P  P  SS    +      +A  Q  + + G  S          
Sbjct: 1531 YSQFNQQSLNSTAPPPPPPPPPSSS---YYQNQQPSANFQNYNQLKGSLSQQTVFTSGPN 1587

Query: 634  PPQPSLSSCR----HYMPPPY--ASLTRPLHHQASACPHSHGNPPPQTQPPPQVDYVIPH 687
               P  +S +    H++ P +   S    +HHQ +A       PPP   P P      PH
Sbjct: 1588 QALPGTTSQQTVPGHHVTPGHFLPSQNPTIHHQTAAAVVP---PPPPPPPAPG-----PH 1639

Query: 688  PVHAFHSQISSHATSHPVAP----PPPTHLASTAAPIPQHLPPTHQ---PISHHIPATAP 740
             V   +S    H+ +H V P     P +H+ S  A    HLPP      P  HH P   P
Sbjct: 1640 LVQQPNSH-QQHSVAHVVGPVHAVTPGSHIHSQTA--GHHLPPPPPPPGPAPHHHP---P 1693

Query: 741  PAQRLHPHEVMQRMEVQRRRMMQHPTRAHERPPPHPHRMHPNYGHGHHIHVPQTMSSHPR 800
            P    HP   +Q ++ Q + ++         PPP P         GHH    Q +   P 
Sbjct: 1694 P----HPSTGLQGLQAQHQHVVNSAP-----PPPPPPPPSSVLASGHHTTSAQALHHPPH 1744

Query: 801  QAPERSAWELGIEAGVTAATYTPGALHPHLAHYHAPPRLHHLQLGALPLMVPDMAGYPH 859
            Q P                   P + HP +  Y +    HH  LG  P   P   G PH
Sbjct: 1745 QGP----------------PLFPSSAHPTVPPYPS-QATHHTTLGPGPQHQPSGTG-PH 1785



 Score = 38.5 bits (88), Expect = 0.031
 Identities = 43/165 (26%), Positives = 57/165 (34%), Gaps = 29/165 (17%)

Query: 472  PAMPRLPSCCPQHSPC--------GGSSQNHHALGH-------PHTSCFQQHGHHFQHHH 516
            P  P  P   P H P         G  +Q+ H +         P  S     GHH     
Sbjct: 1678 PPPPPPPGPAPHHHPPPHPSTGLQGLQAQHQHVVNSAPPPPPPPPPSSVLASGHHTTSAQ 1737

Query: 517  HHHHTPHPAVPVSPSFSDPACPVERPPQVQ-----APCGANSSSGTSYHEQQALPVDLSN 571
              HH PH   P+ PS + P  P   P Q        P   +  SGT  H     P+ ++ 
Sbjct: 1738 ALHHPPHQGPPLFPSSAHPTVP-PYPSQATHHTTLGPGPQHQPSGTGPH----CPLPVTG 1792

Query: 572  SGIRSHGSGSFHGASAFDPCCPVSSSRA---AIFGHQAAAAAPSQ 613
              ++  G  S    +A    CP   S A    + G Q A+  P Q
Sbjct: 1793 PHLQPQGPNSIPTPTA-SGFCPHPGSVALPHGVQGPQQASPVPGQ 1836


>gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
            sapiens]
          Length = 1858

 Score = 72.8 bits (177), Expect = 2e-12
 Identities = 154/719 (21%), Positives = 243/719 (33%), Gaps = 151/719 (21%)

Query: 217  VKNNSSQRTQKQKERI-LMQRKKREVLARRK---------YALLPSSSSSSENDLSSESS 266
            +  N + +   QK+++ L++ +KR+  AR+           ++ P +S S  N+   +  
Sbjct: 1142 IDGNCTPQNPPQKKKVSLLEYRKRQREARKSGSKTENFPLISVSPHASGSLSNN--GDGC 1199

Query: 267  SSSSTEGEE-------------DLFVSASENHQNNPAVPSGSIDEDVVVIEASSTPQV-- 311
            +SS+  GE+              ++ + SE   NN  V   +  E        + P+V  
Sbjct: 1200 ASSNDNGEQVDHTASLPLPTPATVYNATSEETSNNCPVKDATASE-------KNEPEVQW 1252

Query: 312  TANEEINVTSTDSEVEIVTVGESYRSRSTLGHSR------SHWSQGSSSHASRPQEPRNR 365
            TA+  +      S    + + +  + + + G S       SH     SSH++   + + +
Sbjct: 1253 TASTSVEQVRERSYQRALLLSDHRKDKDSGGESPCVSCSPSHVQSSPSSHSNHIPQLQAK 1312

Query: 366  SRISTVIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSEQASDT 425
              + +  +           L  D D     PTT+    S  TS +   S P  S+  S  
Sbjct: 1313 GPVPSFSE-----------LMEDPDPENPEPTTTNECPSPDTSQNTCKSPPKMSKPGSPG 1361

Query: 426  A--------SAVTSSQPSTVSETSATLTSNST-TGTSIGDDSRRTTSSAVTETGPPAM-- 474
            +           T   P   S  SA+   N     T +        + A+++  PP    
Sbjct: 1362 SVIPAQAHGKIFTKPDPQWDSTVSASEAENGVHLKTELQQKQLSNNNQALSKNHPPQTHV 1421

Query: 475  --------PRLPSCCPQ-HSPCGGSSQNHHALGHPHTSCFQQHGH--------HFQHHHH 517
                     +LPS   + H P     +N      PHT    QHG+             + 
Sbjct: 1422 RNSSEQLSQKLPSVPTKLHCPPSPHLENPPKSSTPHTPV--QHGYLSPKPPSQQLGSPYR 1479

Query: 518  HHHTPHPAVPVSPSFSDPACPVERPPQVQAPCGANSSSGTSYHEQQAL----PVDLSNSG 573
             HH+  P V           P   P +   P   N  + T       L    P   S++ 
Sbjct: 1480 PHHSQSPQV---------GTPQREPQRNFYPAAQNLPANTQQATSGTLFTQTPSGQSSAT 1530

Query: 574  IRSHGSGSFHGASAFDPCCPVSSSRAAIFGHQAAAAAPSQPLSSIDGYGSSMVAQPQPQP 633
                   S +  +   P  P  SS    +      +A  Q  + + G  S          
Sbjct: 1531 YSQFNQQSLNSTAPPPPPPPPPSSS---YYQNQQPSANFQNYNQLKGSLSQQTVFTSGPN 1587

Query: 634  PPQPSLSSCR----HYMPPPY--ASLTRPLHHQASACPHSHGNPPPQTQPPPQVDYVIPH 687
               P  +S +    H++ P +   S    +HHQ +A       PPP   P P      PH
Sbjct: 1588 QALPGTTSQQTVPGHHVTPGHFLPSQNPTIHHQTAAAVVP---PPPPPPPAPG-----PH 1639

Query: 688  PVHAFHSQISSHATSHPVAP----PPPTHLASTAAPIPQHLPPTHQ---PISHHIPATAP 740
             V   +S    H+ +H V P     P +H+ S  A    HLPP      P  HH P   P
Sbjct: 1640 LVQQPNSH-QQHSVAHVVGPVHAVTPGSHIHSQTA--GHHLPPPPPPPGPAPHHHP---P 1693

Query: 741  PAQRLHPHEVMQRMEVQRRRMMQHPTRAHERPPPHPHRMHPNYGHGHHIHVPQTMSSHPR 800
            P    HP   +Q ++ Q + ++         PPP P         GHH    Q +   P 
Sbjct: 1694 P----HPSTGLQGLQAQHQHVVNSAP-----PPPPPPPPSSVLASGHHTTSAQALHHPPH 1744

Query: 801  QAPERSAWELGIEAGVTAATYTPGALHPHLAHYHAPPRLHHLQLGALPLMVPDMAGYPH 859
            Q P                   P + HP +  Y +    HH  LG  P   P   G PH
Sbjct: 1745 QGP----------------PLFPSSAHPTVPPYPS-QATHHTTLGPGPQHQPSGTG-PH 1785



 Score = 38.5 bits (88), Expect = 0.031
 Identities = 43/165 (26%), Positives = 57/165 (34%), Gaps = 29/165 (17%)

Query: 472  PAMPRLPSCCPQHSPC--------GGSSQNHHALGH-------PHTSCFQQHGHHFQHHH 516
            P  P  P   P H P         G  +Q+ H +         P  S     GHH     
Sbjct: 1678 PPPPPPPGPAPHHHPPPHPSTGLQGLQAQHQHVVNSAPPPPPPPPPSSVLASGHHTTSAQ 1737

Query: 517  HHHHTPHPAVPVSPSFSDPACPVERPPQVQ-----APCGANSSSGTSYHEQQALPVDLSN 571
              HH PH   P+ PS + P  P   P Q        P   +  SGT  H     P+ ++ 
Sbjct: 1738 ALHHPPHQGPPLFPSSAHPTVP-PYPSQATHHTTLGPGPQHQPSGTGPH----CPLPVTG 1792

Query: 572  SGIRSHGSGSFHGASAFDPCCPVSSSRA---AIFGHQAAAAAPSQ 613
              ++  G  S    +A    CP   S A    + G Q A+  P Q
Sbjct: 1793 PHLQPQGPNSIPTPTA-SGFCPHPGSVALPHGVQGPQQASPVPGQ 1836


>gi|7662486 ring finger protein 44 [Homo sapiens]
          Length = 432

 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 91/324 (28%), Positives = 126/324 (38%), Gaps = 59/324 (18%)

Query: 677 PPPQVDYV----IPHPVHAFHSQISS-HATSHPVAPPPPTHLASTAAPIPQHLPPTHQPI 731
           PPP +       +P P  A+   ISS H   HP  P PP        P P H+ P  Q +
Sbjct: 153 PPPLIQACTMQQLPVPYQAYPHLISSDHYILHPPPPAPP--------PQPTHMAPLGQFV 204

Query: 732 SHHIPATAPPAQRLHPHEVMQRMEVQRRRMMQHPTRA-----HERPPPH--PHR-MHPNY 783
           S        P QRL  ++V  R +        + T A         P H  PH  +H   
Sbjct: 205 SLQTQHPRMPLQRLD-NDVDLRGDQPSLGSFTYSTSAPGPALSPSVPLHYLPHDPLHQEL 263

Query: 784 GHGHHIHVPQTMSSHPRQAPERSAWELGIEAGVTAATYTPGALHPHLAHYHAPPRLHHLQ 843
             G    VP +     R + +R  + L            P   +P    Y          
Sbjct: 264 SFG----VPYSHMMPRRLSTQR--YRLQQPLPPPPPPPPPPPYYPSFLPYF--------- 308

Query: 844 LGALPLMVPDMAGYPHIRYISSGLDGTSFRGPFRGNFEELIHLEERLGNVN-RGASQGTI 902
           L  LP M P   G      IS  LD          N+E L++L ERLG+   RG ++  I
Sbjct: 309 LSMLP-MSPTAMGPT----ISLDLDVDDVE---MENYEALLNLAERLGDAKPRGLTKADI 360

Query: 903 ERCTYPHKYKKRKLHCKQDGEEGTEEDTEEKCTICLSILEEGEDVRRLPCMHLFHQVCVD 962
           E+      Y+             + +  +  C +C S  E  + +R LPC H FH  CVD
Sbjct: 361 EQLP---SYRFNP---------DSHQSEQTLCVVCFSDFEARQLLRVLPCNHEFHTKCVD 408

Query: 963 QWLITNKKCPICRVDIEAQLPSES 986
           +WL  N+ CPICR D  +++P E+
Sbjct: 409 KWLKANRTCPICRAD-ASEVPREA 431



 Score = 37.4 bits (85), Expect = 0.070
 Identities = 43/169 (25%), Positives = 63/169 (37%), Gaps = 47/169 (27%)

Query: 635 PQPSLSSCR-HYMPPPYASLTRPLHHQASACPHSHGNPPPQTQPPPQVDYVIPHPVHAFH 693
           P P + +C    +P PY +    +     +  H   +PPP   PPPQ  ++ P       
Sbjct: 153 PPPLIQACTMQQLPVPYQAYPHLI-----SSDHYILHPPPPA-PPPQPTHMAPL------ 200

Query: 694 SQISSHATSHPVAPPPP---------------THLASTAAPIP--------QHLP--PTH 728
            Q  S  T HP  P                  +   ST+AP P         +LP  P H
Sbjct: 201 GQFVSLQTQHPRMPLQRLDNDVDLRGDQPSLGSFTYSTSAPGPALSPSVPLHYLPHDPLH 260

Query: 729 QPISHHIPATAPPAQRLHPHEVMQRMEVQRRRMMQHPTRAHERPPPHPH 777
           Q +S  +P         + H + +R+  QR R+ Q        PPP P+
Sbjct: 261 QELSFGVP---------YSHMMPRRLSTQRYRLQQPLPPPPPPPPPPPY 300



 Score = 30.4 bits (67), Expect = 8.5
 Identities = 35/156 (22%), Positives = 51/156 (32%), Gaps = 34/156 (21%)

Query: 505 FQQHGHHFQHHHHHHHTPHPAVPVSPSFSDPACPVERPPQVQAPCGANSSSGTSYHEQQA 564
           +Q + H     H+  H P PA P  P+               AP G   S  T +     
Sbjct: 169 YQAYPHLISSDHYILHPPPPAPPPQPTH-------------MAPLGQFVSLQTQHPR--- 212

Query: 565 LPVDLSNSGIRSHGSGSFHGASAFDPCCPVSSSRAAIFGHQAAAAAPSQPLSSIDGYGSS 624
           +P+   ++ +   G     G+  +    P  +   ++  H        Q LS    Y   
Sbjct: 213 MPLQRLDNDVDLRGDQPSLGSFTYSTSAPGPALSPSVPLHYLPHDPLHQELSFGVPYSHM 272

Query: 625 M----------VAQPQPQPPPQPSLSSCRHYMPPPY 650
           M          + QP P PPP P         PPPY
Sbjct: 273 MPRRLSTQRYRLQQPLPPPPPPPP--------PPPY 300


>gi|29789407 ring finger protein 149 [Homo sapiens]
          Length = 400

 Score = 68.6 bits (166), Expect = 3e-11
 Identities = 24/63 (38%), Positives = 43/63 (68%), Gaps = 1/63 (1%)

Query: 916 LHCKQDGEEGTEEDTEEKCTICLSILEEGEDVRRLPCMHLFHQVCVDQWLITNKKCPICR 975
           LH  + GE+G + D E  C +C+   +  + +R LPC H+FH++C+D WL+ ++ CP+C+
Sbjct: 252 LHTVKHGEKGIDVDAEN-CAVCIENFKVKDIIRILPCKHIFHRICIDPWLLDHRTCPMCK 310

Query: 976 VDI 978
           +D+
Sbjct: 311 LDV 313


>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
            sapiens]
          Length = 1362

 Score = 67.8 bits (164), Expect = 5e-11
 Identities = 165/740 (22%), Positives = 251/740 (33%), Gaps = 149/740 (20%)

Query: 139  SSPSSSLHFGDSDTVTSDEDKEVSVR-----------HSQTILNAKSRSHSARSHKWPRT 187
            SS SSS    DSD+ T D ++E + R           H Q    ++ + +  +  +  + 
Sbjct: 485  SSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKK 544

Query: 188  ETESVSGLLMKRPCLHGSSLRRLPCRKRFVKNNSSQRTQKQKERILMQRK---------- 237
            E +       +    +  S  + P  K+  KNNSS     +KE   M+ K          
Sbjct: 545  EKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEE 604

Query: 238  ----------KREV-----------LARRKYALL---PSSSSSSENDLSSESSS-SSSTE 272
                      KR++           L R  + +    PS  +S+ +++  +  +   ST 
Sbjct: 605  DKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTL 664

Query: 273  GEEDLFVSASENHQNNPAVPSGSIDEDVVVIEA-SSTPQVTANEEINVTSTDSEVEIVTV 331
             E + +V++    +  P      +      ++  SS+   +++E  +  S DSE E+   
Sbjct: 665  RELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPK 724

Query: 332  GES--YRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSRISTVIQPLRQNAAEVVDLTVDE 389
             +   +  R    H   H  Q   + A  PQ+P    +      P +Q           +
Sbjct: 725  SKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQ-----------Q 773

