BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|33356547 minichromosome maintenance complex component 2 [Homo sapiens] (904 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|33356547 minichromosome maintenance complex component 2 [Homo... 1793 0.0 gi|33469919 minichromosome maintenance complex component 4 [Homo... 342 7e-94 gi|33469917 minichromosome maintenance complex component 4 [Homo... 342 7e-94 gi|23510448 minichromosome maintenance complex component 5 [Homo... 323 4e-88 gi|7427519 minichromosome maintenance complex component 6 [Homo ... 322 1e-87 gi|33469968 minichromosome maintenance complex component 7 isofo... 317 2e-86 gi|6631095 minichromosome maintenance complex component 3 [Homo ... 316 5e-86 gi|19923727 minichromosome maintenance complex component 8 isofo... 307 3e-83 gi|33469922 minichromosome maintenance complex component 7 isofo... 303 6e-82 gi|33469924 minichromosome maintenance complex component 8 isofo... 301 1e-81 gi|23397546 minichromosome maintenance complex component 9 [Homo... 145 2e-34 gi|4505101 microtubule-associated protein 7 [Homo sapiens] 45 4e-04 gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 43 0.001 gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex... 43 0.002 gi|90819233 myeloid/lymphoid or mixed-lineage leukemia (trithora... 40 0.008 gi|17975763 myelin transcription factor 1 [Homo sapiens] 40 0.008 gi|16262452 cingulin [Homo sapiens] 40 0.013 gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 39 0.017 gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 39 0.017 gi|148746195 trichohyalin [Homo sapiens] 39 0.022 gi|197333879 genetic suppressor element 1 isoform 2 [Homo sapiens] 39 0.022 gi|44955926 genetic suppressor element 1 isoform 1 [Homo sapiens] 39 0.022 gi|13540523 nucleosomal binding protein 1 [Homo sapiens] 39 0.029 gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 39 0.029 gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 39 0.029 gi|149999615 variable charge, X-linked 3B [Homo sapiens] 39 0.029 gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 38 0.037 gi|17136078 VGF nerve growth factor inducible precursor [Homo sa... 38 0.037 gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 38 0.037 gi|6005757 chromatin-specific transcription elongation factor la... 38 0.049 >gi|33356547 minichromosome maintenance complex component 2 [Homo sapiens] Length = 904 Score = 1793 bits (4643), Expect = 0.0 Identities = 904/904 (100%), Positives = 904/904 (100%) Query: 1 MAESSESFTMASSPAQRRRGNDPLTSSPGRSSRRTDALTSSPGRDLPPFEDESEGLLGTE 60 MAESSESFTMASSPAQRRRGNDPLTSSPGRSSRRTDALTSSPGRDLPPFEDESEGLLGTE Sbjct: 1 MAESSESFTMASSPAQRRRGNDPLTSSPGRSSRRTDALTSSPGRDLPPFEDESEGLLGTE 60 Query: 61 GPLEEEEDGEELIGDGMERDYRAIPELDAYEAEGLALDDEDVEELTASQREAAERAMRQR 120 GPLEEEEDGEELIGDGMERDYRAIPELDAYEAEGLALDDEDVEELTASQREAAERAMRQR Sbjct: 61 GPLEEEEDGEELIGDGMERDYRAIPELDAYEAEGLALDDEDVEELTASQREAAERAMRQR 120 Query: 121 DREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEEMIESIENLEDLKGH 180 DREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEEMIESIENLEDLKGH Sbjct: 121 DREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEEMIESIENLEDLKGH 180 Query: 181 SVREWVSMAGPRLEIHHRFKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAR 240 SVREWVSMAGPRLEIHHRFKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAR Sbjct: 181 SVREWVSMAGPRLEIHHRFKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAR 240 Query: 241 EHVLAYFLPEAPAELLQIFDEAALEVVLAMYPKYDRITNHIHVRISHLPLVEELRSLRQL 300 EHVLAYFLPEAPAELLQIFDEAALEVVLAMYPKYDRITNHIHVRISHLPLVEELRSLRQL Sbjct: 241 EHVLAYFLPEAPAELLQIFDEAALEVVLAMYPKYDRITNHIHVRISHLPLVEELRSLRQL 300 Query: 301 HLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKCNFVLGPFCQSQNQEVKPGSCPECQSAGP 360 HLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKCNFVLGPFCQSQNQEVKPGSCPECQSAGP Sbjct: 301 HLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKCNFVLGPFCQSQNQEVKPGSCPECQSAGP 360 Query: 361 FEVNMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHN 420 FEVNMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHN Sbjct: 361 FEVNMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHN 420 Query: 421 NYDGSLNTANGFPVFATVILANHVAKKDNKVAVGELTDEDVKMITSLSKDQQIGEKIFAS 480 NYDGSLNTANGFPVFATVILANHVAKKDNKVAVGELTDEDVKMITSLSKDQQIGEKIFAS Sbjct: 421 NYDGSLNTANGFPVFATVILANHVAKKDNKVAVGELTDEDVKMITSLSKDQQIGEKIFAS 480 Query: 481 IAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVS 540 IAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVS Sbjct: 481 IAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVS 540 Query: 541 SRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSI 600 SRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSI Sbjct: 541 SRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSI 600 Query: 601 HEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDIL 660 HEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDIL Sbjct: 601 HEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDIL 660 Query: 661 CVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEEEGLANGSAAEPAMPNTYGVEPLPQEVL 720 CVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEEEGLANGSAAEPAMPNTYGVEPLPQEVL Sbjct: 661 CVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEEEGLANGSAAEPAMPNTYGVEPLPQEVL 720 Query: 721 KKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGSIPITVRHIESMIRMAEAHARI 780 KKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGSIPITVRHIESMIRMAEAHARI Sbjct: 721 KKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGSIPITVRHIESMIRMAEAHARI 780 Query: 781 HLRDYVIEDDVNMAIRVMLESFIDTQKFSVMRSMRKTFARYLSFRRDNNELLLFILKQLV 840 HLRDYVIEDDVNMAIRVMLESFIDTQKFSVMRSMRKTFARYLSFRRDNNELLLFILKQLV Sbjct: 781 HLRDYVIEDDVNMAIRVMLESFIDTQKFSVMRSMRKTFARYLSFRRDNNELLLFILKQLV 840 Query: 841 AEQVTYQRNRFGAQQDTIEVPEKDLVDKARQINIHNLSAFYDSELFRMNKFSHDLKRKMI 900 AEQVTYQRNRFGAQQDTIEVPEKDLVDKARQINIHNLSAFYDSELFRMNKFSHDLKRKMI Sbjct: 841 AEQVTYQRNRFGAQQDTIEVPEKDLVDKARQINIHNLSAFYDSELFRMNKFSHDLKRKMI 900 Query: 901 LQQF 904 LQQF Sbjct: 901 LQQF 904 >gi|33469919 minichromosome maintenance complex component 4 [Homo sapiens] Length = 863 Score = 342 bits (878), Expect = 7e-94 Identities = 256/826 (30%), Positives = 399/826 (48%), Gaps = 104/826 (12%) Query: 2 AESSESFTMASSPAQRRRGNDPLTSSPGRSSRRTDALTSSPGRDLPPFEDESEGLLGTEG 61 A++ S SSP+QRRRG D S+ + +SPG DL + Sbjct: 21 AQTPRSEDARSSPSQRRRGED------STSTGELQPMPTSPGVDL-------------QS 61 Query: 62 PLEEEEDGEELIGDGMERDYRAIPELDAYEAEGLALDDEDVEELTASQREAAERAMRQRD 121 P ++ L + AIP LD + L + +RQR Sbjct: 62 PAAQDV----LFSSPPQMHSSAIP-LDFDVSSPLTYGTPSSRVEGTPRSGVRGTPVRQRP 116 Query: 122 REAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEEMIESIENLEDLKGHS 181 LG ++GL D DG E+++ S ++L G Sbjct: 117 -----DLGSAQKGLQVDLQS------------------DGAAAEDIVASEQSL----GQK 149 Query: 182 VREW---VSMAGPRLEIHHRFKNFLRTHVD---SHGHNV--------FKERISDMCKENR 227 + W V++A + F+ FL+ +D NV + +R+ ++ Sbjct: 150 LVIWGTDVNVAACK----ENFQRFLQRFIDPLAKEEENVGIDITEPLYMQRLGEINVIGE 205 Query: 228 ESLVVNYEDLAAREHVLAYFLPEAPAELLQIFDEAALEVVLAMYPKYDRITNH-IHVRIS 286 L VN E + + + L L P E++ FD A E+ YP D I H I VR Sbjct: 206 PFLNVNCEHIKSFDKNLYRQLISYPQEVIPTFDMAVNEIFFDRYP--DSILEHQIQVRPF 263 Query: 287 HLPLVEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKCNFVLGPFCQSQNQE 346 + + +R+L ++QLI SG+V + ++P++ + C C + + Sbjct: 264 NALKTKNMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVCAHTTRVE-MDRGRI 322 Query: 347 VKPGSCPECQSAGPFEVNMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSC 406 +P C C + + +++ + Q I++QESP + AG+ P + DLVD Sbjct: 323 AEPSVCGRCHTTHSMALIHNRSLFSDKQMIKLQESPEDMPAGQTPHTVILFAHNDLVDKV 382 Query: 407 KPGDEIELTGIYHN-NYDGSLNTANGFPVFATVILANHVAKKDNKVAVGE--------LT 457 +PGD + +TGIY + +N V+ T I H K D K G + Sbjct: 383 QPGDRVNVTGIYRAVPIRVNPRVSNVKSVYKTHIDVIHYRKTDAKRLHGLDEEAEQKLFS 442 Query: 458 DEDVKMITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPG--GKHKVRG 515 ++ V+++ LS+ I E++ +++APSIY HEDIK+G+ L LFGG K+ G+ K R Sbjct: 443 EKRVELLKELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFGGTRKDFSHTGRGKFRA 502 Query: 516 DINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGA 575 +IN+LLCGDPGT+KSQ L+Y+ + R +T+G+G+SAVGLTAYV + P +R+ L+ GA Sbjct: 503 EINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKDPETRQLVLQTGA 562 Query: 576 LVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGG 635 LVL+D G+C IDEFDKMN+ R+ +HE MEQQ++SI+KAGI+ L AR +V+AAANPI Sbjct: 563 LVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPIES 622 Query: 636 RYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEEEG 695 +++P T EN+ L ++SRFD++ ++ D D D LA +V + + +E Sbjct: 623 QWNPKKTTIENIQLPHTLLSRFDLIFLLLDPQDEAYDRRLAHHLVALYYQSEEQAEE--- 679 Query: 696 LANGSAAEPAMPNTYGVEPLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESM 755 E L VLK YI YA + P+L++ + + Y D+RK Sbjct: 680 -----------------ELLDMAVLKDYIAYAHSTIMPRLSEEASQALIEAYVDMRKIGS 722 Query: 756 ATGSIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLES 801 + G + R +ES+IR+AEAHA++ L + V DV A R+ E+ Sbjct: 723 SRGMVSAYPRQLESLIRLAEAHAKVRLSNKVEAIDVEEAKRLHREA 768 >gi|33469917 minichromosome maintenance complex component 4 [Homo sapiens] Length = 863 Score = 342 bits (878), Expect = 7e-94 Identities = 256/826 (30%), Positives = 399/826 (48%), Gaps = 104/826 (12%) Query: 2 AESSESFTMASSPAQRRRGNDPLTSSPGRSSRRTDALTSSPGRDLPPFEDESEGLLGTEG 61 A++ S SSP+QRRRG D S+ + +SPG DL + Sbjct: 21 AQTPRSEDARSSPSQRRRGED------STSTGELQPMPTSPGVDL-------------QS 61 Query: 62 PLEEEEDGEELIGDGMERDYRAIPELDAYEAEGLALDDEDVEELTASQREAAERAMRQRD 121 P ++ L + AIP LD + L + +RQR Sbjct: 62 PAAQDV----LFSSPPQMHSSAIP-LDFDVSSPLTYGTPSSRVEGTPRSGVRGTPVRQRP 116 Query: 122 REAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEEMIESIENLEDLKGHS 181 LG ++GL D DG E+++ S ++L G Sbjct: 117 -----DLGSAQKGLQVDLQS------------------DGAAAEDIVASEQSL----GQK 149 Query: 182 VREW---VSMAGPRLEIHHRFKNFLRTHVD---SHGHNV--------FKERISDMCKENR 227 + W V++A + F+ FL+ +D NV + +R+ ++ Sbjct: 150 LVIWGTDVNVAACK----ENFQRFLQRFIDPLAKEEENVGIDITEPLYMQRLGEINVIGE 205 Query: 228 ESLVVNYEDLAAREHVLAYFLPEAPAELLQIFDEAALEVVLAMYPKYDRITNH-IHVRIS 286 L VN E + + + L L P E++ FD A E+ YP D I H I VR Sbjct: 206 PFLNVNCEHIKSFDKNLYRQLISYPQEVIPTFDMAVNEIFFDRYP--DSILEHQIQVRPF 263 Query: 287 HLPLVEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKCNFVLGPFCQSQNQE 346 + + +R+L ++QLI SG+V + ++P++ + C C + + Sbjct: 264 NALKTKNMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVCAHTTRVE-MDRGRI 322 Query: 347 VKPGSCPECQSAGPFEVNMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSC 406 +P C C + + +++ + Q I++QESP + AG+ P + DLVD Sbjct: 323 AEPSVCGRCHTTHSMALIHNRSLFSDKQMIKLQESPEDMPAGQTPHTVILFAHNDLVDKV 382 Query: 407 KPGDEIELTGIYHN-NYDGSLNTANGFPVFATVILANHVAKKDNKVAVGE--------LT 457 +PGD + +TGIY + +N V+ T I H K D K G + Sbjct: 383 QPGDRVNVTGIYRAVPIRVNPRVSNVKSVYKTHIDVIHYRKTDAKRLHGLDEEAEQKLFS 442 Query: 458 DEDVKMITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPG--GKHKVRG 515 ++ V+++ LS+ I E++ +++APSIY HEDIK+G+ L LFGG K+ G+ K R Sbjct: 443 EKRVELLKELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFGGTRKDFSHTGRGKFRA 502 Query: 516 DINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGA 575 +IN+LLCGDPGT+KSQ L+Y+ + R +T+G+G+SAVGLTAYV + P +R+ L+ GA Sbjct: 503 EINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKDPETRQLVLQTGA 562 Query: 576 LVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGG 635 LVL+D G+C IDEFDKMN+ R+ +HE MEQQ++SI+KAGI+ L AR +V+AAANPI Sbjct: 563 LVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPIES 622 Query: 636 RYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEEEG 695 +++P T EN+ L ++SRFD++ ++ D D D LA +V + + +E Sbjct: 623 QWNPKKTTIENIQLPHTLLSRFDLIFLLLDPQDEAYDRRLAHHLVALYYQSEEQAEE--- 679 Query: 696 LANGSAAEPAMPNTYGVEPLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESM 755 E L VLK YI YA + P+L++ + + Y D+RK Sbjct: 680 -----------------ELLDMAVLKDYIAYAHSTIMPRLSEEASQALIEAYVDMRKIGS 722 Query: 756 ATGSIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLES 801 + G + R +ES+IR+AEAHA++ L + V DV A R+ E+ Sbjct: 723 SRGMVSAYPRQLESLIRLAEAHAKVRLSNKVEAIDVEEAKRLHREA 768 >gi|23510448 minichromosome maintenance complex component 5 [Homo sapiens] Length = 734 Score = 323 bits (828), Expect = 4e-88 Identities = 235/741 (31%), Positives = 373/741 (50%), Gaps = 74/741 (9%) Query: 194 EIHHRFKNFLRTHVDSHGHNVFKERISDMCKENRES----LVVNYEDLAAREHVLAYFLP 249 ++ RFK FLR + F + D K + + V EDLA+ + LA +L Sbjct: 30 QLQRRFKEFLRQYRVGTDRTGFTFKYRDELKRHYNLGEYWIEVEMEDLASFDEDLADYLY 89 Query: 250 EAPAELLQIFDEAALEV---VLAMYPKYDRITNHIHVRISHLPLVEELRSLRQLHLNQLI 306 + PAE LQ+ +EAA EV V P + + I V + +RSL+ ++ L+ Sbjct: 90 KQPAEHLQLLEEAAKEVADEVTRPRPSGEEVLQDIQVMLKSDASPSSIRSLKSDMMSHLV 149 Query: 307 RTSGVVTSCTGVLPQLSMVKYNCNKCNFVLGPFCQSQNQE--VKPGSC-------PECQS 357 + G++ + + V + + + C C L E P C P+C Sbjct: 150 KIPGIIIAASAVRAKATRISIQCRSCRNTLTNIAMRPGLEGYALPRKCNTDQAGRPKCP- 208 Query: 358 AGPFEVNMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGI 417 P+ + ++ ++Q +++QE P V G +PR L D PG+ + + GI Sbjct: 209 LDPYFIMPDKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYCDRYLCDKVVPGNRVTIMGI 268 Query: 418 YHNNYDGSLNTANGFPVFATVILANHV--------AKKDNKVAVGELTDEDVKMITSLSK 469 Y G L T+ G I ++++ + G ++ ++ + L+ Sbjct: 269 YSIKKFG-LTTSRGRDRVGVGIRSSYIRVLGIQVDTDGSGRSFAGAVSPQEEEEFRRLAA 327 Query: 470 DQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKN-PGGKHKVRGDINVLLCGDPGTA 528 + E I SIAPSI+G D+K+ +A LFGG K P G + RGDIN+L+ GDPGTA Sbjct: 328 LPNVYEVISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPDGLTR-RGDINLLMLGDPGTA 386 Query: 529 KSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDE 588 KSQ LK++EK S ++T+G+G+SA GLTA V R P SR + +E GA+VLAD GV IDE Sbjct: 387 KSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVMRDPSSRNFIMEGGAMVLADGGVVCIDE 446 Query: 589 FDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVD 648 FDKM + DR +IHEAMEQQ+ISI+KAGI T+L +RC+V+AAAN + GR+D + +N+D Sbjct: 447 FDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDET-KGEDNID 505 Query: 649 LTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEEEGLANGSAAEPAMPN 708 I+SRFD++ +V+D + +D MLA+ V+ HV A+ Sbjct: 506 FMPTILSRFDMIFIVKDEHNEERDVMLAKHVITLHV-------------------SALTQ 546 Query: 709 TYGVE-PLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLR-------KESMATGSI 760 T VE + LKK+I Y + + P+L+ +K+ Y +R ++S SI Sbjct: 547 TQAVEGEIDLAKLKKFIAYCRVKCGPRLSAEAAEKLKNRYIIMRSGARQHERDSDRRSSI 606 Query: 761 PITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESFIDTQKFSVMRSMRKTFAR 820 PITVR +E+++R+AEA +++ L+ + E DV A+R+ S +D ++ T + Sbjct: 607 PITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLFQVSTLDA-------ALSGTLSG 659 Query: 821 YLSF-RRDNNELLLFILKQLVAEQVTYQRNRFGAQQDTIEVPEKDLVDKARQINIHNLSA 879 F +++ E+L I KQL +R G+Q + + K + IH + Sbjct: 660 VEGFTSQEDQEMLSRIEKQL------KRRFAIGSQVSEHSIIKDFTKQKYPEHAIHKVLQ 713 Query: 880 FYDSELFRMNKFSHDLKRKMI 900 + R + H ++RK++ Sbjct: 714 L----MLRRGEIQHRMQRKVL 730 >gi|7427519 minichromosome maintenance complex component 6 [Homo sapiens] Length = 821 Score = 322 bits (824), Expect = 1e-87 Identities = 212/660 (32%), Positives = 343/660 (51%), Gaps = 87/660 (13%) Query: 199 FKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEA------- 251 F +FL S G + + ++ + R +LVV++ DL L+ + E Sbjct: 30 FLDFLEEFQSSDGEIKYLQLAEELIRPERNTLVVSFVDLEQFNQQLSTTIQEEFYRVYPY 89 Query: 252 PAELLQIFDEAALEVVLAMYPKYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGV 311 L+ F + E+ LA +V LP ++R L + L R SG Sbjct: 90 LCRALKTFVKDRKEIPLA---------KDFYVAFQDLPTRHKIRELTSSRIGLLTRISGQ 140 Query: 312 VTSCTGVLPQLSMVKYNCNKCNFVLGPFCQSQNQEVKPGSC--PECQSAGPFEVNMEETI 369 V V P+L + C C V+ + Q + +P C P C + F ++ ++ Sbjct: 141 VVRTHPVHPELVSGTFLCLDCQTVIRDV-EQQFKYTQPNICRNPVCANRRRFLLDTNKSR 199 Query: 370 YQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIY----------- 418 + ++Q++RIQE+ ++ G +PRS + IL A+ V+S + GD+ + TG Sbjct: 200 FVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVESAQAGDKCDFTGTLIVVPDVSKLST 259 Query: 419 ---HNNYDGSLNTANGFPV---------------FATVILANHVAKKDNKVAVGELTDED 460 + ++ +G+ + V LA VA + + EL DE+ Sbjct: 260 PGARAETNSRVSGVDGYETEGIRGLRALGVRDLSYRLVFLACCVAPTNPRFGGKELRDEE 319 Query: 461 V--------------KMITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKN 506 + + +S+D+ + + S+ P+I+G++++KRG+ L LFGG PK Sbjct: 320 QTAESIKNQMTVKEWEKVFEMSQDKNLYHNLCTSLFPTIHGNDEVKRGVLLMLFGGVPKT 379 Query: 507 PGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVS 566 G +RGDINV + GDP TAKSQFLK++E+ S RA++T+G+ +SA GLTA V R S Sbjct: 380 TGEGTSLRGDINVCIVGDPSTAKSQFLKHVEEFSPRAVYTSGKASSAAGLTAAVVRDEES 439 Query: 567 REWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTV 626 E+ +EAGAL+LAD GVC IDEFDKM+ +D+ +IHEAMEQQ+ISI+KAG+ +L AR ++ Sbjct: 440 HEFVIEAGALMLADNGVCCIDEFDKMDVRDQVAIHEAMEQQTISITKAGVKATLNARTSI 499 Query: 627 IAAANPIGGRYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRH 686 +AAANPI G YD S + +N++L+ PI+SRFD+ ++ D + V D +AR +V H Sbjct: 500 LAAANPISGHYDRSKSLKQNINLSAPIMSRFDLFFILVDECNEVTDYAIARRIVDLH--- 556 Query: 687 HPSNKEEEGLANGSAAEPAMPNTYGVEPLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKM 746 S E ++ Y ++ +++Y+++A++ PK+++ +D + + Sbjct: 557 -------------SRIEESIDRVYSLDD-----IRRYLLFARQ-FKPKISKESEDFIVEQ 597 Query: 747 YSDLRK---ESMATGSIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESFI 803 Y LR+ + S ITVR +ESMIR++EA AR+H D V V A R++ +S I Sbjct: 598 YKHLRQRDGSGVTKSSWRITVRQLESMIRLSEAMARMHCCDEVQPKHVKEAFRLLNKSII 657 >gi|33469968 minichromosome maintenance complex component 7 isoform 1 [Homo sapiens] Length = 719 Score = 317 bits (813), Expect = 2e-86 Identities = 193/518 (37%), Positives = 299/518 (57%), Gaps = 42/518 (8%) Query: 294 LRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKCNFVLGPFCQSQNQEVKPG-SC 352 +R +R + +L+ G+VT + V P++ + Y C++C + Q+ P C Sbjct: 149 IREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCDQCG--AETYQPIQSPTFMPLIMC 206 Query: 353 P--ECQ---SAGPFEVNMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCK 407 P ECQ S G + + + +Q +++QE +V G +PRS ++ + + Sbjct: 207 PSQECQTNRSGGRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQ 266 Query: 408 PGDEIELTGIYHNNYDGSLNTANGFPVFATVILANHVAK----KDNKVAVGELTDEDVKM 463 PGD + +TGI+ + T + A+ + K +D++ GELT E+++ Sbjct: 267 PGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEAHRIVKMNKSEDDESGAGELTREELRQ 326 Query: 464 ITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCG 523 I ++ EK+ ASIAP IYGHED+K+ L L L GG ++P G K+RG+IN+ L G Sbjct: 327 IA----EEDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQSPRGM-KIRGNINICLMG 381 Query: 524 DPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGV 583 DPG AKSQ L YI++++ R+ +TTG+G+S VGLTA V R VS E TLE GALVLAD+GV Sbjct: 382 DPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGV 441 Query: 584 CLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTF 643 C IDEFDKM + DRT+IHE MEQQ+ISI+KAGI+T+L ARC+++AAANP GRY+P + Sbjct: 442 CCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSL 501 Query: 644 SENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFV--VGSHVRHHPSNKEEEGLANGSA 701 +N+ L ++SRFD+L +++D D D LA+ + V H R PS Sbjct: 502 EQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPSQ----------- 550 Query: 702 AEPAMPNTYGVEPLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGSIP 761 EPL +++++YI +E+ P + + D + Y ++R+E+ A+ Sbjct: 551 ----------FEPLDMKLMRRYIAMCREK-QPMVPESLADYITAAYVEMRREAWASKDAT 599 Query: 762 IT-VRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVM 798 T R + +++R++ A AR+ + D V ++DVN AIR+M Sbjct: 600 YTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLM 637 >gi|6631095 minichromosome maintenance complex component 3 [Homo sapiens] Length = 808 Score = 316 bits (810), Expect = 5e-86 Identities = 217/644 (33%), Positives = 339/644 (52%), Gaps = 42/644 (6%) Query: 193 LEIHHRFKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAP 252 +E+ +++L D +++ ++ ++ +N+ L+VN DL + A L Sbjct: 10 VELREAQRDYLDFLDDEEDQGIYQSKVRELISDNQYRLIVNVNDLRRKNEKRANRLLNNA 69 Query: 253 AELLQIFDEAALEVVLAMYPKYDRITNHIHVRISHLPLVEEL--RSLRQLHLNQLIRTSG 310 E L F A + V ++ Y + +V + + + R+L L+ ++ G Sbjct: 70 FEELVAFQRALKDFVASIDATYAKQYEEFYVGLEGSFGSKHVSPRTLTSCFLSCVVCVEG 129 Query: 311 VVTSCTGVLPQLSMVKYNCNKCNFVLGPFCQSQNQEVK-PGSC---PECQSAGPFEVNME 366 +VT C+ V P++ + C + V P S + + P E Sbjct: 130 IVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTLVAFPSSSVYPTKDEENNPLETEYG 189 Query: 367 ETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSL 426 ++Y+++Q I IQE P K AG+LPRS D IL DLVD KPGD +++ G Y Sbjct: 190 LSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVGTYRCLPGKKG 249 Query: 427 NTANGFPVFATVILANHVAKKDNKVAVGELTDEDVKMITSLSK--DQQIGEKIFASIAPS 484 +G F TV++A +V K+ +K A + ED+ I SK + I +++ S+APS Sbjct: 250 GYTSG--TFRTVLIACNV-KQMSKDAQPSFSAEDIAKIKKFSKTRSKDIFDQLAKSLAPS 306 Query: 485 IYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAI 544 I+GH+ +K+ + L GG ++ +RGDIN+LL GDP AKSQ L+Y+ + RAI Sbjct: 307 IHGHDYVKKAILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAI 366 Query: 545 FTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAM 604 TTG+G+S VGLTA V + E LEAGA+VLADRGV IDEFDKM+D DRT+IHE M Sbjct: 367 PTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVM 426 Query: 605 EQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDILCVVR 664 EQ ++I+KAGI L ARC+V+AAANP+ GRYD T EN+ L + ++SRFD+L ++ Sbjct: 427 EQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIML 486 Query: 665 DTVDPVQDEMLARFVVGSHVRHHPSNKEEEGLANGSAAEPAM---PN------------- 708 D +DP QD ++ V+ H P ++ + + GSA + PN Sbjct: 487 DQMDPEQDREISDHVLRMHRYRAPGEQDGDAMPLGSAVDILATDDPNFSQEDQQDTQIYE 546 Query: 709 -----TYGVEPLPQEV-----LKKYIIYAKERVHPKLNQMDQDKVAKMYSDLR-KESMAT 757 +G + +++ +KKYI AK + P L Q +A+ YS LR ++SM++ Sbjct: 547 KHDNLLHGTKKKKEKMVSAAFMKKYIHVAK-IIKPVLTQESATYIAEEYSRLRSQDSMSS 