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Search of human proteins with 32313610
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|32313610 ubiquitin specific protease 18 [Homo sapiens]
(372 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|32313610 ubiquitin specific protease 18 [Homo sapiens] 767 0.0
gi|239746654 PREDICTED: ubiquitin specific protease 41 [Homo sap... 629 e-180
gi|239757637 PREDICTED: ubiquitin specific peptidase 41 [Homo sa... 627 e-180
gi|169215723 PREDICTED: ubiquitin specific peptidase 41 [Homo sa... 588 e-168
gi|71774197 ubiquitin specific protease 47 [Homo sapiens] 144 1e-34
gi|76257392 ubiquitin specific protease 48 isoform b [Homo sapiens] 99 6e-21
gi|52630449 ubiquitin specific protease 48 isoform a [Homo sapiens] 99 6e-21
gi|149192845 ubiquitin specific protease 24 [Homo sapiens] 96 7e-20
gi|150378533 ubiquitin specific peptidase 7 [Homo sapiens] 92 6e-19
gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens] 91 2e-18
gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens] 91 2e-18
gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens] 91 2e-18
gi|110347427 ubiquitin specific protease 34 [Homo sapiens] 90 3e-18
gi|183396780 ubiquitin specific protease 20 [Homo sapiens] 87 3e-17
gi|183397136 ubiquitin specific protease 20 [Homo sapiens] 87 3e-17
gi|183397134 ubiquitin specific protease 20 [Homo sapiens] 87 3e-17
gi|41152235 ubiquitin specific protease 51 [Homo sapiens] 85 9e-17
gi|28565285 ubiquitin specific peptidase 2 isoform b [Homo sapiens] 85 1e-16
gi|188528692 ubiquitin specific peptidase 2 isoform a [Homo sapi... 85 1e-16
gi|42516561 ubiquitin specific protease 33 isoform 3 [Homo sapiens] 83 5e-16
gi|42516567 ubiquitin specific protease 33 isoform 1 [Homo sapiens] 83 5e-16
gi|42516565 ubiquitin specific protease 33 isoform 2 [Homo sapiens] 83 5e-16
gi|223005906 X-linked ubiquitin thioesterase 27 [Homo sapiens] 79 5e-15
gi|41055953 ubiquitin thioesterase 40 [Homo sapiens] 79 5e-15
gi|45267835 ubiquitin specific protease 50 [Homo sapiens] 78 1e-14
gi|14149627 ubiquitin specific peptidase 15 [Homo sapiens] 77 2e-14
gi|120587027 ubiquitin specific peptidase 31 [Homo sapiens] 77 2e-14
gi|40795665 ubiquitin specific protease 4 isoform a [Homo sapiens] 75 1e-13
gi|40795667 ubiquitin specific protease 4 isoform b [Homo sapiens] 75 1e-13
gi|150010639 ubiquitin thiolesterase 22 [Homo sapiens] 74 2e-13
>gi|32313610 ubiquitin specific protease 18 [Homo sapiens]
Length = 372
Score = 767 bits (1980), Expect = 0.0
Identities = 372/372 (100%), Positives = 372/372 (100%)
Query: 1 MSKAFGLLRQICQSILAESSQSPADLEEKKEEDSNMKREQPRERPRAWDYPHGLVGLHNI 60
MSKAFGLLRQICQSILAESSQSPADLEEKKEEDSNMKREQPRERPRAWDYPHGLVGLHNI
Sbjct: 1 MSKAFGLLRQICQSILAESSQSPADLEEKKEEDSNMKREQPRERPRAWDYPHGLVGLHNI 60
Query: 61 GQTCCLNSLIQVFVMNVDFTRILKRITVPRGADEQRRSVPFQMLLLLEKMQDSRQKAVRP 120
GQTCCLNSLIQVFVMNVDFTRILKRITVPRGADEQRRSVPFQMLLLLEKMQDSRQKAVRP
Sbjct: 61 GQTCCLNSLIQVFVMNVDFTRILKRITVPRGADEQRRSVPFQMLLLLEKMQDSRQKAVRP 120
Query: 121 LELAYCLQKCNVPLFVQHDAAQLYLKLWNLIKDQITDVHLVERLQALYTIRVKDSLICVD 180
LELAYCLQKCNVPLFVQHDAAQLYLKLWNLIKDQITDVHLVERLQALYTIRVKDSLICVD
Sbjct: 121 LELAYCLQKCNVPLFVQHDAAQLYLKLWNLIKDQITDVHLVERLQALYTIRVKDSLICVD 180
Query: 181 CAMESSRNSSMLTLPLSLFDVDSKPLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGK 240
CAMESSRNSSMLTLPLSLFDVDSKPLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGK
Sbjct: 181 CAMESSRNSSMLTLPLSLFDVDSKPLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGK 240
Query: 241 QVLKLTHLPQTLTIHLMRFSIRNSQTRKICHSLYFPQSLDFSQILPMKRESCDAEEQSGG 300
QVLKLTHLPQTLTIHLMRFSIRNSQTRKICHSLYFPQSLDFSQILPMKRESCDAEEQSGG
Sbjct: 241 QVLKLTHLPQTLTIHLMRFSIRNSQTRKICHSLYFPQSLDFSQILPMKRESCDAEEQSGG 300
Query: 301 QYELFAVIAHVGMADSGHYCVYIRNAVDGKWFCFNDSNICLVSWEDIQCTYGNPNYHWQE 360
QYELFAVIAHVGMADSGHYCVYIRNAVDGKWFCFNDSNICLVSWEDIQCTYGNPNYHWQE
Sbjct: 301 QYELFAVIAHVGMADSGHYCVYIRNAVDGKWFCFNDSNICLVSWEDIQCTYGNPNYHWQE 360
Query: 361 TAYLLVYMKMEC 372
TAYLLVYMKMEC
Sbjct: 361 TAYLLVYMKMEC 372
>gi|239746654 PREDICTED: ubiquitin specific protease 41 [Homo
sapiens]
Length = 347
Score = 629 bits (1622), Expect = e-180
Identities = 303/314 (96%), Positives = 306/314 (97%)
Query: 45 PRAWDYPHGLVGLHNIGQTCCLNSLIQVFVMNVDFTRILKRITVPRGADEQRRSVPFQML 104
PR+WDY HGLVGLHNIGQTCCLNSLIQVFVMNVDF RILKRITVPRGADEQRRSVPFQML
Sbjct: 34 PRSWDYRHGLVGLHNIGQTCCLNSLIQVFVMNVDFARILKRITVPRGADEQRRSVPFQML 93
Query: 105 LLLEKMQDSRQKAVRPLELAYCLQKCNVPLFVQHDAAQLYLKLWNLIKDQITDVHLVERL 164
LLLEKMQDSRQKAV PLELAYCLQK NVPLFVQHDAAQLYLKLWNLIKDQI DVHLVERL
Sbjct: 94 LLLEKMQDSRQKAVWPLELAYCLQKYNVPLFVQHDAAQLYLKLWNLIKDQIADVHLVERL 153
Query: 165 QALYTIRVKDSLICVDCAMESSRNSSMLTLPLSLFDVDSKPLKTLEDALHCFFQPRELSS 224
QALY IR+KDSLIC+DCAMESSRNSSMLTL LS FDVDSKPLKTLEDALHCFFQPRELSS
Sbjct: 154 QALYMIRMKDSLICLDCAMESSRNSSMLTLRLSFFDVDSKPLKTLEDALHCFFQPRELSS 213
Query: 225 KSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTRKICHSLYFPQSLDFSQI 284
KSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTRKICHSLYFPQSLDFSQI
Sbjct: 214 KSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTRKICHSLYFPQSLDFSQI 273
Query: 285 LPMKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIRNAVDGKWFCFNDSNICLVSW 344
LPMKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIRNAVDGKWFCFNDSNICLVSW
