Search of human proteins with 122939147

Search of human proteins with 122939147

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|122939147 Rho GTPase activating protein 9 isoform 1 [Homo
sapiens]
         (731 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|122939147 Rho GTPase activating protein 9 isoform 1 [Homo sap...  1488   0.0  
gi|122939151 Rho GTPase activating protein 9 isoform 2 [Homo sap...  1301   0.0  
gi|122939149 Rho GTPase activating protein 9 isoform 3 [Homo sap...  1115   0.0  
gi|188497642 ARHGAP15 [Homo sapiens]                                  331   1e-90
gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]           318   1e-86
gi|40548322 Rho GTPase activating protein 27 isoform a [Homo sap...   317   2e-86
gi|226693398 Rho GTPase activating protein 27 isoform b [Homo sa...   315   7e-86
gi|23510413 sorting nexin 26 [Homo sapiens]                           130   4e-30
gi|224458284 Rho GTPase activating protein 23 [Homo sapiens]          128   2e-29
gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens]            120   3e-27
gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens]          120   3e-27
gi|4757980 beta chimerin isoform 2 [Homo sapiens]                     119   8e-27
gi|91106928 beta chimerin isoform 1 [Homo sapiens]                    119   8e-27
gi|229094128 active breakpoint cluster region-related  protein i...   115   1e-25
gi|38679957 active breakpoint cluster region-related  protein is...   115   1e-25
gi|38679954 active breakpoint cluster region-related  protein is...   115   1e-25
gi|218083800 Rho GTPase-activating protein isoform 1 [Homo sapiens]   115   1e-25
gi|29469071 Rho GTPase-activating protein isoform 2 [Homo sapiens]    111   3e-24
gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens]        109   8e-24
gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens]        109   1e-23
gi|203097003 Rho GTPase activating protein 21 [Homo sapiens]          107   5e-23
gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo ...   103   4e-22
gi|208022687 GTPase regulator associated with the focal adhesion...   103   6e-22
gi|7662208 GTPase regulator associated with the focal adhesion k...   103   6e-22
gi|71040096 Rho GTPase activating protein 30 isoform 2 [Homo sap...   103   7e-22
gi|71040098 Rho GTPase activating protein 30 isoform 1 [Homo sap...   103   7e-22
gi|4505507 oligophrenin 1 [Homo sapiens]                              102   1e-21
gi|156071465 Rho GTPase activating protein 4 [Homo sapiens]           102   2e-21
gi|50843948 Rho GTPase activating protein 10 [Homo sapiens]           101   2e-21
gi|221307575 Rho-type GTPase-activating protein FLJ32810 [Homo s...   101   3e-21

>gi|122939147 Rho GTPase activating protein 9 isoform 1 [Homo
           sapiens]
          Length = 731

 Score = 1488 bits (3852), Expect = 0.0
 Identities = 731/731 (100%), Positives = 731/731 (100%)

Query: 1   MLSSRWWPSSWGILGLGPRSPPRGSQLCALYAFTYTGADGQQVSLAEGDRFLLLRKTNSD 60
           MLSSRWWPSSWGILGLGPRSPPRGSQLCALYAFTYTGADGQQVSLAEGDRFLLLRKTNSD
Sbjct: 1   MLSSRWWPSSWGILGLGPRSPPRGSQLCALYAFTYTGADGQQVSLAEGDRFLLLRKTNSD 60

Query: 61  WWLARRLEAPSTSRPIFVPAAYMIEESIPSQSPTTVIPGQLLWTPGPKLFHGSLEELSQA 120
           WWLARRLEAPSTSRPIFVPAAYMIEESIPSQSPTTVIPGQLLWTPGPKLFHGSLEELSQA
Sbjct: 61  WWLARRLEAPSTSRPIFVPAAYMIEESIPSQSPTTVIPGQLLWTPGPKLFHGSLEELSQA 120

Query: 121 LPSRAQASSEQPPPLPRKMCRSVSTDNLSPSLLKPFQEGPSGRSLSQEDLPSEASASTAG 180
           LPSRAQASSEQPPPLPRKMCRSVSTDNLSPSLLKPFQEGPSGRSLSQEDLPSEASASTAG
Sbjct: 121 LPSRAQASSEQPPPLPRKMCRSVSTDNLSPSLLKPFQEGPSGRSLSQEDLPSEASASTAG 180

Query: 181 PQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCK 240
           PQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCK
Sbjct: 181 PQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCK 240

Query: 241 SWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTS 300
           SWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTS
Sbjct: 241 SWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTS 300

Query: 301 QLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFY 360
           QLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFY
Sbjct: 301 QLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFY 360

Query: 361 REPPPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHE 420
           REPPPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHE
Sbjct: 361 REPPPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHE 420

Query: 421 TELRAWHRALRTVIERLDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRS 480
           TELRAWHRALRTVIERLDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRS
Sbjct: 421 TELRAWHRALRTVIERLDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRS 480

Query: 481 SIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFL 540
           SIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFL
Sbjct: 481 SIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFL 540

Query: 541 RLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDL 600
           RLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDL
Sbjct: 541 RLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDL 600

Query: 601 DSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPK 660
           DSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPK
Sbjct: 601 DSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPK 660

Query: 661 PNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPGQLVQ 720
           PNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPGQLVQ
Sbjct: 661 PNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPGQLVQ 720

Query: 721 LMLTNFTSLFP 731
           LMLTNFTSLFP
Sbjct: 721 LMLTNFTSLFP 731


>gi|122939151 Rho GTPase activating protein 9 isoform 2 [Homo
           sapiens]
          Length = 640

 Score = 1301 bits (3367), Expect = 0.0
 Identities = 639/639 (100%), Positives = 639/639 (100%)

Query: 1   MLSSRWWPSSWGILGLGPRSPPRGSQLCALYAFTYTGADGQQVSLAEGDRFLLLRKTNSD 60
           MLSSRWWPSSWGILGLGPRSPPRGSQLCALYAFTYTGADGQQVSLAEGDRFLLLRKTNSD
Sbjct: 1   MLSSRWWPSSWGILGLGPRSPPRGSQLCALYAFTYTGADGQQVSLAEGDRFLLLRKTNSD 60

Query: 61  WWLARRLEAPSTSRPIFVPAAYMIEESIPSQSPTTVIPGQLLWTPGPKLFHGSLEELSQA 120
           WWLARRLEAPSTSRPIFVPAAYMIEESIPSQSPTTVIPGQLLWTPGPKLFHGSLEELSQA
Sbjct: 61  WWLARRLEAPSTSRPIFVPAAYMIEESIPSQSPTTVIPGQLLWTPGPKLFHGSLEELSQA 120

Query: 121 LPSRAQASSEQPPPLPRKMCRSVSTDNLSPSLLKPFQEGPSGRSLSQEDLPSEASASTAG 180
           LPSRAQASSEQPPPLPRKMCRSVSTDNLSPSLLKPFQEGPSGRSLSQEDLPSEASASTAG
Sbjct: 121 LPSRAQASSEQPPPLPRKMCRSVSTDNLSPSLLKPFQEGPSGRSLSQEDLPSEASASTAG 180

