Guide to the Human Genome
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Search of human proteins with 32699048

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|32699048 family with sequence similarity 70, member B [Homo
sapiens]
         (326 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|32699048 family with sequence similarity 70, member B [Homo s...   672   0.0  
gi|157388933 hypothetical protein LOC55026 isoform 2 [Homo sapiens]   318   3e-87
gi|157388931 hypothetical protein LOC55026 isoform 1 [Homo sapiens]   313   1e-85
gi|239757890 PREDICTED: similar to family with sequence similari...   307   7e-84
gi|157388935 hypothetical protein LOC55026 isoform 3 [Homo sapiens]   172   4e-43
gi|239750593 PREDICTED: hypothetical protein XP_002347442 [Homo ...   128   8e-30
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap...    47   2e-05
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    43   3e-04
gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo s...    42   6e-04
gi|209529736 mitogen-activated protein kinase 7 isoform 1 [Homo ...    42   6e-04
gi|209529734 mitogen-activated protein kinase 7 isoform 1 [Homo ...    42   6e-04
gi|20986499 mitogen-activated protein kinase 7 isoform 2 [Homo s...    42   6e-04
gi|51173727 Sma- and Mad-related protein 1 [Homo sapiens]              41   0.002
gi|5174509 Sma- and Mad-related protein 1 [Homo sapiens]               41   0.002
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    40   0.002
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    40   0.004
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    40   0.004
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]                     39   0.005
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]                     39   0.005
gi|47778931 SMAD, mothers against DPP homolog 5 [Homo sapiens]         39   0.005
gi|47778929 SMAD, mothers against DPP homolog 5 [Homo sapiens]         39   0.005
gi|47778925 SMAD, mothers against DPP homolog 5 [Homo sapiens]         39   0.005
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [...    39   0.005
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo...    39   0.005
gi|24430132 WW domain binding protein 2 [Homo sapiens]                 39   0.006
gi|157168329 formin 1 [Homo sapiens]                                   39   0.008
gi|9945318 MAX binding protein [Homo sapiens]                          39   0.008
gi|22547176 oxysterol binding protein-like 9 isoform f [Homo sap...    38   0.011
gi|22547173 oxysterol binding protein-like 9 isoform d [Homo sap...    38   0.011
gi|22547171 oxysterol binding protein-like 9 isoform c [Homo sap...    38   0.011

>gi|32699048 family with sequence similarity 70, member B [Homo
           sapiens]
          Length = 326

 Score =  672 bits (1733), Expect = 0.0
 Identities = 326/326 (100%), Positives = 326/326 (100%)

Query: 1   MQPPVPGPLGLLDPAEGLSRRKKTSLWFVGSLLLVSVLIVTVGLAATTRTENVTVGGYYP 60
           MQPPVPGPLGLLDPAEGLSRRKKTSLWFVGSLLLVSVLIVTVGLAATTRTENVTVGGYYP
Sbjct: 1   MQPPVPGPLGLLDPAEGLSRRKKTSLWFVGSLLLVSVLIVTVGLAATTRTENVTVGGYYP 60

Query: 61  GIILGFGSFLGIIGINLVENRRQMLVAAIVFISFGVVAAFCCAIVDGVFAAQHIEPRPLT 120
           GIILGFGSFLGIIGINLVENRRQMLVAAIVFISFGVVAAFCCAIVDGVFAAQHIEPRPLT
Sbjct: 61  GIILGFGSFLGIIGINLVENRRQMLVAAIVFISFGVVAAFCCAIVDGVFAAQHIEPRPLT 120

Query: 121 TGRCQFYSSGVGYLYDVYQTEVTCHSLDGKCQLKVRSNTCYCCDLYACGSAEPSPAYYEF 180
           TGRCQFYSSGVGYLYDVYQTEVTCHSLDGKCQLKVRSNTCYCCDLYACGSAEPSPAYYEF
Sbjct: 121 TGRCQFYSSGVGYLYDVYQTEVTCHSLDGKCQLKVRSNTCYCCDLYACGSAEPSPAYYEF 180

Query: 181 IGVSGCQDVLHLYRLLWASAVLNVLGLFLGIITAAVLGAFKDMVPLSQLAYGPAVPPQTL 240
           IGVSGCQDVLHLYRLLWASAVLNVLGLFLGIITAAVLGAFKDMVPLSQLAYGPAVPPQTL
Sbjct: 181 IGVSGCQDVLHLYRLLWASAVLNVLGLFLGIITAAVLGAFKDMVPLSQLAYGPAVPPQTL 240

Query: 241 YNPAQQILAYAGFRLTPEPVPTCSSYPLPLQPCSRFPVAPSSALASSEDLQPPSPSSSGS 300
           YNPAQQILAYAGFRLTPEPVPTCSSYPLPLQPCSRFPVAPSSALASSEDLQPPSPSSSGS
Sbjct: 241 YNPAQQILAYAGFRLTPEPVPTCSSYPLPLQPCSRFPVAPSSALASSEDLQPPSPSSSGS 300

Query: 301 GLPGQAPPCYAPTYFPPGEKPPPYAP 326
           GLPGQAPPCYAPTYFPPGEKPPPYAP
Sbjct: 301 GLPGQAPPCYAPTYFPPGEKPPPYAP 326


>gi|157388933 hypothetical protein LOC55026 isoform 2 [Homo sapiens]
          Length = 325

 Score =  318 bits (816), Expect = 3e-87
 Identities = 172/323 (53%), Positives = 217/323 (67%), Gaps = 15/323 (4%)

Query: 9   LGLLDPAEGLSRRKKTSLWFVGSLLLVSVLIVTVGLAATTRTENVTVGGYYPGIILGFGS 68
           + L D     +RRK+ S++   +LL+VSVLI+TVGLAATTRT+NVTVGGYYPG+ILGFGS
Sbjct: 13  MSLPDSMGAFNRRKRNSIYVTVTLLIVSVLILTVGLAATTRTQNVTVGGYYPGVILGFGS 72

Query: 69  FLGIIGINLVENRRQMLVAAIVFISFGVVAAFCCAIVDGVFAAQHIEPRPLTTGRCQFYS 128
           FLGIIG NL+EN+RQMLVA+IVFISFGV+AAFCCAIVDGVFAA+HI+ +PL   RC +  
Sbjct: 73  FLGIIGSNLIENKRQMLVASIVFISFGVIAAFCCAIVDGVFAARHIDLKPLYANRCHY-- 130

Query: 129 SGVGYLYDVYQTEVTCHSLDGK-CQLKVRSNTCYCCDLYACGS-AEPSPAYYEFIGVSGC 186
             V         EV C  L  + C  ++R NTC+CCDLY CG+  E +  YYE+I VS C
Sbjct: 131 --VPKTSQKEAEEVNCPHLSREFCTPRIRGNTCFCCDLYNCGNRVEITGGYYEYIDVSSC 188

Query: 187 QDVLHLYRLLWASAVLNVLGLFLGIITAAVLGAFKDMVPLSQLAYGPAVP---PQTLYNP 243
           QD++HLY LLW++ +LN++GLFLGIITAAVLG FKDM P +  A   +V    P   Y  
Sbjct: 189 QDIIHLYHLLWSATILNIVGLFLGIITAAVLGGFKDMNP-TLPALNCSVENTHPTVSYYA 247

