Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 31377806

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31377806 polymeric immunoglobulin receptor precursor [Homo
sapiens]
         (764 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31377806 polymeric immunoglobulin receptor precursor [Homo sa...  1540   0.0  
gi|172072602 Fc receptor, IgA, IgM, high affinity isoform 2 [Hom...   103   5e-22
gi|172072600 Fc receptor, IgA, IgM, high affinity isoform 1 [Hom...    99   1e-20
gi|117320515 Fc receptor, IgA, IgM, high affinity isoform 1 [Hom...    99   1e-20
gi|5729776 CD300C antigen [Homo sapiens]                               74   7e-13
gi|216547575 Fas apoptotic inhibitory molecule 3 isoform a [Homo...    72   3e-12
gi|4885641 Fas apoptotic inhibitory molecule 3 isoform a [Homo s...    72   3e-12
gi|56550061 leukocyte membrane antigen [Homo sapiens]                  71   3e-12
gi|31324530 CD300e molecule [Homo sapiens]                             63   9e-10
gi|153945782 natural cytotoxicity triggering receptor 2 [Homo sa...    62   2e-09
gi|21687218 CD300 molecule-like family member g [Homo sapiens]         59   2e-08
gi|38455398 NK inhibitory receptor precursor [Homo sapiens]            57   5e-08
gi|239756941 PREDICTED: similar to CD300C antigen [Homo sapiens]       55   2e-07
gi|239751445 PREDICTED: similar to CD300C antigen [Homo sapiens]       55   2e-07
gi|239745950 PREDICTED: similar to CD300C antigen [Homo sapiens]       55   2e-07
gi|169646348 CD300 molecule-like family member d [Homo sapiens]        55   2e-07
gi|38490688 immunoglobulin superfamily, member 10 [Homo sapiens]       55   2e-07
gi|9507203 triggering receptor expressed on myeloid cells 2 prec...    54   4e-07
gi|154759271 CD300 molecule-like family member b [Homo sapiens]        54   5e-07
gi|37700254 triggering receptor expressed on myeloid cells-like ...    52   2e-06
gi|58331253 obscurin, cytoskeletal calmodulin and titin-interact...    52   3e-06
gi|148833506 obscurin, cytoskeletal calmodulin and titin-interac...    52   3e-06
gi|55953135 immunoglobulin superfamily, member 3 isoform 2 [Homo...    50   8e-06
gi|118572606 hemicentin 1 [Homo sapiens]                               49   1e-05
gi|7657359 contactin 5 isoform long [Homo sapiens]                     47   7e-05
gi|28373129 contactin 5 isoform short [Homo sapiens]                   47   7e-05
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]                    47   9e-05
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]                    47   9e-05
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]                    47   9e-05
gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42...    46   1e-04

>gi|31377806 polymeric immunoglobulin receptor precursor [Homo
           sapiens]
          Length = 764

 Score = 1540 bits (3987), Expect = 0.0
 Identities = 764/764 (100%), Positives = 764/764 (100%)

Query: 1   MLLFVLTCLLAVFPAISTKSPIFGPEEVNSVEGNSVSITCYYPPTSVNRHTRKYWCRQGA 60
           MLLFVLTCLLAVFPAISTKSPIFGPEEVNSVEGNSVSITCYYPPTSVNRHTRKYWCRQGA
Sbjct: 1   MLLFVLTCLLAVFPAISTKSPIFGPEEVNSVEGNSVSITCYYPPTSVNRHTRKYWCRQGA 60

Query: 61  RGGCITLISSEGYVSSKYAGRANLTNFPENGTFVVNIAQLSQDDSGRYKCGLGINSRGLS 120
           RGGCITLISSEGYVSSKYAGRANLTNFPENGTFVVNIAQLSQDDSGRYKCGLGINSRGLS
Sbjct: 61  RGGCITLISSEGYVSSKYAGRANLTNFPENGTFVVNIAQLSQDDSGRYKCGLGINSRGLS 120

Query: 121 FDVSLEVSQGPGLLNDTKVYTVDLGRTVTINCPFKTENAQKRKSLYKQIGLYPVLVIDSS 180
           FDVSLEVSQGPGLLNDTKVYTVDLGRTVTINCPFKTENAQKRKSLYKQIGLYPVLVIDSS
Sbjct: 121 FDVSLEVSQGPGLLNDTKVYTVDLGRTVTINCPFKTENAQKRKSLYKQIGLYPVLVIDSS 180

Query: 181 GYVNPNYTGRIRLDIQGTGQLLFSVVINQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKP 240
           GYVNPNYTGRIRLDIQGTGQLLFSVVINQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKP
Sbjct: 181 GYVNPNYTGRIRLDIQGTGQLLFSVVINQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKP 240

Query: 241 EPELVYEDLRGSVTFHCALGPEVANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLN 300
           EPELVYEDLRGSVTFHCALGPEVANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLN
Sbjct: 241 EPELVYEDLRGSVTFHCALGPEVANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLN 300

Query: 301 PQDKDGSFSVVITGLRKEDAGRYLCGAHSDGQLQEGSPIQAWQLFVNEESTIPRSPTVVK 360
           PQDKDGSFSVVITGLRKEDAGRYLCGAHSDGQLQEGSPIQAWQLFVNEESTIPRSPTVVK
Sbjct: 301 PQDKDGSFSVVITGLRKEDAGRYLCGAHSDGQLQEGSPIQAWQLFVNEESTIPRSPTVVK 360

Query: 361 GVAGGSVAVLCPYNRKESKSIKYWCLWEGAQNGRCPLLVDSEGWVKAQYEGRLSLLEEPG 420
           GVAGGSVAVLCPYNRKESKSIKYWCLWEGAQNGRCPLLVDSEGWVKAQYEGRLSLLEEPG
Sbjct: 361 GVAGGSVAVLCPYNRKESKSIKYWCLWEGAQNGRCPLLVDSEGWVKAQYEGRLSLLEEPG 420

Query: 421 NGTFTVILNQLTSRDAGFYWCLTNGDTLWRTTVEIKIIEGEPNLKVPGNVTAVLGETLKV 480
           NGTFTVILNQLTSRDAGFYWCLTNGDTLWRTTVEIKIIEGEPNLKVPGNVTAVLGETLKV
Sbjct: 421 NGTFTVILNQLTSRDAGFYWCLTNGDTLWRTTVEIKIIEGEPNLKVPGNVTAVLGETLKV 480

Query: 481 PCHFPCKFSSYEKYWCKWNNTGCQALPSQDEGPSKAFVNCDENSRLVSLTLNLVTRADEG 540
           PCHFPCKFSSYEKYWCKWNNTGCQALPSQDEGPSKAFVNCDENSRLVSLTLNLVTRADEG
Sbjct: 481 PCHFPCKFSSYEKYWCKWNNTGCQALPSQDEGPSKAFVNCDENSRLVSLTLNLVTRADEG 540

Query: 541 WYWCGVKQGHFYGETAAVYVAVEERKAAGSRDVSLAKADAAPDEKVLDSGFREIENKAIQ 600
           WYWCGVKQGHFYGETAAVYVAVEERKAAGSRDVSLAKADAAPDEKVLDSGFREIENKAIQ
Sbjct: 541 WYWCGVKQGHFYGETAAVYVAVEERKAAGSRDVSLAKADAAPDEKVLDSGFREIENKAIQ 600

Query: 601 DPRLFAEEKAVADTRDQADGSRASVDSGSSEEQGGSSRALVSTLVPLGLVLAVGAVAVGV 660
           DPRLFAEEKAVADTRDQADGSRASVDSGSSEEQGGSSRALVSTLVPLGLVLAVGAVAVGV
Sbjct: 601 DPRLFAEEKAVADTRDQADGSRASVDSGSSEEQGGSSRALVSTLVPLGLVLAVGAVAVGV 660

Query: 661 ARARHRKNVDRVSIRSYRTDISMSDFENSREFGANDNMGASSITQETSLGGKEEFVATTE 720
           ARARHRKNVDRVSIRSYRTDISMSDFENSREFGANDNMGASSITQETSLGGKEEFVATTE
Sbjct: 661 ARARHRKNVDRVSIRSYRTDISMSDFENSREFGANDNMGASSITQETSLGGKEEFVATTE 720

Query: 721 STTETKEPKKAKRSSKEEAEMAYKDFLLQSSTVAAEAQDGPQEA 764
           STTETKEPKKAKRSSKEEAEMAYKDFLLQSSTVAAEAQDGPQEA
Sbjct: 721 STTETKEPKKAKRSSKEEAEMAYKDFLLQSSTVAAEAQDGPQEA 764


>gi|172072602 Fc receptor, IgA, IgM, high affinity isoform 2 [Homo
           sapiens]
          Length = 552

 Score =  103 bits (258), Expect = 5e-22
 Identities = 50/109 (45%), Positives = 68/109 (62%), Gaps = 1/109 (0%)

Query: 24  GPEEVNSVEGNSVSITCYYPPTSVNRHTRKYWCRQGA-RGGCITLISSEGYVSSKYAGRA 82
           G   V+   G +V+I C+Y P+SVNRH RKYWCR G  R  C T++S+  Y   +Y  R 
Sbjct: 86  GSRLVSGEPGGAVTIQCHYAPSSVNRHQRKYWCRLGPPRWICQTIVSTNQYTHHRYRDRV 145

Query: 83  NLTNFPENGTFVVNIAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGP 131
            LT+FP+ G FVV ++QLS DD G Y CG+G  +  L   ++L +S GP
Sbjct: 146 ALTDFPQRGLFVVRLSQLSPDDIGCYLCGIGSENNMLFLSMNLTISAGP 194



 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 38/121 (31%), Positives = 56/121 (46%), Gaps = 19/121 (15%)

Query: 331 GQLQEGSPIQAWQLFVNEESTIP-----RSPTVVKGVAGGSVAVLCPY-----NRKESKS 380
           G L+  SP+  W+    EES+       +   +V G  GG+V + C Y     NR + K 
Sbjct: 62  GTLRPSSPL-CWR----EESSFAAPNSLKGSRLVSGEPGGAVTIQCHYAPSSVNRHQRK- 115

Query: 381 IKYWCLWEGAQNGRCPLLVDSEGWVKAQYEGRLSLLEEPGNGTFTVILNQLTSRDAGFYW 440
             YWC   G     C  +V +  +   +Y  R++L + P  G F V L+QL+  D G Y 
Sbjct: 116 --YWCRL-GPPRWICQTIVSTNQYTHHRYRDRVALTDFPQRGLFVVRLSQLSPDDIGCYL 172

Query: 441 C 441
           C
Sbjct: 173 C 173



 Score = 38.5 bits (88), Expect = 0.024
 Identities = 32/116 (27%), Positives = 47/116 (40%), Gaps = 13/116 (11%)

Query: 244 LVYEDLRGSVTFHCALGPEVAN--VAKFLCRQSSGE-NCDVVVNTLGKRAPAFEGRILLN 300
           LV  +  G+VT  C   P   N    K+ CR       C  +V+T       +  R+ L 
Sbjct: 89  LVSGEPGGAVTIQCHYAPSSVNRHQRKYWCRLGPPRWICQTIVSTNQYTHHRYRDRVALT 148

Query: 301 PQDKDGSFSVVITGLRKEDAGRYLCGAHSDGQLQEGSPIQAWQLFVNEESTIPRSP 356
              + G F V ++ L  +D G YLCG  S+  +          LF++   TI   P
Sbjct: 149 DFPQRGLFVVRLSQLSPDDIGCYLCGIGSENNM----------LFLSMNLTISAGP 194



 Score = 35.8 bits (81), Expect = 0.15
 Identities = 28/103 (27%), Positives = 47/103 (45%), Gaps = 9/103 (8%)

Query: 131 PGLLNDTKVYTVDLGRTVTINCPFKTENAQKRKSLYKQIGLYPV-----LVIDSSGYVNP 185
           P  L  +++ + + G  VTI C +   +  + +  Y    L P       ++ ++ Y + 
Sbjct: 81  PNSLKGSRLVSGEPGGAVTIQCHYAPSSVNRHQRKY-WCRLGPPRWICQTIVSTNQYTHH 139

Query: 186 NYTGRIRL-DIQGTGQLLFSVVINQLRLSDAGQYLCQAGDDSN 227
            Y  R+ L D    G  LF V ++QL   D G YLC  G ++N
Sbjct: 140 RYRDRVALTDFPQRG--LFVVRLSQLSPDDIGCYLCGIGSENN 180


>gi|172072600 Fc receptor, IgA, IgM, high affinity isoform 1 [Homo
           sapiens]
          Length = 265

 Score = 99.4 bits (246), Expect = 1e-20
 Identities = 48/106 (45%), Positives = 66/106 (62%), Gaps = 1/106 (0%)

Query: 24  GPEEVNSVEGNSVSITCYYPPTSVNRHTRKYWCRQGA-RGGCITLISSEGYVSSKYAGRA 82
           G   V+   G +V+I C+Y P+SVNRH RKYWCR G  R  C T++S+  Y   +Y  R 
Sbjct: 111 GSRLVSGEPGGAVTIQCHYAPSSVNRHQRKYWCRLGPPRWICQTIVSTNQYTHHRYRDRV 170

Query: 83  NLTNFPENGTFVVNIAQLSQDDSGRYKCGLGINSRGLSFDVSLEVS 128
            LT+FP+ G FVV ++QLS DD G Y CG+G  +  L   ++L +S
Sbjct: 171 ALTDFPQRGLFVVRLSQLSPDDIGCYLCGIGSENNMLFLSMNLTIS 216



 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 38/121 (31%), Positives = 56/121 (46%), Gaps = 19/121 (15%)

Query: 331 GQLQEGSPIQAWQLFVNEESTIP-----RSPTVVKGVAGGSVAVLCPY-----NRKESKS 380
           G L+  SP+  W+    EES+       +   +V G  GG+V + C Y     NR + K 
Sbjct: 87  GTLRPSSPL-CWR----EESSFAAPNSLKGSRLVSGEPGGAVTIQCHYAPSSVNRHQRK- 140

Query: 381 IKYWCLWEGAQNGRCPLLVDSEGWVKAQYEGRLSLLEEPGNGTFTVILNQLTSRDAGFYW 440
             YWC   G     C  +V +  +   +Y  R++L + P  G F V L+QL+  D G Y 
Sbjct: 141 --YWCRL-GPPRWICQTIVSTNQYTHHRYRDRVALTDFPQRGLFVVRLSQLSPDDIGCYL 197

Query: 441 C 441
           C
Sbjct: 198 C 198



 Score = 38.1 bits (87), Expect = 0.031
 Identities = 27/93 (29%), Positives = 40/93 (43%), Gaps = 3/93 (3%)

Query: 244 LVYEDLRGSVTFHCALGPEVAN--VAKFLCRQSSGE-NCDVVVNTLGKRAPAFEGRILLN 300
           LV  +  G+VT  C   P   N    K+ CR       C  +V+T       +  R+ L 
Sbjct: 114 LVSGEPGGAVTIQCHYAPSSVNRHQRKYWCRLGPPRWICQTIVSTNQYTHHRYRDRVALT 173

Query: 301 PQDKDGSFSVVITGLRKEDAGRYLCGAHSDGQL 333
              + G F V ++ L  +D G YLCG  S+  +
Sbjct: 174 DFPQRGLFVVRLSQLSPDDIGCYLCGIGSENNM 206



 Score = 37.0 bits (84), Expect = 0.069
 Identities = 39/162 (24%), Positives = 71/162 (43%), Gaps = 28/162 (17%)

Query: 131 PGLLNDTKVYTVDLGRTVTINCPFKTENAQKRKSLYKQIGLYPV-----LVIDSSGYVNP 185
           P  L  +++ + + G  VTI C +   +  + +  Y    L P       ++ ++ Y + 
Sbjct: 106 PNSLKGSRLVSGEPGGAVTIQCHYAPSSVNRHQRKY-WCRLGPPRWICQTIVSTNQYTHH 164

Query: 186 NYTGRIRL-DIQGTGQLLFSVVINQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKPEPEL 244
            Y  R+ L D    G  LF V ++QL   D G YLC  G ++N    + +L +      +
Sbjct: 165 RYRDRVALTDFPQRG--LFVVRLSQLSPDDIGCYLCGIGSENNMLFLSMNLTI----SAV 218

Query: 245 VYEDLRGSVTFHCALGPEVANV---------AKFLCRQSSGE 277
           +++ ++       ALGP + ++           F C+ SSGE
Sbjct: 219 LFQKMK------AALGPWLLSLPCWPCLCLWLWFYCKGSSGE 254


>gi|117320515 Fc receptor, IgA, IgM, high affinity isoform 1 [Homo
           sapiens]
          Length = 265

 Score = 99.4 bits (246), Expect = 1e-20
 Identities = 48/106 (45%), Positives = 66/106 (62%), Gaps = 1/106 (0%)

Query: 24  GPEEVNSVEGNSVSITCYYPPTSVNRHTRKYWCRQGA-RGGCITLISSEGYVSSKYAGRA 82
           G   V+   G +V+I C+Y P+SVNRH RKYWCR G  R  C T++S+  Y   +Y  R 
Sbjct: 111 GSRLVSGEPGGAVTIQCHYAPSSVNRHQRKYWCRLGPPRWICQTIVSTNQYTHHRYRDRV 170

Query: 83  NLTNFPENGTFVVNIAQLSQDDSGRYKCGLGINSRGLSFDVSLEVS 128
            LT+FP+ G FVV ++QLS DD G Y CG+G  +  L   ++L +S
Sbjct: 171 ALTDFPQRGLFVVRLSQLSPDDIGCYLCGIGSENNMLFLSMNLTIS 216



 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 38/121 (31%), Positives = 56/121 (46%), Gaps = 19/121 (15%)

Query: 331 GQLQEGSPIQAWQLFVNEESTIP-----RSPTVVKGVAGGSVAVLCPY-----NRKESKS 380
           G L+  SP+  W+    EES+       +   +V G  GG+V + C Y     NR + K 
Sbjct: 87  GTLRPSSPL-CWR----EESSFAAPNSLKGSRLVSGEPGGAVTIQCHYAPSSVNRHQRK- 140

Query: 381 IKYWCLWEGAQNGRCPLLVDSEGWVKAQYEGRLSLLEEPGNGTFTVILNQLTSRDAGFYW 440
             YWC   G     C  +V +  +   +Y  R++L + P  G F V L+QL+  D G Y 
Sbjct: 141 --YWCRL-GPPRWICQTIVSTNQYTHHRYRDRVALTDFPQRGLFVVRLSQLSPDDIGCYL 197

Query: 441 C 441
           C
Sbjct: 198 C 198



 Score = 38.1 bits (87), Expect = 0.031
 Identities = 27/93 (29%), Positives = 40/93 (43%), Gaps = 3/93 (3%)

Query: 244 LVYEDLRGSVTFHCALGPEVAN--VAKFLCRQSSGE-NCDVVVNTLGKRAPAFEGRILLN 300
           LV  +  G+VT  C   P   N    K+ CR       C  +V+T       +  R+ L 
Sbjct: 114 LVSGEPGGAVTIQCHYAPSSVNRHQRKYWCRLGPPRWICQTIVSTNQYTHHRYRDRVALT 173

Query: 301 PQDKDGSFSVVITGLRKEDAGRYLCGAHSDGQL 333
              + G F V ++ L  +D G YLCG  S+  +
Sbjct: 174 DFPQRGLFVVRLSQLSPDDIGCYLCGIGSENNM 206



 Score = 37.0 bits (84), Expect = 0.069
 Identities = 39/162 (24%), Positives = 71/162 (43%), Gaps = 28/162 (17%)

Query: 131 PGLLNDTKVYTVDLGRTVTINCPFKTENAQKRKSLYKQIGLYPV-----LVIDSSGYVNP 185
           P  L  +++ + + G  VTI C +   +  + +  Y    L P       ++ ++ Y + 
Sbjct: 106 PNSLKGSRLVSGEPGGAVTIQCHYAPSSVNRHQRKY-WCRLGPPRWICQTIVSTNQYTHH 164

Query: 186 NYTGRIRL-DIQGTGQLLFSVVINQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKPEPEL 244
            Y  R+ L D    G  LF V ++QL   D G YLC  G ++N    + +L +      +
Sbjct: 165 RYRDRVALTDFPQRG--LFVVRLSQLSPDDIGCYLCGIGSENNMLFLSMNLTI----SAV 218

Query: 245 VYEDLRGSVTFHCALGPEVANV---------AKFLCRQSSGE 277
           +++ ++       ALGP + ++           F C+ SSGE
Sbjct: 219 LFQKMK------AALGPWLLSLPCWPCLCLWLWFYCKGSSGE 254


>gi|5729776 CD300C antigen [Homo sapiens]
          Length = 224

 Score = 73.6 bits (179), Expect = 7e-13
 Identities = 47/136 (34%), Positives = 65/136 (47%), Gaps = 13/136 (9%)

Query: 356 PTVVKGVAGGSVAVLCPYNRKESKSIKYWCLWEGAQNGRCPLLVDSEGWVKAQYEGRLSL 415
           P  V G  GGS++V C Y ++     K+WC     Q  RC  +V+++G    +  GR+S+
Sbjct: 28  PMTVAGPVGGSLSVQCRYEKEHRTLNKFWC--RPPQILRCDKIVETKGSA-GKRNGRVSI 84

Query: 416 LEEPGNGTFTVILNQLTSRDAGFYWCLTNGDTLWRTTVEIKIIEGEPNLKVPGNVTA--- 472
            + P N +FTV L  LT  DAG YWC    DT W       I+E E ++   G  TA   
Sbjct: 85  RDSPANLSFTVTLENLTEEDAGTYWC--GVDTPWLRDFHDPIVEVEVSVFPAGTTTASSP 142

Query: 473 -----VLGETLKVPCH 483
                  G   K+P H
Sbjct: 143 QSSMGTSGPPTKLPVH 158



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 28/92 (30%), Positives = 48/92 (52%), Gaps = 3/92 (3%)

Query: 21  PIFGPEEVNSVEGNSVSITCYYPPTSVNRHTRKYWCRQGARGGCITLISSEGYVSSKYAG 80
           P+  P  V    G S+S+ C Y     +R   K+WCR      C  ++ ++G  + K  G
Sbjct: 24  PLSHPMTVAGPVGGSLSVQCRYEKE--HRTLNKFWCRPPQILRCDKIVETKGS-AGKRNG 80

Query: 81  RANLTNFPENGTFVVNIAQLSQDDSGRYKCGL 112
           R ++ + P N +F V +  L+++D+G Y CG+
Sbjct: 81  RVSIRDSPANLSFTVTLENLTEEDAGTYWCGV 112



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 37/124 (29%), Positives = 53/124 (42%), Gaps = 2/124 (1%)

Query: 242 PELVYEDLRGSVTFHCALGPEVANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLNP 301
           P  V   + GS++  C    E   + KF CR      CD +V T G  A    GR+ +  
Sbjct: 28  PMTVAGPVGGSLSVQCRYEKEHRTLNKFWCRPPQILRCDKIVETKGS-AGKRNGRVSIRD 86

Query: 302 QDKDGSFSVVITGLRKEDAGRYLCGAHSDGQLQEGSPIQAWQLFV-NEESTIPRSPTVVK 360
              + SF+V +  L +EDAG Y CG  +        PI   ++ V    +T   SP    
Sbjct: 87  SPANLSFTVTLENLTEEDAGTYWCGVDTPWLRDFHDPIVEVEVSVFPAGTTTASSPQSSM 146

Query: 361 GVAG 364
           G +G
Sbjct: 147 GTSG 150



 Score = 38.9 bits (89), Expect = 0.018
 Identities = 27/104 (25%), Positives = 47/104 (45%), Gaps = 6/104 (5%)

Query: 449 WRTT-VEIKIIEGEPNLKVPGNVTAVLGETLKVPCHFPCKFSSYEKYWCKWNN-TGCQAL 506
           WR++ + + ++ G   L  P  V   +G +L V C +  +  +  K+WC+      C  +
Sbjct: 9   WRSSALLLLLVPGYFPLSHPMTVAGPVGGSLSVQCRYEKEHRTLNKFWCRPPQILRCDKI 68

Query: 507 --PSQDEGPSKAFVNCDENSRLVSLTLNL--VTRADEGWYWCGV 546
                  G     V+  ++   +S T+ L  +T  D G YWCGV
Sbjct: 69  VETKGSAGKRNGRVSIRDSPANLSFTVTLENLTEEDAGTYWCGV 112


>gi|216547575 Fas apoptotic inhibitory molecule 3 isoform a [Homo
           sapiens]
          Length = 390

 Score = 71.6 bits (174), Expect = 3e-12
 Identities = 42/117 (35%), Positives = 62/117 (52%), Gaps = 6/117 (5%)

Query: 13  FPAISTKSPIFGPEEVNSVEGNSVSITCYYPPTSVNRHTRKYWCRQGARGG-CITLISSE 71
           F  +S    I    +V    G SV+I C  P      H R Y CR+ A  G C T++S+ 
Sbjct: 10  FLPVSGALRILPEVKVEGELGGSVTIKCPLP----EMHVRIYLCREMAGSGTCGTVVSTT 65

Query: 72  GYVSSKYAGRANLTNFPENGTFVVNIAQLSQDDSGRYKCGLGINS-RGLSFDVSLEV 127
            ++ ++Y GR  L  +P    F+V + QL++ DSG Y CG G+N+ RG +  V+L V
Sbjct: 66  NFIKAEYKGRVTLKQYPRKNLFLVEVTQLTESDSGVYACGAGMNTDRGKTQKVTLNV 122



 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 29/83 (34%), Positives = 46/83 (55%), Gaps = 3/83 (3%)

Query: 359 VKGVAGGSVAVLCPYNRKESKSIKYWCLWEGAQNGRCPLLVDSEGWVKAQYEGRLSLLEE 418
           V+G  GGSV + CP        ++ +   E A +G C  +V +  ++KA+Y+GR++L + 
Sbjct: 25  VEGELGGSVTIKCPLPEMH---VRIYLCREMAGSGTCGTVVSTTNFIKAEYKGRVTLKQY 81

