Guide to the Human Genome
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Search of human proteins with 32483410

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|32483410 vitamin D-binding protein precursor [Homo sapiens]
         (474 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|32483410 vitamin D-binding protein precursor [Homo sapiens]        969   0.0  
gi|4502027 albumin preproprotein [Homo sapiens]                       151   1e-36
gi|4501987 afamin precursor [Homo sapiens]                            120   2e-27
gi|4501989 alpha-fetoprotein precursor [Homo sapiens]                 106   5e-23
gi|4826694 integral membrane protein DGCR2 [Homo sapiens]              32   0.96 
gi|130980075 centromere protein J [Homo sapiens]                       32   0.96 
gi|191252801 WDFY family member 4 [Homo sapiens]                       30   4.8  
gi|26190614 rhotekin 2 [Homo sapiens]                                  30   4.8  
gi|169207319 PREDICTED: hypothetical protein [Homo sapiens]            30   6.2  
gi|169207756 PREDICTED: hypothetical protein [Homo sapiens]            30   6.2  
gi|169207046 PREDICTED: hypothetical protein [Homo sapiens]            30   6.2  
gi|33286418 pyruvate kinase, muscle isoform M2 [Homo sapiens]          29   8.1  
gi|33286422 pyruvate kinase, muscle isoform M1 [Homo sapiens]          29   8.1  
gi|33286420 pyruvate kinase, muscle isoform M1 [Homo sapiens]          29   8.1  
gi|169218111 PREDICTED: similar to pyruvate kinase, muscle [Homo...    29   8.1  
gi|122937343 platelet endothelial aggregation receptor 1 [Homo s...    29   8.1  
gi|116686120 periaxin isoform 2 [Homo sapiens]                         29   8.1  
gi|110347437 latent transforming growth factor beta binding prot...    29   8.1  
gi|110347412 latent transforming growth factor beta binding prot...    29   8.1  
gi|110347431 latent transforming growth factor beta binding prot...    29   8.1  
gi|14589929 protocadherin 18 precursor [Homo sapiens]                  29   8.1  
gi|30794372 polybromo 1 isoform 1 [Homo sapiens]                       29   8.1  
gi|93102371 polybromo 1 isoform 2 [Homo sapiens]                       29   8.1  
gi|41281917 polybromo 1 isoform 4 [Homo sapiens]                       29   8.1  

>gi|32483410 vitamin D-binding protein precursor [Homo sapiens]
          Length = 474

 Score =  969 bits (2506), Expect = 0.0
 Identities = 474/474 (100%), Positives = 474/474 (100%)

Query: 1   MKRVLVLLLAVAFGHALERGRDYEKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQV 60
           MKRVLVLLLAVAFGHALERGRDYEKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQV
Sbjct: 1   MKRVLVLLLAVAFGHALERGRDYEKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQV 60

Query: 61  SQLVKEVVSLTEACCAEGADPDCYDTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERK 120
           SQLVKEVVSLTEACCAEGADPDCYDTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERK
Sbjct: 61  SQLVKEVVSLTEACCAEGADPDCYDTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERK 120

Query: 121 LCMAALKHQPQEFPTYVEPTNDEICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTK 180
           LCMAALKHQPQEFPTYVEPTNDEICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTK
Sbjct: 121 LCMAALKHQPQEFPTYVEPTNDEICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTK 180

Query: 181 SYLSMVGSCCTSASPTVCFLKERLQLKHLSLLTTLSNRVCSQYAAYGEKKSRLSNLIKLA 240
           SYLSMVGSCCTSASPTVCFLKERLQLKHLSLLTTLSNRVCSQYAAYGEKKSRLSNLIKLA
Sbjct: 181 SYLSMVGSCCTSASPTVCFLKERLQLKHLSLLTTLSNRVCSQYAAYGEKKSRLSNLIKLA 240

Query: 241 QKVPTADLEDVLPLAEDITNILSKCCESASEDCMAKELPEHTVKLCDNLSTKNSKFEDCC 300
           QKVPTADLEDVLPLAEDITNILSKCCESASEDCMAKELPEHTVKLCDNLSTKNSKFEDCC
Sbjct: 241 QKVPTADLEDVLPLAEDITNILSKCCESASEDCMAKELPEHTVKLCDNLSTKNSKFEDCC 300

Query: 301 QEKTAMDVFVCTYFMPAAQLPELPDVELPTNKDVCDPGNTKVMDKYTFELSRRTHLPEVF 360
           QEKTAMDVFVCTYFMPAAQLPELPDVELPTNKDVCDPGNTKVMDKYTFELSRRTHLPEVF
Sbjct: 301 QEKTAMDVFVCTYFMPAAQLPELPDVELPTNKDVCDPGNTKVMDKYTFELSRRTHLPEVF 360

Query: 361 LSKVLEPTLKSLGECCDVEDSTTCFNAKGPLLKKELSSFIDKGQELCADYSENTFTEYKK 420
           LSKVLEPTLKSLGECCDVEDSTTCFNAKGPLLKKELSSFIDKGQELCADYSENTFTEYKK
Sbjct: 361 LSKVLEPTLKSLGECCDVEDSTTCFNAKGPLLKKELSSFIDKGQELCADYSENTFTEYKK 420