Query: 244 AQQILAYAGFRLTPEPVPTCSSYPLPLQPCSRFPVAPSSALASSEDLQPPSPSSSGSGLP 303
             Q+ +Y  +  +P  +P  S+Y    Q    FP +P S L+       PSPS   S   
Sbjct: 248 HPQVASYNTYYHSPPHLPPYSAY--DFQHSGVFPSSPPSGLSDEPQSASPSPSYMWS--- 302

Query: 304 GQAPPCYAPTYFPPGEKPPPYAP 326
             APP Y+P Y+PP EKPPPY+P
Sbjct: 303 SSAPPRYSPPYYPPFEKPPPYSP 325


>gi|157388931 hypothetical protein LOC55026 isoform 1 [Homo sapiens]
          Length = 349

 Score =  313 bits (802), Expect = 1e-85
 Identities = 173/343 (50%), Positives = 221/343 (64%), Gaps = 31/343 (9%)

Query: 9   LGLLDPAEGLSRRKKTSLWFVGSLLLVSVLIVTVGLAATTRTENVTVGGYYPGIILGFGS 68
           + L D     +RRK+ S++   +LL+VSVLI+TVGLAATTRT+NVTVGGYYPG+ILGFGS
Sbjct: 13  MSLPDSMGAFNRRKRNSIYVTVTLLIVSVLILTVGLAATTRTQNVTVGGYYPGVILGFGS 72

Query: 69  FLGIIGINLVENRRQMLVAAIVFISFGVVAAFCCAIVDGVFAAQHIEPRPLTTGRCQFY- 127
           FLGIIG NL+EN+RQMLVA+IVFISFGV+AAFCCAIVDGVFAA+HI+ +PL   RC +  
Sbjct: 73  FLGIIGSNLIENKRQMLVASIVFISFGVIAAFCCAIVDGVFAARHIDLKPLYANRCHYVP 132

Query: 128 -----------------SSGVGYLYDVYQT--EVTCHSLDGK-CQLKVRSNTCYCCDLYA 167
                            S     + ++ Q   EV C  L  + C  ++R NTC+CCDLY 
Sbjct: 133 KTSQKEAEEVISSSTKNSPSTRVMRNLTQAAREVNCPHLSREFCTPRIRGNTCFCCDLYN 192

Query: 168 CGS-AEPSPAYYEFIGVSGCQDVLHLYRLLWASAVLNVLGLFLGIITAAVLGAFKDMVPL 226
           CG+  E +  YYE+I VS CQD++HLY LLW++ +LN++GLFLGIITAAVLG FKDM P 
Sbjct: 193 CGNRVEITGGYYEYIDVSSCQDIIHLYHLLWSATILNIVGLFLGIITAAVLGGFKDMNP- 251

Query: 227 SQLAYGPAVP---PQTLYNPAQQILAYAGFRLTPEPVPTCSSYPLPLQPCSRFPVAPSSA 283
           +  A   +V    P   Y    Q+ +Y  +  +P  +P  S+Y    Q    FP +P S 
Sbjct: 252 TLPALNCSVENTHPTVSYYAHPQVASYNTYYHSPPHLPPYSAY--DFQHSGVFPSSPPSG 309

Query: 284 LASSEDLQPPSPSSSGSGLPGQAPPCYAPTYFPPGEKPPPYAP 326
           L+       PSPS   S     APP Y+P Y+PP EKPPPY+P
Sbjct: 310 LSDEPQSASPSPSYMWS---SSAPPRYSPPYYPPFEKPPPYSP 349


>gi|239757890 PREDICTED: similar to family with sequence similarity
           70, member A [Homo sapiens]
          Length = 377

 Score =  307 bits (787), Expect = 7e-84
 Identities = 168/318 (52%), Positives = 212/318 (66%), Gaps = 15/318 (4%)

Query: 9   LGLLDPAEGLSRRKKTSLWFVGSLLLVSVLIVTVGLAATTRTENVTVGGYYPGIILGFGS 68
           + L D     +RRK+ S++   +LL+VSVLI+TVGLAATTRT+NVTVGGYYPG+ILGFGS
Sbjct: 13  MSLPDSMGAFNRRKRNSIYVTVTLLIVSVLILTVGLAATTRTQNVTVGGYYPGVILGFGS 72

Query: 69  FLGIIGINLVENRRQMLVAAIVFISFGVVAAFCCAIVDGVFAAQHIEPRPLTTGRCQFYS 128
           FLGIIG NL+EN+RQMLVA+IVFISFGV+AAFCCAIVDGVFAA+HI+ +PL   RC +  
Sbjct: 73  FLGIIGSNLIENKRQMLVASIVFISFGVIAAFCCAIVDGVFAARHIDLKPLYANRCHY-- 130

Query: 129 SGVGYLYDVYQTEVTCHSLDGK-CQLKVRSNTCYCCDLYACGS-AEPSPAYYEFIGVSGC 186
             V         EV C  L  + C  ++R NTC+CCDLY CG+  E +  YYE+I VS C
Sbjct: 131 --VPKTSQKEAEEVNCPHLSREFCTPRIRGNTCFCCDLYNCGNRVEITGGYYEYIDVSSC 188

Query: 187 QDVLHLYRLLWASAVLNVLGLFLGIITAAVLGAFKDMVPLSQLAYGPAVP---PQTLYNP 243
           QD++HLY LLW++ +LN++GLFLGIITAAVLG FKDM P +  A   +V    P   Y  
Sbjct: 189 QDIIHLYHLLWSATILNIVGLFLGIITAAVLGGFKDMNP-TLPALNCSVENTHPTVSYYA 247

Query: 244 AQQILAYAGFRLTPEPVPTCSSYPLPLQPCSRFPVAPSSALASSEDLQPPSPSSSGSGLP 303
             Q+ +Y  +  +P  +P  S+Y    Q    FP +P S L+       PSPS   S   
Sbjct: 248 HPQVASYNTYYHSPPHLPPYSAY--DFQHSGVFPSSPPSGLSDEPQSASPSPSYMWS--- 302

Query: 304 GQAPPCYAPTYFPPGEKP 321
             APP Y+P Y+PP EKP
Sbjct: 303 SSAPPRYSPPYYPPFEKP 320


>gi|157388935 hypothetical protein LOC55026 isoform 3 [Homo sapiens]
          Length = 241

 Score =  172 bits (436), Expect = 4e-43
 Identities = 83/118 (70%), Positives = 101/118 (85%)

Query: 9   LGLLDPAEGLSRRKKTSLWFVGSLLLVSVLIVTVGLAATTRTENVTVGGYYPGIILGFGS 68
           + L D     +RRK+ S++   +LL+VSVLI+TVGLAATTRT+NVTVGGYYPG+ILGFGS
Sbjct: 13  MSLPDSMGAFNRRKRNSIYVTVTLLIVSVLILTVGLAATTRTQNVTVGGYYPGVILGFGS 72

Query: 69  FLGIIGINLVENRRQMLVAAIVFISFGVVAAFCCAIVDGVFAAQHIEPRPLTTGRCQF 126
           FLGIIG NL+EN+RQMLVA+IVFISFGV+AAFCCAIVDGVFAA+HI+ +PL   RC +
Sbjct: 73  FLGIIGSNLIENKRQMLVASIVFISFGVIAAFCCAIVDGVFAARHIDLKPLYANRCHY 130



 Score = 65.1 bits (157), Expect = 8e-11
 Identities = 51/174 (29%), Positives = 72/174 (41%), Gaps = 32/174 (18%)