Query: 419 PGNGTFTVILNQLTSRDAGFYWC 441
           P    F V + QLT  D+G Y C
Sbjct: 82  PRKNLFLVEVTQLTESDSGVYAC 104



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 34/88 (38%), Positives = 49/88 (55%), Gaps = 4/88 (4%)

Query: 242 PELVYE-DLRGSVTFHCALGPEVANVAKFLCRQSSGEN-CDVVVNTLGKRAPAFEGRILL 299
           PE+  E +L GSVT  C L PE+ +V  +LCR+ +G   C  VV+T       ++GR+ L
Sbjct: 21  PEVKVEGELGGSVTIKCPL-PEM-HVRIYLCREMAGSGTCGTVVSTTNFIKAEYKGRVTL 78

Query: 300 NPQDKDGSFSVVITGLRKEDAGRYLCGA 327
               +   F V +T L + D+G Y CGA
Sbjct: 79  KQYPRKNLFLVEVTQLTESDSGVYACGA 106



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 34/108 (31%), Positives = 54/108 (50%), Gaps = 6/108 (5%)

Query: 125 LEVSQGPGLLNDTKVYTVDLGRTVTINCPFKTENAQKRKSLYKQIGLYPVL--VIDSSGY 182
           L VS    +L + KV   +LG +VTI CP    +   R  L +++        V+ ++ +
Sbjct: 11  LPVSGALRILPEVKVEG-ELGGSVTIKCPLPEMHV--RIYLCREMAGSGTCGTVVSTTNF 67

Query: 183 VNPNYTGRIRLDIQGTGQLLFSVVINQLRLSDAGQYLCQAGDDSNSNK 230
           +   Y GR+ L  Q   + LF V + QL  SD+G Y C AG +++  K
Sbjct: 68  IKAEYKGRVTLK-QYPRKNLFLVEVTQLTESDSGVYACGAGMNTDRGK 114


>gi|4885641 Fas apoptotic inhibitory molecule 3 isoform a [Homo
           sapiens]
          Length = 390

 Score = 71.6 bits (174), Expect = 3e-12
 Identities = 42/117 (35%), Positives = 62/117 (52%), Gaps = 6/117 (5%)

Query: 13  FPAISTKSPIFGPEEVNSVEGNSVSITCYYPPTSVNRHTRKYWCRQGARGG-CITLISSE 71
           F  +S    I    +V    G SV+I C  P      H R Y CR+ A  G C T++S+ 
Sbjct: 10  FLPVSGALRILPEVKVEGELGGSVTIKCPLP----EMHVRIYLCREMAGSGTCGTVVSTT 65

Query: 72  GYVSSKYAGRANLTNFPENGTFVVNIAQLSQDDSGRYKCGLGINS-RGLSFDVSLEV 127
            ++ ++Y GR  L  +P    F+V + QL++ DSG Y CG G+N+ RG +  V+L V
Sbjct: 66  NFIKAEYKGRVTLKQYPRKNLFLVEVTQLTESDSGVYACGAGMNTDRGKTQKVTLNV 122



 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 29/83 (34%), Positives = 46/83 (55%), Gaps = 3/83 (3%)

Query: 359 VKGVAGGSVAVLCPYNRKESKSIKYWCLWEGAQNGRCPLLVDSEGWVKAQYEGRLSLLEE 418
           V+G  GGSV + CP        ++ +   E A +G C  +V +  ++KA+Y+GR++L + 
Sbjct: 25  VEGELGGSVTIKCPLPEMH---VRIYLCREMAGSGTCGTVVSTTNFIKAEYKGRVTLKQY 81

Query: 419 PGNGTFTVILNQLTSRDAGFYWC 441
           P    F V + QLT  D+G Y C
Sbjct: 82  PRKNLFLVEVTQLTESDSGVYAC 104



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 34/88 (38%), Positives = 49/88 (55%), Gaps = 4/88 (4%)

Query: 242 PELVYE-DLRGSVTFHCALGPEVANVAKFLCRQSSGEN-CDVVVNTLGKRAPAFEGRILL 299
           PE+  E +L GSVT  C L PE+ +V  +LCR+ +G   C  VV+T       ++GR+ L
Sbjct: 21  PEVKVEGELGGSVTIKCPL-PEM-HVRIYLCREMAGSGTCGTVVSTTNFIKAEYKGRVTL 78

Query: 300 NPQDKDGSFSVVITGLRKEDAGRYLCGA 327
               +   F V +T L + D+G Y CGA
Sbjct: 79  KQYPRKNLFLVEVTQLTESDSGVYACGA 106



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 34/108 (31%), Positives = 54/108 (50%), Gaps = 6/108 (5%)

Query: 125 LEVSQGPGLLNDTKVYTVDLGRTVTINCPFKTENAQKRKSLYKQIGLYPVL--VIDSSGY 182
           L VS    +L + KV   +LG +VTI CP    +   R  L +++        V+ ++ +
Sbjct: 11  LPVSGALRILPEVKVEG-ELGGSVTIKCPLPEMHV--RIYLCREMAGSGTCGTVVSTTNF 67

Query: 183 VNPNYTGRIRLDIQGTGQLLFSVVINQLRLSDAGQYLCQAGDDSNSNK 230
           +   Y GR+ L  Q   + LF V + QL  SD+G Y C AG +++  K
Sbjct: 68  IKAEYKGRVTLK-QYPRKNLFLVEVTQLTESDSGVYACGAGMNTDRGK 114


>gi|56550061 leukocyte membrane antigen [Homo sapiens]
          Length = 299

 Score = 71.2 bits (173), Expect = 3e-12
 Identities = 43/126 (34%), Positives = 63/126 (50%), Gaps = 11/126 (8%)

Query: 359 VKGVAGGSVAVLCPYNRKESKSIKYWCLWEGAQNGRCPLLVDSEGWVKAQYEGRLSLLEE 418
           V G  GGS++V CPY ++     KYWC     Q   C  +V+++G    +  GR+S+ + 
Sbjct: 24  VAGPVGGSLSVQCPYEKEHRTLNKYWC--RPPQIFLCDKIVETKGSA-GKRNGRVSIRDS 80

Query: 419 PGNGTFTVILNQLTSRDAGFYWCLTNGDTLWRTTVEIKIIEGEPNL------KVPGNVTA 472
           P N +FTV L  LT  DAG YWC    DT W       ++E E ++        P ++TA
Sbjct: 81  PANLSFTVTLENLTEEDAGTYWC--GVDTPWLRDFHDPVVEVEVSVFPASTSMTPASITA 138

Query: 473 VLGETL 478
               T+
Sbjct: 139 AKTSTI 144



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 45/156 (28%), Positives = 72/156 (46%), Gaps = 17/156 (10%)

Query: 1   MLLFVLTCLLAVFPAISTKSPIFGPEEVNSVEGNSVSITCYYPPTSVNRHTRKYWCRQGA 60
           +LL+V  C      A+S    + GP       G S+S+ C Y     +R   KYWCR   
Sbjct: 8   LLLWVPGCF-----ALSKCRTVAGPV------GGSLSVQCPYEKE--HRTLNKYWCRPPQ 54

Query: 61  RGGCITLISSEGYVSSKYAGRANLTNFPENGTFVVNIAQLSQDDSGRYKCGLGINSRGLS 120
              C  ++ ++G  + K  GR ++ + P N +F V +  L+++D+G Y CG+        
Sbjct: 55  IFLCDKIVETKGS-AGKRNGRVSIRDSPANLSFTVTLENLTEEDAGTYWCGVDTPWLRDF 113

Query: 121 FD--VSLEVSQGPGLLNDTKVYTVDLGRTVTINCPF 154
            D  V +EVS  P   + T   ++   +T TI   F
Sbjct: 114 HDPVVEVEVSVFPASTSMTPA-SITAAKTSTITTAF 148



 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 34/112 (30%), Positives = 49/112 (43%), Gaps = 3/112 (2%)

Query: 251 GSVTFHCALGPEVANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLNPQDKDGSFSV 310
           GS++  C    E   + K+ CR      CD +V T G  A    GR+ +     + SF+V
Sbjct: 30  GSLSVQCPYEKEHRTLNKYWCRPPQIFLCDKIVETKGS-AGKRNGRVSIRDSPANLSFTV 88

Query: 311 VITGLRKEDAGRYLCGAHSDGQLQEGSPIQAWQLFVNEEST--IPRSPTVVK 360
            +  L +EDAG Y CG  +        P+   ++ V   ST   P S T  K
Sbjct: 89  TLENLTEEDAGTYWCGVDTPWLRDFHDPVVEVEVSVFPASTSMTPASITAAK 140



 Score = 35.0 bits (79), Expect = 0.26
 Identities = 23/82 (28%), Positives = 36/82 (43%), Gaps = 5/82 (6%)

Query: 470 VTAVLGETLKVPCHFPCKFSSYEKYWCKWNNTG-CQALPSQ--DEGPSKAFVNCDENSRL 526
           V   +G +L V C +  +  +  KYWC+      C  +       G     V+  ++   
Sbjct: 24  VAGPVGGSLSVQCPYEKEHRTLNKYWCRPPQIFLCDKIVETKGSAGKRNGRVSIRDSPAN 83

Query: 527 VSLTLNL--VTRADEGWYWCGV 546
           +S T+ L  +T  D G YWCGV
Sbjct: 84  LSFTVTLENLTEEDAGTYWCGV 105


>gi|31324530 CD300e molecule [Homo sapiens]
          Length = 205

 Score = 63.2 bits (152), Expect = 9e-10
 Identities = 34/94 (36%), Positives = 46/94 (48%), Gaps = 4/94 (4%)

Query: 356 PTVVKGVAGGSVAVLCPYNRKESKSIKYWCLWEGAQNGRCPLLVDSEGWVKAQYEGRLSL 415
           P  V G AG S+ V C Y        KYWC   G  +  C  +V+++G  K +  GR+S+
Sbjct: 21  PGSVTGTAGDSLTVWCQYESMYKGYNKYWC--RGQYDTSCESIVETKGEEKVERNGRVSI 78

Query: 416 LEEPGNGTFTVILNQLTSRDAGFYWCLTNGDTLW 449
            + P    FTV +  L   DAG YWC     T+W
Sbjct: 79  RDHPEALAFTVTMQNLNEDDAGSYWCKI--QTVW 110



 Score = 56.6 bits (135), Expect = 8e-08
 Identities = 27/87 (31%), Positives = 46/87 (52%), Gaps = 2/87 (2%)

Query: 24  GPEEVNSVEGNSVSITCYYPPTSVNRHTRKYWCRQGARGGCITLISSEGYVSSKYAGRAN 83
           GP  V    G+S+++ C Y   S+ +   KYWCR      C +++ ++G    +  GR +
Sbjct: 20  GPGSVTGTAGDSLTVWCQYE--SMYKGYNKYWCRGQYDTSCESIVETKGEEKVERNGRVS 77

Query: 84  LTNFPENGTFVVNIAQLSQDDSGRYKC 110
           + + PE   F V +  L++DD+G Y C
Sbjct: 78  IRDHPEALAFTVTMQNLNEDDAGSYWC 104



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 24/96 (25%), Positives = 46/96 (47%), Gaps = 6/96 (6%)

Query: 458 IEGEPNLKVPGNVTAVLGETLKVPCHFPCKFSSYEKYWCKWN-NTGCQAL-----PSQDE 511
           + G  +L  PG+VT   G++L V C +   +  Y KYWC+   +T C+++       + E
Sbjct: 12  LSGCLSLTGPGSVTGTAGDSLTVWCQYESMYKGYNKYWCRGQYDTSCESIVETKGEEKVE 71

Query: 512 GPSKAFVNCDENSRLVSLTLNLVTRADEGWYWCGVK 547
              +  +     +   ++T+  +   D G YWC ++
Sbjct: 72  RNGRVSIRDHPEALAFTVTMQNLNEDDAGSYWCKIQ 107



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 28/108 (25%), Positives = 47/108 (43%), Gaps = 2/108 (1%)

Query: 252 SVTFHCALGPEVANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLNPQDKDGSFSVV 311
           S+T  C          K+ CR     +C+ +V T G+      GR+ +    +  +F+V 
Sbjct: 31  SLTVWCQYESMYKGYNKYWCRGQYDTSCESIVETKGEEKVERNGRVSIRDHPEALAFTVT 90

Query: 312 ITGLRKEDAGRYLCGAHSDGQLQEGS--PIQAWQLFVNEESTIPRSPT 357
           +  L ++DAG Y C   +   L   S  P    +++V+   T PR  T
Sbjct: 91  MQNLNEDDAGSYWCKIQTVWVLDSWSRDPSDLVRVYVSPAITTPRRTT 138


>gi|153945782 natural cytotoxicity triggering receptor 2 [Homo
           sapiens]
          Length = 276

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 33/108 (30%), Positives = 57/108 (52%), Gaps = 4/108 (3%)

Query: 3   LFVLTCLLAVFPAISTKSPIFGPEEVNSVEGNSVSITCYYPPTSVNRHTRKYWCRQGARG 62
           L  L  LL +FP    +S     + + SV G ++++ C YPPT  + + +K WC++ +  
Sbjct: 6   LHPLLLLLLLFPGSQAQSKA---QVLQSVAGQTLTVRCQYPPTG-SLYEKKGWCKEASAL 61

Query: 63  GCITLISSEGYVSSKYAGRANLTNFPENGTFVVNIAQLSQDDSGRYKC 110
            CI L++S    +  +  R  + + P+ G F V +  L ++DSG Y C
Sbjct: 62  VCIRLVTSSKPRTMAWTSRFTIWDDPDAGFFTVTMTDLREEDSGHYWC 109



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 3/85 (3%)

Query: 358 VVKGVAGGSVAVLCPYNRKESK-SIKYWCLWEGAQNGRCPLLVDSEGWVKAQYEGRLSLL 416
           V++ VAG ++ V C Y    S    K WC  + A    C  LV S       +  R ++ 
Sbjct: 27  VLQSVAGQTLTVRCQYPPTGSLYEKKGWC--KEASALVCIRLVTSSKPRTMAWTSRFTIW 84

Query: 417 EEPGNGTFTVILNQLTSRDAGFYWC 441
           ++P  G FTV +  L   D+G YWC
Sbjct: 85  DDPDAGFFTVTMTDLREEDSGHYWC 109



 Score = 36.6 bits (83), Expect = 0.090
 Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 7/82 (8%)

Query: 472 AVLGETLKVPCHFPCKFSSYEKY-WCKWNNT-GCQALPSQDEGPSKAFVN-----CDENS 524
           +V G+TL V C +P   S YEK  WCK  +   C  L +  +  + A+ +      D ++
Sbjct: 30  SVAGQTLTVRCQYPPTGSLYEKKGWCKEASALVCIRLVTSSKPRTMAWTSRFTIWDDPDA 89

Query: 525 RLVSLTLNLVTRADEGWYWCGV 546
              ++T+  +   D G YWC +
Sbjct: 90  GFFTVTMTDLREEDSGHYWCRI 111



 Score = 36.2 bits (82), Expect = 0.12
 Identities = 18/55 (32%), Positives = 29/55 (52%)

Query: 271 CRQSSGENCDVVVNTLGKRAPAFEGRILLNPQDKDGSFSVVITGLRKEDAGRYLC 325
           C+++S   C  +V +   R  A+  R  +      G F+V +T LR+ED+G Y C
Sbjct: 55  CKEASALVCIRLVTSSKPRTMAWTSRFTIWDDPDAGFFTVTMTDLREEDSGHYWC 109


>gi|21687218 CD300 molecule-like family member g [Homo sapiens]
          Length = 332

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 36/110 (32%), Positives = 54/110 (49%), Gaps = 4/110 (3%)

Query: 24  GPEEVNSVEGNSVSITCYYPPTSVNRHTRKYWCRQGAR--GGCITLISSEGYVSSKYAGR 81
           GPEE++  EG++VS+ C Y      R  RKYWCR+G      C   I +E        GR
Sbjct: 21  GPEEISGFEGDTVSLQCTYREEL--RDHRKYWCRKGGILFSRCSGTIYAEEEGQETMKGR 78

Query: 82  ANLTNFPENGTFVVNIAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGP 131
            ++ +  +  + +V +  L+  D+G Y CG+       S  +SL V  GP
Sbjct: 79  VSIRDSRQELSLIVTLWNLTLQDAGEYWCGVEKRGPDESLLISLFVFPGP 128



 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 27/86 (31%), Positives = 41/86 (47%)

Query: 356 PTVVKGVAGGSVAVLCPYNRKESKSIKYWCLWEGAQNGRCPLLVDSEGWVKAQYEGRLSL 415
           P  + G  G +V++ C Y  +     KYWC   G    RC   + +E   +   +GR+S+
Sbjct: 22  PEEISGFEGDTVSLQCTYREELRDHRKYWCRKGGILFSRCSGTIYAEEEGQETMKGRVSI 81

Query: 416 LEEPGNGTFTVILNQLTSRDAGFYWC 441
            +     +  V L  LT +DAG YWC
Sbjct: 82  RDSRQELSLIVTLWNLTLQDAGEYWC 107



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 26/100 (26%), Positives = 52/100 (52%), Gaps = 8/100 (8%)

Query: 457 IIEGEPNLKVPGNVTAVLGETLKVPCHFPCKFSSYEKYWCKWNN---TGCQ-ALPSQDEG 512
           ++ G   L+ P  ++   G+T+ + C +  +   + KYWC+      + C   + +++EG
Sbjct: 12  LLPGYEALEGPEEISGFEGDTVSLQCTYREELRDHRKYWCRKGGILFSRCSGTIYAEEEG 71

Query: 513 PS--KAFVNCDENSRLVSLTLNL--VTRADEGWYWCGVKQ 548
               K  V+  ++ + +SL + L  +T  D G YWCGV++
Sbjct: 72  QETMKGRVSIRDSRQELSLIVTLWNLTLQDAGEYWCGVEK 111



 Score = 34.3 bits (77), Expect = 0.45
 Identities = 19/82 (23%), Positives = 34/82 (41%), Gaps = 2/82 (2%)

Query: 252 SVTFHCALGPEVANVAKFLCRQSS--GENCDVVVNTLGKRAPAFEGRILLNPQDKDGSFS 309
           +V+  C    E+ +  K+ CR+       C   +    +     +GR+ +    ++ S  
Sbjct: 32  TVSLQCTYREELRDHRKYWCRKGGILFSRCSGTIYAEEEGQETMKGRVSIRDSRQELSLI 91

Query: 310 VVITGLRKEDAGRYLCGAHSDG 331
           V +  L  +DAG Y CG    G
Sbjct: 92  VTLWNLTLQDAGEYWCGVEKRG 113


>gi|38455398 NK inhibitory receptor precursor [Homo sapiens]
          Length = 290

 Score = 57.4 bits (137), Expect = 5e-08
 Identities = 31/86 (36%), Positives = 42/86 (48%), Gaps = 2/86 (2%)

Query: 356 PTVVKGVAGGSVAVLCPYNRKESKSIKYWCLWEGAQNGRCPLLVDSEGWVKAQYEGRLSL 415
           PT V G+  GS+ V C Y       +K+WC   GA    C +LV + G  +     R+S+
Sbjct: 25  PTTVNGLERGSLTVQCVYRSGWETYLKWWC--RGAIWRDCKILVKTSGSEQEVKRDRVSI 82

Query: 416 LEEPGNGTFTVILNQLTSRDAGFYWC 441
            +   N TFTV +  L   DA  YWC
Sbjct: 83  KDNQKNRTFTVTMEDLMKTDADTYWC 108



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 37/137 (27%), Positives = 56/137 (40%), Gaps = 2/137 (1%)

Query: 1   MLLFVLTCLLAVFPAISTKSPIFGPEEVNSVEGNSVSITCYYPPTSVNRHTRKYWCRQGA 60
           M L  L  LL      S  + I GP  VN +E  S+++ C Y   S      K+WCR   
Sbjct: 1   MPLLTLYLLLFWLSGYSIVTQITGPTTVNGLERGSLTVQCVY--RSGWETYLKWWCRGAI 58

Query: 61  RGGCITLISSEGYVSSKYAGRANLTNFPENGTFVVNIAQLSQDDSGRYKCGLGINSRGLS 120
              C  L+ + G        R ++ +  +N TF V +  L + D+  Y CG+      L 
Sbjct: 59  WRDCKILVKTSGSEQEVKRDRVSIKDNQKNRTFTVTMEDLMKTDADTYWCGIEKTGNDLG 118

Query: 121 FDVSLEVSQGPGLLNDT 137
             V + +   P    +T
Sbjct: 119 VTVQVTIDPAPVTQEET 135



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 24/82 (29%), Positives = 36/82 (43%)

Query: 250 RGSVTFHCALGPEVANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLNPQDKDGSFS 309
           RGS+T  C          K+ CR +   +C ++V T G        R+ +    K+ +F+
Sbjct: 33  RGSLTVQCVYRSGWETYLKWWCRGAIWRDCKILVKTSGSEQEVKRDRVSIKDNQKNRTFT 92

Query: 310 VVITGLRKEDAGRYLCGAHSDG 331
           V +  L K DA  Y CG    G
Sbjct: 93  VTMEDLMKTDADTYWCGIEKTG 114



 Score = 39.7 bits (91), Expect = 0.011
 Identities = 25/103 (24%), Positives = 48/103 (46%), Gaps = 11/103 (10%)

Query: 467 PGNVTAVLGETLKVPCHFPCKFSSYEKYWCK---WNNTGCQAL-----PSQDEGPSKAFV 518
           P  V  +   +L V C +   + +Y K+WC+   W +  C+ L       Q+    +  +
Sbjct: 25  PTTVNGLERGSLTVQCVYRSGWETYLKWWCRGAIWRD--CKILVKTSGSEQEVKRDRVSI 82

Query: 519 NCDENSRLVSLTLNLVTRADEGWYWCGV-KQGHFYGETAAVYV 560
             ++ +R  ++T+  + + D   YWCG+ K G+  G T  V +
Sbjct: 83  KDNQKNRTFTVTMEDLMKTDADTYWCGIEKTGNDLGVTVQVTI 125


>gi|239756941 PREDICTED: similar to CD300C antigen [Homo sapiens]
          Length = 328

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 40/135 (29%), Positives = 59/135 (43%), Gaps = 14/135 (10%)

Query: 13  FPAISTKSPIFGPEEVNSVEGNSVSITCYYPPTSVNRHTRKYWCRQGARGGCITLISSEG 72
           FP   T S   GP  V    G S+S+ C Y      +   KYWCRQ        ++ + G
Sbjct: 146 FPGCLTVS---GPSTVMGAVGESLSVQCRYEEKY--KTFNKYWCRQPCLPIWHEMVETGG 200

Query: 73  YVSSKYAGRANLTNFPENGTFVVNIAQLSQDDSGRYKCGLG--INSRGLS-------FDV 123
                 + +  +T+ P + TF V +  L+ DD+G+Y+CG+   +   GLS       F V
Sbjct: 201 SEGVVRSDQVIITDHPGDLTFTVTLENLTADDAGKYRCGIATILQEDGLSGFLPDPFFQV 260

Query: 124 SLEVSQGPGLLNDTK 138
            + VS      N  K
Sbjct: 261 QVLVSSASSTENSVK 275



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 34/93 (36%), Positives = 47/93 (50%), Gaps = 16/93 (17%)

Query: 356 PTVVKGVAGGSVAVLCPYNRKESKSIKYWC------LW-EGAQNGRCPLLVDSEGWVKAQ 408
           P+ V G  G S++V C Y  K     KYWC      +W E  + G       SEG V++ 
Sbjct: 155 PSTVMGAVGESLSVQCRYEEKYKTFNKYWCRQPCLPIWHEMVETG------GSEGVVRSD 208

Query: 409 YEGRLSLLEEPGNGTFTVILNQLTSRDAGFYWC 441
              ++ + + PG+ TFTV L  LT+ DAG Y C
Sbjct: 209 ---QVIITDHPGDLTFTVTLENLTADDAGKYRC 238



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 27/91 (29%), Positives = 40/91 (43%), Gaps = 16/91 (17%)

Query: 467 PGNVTAVLGETLKVPCHFPCKFSSYEKYWCKWNNTGCQALPSQDE----GPSKAFVNCDE 522
           P  V   +GE+L V C +  K+ ++ KYWC+        LP   E    G S+  V  D+
Sbjct: 155 PSTVMGAVGESLSVQCRYEEKYKTFNKYWCRQ-----PCLPIWHEMVETGGSEGVVRSDQ 209

Query: 523 -------NSRLVSLTLNLVTRADEGWYWCGV 546
                       ++TL  +T  D G Y CG+
Sbjct: 210 VIITDHPGDLTFTVTLENLTADDAGKYRCGI 240



 Score = 37.0 bits (84), Expect = 0.069
 Identities = 21/85 (24%), Positives = 36/85 (42%)

Query: 242 PELVYEDLRGSVTFHCALGPEVANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLNP 301
           P  V   +  S++  C    +     K+ CRQ        +V T G        ++++  
Sbjct: 155 PSTVMGAVGESLSVQCRYEEKYKTFNKYWCRQPCLPIWHEMVETGGSEGVVRSDQVIITD 214

Query: 302 QDKDGSFSVVITGLRKEDAGRYLCG 326
              D +F+V +  L  +DAG+Y CG
Sbjct: 215 HPGDLTFTVTLENLTADDAGKYRCG 239


>gi|239751445 PREDICTED: similar to CD300C antigen [Homo sapiens]
          Length = 259

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 40/135 (29%), Positives = 59/135 (43%), Gaps = 14/135 (10%)

Query: 13  FPAISTKSPIFGPEEVNSVEGNSVSITCYYPPTSVNRHTRKYWCRQGARGGCITLISSEG 72
           FP   T S   GP  V    G S+S+ C Y      +   KYWCRQ        ++ + G
Sbjct: 77  FPGCLTVS---GPSTVMGAVGESLSVQCRYEEKY--KTFNKYWCRQPCLPIWHEMVETGG 131

Query: 73  YVSSKYAGRANLTNFPENGTFVVNIAQLSQDDSGRYKCGLG--INSRGLS-------FDV 123
                 + +  +T+ P + TF V +  L+ DD+G+Y+CG+   +   GLS       F V
Sbjct: 132 SEGVVRSDQVIITDHPGDLTFTVTLENLTADDAGKYRCGIATILQEDGLSGFLPDPFFQV 191