Query: 421 KLAERLKAKLPDATPTELAKLVNKHSDFASNCCSINSPPLYCDSEIDAELKNIL 474
           KLAERLKAKLPDATPTELAKLVNKHSDFASNCCSINSPPLYCDSEIDAELKNIL
Sbjct: 421 KLAERLKAKLPDATPTELAKLVNKHSDFASNCCSINSPPLYCDSEIDAELKNIL 474


>gi|4502027 albumin preproprotein [Homo sapiens]
          Length = 609

 Score =  151 bits (382), Expect = 1e-36
 Identities = 114/468 (24%), Positives = 206/468 (44%), Gaps = 21/468 (4%)

Query: 1   MKRVLVLLLAVAFGHALERG---RDYEKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTF 57
           MK V  + L   F  A  RG   RD  K++V   F  LG+E+F +L L+ +++      F
Sbjct: 1   MKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPF 60

Query: 58  EQVSQLVKEVVSLTEACCAEGADPDCYDTRTSALSAKSCESNSPFPVHPGTAECCTKEGL 117
           E   +LV EV    + C A+ +  +C  +  +    K C   +    +   A+CC K+  
Sbjct: 61  EDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEP 120

Query: 118 ERKLCMAALKHQPQEFPTYVEPTNDEICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVS 177
           ER  C    K      P  V P  D +C AF  + + +  ++++E +  +       L+ 
Sbjct: 121 ERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLF 180

Query: 178 YTKSYLSMVGSCCTSASPTVCFLKERLQLKHLSLLTTLSNRV-CSQYAAYGEKKSRLSNL 236
           + K Y +    CC +A    C L +  +L+     ++   R+ C+    +GE+  +   +
Sbjct: 181 FAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAV 240

Query: 237 IKLAQKVPTADLEDVLPLAEDITNILSKCCESASEDCMAKELPEHTVKLCDNLSTKNSKF 296
            +L+Q+ P A+  +V  L  D+T + ++CC     +C A +  +    +C+N  + +SK 
Sbjct: 241 ARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLEC-ADDRADLAKYICENQDSISSKL 299

Query: 297 EDCCQEKTAMDVFVCTYFMPAAQLP-ELPDV--ELPTNKDVCD---PGNTKVMDKYTFEL 350
           ++CC EK  ++   C   +   ++P +LP +  +   +KDVC          +  + +E 
Sbjct: 300 KECC-EKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEY 358

Query: 351 SRR-THLPEVFLSKVLEPTLKSLGECCDVEDSTTC----FNAKGPLLKKELSSFIDKGQE 405
           +RR      V L ++ +    +L +CC   D   C    F+   PL+ +E  + I +  E
Sbjct: 359 ARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLV-EEPQNLIKQNCE 417

Query: 406 LCADYSENTFTEYKKKLAERLKAKLPDATPTELAKLVNKHSDFASNCC 453
           L     E  F   +  L  R   K+P  +   L ++        S CC
Sbjct: 418 LFEQLGEYKF---QNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCC 462



 Score =  103 bits (256), Expect = 4e-22
 Identities = 88/389 (22%), Positives = 164/389 (42%), Gaps = 38/389 (9%)

Query: 29  CKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGADPDCYDTRT 88
           C      G+  F + ++   S++FP   F +VS+LV ++  +   CC  G   +C D R 
Sbjct: 224 CASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECC-HGDLLECADDRA 282

Query: 89  SALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQ--PQEFPT----YVEPTND 142
             L+   CE+     +     ECC K  LE+  C+A +++   P + P+    +VE  + 
Sbjct: 283 D-LAKYICENQDS--ISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVE--SK 337

Query: 143 EICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLKE 202
           ++C+ + +    +   F++EY+  +    + LL+   K+Y + +  CC +A P  C+ K 
Sbjct: 338 DVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKV 397

Query: 203 RLQLKHL-SLLTTLSNRVCSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDITNI 261
             + K L      L  + C  +   GE K + + L++  +KVP      ++ ++ ++  +
Sbjct: 398 FDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKV 457

Query: 262 LSKCC---ESASEDCMAKELPEHTVKLC--DNLSTKNSKFEDCCQEKTAMDVFVCTYFMP 316
            SKCC   E+    C    L     +LC     +  + +   CC E             P
Sbjct: 458 GSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNR-------RP 510

Query: 317 AAQLPELPDVELPT---------NKDVCD-PGNTKVMDKYTFELSRRTHLPEVF---LSK 363
                E+ +  +P          + D+C      + + K T  +    H P+     L  
Sbjct: 511 CFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKA 570

Query: 364 VLEPTLKSLGECCDVEDSTTCFNAKGPLL 392
           V++     + +CC  +D  TCF  +G  L
Sbjct: 571 VMDDFAAFVEKCCKADDKETCFAEEGKKL 599