605 Query: 758 GSI---PITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVM 798 + P+T R +E++IR+A AHA+ + V D A+ ++ Sbjct: 606 DTARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELV 649 >gi|19923727 minichromosome maintenance complex component 8 isoform 1 [Homo sapiens] Length = 840 Score = 307 bits (786), Expect = 3e-83 Identities = 227/757 (29%), Positives = 372/757 (49%), Gaps = 88/757 (11%) Query: 125 GRGLGRMR---------RGLLYDSDEEDEERPARKRRQVERATEDGEE-------DEEMI 168 GRG GR R G E E RP + +R +E + + M Sbjct: 7 GRGFGRGRFQSWKRGRGGGNFSGKWREREHRPDLSKTTGKRTSEQTPQFLLSTKTPQSMQ 66 Query: 169 ESIENLEDLKGHSV--REWVSMAGPRLEIHHRFKNFLRTHVDSHGHNVFKERISDMCKEN 226 +++ KG + E S + P +E F+ F H+D + K+ I E Sbjct: 67 STLDRFIPYKGWKLYFSEVYSDSSPLIEKIQAFEKFFTRHIDLYD----KDEI-----ER 117 Query: 227 RESLVVNYEDLAAREHV------LAYFLPEAPAELLQIFDEAALEVVLAMYPKY------ 274 + S++V++++L V +A L +AP + L A +V+ ++ Sbjct: 118 KGSILVDFKELTEGGEVTNLIPDIATELRDAPEKTLACMGLAIHQVLTKDLERHAAELQA 177 Query: 275 -DRITN---------HIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLSM 324 + ++N HIH R+ + + +L+++R + + I G V + + P + Sbjct: 178 QEGLSNDGETMVNVPHIHARVYNYEPLTQLKNVRANYYGKYIALRGTVVRVSNIKPLCTK 237 Query: 325 VKYNCNKCNFVLGPFCQSQNQEVKPGSCPECQSAGPFEVNMEE---TIYQNYQRIRIQE- 380 + + C C + F + P CP G + T+ ++Q I+IQE Sbjct: 238 MAFLCAACGEIQS-FPLPDGKYSLPTKCPVPVCRGRSFTALRSSPLTVTMDWQSIKIQEL 296 Query: 381 -SPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYH--NNYDGSLNTANGFPVFAT 437 S + AGR+PR+ + L+ DLVDSC PGD + +TGI N +GS N N +F Sbjct: 297 MSDDQREAGRIPRTIECELVHDLVDSCVPGDTVTITGIVKVSNAEEGSRNK-NDKCMFLL 355 Query: 438 VILANHVAKKDNKVAVG-----------ELTDEDVKMITSLSKDQQIGEKIFASIAPSIY 486 I AN ++ + E + +D+ I + ++ + + I S+ P I+ Sbjct: 356 YIEANSISNSKGQKTKSSEDGCKHGMLMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVIF 415 Query: 487 GHEDIKRGLALALFGGEPKNPGGKHKV--RGDINVLLCGDPGTAKSQFLKYIEKVSSRAI 544 GHE +K GLALALFGG K K+++ RGD ++L+ GDPG KSQ L+ V+ R + Sbjct: 416 GHELVKAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGV 475 Query: 545 FTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAM 604 + G + GLT + + S ++ LEAGALVL D+G+C IDEFDKM +Q + + EAM Sbjct: 476 YVCGNTTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQALL-EAM 534 Query: 605 EQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDILCVVR 664 EQQSIS++KAG+V SL AR ++IAAANP+GG Y+ + T SEN+ + ++SRFD++ ++ Sbjct: 535 EQQSISLAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFILL 594 Query: 665 DTVDPVQDEMLARFVVG--------------SHVRHHPSNKEEEGLANGSAAEPAMPNTY 710 DT + D +L+ V+ + + SN + + + Sbjct: 595 DTPNEHHDHLLSEHVIAIRAGKQRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVVP 654 Query: 711 G--VEPLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGSIPITVRHIE 768 G ++P+P ++L+KYI YA++ V+P+L+ + Y +LRK+S S PIT R +E Sbjct: 655 GETIDPIPHQLLRKYIGYARQYVYPRLSTEAARVLQDFYLELRKQSQRLNSSPITTRQLE 714 Query: 769 SMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESFIDT 805 S+IR+ EA AR+ LR+ ++D + +M S + T Sbjct: 715 SLIRLTEARARLELREEATKEDAEDIVEIMKYSMLGT 751 >gi|33469922 minichromosome maintenance complex component 7 isoform 2 [Homo sapiens] Length = 543 Score = 303 bits (775), Expect = 6e-82 Identities = 180/459 (39%), Positives = 272/459 (59%), Gaps = 39/459 (8%) Query: 352 CP--ECQ---SAGPFEVNMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSC 406 CP ECQ S G + + + +Q +++QE +V G +PRS ++ + Sbjct: 30 CPSQECQTNRSGGRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIA 89 Query: 407 KPGDEIELTGIYHNNYDGSLNTANGFPVFATVILANHVAK----KDNKVAVGELTDEDVK 462 +PGD + +TGI+ + T + A+ + K +D++ GELT E+++ Sbjct: 90 QPGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEAHRIVKMNKSEDDESGAGELTREELR 149 Query: 463 MITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLC 522 I ++ EK+ ASIAP IYGHED+K+ L L L GG ++P G K+RG+IN+ L Sbjct: 150 QIA----EEDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQSPRGM-KIRGNINICLM 204 Query: 523 GDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRG 582 GDPG AKSQ L YI++++ R+ +TTG+G+S VGLTA V R VS E TLE GALVLAD+G Sbjct: 205 GDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQG 264 Query: 583 VCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLT 642 VC IDEFDKM + DRT+IHE MEQQ+ISI+KAGI+T+L ARC+++AAANP GRY+P + Sbjct: 265 VCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRS 324 Query: 643 FSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFV--VGSHVRHHPSNKEEEGLANGS 700 +N+ L ++SRFD+L +++D D D LA+ + V H R PS Sbjct: 325 LEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPSQ---------- 374 Query: 701 AAEPAMPNTYGVEPLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGSI 760 EPL +++++YI +E+ P + + D + Y ++R+E+ A+ Sbjct: 375 -----------FEPLDMKLMRRYIAMCREK-QPMVPESLADYITAAYVEMRREAWASKDA 422 Query: 761 PIT-VRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVM 798 T R + +++R++ A AR+ + D V ++DVN AIR+M Sbjct: 423 TYTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLM 461 >gi|33469924 minichromosome maintenance complex component 8 isoform 2 [Homo sapiens] Length = 824 Score = 301 bits (772), Expect = 1e-81 Identities = 222/751 (29%), Positives = 367/751 (48%), Gaps = 92/751 (12%) Query: 125 GRGLGRMR---------RGLLYDSDEEDEERPARKRRQVERATEDGEE-------DEEMI 168 GRG GR R G E E RP + +R +E + + M Sbjct: 7 GRGFGRGRFQSWKRGRGGGNFSGKWREREHRPDLSKTTGKRTSEQTPQFLLSTKTPQSMQ 66 Query: 169 ESIENLEDLKGHSV--REWVSMAGPRLEIHHRFKNFLRTHVDSHGHNVFKERISDMCKEN 226 +++ KG + E S + P +E F+ F H+D + K+ I E Sbjct: 67 STLDRFIPYKGWKLYFSEVYSDSSPLIEKIQAFEKFFTRHIDLYD----KDEI-----ER 117 Query: 227 RESLVVNYEDLAAREHV------LAYFLPEAPAELLQIFDEAALEVVLAMYPKY------ 274 + S++V++++L V +A L +AP + L A +V+ ++ Sbjct: 118 KGSILVDFKELTEGGEVTNLIPDIATELRDAPEKTLACMGLAIHQVLTKDLERHAAELQA 177 Query: 275 -DRITN---------HIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLSM 324 + ++N HIH R+ + + +L+++R + + I G V + + P + Sbjct: 178 QEGLSNDGETMVNVPHIHARVYNYEPLTQLKNVRANYYGKYIALRGTVVRVSNIKPLCTK 237 Query: 325 VKYNCNKCNFVLGPFCQSQNQEVKPGSCPECQSAGPFEVNMEE---TIYQNYQRIRIQE- 380 + + C C + F + P CP G + T+ ++Q I+IQE Sbjct: 238 MAFLCAACGEIQS-FPLPDGKYSLPTKCPVPVCRGRSFTALRSSPLTVTMDWQSIKIQEL 296 Query: 381 -SPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSLNTANGFPVFATVI 439 S + AGR+PR+ + L+ DLVDSC PGD + +TGI + N+ Sbjct: 297 MSDDQREAGRIPRTIECELVHDLVDSCVPGDTVTITGIVKVSNAEEANS----------- 345 Query: 440 LANHVAKKDNKVAVG-------ELTDEDVKMITSLSKDQQIGEKIFASIAPSIYGHEDIK 492 ++N +K G E + +D+ I + ++ + + I S+ P I+GHE +K Sbjct: 346 ISNSKGQKTKSSEDGCKHGMLMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVIFGHELVK 405 Query: 493 RGLALALFGGEPKNPGGKHKV--RGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQG 550 GLALALFGG K K+++ RGD ++L+ GDPG KSQ L+ V+ R ++ G Sbjct: 406 AGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGNT 465 Query: 551 ASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSIS 610 + GLT + + S ++ LEAGALVL D+G+C IDEFDKM +Q + + EAMEQQSIS Sbjct: 466 TTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQALL-EAMEQQSIS 524 Query: 611 ISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPV 670 ++KAG+V SL AR ++IAAANP+GG Y+ + T SEN+ + ++SRFD++ ++ DT + Sbjct: 525 LAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFILLDTPNEH 584 Query: 671 