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Search of human proteins with 33469924
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|33469924 minichromosome maintenance complex component 8
isoform 2 [Homo sapiens]
(824 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|33469924 minichromosome maintenance complex component 8 isofo... 1636 0.0
gi|19923727 minichromosome maintenance complex component 8 isofo... 1626 0.0
gi|33356547 minichromosome maintenance complex component 2 [Homo... 301 1e-81
gi|33469919 minichromosome maintenance complex component 4 [Homo... 289 8e-78
gi|33469917 minichromosome maintenance complex component 4 [Homo... 289 8e-78
gi|33469968 minichromosome maintenance complex component 7 isofo... 255 1e-67
gi|7427519 minichromosome maintenance complex component 6 [Homo ... 253 4e-67
gi|23510448 minichromosome maintenance complex component 5 [Homo... 247 3e-65
gi|6631095 minichromosome maintenance complex component 3 [Homo ... 236 5e-62
gi|33469922 minichromosome maintenance complex component 7 isofo... 230 4e-60
gi|23397546 minichromosome maintenance complex component 9 [Homo... 121 2e-27
gi|209954823 minichromosome maintenance complex component-like i... 37 0.057
gi|209954821 minichromosome maintenance complex component-like i... 36 0.17
gi|90265805 phospholipase C, delta 1 isoform 2 [Homo sapiens] 35 0.37
gi|195972883 phospholipase C, delta 1 isoform 1 [Homo sapiens] 35 0.37
gi|224831253 optic atrophy 1 isoform 8 [Homo sapiens] 32 3.1
gi|224831251 optic atrophy 1 isoform 7 [Homo sapiens] 32 3.1
gi|18860841 optic atrophy 1 isoform 6 [Homo sapiens] 32 3.1
gi|224831248 optic atrophy 1 isoform 5 [Homo sapiens] 32 3.1
gi|18860835 optic atrophy 1 isoform 4 [Homo sapiens] 32 3.1
gi|18860833 optic atrophy 1 isoform 3 [Homo sapiens] 32 3.1
gi|18860831 optic atrophy 1 isoform 2 [Homo sapiens] 32 3.1
gi|224831243 optic atrophy 1 isoform 1 [Homo sapiens] 32 3.1
gi|30061565 La ribonucleoprotein domain family member 2 isoform ... 32 3.1
gi|30061569 La ribonucleoprotein domain family member 2 isoform ... 32 3.1
gi|30061567 La ribonucleoprotein domain family member 2 isoform ... 32 3.1
gi|114155133 dynein, axonemal, heavy chain 9 isoform 2 [Homo sap... 32 3.1
gi|7242140 ClpX caseinolytic protease X homolog [Homo sapiens] 31 4.1
gi|40255119 RAS and EF-hand domain containing [Homo sapiens] 31 4.1
gi|11141871 J domain containing protein 1 isoform a [Homo sapiens] 31 4.1
>gi|33469924 minichromosome maintenance complex component 8 isoform
2 [Homo sapiens]
Length = 824
Score = 1636 bits (4237), Expect = 0.0
Identities = 824/824 (100%), Positives = 824/824 (100%)
Query: 1 MNGEYRGRGFGRGRFQSWKRGRGGGNFSGKWREREHRPDLSKTTGKRTSEQTPQFLLSTK 60
MNGEYRGRGFGRGRFQSWKRGRGGGNFSGKWREREHRPDLSKTTGKRTSEQTPQFLLSTK
Sbjct: 1 MNGEYRGRGFGRGRFQSWKRGRGGGNFSGKWREREHRPDLSKTTGKRTSEQTPQFLLSTK 60
Query: 61 TPQSMQSTLDRFIPYKGWKLYFSEVYSDSSPLIEKIQAFEKFFTRHIDLYDKDEIERKGS 120
TPQSMQSTLDRFIPYKGWKLYFSEVYSDSSPLIEKIQAFEKFFTRHIDLYDKDEIERKGS
Sbjct: 61 TPQSMQSTLDRFIPYKGWKLYFSEVYSDSSPLIEKIQAFEKFFTRHIDLYDKDEIERKGS 120
Query: 121 ILVDFKELTEGGEVTNLIPDIATELRDAPEKTLACMGLAIHQVLTKDLERHAAELQAQEG 180
ILVDFKELTEGGEVTNLIPDIATELRDAPEKTLACMGLAIHQVLTKDLERHAAELQAQEG
Sbjct: 121 ILVDFKELTEGGEVTNLIPDIATELRDAPEKTLACMGLAIHQVLTKDLERHAAELQAQEG 180
Query: 181 LSNDGETMVNVPHIHARVYNYEPLTQLKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAF 240
LSNDGETMVNVPHIHARVYNYEPLTQLKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAF
Sbjct: 181 LSNDGETMVNVPHIHARVYNYEPLTQLKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAF 240
Query: 241 LCAACGEIQSFPLPDGKYSLPTKCPVPVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDD 300
LCAACGEIQSFPLPDGKYSLPTKCPVPVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDD
Sbjct: 241 LCAACGEIQSFPLPDGKYSLPTKCPVPVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDD 300
Query: 301 QREAGRIPRTIECELVHDLVDSCVPGDTVTITGIVKVSNAEEANSISNSKGQKTKSSEDG 360
QREAGRIPRTIECELVHDLVDSCVPGDTVTITGIVKVSNAEEANSISNSKGQKTKSSEDG
Sbjct: 301 QREAGRIPRTIECELVHDLVDSCVPGDTVTITGIVKVSNAEEANSISNSKGQKTKSSEDG 360
Query: 361 CKHGMLMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVIFGHELVKAGLALALFGGSQKYA 420
CKHGMLMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVIFGHELVKAGLALALFGGSQKYA
Sbjct: 361 CKHGMLMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVIFGHELVKAGLALALFGGSQKYA 420
Query: 421 DDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTTSGLTVTLSKDSS 480
DDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTTSGLTVTLSKDSS
Sbjct: 421 DDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTTSGLTVTLSKDSS 480
Query: 481 SGDFALEAGALVLGDQGICGIDEFDKMGNQHQALLEAMEQQSISLAKAGVVCSLPARTSI 540
SGDFALEAGALVLGDQGICGIDEFDKMGNQHQALLEAMEQQSISLAKAGVVCSLPARTSI
Sbjct: 481 SGDFALEAGALVLGDQGICGIDEFDKMGNQHQALLEAMEQQSISLAKAGVVCSLPARTSI 540
Query: 541 IAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFILLDTPNEHHDHLLSEHVIAIRAGK 600
IAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFILLDTPNEHHDHLLSEHVIAIRAGK
Sbjct: 541 IAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFILLDTPNEHHDHLLSEHVIAIRAGK 600
Query: 601 QRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVVPGETIDPIPHQLLRKYIGYARQY 660
QRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVVPGETIDPIPHQLLRKYIGYARQY
Sbjct: 601 QRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVVPGETIDPIPHQLLRKYIGYARQY 660
Query: 661 VYPRLSTEAARVLQDFYLELRKQSQRLNSSPITTRQLESLIRLTEARARLELREEATKED 720
VYPRLSTEAARVLQDFYLELRKQSQRLNSSPITTRQLESLIRLTEARARLELREEATKED
Sbjct: 661 VYPRLSTEAARVLQDFYLELRKQSQRLNSSPITTRQLESLIRLTEARARLELREEATKED 720
Query: 721 AEDIVEIMKYSMLGTYSDEFGNLDFERSQHGSGMSNRSTAKRFISALNNVAERTYNNIFQ 780
AEDIVEIMKYSMLGTYSDEFGNLDFERSQHGSGMSNRSTAKRFISALNNVAERTYNNIFQ
Sbjct: 721 AEDIVEIMKYSMLGTYSDEFGNLDFERSQHGSGMSNRSTAKRFISALNNVAERTYNNIFQ 780
Query: 781 FHQLRQIAKELNIQVADFENFIGSLNDQGYLLKKGPKVYQLQTM 824
FHQLRQIAKELNIQVADFENFIGSLNDQGYLLKKGPKVYQLQTM
Sbjct: 781 FHQLRQIAKELNIQVADFENFIGSLNDQGYLLKKGPKVYQLQTM 824
>gi|19923727 minichromosome maintenance complex component 8 isoform
1 [Homo sapiens]
Length = 840
Score = 1626 bits (4210), Expect = 0.0
Identities = 824/840 (98%), Positives = 824/840 (98%), Gaps = 16/840 (1%)
Query: 1 MNGEYRGRGFGRGRFQSWKRGRGGGNFSGKWREREHRPDLSKTTGKRTSEQTPQFLLSTK 60
MNGEYRGRGFGRGRFQSWKRGRGGGNFSGKWREREHRPDLSKTTGKRTSEQTPQFLLSTK
Sbjct: 1 MNGEYRGRGFGRGRFQSWKRGRGGGNFSGKWREREHRPDLSKTTGKRTSEQTPQFLLSTK 60
Query: 61 TPQSMQSTLDRFIPYKGWKLYFSEVYSDSSPLIEKIQAFEKFFTRHIDLYDKDEIERKGS 120
TPQSMQSTLDRFIPYKGWKLYFSEVYSDSSPLIEKIQAFEKFFTRHIDLYDKDEIERKGS
Sbjct: 61 TPQSMQSTLDRFIPYKGWKLYFSEVYSDSSPLIEKIQAFEKFFTRHIDLYDKDEIERKGS 120
Query: 121 ILVDFKELTEGGEVTNLIPDIATELRDAPEKTLACMGLAIHQVLTKDLERHAAELQAQEG 180
ILVDFKELTEGGEVTNLIPDIATELRDAPEKTLACMGLAIHQVLTKDLERHAAELQAQEG
Sbjct: 121 ILVDFKELTEGGEVTNLIPDIATELRDAPEKTLACMGLAIHQVLTKDLERHAAELQAQEG 180
Query: 181 LSNDGETMVNVPHIHARVYNYEPLTQLKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAF 240
LSNDGETMVNVPHIHARVYNYEPLTQLKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAF
Sbjct: 181 LSNDGETMVNVPHIHARVYNYEPLTQLKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAF 240
Query: 241 LCAACGEIQSFPLPDGKYSLPTKCPVPVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDD 300
LCAACGEIQSFPLPDGKYSLPTKCPVPVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDD
Sbjct: 241 LCAACGEIQSFPLPDGKYSLPTKCPVPVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDD 300
Query: 301 QREAGRIPRTIECELVHDLVDSCVPGDTVTITGIVKVSNAEE----------------AN 344
QREAGRIPRTIECELVHDLVDSCVPGDTVTITGIVKVSNAEE AN
Sbjct: 301 QREAGRIPRTIECELVHDLVDSCVPGDTVTITGIVKVSNAEEGSRNKNDKCMFLLYIEAN 360
Query: 345 SISNSKGQKTKSSEDGCKHGMLMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVIFGHELV 404
SISNSKGQKTKSSEDGCKHGMLMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVIFGHELV
Sbjct: 361 SISNSKGQKTKSSEDGCKHGMLMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVIFGHELV 420
Query: 405 KAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGN 464
KAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGN
Sbjct: 421 KAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGN 480
Query: 465 TTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQALLEAMEQQSIS 524
TTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQALLEAMEQQSIS
Sbjct: 481 TTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQALLEAMEQQSIS 540
Query: 525 LAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFILLDTPNEH 584
LAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFILLDTPNEH
Sbjct: 541 LAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFILLDTPNEH 600
Query: 585 HDHLLSEHVIAIRAGKQRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVVPGETIDP 644
HDHLLSEHVIAIRAGKQRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVVPGETIDP
Sbjct: 601 HDHLLSEHVIAIRAGKQRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVVPGETIDP 660
Query: 645 IPHQLLRKYIGYARQYVYPRLSTEAARVLQDFYLELRKQSQRLNSSPITTRQLESLIRLT 704
IPHQLLRKYIGYARQYVYPRLSTEAARVLQDFYLELRKQSQRLNSSPITTRQLESLIRLT
Sbjct: 661 IPHQLLRKYIGYARQYVYPRLSTEAARVLQDFYLELRKQSQRLNSSPITTRQLESLIRLT 720
Query: 705 EARARLELREEATKEDAEDIVEIMKYSMLGTYSDEFGNLDFERSQHGSGMSNRSTAKRFI 764
EARARLELREEATKEDAEDIVEIMKYSMLGTYSDEFGNLDFERSQHGSGMSNRSTAKRFI
Sbjct: 721 EARARLELREEATKEDAEDIVEIMKYSMLGTYSDEFGNLDFERSQHGSGMSNRSTAKRFI 780
Query: 765 SALNNVAERTYNNIFQFHQLRQIAKELNIQVADFENFIGSLNDQGYLLKKGPKVYQLQTM 824
SALNNVAERTYNNIFQFHQLRQIAKELNIQVADFENFIGSLNDQGYLLKKGPKVYQLQTM
Sbjct: 781 SALNNVAERTYNNIFQFHQLRQIAKELNIQVADFENFIGSLNDQGYLLKKGPKVYQLQTM 840
>gi|33356547 minichromosome maintenance complex component 2 [Homo
sapiens]
Length = 904
Score = 301 bits (772), Expect = 1e-81
Identities = 222/751 (29%), Positives = 367/751 (48%), Gaps = 92/751 (12%)
Query: 7 GRGFGRGRFQSWKRGRGGGNFSGKWREREHRPDLSKTTGKRTSEQTPQFLLSTKTPQSMQ 66
GRG GR R G E E RP + +R +E + + M
