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Search of human proteins with 32528301
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|32528301 EPH receptor B4 precursor [Homo sapiens]
(987 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|32528301 EPH receptor B4 precursor [Homo sapiens] 2011 0.0
gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens] 1143 0.0
gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo sap... 1092 0.0
gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo sapi... 1091 0.0
gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens] 1084 0.0
gi|4758280 ephrin receptor EphA4 [Homo sapiens] 961 0.0
gi|4758282 ephrin receptor EphA7 [Homo sapiens] 942 0.0
gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sap... 925 0.0
gi|21361241 ephrin receptor EphA3 isoform a precursor [Homo sapi... 924 0.0
gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sap... 917 0.0
gi|145312251 EPH receptor A6 isoform a [Homo sapiens] 896 0.0
gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo sapi... 850 0.0
gi|32967311 ephrin receptor EphA2 [Homo sapiens] 814 0.0
gi|194097332 ephrin receptor EphB6 precursor [Homo sapiens] 784 0.0
gi|150456460 EPH receptor A10 isofom 3 [Homo sapiens] 731 0.0
gi|221316650 ephrin receptor EphA1 [Homo sapiens] 707 0.0
gi|32967314 ephrin receptor EphA3 isoform b precursor [Homo sapi... 384 e-106
gi|55770892 ephrin receptor EphA8 isoform 2 precursor [Homo sapi... 314 3e-85
gi|27886593 PTK2 protein tyrosine kinase 2 isoform b [Homo sapiens] 225 1e-58
gi|24476013 PTK2 protein tyrosine kinase 2 isoform a [Homo sapiens] 225 1e-58
gi|30795229 hemopoietic cell kinase isoform p61HCK [Homo sapiens] 223 5e-58
gi|4885661 viral oncogene yes-1 homolog 1 [Homo sapiens] 222 2e-57
gi|38202217 proto-oncogene tyrosine-protein kinase SRC [Homo sap... 221 2e-57
gi|4885609 proto-oncogene tyrosine-protein kinase SRC [Homo sapi... 221 2e-57
gi|4503823 protein-tyrosine kinase fyn isoform a [Homo sapiens] 218 3e-56
gi|112789548 lymphocyte-specific protein tyrosine kinase precurs... 216 1e-55
gi|112789546 lymphocyte-specific protein tyrosine kinase precurs... 216 1e-55
gi|162287326 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog ... 216 1e-55
gi|4505055 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog is... 216 1e-55
gi|23510362 protein-tyrosine kinase fyn isoform b [Homo sapiens] 214 2e-55
>gi|32528301 EPH receptor B4 precursor [Homo sapiens]
Length = 987
Score = 2011 bits (5211), Expect = 0.0
Identities = 987/987 (100%), Positives = 987/987 (100%)
Query: 1 MELRVLLCWASLAAALEETLLNTKLETADLKWVTFPQVDGQWEELSGLDEEQHSVRTYEV 60
MELRVLLCWASLAAALEETLLNTKLETADLKWVTFPQVDGQWEELSGLDEEQHSVRTYEV
Sbjct: 1 MELRVLLCWASLAAALEETLLNTKLETADLKWVTFPQVDGQWEELSGLDEEQHSVRTYEV 60
Query: 61 CDVQRAPGQAHWLRTGWVPRRGAVHVYATLRFTMLECLSLPRAGRSCKETFTVFYYESDA 120
CDVQRAPGQAHWLRTGWVPRRGAVHVYATLRFTMLECLSLPRAGRSCKETFTVFYYESDA
Sbjct: 61 CDVQRAPGQAHWLRTGWVPRRGAVHVYATLRFTMLECLSLPRAGRSCKETFTVFYYESDA 120
Query: 121 DTATALTPAWMENPYIKVDTVAAEHLTRKRPGAEATGKVNVKTLRLGPLSKAGFYLAFQD 180
DTATALTPAWMENPYIKVDTVAAEHLTRKRPGAEATGKVNVKTLRLGPLSKAGFYLAFQD
Sbjct: 121 DTATALTPAWMENPYIKVDTVAAEHLTRKRPGAEATGKVNVKTLRLGPLSKAGFYLAFQD 180
Query: 181 QGACMALLSLHLFYKKCAQLTVNLTRFPETVPRELVVPVAGSCVVDAVPAPGPSPSLYCR 240
QGACMALLSLHLFYKKCAQLTVNLTRFPETVPRELVVPVAGSCVVDAVPAPGPSPSLYCR
Sbjct: 181 QGACMALLSLHLFYKKCAQLTVNLTRFPETVPRELVVPVAGSCVVDAVPAPGPSPSLYCR 240
Query: 241 EDGQWAEQPVTGCSCAPGFEAAEGNTKCRACAQGTFKPLSGEGSCQPCPANSHSNTIGSA 300
EDGQWAEQPVTGCSCAPGFEAAEGNTKCRACAQGTFKPLSGEGSCQPCPANSHSNTIGSA
Sbjct: 241 EDGQWAEQPVTGCSCAPGFEAAEGNTKCRACAQGTFKPLSGEGSCQPCPANSHSNTIGSA 300
Query: 301 VCQCRVGYFRARTDPRGAPCTTPPSAPRSVVSRLNGSSLHLEWSAPLESGGREDLTYALR 360
VCQCRVGYFRARTDPRGAPCTTPPSAPRSVVSRLNGSSLHLEWSAPLESGGREDLTYALR
Sbjct: 301 VCQCRVGYFRARTDPRGAPCTTPPSAPRSVVSRLNGSSLHLEWSAPLESGGREDLTYALR 360
Query: 361 CRECRPGGSCAPCGGDLTFDPGPRDLVEPWVVVRGLRPDFTYTFEVTALNGVSSLATGPV 420
CRECRPGGSCAPCGGDLTFDPGPRDLVEPWVVVRGLRPDFTYTFEVTALNGVSSLATGPV
Sbjct: 361 CRECRPGGSCAPCGGDLTFDPGPRDLVEPWVVVRGLRPDFTYTFEVTALNGVSSLATGPV 420
Query: 421 PFEPVNVTTDREVPPAVSDIRVTRSSPSSLSLAWAVPRAPSGAVLDYEVKYHEKGAEGPS 480
PFEPVNVTTDREVPPAVSDIRVTRSSPSSLSLAWAVPRAPSGAVLDYEVKYHEKGAEGPS
Sbjct: 421 PFEPVNVTTDREVPPAVSDIRVTRSSPSSLSLAWAVPRAPSGAVLDYEVKYHEKGAEGPS 480
Query: 481 SVRFLKTSENRAELRGLKRGASYLVQVRARSEAGYGPFGQEHHSQTQLDESEGWREQLAL 540
SVRFLKTSENRAELRGLKRGASYLVQVRARSEAGYGPFGQEHHSQTQLDESEGWREQLAL
Sbjct: 481 SVRFLKTSENRAELRGLKRGASYLVQVRARSEAGYGPFGQEHHSQTQLDESEGWREQLAL 540
Query: 541 IAGTAVVGVVLVLVVIVVAVLCLRKQSNGREAEYSDKHGQYLIGHGTKVYIDPFTYEDPN 600
IAGTAVVGVVLVLVVIVVAVLCLRKQSNGREAEYSDKHGQYLIGHGTKVYIDPFTYEDPN
Sbjct: 541 IAGTAVVGVVLVLVVIVVAVLCLRKQSNGREAEYSDKHGQYLIGHGTKVYIDPFTYEDPN 600
Query: 601 EAVREFAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRRE 660
EAVREFAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRRE
Sbjct: 601 EAVREFAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRRE 660
Query: 661 FLSEASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLNDGQFTVIQLVGM 720
FLSEASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLNDGQFTVIQLVGM
Sbjct: 661 FLSEASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLNDGQFTVIQLVGM 720
Query: 721 LRGIASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGG 780
LRGIASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGG
Sbjct: 721 LRGIASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGG 780
Query: 781 KIPIRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLP 840
KIPIRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLP
Sbjct: 781 KIPIRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLP 840
Query: 841 PPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKMIRNPASLKIVARENGGASHPLLD 900
PPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKMIRNPASLKIVARENGGASHPLLD
Sbjct: 841 PPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKMIRNPASLKIVARENGGASHPLLD 900
Query: 901 QRQPHYSAFGSVGEWLRAIKMGRYEESFAAAGFGSFELVSQISAEDLLRIGVTLAGHQKK 960
QRQPHYSAFGSVGEWLRAIKMGRYEESFAAAGFGSFELVSQISAEDLLRIGVTLAGHQKK
Sbjct: 901 QRQPHYSAFGSVGEWLRAIKMGRYEESFAAAGFGSFELVSQISAEDLLRIGVTLAGHQKK 960
Query: 961 ILASVQHMKSQAKPGTPGGTGGPAPQY 987
ILASVQHMKSQAKPGTPGGTGGPAPQY
Sbjct: 961 ILASVQHMKSQAKPGTPGGTGGPAPQY 987
>gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens]
Length = 998
Score = 1143 bits (2956), Expect = 0.0
Identities = 582/973 (59%), Positives = 718/973 (73%), Gaps = 24/973 (2%)
Query: 15 ALEETLLNTKLETADLKWVTFPQVDGQWEELSGLDEEQHSVRTYEVCDVQRAPGQAHWLR 74
ALEETL++TK T++L W + P+ WEE+SG DE + +RTY+VC+V R Q +WLR
Sbjct: 37 ALEETLMDTKWVTSELAWTSHPE--SGWEEVSGYDEAMNPIRTYQVCNV-RESSQNNWLR 93
Query: 75 TGWVPRRGAVHVYATLRFTMLECLSLPRAGRSCKETFTVFYYESDADTATALTPAWMENP 134
TG++ RR VY L+FT+ +C S+P SCKETF +FYYE+D+D A+A +P WMENP
Sbjct: 94 TGFIWRRDVQRVYVELKFTVRDCNSIPNIPGSCKETFNLFYYEADSDVASASSPFWMENP 153
Query: 135 YIKVDTVAAEHLTRKRPGAEATGKVNVKTLRLGPLSKAGFYLAFQDQGACMALLSLHLFY 194
Y+KVDT+A + + G+VN K GPLSKAGFYLAFQDQGACM+L+S+ FY
Sbjct: 154 YVKVDTIAPDESFSRLDA----GRVNTKVRSFGPLSKAGFYLAFQDQGACMSLISVRAFY 209
Query: 195 KKCAQLTVNLTRFPETV----PRELVVPVAGSCVVDAVPAPGPSPSLYCREDGQWAEQPV 250
KKCA T FPET+ P LV+ G+C+ +AV P LYC DG+W PV
Sbjct: 210 KKCASTTAGFALFPETLTGAEPTSLVI-APGTCIPNAVEVSVPL-KLYCNGDGEWMV-PV 266
Query: 251 TGCSCAPGFEAAEGNTKCRACAQGTFKPLSGEGSCQPCPANSHSNTIGSAVCQCRVGYFR 310
C+CA G E A ++CR C G++K GEG C PCP NS + + +++C C ++R
Sbjct: 267 GACTCATGHEPAAKESQCRPCPPGSYKAKQGEGPCLPCPPNSRTTSPAASICTCHNNFYR 326
Query: 311 ARTDPRGAPCTTPPSAPRSVVSRLNGSSLHLEWSAPLESGGREDLTYALRCRECRPGG-- 368
A +D + CTT PS PR V+S +N +SL LEWS P + GGR+DL Y + C++C G
Sbjct: 327 ADSDSADSACTTVPSPPRGVISNVNETSLILEWSEPRDLGGRDDLLYNVICKKCHGAGGA 386
Query: 369 -SCAPCGGDLTFDPGPRDLVEPWVVVRGLRPDFTYTFEVTALNGVSSLATGPVPFEPVNV 427
+C+ C ++ F P L E V + L YTFEV A+NGVS + P + VN+
Sbjct: 387 SACSRCDDNVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVNGVSGKSPLPPRYAAVNI 446
Query: 428 TTDREVPPAVSDIRVTRSSPSSLSLAWAVPRAPSGAVLDYEVKYHEKGAEGPSSVRFLKT 487
TT++ P V +R+ SS SSL+L+WA P P+G +LDYE+KY EK +EG +S + +
Sbjct: 447 TTNQAAPSEVPTLRLHSSSGSSLTLSWAPPERPNGVILDYEMKYFEK-SEGIAST--VTS 503
Query: 488 SENRAELRGLKRGASYLVQVRARSEAGYGPFGQEHHSQTQLDESEG---WREQLALIAGT 544
N +L GL+ A Y+VQVRAR+ AGYG + + +T + G +EQL LI G+
Sbjct: 504 QMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRPAEFETTSERGSGAQQLQEQLPLIVGS 563
Query: 545 AVVGVVLVLVVIVVAVLCLRKQSNGREAEYSDKHGQYLIGHGTKVYIDPFTYEDPNEAVR 604
A G+V V+ V+V+A++CLRKQ +G ++EY++K QY I G KVYIDPFTYEDPNEAVR
Sbjct: 564 ATAGLVFVVAVVVIAIVCLRKQRHGSDSEYTEKLQQY-IAPGMKVYIDPFTYEDPNEAVR 622
Query: 605 EFAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSE 664
EFAKEIDVS VKIEEVIGAGEFGEVCRGRLK PG++E VAIKTLK GYTERQRR+FLSE
Sbjct: 623 EFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYTERQRRDFLSE 682
Query: 665 ASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGI 724
ASIMGQF+HPNIIRLEGVVT S PVMILTEFMEN ALDSFLRLNDGQFTVIQLVGMLRGI
Sbjct: 683 ASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGI 742
Query: 725 ASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPI 784
A+GM+YL+EM+YVHRDLAARNILVNSNLVCKVSDFGLSRFLE++ SDPTYTSSLGGKIPI
Sbjct: 743 AAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPI 802
Query: 785 RWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPPD 844
RWTAPEAIA+RKFTSASD WSYGIVMWEVMS+GERPYWDMSNQDVINA+EQDYRLPPP D
Sbjct: 803 RWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMD 862
Query: 845 CPTSLHQLMLDCWQKDRNARPRFPQVVSALDKMIRNPASLKIVARENGGASHPLLDQRQP 904
CPT+LHQLMLDCW +DRN RP+F Q+V+ LDK+IRN ASLK++A G S PLLD+ P
Sbjct: 863 CPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAASLKVIASAQSGMSQPLLDRTVP 922
Query: 905 HYSAFGSVGEWLRAIKMGRYEESFAAAGFGSFELVSQISAEDLLRIGVTLAGHQKKILAS 964
Y+ F +VG+WL AIKMGRY+ESF +AGF SF+LV+Q++AEDLLRIGVTLAGHQKKIL+S
Sbjct: 923 DYTTFTTVGDWLDAIKMGRYKESFVSAGFASFDLVAQMTAEDLLRIGVTLAGHQKKILSS 982
Query: 965 VQHMKSQAKPGTP 977
+Q M+ Q P
Sbjct: 983 IQDMRLQMNQTLP 995
>gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo
sapiens]
Length = 986
Score = 1092 bits (2825), Expect = 0.0
Identities = 543/969 (56%), Positives = 705/969 (72%), Gaps = 15/969 (1%)
