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Search of human proteins with 33391150
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|33391150 nucleoplasmin 2 [Homo sapiens]
(214 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|33391150 nucleoplasmin 2 [Homo sapiens] 421 e-118
gi|6857818 nucleophosmin/nucleoplasmin 3 [Homo sapiens] 92 3e-19
gi|83641870 nucleophosmin 1 isoform 3 [Homo sapiens] 92 3e-19
gi|10835063 nucleophosmin 1 isoform 1 [Homo sapiens] 92 3e-19
gi|40353734 nucleophosmin 1 isoform 2 [Homo sapiens] 85 4e-17
gi|169161779 PREDICTED: similar to nucleophosmin 1 [Homo sapiens] 77 1e-14
gi|169161624 PREDICTED: similar to nucleophosmin 1 [Homo sapiens] 77 1e-14
gi|169162829 PREDICTED: similar to nucleophosmin 1 [Homo sapiens] 77 1e-14
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 55 4e-08
gi|4503257 death-domain associated protein isoform a [Homo sapiens] 53 2e-07
gi|215422388 death-domain associated protein isoform a [Homo sap... 53 2e-07
gi|215422366 death-domain associated protein isoform b [Homo sap... 53 2e-07
gi|55956788 nucleolin [Homo sapiens] 52 4e-07
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 50 1e-06
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 50 1e-06
gi|221219020 NYD-SP11 protein [Homo sapiens] 50 1e-06
gi|55953110 retinoblastoma protein-binding zinc finger protein i... 50 2e-06
gi|20336260 retinoblastoma protein-binding zinc finger protein i... 50 2e-06
gi|20336258 retinoblastoma protein-binding zinc finger protein i... 50 2e-06
gi|48255891 protein kinase C substrate 80K-H isoform 2 [Homo sap... 49 2e-06
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 49 2e-06
gi|8923771 ELG protein isoform b [Homo sapiens] 49 4e-06
gi|166295179 ELG protein isoform a [Homo sapiens] 49 4e-06
gi|17975763 myelin transcription factor 1 [Homo sapiens] 47 9e-06
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 47 9e-06
gi|169210053 PREDICTED: hypothetical protein [Homo sapiens] 46 2e-05
gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo sap... 46 2e-05
gi|4506411 Ran GTPase activating protein 1 [Homo sapiens] 46 2e-05
gi|56711320 hypothetical protein LOC145407 [Homo sapiens] 46 3e-05
gi|118600967 shroom family member 4 [Homo sapiens] 45 4e-05
>gi|33391150 nucleoplasmin 2 [Homo sapiens]
Length = 214
Score = 421 bits (1082), Expect = e-118
Identities = 214/214 (100%), Positives = 214/214 (100%)
Query: 1 MNLSSASSTEEKAVTTVLWGCELSQERRTWTFRPQLEGKQSCRLLLHTICLGEKAKEEMH 60
MNLSSASSTEEKAVTTVLWGCELSQERRTWTFRPQLEGKQSCRLLLHTICLGEKAKEEMH
Sbjct: 1 MNLSSASSTEEKAVTTVLWGCELSQERRTWTFRPQLEGKQSCRLLLHTICLGEKAKEEMH 60
Query: 61 RVEILPPANQEDKKMQPVTIASLQASVLPMVSMVGVQLSPPVTFQLRAGSGPVFLSGQER 120
RVEILPPANQEDKKMQPVTIASLQASVLPMVSMVGVQLSPPVTFQLRAGSGPVFLSGQER
Sbjct: 61 RVEILPPANQEDKKMQPVTIASLQASVLPMVSMVGVQLSPPVTFQLRAGSGPVFLSGQER 120
Query: 121 YEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKK 180
YEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKK
Sbjct: 121 YEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKK 180
Query: 181 LEKEEEEIRASVRDKSPVKKAKATARAKKPGFKK 214
LEKEEEEIRASVRDKSPVKKAKATARAKKPGFKK
Sbjct: 181 LEKEEEEIRASVRDKSPVKKAKATARAKKPGFKK 214
>gi|6857818 nucleophosmin/nucleoplasmin 3 [Homo sapiens]
Length = 178
Score = 92.4 bits (228), Expect = 3e-19
Identities = 53/128 (41%), Positives = 82/128 (64%), Gaps = 4/128 (3%)
Query: 19 WGCELSQERRTWTFRPQLEGKQSCRLLLHTICLGEKAKEEMHRVEILPPANQEDKKMQPV 78
+GCELS R++TF+ + E L L +CL E AK+E + VE++ A D + V
Sbjct: 39 FGCELSGHTRSFTFKVEEEDDAEHVLALTMLCLTEGAKDECNVVEVV--ARNHDHQEIAV 96
Query: 79 TIASLQASVLPMVSMVGVQLSPPVTFQLRAGSGPVFLSGQERYE--ASDLTWEEEEEEEG 136
+A+L+ S PM+S+ QL PPVTF+L++GSGPV ++G+ + ++D++ EE EEEE
Sbjct: 97 PVANLKLSCQPMLSLDDFQLQPPVTFRLKSGSGPVRITGRHQIVTMSNDVSEEESEEEEE 156
Query: 137 EEEEEEEE 144
+ +EEE E
Sbjct: 157 DSDEEEVE 164
>gi|83641870 nucleophosmin 1 isoform 3 [Homo sapiens]
Length = 259
Score = 92.0 bits (227), Expect = 3e-19
Identities = 68/228 (29%), Positives = 109/228 (47%), Gaps = 39/228 (17%)
Query: 18 LWGCELSQERRTWTFRPQLEGKQSCRLLLHTICLGEKAKEEMHRVEILPPANQEDKKMQP 77
L+GCEL ++ + F+ + + +L L T+ LG AK+E+H VE N E ++
Sbjct: 18 LFGCELKADK-DYHFKVDNDENEH-QLSLRTVSLGAGAKDELHIVEA-EAMNYEGSPIK- 73
Query: 78 VTIASLQASVLPMVSMVGVQLSPPVTFQLRAGSGPVFLSGQERYEASDLTWEEEEEEE-- 135
VT+A+L+ SV P VS+ G +++PPV +L+ GSGPV +SGQ + E+EEEE
Sbjct: 74 VTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVEEDAESEDEEEEDV 133
Query: 136 ---------------------------------GEEEEEEEEDDEDEDADISLEEQSPVK 162
+EE+++E+DD+D+ D EE++PVK
Sbjct: 134 KLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDDFDDEEAEEKAPVK 193
Query: 163 QVKRLVPQKQASVAKKKKLEKEEEEIRASVRDKSPVKKAKATARAKKP 210
+ R P K A + + + + S +S K+ K K P
Sbjct: 194 KSIRDTPAKNAQKSNQNGKDSKPSSTPRSKGQESFKKQEKTPKTPKGP 241
>gi|10835063 nucleophosmin 1 isoform 1 [Homo sapiens]
Length = 294
Score = 92.0 bits (227), Expect = 3e-19
Identities = 68/228 (29%), Positives = 109/228 (47%), Gaps = 39/228 (17%)
Query: 18 LWGCELSQERRTWTFRPQLEGKQSCRLLLHTICLGEKAKEEMHRVEILPPANQEDKKMQP 77
L+GCEL ++ + F+ + + +L L T+ LG AK+E+H VE N E ++
Sbjct: 18 LFGCELKADK-DYHFKVDNDENEH-QLSLRTVSLGAGAKDELHIVEA-EAMNYEGSPIK- 73
Query: 78 VTIASLQASVLPMVSMVGVQLSPPVTFQLRAGSGPVFLSGQERYEASDLTWEEEEEEE-- 135
VT+A+L+ SV P VS+ G +++PPV +L+ GSGPV +SGQ + E+EEEE
Sbjct: 74 VTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVEEDAESEDEEEEDV 133
Query: 136 ---------------------------------GEEEEEEEEDDEDEDADISLEEQSPVK 162
+EE+++E+DD+D+ D EE++PVK
Sbjct: 134 KLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDDFDDEEAEEKAPVK 193
Query: 163 QVKRLVPQKQASVAKKKKLEKEEEEIRASVRDKSPVKKAKATARAKKP 210
+ R P K A + + + + S +S K+ K K P
Sbjct: 194 KSIRDTPAKNAQKSNQNGKDSKPSSTPRSKGQESFKKQEKTPKTPKGP 241
>gi|40353734 nucleophosmin 1 isoform 2 [Homo sapiens]
Length = 265
Score = 85.1 bits (209), Expect = 4e-17
Identities = 64/211 (30%), Positives = 106/211 (50%), Gaps = 40/211 (18%)
Query: 18 LWGCELSQERRTWTFRPQLEGKQSCRLLLHTICLGEKAKEEMHRVEILPPANQEDKKMQP 77
L+GCEL ++ + F+ + + +L L T+ LG AK+E+H VE N E ++