Query: 181 PQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCK 240
           PQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCK
Sbjct: 181 PQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCK 240

Query: 241 SWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTS 300
           SWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTS
Sbjct: 241 SWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTS 300

Query: 301 QLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFY 360
           QLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFY
Sbjct: 301 QLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFY 360

Query: 361 REPPPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHE 420
           REPPPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHE
Sbjct: 361 REPPPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHE 420

Query: 421 TELRAWHRALRTVIERLDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRS 480
           TELRAWHRALRTVIERLDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRS
Sbjct: 421 TELRAWHRALRTVIERLDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRS 480

Query: 481 SIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFL 540
           SIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFL
Sbjct: 481 SIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFL 540

Query: 541 RLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDL 600
           RLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDL
Sbjct: 541 RLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDL 600

Query: 601 DSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAAL 639
           DSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAAL
Sbjct: 601 DSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAAL 639


>gi|122939149 Rho GTPase activating protein 9 isoform 3 [Homo
           sapiens]
          Length = 547

 Score = 1115 bits (2883), Expect = 0.0
 Identities = 547/547 (100%), Positives = 547/547 (100%)

Query: 185 MSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCKSWKP 244
           MSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCKSWKP
Sbjct: 1   MSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCKSWKP 60

Query: 245 PRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTSQLDP 304
           PRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTSQLDP
Sbjct: 61  PRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTSQLDP 120

Query: 305 PALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFYREPP 364
           PALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFYREPP
Sbjct: 121 PALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFYREPP 180

Query: 365 PTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHETELR 424
           PTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHETELR
Sbjct: 181 PTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHETELR 240

Query: 425 AWHRALRTVIERLDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRSSIRG 484
           AWHRALRTVIERLDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRSSIRG
Sbjct: 241 AWHRALRTVIERLDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRSSIRG 300

Query: 485 PEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCI 544
           PEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCI
Sbjct: 301 PEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCI 360

Query: 545 AAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTE 604
           AAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTE
Sbjct: 361 AAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTE 420

Query: 605 WDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPKPNHD 664
           WDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPKPNHD
Sbjct: 421 WDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPKPNHD 480

Query: 665 TLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPGQLVQLMLT 724
           TLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPGQLVQLMLT
Sbjct: 481 TLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPGQLVQLMLT 540

Query: 725 NFTSLFP 731
           NFTSLFP
Sbjct: 541 NFTSLFP 547


>gi|188497642 ARHGAP15 [Homo sapiens]
          Length = 475

 Score =  331 bits (849), Expect = 1e-90
 Identities = 183/428 (42%), Positives = 265/428 (61%), Gaps = 40/428 (9%)

Query: 312 PLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFYREPPPTAPSSG 371
           PL QL+     VEK G L   KIA GG+KLRKNW  SW+VL+   + FY+E    A S+ 
Sbjct: 74  PLEQLM-----VEKEGYLQKAKIADGGKKLRKNWSTSWIVLSSRRIEFYKESKQQALSNM 128

Query: 372 WGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHETELRAWHRALR 431
               G +PES VDL GA +   +  SSR+NV  I T+ G+EFLLQSD +  +  W  A++
Sbjct: 129 --KTGHKPES-VDLCGAHIEWAKEKSSRKNVFQITTVSGNEFLLQSDIDFIILDWFHAIK 185

Query: 432 TVIERLDRENP-----LEL-RLSGSGPAELSAGED---EEEESELVSKPLLRLSSRRSSI 482
             I+RL +++      LEL ++  S   EL +  D   +E++ E     + RL    S  
Sbjct: 186 NAIDRLPKDSSCPSRNLELFKIQRSSSTELLSHYDSDIKEQKPEHRKSLMFRLHHSAS-- 243

Query: 483 RGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRL 542
              + +++NRV+++LK+ I +RP L++LQE+GL++DQ+FG  L  +C+RE  TVP F++ 
Sbjct: 244 ---DTSDKNRVKSRLKKFITRRPSLKTLQEKGLIKDQIFGSHLHKVCERENSTVPWFVKQ 300

Query: 543 CIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDS 602
           CI AV+KRGLDVDGIYRVSGNLA +QKLRF+V+                  QE +L+LD 
Sbjct: 301 CIEAVEKRGLDVDGIYRVSGNLATIQKLRFIVN------------------QEEKLNLDD 342

Query: 603 TEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPKPN 662
           ++W+DIHVVTGALK+F RELP+PL P      F  A+   ++   +  ++ L+  +P PN
Sbjct: 343 SQWEDIHVVTGALKMFFRELPEPLFPYSFFEQFVEAIKKQDNNTRIEAVKSLVQKLPPPN 402

Query: 663 HDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPGQLVQLM 722
            DT++ L  HL +++A + KN M+  +LGIVFGPTL R E ET + A H +Y  Q+ +LM
Sbjct: 403 RDTMKVLFGHLTKIVAKASKNLMSTQSLGIVFGPTLLRAENETGNMAIHMVYQNQIAELM 462

Query: 723 LTNFTSLF 730
           L+ ++ +F
Sbjct: 463 LSEYSKIF 470


>gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]
          Length = 846

 Score =  318 bits (815), Expect = 1e-86
 Identities = 193/520 (37%), Positives = 302/520 (58%), Gaps = 43/520 (8%)

Query: 217 DAWEQHLDPNSGRCFYINSLTGCKSWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKG 276
           + W +H+D + GR +Y ++      W+ P+ + S      +  +++L R         K 
Sbjct: 362 EKWLKHVD-DQGRQYYYSADGSRSEWELPKYNASSQQQREIIKSRSLDRRLQEPIVLTK- 419

Query: 277 FRSDTGTPEPLDPQGSLSLSQRTSQLDPPALQAPRPLPQLLD---DPHEVEKSGLLNMTK 333
           +R  T   +  D +     S   S+   P  ++    P+  D    P + EK GLLN+TK
Sbjct: 420 WRHSTIVLDTNDKE-----SPTASKPCFPENESSPSSPKHQDTASSPKDQEKYGLLNVTK 474

Query: 334 IAQGGRKLRKNWGPSWVVLTGNSLVFYREPPPTAPSSGWGPAGSRPESSVDLRGAALAHG 393
           IA+ G+K+RKNW  SW VL G+SL+F +    +  +S +G   S+PE +VDL+GA +   
Sbjct: 475 IAENGKKVRKNWLSSWAVLQGSSLLFTKTQGSS--TSWFGSNQSKPEFTVDLKGATIEMA 532

Query: 394 -RHLSSRRNVLHIRTIPGHEFLLQSDHETELRAWHRALRTVI--ERLDRENPLELRLSGS 450
            +  SS++NV  ++T  G E L+QSD++T +  W + L + I  + ++ +  +E  +  S
Sbjct: 533 SKDKSSKKNVFELKTRQGTELLIQSDNDTVINDWFKVLSSTINNQAVETDEGIEEEIPDS 592