>gi|4501987 afamin precursor [Homo sapiens]
          Length = 599

 Score =  120 bits (302), Expect = 2e-27
 Identities = 95/447 (21%), Positives = 185/447 (41%), Gaps = 19/447 (4%)

Query: 21  RDYEKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGAD 80
           RD E     ++F    +++   ++++ +++     TFE++ +LVK++V   + C A+   
Sbjct: 27  RDIENFNSTQKFI---EDNIEYITIIAFAQYVQEATFEEMEKLVKDMVEYKDRCMADKTL 83

Query: 81  PDCYDTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQPQEF-PTYVEP 139
           P+C     + L  K C      P     + CC+K   +R+LC    K     F P +   
Sbjct: 84  PECSKLPNNVLQEKICAMEG-LPQKHNFSHCCSKVDAQRRLCFFYNKKSDVGFLPPFPTL 142

Query: 140 TNDEICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCF 199
             +E C+A+  + +   N F++E +          L++    +  +  SCC   +   C 
Sbjct: 143 DPEEKCQAYESNRESLLNHFLYEVARRNPFVFAPTLLTVAVHFEEVAKSCCEEQNKVNCL 202

Query: 200 LKERLQL-KHLSLLTTLSNRVCSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDI 258
               + + ++L   ++    VC     +G K      +  L+QK P  + ++++ L ED+
Sbjct: 203 QTRAIPVTQYLKAFSSYQKHVCGALLKFGTKVVHFIYIAILSQKFPKIEFKELISLVEDV 262

Query: 259 TNILSKCCESASEDCMAKELPEHTVKLCDNLSTKNSKFEDCCQEKTAMDVFVCTYFMPAA 318
           ++    CCE     C+ ++  +    +C    + +SK ++CC EK   +   C       
Sbjct: 263 SSNYDGCCEGDVVQCI-RDTSKVMNHICSKQDSISSKIKECC-EKKIPERGQCIINSNKD 320

Query: 319 QLPE---LPDVELPTNKDVC---DPGNTKVMDKYTFELSRR---THLPEVFLSKVLEPTL 369
             P+   L + +   +++VC   D        K+TFE SRR     +PE  L ++++   
Sbjct: 321 DRPKDLSLREGKFTDSENVCQERDADPDTFFAKFTFEYSRRHPDLSIPE--LLRIVQIYK 378

Query: 370 KSLGECCDVEDSTTCFNAKGPLLKKELSSFIDKGQELCADYSENTFTEYKKKLAERLKAK 429
             L  CC+ E+   C+        +     +   Q+ C  +        K     RL   
Sbjct: 379 DLLRNCCNTENPPGCYRYAEDKFNETTEKSLKMVQQECKHFQNLGKDGLKYHYLIRLTKI 438

Query: 430 LPDATPTELAKLVNKHSDFASNCCSIN 456
            P  +  EL  L  K     + CC+++
Sbjct: 439 APQLSTEELVSLGEKMVTAFTTCCTLS 465



 Score = 86.3 bits (212), Expect = 6e-17
 Identities = 82/396 (20%), Positives = 159/396 (40%), Gaps = 21/396 (5%)

Query: 10  AVAFGHALERGRDYEKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVS 69
           A+     L+    Y+K+ VC      G +    + + + S+KFP   F+++  LV++V S
Sbjct: 206 AIPVTQYLKAFSSYQKH-VCGALLKFGTKVVHFIYIAILSQKFPKIEFKELISLVEDVSS 264

Query: 70  LTEACCAEGADPDCYDTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCM--AALK 127
             + CC EG    C    +  ++    + +S   +     ECC K+  ER  C+  +   
Sbjct: 265 NYDGCC-EGDVVQCIRDTSKVMNHICSKQDS---ISSKIKECCEKKIPERGQCIINSNKD 320

Query: 128 HQPQEFPTYVEPTNDE--ICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSM 185
            +P++         D   +C+    DP  +  +F +EYS  +    +  L+   + Y  +
Sbjct: 321 DRPKDLSLREGKFTDSENVCQERDADPDTFFAKFTFEYSRRHPDLSIPELLRIVQIYKDL 380

Query: 186 VGSCCTSASPTVCFLKERLQLKHLSLLTT-LSNRVCSQYAAYGEKKSRLSNLIKLAQKVP 244
           + +CC + +P  C+     +    +  +  +  + C  +   G+   +   LI+L +  P
Sbjct: 381 LRNCCNTENPPGCYRYAEDKFNETTEKSLKMVQQECKHFQNLGKDGLKYHYLIRLTKIAP 440

Query: 245 TADLEDVLPLAEDITNILSKCCESASEDCMAKELPEHTV-KLC--DNLSTKNSKFEDCCQ 301
               E+++ L E +    + CC  + E      L +    +LC  +   T N   + CC+
Sbjct: 441 QLSTEELVSLGEKMVTAFTTCCTLSEEFACVDNLADLVFGELCGVNENRTINPAVDHCCK 500

Query: 302 EKTAMDVFVCTYFMPAAQL---PELPDVELPTNKDVCDPGNTKVM---DKYTFELSRRTH 355
              A     C   + A +    P         + D+C   N ++    D++   L +  H
Sbjct: 501 TNFAFRR-PCFESLKADKTYVPPPFSQDLFTFHADMCQSQNEELQRKTDRFLVNLVKLKH 559