Sbjct: 274 LPMKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIRNAVDGKWFCFNDSNICLVSW 333
Query: 345 EDIQCTYGNPNYHW 358
EDIQCTYGNPNYHW
Sbjct: 334 EDIQCTYGNPNYHW 347
>gi|239757637 PREDICTED: ubiquitin specific peptidase 41 [Homo
sapiens]
Length = 344
Score = 627 bits (1618), Expect = e-180
Identities = 307/327 (93%), Positives = 312/327 (95%), Gaps = 1/327 (0%)
Query: 36 MKREQPRERPR-AWDYPHGLVGLHNIGQTCCLNSLIQVFVMNVDFTRILKRITVPRGADE 94
MK+ Q P+ +WDY HGLVGLHNIGQTCCLNSLIQVFVMNVDF RILKRITVPRGADE
Sbjct: 1 MKQLQLFSVPKISWDYRHGLVGLHNIGQTCCLNSLIQVFVMNVDFARILKRITVPRGADE 60
Query: 95 QRRSVPFQMLLLLEKMQDSRQKAVRPLELAYCLQKCNVPLFVQHDAAQLYLKLWNLIKDQ 154
QRRSVPFQMLLLLEKMQDSRQKAV PLELAYCLQK NVPLFVQHDAAQLYLKLWNLIKDQ
Sbjct: 61 QRRSVPFQMLLLLEKMQDSRQKAVWPLELAYCLQKYNVPLFVQHDAAQLYLKLWNLIKDQ 120
Query: 155 ITDVHLVERLQALYTIRVKDSLICVDCAMESSRNSSMLTLPLSLFDVDSKPLKTLEDALH 214
I DVHLVERLQALY IRVKDSLIC+DCAMESSRNSSMLTL LS FDVDSKPLKTLEDALH
Sbjct: 121 IADVHLVERLQALYMIRVKDSLICLDCAMESSRNSSMLTLRLSFFDVDSKPLKTLEDALH 180
Query: 215 CFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTRKICHSLY 274
CFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTRKICHSLY
Sbjct: 181 CFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTRKICHSLY 240
Query: 275 FPQSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIRNAVDGKWFCF 334
FPQSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIR+AVDGKWFCF
Sbjct: 241 FPQSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIRSAVDGKWFCF 300
Query: 335 NDSNICLVSWEDIQCTYGNPNYHWQET 361
NDSNICLVSWEDIQCTYGNPNYHW ET
Sbjct: 301 NDSNICLVSWEDIQCTYGNPNYHWXET 327
>gi|169215723 PREDICTED: ubiquitin specific peptidase 41 [Homo
sapiens]
Length = 346
Score = 588 bits (1515), Expect = e-168
Identities = 287/298 (96%), Positives = 290/298 (97%)
Query: 45 PRAWDYPHGLVGLHNIGQTCCLNSLIQVFVMNVDFTRILKRITVPRGADEQRRSVPFQML 104
PR+WDY HGLVGLHNIGQTCCLNSLIQVFVMNVDF RILKRITVPRGADEQRRSVPFQML
Sbjct: 34 PRSWDYRHGLVGLHNIGQTCCLNSLIQVFVMNVDFARILKRITVPRGADEQRRSVPFQML 93
Query: 105 LLLEKMQDSRQKAVRPLELAYCLQKCNVPLFVQHDAAQLYLKLWNLIKDQITDVHLVERL 164
LLLEKMQDSRQKAV PLELAYCLQK NVPLFVQHDAAQLYLKLWNLIKDQI DVHLVERL
Sbjct: 94 LLLEKMQDSRQKAVWPLELAYCLQKYNVPLFVQHDAAQLYLKLWNLIKDQIADVHLVERL 153
Query: 165 QALYTIRVKDSLICVDCAMESSRNSSMLTLPLSLFDVDSKPLKTLEDALHCFFQPRELSS 224
QALY IR+KDSLIC+DCAMESSRNSSMLTL LS FDVDSKPLKTLEDALHCFFQPRELSS
Sbjct: 154 QALYMIRMKDSLICLDCAMESSRNSSMLTLRLSFFDVDSKPLKTLEDALHCFFQPRELSS 213
Query: 225 KSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTRKICHSLYFPQSLDFSQI 284
KSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTRKICHSLYFPQSLDFSQI
Sbjct: 214 KSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTRKICHSLYFPQSLDFSQI 273
Query: 285 LPMKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIRNAVDGKWFCFNDSNICLV 342
LPMKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIRNAVDGKWFCFNDSNICLV
Sbjct: 274 LPMKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIRNAVDGKWFCFNDSNICLV 331
>gi|71774197 ubiquitin specific protease 47 [Homo sapiens]
Length = 1287
Score = 144 bits (364), Expect = 1e-34
Identities = 96/376 (25%), Positives = 166/376 (44%), Gaps = 61/376 (16%)
Query: 53 GLVGLHNIGQTCCLNSLIQVFVMNVDFTRILKRITVPRGADEQRRSVPFQMLLLLEKMQD 112
G VGL N TC LNSL+Q M +F L + ++ S+P+Q+ L +Q
Sbjct: 98 GYVGLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFEESEEDPVTSIPYQLQRLFVLLQT 157
Query: 113 SRQKAVRPLELAYCLQKCNVPLFVQHDAAQLYLKLWNLIKDQITDVHLVERLQALYTIRV 172
S+++A+ ++ + + QHD +L +++ ++ + + + LY ++
Sbjct: 158 SKKRAIETTDVTRSFGWDSSEAWQQHDVQELCRVMFDALEQKWKQTEQADLINELYQGKL 217
Query: 173 KDSLICVDCAMESSRNSSMLTLPLSLFDV-DSKPLKTLEDALHCFFQPRELSSKSKCFCE 231
KD + C++C E R + L +PL + S+ ++E+ALH F QP L ++ FCE
Sbjct: 218 KDYVRCLECGYEGWRIDTYLDIPLVIRPYGSSQAFASVEEALHAFIQPEILDGPNQYFCE 277
Query: 232 NCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTR--KICHSLYFPQSLDFSQILPMKR 289
C KK ++ L+ H P LT+ L RF + K+ + FP+ LD S + ++
Sbjct: 278 RCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLNDRMTFPEELDMSTFIDVED 337
Query: 290 E-----------------SCDAEEQSGG-------------------------------- 300
E SC +++ S
Sbjct: 338 EKSPQTESCTDSGAENEGSCHSDQMSNDFSNDDGVDEGICLETNSGTEKISKSGLEKNSL 397
Query: 301 QYELFAVIAHVGMADSGHYCVYIRNAVDGKWFCFNDSNICLVSWEDIQCTYGNPN----- 355
YELF+V+ H G A GHY I++ D +W+ FND ++ ++ EDI+ T+G +
Sbjct: 398 IYELFSVMVHSGSAAGGHYYACIKSFSDEQWYSFNDQHVSRITQEDIKKTHGGSSGSRGY 457
Query: 356 ----YHWQETAYLLVY 367
+ AY+L+Y
Sbjct: 458 YSSAFASSTNAYMLIY 473
>gi|76257392 ubiquitin specific protease 48 isoform b [Homo sapiens]
Length = 485
Score = 99.0 bits (245), Expect = 6e-21
Identities = 90/354 (25%), Positives = 151/354 (42%), Gaps = 59/354 (16%)
Query: 52 HGLVGLHNIGQTCCLNSLIQVFVMNVDFTRILKRIT-----------VPRGADEQRRSVP 100
+ VGL N+G TC +N+ +QV+ +N++ + L + D + +++
Sbjct: 86 NSFVGLTNLGATCYVNTFLQVWFLNLELRQALYLCPSTCSDYMLGDGIQEEKDYEPQTIC 145
Query: 101 FQMLLLLEKMQDSRQKAVRPLELAYCLQKCNVPLFVQHDAAQLYLKLWNLIKDQIT---- 156
+ L +Q+S ++ + P L + Q DA + +L++D ++
Sbjct: 146 EHLQYLFALLQNSNRRYIDPSGFVKAL---GLDTGQQQDAQEFSKLFMSLLEDTLSKQKN 202
Query: 157 -DVHLVERLQALYTIRVKDSLICVDCAMESSRNSSMLTLPLSLFDVDSKPLKTLEDALHC 215
DV + +Q + +C C ES S L L++ + K L D +
Sbjct: 203 PDVRNI--VQQQFCGEYAYVTVCNQCGRESKLLSKFYELELNI-----QGHKQLTDCISE 255
Query: 216 FFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTRKICHSLYF 275