Query: 12 LAAALEETLLNTKLETADLKWVTFPQVDGQWEELSGLDEEQHSVRTYEVCDVQRAPGQAH 71
L AA+EETL+++ TA+L W+ P WEE+SG DE +++RTY+VC+V + Q +
Sbjct: 15 LLAAVEETLMDSTTATAELGWMVHPP--SGWEEVSGYDENMNTIRTYQVCNVFES-SQNN 71
Query: 72 WLRTGWVPRRGAVHVYATLRFTMLECLSLPRAGRSCKETFTVFYYESDADTATALTPAWM 131
WLRT ++ RRGA ++ ++F++ +C S+P SCKETF ++YYE+D D+AT P WM
Sbjct: 72 WLRTKFIRRRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDSATKTFPNWM 131
Query: 132 ENPYIKVDTVAAEHLTRKRPGAEATGKVNVKTLRLGPLSKAGFYLAFQDQGACMALLSLH 191
ENP++KVDT+AA+ + K+N + GP+S++GFYLAFQD G CM+L+++
Sbjct: 132 ENPWVKVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYGGCMSLIAVR 191
Query: 192 LFYKKCAQLTVNLTRFPETVP---RELVVPVAGSCVVDAVPAPGPSPSLYCREDGQWAEQ 248
+FY+KC ++ N F ET+ +V GSC+ +A P LYC DG+W
Sbjct: 192 VFYRKCPRIIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPI-KLYCNGDGEWLV- 249
Query: 249 PVTGCSCAPGFEAAEGNTKCRACAQGTFKPLSGEGSCQPCPANSHSNTIGSAVCQCRVGY 308
P+ C C GFEA E T CR C GTFK G+ +C CP NS + + G+ C CR GY
Sbjct: 250 PIGRCMCKAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNCVCRNGY 309
Query: 309 FRARTDPRGAPCTTPPSAPRSVVSRLNGSSLHLEWSAPLESGGREDLTYALRCRECRPG- 367
+RA DP PCTT PSAP++V+S +N +SL LEW+ P +SGGREDL Y + C+ C G
Sbjct: 310 YRADLDPLDMPCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICKSCGSGR 369
Query: 368 GSCAPCGGDLTFDPGPRDLVEPWVVVRGLRPDFTYTFEVTALNGVSSLATGPVPFEPVNV 427
G+C CG ++ + P L EP + + L YTFE+ A+NGV+ + F VN+
Sbjct: 370 GACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFASVNI 429
Query: 428 TTDREVPPAVSDIRVTRSSPSSLSLAWAVPRAPSGAVLDYEVKYHEKGAEGPSSVRFLKT 487
TT++ P AVS + + S++L+W+ P P+G +LDYE++Y+EK ++ +K+
Sbjct: 430 TTNQAAPSAVSIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEYNATA-IKS 488
Query: 488 SENRAELRGLKRGASYLVQVRARSEAGYGPFGQEHHSQT--QLDESEGWREQLALIAGTA 545
N ++GLK GA Y+ QVRAR+ AGYG + + + QT + + +E+L LI G++
Sbjct: 489 PTNTVTVQGLKAGAIYVFQVRARTVAGYGRYSGKMYFQTMTEAEYQTSIQEKLPLIIGSS 548
Query: 546 VVGVVLVLVVIVVAVLCLRKQSNGREAEYSDKHGQYLIGH---GTKVYIDPFTYEDPNEA 602
G+V ++ V+V+A++C R+ ++EY+DK Y GH G K+YIDPFTYEDPNEA
Sbjct: 549 AAGLVFLIAVVVIAIVCNRRGFERADSEYTDKLQHYTSGHMTPGMKIYIDPFTYEDPNEA 608
Query: 603 VREFAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFL 662
VREFAKEID+S VKIE+VIGAGEFGEVC G LK PGK+E VAIKTLK GYTE+QRR+FL
Sbjct: 609 VREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFL 668
Query: 663 SEASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLNDGQFTVIQLVGMLR 722
SEASIMGQF+HPN+I LEGVVT S PVMI+TEFMENG+LDSFLR NDGQFTVIQLVGMLR
Sbjct: 669 SEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLR 728
Query: 723 GIASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKI 782
GIA+GM+YLA+M+YVHRDLAARNILVNSNLVCKVSDFGLSRFLE+++SDPTYTS+LGGKI
Sbjct: 729 GIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKI 788
Query: 783 PIRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPP 842
PIRWTAPEAI +RKFTSASD WSYGIVMWEVMS+GERPYWDM+NQDVINAIEQDYRLPPP
Sbjct: 789 PIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPP 848
Query: 843 PDCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKMIRNPASLKIVARENGGASHPLLDQR 902
DCP++LHQLMLDCWQKDRN RP+F Q+V+ LDKMIRNP SLK +A + G + PLLD+
Sbjct: 849 MDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLSSGINLPLLDRT 908
Query: 903 QPHYSAFGSVGEWLRAIKMGRYEESFAAAGFGSFELVSQISAEDLLRIGVTLAGHQKKIL 962
P Y++F +V EWL AIKMG+Y+ESFA AGF SF++VSQ+ ED+LR+GVTLAGHQKKIL
Sbjct: 909 IPDYTSFNTVDEWLEAIKMGQYKESFANAGFTSFDVVSQMMMEDILRVGVTLAGHQKKIL 968
Query: 963 ASVQHMKSQ 971
S+Q M++Q
Sbjct: 969 NSIQVMRAQ 977
>gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo
sapiens]
Length = 987
Score = 1091 bits (2821), Expect = 0.0
Identities = 544/970 (56%), Positives = 707/970 (72%), Gaps = 16/970 (1%)
Query: 12 LAAALEETLLNTKLETADLKWVTFPQVDGQWEELSGLDEEQHSVRTYEVCDVQRAPGQAH 71
L AA+EETL+++ TA+L W+ P WEE+SG DE +++RTY+VC+V + Q +
Sbjct: 15 LLAAVEETLMDSTTATAELGWMVHPP--SGWEEVSGYDENMNTIRTYQVCNVFES-SQNN 71
Query: 72 WLRTGWVPRRGAVHVYATLRFTMLECLSLPRAGRSCKETFTVFYYESDADTATALTPAWM 131
WLRT ++ RRGA ++ ++F++ +C S+P SCKETF ++YYE+D D+AT P WM
Sbjct: 72 WLRTKFIRRRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDSATKTFPNWM 131
Query: 132 ENPYIKVDTVAAEHLTRKRPGAEATGKVNVKTLRLGPLSKAGFYLAFQDQGACMALLSLH 191
ENP++KVDT+AA+ + K+N + GP+S++GFYLAFQD G CM+L+++
Sbjct: 132 ENPWVKVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYGGCMSLIAVR 191
Query: 192 LFYKKCAQLTVNLTRFPETVP---RELVVPVAGSCVVDAVPAPGPSPSLYCREDGQWAEQ 248
+FY+KC ++ N F ET+ +V GSC+ +A P LYC DG+W
Sbjct: 192 VFYRKCPRIIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPI-KLYCNGDGEWLV- 249
Query: 249 PVTGCSCAPGFEAAEGNTKCRACAQGTFKPLSGEGSCQPCPANSHSNTIGSAVCQCRVGY 308
P+ C C GFEA E T CR C GTFK G+ +C CP NS + + G+ C CR GY
Sbjct: 250 PIGRCMCKAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNCVCRNGY 309
Query: 309 FRARTDPRGAPCTTPPSAPRSVVSRLNGSSLHLEWSAPLESGGREDLTYALRCRECRPG- 367
+RA DP PCTT PSAP++V+S +N +SL LEW+ P +SGGREDL Y + C+ C G
Sbjct: 310 YRADLDPLDMPCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICKSCGSGR 369
Query: 368 GSCAPCGGDLTFDPGPRDLVEPWVVVRGLRPDFTYTFEVTALNGVSSLATGPVPFEPVNV 427
G+C CG ++ + P L EP + + L YTFE+ A+NGV+ + F VN+
Sbjct: 370 GACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFASVNI 429
Query: 428 TTDREVPPAVSDIRVTRSSPSSLSLAWAVPRAPSGAVLDYEVKYHEKGAEGPSSVRFLKT 487
TT++ P AVS + + S++L+W+ P P+G +LDYE++Y+EK ++ +K+
Sbjct: 430 TTNQAAPSAVSIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEYNATA-IKS 488
Query: 488 SENRAELRGLKRGASYLVQVRARSEAGYGPFGQEHHSQT--QLDESEGWREQLALIAGTA 545
N ++GLK GA Y+ QVRAR+ AGYG + + + QT + + +E+L LI G++
Sbjct: 489 PTNTVTVQGLKAGAIYVFQVRARTVAGYGRYSGKMYFQTMTEAEYQTSIQEKLPLIIGSS 548
Query: 546 VVGVVLVLVVIVVAVLCLRKQSNGR-EAEYSDKHGQYLIGH---GTKVYIDPFTYEDPNE 601
G+V ++ V+V+A++C R++ R ++EY+DK Y GH G K+YIDPFTYEDPNE
Sbjct: 549 AAGLVFLIAVVVIAIVCNRRRGFERADSEYTDKLQHYTSGHMTPGMKIYIDPFTYEDPNE 608
Query: 602 AVREFAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREF 661
AVREFAKEID+S VKIE+VIGAGEFGEVC G LK PGK+E VAIKTLK GYTE+QRR+F
Sbjct: 609 AVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDF 668
Query: 662 LSEASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLNDGQFTVIQLVGML 721
LSEASIMGQF+HPN+I LEGVVT S PVMI+TEFMENG+LDSFLR NDGQFTVIQLVGML
Sbjct: 669 LSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGML 728
Query: 722 RGIASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGK 781
RGIA+GM+YLA+M+YVHRDLAARNILVNSNLVCKVSDFGLSRFLE+++SDPTYTS+LGGK
Sbjct: 729 RGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGK 788
Query: 782 IPIRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPP 841
IPIRWTAPEAI +RKFTSASD WSYGIVMWEVMS+GERPYWDM+NQDVINAIEQDYRLPP
Sbjct: 789 IPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPP 848
Query: 842 PPDCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKMIRNPASLKIVARENGGASHPLLDQ 901
P DCP++LHQLMLDCWQKDRN RP+F Q+V+ LDKMIRNP SLK +A + G + PLLD+
Sbjct: 849 PMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLSSGINLPLLDR 908
Query: 902 RQPHYSAFGSVGEWLRAIKMGRYEESFAAAGFGSFELVSQISAEDLLRIGVTLAGHQKKI 961
P Y++F +V EWL AIKMG+Y+ESFA AGF SF++VSQ+ ED+LR+GVTLAGHQKKI
Sbjct: 909 TIPDYTSFNTVDEWLEAIKMGQYKESFANAGFTSFDVVSQMMMEDILRVGVTLAGHQKKI 968
Query: 962 LASVQHMKSQ 971
L S+Q M++Q
Sbjct: 969 LNSIQVMRAQ 978
>gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens]
Length = 984
Score = 1084 bits (2803), Expect = 0.0
Identities = 555/980 (56%), Positives = 701/980 (71%), Gaps = 16/980 (1%)
Query: 1 MELRVLLCWASLAAALEETLLNTKLETADLKWVTFPQVDGQWEELSGLDEEQHSVRTYEV 60
++ +LL AS AA+EETL++T+ TA+L W P WEE+SG DE +++RTY+V
Sbjct: 3 LDYLLLLLLASAVAAMEETLMDTRTATAELGWTANPA--SGWEEVSGYDENLNTIRTYQV 60
Query: 61 CDVQRAPGQAHWLRTGWVPRRGAVHVYATLRFTMLECLSLPRAGRSCKETFTVFYYESDA 120
C+V P Q +WL T ++ RRGA +Y +RFT+ +C SLP SCKETF ++YYE+D+
Sbjct: 61 CNVFE-PNQNNWLLTTFINRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDS 119
Query: 121 DTATALTPAWMENPYIKVDTVAAEHLTRKRPGAEATGKVNVKTLRLGPLSKAGFYLAFQD 180
AT + W E PY+KVDT+AA+ + KVN + GPL++ GFYLAFQD
Sbjct: 120 VIATKKSAFWSEAPYLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQD 179
Query: 181 QGACMALLSLHLFYKKCAQLTVNLTRFPETVP---RELVVPVAGSCVVDAVPAPGPSPSL 237
GACM+LLS+ +F+KKC + N FPET+ +V G+C+ +A P L
Sbjct: 180 YGACMSLLSVRVFFKKCPSIVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVPI-KL 238
Query: 238 YCREDGQWAEQPVTGCSCAPGFEAAEGNTKCRACAQGTFKPLSGEGSCQPCPANSHSNTI 297
YC DG+W P+ C+C PG+E E + C+AC GTFK C CP+NS S
Sbjct: 239 YCNGDGEWMV-PIGRCTCKPGYEP-ENSVACKACPAGTFKASQEAEGCSHCPSNSRSPAE 296
Query: 298 GSAVCQCRVGYFRARTDPRGAPCTTPPSAPRSVVSRLNGSSLHLEWSAPLESGGREDLTY 357
S +C CR GY+RA DP CT+ PS PR+V+S +N +S+ LEW P E+GGR+D+TY
Sbjct: 297 ASPICTCRTGYYRADFDPPEVACTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTY 356
Query: 358 ALRCRECRPGG-SCAPCGGDLTFDPGPRDLVEPWVVVRGLRPDFTYTFEVTALNGVSSLA 416
+ C++CR SC+ C ++ F P L E V + L YTF++ A+NGVSS +
Sbjct: 357 NIICKKCRADRRSCSRCDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKS 416
Query: 417 TGPVPFEPVNVTTDREVPPAVSDIRVTRSSPSSLSLAWAVPRAPSGAVLDYEVKYHEKGA 476
P VN+TT++ P V + ++ S++L+W P P+G +LDYE++Y+EK
Sbjct: 417 PFPPQHVSVNITTNQAAPSTVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEH 476
Query: 477 EGPSSVRFLKTSENRAELRGLKRGASYLVQVRARSEAGYGPFGQEHHSQTQLDES--EGW 534
+S ++ N A + GL+ G Y+VQVRAR+ AGYG F + QT D+
Sbjct: 477 NEFNS-SMARSQTNTARIDGLRPGMVYVVQVRARTVAGYGKFSGKMCFQTLTDDDYKSEL 535
Query: 535 REQLALIAGTAVVGVVLVLVVIVVAVLCLRKQSNGREAEYSDKHGQYLIGHGT---KVYI 591
REQL LIAG+A GVV V+ ++ ++++C RK++ +EA YSDK Y G G+ K+YI
Sbjct: 536 REQLPLIAGSAAAGVVFVVSLVAISIVCSRKRAYSKEAVYSDKLQHYSTGRGSPGMKIYI 595
Query: 592 DPFTYEDPNEAVREFAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKG 651
DPFTYEDPNEAVREFAKEIDVS+VKIEEVIGAGEFGEV +GRLK PGK+E VAIKTLK
Sbjct: 596 DPFTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKA 655
Query: 652 GYTERQRREFLSEASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLNDGQ 711
GY+E+QRR+FLSEASIMGQF+HPNIIRLEGVVT S PVMI+TEFMENGALDSFLR NDGQ
Sbjct: 656 GYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQ 715
Query: 712 FTVIQLVGMLRGIASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSD 771
FTVIQLVGMLRGIA+GM+YLAEM+YVHRDLAARNILVNSNLVCKVSDFGLSR+L++++SD