Query: 451 GPAELSAGEDEEEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRNKLKRLIAKRPPLQSL 510
              E    E E+++      P    S + SSI   + +EQ + +  LK+ + +RP LQ++
Sbjct: 593 PGIEKHDKEKEQKD------PKKLRSFKVSSI---DSSEQKKTKKNLKKFLTRRPTLQAV 643

Query: 511 QERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKL 570
           +E+G ++DQVFG  L +LCQRE  TVP F++LCI  V++ GLD+DGIYRVSGNLAV+QKL
Sbjct: 644 REKGYIKDQVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKL 703

Query: 571 RFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPL 630
           RF V+ +                   +LDL+ ++W+DIHV+TGALK+F RELP+PL    
Sbjct: 704 RFAVNHDE------------------KLDLNDSKWEDIHVITGALKMFFRELPEPLFTFN 745

Query: 631 LLPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNL 690
               F  A+   E  Q ++ +++LI  +PKPN DT++ L  HL RVI + +KNRMT  ++
Sbjct: 746 HFNDFVNAIK-QEPRQRVAAVKDLIRQLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSI 804

Query: 691 GIVFGPTLFRPEQETSDPAAHALYPGQLVQLMLTNFTSLF 730
            IVFGPTL +PE+ET + A H +Y  Q+V+L+L   +S+F
Sbjct: 805 AIVFGPTLLKPEKETGNIAVHTVYQNQIVELILLELSSIF 844



 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 42/122 (34%), Positives = 58/122 (47%), Gaps = 10/122 (8%)

Query: 144 STDNLSPSLLKPFQEGPSGRSLSQEDLPSEASASTAGPQPLMSEPPVYCNLVDLRRCPRS 203
           S D+      +  Q+  SG  LS     +E   +T  P     + PVY NL +L+    +
Sbjct: 198 SCDSAGEGSERIHQDSESGDELSSSS--TEQIRATTPPNQGRPDSPVYANLQELKISQSA 255

Query: 204 PPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCKSWKPPRRSRSET-------NPGS 256
            PP P  P +Q    WE H D +SGRC+Y N  T  ++WKPPR +R  +       NPG 
Sbjct: 256 LPPLPGSPAIQINGEWETHKD-SSGRCYYYNRGTQERTWKPPRWTRDASISKGDFQNPGD 314

Query: 257 ME 258
            E
Sbjct: 315 QE 316



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 18/55 (32%), Positives = 35/55 (63%), Gaps = 4/55 (7%)

Query: 31 YAFTYTGADGQQVSLAEGDRFLLLRKTNSDWWLARRLEAPSTSRPIFVPAAYMIE 85
          Y + Y   D +++ + +G+R++L++KTN DWW   +++    S+  +VPA Y+ E
Sbjct: 21 YDYEYEAKD-RKIVIKQGERYILVKKTNDDWW---QVKPDENSKAFYVPAQYVKE 71


>gi|40548322 Rho GTPase activating protein 27 isoform a [Homo
           sapiens]
          Length = 548

 Score =  317 bits (812), Expect = 2e-86
 Identities = 200/551 (36%), Positives = 295/551 (53%), Gaps = 72/551 (13%)

Query: 201 PRSPPPGPACPLLQ----------RLDAWEQHLDPNSGRCFYINSLTGCKSWKPPRRSRS 250
           P + PPG +C + Q            + W +  DP+ G+ ++ N       W+ P+    
Sbjct: 48  PLTTPPGWSCHVSQDKQMLYTNHFTQEQWVRLEDPH-GKPYFYNPEDSSVRWELPQVP-- 104

Query: 251 ETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTSQLDPPALQAP 310
                 +   +++ +++      A+    +   P  LD  GS            PA  A 
Sbjct: 105 ------VPAPRSIHKSSQDGDTPAQASPPEEKVPAELDEVGSWEEVS-------PATAAV 151

Query: 311 RPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRK-NWGPSWVVLTGNSLVFYREPPPTAPS 369
           R           ++K+G+L+ TK A  G++LRK +W  SW VL G  L F+++   +A  
Sbjct: 152 RT--------KTLDKAGVLHRTKTADKGKRLRKKHWSASWTVLEGGVLTFFKDSKTSAAG 203

Query: 370 SGWGPAG-SRPESSVDLRGAALAHG-RHLSSRRNVLHIRTIPGHEFLLQSDHETELRAWH 427
               P+  S PE +V+LRGA L+   +  SSR+NVL +R+  G E+L+Q D E  +  WH
Sbjct: 204 GLRQPSKFSTPEYTVELRGATLSWAPKDKSSRKNVLELRSRDGSEYLIQHDSEAIISTWH 263

Query: 428 RALRTVIERLDRENPLELRLS-----GSGPAELSAGEDEEEESELVSKPLLRLSSRRSSI 482
           +A+   I+ L  E P E   S     GS     S  E EE+     + P L         
Sbjct: 264 KAIAQGIQELSAELPPEESESSRVDFGSSERLGSWQEKEEDARPNAAAPAL--------- 314

Query: 483 RGPEGTEQN--RVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFL 540
            GP G E +  +VR+KL++ + +RP LQSL+E+G ++DQVFGC L +LC+RE   VP F+
Sbjct: 315 -GPVGLESDLSKVRHKLRKFLQRRPTLQSLREKGYIKDQVFGCALAALCERERSRVPRFV 373

Query: 541 RLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDL 600
           + CI AV+ RGLD+DG+YR+SGNLA +QKLR+ VD +                   RLDL
Sbjct: 374 QQCIRAVEARGLDIDGLYRISGNLATIQKLRYKVDHDE------------------RLDL 415

Query: 601 DSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPK 660
           D   W+D+HV+TGALKLF RELP+PL P      F AA+ L +  +    +++L+ S+P 
Sbjct: 416 DDGRWEDVHVITGALKLFFRELPEPLFPFSHFRQFIAAIKLQDQARRSRCVRDLVRSLPA 475

Query: 661 PNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPGQLVQ 720
           PNHDTLR L +HLCRVI H ++NRM+  ++ IVFGPTL RPE E +      ++  Q+V+
Sbjct: 476 PNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTLLRPEVEETSMPMTMVFQNQVVE 535

Query: 721 LMLTNFTSLFP 731
           L+L     +FP
Sbjct: 536 LILQQCADIFP 546


>gi|226693398 Rho GTPase activating protein 27 isoform b [Homo
           sapiens]
          Length = 521

 Score =  315 bits (808), Expect = 7e-86
 Identities = 177/419 (42%), Positives = 252/419 (60%), Gaps = 38/419 (9%)