F + +L ++ FCENC K + ++L LP TL + LMRF R+ H
Sbjct: 256 FLKEEKLEGDNRYFCENCQSKQNATRKIRLLSLPCTLNLQLMRFVF----DRQTGHKKKL 311
Query: 276 PQSLDFSQILPMKRESCDAEEQSGGQ--YELFAVIAHVGM-ADSGHYCVYIRNAVDGKWF 332
+ FS+IL M+ E GG YEL AV+ H G+ A SGHY ++++ G+W+
Sbjct: 312 NTYIGFSEILDME----PYVEHKGGSYVYELSAVLIHRGVSAYSGHYIAHVKDPQSGEWY 367
Query: 333 CFNDSNICLVSWEDIQ-------------------CTYGNPNYHWQETAYLLVY 367
FND +I + + +Q C G H AY+LVY
Sbjct: 368 KFNDEDIEKMEGKKLQLGIEEDLAEPSKSQTRKPKCGKGT---HCSRNAYMLVY 418
>gi|52630449 ubiquitin specific protease 48 isoform a [Homo sapiens]
Length = 1035
Score = 99.0 bits (245), Expect = 6e-21
Identities = 90/354 (25%), Positives = 151/354 (42%), Gaps = 59/354 (16%)
Query: 52 HGLVGLHNIGQTCCLNSLIQVFVMNVDFTRILKRIT-----------VPRGADEQRRSVP 100
+ VGL N+G TC +N+ +QV+ +N++ + L + D + +++
Sbjct: 86 NSFVGLTNLGATCYVNTFLQVWFLNLELRQALYLCPSTCSDYMLGDGIQEEKDYEPQTIC 145
Query: 101 FQMLLLLEKMQDSRQKAVRPLELAYCLQKCNVPLFVQHDAAQLYLKLWNLIKDQIT---- 156
+ L +Q+S ++ + P L + Q DA + +L++D ++
Sbjct: 146 EHLQYLFALLQNSNRRYIDPSGFVKAL---GLDTGQQQDAQEFSKLFMSLLEDTLSKQKN 202
Query: 157 -DVHLVERLQALYTIRVKDSLICVDCAMESSRNSSMLTLPLSLFDVDSKPLKTLEDALHC 215
DV + +Q + +C C ES S L L++ + K L D +
Sbjct: 203 PDVRNI--VQQQFCGEYAYVTVCNQCGRESKLLSKFYELELNI-----QGHKQLTDCISE 255
Query: 216 FFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTRKICHSLYF 275
F + +L ++ FCENC K + ++L LP TL + LMRF R+ H
Sbjct: 256 FLKEEKLEGDNRYFCENCQSKQNATRKIRLLSLPCTLNLQLMRFVF----DRQTGHKKKL 311
Query: 276 PQSLDFSQILPMKRESCDAEEQSGGQ--YELFAVIAHVGM-ADSGHYCVYIRNAVDGKWF 332
+ FS+IL M+ E GG YEL AV+ H G+ A SGHY ++++ G+W+
Sbjct: 312 NTYIGFSEILDME----PYVEHKGGSYVYELSAVLIHRGVSAYSGHYIAHVKDPQSGEWY 367
Query: 333 CFNDSNICLVSWEDIQ-------------------CTYGNPNYHWQETAYLLVY 367
FND +I + + +Q C G H AY+LVY
Sbjct: 368 KFNDEDIEKMEGKKLQLGIEEDLAEPSKSQTRKPKCGKGT---HCSRNAYMLVY 418
>gi|149192845 ubiquitin specific protease 24 [Homo sapiens]
Length = 2460
Score = 95.5 bits (236), Expect = 7e-20
Identities = 94/361 (26%), Positives = 150/361 (41%), Gaps = 45/361 (12%)
Query: 15 ILAESSQSPADLEEKKEEDSNMKREQPRERPRAWDY--------PHGLVGLHNIGQTCCL 66
+LA+SS P++L+ +E +M + + +DY G VGL N G TC +
Sbjct: 1483 MLADSS--PSNLQIIIKELLSMHHQPDPALTKEFDYLPPVDSRSSSGFVGLRNGGATCYM 1540
Query: 67 NSLIQVFVMNVDFTRILKRITVPRGADEQRRSVPFQMLLLLEKMQDSRQKAVRPLELAYC 126
N++ Q M L ++V D SV +Q+ L + +S+ + P
Sbjct: 1541 NAVFQQLYMQPGLPESL--LSVDDDTDNPDDSVFYQVQSLFGHLMESKLQYYVPENFWKI 1598
Query: 127 LQKCNVPLFV--QHDAAQLYLKLWNLIKDQITDVHLVERLQALYTIRVKDSLICVDCAME 184
+ N L+V Q DA + + L + + + + + + + + D IC DC
Sbjct: 1599 FKMWNKELYVREQQDAYEFFTSLIDQMDEYLKKMGRDQIFKNTFQGIYSDQKICKDCPHR 1658
Query: 185 SSRNSSMLTLPLSLFDVDSKPLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLK 244
R + + L L + S LE +L F + L + +CE C +K +
Sbjct: 1659 YEREEAFMALNLGVTSCQS-----LEISLDQFVRGEVLEGSNAYYCEKCKEKRITVKRTC 1713
Query: 245 LTHLPQTLTIHLMRFSI--RNSQTRKICHSLYFPQSLDFS--QILPMKRESCDAE----- 295
+ LP L IHLMRF + ++ K + FP L+ + M R+ +E
Sbjct: 1714 IKSLPSVLVIHLMRFGFDWESGRSIKYDEQIRFPWMLNMEPYTVSGMARQDSSSEVGENG 1773
Query: 296 ---EQSGG-----------QYELFAVIAHVGMADSGHYCVYI---RNAVDGKWFCFNDSN 338
+Q GG YEL VI H G A +GHY +I R GKW+ FND+
Sbjct: 1774 RSVDQGGGGSPRKKVALTENYELVGVIVHSGQAHAGHYYSFIKDRRGCGKGKWYKFNDTV 1833
Query: 339 I 339
I
Sbjct: 1834 I 1834
>gi|150378533 ubiquitin specific peptidase 7 [Homo sapiens]
Length = 1102
Score = 92.4 bits (228), Expect = 6e-19
Identities = 89/334 (26%), Positives = 144/334 (43%), Gaps = 28/334 (8%)
Query: 47 AWDYPH--GLVGLHNIGQTCCLNSLIQVFVMNVDFTRILKRIT--VPRGADEQRRSVPFQ 102
AWD G VGL N G TC +NSL+Q FT L++ +P D+ +SVP
Sbjct: 204 AWDSKKHTGYVGLKNQGATCYMNSLLQTLF----FTNQLRKAVYMMPTEGDDSSKSVPLA 259
Query: 103 MLLLLEKMQDSRQKAVRPLELAYCLQKCNVPLFVQHDAAQLYLKLWNLIKDQITDVHLVE 162
+ + ++Q S K V +L + F+QHD +L L + +++++ +
Sbjct: 260 LQRVFYELQHS-DKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEG 318
Query: 163 RLQALYTIRVKDSLICVDCAMESSRNSSMLTLPLSLFDVDSKPLKTLEDALHCFFQPREL 222
+ L+ ++ + C + S R + LS+ K K + ++ + +L
Sbjct: 319 TIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSI-----KGKKNIFESFVDYVAVEQL 373
Query: 223 SSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSI--RNSQTRKICHSLYFPQSLD 280
+K G + K V LT LP L + LMRF + Q KI FP+ L
Sbjct: 374 DGDNKYDAGEHGLQEAEKGVKFLT-LPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLP 432
Query: 281 FSQILPMKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIRNAVDGKWFCFNDSNIC 340
+ L + + Y L AV+ H G GHY VY+ DGKW F+D +
Sbjct: 433 LDEFLQK------TDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVS 486
Query: 341 LVSWED-IQCTYG----NPNYHWQETAYLLVYMK 369
+ E+ I+ YG + + AY+LVY++
Sbjct: 487 RCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIR 520
>gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 90.9 bits (224), Expect = 2e-18
Identities = 78/354 (22%), Positives = 143/354 (40%), Gaps = 57/354 (16%)
Query: 54 LVGLHNIGQTCCLNSLIQVFVMNVDFTRILKRITVPRGADEQ-----RRSVPFQMLLLLE 108
L GL N+G TC +NS++Q R + + V + ++++
Sbjct: 776 LTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMK 835
Query: 109 KMQDSRQKAVRPLELAYCLQKCNVPL--FVQHDAAQLYLKLWNLI--------------- 151
+ + + + P + + K N + Q D+ +L L L + +
Sbjct: 836 ALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKE 895
Query: 152 --KDQITDVHLVER------------LQALYTIRVKDSLICVDCAMESSRNSSMLTLPLS 197
