Search of human proteins with 12408658

Search of human proteins with 12408658

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|12408658 cell division cycle 25C isoform b [Homo sapiens]
         (400 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|12408658 cell division cycle 25C isoform b [Homo sapiens]          816   0.0  
gi|125625350 cell division cycle 25C isoform a [Homo sapiens]         660   0.0  
gi|11641413 cell division cycle 25B isoform 1 [Homo sapiens]          263   2e-70
gi|11641411 cell division cycle 25B isoform 3 [Homo sapiens]          263   2e-70
gi|4757950 cell division cycle 25B isoform 2 [Homo sapiens]           263   2e-70
gi|42490760 cell division cycle 25A isoform b [Homo sapiens]          255   4e-68
gi|42490758 cell division cycle 25A isoform a [Homo sapiens]          255   4e-68
gi|7019493 DNA-directed DNA polymerase mu [Homo sapiens]               36   0.070
gi|95147555 microtubule-associated protein 1A [Homo sapiens]           36   0.070
gi|62865890 dual specificity phosphatase 5 [Homo sapiens]              34   0.27 
gi|34328899 protein tyrosine phosphatase, non-receptor type 14 [...    33   0.46 
gi|148806928 hypothetical protein LOC57482 [Homo sapiens]              33   0.60 
gi|217035118 TBC1 domain family, member 23 [Homo sapiens]              32   1.3  
gi|154146191 heat shock 90kDa protein 1, alpha isoform 2 [Homo s...    30   3.0  
gi|153792590 heat shock 90kDa protein 1, alpha isoform 1 [Homo s...    30   3.0  
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    30   3.0  
gi|20149594 heat shock 90kDa protein 1, beta [Homo sapiens]            30   3.0  
gi|90652857 hypothetical protein LOC84904 [Homo sapiens]               30   3.0  
gi|4885579 RCD1 required for cell differentiation1 homolog [Homo...    30   5.0  
gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens]     30   5.0  
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ...    30   5.0  
gi|22095388 islet cell autoantigen 1,69kDa-like isoform 1 [Homo ...    30   5.0  
gi|197313732 pleckstrin homology-like domain, family B, member 2...    29   6.6  
gi|197313730 pleckstrin homology-like domain, family B, member 2...    29   6.6  

>gi|12408658 cell division cycle 25C isoform b [Homo sapiens]
          Length = 400

 Score =  816 bits (2108), Expect = 0.0
 Identities = 400/400 (100%), Positives = 400/400 (100%)

Query: 1   MSTELFSSTREEGSSGSGPSFRSNQRKMLNLLLERDTSFTVCPDVPRTPVGKFLGDSANL 60
           MSTELFSSTREEGSSGSGPSFRSNQRKMLNLLLERDTSFTVCPDVPRTPVGKFLGDSANL
Sbjct: 1   MSTELFSSTREEGSSGSGPSFRSNQRKMLNLLLERDTSFTVCPDVPRTPVGKFLGDSANL 60

Query: 61  SILSGSPGFFRTSGSAFSWDDNGNLVDSEMKYLGSPITTVPKLDKNPNLGEDQAEEISDE 120
           SILSGSPGFFRTSGSAFSWDDNGNLVDSEMKYLGSPITTVPKLDKNPNLGEDQAEEISDE
Sbjct: 61  SILSGSPGFFRTSGSAFSWDDNGNLVDSEMKYLGSPITTVPKLDKNPNLGEDQAEEISDE 120

Query: 121 LMEFSLKDQEAKVSRSGLYRSPSMPENLNRPRLKQVEKFKDNTIPDKVKKKYFSGQGKLR 180
           LMEFSLKDQEAKVSRSGLYRSPSMPENLNRPRLKQVEKFKDNTIPDKVKKKYFSGQGKLR
Sbjct: 121 LMEFSLKDQEAKVSRSGLYRSPSMPENLNRPRLKQVEKFKDNTIPDKVKKKYFSGQGKLR 180

Query: 181 KGLCLKKTVSLCDITITQMLEEDSNQGHLIGDFSKVCALPTVSGKHQDLKYVNPETVAAL 240
           KGLCLKKTVSLCDITITQMLEEDSNQGHLIGDFSKVCALPTVSGKHQDLKYVNPETVAAL
Sbjct: 181 KGLCLKKTVSLCDITITQMLEEDSNQGHLIGDFSKVCALPTVSGKHQDLKYVNPETVAAL 240