Query: 180 FIGVSGCQDVLHLYRLLWASAVLNVLGLFLGIITAAVLGAFK----DMVPL--------- 226
           F+G+ G   + +  ++L AS V    G+      A V G F     D+ PL         
Sbjct: 73  FLGIIGSNLIENKRQMLVASIVFISFGVIAAFCCAIVDGVFAARHIDLKPLYANRCHYVP 132

Query: 227 ----SQLAYGPAVP----------PQTLYNPAQQILAYAGFRLTPEPVPTCSSYPLPLQP 272
                +    P +P          P   Y    Q+ +Y  +  +P  +P  S+Y    Q 
Sbjct: 133 KTSQKEAEENPTLPALNCSVENTHPTVSYYAHPQVASYNTYYHSPPHLPPYSAYDF--QH 190

Query: 273 CSRFPVAPSSALASSEDLQPPSPSSSGSGLPGQAPPCYAPTYFPPGEKPPPYAP 326
              FP +P S L+       PSPS   S     APP Y+P Y+PP EKPPPY+P
Sbjct: 191 SGVFPSSPPSGLSDEPQSASPSPSYMWSS---SAPPRYSPPYYPPFEKPPPYSP 241


>gi|239750593 PREDICTED: hypothetical protein XP_002347442 [Homo
          sapiens]
          Length = 135

 Score =  128 bits (321), Expect = 8e-30
 Identities = 63/64 (98%), Positives = 64/64 (100%)

Query: 1  MQPPVPGPLGLLDPAEGLSRRKKTSLWFVGSLLLVSVLIVTVGLAATTRTENVTVGGYYP 60
          MQPPVPGPLGLLDPAEGLSRRKKTSLWFVGSLLLVSVLIVTVGLAATTRTENVTVGGYYP
Sbjct: 1  MQPPVPGPLGLLDPAEGLSRRKKTSLWFVGSLLLVSVLIVTVGLAATTRTENVTVGGYYP 60

Query: 61 GIIL 64
          GII+
Sbjct: 61 GIIV 64


>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
           sapiens]
          Length = 505

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 33/95 (34%), Positives = 38/95 (40%)

Query: 232 GPAVPPQTLYNPAQQILAYAGFRLTPEPVPTCSSYPLPLQPCSRFPVAPSSALASSEDLQ 291
           GP  PP           + A     P P P+  S  +P  P +R    P  AL SS    
Sbjct: 298 GPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSG 357

Query: 292 PPSPSSSGSGLPGQAPPCYAPTYFPPGEKPPPYAP 326
           PP P  S  G+   APP   P   PPG  PPP  P
Sbjct: 358 PPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPPGLP 392



 Score = 28.5 bits (62), Expect = 8.5
 Identities = 21/70 (30%), Positives = 23/70 (32%), Gaps = 4/70 (5%)

Query: 254 RLTPEPVPTCSSYPLPLQPCSRFPVAPSSALASSEDLQPPSPSSSGSGLPGQAPPCYAPT 313
           R  P P P     P P  P       P    A      PP PS + +  P   PP     
Sbjct: 274 RQAPPPPPPSRGGPPPPPPPPHNS-GPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSV 332

Query: 314 YFPPGEKPPP 323
             PP   PPP
Sbjct: 333 AVPP---PPP 339


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 38/127 (29%), Positives = 47/127 (37%), Gaps = 28/127 (22%)

Query: 225  PLSQLAYGPAVPPQTLYNPAQQILAYAGFRLTPEPVP----TCSSYP---LPLQPCSRFP 277
            P   LA  P   P  ++ P      YA   LTP P P    +C + P   LP  P SR P
Sbjct: 2354 PAQALAPSPPSHPD-IFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVP 2412

Query: 278  VAPSSALASSEDLQP-------------------PSPSSSGSGLPGQAPPCYAPTYFPPG 318
             +P S  +S   L P                   P P S     P    P +AP + PP 
Sbjct: 2413 ASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDP-FAPLHKPPR 2471

Query: 319  EKPPPYA 325
             +PP  A
Sbjct: 2472 PQPPEVA 2478



 Score = 33.1 bits (74), Expect = 0.34
 Identities = 33/106 (31%), Positives = 42/106 (39%), Gaps = 9/106 (8%)

Query: 225 PLSQLAYGPAVPPQTLYNPAQQILAYAGFRLTPEPVPTCSSYPLPLQPCSRFPVA-PSSA 283
           P S L   P  PP+   +P    L      L+P P  +  S P    P S  P   P+S 
Sbjct: 511 PFSPLEESPLSPPEE--SPPSPALETP---LSPPPEASPLSPPFEESPLSPPPEELPTSP 565

Query: 284 LASSEDLQPPSPSSSGSGLPGQAP---PCYAPTYFPPGEKPPPYAP 326
              +  L PP   S  S  P ++P   P  A   FPP E+ P   P
Sbjct: 566 PPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPP 611



 Score = 31.6 bits (70), Expect = 1.0
 Identities = 25/71 (35%), Positives = 31/71 (43%), Gaps = 7/71 (9%)

Query: 257  PEPVPTCSSYPLPLQPCSRFPVAPSSALASSEDLQPP-SPSSSGSGLPGQAPPCYAPTYF 315
            PEPVP     P+ L P    PV P+S +   E L P  SP    S +P  +PP       
Sbjct: 993  PEPVP-----PMILPPSPGSPVGPASPIL-MEPLPPQCSPLLQHSLVPQNSPPSQCSPPA 1046

Query: 316  PPGEKPPPYAP 326
             P   P P +P
Sbjct: 1047 LPLSVPSPLSP 1057



 Score = 31.2 bits (69), Expect = 1.3
 Identities = 25/71 (35%), Positives = 32/71 (45%), Gaps = 7/71 (9%)

Query: 257 PEPVPTCSSYPLPLQPCSRFPVAPSSALASSEDLQPP-SPSSSGSGLPGQAPPCYAPTYF 315
           PE +P    +P P +P S  P+    AL  SE  +PP SP      L     P  +P   
Sbjct: 877 PEELPL---FPPPGEP-SLSPLLGEPAL--SEPGEPPLSPLPEELPLSPSGEPSLSPQLM 930

Query: 316 PPGEKPPPYAP 326
           PP   PPP +P
Sbjct: 931 PPDPLPPPLSP 941


>gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo
           sapiens]
          Length = 816

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 33/96 (34%), Positives = 40/96 (41%), Gaps = 16/96 (16%)

Query: 236 PPQTLYNPAQQILAYAGFRLTPEPVPTC---SSYPLPLQPCSRFPV------APSSALAS 286
           PP  +  P       AG    P P P C      P P  P    PV      A S++L +
Sbjct: 606 PPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLA 665

Query: 287 SEDLQPPSPSSSGSGLPGQAPPCYAPTYFPPGEKPP 322
           ++ L PP       GLPG + P   P YFPPG  PP
Sbjct: 666 AQSLVPP------PGLPGSSTPGVLP-YFPPGLPPP 694



 Score = 35.0 bits (79), Expect = 0.091
 Identities = 23/70 (32%), Positives = 28/70 (40%), Gaps = 11/70 (15%)

Query: 257 PEPVPTCSSYPLPLQPCSRFPVAPSSALASSEDLQPPSPSSSGSGLPGQAPPCYAPTYFP 316
           P P P  +  P P+QP S     P   +A     QP S  S+   +P  A P       P
Sbjct: 587 PAPAPAPTPTPTPVQPTS----PPPGPVAQPTGPQPQSAGSTSGPVPQPACP-------P 635