Sbjct: 18 LFGCELKADK-DYHFKVDNDENEH-QLSLRTVSLGAGAKDELHIVEA-EAMNYEGSPIK- 73
Query: 78 VTIASLQASVLPMVSMVGVQLSPPVTFQLRAGSGPVFLSGQERYEASDLTWEEEEEEE-- 135
VT+A+L+ SV P VS+ G +++PPV +L+ GSGPV +SGQ + E+EEEE
Sbjct: 74 VTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVEEDAESEDEEEEDV 133
Query: 136 -------------------------GEEEEEEEEDDEDEDA--------DISLEEQSPVK 162
+E+++++D+ED+D D EE++PVK
Sbjct: 134 KLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDDFDDEEAEEKAPVK 193
Query: 163 QVKRLVPQKQASVAKKKKLEKEEEEIRASVR 193
+ + +KQ K K E+I+A ++
Sbjct: 194 KGQESF-KKQEKTPKTPKGPSSVEDIKAKMQ 223
>gi|169161779 PREDICTED: similar to nucleophosmin 1 [Homo sapiens]
Length = 186
Score = 76.6 bits (187), Expect = 1e-14
Identities = 54/177 (30%), Positives = 86/177 (48%), Gaps = 37/177 (20%)
Query: 18 LWGCELSQERRTWTFRPQLEGKQSCRLLLHTICLGEKAKEEMHRVEILPPANQEDKKMQP 77
L+GCEL ++ E + +L L T+ LG K+E+H VE A + K P
Sbjct: 14 LFGCELKADKDDHFKVDNDENEH--QLSLRTVSLGAGTKDELHIVE----AEAMNYKGSP 67
Query: 78 --VTIASLQASVLPMVSMVGVQLSPPVTFQLRAGSGPVFLSGQERYEASDLTWEEEEEEE 135
VT+A+L+ S P VS+ G +++PPV + + GSGPV +SGQ + E+EEEE
Sbjct: 68 IKVTLATLKMSAQPTVSLGGFEITPPVVLRFKCGSGPVHISGQHLVAVEEDAESEDEEEE 127
Query: 136 -----------------------------GEEEEEEEEDDEDEDADISLEEQSPVKQ 163
E+++++++DD+D+ D EE+ PVK+
Sbjct: 128 DVKLLSISGKRSAPGGGSKVPQKKVKLAVDEDDDDDDDDDDDDFDDEEAEEKVPVKK 184
>gi|169161624 PREDICTED: similar to nucleophosmin 1 [Homo sapiens]
Length = 186
Score = 76.6 bits (187), Expect = 1e-14
Identities = 54/177 (30%), Positives = 86/177 (48%), Gaps = 37/177 (20%)
Query: 18 LWGCELSQERRTWTFRPQLEGKQSCRLLLHTICLGEKAKEEMHRVEILPPANQEDKKMQP 77
L+GCEL ++ E + +L L T+ LG K+E+H VE A + K P
Sbjct: 14 LFGCELKADKDDHFKVDNDENEH--QLSLRTVSLGAGTKDELHIVE----AEAMNYKGSP 67
Query: 78 --VTIASLQASVLPMVSMVGVQLSPPVTFQLRAGSGPVFLSGQERYEASDLTWEEEEEEE 135
VT+A+L+ S P VS+ G +++PPV + + GSGPV +SGQ + E+EEEE
Sbjct: 68 IKVTLATLKMSAQPTVSLGGFEITPPVVLRFKCGSGPVHISGQHLVAVEEDAESEDEEEE 127
Query: 136 -----------------------------GEEEEEEEEDDEDEDADISLEEQSPVKQ 163
E+++++++DD+D+ D EE+ PVK+
Sbjct: 128 DVKLLSISGKRSAPGGGSKVPQKKVKLAVDEDDDDDDDDDDDDFDDEEAEEKVPVKK 184
>gi|169162829 PREDICTED: similar to nucleophosmin 1 [Homo sapiens]
Length = 186
Score = 76.6 bits (187), Expect = 1e-14
Identities = 54/177 (30%), Positives = 86/177 (48%), Gaps = 37/177 (20%)
Query: 18 LWGCELSQERRTWTFRPQLEGKQSCRLLLHTICLGEKAKEEMHRVEILPPANQEDKKMQP 77
L+GCEL ++ E + +L L T+ LG K+E+H VE A + K P
Sbjct: 14 LFGCELKADKDDHFKVDNDENEH--QLSLRTVSLGAGTKDELHIVE----AEAMNYKGSP 67
Query: 78 --VTIASLQASVLPMVSMVGVQLSPPVTFQLRAGSGPVFLSGQERYEASDLTWEEEEEEE 135
VT+A+L+ S P VS+ G +++PPV + + GSGPV +SGQ + E+EEEE
Sbjct: 68 IKVTLATLKMSAQPTVSLGGFEITPPVVLRFKCGSGPVHISGQHLVAVEEDAESEDEEEE 127
Query: 136 -----------------------------GEEEEEEEEDDEDEDADISLEEQSPVKQ 163
E+++++++DD+D+ D EE+ PVK+
Sbjct: 128 DVKLLSISGKRSAPGGGSKVPQKKVKLAVDEDDDDDDDDDDDDFDDEEAEEKVPVKK 184
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 55.1 bits (131), Expect = 4e-08
Identities = 38/98 (38%), Positives = 55/98 (56%), Gaps = 8/98 (8%)
Query: 118 QERYEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAK 177
+E EA + EE +EEEG EEEE E +E+ + + E SP K+ K V ++ S A+
Sbjct: 473 EEEKEAKE---EEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAE 529
Query: 178 KKKLEKEE----EEIRASVRDKSPVK-KAKATARAKKP 210
K EKEE E+++ + KSP K +AK+ AK P
Sbjct: 530 AKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSP 567
Score = 36.2 bits (82), Expect = 0.021
Identities = 29/92 (31%), Positives = 45/92 (48%), Gaps = 6/92 (6%)
Query: 122 EASDLTWEEEEEEEGEEEEEEEEDDEDEDAD--ISLEEQSPVKQVKRLVPQKQASVAKKK 179
+A T EE + E + E+EE E A + E +SP K P K + + +K
Sbjct: 637 KAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKS---PVKAEAKSPEK 693
Query: 180 KLEKEEEEIRASVRDKSPVK-KAKATARAKKP 210
+EE ++ + KSPVK +AK+ +AK P
Sbjct: 694 AKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSP 725
Score = 34.7 bits (78), Expect = 0.062
Identities = 41/166 (24%), Positives = 69/166 (41%), Gaps = 19/166 (11%)
Query: 53 EKAKEEMHRVEILPPANQEDKKMQPVTIASLQASVLPMVSMVGVQLSPPVTFQLRAGSGP 112
E+ KEE E +E+ K P A+ + PV + ++ +
Sbjct: 481 EEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEK----------EAKSPVKEEAKSPAEA 530
Query: 113 VFLSGQERYEASDLTWEEEEEEEGEEEEE---EEEDDEDEDADISLEEQSPVKQVKRLVP 169
+E +++ E+ + +EE + E + E E+A E +SP K K
Sbjct: 531 KSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEK-AKSPAK 589
Query: 170 QKQASVAKKKKLEKEE----EEIRASVRDKSPVKK-AKATARAKKP 210
++ S A+ K EK + EE ++ KSPVK+ AK+ A K P
Sbjct: 590 EEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSP 635
Score = 33.5 bits (75), Expect = 0.14
Identities = 24/91 (26%), Positives = 46/91 (50%), Gaps = 9/91 (9%)
Query: 129 EEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLV-------PQKQASVAKKK-- 179
EE++E E+ +E + + + E+A+ + +P K+ V P+++ VAKK+
Sbjct: 875 EEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPD 934
Query: 180 KLEKEEEEIRASVRDKSPVKKAKATARAKKP 210
+ +E A ++ +P KK +AKKP
Sbjct: 935 DAKAKEPSKPAEKKEAAPEKKDTKEEKAKKP 965
Score = 32.3 bits (72), Expect = 0.31
Identities = 25/89 (28%), Positives = 38/89 (42%), Gaps = 9/89 (10%)
Query: 130 EEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKR---------LVPQKQASVAKKKK 180
EEE+ + EE++D + E+A + V++ K V K+ KKK
Sbjct: 843 EEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKK 902
Query: 181 LEKEEEEIRASVRDKSPVKKAKATARAKK 209
+ E+E A V K K + T AKK
Sbjct: 903 VPTPEKEAPAKVEVKEDAKPKEKTEVAKK 931
Score = 32.0 bits (71), Expect = 0.40
Identities = 25/92 (27%), Positives = 43/92 (46%), Gaps = 8/92 (8%)
Query: 119 ERYEASDLTWEEEEEEEGEEEEEEEEDDED-EDADISLEEQSPVKQVKRLVPQKQASVAK 177
++ EA D E+E + E +ED + E +++ +E K + P ++ A
Sbjct: 893 KKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAP 952
Query: 178 KKKLEKEEEEIRASVRDKSPVKKAKATARAKK 209
+KK KEE + K P +K K A+AK+
Sbjct: 953 EKKDTKEE-------KAKKPEEKPKTEAKAKE 977
Score = 31.6 bits (70), Expect = 0.53
Identities = 36/159 (22%), Positives = 62/159 (38%), Gaps = 10/159 (6%)
Query: 53 EKAKEEMHRVEILPPANQEDKKMQPVTIASLQASVLPMVSMVGVQLSPPVTFQLRAGSGP 112