Sbjct: 716 FTVIQLVGMLRGIAAGMKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSD 775
Query: 772 PTYTSSLGGKIPIRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVIN 831
PTYTSSLGGKIP+RWTAPEAIA+RKFTSASD WSYGIVMWEVMSFGERPYWDMSNQDVIN
Sbjct: 776 PTYTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVIN 835
Query: 832 AIEQDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKMIRNPASLKIVAREN 891
AIEQDYRLPPP DCP +LHQLMLDCWQKDRN+RPRF ++V+ LDKMIRNPASLK VA
Sbjct: 836 AIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVATIT 895
Query: 892 GGASHPLLDQRQPHYSAFGSVGEWLRAIKMGRYEESFAAAGFGSFELVSQISAEDLLRIG 951
S PLLD+ P ++AF +V +WL AIKM +Y +SF AGF S +LV+Q+++EDLLRIG
Sbjct: 896 AVPSQPLLDRSIPDFTAFTTVDDWLSAIKMVQYRDSFLTAGFTSLQLVTQMTSEDLLRIG 955
Query: 952 VTLAGHQKKILASVQHMKSQ 971
+TLAGHQKKIL S+ M+ Q
Sbjct: 956 ITLAGHQKKILNSIHSMRVQ 975
>gi|4758280 ephrin receptor EphA4 [Homo sapiens]
Length = 986
Score = 961 bits (2483), Expect = 0.0
Identities = 494/966 (51%), Positives = 659/966 (68%), Gaps = 27/966 (2%)
Query: 15 ALEETLLNTKLETADLKWVTFPQVDGQWEELSGLDEEQHSVRTYEVCDVQRAPGQAHWLR 74
A E TLL+++ +L W+ P ++G WEE+S +DE+ +RTY+VC+V P Q +WLR
Sbjct: 28 ANEVTLLDSRSVQGELGWIASP-LEGGWEEVSIMDEKNTPIRTYQVCNVME-PSQNNWLR 85
Query: 75 TGWVPRRGAVHVYATLRFTMLECLSLPRAGRSCKETFTVFYYESDADTATALTPAWMENP 134
T W+ R GA VY ++FT+ +C SLP +CKETF ++YYESD D + EN
Sbjct: 86 TDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESDNDKERFIR----ENQ 141
Query: 135 YIKVDTVAAEHLTRKRPGAEATGKVNVKTLRLGPLSKAGFYLAFQDQGACMALLSLHLFY 194
++K+DT+AA+ + + K+N + +GPLSK GFYLAFQD GAC+AL+S+ +FY
Sbjct: 142 FVKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFY 201
Query: 195 KKCAQLTVNLTRFPETVP---RELVVPVAGSCVVDAVPAPGPSPSLYCREDGQWAEQPVT 251
KKC NL +FP+T+ +V V GSCV ++ P +YC DG+W P+
Sbjct: 202 KKCPLTVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEKD--VPKMYCGADGEWLV-PIG 258
Query: 252 GCSCAPGFEAAEGNTKCRACAQGTFKPLSGEGSCQPCPANSHSNTIGSAVCQCRVGYFRA 311
C C G E G +C+AC G +K LS + +C CP +S+S G+ C C G+FRA
Sbjct: 259 NCLCNAGHEERSG--ECQACKIGYYKALSTDATCAKCPPHSYSVWEGATSCTCDRGFFRA 316
Query: 312 RTDPRGAPCTTPPSAPRSVVSRLNGSSLHLEWSAPLESGGREDLTYALRCRECRPG--GS 369
D PCT PPSAP +++S +N +S++LEWS+P +GGR+D++Y + C++C G
Sbjct: 317 DNDAASMPCTRPPSAPLNLISNVNETSVNLEWSSPQNTGGRQDISYNVVCKKCGAGDPSK 376
Query: 370 CAPCGGDLTFDPGPRDLVEPWVVVRGLRPDFTYTFEVTALNGVSSLATGPVPFEPVNVTT 429
C PCG + + P L V + L YTFE+ A+NGVS P V VTT
Sbjct: 377 CRPCGSGVHYTPQQNGLKTTKVSITDLLAHTNYTFEIWAVNGVSKYNPNPDQSVSVTVTT 436
Query: 430 DREVPPAVSDIRVTRSSPSSLSLAWAVPRAPSGAVLDYEVKYHEKGAEGPSSVRFLKTSE 489
++ P +++ ++ + S++LAW P P+G +L+YEVKY+EK + S R ++T+
Sbjct: 437 NQAAPSSIALVQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYEKD-QNERSYRIVRTAA 495
Query: 490 NRAELRGLKRGASYLVQVRARSEAGYGPFGQEHHSQTQLDES----EGWREQLALIAGTA 545
+++GL SY+ VRAR+ AGYG F + T S +G + L++
Sbjct: 496 RNTDIKGLNPLTSYVFHVRARTAAGYGDFSEPLEVTTNTVPSRIIGDGANSTVLLVS--- 552
Query: 546 VVGVVLVLVVIVVAVLCLRKQSNGREAEYSDKHGQYLIGHGTKVYIDPFTYEDPNEAVRE 605
V G V+++V+++ A + R++S +A+ ++L G + Y+DPFTYEDPN+AVRE
Sbjct: 553 VSGSVVLVVILIAAFVISRRRSKYSKAKQEADEEKHL-NQGVRTYVDPFTYEDPNQAVRE 611
Query: 606 FAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEA 665
FAKEID S +KIE+VIG GEFGEVC GRLK PGK+E CVAIKTLK GYT++QRR+FLSEA
Sbjct: 612 FAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLSEA 671
Query: 666 SIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIA 725
SIMGQF+HPNII LEGVVT PVMI+TE+MENG+LD+FLR NDG+FTVIQLVGMLRGI
Sbjct: 672 SIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIG 731
Query: 726 SGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIR 785
SGM+YL++MSYVHRDLAARNILVNSNLVCKVSDFG+SR LE++ + YT+ GGKIPIR
Sbjct: 732 SGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDD-PEAAYTTR-GGKIPIR 789
Query: 786 WTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPPDC 845
WTAPEAIA+RKFTSASD WSYGIVMWEVMS+GERPYWDMSNQDVI AIE+ YRLPPP DC
Sbjct: 790 WTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDC 849
Query: 846 PTSLHQLMLDCWQKDRNARPRFPQVVSALDKMIRNPASLKIVARENGGASHPLLDQRQPH 905
P +LHQLMLDCWQK+R+ RP+F Q+V+ LDK+IRNP SLK E+ + LLD P
Sbjct: 850 PIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGTESSRPNTALLDPSSPE 909
Query: 906 YSAFGSVGEWLRAIKMGRYEESFAAAGFGSFELVSQISAEDLLRIGVTLAGHQKKILASV 965
+SA SVG+WL+AIKM RY+++F AAG+ + E V ++ EDL RIG+T HQ KIL+SV
Sbjct: 910 FSAVVSVGDWLQAIKMDRYKDNFTAAGYTTLEAVVHVNQEDLARIGITAITHQNKILSSV 969
Query: 966 QHMKSQ 971
Q M++Q
Sbjct: 970 QAMRTQ 975
>gi|4758282 ephrin receptor EphA7 [Homo sapiens]
Length = 998
Score = 942 bits (2436), Expect = 0.0
Identities = 489/974 (50%), Positives = 647/974 (66%), Gaps = 31/974 (3%)
Query: 14 AALEETLLNTKLETADLKWVTFPQVDGQWEELSGLDEEQHSVRTYEVCDVQRAPGQAHWL 73
AA E LL++K + +L+W++ P WEE+SGLDE +RTY+VC V P Q +WL
Sbjct: 29 AAKEVLLLDSKAQQTELEWISSPP--NGWEEISGLDENYTPIRTYQVCQVME-PNQNNWL 85
Query: 74 RTGWVPRRGAVHVYATLRFTMLECLSLPRAGRSCKETFTVFYYESDADTATALTPAWMEN 133
RT W+ + A ++ L+FT+ +C SLP +CKETF ++YYE+D DT + EN
Sbjct: 86 RTNWISKGNAQRIFVELKFTLRDCNSLPGVLGTCKETFNLYYYETDYDTGRNIR----EN 141
Query: 134 PYIKVDTVAAEHLTRKRPGAEATGKVNVKTLRLGPLSKAGFYLAFQDQGACMALLSLHLF 193
Y+K+DT+AA+ + E K+N + +GPLSK GFYLAFQD GAC+AL+S+ ++
Sbjct: 142 LYVKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSKKGFYLAFQDVGACIALVSVKVY 201
Query: 194 YKKCAQLTVNLTRFPETVPRE---LVVPVAGSCVVDAVPAPGPSPSLYCREDGQWAEQPV 250
YKKC + NL FP+TV +V V G+CV A +P ++C +G+W P+
Sbjct: 202 YKKCWSIIENLAIFPDTVTGSEFSSLVEVRGTCVSSAEEEAENAPRMHCSAEGEWLV-PI 260
Query: 251 TGCSCAPGFEAAEGNTKCRACAQGTFKPLSGEGSCQPCPANSHSNTIGSAVCQCRVGYFR 310
C C G++ +G+T C C +G +K S + C CP +S S+ GS+ C+C GY+R
Sbjct: 261 GKCICKAGYQQ-KGDT-CEPCGRGFYKSSSQDLQCSRCPTHSFSDKEGSSRCECEDGYYR 318
Query: 311 ARTDPRGAPCTTPPSAPRSVVSRLNGSSLHLEWSAPLESGGREDLTYALRCRECR-PGGS 369
A +DP CT PPSAP++++ +N +++ LEWS P ++GGR D+TY + C+ C G
Sbjct: 319 APSDPPYVACTRPPSAPQNLIFNINQTTVSLEWSPPADNGGRNDVTYRILCKRCSWEQGE 378
Query: 370 CAPCGGDLTFDPGPRDLVEPWVVVRGLRPDFTYTFEVTALNGVSSLATGPVPFEPVNVTT 429
C PCG ++ + P L + +V V L YTFEV A+NGVS L+ F V++TT
Sbjct: 379 CVPCGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFAAVSITT 438
Query: 430 DREVPPAVSDIRVTRSSPSSLSLAWAVPRAPSGAVLDYEVKYHEKGAEGPSSVRFLKTSE 489
+ P VS + R S+ L+W P P+G + +YE+KY+EK + + +KT
Sbjct: 439 GQAAPSQVSGVMKERVLQRSVELSWQEPEHPNGVITEYEIKYYEKD-QRERTYSTVKTKS 497
Query: 490 NRAELRGLKRGASYLVQVRARSEAGYGPFGQEHHSQTQLDESEGW----------REQLA 539
A + LK G Y+ Q+RA + AGYG + T L+E+ G + +
Sbjct: 498 TSASINNLKPGTVYVFQIRAFTAAGYGNYSPRLDVAT-LEEATGKMFEATAVSSEQNPVI 556
Query: 540 LIAGTAVVGVVLVLVVIVVAVLCLRKQSNGREAEYSDKHGQYLIGH--GTKVYIDPFTYE 597
+IA AV G + +LV +V + R+ +A+ Y GTK YIDP TYE
Sbjct: 557 IIAVVAVAGTI-ILVFMVFGFIIGRRHCGYSKADQEGDEELYFHFKFPGTKTYIDPETYE 615
Query: 598 DPNEAVREFAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQ 657
DPN AV +FAKE+D S +KIE VIGAGEFGEVC GRLK PGK++ VAIKTLK GYTE+Q
Sbjct: 616 DPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQ 675
Query: 658 RREFLSEASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLNDGQFTVIQL 717
RR+FL EASIMGQF+HPN++ LEGVVT PVMI+ EFMENGALD+FLR +DGQFTVIQL
Sbjct: 676 RRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQL 735
Query: 718 VGMLRGIASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSS 777
VGMLRGIA+GMRYLA+M YVHRDLAARNILVNSNLVCKVSDFGLSR +E++ + YT++
Sbjct: 736 VGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDD-PEAVYTTT 794
Query: 778 LGGKIPIRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDY 837
GGKIP+RWTAPEAI +RKFTSASD WSYGIVMWEVMS+GERPYWDMSNQDVI AIE+ Y
Sbjct: 795 -GGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGY 853
Query: 838 RLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKMIRNPASLKIVARENGGASHP 897
RLP P DCP LHQLMLDCWQK+R RP+F Q+V LDKMIRNP SLK P
Sbjct: 854 RLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPNSLKTPLGTCSRPISP 913
Query: 898 LLDQRQPHYSAFGSVGEWLRAIKMGRYEESFAAAGFGSFELVSQISAEDLLRIGVTLAGH 957
LLDQ P ++ F SVGEWL+AIKM RY+++F AAG+ S E V++++ ED++ +G+TL GH
Sbjct: 914 LLDQNTPDFTTFCSVGEWLQAIKMERYKDNFTAAGYNSLESVARMTIEDVMSLGITLVGH 973
Query: 958 QKKILASVQHMKSQ 971
QKKI++S+Q M++Q
Sbjct: 974 QKKIMSSIQTMRAQ 987
>gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sapiens]
Length = 1015
Score = 925 bits (2391), Expect = 0.0
Identities = 486/985 (49%), Positives = 650/985 (65%), Gaps = 31/985 (3%)
Query: 5 VLLCWASLAAAL-----EETLLNTKLETADLKWVTFPQVDGQWEELSGLDEEQHSVRTYE 59
+LLC A+L L E LL+++ DL W+ FP+ WEE+ +DE + TY+
Sbjct: 44 LLLC-AALRTLLASPSNEVNLLDSRTVMGDLGWIAFPK--NGWEEIGEVDENYAPIHTYQ 100
Query: 60 VCDVQRAPGQAHWLRTGWVPRRGAVHVYATLRFTMLECLSLPRAGRSCKETFTVFYYESD 119
VC V Q +WL T W+ GA ++ L+FT+ +C SLP +CKETF ++Y+ESD
Sbjct: 101 VCKVMEQ-NQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESD 159
Query: 120 ADTATALTPAWMENPYIKVDTVAAEHLTRKRPGAEATGKVNVKTLRLGPLSKAGFYLAFQ 179
+ EN YIK+DT+AA+ + + K+N + +GPLSK GFYLAFQ
Sbjct: 160 DQNGRNIK----ENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQ 215
Query: 180 DQGACMALLSLHLFYKKCAQLTVNLTRFPETVP---RELVVPVAGSCVVDAVPAPGPSPS 236
D GAC+AL+S+ ++YKKC + +L FP+T+ ++ V+GSCV +V P
Sbjct: 216 DVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVT--DEPPK 273
Query: 237 LYCREDGQWAEQPVTGCSCAPGFEAAEGNTKCRACAQGTFKPLSGEGSCQPCPANSHSNT 296
++C +G+W P+ C C G+E E N C+ C G FK SC CP +S+++
Sbjct: 274 MHCSAEGEWLV-PIGKCMCKAGYE--EKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHE 330
Query: 297 IGSAVCQCRVGYFRARTDPRGAPCTTPPSAPRSVVSRLNGSSLHLEWSAPLESGGREDLT 356
S C C YFR +DP CT PPSAPR+ +S +N +S+ LEW P ++GGR+D++
Sbjct: 331 EASTSCVCEKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVS 390
Query: 357 YALRCRECRP-GGSCAPCGGDLTFDPGPRDLVEPWVVVRGLRPDFTYTFEVTALNGVSSL 415
Y + C++C G C CGG + + P L V++ L YTFE+ A+NGVS L
Sbjct: 391 YYIACKKCNSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDL 450
Query: 416 ATGPVPFEPVNVTTDREVPPAVSDIRVTRSSPSSLSLAWAVPRAPSGAVLDYEVKYHEKG 475
+ G + VNVTT++ P V++++ + + +S+SL+W P P+G +L+YE+KY EK
Sbjct: 451 SPGARQYVSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKD 510
Query: 476 AEGPSSVRFLKTSENRAELRGLKRGASYLVQVRARSEAGYGPFGQEHHSQTQ-LDESEGW 534
E +S +K+ E GLK + Y+ Q+RAR+ AGYG F + +T + +