Query: 390  DEPTVVPTTSARMESQATSASINNSNPSTSEQASDTASAVTSSQPSTVSETSATLTSNST 449
             +P   P                   PS  +QA   A A+ SS P  ++ T   +     
Sbjct: 774  QQPPPPPPP-----------------PSMPQQA---APAMKSSPPPFIA-TQVPVLEPQL 812

Query: 450  TGTSIGDDSRRTTSSAVTETGPPAMPRLPSCCPQHSPCGGSSQNHHALGHP---HTSCFQ 506
             G S+ D     T   +    P   P LP   P+HS       N HA+  P   H +  Q
Sbjct: 813  PG-SVFDPIGHFTQPILHLPQPELPPHLPQP-PEHST--PPHLNQHAVVSPPALHNALPQ 868

Query: 507  QHGHHFQHHHHHHHTPHPAVP--VSPSFSD----PACPVERPPQVQAPCGANSSSGTSYH 560
            Q       +      P PA P  VSP+ +     P  P+ +PPQV               
Sbjct: 869  QPSR--PSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLL----------EDE 916

Query: 561  EQQALPVDLSNSGIRSHGSGSFHGASAFDPCCPVSSSRAAIFGHQAAAAAPSQPLSSIDG 620
            E  A P+      +           +   P   V S        Q     P  P  S+  
Sbjct: 917  EPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQS--------QPPPPLPPPPHPSVQ- 967

Query: 621  YGSSMVAQPQPQPPPQPSLSSCRHYMPPPYASLTRPLHHQ-ASACPHSHGNPPPQTQPPP 679
                +  QP P PPPQP     + + PPP     RP+H Q      H    PPPQ Q PP
Sbjct: 968  --QQLQQQPPPPPPPQPQPPPQQQHQPPP-----RPVHLQPMQFSTHIQQPPPPQGQQPP 1020

Query: 680  Q--VDYVIPHPVHAFHSQISSHATS---HPVAPPPPTHLASTAAPIPQHLP--PTHQPIS 732
                    P P  A   Q+  H  S   H   P    HL    +P+  H P     Q ++
Sbjct: 1021 HPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLT 1080

Query: 733  HHIPA---TAPPAQRLHPHEVM--QRMEVQRRRMMQHPTRAHE--------RPPPHPHRM 779
            H  P      P  Q L    V+  Q + V +   +  P    E         PP HP  +
Sbjct: 1081 HQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESI 1140

Query: 780  HPNYGHGHHIHVPQTMSSHP 799
                     +H+PQ     P
Sbjct: 1141 KA------PVHLPQRPEMKP 1154



 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 111/515 (21%), Positives = 165/515 (32%), Gaps = 120/515 (23%)

Query: 387  VDEDEPTVVPTTSARMESQATSASINNSNPSTSEQASDTASAVTSSQPSTVSETSATLTS 446
            ++ D  T+ P+T   +E   TS       P   +      S+      S+ SE+S     
Sbjct: 652  IEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESS----- 706

Query: 447  NSTTGTSIGDDSRRTTSSAVTETGPPAMPRLPSCCPQHSPCGGSSQNHHALGHPHTSCFQ 506
             S + +S  +DS        TE  P +  +                     GHP      
Sbjct: 707  -SESSSSDSEDSE-------TEMAPKSKKK---------------------GHP------ 731

Query: 507  QHGHHFQHHHHHHHTPHPAVPVSPSFSDPACPVERPPQVQAPCGANSSSGTSYHEQQALP 566
              G   + HHHHHH      P +P    P  P ++PP    P            +QQ  P
Sbjct: 732  --GREQKKHHHHHHQQMQQAP-APVPQQPPPPPQQPPPPPPP-----------QQQQQPP 777

Query: 567  VDLSNSGIRSHGSGSFHGASAFDPCCPVSSSRAAIFGHQAAAAAPSQPLSSIDGYG---S 623
                   +    + +            + SS       Q     P  P S  D  G    
Sbjct: 778  PPPPPPSMPQQAAPA------------MKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQ 825

Query: 624  SMVAQPQPQPPP---QPSLSSCRHYMPP---PYASLTRPLHHQASACPHSHGNP------ 671
             ++  PQP+ PP   QP      H  PP    +A ++ P  H  +A P     P      
Sbjct: 826  PILHLPQPELPPHLPQPP----EHSTPPHLNQHAVVSPPALH--NALPQQPSRPSNRAAA 879

Query: 672  -PPQTQPPPQVDY------VIPHPVHAFHSQISSHATSHPVAPPPPTHLASTAAPIPQHL 724
             PP+   PP V        ++P P  A   Q+       P  P     +      + +  
Sbjct: 880  LPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQ 939

Query: 725  PPTHQPISHHIPATAPPAQRLHPHEVMQRMEVQRRR-----MMQHPTRAHERPPPHPHRM 779
            PPT    S  + +  PP     PH  +Q+   Q+         Q P +   +PPP P  +
Sbjct: 940  PPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHL 999

Query: 780  HPNYGHGHHIHVPQTMSSHPRQAPERSAWELGIEAGVTAATYTPGALHPHLAHYHAPPRL 839
             P     H    P      P   P           G       P      + H+H+ PR 
Sbjct: 1000 QPMQFSTHIQQPPPPQGQQPPHPP----------PGQQPPPPQPAKPQQVIQHHHS-PRH 1048

Query: 840  H--------HLQLGALPLMV--PDMAGYPHIRYIS 864
            H        HL+    PLM+  P M+ +  + + S
Sbjct: 1049 HKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQS 1083



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 37/119 (31%), Positives = 44/119 (36%), Gaps = 14/119 (11%)

Query: 667 SHGNPPPQTQPP---PQVDYVIPHPVHAFHSQISSHATSHPVAPPPPTHLASTAAPIPQH 723
           +  + PPQTQ P   P      PHP  A    +        V PP P        P PQ 
Sbjct: 200 TQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQP 259

Query: 724 LP-PTHQPISHHIPATAPPAQRLHPHEVMQRMEVQRRRMMQHPTR---AHERP--PPHP 776
            P P  QP+  H     PP     P  V  +  V+R+     PT     HE P  PP P
Sbjct: 260 PPAPAPQPVQSH-----PPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEP 313



 Score = 33.5 bits (75), Expect = 1.0
 Identities = 25/94 (26%), Positives = 37/94 (39%), Gaps = 3/94 (3%)

Query: 629 PQPQPPPQPSLSSCRHYMPPPYASLTRPLHHQASACPHSHGNPPPQTQPPPQVDYVIPHP 688
           PQPQPPP P+    + + PP  A+  +P+  +      +    P    P  +   + P P
Sbjct: 255 PQPQPPPAPAPQPVQSH-PPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEP 313

Query: 689 VHAFHSQISSHATSHPVAPPPPTHLASTAAPIPQ 722
                 Q     +S PV PP      S   P P+
Sbjct: 314 KTTKLGQ--RRESSRPVKPPKKDVPDSQQHPAPE 345



 Score = 33.5 bits (75), Expect = 1.0
 Identities = 45/211 (21%), Positives = 86/211 (40%), Gaps = 34/211 (16%)

Query: 72  QKQEKEMNGNQQEQEKSLVVRKKRKSQQAGPSYVQNCVKENQGILGLRQHLGTPSDEDND 131
           +K +KE    + ++++ +   KK K+++  P   +                       N+
Sbjct: 540 EKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKK----------------------NN 577

Query: 132 SSFSDCLSSPSSSLHFGDSDTVTSDEDKEVSVRHSQTILNAKSRSHSARSHKWPRTETES 191
           SS S+      + +      T  S+E+ +      +     + R  S   +K P  +   
Sbjct: 578 SSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYE-----EKRQLSLDINKLPGEKLGR 632

Query: 192 VSGLLMKR-PCLHGSSLRRLPCRKRFVKNNSSQRTQKQKERILMQRKKREVLARRKYALL 250
           V  ++  R P L  S+   +      +K ++ +  ++     L  RKKR+  A +   + 
Sbjct: 633 VVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCL--RKKRKPQAEKVDVIA 690

Query: 251 PSSS----SSSENDLSSESSSSSSTEGEEDL 277
            SS     SSSE++ SSESSSS S + E ++
Sbjct: 691 GSSKMKGFSSSESESSSESSSSDSEDSETEM 721


>gi|151301053 RNA binding motif protein 33 [Homo sapiens]
          Length = 1170

 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 91/375 (24%), Positives = 124/375 (33%), Gaps = 53/375 (14%)

Query: 454 IGDDSRRTTSSAVTETGPPAM-PRLPSCCPQHSPCGGSSQNHHALGHPHTSCFQQHGHH- 511
           +GD  R +T     +   PA+ P  P   PQ  P             P  S FQ      
Sbjct: 288 VGDQRRESTERGRMKDHRPALLPTQPPVVPQAPPPPPPPPQQQ----PIRSLFQPQPLQP 343

Query: 512 -FQHHHHHHHTPHPAVPVSPSFSDPACPVERPPQV-QAPCGANSS---SGTSYHEQQALP 566
                H HH +P   + + P    P   +  PP   Q P   + +    GT     Q   
Sbjct: 344 LLPVQHPHHPSPPQGMHMPPQLETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPL 403

Query: 567 VDLSNSGIRSHGSGSFHGASAFDP----CCPVSSSRAAIFGHQAAAAAPSQPLSSIDGYG 622
           + + +    + G   F G   F        P S S+      Q    AP  P    D + 
Sbjct: 404 LPVPSQPRPAVGPQRFPGPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPP-QDRDPFF 462

Query: 623 SSMVAQPQ------------PQPPPQPSLSSCRHYMPPPYASLTRPLHHQASACPHSHGN 670
             +  +P+            P PPP P+L +  H +P        P      A       
Sbjct: 463 LGVSGEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVP---TQSPLPFTQPGPAFNQQGQQ 519

Query: 671 PPPQTQPPPQVDYVIPHPVHAFHSQISSHATSHPVAPPP------------PTHL-ASTA 717
           P    + P +     P PV   H      AT+ P  PP             PTH   +  
Sbjct: 520 PVFPRERPVRPALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQ 579

Query: 718 APIPQHLPPTHQPISHHIPATAPPAQRLHPHEVMQRMEVQRRRMMQHPTRAHERPPPHPH 777
            P+   LPP HQP     P   PP Q   PH+   +   Q +   QHP    + PP H H
Sbjct: 580 GPLHPPLPPPHQPQPQQ-PQQQPPPQHQPPHQPPHQPPPQHQPPPQHPP---QHPPQHQH 635

Query: 778 RMHPNYGHGHHIHVP 792
                + H HH+ VP
Sbjct: 636 -----HHHHHHLSVP 645



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 69/299 (23%), Positives = 92/299 (30%), Gaps = 64/299 (21%)

Query: 512 FQHHHHHHHTPHPAVPVSPSFSDPACPVERPPQVQAPCGANSSSGTSYHEQQALPVDLSN 571
           F  H        P  P  P+  + + PV  P Q   P    +  G ++++Q   PV    
Sbjct: 471 FPSHLFLEQRSPPPPPPPPTLLNSSHPV--PTQSPLPF---TQPGPAFNQQGQQPVFPRE 525

Query: 572 SGIRSHGSGSFHGASAFDPCCPV----------SSSRAAIFGHQAAAAAPSQPLSSIDGY 621
             +R           A  P  PV          +++R  I   Q     P QP       
Sbjct: 526 RPVRP----------ALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTH-- 573

Query: 622 GSSMVAQPQPQPPPQPSLSSCRHYMPPPYASLTRPLHHQASACPHSHGNPP--PQTQPPP 679
                 QP  Q P  P L       PPP+    +P   Q    P     PP  P  QPPP
Sbjct: 574 -----TQPNLQGPLHPPL-------PPPH----QPQPQQPQQQPPPQHQPPHQPPHQPPP 617

Query: 680 QVDYVIPHPVHAFHSQISSHATSHPVAPPPPTHLASTAAPIPQHLPPTHQPISHHIPATA 739
           Q      HP          H   H   PPPP             L P  Q      P   
Sbjct: 618 QHQPPPQHPPQHPPQHQHHHHHHHLSVPPPP-------------LMPMSQ------PQFR 658

Query: 740 PPAQRLHPHEVMQRMEVQRRRMMQHPTRAHERPPPHPHRMHPNYGHGHHIHVPQTMSSH 798
           P  Q   P     RM+  +R+ ++H T +         +M P      ++       SH
Sbjct: 659 PHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPRNSNLRELPIAPSH 717



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 44/171 (25%), Positives = 57/171 (33%), Gaps = 20/171 (11%)

Query: 482 PQHSPCGGSSQNHHALGHPHTSCFQQHGHHFQHHHHHHH---TPHPAVPVSPSFSDPACP 538
           PQH P             P      QH    QHHHHHHH    P P +P+S     P   
Sbjct: 603 PQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVPPPPLMPMSQPQFRPHVQ 662

Query: 539 VERP---------PQVQAPCGANSSSGTSYHE-QQALPVDLSNSGIRSHGSGSFHGASAF 588
             +P         PQ Q      +S   S    QQ  P    NS +R       H     
Sbjct: 663 TAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPRNSNLRELPIAPSHVIEMS 722

Query: 589 DPCCPVSSS-------RAAIFGHQAAAAAPSQPLSSIDGYGSSMVAQPQPQ 632
              C  + S        A+      A +  SQ  + +    +S VAQP+ +
Sbjct: 723 SSRCSATPSAQVKPIVSASPPSRAVAGSRSSQGKTEVKVKPASPVAQPKEE 773


>gi|237757312 synaptojanin 1 isoform c [Homo sapiens]
          Length = 1295

 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 94/370 (25%), Positives = 140/370 (37%), Gaps = 51/370 (13%)

Query: 369  STVIQPLRQNAAEVVD--LTVDEDEPTVVPTTSARMESQATSASINNSNPSTSEQASDTA 426
            S+ +  L  N  E+++  +T+    P  +      M  +  S ++ +S  ST     D  
Sbjct: 946  SSALNVLSLNGKELLNRTITIALKSPDWIKNLEEEMSLEKISIALPSSTSSTL-LGEDAE 1004

Query: 427  SAVTSSQPSTVSETSATL----------TSNSTTGTSIGDDSRRTT--SSAVTETGPPAM 474
             A        V + SA +          +S+S  GTS     R +   S  ++E   P++
Sbjct: 1005 VAADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSL 1064

Query: 475  PRLPSCCPQHSPCGGSSQNHHALGHPHTSCFQQHGHHFQHHHHHHHTPHPAVPVSPSFSD 534
            P  PS  P  +P   S+Q+      P T   Q+              P P  PV+P  + 
Sbjct: 1065 PIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKD----PAQPLEPKRPPPPRPVAPP-TR 1119

Query: 535  PACPVERPPQ--VQAPC------GANSSSGTSYHEQQALPVDLSNSGIRSHGSGSFHGAS 586
            PA P   PP    ++P       GA  S GT+  +          +G+   G   +  A 
Sbjct: 1120 PAPPQRPPPPSGARSPAPTRKEFGAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTAR 1179

Query: 587  AFDPCCPVSSSRAAIFGHQAAAAA----PSQPLSSIDGYGSSMVAQP-QPQP--PPQPSL 639
               P  P +   +A   H  A+A      SQ  +S    GS+ + +P +PQ   PPQ SL
Sbjct: 1180 PTIP--PRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSL 1237

Query: 640  SSCRHYMPPPYASLTRPLHHQASACPHSHGNPPPQTQPPPQVDYVIPHPVHAFHSQISSH 699
                   PPP   L  PL   A+  P S   P P  + PPQ     P P       + S 
Sbjct: 1238 -------PPPAQRLQEPLVPVAAPMPQS--GPQPNLETPPQ-----PPPRSRSSHSLPSE 1283

Query: 700  ATSHPVAPPP 709
            A+S P    P
Sbjct: 1284 ASSQPQQEQP 1293



 Score = 34.7 bits (78), Expect = 0.45
 Identities = 32/112 (28%), Positives = 38/112 (33%), Gaps = 18/112 (16%)