Query: 323 VEKSGLLNMTKIAQGGRKLRK-NWGPSWVVLTGNSLVFYREPPPTAPSSGWGPAG-SRPE 380
           ++K+G+L+ TK A  G++LRK +W  SW VL G  L F+++   +A      P+  S PE
Sbjct: 129 LDKAGVLHRTKTADKGKRLRKKHWSASWTVLEGGVLTFFKDSKTSAAGGLRQPSKFSTPE 188

Query: 381 SSVDLRGAALAHG-RHLSSRRNVLHIRTIPGHEFLLQSDHETELRAWHRALRTVIERLDR 439
            +V+LRGA L+   +  SSR+NVL +R+  G E+L+Q D E  +  WH+A+   I+ L  
Sbjct: 189 YTVELRGATLSWAPKDKSSRKNVLELRSRDGSEYLIQHDSEAIISTWHKAIAQGIQELSA 248

Query: 440 ENPLELRLS-----GSGPAELSAGEDEEEESELVSKPLLRLSSRRSSIRGPEGTEQN--R 492
           E P E   S     GS     S  E EE+     + P L          GP G E +  +
Sbjct: 249 ELPPEESESSRVDFGSSERLGSWQEKEEDARPNAAAPAL----------GPVGLESDLSK 298

Query: 493 VRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGL 552
           VR+KL++ + +RP LQSL+E+G ++DQVFGC L +LC+RE   VP F++ CI AV+ RGL
Sbjct: 299 VRHKLRKFLQRRPTLQSLREKGYIKDQVFGCALAALCERERSRVPRFVQQCIRAVEARGL 358

Query: 553 DVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVT 612
           D+DG+YR+SGNLA +QKLR+ VD +                   RLDLD   W+D+HV+T
Sbjct: 359 DIDGLYRISGNLATIQKLRYKVDHDE------------------RLDLDDGRWEDVHVIT 400

Query: 613 GALKLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLEH 672
           GALKLF RELP+PL P      F AA+ L +  +    +++L+ S+P PNHDTLR L +H
Sbjct: 401 GALKLFFRELPEPLFPFSHFRQFIAAIKLQDQARRSRCVRDLVRSLPAPNHDTLRMLFQH 460

Query: 673 LCRVIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPGQLVQLMLTNFTSLFP 731
           LCRVI H ++NRM+  ++ IVFGPTL RPE E +      ++  Q+V+L+L     +FP
Sbjct: 461 LCRVIEHGEQNRMSVQSVAIVFGPTLLRPEVEETSMPMTMVFQNQVVELILQQCADIFP 519


>gi|23510413 sorting nexin 26 [Homo sapiens]
          Length = 1126

 Score =  130 bits (327), Expect = 4e-30
 Identities = 87/253 (34%), Positives = 125/253 (49%), Gaps = 23/253 (9%)

Query: 475 LSSRRSSIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGD 534
           +SS  S++  P G    ++   L+  +  RP  Q L++RG+LR +VFGC L       G 
Sbjct: 271 ISSLTSAVPRPRG----KLAGLLRTFMRSRPSRQRLRQRGILRQRVFGCDLGEHLSNSGQ 326

Query: 535 TVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQ 594
            VP  LR C   ++  G+ VDGIYR+SG  + +Q+LR   D ER          PE  G 
Sbjct: 327 DVPQVLRCCSEFIEAHGV-VDGIYRLSGVSSNIQRLRHEFDSER---------IPELSGP 376

Query: 595 EGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQEL 654
                       DIH V+   KL+ RELP PL+   L   F  A+++   E+ L ++ ++
Sbjct: 377 --------AFLQDIHSVSSLCKLYFRELPNPLLTYQLYGKFSEAMSVPGEEERLVRVHDV 428

Query: 655 IGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLFRP-EQETSDPAAHAL 713
           I  +P P++ TL YLL HL R+  HS    M   NL IV+ P L R  E E+      A 
Sbjct: 429 IQQLPPPHYRTLEYLLRHLARMARHSANTSMHARNLAIVWAPNLLRSMELESVGMGGAAA 488

Query: 714 YPGQLVQLMLTNF 726
           +    VQ ++  F
Sbjct: 489 FREVRVQSVVVEF 501


>gi|224458284 Rho GTPase activating protein 23 [Homo sapiens]
          Length = 1397

 Score =  128 bits (322), Expect = 2e-29
 Identities = 108/387 (27%), Positives = 177/387 (45%), Gaps = 39/387 (10%)

Query: 343 KNWGPSWVVLTGNSLVFY---REPPPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSR 399
           + W   +  L   SL      REP P A  +    AG    + V +    +      + R
Sbjct: 619 RQWKRVYAALRARSLSLSKERREPGPAAAGAAAAGAGEDEAAPVCIGSCLVDISYSETKR 678

Query: 400 RNVLHIRTIPGHEFLLQSDHETELRAWHRALRTVIERLDRENP-------LELRLSGSGP 452
           R+V  + T    E+L Q++   ++  W RA+R    R + E+P       +  +L+    
Sbjct: 679 RHVFRLTTADFCEYLFQAEDRDDMLGWIRAIREN-SRAEGEDPGCANQALISKKLNDYRK 737

Query: 453 AELSAGEDEEEESELVSKPLLRLSS---RRSSIRGPEGTEQNRVRNKLKRLIAKRPP--L 507
              S+G  + + S   S+ L  L S   ++S+ RG   T+     +K     A + P  +
Sbjct: 738 VSHSSGP-KADSSPKGSRGLGGLKSEFLKQSAARGLR-TQDLPAGSKDDSAAAPKTPWGI 795

Query: 508 QSLQERGLLRDQVFGCQLESLCQ--REGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLA 565
             +++      + FG +LE  CQ   E   VP  +  C   V+ RGL+  GIYRV GN A
Sbjct: 796 NIIKKNKKAAPRAFGVRLEE-CQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNA 854

Query: 566 VVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQP 625
           VV  L+  ++R                   G ++L    W D++V++  LK F R+LP+P
Sbjct: 855 VVSSLQEQLNRG-----------------PGDINLQDERWQDLNVISSLLKSFFRKLPEP 897

Query: 626 LVPPLLLPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRM 685
           L        F  A  + ++ + +  +++LI  +P   ++TL++L+ HL  +  HS+KN+M
Sbjct: 898 LFTDDKYNDFIEANRIEDARERMRTLRKLIRDLPGHYYETLKFLVGHLKTIADHSEKNKM 957

Query: 686 TPHNLGIVFGPTLFR-PEQETSDPAAH 711
            P NL +VFGPTL R  E   +D   H
Sbjct: 958 EPRNLALVFGPTLVRTSEDNMTDMVTH 984


>gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens]
          Length = 459

 Score =  120 bits (302), Expect = 3e-27
 Identities = 70/213 (32%), Positives = 113/213 (53%), Gaps = 18/213 (8%)

Query: 519 QVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRER 578
           +V+ C L +L +      P  + +CI  ++ RGL+ +G+YRVSG   +++ ++   DR  
Sbjct: 264 KVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDR-- 321