Sbjct: 511 QE--TSYTIIKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPVFAASSD 568
Query: 535 REQLALIAGTAVVGVVLVLVVIVVAVLCLR----KQSNGREAEYSDKHGQYLIGHGTKVY 590
+ Q+ +IA + VGV+L+ VVI V + R K E E H ++ G + Y
Sbjct: 569 QSQIPVIAVSVTVGVILLAVVIGVLLSGRRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTY 628
Query: 591 IDPFTYEDPNEAVREFAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLK 650
IDP TYEDPN+AV EFAKEI+ S + IE VIGAGEFGEVC GRLK PGK+E VAIKTLK
Sbjct: 629 IDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLK 688
Query: 651 GGYTERQRREFLSEASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLNDG 710
GYTE+QRR+FL EASIMGQF+HPNII LEGVVT S PVMI+TE+MENG+LD+FL+ NDG
Sbjct: 689 VGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDG 748
Query: 711 QFTVIQLVGMLRGIASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSS 770
QFTVIQLVGMLRGI++GM+YL++M YVHRDLAARNIL+NSNLVCKVSDFGLSR LE++
Sbjct: 749 QFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDD-P 807
Query: 771 DPTYTSSLGGKIPIRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVI 830
+ YT+ GGKIPIRWTAPEAIAFRKFTSASD WSYGIVMWEV+S+GERPYW+M+NQDVI
Sbjct: 808 EAAYTTR-GGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVI 866
Query: 831 NAIEQDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKMIRNPASLKIVARE 890
A+E+ YRLP P DCP +L+QLMLDCWQK+RN+RP+F ++V+ LDK+IRNP+SLK +
Sbjct: 867 KAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNA 926
Query: 891 NGGASHPLLDQRQPHYSAFGSVGEWLRAIKMGRYEESFAAAGFGSFELVSQISAEDLLRI 950
+ S+ L + A+ SVGEWL AIKMGRY E F G+ S + V+Q++ EDL R+
Sbjct: 927 SCRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRL 986
Query: 951 GVTLAGHQKKILASVQHMKSQAKPG 975
GVTL GHQKKI+ S+Q MK Q G
Sbjct: 987 GVTLVGHQKKIMNSLQEMKVQLVNG 1011
>gi|21361241 ephrin receptor EphA3 isoform a precursor [Homo
sapiens]
Length = 983
Score = 924 bits (2387), Expect = 0.0
Identities = 479/974 (49%), Positives = 645/974 (66%), Gaps = 38/974 (3%)
Query: 17 EETLLNTKLETADLKWVTFPQVDGQWEELSGLDEEQHSVRTYEVCDVQRAPGQAHWLRTG 76
E LL++K +L W+++P WEE+SG+DE +RTY+VC+V Q +WLRT
Sbjct: 29 EVNLLDSKTIQGELGWISYPSHG--WEEISGVDEHYTPIRTYQVCNVMDH-SQNNWLRTN 85
Query: 77 WVPRRGAVHVYATLRFTMLECLSLPRAGRSCKETFTVFYYESDADTATALTPAWMENPYI 136
WVPR A +Y L+FT+ +C S+P +CKETF ++Y ESD D + E+ +
Sbjct: 86 WVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVK----FREHQFT 141
Query: 137 KVDTVAAEHLTRKRPGAEATGKVNVKTLRLGPLSKAGFYLAFQDQGACMALLSLHLFYKK 196
K+DT+AA+ + + K+N + +GP++K GFYLAFQD GAC+AL+S+ +++KK
Sbjct: 142 KIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKK 201
Query: 197 CAQLTVNLTRFPETVPREL--VVPVAGSCVVDAVPAPGPSPSLYCREDGQWAEQPVTGCS 254
C NL FP+TVP + +V V GSCV ++ P +YC +G+W P+ CS
Sbjct: 202 CPFTVKNLAMFPDTVPMDSQSLVEVRGSCVNNSKEED--PPRMYCSTEGEWLV-PIGKCS 258
Query: 255 CAPGFEAAEGNTKCRACAQGTFKPLSGEGSCQPCPANSHSNTIGSAVCQCRVGYFRARTD 314
C G+E E C+AC G +K L G C CP +S + GS C+C YFRA D
Sbjct: 259 CNAGYE--ERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKD 316
Query: 315 PRGAPCTTPPSAPRSVVSRLNGSSLHLEWSAPLESGGREDLTYALRCRECRPG-GSCAPC 373
P CT PPS+PR+V+S +N +S+ L+WS PL++GGR+D+T+ + C++C C PC
Sbjct: 317 PPSMACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPC 376
Query: 374 GGDLTFDPGPRDLVEPWVVVRGLRPDFTYTFEVTALNGVSSLATGPVPFEPVNVTTDREV 433
++ F P L V V L YTFE+ A+NGVS L++ P F V++TT++
Sbjct: 377 SPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAA 436
Query: 434 PPAVSDIRVTRSSPSSLSLAWAVPRAPSGAVLDYEVKYHEKGAEGPSSVRFLKTSENRAE 493
P V I+ R+S +S+SL+W P P+G +LDYEVKY+EK E +S L+
Sbjct: 437 PSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEK-QEQETSYTILRARGTNVT 495
Query: 494 LRGLKRGASYLVQVRARSEAGYGPFGQEHHSQTQLDESE--GWREQLALIAGTAVVGVVL 551
+ LK Y+ Q+RAR+ AGYG ++ +T D G Q+ +IA +A V ++L
Sbjct: 496 ISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDSFSISGESSQVVMIAISAAVAIIL 555
Query: 552 VLVVIVVAVLCLRKQSNGREAEYSDKHG------QYLIGH----GTKVYIDPFTYEDPNE 601
+ VVI V + GR Y KHG + GH G + Y+DP TYEDP +
Sbjct: 556 LTVVIYVLI--------GRFCGYKSKHGADEKRLHFGNGHLKLPGLRTYVDPHTYEDPTQ 607
Query: 602 AVREFAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREF 661
AV EFAKE+D + + I++V+GAGEFGEVC GRLK P KKE VAIKTLK GYTE+QRR+F
Sbjct: 608 AVHEFAKELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRRDF 667
Query: 662 LSEASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLNDGQFTVIQLVGML 721
L EASIMGQF+HPNIIRLEGVVT S PVMI+TE+MENG+LDSFLR +D QFTVIQLVGML
Sbjct: 668 LGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTVIQLVGML 727
Query: 722 RGIASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGK 781
RGIASGM+YL++M YVHRDLAARNIL+NSNLVCKVSDFGLSR LE++ + YT+ GGK
Sbjct: 728 RGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDD-PEAAYTTR-GGK 785
Query: 782 IPIRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPP 841
IPIRWT+PEAIA+RKFTSASD WSYGIV+WEVMS+GERPYW+MSNQDVI A+++ YRLPP
Sbjct: 786 IPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRLPP 845
Query: 842 PPDCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKMIRNPASLKIVARENGGASHPLLDQ 901
P DCP +L+QLMLDCWQKDRN RP+F Q+VS LDK+IRNP SLKI+ S+ LLDQ
Sbjct: 846 PMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKIITSAAARPSNLLLDQ 905
Query: 902 RQPHYSAFGSVGEWLRAIKMGRYEESFAAAGFGSFELVSQISAEDLLRIGVTLAGHQKKI 961
+ F + G+WL + +E F + S + +++IS +D+ ++GVT+ G QKKI
Sbjct: 906 SNVDITTFRTTGDWLNGVWTAHCKEIFTGVEYSSCDTIAKISTDDMKKVGVTVVGPQKKI 965
Query: 962 LASVQHMKSQAKPG 975
++S++ +++Q+K G
Sbjct: 966 ISSIKALETQSKNG 979
>gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sapiens]
Length = 1037
Score = 917 bits (2371), Expect = 0.0
Identities = 487/1007 (48%), Positives = 651/1007 (64%), Gaps = 53/1007 (5%)
Query: 5 VLLCWASLAAAL-----EETLLNTKLETADLKWVTFPQVDGQWEELSGLDEEQHSVRTYE 59
+LLC A+L L E LL+++ DL W+ FP+ WEE+ +DE + TY+
Sbjct: 44 LLLC-AALRTLLASPSNEVNLLDSRTVMGDLGWIAFPK--NGWEEIGEVDENYAPIHTYQ 100
Query: 60 VCDVQRAPGQAHWLRTGWVPRRGAVHVYATLRFTMLECLSLPRAGRSCKETFTVFYYESD 119
VC V Q +WL T W+ GA ++ L+FT+ +C SLP +CKETF ++Y+ESD
Sbjct: 101 VCKVMEQ-NQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESD 159
Query: 120 ADTATALTPAWMENPYIKVDTVAAEHLTRKRPGAEATGKVNVKTLRLGPLSKAGFYLAFQ 179
+ EN YIK+DT+AA+ + + K+N + +GPLSK GFYLAFQ
Sbjct: 160 DQNGRNIK----ENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQ 215
Query: 180 DQGACMALLSLHLFYKKCAQLTVNLTRFPETVP---RELVVPVAGSCVVDAVPAPGPSPS 236
D GAC+AL+S+ ++YKKC + +L FP+T+ ++ V+GSCV +V P
Sbjct: 216 DVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVT--DEPPK 273
Query: 237 LYCREDGQWAEQPVTGCSCAPGFEAAEGNTKCRACAQGTFKPLSGEGSCQPCPANSHSNT 296
++C +G+W P+ C C G+E E N C+ C G FK SC CP +S+++
Sbjct: 274 MHCSAEGEWLV-PIGKCMCKAGYE--EKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHE 330
Query: 297 IGSAVCQCRVGYFRARTDPRGAPCTTPPSAPRSVVSRLNGSSLHLEWSAPLESGGREDLT 356
S C C YFR +DP CT PPSAPR+ +S +N +S+ LEW P ++GGR+D++
Sbjct: 331 EASTSCVCEKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVS 390
Query: 357 YALRCRECRP-GGSCAPCGGDLTFDPGPRDLVEPWVVVRGLRPDFTYTFEVTALNGVSSL 415
Y + C++C G C CGG + + P L V++ L YTFE+ A+NGVS L
Sbjct: 391 YYIACKKCNSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDL 450
Query: 416 ATGPVPFEPVNVTTDREVPPAVSDIRVTRSSPSSLSLAWAVPRAPSGAVLDYEVKYHEKG 475
+ G + VNVTT++ P V++++ + + +S+SL+W P P+G +L+YE+KY EK
Sbjct: 451 SPGARQYVSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKD 510
Query: 476 AEGPSSVRFLKTSENRAELRGLKRGASYLVQVRARSEAGYGPFGQEHHSQTQ-LDESEGW 534
E +S +K+ E GLK + Y+ Q+RAR+ AGYG F + +T + +
Sbjct: 511 QE--TSYTIIKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPVFAASSD 568
Query: 535 REQLALIAGTAVVGVVLVLVVIVVAV--------------LCL------------RKQSN 568
+ Q+ +IA + VGV+L+ VVI V + LC K
Sbjct: 569 QSQIPVIAVSVTVGVILLAVVIGVLLSGSCCECGCGRASSLCAVAHPSLIWRCGYSKAKQ 628
Query: 569 GREAEYSDKHGQYLIGHGTKVYIDPFTYEDPNEAVREFAKEIDVSYVKIEEVIGAGEFGE 628
E E H ++ G + YIDP TYEDPN+AV EFAKEI+ S + IE VIGAGEFGE
Sbjct: 629 DPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGE 688
Query: 629 VCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRLEGVVTNSMP 688
VC GRLK PGK+E VAIKTLK GYTE+QRR+FL EASIMGQF+HPNII LEGVVT S P
Sbjct: 689 VCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKP 748
Query: 689 VMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIASGMRYLAEMSYVHRDLAARNILV 748
VMI+TE+MENG+LD+FL+ NDGQFTVIQLVGMLRGI++GM+YL++M YVHRDLAARNIL+
Sbjct: 749 VMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILI 808
Query: 749 NSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRWTAPEAIAFRKFTSASDAWSYGI 808
NSNLVCKVSDFGLSR LE++ + YT+ GGKIPIRWTAPEAIAFRKFTSASD WSYGI
Sbjct: 809 NSNLVCKVSDFGLSRVLEDD-PEAAYTTR-GGKIPIRWTAPEAIAFRKFTSASDVWSYGI 866
Query: 809 VMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFP 868
VMWEV+S+GERPYW+M+NQDVI A+E+ YRLP P DCP +L+QLMLDCWQK+RN+RP+F
Sbjct: 867 VMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFD 926
Query: 869 QVVSALDKMIRNPASLKIVARENGGASHPLLDQRQPHYSAFGSVGEWLRAIKMGRYEESF 928
++V+ LDK+IRNP+SLK + + S+ L + A+ SVGEWL AIKMGRY E F
Sbjct: 927 EIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGRYTEIF 986
Query: 929 AAAGFGSFELVSQISAEDLLRIGVTLAGHQKKILASVQHMKSQAKPG 975
G+ S + V+Q++ EDL R+GVTL GHQKKI+ S+Q MK Q G
Sbjct: 987 MENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQLVNG 1033
>gi|145312251 EPH receptor A6 isoform a [Homo sapiens]
Length = 1130
Score = 896 bits (2315), Expect = 0.0
Identities = 484/1009 (47%), Positives = 640/1009 (63%), Gaps = 81/1009 (8%)
Query: 20 LLNTKLETADLKWVTFPQVDGQWEELSGLDEEQHSVRTYEVCDVQRAPGQAHWLRTGWVP 79
LL+T +L W T+P ++G W+ ++ +DE + TY+VC+V P Q +WLRT W+
Sbjct: 131 LLDTTTVLGELGWKTYP-LNG-WDAITEMDEHNRPIHTYQVCNVME-PNQNNWLRTNWIS 187
Query: 80 RRGAVHVYATLRFTMLECLSLPRAGRSCKETFTVFYYESDADTATALTPAWMENPYIKVD 139
R A +Y ++FT+ +C S+P +CKETF +FY ESD P N Y K+D
Sbjct: 188 RDAAQKIYVEMKFTLRDCNSIPWVLGTCKETFNLFYMESDESHGIKFKP----NQYTKID 243
Query: 140 TVAAEHLTRKRPGAEATGKVNVKTLRLGPLSKAGFYLAFQDQGACMALLSLHLFYKKCAQ 199
T+AA+ + + K+N + +GP+ + GFYLAFQD GAC+AL+S+ +FYKKC
Sbjct: 244 TIAADESFTQMDLGDRILKLNTEIREVGPIERKGFYLAFQDIGACIALVSVRVFYKKCPF 303
Query: 200 LTVNLTRFPETVPR---ELVVPVAGSCVVDAVPAPGPSPSLYCREDGQWAEQPVTGCSCA 256
NL FP+T+PR +V V GSCV A +P LYC DG W P+ C C+
Sbjct: 304 TVRNLAMFPDTIPRVDSSSLVEVRGSCVKSAEERD--TPKLYCGADGDWLV-PLGRCICS 360