EKAK PP + +K + + A +++ SP P
Sbjct: 548 EKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSP 607
Query: 113 VFLSGQERYEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQ 172
V + EA EE + + E+ + E+A +SP K P+K+
Sbjct: 608 VKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEA------KSPEKAKS---PEKE 658
Query: 173 ASVAKKKKLEKEEEEIRASVRDKSPVK-KAKATARAKKP 210
+ + +K + E ++ + KSPVK +AK+ +AK P
Sbjct: 659 EAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSP 697
Score = 31.6 bits (70), Expect = 0.53
Identities = 30/99 (30%), Positives = 45/99 (45%), Gaps = 19/99 (19%)
Query: 130 EEEEEEGEEEEE-----EEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKKLEKE 184
E+EE + E+ + E + E + + E +SP K K V ++ S K K KE
Sbjct: 656 EKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEK-AKSPVKEEAKSPEKAKSPVKE 714
Query: 185 E------------EEIRASVRDKSPVKK-AKATARAKKP 210
E EE + + KSPVK+ AK+ +AK P
Sbjct: 715 EAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSP 753
Score = 30.4 bits (67), Expect = 1.2
Identities = 26/107 (24%), Positives = 45/107 (42%), Gaps = 9/107 (8%)
Query: 112 PVFLSGQERYEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQ--------SPVKQ 163
PV + +A EE + E + +EE E A ++E+ SPVK+
Sbjct: 683 PVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKE 742
Query: 164 VKRLVPQKQASVAKKKKLEKEEEEIRASVRDKSPVKKAKATARAKKP 210
+ P+K S K K L+ + E + ++++ K +AK P
Sbjct: 743 EAKS-PEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSP 788
Score = 29.6 bits (65), Expect = 2.0
Identities = 26/95 (27%), Positives = 47/95 (49%), Gaps = 21/95 (22%)
Query: 137 EEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKKLEKE-----------E 185
+ EE+ + ++ E + +EEQ+ QV V +++ AK+++ ++E E
Sbjct: 439 KSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGE 498
Query: 186 EEIRASVRD---------KSPVK-KAKATARAKKP 210
EE ++ + KSPVK +AK+ A AK P
Sbjct: 499 EETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSP 533
Score = 29.6 bits (65), Expect = 2.0
Identities = 19/74 (25%), Positives = 37/74 (50%), Gaps = 1/74 (1%)
Query: 129 EEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKKLEKEEEEI 188
+EE ++ E+ + E+ + +SP+K+ + P+K+ ++ K +EEE
Sbjct: 771 KEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAK-APEKEIPKKEEVKSPVKEEEK 829
Query: 189 RASVRDKSPVKKAK 202
V+ K P KKA+
Sbjct: 830 PQEVKVKEPPKKAE 843
Score = 29.3 bits (64), Expect = 2.6
Identities = 25/90 (27%), Positives = 39/90 (43%), Gaps = 10/90 (11%)
Query: 129 EEEEEEEGEEEEEEEEDDEDEDADISLEEQSPV--------KQVKRLVPQKQASVAKKKK 180
+EE + +EEE+ +E E + EE++P K P+K+A K K
Sbjct: 817 KEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEA--PKPKV 874
Query: 181 LEKEEEEIRASVRDKSPVKKAKATARAKKP 210
EK+E + K KK +A + K P
Sbjct: 875 EEKKEPAVEKPKESKVEAKKEEAEDKKKVP 904
Score = 28.1 bits (61), Expect = 5.8
Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 5/85 (5%)
Query: 129 EEEEEEEGEEEEEEEEDDEDEDADISLEEQ--SPVKQVKRLVPQKQASVAKKKKLEKEEE 186
+EE + + + +ED + + +I +E+ SPVK+ ++ PQ+ KK E+E+
Sbjct: 790 KEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEK--PQEVKVKEPPKKAEEEKA 847
Query: 187 EIRASVRDKSPVKKAKATAR-AKKP 210
+K KK +A + A KP
Sbjct: 848 PATPKTEEKKDSKKEEAPKKEAPKP 872
Score = 28.1 bits (61), Expect = 5.8
Identities = 20/75 (26%), Positives = 38/75 (50%), Gaps = 3/75 (4%)
Query: 142 EEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKKLEKEEEEIRASVRDKSPVKKA 201
E+E + E+ ++E+ ++VK P K+A K K EE+ + S ++++P K+A
Sbjct: 811 EKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEK-KDSKKEEAPKKEA 869
Query: 202 --KATARAKKPGFKK 214
K+P +K
Sbjct: 870 PKPKVEEKKEPAVEK 884
Score = 28.1 bits (61), Expect = 5.8
Identities = 21/83 (25%), Positives = 45/83 (54%), Gaps = 9/83 (10%)
Query: 129 EEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKK--KLEKEEE 186
EEE+ + EE+++ ++E + ++++P +V+ +K+ +V K K K+E ++E
Sbjct: 843 EEEKAPATPKTEEKKDSKKEE----APKKEAPKPKVEE---KKEPAVEKPKESKVEAKKE 895
Query: 187 EIRASVRDKSPVKKAKATARAKK 209
E + +P K+A A K+
Sbjct: 896 EAEDKKKVPTPEKEAPAKVEVKE 918
Score = 27.3 bits (59), Expect = 10.0
Identities = 21/73 (28%), Positives = 39/73 (53%), Gaps = 6/73 (8%)
Query: 133 EEEGEEEEEEEEDDEDEDADI-SLEEQSPVKQVKRLVPQKQASVAKKKKLEKEEEEIRAS 191
+EE + E+ + ++ + D+ S E ++P K+ R K AK +EE+++
Sbjct: 741 KEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPV----KEEVKSP 796
Query: 192 VRDKSPVKK-AKA 203
+ KSP+K+ AKA
Sbjct: 797 EKAKSPLKEDAKA 809
>gi|4503257 death-domain associated protein isoform a [Homo sapiens]
Length = 740
Score = 53.1 bits (126), Expect = 2e-07
Identities = 32/93 (34%), Positives = 51/93 (54%), Gaps = 8/93 (8%)
Query: 106 LRAGSGPVFLSGQERYEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVK 165
L +G GP ++ Q AS ++E++EE +EEEEEEE++E+E+A S EE+
Sbjct: 413 LDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEED------ 466
Query: 166 RLVPQKQASVAKKKKLEKEEEEIRASVRDKSPV 198
+ Q Q ++ ++EEE DKSP+
Sbjct: 467 --LEQMQEGQEDDEEEDEEEEAAAGKDGDKSPM 497
Score = 37.7 bits (86), Expect = 0.007
Identities = 22/62 (35%), Positives = 31/62 (50%)
Query: 122 EASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKKL 181
E DL +E +E+ EEE+EEEE +D D S + K L P KQ S + ++
Sbjct: 463 EEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQ 522
Query: 182 EK 183
K
Sbjct: 523 NK 524
>gi|215422388 death-domain associated protein isoform a [Homo
sapiens]
Length = 740
Score = 53.1 bits (126), Expect = 2e-07
Identities = 32/93 (34%), Positives = 51/93 (54%), Gaps = 8/93 (8%)
Query: 106 LRAGSGPVFLSGQERYEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVK 165
L +G GP ++ Q AS ++E++EE +EEEEEEE++E+E+A S EE+
Sbjct: 413 LDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEED------ 466
Query: 166 RLVPQKQASVAKKKKLEKEEEEIRASVRDKSPV 198
+ Q Q ++ ++EEE DKSP+
Sbjct: 467 --LEQMQEGQEDDEEEDEEEEAAAGKDGDKSPM 497
Score = 37.7 bits (86), Expect = 0.007
Identities = 22/62 (35%), Positives = 31/62 (50%)
Query: 122 EASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKKL 181
E DL +E +E+ EEE+EEEE +D D S + K L P KQ S + ++