Query: 616  SSIDGYGSSMVAQPQPQPPPQPSLSSCRHYMPPPYASLT-RPLHHQASACPHSHGNPPPQ 674
            SS  G G+S  + P+  P   P++S        P  SL  RP     S  P     PP  
Sbjct: 1033 SSSSGLGTSPSSSPRTSPCQSPTISE------GPVPSLPIRP-----SRAPSRTPGPPSA 1081

Query: 675  TQPPPQVDYVIPHPVHAFHSQISSHATSHPVAPPPPTHLASTAAPIPQHLPP 726
               P       P P      Q        P  PPPP  +A    P P   PP
Sbjct: 1082 QSSPIDAQPATPLP------QKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPP 1127


>gi|58331204 ring finger protein 150 [Homo sapiens]
          Length = 438

 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 25/66 (37%), Positives = 43/66 (65%), Gaps = 1/66 (1%)

Query: 913 KRKLHCKQDGEEGTEEDTEEKCTICLSILEEGEDVRRLPCMHLFHQVCVDQWLITNKKCP 972
           K ++   + G++ TE D +  C +C+   +  + VR LPC HLFH+ CVD WL+ ++ CP
Sbjct: 258 KLQIRTIKKGDKETESDFDN-CAVCIEGYKPNDVVRILPCRHLFHKSCVDPWLLDHRTCP 316

Query: 973 ICRVDI 978
           +C+++I
Sbjct: 317 MCKMNI 322


>gi|34452686 ring finger protein, LIM domain interacting [Homo
           sapiens]
          Length = 624

 Score = 61.2 bits (147), Expect = 5e-09
 Identities = 25/60 (41%), Positives = 36/60 (60%)

Query: 927 EEDTEEKCTICLSILEEGEDVRRLPCMHLFHQVCVDQWLITNKKCPICRVDIEAQLPSES 986
           E D  + C++C++   EG  +R+LPC H +H  C+D+WL  N  CPICR  + A    ES
Sbjct: 563 ENDALKTCSVCITEYTEGNKLRKLPCSHEYHVHCIDRWLSENSTCPICRRAVLASGNRES 622



 Score = 39.7 bits (91), Expect = 0.014
 Identities = 85/393 (21%), Positives = 152/393 (38%), Gaps = 91/393 (23%)

Query: 127 DEDNDSSFSDCLSSPSSSLHFGDSDTVTSDEDKEVSVRHSQTILNAKSRSHSARSHKWPR 186
           + +N S  S+  + PS+    G++  V ++  ++V         N +S S SAR  +  R
Sbjct: 144 NRNNGSQNSENENEPSARRSSGEN--VENNSQRQVE--------NPRSESTSARPSRSER 193

Query: 187 TETESVSGLLMKRPCLHGSSLRRLPCRKRFVKNNSSQRTQKQKERILMQRKKREVLARRK 246
             TE+++ +    P   G        R+   ++   +RT+ + ER          + RR 
Sbjct: 194 NSTEALTEV----PPTRGQ-------RRARSRSPDHRRTRARAERSRSPLHPMSEIPRRS 242

Query: 247 YALLPSSSSSSENDLSSESSSSSSTEGEEDLFVSAS-----------ENHQNNPAVPSGS 295
           +  +  SS + E+ L +E+  SS T     L    S            +   N +  +GS
Sbjct: 243 HHSI--SSQTFEHPLVNETEGSSRTRHHVTLRQQISGPELLSRGLFAASGTRNASQGAGS 300

Query: 296 IDEDVVVIEASSTPQVTANEEINVTSTDSEVEIVTVGESYRSRSTLG---HSRSHWSQGS 352
            D       A+S     + +       D +V  V  GE YR R ++     SRS     +
Sbjct: 301 SDT------AASGESTGSGQRPPTIVLDLQVRRVRPGE-YRQRDSIASRTRSRSQTPNNT 353

Query: 353 SSHAS----------RPQEPRNRSRISTVIQPLRQ----NAAEVVDLTVD---------- 388
            ++ S          R +    R+ +ST+  P+R+      +E   + +           
Sbjct: 354 VTYESERGGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGF 413

Query: 389 -----------EDEPT--VVPTTSARMESQA----------TSASINNSNPSTSEQASDT 425
                      + EPT  V      R ES++          + +S ++S+ S+S  +S +
Sbjct: 414 GELSYFMYSDSDSEPTGSVSNRNMERAESRSGRGGSGGGSSSGSSSSSSSSSSSSSSSSS 473

Query: 426 ASAVTSSQPSTVSETSATLTSNSTTGTSIGDDS 458
           +S+ +SS     SETS+ L   S  G+S    S
Sbjct: 474 SSSPSSSSGGESSETSSDLFEGSNEGSSSSGSS 506


>gi|34452684 ring finger protein, LIM domain interacting [Homo
           sapiens]
          Length = 624

 Score = 61.2 bits (147), Expect = 5e-09
 Identities = 25/60 (41%), Positives = 36/60 (60%)

Query: 927 EEDTEEKCTICLSILEEGEDVRRLPCMHLFHQVCVDQWLITNKKCPICRVDIEAQLPSES 986
           E D  + C++C++   EG  +R+LPC H +H  C+D+WL  N  CPICR  + A    ES
Sbjct: 563 ENDALKTCSVCITEYTEGNKLRKLPCSHEYHVHCIDRWLSENSTCPICRRAVLASGNRES 622



 Score = 39.7 bits (91), Expect = 0.014
 Identities = 85/393 (21%), Positives = 152/393 (38%), Gaps = 91/393 (23%)

Query: 127 DEDNDSSFSDCLSSPSSSLHFGDSDTVTSDEDKEVSVRHSQTILNAKSRSHSARSHKWPR 186
           + +N S  S+  + PS+    G++  V ++  ++V         N +S S SAR  +  R
Sbjct: 144 NRNNGSQNSENENEPSARRSSGEN--VENNSQRQVE--------NPRSESTSARPSRSER 193

Query: 187 TETESVSGLLMKRPCLHGSSLRRLPCRKRFVKNNSSQRTQKQKERILMQRKKREVLARRK 246
             TE+++ +    P   G        R+   ++   +RT+ + ER          + RR 
Sbjct: 194 NSTEALTEV----PPTRGQ-------RRARSRSPDHRRTRARAERSRSPLHPMSEIPRRS 242

Query: 247 YALLPSSSSSSENDLSSESSSSSSTEGEEDLFVSAS-----------ENHQNNPAVPSGS 295
           +  +  SS + E+ L +E+  SS T     L    S            +   N +  +GS
Sbjct: 243 HHSI--SSQTFEHPLVNETEGSSRTRHHVTLRQQISGPELLSRGLFAASGTRNASQGAGS 300

Query: 296 IDEDVVVIEASSTPQVTANEEINVTSTDSEVEIVTVGESYRSRSTLG---HSRSHWSQGS 352
            D       A+S     + +       D +V  V  GE YR R ++     SRS     +
Sbjct: 301 SDT------AASGESTGSGQRPPTIVLDLQVRRVRPGE-YRQRDSIASRTRSRSQTPNNT 353

Query: 353 SSHAS----------RPQEPRNRSRISTVIQPLRQ----NAAEVVDLTVD---------- 388
            ++ S          R +    R+ +ST+  P+R+      +E   + +           
Sbjct: 354 VTYESERGGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGF 413

Query: 389 -----------EDEPT--VVPTTSARMESQA----------TSASINNSNPSTSEQASDT 425
                      + EPT  V      R ES++          + +S ++S+ S+S  +S +
Sbjct: 414 GELSYFMYSDSDSEPTGSVSNRNMERAESRSGRGGSGGGSSSGSSSSSSSSSSSSSSSSS 473

Query: 426 ASAVTSSQPSTVSETSATLTSNSTTGTSIGDDS 458
           +S+ +SS     SETS+ L   S  G+S    S
Sbjct: 474 SSSPSSSSGGESSETSSDLFEGSNEGSSSSGSS 506


>gi|55750053 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 61.2 bits (147), Expect = 5e-09
 Identities = 118/513 (23%), Positives = 165/513 (32%), Gaps = 84/513 (16%)

Query: 349 SQGSSSHASRPQEPRNRSRISTVIQPLRQNAAEVVDLTVDEDEPTVVPT-TSARME---- 403
           +  S   A + ++   ++R+     P         +++  E E T  P  T    E    
Sbjct: 40  TSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRP 99

Query: 404 ---SQATSASINNSNPSTSEQASDTASAVTSSQPSTVSETSATLTSNSTTGTSIGDDSRR 460
              S   S    + N   S    D      S+ PS  S  S    S+S++G S G     
Sbjct: 100 QSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGP---- 155

Query: 461 TTSSAVTETGPPAMPRLPSCCPQHSPCGGSSQNHHALGHPHTSCFQQHGHHFQHH---HH 517
               A     PP  P      P   P   + +   A   PH S     G+H         
Sbjct: 156 ----ARPYHPPPLFP------PSPQPPDSTPRQPEASFEPHPSVTPT-GYHAPMEPPTSR 204

Query: 518 HHHTPHPAVPVSPSF--SDPACPVERPPQVQAPCGANSS----SGTSYHEQQALPVDLSN 571
               P  A P  P          +  PP      GA SS    +G   H     P+ +S+
Sbjct: 205 MFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSS 264

Query: 572 SGIRSH----------GSGSFHGA---SAFDPCCPVSSSRAAIFGHQAAAAAP----SQP 614
           SG              G G+   A   + F    P      A+     A+A+P    +QP
Sbjct: 265 SGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQP 324

Query: 615 LS----SIDGYGSSMVAQPQPQPPPQPSLSSCRHYMPPPYASLTRP-------LHHQASA 663
           L     S    G  M   P P P   P+L+   H +PP  +S   P           +SA
Sbjct: 325 LPGHLPSPHAMGQGMGGLP-PGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSA 383

Query: 664 CPHSHGNPPPQTQPPPQVDYVIPHPVHAFHSQISSHATSHPV---------------APP 708
              S  +    +  P      +P   H+F    S   ++ P                 PP
Sbjct: 384 AASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPP 443

Query: 709 PPTHLASTAAPIPQHLPPTHQPISHHIPATA-PPAQRLHPHEVMQRMEVQRRRMMQHPTR 767
           PP       A    H  P   P S    +TA PP    H H   Q+ + Q+++  Q   +
Sbjct: 444 PPPPYGRLLANSNAH--PGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQ 501

Query: 768 AH---ERPPPHPHRMHP-NYGHGHHIHVPQTMS 796
            H     PPP     HP   G  HH H P  MS
Sbjct: 502 QHHGNSGPPPPGAFPHPLEGGSSHHAH-PYAMS 533



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 59/232 (25%), Positives = 79/232 (34%), Gaps = 45/232 (19%)

Query: 524 PAVPVSPSFSDPACPVERPPQVQAPCGANSSSGTSYHEQQALPVDLSNSGIRSHGSGSFH 583
           P +  SP    PA      P ++ P  ++SSS  +           S+S   S  S S  
Sbjct: 350 PTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAA----------ASSSSSSSSSSASPF 399

Query: 584 GASAFDPCCPVS---SSRAAIFGHQAAAAAPSQPLSSIDGYG-------SSMVAQPQPQP 633
            AS   P  P S    +  ++         PS P  ++   G         ++A     P
Sbjct: 400 PASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHP 459

Query: 634 PPQPSLSSCRHYMPPPYASLTRPLHHQASACPHS------------HGNPPPQTQPPPQV 681
            P P  +  +    PP +  T   HHQ                   HGN  P   PPP  
Sbjct: 460 GPFPPSTGAQSTAHPPVS--THHHHHQQQQQQQQQQQQQQQQQQQHHGNSGP---PPPGA 514

Query: 682 DYVIPHPVHAFHSQISSHATSHPVAPPPPTHLASTAAPIPQHLPPTHQPISH 733
               PHP+    S    HA  HP A  P         P P HLPP H  +S+
Sbjct: 515 ---FPHPLEGGSSH---HA--HPYAMSPSLGSLRPYPPGPAHLPPPHSQVSY 558



 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 94/434 (21%), Positives = 140/434 (32%), Gaps = 97/434 (22%)

Query: 392 PTVVPTTSARMESQATSASINNSNPSTSEQASDTASAVTSSQPSTVSETSATLTSNSTTG 451
           P  +P  S+   +       ++S+ S++  +S ++S+ +S+ P   S+   +   +    
Sbjct: 356 PHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPP 415

Query: 452 TSIGDDSR-------RTTSSAVTETGPPAMP---RL------------PSCCPQHSPCGG 489
           TS+   ++          S AV   GPP  P   RL            PS   Q +    
Sbjct: 416 TSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPP 475

Query: 490 SSQNHHALGHPHTSCFQQHGHHFQHHHHHHHT--------PHPA----------VPVSPS 531
            S +HH          QQ     Q   HH ++        PHP             +SPS
Sbjct: 476 VSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPS 535

Query: 532 FSD----PACPVERPPQVQAPCGANSSSGTSYHEQQALPVDLSNSGIRSHGSGSFHGASA 587
                  P  P   PP        +S    S       PV  S++   S   GS+     
Sbjct: 536 LGSLRPYPPGPAHLPPP-------HSQVSYSQAGPNGPPVSSSSNSSSSTSQGSY----- 583

Query: 588 FDPCCPVSSSRAAI-----FGHQAAAAAPSQPLSSIDGYGSSMVAQPQPQPPPQPSLSSC 642
             PC   S S+        F         S  LS++    +S  A  +   PP P     
Sbjct: 584 --PCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGK 641

Query: 643 RHYMPPPYASLTRPLHHQASACPHSHGNPPPQ--TQPP-------PQVDYVIPHPVHAFH 693
           R   P  Y + T P +   S      G PP    T PP       P    V P P+    
Sbjct: 642 RAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLP--- 698

Query: 694 SQISSHATSHPVAPPPPTHLAS-------------------TAAPIPQHLPPTHQPISHH 734
               +  +  P  PPPP   AS                     +P+P    P+  P    
Sbjct: 699 ---PAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVD 755

Query: 735 IPATAPPAQRLHPH 748
           +P+ A  + R + H
Sbjct: 756 VPSHASQSARFNKH 769


>gi|55750041 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 61.2 bits (147), Expect = 5e-09
 Identities = 118/513 (23%), Positives = 165/513 (32%), Gaps = 84/513 (16%)

Query: 349 SQGSSSHASRPQEPRNRSRISTVIQPLRQNAAEVVDLTVDEDEPTVVPT-TSARME---- 403
           +  S   A + ++   ++R+     P         +++  E E T  P  T    E    
Sbjct: 40  TSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRP 99

Query: 404 ---SQATSASINNSNPSTSEQASDTASAVTSSQPSTVSETSATLTSNSTTGTSIGDDSRR 460
              S   S    + N   S    D      S+ PS  S  S    S+S++G S G     
Sbjct: 100 QSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGP---- 155

Query: 461 TTSSAVTETGPPAMPRLPSCCPQHSPCGGSSQNHHALGHPHTSCFQQHGHHFQHH---HH 517
               A     PP  P      P   P   + +   A   PH S     G+H         
Sbjct: 156 ----ARPYHPPPLFP------PSPQPPDSTPRQPEASFEPHPSVTPT-GYHAPMEPPTSR 204

Query: 518 HHHTPHPAVPVSPSF--SDPACPVERPPQVQAPCGANSS----SGTSYHEQQALPVDLSN 571
               P  A P  P          +  PP      GA SS    +G   H     P+ +S+
Sbjct: 205 MFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSS 264

Query: 572 SGIRSH----------GSGSFHGA---SAFDPCCPVSSSRAAIFGHQAAAAAP----SQP 614
           SG              G G+   A   + F    P      A+     A+A+P    +QP
Sbjct: 265 SGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQP 324

Query: 615 LS----SIDGYGSSMVAQPQPQPPPQPSLSSCRHYMPPPYASLTRP-------LHHQASA 663
           L     S    G  M   P P P   P+L+   H +PP  +S   P           +SA
Sbjct: 325 LPGHLPSPHAMGQGMGGLP-PGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSA 383

