Guide to the Human Genome
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Search of human proteins with 31083053

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31083053 ceroid-lipofuscinosis, neuronal 8 [Homo sapiens]
         (286 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31083053 ceroid-lipofuscinosis, neuronal 8 [Homo sapiens]          608   e-174
gi|239756685 PREDICTED: TLC domain containing 2 [Homo sapiens]         45   6e-05
gi|239751182 PREDICTED: hypothetical protein [Homo sapiens]            45   6e-05
gi|239745670 PREDICTED: TLC domain containing 2 [Homo sapiens]         45   6e-05
gi|22749023 transmembrane protein 56 [Homo sapiens]                    44   2e-04
gi|109638743 hypothetical protein LOC83723 [Homo sapiens]              38   0.009
gi|13376162 family with sequence similarity 57, member A [Homo s...    37   0.026
gi|52317146 olfactory receptor, family 51, subfamily A, member 2...    31   1.4  
gi|52693925 olfactory receptor, family 51, subfamily A, member 4...    31   1.4  
gi|42542394 lysophosphatidylcholine acyltransferase 3 [Homo sapi...    30   1.9  
gi|5032143 TBP-associated factor 1A isoform 1 [Homo sapiens]           30   2.4  
gi|21536362 TBP-associated factor 1A isoform 2 [Homo sapiens]          30   2.4  
gi|52317140 olfactory receptor, family 51, subfamily A, member 7...    28   7.1  

>gi|31083053 ceroid-lipofuscinosis, neuronal 8 [Homo sapiens]
          Length = 286

 Score =  608 bits (1567), Expect = e-174
 Identities = 286/286 (100%), Positives = 286/286 (100%)

Query: 1   MNPASDGGTSESIFDLDYASWGIRSTLMVAGFVFYLGVFVVCHQLSSSLNATYRSLVARE 60
           MNPASDGGTSESIFDLDYASWGIRSTLMVAGFVFYLGVFVVCHQLSSSLNATYRSLVARE
Sbjct: 1   MNPASDGGTSESIFDLDYASWGIRSTLMVAGFVFYLGVFVVCHQLSSSLNATYRSLVARE 60

Query: 61  KVFWDLAATRAVFGVQSTAAGLWALLGDPVLHADKARGQQNWCWFHITTATGFFCFENVA 120
           KVFWDLAATRAVFGVQSTAAGLWALLGDPVLHADKARGQQNWCWFHITTATGFFCFENVA
Sbjct: 61  KVFWDLAATRAVFGVQSTAAGLWALLGDPVLHADKARGQQNWCWFHITTATGFFCFENVA 120

Query: 121 VHLSNLIFRTFDLFLVIHHLFAFLGFLGCLVNLQAGHYLAMTTLLLEMSTPFTCVSWMLL 180
           VHLSNLIFRTFDLFLVIHHLFAFLGFLGCLVNLQAGHYLAMTTLLLEMSTPFTCVSWMLL
Sbjct: 121 VHLSNLIFRTFDLFLVIHHLFAFLGFLGCLVNLQAGHYLAMTTLLLEMSTPFTCVSWMLL 180

Query: 181 KAGWSESLFWKLNQWLMIHMFHCRMVLTYHMWWVCFWHWDGLVSSLYLPHLTLFLVGLAL 240
           KAGWSESLFWKLNQWLMIHMFHCRMVLTYHMWWVCFWHWDGLVSSLYLPHLTLFLVGLAL
Sbjct: 181 KAGWSESLFWKLNQWLMIHMFHCRMVLTYHMWWVCFWHWDGLVSSLYLPHLTLFLVGLAL 240

Query: 241 LTLIINPYWTHKKTQQLLNPVDWNFAQPEAKSRPEGNGQLLRKKRP 286
           LTLIINPYWTHKKTQQLLNPVDWNFAQPEAKSRPEGNGQLLRKKRP
Sbjct: 241 LTLIINPYWTHKKTQQLLNPVDWNFAQPEAKSRPEGNGQLLRKKRP 286


>gi|239756685 PREDICTED: TLC domain containing 2 [Homo sapiens]
          Length = 264