Query: 317 PGEKPPPYAP 326
           PG  P P  P
Sbjct: 636 PGPAPHPTGP 645


>gi|209529736 mitogen-activated protein kinase 7 isoform 1 [Homo
           sapiens]
          Length = 816

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 33/96 (34%), Positives = 40/96 (41%), Gaps = 16/96 (16%)

Query: 236 PPQTLYNPAQQILAYAGFRLTPEPVPTC---SSYPLPLQPCSRFPV------APSSALAS 286
           PP  +  P       AG    P P P C      P P  P    PV      A S++L +
Sbjct: 606 PPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLA 665

Query: 287 SEDLQPPSPSSSGSGLPGQAPPCYAPTYFPPGEKPP 322
           ++ L PP       GLPG + P   P YFPPG  PP
Sbjct: 666 AQSLVPP------PGLPGSSTPGVLP-YFPPGLPPP 694



 Score = 35.0 bits (79), Expect = 0.091
 Identities = 23/70 (32%), Positives = 28/70 (40%), Gaps = 11/70 (15%)

Query: 257 PEPVPTCSSYPLPLQPCSRFPVAPSSALASSEDLQPPSPSSSGSGLPGQAPPCYAPTYFP 316
           P P P  +  P P+QP S     P   +A     QP S  S+   +P  A P       P
Sbjct: 587 PAPAPAPTPTPTPVQPTS----PPPGPVAQPTGPQPQSAGSTSGPVPQPACP-------P 635

Query: 317 PGEKPPPYAP 326
           PG  P P  P
Sbjct: 636 PGPAPHPTGP 645


>gi|209529734 mitogen-activated protein kinase 7 isoform 1 [Homo
           sapiens]
          Length = 816

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 33/96 (34%), Positives = 40/96 (41%), Gaps = 16/96 (16%)

Query: 236 PPQTLYNPAQQILAYAGFRLTPEPVPTC---SSYPLPLQPCSRFPV------APSSALAS 286
           PP  +  P       AG    P P P C      P P  P    PV      A S++L +
Sbjct: 606 PPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLA 665

Query: 287 SEDLQPPSPSSSGSGLPGQAPPCYAPTYFPPGEKPP 322
           ++ L PP       GLPG + P   P YFPPG  PP
Sbjct: 666 AQSLVPP------PGLPGSSTPGVLP-YFPPGLPPP 694



 Score = 35.0 bits (79), Expect = 0.091
 Identities = 23/70 (32%), Positives = 28/70 (40%), Gaps = 11/70 (15%)

Query: 257 PEPVPTCSSYPLPLQPCSRFPVAPSSALASSEDLQPPSPSSSGSGLPGQAPPCYAPTYFP 316
           P P P  +  P P+QP S     P   +A     QP S  S+   +P  A P       P
Sbjct: 587 PAPAPAPTPTPTPVQPTS----PPPGPVAQPTGPQPQSAGSTSGPVPQPACP-------P 635

Query: 317 PGEKPPPYAP 326
           PG  P P  P
Sbjct: 636 PGPAPHPTGP 645


>gi|20986499 mitogen-activated protein kinase 7 isoform 2 [Homo
           sapiens]
          Length = 677

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 33/96 (34%), Positives = 40/96 (41%), Gaps = 16/96 (16%)

Query: 236 PPQTLYNPAQQILAYAGFRLTPEPVPTC---SSYPLPLQPCSRFPV------APSSALAS 286
           PP  +  P       AG    P P P C      P P  P    PV      A S++L +
Sbjct: 467 PPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLA 526

Query: 287 SEDLQPPSPSSSGSGLPGQAPPCYAPTYFPPGEKPP 322
           ++ L PP       GLPG + P   P YFPPG  PP
Sbjct: 527 AQSLVPP------PGLPGSSTPGVLP-YFPPGLPPP 555



 Score = 35.0 bits (79), Expect = 0.091
 Identities = 23/70 (32%), Positives = 28/70 (40%), Gaps = 11/70 (15%)

Query: 257 PEPVPTCSSYPLPLQPCSRFPVAPSSALASSEDLQPPSPSSSGSGLPGQAPPCYAPTYFP 316
           P P P  +  P P+QP S     P   +A     QP S  S+   +P  A P       P
Sbjct: 448 PAPAPAPTPTPTPVQPTS----PPPGPVAQPTGPQPQSAGSTSGPVPQPACP-------P 496

Query: 317 PGEKPPPYAP 326
           PG  P P  P
Sbjct: 497 PGPAPHPTGP 506


>gi|51173727 Sma- and Mad-related protein 1 [Homo sapiens]
          Length = 465

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 32/100 (32%), Positives = 41/100 (41%), Gaps = 19/100 (19%)

Query: 235 VPPQTLYNPAQQILAYAGFR-------------LTPEPVPTCSSYPLPLQPCSRFPVAPS 281
           VP  + YNP   +LA   FR               P+     +S+P P  P S +P +P 
Sbjct: 140 VPRHSEYNPQHSLLAQ--FRNLGQNEPHMPLNATFPDSFQQPNSHPFPHSPNSSYPNSP- 196

Query: 282 SALASSEDLQPPSPSSSGSGLPGQAPPCYAPTYFPPGEKP 321
               SS    P SP+SS  G P Q P    P  + P E P
Sbjct: 197 ---GSSSSTYPHSPTSSDPGSPFQMPADTPPPAYLPPEDP 233


>gi|5174509 Sma- and Mad-related protein 1 [Homo sapiens]
          Length = 465

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 32/100 (32%), Positives = 41/100 (41%), Gaps = 19/100 (19%)

Query: 235 VPPQTLYNPAQQILAYAGFR-------------LTPEPVPTCSSYPLPLQPCSRFPVAPS 281
           VP  + YNP   +LA   FR               P+     +S+P P  P S +P +P 
Sbjct: 140 VPRHSEYNPQHSLLAQ--FRNLGQNEPHMPLNATFPDSFQQPNSHPFPHSPNSSYPNSP- 196

Query: 282 SALASSEDLQPPSPSSSGSGLPGQAPPCYAPTYFPPGEKP 321
               SS    P SP+SS  G P Q P    P  + P E P
Sbjct: 197 ---GSSSSTYPHSPTSSDPGSPFQMPADTPPPAYLPPEDP 233


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 25/73 (34%), Positives = 34/73 (46%), Gaps = 6/73 (8%)

Query: 251 AGFRLTPEPVPTCSSYPLPLQPCSRFPVAPSSALASSEDLQPPSPSSSGSGLPGQAPPCY 310
           +G +  P P P  ++ PLP        + PS  LA+   L PPSPS+  S     +PP  
Sbjct: 310 SGTKARPVPPPDNAATPLPAT------LPPSPPLATPLPLAPPSPSAPPSLQTLPSPPAT 363

Query: 311 APTYFPPGEKPPP 323
            P+  PP    PP
Sbjct: 364 PPSQAPPSMTTPP 376



 Score = 37.0 bits (84), Expect = 0.024
 Identities = 36/113 (31%), Positives = 45/113 (39%), Gaps = 14/113 (12%)

Query: 225 PLSQLAYGPAVPPQT-LYNPAQQILAYAGFRLTPEPVPTCSSYPL--PLQPCSRFPVAPS 281
           PL      PA PP + L  P+ Q        L   P     S P+  P  P +  PV+PS
Sbjct: 629 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 688