D + D E + AL+ + K ++ C+ C +S + + L L
Sbjct: 896 ENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLP 955
Query: 198 LFDVDSKPLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLM 257
L TL+D L F + +L+ ++ +C +C + + +++ LP L +HL
Sbjct: 956 LASTSKC---TLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLK 1012
Query: 258 RFSIRNSQTRKICHSLYFP-QSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHVGMADS 316
RFS +K+ S+ FP ++LD SQ + + + +Y LF+V H G D
Sbjct: 1013 RFSYDGRWKQKLQTSVDFPLENLDLSQYVIGPKNNLK-------KYNLFSVSNHYGGLDG 1065
Query: 317 GHYCVYIRNAVDGKWFCFNDSNICLVSWEDIQCTYGNPNYHWQETAYLLVYMKM 370
GHY Y +NA +WF F+D + +S ++ AY+L Y +
Sbjct: 1066 GHYTAYCKNAARQRWFKFDDHEVSDISVSSVK----------SSAAYILFYTSL 1109
>gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 90.9 bits (224), Expect = 2e-18
Identities = 78/354 (22%), Positives = 143/354 (40%), Gaps = 57/354 (16%)
Query: 54 LVGLHNIGQTCCLNSLIQVFVMNVDFTRILKRITVPRGADEQ-----RRSVPFQMLLLLE 108
L GL N+G TC +NS++Q R + + V + ++++
Sbjct: 776 LTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMK 835
Query: 109 KMQDSRQKAVRPLELAYCLQKCNVPL--FVQHDAAQLYLKLWNLI--------------- 151
+ + + + P + + K N + Q D+ +L L L + +
Sbjct: 836 ALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKE 895
Query: 152 --KDQITDVHLVER------------LQALYTIRVKDSLICVDCAMESSRNSSMLTLPLS 197
D + D E + AL+ + K ++ C+ C +S + + L L
Sbjct: 896 ENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLP 955
Query: 198 LFDVDSKPLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLM 257
L TL+D L F + +L+ ++ +C +C + + +++ LP L +HL
Sbjct: 956 LASTSKC---TLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLK 1012
Query: 258 RFSIRNSQTRKICHSLYFP-QSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHVGMADS 316
RFS +K+ S+ FP ++LD SQ + + + +Y LF+V H G D
Sbjct: 1013 RFSYDGRWKQKLQTSVDFPLENLDLSQYVIGPKNNLK-------KYNLFSVSNHYGGLDG 1065
Query: 317 GHYCVYIRNAVDGKWFCFNDSNICLVSWEDIQCTYGNPNYHWQETAYLLVYMKM 370
GHY Y +NA +WF F+D + +S ++ AY+L Y +
Sbjct: 1066 GHYTAYCKNAARQRWFKFDDHEVSDISVSSVK----------SSAAYILFYTSL 1109
>gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 90.9 bits (224), Expect = 2e-18
Identities = 78/354 (22%), Positives = 143/354 (40%), Gaps = 57/354 (16%)
Query: 54 LVGLHNIGQTCCLNSLIQVFVMNVDFTRILKRITVPRGADEQ-----RRSVPFQMLLLLE 108
L GL N+G TC +NS++Q R + + V + ++++
Sbjct: 776 LTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMK 835
Query: 109 KMQDSRQKAVRPLELAYCLQKCNVPL--FVQHDAAQLYLKLWNLI--------------- 151
+ + + + P + + K N + Q D+ +L L L + +
Sbjct: 836 ALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKE 895
Query: 152 --KDQITDVHLVER------------LQALYTIRVKDSLICVDCAMESSRNSSMLTLPLS 197
D + D E + AL+ + K ++ C+ C +S + + L L
Sbjct: 896 ENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLP 955
Query: 198 LFDVDSKPLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLM 257
L TL+D L F + +L+ ++ +C +C + + +++ LP L +HL
Sbjct: 956 LASTSKC---TLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLK 1012
Query: 258 RFSIRNSQTRKICHSLYFP-QSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHVGMADS 316
RFS +K+ S+ FP ++LD SQ + + + +Y LF+V H G D
Sbjct: 1013 RFSYDGRWKQKLQTSVDFPLENLDLSQYVIGPKNNLK-------KYNLFSVSNHYGGLDG 1065
Query: 317 GHYCVYIRNAVDGKWFCFNDSNICLVSWEDIQCTYGNPNYHWQETAYLLVYMKM 370
GHY Y +NA +WF F+D + +S ++ AY+L Y +
Sbjct: 1066 GHYTAYCKNAARQRWFKFDDHEVSDISVSSVK----------SSAAYILFYTSL 1109
>gi|110347427 ubiquitin specific protease 34 [Homo sapiens]
Length = 3546
Score = 90.1 bits (222), Expect = 3e-18
Identities = 85/383 (22%), Positives = 154/383 (40%), Gaps = 56/383 (14%)
Query: 36 MKREQPRERPRAWDY-PHG-------LVGLHNIGQTCCLNSLIQVFVMNVDFTRILKRIT 87
M + P WDY PH VGL N+G TC L S IQ M + + + T
Sbjct: 1867 MAQHMQSHAPYKWDYWPHEDVRAECRFVGLTNLGATCYLASTIQQLYMIPEARQAV--FT 1924
Query: 88 VPRGADEQRRSVPFQMLLLLEKMQDSRQKAV--RPLELAYCLQKCNVPLFVQHDAAQLYL 145
D + ++ ++ + + +S KA RP Y + K + Q D + +
Sbjct: 1925 AKYSEDMKHKTTLLELQKMFTYLMESECKAYNPRPFCKTYTMDKQPLNTGEQKDMTEFFT 1984
Query: 146 KLWNLIKDQITDVHLVERLQALYTIRVKDSLICVDCAMESSRNSSMLTLPLSLFDVDSKP 205
L I++ + L +++L+ + ++++ +DC S T+ + D
Sbjct: 1985 DLITKIEEMSPE--LKNTVKSLFGGVITNNVVSLDCEHVSQTAEEFYTVRCQVAD----- 2037
Query: 206 LKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMR--FSIRN 263
+K + ++L L + C +CGKK R ++ LP+ L+ + MR F++
Sbjct: 2038 MKNIYESLDEVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMVT 2097
Query: 264 SQTRKICHSLYFPQSLDFSQILP------------MKRESCDAEEQSGGQYELFAVIAHV 311
K+ FP LD + K S +++ +Y+L V H
Sbjct: 2098 MMKEKVNTHFSFPLRLDMTPYTEDFLMGKSERKEGFKEVSDHSKDSESYEYDLIGVTVHT 2157
Query: 312 GMADSGHYCVYIRNAV------DGKWFCFNDSNI-----------------CLVSWEDIQ 348
G AD GHY +IR+ V + KW+ FND+ + +++ +
Sbjct: 2158 GTADGGHYYSFIRDIVNPHAYKNNKWYLFNDAEVKPFDSAQLASECFGGEMTTKTYDSVT 2217
Query: 349 CTYGNPNYHWQETAYLLVYMKME 371
+ + ++ +AY+L Y +ME
Sbjct: 2218 DKFMDFSFEKTHSAYMLFYKRME 2240
>gi|183396780 ubiquitin specific protease 20 [Homo sapiens]
Length = 914
Score = 86.7 bits (213), Expect = 3e-17
Identities = 55/165 (33%), Positives = 79/165 (47%), Gaps = 15/165 (9%)
Query: 205 PLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNS 264
P+ TLED L FF EL + CE C K G + K+ LP+ L IHL RF
Sbjct: 535 PVVTLEDCLAAFFAADELKGDNMYSCERCKKLRNGVKYCKVLRLPEILCIHLKRFRHEVM 594
Query: 265 QTRKICHSLYFPQSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIR 324