QDEMLARFVVG--------------SHVRHHPSNKEEEGLANGSAAEPAMPNTYG--VEP 714 D +L+ V+ + + SN + + + G ++P Sbjct: 585 HDHLLSEHVIAIRAGKQRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVVPGETIDP 644 Query: 715 LPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGSIPITVRHIESMIRMA 774 +P ++L+KYI YA++ V+P+L+ + Y +LRK+S S PIT R +ES+IR+ Sbjct: 645 IPHQLLRKYIGYARQYVYPRLSTEAARVLQDFYLELRKQSQRLNSSPITTRQLESLIRLT 704 Query: 775 EAHARIHLRDYVIEDDVNMAIRVMLESFIDT 805 EA AR+ LR+ ++D + +M S + T Sbjct: 705 EARARLELREEATKEDAEDIVEIMKYSMLGT 735 >gi|23397546 minichromosome maintenance complex component 9 [Homo sapiens] Length = 391 Score = 145 bits (366), Expect = 2e-34 Identities = 113/369 (30%), Positives = 183/369 (49%), Gaps = 37/369 (10%) Query: 214 VFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAELLQIFDEA----ALEVVLA 269 + KER D +VVN L + + P+E+L IFD A AL ++ + Sbjct: 28 ILKERDEDA----HYPVVVNAMTLFETNMEIGEYFNMFPSEVLTIFDSALRRSALTILQS 83 Query: 270 M-YPKYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVK-- 326 + P+ + ++H RIS LP+ EL +R+ H+ + + G S TG + + S+VK Sbjct: 84 LSQPEAVSMKQNLHARISGLPVCPEL--VRE-HIPKT-KDVGHFLSVTGTVIRTSLVKVL 139 Query: 327 -----YNCNKCN--FVLGPFCQSQNQEVKPGSCPECQSAGPFE------VNMEETIYQNY 373 Y CNKC FV+ + +P SCP +S + ++ T ++Y Sbjct: 140 EFERDYMCNKCKHVFVIKADFEQYYTFCRPSSCPSLESCDSSKFTCLSGLSSSPTRCRDY 199 Query: 374 QRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSLNTANGFP 433 Q I+IQE +++ G +PRS IL DLVDSCK GD++ + GI + Sbjct: 200 QEIKIQEQVQRLSVGSIPRSMKVILEDDLVDSCKSGDDLTIYGIVMQRWKPFQQDVR--- 256 Query: 434 VFATVILANHVAKKDNKVAVGELTDEDVKMITS-----LSKDQQIGEK-IFASIAPSIYG 487 ++L + + +N+ + G + DE+V+ D G I AS+ P ++G Sbjct: 257 CEVEIVLKANYIQVNNEQSSGIIMDEEVQKEFEDFWEYYKSDPFAGRNVILASLCPQVFG 316 Query: 488 HEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTT 547 +K +A+ L GG + +VRG+ ++LL GDPGT KSQFLKY K++ R++ TT Sbjct: 317 MYLVKLAVAMVLAGGIQRTDATGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTT 376 Query: 548 GQGASAVGL 556 G G+++ G+ Sbjct: 377 GIGSTSAGI 385 >gi|4505101 microtubule-associated protein 7 [Homo sapiens] Length = 749 Score = 44.7 bits (104), Expect = 4e-04 Identities = 47/175 (26%), Positives = 76/175 (43%), Gaps = 23/175 (13%) Query: 11 ASSPAQRRRGNDPLTSSPGRSSRRTDALTSSPGRDLPPFEDESEGLLGTEGPLEEEEDGE 70 AS+PA + S+P + + ++ +S G P +E+ LL + L E+ + Sbjct: 440 ASAPAPAPVPTPAMVSAPSSTVNASASVKTSAGTTDP---EEATRLLAEKRRLAREQREK 496 Query: 71 ELIGDGMERDYRAIPELDAYEAEGLALDDEDVEELTASQREAAERAMRQRDREAGRGLGR 130 E ER+ R EL+ + E LA EE T + E + R ++ RE L R Sbjct: 497 E------ERERREQEELERQKREELA--QRVAEERTTRREEESRRLEAEQAREKEEQLQR 548 Query: 131 MRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEEMIESIENL-EDLKGHSVRE 184 + EER R+R + ERA EE+ + E E + ++ + H RE Sbjct: 549 -----------QAEERALREREEAERAQRQKEEEARVREEAERVRQEREKHFQRE 592 >gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo sapiens] Length = 1152 Score = 43.1 bits (100), Expect = 0.001 Identities = 38/118 (32%), Positives = 48/118 (40%), Gaps = 7/118 (5%) Query: 50 EDESEGLLGTEGPLE-EEEDGEELIGDGMERDYRAIPELDAYEAEGLALDDEDVEELTAS 108 E+E EG EG E EEE+GE G G E E + E EG D E E Sbjct: 897 EEEGEGEGEEEGEGEGEEEEGE---GKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEG 953 Query: 109 QREAAERAMRQRDREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEE 166 + E E E G G G G + +EE+ E + E E+GE +EE Sbjct: 954 EWEGEEEEGEGEGEEEGEGEGEEGEG---EGEEEEGEGEGEEEEGEEEGEEEGEGEEE 1008 Score = 42.4 bits (98), Expect = 0.002 Identities = 35/117 (29%), Positives = 49/117 (41%), Gaps = 9/117 (7%) Query: 50 EDESEGLLGTEGPLEEEEDGEELIGDGMERDYRAIPELDAYEAEGLALDDEDVEELTASQ 109 E+E EG EG E E +GEE G+G E + E + E EG + + E + Sbjct: 959 EEEGEG----EGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGE 1014 Query: 110 REAAERAMRQRDREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEE 166 E + + E G G G G +EE EER + R + EE+EE Sbjct: 1015 EEEEGEVEGEVEGEEGEGEGEEEEG-----EEEGEEREKEGEGEENRRNREEEEEEE 1066 Score = 42.0 bits (97), Expect = 0.003 Identities = 37/122 (30%), Positives = 52/122 (42%), Gaps = 13/122 (10%) Query: 50 EDESEGLLGTEGPLEE-----EEDGEELIGDGMERDYRAIPELDAYEAEGLALDDEDVEE 104 E+E EG EG EE EE+GEE G+G E + E + + EG ++E E Sbjct: 905 EEEGEG----EGEEEEGEGKGEEEGEEGEGEGEEEE----GEGEGEDGEGEGEEEEGEWE 956 Query: 105 LTASQREAAERAMRQRDREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEED 164 + E + + E G G G G +EE EE + E +GEE+ Sbjct: 957 GEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEE 1016 Query: 165 EE 166 EE Sbjct: 1017 EE 1018 Score = 40.4 bits (93), Expect = 0.008 Identities = 38/121 (31%), Positives = 52/121 (42%), Gaps = 17/121 (14%) Query: 50 EDESEGLLGTEGPLEEEEDGEELIGDGMERDYRAIPELDAYEAEGLALDDEDVEELTASQ 109 E+E EG EG EEE +GEE G+G E + E + E EG +E+ EE + Sbjct: 828 EEEEEG----EGE-EEEGEGEEEEGEGEEEEGEGKGEEEGEEGEG----EEEGEE---GE 875 Query: 110 REAAERAMRQRDREAGRGLGRMRRGLLYDSDE-----EDEERPARKRRQVERATEDGEED 164 E E E G G G G +E E+EE + + E +GEE+ Sbjct: 876 GEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEE 935 Query: 165 E 165 E Sbjct: 936 E 936 Score = 38.1 bits (87), Expect = 0.037 Identities = 38/123 (30%), Positives = 52/123 (42%), Gaps = 6/123 (4%) Query: 50 EDESEGLLGTEGPLEEEE---DGEEL-IGDGMERDYRAIPELDAYEAEGLALDDEDVEEL 105 E E EG EG EEEE +GEE G+G E + E + E EG ++E E Sbjct: 882 EGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEG 941 Query: 106 TASQREAAERAMR-QRDREAGRGLGRMR-RGLLYDSDEEDEERPARKRRQVERATEDGEE 163 + E E + + E G G G G + + E EE + E E+GEE Sbjct: 942 EDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEE 1001 Query: 164 DEE 166 + E Sbjct: 1002 EGE 1004 Score = 35.0 bits (79), Expect = 0.32 Identities = 53/198 (26%), Positives = 75/198 (37%), Gaps = 34/198 (17%) Query: 22 DPLTSSPGRSSRRTDALTSSPGRDLPPFEDESEGLLGTEGPLEEEEDGEELIGDG-MERD 80 D S G++ +A GR E+ S G + EE E GE+ G G MER Sbjct: 632 DKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQD--EEREKGEKDKGRGEMERP 689 Query: 81 YRAIPELDAYEAEGLALDDEDVEELTASQREAAERAMRQRDREAG----RGLGRMRRGLL 136 EL AE D EE +RE + R ++ E G G G G Sbjct: 690 GEGEKEL----AEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEG-- 743 Query: 137 YDSDEEDE------------------ERPARKRRQVERA--TEDGEEDEEMIESIENLED 176 D +EE+E E+ +R++ ERA E GEE+ + E E + Sbjct: 744 -DREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETE 802 Query: 177 LKGHSVREWVSMAGPRLE 194 +G E + G +E Sbjct: 803 GRGEEKEEGGEVEGGEVE 820 Score = 35.0 bits (79), Expect = 0.32 Identities = 33/114 (28%), Positives = 52/114 (45%), Gaps = 21/114 (18%) Query: 51 DESEGLLGTEGPLEEEEDGEELIGDGMERDYRAIP-ELDAYEAEGLALDDEDVEELTASQ 109 +E EG E E EE+GE G+G E + + E++ E EG ++E EE + Sbjct: 991 EEEEGEEEGEEEGEGEEEGE---GEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEERE 1047 Query: 110 REAAERAMRQRDREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEE 163 +E E +R+RE +EE+EE ++ + E +DGEE Sbjct: 1048 KE-GEGEENRRNRE----------------EEEEEEGKYQETGEEENERQDGEE 1084 Score = 34.7 bits (78), Expect = 0.41 Identities = 42/137 (30%), Positives = 55/137 (40%), Gaps = 19/137 (13%) Query: 50 EDESEGLLGTEGPLEEEE---DGEELIGDGMERDYRAIPELDAYEAEGLALDDEDVEELT 106 E E EG G EG EEEE +GEE G+G E + E + E EG + E E Sbjct: 936 EGEGEGEDG-EGEGEEEEGEWEGEEEEGEG-EGEEEGEGEGEEGEGEGEEEEGEGEGEEE 993 Query: 107 ASQREAAERAMRQRDREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEE 166 + E E E G G G EE+EE + E +GEE+E Sbjct: 994 EGEEEGEEEG---EGEEEGEGEG-----------EEEEEGEVEGEVEGEEGEGEGEEEEG 1039 Query: 167 MIESIENLEDLKGHSVR 183 E E ++ +G R Sbjct: 1040 EEEGEEREKEGEGEENR 1056 Score = 30.8 bits (68), Expect = 5.9 Identities = 29/120 (24%), Positives = 48/120 (40%), Gaps = 1/120 (0%) Query: 66 EEDGEELIGDGMERDYRAIPELDAYEAEGLALDDEDVEELTASQREAAERAMRQRDREAG 125 EE+G++ G+ E + R + + E EG +++ E + E + + E G Sbjct: 788 EEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEG 847 Query: 126 RGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGE-EDEEMIESIENLEDLKGHSVRE 184 G G + EE E + + E E+GE E EE E E+ +G E Sbjct: 848 EGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEE 907 >gi|4759128 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 [Homo sapiens] Length = 1099 Score = 42.7 bits (99), Expect = 0.002 Identities = 41/128 (32%), Positives = 58/128 (45%), Gaps = 8/128 (6%) Query: 50 EDESEGLLGTEGPLEEEEDGEELIGDGMERDYRAIPELDAYEAEGLALDDEDVEELTASQ 109 + E EG T+G EE ED E G G + + E+ A + E + E T SQ Sbjct: 778 QPEGEGETETQGKGEECEDENEAEGKG-DNEGEDEGEIHAEDGEMKGNEGE-----TESQ 831 Query: 110 REAAERAMRQRDREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEEMIE 169 +AE ++ E G G G DS+EE+EE ++ + E E+ EE+EE E Sbjct: 832 ELSAENHGEAKNDEKGVEDGGGSDG--GDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEE 889 Query: 170 SIENLEDL 177 N E L Sbjct: 890 EKGNEEPL 897 >gi|90819233 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 isoform 2 [Homo sapiens] Length = 1651 Score = 40.4 bits (93), Expect = 0.008 Identities = 23/66 (34%), Positives = 35/66 (53%), Gaps = 3/66 (4%) Query: 98 DDEDVEELTASQREAAERAMRQRDREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERA 157 +D+DV+ + QR AER R +R + L MR+ D ++EE R+R++ ER Sbjct: 1584 EDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEE---RRRQEEERT 1640 Query: 158 TEDGEE 163 D EE Sbjct: 1641 KRDAEE 1646 >gi|17975763 myelin transcription factor 1 [Homo sapiens] Length = 1121 Score = 40.4 bits (93), Expect = 0.008 Identities = 44/181 (24%), Positives = 71/181 (39%), Gaps = 8/181 (4%) Query: 13 SPAQRRRGNDPLTSSPGRSSRRTDALTSSPGRDLPPFEDESEGLLGTEGPLEEEEDGEEL 72 SP + G++P+ S+ S + L G + E +EE+ Sbjct: 135 SPVKSHFGSNPIGSATASSKGSYSSYQGIIATSLLNL-----GQIAEETLVEEDLGQAAK 189 Query: 73 IGDGMERDYRAIPELDAYEA--EGLALDDEDVEELTASQREAAERAMRQRDREAGRGLGR 130 G G+ + E A E +GL + ED EE+ E ++ Q +A Sbjct: 190 PGPGIVHLLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESS 249 Query: 131 MRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEEMIESIENLEDLKGHSVREWVSMAG 190 ++G+L +EEDEE + + E E+ EE+EE E E E+ + E A Sbjct: 250 KQKGIL-SHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAA 308 Query: 191 P 191 P Sbjct: 309 P 309 Score = 37.0 bits (84), Expect = 0.083 Identities = 32/141 (22%), Positives = 56/141 (39%), Gaps = 26/141 (18%) Query: 58 GTEGPLEEEEDGEELIGDGMERDYRAIPEL-------DAYEAEGLALDDEDVEELTASQR 110 G +G + ED EE++ ER P+ ++ + +G+ +E+ EE Sbjct: 210 GEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEE------ 263 Query: 111 EAAERAMRQRDREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEEMIES 170 E E + D E + +EE+EE + + E E+ EE+EE Sbjct: 264 EEEEEEEEEEDEEE-------------EEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPD 310 Query: 171 IENLEDLKGHSVREWVSMAGP 191 + ED S ++ + GP Sbjct: 311 VIFQEDTSHTSAQKAPELRGP 331 >gi|16262452 cingulin [Homo sapiens] Length = 1203 Score = 39.7 bits (91), Expect = 0.013 Identities = 46/155 (29%), Positives = 69/155 (44%), Gaps = 33/155 (21%) Query: 56 LLGTEGPLEEEEDGEELIGDGMERDYRAIPELDAYEAEGLALDDEDVEELTASQRE---- 111 +LG E L+E L+ G + R +L EAE L+ E L ASQ E Sbjct: 739 ILGLEQQLKETRG---LVDGGEAVEARLRDKLQRLEAEKQQLE----EALNASQEEEGSL 791 Query: 112 -AAERAMRQRDREAGRGLGRM----------------RRGLLYDSDEEDEERPARKRRQV 154 AA+RA+ R EA RGL R+ +R +L E EE+ R V Sbjct: 792 AAAKRALEARLEEAQRGLARLGQEQQTLNRALEEEGKQREVLRRGKAELEEQKRLLDRTV 851 Query: 155 ERATED----GEEDEEMIESIE-NLEDLKGHSVRE 184 +R ++ GE+ ++ ++ ++ LED K + RE Sbjct: 852 DRLNKELEKIGEDSKQALQQLQAQLEDYKEKARRE 886 Score = 31.6 bits (70), Expect = 3.5 Identities = 41/173 (23%), Positives = 73/173 (42%), Gaps = 27/173 (15%) Query: 56 LLGTEGPLEEEEDGEELIGDGMERDYRAIPELDAYEAEGLALDDE-----------DVEE 104 LL T LEE +G++ + + + R + L E +A D+ D E+ Sbjct: 469 LLETRELLEEVLEGKQRVEEQLRLRERELTALKGALKEEVASRDQEVEHVRQQYQRDTEQ 528 Query: 105 LTASQREAA-ERAMRQRDREAGRGLGRMRRGLLYDSDEE-----------DEERPARKRR 152 L S ++A + A+ + +R+ L R + L ++ EE E+ A K+ Sbjct: 529 LRRSMQDATQDHAVLEAERQKMSALVRGLQRELEETSEETGHWQSMFQKNKEDLRATKQE 588 Query: 153 QVERATEDGEEDEEMIESIENLEDLKGHSVREWVSMAGPRLEIHHRFKNFLRT 205 ++ E E +EE+ E IE L+ + + + AG ++ K LRT Sbjct: 589 LLQLRMEKEEMEEELGEKIEVLQ----RELEQARASAGDTRQVEVLKKELLRT 637 >gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo sapiens] Length = 1130 Score = 39.3 bits (90), Expect = 0.017 Identities = 44/169 (26%), Positives = 64/169 (37%), Gaps = 24/169 (14%) Query: 11 ASSPAQRRRGNDPLTSSPGRSSRRTDALTSSPGR-DLPPFEDESEGLLGTEGPLEEEEDG 69 AS P + + L ++PG PG LPP + EG G GP EED Sbjct: 819 ASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPALEED- 877 Query: 70 EELIGDGMERDYRAIPELDAYEAEGLALDDEDVEELTASQREAAERAMRQRDREAGRGLG 129 +I + E + E E ++ED EE + E E Sbjct: 878 LTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEE-------------- 923 Query: 130 RMRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEEMIESIENLEDLK 178 + +EE+E + + E E+ EEDEE E +E +EDL+ Sbjct: 924 --------EEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLE 964 >gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] Length = 953 Score = 39.3 bits (90), Expect = 0.017 Identities = 40/121 (33%), Positives = 55/121 (45%), Gaps = 9/121 (7%) Query: 59 TEGPLEEEEDG--EELIGDGMERDYRAIPELDAYEAEGLALDDEDVEE-LTASQREAAER 115 T P EEE D E+ D + ELD +E L D+E EE A Q + AE+ Sbjct: 93 TSSPCEEEGDEGEEDRTSDLRDEASSVTRELDEHE---LDYDEEVPEEPAPAVQEDEAEK 149 Query: 116 AMRQRDREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEEMIESIENLE 175 A + D E G G R S E E A K ++ E +DGE D+ I+ ++LE Sbjct: 150 AGAEDDEEKGEGTPREEGKAGVQSVGEKESLEAAKEKKKE--DDDGEIDDGEIDD-DDLE 206 Query: 176 D 176 + Sbjct: 207 E 207 Score = 32.0 bits (71), Expect = 2.7 Identities = 27/113 (23%), Positives = 47/113 (41%), Gaps = 11/113 (9%) Query: 64 EEEEDGEELIGDGMERDYRAIPELDAYEAEGLALDDEDVEELTASQRE------AAERAM 117 E+EE + L D + RD + +LD L+DE+ SQ E +RA Sbjct: 15 EDEEQPQGLSDDDILRDSGSDQDLDGAGVRASDLEDEESAARGPSQEEEDNHSDEEDRAS 74 Query: 118 RQRDREAGRGLGRMRRG-----LLYDSDEEDEERPARKRRQVERATEDGEEDE 165 + ++ + + RG + DE +E+R + R + T + +E E Sbjct: 75 EPKSQDQDSEVNELSRGPTSSPCEEEGDEGEEDRTSDLRDEASSVTRELDEHE 127 Score = 32.0 bits (71), Expect = 2.7 Identities = 38/141 (26%), Positives = 50/141 (35%), Gaps = 30/141 (21%) Query: 50 EDESEGLLGTEGPLEEEEDG----EELIGDGMERDYRAI-------PELDAYEAEGLALD 98 EDE GP +EEED E+ + +D + P E EG Sbjct: 49 EDEESA---ARGPSQEEEDNHSDEEDRASEPKSQDQDSEVNELSRGPTSSPCEEEG---- 101 Query: 99 DEDVEELTASQREAAERAMRQRDREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERAT 158 DE E+ T+ R+ A R+ D D DEE E PA ++ E Sbjct: 102 DEGEEDRTSDLRDEASSVTRELDEHE------------LDYDEEVPEEPAPAVQEDEAEK 149 Query: 159 EDGEEDEEMIESIENLEDLKG 179 E+DEE E E G Sbjct: 150 AGAEDDEEKGEGTPREEGKAG 170 Score = 30.8 bits (68), Expect = 5.9 Identities = 18/53 (33%), Positives = 