Query: 356 -LPEVFLSKVLEPTLKSLGECCDVEDSTTCFNAKGP 390
            L +  L  +       + +CC  E    CFN + P
Sbjct: 560 ELTDEELQSLFTNFANVVDKCCKAESPEVCFNEESP 595



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 75/359 (20%), Positives = 134/359 (37%), Gaps = 50/359 (13%)

Query: 133 FPTYVEPTNDEICEAFRKDPKEYANQFMWEYST-NYGQAPLSLLVSYTKSYLSMVG---- 187
           F  YV+    E  E   KD  EY ++ M + +     + P ++L    +   +M G    
Sbjct: 51  FAQYVQEATFEEMEKLVKDMVEYKDRCMADKTLPECSKLPNNVL---QEKICAMEGLPQK 107

Query: 188 ----SCCTS--ASPTVCFL-KERLQLKHLSLLTTLSNRVCSQYAAYGEKKSRLSN--LIK 238
                CC+   A   +CF   ++  +  L    TL      Q  AY   +  L N  L +
Sbjct: 108 HNFSHCCSKVDAQRRLCFFYNKKSDVGFLPPFPTLDPEEKCQ--AYESNRESLLNHFLYE 165

Query: 239 LAQKVPTADLEDVLPLAEDITNILSKCCESASE-DCMAKELPEHTVKLCDNLSTKNSKFE 297
           +A++ P      +L +A     +   CCE  ++ +C    L    + +   L   +S  +
Sbjct: 166 VARRNPFVFAPTLLTVAVHFEEVAKSCCEEQNKVNC----LQTRAIPVTQYLKAFSSYQK 221

Query: 298 DCCQEKTAMDVFVCTYFMPAAQLPELPDVE----------LPTNKDVCDPGNTKVMDKYT 347
             C         V  +   A    + P +E          + +N D C  G+     + T
Sbjct: 222 HVCGALLKFGTKVVHFIYIAILSQKFPKIEFKELISLVEDVSSNYDGCCEGDVVQCIRDT 281

Query: 348 FELSRRTHLPEVFLSKVLEPTLKSLGECCDV---EDSTTCFNAKGPLLKKELS----SFI 400
            ++       +  +S  ++       ECC+    E      N+      K+LS     F 
Sbjct: 282 SKVMNHICSKQDSISSKIK-------ECCEKKIPERGQCIINSNKDDRPKDLSLREGKFT 334

Query: 401 DKGQELCADYSENTFTEYKKKLAERLKAKLPDATPTELAKLVNKHSDFASNCCSINSPP 459
           D  + +C +   +  T + K   E  + + PD +  EL ++V  + D   NCC+  +PP
Sbjct: 335 DS-ENVCQERDADPDTFFAKFTFEYSR-RHPDLSIPELLRIVQIYKDLLRNCCNTENPP 391


>gi|4501989 alpha-fetoprotein precursor [Homo sapiens]
          Length = 609

 Score =  106 bits (264), Expect = 5e-23
 Identities = 98/481 (20%), Positives = 195/481 (40%), Gaps = 25/481 (5%)

Query: 5   LVLLLAVAFGHALERGRDYEKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLV 64
           L+ LL       L R  +Y    +   +    +     L+ + +++     T+++VS++V
Sbjct: 9   LIFLLNFTESRTLHRN-EYGIASILDSYQCTAEISLADLATIFFAQFVQEATYKEVSKMV 67

Query: 65  KEVVSLTEACCAEGADPDCYDTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLC-M 123
           K+ ++  E    +     C + +  A   + C        + G ++CC++    R  C +
Sbjct: 68  KDALTAIEKPTGDEQSSGCLENQLPAFLEELCHEKEILEKY-GHSDCCSQSEEGRHNCFL 126

Query: 124 AALKHQPQEFPTYVEPTNDEICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYL 183
           A  K  P   P +  P     CEA+ +D + + N+F++E +  +       ++ +   Y 
Sbjct: 127 AHKKPTPASIPLFQVPEPVTSCEAYEEDRETFMNKFIYEIARRHPFLYAPTILLWAARYD 186

Query: 184 SMVGSCCTSASPTVCF-LKERLQLKHLSLLTTLSNRVCSQYAAYGEKKSRLSNLIKLAQK 242
            ++ SCC + +   CF  K     K L   + L+   C+    +G +  +   + KL+QK
Sbjct: 187 KIIPSCCKAENAVECFQTKAATVTKELRESSLLNQHACAVMKNFGTRTFQAITVTKLSQK 246

Query: 243 VPTADLEDVLPLAEDITNILSKCCESASEDCMAKELPEHTVKLCDNLSTKNSKFEDCCQE 302
               +  ++  L  D+ ++   CC     DC+ ++  +    +C    T ++K  +CC +
Sbjct: 247 FTKVNFTEIQKLVLDVAHVHEHCCRGDVLDCL-QDGEKIMSYICSQQDTLSNKITECC-K 304