Sbjct: 463 EEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQ 522
Query: 182 EK 183
K
Sbjct: 523 NK 524
>gi|215422366 death-domain associated protein isoform b [Homo
sapiens]
Length = 752
Score = 53.1 bits (126), Expect = 2e-07
Identities = 32/93 (34%), Positives = 51/93 (54%), Gaps = 8/93 (8%)
Query: 106 LRAGSGPVFLSGQERYEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVK 165
L +G GP ++ Q AS ++E++EE +EEEEEEE++E+E+A S EE+
Sbjct: 425 LDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEED------ 478
Query: 166 RLVPQKQASVAKKKKLEKEEEEIRASVRDKSPV 198
+ Q Q ++ ++EEE DKSP+
Sbjct: 479 --LEQMQEGQEDDEEEDEEEEAAAGKDGDKSPM 509
Score = 37.7 bits (86), Expect = 0.007
Identities = 22/62 (35%), Positives = 31/62 (50%)
Query: 122 EASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKKL 181
E DL +E +E+ EEE+EEEE +D D S + K L P KQ S + ++
Sbjct: 475 EEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQ 534
Query: 182 EK 183
K
Sbjct: 535 NK 536
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 52.0 bits (123), Expect = 4e-07
Identities = 25/69 (36%), Positives = 44/69 (63%), Gaps = 5/69 (7%)
Query: 122 EASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQV-----KRLVPQKQASVA 176
E D ++E+E++ ++E++E++DDED++ + EE+ PVK+ K + QK A A
Sbjct: 234 EDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEA 293
Query: 177 KKKKLEKEE 185
KK+K+E E
Sbjct: 294 KKQKVEGTE 302
Score = 42.0 bits (97), Expect = 4e-04
Identities = 20/60 (33%), Positives = 39/60 (65%), Gaps = 5/60 (8%)
Query: 133 EEEGEEEEEEEEDDEDEDADISLEEQSPV-----KQVKRLVPQKQASVAKKKKLEKEEEE 187
E+E +E++E++EDD+D++ D S EE K+ ++VP K +VA+ + E+++E+
Sbjct: 185 EDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDED 244
Score = 39.7 bits (91), Expect = 0.002
Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 4/79 (5%)
Query: 129 EEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKKLE----KE 184
E+ +EEE ++ EE+EEDDEDED D E + +K + + E E
Sbjct: 143 EDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDE 202
Query: 185 EEEIRASVRDKSPVKKAKA 203
E++ + +P K KA
Sbjct: 203 EDDSEEEAMETTPAKGKKA 221
Score = 35.0 bits (79), Expect = 0.048
Identities = 25/75 (33%), Positives = 34/75 (45%), Gaps = 8/75 (10%)
Query: 134 EEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKKLEKEEEEIRASVR 193
+E EE+ E+EE EDE+ D S EE ++PQK+ A +K V
Sbjct: 22 KEVEEDSEDEEMSEDEEDDSSGEEV--------VIPQKKGKKAAATSAKKVVVSPTKKVA 73
Query: 194 DKSPVKKAKATARAK 208
+P KKA T K
Sbjct: 74 VATPAKKAAVTPGKK 88
Score = 33.5 bits (75), Expect = 0.14
Identities = 29/113 (25%), Positives = 48/113 (42%), Gaps = 25/113 (22%)
Query: 116 SGQERYEASDLTWEEEEEEEGEEEEEEEEDDEDEDA--DISLEEQ--------------- 158
+G+ + + + +E EE E+EE ED+ED+ + ++ + ++
Sbjct: 7 AGKNQGDPKKMAPPPKEVEEDSEDEEMSEDEEDDSSGEEVVIPQKKGKKAAATSAKKVVV 66
Query: 159 SPVKQVKRLVPQKQASVAKKKKLEKEEEEIRASVRDKSPVKKAKATARAKKPG 211
SP K+V P K+A+V KK A+ K V AKA K G
Sbjct: 67 SPTKKVAVATPAKKAAVTPGKK--------AAATPAKKTVTPAKAVTTPGKKG 111
Score = 33.1 bits (74), Expect = 0.18
Identities = 16/59 (27%), Positives = 33/59 (55%), Gaps = 7/59 (11%)
Query: 129 EEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKKLEKEEEE 187
++E+ +E E+++ EE++++DED D +E P K A+ A + E +E++
Sbjct: 141 KKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEP-------AAMKAAAAAPASEDEDDEDD 192
Score = 32.3 bits (72), Expect = 0.31
Identities = 19/80 (23%), Positives = 40/80 (50%), Gaps = 1/80 (1%)
Query: 131 EEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKKLEKEEEEIRA 190
++E+ EEE+++ E+DE++D D +E + AS + + ++++E+
Sbjct: 141 KKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDD 200
Query: 191 SVRDKSPVKKAKAT-ARAKK 209
D S + + T A+ KK
Sbjct: 201 DEEDDSEEEAMETTPAKGKK 220
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 50.4 bits (119), Expect = 1e-06
Identities = 29/81 (35%), Positives = 50/81 (61%), Gaps = 4/81 (4%)
Query: 118 QERYEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSP---VKQVKRLVPQKQAS 174
QE + + + EEEEEE EEEEEEEE++E+E+ D + + +SP K++++++ +
Sbjct: 1393 QEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLR 1452
Query: 175 VAKKKKLEKEEEEIRASVRDK 195
+ L KEEEE R + ++
Sbjct: 1453 TETQNAL-KEEEERRKRIAER 1472
Score = 31.2 bits (69), Expect = 0.69
Identities = 26/83 (31%), Positives = 37/83 (44%), Gaps = 10/83 (12%)
Query: 115 LSGQERYEASDLTWEEEE-EEEGEEEEEEEEDDEDEDADISL------EEQSPVKQVK-- 165
+ G+ R + S E+ + +E G EE E +DE S E Q KQ K
Sbjct: 1328 VKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKR 1387
Query: 166 -RLVPQKQASVAKKKKLEKEEEE 187
R+ Q+ +S K E+EEEE
Sbjct: 1388 RRIKVQEDSSSENKSNSEEEEEE 1410
Score = 29.3 bits (64), Expect = 2.6
Identities = 22/82 (26%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Query: 116 SGQERYEASDLTWEEEEEEEGEEEEEEEEDDE-DEDADISLEEQSPVKQVK-RLVPQKQA 173
S E E T ++ EE G+EE + + + E D D++ S + + + ++ +L
Sbjct: 1254 SDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGE 1313
Query: 174 SVAKKKKLEKEEEEIRASVRDK 195
S +KK KE +E++ R K
Sbjct: 1314 SGEEKKTKPKEHKEVKGRNRRK 1335
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 50.4 bits (119), Expect = 1e-06
Identities = 29/81 (35%), Positives = 50/81 (61%), Gaps = 4/81 (4%)
Query: 118 QERYEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSP---VKQVKRLVPQKQAS 174
QE + + + EEEEEE EEEEEEEE++E+E+ D + + +SP K++++++ +
Sbjct: 1431 QEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLR 1490
Query: 175 VAKKKKLEKEEEEIRASVRDK 195
+ L KEEEE R + ++
Sbjct: 1491 TETQNAL-KEEEERRKRIAER 1510
Score = 31.2 bits (69), Expect = 0.69
Identities = 26/83 (31%), Positives = 37/83 (44%), Gaps = 10/83 (12%)
Query: 115 LSGQERYEASDLTWEEEE-EEEGEEEEEEEEDDEDEDADISL------EEQSPVKQVK-- 165
+ G+ R + S E+ + +E G EE E +DE S E Q KQ K
Sbjct: 1366 VKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKR 1425
Query: 166 -RLVPQKQASVAKKKKLEKEEEE 187
R+ Q+ +S K E+EEEE
Sbjct: 1426 RRIKVQEDSSSENKSNSEEEEEE 1448
Score = 29.3 bits (64), Expect = 2.6
Identities = 22/82 (26%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Query: 116 SGQERYEASDLTWEEEEEEEGEEEEEEEEDDE-DEDADISLEEQSPVKQVK-RLVPQKQA 173