Query: 124 SLEVSQGPGLLNDTK 138
            + VS      N  K
Sbjct: 192 QVLVSSASSTENSVK 206



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 34/93 (36%), Positives = 47/93 (50%), Gaps = 16/93 (17%)

Query: 356 PTVVKGVAGGSVAVLCPYNRKESKSIKYWC------LW-EGAQNGRCPLLVDSEGWVKAQ 408
           P+ V G  G S++V C Y  K     KYWC      +W E  + G       SEG V++ 
Sbjct: 86  PSTVMGAVGESLSVQCRYEEKYKTFNKYWCRQPCLPIWHEMVETG------GSEGVVRSD 139

Query: 409 YEGRLSLLEEPGNGTFTVILNQLTSRDAGFYWC 441
              ++ + + PG+ TFTV L  LT+ DAG Y C
Sbjct: 140 ---QVIITDHPGDLTFTVTLENLTADDAGKYRC 169



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 27/91 (29%), Positives = 40/91 (43%), Gaps = 16/91 (17%)

Query: 467 PGNVTAVLGETLKVPCHFPCKFSSYEKYWCKWNNTGCQALPSQDE----GPSKAFVNCDE 522
           P  V   +GE+L V C +  K+ ++ KYWC+        LP   E    G S+  V  D+
Sbjct: 86  PSTVMGAVGESLSVQCRYEEKYKTFNKYWCRQ-----PCLPIWHEMVETGGSEGVVRSDQ 140

Query: 523 -------NSRLVSLTLNLVTRADEGWYWCGV 546
                       ++TL  +T  D G Y CG+
Sbjct: 141 VIITDHPGDLTFTVTLENLTADDAGKYRCGI 171



 Score = 37.0 bits (84), Expect = 0.069
 Identities = 21/85 (24%), Positives = 36/85 (42%)

Query: 242 PELVYEDLRGSVTFHCALGPEVANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLNP 301
           P  V   +  S++  C    +     K+ CRQ        +V T G        ++++  
Sbjct: 86  PSTVMGAVGESLSVQCRYEEKYKTFNKYWCRQPCLPIWHEMVETGGSEGVVRSDQVIITD 145

Query: 302 QDKDGSFSVVITGLRKEDAGRYLCG 326
              D +F+V +  L  +DAG+Y CG
Sbjct: 146 HPGDLTFTVTLENLTADDAGKYRCG 170


>gi|239745950 PREDICTED: similar to CD300C antigen [Homo sapiens]
          Length = 328

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 40/135 (29%), Positives = 59/135 (43%), Gaps = 14/135 (10%)

Query: 13  FPAISTKSPIFGPEEVNSVEGNSVSITCYYPPTSVNRHTRKYWCRQGARGGCITLISSEG 72
           FP   T S   GP  V    G S+S+ C Y      +   KYWCRQ        ++ + G
Sbjct: 146 FPGCLTVS---GPSTVMGAVGESLSVQCRYEEKY--KTFNKYWCRQPCLPIWHEMVETGG 200

Query: 73  YVSSKYAGRANLTNFPENGTFVVNIAQLSQDDSGRYKCGLG--INSRGLS-------FDV 123
                 + +  +T+ P + TF V +  L+ DD+G+Y+CG+   +   GLS       F V
Sbjct: 201 SEGVVRSDQVIITDHPGDLTFTVTLENLTADDAGKYRCGIATILQEDGLSGFLPDPFFQV 260

Query: 124 SLEVSQGPGLLNDTK 138
            + VS      N  K
Sbjct: 261 QVLVSSASSTENSVK 275



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 34/93 (36%), Positives = 47/93 (50%), Gaps = 16/93 (17%)

Query: 356 PTVVKGVAGGSVAVLCPYNRKESKSIKYWC------LW-EGAQNGRCPLLVDSEGWVKAQ 408
           P+ V G  G S++V C Y  K     KYWC      +W E  + G       SEG V++ 
Sbjct: 155 PSTVMGAVGESLSVQCRYEEKYKTFNKYWCRQPCLPIWHEMVETG------GSEGVVRSD 208

Query: 409 YEGRLSLLEEPGNGTFTVILNQLTSRDAGFYWC 441
              ++ + + PG+ TFTV L  LT+ DAG Y C
Sbjct: 209 ---QVIITDHPGDLTFTVTLENLTADDAGKYRC 238



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 27/91 (29%), Positives = 40/91 (43%), Gaps = 16/91 (17%)

Query: 467 PGNVTAVLGETLKVPCHFPCKFSSYEKYWCKWNNTGCQALPSQDE----GPSKAFVNCDE 522
           P  V   +GE+L V C +  K+ ++ KYWC+        LP   E    G S+  V  D+
Sbjct: 155 PSTVMGAVGESLSVQCRYEEKYKTFNKYWCRQ-----PCLPIWHEMVETGGSEGVVRSDQ 209

Query: 523 -------NSRLVSLTLNLVTRADEGWYWCGV 546
                       ++TL  +T  D G Y CG+
Sbjct: 210 VIITDHPGDLTFTVTLENLTADDAGKYRCGI 240



 Score = 37.0 bits (84), Expect = 0.069
 Identities = 21/85 (24%), Positives = 36/85 (42%)

Query: 242 PELVYEDLRGSVTFHCALGPEVANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLNP 301
           P  V   +  S++  C    +     K+ CRQ        +V T G        ++++  
Sbjct: 155 PSTVMGAVGESLSVQCRYEEKYKTFNKYWCRQPCLPIWHEMVETGGSEGVVRSDQVIITD 214

Query: 302 QDKDGSFSVVITGLRKEDAGRYLCG 326
              D +F+V +  L  +DAG+Y CG
Sbjct: 215 HPGDLTFTVTLENLTADDAGKYRCG 239


>gi|169646348 CD300 molecule-like family member d [Homo sapiens]
          Length = 194

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 43/157 (27%), Positives = 63/157 (40%), Gaps = 11/157 (7%)

Query: 9   LLAVFPAISTKSPIFGPEEVNSVEGNSVSITCYYPPTSVNRHTRKYWCRQGARGG-CITL 67
           LL + P  S  + I GP  VN  E  S+++ C Y        T   W  QGA    C  L
Sbjct: 8   LLLILPGYSIAAKITGPTTVNGSEQGSLTVQCAY---GSGWETYLKWRCQGADWNYCNIL 64

Query: 68  ISSEGYVSSKYAGRANLTNFPENGTFVVNIAQLSQDDSGRYKCGLGINSRGLSFDVSLEV 127
           + + G        R ++ +  +N  F V +  L +DD+  Y C  G    G+   V ++V
Sbjct: 65  VKTNGSEQEVKKNRVSIRDNQKNHVFTVTMENLKRDDADSYWC--GTERPGIDLGVKVQV 122

Query: 128 SQGPGLLNDTKVYTVDLGRTVTINCPFKTENAQKRKS 164
           +  PG       +T     T T +  F     QK  S
Sbjct: 123 TINPGTQTAVSEWT-----TTTASLAFTAAATQKTSS 154



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 30/88 (34%), Positives = 42/88 (47%), Gaps = 2/88 (2%)

Query: 356 PTVVKGVAGGSVAVLCPYNRKESKSIKYWCLWEGAQNGRCPLLVDSEGWVKAQYEGRLSL 415
           PT V G   GS+ V C Y       +K+ C  +GA    C +LV + G  +   + R+S+
Sbjct: 24  PTTVNGSEQGSLTVQCAYGSGWETYLKWRC--QGADWNYCNILVKTNGSEQEVKKNRVSI 81

Query: 416 LEEPGNGTFTVILNQLTSRDAGFYWCLT 443
            +   N  FTV +  L   DA  YWC T
Sbjct: 82  RDNQKNHVFTVTMENLKRDDADSYWCGT 109



 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 25/90 (27%), Positives = 42/90 (46%)

Query: 242 PELVYEDLRGSVTFHCALGPEVANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLNP 301
           P  V    +GS+T  CA G       K+ C+ +    C+++V T G      + R+ +  
Sbjct: 24  PTTVNGSEQGSLTVQCAYGSGWETYLKWRCQGADWNYCNILVKTNGSEQEVKKNRVSIRD 83

Query: 302 QDKDGSFSVVITGLRKEDAGRYLCGAHSDG 331
             K+  F+V +  L+++DA  Y CG    G
Sbjct: 84  NQKNHVFTVTMENLKRDDADSYWCGTERPG 113



 Score = 30.8 bits (68), Expect = 4.9
 Identities = 22/94 (23%), Positives = 43/94 (45%), Gaps = 12/94 (12%)

Query: 465 KVPGNVTAVLGE--TLKVPCHFPCKFSSYEKYWCK---WNNTGCQAL-----PSQDEGPS 514
           K+ G  T    E  +L V C +   + +Y K+ C+   WN   C  L       Q+   +
Sbjct: 20  KITGPTTVNGSEQGSLTVQCAYGSGWETYLKWRCQGADWNY--CNILVKTNGSEQEVKKN 77

Query: 515 KAFVNCDENSRLVSLTLNLVTRADEGWYWCGVKQ 548
           +  +  ++ + + ++T+  + R D   YWCG ++
Sbjct: 78  RVSIRDNQKNHVFTVTMENLKRDDADSYWCGTER 111


>gi|38490688 immunoglobulin superfamily, member 10 [Homo sapiens]
          Length = 2623

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 75/290 (25%), Positives = 122/290 (42%), Gaps = 43/290 (14%)

Query: 204  SVVINQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKPEPELVYEDLRGSVTFHCALGPEV 263
            S+ IN+++L D+G+Y+C A + S  + K   L V+   P      + G  T    +    
Sbjct: 2197 SLTINKVKLLDSGEYVCVARNPSGDDTKMYKLDVVSKPPL-----INGLYTNRTVIKATA 2251

Query: 264  ANVAK--FLCRQS---SGENCDVVVNTLGKRAPAFEGRILLNPQDKDGSFSVVITGLRKE 318
               +K  F CR     S E   ++ + +   AP +  RI ++   K+G+    I  +R  
Sbjct: 2252 VRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVH---KNGTLE--IRNVRLS 2306

Query: 319  DAGRYLCGAHSDGQLQEGSPIQAWQLFVNEESTIP--RSPTVVKGVA--GGSVAVLCPYN 374
            D+  ++C A ++G    G  +   QL V E    P  R+P   K VA  G S A+ C  +
Sbjct: 2307 DSADFICVARNEG----GESVLVVQLEVLEMLRRPTFRNPFNEKIVAQLGKSTALNCSVD 2362

Query: 375  RKESKSIKYWCLWEGAQNGRCPLLVDSEGWVKAQYEGRLSLLEEPGNGTFTVILNQLTSR 434
                  I  W L  G +    P            Y+  ++      NG+F  I+++ T  
Sbjct: 2363 GNPPPEI-IWILPNGTRFSNGP----------QSYQYLIA-----SNGSF--IISKTTRE 2404

Query: 435  DAGFYWCLTNGDTLWRTTVEIKIIEGEPNL--KVPGNVTAVLGETLKVPC 482
            DAG Y C       +   + I  I  +P +    PG V  + GE+L + C
Sbjct: 2405 DAGKYRCAARNKVGYIEKLVILEIGQKPVILTYAPGTVKGISGESLSLHC 2454



 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 95/415 (22%), Positives = 167/415 (40%), Gaps = 75/415 (18%)

Query: 87   FPENGTFVVNIAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGPGLLNDTKVYTVDLGR 146
            F  NG+  +N  +L   DSG Y C     S   +    L+V   P L+N        +  
Sbjct: 2192 FHANGSLTINKVKLL--DSGEYVCVARNPSGDDTKMYKLDVVSKPPLINGLYTNRTVIKA 2249

Query: 147  TVTINCPFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQGTGQLLFSVV 206
            T   +     +   +     + + + P    D+     P Y  RI +   GT      + 
Sbjct: 2250 TAVRHSKKHFDCRAEGTPSPEVMWIMP----DNIFLTAPYYGSRITVHKNGT------LE 2299

Query: 207  INQLRLSDAGQYLCQAGDDSNSNKKNADLQVLK---------PEPELVYEDLRGSVTFHC 257
            I  +RLSD+  ++C A ++   +     L+VL+         P  E +   L  S   +C
Sbjct: 2300 IRNVRLSDSADFICVARNEGGESVLVVQLEVLEMLRRPTFRNPFNEKIVAQLGKSTALNC 2359

Query: 258  ALG----PEVANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLNPQDKDGSFSVVIT 313
            ++     PE+  +     R S+G               +++  I  N     GSF  +I+
Sbjct: 2360 SVDGNPPPEIIWILPNGTRFSNGPQ-------------SYQYLIASN-----GSF--IIS 2399

Query: 314  GLRKEDAGRYLCGAHSD-GQLQEGSPIQAWQLFVNEESTIPRSPTVVKGVAGGSVAVLCP 372
               +EDAG+Y C A +  G +++   ++  Q  V     +  +P  VKG++G S+++ C 
Sbjct: 2400 KTTREDAGKYRCAARNKVGYIEKLVILEIGQKPV----ILTYAPGTVKGISGESLSLHCV 2455

Query: 373  YNRKESKSIKYWCLWEGAQNGRCPLLVDSEGWVKAQYEGRLSLLEEPGNGTFTVILNQLT 432
             +     +IK W +  G        +VD     + Q  G+  L +   NG  T+++ + T
Sbjct: 2456 SDGIPKPNIK-WTMPSG-------YVVD-----RPQINGKYILHD---NG--TLVIKEAT 2497

Query: 433  SRDAGFYWCLTN---GDTLWRTTVEIKIIEGEPNL--KVPGNVTAVLGETLKVPC 482
            + D G Y C      G TL   TV + I+   P +  + P ++    G   ++ C
Sbjct: 2498 AYDRGNYICKAQNSVGHTL--ITVPVMIVAYPPRITNRPPRSIVTRTGAAFQLHC 2550



 Score = 36.6 bits (83), Expect = 0.090
 Identities = 53/242 (21%), Positives = 87/242 (35%), Gaps = 29/242 (11%)

Query: 207  INQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKPEPELVYEDLRGSVTFHCALGPEVANV 266
            I ++ + D GQYLC A +   ++  +  L V+   P ++ E     +T H        + 
Sbjct: 1710 IQRVEIQDRGQYLCSASNLFGTDHLHVTLSVVSYPPRIL-ERRTKEITVHS------GST 1762

Query: 267  AKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLNPQDKDGSFSVVITGLRKEDAGRYLCG 326
             +  CR + G     V   L  +    E              ++V+  L   D G Y C 
Sbjct: 1763 VELKCR-AEGRPSPTVTWILANQTVVSESSQGSRQAVVTVDGTLVLHNLSIYDRGFYKCV 1821

Query: 327  AHSDGQLQEGSPIQAWQLFVNEESTIPRSPTVVKGVAGGSVAVLCPYNRKESKSIKYWCL 386
            A + G   + S +   Q+       + +   V+ G  G S+ + C        S+ YW L
Sbjct: 1822 ASNPG--GQDSLLVKIQVIAAPPVILEQRRQVIVGTWGESLKLPCTAKGTPQPSV-YWVL 1878

Query: 387  WEGAQNGRCPLLVDSEGWVK-AQYEGRLSLLEEPGNGTFTVILNQLTSRDAGFYWCLTNG 445
             +G +             VK  Q+      L   G    T+ +  L S D G Y C+   
Sbjct: 1879 SDGTE-------------VKPLQFTNSKLFLFSNG----TLYIRNLASSDRGTYECIATS 1921

Query: 446  DT 447
             T
Sbjct: 1922 ST 1923



 Score = 36.2 bits (82), Expect = 0.12
 Identities = 44/188 (23%), Positives = 77/188 (40%), Gaps = 34/188 (18%)

Query: 90   NGTFVVNIAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGPGLLNDTKVYTVDL-GRTV 148
            NG+F+  I++ +++D+G+Y+C        +   V LE+ Q P +L         + G ++
Sbjct: 2393 NGSFI--ISKTTREDAGKYRCAARNKVGYIEKLVILEIGQKPVILTYAPGTVKGISGESL 2450

Query: 149  TINCPFKTENAQKRKSLYKQIGLYPVLVIDSSGYV--NPNYTGRIRLDIQGTGQLLFSVV 206
            +++C   ++   K    +             SGYV   P   G+  L   GT      +V
Sbjct: 2451 SLHCV--SDGIPKPNIKWTM----------PSGYVVDRPQINGKYILHDNGT------LV 2492

Query: 207  INQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKPEPELVYEDLRGSVT-------FHC-A 258
            I +    D G Y+C+A +          + ++   P +     R  VT        HC A
Sbjct: 2493 IKEATAYDRGNYICKAQNSVGHTLITVPVMIVAYPPRITNRPPRSIVTRTGAAFQLHCVA 2552

Query: 259  LG---PEV 263
            LG   PE+
Sbjct: 2553 LGVPKPEI 2560



 Score = 34.7 bits (78), Expect = 0.34
 Identities = 41/164 (25%), Positives = 69/164 (42%), Gaps = 30/164 (18%)

Query: 329 SDGQLQ----EGSPIQAWQLFVNEESTIPRSPTVVKGVAGGSVAVLCPYNRKESKSIKYW 384
           SD Q+     E  P++     ++ ++      TV+    GG+V + CP     +  +  W
Sbjct: 454 SDAQITLPRAEMRPVKHKWTMISRDNNTKLEHTVL---VGGTVGLNCPGQGDPTPHVD-W 509

Query: 385 CLWEGAQNGRCPLLVDSEGWVKAQYEGRLSLLEEPGNGTFTVILNQLTSRDAGFYWCLTN 444
            L +G++  R P  V  +G +     G+L L                 S D G Y C+++
Sbjct: 510 LLADGSKV-RAPY-VSEDGRILIDKSGKLEL-------------QMADSFDTGVYHCISS 554

Query: 445 G----DTL-WRTTVEIKIIEGEPNLKVPGNVTAVLGETLKVPCH 483
                D L +R TV   ++E      +  + T  +GETL +PCH
Sbjct: 555 NYDDADILTYRITVVEPLVEAYQENGI--HHTVFIGETLDLPCH 596



 Score = 30.0 bits (66), Expect = 8.4
 Identities = 40/162 (24%), Positives = 63/162 (38%), Gaps = 27/162 (16%)

Query: 90   NGTFVVNIAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGPGLLND--TKVYTVDLGRT 147
            NGT  ++I ++   D G+Y C            V+L V   P  + +  TK  TV  G T
Sbjct: 1705 NGT--LSIQRVEIQDRGQYLCSASNLFGTDHLHVTLSVVSYPPRILERRTKEITVHSGST 1762

Query: 148  VTINCPFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQGTGQLLFSV-- 205
            V + C      A+ R S      L    V+  S               QG+ Q + +V  
Sbjct: 1763 VELKC-----RAEGRPSPTVTWILANQTVVSESS--------------QGSRQAVVTVDG 1803

Query: 206  --VINQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKPEPELV 245
              V++ L + D G Y C A +    +     +QV+   P ++
Sbjct: 1804 TLVLHNLSIYDRGFYKCVASNPGGQDSLLVKIQVIAAPPVIL 1845


>gi|9507203 triggering receptor expressed on myeloid cells 2
           precursor [Homo sapiens]
          Length = 230

 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 41/121 (33%), Positives = 60/121 (49%), Gaps = 11/121 (9%)

Query: 344 LFVNEESTIPRSPTVVKGVAGGSVAVLCPY-NRKESKSIKYWCLWEGAQNGRCPLLVDSE 402
           LFV E S    + TV +GVAG S+ V CPY + K     K WC   G + G C  +V + 
Sbjct: 10  LFVTELSGA-HNTTVFQGVAGQSLQVSCPYDSMKHWGRRKAWCRQLG-EKGPCQRVVSTH 67

Query: 403 G-WVKA---QYEGRLSLLEEPGNGTFTVILNQLTSRDAGFYWCL----TNGDTLWRTTVE 454
             W+ +   ++ G  ++ ++   GT T+ L  L   DAG Y C     +  DTL +  VE
Sbjct: 68  NLWLLSFLRRWNGSTAITDDTLGGTLTITLRNLQPHDAGLYQCQSLHGSEADTLRKVLVE 127

Query: 455 I 455
           +
Sbjct: 128 V 128



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 6/85 (7%)

Query: 31  VEGNSVSITCYYPPTSVNRHTRKYWCRQ-GARGGCITLISSEGYVSSKYAGRAN----LT 85
           V G S+ ++C Y     +   RK WCRQ G +G C  ++S+       +  R N    +T
Sbjct: 27  VAGQSLQVSCPYDSMK-HWGRRKAWCRQLGEKGPCQRVVSTHNLWLLSFLRRWNGSTAIT 85

Query: 86  NFPENGTFVVNIAQLSQDDSGRYKC 110
           +    GT  + +  L   D+G Y+C
Sbjct: 86  DDTLGGTLTITLRNLQPHDAGLYQC 110


>gi|154759271 CD300 molecule-like family member b [Homo sapiens]
          Length = 238

 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 27/88 (30%), Positives = 44/88 (50%), Gaps = 2/88 (2%)

Query: 354 RSPTVVKGVAGGSVAVLCPYNRKESKSIKYWCLWEGAQNGRCPLLVDSEGWVKAQYEGRL 413
           + P  V+    GS+ V C Y +     IK+WC   G +   C +L+++ G  + +   R+
Sbjct: 56  QGPESVRAPEQGSLTVQCHYKQGWETYIKWWC--RGVRWDTCKILIETRGSEQGEKSDRV 113

Query: 414 SLLEEPGNGTFTVILNQLTSRDAGFYWC 441
           S+ +   + TFTV +  L   DA  YWC
Sbjct: 114 SIKDNQKDRTFTVTMEGLRRDDADVYWC 141



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 27/90 (30%), Positives = 41/90 (45%)

Query: 242 PELVYEDLRGSVTFHCALGPEVANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLNP 301
           PE V    +GS+T  C          K+ CR    + C +++ T G        R+ +  
Sbjct: 58  PESVRAPEQGSLTVQCHYKQGWETYIKWWCRGVRWDTCKILIETRGSEQGEKSDRVSIKD 117

Query: 302 QDKDGSFSVVITGLRKEDAGRYLCGAHSDG 331
             KD +F+V + GLR++DA  Y CG    G
Sbjct: 118 NQKDRTFTVTMEGLRRDDADVYWCGIERRG 147



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 33/113 (29%), Positives = 53/113 (46%), Gaps = 10/113 (8%)

Query: 22  IFGPEEVNSVEGNSVSITCYYPP---TSVNRHTRKYWCRQGARGGCITLISSEGYVSSKY 78
           I GPE V + E  S+++ C+Y     T +     K+WCR      C  LI + G    + 
Sbjct: 55  IQGPESVRAPEQGSLTVQCHYKQGWETYI-----KWWCRGVRWDTCKILIETRGSEQGEK 109

Query: 79  AGRANLTNFPENGTFVVNIAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGP 131
           + R ++ +  ++ TF V +  L +DD+  Y C  GI  RG      ++V   P
Sbjct: 110 SDRVSIKDNQKDRTFTVTMEGLRRDDADVYWC--GIERRGPDLGTQVKVIVDP 160



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 24/94 (25%), Positives = 47/94 (50%), Gaps = 10/94 (10%)

Query: 463 NLKVPGNVTAVLGETLKVPCHFPCKFSSYEKYWC---KWNNTGCQAL-----PSQDEGPS 514
           +++ P +V A    +L V CH+   + +Y K+WC   +W+   C+ L       Q E   
Sbjct: 54  SIQGPESVRAPEQGSLTVQCHYKQGWETYIKWWCRGVRWDT--CKILIETRGSEQGEKSD 111

Query: 515 KAFVNCDENSRLVSLTLNLVTRADEGWYWCGVKQ 548
           +  +  ++  R  ++T+  + R D   YWCG+++
Sbjct: 112 RVSIKDNQKDRTFTVTMEGLRRDDADVYWCGIER 145


>gi|37700254 triggering receptor expressed on myeloid cells-like 4
           [Homo sapiens]
          Length = 200

 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 32/110 (29%), Positives = 54/110 (49%), Gaps = 4/110 (3%)

Query: 25  PEEVNSVEGNSVSITCYYPPTSVNRHTRKYWCRQGARGGCITLISSEGYVSSKYAGRANL 84
           PEE++   G ++ + C Y P     +  K WC+Q +   C  L++S    ++       +
Sbjct: 25  PEELHKHPGQTLLLQCQYSPKR-GPYQPKSWCQQTSPSRCTLLVTSSKPWTAVQKSHYTI 83

Query: 85  TNFPENGTFVVNIAQLSQDDSGRYKCGLGINSRGLSF---DVSLEVSQGP 131
            + P  G F + + QL+Q+DSG Y CG+   S  +     ++SL VS  P
Sbjct: 84  WDKPNAGFFNITMIQLTQNDSGFYWCGIYNASENIITVLRNISLVVSPAP 133



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 26/79 (32%), Positives = 39/79 (49%), Gaps = 3/79 (3%)

Query: 364 GGSVAVLCPYNRKESK-SIKYWCLWEGAQNGRCPLLVDSEGWVKAQYEGRLSLLEEPGNG 422
           G ++ + C Y+ K      K WC  +     RC LLV S     A  +   ++ ++P  G
Sbjct: 33  GQTLLLQCQYSPKRGPYQPKSWC--QQTSPSRCTLLVTSSKPWTAVQKSHYTIWDKPNAG 90

Query: 423 TFTVILNQLTSRDAGFYWC 441
            F + + QLT  D+GFYWC
Sbjct: 91  FFNITMIQLTQNDSGFYWC 109



 Score = 36.6 bits (83), Expect = 0.090
 Identities = 24/92 (26%), Positives = 39/92 (42%), Gaps = 7/92 (7%)

Query: 462 PNLKVPGNVTAVLGETLKVPCHFPCKFSSYE-KYWCKWNNTGCQALPSQDEGPSKAFVNC 520
           P   VP  +    G+TL + C +  K   Y+ K WC+  +     L      P  A    
Sbjct: 20  PQGAVPEELHKHPGQTLLLQCQYSPKRGPYQPKSWCQQTSPSRCTLLVTSSKPWTAVQKS 79