Sbjct: 125 GRGLGRMR---------RGLLYDSDEEDEERPARKRRQVERATEDGEE-------DEEMI 168
Query: 67 STLDRFIPYKGWKLYFSEVYSDSSPLIEKIQAFEKFFTRHIDLYD----KDEI-----ER 117
+++ KG + E S + P +E F+ F H+D + K+ I E
Sbjct: 169 ESIENLEDLKGHSV--REWVSMAGPRLEIHHRFKNFLRTHVDSHGHNVFKERISDMCKEN 226
Query: 118 KGSILVDFKELTEGGEVTNLIPDIATELRDAPEKTLACMGLAIHQVLTKDLERHAAELQA 177
+ S++V++++L V +A L +AP + L A +V+ ++
Sbjct: 227 RESLVVNYEDLAAREHV------LAYFLPEAPAELLQIFDEAALEVVLAMYPKY------ 274
Query: 178 QEGLSNDGETMVNVPHIHARVYNYEPLTQLKNVRANYYGKYIALRGTVVRVSNIKPLCTK 237
+ ++N HIH R+ + + +L+++R + + I G V + + P +
Sbjct: 275 -DRITN---------HIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLSM 324
Query: 238 MAFLCAACGEIQS-FPLPDGKYSLPTKCPVPVCRGRSFTALRSSPLTVTMDWQSIKIQEL 296
+ + C C + F + P CP G + T+ ++Q I+IQE
Sbjct: 325 VKYNCNKCNFVLGPFCQSQNQEVKPGSCPECQSAGPFEVNMEE---TIYQNYQRIRIQE- 380
Query: 297 MSDDQREAGRIPRTIECELVHDLVDSCVPGDTVTITGIVKVSNAEEANS----------- 345
S + AGR+PR+ + L+ DLVDSC PGD + +TGI + N+
Sbjct: 381 -SPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSLNTANGFPVFATVI 439
Query: 346 ISNSKGQKTKSSEDGCKHGMLMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVIFGHELVK 405
++N +K G E + +D+ I + ++ + + I S+ P I+GHE +K
Sbjct: 440 LANHVAKKDNKVAVG-------ELTDEDVKMITSLSKDQQIGEKIFASIAPSIYGHEDIK 492
Query: 406 AGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGNT 465
GLALALFGG K K+++ RGD ++L+ GDPG KSQ L+ V+ R ++ G
Sbjct: 493 RGLALALFGGEPKNPGGKHKV--RGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQG 550
Query: 466 TTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQALL-EAMEQQSIS 524
+ GLT + + S ++ LEAGALVL D+G+C IDEFDKM +Q + + EAMEQQSIS
Sbjct: 551 ASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSIS 610
Query: 525 LAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFILLDTPNEH 584
++KAG+V SL AR ++IAAANP+GG Y+ + T SEN+ + ++SRFD++ ++ DT +
Sbjct: 611 ISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPV 670
Query: 585 HDHLLSEHVIAIRAGKQRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVVPGETIDP 644
D +L+ V+ + + SN + + + G ++P
Sbjct: 671 QDEMLARFVVG--------------SHVRHHPSNKEEEGLANGSAAEPAMPNTYG--VEP 714
Query: 645 IPHQLLRKYIGYARQYVYPRLSTEAARVLQDFYLELRKQSQRLNSSPITTRQLESLIRLT 704
+P ++L+KYI YA++ V+P+L+ + Y +LRK+S S PIT R +ES+IR+
Sbjct: 715 LPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGSIPITVRHIESMIRMA 774
Query: 705 EARARLELREEATKEDAEDIVEIMKYSMLGT 735
EA AR+ LR+ ++D + +M S + T
Sbjct: 775 EAHARIHLRDYVIEDDVNMAIRVMLESFIDT 805
>gi|33469919 minichromosome maintenance complex component 4 [Homo
sapiens]
Length = 863
Score = 289 bits (739), Expect = 8e-78
Identities = 203/647 (31%), Positives = 316/647 (48%), Gaps = 66/647 (10%)
Query: 194 IHARVYNYEPLTQLKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAFLCAACGEIQSFPL 253
I R +N ++N+ + I + G V+R S + P + F C C +
Sbjct: 258 IQVRPFNALKTKNMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVCAHTTRVEM 317
Query: 254 PDGKYSLPTKCPVPVCRGRSFTALRSSPL---TVTMDWQSIKIQELMSDDQREAGRIPRT 310
G+ + P+ C GR T + + ++ D Q IK+QE S + AG+ P T
Sbjct: 318 DRGRIAEPSVC------GRCHTTHSMALIHNRSLFSDKQMIKLQE--SPEDMPAGQTPHT 369
Query: 311 IECELVHDLVDSCVPGDTVTITGIVKVSNAEEANSISNSKG-QKT-------KSSEDGCK 362
+ +DLVD PGD V +TGI + +SN K KT + ++
Sbjct: 370 VILFAHNDLVDKVQPGDRVNVTGIYRAVPIRVNPRVSNVKSVYKTHIDVIHYRKTDAKRL 429
Query: 363 HGMLME-----FSLKDLYAIQEIQAEENLFKLIVNSLCPVIFGHELVKAGLALALFGGSQ 417
HG+ E FS K + ++E+ + ++++ + ++L P I+ HE +K G+ L LFGG++
Sbjct: 430 HGLDEEAEQKLFSEKRVELLKELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFGGTR 489
Query: 418 KYADDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTTSGLTVTLSK 477
K R R + +IL+ GDPG KSQ+LQ N+ PRG Y G ++ GLT + K
Sbjct: 490 KDFSHTGRGKFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMK 549
Query: 478 DSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQALL-EAMEQQSISLAKAGVVCSLPA 536
D + L+ GALVL D GIC IDEFDKM +++L E MEQQ++S+AKAG++C L A
Sbjct: 550 DPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNA 609
Query: 537 RTSIIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFILLDTPNEHHDHLLSEHVIAI 596
RTS++AAANP+ +N KT EN+++ LLSRFDL+F+LLD +E +D L+ H++A
Sbjct: 610 RTSVLAAANPIESQWNPKKTTIENIQLPHTLLSRFDLIFLLLDPQDEAYDRRLAHHLVA- 668
Query: 597 RAGKQRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVVPGETIDPIPHQLLRKYIGY 656
L SE+ E L + +L+ YI Y
Sbjct: 669 -------------------------LYYQSEEQAEEEL----------LDMAVLKDYIAY 693
Query: 657 ARQYVYPRLSTEAARVLQDFYLELRKQSQRLNSSPITTRQLESLIRLTEARARLELREEA 716
A + PRLS EA++ L + Y+++RK RQLESLIRL EA A++ L +
Sbjct: 694 AHSTIMPRLSEEASQALIEAYVDMRKIGSSRGMVSAYPRQLESLIRLAEAHAKVRLSNKV 753
Query: 717 TKEDAEDIVEIMKYSMLGTYSD-EFGNLDFERSQHGSGMSNRSTAKRFISALNN-VAERT 774
D E+ + + ++ + +D G +D G ++R + AL + +
Sbjct: 754 EAIDVEEAKRLHREALKQSATDPRTGIVDISILTTGMSATSRKRKEELAEALKKLILSKG 813
Query: 775 YNNIFQFHQL-RQIAKELNIQVAD--FENFIGSLNDQGYLLKKGPKV 818
++ QL I + +I + FE + +L D +L G V
Sbjct: 814 KTPALKYQQLFEDIRGQSDIAITKDMFEEALRALADDDFLTVTGKTV 860