Query: 282 S--------ALASSEDLQPPSPSSSGSGLPGQAPPCYAPTYFPPGEKPPPYAP 326
           +        +LA+     PPSP +S    P   PP  AP   PP   PP   P
Sbjct: 689 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP---PPLAAPPLQVP 738



 Score = 37.0 bits (84), Expect = 0.024
 Identities = 34/112 (30%), Positives = 42/112 (37%), Gaps = 15/112 (13%)

Query: 224 VPLSQLAYGPAVPPQTLYNPAQQILAY--AGFRLTPEPVPTCSSYPLPLQPCSRFPVAPS 281
           +P+S LA  P   P  L  P  Q L    A F   P   P   S  LP+ P +  P    
Sbjct: 776 LPMSPLAKPPPQAPPALATPPLQALPSPPASF---PGQAPFSPSASLPMSPLATPPPQAP 832

Query: 282 SALASSEDLQPPSPSSSGSGLPGQAPPCYAP----------TYFPPGEKPPP 323
             LA+     PPSP +S +    + PP   P              PG  PPP
Sbjct: 833 PVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPP 884



 Score = 36.6 bits (83), Expect = 0.031
 Identities = 34/106 (32%), Positives = 46/106 (43%), Gaps = 13/106 (12%)

Query: 224 VPLSQLAYGPAVPPQTLYNPAQQILAYAGFRLTPEPVPTCSSYPLPLQPCSRFPVAPSSA 283
           VP S  A  P  P  T       +LA    ++ P P  +     LP+ P ++ P     A
Sbjct: 737 VPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPAS-----LPMSPLAKPPPQAPPA 791

Query: 284 LASSEDLQPPSPSSSGSGLPGQAPPCYAPTY---FPPGEKPPPYAP 326
           LA+      PSP +S    PGQAP  ++P+      P   PPP AP
Sbjct: 792 LATPPLQALPSPPAS---FPGQAP--FSPSASLPMSPLATPPPQAP 832



 Score = 33.5 bits (75), Expect = 0.26
 Identities = 29/100 (29%), Positives = 38/100 (38%), Gaps = 7/100 (7%)

Query: 225 PLSQLAYGPAVPPQTLYNPAQQILAYAGFRLTPEPVPTCSSYPLPLQPCSRFPVAPSSAL 284
           P S  A  P  P  T  + A   LA    ++ P P  +      P+ P +  P      L
Sbjct: 676 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP-----PMSPSATPPPQAPPPL 730

Query: 285 ASSEDLQPPSPSSSGSGLPGQAPPCYAPTYF--PPGEKPP 322
           A+     PPSP +S    P   PP   P     PP + PP
Sbjct: 731 AAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPP 770



 Score = 30.0 bits (66), Expect = 2.9
 Identities = 38/138 (27%), Positives = 45/138 (32%), Gaps = 35/138 (25%)

Query: 217 LGAFKDMVPLSQLAYGPA------------VPPQTLYNPAQQILAYAGFRLTPEPVPTCS 264
           L +     PLS L   P              PP +L  P  + L      L P P+ T S
Sbjct: 495 LASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLP----SLAPPPLQTAS 550

Query: 265 SY----PLPLQPCSRFPVAPSSALASSEDLQPPSPSSSGSGLPGQAPPCYA--------- 311
           +      L   PC      P  A  S     PP   SS +  P QAPP  A         
Sbjct: 551 APLTTPHLETPPCPA--PCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPS 608

Query: 312 ----PTYFPPGEKPPPYA 325
               P   PP + PP  A
Sbjct: 609 PPLSPLATPPPQAPPXLA 626



 Score = 28.9 bits (63), Expect = 6.5
 Identities = 32/117 (27%), Positives = 38/117 (32%), Gaps = 27/117 (23%)

Query: 225 PLSQLAYGPAVPPQTLYNPAQQILAYAGFRLTPEPVPTCSSYPL------PLQPCSRFPV 278
           P S L   P   P ++  P             P+  P  +S PL      PL P +  P 
Sbjct: 572 PPSPLTTPPPETPSSIATPP------------PQAPPALASPPLQGLPSPPLSPLATPPP 619

Query: 279 APSSALASSEDLQPPSPSSSGSGLPGQAPPCYAPTY---------FPPGEKPPPYAP 326
                LA      PPSP +S    P   P   AP           F P   PP  AP
Sbjct: 620 QAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAP 676


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 39/117 (33%), Positives = 49/117 (41%), Gaps = 15/117 (12%)

Query: 225 PLSQLAYGPAVPPQT-LYNPAQQILAYAGFRLTPEPVPTCSSYPL--PLQPCSRFPVAPS 281
           PL      PA PP + L  P+ Q        L   P     S P+  P  P +  PV+PS
Sbjct: 404 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 463

Query: 282 S--------ALASSEDLQPPSPSSSGSGLPGQAPPCYAPTYF--PPGE--KPPPYAP 326
           +        +LA+     PPSP +S    P   PP  AP     PP +  KPPP AP
Sbjct: 464 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAP 520



 Score = 34.7 bits (78), Expect = 0.12
 Identities = 34/111 (30%), Positives = 40/111 (36%), Gaps = 15/111 (13%)

Query: 225 PLSQLAYGPAVPPQTLYNPAQQILAY--AGFRLTPEPVPTCSSYPLPLQPCSRFPVAPSS 282
           P  QLA  P   P  L  P  Q L    A F   P   P   S  LP+ P +  P     
Sbjct: 508 PPLQLAKPPPQAPPALATPPLQALPSPPASF---PGQAPFSPSASLPMSPLATPPPQAPP 564

Query: 283 ALASSEDLQPPSPSSSGSGLPGQAPPCYAP----------TYFPPGEKPPP 323
            LA+     PPSP +S +    + PP   P              PG  PPP
Sbjct: 565 VLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPP 615



 Score = 31.2 bits (69), Expect = 1.3
 Identities = 37/115 (32%), Positives = 43/115 (37%), Gaps = 13/115 (11%)

Query: 225 PLSQLAYGPAVPP--QTLYNPAQQILAYAGFRL-TPEPVPTCSSYPLP-LQPCSRFPVAP 280
           PL      P+ PP  QTL +P     + A   L +P    T S  P P L P +  P   
Sbjct: 337 PLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA 396

Query: 281 SSALASSEDLQPPSPSSSGSGLPGQAPPCYAPTY---------FPPGEKPPPYAP 326
             ALA      PPSP +S    P   P   AP           F P   PP  AP
Sbjct: 397 PPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAP 451



 Score = 28.9 bits (63), Expect = 6.5
 Identities = 18/58 (31%), Positives = 25/58 (43%)

Query: 256 TPEPVPTCSSYPLPLQPCSRFPVAPSSALASSEDLQPPSPSSSGSGLPGQAPPCYAPT 313
           TP P     S   P  P +    + +  LA+   L PPSPS+  S     +PP   P+
Sbjct: 306 TPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPS 363



 Score = 28.5 bits (62), Expect = 8.5
 Identities = 24/99 (24%), Positives = 39/99 (39%), Gaps = 7/99 (7%)

Query: 225 PLSQLAYGPA-VPPQTLYNPAQQILAYAGFRLTPEPVPTCSSYPLPLQPCSRFPVAPSSA 283
           PL  L   PA  P Q  ++P+      A   ++P   P   + P+   P  + P +P ++
Sbjct: 527 PLQALPSPPASFPGQAPFSPS------ASLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS 580