Query: 579 AVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAA 638
               DG            + D+    ++DI+++TGALKL+ R+LP PL+     P F  +
Sbjct: 322 ----DGE-----------KADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIES 366

Query: 639 LALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTL 698
             + + ++ L  + E +  +P  + +TLRYL+ HL RV  H  +N M   NLGIVFGPTL
Sbjct: 367 AKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTL 426

Query: 699 FR-PEQETSDPAAHALYPGQLVQLMLTNFTSLF 730
            R PE +         Y   +V+L++ N   LF
Sbjct: 427 MRSPELDAMAALNDIRYQRLVVELLIKNEDILF 459


>gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens]
          Length = 433

 Score =  120 bits (302), Expect = 3e-27
 Identities = 70/213 (32%), Positives = 113/213 (53%), Gaps = 18/213 (8%)

Query: 519 QVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRER 578
           +V+ C L +L +      P  + +CI  ++ RGL+ +G+YRVSG   +++ ++   DR  
Sbjct: 238 KVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDR-- 295

Query: 579 AVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAA 638
               DG            + D+    ++DI+++TGALKL+ R+LP PL+     P F  +
Sbjct: 296 ----DGE-----------KADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIES 340

Query: 639 LALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTL 698
             + + ++ L  + E +  +P  + +TLRYL+ HL RV  H  +N M   NLGIVFGPTL
Sbjct: 341 AKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTL 400

Query: 699 FR-PEQETSDPAAHALYPGQLVQLMLTNFTSLF 730
            R PE +         Y   +V+L++ N   LF
Sbjct: 401 MRSPELDAMAALNDIRYQRLVVELLIKNEDILF 433


>gi|4757980 beta chimerin isoform 2 [Homo sapiens]
          Length = 468

 Score =  119 bits (299), Expect = 8e-27
 Identities = 68/213 (31%), Positives = 116/213 (54%), Gaps = 18/213 (8%)

Query: 519 QVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRER 578
           +V+ C L +L +      P  + +CI  ++ RGL  +G+YRVSG    ++ ++   DR  
Sbjct: 273 KVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDR-- 330

Query: 579 AVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAA 638
               DG            + D+ +  + DI+++TGALKL+ R+LP P++       F  A
Sbjct: 331 ----DGE-----------KADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDA 375

Query: 639 LALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTL 698
             +S +++ L  + E++  +P  +++TLRYL+ HL +V  +   N M   NLGIVFGPTL
Sbjct: 376 AKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTL 435

Query: 699 FRPEQETSDPAAHAL-YPGQLVQLMLTNFTSLF 730
            RP ++++    H + Y   +VQ+++ N   LF
Sbjct: 436 MRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF 468


>gi|91106928 beta chimerin isoform 1 [Homo sapiens]
          Length = 332

 Score =  119 bits (299), Expect = 8e-27
 Identities = 68/213 (31%), Positives = 116/213 (54%), Gaps = 18/213 (8%)

Query: 519 QVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRER 578
           +V+ C L +L +      P  + +CI  ++ RGL  +G+YRVSG    ++ ++   DR  
Sbjct: 137 KVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDR-- 194

Query: 579 AVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAA 638
               DG            + D+ +  + DI+++TGALKL+ R+LP P++       F  A
Sbjct: 195 ----DGE-----------KADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDA 239

Query: 639 LALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTL 698
             +S +++ L  + E++  +P  +++TLRYL+ HL +V  +   N M   NLGIVFGPTL
Sbjct: 240 AKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTL 299

Query: 699 FRPEQETSDPAAHAL-YPGQLVQLMLTNFTSLF 730
            RP ++++    H + Y   +VQ+++ N   LF
Sbjct: 300 MRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF 332


>gi|229094128 active breakpoint cluster region-related  protein
           isoform c [Homo sapiens]
          Length = 813

 Score =  115 bits (288), Expect = 1e-25
 Identities = 69/187 (36%), Positives = 99/187 (52%), Gaps = 18/187 (9%)

Query: 520 VFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERA 579
           VFG ++  + +RE   VP  +R C+  V+KRG++  GIYR+SG    +Q L+ + D   A
Sbjct: 598 VFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFD---A 654

Query: 580 VTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAAL 639
              D   +  +                DI+ + G LKL+ RELP+PL+   L P F   +
Sbjct: 655 NNKDILLMLSDM---------------DINAIAGTLKLYFRELPEPLLTDRLYPAFMEGI 699

Query: 640 ALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLF 699
           ALS+     + +  L+ S+P PN  T  +LLEHL RV      N+M+ HNL  VFGPTL 
Sbjct: 700 ALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLL 759

Query: 700 RPEQETS 706
           RP +  S
Sbjct: 760 RPSEVES 766


>gi|38679957 active breakpoint cluster region-related  protein
           isoform a [Homo sapiens]
          Length = 859

 Score =  115 bits (288), Expect = 1e-25
 Identities = 69/187 (36%), Positives = 99/187 (52%), Gaps = 18/187 (9%)

Query: 520 VFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERA 579
           VFG ++  + +RE   VP  +R C+  V+KRG++  GIYR+SG    +Q L+ + D   A
Sbjct: 644 VFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFD---A 700

Query: 580 VTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAAL 639
              D   +  +                DI+ + G LKL+ RELP+PL+   L P F   +
Sbjct: 701 NNKDILLMLSDM---------------DINAIAGTLKLYFRELPEPLLTDRLYPAFMEGI 745

Query: 640 ALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLF 699
           ALS+     + +  L+ S+P PN  T  +LLEHL RV      N+M+ HNL  VFGPTL 
Sbjct: 746 ALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLL 805

Query: 700 RPEQETS 706
           RP +  S
Sbjct: 806 RPSEVES 812


>gi|38679954 active breakpoint cluster region-related  protein
           isoform b [Homo sapiens]
          Length = 822

 Score =  115 bits (288), Expect = 1e-25
 Identities = 69/187 (36%), Positives = 99/187 (52%), Gaps = 18/187 (9%)

Query: 520 VFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERA 579
           VFG ++  + +RE   VP  +R C+  V+KRG++  GIYR+SG    +Q L+ + D   A
Sbjct: 607 VFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFD---A 663

Query: 580 VTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAAL 639
              D   +  +                DI+ + G LKL+ RELP+PL+   L P F   +
Sbjct: 664 NNKDILLMLSDM---------------DINAIAGTLKLYFRELPEPLLTDRLYPAFMEGI 708

Query: 640 ALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLF 699
           ALS+     + +  L+ S+P PN  T  +LLEHL RV      N+M+ HNL  VFGPTL 
Sbjct: 709 ALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLL 768

Query: 700 RPEQETS 706
           RP +  S
Sbjct: 769 RPSEVES 775


>gi|218083800 Rho GTPase-activating protein isoform 1 [Homo sapiens]
          Length = 2087

 Score =  115 bits (288), Expect = 1e-25
 Identities = 72/225 (32%), Positives = 113/225 (50%), Gaps = 20/225 (8%)