S E E T ++ EE G+EE + + + E D D++ S + + + ++ +L
Sbjct: 1292 SDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGE 1351
Query: 174 SVAKKKKLEKEEEEIRASVRDK 195
S +KK KE +E++ R K
Sbjct: 1352 SGEEKKTKPKEHKEVKGRNRRK 1373
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 50.1 bits (118), Expect = 1e-06
Identities = 28/71 (39%), Positives = 41/71 (57%), Gaps = 5/71 (7%)
Query: 119 ERYEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKK 178
+ E + EEEEE EEEE EEE+ +E+ + EE+ KQV +K+ KK
Sbjct: 2235 DELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQV-----EKEEEEKKK 2289
Query: 179 KKLEKEEEEIR 189
KK EK++EE++
Sbjct: 2290 KKKEKKKEEVQ 2300
Score = 45.8 bits (107), Expect = 3e-05
Identities = 28/82 (34%), Positives = 46/82 (56%), Gaps = 4/82 (4%)
Query: 115 LSGQERYEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQAS 174
LS +E E EEEE EE E EEEEE E+E+ + E+ ++ K+ +K+
Sbjct: 2243 LSSEEEEERE----EEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEE 2298
Query: 175 VAKKKKLEKEEEEIRASVRDKS 196
V +K+++ +E+EEI + +S
Sbjct: 2299 VQEKEEVFEEKEEIMSEEETES 2320
Score = 43.5 bits (101), Expect = 1e-04
Identities = 28/96 (29%), Positives = 56/96 (58%), Gaps = 7/96 (7%)
Query: 121 YEASDLTWEEEE--EEEGEEEEEEEEDDEDEDA-----DISLEEQSPVKQVKRLVPQKQA 173
++ +L+W+EEE +EEG+ EE+++ E+E+A + EE++ + Q + L+ Q++
Sbjct: 1723 WDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKE 1782
Query: 174 SVAKKKKLEKEEEEIRASVRDKSPVKKAKATARAKK 209
+A+ K+ EEEE R++ KK K + ++
Sbjct: 1783 KLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRER 1818
Score = 42.7 bits (99), Expect = 2e-04
Identities = 22/67 (32%), Positives = 39/67 (58%), Gaps = 10/67 (14%)
Query: 129 EEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKKLEKEEEEI 188
E++E EEEEE EE++E E+ ++ EE+ +K+ ++K++EKEEEE
Sbjct: 2238 EKQESLSSEEEEEREEEEEREEEEVREEEEE----------RKEEEEGEEKQVEKEEEEK 2287
Query: 189 RASVRDK 195
+ ++K
Sbjct: 2288 KKKKKEK 2294
Score = 41.6 bits (96), Expect = 5e-04
Identities = 25/81 (30%), Positives = 42/81 (51%), Gaps = 10/81 (12%)
Query: 118 QERYEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAK 177
+E + + +EE+EE EEE E D+E+E+ SLEE+ ++ + K
Sbjct: 2296 KEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEE----------VDREKEILK 2345
Query: 178 KKKLEKEEEEIRASVRDKSPV 198
K+K K +E+ R S+R + V
Sbjct: 2346 KEKQFKLQEQRRKSLRGRERV 2366
Score = 41.2 bits (95), Expect = 7e-04
Identities = 22/81 (27%), Positives = 45/81 (55%)
Query: 122 EASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKKL 181
E L E E++E EEEEE ++E+E + + E+ ++ + +KQ +++K
Sbjct: 2229 EMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKK 2288
Query: 182 EKEEEEIRASVRDKSPVKKAK 202
+K++E+ + V++K V + K
Sbjct: 2289 KKKKEKKKEEVQEKEEVFEEK 2309
Score = 38.1 bits (87), Expect = 0.006
Identities = 26/97 (26%), Positives = 53/97 (54%), Gaps = 7/97 (7%)
Query: 125 DLTWEEEE-EEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKKLEK 183
+L W+E+E +E EE E + E+ ++ +++ EE V++ K+L +++A +++KL +
Sbjct: 1706 NLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSE 1765
Query: 184 EE------EEIRASVRDKSPVKKAKATARAKKPGFKK 214
EE EE+ ++K K K ++ G K+
Sbjct: 1766 EETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKR 1802
Score = 38.1 bits (87), Expect = 0.006
Identities = 29/94 (30%), Positives = 48/94 (51%), Gaps = 9/94 (9%)
Query: 118 QERYEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAK 177
+ER E EEE +EE E EE++ E +E+E E++ Q K V +++ +
Sbjct: 2255 EEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMS 2314
Query: 178 KKKLE----KEEEEIRASV-----RDKSPVKKAK 202
+++ E +EEEE S+ R+K +KK K
Sbjct: 2315 EEETESLSDEEEEEESCSLEEEVDREKEILKKEK 2348
Score = 33.5 bits (75), Expect = 0.14
Identities = 25/96 (26%), Positives = 48/96 (50%), Gaps = 14/96 (14%)
Query: 118 QERYEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAK 177
Q+ + ++T EEE EGEE+E++ +++ ++E+ ++ R K+A K
Sbjct: 1536 QQYKDEEEVTLEEEVSREGEEKEQQVTEEQRH-----IQEEHKWARIHR----KRARAEK 1586
Query: 178 KK-----KLEKEEEEIRASVRDKSPVKKAKATARAK 208
K+ KL +EEE++ R + ++ A A K
Sbjct: 1587 KRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVK 1622
Score = 29.3 bits (64), Expect = 2.6
Identities = 24/94 (25%), Positives = 49/94 (52%), Gaps = 7/94 (7%)
Query: 122 EASDLTWEEEE--EEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKK 179
E L W+ E+ EEE + +EEE ++++ +E+ P ++ +RL +++ + KK
Sbjct: 1752 EEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMP-EEEERLGRKREQLIEKKM 1810
Query: 180 KLEKEEE----EIRASVRDKSPVKKAKATARAKK 209
KL ++ E + ++K + + K A+ KK
Sbjct: 1811 KLAQKRERWINSMEELTKNKMILYQKKNLAQEKK 1844
Score = 28.5 bits (62), Expect = 4.5
Identities = 24/99 (24%), Positives = 44/99 (44%), Gaps = 2/99 (2%)
Query: 118 QERYEAS--DLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASV 175
++R EA D E+ + E E EE +E E LE+Q + + +++
Sbjct: 2198 RKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEER 2257
Query: 176 AKKKKLEKEEEEIRASVRDKSPVKKAKATARAKKPGFKK 214
+++ E+EEE ++ V+K + + KK KK
Sbjct: 2258 EEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKK 2296
Score = 27.7 bits (60), Expect = 7.6
Identities = 28/90 (31%), Positives = 43/90 (47%), Gaps = 7/90 (7%)
Query: 122 EASDLTWEEEEEE--EGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKK 179
E L+ EEEEEE EEE + E++ ++ L+EQ + K L +++ +
Sbjct: 2317 ETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQ----RRKSLRGRERVLSILRG 2372
Query: 180 KLEKEEEEIRASVRDKSPVKKAKATARAKK 209
+ IR V KSP+KK +TA K
Sbjct: 2373 VPHGKGRAIRLGVL-KSPLKKLMSTALEMK 2401
>gi|55953110 retinoblastoma protein-binding zinc finger protein
isoform c [Homo sapiens]
Length = 1481
Score = 49.7 bits (117), Expect = 2e-06
Identities = 33/88 (37%), Positives = 46/88 (52%), Gaps = 1/88 (1%)
Query: 122 EASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKKL 181
E +DL EEEEEEE E+EEEEE+DD+DE D EE S + P+ + + L
Sbjct: 61 EVNDLG-EEEEEEEEEDEEEEEDDDDDELEDEGEEEASMPNENSVKEPEIRCDEKPEDLL 119
Query: 182 EKEEEEIRASVRDKSPVKKAKATARAKK 209
E+ + ++ D S V A R K+
Sbjct: 120 EEPKTTSEETLEDCSEVTPAMQIPRTKE 147
