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Search of human proteins with 31542509
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|31542509 ADP-dependent glucokinase [Homo sapiens]
(496 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|31542509 ADP-dependent glucokinase [Homo sapiens] 997 0.0
gi|53832014 choroideremia-like Rab escort protein 2 [Homo sapiens] 31 3.0
gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 30 3.9
gi|239741359 PREDICTED: hypothetical protein XP_002342184 [Homo ... 30 3.9
gi|38045915 pregnancy-associated plasma protein A preproprotein ... 30 5.1
gi|166851804 tudor domain containing 9 [Homo sapiens] 30 5.1
gi|224465194 secernin 1 isoform a [Homo sapiens] 30 5.1
gi|224465192 secernin 1 isoform c [Homo sapiens] 30 5.1
gi|224465190 secernin 1 isoform b [Homo sapiens] 30 5.1
gi|224465187 secernin 1 isoform a [Homo sapiens] 30 5.1
gi|149192871 OTU domain containing 3 [Homo sapiens] 30 5.1
gi|19718780 semaphorin 6B precursor [Homo sapiens] 30 5.1
gi|6912492 mitogen-activated protein kinase 8 interacting protei... 30 5.1
gi|7706537 mitogen-activated protein kinase 8 interacting protei... 30 5.1
gi|188536103 cryptochrome 2 (photolyase-like) isoform 2 [Homo sa... 29 8.6
gi|188536100 cryptochrome 2 (photolyase-like) isoform 1 [Homo sa... 29 8.6
gi|41152110 adrenomedullin 2 precursor [Homo sapiens] 29 8.6
gi|93204879 PR domain containing 15 isoform 1 [Homo sapiens] 29 8.6
gi|112821681 G protein-regulated inducer of neurite outgrowth 1 ... 29 8.6
gi|148539855 epidermal growth factor receptor pathway substrate ... 29 8.6
gi|148539853 epidermal growth factor receptor pathway substrate ... 29 8.6
>gi|31542509 ADP-dependent glucokinase [Homo sapiens]
Length = 496
Score = 997 bits (2577), Expect = 0.0
Identities = 496/496 (100%), Positives = 496/496 (100%)
Query: 1 MALWRGSAYAGFLALAVGCVFLLEPELPGSALRSLWSSLCLGPAPAPPGPVSPEGRLAAA 60
MALWRGSAYAGFLALAVGCVFLLEPELPGSALRSLWSSLCLGPAPAPPGPVSPEGRLAAA
Sbjct: 1 MALWRGSAYAGFLALAVGCVFLLEPELPGSALRSLWSSLCLGPAPAPPGPVSPEGRLAAA 60
Query: 61 WDALIVRPVRRWRRVAVGVNACVDVVLSGVKLLQALGLSPGNGKDHSILHSRNDLEEAFI 120
WDALIVRPVRRWRRVAVGVNACVDVVLSGVKLLQALGLSPGNGKDHSILHSRNDLEEAFI
Sbjct: 61 WDALIVRPVRRWRRVAVGVNACVDVVLSGVKLLQALGLSPGNGKDHSILHSRNDLEEAFI 120
Query: 121 HFMGKGAAAERFFSDKETFHDIAQVASEFPGAQHYVGGNAALIGQKFAANSDLKVLLCGP 180
HFMGKGAAAERFFSDKETFHDIAQVASEFPGAQHYVGGNAALIGQKFAANSDLKVLLCGP
Sbjct: 121 HFMGKGAAAERFFSDKETFHDIAQVASEFPGAQHYVGGNAALIGQKFAANSDLKVLLCGP 180
Query: 181 VGPKLHELLDDNVFVPPESLQEVDEFHLILEYQAGEEWGQLKAPHANRFIFSHDLSNGAM 240
VGPKLHELLDDNVFVPPESLQEVDEFHLILEYQAGEEWGQLKAPHANRFIFSHDLSNGAM