Query: 257 PGFEAAEGNTKCRACAQGTFKPLSGEGSCQPCPANSHSNTIGSAVCQCRVGYFRARTDPR 316
G+E EG+ C AC G +K +G C CP +S + ++VCQC GYFRA DP
Sbjct: 361 TGYEEIEGS--CHACRPGFYKAFAGNTKCSKCPPHSLTYMEATSVCQCEKGYFRAEKDPP 418
Query: 317 GAPCTTPPSAPRSVVSRLNGSSLHLEWSAPLESGGREDLTYALRCRECRPGGS-CAPCGG 375
CT PPSAPR+VV +N ++L LEWS P ++GGR+DLTY++ C++C S C CGG
Sbjct: 419 SMACTRPPSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSVICKKCGLDTSQCEDCGG 478
Query: 376 DLTFDPGPRDLVEPWVVVRGLRPDFTYTFEVTALNGVSSLATGPVPFEPVNVTTDREVPP 435
L F P L+ V+V YTFE+ A+NGVS L+ P PF + VTTD++ P
Sbjct: 479 GLRFIPRHTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSFSPKPFTAITVTTDQDAPS 538
Query: 436 AVSDIRVTRSSPSSLSLAWAVPRAPSGAVLDYEVKYHEKGAEGPSSVRFLKTSENRAE-- 493
+ +R +S +S++L+W P +GA+LDYE+KY+EK E L S R++
Sbjct: 539 LIGVVRKDWASQNSIALSWQAPAFSNGAILDYEIKYYEKEHEQ------LTYSSTRSKAP 592
Query: 494 ---LRGLKRGASYLVQVRARSEAGYGPFGQEHHSQTQLDESEGWREQ-LALIAGTAVVGV 549
+ GLK Y+ +R R+ GY + Q+ +T + S+ EQ L+ TA VG
Sbjct: 593 SVIITGLKPATKYVFHIRVRTATGYSGYSQKFEFETGDETSDMAAEQGQILVIATAAVGG 652
Query: 550 VLVLVVIVVAVLC-------LRKQSNGREAEYSDKHGQYLIGHGTKVYIDPFTYEDPNEA 602
+LV++ + L ++ + E + +L G K YIDP TYEDP+ A
Sbjct: 653 FTLLVILTLFFLITGRCQWYIKAKMKSEEKRRNHLQNGHLRFPGIKTYIDPDTYEDPSLA 712
Query: 603 VREFAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFL 662
V EFAKEID S ++IE VIGAGEFGEVC GRLK PGK+E VAIKTLKGG+ +RQRR+FL
Sbjct: 713 VHEFAKEIDPSRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRDFL 772
Query: 663 SEASIMGQFEHPNIIRLEGVVT----------------------NSM------------- 687
EASIMGQF+HPNIIRLEGVVT NS+
Sbjct: 773 REASIMGQFDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLP 832
Query: 688 -------PVMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIASGMRYLAEMSYVHRD 740
PVMI+ E+MENG+LDSFLR +DG FTVIQLVGMLRGIASGM+YL++M YVHRD
Sbjct: 833 PRIPAGRPVMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHRD 892
Query: 741 LAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRWTAPEAIAFRKFTSA 800
LAARNILVNSNLVCKVSDFGLSR LE++ + YT++ GGKIPIRWTAPEAIA+RKF+SA
Sbjct: 893 LAARNILVNSNLVCKVSDFGLSRVLEDD-PEAAYTTT-GGKIPIRWTAPEAIAYRKFSSA 950
Query: 801 SDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPPDCPTSLHQLMLDCWQKD 860
SDAWSYGIVMWEVMS+GERPYW+MSNQDVI +IE+ YRLP P CP SLHQLML CWQK+
Sbjct: 951 SDAWSYGIVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKE 1010
Query: 861 RNARPRFPQVVSALDKMIRNPASLKIVARENGGASHPLLDQRQPHYSAFGSVGEWLRAIK 920
RN RP+F +VS LDK+IRNP++L + + P P Y F +VG+WL +IK
Sbjct: 1011 RNHRPKFTDIVSFLDKLIRNPSALHTLVEDI--LVMPESPGEVPEYPLFVTVGDWLDSIK 1068
Query: 921 MGRYEESFAAAGFGSFELVSQISAEDLLRIGVTLAGHQKKILASVQHMK 969
MG+Y+ +F AAGF +F+L+S++S +D+ RIGV L GHQ++I++S+Q ++
Sbjct: 1069 MGQYKNNFVAAGFTTFDLISRMSIDDIRRIGVILIGHQRRIVSSIQTLR 1117
>gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo
sapiens]
Length = 1005
Score = 850 bits (2197), Expect = 0.0
Identities = 457/988 (46%), Positives = 624/988 (63%), Gaps = 49/988 (4%)
Query: 13 AAALEETLLNTKLETADLKWVTFPQVDGQWEELSGLDEEQHSVRTYEVCDVQRAPGQAHW 72
AA E LL+T D W+T+P W+ ++ +DE + TY+VC+V +P Q +W
Sbjct: 27 AARGEVNLLDTSTIHGDWGWLTYPAHG--WDSINEVDESFQPIHTYQVCNVM-SPNQNNW 83
Query: 73 LRTGWVPRRGAVHVYATLRFTMLECLSLPRAGRSCKETFTVFYYESDADTATALTPAWME 132
LRT WVPR GA VYA ++FT+ +C S+P +CKETF ++Y ESD D L + E
Sbjct: 84 LRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESDRD----LGASTQE 139
Query: 133 NPYIKVDTVAAEHLTRKRPGAEATGKVNVKTLRLGPLSKAGFYLAFQDQGACMALLSLHL 192
+ ++K+DT+AA+ K+N + +GPLSK GFYLAFQD GAC+A+LSL +
Sbjct: 140 SQFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRI 199
Query: 193 FYKKCAQLTVNLTRFPETVP---RELVVPVAGSCVVDAVPAPGPSPSLYCREDGQWAEQP 249
+YKKC + NL F E V +V V G CV + +P +YC +G+W P
Sbjct: 200 YYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEERD--TPKMYCSAEGEWLV-P 256
Query: 250 VTGCSCAPGFEAAEGNTKCRACAQGTFKPLSGEGSCQPCPANSHSNTIGSAVCQCRVGYF 309
+ C C+ G+E E C AC G +K G+ C CP +SHS + C C + Y+
Sbjct: 257 IGKCVCSAGYE--ERRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYY 314
Query: 310 RARTDPRGAPCTTPPSAPRSVVSRLNGSSLHLEWSAPLESGGREDLTYALRCRECRPGGS 369
RA DP + CT PPSAP +++S +NG+S+ LEW+ PL+ GGR D+TY CR C S
Sbjct: 315 RAALDPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCPWALS 374
Query: 370 -CAPCGGDLTFDPGPRDLVEPWVVVRGLRPDFTYTFEVTALNGVSSLATGPVPFEPVNVT 428
C CG F P LV+ ++V L Y+F + A+NGVS L+ P VN+T
Sbjct: 375 RCEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAVVNIT 434
Query: 429 TDREVPPAVSDIRVTRSSPSSLSLAWAVPRAPSGAVLDYEVKYHEKGAEGPSSVRFLKTS 488
T++ P V IR R+ +S+SL W P P+G +L+YE+KY+EK E S LK
Sbjct: 435 TNQAAPSQVVVIRQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEKDKE-MQSYSTLKAV 493
Query: 489 ENRAELRGLKRGASYLVQVRARSEAGYGPFGQEHHSQTQLDESEGWREQLALIAGTAVVG 548
RA + GLK G Y+ QVRAR+ AG G F Q +T + I T + G
Sbjct: 494 TTRATVSGLKPGTRYVFQVRARTSAGCGRFSQAMEVETGKPRPRYDTRTIVWICLTLITG 553
Query: 549 VVLVLVVIVVAVLCLRKQSNGREAEYSD--------KHGQ-----YLIGHGT-------K 588
+V++L++++ +K+ G + D ++GQ +L H +
Sbjct: 554 LVVLLLLLIC-----KKRHCGYSKAFQDSDEEKMHYQNGQAPPPVFLPLHHPPGKLPEPQ 608
Query: 589 VYIDPFTYEDPNEAVREFAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKT 648
Y +P TYE+P A R F +EI+ S + IE++IG+G+ GEVC GRL+ PG+++ VAIK
Sbjct: 609 FYAEPHTYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAIKA 668
Query: 649 LKGGYTERQRREFLSEASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLN 708
LK GYTERQRR+FLSEASIMGQF+HPNIIRLEGVVT MI+TE+MENG+LD+FLR +
Sbjct: 669 LKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLRTH 728
Query: 709 DGQFTVIQLVGMLRGIASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEEN 768
DGQFT++QLVGMLRG+ +GMRYL+++ YVHRDLAARN+LV+SNLVCKVSDFGLSR LE++
Sbjct: 729 DGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDD 788
Query: 769 SSDPTYTSSLGGKIPIRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQD 828
D YT++ GGKIPIRWTAPEAIAFR F+SASD WS+G+VMWEV+++GERPYW+M+N+D
Sbjct: 789 -PDAAYTTT-GGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRD 846
Query: 829 VINAIEQDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKMIRNPASLKIVA 888
VI+++E+ YRLP P CP +LHQLMLDCW KDR RPRF Q+VS LD +IR+P SL+ A
Sbjct: 847 VISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPESLRATA 906
Query: 889 REN----GGASHPLLDQRQPHYSAFG-SVGEWLRAIKMGRYEESFAAAGFGSFELVSQIS 943
+ D R G +VG+WL +I+MGRY + FAA G+ S +V +++
Sbjct: 907 TVSRCPPPAFVRSCFDLRGGSGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLRMN 966
Query: 944 AEDLLRIGVTLAGHQKKILASVQHMKSQ 971
A+D+ +G+TL GHQKKIL S+Q M++Q
Sbjct: 967 AQDVRALGITLMGHQKKILGSIQTMRAQ 994
>gi|32967311 ephrin receptor EphA2 [Homo sapiens]
Length = 976
Score = 814 bits (2102), Expect = 0.0
Identities = 457/976 (46%), Positives = 602/976 (61%), Gaps = 36/976 (3%)
Query: 7 LCWASLAAALEETLLNTKLETADLKWVTFPQVDGQWEELSGLDEEQHSVRTYEVCDVQRA 66
L A+ A E LL+ +L W+T P G W+ + + + + Y VC+V
Sbjct: 18 LAAAAAAQGKEVVLLDFAAAGGELGWLTHPYGKG-WDLMQNIMNDM-PIYMYSVCNVMSG 75
Query: 67 PGQAHWLRTGWVPRRGAVHVYATLRFTMLECLSLPRAGRSCKETFTVFYYESDADTATAL 126
Q +WLRT WV R A ++ L+FT+ +C S P SCKETF ++Y ESD D T
Sbjct: 76 D-QDNWLRTNWVYRGEAERIFIELKFTVRDCNSFPGGASSCKETFNLYYAESDLDYGTN- 133
Query: 127 TPAWMENPYIKVDTVAAEHLTRKRPGAEATGKVNVKTLRLGPLSKAGFYLAFQDQGACMA 186
+ + + K+DT+A + +T K+NV+ +GPL++ GFYLAFQD GAC+A
Sbjct: 134 ---FQKRLFTKIDTIAPDEITVSSDFEARHVKLNVEERSVGPLTRKGFYLAFQDIGACVA 190
Query: 187 LLSLHLFYKKCAQLTVNLTRFPETVPRE---LVVPVAGSCVVDAVPAPG-PSPSLYCRED 242
LLS+ ++YKKC +L L FPET+ + VAG+CV AV PG P ++C D
Sbjct: 191 LLSVRVYYKKCPELLQGLAHFPETIAGSDAPSLATVAGTCVDHAVVPPGGEEPRMHCAVD 250
Query: 243 GQWAEQPVTGCSCAPGFEAAEGNTKCRACAQGTFKPLSGEGSCQPCPANSHSNTIGSAVC 302
G+W P+ C C G+E E C+AC+ G FK + E C CP ++ + G+ C
Sbjct: 251 GEWLV-PIGQCLCQAGYEKVED--ACQACSPGFFKFEASESPCLECPEHTLPSPEGATSC 307
Query: 303 QCRVGYFRARTDPRGAPCTTPPSAPRSVVSRLNGSSLHLEWSAPLESGGREDLTYALRCR 362
+C G+FRA DP PCT PPSAP + + G+ + L W+ P +SGGRED+ Y++ C
Sbjct: 308 ECEEGFFRAPQDPASMPCTRPPSAPHYLTAVGMGAKVELRWTPPQDSGGREDIVYSVTCE 367
Query: 363 ECRP-GGSCAPCGGDLTFDPGPRDLVEPWVVVRGLRPDFTYTFEVTALNGVSSLATGPVP 421
+C P G C PC + + P L V V L P YTF V A NGVS L T
Sbjct: 368 QCWPESGECGPCEASVRYSEPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSGLVTSR-S 426
Query: 422 FEPVNVTTDREVPPAVSDIRVTRSSPSSLSLAWAVPRAPSGAVLDYEVKYHEKGAEGPSS 481
F +V+ ++ PP V R+ S +SLS++W++P V YEV Y +KG +
Sbjct: 427 FRTASVSINQTEPPKV---RLEGRSTTSLSVSWSIPPPQQSRVWKYEVTYRKKGDSNSYN 483
Query: 482 VRFLKTSENRAELRGLKRGASYLVQVRARSEAGYGPFGQEHHSQTQLDESEGWREQLALI 541
VR +T L L +YLVQV+A ++ G G + H QT E G LA+I
Sbjct: 484 VR--RTEGFSVTLDDLAPDTTYLVQVQALTQEGQGAGSKVHEFQTLSPEGSG---NLAVI 538
Query: 542 AGTAVVGVVLVLVVIVVAVLCLRKQSNGR-----EAEYSDKHGQYLIGHGTKVYIDPFTY 596
G AV GVVL+LV+ V R++ N R E Y K Q K Y+DP TY
Sbjct: 539 GGVAV-GVVLLLVLAGVGFFIHRRRKNQRARQSPEDVYFSKSEQL---KPLKTYVDPHTY 594
Query: 597 EDPNEAVREFAKEIDVSYVKIEEVIGAGEFGEVCRGRLK-APGKKESCVAIKTLKGGYTE 655
EDPN+AV +F EI S V ++VIGAGEFGEV +G LK + GKKE VAIKTLK GYTE
Sbjct: 595 EDPNQAVLKFTTEIHPSCVTRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAGYTE 654
Query: 656 RQRREFLSEASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLNDGQFTVI 715
+QR +FL EA IMGQF H NIIRLEGV++ P+MI+TE+MENGALD FLR DG+F+V+
Sbjct: 655 KQRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGEFSVL 714
Query: 716 QLVGMLRGIASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYT 775
QLVGMLRGIA+GM+YLA M+YVHRDLAARNILVNSNLVCKVSDFGLSR LE++ + TYT
Sbjct: 715 QLVGMLRGIAAGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDD-PEATYT 773
Query: 776 SSLGGKIPIRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQ 835
+S GGKIPIRWTAPEAI++RKFTSASD WS+GIVMWEVM++GERPYW++SN +V+ AI
Sbjct: 774 TS-GGKIPIRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAIND 832
Query: 836 DYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKMIRNPASLKIVARENGGAS 895
+RLP P DCP++++QLM+ CWQ++R RP+F +VS LDK+IR P SLK +A + S
Sbjct: 833 GFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIRAPDSLKTLADFDPRVS 892
Query: 896 HPLLDQRQPHYSAFGSVGEWLRAIKMGRYEESFAAAGFGSFELVSQISAEDLLRIGVTLA 955
L F +V EWL +IKM +Y E F AAG+ + E V Q++ +D+ RIGV L
Sbjct: 893 IRLPSTSGSEGVPFRTVSEWLESIKMQQYTEHFMAAGYTAIEKVVQMTNDDIKRIGVRLP 952
Query: 956 GHQKKILASVQHMKSQ 971
