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Search of human proteins with 34335272
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|34335272 endothelial protein C receptor precursor [Homo
sapiens]
(238 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|34335272 endothelial protein C receptor precursor [Homo sapiens] 485 e-137
gi|4502649 CD1D antigen precursor [Homo sapiens] 57 1e-08
gi|149158700 major histocompatibility complex, class I, F isofor... 45 6e-05
gi|62912479 major histocompatibility complex, class I, E precurs... 41 0.001
gi|52630342 major histocompatibility complex, class I, C precurs... 40 0.002
gi|149158702 major histocompatibility complex, class I, F isofor... 37 0.015
gi|149158698 major histocompatibility complex, class I, F isofor... 37 0.015
gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [H... 35 0.057
gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Hom... 35 0.057
gi|53829376 plakophilin 4 isoform b [Homo sapiens] 35 0.075
gi|53829374 plakophilin 4 isoform a [Homo sapiens] 35 0.075
gi|110618227 CD1C antigen precursor [Homo sapiens] 34 0.097
gi|24797067 major histocompatibility complex, class I, A precurs... 33 0.22
gi|4504415 major histocompatibility complex, class I, G precurso... 33 0.28
gi|17986001 major histocompatibility complex, class I, B precurs... 32 0.37
gi|89063265 PREDICTED: similar to MHC class I antigen [Homo sapi... 31 0.82
gi|229576885 endomucin isoform 2 [Homo sapiens] 28 7.0
gi|20070284 endomucin isoform 1 [Homo sapiens] 28 7.0
gi|239750064 PREDICTED: hypothetical protein XP_002347285 [Homo ... 28 9.1
gi|148529014 damage-specific DNA binding protein 1 [Homo sapiens] 28 9.1
gi|6912590 pleckstrin homology-like domain, family A, member 3 [... 28 9.1
>gi|34335272 endothelial protein C receptor precursor [Homo sapiens]
Length = 238
Score = 485 bits (1249), Expect = e-137
Identities = 238/238 (100%), Positives = 238/238 (100%)
Query: 1 MLTTLLPILLLSGWAFCSQDASDGLQRLHMLQISYFRDPYHVWYQGNASLGGHLTHVLEG 60
MLTTLLPILLLSGWAFCSQDASDGLQRLHMLQISYFRDPYHVWYQGNASLGGHLTHVLEG
Sbjct: 1 MLTTLLPILLLSGWAFCSQDASDGLQRLHMLQISYFRDPYHVWYQGNASLGGHLTHVLEG 60
Query: 61 PDTNTTIIQLQPLQEPESWARTQSGLQSYLLQFHGLVRLVHQERTLAFPLTIRCFLGCEL 120
PDTNTTIIQLQPLQEPESWARTQSGLQSYLLQFHGLVRLVHQERTLAFPLTIRCFLGCEL
Sbjct: 61 PDTNTTIIQLQPLQEPESWARTQSGLQSYLLQFHGLVRLVHQERTLAFPLTIRCFLGCEL 120
Query: 121 PPEGSRAHVFFEVAVNGSSFVSFRPERALWQADTQVTSGVVTFTLQQLNAYNRTRYELRE 180
PPEGSRAHVFFEVAVNGSSFVSFRPERALWQADTQVTSGVVTFTLQQLNAYNRTRYELRE
Sbjct: 121 PPEGSRAHVFFEVAVNGSSFVSFRPERALWQADTQVTSGVVTFTLQQLNAYNRTRYELRE 180
Query: 181 FLEDTCVQYVQKHISAENTKGSQTSRSYTSLVLGVLVGSFIIAGVAVGIFLCTGGRRC 238
FLEDTCVQYVQKHISAENTKGSQTSRSYTSLVLGVLVGSFIIAGVAVGIFLCTGGRRC
Sbjct: 181 FLEDTCVQYVQKHISAENTKGSQTSRSYTSLVLGVLVGSFIIAGVAVGIFLCTGGRRC 238
>gi|4502649 CD1D antigen precursor [Homo sapiens]
Length = 335
Score = 57.0 bits (136), Expect = 1e-08