26/53 (49%) Query: 114 ERAMRQRDREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEE 166 E R+R+RE R R RR + + E E R+RR+ E E + DE+ Sbjct: 411 ENRQRERERERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEK 463 >gi|148746195 trichohyalin [Homo sapiens] Length = 1943 Score = 38.9 bits (89), Expect = 0.022 Identities = 43/174 (24%), Positives = 75/174 (43%), Gaps = 19/174 (10%) Query: 63 LEEEEDGEELIGDGMERDYRAIPELDAYEAEGLALDDEDVEELTASQREAAERAMRQRDR 122 L+EEE EEL + E+ R E E E L ++ E+L +RE R R+R Sbjct: 906 LQEEE--EELQREEREKRRRQEQERQYREEEQL---QQEEEQLLREEREKRRRQERERQY 960 Query: 123 EAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEEMIESIENLEDLKGHSV 182 + L + LL EE E+R ++R + R E+ +++EE + E+ + Sbjct: 961 RKDKKLQQKEEQLL---GEEPEKRRRQEREKKYREEEELQQEEEQLLR----EEREKRRR 1013 Query: 183 REWVSMAGPRLEIHHRFKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYED 236 +EW + E+ + LR + K R+ + ++ RE + E+ Sbjct: 1014 QEWERQYRKKDELQQEEEQLLREERE-------KRRLQERERQYREEEELQQEE 1060 Score = 34.3 bits (77), Expect = 0.54 Identities = 38/154 (24%), Positives = 60/154 (38%), Gaps = 21/154 (13%) Query: 44 RDLPPFEDESEGLLGTEGPLEEEEDGEELIGDGMERDYRAIPELDAYEAEGLALDDE--- 100 R+ + E E LLG E ++ +ER YR EL E + L + E Sbjct: 1051 REEEELQQEEEQLLGEERETRRRQE--------LERQYRKEEELQQEEEQLLREEPEKRR 1102 Query: 101 ------DVEELTASQREAAERAMRQRDREAGRGLGRMRRGLLYDSDEED----EERPARK 150 E Q+E + +R++ + L R R EE+ EE R+ Sbjct: 1103 RQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRR 1162 Query: 151 RRQVERATEDGEEDEEMIESIENLEDLKGHSVRE 184 R+++ER + EE ++ E + E K RE Sbjct: 1163 RQELERQYREEEELQQEEEQLLREEQEKRRQERE 1196 Score = 33.5 bits (75), Expect = 0.92 Identities = 31/109 (28%), Positives = 51/109 (46%), Gaps = 12/109 (11%) Query: 64 EEEEDGEELIGDGMERDYRAIPELDAYEAEGLALDDEDVEELTASQREAAERAMRQRDRE 123 E+EE ++L+ ER + + E L E+VE L Q E E+ +++ + E Sbjct: 570 EQEERRDQLLKREEERRQQRLKREQEERLEQ-RLKREEVERL--EQEERREQRLKREEPE 626 Query: 124 AGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATED---GEEDEEMIE 169 RR L S+E++E R + RR+ + E EE+EE +E Sbjct: 627 ------EERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLE 669 Score = 32.7 bits (73), Expect = 1.6 Identities = 27/111 (24%), Positives = 49/111 (44%), Gaps = 16/111 (14%) Query: 66 EEDGEELIGDGMERDYRAIPELDAYEAEGLALDDEDV--EELTASQREAAERAMRQRDRE 123 ++ E+L+G+ E+ R E E E L ++E + EE +R+ ER R++D Sbjct: 967 QQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDE- 1025 Query: 124 AGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEEMIESIENL 174 +EE R R++R+++ E+EE+ + E L Sbjct: 1026 -------------LQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQL 1063 Score = 31.6 bits (70), Expect = 3.5 Identities = 43/168 (25%), Positives = 71/168 (42%), Gaps = 17/168 (10%) Query: 24 LTSSPGRSSRRTDALTSSPGRDLPPFEDESEGLLGTEGPLEEEEDGE--ELIGDGMERDY 81 L PG+ R+ R+L E++SE E + D E + ER+ Sbjct: 129 LEEEPGQRRRQK---RQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREE 185 Query: 82 RAIPELDAYEAEGLALDDEDVEELTASQREAAERAMRQRDREAGRGLGRMRRGLLYDSDE 141 R E +G ++ EE +RE E +R++ RE + R R+ ++ + Sbjct: 186 RRAEEEQLQSCKGHETEEFPDEE-QLRRRELLE--LRRKGREEKQQQRRERQDRVF---Q 239 Query: 142 EDEERPARKRRQVERATEDGEEDE------EMIESIENLEDLKGHSVR 183 E+EE+ RKR V R E+ ++E E+ E E L L+ +R Sbjct: 240 EEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELR 287 Score = 31.2 bits (69), Expect = 4.6 Identities = 24/92 (26%), Positives = 38/92 (41%), Gaps = 15/92 (16%) Query: 81 YRAIPELDAYEAEGLALDDEDVEELTASQREAAERAMRQRDREAGRGLGRMRRGLLYDSD 140 Y A+ + + E A D L ++E +R RDR+ + Sbjct: 86 YYALGQATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQL---------------E 130 Query: 141 EEDEERPARKRRQVERATEDGEEDEEMIESIE 172 EE +R +KR++ ER +GEE E E +E Sbjct: 131 EEPGQRRRQKRQEQERELAEGEEQSEKQERLE 162 Score = 31.2 bits (69), Expect = 4.6 Identities = 17/59 (28%), Positives = 34/59 (57%) Query: 109 QREAAERAMRQRDREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEEM 167 QR +A +R++ R R +R + +EE++E+ R+RR+ E+ + EE+E++ Sbjct: 782 QRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQL 840 Score = 30.8 bits (68), Expect = 5.9 Identities = 25/84 (29%), Positives = 40/84 (47%), Gaps = 2/84 (2%) Query: 97 LDDEDVEELTASQREAAE-RAMRQRDREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVE 155 L ++ +L A +R+ E R + + + + R R R EE+E+ R+R Q Sbjct: 790 LREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQL 849 Query: 156 RATEDG-EEDEEMIESIENLEDLK 178 + EDG +ED+E S E D K Sbjct: 850 QEEEDGLQEDQERRRSQEQRRDQK 873 >gi|197333879 genetic suppressor element 1 isoform 2 [Homo sapiens] Length = 1113 Score = 38.9 bits (89), Expect = 0.022 Identities = 25/116 (21%), Positives = 50/116 (43%), Gaps = 9/116 (7%) Query: 78 ERDYRAIPELDAYEAEGLALDDEDVEELTASQREAAERAMRQRDREAGRGLGRMRRGLLY 137 E + ++ L + GL+ + ++E +RE R+R+ + R R R Sbjct: 205 ELSHSSLAALHSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKE 264 Query: 138 DSDEEDEERPARKRRQVERATEDGEEDEEMIES---------IENLEDLKGHSVRE 184 E++ ER + R++ER E ++E++ + + L L+GH+ E Sbjct: 265 REQEKEREREKERERELERQREQRAREKELLAAKALEPSFLPVAELHGLRGHATEE 320 >gi|44955926 genetic suppressor element 1 isoform 1 [Homo sapiens] Length = 1217 Score = 38.9 bits (89), Expect = 0.022 Identities = 25/116 (21%), Positives = 50/116 (43%), Gaps = 9/116 (7%) Query: 78 ERDYRAIPELDAYEAEGLALDDEDVEELTASQREAAERAMRQRDREAGRGLGRMRRGLLY 137 E + ++ L + GL+ + ++E +RE R+R+ + R R R Sbjct: 309 ELSHSSLAALHSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKE 368 Query: 138 DSDEEDEERPARKRRQVERATEDGEEDEEMIES---------IENLEDLKGHSVRE 184 E++ ER + R++ER E ++E++ + + L L+GH+ E Sbjct: 369 REQEKEREREKERERELERQREQRAREKELLAAKALEPSFLPVAELHGLRGHATEE 424 >gi|13540523 nucleosomal binding protein 1 [Homo sapiens] Length = 282 Score = 38.5 bits (88), Expect = 0.029 Identities = 39/184 (21%), Positives = 74/184 (40%), Gaps = 34/184 (18%) Query: 14 PAQRRRGNDPLTSSPGRSSRRTDALTSSPGRDLPPFEDESEGLLGTEGPLEEE------- 66 P ++ G + P R S R A+ ++ P S + T+ + EE Sbjct: 2 PKRKAAGQGDMRQEPKRRSARLSAMLVPVTPEVKPKRTSSSRKMKTKSDMMEENIDTSAQ 61 Query: 67 ---EDGEELIGDGMERDYRA--------IPELDAYEAEGLALDDEDVEELT---ASQREA 112 E +E + +E DY I E A E E + + +E++E+ T ++EA Sbjct: 62 AVAETKQEAV---VEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEA 118 Query: 113 AERAMRQRDREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEEMIESIE 172 ++ + + + D+ +E+ A K + E+ EDG+ED+ E E Sbjct: 119 VAAEVKNEEEDQKED----------EEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGE 168 Query: 173 NLED 176 + ++ Sbjct: 169 DAKE 172 Score = 37.4 bits (85), Expect = 0.064 Identities = 35/130 (26%), Positives = 61/130 (46%), Gaps = 4/130 (3%) Query: 50 EDESEGLLGTEGPLEE-EEDGEELIGDGMERDYRAIPELDAYEAEGLALDDEDVEELTAS 108 ++E +G G E E+ EEDG+E +G E+ A + D + E + ED +E Sbjct: 137 QNEEKGEAGKEDKDEKGEEDGKE-DKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGED 195 Query: 109 QREAAERAMRQ--RDREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEE 166 ++E +R ++ E G+ G + G E+++ER K + E G+E E+ Sbjct: 196 EKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKED 255 Query: 167 MIESIENLED 176 + E E E+ Sbjct: 256 LKEEEEGKEE 265 >gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] Length = 290 Score = 38.5 bits (88), Expect = 0.029 Identities = 30/106 (28%), Positives = 44/106 (41%), Gaps = 3/106 (2%) Query: 