Query: 521 D------ENSRLVSLTLNLVTRADEGWYWCGV 546
                   N+   ++T+  +T+ D G+YWCG+
Sbjct: 80  HYTIWDKPNAGFFNITMIQLTQNDSGFYWCGI 111



 Score = 30.0 bits (66), Expect = 8.4
 Identities = 18/89 (20%), Positives = 39/89 (43%), Gaps = 1/89 (1%)

Query: 242 PELVYEDLRGSVTFHCALGPEVANVA-KFLCRQSSGENCDVVVNTLGKRAPAFEGRILLN 300
           PE +++    ++   C   P+      K  C+Q+S   C ++V +        +    + 
Sbjct: 25  PEELHKHPGQTLLLQCQYSPKRGPYQPKSWCQQTSPSRCTLLVTSSKPWTAVQKSHYTIW 84

Query: 301 PQDKDGSFSVVITGLRKEDAGRYLCGAHS 329
            +   G F++ +  L + D+G Y CG ++
Sbjct: 85  DKPNAGFFNITMIQLTQNDSGFYWCGIYN 113


>gi|58331253 obscurin, cytoskeletal calmodulin and titin-interacting
            RhoGEF isoform a [Homo sapiens]
          Length = 6620

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 102/456 (22%), Positives = 165/456 (36%), Gaps = 94/456 (20%)

Query: 95   VNIAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGPGLLNDTKVYTVDLGRTVTINCPF 154
            + I  LS  D+G Y C  G      +  V    +  P      +    + G T T+ C  
Sbjct: 3857 LQIHGLSVADTGEYSCVCGQERTSATLTVR---APQPVFREPLQSLQAEEGSTATLQCEL 3913

Query: 155  KTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQG-TGQLLFSVVINQLRLS 213
                A                V+ S G +     GR    +QG T +L    V+  L+  
Sbjct: 3914 SEPTAT---------------VVWSKGGLQLQANGRREPRLQGCTAEL----VLQDLQRE 3954

Query: 214  DAGQYLCQAGDDSNSNKKNADLQVLKPEPELVYEDLRGSVTFHCALGPEVANVAKFLCRQ 273
            D G+Y C  G  + S         ++   EL ++++    T H             LC +
Sbjct: 3955 DTGEYTCTCGSQATSATLTVTAAPVRFLRELQHQEVDEGGTAH-------------LCCE 4001

Query: 274  SSGENCDVVVNTLGKRAPAFEGRILLNPQDK-----DGSFS-VVITGLRKEDAGRYLCGA 327
             S     V            +G + L P  K     DG+ + +++ G+ +EDAG Y C  
Sbjct: 4002 LSRAGASVEWR---------KGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTCDT 4052

Query: 328  HSDGQLQEGSPIQAWQLFVNEESTIPRSPTVVKGV---AGGSVAVLCPYNRKESKSIKYW 384
               G  Q  + +             P+  T ++ +    G    + C  +  ES ++  W
Sbjct: 4053 ---GHTQSMASLSV-------RVPRPKFKTRLQSLEQETGDIARLCCQLSDAESGAVVQW 4102

Query: 385  CLWEGAQNGRCPLLVDSEGWVKAQYEGRLSLLEEPGNGTFTVILNQLTSRDAGFYWCLTN 444
             L EG +    P           +YE R          T  ++++QL ++D G Y C+T 
Sbjct: 4103 -LKEGVELHAGP-----------KYEMRSQ------GATRELLIHQLEAKDTGEYACVTG 4144

Query: 445  GDTLWRTTVEIKIIEGEPNLKVPGNVTAVLGETLKVPCHFPCKFSSYEKYWCKWNNTGCQ 504
            G    +T   +++ E E  + V G V A +  T      F C+ S       +W     Q
Sbjct: 4145 GQ---KTAASLRVTEPEVTI-VRGLVDAEV--TADEDVEFSCEVSRAGATGVQW---CLQ 4195

Query: 505  ALPSQDEGPSKAFVNCDENSRLVSLTLNLVTRADEG 540
             LP Q    ++  V    + R+ +L L  VT  D G
Sbjct: 4196 GLPLQSNEVTEVAV---RDGRIHTLRLKGVTPEDAG 4228



 Score = 39.7 bits (91), Expect = 0.011
 Identities = 97/463 (20%), Positives = 163/463 (35%), Gaps = 89/463 (19%)

Query: 28   VNSVEGNSVSITCYYPPTSVNRHTRKYWCRQGARGGCITLISSEGYVSSKYAGRANLTNF 87
            V++V G      C     +   H   +W + G   G     S E ++      R  L   
Sbjct: 807  VDAVAGGPAQFEC----ETSEAHVHVHWYKDGMELGH----SGERFLQEDVGTRHRLV-- 856

Query: 88   PENGTFVVNIAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGPGLLNDTKV----YTVD 143
                      A +++ D G Y C +G +S     D  L VS+   +    ++       +
Sbjct: 857  ---------AATVTRQDEGTYSCRVGEDS----VDFRLRVSEPKVVFAKEQLARRKLQAE 903

Query: 144  LGRTVTINCPFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQGTGQLLF 203
             G + T++C  +   AQ   + YK         + SS  V    TG  R           
Sbjct: 904  AGASATLSC--EVAQAQTEVTWYKD-----GKKLSSSSKVCMEATGCTR----------- 945

Query: 204  SVVINQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKPEPELVYEDLRGSVTFHCALGPEV 263
             +V+ Q   +DAG+Y C+AG      + +  L V   EP++V+         H  +  E 
Sbjct: 946  RLVVQQAGQADAGEYSCEAG----GQRLSFHLDV--KEPKVVFAK---DQVAHSEVQAEA 996

Query: 264  ANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLNPQDKDGSFSVVITGLRKEDAGRY 323
               A   C  +  +  +V+    GK+       + ++ + K     +V+    K DAG Y
Sbjct: 997  GASATLSCEVAQAQT-EVMWYKDGKK---LSSSLKVHVEAKGCRRRLVVQQAGKTDAGDY 1052

Query: 324  LCGAHSDGQLQEGSPIQAWQLFVNEESTIPRSPTVVKGVAGGSVAVLCPYNRKESKSIKY 383
             C A            +   +F  E+S        V+  AG S  + C   + +++   Y
Sbjct: 1053 SCEARGQRVSFRLHITEPKMMFAKEQSV----HNEVQAEAGASAMLSCEVAQAQTEVTWY 1108

Query: 384  WCLWEGAQNGRCPLLVDSEGWVKAQYEGRLSLLEEPGNGTFTVILNQLTSRDAGFYWCLT 443
                   ++G+    + S   V  + +G           T  ++L Q    DAG Y C  
Sbjct: 1109 -------KDGK---KLSSSSKVGMEVKG----------CTRRLVLPQAGKADAGEYSCEA 1148

Query: 444  NGDTLWRTTVEIKIIEGE----PNLKVPGNVTAVLGETLKVPC 482
             G    R +  + I E +        V   V A  G T  + C
Sbjct: 1149 GGQ---RVSFHLHITEPKGVFAKEQSVHNEVQAEAGTTAMLSC 1188



 Score = 36.6 bits (83), Expect = 0.090
 Identities = 45/181 (24%), Positives = 71/181 (39%), Gaps = 26/181 (14%)

Query: 92   TFVVNIAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGPGLLNDTKVYTVDLGRTVTIN 151
            T  V+ AQ+   DS  Y C +G   +     V    ++   LL        +LG TVT+ 
Sbjct: 1775 TLTVHGAQVL--DSAIYSCRVGAEGQDFPVQVEEVAAKFCRLLEPV---CGELGGTVTLA 1829

Query: 152  CPFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQGTGQLLFSVVINQLR 211
            C      A+               V+   G        R ++  +G  +   S+ +  LR
Sbjct: 1830 CELSPACAE---------------VVWRCGNTQLRVGKRFQMVAEGPVR---SLTVLGLR 1871

Query: 212  LSDAGQYLCQAGDDSNSNKKNADL-QVLKPEPEL--VYEDLRGSVTFHCALGPEVANVAK 268
              DAG+Y+C++ DD  S +    + +V+K    L  V  +  G  TF C + P    V  
Sbjct: 1872 AEDAGEYVCESRDDHTSAQLTVSVPRVVKFMSGLSTVVAEEGGEATFQCVVSPSDVAVVW 1931

Query: 269  F 269
            F
Sbjct: 1932 F 1932



 Score = 35.8 bits (81), Expect = 0.15
 Identities = 50/247 (20%), Positives = 94/247 (38%), Gaps = 55/247 (22%)

Query: 27   EVNSVEGNSVSITCYYPPTSVNRHTRKYWCRQGARGGCITLISSEGYVSSKYAGRANLTN 86
            EV +  G S  ++C          T   W + G +      +SS   V  +  G      
Sbjct: 1083 EVQAEAGASAMLSCEV----AQAQTEVTWYKDGKK------LSSSSKVGMEVKGCTRRLV 1132

Query: 87   FPENGTFVVNIAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGPGLL-NDTKVYT---V 142
             P+ G          + D+G Y C  G    G      L +++  G+   +  V+     
Sbjct: 1133 LPQAG----------KADAGEYSCEAG----GQRVSFHLHITEPKGVFAKEQSVHNEVQA 1178

Query: 143  DLGRTVTINCPFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQGTGQLL 202
            + G T  ++C  +    Q   + YK                  + + ++R++++G  + L
Sbjct: 1179 EAGTTAMLSC--EVAQPQTEVTWYKD-------------GKKLSSSSKVRMEVKGCTRRL 1223

Query: 203  FSVVINQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKP-----EPELVYEDLRGSVTFHC 257
               V+ Q+  +DAG+Y C+AG      + +  L + +P     + +LV+ ++R       
Sbjct: 1224 ---VVQQVGKADAGEYSCEAG----GQRVSFQLHITEPKAVFAKEQLVHNEVRTEAGASA 1276

Query: 258  ALGPEVA 264
             L  EVA
Sbjct: 1277 TLSCEVA 1283



 Score = 35.8 bits (81), Expect = 0.15
 Identities = 46/200 (23%), Positives = 74/200 (37%), Gaps = 30/200 (15%)

Query: 262  EVANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLNPQDKDGSFSVVITGLRKEDAG 321
            E+    K  CR +      +     GK        IL+  +D DGS ++++  L   D+G
Sbjct: 6026 ELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILI--EDPDGSCALILDSLTGVDSG 6083

Query: 322  RYLC-GAHSDGQLQEGSPI--QAWQLFVNEESTIPRSPTVVKGVAGGSVAVLCPYNRKES 378
            +Y+C  A + G       I  Q    FVN+   +  SP V                  E 
Sbjct: 6084 QYMCFAASAAGNCSTLGKILVQVPPRFVNK---VRASPFV------------------EG 6122

Query: 379  KSIKYWCLWEGAQNGRCPLLVDSEGWVKAQYEGRLSLLEEPGNGTFTVILNQLTSRDAGF 438
            +  ++ C  EGA   +     D           +   L EP +G   +++   +  D G 
Sbjct: 6123 EDAQFTCTIEGAPYPQIRWYKDGALLTTGN---KFQTLSEPRSGLLVLVIRAASKEDLGL 6179

Query: 439  YWC-LTNGDTLWRTTVEIKI 457
            Y C L N     R + E++I
Sbjct: 6180 YECELVNRLGSARASAELRI 6199



 Score = 34.3 bits (77), Expect = 0.45
 Identities = 33/134 (24%), Positives = 54/134 (40%), Gaps = 30/134 (22%)

Query: 204  SVVINQLRLSDAGQYLCQAGDDSNSNKKNAD------LQVLKPEPELVYEDLRGSVTFHC 257
            ++ ++  ++ D+  Y C+ G +        +       ++L+P    V  +L G+VT  C
Sbjct: 1775 TLTVHGAQVLDSAIYSCRVGAEGQDFPVQVEEVAAKFCRLLEP----VCGELGGTVTLAC 1830

Query: 258  ALGPEVANVAKFLCRQSSGENCDVVVNTLGKRAPAF-EGRILLNPQDKDGSFSVVITGLR 316
             L P  A V            C      +GKR     EG +           S+ + GLR
Sbjct: 1831 ELSPACAEVVW---------RCGNTQLRVGKRFQMVAEGPVR----------SLTVLGLR 1871

Query: 317  KEDAGRYLCGAHSD 330
             EDAG Y+C +  D
Sbjct: 1872 AEDAGEYVCESRDD 1885



 Score = 32.7 bits (73), Expect = 1.3
 Identities = 56/291 (19%), Positives = 108/291 (37%), Gaps = 43/291 (14%)

Query: 97   IAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGPGLLNDTKVY----TVDLGRTVTINC 152
            + Q+ + D+G Y C  G    G      L +++   +    ++       + G + T++C
Sbjct: 1225 VQQVGKADAGEYSCEAG----GQRVSFQLHITEPKAVFAKEQLVHNEVRTEAGASATLSC 1280

Query: 153  PFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQGTGQLLFSVVINQLRL 212
              +   AQ   + YK         + SS  V     G +R            +V+ Q   
Sbjct: 1281 --EVAQAQTEVTWYKD-----GKKLSSSSKVRIEAAGCMR-----------QLVVQQAGQ 1322

Query: 213  SDAGQYLCQAGDDSNSNKKNADLQVLKPEPELVYEDLRGSVTFHCALGPEVANVAKFLCR 272
            +DAG+Y C+AG      + +  L V +P+     E L      H  +  E   +A   C 
Sbjct: 1323 ADAGEYTCEAG----GQRLSFHLDVSEPKAVFAKEQLA-----HRKVQAEAGAIATLSCE 1373

Query: 273  QSSGENCDVVVNTLGKRAPAFEGRILLNPQDKDGSFSVVITGLRKEDAGRYLCGAHSDGQ 332
             +  +  +V     GK+         +  +    +  +V+    + D G Y C A    +
Sbjct: 1374 VAQAQT-EVTWYKDGKK---LSSSSKVRMEAVGCTRRLVVQQACQADTGEYSCEAGGQ-R 1428

Query: 333  LQEGSPIQAWQLFVNEESTIPRSPTVVKGVAGGSVAVLCPYNRKESKSIKY 383
            L     +   ++   +E  + R    V+  AG S  + C   + +++ + Y
Sbjct: 1429 LSFSLDVAEPKVVFAKEQPVHRE---VQAQAGASTTLSCEVAQAQTEVMWY 1476



 Score = 32.3 bits (72), Expect = 1.7
 Identities = 33/125 (26%), Positives = 54/125 (43%), Gaps = 24/125 (19%)

Query: 205  VVINQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKPEPELVYEDLR----GSVTFHCALG 260
            ++I    L D+G+Y C+AG   +S+      + ++ +  L  +DL     G+ T  C L 
Sbjct: 3152 LLITGATLQDSGRYKCEAGGACSSSIVRVHARPVRFQEAL--KDLEVLEGGAATLRCVLS 3209

Query: 261  PEVANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLNPQDKDGSFSVVITGLRKEDA 320
               A V     +   G N   V+    K +   EG +L           +V+  LR +D+
Sbjct: 3210 SVAAPV-----KWCYGNN---VLRPGDKYSLRQEGAML----------ELVVRNLRPQDS 3251

Query: 321  GRYLC 325
            GRY C
Sbjct: 3252 GRYSC 3256



 Score = 30.8 bits (68), Expect = 4.9
 Identities = 55/239 (23%), Positives = 90/239 (37%), Gaps = 35/239 (14%)

Query: 89   ENGTFVVNIAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGPGLLNDTKVYTVDLGRTV 148
            E  T  + I+ L + DS  Y C +G   +  S    L   +   ++ D +   V  G + 
Sbjct: 2966 EGLTLRLTISALEKADSDTYTCDIG---QAQSRAQLLVQGRRVHIIEDLEDVDVQEGSSA 3022

Query: 149  TINCPFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQGTGQLLFSVVIN 208
            T  C     N +            PV        ++ N    I  D Q  G  + +  + 
Sbjct: 3023 TFRCRISPANYE------------PVHWFLDKTPLHANELNEI--DAQPGGYHVLT--LR 3066

Query: 209  QLRLSDAGQYLCQAGDDSNSNKKNADLQVLKPEPELVYEDLRGSVTFHCALGPEVANVAK 268
            QL L D+G    +AGD     + +A L+V + +P +   +L  +       G ++  V  
Sbjct: 3067 QLALKDSGTIYFEAGDQ----RASAALRVTE-KPSVFSRELTDATITE---GEDLTLV-- 3116

Query: 269  FLCRQSSGENCDVVVNTLGKRAPAFEGRILLNPQDKDGSFSVVITGLRKEDAGRYLCGA 327
              C  S+   CD+ V    K      G        +     ++ITG   +D+GRY C A
Sbjct: 3117 --CETST---CDIPV-CWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKCEA 3169



 Score = 30.8 bits (68), Expect = 4.9
 Identities = 49/217 (22%), Positives = 75/217 (34%), Gaps = 47/217 (21%)

Query: 16   ISTKSPIFGPE--EVNSVEGNSVSITCYYPPTSVNRHTRKYWCRQGA--RGGCITLISSE 71
            ++ K  +F  E  +    EG  +++ C      +       W + G   RG     +S E
Sbjct: 3091 VTEKPSVFSRELTDATITEGEDLTLVCETSTCDIP----VCWTKDGKTLRGSARCQLSHE 3146

Query: 72   GYVSSKYAGRANLTNFPENGTFVVNIAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGP 131
            G+       RA L            I   +  DSGRYKC  G         V     +  
Sbjct: 3147 GH-------RAQLL-----------ITGATLQDSGRYKCEAGGACSSSIVRVHARPVRFQ 3188

Query: 132  GLLNDTKVYTVDLGRTVTINCPFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRI 191
              L D +V     G   T+ C   +  A             PV     +  + P     +
Sbjct: 3189 EALKDLEVLE---GGAATLRCVLSSVAA-------------PVKWCYGNNVLRPGDKYSL 3232

Query: 192  RLDIQGTGQLLFSVVINQLRLSDAGQYLCQAGDDSNS 228
            R +    G +L  +V+  LR  D+G+Y C  GD + S
Sbjct: 3233 RQE----GAML-ELVVRNLRPQDSGRYSCSFGDQTTS 3264



 Score = 30.4 bits (67), Expect = 6.4
 Identities = 38/173 (21%), Positives = 74/173 (42%), Gaps = 27/173 (15%)

Query: 97   IAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGPGLLND----TKVYTVDLGRTVTINC 152
            + Q  Q  +G Y C  G  S+ LSF   L V++   +       ++    + G + T++C
Sbjct: 1501 VQQAGQAVAGEYSCEAG--SQRLSFH--LHVAEPKAVFAKEQPASREVQAEAGTSATLSC 1556

Query: 153  PFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQGTGQLLFSVVINQLRL 212
              +   AQ   + YK                  + + ++R++  G  + L   V+ +   
Sbjct: 1557 --EVAQAQTEVTWYKD-------------GKKLSSSSKVRMEAVGCTRRL---VVQEAGQ 1598

Query: 213  SDAGQYLCQAGDDSNS-NKKNADLQVLKPEPELVYEDLRGSVTFHCALGPEVA 264
            +DAG+Y C+AGD   S +   A+ +V+  + +  + +++        L  EVA
Sbjct: 1599 ADAGEYSCKAGDQRLSFHLHVAEPKVVFAKEQPAHREVQAEAGASATLSCEVA 1651



 Score = 30.0 bits (66), Expect = 8.4
 Identities = 27/98 (27%), Positives = 39/98 (39%), Gaps = 19/98 (19%)

Query: 126 EVSQGPGLLNDTKVYTVDLGRTVTINCPFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNP 185
           + S  P  L   K + V +G+  T++C               QI   P   +       P
Sbjct: 5   QFSGAPRFLTRPKAFVVSVGKDATLSC---------------QIVGNPTPQVSWEKDQQP 49

Query: 186 NYTG-RIRLDIQGTGQLLFSVVINQLRLSDAGQYLCQA 222
              G R RL   G    L+ + I  L L D+GQY+C+A
Sbjct: 50  VAAGARFRLAQDGD---LYRLTILDLALGDSGQYVCRA 84



 Score = 30.0 bits (66), Expect = 8.4
 Identities = 58/238 (24%), Positives = 80/238 (33%), Gaps = 57/238 (23%)

Query: 97   IAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGPGLLNDTKVYTVDLGRTVTINCPF-K 155
            +  L   DSGRY C  G  +   +  V+   +Q  G L + +      G T T+ C   K
Sbjct: 3243 VRNLRPQDSGRYSCSFGDQTTSATLTVTALPAQFIGKLRNKEATE---GATATLRCELSK 3299

Query: 156  TENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQGTGQLLFSVVINQLRLSDA 215
                + RK            + D   Y          L I+G            L + DA
Sbjct: 3300 AAPVEWRKG--------SETLRDGDRYCLRQDGAMCELQIRG------------LAMVDA 3339

Query: 216  GQYLCQAGDDSNSNKKNADLQVLKPEPELVYEDLRGSVTFHCALGPEVANVAKFLCRQSS 275
             +Y C  G++  S    A L  ++P P      LR   +   A        A   C    
Sbjct: 3340 AEYSCVCGEERTS----ASL-TIRPMPAHFIGRLRHQESIEGA-------TATLRCE--- 3384

Query: 276  GENCDVVVNTLGKRAPA--FEGRILLNPQDK-----DGSF-SVVITGLRKEDAGRYLC 325
                      L K AP    +GR  L   D+     DG+   + I GL   DAG Y C
Sbjct: 3385 ----------LSKAAPVEWRKGRESLRDGDRHSLRQDGAVCELQICGLAVADAGEYSC 3432


>gi|148833506 obscurin, cytoskeletal calmodulin and titin-interacting
            RhoGEF isoform b [Homo sapiens]
          Length = 7968

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 102/456 (22%), Positives = 165/456 (36%), Gaps = 94/456 (20%)

Query: 95   VNIAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGPGLLNDTKVYTVDLGRTVTINCPF 154
            + I  LS  D+G Y C  G      +  V    +  P      +    + G T T+ C  
Sbjct: 3857 LQIHGLSVADTGEYSCVCGQERTSATLTVR---APQPVFREPLQSLQAEEGSTATLQCEL 3913

Query: 155  KTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQG-TGQLLFSVVINQLRLS 213
                A                V+ S G +     GR    +QG T +L    V+  L+  
Sbjct: 3914 SEPTAT---------------VVWSKGGLQLQANGRREPRLQGCTAEL----VLQDLQRE 3954

Query: 214  DAGQYLCQAGDDSNSNKKNADLQVLKPEPELVYEDLRGSVTFHCALGPEVANVAKFLCRQ 273
            D G+Y C  G  + S         ++   EL ++++    T H             LC +
Sbjct: 3955 DTGEYTCTCGSQATSATLTVTAAPVRFLRELQHQEVDEGGTAH-------------LCCE 4001

Query: 274  SSGENCDVVVNTLGKRAPAFEGRILLNPQDK-----DGSFS-VVITGLRKEDAGRYLCGA 327
             S     V            +G + L P  K     DG+ + +++ G+ +EDAG Y C  
Sbjct: 4002 LSRAGASVEWR---------KGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTCDT 4052

Query: 328  HSDGQLQEGSPIQAWQLFVNEESTIPRSPTVVKGV---AGGSVAVLCPYNRKESKSIKYW 384
               G  Q  + +             P+  T ++ +    G    + C  +  ES ++  W
Sbjct: 4053 ---GHTQSMASLSV-------RVPRPKFKTRLQSLEQETGDIARLCCQLSDAESGAVVQW 4102

Query: 385  CLWEGAQNGRCPLLVDSEGWVKAQYEGRLSLLEEPGNGTFTVILNQLTSRDAGFYWCLTN 444
             L EG +    P           +YE R          T  ++++QL ++D G Y C+T 
Sbjct: 4103 -LKEGVELHAGP-----------KYEMRSQ------GATRELLIHQLEAKDTGEYACVTG 4144

Query: 445  GDTLWRTTVEIKIIEGEPNLKVPGNVTAVLGETLKVPCHFPCKFSSYEKYWCKWNNTGCQ 504
            G    +T   +++ E E  + V G V A +  T      F C+ S       +W     Q
Sbjct: 4145 GQ---KTAASLRVTEPEVTI-VRGLVDAEV--TADEDVEFSCEVSRAGATGVQW---CLQ 4195

Query: 505  ALPSQDEGPSKAFVNCDENSRLVSLTLNLVTRADEG 540
             LP Q    ++  V    + R+ +L L  VT  D G
Sbjct: 4196 GLPLQSNEVTEVAV---RDGRIHTLRLKGVTPEDAG 4228



 Score = 39.7 bits (91), Expect = 0.011
 Identities = 97/463 (20%), Positives = 163/463 (35%), Gaps = 89/463 (19%)

Query: 28   VNSVEGNSVSITCYYPPTSVNRHTRKYWCRQGARGGCITLISSEGYVSSKYAGRANLTNF 87
            V++V G      C     +   H   +W + G   G     S E ++      R  L   
Sbjct: 807  VDAVAGGPAQFEC----ETSEAHVHVHWYKDGMELGH----SGERFLQEDVGTRHRLV-- 856

Query: 88   PENGTFVVNIAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGPGLLNDTKV----YTVD 143
                      A +++ D G Y C +G +S     D  L VS+   +    ++       +
Sbjct: 857  ---------AATVTRQDEGTYSCRVGEDS----VDFRLRVSEPKVVFAKEQLARRKLQAE 903

Query: 144  LGRTVTINCPFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQGTGQLLF 203
             G + T++C  +   AQ   + YK         + SS  V    TG  R           
Sbjct: 904  AGASATLSC--EVAQAQTEVTWYKD-----GKKLSSSSKVCMEATGCTR----------- 945

Query: 204  SVVINQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKPEPELVYEDLRGSVTFHCALGPEV 263
             +V+ Q   +DAG+Y C+AG      + +  L V   EP++V+         H  +  E 
Sbjct: 946  RLVVQQAGQADAGEYSCEAG----GQRLSFHLDV--KEPKVVFAK---DQVAHSEVQAEA 996