Query: 241 LSGKFQGLIEKFYVIDCRYPYEYLGGHIQGALNLYSQEELFNFFLKKPIVPLDTQKRIII 300
           LSGKFQGLIEKFYVIDCRYPYEYLGGHIQGALNLYSQEELFNFFLKKPIVPLDTQKRIII
Sbjct: 241 LSGKFQGLIEKFYVIDCRYPYEYLGGHIQGALNLYSQEELFNFFLKKPIVPLDTQKRIII 300

Query: 301 VFHCEFSSERGPRMCRCLREEDRSLNQYPALYYPELYILKGGYRDFFPEYMELCEPQSYC 360
           VFHCEFSSERGPRMCRCLREEDRSLNQYPALYYPELYILKGGYRDFFPEYMELCEPQSYC
Sbjct: 301 VFHCEFSSERGPRMCRCLREEDRSLNQYPALYYPELYILKGGYRDFFPEYMELCEPQSYC 360

Query: 361 PMHHQDHKTELLRCRSQSKVQEGERQLREQIALLVKDMSP 400
           PMHHQDHKTELLRCRSQSKVQEGERQLREQIALLVKDMSP
Sbjct: 361 PMHHQDHKTELLRCRSQSKVQEGERQLREQIALLVKDMSP 400


>gi|125625350 cell division cycle 25C isoform a [Homo sapiens]
          Length = 473

 Score =  660 bits (1703), Expect = 0.0
 Identities = 323/328 (98%), Positives = 324/328 (98%)

Query: 73  SGSAFSWDDNGNLVDSEMKYLGSPITTVPKLDKNPNLGEDQAEEISDELMEFSLKDQEAK 132
           S SA   +DNGNLVDSEMKYLGSPITTVPKLDKNPNLGEDQAEEISDELMEFSLKDQEAK
Sbjct: 146 SSSANKENDNGNLVDSEMKYLGSPITTVPKLDKNPNLGEDQAEEISDELMEFSLKDQEAK 205

Query: 133 VSRSGLYRSPSMPENLNRPRLKQVEKFKDNTIPDKVKKKYFSGQGKLRKGLCLKKTVSLC 192
           VSRSGLYRSPSMPENLNRPRLKQVEKFKDNTIPDKVKKKYFSGQGKLRKGLCLKKTVSLC
Sbjct: 206 VSRSGLYRSPSMPENLNRPRLKQVEKFKDNTIPDKVKKKYFSGQGKLRKGLCLKKTVSLC 265

Query: 193 DITITQMLEEDSNQGHLIGDFSKVCALPTVSGKHQDLKYVNPETVAALLSGKFQGLIEKF 252
           DITITQMLEEDSNQGHLIGDFSKVCALPTVSGKHQDLKYVNPETVAALLSGKFQGLIEKF
Sbjct: 266 DITITQMLEEDSNQGHLIGDFSKVCALPTVSGKHQDLKYVNPETVAALLSGKFQGLIEKF 325

Query: 253 YVIDCRYPYEYLGGHIQGALNLYSQEELFNFFLKKPIVPLDTQKRIIIVFHCEFSSERGP 312
           YVIDCRYPYEYLGGHIQGALNLYSQEELFNFFLKKPIVPLDTQKRIIIVFHCEFSSERGP
Sbjct: 326 YVIDCRYPYEYLGGHIQGALNLYSQEELFNFFLKKPIVPLDTQKRIIIVFHCEFSSERGP 385

Query: 313 RMCRCLREEDRSLNQYPALYYPELYILKGGYRDFFPEYMELCEPQSYCPMHHQDHKTELL 372
           RMCRCLREEDRSLNQYPALYYPELYILKGGYRDFFPEYMELCEPQSYCPMHHQDHKTELL
Sbjct: 386 RMCRCLREEDRSLNQYPALYYPELYILKGGYRDFFPEYMELCEPQSYCPMHHQDHKTELL 445

Query: 373 RCRSQSKVQEGERQLREQIALLVKDMSP 400
           RCRSQSKVQEGERQLREQIALLVKDMSP
Sbjct: 446 RCRSQSKVQEGERQLREQIALLVKDMSP 473



 Score =  134 bits (336), Expect = 2e-31
 Identities = 76/117 (64%), Positives = 84/117 (71%), Gaps = 10/117 (8%)

Query: 1   MSTELFSSTREEGSSGSGPSFRSNQRKMLNLLLERDTSFTVCPDVPRTPVGKFLGDSANL 60
           MSTELFSSTREEGSSGSGPSFRSNQRKMLNLLLERDTSFTVCPDVPRTPVGKFLGDSANL
Sbjct: 1   MSTELFSSTREEGSSGSGPSFRSNQRKMLNLLLERDTSFTVCPDVPRTPVGKFLGDSANL 60