+ KI + FP L+ + P + C ++ + Y+L +VI H G A SGHY Y +
Sbjct: 595 YSFKINSHVSFP--LEGLDLRPFLAKECTSQITT---YDLLSVICHHGTAGSGHYIAYCQ 649
Query: 325 NAVDGKWFCFNDSNICLVSWEDIQCTYGNPNYHWQETAYLLVYMK 369
N ++G+W+ F+D + V +Q G Y+L Y K
Sbjct: 650 NVINGQWYEFDDQYVTEVHETVVQNAEG----------YVLFYRK 684
Score = 32.0 bits (71), Expect = 0.92
Identities = 29/137 (21%), Positives = 54/137 (39%), Gaps = 17/137 (12%)
Query: 24 ADLEEKKEEDSNMKREQPRERPRAWDYPHGLVGLHNIGQTCCLNSLIQVFVMNVDFTRIL 83
AD E + ED ++K P GL G+ N+G +C +N+ +Q T+
Sbjct: 127 ADEGESESEDDDLK-------------PRGLTGMKNLGNSCYMNAALQALSNCPPLTQFF 173
Query: 84 KRITVPRGADEQRRSVPFQMLLLLEKMQDSRQKAVRPLELAYCLQKCNVPLF---VQHDA 140
D++ L+ E R V P L++ ++ N P+F Q D
Sbjct: 174 LECGGLVRTDKKPALCKSYQKLVSEVWHKKRPSYVVPTSLSHGIKLVN-PMFRGYAQQDT 232
Query: 141 AQLYLKLWNLIKDQITD 157
+ L + + +++ +
Sbjct: 233 QEFLRCLMDQLHEELKE 249
>gi|183397136 ubiquitin specific protease 20 [Homo sapiens]
Length = 914
Score = 86.7 bits (213), Expect = 3e-17
Identities = 55/165 (33%), Positives = 79/165 (47%), Gaps = 15/165 (9%)
Query: 205 PLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNS 264
P+ TLED L FF EL + CE C K G + K+ LP+ L IHL RF
Sbjct: 535 PVVTLEDCLAAFFAADELKGDNMYSCERCKKLRNGVKYCKVLRLPEILCIHLKRFRHEVM 594
Query: 265 QTRKICHSLYFPQSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIR 324
+ KI + FP L+ + P + C ++ + Y+L +VI H G A SGHY Y +
Sbjct: 595 YSFKINSHVSFP--LEGLDLRPFLAKECTSQITT---YDLLSVICHHGTAGSGHYIAYCQ 649
Query: 325 NAVDGKWFCFNDSNICLVSWEDIQCTYGNPNYHWQETAYLLVYMK 369
N ++G+W+ F+D + V +Q G Y+L Y K
Sbjct: 650 NVINGQWYEFDDQYVTEVHETVVQNAEG----------YVLFYRK 684
Score = 32.0 bits (71), Expect = 0.92
Identities = 29/137 (21%), Positives = 54/137 (39%), Gaps = 17/137 (12%)
Query: 24 ADLEEKKEEDSNMKREQPRERPRAWDYPHGLVGLHNIGQTCCLNSLIQVFVMNVDFTRIL 83
AD E + ED ++K P GL G+ N+G +C +N+ +Q T+
Sbjct: 127 ADEGESESEDDDLK-------------PRGLTGMKNLGNSCYMNAALQALSNCPPLTQFF 173
Query: 84 KRITVPRGADEQRRSVPFQMLLLLEKMQDSRQKAVRPLELAYCLQKCNVPLF---VQHDA 140
D++ L+ E R V P L++ ++ N P+F Q D
Sbjct: 174 LECGGLVRTDKKPALCKSYQKLVSEVWHKKRPSYVVPTSLSHGIKLVN-PMFRGYAQQDT 232
Query: 141 AQLYLKLWNLIKDQITD 157
+ L + + +++ +
Sbjct: 233 QEFLRCLMDQLHEELKE 249
>gi|183397134 ubiquitin specific protease 20 [Homo sapiens]
Length = 914
Score = 86.7 bits (213), Expect = 3e-17
Identities = 55/165 (33%), Positives = 79/165 (47%), Gaps = 15/165 (9%)
Query: 205 PLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNS 264
P+ TLED L FF EL + CE C K G + K+ LP+ L IHL RF
Sbjct: 535 PVVTLEDCLAAFFAADELKGDNMYSCERCKKLRNGVKYCKVLRLPEILCIHLKRFRHEVM 594
Query: 265 QTRKICHSLYFPQSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIR 324
+ KI + FP L+ + P + C ++ + Y+L +VI H G A SGHY Y +
Sbjct: 595 YSFKINSHVSFP--LEGLDLRPFLAKECTSQITT---YDLLSVICHHGTAGSGHYIAYCQ 649
Query: 325 NAVDGKWFCFNDSNICLVSWEDIQCTYGNPNYHWQETAYLLVYMK 369
N ++G+W+ F+D + V +Q G Y+L Y K
Sbjct: 650 NVINGQWYEFDDQYVTEVHETVVQNAEG----------YVLFYRK 684
Score = 32.0 bits (71), Expect = 0.92
Identities = 29/137 (21%), Positives = 54/137 (39%), Gaps = 17/137 (12%)
Query: 24 ADLEEKKEEDSNMKREQPRERPRAWDYPHGLVGLHNIGQTCCLNSLIQVFVMNVDFTRIL 83
AD E + ED ++K P GL G+ N+G +C +N+ +Q T+
Sbjct: 127 ADEGESESEDDDLK-------------PRGLTGMKNLGNSCYMNAALQALSNCPPLTQFF 173
Query: 84 KRITVPRGADEQRRSVPFQMLLLLEKMQDSRQKAVRPLELAYCLQKCNVPLF---VQHDA 140
D++ L+ E R V P L++ ++ N P+F Q D
Sbjct: 174 LECGGLVRTDKKPALCKSYQKLVSEVWHKKRPSYVVPTSLSHGIKLVN-PMFRGYAQQDT 232
Query: 141 AQLYLKLWNLIKDQITD 157
+ L + + +++ +
Sbjct: 233 QEFLRCLMDQLHEELKE 249
>gi|41152235 ubiquitin specific protease 51 [Homo sapiens]
Length = 711
Score = 85.1 bits (209), Expect = 9e-17
Identities = 94/384 (24%), Positives = 152/384 (39%), Gaps = 57/384 (14%)
Query: 28 EKKEEDSNMKREQPRERPRAWDYPHGLVGLHNIGQTCCLNSLIQVFV---MNVDFTRILK 84
E KE++ + + + + R ++ Y GL GL N+G TC +N ++Q + DF K
Sbjct: 337 ETKEQEPKLVKPKKKRRKKSV-YTVGLRGLINLGNTCFMNCIVQALTHIPLLKDFFLSDK 395
Query: 85 RITVPRGADEQRRSVPFQMLLLLEKMQDSRQKAVRPLELAYCL--QKCNVPLFVQHDAAQ 142
+ + +M L M + P +L + + ++ + Q DA +
Sbjct: 396 HKCIMTSPS---LCLVCEMSSLFHAMYSGSRTPHIPYKLLHLIWIHAEHLAGYRQQDAHE 452
Query: 143 LYLKLWNLIKDQITDVHLVER----------LQALYTIRVKDSLICVDCAMESSRNSSM- 191
+ + +++ D + + ++T ++ + C C S+
Sbjct: 453 FLIAILDVLHRHSKDDSGGQEANNPNCCNCIIDQIFTGGLQSDVTCQACHSVSTTIDPCW 512
Query: 192 ---LTLPLSLFDVDSKP----------------LKTLEDALHCFFQPRELSSKSKCFCEN 232
L LP S DS+ + +L D L F +P L S +K C +
Sbjct: 513 DISLDLPGSCATFDSQNPERADSTVSRDDHIPGIPSLTDCLQWFTRPEHLGSSAKIKCNS 572
Query: 233 CGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTRKICHSLYFPQSLDFSQILPMKRESC 292
C + L + LP HL RF Q RKI + FP LD + L +ES
Sbjct: 573 CQSYQESTKQLTMKKLPIVACFHLKRFEHVGKQRRKINTFISFPLELDMTPFLASTKESR 632
Query: 293 DAEEQ-------SGGQYELFAVIAHVGMADSGHYCVYIRNAVDGKWFCFNDSNICLVSWE 345
E Q + +Y LFAVI H G +SGHY +IR D +WF +D+ I + E
Sbjct: 633 MKEGQPPTDCVPNENKYSLFAVINHHGTLESGHYTSFIRQQKD-QWFSCDDAIITKATIE 691
Query: 346 DIQCTYGNPNYHWQETAYLLVYMK 369
D+ + G YLL Y K
Sbjct: 692 DLLYSEG----------YLLFYHK 705
>gi|28565285 ubiquitin specific peptidase 2 isoform b [Homo sapiens]
Length = 396
Score = 84.7 bits (208), Expect = 1e-16
Identities = 91/356 (25%), Positives = 139/356 (39%), Gaps = 65/356 (18%)
Query: 53 GLVGLHNIGQTCCLNSLIQVFVMNVDFTRILKRITVPR--------GADEQRRSVPFQML 104
GL GL N+G TC +NS++Q + TR L+ + R G++ V