Query: 480 SSIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSF 539
           +S+  P   +  ++   L+  +  RP  Q L++RG+L+++VFGC L       G  VP  
Sbjct: 329 NSVPKPVSKKHGKLITFLRTFMKSRPTKQKLKQRGILKERVFGCDLGEHLLNSGFEVPQV 388

Query: 540 LRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLD 599
           L+ C A +++ G+ VDGIYR+SG  + +Q+LR   D E                     D
Sbjct: 389 LQSCTAFIERYGI-VDGIYRLSGVASNIQRLRHEFDSEHVP------------------D 429

Query: 600 LDSTEW-DDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSM 658
           L    +  DIH V    KL+ RELP PL+   L   F  A++ +  E+ L +I ++I  +
Sbjct: 430 LTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVIQQL 489

Query: 659 PKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLFRPEQ 703
           P P++ TL +L+ HL  +  +     M   NL IV+ P L R +Q
Sbjct: 490 PPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQ 534


>gi|29469071 Rho GTPase-activating protein isoform 2 [Homo sapiens]
          Length = 1738

 Score =  111 bits (277), Expect = 3e-24
 Identities = 69/201 (34%), Positives = 103/201 (51%), Gaps = 20/201 (9%)

Query: 504 RPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGN 563
           RP  Q L++RG+L+++VFGC L       G  VP  L+ C A +++ G+ VDGIYR+SG 
Sbjct: 4   RPTKQKLKQRGILKERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGI-VDGIYRLSGV 62

Query: 564 LAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEW-DDIHVVTGALKLFLREL 622
            + +Q+LR   D E                     DL    +  DIH V    KL+ REL
Sbjct: 63  ASNIQRLRHEFDSEHVP------------------DLTKEPYVQDIHSVGSLCKLYFREL 104

Query: 623 PQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDK 682
           P PL+   L   F  A++ +  E+ L +I ++I  +P P++ TL +L+ HL  +  +   
Sbjct: 105 PNPLLTYQLYEKFSDAVSAATDEERLIKIHDVIQQLPPPHYRTLEFLMRHLSLLADYCSI 164

Query: 683 NRMTPHNLGIVFGPTLFRPEQ 703
             M   NL IV+ P L R +Q
Sbjct: 165 TNMHAKNLAIVWAPNLLRSKQ 185


>gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens]
          Length = 1271

 Score =  109 bits (273), Expect = 8e-24
 Identities = 80/260 (30%), Positives = 125/260 (48%), Gaps = 23/260 (8%)

Query: 459  EDEEEESELVSKPLLRLSSRRSSIRGPEGT--EQNRVRNKLK-RLIAKRPPLQSLQERGL 515
            ED E    L+ K  ++L  +    R  + T    N +  KL  +  ++   L+ +  R  
Sbjct: 989  EDGESTDRLMGKGQVQLDPQALQDRDWQRTVIAMNGIEVKLSVKFNSREFSLKRMPSRK- 1047

Query: 516  LRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVD 575
             +  VFG ++  + +RE   VP  +R C+  +++RG++  GIYRVSG    +Q L+   D
Sbjct: 1048 -QTGVFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFD 1106

Query: 576  RERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHF 635
                   D   +  E                D++ + G LKL+ RELP+PL      P+F
Sbjct: 1107 VNN---KDVSVMMSEM---------------DVNAIAGTLKLYFRELPEPLFTDEFYPNF 1148

Query: 636  RAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFG 695
               +ALS+     S +  L+ S+P+ N  T  +LL+HL RV      N+M+ HNL  VFG
Sbjct: 1149 AEGIALSDPVAKESCMLNLLLSLPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFG 1208

Query: 696  PTLFRPEQETSDPAAHALYP 715
            PTL RP ++ S   A+   P
Sbjct: 1209 PTLLRPSEKESKLPANPSQP 1228


>gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens]
          Length = 1227

 Score =  109 bits (272), Expect = 1e-23
 Identities = 67/196 (34%), Positives = 100/196 (51%), Gaps = 18/196 (9%)

Query: 520  VFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERA 579
            VFG ++  + +RE   VP  +R C+  +++RG++  GIYRVSG    +Q L+   D    
Sbjct: 1007 VFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNN- 1065

Query: 580  VTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAAL 639
               D   +  E                D++ + G LKL+ RELP+PL      P+F   +
Sbjct: 1066 --KDVSVMMSEM---------------DVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGI 1108

Query: 640  ALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLF 699
            ALS+     S +  L+ S+P+ N  T  +LL+HL RV      N+M+ HNL  VFGPTL 
Sbjct: 1109 ALSDPVAKESCMLNLLLSLPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTLL 1168

Query: 700  RPEQETSDPAAHALYP 715
            RP ++ S   A+   P
Sbjct: 1169 RPSEKESKLPANPSQP 1184


>gi|203097003 Rho GTPase activating protein 21 [Homo sapiens]
          Length = 1958

 Score =  107 bits (266), Expect = 5e-23
 Identities = 92/388 (23%), Positives = 168/388 (43%), Gaps = 61/388 (15%)

Query: 345  WGPSWVVLTGNSLVFYREP-PPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVL 403
            W   +VVL G+SL  Y++    T PS          E  + +    +      + R+NV 
Sbjct: 958  WKQMYVVLRGHSLYLYKDKREQTTPSE--------EEQPISVNACLIDISYSETKRKNVF 1009

Query: 404  HIRTIPGHEFLLQSDHETELRAWHRALRTVIERLDRENPLELRLSGSGPAELSAGEDEE- 462
             + T    E L Q++   ++ AW       I+ +   + L    +G    +L +   +E 
Sbjct: 1010 RLTT-SDCECLFQAEDRDDMLAW-------IKTIQESSNLNEEDTGVTNRDLISRRIKEY 1061

Query: 463  -----EESELVSKPLLRLSSRRSSIRG---PEGTEQNRVRNKLKRLIAKRPPLQSLQERG 514
                 +  +L   P   LS R++ +     P+    +  + + +R +  +      +++G
Sbjct: 1062 NNLMSKAEQLPKTPRQSLSIRQTLLGAKSEPKTQSPHSPKEESERKLLSKDDTSPPKDKG 1121

Query: 515  LLRDQV-----------------FGCQLESLCQREGDT-VPSFLRLCIAAVDKRGLDVDG 556
              R  +                 FG +L+       +  +P  + +C   V++RGL+  G
Sbjct: 1122 TWRKGIPSIMRKTFEKKPTATGTFGVRLDDCPPAHTNRYIPLIVDICCKLVEERGLEYTG 1181

Query: 557  IYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALK 616
            IYRV GN A +  ++  +++  A                  +D+   +W D++V++  LK
Sbjct: 1182 IYRVPGNNAAISSMQEELNKGMA-----------------DIDIQDDKWRDLNVISSLLK 1224