Query: 61  SILSGSPGFFRTSGSAFSWDDNGNLVDSEMKYLGSPITTVPKLDKNPNLGEDQAEEI 117
           SILSG        G+     D  NL   E+    + +TT   LD+  +L     +E+
Sbjct: 61  SILSG--------GTPKRCLDLSNLSSGEI--TATQLTTSADLDETGHLDSSGLQEV 107


>gi|11641413 cell division cycle 25B isoform 1 [Homo sapiens]
          Length = 580

 Score =  263 bits (672), Expect = 2e-70
 Identities = 129/258 (50%), Positives = 177/258 (68%), Gaps = 9/258 (3%)

Query: 138 LYRSPSMPENLNRPRLKQVEKFKDNTIPDKVKKKYF------SGQGKLRKGLCLKKTVSL 191
           L+RSPSMP ++ RP LK++E+ +D   P + K++          + +  K   L+   SL
Sbjct: 318 LFRSPSMPCSVIRPILKRLERPQDRDTPVQNKRRRSVTPPEEQQEAEEPKARVLRSK-SL 376

Query: 192 CDITITQMLEEDSNQGHLIGDFSKVCALPTVSGKHQDLKYVNPETVAALLSGKFQGLIEK 251
           C   I  +L+ D  +  LIGD+SK   L TV GKHQDLKY++PET+ ALL+GKF  +++K
Sbjct: 377 CHDEIENLLDSDHRE--LIGDYSKAFLLQTVDGKHQDLKYISPETMVALLTGKFSNIVDK 434

Query: 252 FYVIDCRYPYEYLGGHIQGALNLYSQEELFNFFLKKPIVPLDTQKRIIIVFHCEFSSERG 311
           F ++DCRYPYEY GGHI+ A+NL  + +  +F LK PI P    KR+I++FHCEFSSERG
Sbjct: 435 FVIVDCRYPYEYEGGHIKTAVNLPLERDAESFLLKSPIAPCSLDKRVILIFHCEFSSERG 494

Query: 312 PRMCRCLREEDRSLNQYPALYYPELYILKGGYRDFFPEYMELCEPQSYCPMHHQDHKTEL 371
           PRMCR +RE DR++N YP+LYYPE+YILKGGY++FFP++   CEPQ Y PM+H+  K EL
Sbjct: 495 PRMCRFIRERDRAVNDYPSLYYPEMYILKGGYKEFFPQHPNFCEPQDYRPMNHEAFKDEL 554

Query: 372 LRCRSQSKVQEGERQLRE 389
              R +++   GER  RE
Sbjct: 555 KTFRLKTRSWAGERSRRE 572


>gi|11641411 cell division cycle 25B isoform 3 [Homo sapiens]
          Length = 539

 Score =  263 bits (672), Expect = 2e-70
 Identities = 129/258 (50%), Positives = 177/258 (68%), Gaps = 9/258 (3%)

Query: 138 LYRSPSMPENLNRPRLKQVEKFKDNTIPDKVKKKYF------SGQGKLRKGLCLKKTVSL 191
           L+RSPSMP ++ RP LK++E+ +D   P + K++          + +  K   L+   SL
Sbjct: 277 LFRSPSMPCSVIRPILKRLERPQDRDTPVQNKRRRSVTPPEEQQEAEEPKARVLRSK-SL 335

Query: 192 CDITITQMLEEDSNQGHLIGDFSKVCALPTVSGKHQDLKYVNPETVAALLSGKFQGLIEK 251
           C   I  +L+ D  +  LIGD+SK   L TV GKHQDLKY++PET+ ALL+GKF  +++K
Sbjct: 336 CHDEIENLLDSDHRE--LIGDYSKAFLLQTVDGKHQDLKYISPETMVALLTGKFSNIVDK 393

Query: 252 FYVIDCRYPYEYLGGHIQGALNLYSQEELFNFFLKKPIVPLDTQKRIIIVFHCEFSSERG 311
           F ++DCRYPYEY GGHI+ A+NL  + +  +F LK PI P    KR+I++FHCEFSSERG
Sbjct: 394 FVIVDCRYPYEYEGGHIKTAVNLPLERDAESFLLKSPIAPCSLDKRVILIFHCEFSSERG 453

Query: 312 PRMCRCLREEDRSLNQYPALYYPELYILKGGYRDFFPEYMELCEPQSYCPMHHQDHKTEL 371
           PRMCR +RE DR++N YP+LYYPE+YILKGGY++FFP++   CEPQ Y PM+H+  K EL
Sbjct: 454 PRMCRFIRERDRAVNDYPSLYYPEMYILKGGYKEFFPQHPNFCEPQDYRPMNHEAFKDEL 513