Sbjct: 181 VGPKLHELLDDNVFVPPESLQEVDEFHLILEYQAGEEWGQLKAPHANRFIFSHDLSNGAM 240
Query: 241 NMLEVFVSSLEEFQPDLVVLSGLHMMEGQSKELQRKRLLEVVTSISDIPTGIPVHLELAS 300
NMLEVFVSSLEEFQPDLVVLSGLHMMEGQSKELQRKRLLEVVTSISDIPTGIPVHLELAS
Sbjct: 241 NMLEVFVSSLEEFQPDLVVLSGLHMMEGQSKELQRKRLLEVVTSISDIPTGIPVHLELAS 300
Query: 301 MTNRELMSSIVHQVFPAVTSLGLNEQELLFLTQSASGPHSSLSSWNGVPDVGMVSDILFW 360
MTNRELMSSIVHQVFPAVTSLGLNEQELLFLTQSASGPHSSLSSWNGVPDVGMVSDILFW
Sbjct: 301 MTNRELMSSIVHQVFPAVTSLGLNEQELLFLTQSASGPHSSLSSWNGVPDVGMVSDILFW 360
Query: 361 ILKEHGRSKSRASDLTRIHFHTLVYHILATVDGHWANQLAAVAAGARVAGTQACATETID 420
ILKEHGRSKSRASDLTRIHFHTLVYHILATVDGHWANQLAAVAAGARVAGTQACATETID
Sbjct: 361 ILKEHGRSKSRASDLTRIHFHTLVYHILATVDGHWANQLAAVAAGARVAGTQACATETID 420
Query: 421 TSRVSLRAPQEFMTSHSEAGSRIVLNPNKPVVEWHREGISFHFTPVLVCKDPIRTVGLGD 480
TSRVSLRAPQEFMTSHSEAGSRIVLNPNKPVVEWHREGISFHFTPVLVCKDPIRTVGLGD
Sbjct: 421 TSRVSLRAPQEFMTSHSEAGSRIVLNPNKPVVEWHREGISFHFTPVLVCKDPIRTVGLGD 480
Query: 481 AISAEGLFYSEVHPHY 496
AISAEGLFYSEVHPHY
Sbjct: 481 AISAEGLFYSEVHPHY 496
>gi|53832014 choroideremia-like Rab escort protein 2 [Homo sapiens]
Length = 656
Score = 30.8 bits (68), Expect = 3.0
Identities = 24/66 (36%), Positives = 35/66 (53%), Gaps = 12/66 (18%)
Query: 294 VHLELASM-TNRELMSSIVHQVFPAVTSLGLNEQE---------LLFLTQSASGPHSSLS 343
VHL +S T RE + S+V ++F T +NE+E L F + +SG S S
Sbjct: 508 VHLTCSSSKTAREDLESVVKKLFTPYTETEINEEELTKPRLLWALYFNMRDSSG--ISRS 565
Query: 344 SWNGVP 349
S+NG+P
Sbjct: 566 SYNGLP 571
>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
theta, 150/170kDa [Homo sapiens]
Length = 1382
Score = 30.4 bits (67), Expect = 3.9
Identities = 12/39 (30%), Positives = 21/39 (53%)
Query: 238 GAMNMLEVFVSSLEEFQPDLVVLSGLHMMEGQSKELQRK 276
GA ++ + LEE PD ++ + +E + KELQ +
Sbjct: 649 GAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQER 687
>gi|239741359 PREDICTED: hypothetical protein XP_002342184 [Homo
sapiens]
Length = 168
Score = 30.4 bits (67), Expect = 3.9
Identities = 20/63 (31%), Positives = 27/63 (42%), Gaps = 6/63 (9%)
Query: 39 LCLGPAPAPP------GPVSPEGRLAAAWDALIVRPVRRWRRVAVGVNACVDVVLSGVKL 92
LC+ P APP GP G A A + RP+R WR + + + KL
Sbjct: 44 LCISPPEAPPPPLPAAGPAGVRGPQPPAGKAGLERPLRVWREGRLSGKGWRETPATTPKL 103
Query: 93 LQA 95
L+A
Sbjct: 104 LRA 106
>gi|38045915 pregnancy-associated plasma protein A preproprotein
[Homo sapiens]
Length = 1627
Score = 30.0 bits (66), Expect = 5.1
Identities = 26/90 (28%), Positives = 36/90 (40%), Gaps = 17/90 (18%)
Query: 1 MALWRGSAYAGFLALAVGCVFLLEPE------------LPGSALRSLWSSLCLGPAPAPP 48
M LW + G L+ A+GC P P + + + G +PP