Query: 284 LASSEDLQPPSPSSSGSGLPGQAPPCYAPTYFPPGEKPP 322
                  +PP+P    S    +     AP   PP  + P
Sbjct: 581 PTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 619


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 39/117 (33%), Positives = 49/117 (41%), Gaps = 15/117 (12%)

Query: 225 PLSQLAYGPAVPPQT-LYNPAQQILAYAGFRLTPEPVPTCSSYPL--PLQPCSRFPVAPS 281
           PL      PA PP + L  P+ Q        L   P     S P+  P  P +  PV+PS
Sbjct: 365 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 424

Query: 282 S--------ALASSEDLQPPSPSSSGSGLPGQAPPCYAPTYF--PPGE--KPPPYAP 326
           +        +LA+     PPSP +S    P   PP  AP     PP +  KPPP AP
Sbjct: 425 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAP 481



 Score = 34.7 bits (78), Expect = 0.12
 Identities = 34/111 (30%), Positives = 40/111 (36%), Gaps = 15/111 (13%)

Query: 225 PLSQLAYGPAVPPQTLYNPAQQILAY--AGFRLTPEPVPTCSSYPLPLQPCSRFPVAPSS 282
           P  QLA  P   P  L  P  Q L    A F   P   P   S  LP+ P +  P     
Sbjct: 469 PPLQLAKPPPQAPPALATPPLQALPSPPASF---PGQAPFSPSASLPMSPLATPPPQAPP 525

Query: 283 ALASSEDLQPPSPSSSGSGLPGQAPPCYAP----------TYFPPGEKPPP 323
            LA+     PPSP +S +    + PP   P              PG  PPP
Sbjct: 526 VLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPP 576



 Score = 30.0 bits (66), Expect = 2.9
 Identities = 35/107 (32%), Positives = 41/107 (38%), Gaps = 13/107 (12%)

Query: 233 PAVPP--QTLYNPAQQILAYAGFRL-TPEPVPTCSSYPLP-LQPCSRFPVAPSSALASSE 288
           P+ PP  QTL +P     + A   L +P    T S  P P L P +  P     ALA   
Sbjct: 306 PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPP 365

Query: 289 DLQPPSPSSSGSGLPGQAPPCYAPTY---------FPPGEKPPPYAP 326
              PPSP +S    P   P   AP           F P   PP  AP
Sbjct: 366 LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAP 412



 Score = 28.5 bits (62), Expect = 8.5
 Identities = 24/99 (24%), Positives = 39/99 (39%), Gaps = 7/99 (7%)

Query: 225 PLSQLAYGPA-VPPQTLYNPAQQILAYAGFRLTPEPVPTCSSYPLPLQPCSRFPVAPSSA 283
           PL  L   PA  P Q  ++P+      A   ++P   P   + P+   P  + P +P ++
Sbjct: 488 PLQALPSPPASFPGQAPFSPS------ASLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS 541

Query: 284 LASSEDLQPPSPSSSGSGLPGQAPPCYAPTYFPPGEKPP 322
                  +PP+P    S    +     AP   PP  + P
Sbjct: 542 PTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 580


>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
          Length = 1263

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 36/137 (26%), Positives = 52/137 (37%), Gaps = 29/137 (21%)

Query: 212 ITAAVLGAFKDMVPLSQLAYG--PAVPPQTLYNPAQQILAYAGFRLTPEPVPTCSSYPLP 269
           +T  +  A K+M  LS  A    P+VP +    PA  +   +G  + P P P  S+ P P
Sbjct: 542 LTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPP 601

Query: 270 LQP------------CSRFP--------VAPSSALASSEDLQPPSPSSSGSGLPGQAPPC 309
             P            C   P        ++P   L+    + PP P   G G+P      
Sbjct: 602 PPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIP------ 655

Query: 310 YAPTYFPPGEKPPPYAP 326
            +P+  P G   PP  P
Sbjct: 656 -SPSSLPGGTAIPPPPP 671



 Score = 34.3 bits (77), Expect = 0.15
 Identities = 25/95 (26%), Positives = 34/95 (35%), Gaps = 2/95 (2%)

Query: 233 PAVPPQTLYNPAQQILAYAGFRLTPEPVPTCSSYPLPLQPCSRFPVAPSSALASSEDLQP 292
           P++P  T  +P   +   A     P P+P     P P        + P   L  S  + P
Sbjct: 622 PSLPGGTAISPPPPLSGDATIP-PPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPP 680

Query: 293 PSPS-SSGSGLPGQAPPCYAPTYFPPGEKPPPYAP 326
           P P     +G+P   PP       PP   P P  P
Sbjct: 681 PPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGP 715



 Score = 33.1 bits (74), Expect = 0.34
 Identities = 21/66 (31%), Positives = 26/66 (39%), Gaps = 3/66 (4%)

Query: 259 PVPTCSSYPLPLQPCSRFPVAPSSALASSEDLQPPSPSSSGSGLPGQAPPCYAPTYFPPG 318
           P  T    P PL   +R P  P     S+    PP P    +G+P   PP       PP 
Sbjct: 661 PGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPP- 719

Query: 319 EKPPPY 324
             PPP+
Sbjct: 720 --PPPF 723



 Score = 32.3 bits (72), Expect = 0.59
 Identities = 31/107 (28%), Positives = 37/107 (34%), Gaps = 28/107 (26%)

Query: 227 SQLAYGPAVPPQT-------LYNPAQQILAYAGFRLTPEPVPTCSSYPLPLQPCSRFPVA 279
           S L  G A+PP         +  P   +   AG    P P+P  +  P P  P    P  
Sbjct: 658 SSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGI 717

Query: 280 PSSALASSEDLQPPSPSSSGSGLPGQAPPCYAPTYFPPGEKPPPYAP 326
           P           PP P   G G+P   PP       PPG   PP  P
Sbjct: 718 P-----------PPPPFPGGPGIP---PP-------PPGMGMPPPPP 743



 Score = 30.0 bits (66), Expect = 2.9
 Identities = 31/108 (28%), Positives = 39/108 (36%), Gaps = 9/108 (8%)

Query: 225 PLSQLAYGPAVPP--QTLYNPAQQILAYAGFRLTPEPVPTCSSYPLPLQPC---SRFPVA 279
           PLS  A  P  PP  + +  P+   L        P P+P  +  P P  P    +  P  
Sbjct: 635 PLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPP 694

Query: 280 PSSALASSEDLQPPSPSSSGSGLPGQAPPCYAPTYFPP----GEKPPP 323
           P      +    PP P   G G+P   P    P   PP    G  PPP
Sbjct: 695 PPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPP 742


>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
          Length = 1272

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 36/137 (26%), Positives = 52/137 (37%), Gaps = 29/137 (21%)

Query: 212 ITAAVLGAFKDMVPLSQLAYG--PAVPPQTLYNPAQQILAYAGFRLTPEPVPTCSSYPLP 269
           +T  +  A K+M  LS  A    P+VP +    PA  +   +G  + P P P  S+ P P
Sbjct: 551 LTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPP 610

Query: 270 LQP------------CSRFP--------VAPSSALASSEDLQPPSPSSSGSGLPGQAPPC 309
             P            C   P        ++P   L+    + PP P   G G+P      
Sbjct: 611 PPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIP------ 664