Sbjct: 56 GLAGLRNLGNTCFMNSILQC----LSNTRELRDYCLQRLYMRDLHHGSNAHTALVEEFAK 111
Query: 105 LLLEKMQDSRQKAVRPLELAYCLQKCNVPLFV---QHDAAQLYLKLWNLIKDQITDV--- 158
L+ S V P E +Q+ P FV Q DA + L + + +++ V
Sbjct: 112 LIQTIWTSSPNDVVSPSEFKTQIQRY-APRFVGYNQQDAQEFLRFLLDGLHNEVNRVTLR 170
Query: 159 ---------HLVE-----------------RLQALYTIRVKDSLICVDCAMESSRNSSML 192
HL + R+ L+ ++K SL C DC S+
Sbjct: 171 PKSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFW 230
Query: 193 TLPLSLFDVDSKPLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTL 252
L L + P TL D + F + L K C C + R + + P+ L
Sbjct: 231 DLSLPIAK-RGYPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKIL 289
Query: 253 TIHLMRFSIRNSQTRKICHSLYFP-QSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHV 311
+HL RFS +T K+ + FP + LD + +E + Y L+AV H
Sbjct: 290 VLHLKRFSESRIRTSKLTTFVNFPLRDLDLREFA--------SENTNHAVYNLYAVSNHS 341
Query: 312 GMADSGHYCVYIRNAVDGKWFCFNDSNICLVSWEDIQCTYGNPNYHWQETAYLLVY 367
G GHY Y R+ G+W FNDS++ +S ++ + AYLL Y
Sbjct: 342 GTTMGGHYTAYCRSPGTGEWHTFNDSSVTPMSSSQVRTS----------DAYLLFY 387
>gi|188528692 ubiquitin specific peptidase 2 isoform a [Homo
sapiens]
Length = 605
Score = 84.7 bits (208), Expect = 1e-16
Identities = 91/356 (25%), Positives = 139/356 (39%), Gaps = 65/356 (18%)
Query: 53 GLVGLHNIGQTCCLNSLIQVFVMNVDFTRILKRITVPR--------GADEQRRSVPFQML 104
GL GL N+G TC +NS++Q + TR L+ + R G++ V
Sbjct: 265 GLAGLRNLGNTCFMNSILQC----LSNTRELRDYCLQRLYMRDLHHGSNAHTALVEEFAK 320
Query: 105 LLLEKMQDSRQKAVRPLELAYCLQKCNVPLFV---QHDAAQLYLKLWNLIKDQITDV--- 158
L+ S V P E +Q+ P FV Q DA + L + + +++ V
Sbjct: 321 LIQTIWTSSPNDVVSPSEFKTQIQRY-APRFVGYNQQDAQEFLRFLLDGLHNEVNRVTLR 379
Query: 159 ---------HLVE-----------------RLQALYTIRVKDSLICVDCAMESSRNSSML 192
HL + R+ L+ ++K SL C DC S+
Sbjct: 380 PKSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFW 439
Query: 193 TLPLSLFDVDSKPLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTL 252
L L + P TL D + F + L K C C + R + + P+ L
Sbjct: 440 DLSLPIAK-RGYPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKIL 498
Query: 253 TIHLMRFSIRNSQTRKICHSLYFP-QSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHV 311
+HL RFS +T K+ + FP + LD + +E + Y L+AV H
Sbjct: 499 VLHLKRFSESRIRTSKLTTFVNFPLRDLDLREFA--------SENTNHAVYNLYAVSNHS 550
Query: 312 GMADSGHYCVYIRNAVDGKWFCFNDSNICLVSWEDIQCTYGNPNYHWQETAYLLVY 367
G GHY Y R+ G+W FNDS++ +S ++ + AYLL Y
Sbjct: 551 GTTMGGHYTAYCRSPGTGEWHTFNDSSVTPMSSSQVRTS----------DAYLLFY 596
>gi|42516561 ubiquitin specific protease 33 isoform 3 [Homo sapiens]
Length = 828
Score = 82.8 bits (203), Expect = 5e-16
Identities = 54/165 (32%), Positives = 78/165 (47%), Gaps = 15/165 (9%)
Query: 205 PLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNS 264
P+ TL+D L FF EL + CE C K G + K+ + P+ L IHL RF
Sbjct: 557 PVVTLQDCLAAFFARDELKGDNMYSCEKCKKLRNGVKFCKVQNFPEILCIHLKRFRHELM 616
Query: 265 QTRKICHSLYFPQSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIR 324
+ KI + FP L+ + P + A+ + Y+L +VI H G A SGHY Y R
Sbjct: 617 FSTKISTHVSFP--LEGLDLQPFLAKDSPAQIVT---YDLLSVICHHGTASSGHYIAYCR 671
Query: 325 NAVDGKWFCFNDSNICLVSWEDIQCTYGNPNYHWQETAYLLVYMK 369
N ++ W+ F+D ++ VS +Q AY+L Y K
Sbjct: 672 NNLNNLWYEFDDQSVTEVSESTVQ----------NAEAYVLFYRK 706
Score = 34.3 bits (77), Expect = 0.19
Identities = 41/187 (21%), Positives = 77/187 (41%), Gaps = 24/187 (12%)
Query: 53 GLVGLHNIGQTCCLNSLIQVFVMNVDFTRILKRITVPRGADEQRRSVPFQMLLLLEKMQD 112
GL GL NIG TC +N+ +Q T+ D++ + L+ E
Sbjct: 183 GLTGLKNIGNTCYMNAALQALSNCPPLTQFFLDCGGLARTDKKPAICKSYLKLMTELWHK 242
Query: 113 SRQKAVRPLELAYCLQKCNVPL--FVQHDAAQLYLKLWNLIKDQITDVHLVERLQALYTI 170
SR +V P L ++ N + Q DA + L +L+ +++ + ++E + TI
Sbjct: 243 SRPGSVVPTTLFQGIKTVNPTFRGYSQQDAQEFLRCLMDLLHEELKE-QVMEVEEDPQTI 301
Query: 171 RVKDSLICVDCAMESSRNSSMLTLPLSLFDVDSKPLKTLEDALHCFFQPRELSSKSKCFC 230
+++ ME ++ S DVD + ++ ++ E + S+CF
Sbjct: 302 TTEET-------MEEDKSQS---------DVDFQSCESCSNS-----DRAENENGSRCFS 340
Query: 231 ENCGKKT 237
E+ + T
Sbjct: 341 EDNNETT 347
>gi|42516567 ubiquitin specific protease 33 isoform 1 [Homo sapiens]
Length = 942
Score = 82.8 bits (203), Expect = 5e-16
Identities = 54/165 (32%), Positives = 78/165 (47%), Gaps = 15/165 (9%)
Query: 205 PLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNS 264
P+ TL+D L FF EL + CE C K G + K+ + P+ L IHL RF
Sbjct: 565 PVVTLQDCLAAFFARDELKGDNMYSCEKCKKLRNGVKFCKVQNFPEILCIHLKRFRHELM 624
Query: 265 QTRKICHSLYFPQSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIR 324
+ KI + FP L+ + P + A+ + Y+L +VI H G A SGHY Y R
Sbjct: 625 FSTKISTHVSFP--LEGLDLQPFLAKDSPAQIVT---YDLLSVICHHGTASSGHYIAYCR 679
Query: 325 NAVDGKWFCFNDSNICLVSWEDIQCTYGNPNYHWQETAYLLVYMK 369
N ++ W+ F+D ++ VS +Q AY+L Y K
Sbjct: 680 NNLNNLWYEFDDQSVTEVSESTVQ----------NAEAYVLFYRK 714
Score = 34.3 bits (77), Expect = 0.19
Identities = 41/187 (21%), Positives = 77/187 (41%), Gaps = 24/187 (12%)
Query: 53 GLVGLHNIGQTCCLNSLIQVFVMNVDFTRILKRITVPRGADEQRRSVPFQMLLLLEKMQD 112
GL GL NIG TC +N+ +Q T+ D++ + L+ E
Sbjct: 183 GLTGLKNIGNTCYMNAALQALSNCPPLTQFFLDCGGLARTDKKPAICKSYLKLMTELWHK 242
Query: 113 SRQKAVRPLELAYCLQKCNVPL--FVQHDAAQLYLKLWNLIKDQITDVHLVERLQALYTI 170
SR +V P L ++ N + Q DA + L +L+ +++ + ++E + TI
Sbjct: 243 SRPGSVVPTTLFQGIKTVNPTFRGYSQQDAQEFLRCLMDLLHEELKE-QVMEVEEDPQTI 301
Query: 171 RVKDSLICVDCAMESSRNSSMLTLPLSLFDVDSKPLKTLEDALHCFFQPRELSSKSKCFC 230