>gi|33469917 minichromosome maintenance complex component 4 [Homo
sapiens]
Length = 863
Score = 289 bits (739), Expect = 8e-78
Identities = 203/647 (31%), Positives = 316/647 (48%), Gaps = 66/647 (10%)
Query: 194 IHARVYNYEPLTQLKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAFLCAACGEIQSFPL 253
I R +N ++N+ + I + G V+R S + P + F C C +
Sbjct: 258 IQVRPFNALKTKNMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVCAHTTRVEM 317
Query: 254 PDGKYSLPTKCPVPVCRGRSFTALRSSPL---TVTMDWQSIKIQELMSDDQREAGRIPRT 310
G+ + P+ C GR T + + ++ D Q IK+QE S + AG+ P T
Sbjct: 318 DRGRIAEPSVC------GRCHTTHSMALIHNRSLFSDKQMIKLQE--SPEDMPAGQTPHT 369
Query: 311 IECELVHDLVDSCVPGDTVTITGIVKVSNAEEANSISNSKG-QKT-------KSSEDGCK 362
+ +DLVD PGD V +TGI + +SN K KT + ++
Sbjct: 370 VILFAHNDLVDKVQPGDRVNVTGIYRAVPIRVNPRVSNVKSVYKTHIDVIHYRKTDAKRL 429
Query: 363 HGMLME-----FSLKDLYAIQEIQAEENLFKLIVNSLCPVIFGHELVKAGLALALFGGSQ 417
HG+ E FS K + ++E+ + ++++ + ++L P I+ HE +K G+ L LFGG++
Sbjct: 430 HGLDEEAEQKLFSEKRVELLKELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFGGTR 489
Query: 418 KYADDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTTSGLTVTLSK 477
K R R + +IL+ GDPG KSQ+LQ N+ PRG Y G ++ GLT + K
Sbjct: 490 KDFSHTGRGKFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMK 549
Query: 478 DSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQALL-EAMEQQSISLAKAGVVCSLPA 536
D + L+ GALVL D GIC IDEFDKM +++L E MEQQ++S+AKAG++C L A
Sbjct: 550 DPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNA 609
Query: 537 RTSIIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFILLDTPNEHHDHLLSEHVIAI 596
RTS++AAANP+ +N KT EN+++ LLSRFDL+F+LLD +E +D L+ H++A
Sbjct: 610 RTSVLAAANPIESQWNPKKTTIENIQLPHTLLSRFDLIFLLLDPQDEAYDRRLAHHLVA- 668
Query: 597 RAGKQRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVVPGETIDPIPHQLLRKYIGY 656
L SE+ E L + +L+ YI Y
Sbjct: 669 -------------------------LYYQSEEQAEEEL----------LDMAVLKDYIAY 693
Query: 657 ARQYVYPRLSTEAARVLQDFYLELRKQSQRLNSSPITTRQLESLIRLTEARARLELREEA 716
A + PRLS EA++ L + Y+++RK RQLESLIRL EA A++ L +
Sbjct: 694 AHSTIMPRLSEEASQALIEAYVDMRKIGSSRGMVSAYPRQLESLIRLAEAHAKVRLSNKV 753
Query: 717 TKEDAEDIVEIMKYSMLGTYSD-EFGNLDFERSQHGSGMSNRSTAKRFISALNN-VAERT 774
D E+ + + ++ + +D G +D G ++R + AL + +
Sbjct: 754 EAIDVEEAKRLHREALKQSATDPRTGIVDISILTTGMSATSRKRKEELAEALKKLILSKG 813
Query: 775 YNNIFQFHQL-RQIAKELNIQVAD--FENFIGSLNDQGYLLKKGPKV 818
++ QL I + +I + FE + +L D +L G V
Sbjct: 814 KTPALKYQQLFEDIRGQSDIAITKDMFEEALRALADDDFLTVTGKTV 860
>gi|33469968 minichromosome maintenance complex component 7 isoform
1 [Homo sapiens]
Length = 719
Score = 255 bits (652), Expect = 1e-67
Identities = 173/543 (31%), Positives = 272/543 (50%), Gaps = 69/543 (12%)
Query: 207 LKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAFLCAACGEIQSFPLPDGKYSLPTKCPV 266
++ VRA+ GK + +RG V RVS +KP + C CG P+ + CP
Sbjct: 149 IREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCDQCGAETYQPIQSPTFMPLIMCPS 208
Query: 267 PVCR-----GRSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELVHDLVD 321
C+ GR + R S + +Q +K+QE DQ G IPR+I + +
Sbjct: 209 QECQTNRSGGRLYLQTRGSRF---IKFQEMKMQE--HSDQVPVGNIPRSITVLVEGENTR 263
Query: 322 SCVPGDTVTITGI-----------VKVSNAEEANSISNSKGQKTKSSEDGCKHGMLMEFS 370
PGD V++TGI V E ++ + KS +D G L
Sbjct: 264 IAQPGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEAHRIVKMNKSEDDESGAGELTREE 323
Query: 371 LKDLYAIQEIQAEENLFKLIVNSLCPVIFGHELVKAGLALALFGGSQKYADDKNRIPIRG 430
L+ + AEE+ ++ + S+ P I+GHE VK L L L GG + + IRG
Sbjct: 324 LRQI-------AEEDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQ---SPRGMKIRG 373
Query: 431 DPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTTSGLTVTLSKDSSSGDFALEAGA 490
+ +I ++GDPG+ KSQ+L +APR Y G ++ GLT + +DS SG+ LE GA
Sbjct: 374 NINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGA 433
Query: 491 LVLGDQGICGIDEFDKMGN-QHQALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPVGG 549
LVL DQG+C IDEFDKM A+ E MEQQ+IS+AKAG++ +L AR SI+AAANP G
Sbjct: 434 LVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYG 493
Query: 550 HYNKAKTVSENLKMGSALLSRFDLVFILLDTPNEHHDHLLSEHVIAIRAGKQRTISSATV 609
YN +++ +N+++ +ALLSRFDL++++ D P+ +D L++H+ + ++
Sbjct: 494 RYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQ------- 546
Query: 610 ARMNSQDSNTSVLEVVSEKPLSERLKVVPGETIDPIPHQLLRKYIGYARQYVYPRLSTEA 669
P +P+ +L+R+YI R+ P +
Sbjct: 547 ----------------------------PPSQFEPLDMKLMRRYIAMCRE-KQPMVPESL 577
Query: 670 ARVLQDFYLELRKQSQRLNSSPITT-RQLESLIRLTEARARLELREEATKEDAEDIVEIM 728
A + Y+E+R+++ + T+ R L +++RL+ A ARL + + KED + + +M
Sbjct: 578 ADYITAAYVEMRREAWASKDATYTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLM 637
Query: 729 KYS 731
+ S
Sbjct: 638 EMS 640
>gi|7427519 minichromosome maintenance complex component 6 [Homo
sapiens]
Length = 821
Score = 253 bits (647), Expect = 4e-67
Identities = 179/623 (28%), Positives = 302/623 (48%), Gaps = 99/623 (15%)