Query: 617  LFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRV 676
             F R+LP+PL        F  A    +    L  ++ LI  +P+ +++TL++L  HL  V
Sbjct: 1225 SFFRKLPEPLFTNDKYADFIEANRKEDPLDRLKTLKRLIHDLPEHHYETLKFLSAHLKTV 1284

Query: 677  IAHSDKNRMTPHNLGIVFGPTLFRPEQE 704
              +S+KN+M P NL IVFGPTL R  ++
Sbjct: 1285 AENSEKNKMEPRNLAIVFGPTLVRTSED 1312


>gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo
            sapiens]
          Length = 1499

 Score =  103 bits (258), Expect = 4e-22
 Identities = 74/227 (32%), Positives = 111/227 (48%), Gaps = 26/227 (11%)

Query: 486  EGTEQNRVRNKLKRLI--AKRP---PLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFL 540
            E  E  R RN L+ L    K+P   P  S+  +       FG  L ++   E   +P F+
Sbjct: 1208 ETDEDPRRRNILRSLRRNTKKPKPKPRPSIT-KATWESNYFGVPLTTVVTPE-KPIPIFI 1265

Query: 541  RLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDL 600
              CI  ++  GL  +GIYRVSGN + ++ L+   D                  Q+  LDL
Sbjct: 1266 ERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFD------------------QDHNLDL 1307

Query: 601  DSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPK 660
               ++  ++ V GA+K F  ELP PLVP  +      A  +++ EQ L  ++E++   PK
Sbjct: 1308 AEKDFT-VNTVAGAMKSFFSELPDPLVPYNMQIDLVEAHKINDREQKLHALKEVLKKFPK 1366

Query: 661  PNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLFRPEQETSD 707
             NH+  +Y++ HL +V  ++  N MT  NL I F PTL RP+  T D
Sbjct: 1367 ENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTLMRPDFSTMD 1413


>gi|208022687 GTPase regulator associated with the focal adhesion
           kinase pp125 isoform b [Homo sapiens]
          Length = 759

 Score =  103 bits (257), Expect = 6e-22
 Identities = 66/194 (34%), Positives = 100/194 (51%), Gaps = 17/194 (8%)

Query: 538 SFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKL-RFLVDRERAVTSDGRYVFPEQPGQEG 596
           S +R CI AV+ RG++  G+YR+ G  + VQKL   L+D + A               E 
Sbjct: 391 SIIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTA--------------SET 436

Query: 597 RLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIG 656
             D+   EW+ I  +T ALK +LR LP PL+       F  A  L   E  +S+I  L+ 
Sbjct: 437 ETDI-CAEWE-IKTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVH 494

Query: 657 SMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPG 716
            +P+ N   L+ L+ HL  V  +  +N MT  NLG+VFGPTL RP++ET        +  
Sbjct: 495 RLPEKNRQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQEETVAAIMDIKFQN 554

Query: 717 QLVQLMLTNFTSLF 730
            ++++++ N   +F
Sbjct: 555 IVIEILIENHEKIF 568


>gi|7662208 GTPase regulator associated with the focal adhesion
           kinase pp125 isoform a [Homo sapiens]
          Length = 814

 Score =  103 bits (257), Expect = 6e-22
 Identities = 66/194 (34%), Positives = 100/194 (51%), Gaps = 17/194 (8%)

Query: 538 SFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKL-RFLVDRERAVTSDGRYVFPEQPGQEG 596
           S +R CI AV+ RG++  G+YR+ G  + VQKL   L+D + A               E 
Sbjct: 391 SIIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTA--------------SET 436

Query: 597 RLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIG 656
             D+   EW+ I  +T ALK +LR LP PL+       F  A  L   E  +S+I  L+ 
Sbjct: 437 ETDI-CAEWE-IKTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVH 494

Query: 657 SMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPG 716
            +P+ N   L+ L+ HL  V  +  +N MT  NLG+VFGPTL RP++ET        +  
Sbjct: 495 RLPEKNRQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQEETVAAIMDIKFQN 554

Query: 717 QLVQLMLTNFTSLF 730
            ++++++ N   +F
Sbjct: 555 IVIEILIENHEKIF 568


>gi|71040096 Rho GTPase activating protein 30 isoform 2 [Homo
           sapiens]
          Length = 890

 Score =  103 bits (256), Expect = 7e-22
 Identities = 71/221 (32%), Positives = 109/221 (49%), Gaps = 21/221 (9%)

Query: 508 QSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVV 567
           Q  +++G  +++VFGC L+   Q  G  VP  L+ C   V++ G+ VDGIYR+SG  + +
Sbjct: 5   QKGKKKGSAKERVFGCDLQEHLQHSGQEVPQVLKSCAEFVEEYGV-VDGIYRLSGVSSNI 63

Query: 568 QKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEW-DDIHVVTGALKLFLRELPQPL 626
           QKLR   + ER                  + DL    +  DIH V+   K + RELP PL
Sbjct: 64  QKLRQEFESER------------------KPDLRRDVYLQDIHCVSSLCKAYFRELPDPL 105

Query: 627 VPPLLLPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMT 686
           +   L   F  A+ +    + L +I E++  +P PN+ TL +L+ HL  + + S +  M 
Sbjct: 106 LTYRLYDKFAEAVGVQLEPERLVKILEVLRELPVPNYRTLEFLMRHLVHMASFSAQTNMH 165

Query: 687 PHNLGIVFGPTLFRPEQ-ETSDPAAHALYPGQLVQLMLTNF 726
             NL IV+ P L R +  E S     A +    VQ ++  F
Sbjct: 166 ARNLAIVWAPNLLRSKDIEASGFNGTAAFMEVRVQSIVVEF 206


>gi|71040098 Rho GTPase activating protein 30 isoform 1 [Homo
           sapiens]
          Length = 1101

 Score =  103 bits (256), Expect = 7e-22
 Identities = 71/221 (32%), Positives = 109/221 (49%), Gaps = 21/221 (9%)

Query: 508 QSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVV 567
           Q  +++G  +++VFGC L+   Q  G  VP  L+ C   V++ G+ VDGIYR+SG  + +
Sbjct: 5   QKGKKKGSAKERVFGCDLQEHLQHSGQEVPQVLKSCAEFVEEYGV-VDGIYRLSGVSSNI 63

Query: 568 QKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEW-DDIHVVTGALKLFLRELPQPL 626
           QKLR   + ER                  + DL    +  DIH V+   K + RELP PL
Sbjct: 64  QKLRQEFESER------------------KPDLRRDVYLQDIHCVSSLCKAYFRELPDPL 105

Query: 627 VPPLLLPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMT 686
           +   L   F  A+ +    + L +I E++  +P PN+ TL +L+ HL  + + S +  M 
Sbjct: 106 LTYRLYDKFAEAVGVQLEPERLVKILEVLRELPVPNYRTLEFLMRHLVHMASFSAQTNMH 165