>gi|20336260 retinoblastoma protein-binding zinc finger protein
isoform b [Homo sapiens]
Length = 1682
Score = 49.7 bits (117), Expect = 2e-06
Identities = 33/88 (37%), Positives = 46/88 (52%), Gaps = 1/88 (1%)
Query: 122 EASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKKL 181
E +DL EEEEEEE E+EEEEE+DD+DE D EE S + P+ + + L
Sbjct: 262 EVNDLG-EEEEEEEEEDEEEEEDDDDDELEDEGEEEASMPNENSVKEPEIRCDEKPEDLL 320
Query: 182 EKEEEEIRASVRDKSPVKKAKATARAKK 209
E+ + ++ D S V A R K+
Sbjct: 321 EEPKTTSEETLEDCSEVTPAMQIPRTKE 348
>gi|20336258 retinoblastoma protein-binding zinc finger protein
isoform a [Homo sapiens]
Length = 1718
Score = 49.7 bits (117), Expect = 2e-06
Identities = 33/88 (37%), Positives = 46/88 (52%), Gaps = 1/88 (1%)
Query: 122 EASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKKL 181
E +DL EEEEEEE E+EEEEE+DD+DE D EE S + P+ + + L
Sbjct: 262 EVNDLG-EEEEEEEEEDEEEEEDDDDDELEDEGEEEASMPNENSVKEPEIRCDEKPEDLL 320
Query: 182 EKEEEEIRASVRDKSPVKKAKATARAKK 209
E+ + ++ D S V A R K+
Sbjct: 321 EEPKTTSEETLEDCSEVTPAMQIPRTKE 348
>gi|48255891 protein kinase C substrate 80K-H isoform 2 [Homo
sapiens]
Length = 525
Score = 49.3 bits (116), Expect = 2e-06
Identities = 27/71 (38%), Positives = 43/71 (60%), Gaps = 5/71 (7%)
Query: 129 EEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVK--RLVP---QKQASVAKKKKLEK 183
EEEEEEE EEEEE EE++E+ED+++ E+ P + ++ P Q QA + ++
Sbjct: 313 EEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKMPPYDEQTQAFIDAAQEARN 372
Query: 184 EEEEIRASVRD 194
+ EE S++D
Sbjct: 373 KFEEAERSLKD 383
Score = 28.9 bits (63), Expect = 3.4
Identities = 24/99 (24%), Positives = 46/99 (46%), Gaps = 7/99 (7%)
Query: 98 LSPPVTFQLRAGSGPVFLSGQERYEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEE 157
L+ P Q S P +E E + EEEEEE+ E + E + + A + E+
Sbjct: 297 LTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGE-----QPKPASPAEED 351
Query: 158 QSPV--KQVKRLVPQKQASVAKKKKLEKEEEEIRASVRD 194
+ P +Q + + Q + K ++ E+ +++ S+R+
Sbjct: 352 KMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRN 390
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 49.3 bits (116), Expect = 2e-06
Identities = 24/59 (40%), Positives = 39/59 (66%)
Query: 122 EASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKK 180
E+S+ EEE+EEE EEEEEEEED+E+E+ + EE+ ++ + + Q+ K+K+
Sbjct: 1067 ESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKR 1125
Score = 49.3 bits (116), Expect = 2e-06
Identities = 29/77 (37%), Positives = 44/77 (57%), Gaps = 1/77 (1%)
Query: 116 SGQERYEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASV 175
S +E E + EEEEEEE +EEEEEEE++E+E+ +I K + +K+ V
Sbjct: 1069 SEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFV 1128
Query: 176 AKKKKLEKEEEEIRASV 192
KKK+ ++ I +SV
Sbjct: 1129 LKKKR-GRKRRRINSSV 1144
Score = 47.4 bits (111), Expect = 9e-06
Identities = 32/74 (43%), Positives = 44/74 (59%), Gaps = 3/74 (4%)
Query: 110 SGPVFLSGQERYEASDLTWEEEEEEEG-EEEEEEEEDDEDEDADISLEEQSPVKQVKRLV 168
S PV + E S + EEEEEEE EEEEEEEE++EDE+ + EE+ + ++
Sbjct: 1051 SRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSP 1110
Query: 169 PQ--KQASVAKKKK 180
P+ K SVA K+K
Sbjct: 1111 PRLTKPQSVAIKRK 1124
Score = 45.1 bits (105), Expect = 5e-05
Identities = 26/64 (40%), Positives = 39/64 (60%), Gaps = 5/64 (7%)
Query: 129 EEEEEEEGEEEEEEEEDDEDEDADISLEE-----QSPVKQVKRLVPQKQASVAKKKKLEK 183
EEEEEEE EEEEEEEE+ E+E+ ++E+ +S K+ + +K+ S E+
Sbjct: 1352 EEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEE 1411
Query: 184 EEEE 187
EEE+
Sbjct: 1412 EEED 1415
Score = 33.5 bits (75), Expect = 0.14
Identities = 16/45 (35%), Positives = 25/45 (55%)
Query: 119 ERYEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQ 163
E+ +++ L EEEEEE EE E+ D D++ D +E K+
Sbjct: 1398 EKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKE 1442
Score = 31.6 bits (70), Expect = 0.53
Identities = 21/81 (25%), Positives = 37/81 (45%), Gaps = 19/81 (23%)
Query: 132 EEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKKLEKEEEEIRAS 191
E + EEEEEE+DE+E+ + EE+ ++++ E+EEEE +
Sbjct: 1063 ELSKESSEEEEEEEDEEEEEEEEEEEED-----------------EEEEEEEEEEEEEEN 1105
Query: 192 VRDKSP--VKKAKATARAKKP 210
++ P K + K+P
Sbjct: 1106 IQSSPPRLTKPQSVAIKRKRP 1126
Score = 30.8 bits (68), Expect = 0.90
Identities = 22/79 (27%), Positives = 42/79 (53%), Gaps = 4/79 (5%)
Query: 118 QERYEASDLTWEEEE---EEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQAS 174
QE+ E T +E+ ++ EEEEE+EE +ED D E+ S ++ + + ++
Sbjct: 1388 QEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAE-VEKEELPR 1446
Query: 175 VAKKKKLEKEEEEIRASVR 193
+ K+ LE +E + +V+
Sbjct: 1447 ESFKEVLENQETFLDLNVQ 1465
>gi|8923771 ELG protein isoform b [Homo sapiens]
Length = 340
Score = 48.5 bits (114), Expect = 4e-06
Identities = 31/83 (37%), Positives = 43/83 (51%), Gaps = 5/83 (6%)
Query: 130 EEEEEEGEEEEEEEEDDEDEDADISL-----EEQSPVKQVKRLVPQKQASVAKKKKLEKE 184
EEEEEE EEEEEEEE+D+D DAD + EE +KQ + +++S + E +
Sbjct: 64 EEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDEMD 123
Query: 185 EEEIRASVRDKSPVKKAKATARA 207
+ + SP K K T A
Sbjct: 124 YDLELKMISTPSPKKSMKMTMYA 146
>gi|166295179 ELG protein isoform a [Homo sapiens]
Length = 620
Score = 48.5 bits (114), Expect = 4e-06
Identities = 31/83 (37%), Positives = 43/83 (51%), Gaps = 5/83 (6%)
Query: 130 EEEEEEGEEEEEEEEDDEDEDADISL-----EEQSPVKQVKRLVPQKQASVAKKKKLEKE 184
EEEEEE EEEEEEEE+D+D DAD + EE +KQ + +++S + E +
Sbjct: 344 EEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDEMD 403
Query: 185 EEEIRASVRDKSPVKKAKATARA 207
+ + SP K K T A
Sbjct: 404 YDLELKMISTPSPKKSMKMTMYA 426
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 47.4 bits (111), Expect = 9e-06
Identities = 23/43 (53%), Positives = 30/43 (69%)
Query: 118 QERYEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSP 160
+E E D EEEEEEE EEEEEEEE++E+E+ + EE +P
Sbjct: 267 EEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAP 309
Score = 46.6 bits (109), Expect = 2e-05
Identities = 23/55 (41%), Positives = 35/55 (63%)
Query: 115 LSGQERYEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVP 169