Query: 206 QLKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAFLCAACGEIQSFPLPDGKYSLPTKCP 265
+++ + ++ G + G VVR + P FLC C + KY+ P C
Sbjct: 122 KIRELTSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVIRDVEQQFKYTQPNICR 181
Query: 266 VPVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELVHDLVDSCVP 325
PVC R L ++ +D+Q ++IQE ++ R G IPR++E L + V+S
Sbjct: 182 NPVCANRRRFLLDTNKSRF-VDFQKVRIQETQAELPR--GSIPRSLEVILRAEAVESAQA 238
Query: 326 GDTVTITGIVKV-----------SNAEEANSISNSKGQKTKS------------------ 356
GD TG + V + AE + +S G +T+
Sbjct: 239 GDKCDFTGTLIVVPDVSKLSTPGARAETNSRVSGVDGYETEGIRGLRALGVRDLSYRLVF 298
Query: 357 ------------------SEDGCKHGMLMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVI 398
E+ + + ++K+ + E+ ++NL+ + SL P I
Sbjct: 299 LACCVAPTNPRFGGKELRDEEQTAESIKNQMTVKEWEKVFEMSQDKNLYHNLCTSLFPTI 358
Query: 399 FGHELVKAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRG 458
G++ VK G+ L LFGG K + + RGD ++ +VGDP KSQ L+ +PR
Sbjct: 359 HGNDEVKRGVLLMLFGGVPKTTGEGTSL--RGDINVCIVGDPSTAKSQFLKHVEEFSPRA 416
Query: 459 VYVCGNTTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQ-ALLEA 517
VY G ++ +GLT + +D S +F +EAGAL+L D G+C IDEFDKM + Q A+ EA
Sbjct: 417 VYTSGKASSAAGLTAAVVRDEESHEFVIEAGALMLADNGVCCIDEFDKMDVRDQVAIHEA 476
Query: 518 MEQQSISLAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFIL 577
MEQQ+IS+ KAGV +L ARTSI+AAANP+ GHY+++K++ +N+ + + ++SRFDL FIL
Sbjct: 477 MEQQTISITKAGVKATLNARTSILAAANPISGHYDRSKSLKQNINLSAPIMSRFDLFFIL 536
Query: 578 LDTPNEHHDHLLSEHVIAIRAGKQRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVV 637
+D NE D+ ++ ++ + + + +I R+ S D
Sbjct: 537 VDECNEVTDYAIARRIVDLHSRIEESID-----RVYSLDD-------------------- 571
Query: 638 PGETIDPIPHQLLRKYIGYARQYVYPRLSTEAARVLQDFYLELRKQ---SQRLNSSPITT 694
+R+Y+ +ARQ+ P++S E+ + + Y LR++ +S IT
Sbjct: 572 ------------IRRYLLFARQF-KPKISKESEDFIVEQYKHLRQRDGSGVTKSSWRITV 618
Query: 695 RQLESLIRLTEARARLELREEATKEDAEDIVEIMKYSMLGTYS-----DEFGNLDFERSQ 749
RQLES+IRL+EA AR+ +E + ++ ++ S++ + D+ + E +
Sbjct: 619 RQLESMIRLSEAMARMHCCDEVQPKHVKEAFRLLNKSIIRVETPDVNLDQEEEIQMEVDE 678
Query: 750 HGSGMSNRSTAKRFISALNNVAE 772
G++ + + ++ +N E
Sbjct: 679 GAGGINGHADSPAPVNGINGYNE 701
>gi|23510448 minichromosome maintenance complex component 5 [Homo
sapiens]
Length = 734
Score = 247 bits (631), Expect = 3e-65
Identities = 178/557 (31%), Positives = 289/557 (51%), Gaps = 70/557 (12%)
Query: 205 TQLKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAFLCAACGE----IQSFPLPDGKYSL 260
+ +++++++ + + G ++ S ++ T+++ C +C I P +G Y+L
Sbjct: 135 SSIRSLKSDMMSHLVKIPGIIIAASAVRAKATRISIQCRSCRNTLTNIAMRPGLEG-YAL 193
Query: 261 PTKCPV-----PVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECEL 315
P KC P C + + V D+Q++K+QEL D G +PR ++
Sbjct: 194 PRKCNTDQAGRPKCPLDPYFIMPDKCKCV--DFQTLKLQEL--PDAVPHGEMPRHMQLYC 249
Query: 316 VHDLVDSCVPGDTVTITGIVKVSNAEEANSISNSK-GQKTKSS----------EDGCKHG 364
L D VPG+ VTI GI + S + G +SS DG
Sbjct: 250 DRYLCDKVVPGNRVTIMGIYSIKKFGLTTSRGRDRVGVGIRSSYIRVLGIQVDTDGSGRS 309
Query: 365 MLMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVIFGHELVKAGLALALFGGSQKYADDKN 424
S ++ + + A N++++I S+ P IFG +K +A LFGGS+K D
Sbjct: 310 FAGAVSPQEEEEFRRLAALPNVYEVISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPDG- 368
Query: 425 RIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTTSGLTVTLSKDSSSGDF 484
+ RGD ++L++GDPG KSQ+L+ +P GVY G ++ +GLT ++ +D SS +F
Sbjct: 369 -LTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVMRDPSSRNF 427
Query: 485 ALEAGALVLGDQGICGIDEFDKMGNQHQ-ALLEAMEQQSISLAKAGVVCSLPARTSIIAA 543
+E GA+VL D G+ IDEFDKM + A+ EAMEQQ+IS+AKAG+ +L +R S++AA
Sbjct: 428 IMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAA 487
Query: 544 ANPVGGHYNKAKTVSENLKMGSALLSRFDLVFILLDTPNEHHDHLLSEHVIAIRAGKQRT 603
AN V G +++ K +N+ +LSRFD++FI+ D NE D +L++HVI +
Sbjct: 488 ANSVFGRWDETKG-EDNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVITLH------ 540
Query: 604 ISSATVARMNSQDSNTSVLEVVSEKPLSERLKVVPGETIDPIPHQLLRKYIGYARQYVYP 663
+S+ T + + V GE I L+K+I Y R P
Sbjct: 541 VSALT------------------------QTQAVEGE----IDLAKLKKFIAYCRVKCGP 572
Query: 664 RLSTEAARVLQDFYLELR-------KQSQRLNSSPITTRQLESLIRLTEARARLELREEA 716
RLS EAA L++ Y+ +R + S R +S PIT RQLE+++R+ EA ++++L+ A
Sbjct: 573 RLSAEAAEKLKNRYIIMRSGARQHERDSDRRSSIPITVRQLEAIVRIAEALSKMKLQPFA 632
Query: 717 TKEDAEDIVEIMKYSML 733
T+ D E+ + + + S L
Sbjct: 633 TEADVEEALRLFQVSTL 649
>gi|6631095 minichromosome maintenance complex component 3 [Homo
sapiens]
Length = 808
Score = 236 bits (603), Expect = 5e-62
Identities = 169/542 (31%), Positives = 278/542 (51%), Gaps = 43/542 (7%)
Query: 219 IALRGTVVRVSNIKPLCTKMAFLCAACGEIQSFPLPD--GKYSLPTKCPVPVCRGRSFTA 276
+ + G V + S ++P + C A + D + P+ P +
Sbjct: 125 VCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTLVAFPSSSVYPTKDEENNPL 184
Query: 277 LRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELVHDLVDSCVPGDTVTITGIVK 336
L+V D Q+I IQE+ ++ AG++PR+++ L DLVD PGD V + G +