Sbjct: 1 MRLWSWVLHLGLLSAALGCGLAERPRRARRDPRAGRPPRPAAGPATCATRAARGRRASPP 60
Query: 49 GPVSPEGRLAAAWDALIVRPVRRWRRVAVG 78
P P G AW+A+ V P RR +R A G
Sbjct: 61 PPPPPGG----AWEAVRV-PRRRQQREARG 85
>gi|166851804 tudor domain containing 9 [Homo sapiens]
Length = 1382
Score = 30.0 bits (66), Expect = 5.1
Identities = 35/125 (28%), Positives = 54/125 (43%), Gaps = 22/125 (17%)
Query: 241 NMLEVFVSSLEEFQPDLVVLSGLHMMEGQSKELQRKRLLEVVTSISDIPTGIPVHLELAS 300
++ EV VS ++ F + SG G L+R +L + + +I
Sbjct: 351 DIYEVAVSLIQMFDDLDMKESGNKAWSGAQFVLERSSVLVFLPGLGEINY---------- 400
Query: 301 MTNRELMSSIVH---QVFPAVTSLGLNEQELLFLTQSASGPHSSLSSWN------GVPDV 351
EL++S+VH QV+P +S+ L EQ +FL+ G + S N VPDV
Sbjct: 401 --MHELLTSLVHKRLQVYPLHSSVALEEQNNVFLS-PVPGYRKIILSTNIAESSVTVPDV 457
Query: 352 GMVSD 356
V D
Sbjct: 458 KYVID 462
>gi|224465194 secernin 1 isoform a [Homo sapiens]
Length = 414
Score = 30.0 bits (66), Expect = 5.1
Identities = 25/103 (24%), Positives = 40/103 (38%), Gaps = 13/103 (12%)
Query: 356 DILFWILKEHGRSKSRASDLTRIHFHTLVY--------HILATVDGHWANQLAAVAAGAR 407
D++ +L+EHG+ + D H Y +L T+ +WA + V G R
Sbjct: 128 DVIVSLLEEHGQGGNYFEDANSCHSFQSAYLIVDRDEAWVLETIGKYWAAE--KVTEGVR 185
Query: 408 VAGTQACATETIDTSRVSLRA---PQEFMTSHSEAGSRIVLNP 447
+Q T +D LR+ Q + T E V +P
Sbjct: 186 CICSQLSLTTKMDAEHPELRSYAQSQGWWTGEGEFNFSEVFSP 228
>gi|224465192 secernin 1 isoform c [Homo sapiens]
Length = 346
Score = 30.0 bits (66), Expect = 5.1
Identities = 25/103 (24%), Positives = 40/103 (38%), Gaps = 13/103 (12%)
Query: 356 DILFWILKEHGRSKSRASDLTRIHFHTLVY--------HILATVDGHWANQLAAVAAGAR 407
D++ +L+EHG+ + D H Y +L T+ +WA + V G R
Sbjct: 60 DVIVSLLEEHGQGGNYFEDANSCHSFQSAYLIVDRDEAWVLETIGKYWAAE--KVTEGVR 117
Query: 408 VAGTQACATETIDTSRVSLRA---PQEFMTSHSEAGSRIVLNP 447
+Q T +D LR+ Q + T E V +P
Sbjct: 118 CICSQLSLTTKMDAEHPELRSYAQSQGWWTGEGEFNFSEVFSP 160
>gi|224465190 secernin 1 isoform b [Homo sapiens]
Length = 434
Score = 30.0 bits (66), Expect = 5.1
Identities = 25/103 (24%), Positives = 40/103 (38%), Gaps = 13/103 (12%)
Query: 356 DILFWILKEHGRSKSRASDLTRIHFHTLVY--------HILATVDGHWANQLAAVAAGAR 407
D++ +L+EHG+ + D H Y +L T+ +WA + V G R
Sbjct: 148 DVIVSLLEEHGQGGNYFEDANSCHSFQSAYLIVDRDEAWVLETIGKYWAAE--KVTEGVR 205
Query: 408 VAGTQACATETIDTSRVSLRA---PQEFMTSHSEAGSRIVLNP 447
+Q T +D LR+ Q + T E V +P
Sbjct: 206 CICSQLSLTTKMDAEHPELRSYAQSQGWWTGEGEFNFSEVFSP 248
>gi|224465187 secernin 1 isoform a [Homo sapiens]
Length = 414
Score = 30.0 bits (66), Expect = 5.1
Identities = 25/103 (24%), Positives = 40/103 (38%), Gaps = 13/103 (12%)
Query: 356 DILFWILKEHGRSKSRASDLTRIHFHTLVY--------HILATVDGHWANQLAAVAAGAR 407
D++ +L+EHG+ + D H Y +L T+ +WA + V G R