 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 37/139 (26%), Positives = 67/139 (48%), Gaps = 16/139 (11%)

Query: 63  FWDLAATRAVFGVQSTAAGLWALLG---DPVLHADKARGQQNWCWFHITTATGFFCFENV 119
           +W+L  + A     S  +G  ALLG    P + AD   G   W    +  + G+F  +  
Sbjct: 39  WWNLCVSLA----HSLLSGTGALLGLSLYPQMAADPIHGHPRWALVLVAVSVGYFLADGA 94

Query: 120 AVHLSNLIFRTFDLFLVIHHLFAFLGFLGCL-VNLQAGHYL--AMTTLLLEMSTPFTCVS 176
            +  +  + +T+D  L+ HHL      + CL   + +GHY+  +M +LLLE+++    + 
Sbjct: 95  DLLWNQTLGKTWD--LLCHHLVV----VSCLSTAVLSGHYVGFSMVSLLLELNSACLHLR 148

Query: 177 WMLLKAGWSESLFWKLNQW 195
            +LL +  + SL + +  W
Sbjct: 149 KLLLLSRQAPSLAFSVTSW 167


>gi|239751182 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 264

 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 37/139 (26%), Positives = 67/139 (48%), Gaps = 16/139 (11%)

Query: 63  FWDLAATRAVFGVQSTAAGLWALLG---DPVLHADKARGQQNWCWFHITTATGFFCFENV 119
           +W+L  + A     S  +G  ALLG    P + AD   G   W    +  + G+F  +  
Sbjct: 39  WWNLCVSLA----HSLLSGTGALLGLSLYPQMAADPIHGHPRWALVLVAVSVGYFLADGA 94

Query: 120 AVHLSNLIFRTFDLFLVIHHLFAFLGFLGCL-VNLQAGHYL--AMTTLLLEMSTPFTCVS 176
            +  +  + +T+D  L+ HHL      + CL   + +GHY+  +M +LLLE+++    + 
Sbjct: 95  DLLWNQTLGKTWD--LLCHHLVV----VSCLSTAVLSGHYVGFSMVSLLLELNSACLHLR 148

Query: 177 WMLLKAGWSESLFWKLNQW 195
            +LL +  + SL + +  W
Sbjct: 149 KLLLLSRQAPSLAFSVTSW 167


>gi|239745670 PREDICTED: TLC domain containing 2 [Homo sapiens]
          Length = 264

 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 37/139 (26%), Positives = 67/139 (48%), Gaps = 16/139 (11%)

Query: 63  FWDLAATRAVFGVQSTAAGLWALLG---DPVLHADKARGQQNWCWFHITTATGFFCFENV 119
           +W+L  + A     S  +G  ALLG    P + AD   G   W    +  + G+F  +  
Sbjct: 39  WWNLCVSLA----HSLLSGTGALLGLSLYPQMAADPIHGHPRWALVLVAVSVGYFLADGA 94

Query: 120 AVHLSNLIFRTFDLFLVIHHLFAFLGFLGCL-VNLQAGHYL--AMTTLLLEMSTPFTCVS 176
            +  +  + +T+D  L+ HHL      + CL   + +GHY+  +M +LLLE+++    + 
Sbjct: 95  DLLWNQTLGKTWD--LLCHHLVV----VSCLSTAVLSGHYVGFSMVSLLLELNSACLHLR 148

Query: 177 WMLLKAGWSESLFWKLNQW 195
            +LL +  + SL + +  W
Sbjct: 149 KLLLLSRQAPSLAFSVTSW 167


>gi|22749023 transmembrane protein 56 [Homo sapiens]
          Length = 263

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 35/153 (22%), Positives = 63/153 (41%), Gaps = 3/153 (1%)

Query: 25  STLMVAGFVFYLGVFVVCHQLSSSLNATYRSLVAREKVFWDLAATRAVFGVQSTAAGLWA 84
           S   ++ F F L  + V +  S+ ++  + SL  ++K+ W+         +     GL+ 
Sbjct: 10  SVTCISFFTFQLLFYFVSYWFSAKVSPGFNSLSFKKKIEWNSRVVSTCHSLVVGIFGLYI 69