Query: 310 YAPTYFPPGEKPPPYAP 326
            +P+  P G   PP  P
Sbjct: 665 -SPSSLPGGTAIPPPPP 680



 Score = 34.3 bits (77), Expect = 0.15
 Identities = 25/95 (26%), Positives = 34/95 (35%), Gaps = 2/95 (2%)

Query: 233 PAVPPQTLYNPAQQILAYAGFRLTPEPVPTCSSYPLPLQPCSRFPVAPSSALASSEDLQP 292
           P++P  T  +P   +   A     P P+P     P P        + P   L  S  + P
Sbjct: 631 PSLPGGTAISPPPPLSGDATIP-PPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPP 689

Query: 293 PSPS-SSGSGLPGQAPPCYAPTYFPPGEKPPPYAP 326
           P P     +G+P   PP       PP   P P  P
Sbjct: 690 PPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGP 724



 Score = 33.1 bits (74), Expect = 0.34
 Identities = 21/66 (31%), Positives = 26/66 (39%), Gaps = 3/66 (4%)

Query: 259 PVPTCSSYPLPLQPCSRFPVAPSSALASSEDLQPPSPSSSGSGLPGQAPPCYAPTYFPPG 318
           P  T    P PL   +R P  P     S+    PP P    +G+P   PP       PP 
Sbjct: 670 PGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPP- 728

Query: 319 EKPPPY 324
             PPP+
Sbjct: 729 --PPPF 732



 Score = 32.3 bits (72), Expect = 0.59
 Identities = 31/107 (28%), Positives = 37/107 (34%), Gaps = 28/107 (26%)

Query: 227 SQLAYGPAVPPQT-------LYNPAQQILAYAGFRLTPEPVPTCSSYPLPLQPCSRFPVA 279
           S L  G A+PP         +  P   +   AG    P P+P  +  P P  P    P  
Sbjct: 667 SSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGI 726

Query: 280 PSSALASSEDLQPPSPSSSGSGLPGQAPPCYAPTYFPPGEKPPPYAP 326
           P           PP P   G G+P   PP       PPG   PP  P
Sbjct: 727 P-----------PPPPFPGGPGIP---PP-------PPGMGMPPPPP 752



 Score = 30.0 bits (66), Expect = 2.9
 Identities = 31/108 (28%), Positives = 39/108 (36%), Gaps = 9/108 (8%)

Query: 225 PLSQLAYGPAVPP--QTLYNPAQQILAYAGFRLTPEPVPTCSSYPLPLQPC---SRFPVA 279
           PLS  A  P  PP  + +  P+   L        P P+P  +  P P  P    +  P  
Sbjct: 644 PLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPP 703

Query: 280 PSSALASSEDLQPPSPSSSGSGLPGQAPPCYAPTYFPP----GEKPPP 323
           P      +    PP P   G G+P   P    P   PP    G  PPP
Sbjct: 704 PPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPP 751


>gi|47778931 SMAD, mothers against DPP homolog 5 [Homo sapiens]
          Length = 465

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 13/68 (19%)

Query: 257 PEPVPTCSSYPLPLQPCSRFPVAPSSALASSEDLQPPSPSSSGSG----LPGQAPPCYAP 312
           P+     ++ P PL P S +P +P+S+        P SP+SSG G    LP   PP   P
Sbjct: 174 PDSFHQPNNTPFPLSPNSPYPPSPASST------YPNSPASSGPGSPFQLPADTPP---P 224

Query: 313 TYFPPGEK 320
            Y PP ++
Sbjct: 225 AYMPPDDQ 232


>gi|47778929 SMAD, mothers against DPP homolog 5 [Homo sapiens]
          Length = 465

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 13/68 (19%)

Query: 257 PEPVPTCSSYPLPLQPCSRFPVAPSSALASSEDLQPPSPSSSGSG----LPGQAPPCYAP 312
           P+     ++ P PL P S +P +P+S+        P SP+SSG G    LP   PP   P
Sbjct: 174 PDSFHQPNNTPFPLSPNSPYPPSPASST------YPNSPASSGPGSPFQLPADTPP---P 224

Query: 313 TYFPPGEK 320
            Y PP ++
Sbjct: 225 AYMPPDDQ 232


>gi|47778925 SMAD, mothers against DPP homolog 5 [Homo sapiens]
          Length = 465

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 13/68 (19%)

Query: 257 PEPVPTCSSYPLPLQPCSRFPVAPSSALASSEDLQPPSPSSSGSG----LPGQAPPCYAP 312
           P+     ++ P PL P S +P +P+S+        P SP+SSG G    LP   PP   P
Sbjct: 174 PDSFHQPNNTPFPLSPNSPYPPSPASST------YPNSPASSGPGSPFQLPADTPP---P 224

Query: 313 TYFPPGEK 320
            Y PP ++
Sbjct: 225 AYMPPDDQ 232


>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
            sapiens]
          Length = 1636

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 33/112 (29%), Positives = 43/112 (38%), Gaps = 11/112 (9%)

Query: 225  PLSQLAYGPA---------VPPQTLYNPAQQILAYAGFRLTPEPVPTCSSYPLPLQPCSR 275
            P   LAYGPA           P T+  P+    +     L P P P+    P+P +P + 
Sbjct: 1045 PHPPLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSPHLVPSPAPSPGPGPVPPRPPAA 1104

Query: 276  FPVAPSSALASSEDLQPPSPSS--SGSGLPGQAPPCYAPTYFPPGEKPPPYA 325
             P       A++ DL   SP S   G+  PG   P   PT     E   P A
Sbjct: 1105 EPPPCLRRGAAAADLLSSSPESQHGGTQSPGGGQPLLQPTKVDAAEGRRPQA 1156



 Score = 29.3 bits (64), Expect = 5.0
 Identities = 36/111 (32%), Positives = 43/111 (38%), Gaps = 28/111 (25%)

Query: 233  PAVPPQTLYNP-------AQQILAY--------AGF---RLTPEPVPTCSSYPLPLQPCS 274
            P  PPQ L  P        Q I A         AGF   R+ P+P P    +P P    +
Sbjct: 911  PVPPPQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFPAPRIGPQPQP----HPQPHPSQA 966

Query: 275  RFPVAPSSALASSEDLQPPS--PSSSGSGLPGQAPPCYAPTYFPPGEKPPP 323
              P  P   L     LQ P   P  +   LP Q+P  YAP     G+ PPP
Sbjct: 967  FGPQPPQQPLP----LQHPHLFPPQAPGLLPPQSPYPYAPQPGVLGQPPPP 1013


>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
           sapiens]
          Length = 483

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 34/101 (33%), Positives = 45/101 (44%), Gaps = 14/101 (13%)

Query: 232 GPAVPPQT--LYNPAQQILAYAGFRLTPE----PVPTCSSYPLPLQPCSRFPVAPSSALA 285
           GP +PP +  L N ++   A+   R  P     P P   + P P  P    P  PSS+  
Sbjct: 142 GPLIPPASPRLGNTSE---AHGAARTAPPRPNVPAPPPPTPPPPPPPLP--PPLPSSSPI 196

Query: 286 SSEDLQPPSPSSSGSGLPGQAPPCYAPTYFPPGEKPPPYAP 326
            +  + PP P + G+ LP  APP   P   PP   PPP  P
Sbjct: 197 KTPLVSPPGPLTKGN-LPVVAPP--VPCAPPPPPPPPPPTP 234