Query: 372 LRCRSQSKVQEGERQLRE 389
              R +++   GER  RE
Sbjct: 514 KTFRLKTRSWAGERSRRE 531


>gi|4757950 cell division cycle 25B isoform 2 [Homo sapiens]
          Length = 566

 Score =  263 bits (672), Expect = 2e-70
 Identities = 129/258 (50%), Positives = 177/258 (68%), Gaps = 9/258 (3%)

Query: 138 LYRSPSMPENLNRPRLKQVEKFKDNTIPDKVKKKYF------SGQGKLRKGLCLKKTVSL 191
           L+RSPSMP ++ RP LK++E+ +D   P + K++          + +  K   L+   SL
Sbjct: 304 LFRSPSMPCSVIRPILKRLERPQDRDTPVQNKRRRSVTPPEEQQEAEEPKARVLRSK-SL 362

Query: 192 CDITITQMLEEDSNQGHLIGDFSKVCALPTVSGKHQDLKYVNPETVAALLSGKFQGLIEK 251
           C   I  +L+ D  +  LIGD+SK   L TV GKHQDLKY++PET+ ALL+GKF  +++K
Sbjct: 363 CHDEIENLLDSDHRE--LIGDYSKAFLLQTVDGKHQDLKYISPETMVALLTGKFSNIVDK 420

Query: 252 FYVIDCRYPYEYLGGHIQGALNLYSQEELFNFFLKKPIVPLDTQKRIIIVFHCEFSSERG 311
           F ++DCRYPYEY GGHI+ A+NL  + +  +F LK PI P    KR+I++FHCEFSSERG
Sbjct: 421 FVIVDCRYPYEYEGGHIKTAVNLPLERDAESFLLKSPIAPCSLDKRVILIFHCEFSSERG 480

Query: 312 PRMCRCLREEDRSLNQYPALYYPELYILKGGYRDFFPEYMELCEPQSYCPMHHQDHKTEL 371
           PRMCR +RE DR++N YP+LYYPE+YILKGGY++FFP++   CEPQ Y PM+H+  K EL
Sbjct: 481 PRMCRFIRERDRAVNDYPSLYYPEMYILKGGYKEFFPQHPNFCEPQDYRPMNHEAFKDEL 540

Query: 372 LRCRSQSKVQEGERQLRE 389
              R +++   GER  RE
Sbjct: 541 KTFRLKTRSWAGERSRRE 558


>gi|42490760 cell division cycle 25A isoform b [Homo sapiens]
          Length = 484

 Score =  255 bits (652), Expect = 4e-68
 Identities = 132/273 (48%), Positives = 183/273 (67%), Gaps = 13/273 (4%)

Query: 134 SRSGLYRSPSMPENLNRPRLKQVEKFKDNTIPDKVKKKYFSGQGKLRKGL-------CLK 186
           +R  L+ SPS+  +  R  LK+ E+ ++ + P   K++        ++          L 
Sbjct: 214 NRCKLFDSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGASPKESTNPEKAHETLH 273

Query: 187 KTVSLCDI---TITQMLEEDSNQGHLIGDFSKVCALPTVSGKHQDLKYVNPETVAALLSG 243
           +++SL      TI  +L+ D     LIGDFSK     TV+GKHQDLKY++PE +A++L+G
Sbjct: 274 QSLSLASSPKGTIENILDNDPRD--LIGDFSKGYLFHTVAGKHQDLKYISPEIMASVLNG 331

Query: 244 KFQGLIEKFYVIDCRYPYEYLGGHIQGALNLYSQEELFNFFLKKPIVPLDTQKRIIIVFH 303
           KF  LI++F +IDCRYPYEY GGHI+GA+NL+ +EE+ +F LKKPIVP D  KR+I+VFH
Sbjct: 332 KFANLIKEFVIIDCRYPYEYEGGHIKGAVNLHMEEEVEDFLLKKPIVPTDG-KRVIVVFH 390

Query: 304 CEFSSERGPRMCRCLREEDRSLNQYPALYYPELYILKGGYRDFFPEYMELCEPQSYCPMH 363
           CEFSSERGPRMCR +RE DR  N+YP L+YPELY+LKGGY++FF +    CEP SY PMH
Sbjct: 391 CEFSSERGPRMCRYVRERDRLGNEYPKLHYPELYVLKGGYKEFFMKCQSYCEPPSYRPMH 450