Identities = 57/193 (29%), Positives = 83/193 (43%), Gaps = 12/193 (6%)
Query: 2 LTTLLPILLLSGWAFCSQDASDGLQRLHMLQISYFRDPYHVWYQGNASLGGHLTHVLEGP 61
L LL LL W S + L L LQIS F + G A LG TH
Sbjct: 4 LLFLLLWALLQAWG--SAEVPQRLFPLRCLQISSFANSSWTRTDGLAWLGELQTH--SWS 59
Query: 62 DTNTTIIQLQPLQE----PESWARTQSGLQSYLLQFHGLVRLVHQERTLAFPLTIRCFLG 117
+ + T+ L+P + + W Q + Y F V+ + L++PL ++ G
Sbjct: 60 NDSDTVRSLKPWSQGTFSDQQWETLQHIFRVYRSSFTRDVKEFAKMLRLSYPLELQVSAG 119
Query: 118 CELPPEGSRAHVFFEVAVNGSSFVSFRPERALWQADTQVTSGVVTFTLQQLNAYNRTRYE 177
CE+ P G+ ++ FF VA G +SF + W+ TQ V +Q LN TR
Sbjct: 120 CEVHP-GNASNNFFHVAFQGKDILSF--QGTSWE-PTQEAPLWVNLAIQVLNQDKWTRET 175
Query: 178 LREFLEDTCVQYV 190
++ L TC Q+V
Sbjct: 176 VQWLLNGTCPQFV 188
>gi|149158700 major histocompatibility complex, class I, F isoform 3
precursor [Homo sapiens]
Length = 254
Score = 45.1 bits (105), Expect = 6e-05
Identities = 36/179 (20%), Positives = 79/179 (44%), Gaps = 19/179 (10%)
Query: 62 DTNTTIIQLQPLQE------PESWART----QSGLQSYLLQFHGLVRLVHQERTLAFPLT 111
D++ I +++P + P+ W T ++ Q+ + L+R +Q A T
Sbjct: 58 DSDAAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSE--AGSHT 115
Query: 112 IRCFLGCELPPEGSRAHVFFEVAVNGSSFVSFRPERALWQADTQVTSGVVTFTLQQLNAY 171
++ GC++ P+G + + A +G ++S + W A V +T + Y
Sbjct: 116 LQGMNGCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQ--ITQRFYEAEEY 173
Query: 172 NRTRYELREFLEDTCVQYVQKHI--SAENTKGSQTSRSYTSLVLGVLVGSFIIAGVAVG 228
E R +LE C++ +++++ E + ++ S T ++G++ G ++ V G
Sbjct: 174 AE---EFRTYLEGECLELLRRYLENGKETLQRAEQSPQPTIPIVGIVAGLVVLGAVVTG 229
>gi|62912479 major histocompatibility complex, class I, E precursor
[Homo sapiens]
Length = 358
Score = 40.8 bits (94), Expect = 0.001
Identities = 24/94 (25%), Positives = 46/94 (48%), Gaps = 9/94 (9%)
Query: 111 TIRCFLGCELPPEGSRAHVFFEVAVNGSSFVSFRPERALWQADTQVTSGVVTFTLQQLNA 170
T++ GCEL P+G + + A +G +++ + W A + Q+ N
Sbjct: 115 TLQWMHGCELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTA----VDTAAQISEQKSND 170
Query: 171 YNRTRYELREFLEDTCVQYVQKHISAENTKGSQT 204
+ ++ R +LEDTCV+++ K++ KG +T
Sbjct: 171 ASEAEHQ-RAYLEDTCVEWLHKYLE----KGKET 199
>gi|52630342 major histocompatibility complex, class I, C precursor
[Homo sapiens]
Length = 366
Score = 40.0 bits (92), Expect = 0.002
Identities = 24/90 (26%), Positives = 46/90 (51%), Gaps = 7/90 (7%)
Query: 111 TIRCFLGCELPPEGSRAHVFFEVAVNGSSFVSFRPERALWQADTQVTSGVVTFTLQQLNA 170
T++ GC+L P+G + + A +G +++ + W A T ++L A
Sbjct: 118 TLQRMSGCDLGPDGRLLRGYDQSAYDGKDYIALNEDLRSWTA----ADTAAQITQRKLEA 173
Query: 171 YNRTRYELREFLEDTCVQYVQKHISAENTK 200
R +LR +LE TCV+++++++ EN K
Sbjct: 174 -ARAAEQLRAYLEGTCVEWLRRYL--ENGK 200
>gi|149158702 major histocompatibility complex, class I, F isoform 1
precursor [Homo sapiens]
Length = 442
Score = 37.0 bits (84), Expect = 0.015
Identities = 32/149 (21%), Positives = 66/149 (44%), Gaps = 19/149 (12%)
Query: 62 DTNTTIIQLQPLQE------PESWART----QSGLQSYLLQFHGLVRLVHQERTLAFPLT 111