Query: 303 KTAMDVFVCTYFMPAAQLPELPDVELPTNKDVCD-------PGNTKV-MDKYTFELSRR- 353
            T ++   C       + PE     L  N+ + D        G   + +  +  E SRR 
Sbjct: 305 LTTLERGQCIIHAENDEKPEGLSPNL--NRFLGDRDFNQFSSGEKNIFLASFVHEYSRRH 362

Query: 354 THLPEVFLSKVLEPTLKSLGECCDVEDSTTCFNAKGPLLKKELSSFIDKGQEL----CAD 409
             L    + +V +   + L +C   E+   C   KG   ++EL  +I + Q L    C  
Sbjct: 363 PQLAVSVILRVAKGYQELLEKCFQTENPLEC-QDKG---EEELQKYIQESQALAKRSCGL 418

Query: 410 YSENTFTEYKKKLAERLKAKLPDATPTELAKLVNKHSDFASNCCSINSPPLYCDSEIDAE 469
           + +      +         K P  T +EL  +  K +  A+ CC ++   L    E  A+
Sbjct: 419 FQKLGEYYLQNAFLVAYTKKAPQLTSSELMAITRKMAATAATCCQLSEDKLLACGEGAAD 478

Query: 470 L 470
           +
Sbjct: 479 I 479



 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 80/386 (20%), Positives = 150/386 (38%), Gaps = 32/386 (8%)

Query: 29  CKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGADPDCYDTRT 88
           C    + G   F ++++   S+KF    F ++ +LV +V  + E CC  G   DC     
Sbjct: 224 CAVMKNFGTRTFQAITVTKLSQKFTKVNFTEIQKLVLDVAHVHEHCC-RGDVLDCLQDGE 282

Query: 89  SALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQPQEFPTYVEPT-----NDE 143
             +S    + ++   +     ECC    LER  C+  +  +  E P  + P       D 
Sbjct: 283 KIMSYICSQQDT---LSNKITECCKLTTLERGQCI--IHAENDEKPEGLSPNLNRFLGDR 337

Query: 144 ICEAFRKDPKE-YANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLKE 202
               F    K  +   F+ EYS  + Q  +S+++   K Y  ++  C  + +P  C  K 
Sbjct: 338 DFNQFSSGEKNIFLASFVHEYSRRHPQLAVSVILRVAKGYQELLEKCFQTENPLECQDKG 397

Query: 203 RLQL-KHLSLLTTLSNRVCSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDITNI 261
             +L K++     L+ R C  +   GE   + + L+   +K P     +++ +   +   
Sbjct: 398 EEELQKYIQESQALAKRSCGLFQKLGEYYLQNAFLVAYTKKAPQLTSSELMAITRKMAAT 457

Query: 262 LSKCCESASEDCMAKELPEHTV---KLC--DNLSTKNSKFEDCCQEKTA------MDVFV 310
            + CC+ + +  +A       +    LC    ++  N     CC    A        + V
Sbjct: 458 AATCCQLSEDKLLACGEGAADIIIGHLCIRHEMTPVNPGVGQCCTSSYANRRPCFSSLVV 517

Query: 311 CTYFMPAAQLPELPDVELPTNKDVCDPGNTKVMD-KYTFELS---RRTHLPEVFLSKVLE 366
              ++P    P   D +   +KD+C      +   K  F ++   ++  + E  L  V+ 
Sbjct: 518 DETYVP----PAFSDDKFIFHKDLCQAQGVALQTMKQEFLINLVKQKPQITEEQLEAVIA 573

Query: 367 PTLKSLGECCDVEDSTTCFNAKGPLL 392
                L +CC  ++   CF  +G  L
Sbjct: 574 DFSGLLEKCCQGQEQEVCFAEEGQKL 599


>gi|4826694 integral membrane protein DGCR2 [Homo sapiens]
          Length = 550

 Score = 32.3 bits (72), Expect = 0.96
 Identities = 17/43 (39%), Positives = 23/43 (53%), Gaps = 12/43 (27%)

Query: 112 CTKEGLERKLCMAALKHQPQEFPTYVEPTNDEICEAFRKDPKE 154
           CT  G E ++C+AAL  +PQ             C+ +RKDPKE
Sbjct: 296 CTCHGGEPEMCVAALCERPQG------------CQQYRKDPKE 326


>gi|130980075 centromere protein J [Homo sapiens]
          Length = 1338

 Score = 32.3 bits (72), Expect = 0.96
 Identities = 37/151 (24%), Positives = 55/151 (36%), Gaps = 15/151 (9%)

Query: 89  SALSAKSCESNSPFPVHPGTAEC-----CTKEGLERKLCMAALKHQPQEFPTYVEPTNDE 143
           S L  +  ESN+P+      +E      C K+G +   C +A  HQ +    ++     E
Sbjct: 73  SLLEEQKLESNNPYKPQSDKSETHTAFPCIKKGPQVAACHSAPGHQEENKNDFIPDLASE 132