Query: 364 HQDHKTELLRCRSQSKVQEGERQLREQIALLVK 396
           H+D K +L + R++S+   GE+  RE  + L K
Sbjct: 451 HEDFKEDLKKFRTKSRTWAGEKSKREMYSRLKK 483


>gi|42490758 cell division cycle 25A isoform a [Homo sapiens]
          Length = 524

 Score =  255 bits (652), Expect = 4e-68
 Identities = 132/273 (48%), Positives = 183/273 (67%), Gaps = 13/273 (4%)

Query: 134 SRSGLYRSPSMPENLNRPRLKQVEKFKDNTIPDKVKKKYFSGQGKLRKGL-------CLK 186
           +R  L+ SPS+  +  R  LK+ E+ ++ + P   K++        ++          L 
Sbjct: 254 NRCKLFDSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGASPKESTNPEKAHETLH 313

Query: 187 KTVSLCDI---TITQMLEEDSNQGHLIGDFSKVCALPTVSGKHQDLKYVNPETVAALLSG 243
           +++SL      TI  +L+ D     LIGDFSK     TV+GKHQDLKY++PE +A++L+G
Sbjct: 314 QSLSLASSPKGTIENILDNDPRD--LIGDFSKGYLFHTVAGKHQDLKYISPEIMASVLNG 371

Query: 244 KFQGLIEKFYVIDCRYPYEYLGGHIQGALNLYSQEELFNFFLKKPIVPLDTQKRIIIVFH 303
           KF  LI++F +IDCRYPYEY GGHI+GA+NL+ +EE+ +F LKKPIVP D  KR+I+VFH
Sbjct: 372 KFANLIKEFVIIDCRYPYEYEGGHIKGAVNLHMEEEVEDFLLKKPIVPTDG-KRVIVVFH 430

Query: 304 CEFSSERGPRMCRCLREEDRSLNQYPALYYPELYILKGGYRDFFPEYMELCEPQSYCPMH 363
           CEFSSERGPRMCR +RE DR  N+YP L+YPELY+LKGGY++FF +    CEP SY PMH
Sbjct: 431 CEFSSERGPRMCRYVRERDRLGNEYPKLHYPELYVLKGGYKEFFMKCQSYCEPPSYRPMH 490

Query: 364 HQDHKTELLRCRSQSKVQEGERQLREQIALLVK 396
           H+D K +L + R++S+   GE+  RE  + L K
Sbjct: 491 HEDFKEDLKKFRTKSRTWAGEKSKREMYSRLKK 523


>gi|7019493 DNA-directed DNA polymerase mu [Homo sapiens]
          Length = 494

 Score = 35.8 bits (81), Expect = 0.070
 Identities = 25/87 (28%), Positives = 46/87 (52%), Gaps = 5/87 (5%)

Query: 55  GDSANLSILSGSPGFFRTSGSAFSWDDNGNLVDSEMKYLGSPITTVPKLDKNPNLGEDQA 114
           G S  L IL+ + GF  + G   ++    ++    +K L SP+TT+ +L   P+ GE  +
Sbjct: 155 GLSEALEILAEAAGFEGSEGRLLTFCRAASV----LKALPSPVTTLSQLQGLPHFGE-HS 209

Query: 115 EEISDELMEFSLKDQEAKVSRSGLYRS 141
             +  EL+E  + ++  +V RS  Y++
Sbjct: 210 SRVVQELLEHGVCEEVERVRRSERYQT 236


>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
          Length = 2803

 Score = 35.8 bits (81), Expect = 0.070
 Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 1/87 (1%)

Query: 87  DSEMKYLGSPITTVPKLDKNPNLGEDQAEEISDELM-EFSLKDQEAKVSRSGLYRSPSMP 145
           DS+     +  T V KL K   + E+ A+E   EL  E +  +++AK S       P+ P
Sbjct: 318 DSKESLKATTKTAVSKLAKREEVVEEGAKEARSELAKELAKTEKKAKESSEKPPEKPAKP 377

Query: 146 ENLNRPRLKQVEKFKDNTIPDKVKKKY 172
           E +     + ++  K   I DKV KK+
Sbjct: 378 ERVKTESSEALKAEKRKLIKDKVGKKH 404


>gi|62865890 dual specificity phosphatase 5 [Homo sapiens]
          Length = 384

 Score = 33.9 bits (76), Expect = 0.27
 Identities = 19/51 (37%), Positives = 26/51 (50%), Gaps = 5/51 (9%)