Sbjct: 128 DVIVSLLEEHGQGGNYFEDANSCHSFQSAYLIVDRDEAWVLETIGKYWAAE--KVTEGVR 185
Query: 408 VAGTQACATETIDTSRVSLRA---PQEFMTSHSEAGSRIVLNP 447
+Q T +D LR+ Q + T E V +P
Sbjct: 186 CICSQLSLTTKMDAEHPELRSYAQSQGWWTGEGEFNFSEVFSP 228
>gi|149192871 OTU domain containing 3 [Homo sapiens]
Length = 398
Score = 30.0 bits (66), Expect = 5.1
Identities = 47/173 (27%), Positives = 69/173 (39%), Gaps = 32/173 (18%)
Query: 70 RRWRRVAVGVNACVDVVLSGVKLLQALGLS----PGNGK-------DHSILHSRNDL--- 115
RR R + G C + +S LQALGL PG+G D HSRN L
Sbjct: 37 RRNRPESGGGGGCEEEFVSFANQLQALGLKLREVPGDGNCLFRALGDQLEGHSRNHLKHR 96
Query: 116 EEAFIHFMGKGAAAERFFSDKETFH-DIAQVASEFPGAQHYVGGNAALIGQKFAANSDLK 174
+E + + + E F D F +A +A PG GN A++ FA N L
Sbjct: 97 QETVDYMIKQREDFEPFVEDDIPFEKHVASLAK--PGT---FAGNDAIVA--FARNHQLN 149
Query: 175 VLLCGPVGPKLHELLDDNVFVPPESLQEVDEFHLILEYQAGEEWGQLKAPHAN 227
V+ +H+L + V E H + Y+ GE + ++ + N
Sbjct: 150 VV--------IHQLNAPLWQIRGTEKSSVRELH--IAYRYGEHYDSVRRINDN 192
>gi|19718780 semaphorin 6B precursor [Homo sapiens]
Length = 888
Score = 30.0 bits (66), Expect = 5.1
Identities = 21/41 (51%), Positives = 23/41 (56%), Gaps = 8/41 (19%)
Query: 25 PELPGSALRSLWSSLCLGPAPAP-----PGPVSPEGRLAAA 60
P LP SA SL L L PA AP PG +P+GRL AA
Sbjct: 740 PLLPASASSSL---LLLAPARAPEQPPAPGEPTPDGRLYAA 777
>gi|6912492 mitogen-activated protein kinase 8 interacting protein 2
isoform 1 [Homo sapiens]
Length = 824
Score = 30.0 bits (66), Expect = 5.1
Identities = 14/20 (70%), Positives = 14/20 (70%), Gaps = 1/20 (5%)
Query: 40 CLGPAPAPPG-PVSPEGRLA 58
CL PAP PPG PVSP G A
Sbjct: 372 CLSPAPRPPGEPVSPAGGAA 391
>gi|7706537 mitogen-activated protein kinase 8 interacting protein 2
isoform 2 [Homo sapiens]
Length = 797
Score = 30.0 bits (66), Expect = 5.1
Identities = 14/20 (70%), Positives = 14/20 (70%), Gaps = 1/20 (5%)
Query: 40 CLGPAPAPPG-PVSPEGRLA 58
CL PAP PPG PVSP G A
Sbjct: 345 CLSPAPRPPGEPVSPAGGAA 364
>gi|188536103 cryptochrome 2 (photolyase-like) isoform 2 [Homo
sapiens]
Length = 532
Score = 29.3 bits (64), Expect = 8.6
Identities = 20/56 (35%), Positives = 24/56 (42%), Gaps = 2/56 (3%)
Query: 7 SAYAGFLALAV--GCVFLLEPELPGSALRSLWSSLCLGPAPAPPGPVSPEGRLAAA 60
S Y G LA CV L + + S GP P P GP SP+ +L AA
Sbjct: 450 SRYRGLCLLASVPSCVEDLSHPVAEPSSSQAGSMSSAGPRPLPSGPASPKRKLEAA 505
>gi|188536100 cryptochrome 2 (photolyase-like) isoform 1 [Homo
sapiens]
Length = 614
Score = 29.3 bits (64), Expect = 8.6
Identities = 20/56 (35%), Positives = 24/56 (42%), Gaps = 2/56 (3%)
Query: 7 SAYAGFLALAV--GCVFLLEPELPGSALRSLWSSLCLGPAPAPPGPVSPEGRLAAA 60
S Y G LA CV L + + S GP P P GP SP+ +L AA