Query: 664 CPHSHGNPPPQTQPPPQVDYVIPHPVHAFHSQISSHATSHPV---------------APP 708
              S  +    +  P      +P   H+F    S   ++ P                 PP
Sbjct: 384 AASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPP 443

Query: 709 PPTHLASTAAPIPQHLPPTHQPISHHIPATA-PPAQRLHPHEVMQRMEVQRRRMMQHPTR 767
           PP       A    H  P   P S    +TA PP    H H   Q+ + Q+++  Q   +
Sbjct: 444 PPPPYGRLLANSNAH--PGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQ 501

Query: 768 AH---ERPPPHPHRMHP-NYGHGHHIHVPQTMS 796
            H     PPP     HP   G  HH H P  MS
Sbjct: 502 QHHGNSGPPPPGAFPHPLEGGSSHHAH-PYAMS 533



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 59/232 (25%), Positives = 79/232 (34%), Gaps = 45/232 (19%)

Query: 524 PAVPVSPSFSDPACPVERPPQVQAPCGANSSSGTSYHEQQALPVDLSNSGIRSHGSGSFH 583
           P +  SP    PA      P ++ P  ++SSS  +           S+S   S  S S  
Sbjct: 350 PTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAA----------ASSSSSSSSSSASPF 399

Query: 584 GASAFDPCCPVS---SSRAAIFGHQAAAAAPSQPLSSIDGYG-------SSMVAQPQPQP 633
            AS   P  P S    +  ++         PS P  ++   G         ++A     P
Sbjct: 400 PASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHP 459

Query: 634 PPQPSLSSCRHYMPPPYASLTRPLHHQASACPHS------------HGNPPPQTQPPPQV 681
            P P  +  +    PP +  T   HHQ                   HGN  P   PPP  
Sbjct: 460 GPFPPSTGAQSTAHPPVS--THHHHHQQQQQQQQQQQQQQQQQQQHHGNSGP---PPPGA 514

Query: 682 DYVIPHPVHAFHSQISSHATSHPVAPPPPTHLASTAAPIPQHLPPTHQPISH 733
               PHP+    S    HA  HP A  P         P P HLPP H  +S+
Sbjct: 515 ---FPHPLEGGSSH---HA--HPYAMSPSLGSLRPYPPGPAHLPPPHSQVSY 558



 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 94/434 (21%), Positives = 140/434 (32%), Gaps = 97/434 (22%)

Query: 392 PTVVPTTSARMESQATSASINNSNPSTSEQASDTASAVTSSQPSTVSETSATLTSNSTTG 451
           P  +P  S+   +       ++S+ S++  +S ++S+ +S+ P   S+   +   +    
Sbjct: 356 PHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPP 415

Query: 452 TSIGDDSR-------RTTSSAVTETGPPAMP---RL------------PSCCPQHSPCGG 489
           TS+   ++          S AV   GPP  P   RL            PS   Q +    
Sbjct: 416 TSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPP 475

Query: 490 SSQNHHALGHPHTSCFQQHGHHFQHHHHHHHT--------PHPA----------VPVSPS 531
            S +HH          QQ     Q   HH ++        PHP             +SPS
Sbjct: 476 VSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPS 535

Query: 532 FSD----PACPVERPPQVQAPCGANSSSGTSYHEQQALPVDLSNSGIRSHGSGSFHGASA 587
                  P  P   PP        +S    S       PV  S++   S   GS+     
Sbjct: 536 LGSLRPYPPGPAHLPPP-------HSQVSYSQAGPNGPPVSSSSNSSSSTSQGSY----- 583

Query: 588 FDPCCPVSSSRAAI-----FGHQAAAAAPSQPLSSIDGYGSSMVAQPQPQPPPQPSLSSC 642
             PC   S S+        F         S  LS++    +S  A  +   PP P     
Sbjct: 584 --PCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGK 641

Query: 643 RHYMPPPYASLTRPLHHQASACPHSHGNPPPQ--TQPP-------PQVDYVIPHPVHAFH 693
           R   P  Y + T P +   S      G PP    T PP       P    V P P+    
Sbjct: 642 RAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLP--- 698

Query: 694 SQISSHATSHPVAPPPPTHLAS-------------------TAAPIPQHLPPTHQPISHH 734
               +  +  P  PPPP   AS                     +P+P    P+  P    
Sbjct: 699 ---PAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVD 755

Query: 735 IPATAPPAQRLHPH 748
           +P+ A  + R + H
Sbjct: 756 VPSHASQSARFNKH 769


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 60.5 bits (145), Expect = 8e-09
 Identities = 85/410 (20%), Positives = 152/410 (37%), Gaps = 25/410 (6%)

Query: 57   NSKVGNEFSHLCDDSQKQEKEMNGNQQEQEKSLVVRKKRKSQQAGPSYVQNCVKENQGIL 116
            NS   ++ S+  D S   +   + +  + + S        S  +  S   +    +    
Sbjct: 790  NSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSD 849

Query: 117  GLRQHLGTPSDEDNDSSFSDCLSSPSSSLHFGDSDTVTSDEDKEVSVRHSQTILNAKSRS 176
            G        SD  N S  SD   S +SS     SD+  S    + S   + +  ++   S
Sbjct: 850  GSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSS 909

Query: 177  HSARSHKWPRTETESVSGLLMKRPCLHGSSLRRLPCRKRFVKNNSSQRTQKQKERILMQR 236
            +S+ S     +   S S                         +NSS  +           
Sbjct: 910  NSSDSSDSSNSSDSSESS-------------------NSSDNSNSSDSSNSSDSSDSSDS 950

Query: 237  KKREVLARRKYALLPSSSSSSENDLSSESSSSSSTEGEEDLFVSASENHQNNPAVPSGSI 296
                  +    +   S SS S +  SS+SS+SS +    D   S+  +  +N +  S S 
Sbjct: 951  SNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1010

Query: 297  DEDVVVIEASSTPQVTANEEINVTSTDSEVEIVTVGESYRSRSTLGHSRSHWSQGS-SSH 355
            D        SS    ++N   +  S+DS     +   S  S S+     S+ S  S SS 
Sbjct: 1011 DSS-----DSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1065

Query: 356  ASRPQEPRNRSRISTVIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSN 415
            +S   +  + S  S   +    + +     + D  + +    +S   +S  +S S N+S+
Sbjct: 1066 SSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSD 1125

Query: 416  PSTSEQASDTASAVTSSQPSTVSETSATLTSNSTTGTSIGDDSRRTTSSA 465
             S S  +SD++ +  SS  S  SE+S +  S+ ++ +S   DS  ++ S+
Sbjct: 1126 SSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSS 1175



 Score = 57.0 bits (136), Expect = 9e-08
 Identities = 81/408 (19%), Positives = 146/408 (35%), Gaps = 27/408 (6%)

Query: 57  NSKVGNEFSHLCDDSQKQEKEMNGNQQEQEKSLVVRKKRKSQQAGPSYVQNCVKENQGIL 116
           +S   ++ S   D S   + + + ++ E + S    K   S         N    +    
Sbjct: 603 DSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNS 662

Query: 117 GLRQHLGTPSDEDNDSSFSDCLSSPSSSLHFGDSDTVTSDEDKEVSVRHSQTILNAKSRS 176
                    SD  + SS SD  +S  SS     SD+  S E  + S        ++   S
Sbjct: 663 SNSSDSSDSSDSSDSSSSSDSSNSSDSS---DSSDSSNSSESSDSSDSSDSDSSDSSDSS 719

Query: 177 HSARSHKWPRTETESVSGLLMKRPCLHGSSLRRLPCRKRFVKNNSSQRTQKQKERILMQR 236
           +S  S       ++S              S            +NSS  +           
Sbjct: 720 NSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSS-------- 771

Query: 237 KKREVLARRKYALLPSSSSSSENDLSSESSSSSSTEGEEDLFVSASENHQNNPAVPSGSI 296
                           SS SS++  SS+S+ SS++    D   S+  ++ ++ +  S S 
Sbjct: 772 ---------------DSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSS 816

Query: 297 DEDVVVIEASSTPQVTANEEINVTSTDSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHA 356
           D D      SS    +++   +  S+DS            +RS   +S        SS++
Sbjct: 817 DSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNS 876

Query: 357 SRPQEPRNRSRISTVIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNP 416
           S   +  + +  S        + +   D + D    +    +S   +S  +S S +NSN 
Sbjct: 877 SDSSDSSDSNESSNSSDSSDSSNSSDSDSS-DSSNSSDSSDSSNSSDSSESSNSSDNSNS 935

Query: 417 STSEQASDTASAVTSSQPSTVSETSATLTSNSTTGTSIGDDSRRTTSS 464
           S S  +SD++ +  SS  S  S +S +  S+ ++ ++  D S  + SS
Sbjct: 936 SDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSS 983



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 84/400 (21%), Positives = 154/400 (38%), Gaps = 42/400 (10%)

Query: 70  DSQKQEKEMNGNQQEQEKSLVVRKKRKSQQAGPSYVQNCVKENQGILGLRQHLGTPSDED 129
           D      E NGN     +S        S +   SY  +  K+N    G         D+D
Sbjct: 463 DDPNSSDESNGNDDANSES----DNNSSSRGDASYNSDESKDN----GNGSDSKGAEDDD 514

Query: 130 NDSSFSDCLSSPSSSLHFGDSDTVTSDEDKEVSVRHSQTILNAKSRSHSARSHKWPRTET 189
           +DS+     S  + + + G+ D   SD  K  S        ++ + S S+ S     +++
Sbjct: 515 SDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDS 574

Query: 190 ESVSGLLMKRPCLHGSSLRRLPCRKRFVKNNSSQRTQKQKERILMQRKKREVLARRKYAL 249
            S S           SS            ++SS  +                 +  K   
Sbjct: 575 NSSSD--------SDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDS 626

Query: 250 LPSSSSSSENDLSSESSSSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASSTP 309
             S S SS++D  S+SS S+S++  ++   S S N  N+      S   D      SS+ 
Sbjct: 627 SKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSD------SSSS 680

Query: 310 QVTANEEINVTSTDSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSRIS 369
             ++N   +  S+DS        ES  S  +     S  S  S+S++S            
Sbjct: 681 SDSSNSSDSSDSSDSS----NSSESSDSSDSSDSDSSDSSDSSNSNSSDSDS-------- 728

Query: 370 TVIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSEQASDTASAV 429
                   N+++  D +   D      ++++  +S  +S S N+S+ S S  +SD++ + 
Sbjct: 729 -------SNSSDSSDSSNSSDSSDSSDSSNSS-DSSDSSDSSNSSDSSDSSDSSDSSDSS 780

Query: 430 TSSQPSTVSETSATLTSNSTTGTSIGDDSRRTTSSAVTET 469
            SS  +  S +S +  S++++ +S   DS  ++ S+ +++
Sbjct: 781 NSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDS 820



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 48/212 (22%), Positives = 96/212 (45%), Gaps = 1/212 (0%)

Query: 253  SSSSSENDLSSESSSSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASSTPQVT 312
            SS+SS++  SS+SS SS +    D   S+  +  +N +  S S D       + S+    
Sbjct: 1021 SSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1080

Query: 313  ANEEINVTSTDSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSRISTVI 372
            ++E  + + + +  +     +S  S  +   S S  S  SS+ +       +     +  
Sbjct: 1081 SSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN 1140

Query: 373  QPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSEQASDTASAVTSS 432
                 +++E  D + D  + +    +S   +S  +S S N+S+ S S  +SD++ +  SS
Sbjct: 1141 SSDSSDSSESSDSS-DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1199

Query: 433  QPSTVSETSATLTSNSTTGTSIGDDSRRTTSS 464
              S  S++S +  S+ ++ +S   DS  ++ S
Sbjct: 1200 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1231



 Score = 47.4 bits (111), Expect = 7e-05
 Identities = 84/403 (20%), Positives = 147/403 (36%), Gaps = 28/403 (6%)

Query: 57   NSKVGNEFSHLCDDSQKQEKEMNGNQQEQEKSLVVRKKRKSQQAGPSYVQNCVKENQGIL 116
            NS   ++ S+  D S+      N N  +   S        S  +  S   N    +    
Sbjct: 910  NSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDS--SNSSDSSNSSD 967

Query: 117  GLRQHLGTPSDEDNDSSFSDCLSSPSSSLHFGDSDTVTSDEDKEVSVRHSQTILNAKSRS 176
                +    SD  N S  SD   S  SS    DS   ++  D   S   S +  ++ S +
Sbjct: 968  SSDSNSSDSSDSSNSSDSSDSSDSSDSS----DSSDSSNSSDSSDSSDSSDSSNSSDSSN 1023

Query: 177  HSARSHKWPRTETESVSGLLMKRPCLHGSSLRRLPCRKRFVKNNSSQRTQKQKERILMQR 236
             S  S+    +++   S           S             +NSS  +           
Sbjct: 1024 SSDSSNSSDSSDSSDSSDSSDSSDSSDSSD-----------SSNSSDSSDSSDSSDSSDS 1072

Query: 237  KKREVLARRKYALLPSSSSSSENDLSSESSSSSSTEGEEDLFVSASENHQNNPAVPSGSI 296
                  +    +    SS SS +  SS+SS SS +    D   S+  +  +N +  S S 
Sbjct: 1073 SDSSDSSDSSES--SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1130

Query: 297  DEDVVVIEASSTPQVTANEEINVT-STDSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSH 355
            D       ++S+    ++E  + + S+DS     +   S  S S+   + S  S  S S 
Sbjct: 1131 DSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1190

Query: 356  ASRPQEPRNRSRISTVIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSN 415
             S      + S  S+       ++++  D + D  + +    +S   +S  +S S ++S+
Sbjct: 1191 DSSDSSDSSDSSDSS-------DSSDSSDSS-DSSDSSDSSDSSDSSDSNESSDSSDSSD 1242

Query: 416  PSTSEQASDTASAVTSSQPSTVSETSATLTSNSTTGTSIGDDS 458
             S S  +SD++ +  SS  ++ S   +   S S  G + G DS
Sbjct: 1243 SSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDS 1285



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 74/373 (19%), Positives = 136/373 (36%), Gaps = 48/373 (12%)

Query: 252 SSSSSSENDLSSESSSSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASSTPQV 311
           S  S+  +D +SES ++SS+ G+   + S       N +   G+ D+D      S +   
Sbjct: 468 SDESNGNDDANSESDNNSSSRGDAS-YNSDESKDNGNGSDSKGAEDDD------SDSTSD 520

Query: 312 TANEEINVTSTDSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSRISTV 371
           T N + N    +        G     +S  G  +S  S   SS +S   +  + S     
Sbjct: 521 TNNSDSNGNGNN--------GNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSS----- 567

Query: 372 IQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSEQASDTASAVTS 431
                 + +   + + D D      + S+  +S  +S S ++S+ S S  +SD++ +  S
Sbjct: 568 -----DSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 622

Query: 432 SQPSTVSETSATLTSNSTTGTSIGDDSRRTTSSAVTETGPPAMPRLPSCCPQHSPCGGSS 491
              S+ SE+     S+ +   S   DS  + SS  +++   +     S     S    SS
Sbjct: 623 KSDSSKSESD----SSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSS 678

Query: 492 QNHHALGHPHTSCFQQHGHHFQHHHHHHHTPHPAVPVSPSFSDPACPVERPPQVQAPCGA 551
            +  +     +S      +  +       +   +   S S                   +
Sbjct: 679 SSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDS-------------------S 719

Query: 552 NSSSGTSYHEQQALPVDLSNSGIRSHGSGSFHGASAFDPCCPVSSSRAAIFGHQAAAAAP 611
           NS+S  S     +   D SNS   S  S S + + + D     +SS ++     + ++  
Sbjct: 720 NSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDS 779

Query: 612 SQPLSSIDGYGSS 624
           S    S D   SS
Sbjct: 780 SNSSDSNDSSNSS 792


>gi|209180481 Cas-Br-M (murine) ecotropic retroviral transforming
           sequence-like 1 [Homo sapiens]
          Length = 491

 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 41/133 (30%), Positives = 55/133 (41%), Gaps = 13/133 (9%)