GHQK+I S+ +K Q
Sbjct: 953 GHQKRIAYSLLGLKDQ 968
>gi|194097332 ephrin receptor EphB6 precursor [Homo sapiens]
Length = 1021
Score = 784 bits (2025), Expect = 0.0
Identities = 432/1014 (42%), Positives = 607/1014 (59%), Gaps = 67/1014 (6%)
Query: 6 LLCWASLAAALEETLLNTKLETADLKWVTFPQVDGQWEELSGLDEEQHSVRTYEVCDVQR 65
+L S ALEE LL+T ET+++ W+T+P G W+E+S LD+++ RT+E C V
Sbjct: 22 VLLLVSSVLALEEVLLDTTGETSEIGWLTYPP--GGWDEVSVLDDQRRLTRTFEACHVAG 79
Query: 66 AP---GQAHWLRTGWVPRRGAVHVYATLRFTMLECLSLPRAGRSCKETFTVFYYESDADT 122
AP GQ +WL+T +V RRGA + L F++ C SL +G +C+ETFT++Y +++
Sbjct: 80 APPGTGQDNWLQTHFVERRGAQRAHIRLHFSVRACSSLGVSGGTCRETFTLYYRQAEEPD 139
Query: 123 ATALTPAWMENPYIKVDTVAAEHL--------TRKRPGAEATG----------KVNVKTL 164
+ +W + KVDT+AA+ + A A G ++NVK
Sbjct: 140 SPDSVSSWHLKRWTKVDTIAADESFPSSSSSSSSSSSAAWAVGPHGAGQRAGLQLNVKER 199
Query: 165 RLGPLSKAGFYLAFQDQGACMALLSLHLFYKKCAQLTVNLTRFPETVPREL----VVPVA 220
GPL++ GFY+AFQD GAC+AL+++ LF C + + FPET +V
Sbjct: 200 SFGPLTQRGFYVAFQDTGACLALVAVRLFSYTCPAVLRSFASFPETQASGAGGASLVAAV 259
Query: 221 GSCVVDAVP--------APGPSPSLYCREDGQWAEQPVTGCSCAPGFEAAEGNTKCRACA 272
G+CV A P A G P L+C +G+W V GC C PG++ A G+ C+AC
Sbjct: 260 GTCVAHAEPEEDGVGGQAGGSPPRLHCNGEGKWMVA-VGGCRCQPGYQPARGDKACQACP 318
Query: 273 QGTFKPLSGEGSCQPCPANSHSNTIGSAVCQCRVGYFRARTDPRGAPCTTPPSAPRSVVS 332
+G +K +G C PCPA SH+ + VC C G++RA +DP APCT PPSAP+ +
Sbjct: 319 RGLYKSSAGNAPCSPCPARSHAPNPAAPVCPCLEGFYRASSDPPEAPCTGPPSAPQELWF 378
Query: 333 RLNGSSLHLEWSAPLESGGREDLTYALRCRECRP--------GGSCAPCGGDLTFDPGPR 384
+ GS+L L W P E GGR DL + + C+EC GG+C C ++ FDP R
Sbjct: 379 EVQGSALMLHWRLPRELGGRGDLLFNVVCKECEGRQEPASGGGGTCHRCRDEVHFDPRQR 438
Query: 385 DLVEPWVVVRGLRPDFTYTFEVTALNGVSSLATGPVPFEPVNVTTDREVPPAVSDIRVTR 444
L E V+V GLR Y EV A+NGVS L+ P +NV+T EVP AV +
Sbjct: 439 GLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAAINVSTSHEVPSAVPVVHQVS 498
Query: 445 SSPSSLSLAWAVPRAPSGAVLDYEVKYHEKGAEGPSSVRFLKTSENRAELRGLKRGASYL 504
+ +S++++W P +G +LDY+++Y+++ AE S L + N A + L G Y
Sbjct: 499 RASNSITVSWPQPDQTNGNILDYQLRYYDQ-AEDESHSFTLTSETNTATVTQLSPGHIYG 557
Query: 505 VQVRARSEAGYGPFGQEHHSQT--QLDESEGWREQLALIAGTAVVGVVLVLVVIVVAVLC 562
QVRAR+ AG+GP+G + + QT Q + S E+L+L+ G+ ++G + L++ + VL
Sbjct: 558 FQVRARTAAGHGPYGGKVYFQTLPQGELSSQLPERLSLVIGS-ILGALAFLLLAAITVLA 616
Query: 563 LRKQSNGREAEYSDKHGQYLI-GHGTKVYIDPFTYEDPNEAVREFAKEIDVSYVKIEEVI 621
+ Q R Y+++ QY G G K YIDP TYEDP +A+RE A+E+D +Y+KIEEVI
Sbjct: 617 VVFQRKRRGTGYTEQLQQYSSPGLGVKYYIDPSTYEDPCQAIRELAREVDPAYIKIEEVI 676
Query: 622 GAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRLEG 681
G G FGEV +GRL+ G++E VAI+ L G E + FL A+++GQF+HPNI+RLEG
Sbjct: 677 GTGSFGEVRQGRLQPRGRREQTVAIQALWAGGAESLQMTFLGRAAVLGQFQHPNILRLEG 736
Query: 682 VVTNSMPVMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIASGMRYLAEMSYVHRDL 741
VVT S P+M+LTEFME G LDSFLR +GQF+ +QLV M RG+A+ M+YL+ ++VHR L
Sbjct: 737 VVTKSRPLMVLTEFMELGPLDSFLRQREGQFSSLQLVAMQRGVAAAMQYLSSFAFVHRSL 796
Query: 742 AARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRWTAPEAIAFRKFTSAS 801
+A ++LVNS+LVCKV+ G S G +RW APE IA K T++S
Sbjct: 797 SAHSVLVNSHLVCKVARLG--------------HSPQGPSCLLRWAAPEVIAHGKHTTSS 842
Query: 802 DAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPPDCPTSLHQLMLDCWQKDR 861
D WS+GI+MWEVMS+GERPYWDMS Q+V+NAIEQ++RLPPPP CP LH LMLD WQKDR
Sbjct: 843 DVWSFGILMWEVMSYGERPYWDMSEQEVLNAIEQEFRLPPPPGCPPGLHLLMLDTWQKDR 902
Query: 862 NARPRFPQVVSALDKMIRNPASLKIVARENGGASHPLLDQRQPHYSAFGSVGEWLRAIKM 921
RP F Q+V+A DKMIR P +L+ S LL + S WL AI +
Sbjct: 903 ARRPHFDQLVAAFDKMIRKPDTLQAGGDPGERPSQALLTPVALDFPCLDSPQAWLSAIGL 962
Query: 922 GRYEESFAAAGFGSFELVSQISAEDLLRIGVTLAGHQKKILASV----QHMKSQ 971
Y+++F+ G +F V+Q+S EDL +G+TLAGHQKK+L + QH++ Q
Sbjct: 963 ECYQDNFSKFGLCTFSDVAQLSLEDLPALGITLAGHQKKLLHHIQLLQQHLRQQ 1016
>gi|150456460 EPH receptor A10 isofom 3 [Homo sapiens]
Length = 1008
Score = 731 bits (1887), Expect = 0.0
Identities = 410/1003 (40%), Positives = 576/1003 (57%), Gaps = 49/1003 (4%)
Query: 3 LRVLLCWASLAAAL-----------EETLLNTKLETADLKWVTFPQVDGQWEELSGLDEE 51
LR+ LC L AL E LL++K A+L W P WEE+SG+DE
Sbjct: 10 LRLFLCRMQLCLALLLGPWRPGTAEEVILLDSKASQAELGWTALPS--NGWEEISGVDEH 67
Query: 52 QHSVRTYEVCDVQRAPGQAHWLRTGWVPRRGAVHVYATLRFTMLECLSLPRAGRSCKETF 111
+RTY+VC+V P Q +WL+TGW+ R ++ L+FT+ +C S+P A +CKETF
Sbjct: 68 DRPIRTYQVCNVLE-PNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAGTCKETF 126
Query: 112 TVFYYESDADTATALTPAWMENPYIKVDTVAAEHLTRKRPGAEATGKVNVKTLRLGPLSK 171
V+Y E++AD P K+DT+AA+ + E K+N + +GPLS+
Sbjct: 127 NVYYLETEADLGRGRPRLGGSRPR-KIDTIAADESFTQGDLGERKMKLNTEVREIGPLSR 185
Query: 172 AGFYLAFQDQGACMALLSLHLFYKKCAQLTVNLTRFPETVPREL---VVPVAGSCVVDAV 228
GF+LAFQD GAC+AL+S+ ++YK+C L FP T +V VAG+CV +
Sbjct: 186 RGFHLAFQDVGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTCVAHSE 245
Query: 229 PAPGPSPSLYCREDGQWAEQPVTGCSCAPGFEAAEGNTKCRACAQGTFKPLSGEGSCQPC 288
PG P ++C DG+W PV CSC+ GF+ E C AC G +K C PC
Sbjct: 246 GEPGSPPRMHCGADGEWLV-PVGRCSCSAGFQ--ERGDFCEACPPGFYKVSPRRPLCSPC 302
Query: 289 PANSHSNTIGSAVCQCRVGYFRARTDPRGAPCTTPPSAPRSVVSRLNGSSL--HLEWSAP 346
P +S + S C C+ Y R+ TDP A CT PPSAPR + L+ S L L W P
Sbjct: 303 PEHSRALENASTFCVCQDSYARSPTDPPSASCTRPPSAPRDLQYSLSRSPLVLRLRWLPP 362
Query: 347 LESGGREDLTYALRCRECR---PGGSCAPCGGDLTFDPGPRDLVEPWVVVRGLRPDFTYT 403
+SGGR D+TY+L C C P G+C PCG + F P L E + LRP YT
Sbjct: 363 ADSGGRSDVTYSLLCLRCGREGPAGACEPCGPRVAFLPRQAGLRERAATLLHLRPGARYT 422
Query: 404 FEVTALNGVSS-LATGPVPFEPVNVTTDREVPPAVSDIRVTRSSPSSLSLAWAVP---RA 459
V ALNGVS A + V V+T P +IR R P S+SL+W P A
Sbjct: 423 VRVAALNGVSGPAAAAGTTYAQVTVSTGPGAPWEEDEIRRDRVEPQSVSLSWREPIPAGA 482
Query: 460 PSGAVLDYEVKYHEKGAEGPSSVRFLKTSENRAELRGLKRGASYLVQVRARSEAGYGP-- 517
P +YE++Y+EKG + + +KT + LK Y+ Q+RA S GP
Sbjct: 483 PGANDTEYEIRYYEKG-QSEQTYSMVKTGAPTVTVTNLKPATRYVFQIRAASP---GPSW 538
Query: 518 ----FGQEHHSQTQLDESEGWREQLALIAGTAVVGVVLVLVVIVVAVLCLRKQSNGREAE 573
F QT + + G R+Q I T V L+++ V++VL + ++
Sbjct: 539 EAQSFNPSIEVQTLGEAASGSRDQSPAIVVTVVTISALLVLGSVMSVLAIWRRPCSYGKG 598
Query: 574 YSDKHGQYLIGHGTKV-----YIDPFTYEDPNEAVREFAKEIDVSYVKIEEVIGAGEFGE 628
D H + + KV ++DP + D +AV FAKE+D V +E +G G FGE
Sbjct: 599 GGDAHDEEELYFHFKVPTRRTFLDPQSCGDLLQAVHLFAKELDAKSVTLERSLGGGRFGE 658
Query: 629 VCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRLEGVVTNSMP 688
+C G L+ PG++E VA+ L+ ++ QR FL+EA +GQF+H +I+RLEGVVT
Sbjct: 659 LCCGCLQLPGRQELLVAVHMLRDSASDSQRLGFLAEALTLGQFDHSHIVRLEGVVTRGST 718
Query: 689 VMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIASGMRYLAEMSYVHRDLAARNILV 748
+MI+TE+M +GALD FLR ++GQ QL+G+L G+AS M+YL+EM YVHR LAAR++LV
Sbjct: 719 LMIVTEYMSHGALDGFLRRHEGQLVAGQLMGLLPGLASAMKYLSEMGYVHRGLAARHVLV 778
Query: 749 NSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRWTAPEAIAFRKFTSASDAWSYGI 808
+S+LVCK+S FG + S+ YT+ + G+ P W APE + F F+SASD WS+GI
Sbjct: 779 SSDLVCKISGFGRG---PRDRSEAVYTT-MSGRSPALWAAPETLQFGHFSSASDVWSFGI 834
Query: 809 VMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFP 868
+MWEVM+FGERPYWDMS QDVI A+E +RLPPP +CP LH+LMLDCWQKD RPRF
Sbjct: 835 IMWEVMAFGERPYWDMSGQDVIKAVEDGFRLPPPRNCPNLLHRLMLDCWQKDPGERPRFS 894
Query: 869 QVVSALDKMIRNPASLKIVARENGGASHPLLDQRQPHYSAFGSVGEWLRAIKMGRYEESF 928
Q+ S L KM+++P K PL D+ + +FGSVG WL A+ + RY++SF
Sbjct: 895 QIHSILSKMVQDPEPPKCALTTCPRPPTPLADRAFSTFPSFGSVGAWLEALDLCRYKDSF 954
Query: 929 AAAGFGSFELVSQISAEDLLRIGVTLAGHQKKILASVQHMKSQ 971
AAAG+GS E V++++A+DL+ +G++LA H++ +L+ + ++++
Sbjct: 955 AAAGYGSLEAVAEMTAQDLVSLGISLAEHREALLSGISALQAR 997
>gi|221316650 ephrin receptor EphA1 [Homo sapiens]
Length = 976
Score = 707 bits (1824), Expect = 0.0
Identities = 413/990 (41%), Positives = 575/990 (58%), Gaps = 51/990 (5%)
Query: 5 VLLCWASL---AAALEETLLNTKLETADLKWVTFPQVDGQWEELSGLDEEQHSVRTYEVC 61
VLL A L A A E TL++T +L W+ P DG E+ L+ + Y+ C
Sbjct: 12 VLLLCAPLPPGARAKEVTLMDTSKAQGELGWLLDPPKDGWSEQQQILNGTP--LYMYQDC 69
Query: 62 DVQRAPGQAHWLRTGWVPR-RGAVHVYATLRFTMLECLSLPRAGR--SCKETFTVFYYES 118
+Q HWLR+ W+ R A V+ L+FT+ +C S P CKETF + Y ES
Sbjct: 70 PMQGRRDTDHWLRSNWIYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCKETFNLLYMES 129
Query: 119 DADTATALTPAWMENPYIKVDTVAAEHLTRKRPGAEATGKVNVKTLRLGPLSKAGFYLAF 178
D D L + KV TVAA+ R + K+NV+ LG L++ G YLAF
Sbjct: 130 DQDVGIQLRRPLFQ----KVTTVAADQSFTIRDLVSGSVKLNVERCSLGRLTRRGLYLAF 185
Query: 179 QDQGACMALLSLHLFYKKCAQLTVNLTRFPETVPREL-VVPVAGSCVVDAVPAPGPS--P 235
+ GAC+AL+S+ +FY++C + L +FP+T+P +V VAG+C+ A +P PS P
Sbjct: 186 HNPGACVALVSVRVFYQRCPETLNGLAQFPDTLPGPAGLVEVAGTCLPHARASPRPSGAP 245
Query: 236 SLYCREDGQWAEQPVTGCSCAPGFEAAEGNTKCRACAQGTFKPLSGEGSCQPCPANSHSN 295
++C DG+W PV C C PG+E C AC G+++ C CP S +
Sbjct: 246 RMHCSPDGEWLV-PVGRCHCEPGYEEGGSGEACVACPSGSYRMDMDTPHCLTCPQQSTAE 304
Query: 296 TIGSAVCQCRVGYFRARTDPRGAPCTTPPSAPRSVVSRLNGSSLHLEWSAPLESGGREDL 355
+ G+ +C C G++RA + CT PPSAPR++ +G+ L L W P ++GGR+D+
Sbjct: 305 SEGATICTCESGHYRAPGEGPQVACTGPPSAPRNLSFSASGTQLSLRWEPPADTGGRQDV 364
Query: 356 TYALRCRECR----PGGSCAPCGGDLTFDPGPRDLVEPWVVVRGLRPDFTYTFEVTALNG 411
Y++RC +C+ GG C PCG + F PG R L P V V GL P YTF V A NG
Sbjct: 365 RYSVRCSQCQGTAQDGGPCQPCGVGVHFSPGARGLTTPAVHVNGLEPYANYTFNVEAQNG 424
Query: 412 VSSLATGPVPFEPVNVTTDREVPPAVSDIRVTRSSPSSLSLAWAV--PRAPSGAVLDYEV 469
VS L + V+++ + +R+ + P L L WA PR+P GA L YE+
Sbjct: 425 VSGLGSSGHASTSVSISMGHAESLSGLSLRLVKKEPRQLELTWAGSRPRSP-GANLTYEL 483
Query: 470 KYHEKGAEGPSSVRFLKTSENRAELRGLKRGASYLVQVRARSEAGYGPFGQEHHSQTQLD 529
+ E R+ E R L L+ +Y+V+VR + G GPF +H +T
Sbjct: 484 HVLNQDEE-----RYQMVLEPRVLLTELQPDTTYIVRVRMLTPLGPGPFSPDHEFRTSPP 538
Query: 530 ESEGWR--EQLALIAGTAVVGVVLVLVVIVVAVLCLRKQSNGREAEYS---DKHGQYLIG 584
S G E +A+I G ++G L+L ++V ++Q R+ + + D+ + +
Sbjct: 539 VSRGLTGGEIVAVIFGL-LLGAALLLGILVFRSRRAQRQRQQRQRDRATDVDREDKLWL- 596
Query: 585 HGTKVYIDPFTYEDPNEAVREFAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCV 644
K Y+D YEDP + +F +E+D +++ ++ VIG GEFGEV RG L+ P + V
Sbjct: 597 ---KPYVDLQAYEDPAQGALDFTRELDPAWLMVDTVIGEGEFGEVYRGTLRLPSQDCKTV 653
Query: 645 AIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSF 704
AIKTLK Q FL EA+IMGQF HP+I+ LEGVVT P+MI+TEFMENGALD+F
Sbjct: 654 AIKTLKDTSPGGQWWNFLREATIMGQFSHPHILHLEGVVTKRKPIMIITEFMENGALDAF 713
Query: 705 LRLNDGQFTVIQLVGMLRGIASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRF 764