Sbjct: 532 SRYRGLCLLASVPSCVEDLSHPVAEPSSSQAGSMSSAGPRPLPSGPASPKRKLEAA 587
>gi|41152110 adrenomedullin 2 precursor [Homo sapiens]
Length = 148
Score = 29.3 bits (64), Expect = 8.6
Identities = 18/41 (43%), Positives = 21/41 (51%), Gaps = 6/41 (14%)
Query: 16 AVGCVFLLEPELPGSALRSLWSSLCLGPAPAPPGPVSPEGR 56
A+GC+ LL +LPGS RS LG P P P P R
Sbjct: 8 ALGCISLLCLQLPGSLSRS------LGGDPRPVKPREPPAR 42
>gi|93204879 PR domain containing 15 isoform 1 [Homo sapiens]
Length = 1507
Score = 29.3 bits (64), Expect = 8.6
Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 11/76 (14%)
Query: 4 WRGSAYAGFLALAVGCVFLLEPELPGSALRSLWSSLCLGPAPAPPGPVSPEGRLA-AAWD 62
WR + G+++ + + L PGS+ P PA P P P G +A A D
Sbjct: 58 WRSESKPGWISRSRSGIALRAARPPGSS----------PPRPAAPRPPPPGGVVAEAPGD 107
Query: 63 ALIVRPVRRWRRVAVG 78
+I RP + RVA G
Sbjct: 108 VVIPRPRVQPMRVARG 123
>gi|112821681 G protein-regulated inducer of neurite outgrowth 1
[Homo sapiens]
Length = 1008
Score = 29.3 bits (64), Expect = 8.6
Identities = 18/52 (34%), Positives = 23/52 (44%), Gaps = 1/52 (1%)
Query: 38 SLCLGPAPAPPGPVSPEG-RLAAAWDALIVRPVRRWRRVAVGVNACVDVVLS 88
S C A PPGP + + A +W+A P R G ACV V +S
Sbjct: 776 SPCPEAAAPPPGPRTRDNFTKAPSWEASAPPPPREDAGTQAGAQACVSVAVS 827
>gi|148539855 epidermal growth factor receptor pathway substrate
8-like protein 1 isoform b [Homo sapiens]
Length = 596
Score = 29.3 bits (64), Expect = 8.6
Identities = 20/53 (37%), Positives = 28/53 (52%), Gaps = 5/53 (9%)
Query: 42 GPAPAPPGPVSPEGRLAAAWDALIVRPVRRWRRVAVGVNACVDV--VLSGVKL 92
GP+ A PGP +PE +L+ DA VR W + + VD VL+G +L
Sbjct: 488 GPSRAVPGPRAPEPQLSPGSDA---SEVRAWLQAKGFSSGTVDALGVLTGAQL 537
>gi|148539853 epidermal growth factor receptor pathway substrate
8-like protein 1 isoform a [Homo sapiens]
Length = 723
Score = 29.3 bits (64), Expect = 8.6
Identities = 20/53 (37%), Positives = 28/53 (52%), Gaps = 5/53 (9%)
Query: 42 GPAPAPPGPVSPEGRLAAAWDALIVRPVRRWRRVAVGVNACVDV--VLSGVKL 92
GP+ A PGP +PE +L+ DA VR W + + VD VL+G +L
Sbjct: 615 GPSRAVPGPRAPEPQLSPGSDA---SEVRAWLQAKGFSSGTVDALGVLTGAQL 664
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.411
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,602,586
Number of Sequences: 37866
Number of extensions: 901510
Number of successful extensions: 3382
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 3373
Number of HSP's gapped (non-prelim): 27
length of query: 496
length of database: 18,247,518
effective HSP length: 106
effective length of query: 390
effective length of database: 14,233,722
effective search space: 5551151580
effective search space used: 5551151580
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.