Query: 264  ANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLNPQDKDGSFSVVITGLRKEDAGRY 323
               A   C  +  +  +V+    GK+       + ++ + K     +V+    K DAG Y
Sbjct: 997  GASATLSCEVAQAQT-EVMWYKDGKK---LSSSLKVHVEAKGCRRRLVVQQAGKTDAGDY 1052

Query: 324  LCGAHSDGQLQEGSPIQAWQLFVNEESTIPRSPTVVKGVAGGSVAVLCPYNRKESKSIKY 383
             C A            +   +F  E+S        V+  AG S  + C   + +++   Y
Sbjct: 1053 SCEARGQRVSFRLHITEPKMMFAKEQSV----HNEVQAEAGASAMLSCEVAQAQTEVTWY 1108

Query: 384  WCLWEGAQNGRCPLLVDSEGWVKAQYEGRLSLLEEPGNGTFTVILNQLTSRDAGFYWCLT 443
                   ++G+    + S   V  + +G           T  ++L Q    DAG Y C  
Sbjct: 1109 -------KDGK---KLSSSSKVGMEVKG----------CTRRLVLPQAGKADAGEYSCEA 1148

Query: 444  NGDTLWRTTVEIKIIEGE----PNLKVPGNVTAVLGETLKVPC 482
             G    R +  + I E +        V   V A  G T  + C
Sbjct: 1149 GGQ---RVSFHLHITEPKGVFAKEQSVHNEVQAEAGTTAMLSC 1188



 Score = 36.6 bits (83), Expect = 0.090
 Identities = 45/181 (24%), Positives = 71/181 (39%), Gaps = 26/181 (14%)

Query: 92   TFVVNIAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGPGLLNDTKVYTVDLGRTVTIN 151
            T  V+ AQ+   DS  Y C +G   +     V    ++   LL        +LG TVT+ 
Sbjct: 1775 TLTVHGAQVL--DSAIYSCRVGAEGQDFPVQVEEVAAKFCRLLEPV---CGELGGTVTLA 1829

Query: 152  CPFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQGTGQLLFSVVINQLR 211
            C      A+               V+   G        R ++  +G  +   S+ +  LR
Sbjct: 1830 CELSPACAE---------------VVWRCGNTQLRVGKRFQMVAEGPVR---SLTVLGLR 1871

Query: 212  LSDAGQYLCQAGDDSNSNKKNADL-QVLKPEPEL--VYEDLRGSVTFHCALGPEVANVAK 268
              DAG+Y+C++ DD  S +    + +V+K    L  V  +  G  TF C + P    V  
Sbjct: 1872 AEDAGEYVCESRDDHTSAQLTVSVPRVVKFMSGLSTVVAEEGGEATFQCVVSPSDVAVVW 1931

Query: 269  F 269
            F
Sbjct: 1932 F 1932



 Score = 35.8 bits (81), Expect = 0.15
 Identities = 50/247 (20%), Positives = 94/247 (38%), Gaps = 55/247 (22%)

Query: 27   EVNSVEGNSVSITCYYPPTSVNRHTRKYWCRQGARGGCITLISSEGYVSSKYAGRANLTN 86
            EV +  G S  ++C          T   W + G +      +SS   V  +  G      
Sbjct: 1083 EVQAEAGASAMLSCEV----AQAQTEVTWYKDGKK------LSSSSKVGMEVKGCTRRLV 1132

Query: 87   FPENGTFVVNIAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGPGLL-NDTKVYT---V 142
             P+ G          + D+G Y C  G    G      L +++  G+   +  V+     
Sbjct: 1133 LPQAG----------KADAGEYSCEAG----GQRVSFHLHITEPKGVFAKEQSVHNEVQA 1178

Query: 143  DLGRTVTINCPFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQGTGQLL 202
            + G T  ++C  +    Q   + YK                  + + ++R++++G  + L
Sbjct: 1179 EAGTTAMLSC--EVAQPQTEVTWYKD-------------GKKLSSSSKVRMEVKGCTRRL 1223

Query: 203  FSVVINQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKP-----EPELVYEDLRGSVTFHC 257
               V+ Q+  +DAG+Y C+AG      + +  L + +P     + +LV+ ++R       
Sbjct: 1224 ---VVQQVGKADAGEYSCEAG----GQRVSFQLHITEPKAVFAKEQLVHNEVRTEAGASA 1276

Query: 258  ALGPEVA 264
             L  EVA
Sbjct: 1277 TLSCEVA 1283



 Score = 35.8 bits (81), Expect = 0.15
 Identities = 46/200 (23%), Positives = 74/200 (37%), Gaps = 30/200 (15%)

Query: 262  EVANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLNPQDKDGSFSVVITGLRKEDAG 321
            E+    K  CR +      +     GK        IL+  +D DGS ++++  L   D+G
Sbjct: 6026 ELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILI--EDPDGSCALILDSLTGVDSG 6083

Query: 322  RYLC-GAHSDGQLQEGSPI--QAWQLFVNEESTIPRSPTVVKGVAGGSVAVLCPYNRKES 378
            +Y+C  A + G       I  Q    FVN+   +  SP V                  E 
Sbjct: 6084 QYMCFAASAAGNCSTLGKILVQVPPRFVNK---VRASPFV------------------EG 6122

Query: 379  KSIKYWCLWEGAQNGRCPLLVDSEGWVKAQYEGRLSLLEEPGNGTFTVILNQLTSRDAGF 438
            +  ++ C  EGA   +     D           +   L EP +G   +++   +  D G 
Sbjct: 6123 EDAQFTCTIEGAPYPQIRWYKDGALLTTGN---KFQTLSEPRSGLLVLVIRAASKEDLGL 6179

Query: 439  YWC-LTNGDTLWRTTVEIKI 457
            Y C L N     R + E++I
Sbjct: 6180 YECELVNRLGSARASAELRI 6199



 Score = 34.3 bits (77), Expect = 0.45
 Identities = 33/134 (24%), Positives = 54/134 (40%), Gaps = 30/134 (22%)

Query: 204  SVVINQLRLSDAGQYLCQAGDDSNSNKKNAD------LQVLKPEPELVYEDLRGSVTFHC 257
            ++ ++  ++ D+  Y C+ G +        +       ++L+P    V  +L G+VT  C
Sbjct: 1775 TLTVHGAQVLDSAIYSCRVGAEGQDFPVQVEEVAAKFCRLLEP----VCGELGGTVTLAC 1830

Query: 258  ALGPEVANVAKFLCRQSSGENCDVVVNTLGKRAPAF-EGRILLNPQDKDGSFSVVITGLR 316
             L P  A V            C      +GKR     EG +           S+ + GLR
Sbjct: 1831 ELSPACAEVVW---------RCGNTQLRVGKRFQMVAEGPVR----------SLTVLGLR 1871

Query: 317  KEDAGRYLCGAHSD 330
             EDAG Y+C +  D
Sbjct: 1872 AEDAGEYVCESRDD 1885



 Score = 32.7 bits (73), Expect = 1.3
 Identities = 56/291 (19%), Positives = 108/291 (37%), Gaps = 43/291 (14%)

Query: 97   IAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGPGLLNDTKVY----TVDLGRTVTINC 152
            + Q+ + D+G Y C  G    G      L +++   +    ++       + G + T++C
Sbjct: 1225 VQQVGKADAGEYSCEAG----GQRVSFQLHITEPKAVFAKEQLVHNEVRTEAGASATLSC 1280

Query: 153  PFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQGTGQLLFSVVINQLRL 212
              +   AQ   + YK         + SS  V     G +R            +V+ Q   
Sbjct: 1281 --EVAQAQTEVTWYKD-----GKKLSSSSKVRIEAAGCMR-----------QLVVQQAGQ 1322

Query: 213  SDAGQYLCQAGDDSNSNKKNADLQVLKPEPELVYEDLRGSVTFHCALGPEVANVAKFLCR 272
            +DAG+Y C+AG      + +  L V +P+     E L      H  +  E   +A   C 
Sbjct: 1323 ADAGEYTCEAG----GQRLSFHLDVSEPKAVFAKEQLA-----HRKVQAEAGAIATLSCE 1373

Query: 273  QSSGENCDVVVNTLGKRAPAFEGRILLNPQDKDGSFSVVITGLRKEDAGRYLCGAHSDGQ 332
             +  +  +V     GK+         +  +    +  +V+    + D G Y C A    +
Sbjct: 1374 VAQAQT-EVTWYKDGKK---LSSSSKVRMEAVGCTRRLVVQQACQADTGEYSCEAGGQ-R 1428

Query: 333  LQEGSPIQAWQLFVNEESTIPRSPTVVKGVAGGSVAVLCPYNRKESKSIKY 383
            L     +   ++   +E  + R    V+  AG S  + C   + +++ + Y
Sbjct: 1429 LSFSLDVAEPKVVFAKEQPVHRE---VQAQAGASTTLSCEVAQAQTEVMWY 1476



 Score = 32.3 bits (72), Expect = 1.7
 Identities = 33/125 (26%), Positives = 54/125 (43%), Gaps = 24/125 (19%)

Query: 205  VVINQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKPEPELVYEDLR----GSVTFHCALG 260
            ++I    L D+G+Y C+AG   +S+      + ++ +  L  +DL     G+ T  C L 
Sbjct: 3152 LLITGATLQDSGRYKCEAGGACSSSIVRVHARPVRFQEAL--KDLEVLEGGAATLRCVLS 3209

Query: 261  PEVANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLNPQDKDGSFSVVITGLRKEDA 320
               A V     +   G N   V+    K +   EG +L           +V+  LR +D+
Sbjct: 3210 SVAAPV-----KWCYGNN---VLRPGDKYSLRQEGAML----------ELVVRNLRPQDS 3251

Query: 321  GRYLC 325
            GRY C
Sbjct: 3252 GRYSC 3256



 Score = 30.8 bits (68), Expect = 4.9
 Identities = 55/239 (23%), Positives = 90/239 (37%), Gaps = 35/239 (14%)

Query: 89   ENGTFVVNIAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGPGLLNDTKVYTVDLGRTV 148
            E  T  + I+ L + DS  Y C +G   +  S    L   +   ++ D +   V  G + 
Sbjct: 2966 EGLTLRLTISALEKADSDTYTCDIG---QAQSRAQLLVQGRRVHIIEDLEDVDVQEGSSA 3022

Query: 149  TINCPFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQGTGQLLFSVVIN 208
            T  C     N +            PV        ++ N    I  D Q  G  + +  + 
Sbjct: 3023 TFRCRISPANYE------------PVHWFLDKTPLHANELNEI--DAQPGGYHVLT--LR 3066

Query: 209  QLRLSDAGQYLCQAGDDSNSNKKNADLQVLKPEPELVYEDLRGSVTFHCALGPEVANVAK 268
            QL L D+G    +AGD     + +A L+V + +P +   +L  +       G ++  V  
Sbjct: 3067 QLALKDSGTIYFEAGDQ----RASAALRVTE-KPSVFSRELTDATITE---GEDLTLV-- 3116

Query: 269  FLCRQSSGENCDVVVNTLGKRAPAFEGRILLNPQDKDGSFSVVITGLRKEDAGRYLCGA 327
              C  S+   CD+ V    K      G        +     ++ITG   +D+GRY C A
Sbjct: 3117 --CETST---CDIPV-CWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKCEA 3169



 Score = 30.8 bits (68), Expect = 4.9
 Identities = 49/217 (22%), Positives = 75/217 (34%), Gaps = 47/217 (21%)

Query: 16   ISTKSPIFGPE--EVNSVEGNSVSITCYYPPTSVNRHTRKYWCRQGA--RGGCITLISSE 71
            ++ K  +F  E  +    EG  +++ C      +       W + G   RG     +S E
Sbjct: 3091 VTEKPSVFSRELTDATITEGEDLTLVCETSTCDIP----VCWTKDGKTLRGSARCQLSHE 3146

Query: 72   GYVSSKYAGRANLTNFPENGTFVVNIAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGP 131
            G+       RA L            I   +  DSGRYKC  G         V     +  
Sbjct: 3147 GH-------RAQLL-----------ITGATLQDSGRYKCEAGGACSSSIVRVHARPVRFQ 3188

Query: 132  GLLNDTKVYTVDLGRTVTINCPFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRI 191
              L D +V     G   T+ C   +  A             PV     +  + P     +
Sbjct: 3189 EALKDLEVLE---GGAATLRCVLSSVAA-------------PVKWCYGNNVLRPGDKYSL 3232

Query: 192  RLDIQGTGQLLFSVVINQLRLSDAGQYLCQAGDDSNS 228
            R +    G +L  +V+  LR  D+G+Y C  GD + S
Sbjct: 3233 RQE----GAML-ELVVRNLRPQDSGRYSCSFGDQTTS 3264



 Score = 30.4 bits (67), Expect = 6.4
 Identities = 38/173 (21%), Positives = 74/173 (42%), Gaps = 27/173 (15%)

Query: 97   IAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGPGLLND----TKVYTVDLGRTVTINC 152
            + Q  Q  +G Y C  G  S+ LSF   L V++   +       ++    + G + T++C
Sbjct: 1501 VQQAGQAVAGEYSCEAG--SQRLSFH--LHVAEPKAVFAKEQPASREVQAEAGTSATLSC 1556

Query: 153  PFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQGTGQLLFSVVINQLRL 212
              +   AQ   + YK                  + + ++R++  G  + L   V+ +   
Sbjct: 1557 --EVAQAQTEVTWYKD-------------GKKLSSSSKVRMEAVGCTRRL---VVQEAGQ 1598

Query: 213  SDAGQYLCQAGDDSNS-NKKNADLQVLKPEPELVYEDLRGSVTFHCALGPEVA 264
            +DAG+Y C+AGD   S +   A+ +V+  + +  + +++        L  EVA
Sbjct: 1599 ADAGEYSCKAGDQRLSFHLHVAEPKVVFAKEQPAHREVQAEAGASATLSCEVA 1651



 Score = 30.0 bits (66), Expect = 8.4
 Identities = 27/98 (27%), Positives = 39/98 (39%), Gaps = 19/98 (19%)

Query: 126 EVSQGPGLLNDTKVYTVDLGRTVTINCPFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNP 185
           + S  P  L   K + V +G+  T++C               QI   P   +       P
Sbjct: 5   QFSGAPRFLTRPKAFVVSVGKDATLSC---------------QIVGNPTPQVSWEKDQQP 49

Query: 186 NYTG-RIRLDIQGTGQLLFSVVINQLRLSDAGQYLCQA 222
              G R RL   G    L+ + I  L L D+GQY+C+A
Sbjct: 50  VAAGARFRLAQDGD---LYRLTILDLALGDSGQYVCRA 84



 Score = 30.0 bits (66), Expect = 8.4
 Identities = 58/238 (24%), Positives = 80/238 (33%), Gaps = 57/238 (23%)

Query: 97   IAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGPGLLNDTKVYTVDLGRTVTINCPF-K 155
            +  L   DSGRY C  G  +   +  V+   +Q  G L + +      G T T+ C   K
Sbjct: 3243 VRNLRPQDSGRYSCSFGDQTTSATLTVTALPAQFIGKLRNKEATE---GATATLRCELSK 3299

Query: 156  TENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQGTGQLLFSVVINQLRLSDA 215
                + RK            + D   Y          L I+G            L + DA
Sbjct: 3300 AAPVEWRKG--------SETLRDGDRYCLRQDGAMCELQIRG------------LAMVDA 3339

Query: 216  GQYLCQAGDDSNSNKKNADLQVLKPEPELVYEDLRGSVTFHCALGPEVANVAKFLCRQSS 275
             +Y C  G++  S    A L  ++P P      LR   +   A        A   C    
Sbjct: 3340 AEYSCVCGEERTS----ASL-TIRPMPAHFIGRLRHQESIEGA-------TATLRCE--- 3384

Query: 276  GENCDVVVNTLGKRAPA--FEGRILLNPQDK-----DGSF-SVVITGLRKEDAGRYLC 325
                      L K AP    +GR  L   D+     DG+   + I GL   DAG Y C
Sbjct: 3385 ----------LSKAAPVEWRKGRESLRDGDRHSLRQDGAVCELQICGLAVADAGEYSC 3432


>gi|55953135 immunoglobulin superfamily, member 3 isoform 2 [Homo
           sapiens]
          Length = 1194

 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 120/552 (21%), Positives = 206/552 (37%), Gaps = 100/552 (18%)

Query: 5   VLTCLLAVFPAISTKSPIFGPE-EVNSVEGNSVSITC----YYPPTSVNRHTRKYWCRQG 59
           VL+CL AV   +S +  +   E  +   EG+ ++I C    Y  P+  N     Y     
Sbjct: 7   VLSCL-AVLGVVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIYLPSSP 65

Query: 60  ARGGCITLISSEGYVSSKYA-----GRANLTNFPENGTFVVNIAQLSQDDSGRYKCGLGI 114
            R   I       +  + Y      G+  +     N T +++I  L   D+G Y+C    
Sbjct: 66  EREVQIVSTMDSSFPYAIYTQRVRGGKIFIERVQGNST-LLHITDLQARDAGEYECHTPS 124

Query: 115 NSRGL--SFDVSLEVSQGPGLLNDTKVYTVDLGRT----VTINCPFKTENAQKRKS---- 164
             +    S+   + +   P  L  T +    L R     + + C   +E  Q        
Sbjct: 125 TDKQYFGSYSAKMNLVVIPDSLQTTAMPQT-LHRVEQDPLELTCEVASETIQHSHLSVAW 183

Query: 165 LYKQIGLYPVLVID---------SSGYVNPNYTGRIRLDIQGTGQLLFSVVINQLRLSDA 215
           L +++G  PV VI          SS Y      G +RLD    G+  F + I  L+ SD 
Sbjct: 184 LRQKVGEKPVEVISLSRDFMLHSSSEYAQRQSLGEVRLD--KLGRTTFRLTIFHLQPSDQ 241

Query: 216 GQYLCQAGD---DSNSN-----KKNADLQVLKPEP-----------ELVYEDLRGSVTFH 256
           G++ C+A +   D + +     +K ++  V+  +P           E     +   V F 
Sbjct: 242 GEFYCEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETEKRLHTVGEPVEFR 301

Query: 257 CALGPEVANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRI--------LLNPQDKDGSF 308
           C L  E  NV       S   N  ++        P              L   ++ D  F
Sbjct: 302 CIL--EAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSVF 359

Query: 309 SVVITGLRKEDAGRYLCGAHSDGQLQEGSPIQAWQLFVNEESTIPRSPTVVKGVAGGSVA 368
            + I  LR+ED+G+Y C      +   G        F+++ES  P++  ++      S++
Sbjct: 360 VLKIYHLRQEDSGKYNCRVTEREKTVTGE-------FIDKESKRPKNIPIIVLPLKSSIS 412

Query: 369 VLCPYNRK---ESKSIKYWC--------------LWE--GAQNGRCPLL-VDSEGWVK-- 406
           V    N     E + +++ C              +W+    QN R  ++ +D +G V+  
Sbjct: 413 VEVASNASVILEGEDLRFSCSVRTAGRPQGRFSVIWQLVDRQNRRSNIMWLDRDGTVQPG 472

Query: 407 AQYEGRLSL----LEEPGNGTFTVILNQLTSRDAGFYWCLTNGDTLWRTTVEIK-IIEGE 461
           + Y  R S     +E+    +F++ +      D G Y C     T W   V+ +  I GE
Sbjct: 473 SSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECHV---TEWVRAVDGEWQIVGE 529

Query: 462 PNLKVPGNVTAV 473
                P ++TA+
Sbjct: 530 RRASTPISITAL 541



 Score = 30.0 bits (66), Expect = 8.4
 Identities = 42/163 (25%), Positives = 62/163 (38%), Gaps = 34/163 (20%)

Query: 306 GSFSVVITGLRKEDAGRYLCGAHSDGQLQEGSPIQAWQLFVNEESTIPRSPTVVK----- 360
           G FS+ +      D+G Y C  H +  L   SP  AW     E S   R+   VK     
Sbjct: 763 GLFSLTVQRAEVSDSGSYYC--HVEEWLL--SPNYAWYKLAEEVSG--RTEVTVKQPDSR 816

Query: 361 ---GVAGGSVAVL---------CPYNRKE--SKSIKYWCLWEG--------AQNGRCPLL 398
                A G+++VL            NR    S+ +  W +W+         A+  R    
Sbjct: 817 LRLSQAQGNLSVLETRQVQLECVVLNRTSITSQLMVEWFVWKPNHPERETVARLSRDATF 876

Query: 399 VDSEGWVKAQYEGRLSLLEEPGNGTFTVILNQLTSRDAGFYWC 441
              E   K   +GRL L E P  G + + +  +  +D+G Y C
Sbjct: 877 HYGEQAAKNNLKGRLHL-ESPSPGVYRLFIQNVAVQDSGTYSC 918


>gi|118572606 hemicentin 1 [Homo sapiens]
          Length = 5635

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 115/536 (21%), Positives = 191/536 (35%), Gaps = 97/536 (18%)

Query: 20   SPIFG--PEEVNSVEGNSVSITCYYPPTSVNRHTRKYWCRQGARGGCITLISSEGYVSSK 77
            +P+ G  P   N +EG  +++ C     + N    + W +  A      ++    Y++ +
Sbjct: 889  APLIGISPSVANVIEGQQLTLPCTL--LAGNPIPERRWIKNSA------MLLQNPYITVR 940

Query: 78   YAGRANLTNFPENGTFVVNIAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGPGLLNDT 137
              G              ++I ++   D G Y C     +   +   S+ V   P + +  
Sbjct: 941  SDGS-------------LHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQ 987

Query: 138  KVYTVDLGRTVTINCPFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQG 197
            ++ +   G  VT+ C  K     K   ++ + G    L+  SS   +    G + +   G
Sbjct: 988  QILSTIEGIPVTLPC--KASGNPKPSVIWSKKG---ELISTSSAKFSAGADGSLYVVSPG 1042

Query: 198  TGQLLFSVVINQLRLSDAGQYLCQAGDDSNSNKKNADLQV-LKPEPELVYEDLRG----- 251
                            ++G+Y+C A + +   K+   L V ++P    V+ D RG     
Sbjct: 1043 G--------------EESGEYVCTATNTAGYAKRKVQLTVYVRPR---VFGDQRGLSQDK 1085

Query: 252  SVTFHCALGPEVANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLNPQDKDGSFSVV 311
             V      G EV       C   S     +      +    F  R    P     S S+ 
Sbjct: 1086 PVEISVLAGEEVT----LPCEVKSLPPPIITWAKETQLISPFSPRHTFLP-----SGSMK 1136

Query: 312  ITGLRKEDAGRYLCGAHSDGQLQEGSPIQAWQLFVNEESTIPRSPTVVKGVAGGSVAVLC 371
            IT  R  D+G YLC A +      G+  QA +L V+    I R P  +K   G  V + C
Sbjct: 1137 ITETRTSDSGMYLCVATNIA----GNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPC 1192

Query: 372  PYNRKESKSIKYWCLWEGAQNGRCPLLVDSEGWVKAQYEGRLSLLEEPGNGTFTVILNQL 431
                              AQ    P++  S+G      +G   +    G    T+ ++Q 
Sbjct: 1193 -----------------NAQGTPLPVITWSKGGSTMLVDGEHHVSNPDG----TLSIDQA 1231

Query: 432  TSRDAGFYWCLTN---GDTLWRTTVEIKIIEGEPNLKVPGNVTAVLGETLKVPCHFPCKF 488
            T  DAG Y C+     G      T+ ++      +L+ P N T            FPC  
Sbjct: 1232 TPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYN-TTFQERVANQRIEFPCPA 1290

Query: 489  SSYEKYWCKWNNTGCQALPSQDEGPSKAFVNCDENSRLVSLTLNLVTRADEGWYWC 544
                K   KW + G + L  ++ G     ++  E+  L  L +  VT  D G Y C
Sbjct: 1291 KGTPKPTIKWLHNG-RELTGREPG-----ISILEDGTL--LVIASVTPYDNGEYIC 1338



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 101/440 (22%), Positives = 162/440 (36%), Gaps = 104/440 (23%)

Query: 22   IFGP--EEVNSVEGNSVSITCY---YPPTSVNRHTRKYWCRQGARGGCITLISSEGYVSS 76
            + GP  E +  V  N +S+TC    +PP  ++                        ++ +
Sbjct: 2966 VIGPKSENLTVVVNNFISLTCEVSGFPPPDLS------------------------WLKN 3001

Query: 77   KYAGRANLTNFPENGTFVVNIAQLSQDDSGRYKCGLGINSRGLSFD-VSLEVSQGPGLLN 135
            +   + N       G   + I +    D G Y C + IN  G S    SL V   P + +
Sbjct: 3002 EQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTC-IAINQAGESKKKFSLTVYVPPSIKD 3060

Query: 136  ----DTKVYTVDLGRTVTINCPFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRI 191
                   V  V  G +V++ C     NA             PV+    +G +    T   
Sbjct: 3061 HDSESLSVVNVREGTSVSLECE---SNAVPP----------PVITWYKNGRM---ITEST 3104

Query: 192  RLDIQGTGQLLFSVVINQLRLSDAGQYLCQAGDDSNSNKKNADLQVL------KPEPELV 245
             ++I   GQ+L    I +  +SD GQY+C+A + +  + KN  L V        PE E++
Sbjct: 3105 HVEILADGQMLH---IKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVI 3161

Query: 246  YEDLRGSVTFHC-ALGPEVANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLNPQDK 304
             E +   VT  C A G     +A +L      EN D           + E RIL      
Sbjct: 3162 VETISNPVTLTCDATGIPPPTIA-WLKNHKRIENSD-----------SLEVRIL------ 3203

Query: 305  DGSFSVVITGLRKEDAGRYLCGAHSDGQLQEGSPIQAWQLFVNEESTIPRS--PTVVKGV 362
             G   + I   +  D+G Y C A +     EG   + + L +    ++  +  P+ V  +
Sbjct: 3204 SGGSKLQIARSQHSDSGNYTCIASN----MEGKAQKYYFLSIQVPPSVAGAEIPSDVSVL 3259