LR + Q QLV ML+GIASGM YL+ +YVHRDLAARNILVN NL CKVSDFGL+R
Sbjct: 714 LREREDQLVPGQLVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQNLCCKVSDFGLTRL 773
Query: 765 LEENSSDPTYTSSLGGKIPIRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDM 824
L++ D TY + GGKIPIRWTAPEAIA R FT+ASD WS+GIVMWEV+SFG++PY +M
Sbjct: 774 LDD--FDGTYETQ-GGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEM 830
Query: 825 SNQDVINAIEQDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKMIRNPASL 884
SNQ+V+ +IE YRLPPP DCP L++LM +CW DR RP F ++ + L++++ NP SL
Sbjct: 831 SNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKLQAHLEQLLANPHSL 890
Query: 885 KIVARENGGASHPLLDQRQPHYSA-----FGSVGEWLRAIKMGRYEESFAAAGFGSFELV 939
+ +A + P + R P S + +V EWL +I+M RY F +AG + E V
Sbjct: 891 RTIANFD-----PRMTLRLPSLSGSDGIPYRTVSEWLESIRMKRYILHFHSAGLDTMECV 945
Query: 940 SQISAEDLLRIGVTLAGHQKKILASVQHMK 969
+++AEDL ++G+TL GHQK+IL S+Q K
Sbjct: 946 LELTAEDLTQMGITLPGHQKRILCSIQGFK 975
>gi|32967314 ephrin receptor EphA3 isoform b precursor [Homo
sapiens]
Length = 539
Score = 384 bits (986), Expect = e-106
Identities = 205/516 (39%), Positives = 301/516 (58%), Gaps = 16/516 (3%)
Query: 17 EETLLNTKLETADLKWVTFPQVDGQWEELSGLDEEQHSVRTYEVCDVQRAPGQAHWLRTG 76
E LL++K +L W+++P WEE+SG+DE +RTY+VC+V Q +WLRT
Sbjct: 29 EVNLLDSKTIQGELGWISYPSHG--WEEISGVDEHYTPIRTYQVCNVMDH-SQNNWLRTN 85
Query: 77 WVPRRGAVHVYATLRFTMLECLSLPRAGRSCKETFTVFYYESDADTATALTPAWMENPYI 136
WVPR A +Y L+FT+ +C S+P +CKETF ++Y ESD D + E+ +
Sbjct: 86 WVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVK----FREHQFT 141
Query: 137 KVDTVAAEHLTRKRPGAEATGKVNVKTLRLGPLSKAGFYLAFQDQGACMALLSLHLFYKK 196
K+DT+AA+ + + K+N + +GP++K GFYLAFQD GAC+AL+S+ +++KK
Sbjct: 142 KIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKK 201
Query: 197 CAQLTVNLTRFPETVPREL--VVPVAGSCVVDAVPAPGPSPSLYCREDGQWAEQPVTGCS 254
C NL FP+TVP + +V V GSCV ++ P +YC +G+W P+ CS
Sbjct: 202 CPFTVKNLAMFPDTVPMDSQSLVEVRGSCVNNSKEED--PPRMYCSTEGEWLV-PIGKCS 258
Query: 255 CAPGFEAAEGNTKCRACAQGTFKPLSGEGSCQPCPANSHSNTIGSAVCQCRVGYFRARTD 314
C G+E E C+AC G +K L G C CP +S + GS C+C YFRA D
Sbjct: 259 CNAGYE--ERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKD 316
Query: 315 PRGAPCTTPPSAPRSVVSRLNGSSLHLEWSAPLESGGREDLTYALRCRECRPG-GSCAPC 373
P CT PPS+PR+V+S +N +S+ L+WS PL++GGR+D+T+ + C++C C PC
Sbjct: 317 PPSMACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPC 376
Query: 374 GGDLTFDPGPRDLVEPWVVVRGLRPDFTYTFEVTALNGVSSLATGPVPFEPVNVTTDREV 433
++ F P L V V L YTFE+ A+NGVS L++ P F V++TT++
Sbjct: 377 SPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAA 436
Query: 434 PPAVSDIRVTRSSPSSLSLAWAVPRAPSGAVLDYEVKYHEKGAEGPSSVRFLKTSENRAE 493
P V I+ R+S +S+SL+W P P+G +LDYEVKY+EK E +S L+
Sbjct: 437 PSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEK-QEQETSYTILRARGTNVT 495
Query: 494 LRGLKRGASYLVQVRARSEAGYGPFGQEHHSQTQLD 529
+ LK Y+ Q+RAR+ AGYG ++ +T D
Sbjct: 496 ISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPD 531
>gi|55770892 ephrin receptor EphA8 isoform 2 precursor [Homo
sapiens]
Length = 495
Score = 314 bits (804), Expect = 3e-85
Identities = 178/463 (38%), Positives = 251/463 (54%), Gaps = 27/463 (5%)
Query: 13 AAALEETLLNTKLETADLKWVTFPQVDGQWEELSGLDEEQHSVRTYEVCDVQRAPGQAHW 72
AA E LL+T D W+T+P W+ ++ +DE + TY+VC+V +P Q +W
Sbjct: 27 AARGEVNLLDTSTIHGDWGWLTYPAHG--WDSINEVDESFQPIHTYQVCNVM-SPNQNNW 83
Query: 73 LRTGWVPRRGAVHVYATLRFTMLECLSLPRAGRSCKETFTVFYYESDADTATALTPAWME 132
LRT WVPR GA VYA ++FT+ +C S+P +CKETF ++Y ESD D L + E
Sbjct: 84 LRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESDRD----LGASTQE 139
Query: 133 NPYIKVDTVAAEHLTRKRPGAEATGKVNVKTLRLGPLSKAGFYLAFQDQGACMALLSLHL 192
+ ++K+DT+AA+ K+N + +GPLSK GFYLAFQD GAC+A+LSL +
Sbjct: 140 SQFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRI 199
Query: 193 FYKKCAQLTVNLTRFPETVP---RELVVPVAGSCVVDAVPAPGPSPSLYCREDGQWAEQP 249
+YKKC + NL F E V +V V G CV + +P +YC +G+W P
Sbjct: 200 YYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEERD--TPKMYCSAEGEWLV-P 256
Query: 250 VTGCSCAPGFEAAEGNTKCRACAQGTFKPLSGEGSCQPCPANSHSNTIGSAVCQCRVGYF 309
+ C C+ G+E E C AC G +K G+ C CP +SHS + C C + Y+
Sbjct: 257 IGKCVCSAGYE--ERRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYY 314
Query: 310 RARTDPRGAPCTTPPSAPRSVVSRLNGSSLHLEWSAPLESGGREDLTYALRCRECRPGGS 369
RA DP + CT PPSAP +++S +NG+S+ LEW+ PL+ GGR D+TY CR C S
Sbjct: 315 RAALDPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCPWALS 374
Query: 370 -CAPCGGDLTFDPGPRDLVEPWVVVRGLRPDFTYTFEVTALNGVSSLATGPVPFEPVNVT 428
C CG F P LV+ ++V L Y+F + A+NGVS L+ P VN+T
Sbjct: 375 RCEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAVVNIT 434
Query: 429 TD-----------REVPPAVSDIRVTRSSPSSLSLAWAVPRAP 460
T+ R PPA +R S+ + WA + P
Sbjct: 435 TNQAGRRRNSVPQRPGPPASPASDPSRDQSSAGDVLWAFRQVP 477
>gi|27886593 PTK2 protein tyrosine kinase 2 isoform b [Homo sapiens]
Length = 1074
Score = 225 bits (574), Expect = 1e-58
Identities = 114/270 (42%), Positives = 167/270 (61%), Gaps = 5/270 (1%)
Query: 609 EIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIM 668
EI +++ IG G+FG+V +G +P VAIKT K ++ R +FL EA M
Sbjct: 438 EIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTM 497
Query: 669 GQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIASGM 728
QF+HP+I++L GV+T + PV I+ E G L SFL++ + L+ +++ +
Sbjct: 498 RQFDHPHIVKLIGVITEN-PVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTAL 556
Query: 729 RYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRWTA 788
YL +VHRD+AARN+LV+SN K+ DFGLSR++E D TY + GK+PI+W A
Sbjct: 557 AYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYME----DSTYYKASKGKLPIKWMA 612
Query: 789 PEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPPDCPTS 848
PE+I FR+FTSASD W +G+ MWE++ G +P+ + N DVI IE RLP PP+CP +
Sbjct: 613 PESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPT 672
Query: 849 LHQLMLDCWQKDRNARPRFPQVVSALDKMI 878
L+ LM CW D + RPRF ++ + L ++
Sbjct: 673 LYSLMTKCWAYDPSRRPRFTELKAQLSTIL 702
>gi|24476013 PTK2 protein tyrosine kinase 2 isoform a [Homo sapiens]
Length = 1052
Score = 225 bits (574), Expect = 1e-58
Identities = 114/270 (42%), Positives = 167/270 (61%), Gaps = 5/270 (1%)
Query: 609 EIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIM 668
EI +++ IG G+FG+V +G +P VAIKT K ++ R +FL EA M
Sbjct: 416 EIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTM 475
Query: 669 GQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIASGM 728
QF+HP+I++L GV+T + PV I+ E G L SFL++ + L+ +++ +
Sbjct: 476 RQFDHPHIVKLIGVITEN-PVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTAL 534
Query: 729 RYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRWTA 788
YL +VHRD+AARN+LV+SN K+ DFGLSR++E D TY + GK+PI+W A
Sbjct: 535 AYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYME----DSTYYKASKGKLPIKWMA 590
Query: 789 PEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPPDCPTS 848
PE+I FR+FTSASD W +G+ MWE++ G +P+ + N DVI IE RLP PP+CP +
Sbjct: 591 PESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPT 650
Query: 849 LHQLMLDCWQKDRNARPRFPQVVSALDKMI 878
L+ LM CW D + RPRF ++ + L ++
Sbjct: 651 LYSLMTKCWAYDPSRRPRFTELKAQLSTIL 680
>gi|30795229 hemopoietic cell kinase isoform p61HCK [Homo sapiens]
Length = 526
Score = 223 bits (569), Expect = 5e-58
Identities = 118/284 (41%), Positives = 177/284 (62%), Gaps = 12/284 (4%)
Query: 593 PFTYEDPNEAVREFAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGG 652
P P + + A EI +K+E+ +GAG+FGEV A K + VA+KT+K G
Sbjct: 240 PCMSSKPQKPWEKDAWEIPRESLKLEKKLGAGQFGEVWM----ATYNKHTKVAVKTMKPG 295
Query: 653 YTERQRREFLSEASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLNDGQF 712
+ FL+EA++M +H +++L VVT P+ I+TEFM G+L FL+ ++G
Sbjct: 296 SMSVEA--FLAEANVMKTLQHDKLVKLHAVVTKE-PIYIITEFMAKGSLLDFLKSDEGSK 352
Query: 713 TVI-QLVGMLRGIASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSD 771
+ +L+ IA GM ++ + +Y+HRDL A NILV+++LVCK++DFGL+R +E+N
Sbjct: 353 QPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLARVIEDNE-- 410
Query: 772 PTYTSSLGGKIPIRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVIN 831
YT+ G K PI+WTAPEAI F FT SD WS+GI++ E++++G PY MSN +VI
Sbjct: 411 --YTAREGAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIR 468
Query: 832 AIEQDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSALD 875
A+E+ YR+P P +CP L+ +M+ CW+ RP F + S LD
Sbjct: 469 ALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLD 512
>gi|4885661 viral oncogene yes-1 homolog 1 [Homo sapiens]
Length = 543
Score = 222 bits (565), Expect = 2e-57
Identities = 123/282 (43%), Positives = 170/282 (60%), Gaps = 12/282 (4%)
Query: 595 TYEDPNEAVREFAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYT 654
T + + + + A EI +++E +G G FGEV G K VAIKTLK G
Sbjct: 257 TVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTK----VAIKTLKPG-- 310
Query: 655 ERQRREFLSEASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLNDGQFTV 714
FL EA IM + H ++ L VV+ P+ I+TEFM G+L FL+ DG++
Sbjct: 311 TMMPEAFLQEAQIMKKLRHDKLVPLYAVVSEE-PIYIVTEFMSKGSLLDFLKEGDGKYLK 369
Query: 715 I-QLVGMLRGIASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPT 773
+ QLV M IA GM Y+ M+Y+HRDL A NILV NLVCK++DFGL+R +E+N
Sbjct: 370 LPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLVCKIADFGLARLIEDNE---- 425
Query: 774 YTSSLGGKIPIRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAI 833
YT+ G K PI+WTAPEA + +FT SD WS+GI+ E+++ G PY M N++V+ +
Sbjct: 426 YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQV 485
Query: 834 EQDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSALD 875
E+ YR+P P CP SLH+LM CW+KD + RP F + S L+
Sbjct: 486 ERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYIQSFLE 527
>gi|38202217 proto-oncogene tyrosine-protein kinase SRC [Homo
sapiens]
Length = 536
Score = 221 bits (564), Expect = 2e-57
Identities = 127/303 (41%), Positives = 179/303 (59%), Gaps = 15/303 (4%)
Query: 574 YSDKHGQYLIGHGTKVYIDPFTYEDPNEAVREFAKEIDVSYVKIEEVIGAGEFGEVCRGR 633
Y KH L T V T + + + + A EI +++E +G G FGEV G
Sbjct: 232 YYSKHADGLCHRLTTVCP---TSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGT 288
Query: 634 LKAPGKKESCVAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRLEGVVTNSMPVMILT 693
+ VAIKTLK G + FL EA +M + H +++L VV+ P+ I+T
Sbjct: 289 WNGTTR----VAIKTLKPGTMSPEA--FLQEAQVMKKLRHEKLVQLYAVVSEE-PIYIVT 341
Query: 694 EFMENGALDSFLRLNDGQFTVI-QLVGMLRGIASGMRYLAEMSYVHRDLAARNILVNSNL 752
E+M G+L FL+ G++ + QLV M IASGM Y+ M+YVHRDL A NILV NL
Sbjct: 342 EYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENL 401
Query: 753 VCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRWTAPEAIAFRKFTSASDAWSYGIVMWE 812
VCKV+DFGL+R +E+N YT+ G K PI+WTAPEA + +FT SD WS+GI++ E
Sbjct: 402 VCKVADFGLARLIEDNE----YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTE 457
Query: 813 VMSFGERPYWDMSNQDVINAIEQDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVVS 872
+ + G PY M N++V++ +E+ YR+P PP+CP SLH LM CW+K+ RP F + +
Sbjct: 458 LTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQA 517
Query: 873 ALD 875
L+
Sbjct: 518 FLE 520
>gi|4885609 proto-oncogene tyrosine-protein kinase SRC [Homo
sapiens]
Length = 536
Score = 221 bits (564), Expect = 2e-57
Identities = 127/303 (41%), Positives = 179/303 (59%), Gaps = 15/303 (4%)
Query: 574 YSDKHGQYLIGHGTKVYIDPFTYEDPNEAVREFAKEIDVSYVKIEEVIGAGEFGEVCRGR 633
Y KH L T V T + + + + A EI +++E +G G FGEV G
Sbjct: 232 YYSKHADGLCHRLTTVCP---TSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGT 288
Query: 634 LKAPGKKESCVAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRLEGVVTNSMPVMILT 693
+ VAIKTLK G + FL EA +M + H +++L VV+ P+ I+T
Sbjct: 289 WNGTTR----VAIKTLKPGTMSPEA--FLQEAQVMKKLRHEKLVQLYAVVSEE-PIYIVT 341
Query: 694 EFMENGALDSFLRLNDGQFTVI-QLVGMLRGIASGMRYLAEMSYVHRDLAARNILVNSNL 752
E+M G+L FL+ G++ + QLV M IASGM Y+ M+YVHRDL A NILV NL
Sbjct: 342 EYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENL 401
Query: 753 VCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRWTAPEAIAFRKFTSASDAWSYGIVMWE 812
VCKV+DFGL+R +E+N YT+ G K PI+WTAPEA + +FT SD WS+GI++ E
Sbjct: 402 VCKVADFGLARLIEDNE----YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTE 457
Query: 813 VMSFGERPYWDMSNQDVINAIEQDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVVS 872
+ + G PY M N++V++ +E+ YR+P PP+CP SLH LM CW+K+ RP F + +
Sbjct: 458 LTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQA 517
Query: 873 ALD 875
L+
Sbjct: 518 FLE 520
>gi|4503823 protein-tyrosine kinase fyn isoform a [Homo sapiens]
Length = 537
Score = 218 bits (554), Expect = 3e-56
Identities = 114/268 (42%), Positives = 170/268 (63%), Gaps = 12/268 (4%)
Query: 609 EIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIM 668
EI +++ + +G G+FGEV G K VAIKTLK G + FL EA IM
Sbjct: 265 EIPRESLQLIKRLGNGQFGEVWMGTWNGNTK----VAIKTLKPGTMSPE--SFLEEAQIM 318
Query: 669 GQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLNDGQFTVI-QLVGMLRGIASG 727
+ +H +++L VV+ P+ I+TE+M G+L FL+ +G+ + LV M +A+G
Sbjct: 319 KKLKHDKLVQLYAVVSEE-PIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAG 377
Query: 728 MRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRWT 787
M Y+ M+Y+HRDL + NILV + L+CK++DFGL+R +E+N YT+ G K PI+WT
Sbjct: 378 MAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNE----YTARQGAKFPIKWT 433
Query: 788 APEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPPDCPT 847
APEA + +FT SD WS+GI++ E+++ G PY M+N++V+ +E+ YR+P P DCP
Sbjct: 434 APEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPI 493
Query: 848 SLHQLMLDCWQKDRNARPRFPQVVSALD 875
SLH+LM+ CW+KD RP F + S L+
Sbjct: 494 SLHELMIHCWKKDPEERPTFEYLQSFLE 521
>gi|112789548 lymphocyte-specific protein tyrosine kinase precursor
[Homo sapiens]
Length = 509
Score = 216 bits (549), Expect = 1e-55
Identities = 119/284 (41%), Positives = 173/284 (60%), Gaps = 12/284 (4%)
Query: 593 PFTYEDPNEAVREFAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGG 652
P + P + E E+ +K+ E +GAG+FGEV G K VA+K+LK G
Sbjct: 223 PCQTQKPQKPWWEDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTK----VAVKSLKQG 278
Query: 653 YTERQRREFLSEASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLNDG-Q 711
FL+EA++M Q +H ++RL VVT P+ I+TE+MENG+L FL+ G +
Sbjct: 279 SMSPDA--FLAEANLMKQLQHQRLVRLYAVVTQE-PIYIITEYMENGSLVDFLKTPSGIK 335
Query: 712 FTVIQLVGMLRGIASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSD 771
T+ +L+ M IA GM ++ E +Y+HRDL A NILV+ L CK++DFGL+R +E+N
Sbjct: 336 LTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNE-- 393
Query: 772 PTYTSSLGGKIPIRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVIN 831
YT+ G K PI+WTAPEAI + FT SD WS+GI++ E+++ G PY M+N +VI
Sbjct: 394 --YTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQ 451
Query: 832 AIEQDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSALD 875
+E+ YR+ P +CP L+QLM CW++ RP F + S L+
Sbjct: 452 NLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLE 495
>gi|112789546 lymphocyte-specific protein tyrosine kinase precursor
[Homo sapiens]
Length = 509
Score = 216 bits (549), Expect = 1e-55
Identities = 119/284 (41%), Positives = 173/284 (60%), Gaps = 12/284 (4%)
Query: 593 PFTYEDPNEAVREFAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGG 652
P + P + E E+ +K+ E +GAG+FGEV G K VA+K+LK G
Sbjct: 223 PCQTQKPQKPWWEDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTK----VAVKSLKQG 278
Query: 653 YTERQRREFLSEASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLNDG-Q 711
FL+EA++M Q +H ++RL VVT P+ I+TE+MENG+L FL+ G +
Sbjct: 279 SMSPDA--FLAEANLMKQLQHQRLVRLYAVVTQE-PIYIITEYMENGSLVDFLKTPSGIK 335
Query: 712 FTVIQLVGMLRGIASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSD 771
T+ +L+ M IA GM ++ E +Y+HRDL A NILV+ L CK++DFGL+R +E+N
Sbjct: 336 LTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNE-- 393
Query: 772 PTYTSSLGGKIPIRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVIN 831
YT+ G K PI+WTAPEAI + FT SD WS+GI++ E+++ G PY M+N +VI
Sbjct: 394 --YTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQ 451
Query: 832 AIEQDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSALD 875
+E+ YR+ P +CP L+QLM CW++ RP F + S L+
Sbjct: 452 NLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLE 495
>gi|162287326 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog
isoform B [Homo sapiens]
Length = 491
Score = 216 bits (549), Expect = 1e-55
Identities = 113/270 (41%), Positives = 168/270 (62%), Gaps = 11/270 (4%)
Query: 607 AKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEAS 666
A EI +K+ + +GAG+FGEV G K VA+KTLK G Q FL EA+
Sbjct: 218 AWEIPRESIKLVKRLGAGQFGEVWMGYYNNSTK----VAVKTLKPGTMSVQA--FLEEAN 271
Query: 667 IMGQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLNDGQFTVI-QLVGMLRGIA 725
+M +H ++RL VVT P+ I+TE+M G+L FL+ ++G ++ +L+ IA
Sbjct: 272 LMKTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIA 331
Query: 726 SGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIR 785
GM Y+ +Y+HRDL A N+LV+ +L+CK++DFGL+R +E+N YT+ G K PI+
Sbjct: 332 EGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNE----YTAREGAKFPIK 387
Query: 786 WTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPPDC 845
WTAPEAI F FT SD WS+GI+++E++++G+ PY +N DV+ A+ Q YR+P +C
Sbjct: 388 WTAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMPRVENC 447
Query: 846 PTSLHQLMLDCWQKDRNARPRFPQVVSALD 875
P L+ +M CW++ RP F + S LD
Sbjct: 448 PDELYDIMKMCWKEKAEERPTFDYLQSVLD 477
>gi|4505055 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog
isoform A [Homo sapiens]
Length = 512
Score = 216 bits (549), Expect = 1e-55
Identities = 113/270 (41%), Positives = 168/270 (62%), Gaps = 11/270 (4%)
Query: 607 AKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEAS 666
A EI +K+ + +GAG+FGEV G K VA+KTLK G Q FL EA+
Sbjct: 239 AWEIPRESIKLVKRLGAGQFGEVWMGYYNNSTK----VAVKTLKPGTMSVQA--FLEEAN 292
Query: 667 IMGQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLNDGQFTVI-QLVGMLRGIA 725
+M +H ++RL VVT P+ I+TE+M G+L FL+ ++G ++ +L+ IA
Sbjct: 293 LMKTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIA 352
Query: 726 SGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIR 785
GM Y+ +Y+HRDL A N+LV+ +L+CK++DFGL+R +E+N YT+ G K PI+
Sbjct: 353 EGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNE----YTAREGAKFPIK 408
Query: 786 WTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPPDC 845
WTAPEAI F FT SD WS+GI+++E++++G+ PY +N DV+ A+ Q YR+P +C
Sbjct: 409 WTAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMPRVENC 468
Query: 846 PTSLHQLMLDCWQKDRNARPRFPQVVSALD 875
P L+ +M CW++ RP F + S LD
Sbjct: 469 PDELYDIMKMCWKEKAEERPTFDYLQSVLD 498
>gi|23510362 protein-tyrosine kinase fyn isoform b [Homo sapiens]
Length = 534
Score = 214 bits (546), Expect = 2e-55
Identities = 112/260 (43%), Positives = 165/260 (63%), Gaps = 12/260 (4%)
Query: 617 IEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIMGQFEHPNI 676
+E+ +G G F EV G K VAIKTLK G + FL EA IM + +H +
Sbjct: 270 LEKKLGQGCFAEVWLGTWNGNTK----VAIKTLKPGTMSPE--SFLEEAQIMKKLKHDKL 323
Query: 677 IRLEGVVTNSMPVMILTEFMENGALDSFLRLNDGQFTVI-QLVGMLRGIASGMRYLAEMS 735
++L VV+ P+ I+TE+M G+L FL+ +G+ + LV M +A+GM Y+ M+
Sbjct: 324 VQLYAVVSEE-PIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMN 382
Query: 736 YVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRWTAPEAIAFR 795
Y+HRDL + NILV + L+CK++DFGL+R +E+N YT+ G K PI+WTAPEA +
Sbjct: 383 YIHRDLRSANILVGNGLICKIADFGLARLIEDNE----YTARQGAKFPIKWTAPEAALYG 438
Query: 796 KFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPPDCPTSLHQLMLD 855
+FT SD WS+GI++ E+++ G PY M+N++V+ +E+ YR+P P DCP SLH+LM+
Sbjct: 439 RFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIH 498
Query: 856 CWQKDRNARPRFPQVVSALD 875
CW+KD RP F + S L+
Sbjct: 499 CWKKDPEERPTFEYLQSFLE 518
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,254,603
Number of Sequences: 37866
Number of extensions: 2123706
Number of successful extensions: 10278
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 606
Number of HSP's successfully gapped in prelim test: 440
Number of HSP's that attempted gapping in prelim test: 6259
Number of HSP's gapped (non-prelim): 2703
length of query: 987
length of database: 18,247,518
effective HSP length: 112
effective length of query: 875
effective length of database: 14,006,526
effective search space: 12255710250
effective search space used: 12255710250
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.