Query: 144 ICEAFRKDP-------KEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPT 196
             E   KDP        +   Q   E         L  L+   +  L+MV   CT   P 
Sbjct: 133 FKEGAYKDPLFKKLEQLKEVQQKKQEQLKRQQLEQLQRLMEEQEKLLTMVSGQCT--LPG 190

Query: 197 VCFLKERLQLKHLSL-LTTLSNRVCSQYAAY 226
           +  L +    KH S   TT   R    + +Y
Sbjct: 191 LSLLPDDQSQKHRSPGNTTTGERATCCFPSY 221


>gi|191252801 WDFY family member 4 [Homo sapiens]
          Length = 3184

 Score = 30.0 bits (66), Expect = 4.8
 Identities = 17/67 (25%), Positives = 31/67 (46%), Gaps = 8/67 (11%)

Query: 188 SCCTSASPTVCFLKERLQLKHLSLLTTLSNRVCSQYAAYGEKKSRLSNLIKLAQKVPTAD 247
           SCC    PT C L+   + ++LS++  L    C + +        L NL +L   +P  +
Sbjct: 232 SCCFWKEPTFCVLRAISKAQNLSIIQYLQATDCVRLS--------LQNLSRLTDTLPAPE 283

Query: 248 LEDVLPL 254
           + + + L
Sbjct: 284 VSEAVSL 290


>gi|26190614 rhotekin 2 [Homo sapiens]
          Length = 609

 Score = 30.0 bits (66), Expect = 4.8
 Identities = 17/68 (25%), Positives = 35/68 (51%), Gaps = 7/68 (10%)

Query: 380 DSTTCFNAKGPLLKKELSSFIDKGQELCADYSENTFTEYKKKLAERLKAKLPDATPTELA 439
           ++ T FN  GP  + ++  +       C +  E++ T   KKLA++LK  +  AT  +++
Sbjct: 158 ENVTIFNEAGPDFQIKVEVY-----SCCTE--ESSITNTPKKLAKKLKTSISKATGKKIS 210

Query: 440 KLVNKHSD 447
            ++ +  D
Sbjct: 211 SVLQEEDD 218


>gi|169207319 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 828

 Score = 29.6 bits (65), Expect = 6.2
 Identities = 17/65 (26%), Positives = 31/65 (47%)

Query: 377 DVEDSTTCFNAKGPLLKKELSSFIDKGQELCADYSENTFTEYKKKLAERLKAKLPDATPT 436
           D+     C      L++KE + ++ + QEL A  +E   T   K++    K K  D   T
Sbjct: 208 DIALQKKCIQEAEELMEKERAEYLIRKQELTAQINEFENTREVKRMETYQKKKELDKLQT 267

Query: 437 ELAKL 441
           +++K+
Sbjct: 268 KMSKI 272


>gi|169207756 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 828

 Score = 29.6 bits (65), Expect = 6.2
 Identities = 17/65 (26%), Positives = 31/65 (47%)

Query: 377 DVEDSTTCFNAKGPLLKKELSSFIDKGQELCADYSENTFTEYKKKLAERLKAKLPDATPT 436
           D+     C      L++KE + ++ + QEL A  +E   T   K++    K K  D   T
Sbjct: 208 DIALQKKCIQEAEELMEKERAEYLIRKQELTAQINEFENTREVKRMETYQKKKELDKLQT 267

Query: 437 ELAKL 441
           +++K+
Sbjct: 268 KMSKI 272


>gi|169207046 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 828

 Score = 29.6 bits (65), Expect = 6.2
 Identities = 17/65 (26%), Positives = 31/65 (47%)

Query: 377 DVEDSTTCFNAKGPLLKKELSSFIDKGQELCADYSENTFTEYKKKLAERLKAKLPDATPT 436
           D+     C      L++KE + ++ + QEL A  +E   T   K++    K K  D   T
Sbjct: 208 DIALQKKCIQEAEELMEKERAEYLIRKQELTAQINEFENTREVKRMETYQKKKELDKLQT 267

Query: 437 ELAKL 441
           +++K+
Sbjct: 268 KMSKI 272


>gi|33286418 pyruvate kinase, muscle isoform M2 [Homo sapiens]
          Length = 531

 Score = 29.3 bits (64), Expect = 8.1
 Identities = 22/72 (30%), Positives = 32/72 (44%), Gaps = 3/72 (4%)

Query: 52  FPSGTFEQVSQLVKEVVSLTEACCAEGADPDCYDTRTSALSAKSCESNSPFPVHPGTAEC 111
           F  GT E  ++ +K V + TE+  +   DP  Y     AL  K  E  +      GTAE 
Sbjct: 76  FSHGTHEYHAETIKNVRTATESFAS---DPILYRPVAVALDTKGPEIRTGLIKGSGTAEV 132

Query: 112 CTKEGLERKLCM 123
             K+G   K+ +
Sbjct: 133 ELKKGATLKITL 144


>gi|33286422 pyruvate kinase, muscle isoform M1 [Homo sapiens]
          Length = 531

 Score = 29.3 bits (64), Expect = 8.1
 Identities = 22/72 (30%), Positives = 32/72 (44%), Gaps = 3/72 (4%)