Query: 634 PPQPSLSSCRHYMPPPYASLTRPLHHQASACPHSHGNPPPQTQPPPQVDYVIPHPV---- 689
           PP P+ +   H+  P Y       H      P  H  PPP   PPP + + +PHP     
Sbjct: 308 PPPPAPAPAHHH--PEYQGQPVVSHPHHIMPPQQHYAPPPP--PPPPISHPMPHPPQAAG 363

Query: 690 --HAFHSQISSH--ATSHPVAPPPPTHLASTAAPIPQHLPPTHQPISH-HIPATAPPAQR 744
             H  +SQ       ++ P   PPP H+ +   P   H PP   P  H   P TAPP   
Sbjct: 364 TPHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPPPHH 423

Query: 745 LHPHEVMQRMEVQ 757
            +P+ + Q  E Q
Sbjct: 424 YNPNSLPQFTEDQ 436



 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 56/219 (25%), Positives = 76/219 (34%), Gaps = 42/219 (19%)

Query: 516 HHHHHTPHPAVPVSPSFSDPACPVERPPQVQAPCGANSSSGTSYHEQQ-ALPV-DLSNSG 573
           H H++ PH  +   P+    A     PP  ++         T  H     +P+ D SNSG
Sbjct: 250 HEHYNQPHEDIRAPPAELSMA-----PPPPRSVSQETFRISTRKHSNLITVPIQDDSNSG 304

Query: 574 IRSHGSGSFHGASAFDPCCPVSSSRAAIFGHQAAAAAPSQPLSSIDGYGSSMVAQPQPQP 633
            R              P  P  +     +  Q   + P   +     Y         P P
Sbjct: 305 AREP-----------PPPAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYA--------PPP 345

Query: 634 PPQPSLSSCRHYMP-PPYASLTRPLHHQASACPHSHGNPPPQTQPPPQVDYVIPHPVHAF 692
           PP P +S   H MP PP A+ T  L +  +  P     PPP T PP  +           
Sbjct: 346 PPPPPIS---HPMPHPPQAAGTPHLVYSQAPPPPMTSAPPPITPPPGHI----------- 391

Query: 693 HSQISSHATSHPVAPPPPTHLA-STAAPIPQHLPPTHQP 730
            +Q+  +    P  PPPP H      AP P H  P   P
Sbjct: 392 IAQMPPYMNHPPPGPPPPQHGGPPVTAPPPHHYNPNSLP 430



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 64/247 (25%), Positives = 75/247 (30%), Gaps = 59/247 (23%)

Query: 631 PQPPPQPSLSSCRHYMPPPYASLTRPLHHQASACPHSH-GNPPPQTQPPPQVDYVIPHPV 689
           P   P P+    R  MPP         HH +   P  H   PPP  Q  P   Y  PH  
Sbjct: 207 PPIAPPPTEIPERFIMPPDK-------HHMSHIPPKQHIMMPPPPLQHVPHEHYNQPH-- 257

Query: 690 HAFHSQISSHATSHPVAPPPP-----------THLASTAAPIP----------QHLPPTH 728
                 I +      +APPPP           T   S    +P          +  PP  
Sbjct: 258 ----EDIRAPPAELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPPPPAP 313

Query: 729 QPISHHIPATAPPAQRLHPHEVMQRMEVQRRRMMQHPTRAHERPPPHPHRM-HPNYGHGH 787
            P  HH      P    HPH +M           QH       PPP  H M HP    G 
Sbjct: 314 APAHHHPEYQGQPVVS-HPHHIMP--------PQQHYAPPPPPPPPISHPMPHPPQAAG- 363

Query: 788 HIHVPQTMSSHPRQAPERSAWELGIEAGVTAATYTPGALHPHLAHY--HAPPRLHHLQLG 845
               P  + S     P  SA            T  PG +   +  Y  H PP     Q G
Sbjct: 364 ---TPHLVYSQAPPPPMTSA--------PPPITPPPGHIIAQMPPYMNHPPPGPPPPQHG 412

Query: 846 ALPLMVP 852
             P+  P
Sbjct: 413 GPPVTAP 419



 Score = 38.9 bits (89), Expect = 0.024
 Identities = 43/178 (24%), Positives = 54/178 (30%), Gaps = 52/178 (29%)

Query: 703 HPVAPPPPTHLASTAAPIPQHLPPTHQPISHHIPATAPPAQRL------HPHEVMQRMEV 756
           HP   PPPT +       P     +H P   HI    PP Q +       PHE ++    
Sbjct: 206 HPPIAPPPTEIPERFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEHYNQPHEDIRAPPA 265

Query: 757 QRRRMMQHP-----------TRAHER-------------------PPPHPHRMHPNY--- 783
           +       P           TR H                     P P P   HP Y   
Sbjct: 266 ELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPPPPAPAPAHHHPEYQGQ 325

Query: 784 ---GHGHHIHVPQTMSSHPRQAPERSAWELGIEAGVTAATYTPGAL-HPHLAHYHAPP 837
               H HHI  PQ   + P   P   +  +          + P A   PHL +  APP
Sbjct: 326 PVVSHPHHIMPPQQHYAPPPPPPPPISHPM---------PHPPQAAGTPHLVYSQAPP 374


>gi|7657520 ring finger protein 11 [Homo sapiens]
          Length = 154

 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 25/63 (39%), Positives = 38/63 (60%), Gaps = 1/63 (1%)

Query: 922 GEEGTEEDTEEKCTICLSILEEGEDVRRLPCMHLFHQVCVDQWLITNKKCPICRVDIEAQ 981
           G +G+E+   E C IC+     G+ +R LPCMH++H  C+D WL+ +  CP C   ++A 
Sbjct: 88  GRDGSEKKIRE-CVICMMDFVYGDPIRFLPCMHIYHLDCIDDWLMRSFTCPSCMEPVDAA 146

Query: 982 LPS 984
           L S
Sbjct: 147 LLS 149


>gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 58/216 (26%), Positives = 91/216 (42%), Gaps = 21/216 (9%)

Query: 263  SESSSSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASSTPQVTANEEINVTST 322
            SE+++++STEG E    S +E  +   A    S       I + +T   T   E   TST
Sbjct: 840  SETTTTTSTEGSETTTAS-TEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTST 898

Query: 323  DSEVEIV--TVGESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSRISTVIQPLRQNAA 380
            +        T G    + ST G   +  S   S   +   E    + +ST         +
Sbjct: 899  EGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTT-------GS 951

Query: 381  EVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSEQASD--TASAVTSSQPSTVS 438
            E + ++ +  E T V T    M S+ T+AS   S  +T   A    T +++  S+ +TVS
Sbjct: 952  ETITVSAEGSETTTVTT----MGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVS 1007

Query: 439  ETSATLTSNSTTG-----TSIGDDSRRTTSSAVTET 469
             T +  T+ STTG     TS       T ++A +ET
Sbjct: 1008 STGSETTTVSTTGTETTITSTEGSETTTVTTAGSET 1043



 Score = 53.5 bits (127), Expect = 9e-07
 Identities = 51/215 (23%), Positives = 85/215 (39%), Gaps = 16/215 (7%)

Query: 266 SSSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASSTPQVTANEEINVTSTDSE 325
           ++++STEG E    S S++     +               + T   T +E    ++T  E
Sbjct: 433 TTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLE 492

Query: 326 VEIV-TVGESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSRISTV---IQPLRQNAAE 381
              V T+G    + ST G   +  S   S   +   E    + +ST       +     E
Sbjct: 493 TTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLE 552

Query: 382 VVDLTVDEDEPTVVPTTSAR-----MESQATSASINNSNPSTSEQASD-------TASAV 429
               + +  E T V TT A       E   T+A+    + +T+   +D       TA + 
Sbjct: 553 TTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE 612

Query: 430 TSSQPSTVSETSATLTSNSTTGTSIGDDSRRTTSS 464
           T+S  +T SET+   T++S T T+  + S  TT S
Sbjct: 613 TTSASTTGSETTTASTTSSETTTASTEGSETTTVS 647



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 54/234 (23%), Positives = 102/234 (43%), Gaps = 26/234 (11%)

Query: 251 PSSSSSSENDLSSESSSSSSTEGEEDLFVSASENHQNNPA-------VPSGSIDEDVVVI 303
           P+ S ++   +S    +++ST G E+  VS++ +     +       V +   +   V I
Sbjct: 50  PTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSI 109

Query: 304 EASSTPQVTA--NEEINVTSTDSEVEIV-TVGESYRSRSTLGHSRSHWSQGSSSHASRPQ 360
             + T  V+A  +E    ++T SE  +  T G    + ST+G   S  +   ++ +    
Sbjct: 110 TGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVG---SETTTAYTADSETTA 166

Query: 361 EPRNRSRISTVIQPLRQN------AAEVVDLTVDEDEPTVVPTTSARMESQATSASINNS 414
                S ++TV     +        +E   ++    E T V TT +      T+++ ++ 
Sbjct: 167 ASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSET---TTASTAHSE 223

Query: 415 NPSTSEQASDTASAVTSSQPSTVS----ETSATLTSNSTTGTSIGDDSRRTTSS 464
             + S   S+T    T+   +TVS    ET+A  T +S T T+  +DS+ TT+S
Sbjct: 224 TTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTAS 277



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 54/231 (23%), Positives = 99/231 (42%), Gaps = 28/231 (12%)

Query: 253 SSSSSENDLSSESSSSS--STEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASSTPQ 310
           S++ SE  +S+E S ++  S  G E   VS + +     +     I          +T  
Sbjct: 677 SATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI----------TTAS 726

Query: 311 VTANEEINVTSTDSEVEIV-TVGESYRSRSTLGHSRSHWSQGSSSHASRP---QEPRNRS 366
           +T +E    ++  SE     T G    S ST G   +  S  SS          E    S
Sbjct: 727 ITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMAS 786

Query: 367 RISTVIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASI--------NNSNPST 418
            I +    +   ++++  +  +  E T+  TT++   + +T+ S         + +  +T
Sbjct: 787 TIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTT 846

Query: 419 SEQASDTASAVTSSQPSTVSETSATLTSNSTTGTSIGDDSRRTTSSAVTET 469
           S + S+T +A T    +T   T++T +S +TT T+IG ++  T S+  +ET
Sbjct: 847 STEGSETTTASTEGSETT---TASTESSETTTATTIGSET-TTASTEGSET 893



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 50/218 (22%), Positives = 91/218 (41%), Gaps = 15/218 (6%)

Query: 252  SSSSSSENDLSSESSSSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASSTPQV 311
            SS +++   + SE++++S TEG E    +++E  +   A   GS    V    + +T   
Sbjct: 870  SSETTTATTIGSETTTAS-TEGSETT-TTSTEGSETTTASTEGSEITTVSTTGSETTTAS 927

Query: 312  TANEEINVTSTDSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSRISTV 371
            T   E    ST+   E+ TV  +     T+    S     +++  +   E    S   + 
Sbjct: 928  TEGSETTTASTEGS-ELTTVSTTGSETITVSAEGSE----TTTVTTMGSETTTASTAGSE 982

Query: 372  IQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSEQASDTASAVTS 431
               +    +E    +++  E T V +T +   + +T+ +       TS + S+T +  T+
Sbjct: 983  TTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGT---ETTITSTEGSETTTVTTA 1039

Query: 432  SQPSTV-----SETSATLTSNSTTGTSIGDDSRRTTSS 464
               +T      SET+ T T  S T T     S  TT+S
Sbjct: 1040 GSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAS 1077



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 57/227 (25%), Positives = 95/227 (41%), Gaps = 15/227 (6%)

Query: 252  SSSSSSENDLSSESS--SSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASSTP 309
            S++ S     S+E S  +++STEG E   VS + +     +   GS    V  + + +T 
Sbjct: 917  STTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSA-EGSETTTVTTMGSETTT 975

Query: 310  QVTANEEINVTSTDSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSRIS 369
              TA  E    ST    E  T        +T+  + S  +  S++           S  +
Sbjct: 976  ASTAGSETTTVSTAGS-ETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETT 1034

Query: 370  TVIQPLRQNAA------EVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSEQAS 423
            TV     +  A      E    + +  E T V TT +   + A++A +  +  STS   +
Sbjct: 1035 TVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTT-ASTADLETTTVSTSGSGT 1093

Query: 424  DTASAVTSSQPSTVSETSATLTSNSTTG---TSIGDDSRRTTSSAVT 467
             TAS    S+ +TV  T +  T+ ST G   T++   S  TT+++ T
Sbjct: 1094 TTAS-TAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTT 1139



 Score = 47.4 bits (111), Expect = 7e-05
 Identities = 55/224 (24%), Positives = 92/224 (41%), Gaps = 26/224 (11%)

Query: 266 SSSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASSTPQVTANEEINVTSTD-S 324
           ++++STEG E   VSA+ +     +   GS +  V    + +T   T   E   TST+ S
Sbjct: 503 TTTASTEGSETTAVSATGSEMTTVST-EGSENTTVSTTGSETTTVSTTGLETTTTSTEGS 561

Query: 325 EVEIV-----------TVGESYRSRSTLGHSRSHWSQGSSSH---ASRPQEPRNRSRIST 370
           E+  V           T G    + ST G   +  S   S +   ++   E  + S   +
Sbjct: 562 EMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGS 621

Query: 371 VIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPS-TSEQASDTASAV 429
                   ++E    + +  E T V TT    +S+ T  S   S  + TS + S+T +  
Sbjct: 622 ETTTASTTSSETTTASTEGSETTTVSTT----DSETTMVSTTGSERTITSTEGSETTTVS 677

Query: 430 TSSQPSTVS-----ETSATLTSNSTTGTSIGDDSRRTTSSAVTE 468
            +   +TVS      T+ ++T + TT  S       TTS+  +E
Sbjct: 678 ATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSE 721



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 58/238 (24%), Positives = 96/238 (40%), Gaps = 20/238 (8%)

Query: 252 SSSSSSENDLSSESSS---SSSTEGEEDLFVSASENH---------QNNPAVPSGSIDED 299
           +S+  SE  ++S S S   ++STEG E   V+ + +          +   A  +G     
Sbjct: 436 ASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTT 495

Query: 300 VVVIEASSTPQVTANEEIN-VTSTDSEVEIV-TVGESYRSRSTLGHSRSHWSQGSSSHAS 357
           V  I + +T   T   E   V++T SE+  V T G    + ST G   +  S       +
Sbjct: 496 VFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTT 555

Query: 358 RPQEPRNRSRISTVIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPS 417
              E    + +ST       ++ E    T      +   T S       T+++ ++   S
Sbjct: 556 TSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTS 615

Query: 418 TSEQASDTASA-VTSSQPSTVS-----ETSATLTSNSTTGTSIGDDSRRTTSSAVTET 469
            S   S+T +A  TSS+ +T S      T+ + T + TT  S     R  TS+  +ET
Sbjct: 616 ASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSET 673



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 56/234 (23%), Positives = 93/234 (39%), Gaps = 24/234 (10%)

Query: 252 SSSSSSENDLSSESSSSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASS---T 308
           +S++SSE  ++S + S ++T        + +    +     S +  E   V  A S   T
Sbjct: 127 NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETIT 186

Query: 309 PQVTANEEINVTSTDSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSRI 368
           P    +E   V++  SE   V+   S  + ++  HS +  +    S  ++     + + +
Sbjct: 187 PSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTV 246

Query: 369 STVIQPLRQNAAE--VVDLTVDEDEPTVVPTTSARMESQATSASINNSNPS-TSEQASDT 425
           ST        + E    +    ED  T   TT++    + T+AS   S P+  S   S+T
Sbjct: 247 STAGSETTAASTEDSETNTAFTEDSKT---TTASTTGFETTAASTTGSEPTMASTMGSET 303

Query: 426 ASAVT-----------SSQPSTV----SETSATLTSNSTTGTSIGDDSRRTTSS 464
             A T           SS+ +TV    SET    T  S T T     S  TT+S
Sbjct: 304 TMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTAS 357



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 58/244 (23%), Positives = 100/244 (40%), Gaps = 34/244 (13%)

Query: 253  SSSSSENDLSSESSSSS---STEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASSTP 309
            SS+ SE    S + + +   STEG E   V+ + +     AV +   +      E S T 
Sbjct: 1007 SSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETT--AVYTTGSETTTTSTEGSETT 1064