+++ ME ++ S DVD + ++ ++ E + S+CF
Sbjct: 302 TTEET-------MEEDKSQS---------DVDFQSCESCSNS-----DRAENENGSRCFS 340
Query: 231 ENCGKKT 237
E+ + T
Sbjct: 341 EDNNETT 347
>gi|42516565 ubiquitin specific protease 33 isoform 2 [Homo sapiens]
Length = 911
Score = 82.8 bits (203), Expect = 5e-16
Identities = 54/165 (32%), Positives = 78/165 (47%), Gaps = 15/165 (9%)
Query: 205 PLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNS 264
P+ TL+D L FF EL + CE C K G + K+ + P+ L IHL RF
Sbjct: 534 PVVTLQDCLAAFFARDELKGDNMYSCEKCKKLRNGVKFCKVQNFPEILCIHLKRFRHELM 593
Query: 265 QTRKICHSLYFPQSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIR 324
+ KI + FP L+ + P + A+ + Y+L +VI H G A SGHY Y R
Sbjct: 594 FSTKISTHVSFP--LEGLDLQPFLAKDSPAQIVT---YDLLSVICHHGTASSGHYIAYCR 648
Query: 325 NAVDGKWFCFNDSNICLVSWEDIQCTYGNPNYHWQETAYLLVYMK 369
N ++ W+ F+D ++ VS +Q AY+L Y K
Sbjct: 649 NNLNNLWYEFDDQSVTEVSESTVQ----------NAEAYVLFYRK 683
Score = 34.3 bits (77), Expect = 0.19
Identities = 41/187 (21%), Positives = 77/187 (41%), Gaps = 24/187 (12%)
Query: 53 GLVGLHNIGQTCCLNSLIQVFVMNVDFTRILKRITVPRGADEQRRSVPFQMLLLLEKMQD 112
GL GL NIG TC +N+ +Q T+ D++ + L+ E
Sbjct: 152 GLTGLKNIGNTCYMNAALQALSNCPPLTQFFLDCGGLARTDKKPAICKSYLKLMTELWHK 211
Query: 113 SRQKAVRPLELAYCLQKCNVPL--FVQHDAAQLYLKLWNLIKDQITDVHLVERLQALYTI 170
SR +V P L ++ N + Q DA + L +L+ +++ + ++E + TI
Sbjct: 212 SRPGSVVPTTLFQGIKTVNPTFRGYSQQDAQEFLRCLMDLLHEELKE-QVMEVEEDPQTI 270
Query: 171 RVKDSLICVDCAMESSRNSSMLTLPLSLFDVDSKPLKTLEDALHCFFQPRELSSKSKCFC 230
+++ ME ++ S DVD + ++ ++ E + S+CF
Sbjct: 271 TTEET-------MEEDKSQS---------DVDFQSCESCSNS-----DRAENENGSRCFS 309
Query: 231 ENCGKKT 237
E+ + T
Sbjct: 310 EDNNETT 316
>gi|223005906 X-linked ubiquitin thioesterase 27 [Homo sapiens]
Length = 438
Score = 79.3 bits (194), Expect = 5e-15
Identities = 92/388 (23%), Positives = 150/388 (38%), Gaps = 64/388 (16%)
Query: 28 EKKEEDSNMKREQPRERPRAWDYPHGLVGLHNIGQTCCLNSLIQVFVMNVDFTRILKRIT 87
E + + + PR R + GL GL N+G TC +N ++Q T IL+
Sbjct: 51 ETTKPELELLGHNPRRRRITSSFTIGLRGLINLGNTCFMNCIVQALT----HTPILRDFF 106
Query: 88 VPRGADEQRRSVPFQMLLLLEKMQDSRQKAVR-------PLELAYC--LQKCNVPLFVQH 138
+ +D R +P L L+ +M ++ P +L + + ++ + Q
Sbjct: 107 L---SDRHRCEMPSPELCLVCEMSSLFRELYSGNPSPHVPYKLLHLVWIHARHLAGYRQQ 163
Query: 139 DAAQLYLKLWNLI----------KDQITDVHLVERLQALYTIRVKDSLICVDCAMESSRN 188
DA + + +++ K H + ++T ++ + C C S+
Sbjct: 164 DAHEFLIAALDVLHRHCKGDDVGKAANNPNHCNCIIDQIFTGGLQSDVTCQACHGVSTTI 223
Query: 189 SSMLTLPLSL---------------FDVDSKP----LKTLEDALHCFFQPRELSSKSKCF 229
+ L L V+ + + TL D L F +P L S +K
Sbjct: 224 DPCWDISLDLPGSCTSFWPMSPGRESSVNGESHIPGITTLTDCLRRFTRPEHLGSSAKIK 283
Query: 230 CENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTRKICHSLYFPQSLDFSQILPMKR 289
C +C + L + LP H RF Q RKI + FP LD + + +
Sbjct: 284 CGSCQSYQESTKQLTMNKLPVVACFHFKRFEHSAKQRRKITTYISFPLELDMTPFMASSK 343
Query: 290 ES-----CDAEEQSG---GQYELFAVIAHVGMADSGHYCVYIRNAVDGKWFCFNDSNICL 341
ES SG +Y LFAV+ H G +SGHY +IR+ D +WF +D+ I
Sbjct: 344 ESRMNGQLQLPTNSGNNENKYSLFAVVNHQGTLESGHYTSFIRHHKD-QWFKCDDAVITK 402
Query: 342 VSWEDIQCTYGNPNYHWQETAYLLVYMK 369
S +D+ + G YLL Y K
Sbjct: 403 ASIKDVLDSEG----------YLLFYHK 420
>gi|41055953 ubiquitin thioesterase 40 [Homo sapiens]
Length = 1247
Score = 79.3 bits (194), Expect = 5e-15
Identities = 77/310 (24%), Positives = 129/310 (41%), Gaps = 28/310 (9%)
Query: 54 LVGLHNIGQTCCLNSLIQVFVMNVDFTRILKRITVPR--------GADEQRRSVPFQMLL 105
L G+ N G TC LNSL+Q +F L + D + R +P Q+
Sbjct: 52 LSGIRNQGGTCYLNSLLQTLHFTPEFREALFSLGPEELGLFEDKDKPDAKVRIIPLQLQR 111
Query: 106 LLEKMQDSRQKAVRPLELAYCLQKCNVPLFVQHDAAQLYLKLWNLIKDQITDVHLVERLQ 165
L ++ Q+A +L + QHD +L L++ ++ + + +
Sbjct: 112 LFAQLLLLDQEAASTADLTDSFGWTSNEEMRQHDVQELNRILFSALETSLVGTSGHDLIY 171
Query: 166 ALYTIRVKDSLICVDCAMESSRNSSMLTLPLSLFDVDSKPLKTLEDALHCFFQPRELSSK 225
LY + + ++C +C S R L L +++ +V LEDAL + E+
Sbjct: 172 RLYHGTIVNQIVCKECKNVSERQEDFLDLTVAVKNVSG-----LEDALWNMYVEEEVFDC 226
Query: 226 SKCF-CENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIR--NSQTRKICHSLYFPQSLDFS 282
+ C C + + + KL LP LT+ L+RF+ + K FP ++
Sbjct: 227 DNLYHCGTCDRLVKAAKSAKLRKLPPFLTVSLLRFNFDFVKCERYKETSCYTFPLRINLK 286
Query: 283 QILPMKRESCDAEEQSGGQY--ELFAVIAHVGMADSGHYCVYIRNAVD--GKWFCFNDSN 338
C+ E +Y +LF+VI H G GHY VYI++ VD G W + +
Sbjct: 287 PF-------CEQSELDDLEYIYDLFSVIIHKGGCYGGHYHVYIKD-VDHLGNWQFQEEKS 338
Query: 339 ICLVSWEDIQ 348
V+ +D+Q
Sbjct: 339 KPDVNLKDLQ 348
>gi|45267835 ubiquitin specific protease 50 [Homo sapiens]
Length = 339
Score = 78.2 bits (191), Expect = 1e-14
Identities = 71/314 (22%), Positives = 127/314 (40%), Gaps = 52/314 (16%)
Query: 51 PH--GLVGLHNIGQTCCLNSLIQV---------FVMNVDFTRILKRITVPRGADEQRRSV 99
PH G+ GL N+G TCC+N++ Q + + + L++ +P E +
Sbjct: 38 PHFQGVTGLWNLGNTCCVNAISQCLCSILPLVEYFLTGKYITALQKFLLPSDCSEVATAF 97
Query: 100 PFQMLLLLEKMQDSRQKAVRPLELAYCLQKCNVPLF---VQHDAAQLYLKLWNLIKDQIT 156
+ L+ M V P E+ + P F +Q DA + + + N + + +
Sbjct: 98 AY----LMTDMWLGDSDCVSP-EIFWSALGNLYPAFTKKMQQDAQEFLICVLNELHEALK 152
Query: 157 DVHLVER----------------------LQALYTIRVKDSLICVDCAMESSRNSSMLTL 194
H R + L+ ++ S++C+ C + +N
Sbjct: 153 KYHYSRRRSYEKGSTQRCCRKWITTETSIITQLFEEQLNYSIVCLKCEKCTYKNEVFTVF 212
Query: 195 PLSLFDVDSKPLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTI 254
L + SK +L D L CFFQ L+ ++ C C K ++ P+ +