D++ I +++P + P+ W T ++ Q+ + L+R +Q A T
Sbjct: 58 DSDAAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSE--AGSHT 115
Query: 112 IRCFLGCELPPEGSRAHVFFEVAVNGSSFVSFRPERALWQADTQVTSGVVTFTLQQLNAY 171
++ GC++ P+G + + A +G ++S + W A V +T + Y
Sbjct: 116 LQGMNGCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQ--ITQRFYEAEEY 173
Query: 172 NRTRYELREFLEDTCVQYVQKHISAENTK 200
E R +LE C++ +++++ EN K
Sbjct: 174 AE---EFRTYLEGECLELLRRYL--ENGK 197
>gi|149158698 major histocompatibility complex, class I, F isoform 2
precursor [Homo sapiens]
Length = 346
Score = 37.0 bits (84), Expect = 0.015
Identities = 32/149 (21%), Positives = 66/149 (44%), Gaps = 19/149 (12%)
Query: 62 DTNTTIIQLQPLQE------PESWART----QSGLQSYLLQFHGLVRLVHQERTLAFPLT 111
D++ I +++P + P+ W T ++ Q+ + L+R +Q A T
Sbjct: 58 DSDAAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSE--AGSHT 115
Query: 112 IRCFLGCELPPEGSRAHVFFEVAVNGSSFVSFRPERALWQADTQVTSGVVTFTLQQLNAY 171
++ GC++ P+G + + A +G ++S + W A V +T + Y
Sbjct: 116 LQGMNGCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQ--ITQRFYEAEEY 173
Query: 172 NRTRYELREFLEDTCVQYVQKHISAENTK 200
E R +LE C++ +++++ EN K
Sbjct: 174 AE---EFRTYLEGECLELLRRYL--ENGK 197
>gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [Homo
sapiens]
Length = 365
Score = 35.0 bits (79), Expect = 0.057
Identities = 25/86 (29%), Positives = 42/86 (48%), Gaps = 5/86 (5%)
Query: 109 PLTIRCFLGCELPPEGSRAHVFFEVAVNGSSFVSFRPERALWQADTQVTSGVVTFTLQQL 168
P T++ LGCEL P+ + + A+NG F++F ++ W D + QQ
Sbjct: 110 PYTLQGLLGCELGPDNTSVPT-AKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQD 168
Query: 169 NAYNRTRYELREFLEDTCVQYVQKHI 194
A N+ EL FL +C +++H+
Sbjct: 169 KAANK---EL-TFLLFSCPHRLREHL 190
>gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Homo
sapiens]
Length = 365
Score = 35.0 bits (79), Expect = 0.057
Identities = 25/86 (29%), Positives = 42/86 (48%), Gaps = 5/86 (5%)
Query: 109 PLTIRCFLGCELPPEGSRAHVFFEVAVNGSSFVSFRPERALWQADTQVTSGVVTFTLQQL 168
P T++ LGCEL P+ + + A+NG F++F ++ W D + QQ
Sbjct: 110 PYTLQGLLGCELGPDNTSVPT-AKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQD 168
Query: 169 NAYNRTRYELREFLEDTCVQYVQKHI 194
A N+ EL FL +C +++H+
Sbjct: 169 KAANK---EL-TFLLFSCPHRLREHL 190
>gi|53829376 plakophilin 4 isoform b [Homo sapiens]
Length = 1149
Score = 34.7 bits (78), Expect = 0.075
Identities = 40/150 (26%), Positives = 57/150 (38%), Gaps = 12/150 (8%)
Query: 61 PDTNTTIIQLQPLQEPESWART-QSGLQSYLLQFHGLVRLVHQERTLAFPLTIRCFLGCE 119
P T P EPE+ A T + ++ LQF L R + ER + RC LG E
Sbjct: 15 PQTRQEAASTGPGMEPETTATTILASVKEQELQFQRLTRELEVERQIVASQLERCRLGAE 74
Query: 120 LPPEGSRAHVFFEVAVNGSSFVSFRPERALWQADTQVTSGVVTFTLQQLNAYNRTRYELR 179
P +A S+ SF P R+ +T V+ V+ +Q N RT E
Sbjct: 75 SP----------SIASTSSTEKSF-PWRSTDVPNTGVSKPRVSDAVQPNNYLIRTEPEQG 123
Query: 180 EFLEDTCVQYVQKHISAENTKGSQTSRSYT 209
+ S N++ S SY+
Sbjct: 124 TLYSPEQTSLHESEGSLGNSRSSTQMNSYS 153