Query: 310  QVTANEEINVTSTDSEVEIVTVGESYRSRSTLGHSRSHWS------QGSSSHASRPQEPR 363
             V+       T++ +++E  TV  S    +T   + S  +        +++ ++   E  
Sbjct: 1065 TVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEAT 1124

Query: 364  NRSRISTVIQPLRQNAAEVVDLTVDEDEPTVVPT------TSARMESQATSASINNSNPS 417
              S  S+         +E+  +     E T V T      TS+   S+AT+ S   S  +
Sbjct: 1125 TVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETT 1184

Query: 418  TSEQA-----------SDTASAVTSSQPSTVSETSATLTSNS-TTGTSIGDDSRRTTSSA 465
            T+  A           S+T +A T+   +T + TS + T+ + TTG+        T SSA
Sbjct: 1185 TASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETS-----TPSSA 1239

Query: 466  VTET 469
             +ET
Sbjct: 1240 GSET 1243



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 58/235 (24%), Positives = 95/235 (40%), Gaps = 24/235 (10%)

Query: 249 LLPSSSSSSENDLSSESSSSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASST 308
           L+ +S +++ +   SE+++ S T G +   VS S +     +  +GS +  V    + +T
Sbjct: 29  LIKASETTTASTAGSETTTPSPT-GSQTTIVSISGSEITTTST-AGSENTTVSSAGSGTT 86

Query: 309 PQVTANEEINVTSTDSEVEIVTV-GESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSR 367
               A  E  V++  SE   V++ G      S +G   +  S  SS            + 
Sbjct: 87  TASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTT 146

Query: 368 ISTVIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSEQASDTAS 427
           +STV        +E       + E T   TT + M +  T+ S     PST+   + T S
Sbjct: 147 VSTV-------GSETTTAYTADSETTAASTTGSEMTTVFTAGS-ETITPSTAGSETTTVS 198

Query: 428 ---------AVTSSQPSTVS----ETSATLTSNSTTGTSIGDDSRRTTSSAVTET 469
                    + T S+ +T S    ET+A  T  S T       S  T S+A +ET
Sbjct: 199 TAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSET 253



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 51/221 (23%), Positives = 87/221 (39%), Gaps = 47/221 (21%)

Query: 252 SSSSSSENDLSSESS--SSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASSTP 309
           S + S     S+E S  +++STEG E                              +++ 
Sbjct: 726 SITGSETTTASTEGSETTTASTEGSE------------------------------TTSA 755

Query: 310 QVTANEEINVTSTDSEVEIVTV-GESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSRI 368
             T +E    ++T SE  + ++ G      ST+G   +  S  SS   +   E    +  
Sbjct: 756 STTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIA 815

Query: 369 STVIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSEQASDTASA 428
           ST        A+E    TV       +P ++A  E+  T+++  +   + S + S+T +A
Sbjct: 816 ST-------TASETT--TVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTA 866

Query: 429 VTSSQPSTV-----SETSATLTSNSTTGTSIGDDSRRTTSS 464
            T S  +T      SET+   T  S T T+  + S  TT+S
Sbjct: 867 STESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTAS 907



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 52/221 (23%), Positives = 94/221 (42%), Gaps = 22/221 (9%)

Query: 248 ALLPSSSSSSENDLSSESSSSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASS 307
           A +  S +S+++   SE++++S TEG E    S +E  +      +GS    V + ++ +
Sbjct: 356 ASIMGSETSTDSTTGSETTTAS-TEGSETTTAS-TEGSEATTVSTTGSETTTVSITDSET 413

Query: 308 TPQVTANEEINVTSTDSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSR 367
           T   T   E+   ST       TV E+  + ST G   +  S   S   +   E    + 
Sbjct: 414 TTTCTEGSEMTAVST-------TVFET-TTASTEGSEITIASTSDSETTTASTEGSETTT 465

Query: 368 ISTVIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSEQASDTAS 427
           ++T         +E         E T    T     +  T  S  ++  +++E +  TA 
Sbjct: 466 VTTA-------GSETKTAYTTGSETTTASNTGLETTTVFTIGS--DTTTASTEGSETTAV 516

Query: 428 AVTSSQPSTVSETSATLTSNSTTG---TSIGDDSRRTTSSA 465
           + T S+ +TVS   +  T+ STTG   T++      TT+++
Sbjct: 517 SATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTS 557



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 55/221 (24%), Positives = 88/221 (39%), Gaps = 23/221 (10%)

Query: 249 LLPSSSSSSENDLSSESSSSS--STEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEAS 306
           + PS++ S    +S+  S ++  ST G E    +AS  H    A  +   +   V    S
Sbjct: 185 ITPSTAGSETTTVSTAGSETTTVSTTGSET--TTASTAHSETTAASTMGSETTKVSTAGS 242

Query: 307 STPQVTANEEINVTST-DSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNR 365
            T   TA  E    ST DSE       +S   ++T   +    +  +S+  S P      
Sbjct: 243 ETTVSTAGSETTAASTEDSETNTAFTEDS---KTTTASTTGFETTAASTTGSEP------ 293

Query: 366 SRISTVIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMES--QATSASINNSNPSTSEQAS 423
           +  ST+        +E    +    E T V T S+ + +   A S +I  S   +     
Sbjct: 294 TMASTM-------GSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTV 346

Query: 424 DTASAVTSSQPSTVSETSATLTSNSTTGTSIGDDSRRTTSS 464
            T  + T++     SETS   T+ S T T+  + S  TT+S
Sbjct: 347 STTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTAS 387



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 58/248 (23%), Positives = 102/248 (41%), Gaps = 29/248 (11%)

Query: 253  SSSSSENDLSSESSSSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASSTPQVT 312
            S +++ + + SE+++SS+   E     +++E  +   A  +GS         + +T   T
Sbjct: 1151 SETTTVSTIGSEATTSSAAGSEAT--TTSTEGSETTTASTAGSETTTASTAGSETTTAST 1208

Query: 313  ANEEINVTST---DSEVEIVTVGESYRSRSTLGHSRSHWSQGS----SSHASRPQEPRNR 365
            A  E    ST   ++     T  E+    S    + + +  GS    +S AS      + 
Sbjct: 1209 AGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSL 1268

Query: 366  SRISTVIQPLRQNAAEVVDLTVDED--------EPTVVPTTSARME-SQATSASINNSNP 416
            +   T    +  + A     TV           + ++ P T+  M  ++ T   +  S+ 
Sbjct: 1269 TGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSS 1328

Query: 417  STSEQASD-TASAVTSSQPSTVSETS----ATLTSNSTTG-----TSIGDDSRRTTSSAV 466
             T     D TASA + + P  V  TS    +T+ ++STT      T+ G  +R  TSS  
Sbjct: 1329 VTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGS-TREPTSSTF 1387

Query: 467  TETGPPAM 474
             ETGP +M
Sbjct: 1388 QETGPVSM 1395



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 55/231 (23%), Positives = 97/231 (41%), Gaps = 24/231 (10%)

Query: 252 SSSSSSENDLSSESSSSSSTEGEEDLFVSASENHQNNPAVPS--GSIDEDVVVIEASSTP 309
           +S+  SE + +    S ++T        +A+    + P + S  GS       I   +T 
Sbjct: 256 ASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTK 315

Query: 310 QVTANEEIN-VTSTDSE-VEIVTVGESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSR 367
             TA+ E+  V +  SE +   TVG    + ST G   +  S   S  ++        + 
Sbjct: 316 VSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTT 375

Query: 368 ISTVIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTS--EQASDT 425
            ST         +E    + +  E T V TT     S+ T+ SI +S  +T+  E +  T
Sbjct: 376 AST-------EGSETTTASTEGSEATTVSTTG----SETTTVSITDSETTTTCTEGSEMT 424

Query: 426 ASAVTSSQPSTVSETSATLT------SNSTTGTSIGDDSRR-TTSSAVTET 469
           A + T  + +T S   + +T      S +TT ++ G ++   TT+ + T+T
Sbjct: 425 AVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKT 475



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 44/208 (21%), Positives = 85/208 (40%), Gaps = 17/208 (8%)

Query: 252  SSSSSSEND---LSSESSSSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASST 308
            +S++ SE     ++   ++++STEG E   VS + +     +     +      +  ++T
Sbjct: 1096 ASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTT 1155

Query: 309  PQVTANEEINVTSTDSEVEIV-TVGESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSR 367
                 +E    ++  SE     T G    + ST G   +  S   S   +        + 
Sbjct: 1156 VSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTT 1215

Query: 368  ISTVIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSEQAS--DT 425
             ST        +    +        T  P+++    S+  +A I  S  + +  AS   T
Sbjct: 1216 AST--------SGSETNTACTTGSETSTPSSAG---SETNTAFIIGSETTIASTASLEPT 1264

Query: 426  ASAVTSSQPSTVSETSATLTSNSTTGTS 453
            A+++T S+ +TVS T++  T+ STT +S
Sbjct: 1265 ATSLTGSETTTVSITASGATAASTTVSS 1292


>gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 58/216 (26%), Positives = 91/216 (42%), Gaps = 21/216 (9%)

Query: 263  SESSSSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASSTPQVTANEEINVTST 322
            SE+++++STEG E    S +E  +   A    S       I + +T   T   E   TST
Sbjct: 840  SETTTTTSTEGSETTTAS-TEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTST 898

Query: 323  DSEVEIV--TVGESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSRISTVIQPLRQNAA 380
            +        T G    + ST G   +  S   S   +   E    + +ST         +
Sbjct: 899  EGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTT-------GS 951

Query: 381  EVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSEQASD--TASAVTSSQPSTVS 438
            E + ++ +  E T V T    M S+ T+AS   S  +T   A    T +++  S+ +TVS
Sbjct: 952  ETITVSAEGSETTTVTT----MGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVS 1007

Query: 439  ETSATLTSNSTTG-----TSIGDDSRRTTSSAVTET 469
             T +  T+ STTG     TS       T ++A +ET
Sbjct: 1008 STGSETTTVSTTGTETTITSTEGSETTTVTTAGSET 1043



 Score = 53.5 bits (127), Expect = 9e-07
 Identities = 51/215 (23%), Positives = 85/215 (39%), Gaps = 16/215 (7%)

Query: 266 SSSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASSTPQVTANEEINVTSTDSE 325
           ++++STEG E    S S++     +               + T   T +E    ++T  E
Sbjct: 433 TTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLE 492

Query: 326 VEIV-TVGESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSRISTV---IQPLRQNAAE 381
              V T+G    + ST G   +  S   S   +   E    + +ST       +     E
Sbjct: 493 TTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLE 552

Query: 382 VVDLTVDEDEPTVVPTTSAR-----MESQATSASINNSNPSTSEQASD-------TASAV 429
               + +  E T V TT A       E   T+A+    + +T+   +D       TA + 
Sbjct: 553 TTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE 612

Query: 430 TSSQPSTVSETSATLTSNSTTGTSIGDDSRRTTSS 464
           T+S  +T SET+   T++S T T+  + S  TT S
Sbjct: 613 TTSASTTGSETTTASTTSSETTTASTEGSETTTVS 647



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 54/234 (23%), Positives = 102/234 (43%), Gaps = 26/234 (11%)

Query: 251 PSSSSSSENDLSSESSSSSSTEGEEDLFVSASENHQNNPA-------VPSGSIDEDVVVI 303
           P+ S ++   +S    +++ST G E+  VS++ +     +       V +   +   V I
Sbjct: 50  PTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSI 109

Query: 304 EASSTPQVTA--NEEINVTSTDSEVEIV-TVGESYRSRSTLGHSRSHWSQGSSSHASRPQ 360
             + T  V+A  +E    ++T SE  +  T G    + ST+G   S  +   ++ +    
Sbjct: 110 TGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVG---SETTTAYTADSETTA 166

Query: 361 EPRNRSRISTVIQPLRQN------AAEVVDLTVDEDEPTVVPTTSARMESQATSASINNS 414
                S ++TV     +        +E   ++    E T V TT +      T+++ ++ 
Sbjct: 167 ASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSET---TTASTAHSE 223

Query: 415 NPSTSEQASDTASAVTSSQPSTVS----ETSATLTSNSTTGTSIGDDSRRTTSS 464
             + S   S+T    T+   +TVS    ET+A  T +S T T+  +DS+ TT+S
Sbjct: 224 TTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTAS 277



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 62/236 (26%), Positives = 100/236 (42%), Gaps = 28/236 (11%)

Query: 253  SSSSSENDLSSESSSSS---STEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASSTP 309
            SS+ SE    S + + +   STEG E   V+ + +     AV +   +      E S T 
Sbjct: 1007 SSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETT--AVYTTGSETTTTSTEGSETT 1064

Query: 310  QVTANEEINVTSTDSEVEIVTV---GESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRS 366
             V+       T++ +++E  TV   G    + ST G   +      S   +   E    +
Sbjct: 1065 TVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEAT 1124

Query: 367  RISTVIQPLRQNAAEVVDLTVDEDEPTVV------PTTSARMESQATSASINNSNPST-S 419
             +ST        ++E    +    E T V       TT + + S+AT++S   S  +T S
Sbjct: 1125 TVSTT-------SSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTS 1177

Query: 420  EQASDTASAVTSSQPSTV-----SETSATLTSNSTTGTSIGDDSRRTT-SSAVTET 469
             + S+T +A T+   +T      SET+   TS S T T+    S  +T SSA +ET
Sbjct: 1178 TEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSET 1233



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 54/231 (23%), Positives = 99/231 (42%), Gaps = 28/231 (12%)

Query: 253 SSSSSENDLSSESSSSS--STEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASSTPQ 310
           S++ SE  +S+E S ++  S  G E   VS + +     +     I          +T  
Sbjct: 677 SATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI----------TTAS 726

Query: 311 VTANEEINVTSTDSEVEIV-TVGESYRSRSTLGHSRSHWSQGSSSHASRP---QEPRNRS 366
           +T +E    ++  SE     T G    S ST G   +  S  SS          E    S
Sbjct: 727 ITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMAS 786

Query: 367 RISTVIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASI--------NNSNPST 418
            I +    +   ++++  +  +  E T+  TT++   + +T+ S         + +  +T
Sbjct: 787 TIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTT 846

Query: 419 SEQASDTASAVTSSQPSTVSETSATLTSNSTTGTSIGDDSRRTTSSAVTET 469
           S + S+T +A T    +T   T++T +S +TT T+IG ++  T S+  +ET
Sbjct: 847 STEGSETTTASTEGSETT---TASTESSETTTATTIGSET-TTASTEGSET 893



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 50/218 (22%), Positives = 91/218 (41%), Gaps = 15/218 (6%)

Query: 252  SSSSSSENDLSSESSSSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASSTPQV 311
            SS +++   + SE++++S TEG E    +++E  +   A   GS    V    + +T   
Sbjct: 870  SSETTTATTIGSETTTAS-TEGSETT-TTSTEGSETTTASTEGSEITTVSTTGSETTTAS 927

Query: 312  TANEEINVTSTDSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSRISTV 371
            T   E    ST+   E+ TV  +     T+    S     +++  +   E    S   + 
Sbjct: 928  TEGSETTTASTEGS-ELTTVSTTGSETITVSAEGSE----TTTVTTMGSETTTASTAGSE 982

Query: 372  IQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSEQASDTASAVTS 431
               +    +E    +++  E T V +T +   + +T+ +       TS + S+T +  T+
Sbjct: 983  TTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGT---ETTITSTEGSETTTVTTA 1039

Query: 432  SQPSTV-----SETSATLTSNSTTGTSIGDDSRRTTSS 464
               +T      SET+ T T  S T T     S  TT+S
Sbjct: 1040 GSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAS 1077



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 57/227 (25%), Positives = 95/227 (41%), Gaps = 15/227 (6%)

Query: 252  SSSSSSENDLSSESS--SSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASSTP 309
            S++ S     S+E S  +++STEG E   VS + +     +   GS    V  + + +T 
Sbjct: 917  STTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSA-EGSETTTVTTMGSETTT 975

Query: 310  QVTANEEINVTSTDSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSRIS 369
              TA  E    ST    E  T        +T+  + S  +  S++           S  +
Sbjct: 976  ASTAGSETTTVSTAGS-ETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETT 1034

Query: 370  TVIQPLRQNAA------EVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSEQAS 423
            TV     +  A      E    + +  E T V TT +   + A++A +  +  STS   +
Sbjct: 1035 TVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTT-ASTADLETTTVSTSGSGT 1093

Query: 424  DTASAVTSSQPSTVSETSATLTSNSTTG---TSIGDDSRRTTSSAVT 467
             TAS    S+ +TV  T +  T+ ST G   T++   S  TT+++ T
Sbjct: 1094 TTAS-TAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTT 1139



 Score = 47.4 bits (111), Expect = 7e-05
 Identities = 55/224 (24%), Positives = 92/224 (41%), Gaps = 26/224 (11%)

Query: 266 SSSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASSTPQVTANEEINVTSTD-S 324
           ++++STEG E   VSA+ +     +   GS +  V    + +T   T   E   TST+ S
Sbjct: 503 TTTASTEGSETTAVSATGSEMTTVST-EGSENTTVSTTGSETTTVSTTGLETTTTSTEGS 561

Query: 325 EVEIV-----------TVGESYRSRSTLGHSRSHWSQGSSSH---ASRPQEPRNRSRIST 370
           E+  V           T G    + ST G   +  S   S +   ++   E  + S   +
Sbjct: 562 EMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGS 621

Query: 371 VIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPS-TSEQASDTASAV 429
                   ++E    + +  E T V TT    +S+ T  S   S  + TS + S+T +  
Sbjct: 622 ETTTASTTSSETTTASTEGSETTTVSTT----DSETTMVSTTGSERTITSTEGSETTTVS 677

Query: 430 TSSQPSTVS-----ETSATLTSNSTTGTSIGDDSRRTTSSAVTE 468
            +   +TVS      T+ ++T + TT  S       TTS+  +E
Sbjct: 678 ATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSE 721



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 58/238 (24%), Positives = 96/238 (40%), Gaps = 20/238 (8%)

Query: 252 SSSSSSENDLSSESSS---SSSTEGEEDLFVSASENH---------QNNPAVPSGSIDED 299
           +S+  SE  ++S S S   ++STEG E   V+ + +          +   A  +G     
Sbjct: 436 ASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTT 495

Query: 300 VVVIEASSTPQVTANEEIN-VTSTDSEVEIV-TVGESYRSRSTLGHSRSHWSQGSSSHAS 357
           V  I + +T   T   E   V++T SE+  V T G    + ST G   +  S       +
Sbjct: 496 VFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTT 555

Query: 358 RPQEPRNRSRISTVIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPS 417
              E    + +ST       ++ E    T      +   T S       T+++ ++   S
Sbjct: 556 TSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTS 615

Query: 418 TSEQASDTASA-VTSSQPSTVS-----ETSATLTSNSTTGTSIGDDSRRTTSSAVTET 469
            S   S+T +A  TSS+ +T S      T+ + T + TT  S     R  TS+  +ET
Sbjct: 616 ASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSET 673



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 56/234 (23%), Positives = 93/234 (39%), Gaps = 24/234 (10%)

Query: 252 SSSSSSENDLSSESSSSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASS---T 308
           +S++SSE  ++S + S ++T        + +    +     S +  E   V  A S   T
Sbjct: 127 NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETIT 186

Query: 309 PQVTANEEINVTSTDSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSRI 368
           P    +E   V++  SE   V+   S  + ++  HS +  +    S  ++     + + +
Sbjct: 187 PSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTV 246

Query: 369 STVIQPLRQNAAE--VVDLTVDEDEPTVVPTTSARMESQATSASINNSNPS-TSEQASDT 425
           ST        + E    +    ED  T   TT++    + T+AS   S P+  S   S+T
Sbjct: 247 STAGSETTAASTEDSETNTAFTEDSKT---TTASTTGFETTAASTTGSEPTMASTMGSET 303

Query: 426 ASAVT-----------SSQPSTV----SETSATLTSNSTTGTSIGDDSRRTTSS 464
             A T           SS+ +TV    SET    T  S T T     S  TT+S
Sbjct: 304 TMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTAS 357



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 58/235 (24%), Positives = 95/235 (40%), Gaps = 24/235 (10%)

Query: 249 LLPSSSSSSENDLSSESSSSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASST 308
           L+ +S +++ +   SE+++ S T G +   VS S +     +  +GS +  V    + +T
Sbjct: 29  LIKASETTTASTAGSETTTPSPT-GSQTTIVSISGSEITTTST-AGSENTTVSSAGSGTT 86

Query: 309 PQVTANEEINVTSTDSEVEIVTV-GESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSR 367
               A  E  V++  SE   V++ G      S +G   +  S  SS            + 
Sbjct: 87  TASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTT 146

Query: 368 ISTVIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSEQASDTAS 427
           +STV        +E       + E T   TT + M +  T+ S     PST+   + T S
Sbjct: 147 VSTV-------GSETTTAYTADSETTAASTTGSEMTTVFTAGS-ETITPSTAGSETTTVS 198

Query: 428 ---------AVTSSQPSTVS----ETSATLTSNSTTGTSIGDDSRRTTSSAVTET 469
                    + T S+ +T S    ET+A  T  S T       S  T S+A +ET
Sbjct: 199 TAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSET 253



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 51/221 (23%), Positives = 87/221 (39%), Gaps = 47/221 (21%)

Query: 252 SSSSSSENDLSSESS--SSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASSTP 309
           S + S     S+E S  +++STEG E                              +++ 
Sbjct: 726 SITGSETTTASTEGSETTTASTEGSE------------------------------TTSA 755

Query: 310 QVTANEEINVTSTDSEVEIVTV-GESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSRI 368
             T +E    ++T SE  + ++ G      ST+G   +  S  SS   +   E    +  
Sbjct: 756 STTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIA 815

Query: 369 STVIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSEQASDTASA 428
           ST        A+E    TV       +P ++A  E+  T+++  +   + S + S+T +A
Sbjct: 816 ST-------TASETT--TVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTA 866

Query: 429 VTSSQPSTV-----SETSATLTSNSTTGTSIGDDSRRTTSS 464
            T S  +T      SET+   T  S T T+  + S  TT+S
Sbjct: 867 STESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTAS 907



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 52/221 (23%), Positives = 94/221 (42%), Gaps = 22/221 (9%)

Query: 248 ALLPSSSSSSENDLSSESSSSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASS 307
           A +  S +S+++   SE++++S TEG E    S +E  +      +GS    V + ++ +
Sbjct: 356 ASIMGSETSTDSTTGSETTTAS-TEGSETTTAS-TEGSEATTVSTTGSETTTVSITDSET 413

Query: 308 TPQVTANEEINVTSTDSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSR 367
           T   T   E+   ST       TV E+  + ST G   +  S   S   +   E    + 
Sbjct: 414 TTTCTEGSEMTAVST-------TVFET-TTASTEGSEITIASTSDSETTTASTEGSETTT 465

Query: 368 ISTVIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSEQASDTAS 427
           ++T         +E         E T    T     +  T  S  ++  +++E +  TA 
Sbjct: 466 VTTA-------GSETKTAYTTGSETTTASNTGLETTTVFTIGS--DTTTASTEGSETTAV 516

Query: 428 AVTSSQPSTVSETSATLTSNSTTG---TSIGDDSRRTTSSA 465
           + T S+ +TVS   +  T+ STTG   T++      TT+++
Sbjct: 517 SATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTS 557



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 55/221 (24%), Positives = 88/221 (39%), Gaps = 23/221 (10%)

Query: 249 LLPSSSSSSENDLSSESSSSS--STEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEAS 306
           + PS++ S    +S+  S ++  ST G E    +AS  H    A  +   +   V    S
Sbjct: 185 ITPSTAGSETTTVSTAGSETTTVSTTGSET--TTASTAHSETTAASTMGSETTKVSTAGS 242

Query: 307 STPQVTANEEINVTST-DSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNR 365
            T   TA  E    ST DSE       +S   ++T   +    +  +S+  S P      
Sbjct: 243 ETTVSTAGSETTAASTEDSETNTAFTEDS---KTTTASTTGFETTAASTTGSEP------ 293

Query: 366 SRISTVIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMES--QATSASINNSNPSTSEQAS 423
           +  ST+        +E    +    E T V T S+ + +   A S +I  S   +     
Sbjct: 294 TMASTM-------GSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTV 346

Query: 424 DTASAVTSSQPSTVSETSATLTSNSTTGTSIGDDSRRTTSS 464
            T  + T++     SETS   T+ S T T+  + S  TT+S
Sbjct: 347 STTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTAS 387



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 55/231 (23%), Positives = 97/231 (41%), Gaps = 24/231 (10%)

Query: 252 SSSSSSENDLSSESSSSSSTEGEEDLFVSASENHQNNPAVPS--GSIDEDVVVIEASSTP 309
           +S+  SE + +    S ++T        +A+    + P + S  GS       I   +T 
Sbjct: 256 ASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTK 315

Query: 310 QVTANEEIN-VTSTDSE-VEIVTVGESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSR 367
             TA+ E+  V +  SE +   TVG    + ST G   +  S   S  ++        + 
Sbjct: 316 VSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTT 375

Query: 368 ISTVIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTS--EQASDT 425
            ST         +E    + +  E T V TT     S+ T+ SI +S  +T+  E +  T
Sbjct: 376 AST-------EGSETTTASTEGSEATTVSTTG----SETTTVSITDSETTTTCTEGSEMT 424

Query: 426 ASAVTSSQPSTVSETSATLT------SNSTTGTSIGDDSRR-TTSSAVTET 469
           A + T  + +T S   + +T      S +TT ++ G ++   TT+ + T+T
Sbjct: 425 AVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKT 475



 Score = 39.7 bits (91), Expect = 0.014
 Identities = 57/245 (23%), Positives = 100/245 (40%), Gaps = 33/245 (13%)

Query: 253  SSSSSENDLSSESSSSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASSTPQVT 312
            S +++ + + SE+++SS+   E     +++E  +   A  +GS         + +T   T
Sbjct: 1151 SETTTVSTIGSEATTSSAAGSEAT--TTSTEGSETTTASTAGSETTTASTAGSETTTAST 1208

Query: 313  ANEEINVTSTDSEVEIVTVGESYRSRSTLGHSRSHWSQGS----SSHASRPQEPRNRSRI 368
            +  E N   T       T  E+    S    + + +  GS    +S AS      + +  
Sbjct: 1209 SGSETNTACT-------TGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGS 1261

Query: 369  STVIQPLRQNAAEVVDLTVDED--------EPTVVPTTSARME-SQATSASINNSNPSTS 419
             T    +  + A     TV           + ++ P T+  M  ++ T   +  S+  T 
Sbjct: 1262 ETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTM 1321

Query: 420  EQASD-TASAVTSSQPSTVSETS----ATLTSNSTTG-----TSIGDDSRRTTSSAVTET 469
                D TASA + + P  V  TS    +T+ ++STT      T+ G  +R  TSS   ET
Sbjct: 1322 APGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGS-TREPTSSTFQET 1380

Query: 470  GPPAM 474
            GP +M
Sbjct: 1381 GPVSM 1385



 Score = 39.3 bits (90), Expect = 0.018
 Identities = 44/201 (21%), Positives = 78/201 (38%), Gaps = 16/201 (7%)

Query: 262  SSESSSSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASSTPQVTANEEINVTS 321
            S   ++++ST G E   V  + +     +               ++T   T +E   V +
Sbjct: 1089 SGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFT 1148

Query: 322  TDSEVEIV-TVGESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSRISTVIQPLRQNAA 380
            T SE   V T+G    + S  G   +  S   S   +        +  ST         +
Sbjct: 1149 TVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTA-------GS 1201

Query: 381  EVVDLTVDEDEPTVVPTTSARMESQATSASINN------SNPSTSEQAS--DTASAVTSS 432
            E    +    E     TT +   + +++ S  N      S  + +  AS   TA+++T S
Sbjct: 1202 ETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGS 1261

Query: 433  QPSTVSETSATLTSNSTTGTS 453
            + +TVS T++  T+ STT +S
Sbjct: 1262 ETTTVSITASGATAASTTVSS 1282


>gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 58/216 (26%), Positives = 91/216 (42%), Gaps = 21/216 (9%)

Query: 263  SESSSSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASSTPQVTANEEINVTST 322
            SE+++++STEG E    S +E  +   A    S       I + +T   T   E   TST
Sbjct: 840  SETTTTTSTEGSETTTAS-TEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTST 898

Query: 323  DSEVEIV--TVGESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSRISTVIQPLRQNAA 380
            +        T G    + ST G   +  S   S   +   E    + +ST         +
Sbjct: 899  EGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTT-------GS 951

Query: 381  EVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSEQASD--TASAVTSSQPSTVS 438
            E + ++ +  E T V T    M S+ T+AS   S  +T   A    T +++  S+ +TVS
Sbjct: 952  ETITVSAEGSETTTVTT----MGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVS 1007

Query: 439  ETSATLTSNSTTG-----TSIGDDSRRTTSSAVTET 469
             T +  T+ STTG     TS       T ++A +ET
Sbjct: 1008 STGSETTTVSTTGTETTITSTEGSETTTVTTAGSET 1043



 Score = 53.5 bits (127), Expect = 9e-07
 Identities = 51/215 (23%), Positives = 85/215 (39%), Gaps = 16/215 (7%)

Query: 266 SSSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASSTPQVTANEEINVTSTDSE 325
           ++++STEG E    S S++     +               + T   T +E    ++T  E
Sbjct: 433 TTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLE 492

Query: 326 VEIV-TVGESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSRISTV---IQPLRQNAAE 381
              V T+G    + ST G   +  S   S   +   E    + +ST       +     E
Sbjct: 493 TTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLE 552

Query: 382 VVDLTVDEDEPTVVPTTSAR-----MESQATSASINNSNPSTSEQASD-------TASAV 429
               + +  E T V TT A       E   T+A+    + +T+   +D       TA + 
Sbjct: 553 TTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE 612

Query: 430 TSSQPSTVSETSATLTSNSTTGTSIGDDSRRTTSS 464
           T+S  +T SET+   T++S T T+  + S  TT S
Sbjct: 613 TTSASTTGSETTTASTTSSETTTASTEGSETTTVS 647



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 54/234 (23%), Positives = 102/234 (43%), Gaps = 26/234 (11%)

Query: 251 PSSSSSSENDLSSESSSSSSTEGEEDLFVSASENHQNNPA-------VPSGSIDEDVVVI 303
           P+ S ++   +S    +++ST G E+  VS++ +     +       V +   +   V I
Sbjct: 50  PTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSI 109

Query: 304 EASSTPQVTA--NEEINVTSTDSEVEIV-TVGESYRSRSTLGHSRSHWSQGSSSHASRPQ 360
             + T  V+A  +E    ++T SE  +  T G    + ST+G   S  +   ++ +    
Sbjct: 110 TGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVG---SETTTAYTADSETTA 166

Query: 361 EPRNRSRISTVIQPLRQN------AAEVVDLTVDEDEPTVVPTTSARMESQATSASINNS 414
                S ++TV     +        +E   ++    E T V TT +      T+++ ++ 
Sbjct: 167 ASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSET---TTASTAHSE 223

Query: 415 NPSTSEQASDTASAVTSSQPSTVS----ETSATLTSNSTTGTSIGDDSRRTTSS 464
             + S   S+T    T+   +TVS    ET+A  T +S T T+  +DS+ TT+S
Sbjct: 224 TTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTAS 277



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 54/231 (23%), Positives = 99/231 (42%), Gaps = 28/231 (12%)

Query: 253 SSSSSENDLSSESSSSS--STEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASSTPQ 310
           S++ SE  +S+E S ++  S  G E   VS + +     +     I          +T  
Sbjct: 677 SATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI----------TTAS 726

Query: 311 VTANEEINVTSTDSEVEIV-TVGESYRSRSTLGHSRSHWSQGSSSHASRP---QEPRNRS 366
           +T +E    ++  SE     T G    S ST G   +  S  SS          E    S
Sbjct: 727 ITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMAS 786