63 LEEEEDGEELIGDGMERDYRAIPELDA---YEAEGLALDDEDVEELTASQREAAERAMRQ 119 +E + + E+ G ERD E D E E D D + T ++RE +Q Sbjct: 121 IERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQ 180 Query: 120 RDREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEEDE 165 ++RE R R R + D ER +++ Q ER E E E Sbjct: 181 KERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGE 226 Score = 33.9 bits (76), Expect = 0.70 Identities = 24/77 (31%), Positives = 35/77 (45%), Gaps = 18/77 (23%) Query: 109 QREAAERAMRQRDREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEEMI 168 +RE R RQRDR+ G+ E D ER ++ R+ ER E +E +E Sbjct: 226 ERETDRRRERQRDRDRGK--------------ERDRERDRKEERKKERKKERKKERKEKK 271 Query: 169 ESIENLEDLKGHSVREW 185 + + ED K R+W Sbjct: 272 KEEKRREDKK----RKW 284 Score = 31.2 bits (69), Expect = 4.6 Identities = 32/125 (25%), Positives = 53/125 (42%), Gaps = 13/125 (10%) Query: 51 DESEGLLGTE------GPLEEEEDGEELIGDGMERDYRAIPELDAYEAEGLALDDED--- 101 D S G LG++ G + +D + GD +R+ + E E + D + Sbjct: 48 DFSRGRLGSQESPRSWGLGQAHKDAD---GDDRQRERDRVREKTEKERDRDRKRDRERRR 104 Query: 102 VEELTASQREAAERAMRQRDREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDG 161 E+ T R+ ++ +RDRE + GR R E D +R + RQ E+ DG Sbjct: 105 KEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEK-DRDG 163 Query: 162 EEDEE 166 + + E Sbjct: 164 QRETE 168 >gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] Length = 2400 Score = 38.5 bits (88), Expect = 0.029 Identities = 45/182 (24%), Positives = 72/182 (39%), Gaps = 16/182 (8%) Query: 20 GNDPLTSSPGRSSRRTDALTSSPGRDLPPFEDESEGLLGTEGPLEEEEDGEELIGDGMER 79 G + S G ++ + T D P D G E P E EE+ +E G+ E Sbjct: 2022 GVEAQPKSEGEEAQEVEGETQKTEGDAQPESD------GVEAP-EAEEEAQEAEGEVQEA 2074 Query: 80 DYRAIPE---LDAYEAEGLALDDEDVEELTASQREAAERAMRQRDREAGRGLGRMRRGLL 136 + A PE +DA EAEG A + + E ++ EA + + G + Sbjct: 2075 EGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEG--I 2132 Query: 137 YDSDEEDEERPARKRRQVERATEDGEEDEEMIESIENLE----DLKGHSVREWVSMAGPR 192 + E E +P + + + A + + + E IE+ E E +L+G E A P Sbjct: 2133 EAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPE 2192 Query: 193 LE 194 E Sbjct: 2193 SE 2194 >gi|149999615 variable charge, X-linked 3B [Homo sapiens] Length = 216 Score = 38.5 bits (88), Expect = 0.029 Identities = 41/152 (26%), Positives = 59/152 (38%), Gaps = 10/152 (6%) Query: 26 SSPGRSSRRTDALTSSPGRDLPPFEDESEGLLGTEGPLEEEEDGEELIGDGMERDYRAIP 85 ++PG S + + L P +LPP E SEG PL +E + EE + E + Sbjct: 72 AAPGPSDQPSQEL---PQHELPPEEPVSEGT--QHDPLSQESELEEPLSQESEVEEPLSQ 126 Query: 86 ELDAYEAEGLALDDEDVEELTASQREAAERAMRQRDREAGRGLGRMRRGLLYDSDEEDEE 145 E E L E E SQ E + Q + E L + + S E + E Sbjct: 127 ESQVEEP----LSQESEVEEPLSQESQVEEPLSQ-ESEVEEPLSQESQVEEPLSQESEME 181 Query: 146 RPARKRRQVERATEDGEEDEEMIESIENLEDL 177 P + QVE E EE + +E+L Sbjct: 182 EPLSQESQVEEPLSQESEMEEPLSQESEMEEL 213 >gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapiens] Length = 1341 Score = 38.1 bits (87), Expect = 0.037 Identities = 46/169 (27%), Positives = 71/169 (42%), Gaps = 33/169 (19%) Query: 12 SSPAQRRRGNDPLTSSPGRSSR-RTDALTSSPGRDLPPFEDESEGLLGTEGPLEEEEDGE 70 S PA+ + +P R+ R R D R+L E+E E EEEED E Sbjct: 243 SQPAEEEEDQE----TPSRNLRVRAD-------RNLKTEEEEEE-------EEEEEEDDE 284 Query: 71 ELIGDGMERDYRAIPELDAYEAEGLALDDEDVEELTASQREAAERAMRQRDREAGRGLGR 130 E GD + R P L ++ EG EE+ R E M +R + + Sbjct: 285 EEEGDDEGQKSREAPILKEFKEEG--------EEIP---RVKPEEMMDERPKTRSQEQEV 333 Query: 131 MRRGLLYDSDEEDEERPARKRRQVE---RATEDGEEDEEMIESIENLED 176 + RG + +E+ + R+Q E + T EE+E I+S + L++ Sbjct: 334 LERGGRFTRSQEEARKSHLARQQQEKEMKTTSPLEEEEREIKSSQGLKE 382 Score = 32.7 bits (73), Expect = 1.6 Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 1/78 (1%) Query: 103 EELTASQREAAERAMRQRDREAGRGLGRMRRGLLYDSDEEDEERPARKRR-QVERATEDG 161 EE S E + R+ R ++ G +EED+E P+R R + +R + Sbjct: 211 EEKGDSDDEKPRKGERRSSRVRQARAAKLSEGSQPAEEEEDQETPSRNLRVRADRNLKTE 270 Query: 162 EEDEEMIESIENLEDLKG 179 EE+EE E E+ E+ +G Sbjct: 271 EEEEEEEEEEEDDEEEEG 288 Score = 30.8 bits (68), Expect = 5.9 Identities = 32/124 (25%), Positives = 48/124 (38%), Gaps = 8/124 (6%) Query: 65 EEEDGEELIGDGMERDYRA-----IPELDAYEAEGLALDDEDVEELTASQREAAERAMRQ 119 +EE +L+ D + A +P D+ + A E +E ++E E ++ Sbjct: 1203 QEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREKRRKEQEEEEQKE 1262 Query: 120 RDREAGRGLGRM--RRGLLYDSDEEDEERPARKRRQVERATEDGEEDEEMIESIENLEDL 177 R++EA R R R S E D ER + R D E D E + D Sbjct: 1263 REKEAERERNRQLEREKRREHSRERDRERERERERDRGDRDRDRERDRERGRE-RDRRDT 1321 Query: 178 KGHS 181 K HS Sbjct: 1322 KRHS 1325 >gi|17136078 VGF nerve growth factor inducible precursor [Homo sapiens] Length = 615 Score = 38.1 bits (87), Expect = 0.037 Identities = 40/138 (28%), Positives = 57/138 (41%), Gaps = 30/138 (21%) Query: 43 GRDLPPFEDESEGLLGTEGPLEEEEDGEELIGDGMERDYRAIPELDAYEAEGLALDDEDV 102 GR L +E E E +E GEE +G+ E + A E +A EAE Sbjct: 348 GRGLQEAAEERESAREEEEAEQERRGGEERVGE--EDEEAAEAEAEAEEAE--------- 396 Query: 103 EELTASQREAAERAMRQRDREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGE 162 R+ A + D EAG + EE P +R++ E E GE Sbjct: 397 -----RARQNALLFAEEEDGEAGA-----------EDKRSQEETPGHRRKEAEGTEEGGE 440 Query: 163 E--DEEM-IESIENLEDL 177 E DEEM ++I++L +L Sbjct: 441 EEDDEEMDPQTIDSLIEL 458 >gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] Length = 1564 Score = 38.1 bits (87), Expect = 0.037 Identities = 46/165 (27%), Positives = 61/165 (36%), Gaps = 14/165 (8%) Query: 12 SSPAQRRRGNDPLTSSPGRSSRRTDALTSSPGRDLPPFEDESEGLLGTEGPLEEEEDGEE 71 SSP + + ND L R RR D + + E E E E E D E Sbjct: 642 SSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDRER 701 Query: 72 LIGDGMERDYRAIPELDAYEAEGLALDDEDVEELTASQREAAERAMRQRDREAGRGLGRM 131 +ER+ RA E E D D + +RE R+RDRE R R Sbjct: 702 EKERELERE-RAREREREREKERDRERDRDRDHDRERERE------RERDREKERERERE 754 Query: 132 RRGLLYDSDEEDEERPARKRRQVERATEDGEEDEEMIESIENLED 176 R E + ER + R+ ER E E ++ E + ED Sbjct: 755 ER-------ERERERERERERERERERERARERDKERERQRDWED 792 >gi|6005757 chromatin-specific transcription elongation factor large subunit [Homo sapiens] Length = 1047 Score = 37.7 bits (86), Expect = 0.049 Identities = 30/120 (25%), Positives = 51/120 (42%), Gaps = 12/120 (10%) Query: 43 GRDLPPFEDESEGLLGTEGPLEEEEDGEELIGDGMERDYRAIPELDAYEAEGLALDDE-- 100 G D + ESE T P E++ + EE + + DY + E Y E L ++E Sbjct: 931 GSDAEEGDSESEIEDETFNPSEDDYEEEE---EDSDEDYSSEAEESDYSKESLGSEEESG 987 Query: 101 -DVEELTASQREAAERAMRQRDREAGRGLGRMRRGLLYDS------DEEDEERPARKRRQ 153 D +EL R+A + + + E R + R R+ ++ S P +K+R+ Sbjct: 988 KDWDELEEEARKADRESRYEEEEEQSRSMSRKRKASVHSSGRGSNRGSRHSSAPPKKKRK 1047 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.134 0.380 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 33,781,411 Number of Sequences: 37866 Number of extensions: 1594834 Number of successful extensions: 8926 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 42 Number of HSP's successfully gapped in prelim test: 222 Number of HSP's that attempted gapping in prelim test: 7684 Number of HSP's gapped (non-prelim): 1049 length of query: 904 length of database: 18,247,518 effective HSP length: 111 effective length of query: 793 effective length of database: 14,044,392 effective search space: 11137202856 effective search space used: 11137202856 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.