Sbjct: 213 SLP---IPSKYECSLRDCLQCFFQQDALTWNNEIHCSFCETKQETAVRASISKAPKIIIF 269
Query: 255 HLMRFSIRNSQTRKICHSLYFP-QSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHVGM 313
HL RF I+ + RK+ +++P +LD + + C + +Y L AV+ H G
Sbjct: 270 HLKRFDIQGTTKRKLRTDIHYPLTNLDLTPYI------CSIFRKY-PKYNLCAVVNHFGD 322
Query: 314 ADSGHYCVYIRNAV 327
D GHY + +N+V
Sbjct: 323 LDGGHYTAFCKNSV 336
>gi|14149627 ubiquitin specific peptidase 15 [Homo sapiens]
Length = 952
Score = 77.4 bits (189), Expect = 2e-14
Identities = 50/170 (29%), Positives = 76/170 (44%), Gaps = 20/170 (11%)
Query: 204 KPLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRN 263
KP L+D + F +L ++ +C NC + + + L L LP L +HL RFS
Sbjct: 754 KPFVKLKDCIELFTTKEKLGAEDPWYCPNCKEHQQATKKLDLWSLPPVLVVHLKRFSYSR 813
Query: 264 SQTRKICHSLYFP-QSLDFSQILPMKRESCDAEEQSGG-QYELFAVIAHVGMADSGHYCV 321
K+ + FP LD S+ L +G +Y L AV H G GHY
Sbjct: 814 YMRDKLDTLVDFPINDLDMSEFL--------INPNAGPCRYNLIAVSNHYGGMGGGHYTA 865
Query: 322 YIRNAVDGKWFCFNDSNICLVSWEDIQCTYGNPNYHWQETAYLLVYMKME 371
+ +N DGKW+ F+DS++ S + I + AY+L Y + +
Sbjct: 866 FAKNKDDGKWYYFDDSSVSTASEDQIV----------SKAAYVLFYQRQD 905
Score = 29.3 bits (64), Expect = 6.0
Identities = 12/19 (63%), Positives = 14/19 (73%)
Query: 53 GLVGLHNIGQTCCLNSLIQ 71
GL GL N+G TC +NS IQ
Sbjct: 258 GLCGLSNLGNTCFMNSAIQ 276
>gi|120587027 ubiquitin specific peptidase 31 [Homo sapiens]
Length = 1352
Score = 77.4 bits (189), Expect = 2e-14
Identities = 53/178 (29%), Positives = 78/178 (43%), Gaps = 26/178 (14%)
Query: 208 TLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTR 267
TL + + L+ C +C + +G L L LP L IHL RF +
Sbjct: 597 TLSQCFQLYTKEERLAPDDAWRCPHCKQLQQGSITLSLWTLPDVLIIHLKRFRQEGDRRM 656
Query: 268 KICHSLYFPQS-LDF---------------SQILPMKRESCDAEEQSGGQYELFAVIAHV 311
K+ + + FP + LD S P +R + Y+L+AV H
Sbjct: 657 KLQNMVKFPLTGLDMTPHVVKRSQSSWSLPSHWSPWRRPYGLGRDPEDYIYDLYAVCNHH 716
Query: 312 GMADSGHYCVYIRNAVDGKWFCFNDSNICLVSWEDIQCTYGNPNYHWQETAYLLVYMK 369
G GHY Y +N+VDG W+CF+DS++ +S ED CT +TAY+L Y +
Sbjct: 717 GTMQGGHYTAYCKNSVDGLWYCFDDSDVQQLS-EDEVCT---------QTAYILFYQR 764
>gi|40795665 ubiquitin specific protease 4 isoform a [Homo sapiens]
Length = 963
Score = 74.7 bits (182), Expect = 1e-13
Identities = 49/169 (28%), Positives = 75/169 (44%), Gaps = 18/169 (10%)
Query: 204 KPLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRN 263
K L D + F L +C NC K + + L LP+ L +HL RFS
Sbjct: 773 KTTVALRDCIELFTTMETLGEHDPWYCPNCKKHQQATKKFDLWSLPKILVVHLKRFSYNR 832
Query: 264 SQTRKICHSLYFP-QSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVY 322
K+ + FP + L+ S+ + C+ + Y+L AV H G GHY Y
Sbjct: 833 YWRDKLDTVVEFPIRGLNMSEFV------CNLSARPY-VYDLIAVSNHYGAMGVGHYTAY 885
Query: 323 IRNAVDGKWFCFNDSNICLVSWEDIQCTYGNPNYHWQETAYLLVYMKME 371
+N ++GKW+ F+DSN+ L S + I + AY+L Y + +
Sbjct: 886 AKNKLNGKWYYFDDSNVSLASEDQIV----------TKAAYVLFYQRRD 924
>gi|40795667 ubiquitin specific protease 4 isoform b [Homo sapiens]
Length = 916
Score = 74.7 bits (182), Expect = 1e-13
Identities = 49/169 (28%), Positives = 75/169 (44%), Gaps = 18/169 (10%)
Query: 204 KPLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRN 263
K L D + F L +C NC K + + L LP+ L +HL RFS
Sbjct: 726 KTTVALRDCIELFTTMETLGEHDPWYCPNCKKHQQATKKFDLWSLPKILVVHLKRFSYNR 785
Query: 264 SQTRKICHSLYFP-QSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVY 322
K+ + FP + L+ S+ + C+ + Y+L AV H G GHY Y
Sbjct: 786 YWRDKLDTVVEFPIRGLNMSEFV------CNLSARPY-VYDLIAVSNHYGAMGVGHYTAY 838
Query: 323 IRNAVDGKWFCFNDSNICLVSWEDIQCTYGNPNYHWQETAYLLVYMKME 371
+N ++GKW+ F+DSN+ L S + I + AY+L Y + +
Sbjct: 839 AKNKLNGKWYYFDDSNVSLASEDQIV----------TKAAYVLFYQRRD 877
>gi|150010639 ubiquitin thiolesterase 22 [Homo sapiens]
Length = 525
Score = 74.3 bits (181), Expect = 2e-13
Identities = 54/170 (31%), Positives = 75/170 (44%), Gaps = 19/170 (11%)
Query: 208 TLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTR 267
TL D L F +P L S +K C C + L + LP HL RF R
Sbjct: 361 TLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKKLPIVACFHLKRFEHSAKLRR 420
Query: 268 KICHSLYFPQSLDFSQILPMKRES-CDAEEQ-------SGGQYELFAVIAHVGMADSGHY 319
KI + FP LD + + +ES + + Q + +Y LFAV+ H G +SGHY
Sbjct: 421 KITTYVSFPLELDMTPFMASSKESRMNGQYQQPTDSLNNDNKYSLFAVVNHQGTLESGHY 480
Query: 320 CVYIRNAVDGKWFCFNDSNICLVSWEDIQCTYGNPNYHWQETAYLLVYMK 369
+IR D +WF +D+ I S +D+ + G YLL Y K
Sbjct: 481 TSFIRQHKD-QWFKCDDAIITKASIKDVLDSEG----------YLLFYHK 519
Score = 29.6 bits (65), Expect = 4.6
Identities = 13/44 (29%), Positives = 23/44 (52%)
Query: 28 EKKEEDSNMKREQPRERPRAWDYPHGLVGLHNIGQTCCLNSLIQ 71
E + + + + P+ R + GL GL N+G TC +N ++Q
Sbjct: 149 EPTKRELELLKHNPKRRKITSNCTIGLRGLINLGNTCFMNCIVQ 192
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.136 0.422
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,172,323
Number of Sequences: 37866
Number of extensions: 623241
Number of successful extensions: 3412
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 78
Number of HSP's successfully gapped in prelim test: 37
Number of HSP's that attempted gapping in prelim test: 3124
Number of HSP's gapped (non-prelim): 229
length of query: 372
length of database: 18,247,518
effective HSP length: 104
effective length of query: 268
effective length of database: 14,309,454
effective search space: 3834933672
effective search space used: 3834933672
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.