LS +E E + EEEEE+E EEEEEEEE++E+E+ + EE+ ++ + P
Sbjct: 255 LSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAP 309
Score = 45.1 bits (105), Expect = 5e-05
Identities = 23/63 (36%), Positives = 37/63 (58%)
Query: 118 QERYEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAK 177
+E E + E+EEEEE EEEEEEEE++E+E+ + EE+ + ++ Q+ S
Sbjct: 262 EEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTS 321
Query: 178 KKK 180
+K
Sbjct: 322 AQK 324
Score = 45.1 bits (105), Expect = 5e-05
Identities = 26/68 (38%), Positives = 35/68 (51%)
Query: 118 QERYEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAK 177
+E E + EEEEEEE EEEEEEEE++E+E+ + EE+ V S K
Sbjct: 265 EEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQK 324
Query: 178 KKKLEKEE 185
+L E
Sbjct: 325 APELRGPE 332
Score = 44.7 bits (104), Expect = 6e-05
Identities = 25/76 (32%), Positives = 44/76 (57%), Gaps = 11/76 (14%)
Query: 116 SGQERYEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASV 175
+ +E + + EEE+EE EEEEEEEE+DE+E+ + EE+ +++
Sbjct: 244 ASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEE-----------EEEEEE 292
Query: 176 AKKKKLEKEEEEIRAS 191
++++ E+EEEE A+
Sbjct: 293 EEEEEEEEEEEEEEAA 308
Score = 41.6 bits (96), Expect = 5e-04
Identities = 23/64 (35%), Positives = 38/64 (59%), Gaps = 12/64 (18%)
Query: 129 EEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKKLEKEEEEI 188
E+EEEEE EEEEEE+E++E+E+ + EE +++ ++++ E+EEEE
Sbjct: 260 EDEEEEEEEEEEEEDEEEEEEEEEEEEEE------------EEEEEEEEEEEEEEEEEEA 307
Query: 189 RASV 192
V
Sbjct: 308 APDV 311
Score = 33.1 bits (74), Expect = 0.18
Identities = 25/117 (21%), Positives = 52/117 (44%), Gaps = 15/117 (12%)
Query: 109 GSGPVFLSGQERYEASDLTWEEEEE------EEGEEEEE---------EEEDDEDEDADI 153
G +F+ ++ E ++T E ++ E+ EE EEED+E+E+ +
Sbjct: 210 GEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEE 269
Query: 154 SLEEQSPVKQVKRLVPQKQASVAKKKKLEKEEEEIRASVRDKSPVKKAKATARAKKP 210
EE ++ + +++ ++++ E+EEEE + D + T+ K P
Sbjct: 270 EEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAP 326
Score = 30.4 bits (67), Expect = 1.2
Identities = 20/86 (23%), Positives = 46/86 (53%), Gaps = 4/86 (4%)
Query: 118 QERYEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAK 177
+E E + EEEEEEE EEE + +++ + S ++ ++ + P+ + SV
Sbjct: 285 EEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIV 344
Query: 178 KKKLEKEEEE----IRASVRDKSPVK 199
+ + + +++E +++V D+S ++
Sbjct: 345 EVRSDDDKDEDTHSRKSTVTDESEMQ 370
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 47.4 bits (111), Expect = 9e-06
Identities = 39/133 (29%), Positives = 66/133 (49%), Gaps = 14/133 (10%)
Query: 67 PANQEDKKMQPVTIASLQASVLPMVSMVG-VQLSPP--VTFQLRAGSGP---------VF 114
PA +E +++ P L P + G V L PP V G GP +
Sbjct: 824 PAKEEPEEL-PAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVIN 882
Query: 115 LSGQERYEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQAS 174
++ + E + EEEEEEE EEEE+ EE++EDE+ + EE+ ++ + +++
Sbjct: 883 INSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEE-EYFEEEEEEEEEFEEEFEEEEGE 941
Query: 175 VAKKKKLEKEEEE 187
+ ++++ E EEEE
Sbjct: 942 LEEEEEEEDEEEE 954
Score = 40.4 bits (93), Expect = 0.001
Identities = 22/71 (30%), Positives = 44/71 (61%), Gaps = 2/71 (2%)
Query: 118 QERYEASDLTWEEEEEEEGEEEEEEEED--DEDEDADISLEEQSPVKQVKRLVPQKQASV 175
+E E + EEEEEE+ EEEEE+EE+ +E+E+ + EE+ ++ + +++
Sbjct: 892 EEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDE 951
Query: 176 AKKKKLEKEEE 186
++++LE+ E+
Sbjct: 952 EEEEELEEVED 962
Score = 34.7 bits (78), Expect = 0.062
Identities = 17/36 (47%), Positives = 24/36 (66%)
Query: 114 FLSGQERYEASDLTWEEEEEEEGEEEEEEEEDDEDE 149
F +E E + +EEEE E EEEEEE+E++E+E
Sbjct: 921 FEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEE 956
Score = 33.9 bits (76), Expect = 0.11
Identities = 21/48 (43%), Positives = 29/48 (60%), Gaps = 7/48 (14%)
Query: 118 QERYEASDLTWEEEEEEEGEEEEEEEEDDEDEDADI-----SLEEQSP 160
+E +E + EEEEEE E+EEEEEE +E ED + +EE +P
Sbjct: 932 EEEFEEEEGELEEEEEE--EDEEEEEELEEVEDLEFGTAGGEVEEGAP 977
>gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]
Length = 185
Score = 46.2 bits (108), Expect = 2e-05
Identities = 29/79 (36%), Positives = 43/79 (54%), Gaps = 3/79 (3%)
Query: 115 LSGQERYEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQAS 174
L +E L EEEE EE EEE EEEE +E+++ D EE+ ++ K +++
Sbjct: 105 LVAEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEED---EEEEEKEEEKEEDEEEEEK 161
Query: 175 VAKKKKLEKEEEEIRASVR 193
KK + EK EEEI ++
Sbjct: 162 EGKKMEEEKVEEEIDTEIQ 180
Score = 38.1 bits (87), Expect = 0.006
Identities = 16/44 (36%), Positives = 30/44 (68%)
Query: 129 EEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQ 172
EE+EEEE +EEE+EE+++E+E +EE+ +++ + + Q
Sbjct: 140 EEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEIQRTQ 183
Score = 36.6 bits (83), Expect = 0.016
Identities = 24/66 (36%), Positives = 34/66 (51%), Gaps = 19/66 (28%)
Query: 130 EEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKKLEKEEEEIR 189
EEEEEE EEEE+EEE +EDE+ + EE K++ E+EE+E +
Sbjct: 124 EEEEEEVEEEEKEEEKEEDEEEEEKEEE-------------------KEEDEEEEEKEGK 164
Query: 190 ASVRDK 195
+K
Sbjct: 165 KMEEEK 170
Score = 34.7 bits (78), Expect = 0.062
Identities = 17/49 (34%), Positives = 30/49 (61%)
Query: 118 QERYEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKR 166
+E+ E + EEEE+EE +EE+EEEE+ E + + E+ +++R
Sbjct: 133 EEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEIQR 181
Score = 32.7 bits (73), Expect = 0.24
Identities = 16/50 (32%), Positives = 30/50 (60%)
Query: 118 QERYEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRL 167
+E E + E+EEE+E +EEEEE+E + E+ + E + +++ + L
Sbjct: 136 EEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEIQRTQYL 185
>gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo
sapiens]
Length = 528
Score = 46.2 bits (108), Expect = 2e-05
Identities = 28/64 (43%), Positives = 40/64 (62%), Gaps = 9/64 (14%)
Query: 129 EEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKKLEKEEEEI 188