Query: 363  AGGSVAVLCPYNRKESKSIKYWCLWEGAQNGRCPLLVDSEGWVKAQYEGRLSLLEEPGNG 422
             G +V ++C  N   +  I++  L +G                K    G    +    NG
Sbjct: 3260 LGENVELVCNANGIPTPLIQW--LKDG----------------KPIASGETERIRVSANG 3301

Query: 423  TFTVILNQLTSRDAGFYWCL 442
            +   I   LTS D G Y C+
Sbjct: 3302 STLNIYGALTS-DTGKYTCV 3320



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 70/346 (20%), Positives = 138/346 (39%), Gaps = 54/346 (15%)

Query: 94   VVNIAQLSQDDSGRYKCGLGINSRGLS-FDVSLEVSQGPGLLNDTKVYTVDLGRTVTINC 152
            +++I      D+G YKC + INS G +    SL+V   P +     +  V +   V + C
Sbjct: 1975 IIDIESAQISDAGIYKC-VAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLEC 2033

Query: 153  PFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQGTGQLLFSVVINQLRL 212
              +   A             P L     G    +++    L +   G++L    +   ++
Sbjct: 2034 EARGIPA-------------PSLTWLKDGSPVSSFSNG--LQVLSGGRIL---ALTSAQI 2075

Query: 213  SDAGQYLCQAGDDSNSNKKNADLQVLKPEPELVYEDLRGSVTFHCALGPEVANVAKFLCR 272
            SD G+Y C A + +   +++ DL+V  P P ++ E+   SV         ++   + LC+
Sbjct: 2076 SDTGRYTCVAVNAAGEKQRDIDLRVYVP-PNIMGEEQNVSVL--------ISQAVELLCQ 2126

Query: 273  QSSGENCDVVVNTLGKRAPAFEGRILLNPQD---KDGSFSVVITGLRKEDAGRYLCGA-H 328
              +     +   TL       +G  LL        +    + I   + +D GRY C A +
Sbjct: 2127 SDA-----IPPPTL---TWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATN 2178

Query: 329  SDGQLQEGSPIQAWQLFVNEESTIPRSPTVVKGVAGGSVAVLCPYNRKESKSIKYWCLWE 388
              G+ ++   +  W   V          T +  + G  +++LC  +     ++    +W+
Sbjct: 2179 VAGKTEKNYNVNIW---VPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNL----IWK 2231

Query: 389  GAQNGRCPLLVDSEGWVKAQYEGR---LSLLEEPGNGTFTVILNQL 431
               +   P+L DS G V+    GR   +S+ E+     ++ + + +
Sbjct: 2232 KKGS---PVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNV 2274



 Score = 35.0 bits (79), Expect = 0.26
 Identities = 37/147 (25%), Positives = 61/147 (41%), Gaps = 27/147 (18%)

Query: 191  IRLDIQGTGQLLFS---VVINQLRLSDAGQYLCQAGDDSNSNKKNADLQ-----VLKPEP 242
            IRL  +G G  + S   + I   +L+ AG+Y C A + + S  ++  L      V++P+P
Sbjct: 3935 IRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQP 3994

Query: 243  ELVYEDLRGSVTFHCALGPEVANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLNPQ 302
              ++  L   +   C         + F+  Q  G N    VNT G+              
Sbjct: 3995 SELHVILNNPILLPC---EATGTPSPFITWQKEGIN----VNTSGRNHAVLP-------- 4039

Query: 303  DKDGSFSVVITGLRKEDAGRYLCGAHS 329
                S  + I+   +EDAG Y+C A +
Sbjct: 4040 ----SGGLQISRAVREDAGTYMCVAQN 4062



 Score = 33.5 bits (75), Expect = 0.76
 Identities = 81/362 (22%), Positives = 137/362 (37%), Gaps = 74/362 (20%)

Query: 94   VVNIAQLSQDDSGRYKCGLGINSRGLS---FDVSLEVSQGPGLLNDTKVYTVDLGRTVTI 150
            V+ I      D+GRY C    N  G +   ++V++ V    G  ++    TV  G  +++
Sbjct: 2158 VLKIEDAQVQDTGRYTCE-ATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISL 2216

Query: 151  NCPFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQGTGQLLFSVVINQL 210
             C  ++        ++K+ G  PVL          +  GR+R+ + G  QL  S+     
Sbjct: 2217 LC--ESSGIPPPNLIWKKKGS-PVLT---------DSMGRVRI-LSGGRQLQISIA---- 2259

Query: 211  RLSDAGQYLCQAGDDSNSNKKNADLQVLKPEPELVYEDLRGSVTFHCALGPEVANVAKFL 270
              SDA  Y C A + + + KK  +LQV           +R ++T   +   E+       
Sbjct: 2260 EKSDAALYSCVASNVAGTAKKEYNLQVY----------IRPTITNSGSHPTEII------ 2303

Query: 271  CRQSSGENCDVVVNTLGKRAPAF----EGRILLNPQD---KDGSFSVVITGLRKEDAGRY 323
               + G++  +     G   P      +G  L+  +     D    + +  +   D GRY
Sbjct: 2304 --VTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRY 2361

Query: 324  LCGAHSDGQLQEGSPIQAWQLFVNEESTI---PRSPTVVKGVAGGSVAVLCPYNRKESKS 380
            +C A +      G   + + L V+   +I    RSP  +  V   SV++ C     E+  
Sbjct: 2362 VCVAVN----VAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTC-----EASG 2412

Query: 381  IKYWCLWEGAQNGRCPLLVDSEGWVKAQYEGRLSLLEEPGNGTFTVILNQLTSRDAGFYW 440
            I                 + S  W K  +   LS      +G   + L Q T  DAG Y 
Sbjct: 2413 IP----------------LPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYT 2456

Query: 441  CL 442
            C+
Sbjct: 2457 CV 2458



 Score = 32.7 bits (73), Expect = 1.3
 Identities = 63/256 (24%), Positives = 94/256 (36%), Gaps = 67/256 (26%)

Query: 204  SVVINQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKPEPELVYEDLRGSVTFHCALGPEV 263
            S+ I + R SD+G YLC A + + +  +   L V  P                    P++
Sbjct: 1134 SMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVP--------------------PKI 1173

Query: 264  ANVAKFLCRQSSGENCDVVVNTLGKRAPAFE----GRILL-----NPQDKDGSFSVVITG 314
                K L +   G+  D+  N  G   P       G  +L     +  + DG+ S  I  
Sbjct: 1174 QRGPKHL-KVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLS--IDQ 1230

Query: 315  LRKEDAGRYLCGAHSDGQLQEGSPIQAWQLFVNEESTI-----PRSPTVVKGVAGGSVAV 369
                DAG Y C A +      G+      L V E  T+     P + T  + VA   +  
Sbjct: 1231 ATPSDAGIYTCVATNIA----GTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEF 1286

Query: 370  LCPYNRKESKSIKYWCLWEGAQNGRCPLLVDSEGWVKAQYEGR---LSLLEEPGNGTFTV 426
             CP       +IK+        NGR             +  GR   +S+LE+   GT  V
Sbjct: 1287 PCPAKGTPKPTIKW------LHNGR-------------ELTGREPGISILED---GTLLV 1324

Query: 427  ILNQLTSRDAGFYWCL 442
            I + +T  D G Y C+
Sbjct: 1325 IAS-VTPYDNGEYICV 1339



 Score = 32.3 bits (72), Expect = 1.7
 Identities = 42/146 (28%), Positives = 66/146 (45%), Gaps = 21/146 (14%)

Query: 94   VVNIAQLSQDDSGRYKCGLGINSRG-LSFDVSLEVSQGPGLLNDTKVYTVDLGRTVTINC 152
            V+ IA+   +D+GRY C +  N+ G     + L V + P L +  K+    L  TV ++ 
Sbjct: 1882 VLQIAKTLLEDAGRYTC-VATNAAGETQQHIQLHVHEPPSLEDAGKM----LNETVLVSN 1936

Query: 153  PFKTENAQKRKSLYKQIGLYPVLVIDSSGYV-NPNYTGRIRLDIQGTGQLLFSVVINQLR 211
            P + E         K  G  PV VI  + Y  N   +G   +     GQ+   + I   +
Sbjct: 1937 PVQLE--------CKAAG-NPVPVI--TWYKDNRLLSGSTSMTFLNRGQI---IDIESAQ 1982

Query: 212  LSDAGQYLCQAGDDSNSNKKNADLQV 237
            +SDAG Y C A + + + +    LQV
Sbjct: 1983 ISDAGIYKCVAINSAGATELFYSLQV 2008



 Score = 32.0 bits (71), Expect = 2.2
 Identities = 56/247 (22%), Positives = 90/247 (36%), Gaps = 48/247 (19%)

Query: 90   NGTFVVNIAQLSQDDSGRYKCGLGINSRGLSFDVS-LEVSQGPGLLNDTKVYTVD-LGRT 147
            NG   + I ++S++DSG Y C    NS G    +  + V + P    D     ++ LG  
Sbjct: 4308 NGHSELVIERVSKEDSGTYVC-TAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPLGGN 4366

Query: 148  VTINCPFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQGTGQLLFSVVI 207
              +NC  K +               P +  +  G V+   + RIR    G G L     +
Sbjct: 4367 AILNCEVKGDPT-------------PTIQWNRKG-VDIEISHRIRQ--LGNGSLAIYGTV 4410

Query: 208  NQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKP-----EPELVYEDLRGSVTFHCALGPE 262
            N+    DAG Y C A +++   +++  L +  P     EP     +  G +  +C    E
Sbjct: 4411 NE----DAGDYTCVATNEAGVVERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGE 4466

Query: 263  VANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLNPQDKDGSFSVVITGLRKEDAGR 322
                  +  RQ    + D  VN L                      S+ I   +KED   
Sbjct: 4467 PQPTITW-SRQGHSISWDDRVNVLSNN-------------------SLYIADAQKEDTSE 4506

Query: 323  YLCGAHS 329
            + C A +
Sbjct: 4507 FECVARN 4513



 Score = 30.8 bits (68), Expect = 4.9
 Identities = 35/136 (25%), Positives = 52/136 (38%), Gaps = 14/136 (10%)

Query: 430 QLTSRDAGFYWCLTNGDT-LWRTTVEIKIIEGEPNLKVPGNVTAVLGETLKVPCHFPCKF 488
           ++T  D GFY C+        R      + E  P ++VP NVT   GE   + C      
Sbjct: 488 KVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGERAVLTC-LIISA 546

Query: 489 SSYEKYWCKWNNTGCQALPSQDEGPSKAFVNCDENSRLVSLTLNLVTRADEGWYWCGVKQ 548
             Y   W + +     A P++     +   N       +SL L  V   D G Y C V  
Sbjct: 547 VDYNLTWQRNDRDVRLAEPAR----IRTLAN-------LSLELKSVKFNDAGEYHCMV-S 594

Query: 549 GHFYGETAAVYVAVEE 564
                  A+V++ V+E
Sbjct: 595 SEGGSSAASVFLTVQE 610



 Score = 30.8 bits (68), Expect = 4.9
 Identities = 33/124 (26%), Positives = 49/124 (39%), Gaps = 18/124 (14%)

Query: 209  QLRLSDAGQYLCQAGDDSNSNKKNADLQVLKPEPELVYEDLRGSVTFHCALGPEVANVAK 268
            Q  + DAGQY C   + +   +K   L VL P P +V E+    V              K
Sbjct: 2446 QTTMEDAGQYTCVVRNAAGEERKIFGLSVLVP-PHIVGENTLEDV--------------K 2490

Query: 269  FLCRQSSGENCDVVVNTLGKRAPAFEGRILLNPQDK---DGSFSVVITGLRKEDAGRYLC 325
               +QS    C+V  N + +     +G+ L   +      G   + IT ++    GRY C
Sbjct: 2491 VKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTC 2550

Query: 326  GAHS 329
             A S
Sbjct: 2551 LASS 2554



 Score = 30.8 bits (68), Expect = 4.9
 Identities = 40/158 (25%), Positives = 73/158 (46%), Gaps = 31/158 (19%)

Query: 91   GTFVVNIAQLSQDDSGRYKCGLGINSRG---LSFDVSLEVSQGPGLLNDT-----KVYTV 142
            G  V+ I +   +D+GRY C + +N  G   L +DV + V   P ++        +  TV
Sbjct: 2829 GGRVLQIPRAKVEDAGRYTC-VAVNEAGEDSLQYDVRVLV---PPIIKGANSDLPEEVTV 2884

Query: 143  DLGRTVTINCPFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQGTGQLL 202
             + ++  I C   +  +   ++ +++ G  P+L  D   +++    GRI L I  T    
Sbjct: 2885 LVNKSALIEC--LSSGSPAPRNSWQKDG-QPLLEDDHHKFLS---NGRI-LQILNT---- 2933

Query: 203  FSVVINQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKP 240
                    +++D G+Y+C A + + S KK  +L V  P
Sbjct: 2934 --------QITDIGRYVCVAENTAGSAKKYFNLNVHVP 2963



 Score = 30.8 bits (68), Expect = 4.9
 Identities = 24/99 (24%), Positives = 43/99 (43%), Gaps = 8/99 (8%)

Query: 148  VTINCPFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQGTGQLLFSVV- 206
            +T+N P   +   +  SL   +    VL   + G   P  T R    +       +S++ 
Sbjct: 3707 LTVNVPPNIKGGPQ--SLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILE 3764

Query: 207  -----INQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKP 240
                 I    ++D G+YLC A + + ++++  DLQV  P
Sbjct: 3765 NGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVP 3803



 Score = 30.8 bits (68), Expect = 4.9
 Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 1/58 (1%)

Query: 426  VILNQLTSRDAGFYWCLTNGDTLWRT-TVEIKIIEGEPNLKVPGNVTAVLGETLKVPC 482
            +IL  +   D+GFY C+ N      T TV + +       ++PG+V+   GE L++ C
Sbjct: 4224 LILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSC 4281



 Score = 30.4 bits (67), Expect = 6.4
 Identities = 34/154 (22%), Positives = 62/154 (40%), Gaps = 22/154 (14%)

Query: 90   NGTFVVNIAQLSQDDSGRYKCGLGINSRGLSFDV-SLEVSQGPGLL--NDTKVYTVDLGR 146
            N   ++ + + + +D+GRY C   IN  G S    +++V   P ++  N     +V L R
Sbjct: 1411 NNGKILKLFRATPEDAGRYSCK-AINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNR 1469

Query: 147  TVTINCPFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQGTGQLLFSVV 206
             V + C  K                +P +     G   P + G   +++   GQ+L    
Sbjct: 1470 DVALECQVKGTP-------------FPDIHWFKDG--KPLFLGDPNVELLDRGQVLH--- 1511

Query: 207  INQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKP 240
            +   R +D G+Y C   + +    K+  L +  P
Sbjct: 1512 LKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIP 1545


>gi|7657359 contactin 5 isoform long [Homo sapiens]
          Length = 1100

 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 80/327 (24%), Positives = 122/327 (37%), Gaps = 54/327 (16%)

Query: 65  ITLISSEGYVSSKYAGRANLTNFPENGTFVVNIAQLSQDDSGRYKCGLGINSRGL-SFDV 123
           IT +   GY+ SK   R +          V+ I  +  DD+G Y+C    NSRG  SF  
Sbjct: 332 ITWMKVNGYIPSKARLRKSQA--------VLEIPNVQLDDAGIYEC-RAENSRGKNSFRG 382

Query: 124 SLEVSQGP---GLLNDTKVYTVDLGRTVTINCPFKTENAQKRKSLYKQIGLYPVLVIDSS 180
            L+V   P     LNDT+   +D G  +   C    +     + L   + L P   ++  
Sbjct: 383 QLQVYTYPHWVEKLNDTQ---LDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMV 439

Query: 181 GYVNPNYTGRIRLDIQGTGQLLFSVVINQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKP 240
             V                     ++I+ +  SDAG Y C A +   +   +A+L++L  
Sbjct: 440 NGV---------------------LMIHNVNQSDAGMYQCLAENKYGAIYASAELKILAS 478

Query: 241 EPELVYEDLRGSVTFHCALGPEVANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLN 300
            P      L+ ++        EV    K       G     +    G RA     RI + 
Sbjct: 479 APTFALNQLKKTII--VTKDQEVVIECK-----PQGSPKPTISWKKGDRAVRENKRIAIL 531

Query: 301 PQDKDGSFSVVITGLRKEDAGRYLCGAHSDGQLQEGSPIQAWQLFVNEESTIPRSPTVVK 360
           P   DGS  ++     K D G+Y+C     G+   GS      L V E + I  +P   +
Sbjct: 532 P---DGSLRIL--NASKSDEGKYVC----RGENVFGSAEIIASLSVKEPTRIELTPKRTE 582

Query: 361 GVAGGSVAVLCPYNRKESKSIK-YWCL 386
              G S+ + C      S  +  YW L
Sbjct: 583 LTVGESIVLNCKAIHDASLDVTFYWTL 609


>gi|28373129 contactin 5 isoform short [Homo sapiens]
          Length = 1026

 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 80/327 (24%), Positives = 122/327 (37%), Gaps = 54/327 (16%)

Query: 65  ITLISSEGYVSSKYAGRANLTNFPENGTFVVNIAQLSQDDSGRYKCGLGINSRGL-SFDV 123
           IT +   GY+ SK   R +          V+ I  +  DD+G Y+C    NSRG  SF  
Sbjct: 258 ITWMKVNGYIPSKARLRKSQA--------VLEIPNVQLDDAGIYEC-RAENSRGKNSFRG 308

Query: 124 SLEVSQGP---GLLNDTKVYTVDLGRTVTINCPFKTENAQKRKSLYKQIGLYPVLVIDSS 180
            L+V   P     LNDT+   +D G  +   C    +     + L   + L P   ++  
Sbjct: 309 QLQVYTYPHWVEKLNDTQ---LDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMV 365

Query: 181 GYVNPNYTGRIRLDIQGTGQLLFSVVINQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKP 240
             V                     ++I+ +  SDAG Y C A +   +   +A+L++L  
Sbjct: 366 NGV---------------------LMIHNVNQSDAGMYQCLAENKYGAIYASAELKILAS 404

Query: 241 EPELVYEDLRGSVTFHCALGPEVANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLN 300
            P      L+ ++        EV    K       G     +    G RA     RI + 
Sbjct: 405 APTFALNQLKKTII--VTKDQEVVIECK-----PQGSPKPTISWKKGDRAVRENKRIAIL 457

Query: 301 PQDKDGSFSVVITGLRKEDAGRYLCGAHSDGQLQEGSPIQAWQLFVNEESTIPRSPTVVK 360
           P   DGS  ++     K D G+Y+C     G+   GS      L V E + I  +P   +
Sbjct: 458 P---DGSLRIL--NASKSDEGKYVC----RGENVFGSAEIIASLSVKEPTRIELTPKRTE 508

Query: 361 GVAGGSVAVLCPYNRKESKSIK-YWCL 386
              G S+ + C      S  +  YW L
Sbjct: 509 LTVGESIVLNCKAIHDASLDVTFYWTL 535


>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 3874

 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 41/156 (26%), Positives = 62/156 (39%), Gaps = 20/156 (12%)

Query: 85   TNFPENGTFVVNIAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGPGLLNDTKVYTVDL 144
            T FPE G F+  +  LS  DSG Y C     +   S    +E+   P + +      V +
Sbjct: 2437 TQFPERGRFL-QLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSV 2495

Query: 145  GRTVTINCPFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQGTGQLLFS 204
             +T  + C               Q    P  ++       P      R +I   G L   
Sbjct: 2496 NQTALLPC---------------QADGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQ 2540

Query: 205  VVINQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKP 240
             V+ Q    DAG YLC A + + S+++  DL+VL+P
Sbjct: 2541 PVLAQ----DAGHYLCLASNSAGSDRQGRDLRVLEP 2572



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 70/307 (22%), Positives = 121/307 (39%), Gaps = 52/307 (16%)

Query: 185 PNYTGRIRLDIQGTGQLLFSVVINQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKPEPEL 244
           P   G   L +Q  GQ+L    I    + D G+Y C A   +    ++  L+V  P P +
Sbjct: 257 PVLPGGPHLQVQEDGQVLR---ITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAP-PTI 312

Query: 245 VYEDLRGSVTFHCALGPEVANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLNPQDK 304
              +  G V           ++ + LC        ++     G   P     +       
Sbjct: 313 WGSNETGEVAVM------EDHLVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTR---- 362

Query: 305 DGSFSVVITGLRKEDAGRYLCGAHSDGQLQEGSPIQAWQLFVNEESTIPRS---PTVVKG 361
            G   + +   +  DAG Y C A +      G+  +A +L V    TI  +   P VVK 
Sbjct: 363 -GGRQLQLGRAQSSDAGVYTCKASN----AVGAAEKATRLDVYVPPTIEGAGGRPYVVKA 417

Query: 362 VAGGSVAVLCPYNRKESKSIKYWCLWEGAQNGRCPLLVDSEGWVKAQYEGRLSLLEEPGN 421
           VAG  VA+ C      S ++ +        +   P+   +E   + + +G +  LE PG 
Sbjct: 418 VAGRPVALECVARGHPSPTLSW-------HHEGLPVAESNES--RLETDGSVLRLESPGE 468

Query: 422 GTFTVILNQLTSRDAGFYWCLTN---GDTLWRTTVEIKIIEGEPNLKVP---GNVTAVLG 475
            +            +G Y C+ +   G+ + + +VE+++    P L V    G VT ++G
Sbjct: 469 AS------------SGLYSCVASSPAGEAVLQYSVEVQV---PPQLLVAEGLGQVTTIVG 513

Query: 476 ETLKVPC 482
           + L++PC
Sbjct: 514 QPLELPC 520



 Score = 38.5 bits (88), Expect = 0.024
 Identities = 87/404 (21%), Positives = 145/404 (35%), Gaps = 74/404 (18%)

Query: 123  VSLEVSQGPGLLNDTKVYTVDLGRTVTINCPFKTENAQKRKSLYKQIGLYPVLVIDSSGY 182
            +S  + QGP L    ++  V  G + T +C   +E  + R+    Q+ +     I+ SG 
Sbjct: 2257 LSQSLEQGPSL----QLEAVGAGDSGTYSCVAVSEAGEARRHF--QLTVMEPPHIEDSGQ 2310

Query: 183  -----VNPNYTGRIRLDIQGT----------GQLLFSVVINQ-----LRLSDAGQYLCQA 222
                 + P     +  D QGT          GQ L  +  N      LR+ DAG Y C A
Sbjct: 2311 PTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTRLENNSRATRVLRVRDAGLYTCLA 2370

Query: 223  GDDSNSNKKNADLQVLKPEPELVYEDLRGSVTFHCALGPEVANVAKFLCRQSSGENCDVV 282
               + + +K+  ++V  P P +V              GP        L        C V 
Sbjct: 2371 ESPAGAIEKSFRVRVQAP-PNIV--------------GPRGPRFVVGLAPGQLVLECSVE 2415

Query: 283  VNTLGKRAPAFEGRIL---LNPQDKDGSFSVVITGLRKEDAGRYLCGAHSDGQLQEGSPI 339
                 K     +G +L    + Q  +    + +  L   D+G Y C A +      GS  
Sbjct: 2416 AEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARN----AAGSTS 2471

Query: 340  QAWQLFVNEESTIPRSPTVVKGVAGGSVAVLCPYNRKESKSIKYWCLWEGAQNGRCPLLV 399
             A+++ ++   TI   P  V      +  + C  +   +  + +       +  R PL  
Sbjct: 2472 VAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSW-------RKDRVPLDP 2524

Query: 400  DSEGWVKAQYEGRLSLLEEPGNGTFTVILNQLTSRDAGFYWCL-TNGDTLWRTTVEIKII 458
             S          R  +L E      ++ +  + ++DAG Y CL +N     R   +++++
Sbjct: 2525 RSP---------RFEILPEG-----SLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVL 2570

Query: 459  EGEPNLKVPGNVTAVLGETLKVPCHFPCKFSSYEKYWCKWNNTG 502
            E       P N+T     T   P   PC+ S   K    W   G
Sbjct: 2571 EPPAIAPSPSNLTL----TAHTPALLPCEASGSPKPLVVWWKDG 2610



 Score = 37.4 bits (85), Expect = 0.053
 Identities = 90/393 (22%), Positives = 151/393 (38%), Gaps = 69/393 (17%)

Query: 95   VNIAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGPGLLNDTKVYTVDLGRTVTINC-- 152
            + IA  S +D+G Y C +  NS G +   +  V Q P ++ +      DL  T   +   
Sbjct: 2811 LRIAHASPEDAGNYLC-IAKNSAGSAMGKTRLVVQVPPVIENG---LPDLSTTEGSHAFL 2866

Query: 153  PFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQGTGQLLFSVVINQLRL 212
            P K   + +           P +  D  G       G+    IQ +G+LL    +  L  
Sbjct: 2867 PCKARGSPE-----------PNITWDKDGQPVSGAEGKFT--IQPSGELL----VKNLEG 2909

Query: 213  SDAGQYLCQAGDDSNSNKKNADLQVLKPEPELVYEDLRGSVTFHCALGPEVANVAKFLCR 272
             DAG Y C A +     ++   L +L      V+  L G  +    LG  +     +L  
Sbjct: 2910 QDAGTYTCTAENAVGRARRRVHLTILVLP---VFTTLPGDRSLR--LGDRL-----WLRC 2959

Query: 273  QSSGENCDVVVNTLGKRAPAFEGRILLNPQDKDGSFSVVITGLRKEDAGRYLCGAHSD-G 331
             + G     +  T+  R P  EG       ++DG  ++    + +ED+G Y+C A +  G
Sbjct: 2960 AARGSPTPRIGWTVNDR-PVTEG-----VSEQDGGSTLQRAAVSREDSGTYVCWAENRVG 3013

Query: 332  QLQEGSPIQAWQLFVNEESTIPRSPTVVKGVAGGSVAVLCPYNRKESKSIKYWCLWEGAQ 391
            + Q  S +   +  V +         +V+ V G               SI+  C+  G  
Sbjct: 3014 RTQAVSFVHVKEAPVLQGEAF---SYLVEPVGG---------------SIQLDCVVRGDP 3055