>gi|53829374 plakophilin 4 isoform a [Homo sapiens]
Length = 1192
Score = 34.7 bits (78), Expect = 0.075
Identities = 40/150 (26%), Positives = 57/150 (38%), Gaps = 12/150 (8%)
Query: 61 PDTNTTIIQLQPLQEPESWART-QSGLQSYLLQFHGLVRLVHQERTLAFPLTIRCFLGCE 119
P T P EPE+ A T + ++ LQF L R + ER + RC LG E
Sbjct: 15 PQTRQEAASTGPGMEPETTATTILASVKEQELQFQRLTRELEVERQIVASQLERCRLGAE 74
Query: 120 LPPEGSRAHVFFEVAVNGSSFVSFRPERALWQADTQVTSGVVTFTLQQLNAYNRTRYELR 179
P +A S+ SF P R+ +T V+ V+ +Q N RT E
Sbjct: 75 SP----------SIASTSSTEKSF-PWRSTDVPNTGVSKPRVSDAVQPNNYLIRTEPEQG 123
Query: 180 EFLEDTCVQYVQKHISAENTKGSQTSRSYT 209
+ S N++ S SY+
Sbjct: 124 TLYSPEQTSLHESEGSLGNSRSSTQMNSYS 153
>gi|110618227 CD1C antigen precursor [Homo sapiens]
Length = 333
Score = 34.3 bits (77), Expect = 0.097
Identities = 46/149 (30%), Positives = 65/149 (43%), Gaps = 13/149 (8%)
Query: 2 LTTLLPILLLSGWAFCSQDASDGLQRLHMLQISYFRDPYHVWYQGNASLGGHLTHVLEGP 61
L LL LLL G + DAS H++QI F + QG+ L TH G
Sbjct: 4 LQFLLLALLLPGGD--NADASQEHVSFHVIQIFSFVNQSWARGQGSGWLDELQTH---GW 58
Query: 62 DTNT-TIIQLQPLQEPESWARTQSGLQSYLLQFH--GLVRLVHQERTL---AFPLTIRCF 115
D+ + TII L + S L+ L +F+ GL R + + +P ++
Sbjct: 59 DSESGTIIFLHNWSKGNFSNEELSDLE-LLFRFYLFGLTREIQDHASQDYSKYPFEVQVK 117
Query: 116 LGCELPPEGSRAHVFFEVAVNGSSFVSFR 144
GCEL G FF+VA NG +SF+
Sbjct: 118 AGCELH-SGKSPEGFFQVAFNGLDLLSFQ 145
>gi|24797067 major histocompatibility complex, class I, A precursor
[Homo sapiens]
Length = 365
Score = 33.1 bits (74), Expect = 0.22
Identities = 20/90 (22%), Positives = 44/90 (48%), Gaps = 7/90 (7%)
Query: 111 TIRCFLGCELPPEGSRAHVFFEVAVNGSSFVSFRPERALWQADTQVTSGVVTFTLQQLNA 170
TI+ GC++ +G + + A +G +++ + W A T ++ A
Sbjct: 118 TIQIMYGCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQ----ITKRKWEA 173
Query: 171 YNRTRYELREFLEDTCVQYVQKHISAENTK 200
+ +LR +L+ TCV+++++++ EN K
Sbjct: 174 AHEAE-QLRAYLDGTCVEWLRRYL--ENGK 200
>gi|4504415 major histocompatibility complex, class I, G precursor
[Homo sapiens]
Length = 338
Score = 32.7 bits (73), Expect = 0.28
Identities = 20/90 (22%), Positives = 43/90 (47%), Gaps = 7/90 (7%)
Query: 111 TIRCFLGCELPPEGSRAHVFFEVAVNGSSFVSFRPERALWQADTQVTSGVVTFTLQQLNA 170
T++ +GC+L +G + + A +G +++ + W A + ++ A
Sbjct: 118 TLQWMIGCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTA----ADTAAQISKRKCEA 173
Query: 171 YNRTRYELREFLEDTCVQYVQKHISAENTK 200
N + R +LE TCV+++ +++ EN K
Sbjct: 174 AN-VAEQRRAYLEGTCVEWLHRYL--ENGK 200
>gi|17986001 major histocompatibility complex, class I, B precursor
[Homo sapiens]
Length = 362
Score = 32.3 bits (72), Expect = 0.37
Identities = 21/90 (23%), Positives = 44/90 (48%), Gaps = 7/90 (7%)
Query: 111 TIRCFLGCELPPEGSRAHVFFEVAVNGSSFVSFRPERALWQADTQVTSGVVTFTLQQLNA 170
T++ GC++ P+G + A +G +++ + W A T+ +T Q+
Sbjct: 118 TLQSMYGCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAAD--TAAQIT---QRKWE 172
Query: 171 YNRTRYELREFLEDTCVQYVQKHISAENTK 200
R + R +LE CV+++++++ EN K