Sbjct: 185 ETEYGLSVYKDHQTITIQEM--PEKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVGTYR 242
Query: 337 VSNAEEANSISNS---------KGQKTKSSEDGCKHGMLMEFSLKDLYAIQEIQA--EEN 385
++ S + Q +K ++ FS +D+ I++ ++
Sbjct: 243 CLPGKKGGYTSGTFRTVLIACNVKQMSKDAQPS--------FSAEDIAKIKKFSKTRSKD 294
Query: 386 LFKLIVNSLCPVIFGHELVKAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKS 445
+F + SL P I GH+ VK + L GG ++ D +N IRGD +IL++GDP + KS
Sbjct: 295 IFDQLAKSLAPSIHGHDYVKKAILCLLLGGVER--DLENGSHIRGDINILLIGDPSVAKS 352
Query: 446 QMLQAACNVAPRGVYVCGNTTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFD 505
Q+L+ APR + G ++ GLT ++ D +G+ LEAGA+VL D+G+ IDEFD
Sbjct: 353 QLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFD 412
Query: 506 KMGNQHQ-ALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMG 564
KM + + A+ E MEQ +++AKAG+ L AR S++AAANPV G Y++ KT EN+ +
Sbjct: 413 KMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQ 472
Query: 565 SALLSRFDLVFILLDTPNEHHDHLLSEHVIAI--------RAGKQRTISSATVARMNSQD 616
+LLSRFDL+FI+LD + D +S+HV+ + + G + SA V + + D
Sbjct: 473 DSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHRYRAPGEQDGDAMPLGSA-VDILATDD 531
Query: 617 SNTSVLEVVSEKPLSERLKVVPG---ETIDPIPHQLLRKYIGYARQYVYPRLSTEAARVL 673
N S + + + ++ G + + ++KYI A+ + P L+ E+A +
Sbjct: 532 PNFSQEDQQDTQIYEKHDNLLHGTKKKKEKMVSAAFMKKYIHVAK-IIKPVLTQESATYI 590
Query: 674 QDFYLELRKQ----SQRLNSSPITTRQLESLIRLTEARARLELREEATKEDAEDIVEIMK 729
+ Y LR Q S +SP+T R LE+LIRL A A+ + + +DAE+ VE+++
Sbjct: 591 AEEYSRLRSQDSMSSDTARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQ 650
Query: 730 YS 731
Y+
Sbjct: 651 YA 652
>gi|33469922 minichromosome maintenance complex component 7 isoform
2 [Homo sapiens]
Length = 543
Score = 230 bits (587), Expect = 4e-60
Identities = 160/510 (31%), Positives = 253/510 (49%), Gaps = 69/510 (13%)
Query: 240 FLCAACGEIQSFPLPDGKYSLPTKCPVPVCR-----GRSFTALRSSPLTVTMDWQSIKIQ 294
+ C CG P+ + CP C+ GR + R S + +Q +K+Q
Sbjct: 6 YTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSRF---IKFQEMKMQ 62
Query: 295 ELMSDDQREAGRIPRTIECELVHDLVDSCVPGDTVTITGI-----------VKVSNAEEA 343
E DQ G IPR+I + + PGD V++TGI V E
Sbjct: 63 E--HSDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGFRQVVQGLLSET 120
Query: 344 NSISNSKGQKTKSSEDGCKHGMLMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVIFGHEL 403
++ + KS +D G L L+ + AEE+ ++ + S+ P I+GHE
Sbjct: 121 YLEAHRIVKMNKSEDDESGAGELTREELRQI-------AEEDFYEKLAASIAPEIYGHED 173
Query: 404 VKAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCG 463
VK L L L GG + + IRG+ +I ++GDPG+ KSQ+L +APR Y G
Sbjct: 174 VKKALLLLLVGGVDQ---SPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTG 230
Query: 464 NTTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGN-QHQALLEAMEQQS 522
++ GLT + +DS SG+ LE GALVL DQG+C IDEFDKM A+ E MEQQ+
Sbjct: 231 RGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQT 290
Query: 523 ISLAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFILLDTPN 582
IS+AKAG++ +L AR SI+AAANP G YN +++ +N+++ +ALLSRFDL++++ D P+
Sbjct: 291 ISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPD 350
Query: 583 EHHDHLLSEHVIAIRAGKQRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVVPGETI 642
+D L++H+ + ++ P
Sbjct: 351 RDNDLRLAQHITYVHQHSRQ-----------------------------------PPSQF 375
Query: 643 DPIPHQLLRKYIGYARQYVYPRLSTEAARVLQDFYLELRKQSQRLNSSPITT-RQLESLI 701
+P+ +L+R+YI R+ P + A + Y+E+R+++ + T+ R L +++
Sbjct: 376 EPLDMKLMRRYIAMCRE-KQPMVPESLADYITAAYVEMRREAWASKDATYTSARTLLAIL 434
Query: 702 RLTEARARLELREEATKEDAEDIVEIMKYS 731
RL+ A ARL + + KED + + +M+ S
Sbjct: 435 RLSTALARLRMVDVVEKEDVNEAIRLMEMS 464
>gi|23397546 minichromosome maintenance complex component 9 [Homo
sapiens]
Length = 391
Score = 121 bits (304), Expect = 2e-27
Identities = 98/313 (31%), Positives = 148/313 (47%), Gaps = 56/313 (17%)
Query: 193 HIHARVYNYEPLTQLKNV---RANYYGKYIALRGTVVRVSNIKPLCTKMAFLCAACGEIQ 249
++HAR+ +L + G ++++ GTV+R S +K L + ++C C +
Sbjct: 95 NLHARISGLPVCPELVREHIPKTKDVGHFLSVTGTVIRTSLVKVLEFERDYMCNKCKHVF 154
Query: 250 SFPLPDGKYSL---PTKCP-VPVCRGRSFTALR--SSPLTVTMDWQSIKIQELMSDDQRE 303
+Y P+ CP + C FT L SS T D+Q IKIQE + +
Sbjct: 155 VIKADFEQYYTFCRPSSCPSLESCDSSKFTCLSGLSSSPTRCRDYQEIKIQEQVQ--RLS 212
Query: 304 AGRIPRTIECELVHDLVDSCVPGDTVTITGIV-------------KVSNAEEANSISNSK 350
G IPR+++ L DLVDSC GD +TI GIV +V +AN I +
Sbjct: 213 VGSIPRSMKVILEDDLVDSCKSGDDLTIYGIVMQRWKPFQQDVRCEVEIVLKANYIQVNN 272
Query: 351 GQKTKSSEDGCKHGMLMEFSLKDLYAIQEIQAEENLF------------KLIVNSLCPVI 398
Q + G++M+ +E+Q E F +I+ SLCP +
Sbjct: 273 EQSS---------GIIMD---------EEVQKEFEDFWEYYKSDPFAGRNVILASLCPQV 314
Query: 399 FGHELVKAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRG 458
FG LVK +A+ L GG Q+ D +RG+ H+L+VGDPG GKSQ L+ A + PR
Sbjct: 315 FGMYLVKLAVAMVLAGGIQR--TDATGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRS 372
Query: 459 VYVCGNTTTTSGL 471
V G +T++G+
Sbjct: 373 VLTTGIGSTSAGI 385
>gi|209954823 minichromosome maintenance complex component-like