EEEEEEE EEEEE EE++E+ED+ EE P L P + AS A++ K+ +E+
Sbjct: 313 EEEEEEEEEEEEEAEEEEEEEDS----EEAPP-----PLSPPQPASPAEEDKMPPYDEQT 363
Query: 189 RASV 192
+A +
Sbjct: 364 QAFI 367
Score = 27.3 bits (59), Expect = 10.0
Identities = 24/99 (24%), Positives = 44/99 (44%), Gaps = 4/99 (4%)
Query: 98 LSPPVTFQLRAGSGPVFLSGQERYEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEE 157
L+ P Q S P +E E + EEEEEE+ EE + A + E+
Sbjct: 297 LTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPL--SPPQPASPAEED 354
Query: 158 QSPV--KQVKRLVPQKQASVAKKKKLEKEEEEIRASVRD 194
+ P +Q + + Q + K ++ E+ +++ S+R+
Sbjct: 355 KMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRN 393
>gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]
Length = 587
Score = 46.2 bits (108), Expect = 2e-05
Identities = 22/53 (41%), Positives = 34/53 (64%)
Query: 129 EEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKKL 181
+EEEEEEGEEEEEE E++E+ED + EE+ ++ + Q + S +K+
Sbjct: 362 DEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSATPSRKI 414
Score = 41.2 bits (95), Expect = 7e-04
Identities = 23/52 (44%), Positives = 30/52 (57%)
Query: 118 QERYEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVP 169
+E E + EEEEEE+ EEEEEEEE++E+E E+S K L P
Sbjct: 366 EEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSATPSRKILDP 417
Score = 39.7 bits (91), Expect = 0.002
Identities = 22/46 (47%), Positives = 29/46 (63%), Gaps = 4/46 (8%)
Query: 115 LSGQERYEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSP 160
LS E E + EEEEE E EEEE+EEE++E+E+ EE+ P
Sbjct: 357 LSDDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEE----EEEEP 398
Score = 38.5 bits (88), Expect = 0.004
Identities = 21/54 (38%), Positives = 34/54 (62%), Gaps = 2/54 (3%)
Query: 124 SDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAK 177
+ L+ +E+EEEE E EEEEEE +E+E+ D EE+ ++ + PQ++ K
Sbjct: 355 ASLSDDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEE--PQQRGQGEK 406
Score = 37.0 bits (84), Expect = 0.013
Identities = 17/31 (54%), Positives = 23/31 (74%)
Query: 117 GQERYEASDLTWEEEEEEEGEEEEEEEEDDE 147
G+E E ++ EE+EEEE EEEEEEEE+ +
Sbjct: 369 GEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQ 399
Score = 28.1 bits (61), Expect = 5.8
Identities = 15/51 (29%), Positives = 29/51 (56%), Gaps = 13/51 (25%)
Query: 137 EEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKKLEKEEEE 187
+E+EEEEE+ E+E+ + EE+ ++ ++++ E+EEEE
Sbjct: 360 DEDEEEEEEGEEEEEEAEEEEEEDEEE-------------EEEEEEEEEEE 397
>gi|56711320 hypothetical protein LOC145407 [Homo sapiens]
Length = 774
Score = 45.8 bits (107), Expect = 3e-05
Identities = 25/43 (58%), Positives = 32/43 (74%), Gaps = 4/43 (9%)
Query: 115 LSGQERYEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEE 157
L +E E D EE+EE+E EEEE+EEED+ED+DAD SL+E
Sbjct: 607 LESEEGQEDED---EEDEEDEDEEEEDEEEDEEDKDAD-SLDE 645
Score = 33.5 bits (75), Expect = 0.14
Identities = 34/140 (24%), Positives = 56/140 (40%), Gaps = 35/140 (25%)
Query: 53 EKAKEEMHRVEILPPANQEDKKMQPV------TIASLQASVLPMVS-------------- 92
E+ KE+ V +P Q ++ +P+ T+ L V P V
Sbjct: 495 EEEKEDPSPVSDVPGVTQLSRRWEPLATTISTTVVPLSFEVTPTVEEQMDTVTGPNEEFT 554
Query: 93 -MVGVQLSPPVTFQLRAGSGPVF----LSGQERYEASDLT---------WEEEEEEEGEE 138
++G ++PP P S + R +T ++ E EEG+E
Sbjct: 555 PVLGSPVTPPGIMVGEPSISPALPALEASSERRTVVPSITRVNTAASYGLDQLESEEGQE 614
Query: 139 EEEEEEDDEDEDADISLEEQ 158
+ E+EED+EDED + EE+
Sbjct: 615 D-EDEEDEEDEDEEEEDEEE 633
Score = 33.5 bits (75), Expect = 0.14
Identities = 13/29 (44%), Positives = 23/29 (79%)
Query: 130 EEEEEEGEEEEEEEEDDEDEDADISLEEQ 158
EE +E+ +EE+EE+ED+E+ED + E++
Sbjct: 610 EEGQEDEDEEDEEDEDEEEEDEEEDEEDK 638
Score = 33.1 bits (74), Expect = 0.18
Identities = 20/43 (46%), Positives = 26/43 (60%), Gaps = 5/43 (11%)
Query: 117 GQERYEASDLTWEEEEEEEGEEEEEEEED----DEDEDADISL 155
GQE + D +E+EEEE EEE+EE++D DE D D L
Sbjct: 612 GQEDEDEEDEE-DEDEEEEDEEEDEEDKDADSLDEGLDGDTEL 653
Score = 32.0 bits (71), Expect = 0.40
Identities = 12/29 (41%), Positives = 22/29 (75%)
Query: 130 EEEEEEGEEEEEEEEDDEDEDADISLEEQ 158
E EE + +E+EE+EED+++E+ D +E+
Sbjct: 608 ESEEGQEDEDEEDEEDEDEEEEDEEEDEE 636
>gi|118600967 shroom family member 4 [Homo sapiens]
Length = 1493
Score = 45.4 bits (106), Expect = 4e-05
Identities = 21/48 (43%), Positives = 33/48 (68%)
Query: 113 VFLSGQERYEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSP 160
+F + Q++ + ++EEEEE EEEEEEEE++E+E+A+ EE P
Sbjct: 1114 LFRAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEELPP 1161
Score = 40.0 bits (92), Expect = 0.001
Identities = 19/30 (63%), Positives = 23/30 (76%)
Query: 129 EEEEEEEGEEEEEEEEDDEDEDADISLEEQ 158
EEEEEEE EEEEEEEE++E E+ + L Q
Sbjct: 1133 EEEEEEEEEEEEEEEEEEEAEEEEEELPPQ 1162
Score = 35.0 bits (79), Expect = 0.048
Identities = 12/42 (28%), Positives = 31/42 (73%)
Query: 129 EEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQ 170
+++++++ +++EEEEE++E+E+ + EE+ ++ + L PQ
Sbjct: 1121 QKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEELPPQ 1162
Score = 34.7 bits (78), Expect = 0.062
Identities = 14/70 (20%), Positives = 38/70 (54%)
Query: 119 ERYEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKK 178
E+Y +++++++ ++++EEEE++E+E+ + EE+ ++ + +P + S
Sbjct: 1110 EKYRLFRAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEELPPQYFSSETS 1169
Query: 179 KKLEKEEEEI 188
EE+
Sbjct: 1170 GSCALNPEEV 1179
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.124 0.336
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,084,900
Number of Sequences: 37866
Number of extensions: 502195
Number of successful extensions: 31775
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1094
Number of HSP's successfully gapped in prelim test: 447
Number of HSP's that attempted gapping in prelim test: 7182
Number of HSP's gapped (non-prelim): 10652
length of query: 214
length of database: 18,247,518
effective HSP length: 98
effective length of query: 116
effective length of database: 14,536,650
effective search space: 1686251400
effective search space used: 1686251400
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.