Query: 52  FPSGTFEQVSQLVKEVVSLTEACCAEGADPDCYDTRTSALSAKSCESNSPFPVHPGTAEC 111
           F  GT E  ++ +K V + TE+  +   DP  Y     AL  K  E  +      GTAE 
Sbjct: 76  FSHGTHEYHAETIKNVRTATESFAS---DPILYRPVAVALDTKGPEIRTGLIKGSGTAEV 132

Query: 112 CTKEGLERKLCM 123
             K+G   K+ +
Sbjct: 133 ELKKGATLKITL 144


>gi|33286420 pyruvate kinase, muscle isoform M1 [Homo sapiens]
          Length = 531

 Score = 29.3 bits (64), Expect = 8.1
 Identities = 22/72 (30%), Positives = 32/72 (44%), Gaps = 3/72 (4%)

Query: 52  FPSGTFEQVSQLVKEVVSLTEACCAEGADPDCYDTRTSALSAKSCESNSPFPVHPGTAEC 111
           F  GT E  ++ +K V + TE+  +   DP  Y     AL  K  E  +      GTAE 
Sbjct: 76  FSHGTHEYHAETIKNVRTATESFAS---DPILYRPVAVALDTKGPEIRTGLIKGSGTAEV 132

Query: 112 CTKEGLERKLCM 123
             K+G   K+ +
Sbjct: 133 ELKKGATLKITL 144


>gi|169218111 PREDICTED: similar to pyruvate kinase, muscle [Homo
           sapiens]
          Length = 364

 Score = 29.3 bits (64), Expect = 8.1
 Identities = 22/72 (30%), Positives = 32/72 (44%), Gaps = 3/72 (4%)

Query: 52  FPSGTFEQVSQLVKEVVSLTEACCAEGADPDCYDTRTSALSAKSCESNSPFPVHPGTAEC 111
           F  GT E  ++ +K V + TE+  +   DP  Y     AL  K  E  +      GTAE 
Sbjct: 76  FSHGTHEYHAETIKNVRTATESFAS---DPILYRPVAVALDTKGPEIRTGLIKGSGTAEV 132

Query: 112 CTKEGLERKLCM 123
             K+G   K+ +
Sbjct: 133 ELKKGATLKITL 144


>gi|122937343 platelet endothelial aggregation receptor 1 [Homo
           sapiens]
          Length = 1037

 Score = 29.3 bits (64), Expect = 8.1
 Identities = 20/68 (29%), Positives = 24/68 (35%), Gaps = 4/68 (5%)

Query: 55  GTFEQVSQLVKEVVSLTEACCAEGADPDCYDTRTSALSAKSCESNSPFPVHPGTAECCTK 114
           G  +  S L +     T   CA    PD Y    SA     C   +     P   EC  K
Sbjct: 414 GVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSA----RCSCENAIACSPIDGECVCK 469

Query: 115 EGLERKLC 122
           EG +R  C
Sbjct: 470 EGWQRGNC 477


>gi|116686120 periaxin isoform 2 [Homo sapiens]
          Length = 1461

 Score = 29.3 bits (64), Expect = 8.1
 Identities = 21/60 (35%), Positives = 33/60 (55%), Gaps = 5/60 (8%)

Query: 315 MPAAQLPELPDVELPTNKDVCDPGNTKVMDKYTFELSRRTHLPEVFLSKVLEPTLKSLGE 374
           +P  QLP++P+++LP  K + +    KV +    ++    HLPEV L KV E  L  + E
Sbjct: 618 LPEVQLPKVPEMKLPEMK-LPEVKLPKVPEMAVPDV----HLPEVQLPKVPEMKLPKMPE 672


>gi|110347437 latent transforming growth factor beta binding protein 4
            isoform c [Homo sapiens]
          Length = 1557

 Score = 29.3 bits (64), Expect = 8.1
 Identities = 25/127 (19%), Positives = 47/127 (37%), Gaps = 20/127 (15%)

Query: 286  CDNLSTKNSKFEDCCQEKTAMDVFVCTY---FMPAAQLPELPDVELPTNKDVCDPGNTKV 342
            CDN+  +N  +++CC          CT    +    ++ + P  E    + +C  G   +
Sbjct: 1126 CDNILARNVTWQECC----------CTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYL 1175

Query: 343  MDKYTFELSRRTHLPEVFLSKVLEPTLKSLGECCDVEDSTTCFNAKGPLLKKELSSFIDK 402
                   L R     ++F  +V +      G C +     +C+ + G     +    ID 
Sbjct: 1176 APSGDLSLRRDVDECQLFRDQVCKS-----GVCVNTAPGYSCYCSNGYYYHTQRLECIDN 1230

Query: 403  GQELCAD 409
             +  CAD
Sbjct: 1231 DE--CAD 1235


>gi|110347412 latent transforming growth factor beta binding protein 4
            isoform b [Homo sapiens]
          Length = 1587

 Score = 29.3 bits (64), Expect = 8.1
 Identities = 25/127 (19%), Positives = 47/127 (37%), Gaps = 20/127 (15%)