isoform b [Homo sapiens]
Length = 632
Score = 37.4 bits (85), Expect = 0.057
Identities = 24/75 (32%), Positives = 40/75 (53%), Gaps = 1/75 (1%)
Query: 666 STEAARVLQDFYLELRK-QSQRLNSSPITTRQLESLIRLTEARARLELREEATKEDAEDI 724
S EA R+ +YL R+ ++ + S ++ L+ L+ L+EA ARL LR + KED
Sbjct: 555 SLEAERMTHGYYLASRRIRTGSVCGSKLSASALKYLVFLSEAHARLNLRNKVLKEDVLIA 614
Query: 725 VEIMKYSMLGTYSDE 739
+ + S+ Y +E
Sbjct: 615 ALLFETSLTLKYGNE 629
Score = 30.8 bits (68), Expect = 5.3
Identities = 25/90 (27%), Positives = 47/90 (52%), Gaps = 11/90 (12%)
Query: 434 ILVVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTTSGLTVTLSKDS-SSGDFALEAGALV 492
IL++ L ++L + N+ PRG+ ++ + TLS++ +G +++AG+ +
Sbjct: 346 ILIITSDTLLIDRLLNFSINLVPRGI----RHLVSTEIFPTLSRNKYGTGAVSIQAGSAL 401
Query: 493 LGDQGICGIDEF-----DKMGNQHQALLEA 517
L GIC I + DK+ Q Q +LE+
Sbjct: 402 LAKGGICFIGDLASHKKDKL-EQLQTVLES 430
>gi|209954821 minichromosome maintenance complex component-like
isoform a [Homo sapiens]
Length = 681
Score = 35.8 bits (81), Expect = 0.17
Identities = 21/56 (37%), Positives = 33/56 (58%), Gaps = 1/56 (1%)
Query: 666 STEAARVLQDFYLELRK-QSQRLNSSPITTRQLESLIRLTEARARLELREEATKED 720
S EA R+ +YL R+ ++ + S ++ L+ L+ L+EA ARL LR + KED
Sbjct: 555 SLEAERMTHGYYLASRRIRTGSVCGSKLSASALKYLVFLSEAHARLNLRNKVLKED 610
Score = 30.8 bits (68), Expect = 5.3
Identities = 25/90 (27%), Positives = 47/90 (52%), Gaps = 11/90 (12%)
Query: 434 ILVVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTTSGLTVTLSKDS-SSGDFALEAGALV 492
IL++ L ++L + N+ PRG+ ++ + TLS++ +G +++AG+ +
Sbjct: 346 ILIITSDTLLIDRLLNFSINLVPRGI----RHLVSTEIFPTLSRNKYGTGAVSIQAGSAL 401
Query: 493 LGDQGICGIDEF-----DKMGNQHQALLEA 517
L GIC I + DK+ Q Q +LE+
Sbjct: 402 LAKGGICFIGDLASHKKDKL-EQLQTVLES 430
>gi|90265805 phospholipase C, delta 1 isoform 2 [Homo sapiens]
Length = 756
Score = 34.7 bits (78), Expect = 0.37
Identities = 34/141 (24%), Positives = 63/141 (44%), Gaps = 22/141 (15%)
Query: 673 LQDFYLELRKQSQRLNSSPITTRQLESLIRLTEARARLELREEATKEDAEDIVEIMKYSM 732
LQ+ + ++S+++ +P + QL S+ + E R + R E ++ A D+ E +S+
Sbjct: 44 LQEDCKTIWQESRKVMRTPES--QLFSIEDIQEVR--MGHRTEGLEKFARDVPEDRCFSI 99
Query: 733 LGTYSDEFGNLDF----------------ERSQHGSGMSNRSTAKRFISALNNVAERTYN 776
+ + D+ LD + H M R + +I + A++ +
Sbjct: 100 V--FKDQRNTLDLIAPSPADAQHWVLGLHKIIHHSGSMDQRQKLQHWIHSCLRKADKNKD 157
Query: 777 NIFQFHQLRQIAKELNIQVAD 797
N F +L+ KELNIQV D
Sbjct: 158 NKMSFKELQNFLKELNIQVDD 178
>gi|195972883 phospholipase C, delta 1 isoform 1 [Homo sapiens]
Length = 777
Score = 34.7 bits (78), Expect = 0.37
Identities = 34/141 (24%), Positives = 63/141 (44%), Gaps = 22/141 (15%)
Query: 673 LQDFYLELRKQSQRLNSSPITTRQLESLIRLTEARARLELREEATKEDAEDIVEIMKYSM 732
LQ+ + ++S+++ +P + QL S+ + E R + R E ++ A D+ E +S+
Sbjct: 65 LQEDCKTIWQESRKVMRTPES--QLFSIEDIQEVR--MGHRTEGLEKFARDVPEDRCFSI 120
Query: 733 LGTYSDEFGNLDF----------------ERSQHGSGMSNRSTAKRFISALNNVAERTYN 776
+ + D+ LD + H M R + +I + A++ +
Sbjct: 121 V--FKDQRNTLDLIAPSPADAQHWVLGLHKIIHHSGSMDQRQKLQHWIHSCLRKADKNKD 178
Query: 777 NIFQFHQLRQIAKELNIQVAD 797
N F +L+ KELNIQV D
Sbjct: 179 NKMSFKELQNFLKELNIQVDD 199
>gi|224831253 optic atrophy 1 isoform 8 [Homo sapiens]
Length = 1015
Score = 31.6 bits (70), Expect = 3.1
Identities = 19/48 (39%), Positives = 27/48 (56%), Gaps = 5/48 (10%)
Query: 432 PHILVVGDPGLGKSQMLQ--AACNVAPRGVYVCGNTTTTSGLTVTLSK 477
P ++VVGD GK+ +L+ A + PRG G T S + VTLS+
Sbjct: 344 PRVVVVGDQSAGKTSVLEMIAQARIFPRG---SGEMMTRSPVKVTLSE 388
>gi|224831251 optic atrophy 1 isoform 7 [Homo sapiens]
Length = 997
Score = 31.6 bits (70), Expect = 3.1
Identities = 19/48 (39%), Positives = 27/48 (56%), Gaps = 5/48 (10%)
Query: 432 PHILVVGDPGLGKSQMLQ--AACNVAPRGVYVCGNTTTTSGLTVTLSK 477
P ++VVGD GK+ +L+ A + PRG G T S + VTLS+
Sbjct: 326 PRVVVVGDQSAGKTSVLEMIAQARIFPRG---SGEMMTRSPVKVTLSE 370
>gi|18860841 optic atrophy 1 isoform 6 [Homo sapiens]
Length = 979
Score = 31.6 bits (70), Expect = 3.1
Identities = 19/48 (39%), Positives = 27/48 (56%), Gaps = 5/48 (10%)
Query: 432 PHILVVGDPGLGKSQMLQ--AACNVAPRGVYVCGNTTTTSGLTVTLSK 477
P ++VVGD GK+ +L+ A + PRG G T S + VTLS+
Sbjct: 308 PRVVVVGDQSAGKTSVLEMIAQARIFPRG---SGEMMTRSPVKVTLSE 352
>gi|224831248 optic atrophy 1 isoform 5 [Homo sapiens]
Length = 978
Score = 31.6 bits (70), Expect = 3.1
Identities = 19/48 (39%), Positives = 27/48 (56%), Gaps = 5/48 (10%)
Query: 432 PHILVVGDPGLGKSQMLQ--AACNVAPRGVYVCGNTTTTSGLTVTLSK 477
P ++VVGD GK+ +L+ A + PRG G T S + VTLS+
Sbjct: 307 PRVVVVGDQSAGKTSVLEMIAQARIFPRG---SGEMMTRSPVKVTLSE 351
>gi|18860835 optic atrophy 1 isoform 4 [Homo sapiens]
Length = 961
Score = 31.6 bits (70), Expect = 3.1
Identities = 19/48 (39%), Positives = 27/48 (56%), Gaps = 5/48 (10%)
Query: 432 PHILVVGDPGLGKSQMLQ--AACNVAPRGVYVCGNTTTTSGLTVTLSK 477
P ++VVGD GK+ +L+ A + PRG G T S + VTLS+
Sbjct: 290 PRVVVVGDQSAGKTSVLEMIAQARIFPRG---SGEMMTRSPVKVTLSE 334
>gi|18860833 optic atrophy 1 isoform 3 [Homo sapiens]
Length = 942
Score = 31.6 bits (70), Expect = 3.1