Query: 367 RISTVIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASI--------NNSNPST 418
            I +    +   ++++  +  +  E T+  TT++   + +T+ S         + +  +T
Sbjct: 787 TIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTT 846

Query: 419 SEQASDTASAVTSSQPSTVSETSATLTSNSTTGTSIGDDSRRTTSSAVTET 469
           S + S+T +A T    +T   T++T +S +TT T+IG ++  T S+  +ET
Sbjct: 847 STEGSETTTASTEGSETT---TASTESSETTTATTIGSET-TTASTEGSET 893



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 50/218 (22%), Positives = 91/218 (41%), Gaps = 15/218 (6%)

Query: 252  SSSSSSENDLSSESSSSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASSTPQV 311
            SS +++   + SE++++S TEG E    +++E  +   A   GS    V    + +T   
Sbjct: 870  SSETTTATTIGSETTTAS-TEGSETT-TTSTEGSETTTASTEGSEITTVSTTGSETTTAS 927

Query: 312  TANEEINVTSTDSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSRISTV 371
            T   E    ST+   E+ TV  +     T+    S     +++  +   E    S   + 
Sbjct: 928  TEGSETTTASTEGS-ELTTVSTTGSETITVSAEGSE----TTTVTTMGSETTTASTAGSE 982

Query: 372  IQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSEQASDTASAVTS 431
               +    +E    +++  E T V +T +   + +T+ +       TS + S+T +  T+
Sbjct: 983  TTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGT---ETTITSTEGSETTTVTTA 1039

Query: 432  SQPSTV-----SETSATLTSNSTTGTSIGDDSRRTTSS 464
               +T      SET+ T T  S T T     S  TT+S
Sbjct: 1040 GSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAS 1077



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 57/227 (25%), Positives = 95/227 (41%), Gaps = 15/227 (6%)

Query: 252  SSSSSSENDLSSESS--SSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASSTP 309
            S++ S     S+E S  +++STEG E   VS + +     +   GS    V  + + +T 
Sbjct: 917  STTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSA-EGSETTTVTTMGSETTT 975

Query: 310  QVTANEEINVTSTDSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSRIS 369
              TA  E    ST    E  T        +T+  + S  +  S++           S  +
Sbjct: 976  ASTAGSETTTVSTAGS-ETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETT 1034

Query: 370  TVIQPLRQNAA------EVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSEQAS 423
            TV     +  A      E    + +  E T V TT +   + A++A +  +  STS   +
Sbjct: 1035 TVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTT-ASTADLETTTVSTSGSGT 1093

Query: 424  DTASAVTSSQPSTVSETSATLTSNSTTG---TSIGDDSRRTTSSAVT 467
             TAS    S+ +TV  T +  T+ ST G   T++   S  TT+++ T
Sbjct: 1094 TTAS-TAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTT 1139



 Score = 47.4 bits (111), Expect = 7e-05
 Identities = 55/224 (24%), Positives = 92/224 (41%), Gaps = 26/224 (11%)

Query: 266 SSSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASSTPQVTANEEINVTSTD-S 324
           ++++STEG E   VSA+ +     +   GS +  V    + +T   T   E   TST+ S
Sbjct: 503 TTTASTEGSETTAVSATGSEMTTVST-EGSENTTVSTTGSETTTVSTTGLETTTTSTEGS 561

Query: 325 EVEIV-----------TVGESYRSRSTLGHSRSHWSQGSSSH---ASRPQEPRNRSRIST 370
           E+  V           T G    + ST G   +  S   S +   ++   E  + S   +
Sbjct: 562 EMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGS 621

Query: 371 VIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPS-TSEQASDTASAV 429
                   ++E    + +  E T V TT    +S+ T  S   S  + TS + S+T +  
Sbjct: 622 ETTTASTTSSETTTASTEGSETTTVSTT----DSETTMVSTTGSERTITSTEGSETTTVS 677

Query: 430 TSSQPSTVS-----ETSATLTSNSTTGTSIGDDSRRTTSSAVTE 468
            +   +TVS      T+ ++T + TT  S       TTS+  +E
Sbjct: 678 ATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSE 721



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 58/238 (24%), Positives = 96/238 (40%), Gaps = 20/238 (8%)

Query: 252 SSSSSSENDLSSESSS---SSSTEGEEDLFVSASENH---------QNNPAVPSGSIDED 299
           +S+  SE  ++S S S   ++STEG E   V+ + +          +   A  +G     
Sbjct: 436 ASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTT 495

Query: 300 VVVIEASSTPQVTANEEIN-VTSTDSEVEIV-TVGESYRSRSTLGHSRSHWSQGSSSHAS 357
           V  I + +T   T   E   V++T SE+  V T G    + ST G   +  S       +
Sbjct: 496 VFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTT 555

Query: 358 RPQEPRNRSRISTVIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPS 417
              E    + +ST       ++ E    T      +   T S       T+++ ++   S
Sbjct: 556 TSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTS 615

Query: 418 TSEQASDTASA-VTSSQPSTVS-----ETSATLTSNSTTGTSIGDDSRRTTSSAVTET 469
            S   S+T +A  TSS+ +T S      T+ + T + TT  S     R  TS+  +ET
Sbjct: 616 ASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSET 673



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 56/234 (23%), Positives = 93/234 (39%), Gaps = 24/234 (10%)

Query: 252 SSSSSSENDLSSESSSSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASS---T 308
           +S++SSE  ++S + S ++T        + +    +     S +  E   V  A S   T
Sbjct: 127 NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETIT 186

Query: 309 PQVTANEEINVTSTDSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSRI 368
           P    +E   V++  SE   V+   S  + ++  HS +  +    S  ++     + + +
Sbjct: 187 PSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTV 246

Query: 369 STVIQPLRQNAAE--VVDLTVDEDEPTVVPTTSARMESQATSASINNSNPS-TSEQASDT 425
           ST        + E    +    ED  T   TT++    + T+AS   S P+  S   S+T
Sbjct: 247 STAGSETTAASTEDSETNTAFTEDSKT---TTASTTGFETTAASTTGSEPTMASTMGSET 303

Query: 426 ASAVT-----------SSQPSTV----SETSATLTSNSTTGTSIGDDSRRTTSS 464
             A T           SS+ +TV    SET    T  S T T     S  TT+S
Sbjct: 304 TMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTAS 357



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 58/235 (24%), Positives = 95/235 (40%), Gaps = 24/235 (10%)

Query: 249 LLPSSSSSSENDLSSESSSSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASST 308
           L+ +S +++ +   SE+++ S T G +   VS S +     +  +GS +  V    + +T
Sbjct: 29  LIKASETTTASTAGSETTTPSPT-GSQTTIVSISGSEITTTST-AGSENTTVSSAGSGTT 86

Query: 309 PQVTANEEINVTSTDSEVEIVTV-GESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSR 367
               A  E  V++  SE   V++ G      S +G   +  S  SS            + 
Sbjct: 87  TASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTT 146

Query: 368 ISTVIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSEQASDTAS 427
           +STV        +E       + E T   TT + M +  T+ S     PST+   + T S
Sbjct: 147 VSTV-------GSETTTAYTADSETTAASTTGSEMTTVFTAGS-ETITPSTAGSETTTVS 198

Query: 428 ---------AVTSSQPSTVS----ETSATLTSNSTTGTSIGDDSRRTTSSAVTET 469
                    + T S+ +T S    ET+A  T  S T       S  T S+A +ET
Sbjct: 199 TAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSET 253



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 58/250 (23%), Positives = 102/250 (40%), Gaps = 35/250 (14%)

Query: 253  SSSSSENDLSSESSSSS---STEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASSTP 309
            SS+ SE    S + + +   STEG E   V+ + +     AV +   +      E S T 
Sbjct: 1007 SSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETT--AVYTTGSETTTTSTEGSETT 1064

Query: 310  QVTANEEINVTSTDSEVEIVTVGESYRSRSTLGHSRSHWS------QGSSSHASRPQEPR 363
             V+       T++ +++E  TV  S    +T   + S  +        +++ ++   E  
Sbjct: 1065 TVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEAT 1124

Query: 364  NRSRISTVIQPLRQNAAEVVDLTVDEDEPTVVPT------TSARMESQATSASINNSNPS 417
              S  S+         +E+  +     E T V T      TS+   S+AT+ S   S  +
Sbjct: 1125 TVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETT 1184

Query: 418  TSEQA-----------SDTASAVTSSQP-----STVSETSATLTSNSTTGTS--IGDDSR 459
            T+  A           S+T +A TS        +T SETS   ++ S T T+  IG +S 
Sbjct: 1185 TASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSEST 1244

Query: 460  RTTSSAVTET 469
              +++++  T
Sbjct: 1245 IASTASLEPT 1254



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 51/221 (23%), Positives = 87/221 (39%), Gaps = 47/221 (21%)

Query: 252 SSSSSSENDLSSESS--SSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASSTP 309
           S + S     S+E S  +++STEG E                              +++ 
Sbjct: 726 SITGSETTTASTEGSETTTASTEGSE------------------------------TTSA 755

Query: 310 QVTANEEINVTSTDSEVEIVTV-GESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSRI 368
             T +E    ++T SE  + ++ G      ST+G   +  S  SS   +   E    +  
Sbjct: 756 STTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIA 815

Query: 369 STVIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSEQASDTASA 428
           ST        A+E    TV       +P ++A  E+  T+++  +   + S + S+T +A
Sbjct: 816 ST-------TASETT--TVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTA 866

Query: 429 VTSSQPSTV-----SETSATLTSNSTTGTSIGDDSRRTTSS 464
            T S  +T      SET+   T  S T T+  + S  TT+S
Sbjct: 867 STESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTAS 907



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 52/221 (23%), Positives = 94/221 (42%), Gaps = 22/221 (9%)

Query: 248 ALLPSSSSSSENDLSSESSSSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASS 307
           A +  S +S+++   SE++++S TEG E    S +E  +      +GS    V + ++ +
Sbjct: 356 ASIMGSETSTDSTTGSETTTAS-TEGSETTTAS-TEGSEATTVSTTGSETTTVSITDSET 413

Query: 308 TPQVTANEEINVTSTDSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSR 367
           T   T   E+   ST       TV E+  + ST G   +  S   S   +   E    + 
Sbjct: 414 TTTCTEGSEMTAVST-------TVFET-TTASTEGSEITIASTSDSETTTASTEGSETTT 465

Query: 368 ISTVIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSEQASDTAS 427
           ++T         +E         E T    T     +  T  S  ++  +++E +  TA 
Sbjct: 466 VTTA-------GSETKTAYTTGSETTTASNTGLETTTVFTIGS--DTTTASTEGSETTAV 516

Query: 428 AVTSSQPSTVSETSATLTSNSTTG---TSIGDDSRRTTSSA 465
           + T S+ +TVS   +  T+ STTG   T++      TT+++
Sbjct: 517 SATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTS 557



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 55/221 (24%), Positives = 88/221 (39%), Gaps = 23/221 (10%)

Query: 249 LLPSSSSSSENDLSSESSSSS--STEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEAS 306
           + PS++ S    +S+  S ++  ST G E    +AS  H    A  +   +   V    S
Sbjct: 185 ITPSTAGSETTTVSTAGSETTTVSTTGSET--TTASTAHSETTAASTMGSETTKVSTAGS 242

Query: 307 STPQVTANEEINVTST-DSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNR 365
            T   TA  E    ST DSE       +S   ++T   +    +  +S+  S P      
Sbjct: 243 ETTVSTAGSETTAASTEDSETNTAFTEDS---KTTTASTTGFETTAASTTGSEP------ 293

Query: 366 SRISTVIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMES--QATSASINNSNPSTSEQAS 423
           +  ST+        +E    +    E T V T S+ + +   A S +I  S   +     
Sbjct: 294 TMASTM-------GSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTV 346

Query: 424 DTASAVTSSQPSTVSETSATLTSNSTTGTSIGDDSRRTTSS 464
            T  + T++     SETS   T+ S T T+  + S  TT+S
Sbjct: 347 STTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTAS 387



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 55/231 (23%), Positives = 97/231 (41%), Gaps = 24/231 (10%)

Query: 252 SSSSSSENDLSSESSSSSSTEGEEDLFVSASENHQNNPAVPS--GSIDEDVVVIEASSTP 309
           +S+  SE + +    S ++T        +A+    + P + S  GS       I   +T 
Sbjct: 256 ASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTK 315

Query: 310 QVTANEEIN-VTSTDSE-VEIVTVGESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSR 367
             TA+ E+  V +  SE +   TVG    + ST G   +  S   S  ++        + 
Sbjct: 316 VSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTT 375

Query: 368 ISTVIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTS--EQASDT 425
            ST         +E    + +  E T V TT     S+ T+ SI +S  +T+  E +  T
Sbjct: 376 AST-------EGSETTTASTEGSEATTVSTTG----SETTTVSITDSETTTTCTEGSEMT 424

Query: 426 ASAVTSSQPSTVSETSATLT------SNSTTGTSIGDDSRR-TTSSAVTET 469
           A + T  + +T S   + +T      S +TT ++ G ++   TT+ + T+T
Sbjct: 425 AVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKT 475



 Score = 40.0 bits (92), Expect = 0.011
 Identities = 42/201 (20%), Positives = 77/201 (38%), Gaps = 16/201 (7%)

Query: 262  SSESSSSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASSTPQVTANEEINVTS 321
            S   ++++ST G E   V  + +     +               ++T   T +E   V +
Sbjct: 1089 SGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFT 1148

Query: 322  TDSEVEIV-TVGESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSRISTVIQPLRQNAA 380
            T SE   V T+G    + S  G   +  S   S   +        +  ST         +
Sbjct: 1149 TVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTA-------GS 1201

Query: 381  EVVDLTVDEDEPTVVPTTSARMESQATSASINN--------SNPSTSEQASDTASAVTSS 432
            E    +    E     TT +   + +++ S  N        S  +++     TA+++T S
Sbjct: 1202 ETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSESTIASTASLEPTATSLTGS 1261

Query: 433  QPSTVSETSATLTSNSTTGTS 453
            + +TVS T++  T+ STT +S
Sbjct: 1262 ETTTVSITASGATAASTTVSS 1282



 Score = 40.0 bits (92), Expect = 0.011
 Identities = 57/242 (23%), Positives = 101/242 (41%), Gaps = 27/242 (11%)

Query: 253  SSSSSENDLSSESSSSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASSTPQVT 312
            S +++ + + SE+++SS+   E     +++E  +   A  +GS         + +T   T
Sbjct: 1151 SETTTVSTIGSEATTSSAAGSEAT--TTSTEGSETTTASTAGSETTTASTAGSETTTAST 1208

Query: 313  ANEEINVT-STDSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSRISTV 371
            +  E N   +T SE    +   S  + + +  S S      +S AS      + +   T 
Sbjct: 1209 SGSETNTACTTGSETSTPSSAGSETNTAFIIGSEST----IASTASLEPTATSLTGSETT 1264

Query: 372  IQPLRQNAAEVVDLTVDED--------EPTVVPTTSARME-SQATSASINNSNPSTSEQA 422
               +  + A     TV           + ++ P T+  M  ++ T   +  S+  T    
Sbjct: 1265 TVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPG 1324

Query: 423  SD-TASAVTSSQPSTVSETS----ATLTSNSTTG-----TSIGDDSRRTTSSAVTETGPP 472
             D TASA + + P  V  TS    +T+ ++STT      T+ G  +R  TSS   ETGP 
Sbjct: 1325 MDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGS-TREPTSSTFQETGPV 1383

Query: 473  AM 474
            +M
Sbjct: 1384 SM 1385


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.126    0.379 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,178,159
Number of Sequences: 37866
Number of extensions: 2783961
Number of successful extensions: 26525
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 334
Number of HSP's successfully gapped in prelim test: 1164
Number of HSP's that attempted gapping in prelim test: 14974
Number of HSP's gapped (non-prelim): 7347
length of query: 986
length of database: 18,247,518
effective HSP length: 112
effective length of query: 874
effective length of database: 14,006,526
effective search space: 12241703724
effective search space used: 12241703724
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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