Query: 286  CDNLSTKNSKFEDCCQEKTAMDVFVCTY---FMPAAQLPELPDVELPTNKDVCDPGNTKV 342
            CDN+  +N  +++CC          CT    +    ++ + P  E    + +C  G   +
Sbjct: 1156 CDNILARNVTWQECC----------CTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYL 1205

Query: 343  MDKYTFELSRRTHLPEVFLSKVLEPTLKSLGECCDVEDSTTCFNAKGPLLKKELSSFIDK 402
                   L R     ++F  +V +      G C +     +C+ + G     +    ID 
Sbjct: 1206 APSGDLSLRRDVDECQLFRDQVCKS-----GVCVNTAPGYSCYCSNGYYYHTQRLECIDN 1260

Query: 403  GQELCAD 409
             +  CAD
Sbjct: 1261 DE--CAD 1265


>gi|110347431 latent transforming growth factor beta binding protein 4
            isoform a [Homo sapiens]
          Length = 1624

 Score = 29.3 bits (64), Expect = 8.1
 Identities = 25/127 (19%), Positives = 47/127 (37%), Gaps = 20/127 (15%)

Query: 286  CDNLSTKNSKFEDCCQEKTAMDVFVCTY---FMPAAQLPELPDVELPTNKDVCDPGNTKV 342
            CDN+  +N  +++CC          CT    +    ++ + P  E    + +C  G   +
Sbjct: 1193 CDNILARNVTWQECC----------CTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYL 1242

Query: 343  MDKYTFELSRRTHLPEVFLSKVLEPTLKSLGECCDVEDSTTCFNAKGPLLKKELSSFIDK 402
                   L R     ++F  +V +      G C +     +C+ + G     +    ID 
Sbjct: 1243 APSGDLSLRRDVDECQLFRDQVCKS-----GVCVNTAPGYSCYCSNGYYYHTQRLECIDN 1297

Query: 403  GQELCAD 409
             +  CAD
Sbjct: 1298 DE--CAD 1302


>gi|14589929 protocadherin 18 precursor [Homo sapiens]
          Length = 1135

 Score = 29.3 bits (64), Expect = 8.1
 Identities = 25/98 (25%), Positives = 40/98 (40%), Gaps = 17/98 (17%)

Query: 314  FMPAAQLPELPDVELPTN--KDVCDP-------------GNTKVMDKYTFELSRRTHLPE 358
            F+P  + P  P  + P    +D   P             G     D+ T + S  + L E
Sbjct: 948  FIPGEEFPTQPQQQHPHQSLEDDAQPADSGEKKKSFSTFGKDSPNDEDTGDTSTSSLLSE 1007

Query: 359  V--FLSKVLEPTLKSLGECCDVEDSTTCFNAKGPLLKK 394
            +     ++L P+L +  EC +V+ S +    KGPL  K
Sbjct: 1008 MSSVFQRLLPPSLDTYSECSEVDRSNSLERRKGPLPAK 1045


>gi|30794372 polybromo 1 isoform 1 [Homo sapiens]
          Length = 1602

 Score = 29.3 bits (64), Expect = 8.1
 Identities = 17/58 (29%), Positives = 32/58 (55%), Gaps = 7/58 (12%)

Query: 241  QKVPTADLEDVLPLAEDITNILSKCCESASED---CMAKELPEHTVKLCDNLSTKNSK 295
            ++V  ++LE+  P+    T IL KC   + +D   C   E+PE+ + LC++   ++ K
Sbjct: 1181 KEVFLSNLEETCPM----TCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDK 1234


>gi|93102371 polybromo 1 isoform 2 [Homo sapiens]
          Length = 1582

 Score = 29.3 bits (64), Expect = 8.1
 Identities = 17/58 (29%), Positives = 32/58 (55%), Gaps = 7/58 (12%)

Query: 241  QKVPTADLEDVLPLAEDITNILSKCCESASED---CMAKELPEHTVKLCDNLSTKNSK 295
            ++V  ++LE+  P+    T IL KC   + +D   C   E+PE+ + LC++   ++ K
Sbjct: 1188 KEVFLSNLEETCPM----TCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDK 1241


>gi|41281917 polybromo 1 isoform 4 [Homo sapiens]
          Length = 1582

 Score = 29.3 bits (64), Expect = 8.1
 Identities = 17/58 (29%), Positives = 32/58 (55%), Gaps = 7/58 (12%)

Query: 241  QKVPTADLEDVLPLAEDITNILSKCCESASED---CMAKELPEHTVKLCDNLSTKNSK 295
            ++V  ++LE+  P+    T IL KC   + +D   C   E+PE+ + LC++   ++ K
Sbjct: 1213 KEVFLSNLEETCPM----TCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDK 1266


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.131    0.391 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,801,876
Number of Sequences: 37866
Number of extensions: 852916
Number of successful extensions: 2311
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 2238
Number of HSP's gapped (non-prelim): 52
length of query: 474
length of database: 18,247,518
effective HSP length: 106
effective length of query: 368
effective length of database: 14,233,722
effective search space: 5238009696
effective search space used: 5238009696
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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