Query: 392  NGRCPLLVDSEGWVKAQYEGRLS-LLEEPGNGTFTVILNQLTSRDAGFYWCLTNGDTLWR 450
                   V    W+K     R S L  +  NG+ T+  ++    DAG Y CL   +    
Sbjct: 3056 -------VPDIHWIKDGLPLRGSHLRHQLQNGSLTI--HRTERDDAGRYQCLAENEMGVA 3106

Query: 451  TTVEIKIIEGEPNLKV-PGNVTAVLGETLKVPC 482
              V I +++  P  +V P ++T   G+ + + C
Sbjct: 3107 KKVVILVLQSAPVFQVEPQDMTVRSGDDVALRC 3139



 Score = 35.4 bits (80), Expect = 0.20
 Identities = 58/239 (24%), Positives = 93/239 (38%), Gaps = 34/239 (14%)

Query: 91   GTFVVNIAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGPGLLNDT--KVYTVDLGRTV 148
            G +++ + Q  + DSG Y C     +     + S+EV   P + N+   +V  V  G+T 
Sbjct: 1213 GGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTA 1272

Query: 149  TINCPFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQGTGQLLFSVVIN 208
             + C   T + Q + + +K       L    + +++P+            G LL    + 
Sbjct: 1273 HLMCNV-TGHPQPKLTWFKD---GRPLARGDAHHISPD------------GVLL---QVL 1313

Query: 209  QLRLSDAGQYLCQAGDDSNSNKKNADLQVLKPEPEL--VYEDLRGSVTFHCALGPEVANV 266
            Q  LS AG Y C A +      K+  L VL     L    +     VT        V N 
Sbjct: 1314 QANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTV------TVNNP 1367

Query: 267  AKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLNPQDKDGSFSVVITGLRKEDAGRYLC 325
               +C   +  + ++   T  K    FE     N Q   G+  + I   +KEDAG+Y C
Sbjct: 1368 ISLICEALAFPSPNI---TWMKDGAPFEAS--RNIQLLPGTHGLQILNAQKEDAGQYTC 1421



 Score = 35.0 bits (79), Expect = 0.26
 Identities = 96/416 (23%), Positives = 152/416 (36%), Gaps = 77/416 (18%)

Query: 147  TVTINCPFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTG-RIRLDIQGTGQLLFSV 205
            T+T+  P   EN  K +++ +  G   VL  D SG   P  T  + R+ ++ +   +  V
Sbjct: 1926 TLTVQVPPTFENP-KTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSA--VHGV 1982

Query: 206  V-------INQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKPEPELVYEDLRGSVT---F 255
            V       +++L+ + AG Y C A +     +K+  + VL      V   +R S      
Sbjct: 1983 VSRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVL------VAPRIRSSGVAREH 2036

Query: 256  HCALGPEVANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLNPQDKDGSFSVVITGL 315
            H   G EV    +  C        DV     G       G  L    D     S+V+ GL
Sbjct: 2037 HVLEGQEV----RLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGG---SLVLKGL 2089

Query: 316  RKEDAGRYLCGAHSDGQLQEGSPIQAWQLFVNEESTIPRSPTVVKGVAGGSVAVLCPYNR 375
            R  DAG Y C AH+     E + +    + V         PT+ +G  G    V  P   
Sbjct: 2090 RASDAGAYTCVAHNPA--GEDARLHTVNVLV--------PPTIKQGADGSGTLVSRP--- 2136

Query: 376  KESKSIKYWCLWEGAQNGRCPLLVDSEGWVKAQYEGRLSLLEEPGNGTFTVILNQLTSRD 435
               + +   C   G+     P+ V    W+K      LS          T+ ++++   D
Sbjct: 2137 --GELVTMVCPVRGSP----PIHV---SWLKDGLPLPLSQRTLLHGSGHTLRISKVQLAD 2187

Query: 436  AGFYWCLT---NGDTLWRTTVEIKIIEGEPNLKVPGNVTAVLGETLKVPCH---FPCKFS 489
            AG + C+     G      T+++++      ++   +V  V G  +++PC     P    
Sbjct: 2188 AGIFTCVAASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLV 2247

Query: 490  SYEKYWCKWNNTGCQAL-PSQDEGPSKAFVNCDENSRLVSLTLNLVTRADEGWYWC 544
            S       W   G   L  S ++GP              SL L  V   D G Y C
Sbjct: 2248 S-------WMKDGEPLLSQSLEQGP--------------SLQLEAVGAGDSGTYSC 2282



 Score = 33.5 bits (75), Expect = 0.76
 Identities = 45/179 (25%), Positives = 68/179 (37%), Gaps = 17/179 (9%)

Query: 207 INQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKPEPELVYEDLRGSVTFHCALGPEVANV 266
           I Q +LSDAG Y C A + + S +    L+V  P    +   L G V         V   
Sbjct: 752 IEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVL--------VNTP 803

Query: 267 AKFLCRQSSGENCDVVVNTLGKR-APAFEGRILLNPQDKDGSFSVVITGLRKEDAGRYLC 325
            +  C  +   +  ++    G   +PA    + + P    G   + +   R  D+GRY C
Sbjct: 804 VRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFP----GGRVLTLASARASDSGRYSC 859

Query: 326 GAHSDGQLQEGSPIQAWQLFVNEESTIPRSPTVVKGVAGGSVAVLCPYNRKESKSIKYW 384
            A S      G   Q   L V+   +I      V  VA  SVA+ C  +      + +W
Sbjct: 860 VAVS----AVGEDRQDVVLQVHMPPSILGEELNVSVVANESVALECQSHAMPPPVLSWW 914



 Score = 33.1 bits (74), Expect = 0.99
 Identities = 32/110 (29%), Positives = 46/110 (41%), Gaps = 6/110 (5%)

Query: 44  PTSVNRHTRKYWCRQGARGGCITLISSEGYVSSKYAGRANLTNFPENGTFVVNIAQLSQD 103
           P  VN   R      GA    +  +     VS   AG   L  FP  G  V+ +A     
Sbjct: 797 PVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSP--AGTPGLQVFP--GGRVLTLASARAS 852

Query: 104 DSGRYKCGLGINSRGLS-FDVSLEVSQGPGLLNDTKVYTVDLGRTVTINC 152
           DSGRY C + +++ G    DV L+V   P +L +    +V    +V + C
Sbjct: 853 DSGRYSC-VAVSAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVALEC 901



 Score = 33.1 bits (74), Expect = 0.99
 Identities = 43/177 (24%), Positives = 68/177 (38%), Gaps = 29/177 (16%)

Query: 91   GTFVVNIAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGPGLLNDTKVY----TVDLGR 146
            G  V+ I  +  +++GRY C              L V   P +L DT+      TV+   
Sbjct: 1611 GGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASS 1670

Query: 147  TVTINCPFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQGTGQLLFSVV 206
            TV++ CP           L   +   P          +P      RL +   GQ+L    
Sbjct: 1671 TVSLQCPALGNPVPTISWLQNGLPFSP----------SP------RLQVLEDGQVL---Q 1711

Query: 207  INQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKP------EPELVYEDLRGSVTFHC 257
            ++   ++DA  Y+C A + + S +K   L+V  P      + E V   L  SV+  C
Sbjct: 1712 VSTAEVADAASYMCVAENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPC 1768



 Score = 31.6 bits (70), Expect = 2.9
 Identities = 39/162 (24%), Positives = 62/162 (38%), Gaps = 21/162 (12%)

Query: 174  VLVIDSSGYVNPNYTGRIRLDIQGTGQLLFSVVINQLRLS-----DAGQYLCQAGDDSNS 228
            +L  ++SG   P  T +       TG     +   QLR++     DAG YLC A + + S
Sbjct: 2775 LLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGS 2834

Query: 229  NKKNADLQV-LKPEPELVYEDLRGSVTFHCALGPEVANVAKFLCRQSSGENCDVVVNTLG 287
                  L V + P  E    DL  +   H  L           C+       ++  +  G
Sbjct: 2835 AMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLP----------CKARGSPEPNITWDKDG 2884

Query: 288  KRAPAFEGRILLNPQDKDGSFSVVITGLRKEDAGRYLCGAHS 329
            +     EG+  + P     S  +++  L  +DAG Y C A +
Sbjct: 2885 QPVSGAEGKFTIQP-----SGELLVKNLEGQDAGTYTCTAEN 2921



 Score = 30.0 bits (66), Expect = 8.4
 Identities = 20/72 (27%), Positives = 33/72 (45%), Gaps = 6/72 (8%)

Query: 175  LVIDSSGYVNPNYTGRIRLDIQGTGQLLF------SVVINQLRLSDAGQYLCQAGDDSNS 228
            L  D   + NP  T          G+ +F      ++ + + RLSD+G Y C+A + +  
Sbjct: 1766 LPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEALNAAGR 1825

Query: 229  NKKNADLQVLKP 240
            ++K   L VL P
Sbjct: 1826 DQKLVQLSVLVP 1837


>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 5065

 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 41/156 (26%), Positives = 62/156 (39%), Gaps = 20/156 (12%)

Query: 85   TNFPENGTFVVNIAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGPGLLNDTKVYTVDL 144
            T FPE G F+  +  LS  DSG Y C     +   S    +E+   P + +      V +
Sbjct: 3628 TQFPERGRFL-QLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSV 3686

Query: 145  GRTVTINCPFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQGTGQLLFS 204
             +T  + C               Q    P  ++       P      R +I   G L   
Sbjct: 3687 NQTALLPC---------------QADGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQ 3731

Query: 205  VVINQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKP 240
             V+ Q    DAG YLC A + + S+++  DL+VL+P
Sbjct: 3732 PVLAQ----DAGHYLCLASNSAGSDRQGRDLRVLEP 3763



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 70/307 (22%), Positives = 121/307 (39%), Gaps = 52/307 (16%)

Query: 185  PNYTGRIRLDIQGTGQLLFSVVINQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKPEPEL 244
            P   G   L +Q  GQ+L    I    + D G+Y C A   +    ++  L+V  P P +
Sbjct: 1448 PVLPGGPHLQVQEDGQVLR---ITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAP-PTI 1503

Query: 245  VYEDLRGSVTFHCALGPEVANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLNPQDK 304
               +  G V           ++ + LC        ++     G   P     +       
Sbjct: 1504 WGSNETGEVAVM------EDHLVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTR---- 1553

Query: 305  DGSFSVVITGLRKEDAGRYLCGAHSDGQLQEGSPIQAWQLFVNEESTIPRS---PTVVKG 361
             G   + +   +  DAG Y C A +      G+  +A +L V    TI  +   P VVK 
Sbjct: 1554 -GGRQLQLGRAQSSDAGVYTCKASN----AVGAAEKATRLDVYVPPTIEGAGGRPYVVKA 1608

Query: 362  VAGGSVAVLCPYNRKESKSIKYWCLWEGAQNGRCPLLVDSEGWVKAQYEGRLSLLEEPGN 421
            VAG  VA+ C      S ++ +        +   P+   +E   + + +G +  LE PG 
Sbjct: 1609 VAGRPVALECVARGHPSPTLSW-------HHEGLPVAESNES--RLETDGSVLRLESPGE 1659

Query: 422  GTFTVILNQLTSRDAGFYWCLTN---GDTLWRTTVEIKIIEGEPNLKVP---GNVTAVLG 475
             +            +G Y C+ +   G+ + + +VE+++    P L V    G VT ++G
Sbjct: 1660 AS------------SGLYSCVASSPAGEAVLQYSVEVQV---PPQLLVAEGLGQVTTIVG 1704

Query: 476  ETLKVPC 482
            + L++PC
Sbjct: 1705 QPLELPC 1711



 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 86/402 (21%), Positives = 153/402 (38%), Gaps = 71/402 (17%)

Query: 86  NFPENGTFVVNIAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGPGLLNDTKVYTVDLG 145
           +F E+G     I + S+ + G Y+C     +        + V+  P  L      TV  G
Sbjct: 472 HFQESGNSSWEILRASKAEEGTYECTAVSRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPG 531

Query: 146 RTVTINCPFKTENAQKRKSLYKQIGLYPV-LVIDSSGYVNPNYTGRIRLDIQGTGQLL-F 203
            T  ++C              + +G  P  L       V P  TGR+        QL   
Sbjct: 532 ETAVLSC--------------RVLGEAPYNLTWVRDWRVLPASTGRV-------AQLADL 570

Query: 204 SVVINQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKPEPELVYEDLRGSVTFHCALGPEV 263
           S+ I+ +  +D G+Y C A + +   + +  L V +     ++   +     H + G EV
Sbjct: 571 SLEISGIIPTDGGRYQCVASNANGVTRASVWLLVREAPQVSIHTSSQ-----HFSQGVEV 625

Query: 264 ANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLNPQDKDGSFSVVITGLRKEDAGRY 323
               K  C  +SG     +  +   +A   + RI ++ Q      +++I G+  EDAG Y
Sbjct: 626 ----KVSC-SASGYPTPHISWSRESQALQEDSRIHVDAQG-----TLIIQGVAPEDAGNY 675

Query: 324 LCGAHSDGQLQEGSPIQAWQLFVNEESTIPRSPTVVKGVAGGSVAVLCPYNRKESKSIKY 383
            C A +    + G+  +   L+  +  ++     VV    G    ++C  +      +  
Sbjct: 676 SCQATN----EVGTDQETVTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRV-- 729

Query: 384 WCLWEGAQNGRCPLLVDSEGWVKAQYEGRLSLLEEP-GNGTFTVILNQLTSRDAGFYWCL 442
             +W                     Y G L ++  P G+ +  + +     RDAG Y C 
Sbjct: 730 --IW---------------------YRGGLEMILAPEGSSSGKLRIPAAQERDAGTYTCR 766

Query: 443 TNGDTLWRTTVEIKIIEGE-PNL-KVPGNVTAVLGETLKVPC 482
              + L   + EI++  G  P L ++P +VT  LG +  + C
Sbjct: 767 AVNE-LGDASAEIQLAVGHAPQLTELPRDVTVELGRSALLAC 807



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 102/462 (22%), Positives = 162/462 (35%), Gaps = 77/462 (16%)

Query: 95   VNIAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGPGLLNDTKVYTVDLGRTVTINCPF 154
            + +AQ+   DSG Y+C     +   S    L V   P +    +V  V +G  + +NC  
Sbjct: 1084 LRLAQVQVGDSGHYECTASNPAGSASHRYVLGVQVPPQVQPGPRVLKVLVGEALDLNCVA 1143

Query: 155  KTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQGTGQLLFSVVINQLRLSD 214
            +                 P L     G V           +QG G    SV    +R SD
Sbjct: 1144 EGNPE-------------PQLSWSKDGVV-----------LQGRGPQ-GSVHFAAIRTSD 1178

Query: 215  AGQYLCQAGDDSNSNKKNADLQVLKPEPELVYEDLRGSVTFHCALGPEVANVAKFLCRQS 274
            AG+Y C+A + +  +    +L+VL+P P    ++  G                  L  + 
Sbjct: 1179 AGRYRCEASNSAGVDAWEVELRVLEP-PHWGADETSG------------------LLERV 1219

Query: 275  SGENCDVVVNTLGKRAPAFEGRILLNPQDKDG--------SFSVVITGLRKEDAGRYLCG 326
            +GEN  +     G   P    R   + +   G          S+ +  +   D+G Y C 
Sbjct: 1220 AGENASLPCPARGTPKPQVTWRKGPSSEPLHGQPGVAVLEEGSLFLASVSPADSGDYECQ 1279

Query: 327  AHSDGQLQEGSPIQAWQLFVNEESTIPRS--PTVVKGVAGGSVAVLCPYNRKESKSIKYW 384
            A +    + GS  +  +L V    +I        V G+AG S+ + C  N      I   
Sbjct: 1280 ATN----EVGSTSRRAKLVVYVPPSIREDGRKANVSGMAGQSLTLECDANGFPVPEI--- 1332

Query: 385  CLW-EGAQNGRCPLLVDSEGWVKAQYE-GRLSLLEEPGNGTFTVILNQLTSRDAGFYWCL 442
             +W + AQ    PL     GW     + G   LL+E  +  F     ++   D+G Y C 
Sbjct: 1333 -VWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFP----RIQEGDSGLYSCR 1387

Query: 443  TNGDTLWRTTVEIKIIEGEPNLKVPGNVTAVLGETLKVPCHFPCKFSSYEKYWCKWNNTG 502
                          ++   P++   G    VLG          C  S       +W    
Sbjct: 1388 AENQAGTAQRDFHLLVLTPPSVLGAGAAQEVLG-LAGADVELQCWTSGVPTPQVEWTKDR 1446

Query: 503  CQALPSQDEGPSKAFVNCDENSRLVSLTLNLVTRADEGWYWC 544
               LP    GP    +   E+ +++ +T + V   DEG Y C
Sbjct: 1447 QPVLPG---GP---HLQVQEDGQVLRITGSHV--GDEGRYQC 1480



 Score = 38.5 bits (88), Expect = 0.024
 Identities = 87/404 (21%), Positives = 145/404 (35%), Gaps = 74/404 (18%)

Query: 123  VSLEVSQGPGLLNDTKVYTVDLGRTVTINCPFKTENAQKRKSLYKQIGLYPVLVIDSSGY 182
            +S  + QGP L    ++  V  G + T +C   +E  + R+    Q+ +     I+ SG 
Sbjct: 3448 LSQSLEQGPSL----QLEAVGAGDSGTYSCVAVSEAGEARRHF--QLTVMEPPHIEDSGQ 3501

Query: 183  -----VNPNYTGRIRLDIQGT----------GQLLFSVVINQ-----LRLSDAGQYLCQA 222
                 + P     +  D QGT          GQ L  +  N      LR+ DAG Y C A
Sbjct: 3502 PTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTRLENNSRATRVLRVRDAGLYTCLA 3561

Query: 223  GDDSNSNKKNADLQVLKPEPELVYEDLRGSVTFHCALGPEVANVAKFLCRQSSGENCDVV 282
               + + +K+  ++V  P P +V              GP        L        C V 
Sbjct: 3562 ESPAGAIEKSFRVRVQAP-PNIV--------------GPRGPRFVVGLAPGQLVLECSVE 3606

Query: 283  VNTLGKRAPAFEGRIL---LNPQDKDGSFSVVITGLRKEDAGRYLCGAHSDGQLQEGSPI 339
                 K     +G +L    + Q  +    + +  L   D+G Y C A +      GS  
Sbjct: 3607 AEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARN----AAGSTS 3662

Query: 340  QAWQLFVNEESTIPRSPTVVKGVAGGSVAVLCPYNRKESKSIKYWCLWEGAQNGRCPLLV 399
             A+++ ++   TI   P  V      +  + C  +   +  + +       +  R PL  
Sbjct: 3663 VAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSW-------RKDRVPLDP 3715

Query: 400  DSEGWVKAQYEGRLSLLEEPGNGTFTVILNQLTSRDAGFYWCL-TNGDTLWRTTVEIKII 458
             S          R  +L E      ++ +  + ++DAG Y CL +N     R   +++++
Sbjct: 3716 RSP---------RFEILPEG-----SLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVL 3761

Query: 459  EGEPNLKVPGNVTAVLGETLKVPCHFPCKFSSYEKYWCKWNNTG 502
            E       P N+T     T   P   PC+ S   K    W   G
Sbjct: 3762 EPPAIAPSPSNLTL----TAHTPALLPCEASGSPKPLVVWWKDG 3801



 Score = 37.4 bits (85), Expect = 0.053
 Identities = 90/393 (22%), Positives = 151/393 (38%), Gaps = 69/393 (17%)

Query: 95   VNIAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGPGLLNDTKVYTVDLGRTVTINC-- 152
            + IA  S +D+G Y C +  NS G +   +  V Q P ++ +      DL  T   +   
Sbjct: 4002 LRIAHASPEDAGNYLC-IAKNSAGSAMGKTRLVVQVPPVIENG---LPDLSTTEGSHAFL 4057

Query: 153  PFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQGTGQLLFSVVINQLRL 212
            P K   + +           P +  D  G       G+    IQ +G+LL    +  L  
Sbjct: 4058 PCKARGSPE-----------PNITWDKDGQPVSGAEGKFT--IQPSGELL----VKNLEG 4100

Query: 213  SDAGQYLCQAGDDSNSNKKNADLQVLKPEPELVYEDLRGSVTFHCALGPEVANVAKFLCR 272
             DAG Y C A +     ++   L +L      V+  L G  +    LG  +     +L  
Sbjct: 4101 QDAGTYTCTAENAVGRARRRVHLTILVLP---VFTTLPGDRSLR--LGDRL-----WLRC 4150

Query: 273  QSSGENCDVVVNTLGKRAPAFEGRILLNPQDKDGSFSVVITGLRKEDAGRYLCGAHSD-G 331
             + G     +  T+  R P  EG       ++DG  ++    + +ED+G Y+C A +  G
Sbjct: 4151 AARGSPTPRIGWTVNDR-PVTEG-----VSEQDGGSTLQRAAVSREDSGTYVCWAENRVG 4204

Query: 332  QLQEGSPIQAWQLFVNEESTIPRSPTVVKGVAGGSVAVLCPYNRKESKSIKYWCLWEGAQ 391
            + Q  S +   +  V +         +V+ V G               SI+  C+  G  
Sbjct: 4205 RTQAVSFVHVKEAPVLQGEAF---SYLVEPVGG---------------SIQLDCVVRGDP 4246

Query: 392  NGRCPLLVDSEGWVKAQYEGRLS-LLEEPGNGTFTVILNQLTSRDAGFYWCLTNGDTLWR 450
                   V    W+K     R S L  +  NG+ T+  ++    DAG Y CL   +    
Sbjct: 4247 -------VPDIHWIKDGLPLRGSHLRHQLQNGSLTI--HRTERDDAGRYQCLAENEMGVA 4297

Query: 451  TTVEIKIIEGEPNLKV-PGNVTAVLGETLKVPC 482
              V I +++  P  +V P ++T   G+ + + C
Sbjct: 4298 KKVVILVLQSAPVFQVEPQDMTVRSGDDVALRC 4330



 Score = 35.4 bits (80), Expect = 0.20
 Identities = 58/239 (24%), Positives = 93/239 (38%), Gaps = 34/239 (14%)

Query: 91   GTFVVNIAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGPGLLNDT--KVYTVDLGRTV 148
            G +++ + Q  + DSG Y C     +     + S+EV   P + N+   +V  V  G+T 
Sbjct: 2404 GGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTA 2463

Query: 149  TINCPFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQGTGQLLFSVVIN 208
             + C   T + Q + + +K       L    + +++P+            G LL    + 
Sbjct: 2464 HLMCNV-TGHPQPKLTWFKD---GRPLARGDAHHISPD------------GVLL---QVL 2504

Query: 209  QLRLSDAGQYLCQAGDDSNSNKKNADLQVLKPEPEL--VYEDLRGSVTFHCALGPEVANV 266
            Q  LS AG Y C A +      K+  L VL     L    +     VT        V N 
Sbjct: 2505 QANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTV------TVNNP 2558

Query: 267  AKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLNPQDKDGSFSVVITGLRKEDAGRYLC 325
               +C   +  + ++   T  K    FE     N Q   G+  + I   +KEDAG+Y C
Sbjct: 2559 ISLICEALAFPSPNI---TWMKDGAPFEAS--RNIQLLPGTHGLQILNAQKEDAGQYTC 2612



 Score = 35.0 bits (79), Expect = 0.26
 Identities = 96/416 (23%), Positives = 152/416 (36%), Gaps = 77/416 (18%)

Query: 147  TVTINCPFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTG-RIRLDIQGTGQLLFSV 205
            T+T+  P   EN  K +++ +  G   VL  D SG   P  T  + R+ ++ +   +  V
Sbjct: 3117 TLTVQVPPTFENP-KTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSA--VHGV 3173

Query: 206  V-------INQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKPEPELVYEDLRGSVT---F 255
            V       +++L+ + AG Y C A +     +K+  + VL      V   +R S      
Sbjct: 3174 VSRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVL------VAPRIRSSGVAREH 3227

Query: 256  HCALGPEVANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLNPQDKDGSFSVVITGL 315
            H   G EV    +  C        DV     G       G  L    D     S+V+ GL
Sbjct: 3228 HVLEGQEV----RLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGG---SLVLKGL 3280

Query: 316  RKEDAGRYLCGAHSDGQLQEGSPIQAWQLFVNEESTIPRSPTVVKGVAGGSVAVLCPYNR 375
            R  DAG Y C AH+     E + +    + V         PT+ +G  G    V  P   
Sbjct: 3281 RASDAGAYTCVAHNPA--GEDARLHTVNVLV--------PPTIKQGADGSGTLVSRP--- 3327

Query: 376  KESKSIKYWCLWEGAQNGRCPLLVDSEGWVKAQYEGRLSLLEEPGNGTFTVILNQLTSRD 435
               + +   C   G+     P+ V    W+K      LS          T+ ++++   D
Sbjct: 3328 --GELVTMVCPVRGSP----PIHV---SWLKDGLPLPLSQRTLLHGSGHTLRISKVQLAD 3378

Query: 436  AGFYWCLT---NGDTLWRTTVEIKIIEGEPNLKVPGNVTAVLGETLKVPCH---FPCKFS 489
            AG + C+     G      T+++++      ++   +V  V G  +++PC     P    
Sbjct: 3379 AGIFTCVAASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLV 3438

Query: 490  SYEKYWCKWNNTGCQAL-PSQDEGPSKAFVNCDENSRLVSLTLNLVTRADEGWYWC 544
            S       W   G   L  S ++GP              SL L  V   D G Y C
Sbjct: 3439 S-------WMKDGEPLLSQSLEQGP--------------SLQLEAVGAGDSGTYSC 3473



 Score = 34.3 bits (77), Expect = 0.45
 Identities = 63/288 (21%), Positives = 115/288 (39%), Gaps = 57/288 (19%)