Query: 309 ERGPRMCRCLREEDRSLNQYPALYY-----PELYILKGGYRDFFPEYMELC 354
           ++G R  + LREE  +     +L       P +Y LKGGY  F+ EY E C
Sbjct: 90  DQGSRHWQKLREESAARVVLTSLLACLPAGPRVYFLKGGYETFYSEYPECC 140


>gi|34328899 protein tyrosine phosphatase, non-receptor type 14
           [Homo sapiens]
          Length = 1187

 Score = 33.1 bits (74), Expect = 0.46
 Identities = 13/46 (28%), Positives = 29/46 (63%)

Query: 119 DELMEFSLKDQEAKVSRSGLYRSPSMPENLNRPRLKQVEKFKDNTI 164
           +E M F+  +Q  K   +G++ + ++PEN  R R+++V  +++N +
Sbjct: 905 EEGMVFTEYEQIPKKKANGIFSTAALPENAERSRIREVVPYEENRV 950


>gi|148806928 hypothetical protein LOC57482 [Homo sapiens]
          Length = 1233

 Score = 32.7 bits (73), Expect = 0.60
 Identities = 24/63 (38%), Positives = 39/63 (61%), Gaps = 8/63 (12%)

Query: 113  QAEEISDELMEFSLKDQEAKVSRSG-LYRSPSMPENLNRP-----RLKQVEKFKD-NTIP 165
            QAE++S E +  S++   + VSR+G L++S ++PE   RP     RL++ E+ K  NT+P
Sbjct: 1118 QAEKLSKENVSVSVQPGSSSVSRAGSLHKSTALPEE-KRPETAVSRLERREQLKKANTLP 1176

Query: 166  DKV 168
              V
Sbjct: 1177 TSV 1179


>gi|217035118 TBC1 domain family, member 23 [Homo sapiens]
          Length = 684

 Score = 31.6 bits (70), Expect = 1.3
 Identities = 16/43 (37%), Positives = 24/43 (55%)

Query: 240 LLSGKFQGLIEKFYVIDCRYPYEYLGGHIQGALNLYSQEELFN 282
           L + + QG   +F+V+DCR   +Y  GH+  A +L S   L N
Sbjct: 326 LQANQLQGEGVRFFVVDCRPAEQYNAGHLSTAFHLDSDLMLQN 368


>gi|154146191 heat shock 90kDa protein 1, alpha isoform 2 [Homo
           sapiens]
          Length = 732

 Score = 30.4 bits (67), Expect = 3.0
 Identities = 26/104 (25%), Positives = 49/104 (47%), Gaps = 24/104 (23%)

Query: 85  LVDSEMKYLGSPITTVPKLDKNPNLGEDQAEEISDELMEFSLKDQEAKVSRSGLYRSPSM 144
           +V    +++G PIT   + +++  + +D+AEE  D+  E   K++E K            
Sbjct: 206 IVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEE---KEKEEK------------ 250

Query: 145 PENLNRPRLKQV-------EKFKDNTIPDKVKKKYFSGQGKLRK 181
            E+ ++P ++ V       +K  D     K+K+KY   Q +L K
Sbjct: 251 -ESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYID-QEELNK 292


>gi|153792590 heat shock 90kDa protein 1, alpha isoform 1 [Homo
           sapiens]
          Length = 854

 Score = 30.4 bits (67), Expect = 3.0
 Identities = 26/104 (25%), Positives = 49/104 (47%), Gaps = 24/104 (23%)

Query: 85  LVDSEMKYLGSPITTVPKLDKNPNLGEDQAEEISDELMEFSLKDQEAKVSRSGLYRSPSM 144
           +V    +++G PIT   + +++  + +D+AEE  D+  E   K++E K            
Sbjct: 328 IVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEE---KEKEEK------------ 372

Query: 145 PENLNRPRLKQV-------EKFKDNTIPDKVKKKYFSGQGKLRK 181
            E+ ++P ++ V       +K  D     K+K+KY   Q +L K
Sbjct: 373 -ESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYID-QEELNK 414


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 30.4 bits (67), Expect = 3.0
 Identities = 32/122 (26%), Positives = 46/122 (37%), Gaps = 5/122 (4%)

Query: 52  KFLGDSANLSILSGSPGFFRTSGSAFSWDDNGNLVDSEMKYLGSPITTVPKLDKNPNLGE 111
           K  G +A     S   G   +S S+ S DD+    + ++K  GSP    PK +    L  
Sbjct: 496 KVAGGAAPSKPASAKKGKAESSNSSSS-DDSSEEEEEKLKGKGSPRPQAPKANGTSALTA 554