 Score = 30.0 bits (66), Expect = 2.9
 Identities = 30/104 (28%), Positives = 41/104 (39%), Gaps = 20/104 (19%)

Query: 233 PAVPPQTLYNPAQQILAYAGFRLTPEPVPTCSSYPLPLQPCSRFPVAPSSALASSEDLQ- 291
           P +PP ++ +        A   L P P P      LPL P   +P   +   + ++D Q 
Sbjct: 235 PPLPPASVLSDKAVKPQLAPLHLPPIPPP------LPLLPPCGYPGLKAEPASPAQDAQE 288

Query: 292 PPSP---------SSSGSGLPGQAPPCYAPTYFPPGEKPPPYAP 326
           PP+P          S  + LP  APP   P      E PPP  P
Sbjct: 289 PPAPPPPLPPYASCSPRASLP--APP--LPGVNSSSETPPPLPP 328


>gi|24430132 WW domain binding protein 2 [Homo sapiens]
          Length = 261

 Score = 38.9 bits (89), Expect = 0.006
 Identities = 29/94 (30%), Positives = 41/94 (43%), Gaps = 10/94 (10%)

Query: 233 PAVPPQTLYNPAQQILAYAGFRLTPEPVPTCSSYPLPLQPCSRFPVAPSSALASSEDLQP 292
           P  PP   + P   ++  A   + P P P    YP P++P    P  PS+  A ++  + 
Sbjct: 171 PYPPPPPEFYPGPPMMDGAMGYVQPPPPP----YPGPMEPPVSGPDVPSTPAAEAKAAE- 225

Query: 293 PSPSSSGSGLPGQAPPCYAPTYFPPGEKPPPYAP 326
              ++S    PG     Y PT  PP   PPPY P
Sbjct: 226 --AAASAYYNPGNPHNVYMPTSQPP---PPPYYP 254


>gi|157168329 formin 1 [Homo sapiens]
          Length = 1196

 Score = 38.5 bits (88), Expect = 0.008
 Identities = 36/110 (32%), Positives = 42/110 (38%), Gaps = 7/110 (6%)

Query: 215 AVLGAFKDMVPLSQLAYGPAVPPQTLYNPAQQILAYAGFRLTPEPVPTCSSYPLPLQPCS 274
           A L   + M    Q A  P  PP ++  P             P   P  +  PLP  P  
Sbjct: 629 AALQPMEGMASNQQKALPP--PPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPP 686

Query: 275 RFPVAP-SSALASSEDLQPPSPSSSGSGLPGQAPPCYAPTYFPPGEKPPP 323
             P+ P SSA        PP P+S     PG  PP  AP   PPG  PPP
Sbjct: 687 PPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGGPPP--APP--PPGLAPPP 732



 Score = 31.2 bits (69), Expect = 1.3
 Identities = 24/79 (30%), Positives = 28/79 (35%), Gaps = 7/79 (8%)

Query: 255 LTPEPVPTCSSYPLPLQPCSRFPVAPSSALASSEDLQPP-------SPSSSGSGLPGQAP 307
           L P P       PLP    S  P  P   +++   L PP        P SS    P   P
Sbjct: 645 LPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPP 704

Query: 308 PCYAPTYFPPGEKPPPYAP 326
           P    +  PP    PP AP
Sbjct: 705 PPLPNSPAPPNPGGPPPAP 723


>gi|9945318 MAX binding protein [Homo sapiens]
          Length = 582

 Score = 38.5 bits (88), Expect = 0.008
 Identities = 30/105 (28%), Positives = 41/105 (39%), Gaps = 3/105 (2%)

Query: 224 VPLSQLAYGPAVPPQTLYNPAQQILAYAGFRLTPEPVPTCSSYPLPLQPCSRFPVAPSSA 283
           +PLS  A  PA PP         ++       +P+P+P     P   QP    P  P+  
Sbjct: 65  LPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQPLPLAPRQPALV 124

Query: 284 LASSEDLQPPSPSSSGSGLPGQAP--PCYAPTYFPPGEKPPPYAP 326
            A    ++ P+P  S   +P  AP  P    T  PP   P P  P
Sbjct: 125 GAPGLSIKEPAPLPSRPQVPTPAPLLPDSKAT-IPPNGSPKPLQP 168


>gi|22547176 oxysterol binding protein-like 9 isoform f [Homo
           sapiens]
          Length = 746

 Score = 38.1 bits (87), Expect = 0.011
 Identities = 31/100 (31%), Positives = 49/100 (49%), Gaps = 13/100 (13%)

Query: 213 TAAVLGAFKDMVPLSQLAYGPAVPPQTLYNPA--QQILAYAGFR--LTPEPVPTCSSYPL 268
           T +++ + K  + L Q+A     P   +Y P+  + +++    +  L PEPV  C S   
Sbjct: 186 TNSMVESIKHCIVLLQIAKSTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQR 245

Query: 269 PLQPCSRFPVAPSSALASSEDLQPPSPSSSGSGLPGQAPP 308
           P    S  PV P   LA+    Q P+P+S+GS   G +PP
Sbjct: 246 P----SSLPVGP--VLATLGHHQTPTPNSTGS---GHSPP 276


>gi|22547173 oxysterol binding protein-like 9 isoform d [Homo
           sapiens]
          Length = 723

 Score = 38.1 bits (87), Expect = 0.011
 Identities = 31/100 (31%), Positives = 49/100 (49%), Gaps = 13/100 (13%)

Query: 213 TAAVLGAFKDMVPLSQLAYGPAVPPQTLYNPA--QQILAYAGFR--LTPEPVPTCSSYPL 268
           T +++ + K  + L Q+A     P   +Y P+  + +++    +  L PEPV  C S   
Sbjct: 163 TNSMVESIKHCIVLLQIAKSTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQR 222

Query: 269 PLQPCSRFPVAPSSALASSEDLQPPSPSSSGSGLPGQAPP 308
           P    S  PV P   LA+    Q P+P+S+GS   G +PP
Sbjct: 223 P----SSLPVGP--VLATLGHHQTPTPNSTGS---GHSPP 253


>gi|22547171 oxysterol binding protein-like 9 isoform c [Homo
           sapiens]
          Length = 626

 Score = 38.1 bits (87), Expect = 0.011
 Identities = 31/100 (31%), Positives = 49/100 (49%), Gaps = 13/100 (13%)

Query: 213 TAAVLGAFKDMVPLSQLAYGPAVPPQTLYNPA--QQILAYAGFR--LTPEPVPTCSSYPL 268
           T +++ + K  + L Q+A     P   +Y P+  + +++    +  L PEPV  C S   
Sbjct: 66  TNSMVESIKHCIVLLQIAKSTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQR 125

Query: 269 PLQPCSRFPVAPSSALASSEDLQPPSPSSSGSGLPGQAPP 308
           P    S  PV P   LA+    Q P+P+S+GS   G +PP
Sbjct: 126 P----SSLPVGP--VLATLGHHQTPTPNSTGS---GHSPP 156


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.140    0.445 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,556,652
Number of Sequences: 37866
Number of extensions: 849159
Number of successful extensions: 6739
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 102
Number of HSP's successfully gapped in prelim test: 391
Number of HSP's that attempted gapping in prelim test: 5057
Number of HSP's gapped (non-prelim): 1715
length of query: 326
length of database: 18,247,518
effective HSP length: 103
effective length of query: 223
effective length of database: 14,347,320
effective search space: 3199452360
effective search space used: 3199452360
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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