Query: 687 PHNLGIVFGPTLFRPEQ-ETSDPAAHALYPGQLVQLMLTNF 726
             NL IV+ P L R +  E S     A +    VQ ++  F
Sbjct: 166 ARNLAIVWAPNLLRSKDIEASGFNGTAAFMEVRVQSIVVEF 206


>gi|4505507 oligophrenin 1 [Homo sapiens]
          Length = 802

 Score =  102 bits (255), Expect = 1e-21
 Identities = 56/192 (29%), Positives = 100/192 (52%), Gaps = 16/192 (8%)

Query: 539 FLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRL 598
           F+R CI  ++ +G+  +G+YR  G+   VQKL               +  P+ PG    +
Sbjct: 389 FVRKCINIIETKGIKTEGLYRTVGSNIQVQKLL------------NAFFDPKCPGD---V 433

Query: 599 DLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSM 658
           D  +++WD I  +T +LK +LR L +P++   L     +A      +  L  I  L+  +
Sbjct: 434 DFHNSDWD-IKTITSSLKFYLRNLSEPVMTYRLHKELVSAAKSDNLDYRLGAIHSLVYKL 492

Query: 659 PKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPGQL 718
           P+ N + L  L+ HL  V  HS +N MTP N+G++FGPTL R +++T     +  +   +
Sbjct: 493 PEKNREMLELLIRHLVNVCEHSKENLMTPSNMGVIFGPTLMRAQEDTVAAMMNIKFQNIV 552

Query: 719 VQLMLTNFTSLF 730
           V++++ +F  ++
Sbjct: 553 VEILIEHFGKIY 564


>gi|156071465 Rho GTPase activating protein 4 [Homo sapiens]
          Length = 946

 Score =  102 bits (253), Expect = 2e-21
 Identities = 91/316 (28%), Positives = 127/316 (40%), Gaps = 62/316 (19%)

Query: 445 LRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRNKLKRLIAKR 504
           L+ + S P    AG    ++ E  +  L +L    S             R+ L +L AK 
Sbjct: 414 LKSTSSDPGSRQAGRRRGQQQETETFYLTKLQEYLSG------------RSILAKLQAKH 461

Query: 505 PPLQSLQERGLLRDQ---------------------------VFGCQLESLCQREGDTVP 537
             LQ   +RG   +Q                           +FG  +E   Q  G  VP
Sbjct: 462 EKLQEALQRGDKEEQEVSWTQYTQRKFQKSRQPRPSSQYNQRLFGGDMEKFIQSSGQPVP 521

Query: 538 SFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGR 597
             +  CI  ++  GL  +GI+RVSG    V ++R   +R             E P  EG 
Sbjct: 522 LVVESCIRFINLNGLQHEGIFRVSGAQLRVSEIRDAFERG------------EDPLVEGC 569

Query: 598 L--DLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELI 655
              DLDS        V G LKL+ R L  PL PP L     A+  L  + + +  +  L+
Sbjct: 570 TAHDLDS--------VAGVLKLYFRSLEPPLFPPDLFGELLASSELEATAERVEHVSRLL 621

Query: 656 GSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYP 715
             +P P    LRYL   L  +  +SD+N M P+NL + FGPTL  P     DP A     
Sbjct: 622 WRLPAPVLVVLRYLFTFLNHLAQYSDENMMDPYNLAVCFGPTLL-PVPAGQDPVALQGRV 680

Query: 716 GQLVQLMLTNFTSLFP 731
            QLVQ ++     +FP
Sbjct: 681 NQLVQTLIVQPDRVFP 696



 Score = 35.0 bits (79), Expect = 0.25
 Identities = 14/34 (41%), Positives = 19/34 (55%)

Query: 29  ALYAFTYTGADGQQVSLAEGDRFLLLRKTNSDWW 62
           A+  F YTG   Q++S   GD   L  + +SDWW
Sbjct: 751 AVACFAYTGRTAQELSFRRGDVLRLHERASSDWW 784


>gi|50843948 Rho GTPase activating protein 10 [Homo sapiens]
          Length = 786

 Score =  101 bits (252), Expect = 2e-21
 Identities = 62/194 (31%), Positives = 102/194 (52%), Gaps = 17/194 (8%)

Query: 538 SFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKL-RFLVDRERAVTSDGRYVFPEQPGQEG 596
           + +R CI+AV+ RG++  G+YRV G  + VQ+L   L+D +                   
Sbjct: 397 TIIRKCISAVETRGINDQGLYRVVGVSSKVQRLLSMLMDVKTC----------------N 440

Query: 597 RLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIG 656
            +DL+++   ++  +T ALK +LR LP+PL+   L   F         E  ++ I  L+ 
Sbjct: 441 EVDLENSADWEVKTITSALKQYLRSLPEPLMTYELHGDFIVPAKSGSPESRVNAIHFLVH 500

Query: 657 SMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPG 716
            +P+ N + L  L++HL  V  HS +N MT  NLG+VFGPTL RP++ET        +  
Sbjct: 501 KLPEKNKEMLDILVKHLTNVSNHSKQNLMTVANLGVVFGPTLMRPQEETVAALMDLKFQN 560

Query: 717 QLVQLMLTNFTSLF 730
            +V++++ N   +F
Sbjct: 561 IVVEILIENHEKIF 574


>gi|221307575 Rho-type GTPase-activating protein FLJ32810 [Homo
           sapiens]
          Length = 874

 Score =  101 bits (251), Expect = 3e-21
 Identities = 59/193 (30%), Positives = 101/193 (52%), Gaps = 16/193 (8%)

Query: 538 SFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGR 597
           +F+R CI AV+ RG+ + G+YR+ G  + VQKL                  P+ P     
Sbjct: 396 NFVRKCIQAVETRGITILGLYRIGGVNSKVQKLM------------NTTFSPKSPPD--- 440

Query: 598 LDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGS 657
           +D+D   WD+   +T  LK +LR L +PL+   L   F  A+   +    +  +  L+  
Sbjct: 441 IDIDIELWDN-KTITSGLKNYLRCLAEPLMTYKLHKDFIIAVKSDDQNYRVEAVHALVHK 499

Query: 658 MPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPGQ 717
           +P+ N + L  L++HL +V  HS +N MT  NLG++FGPTL R ++ET     +  +   
Sbjct: 500 LPEKNREMLDILIKHLVKVSLHSQQNLMTVSNLGVIFGPTLMRAQEETVAAMMNIKFQNI 559

Query: 718 LVQLMLTNFTSLF 730
           +V++++ ++  +F
Sbjct: 560 VVEILIEHYEKIF 572


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.134    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,113,234
Number of Sequences: 37866
Number of extensions: 1976901
Number of successful extensions: 9359
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 141
Number of HSP's successfully gapped in prelim test: 294
Number of HSP's that attempted gapping in prelim test: 8606
Number of HSP's gapped (non-prelim): 931
length of query: 731
length of database: 18,247,518
effective HSP length: 110
effective length of query: 621
effective length of database: 14,082,258
effective search space: 8745082218
effective search space used: 8745082218
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.