Query: 112 DQAEEI-SDELMEFSLKDQEAKVSRSGLYRSPSMPENLNRPRLKQVEKFK---DNTIPDK 167
              +   + E  E   K     VS+SG  +     E        Q +K K    NT P +
Sbjct: 555 QNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQAKKIKLQTPNTFPKR 614

Query: 168 VK 169
            K
Sbjct: 615 KK 616


>gi|20149594 heat shock 90kDa protein 1, beta [Homo sapiens]
          Length = 724

 Score = 30.4 bits (67), Expect = 3.0
 Identities = 21/86 (24%), Positives = 38/86 (44%), Gaps = 1/86 (1%)

Query: 85  LVDSEMKYLGSPITTVPKLDKNPNLGEDQAEEISDELMEFSLKDQE-AKVSRSGLYRSPS 143
           +V    +++G PIT   + ++   + +D+AEE   E  E    D+E  K+   G      
Sbjct: 201 VVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDD 260

Query: 144 MPENLNRPRLKQVEKFKDNTIPDKVK 169
             ++  +   K  EK+ D    +K K
Sbjct: 261 SGKDKKKKTKKIKEKYIDQEELNKTK 286


>gi|90652857 hypothetical protein LOC84904 [Homo sapiens]
          Length = 335

 Score = 30.4 bits (67), Expect = 3.0
 Identities = 16/44 (36%), Positives = 25/44 (56%)

Query: 351 MELCEPQSYCPMHHQDHKTELLRCRSQSKVQEGERQLREQIALL 394
           MEL  P S CP+  Q  + E  R  +  ++ E ER+ +EQ+ L+
Sbjct: 1   MELSCPGSRCPVQEQRARWERKRACTARELLETERRYQEQLGLV 44


>gi|4885579 RCD1 required for cell differentiation1 homolog [Homo
           sapiens]
          Length = 299

 Score = 29.6 bits (65), Expect = 5.0
 Identities = 20/64 (31%), Positives = 32/64 (50%), Gaps = 4/64 (6%)

Query: 233 NPETVAALLSGKFQGLIEKF-YVIDCRYPYEYL---GGHIQGALNLYSQEELFNFFLKKP 288
           +PET +A L+      +  F + +    P+EYL      + GAL    ++E+ NF L   
Sbjct: 103 HPETRSAFLAAHIPLFLYPFLHTVSKTRPFEYLRLTSLGVIGALVKTDEQEVINFLLTTE 162

Query: 289 IVPL 292
           I+PL
Sbjct: 163 IIPL 166


>gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens]
          Length = 394

 Score = 29.6 bits (65), Expect = 5.0
 Identities = 32/121 (26%), Positives = 50/121 (41%), Gaps = 23/121 (19%)

Query: 251 KFYVIDCRYPYEYLGGHIQGALNLYS----QEELFNFFLKKPIVPLDTQKRI-------- 298
           K  ++DCR    +  G+I G++N+      +         + I+P + + R         
Sbjct: 44  KCLLLDCRPFLAHSAGYILGSVNVRCNTIVRRRAKGSVSLEQILPAEEEVRARLRSGLYS 103

Query: 299 -IIVFHCEFSSERGPRMCRCLREEDRSLNQYPALYY----PELYILKGGYRDFFPEYMEL 353
            +IV+      ER PR    LRE+        AL       ++ +LKGGY  F  EY E 
Sbjct: 104 AVIVY-----DERSPR-AESLREDSTVSLVVQALRRNAERTDICLLKGGYERFSSEYPEF 157

Query: 354 C 354
           C
Sbjct: 158 C 158


>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
            transmembrane signal), 1 [Homo sapiens]
          Length = 3259

 Score = 29.6 bits (65), Expect = 5.0
 Identities = 46/237 (19%), Positives = 95/237 (40%), Gaps = 35/237 (14%)

Query: 80   DDNGNLVDSEMKYLGSPITTVPKLDKNPNLGEDQAEEISDELMEFSLKDQEAKVSRSGLY 139
            DD   ++D   K+       +   ++   L ED    + D+L + S+  +E K++ S L 
Sbjct: 2199 DDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLE 2258

Query: 140  RSPSMPENLNRPRLKQVEKFKDN---------TIPDKVKKKYFSGQGKLRKGLCLKKTVS 190
                + E+  +  ++  +K  D          +  ++ +  Y S Q +L K     K++ 
Sbjct: 2259 HDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLK 2318

Query: 191  LCDITITQMLEEDSNQ-GHLIG-------------------DFSKVCALPTVSGKHQDLK 230
                 ++  LE+   Q G+L G                   +     +    S  H+++ 
Sbjct: 2319 DQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEIN 2378