Query: 204  SVVINQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKPEPELVYEDLRGSVTFHCALGPEV 263
            S+ + Q+++ D+G Y C A + + S      L V  P P++               GP  
Sbjct: 1083 SLRLAQVQVGDSGHYECTASNPAGSASHRYVLGVQVP-PQV-------------QPGP-- 1126

Query: 264  ANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLNPQDKDGSFSVVITGLRKEDAGRY 323
              V K L  ++   NC    N   + + + +G +L   Q +    SV    +R  DAGRY
Sbjct: 1127 -RVLKVLVGEALDLNCVAEGNPEPQLSWSKDGVVL---QGRGPQGSVHFAAIRTSDAGRY 1182

Query: 324  LCGAHSDGQLQEGSPIQAW--QLFVNEESTIPRSPT--VVKGVAGGSVAVLCPYNRKESK 379
             C A         + + AW  +L V E        T  +++ VAG + ++ CP       
Sbjct: 1183 RCEA------SNSAGVDAWEVELRVLEPPHWGADETSGLLERVAGENASLPCP------- 1229

Query: 380  SIKYWCLWEGAQNGRCPLLVDSEGWVKAQYEGR--LSLLEEPGNGTFTVILNQLTSRDAG 437
                      A+    P +   +G       G+  +++LEE      ++ L  ++  D+G
Sbjct: 1230 ----------ARGTPKPQVTWRKGPSSEPLHGQPGVAVLEEG-----SLFLASVSPADSG 1274

Query: 438  FYWCLTNGDTLWRTTVEIKIIEGEPNLKVPG---NVTAVLGETLKVPC 482
             Y C    +    +     ++   P+++  G   NV+ + G++L + C
Sbjct: 1275 DYECQATNEVGSTSRRAKLVVYVPPSIREDGRKANVSGMAGQSLTLEC 1322



 Score = 33.5 bits (75), Expect = 0.76
 Identities = 45/179 (25%), Positives = 68/179 (37%), Gaps = 17/179 (9%)

Query: 207  INQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKPEPELVYEDLRGSVTFHCALGPEVANV 266
            I Q +LSDAG Y C A + + S +    L+V  P    +   L G V         V   
Sbjct: 1943 IEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVL--------VNTP 1994

Query: 267  AKFLCRQSSGENCDVVVNTLGKR-APAFEGRILLNPQDKDGSFSVVITGLRKEDAGRYLC 325
             +  C  +   +  ++    G   +PA    + + P    G   + +   R  D+GRY C
Sbjct: 1995 VRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFP----GGRVLTLASARASDSGRYSC 2050

Query: 326  GAHSDGQLQEGSPIQAWQLFVNEESTIPRSPTVVKGVAGGSVAVLCPYNRKESKSIKYW 384
             A S      G   Q   L V+   +I      V  VA  SVA+ C  +      + +W
Sbjct: 2051 VAVS----AVGEDRQDVVLQVHMPPSILGEELNVSVVANESVALECQSHAMPPPVLSWW 2105



 Score = 33.1 bits (74), Expect = 0.99
 Identities = 32/110 (29%), Positives = 46/110 (41%), Gaps = 6/110 (5%)

Query: 44   PTSVNRHTRKYWCRQGARGGCITLISSEGYVSSKYAGRANLTNFPENGTFVVNIAQLSQD 103
            P  VN   R      GA    +  +     VS   AG   L  FP  G  V+ +A     
Sbjct: 1988 PVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSP--AGTPGLQVFP--GGRVLTLASARAS 2043

Query: 104  DSGRYKCGLGINSRGLS-FDVSLEVSQGPGLLNDTKVYTVDLGRTVTINC 152
            DSGRY C + +++ G    DV L+V   P +L +    +V    +V + C
Sbjct: 2044 DSGRYSC-VAVSAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVALEC 2092



 Score = 33.1 bits (74), Expect = 0.99
 Identities = 43/177 (24%), Positives = 68/177 (38%), Gaps = 29/177 (16%)

Query: 91   GTFVVNIAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGPGLLNDTKVY----TVDLGR 146
            G  V+ I  +  +++GRY C              L V   P +L DT+      TV+   
Sbjct: 2802 GGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASS 2861

Query: 147  TVTINCPFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQGTGQLLFSVV 206
            TV++ CP           L   +   P          +P      RL +   GQ+L    
Sbjct: 2862 TVSLQCPALGNPVPTISWLQNGLPFSP----------SP------RLQVLEDGQVL---Q 2902

Query: 207  INQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKP------EPELVYEDLRGSVTFHC 257
            ++   ++DA  Y+C A + + S +K   L+V  P      + E V   L  SV+  C
Sbjct: 2903 VSTAEVADAASYMCVAENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPC 2959



 Score = 31.6 bits (70), Expect = 2.9
 Identities = 39/162 (24%), Positives = 62/162 (38%), Gaps = 21/162 (12%)

Query: 174  VLVIDSSGYVNPNYTGRIRLDIQGTGQLLFSVVINQLRLS-----DAGQYLCQAGDDSNS 228
            +L  ++SG   P  T +       TG     +   QLR++     DAG YLC A + + S
Sbjct: 3966 LLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGS 4025

Query: 229  NKKNADLQV-LKPEPELVYEDLRGSVTFHCALGPEVANVAKFLCRQSSGENCDVVVNTLG 287
                  L V + P  E    DL  +   H  L           C+       ++  +  G
Sbjct: 4026 AMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLP----------CKARGSPEPNITWDKDG 4075

Query: 288  KRAPAFEGRILLNPQDKDGSFSVVITGLRKEDAGRYLCGAHS 329
            +     EG+  + P     S  +++  L  +DAG Y C A +
Sbjct: 4076 QPVSGAEGKFTIQP-----SGELLVKNLEGQDAGTYTCTAEN 4112



 Score = 31.2 bits (69), Expect = 3.8
 Identities = 25/93 (26%), Positives = 38/93 (40%), Gaps = 19/93 (20%)

Query: 61  RGGCITLISSEGYVSSKYAGRANLTNFPENGTFVVNIAQLSQDDSGRYKCGLGINSRG-L 119
           RGG   +++ EG  S K                 + I    + D+G Y C   +N  G  
Sbjct: 733 RGGLEMILAPEGSSSGK-----------------LRIPAAQERDAGTYTCR-AVNELGDA 774

Query: 120 SFDVSLEVSQGPGLLNDTKVYTVDLGRTVTINC 152
           S ++ L V   P L    +  TV+LGR+  + C
Sbjct: 775 SAEIQLAVGHAPQLTELPRDVTVELGRSALLAC 807



 Score = 30.0 bits (66), Expect = 8.4
 Identities = 20/72 (27%), Positives = 33/72 (45%), Gaps = 6/72 (8%)

Query: 175  LVIDSSGYVNPNYTGRIRLDIQGTGQLLF------SVVINQLRLSDAGQYLCQAGDDSNS 228
            L  D   + NP  T          G+ +F      ++ + + RLSD+G Y C+A + +  
Sbjct: 2957 LPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEALNAAGR 3016

Query: 229  NKKNADLQVLKP 240
            ++K   L VL P
Sbjct: 3017 DQKLVQLSVLVP 3028


>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 3783

 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 41/156 (26%), Positives = 62/156 (39%), Gaps = 20/156 (12%)

Query: 85   TNFPENGTFVVNIAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGPGLLNDTKVYTVDL 144
            T FPE G F+  +  LS  DSG Y C     +   S    +E+   P + +      V +
Sbjct: 2346 TQFPERGRFL-QLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSV 2404

Query: 145  GRTVTINCPFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQGTGQLLFS 204
             +T  + C               Q    P  ++       P      R +I   G L   
Sbjct: 2405 NQTALLPC---------------QADGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQ 2449

Query: 205  VVINQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKP 240
             V+ Q    DAG YLC A + + S+++  DL+VL+P
Sbjct: 2450 PVLAQ----DAGHYLCLASNSAGSDRQGRDLRVLEP 2481



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 70/307 (22%), Positives = 121/307 (39%), Gaps = 52/307 (16%)

Query: 185 PNYTGRIRLDIQGTGQLLFSVVINQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKPEPEL 244
           P   G   L +Q  GQ+L    I    + D G+Y C A   +    ++  L+V  P P +
Sbjct: 166 PVLPGGPHLQVQEDGQVLR---ITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAP-PTI 221

Query: 245 VYEDLRGSVTFHCALGPEVANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLNPQDK 304
              +  G V           ++ + LC        ++     G   P     +       
Sbjct: 222 WGSNETGEVAVM------EDHLVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTR---- 271

Query: 305 DGSFSVVITGLRKEDAGRYLCGAHSDGQLQEGSPIQAWQLFVNEESTIPRS---PTVVKG 361
            G   + +   +  DAG Y C A +      G+  +A +L V    TI  +   P VVK 
Sbjct: 272 -GGRQLQLGRAQSSDAGVYTCKASN----AVGAAEKATRLDVYVPPTIEGAGGRPYVVKA 326

Query: 362 VAGGSVAVLCPYNRKESKSIKYWCLWEGAQNGRCPLLVDSEGWVKAQYEGRLSLLEEPGN 421
           VAG  VA+ C      S ++ +        +   P+   +E   + + +G +  LE PG 
Sbjct: 327 VAGRPVALECVARGHPSPTLSW-------HHEGLPVAESNES--RLETDGSVLRLESPGE 377

Query: 422 GTFTVILNQLTSRDAGFYWCLTN---GDTLWRTTVEIKIIEGEPNLKVP---GNVTAVLG 475
            +            +G Y C+ +   G+ + + +VE+++    P L V    G VT ++G
Sbjct: 378 AS------------SGLYSCVASSPAGEAVLQYSVEVQV---PPQLLVAEGLGQVTTIVG 422

Query: 476 ETLKVPC 482
           + L++PC
Sbjct: 423 QPLELPC 429



 Score = 38.5 bits (88), Expect = 0.024
 Identities = 87/404 (21%), Positives = 145/404 (35%), Gaps = 74/404 (18%)

Query: 123  VSLEVSQGPGLLNDTKVYTVDLGRTVTINCPFKTENAQKRKSLYKQIGLYPVLVIDSSGY 182
            +S  + QGP L    ++  V  G + T +C   +E  + R+    Q+ +     I+ SG 
Sbjct: 2166 LSQSLEQGPSL----QLEAVGAGDSGTYSCVAVSEAGEARRHF--QLTVMEPPHIEDSGQ 2219

Query: 183  -----VNPNYTGRIRLDIQGT----------GQLLFSVVINQ-----LRLSDAGQYLCQA 222
                 + P     +  D QGT          GQ L  +  N      LR+ DAG Y C A
Sbjct: 2220 PTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTRLENNSRATRVLRVRDAGLYTCLA 2279

Query: 223  GDDSNSNKKNADLQVLKPEPELVYEDLRGSVTFHCALGPEVANVAKFLCRQSSGENCDVV 282
               + + +K+  ++V  P P +V              GP        L        C V 
Sbjct: 2280 ESPAGAIEKSFRVRVQAP-PNIV--------------GPRGPRFVVGLAPGQLVLECSVE 2324

Query: 283  VNTLGKRAPAFEGRIL---LNPQDKDGSFSVVITGLRKEDAGRYLCGAHSDGQLQEGSPI 339
                 K     +G +L    + Q  +    + +  L   D+G Y C A +      GS  
Sbjct: 2325 AEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARN----AAGSTS 2380

Query: 340  QAWQLFVNEESTIPRSPTVVKGVAGGSVAVLCPYNRKESKSIKYWCLWEGAQNGRCPLLV 399
             A+++ ++   TI   P  V      +  + C  +   +  + +       +  R PL  
Sbjct: 2381 VAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSW-------RKDRVPLDP 2433

Query: 400  DSEGWVKAQYEGRLSLLEEPGNGTFTVILNQLTSRDAGFYWCL-TNGDTLWRTTVEIKII 458
             S          R  +L E      ++ +  + ++DAG Y CL +N     R   +++++
Sbjct: 2434 RSP---------RFEILPEG-----SLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVL 2479

Query: 459  EGEPNLKVPGNVTAVLGETLKVPCHFPCKFSSYEKYWCKWNNTG 502
            E       P N+T     T   P   PC+ S   K    W   G
Sbjct: 2480 EPPAIAPSPSNLTL----TAHTPALLPCEASGSPKPLVVWWKDG 2519



 Score = 37.0 bits (84), Expect = 0.069
 Identities = 90/393 (22%), Positives = 150/393 (38%), Gaps = 69/393 (17%)

Query: 95   VNIAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGPGLLNDTKVYTVDLGRTVTINC-- 152
            + IA  S +D+G Y C +  NS G +   +  V Q P ++ +      DL  T   +   
Sbjct: 2720 LRIAHASPEDAGNYLC-IAKNSAGSAMGKTRLVVQVPPVIENG---LPDLSTTEGSHAFL 2775

Query: 153  PFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQGTGQLLFSVVINQLRL 212
            P K   + +           P +  D  G       G+    IQ +G+LL    +  L  
Sbjct: 2776 PCKARGSPE-----------PNITWDKDGQPVSGAEGKFT--IQPSGELL----VKNLEG 2818

Query: 213  SDAGQYLCQAGDDSNSNKKNADLQVLKPEPELVYEDLRGSVTFHCALGPEVANVAKFLCR 272
             DAG Y C A +     ++   L +L      V+  L G  +    LG  +     +L  
Sbjct: 2819 QDAGTYTCTAENAVGRARRRVHLTILVLP---VFTTLPGDRSLR--LGDRL-----WLRC 2868

Query: 273  QSSGENCDVVVNTLGKRAPAFEGRILLNPQDKDGSFSVVITGLRKEDAGRYLCGAHSD-G 331
             + G     +  T+  R P  EG       ++DG  ++    + +ED+G Y+C A +  G
Sbjct: 2869 AARGSPTPRIGWTVNDR-PVTEG-----VSEQDGGSTLQRAAVSREDSGTYVCWAENRVG 2922

Query: 332  QLQEGSPIQAWQLFVNEESTIPRSPTVVKGVAGGSVAVLCPYNRKESKSIKYWCLWEGAQ 391
            + Q  S +   +  V +         +V+ V G               SI+  C+  G  
Sbjct: 2923 RTQAVSFVHVKEAPVLQGEAF---SYLVEPVGG---------------SIQLDCVVRGDP 2964

Query: 392  NGRCPLLVDSEGWVKAQYEGRLS-LLEEPGNGTFTVILNQLTSRDAGFYWCLTNGDTLWR 450
                   V    W+K     R S L  +  NG+ T+   +    DAG Y CL   +    
Sbjct: 2965 -------VPDIHWIKDGLPLRGSHLRHQLQNGSLTI--RRTERDDAGRYQCLAENEMGVA 3015

Query: 451  TTVEIKIIEGEPNLKV-PGNVTAVLGETLKVPC 482
              V I +++  P  +V P ++T   G+ + + C
Sbjct: 3016 KKVVILVLQSAPVFQVEPQDMTVRSGDDVALRC 3048



 Score = 35.4 bits (80), Expect = 0.20
 Identities = 58/239 (24%), Positives = 93/239 (38%), Gaps = 34/239 (14%)

Query: 91   GTFVVNIAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGPGLLNDT--KVYTVDLGRTV 148
            G +++ + Q  + DSG Y C     +     + S+EV   P + N+   +V  V  G+T 
Sbjct: 1122 GGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTA 1181

Query: 149  TINCPFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQGTGQLLFSVVIN 208
             + C   T + Q + + +K       L    + +++P+            G LL    + 
Sbjct: 1182 HLMCNV-TGHPQPKLTWFKD---GRPLARGDAHHISPD------------GVLL---QVL 1222

Query: 209  QLRLSDAGQYLCQAGDDSNSNKKNADLQVLKPEPEL--VYEDLRGSVTFHCALGPEVANV 266
            Q  LS AG Y C A +      K+  L VL     L    +     VT        V N 
Sbjct: 1223 QANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTV------TVNNP 1276

Query: 267  AKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLNPQDKDGSFSVVITGLRKEDAGRYLC 325
               +C   +  + ++   T  K    FE     N Q   G+  + I   +KEDAG+Y C
Sbjct: 1277 ISLICEALAFPSPNI---TWMKDGAPFEAS--RNIQLLPGTHGLQILNAQKEDAGQYTC 1330



 Score = 35.0 bits (79), Expect = 0.26
 Identities = 96/416 (23%), Positives = 152/416 (36%), Gaps = 77/416 (18%)

Query: 147  TVTINCPFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTG-RIRLDIQGTGQLLFSV 205
            T+T+  P   EN  K +++ +  G   VL  D SG   P  T  + R+ ++ +   +  V
Sbjct: 1835 TLTVQVPPTFENP-KTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSA--VHGV 1891

Query: 206  V-------INQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKPEPELVYEDLRGSVT---F 255
            V       +++L+ + AG Y C A +     +K+  + VL      V   +R S      
Sbjct: 1892 VSRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVL------VAPRIRSSGVAREH 1945

Query: 256  HCALGPEVANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLNPQDKDGSFSVVITGL 315
            H   G EV    +  C        DV     G       G  L    D     S+V+ GL
Sbjct: 1946 HVLEGQEV----RLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGG---SLVLKGL 1998

Query: 316  RKEDAGRYLCGAHSDGQLQEGSPIQAWQLFVNEESTIPRSPTVVKGVAGGSVAVLCPYNR 375
            R  DAG Y C AH+     E + +    + V         PT+ +G  G    V  P   
Sbjct: 1999 RASDAGAYTCVAHNPA--GEDARLHTVNVLV--------PPTIKQGADGSGTLVSRP--- 2045

Query: 376  KESKSIKYWCLWEGAQNGRCPLLVDSEGWVKAQYEGRLSLLEEPGNGTFTVILNQLTSRD 435
               + +   C   G+     P+ V    W+K      LS          T+ ++++   D
Sbjct: 2046 --GELVTMVCPVRGSP----PIHV---SWLKDGLPLPLSQRTLLHGSGHTLRISKVQLAD 2096

Query: 436  AGFYWCLT---NGDTLWRTTVEIKIIEGEPNLKVPGNVTAVLGETLKVPCH---FPCKFS 489
            AG + C+     G      T+++++      ++   +V  V G  +++PC     P    
Sbjct: 2097 AGIFTCVAASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLV 2156

Query: 490  SYEKYWCKWNNTGCQAL-PSQDEGPSKAFVNCDENSRLVSLTLNLVTRADEGWYWC 544
            S       W   G   L  S ++GP              SL L  V   D G Y C
Sbjct: 2157 S-------WMKDGEPLLSQSLEQGP--------------SLQLEAVGAGDSGTYSC 2191



 Score = 33.5 bits (75), Expect = 0.76
 Identities = 45/179 (25%), Positives = 68/179 (37%), Gaps = 17/179 (9%)

Query: 207 INQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKPEPELVYEDLRGSVTFHCALGPEVANV 266
           I Q +LSDAG Y C A + + S +    L+V  P    +   L G V         V   
Sbjct: 661 IEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVL--------VNTP 712

Query: 267 AKFLCRQSSGENCDVVVNTLGKR-APAFEGRILLNPQDKDGSFSVVITGLRKEDAGRYLC 325
            +  C  +   +  ++    G   +PA    + + P    G   + +   R  D+GRY C
Sbjct: 713 VRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFP----GGRVLTLASARASDSGRYSC 768

Query: 326 GAHSDGQLQEGSPIQAWQLFVNEESTIPRSPTVVKGVAGGSVAVLCPYNRKESKSIKYW 384
            A S      G   Q   L V+   +I      V  VA  SVA+ C  +      + +W
Sbjct: 769 VAVS----AVGEDRQDVVLQVHMPPSILGEELNVSVVANESVALECQSHAMPPPVLSWW 823



 Score = 33.1 bits (74), Expect = 0.99
 Identities = 32/110 (29%), Positives = 46/110 (41%), Gaps = 6/110 (5%)

Query: 44  PTSVNRHTRKYWCRQGARGGCITLISSEGYVSSKYAGRANLTNFPENGTFVVNIAQLSQD 103
           P  VN   R      GA    +  +     VS   AG   L  FP  G  V+ +A     
Sbjct: 706 PVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSP--AGTPGLQVFP--GGRVLTLASARAS 761

Query: 104 DSGRYKCGLGINSRGLS-FDVSLEVSQGPGLLNDTKVYTVDLGRTVTINC 152
           DSGRY C + +++ G    DV L+V   P +L +    +V    +V + C
Sbjct: 762 DSGRYSC-VAVSAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVALEC 810



 Score = 33.1 bits (74), Expect = 0.99
 Identities = 43/177 (24%), Positives = 68/177 (38%), Gaps = 29/177 (16%)

Query: 91   GTFVVNIAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGPGLLNDTKVY----TVDLGR 146
            G  V+ I  +  +++GRY C              L V   P +L DT+      TV+   
Sbjct: 1520 GGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASS 1579

Query: 147  TVTINCPFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQGTGQLLFSVV 206
            TV++ CP           L   +   P          +P      RL +   GQ+L    
Sbjct: 1580 TVSLQCPALGNPVPTISWLQNGLPFSP----------SP------RLQVLEDGQVL---Q 1620

Query: 207  INQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKP------EPELVYEDLRGSVTFHC 257
            ++   ++DA  Y+C A + + S +K   L+V  P      + E V   L  SV+  C
Sbjct: 1621 VSTAEVADAASYMCVAENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPC 1677



 Score = 31.6 bits (70), Expect = 2.9
 Identities = 39/162 (24%), Positives = 62/162 (38%), Gaps = 21/162 (12%)

Query: 174  VLVIDSSGYVNPNYTGRIRLDIQGTGQLLFSVVINQLRLS-----DAGQYLCQAGDDSNS 228
            +L  ++SG   P  T +       TG     +   QLR++     DAG YLC A + + S
Sbjct: 2684 LLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGS 2743

Query: 229  NKKNADLQV-LKPEPELVYEDLRGSVTFHCALGPEVANVAKFLCRQSSGENCDVVVNTLG 287
                  L V + P  E    DL  +   H  L           C+       ++  +  G
Sbjct: 2744 AMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLP----------CKARGSPEPNITWDKDG 2793

Query: 288  KRAPAFEGRILLNPQDKDGSFSVVITGLRKEDAGRYLCGAHS 329
            +     EG+  + P     S  +++  L  +DAG Y C A +
Sbjct: 2794 QPVSGAEGKFTIQP-----SGELLVKNLEGQDAGTYTCTAEN 2830



 Score = 30.0 bits (66), Expect = 8.4
 Identities = 20/72 (27%), Positives = 33/72 (45%), Gaps = 6/72 (8%)

Query: 175  LVIDSSGYVNPNYTGRIRLDIQGTGQLLF------SVVINQLRLSDAGQYLCQAGDDSNS 228
            L  D   + NP  T          G+ +F      ++ + + RLSD+G Y C+A + +  
Sbjct: 1675 LPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEALNAAGR 1734

Query: 229  NKKNADLQVLKP 240
            ++K   L VL P
Sbjct: 1735 DQKLVQLSVLVP 1746


>gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42
           precursor [Homo sapiens]
          Length = 2012

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 85/405 (20%), Positives = 147/405 (36%), Gaps = 82/405 (20%)

Query: 181 GYVNPNYT---GRIRLDIQGTGQ-LLFSVVINQLRLSDAGQYLCQAGDDSNSNKKNADLQ 236
           G+  P+Y      + L++ G  Q  +  ++I  +R SD+G Y+C+  +   + K    L 
Sbjct: 250 GHPEPDYRWLKDNMPLELSGRFQKTVTGLLIENIRPSDSGSYVCEVSNRYGTAKVIGRLY 309

Query: 237 VLKP-----EPELVYEDLRGSVTFHCALGPEVANVAKFLCRQSSGENCDVVVNTLGKRAP 291
           V +P      P  V   +   V+  C+                       V  T  +   
Sbjct: 310 VKQPLKATISPRKVKSSVGSQVSLSCS-----------------------VTGTEDQELS 346

Query: 292 AFEGRILLNPQDKDGSFSVVITGLR----------KEDAGRYLCGAHSDGQLQEGSPIQA 341
            +    +LNP       +V ITG+           K D G Y C    D +L     +Q 
Sbjct: 347 WYRNGEILNP-----GKNVRITGINHENLIMDHMVKSDGGAYQCFVRKD-KLSAQDYVQV 400

Query: 342 WQLFVNEESTIPRSPTVVKGVAGGSVAVLCPYNRKESKSIKYWCLWEGAQNGRCPLLVDS 401
               V E+ T        K ++  S  V+ P     ++ +   C  +G         +D 
Sbjct: 401 ----VLEDGT-------PKIISAFSEKVVSP-----AEPVSLMCNVKGTPLPTITWTLDD 444

Query: 402 EGWVKAQYEGRLSLLEEPGNGTFTVILNQLTSRDAGFYWCLTN---GDTLWRTTVEIKII 458
           +  +K        ++   GN    + ++    RD G Y C  N   G  L++  + ++  
Sbjct: 445 DPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVR-- 502

Query: 459 EGEPNLKVPGNVTAVLGETLKVPCHFPCKFSSYEKYWCKWNNTGCQALPSQDEGPSKAFV 518
            G  +++   N+TA+ G       +  C+   Y  Y  KW       LP        AF 
Sbjct: 503 -GPASIRPMKNITAIAGR----DTYIHCRVIGYPYYSIKWYKNS-NLLPFNHR--QVAF- 553

Query: 519 NCDENSRLVSLTLNLVTRADEGWYWCGVKQGHFYGETAAVYVAVE 563
              EN+  + L+ ++    DEG Y C V        + +V+V V+
Sbjct: 554 ---ENNGTLKLS-DVQKEVDEGEYTCNVLVQPQLSTSQSVHVTVK 594


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.132    0.392 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,879,050
Number of Sequences: 37866
Number of extensions: 1303637
Number of successful extensions: 4720
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 45
Number of HSP's successfully gapped in prelim test: 148
Number of HSP's that attempted gapping in prelim test: 3576
Number of HSP's gapped (non-prelim): 1118
length of query: 764
length of database: 18,247,518
effective HSP length: 110
effective length of query: 654
effective length of database: 14,082,258
effective search space: 9209796732
effective search space used: 9209796732
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press