Sbjct: 173 AAREAEQRRAYLEGECVEWLRRYL--ENGK 200
>gi|89063265 PREDICTED: similar to MHC class I antigen [Homo
sapiens]
Length = 366
Score = 31.2 bits (69), Expect = 0.82
Identities = 17/84 (20%), Positives = 38/84 (45%), Gaps = 5/84 (5%)
Query: 111 TIRCFLGCELPPEGSRAHVFFEVAVNGSSFVSFRPERALWQADTQVTSGVVTFTLQQLNA 170
T++ GC++ P+G F + A +G +++ + W A + + + A
Sbjct: 131 TLQLMYGCDVGPDGRFLRGFMQDAYDGRDYIALNEDLRSWTA-ADTAAQITKRKREAAGA 189
Query: 171 YNRTRYELREFLEDTCVQYVQKHI 194
R R +LE CV+ +++++
Sbjct: 190 AERQ----RNYLEGRCVEGLRRYL 209
>gi|229576885 endomucin isoform 2 [Homo sapiens]
Length = 248
Score = 28.1 bits (61), Expect = 7.0
Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 3/52 (5%)
Query: 183 EDTCVQYVQKHISAENTKGSQTSRSYTSLVLGVLVGSFIIAGVAVGIFLCTG 234
E+T V +N S TSRSY+S++L V++ +I + +F+ G
Sbjct: 150 ENTSQSQVIGTEGGKNASTSATSRSYSSIILPVVIALIVI---TLSVFVLVG 198
>gi|20070284 endomucin isoform 1 [Homo sapiens]
Length = 261
Score = 28.1 bits (61), Expect = 7.0
Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 3/52 (5%)
Query: 183 EDTCVQYVQKHISAENTKGSQTSRSYTSLVLGVLVGSFIIAGVAVGIFLCTG 234
E+T V +N S TSRSY+S++L V++ +I + +F+ G
Sbjct: 163 ENTSQSQVIGTEGGKNASTSATSRSYSSIILPVVIALIVI---TLSVFVLVG 211
>gi|239750064 PREDICTED: hypothetical protein XP_002347285 [Homo
sapiens]
Length = 1140
Score = 27.7 bits (60), Expect = 9.1
Identities = 14/50 (28%), Positives = 25/50 (50%)
Query: 23 DGLQRLHMLQISYFRDPYHVWYQGNASLGGHLTHVLEGPDTNTTIIQLQP 72
D +Q+LH+ + + P + YQ + G L+ +E DT+ L+P
Sbjct: 705 DEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRP 754
>gi|148529014 damage-specific DNA binding protein 1 [Homo sapiens]
Length = 1140
Score = 27.7 bits (60), Expect = 9.1
Identities = 14/50 (28%), Positives = 25/50 (50%)
Query: 23 DGLQRLHMLQISYFRDPYHVWYQGNASLGGHLTHVLEGPDTNTTIIQLQP 72
D +Q+LH+ + + P + YQ + G L+ +E DT+ L+P
Sbjct: 705 DEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRP 754
>gi|6912590 pleckstrin homology-like domain, family A, member 3
[Homo sapiens]
Length = 127
Score = 27.7 bits (60), Expect = 9.1
Identities = 19/58 (32%), Positives = 26/58 (44%), Gaps = 4/58 (6%)
Query: 123 EGSRAHVFFEVAVNGSSFVSFR--PERALWQADTQVTSGVVTFTLQQLNAYNRTRYEL 178
E + H++F + G + FR E W A Q+T G+V F QQ R R L
Sbjct: 65 ESTGRHIYFTLVTEGGGEIDFRCPLEDPGWNA--QITLGLVKFKNQQAIQTVRARQSL 120
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.137 0.424
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,164,235
Number of Sequences: 37866
Number of extensions: 389466
Number of successful extensions: 1070
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 1057
Number of HSP's gapped (non-prelim): 23
length of query: 238
length of database: 18,247,518
effective HSP length: 99
effective length of query: 139
effective length of database: 14,498,784
effective search space: 2015330976
effective search space used: 2015330976
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.