Query: 231  YVNPETVAALLSGKFQGLIEKFYVIDCRYPYEYLGGHIQGALNLYSQEELFNFFLKK 287
             +  + + +LLSGK + +  +  + + R  ++     I+   NL SQEE  N  L++
Sbjct: 2379 -MKEQKIISLLSGKEEAI--QVAIAELRQQHD---KEIKELENLLSQEEEENIVLEE 2429


>gi|22095388 islet cell autoantigen 1,69kDa-like isoform 1 [Homo
           sapiens]
          Length = 482

 Score = 29.6 bits (65), Expect = 5.0
 Identities = 28/105 (26%), Positives = 45/105 (42%), Gaps = 7/105 (6%)

Query: 117 ISDELMEFSLKDQEAKVSRSGLYRSPSMPENLNRPRLKQVEKFKDNTIPDKVKKKYFSGQ 176
           +SD LM  +  +Q     R  L     + + L+   LKQ+EKF+   +  +  K  F   
Sbjct: 142 VSDTLMTINRMEQARTEYRGALLWMKDVSQELDPDTLKQMEKFRKVQMQVRNSKASFD-- 199

Query: 177 GKLRKGLCLKKTVSLCDITITQMLEED--SNQGHLIGDFSKVCAL 219
            KL+  +C K  V L   +   ML     + Q  L+G + K   +
Sbjct: 200 -KLKMDVCQK--VDLLGASRCNMLSHSLTTYQRTLLGFWKKTARM 241


>gi|197313732 pleckstrin homology-like domain, family B, member 2
           isoform a [Homo sapiens]
          Length = 1253

 Score = 29.3 bits (64), Expect = 6.6
 Identities = 34/139 (24%), Positives = 63/139 (45%), Gaps = 18/139 (12%)

Query: 37  TSFTVCPDVPRTPVGKFLGDSANLSILSGSPGFF---RTSGSAFSWDDNGNLVDSEMKYL 93
           +  T  P  P +   K   +S+ LSIL  +P      + S    + ++   ++ + ++ L
Sbjct: 545 SDLTRTPPPPSSTFPKASSESSYLSILPKTPEGISEEQRSQELAAMEETRIVILNNLEEL 604

Query: 94  GSPITTVPKLDKNPNLGEDQAEEISDEL-MEFSLKDQEAKVSRSGLYRSPSMPENLNRPR 152
              I  +           DQ +E   EL ME +L D E K   + L +   + ++LNR +
Sbjct: 605 KQKIKDI----------NDQMDESFRELDMECALLDGEQKSETTELMKEKEILDHLNR-K 653

Query: 153 LKQVEKFKDNTIPDKVKKK 171
           + ++EK   N + +K K+K
Sbjct: 654 IAELEK---NIVGEKTKEK 669


>gi|197313730 pleckstrin homology-like domain, family B, member 2
           isoform a [Homo sapiens]
          Length = 1253

 Score = 29.3 bits (64), Expect = 6.6
 Identities = 34/139 (24%), Positives = 63/139 (45%), Gaps = 18/139 (12%)

Query: 37  TSFTVCPDVPRTPVGKFLGDSANLSILSGSPGFF---RTSGSAFSWDDNGNLVDSEMKYL 93
           +  T  P  P +   K   +S+ LSIL  +P      + S    + ++   ++ + ++ L
Sbjct: 545 SDLTRTPPPPSSTFPKASSESSYLSILPKTPEGISEEQRSQELAAMEETRIVILNNLEEL 604

Query: 94  GSPITTVPKLDKNPNLGEDQAEEISDEL-MEFSLKDQEAKVSRSGLYRSPSMPENLNRPR 152
              I  +           DQ +E   EL ME +L D E K   + L +   + ++LNR +
Sbjct: 605 KQKIKDI----------NDQMDESFRELDMECALLDGEQKSETTELMKEKEILDHLNR-K 653

Query: 153 LKQVEKFKDNTIPDKVKKK 171
           + ++EK   N + +K K+K
Sbjct: 654 IAELEK---NIVGEKTKEK 669


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.136    0.402 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,250,668
Number of Sequences: 37866
Number of extensions: 784690
Number of successful extensions: 1813
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 1787
Number of HSP's gapped (non-prelim): 30
length of query: 400
length of database: 18,247,518
effective HSP length: 104
effective length of query: 296
effective length of database: 14,309,454
effective search space: 4235598384
effective search space used: 4235598384
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.