Identities = 19/48 (39%), Positives = 27/48 (56%), Gaps = 5/48 (10%)
Query: 432 PHILVVGDPGLGKSQMLQ--AACNVAPRGVYVCGNTTTTSGLTVTLSK 477
P ++VVGD GK+ +L+ A + PRG G T S + VTLS+
Sbjct: 271 PRVVVVGDQSAGKTSVLEMIAQARIFPRG---SGEMMTRSPVKVTLSE 315
>gi|18860831 optic atrophy 1 isoform 2 [Homo sapiens]
Length = 924
Score = 31.6 bits (70), Expect = 3.1
Identities = 19/48 (39%), Positives = 27/48 (56%), Gaps = 5/48 (10%)
Query: 432 PHILVVGDPGLGKSQMLQ--AACNVAPRGVYVCGNTTTTSGLTVTLSK 477
P ++VVGD GK+ +L+ A + PRG G T S + VTLS+
Sbjct: 253 PRVVVVGDQSAGKTSVLEMIAQARIFPRG---SGEMMTRSPVKVTLSE 297
>gi|224831243 optic atrophy 1 isoform 1 [Homo sapiens]
Length = 960
Score = 31.6 bits (70), Expect = 3.1
Identities = 19/48 (39%), Positives = 27/48 (56%), Gaps = 5/48 (10%)
Query: 432 PHILVVGDPGLGKSQMLQ--AACNVAPRGVYVCGNTTTTSGLTVTLSK 477
P ++VVGD GK+ +L+ A + PRG G T S + VTLS+
Sbjct: 289 PRVVVVGDQSAGKTSVLEMIAQARIFPRG---SGEMMTRSPVKVTLSE 333
>gi|30061565 La ribonucleoprotein domain family member 2 isoform 2
[Homo sapiens]
Length = 522
Score = 31.6 bits (70), Expect = 3.1
Identities = 22/55 (40%), Positives = 27/55 (49%), Gaps = 10/55 (18%)
Query: 1 MNGEYRGRGFGRGRFQSWKRGRGGGN------FSGKWREREHRPDLSKTTGKRTS 49
+ G +RGRG GRGR RGRG GN +S ++E R D T TS
Sbjct: 144 IRGSFRGRGRGRGR----GRGRGRGNPRLNFDYSYGYQEHGERTDQPFQTELNTS 194
>gi|30061569 La ribonucleoprotein domain family member 2 isoform 3
[Homo sapiens]
Length = 358
Score = 31.6 bits (70), Expect = 3.1
Identities = 22/55 (40%), Positives = 27/55 (49%), Gaps = 10/55 (18%)
Query: 1 MNGEYRGRGFGRGRFQSWKRGRGGGN------FSGKWREREHRPDLSKTTGKRTS 49
+ G +RGRG GRGR RGRG GN +S ++E R D T TS
Sbjct: 144 IRGSFRGRGRGRGR----GRGRGRGNPRLNFDYSYGYQEHGERTDQPFQTELNTS 194
>gi|30061567 La ribonucleoprotein domain family member 2 isoform 1
[Homo sapiens]
Length = 914
Score = 31.6 bits (70), Expect = 3.1
Identities = 22/55 (40%), Positives = 27/55 (49%), Gaps = 10/55 (18%)
Query: 1 MNGEYRGRGFGRGRFQSWKRGRGGGN------FSGKWREREHRPDLSKTTGKRTS 49
+ G +RGRG GRGR RGRG GN +S ++E R D T TS
Sbjct: 144 IRGSFRGRGRGRGR----GRGRGRGNPRLNFDYSYGYQEHGERTDQPFQTELNTS 194
>gi|114155133 dynein, axonemal, heavy chain 9 isoform 2 [Homo sapiens]
Length = 4486
Score = 31.6 bits (70), Expect = 3.1
Identities = 25/107 (23%), Positives = 45/107 (42%), Gaps = 11/107 (10%)
Query: 387 FKLIVNSLCPVIFGHELVKAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQ 446
++L+ +L + H V + L LF + ++ NRI + L+VG G GK
Sbjct: 2774 WELLTQTLVEALENHNEVNTVMDLVLFEDAMRHVCHINRILESPRGNALLVGVGGSGKQS 2833
Query: 447 MLQAACNVAPRGVYVCGNTTTTSGLTVTLSKDSSSGDFALEAGALVL 493
+ + A ++ V+ +TL K DF ++ +L L
Sbjct: 2834 LTRLAAFISSMDVF-----------QITLRKGYQIQDFKMDLASLCL 2869
>gi|7242140 ClpX caseinolytic protease X homolog [Homo sapiens]
Length = 633
Score = 31.2 bits (69), Expect = 4.1
Identities = 31/113 (27%), Positives = 47/113 (41%), Gaps = 6/113 (5%)
Query: 433 HILVVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTTSGLTVTLSKDSSSGDFALEAGALV 492
+IL++G G GK+ + Q +C TT T V +S +A V
Sbjct: 288 NILLLGPTGSGKTLLAQTLAKCLDVPFAICDCTTLTQAGYVGEDIESVIAKLLQDANYNV 347
Query: 493 -LGDQGICGIDEFDKMGNQ---HQALLEAME--QQSISLAKAGVVCSLPARTS 539
QGI +DE DK+G+ HQ E QQ + G + ++P + S
Sbjct: 348 EKAQQGIVFLDEVDKIGSVPGIHQLRDVGGEGVQQGLLKLLEGTIVNVPEKNS 400
>gi|40255119 RAS and EF-hand domain containing [Homo sapiens]
Length = 740
Score = 31.2 bits (69), Expect = 4.1
Identities = 32/153 (20%), Positives = 70/153 (45%), Gaps = 11/153 (7%)
Query: 661 VYPRLSTEAARVLQDFYLELRKQSQRLNSSPITTR--QLESLIRLTEAR----ARLELRE 714
V PRL V+++F E+R QS + + I + Q ++ ++L+E R++ E
Sbjct: 158 VEPRLIQPYEHVIKNFIREIRLQSTEMENLAIAVKRAQDKAAMQLSELEEEMDQRIQAAE 217
Query: 715 EATKEDAEDIVEIMKYSMLGTYSDEFGNLD--FERSQHGSGMSNRSTAKRFISALNNVAE 772
T++D + E + Y E G+L ++ + S R + K ++AL +
Sbjct: 218 HKTRKDEKRKAEEALSDLRRQYETEVGDLQVTIKKLRKLEEQSKRVSQKEDVAALK---K 274
Query: 773 RTYNNIFQFHQLRQIAKELNIQVADFENFIGSL 805
+ Y+ + ++++ E +A ++ + +L
Sbjct: 275 QIYDLSMENQKVKKDLLEAQTNIAFLQSELDAL 307
>gi|11141871 J domain containing protein 1 isoform a [Homo sapiens]
Length = 198
Score = 31.2 bits (69), Expect = 4.1
Identities = 18/68 (26%), Positives = 34/68 (50%), Gaps = 2/68 (2%)
Query: 33 EREHRPDLSKTTGKRTSEQTPQFLLSTKTPQSMQSTLDRFIPYKGWKLYFSEVYSDSSPL 92
+RE + + +T ++T ++ P+ L + +PQ+ S+ F GW L F S L
Sbjct: 132 QRERKKEELASTAEKTEQKEPKPLEKSVSPQNSDSS--GFADVNGWHLRFRWSKDAPSEL 189
Query: 93 IEKIQAFE 100
+ K + +E
Sbjct: 190 LRKFRNYE 197
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,312,350
Number of Sequences: 37866
Number of extensions: 1277587
Number of successful extensions: 4113
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 4009
Number of HSP's gapped (non-prelim): 63
length of query: 824
length of database: 18,247,518
effective HSP length: 111
effective length of query: 713
effective length of database: 14,044,392
effective search space: 10013651496
effective search space used: 10013651496
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.