Query: 85  LLGDPVLHADKARGQQNWCWFHITTATGFFCFENVAVHLSNLIFRTFDLFLVIHHLFAFL 144
            L D    AD   G  +    +I  A+G+   +   + L   +    D F ++HH  +  
Sbjct: 70  FLFDEATKADPLWGGPSLANVNIAIASGYLISDLSIIILYWKVIG--DKFFIMHHCASLY 127

Query: 145 GFLGCLVNLQAGHYLAMTTLLLEMSTPFTCVSW 177
            +   L N     Y+    LL E+S+PF    W
Sbjct: 128 AYYLVLKNGVLA-YIGNFRLLAELSSPFVNQRW 159


>gi|109638743 hypothetical protein LOC83723 [Homo sapiens]
          Length = 274

 Score = 38.1 bits (87), Expect = 0.009
 Identities = 24/85 (28%), Positives = 43/85 (50%), Gaps = 3/85 (3%)

Query: 132 DLFLVIHHLFAFLGF--LGCLVNLQAGHYLAMTTLLLEMSTPFTCVSWMLLKAGWSESLF 189
           +  +V+HH    L    L  +     G +     L+ E+STPF C+  +L++     +L 
Sbjct: 129 EFLMVLHHAAMVLVCFPLSVVWRQGKGDFFLGCMLMAEVSTPFVCLGKILIQYKQQHTLL 188

Query: 190 WKLNQWLMIHMF-HCRMVLTYHMWW 213
            K+N  LM+  F  CR++L  +++W
Sbjct: 189 HKVNGALMLLSFLCCRVLLFPYLYW 213


>gi|13376162 family with sequence similarity 57, member A [Homo
           sapiens]
          Length = 257

 Score = 36.6 bits (83), Expect = 0.026
 Identities = 49/241 (20%), Positives = 96/241 (39%), Gaps = 28/241 (11%)

Query: 28  MVAGFVFYLGVFVVCHQLSSSLNATYRSLVAREKVFWDLAATRAVFGVQSTAAGLWALLG 87
           +  G +F+ G+F +C   + +L  +       + V        +V  V +T +G+  +  
Sbjct: 5   LAGGALFFPGLFALC---TWALRRSQPGWSRTDCVMISTRLVSSVHAVLATGSGIVIIRS 61

Query: 88  DPVLHADKARGQQNWCWFHITTATGFFCFENVAVHLS------------NLIFRTF---D 132
              +   +    + + WF I     +  +++ A++L             +L  R F   +
Sbjct: 62  CDDVITGRHWLAREYVWFLIP----YMIYDSYAMYLCEWCRTRDQNRAPSLTLRNFLSRN 117

Query: 133 LFLVIHHLFAFLGFLGCLVNLQA--GHYLAMTTLLLEMSTPFTCVSWMLLKAGWSESLFW 190
             ++ HH       +     L+   G +        E+STPF  +  +L++     +L +
Sbjct: 118 RLMITHHAVILFVLVPVAQRLRGDLGDFFVGCIFTAELSTPFVSLGRVLIQLKQQHTLLY 177

Query: 191 KLNQWLMIHMF-HCRMVLTYHMWWVCFWHWDGLVSSLYLPHLTLFLVGLALLTLII-NPY 248
           K+N  L +  F  CR++L   M+W  +    GL S L +P    F   +A   L+    Y
Sbjct: 178 KVNGILTLATFLSCRILLFPFMYW-SYGRQQGL-SLLQVPFSIPFYCNVANAFLVAPQIY 235

Query: 249 W 249
           W
Sbjct: 236 W 236


>gi|52317146 olfactory receptor, family 51, subfamily A, member 2
           [Homo sapiens]
          Length = 313

 Score = 30.8 bits (68), Expect = 1.4
 Identities = 19/64 (29%), Positives = 29/64 (45%)

Query: 110 ATGFFCFENVAVHLSNLIFRTFDLFLVIHHLFAFLGFLGCLVNLQAGHYLAMTTLLLEMS 169
           A  FF      +  S L+  +FD FL IH+   +   L  +   Q G   +  ++LL + 
Sbjct: 101 AQEFFIHGFSVLESSVLLIMSFDRFLAIHNPLRYTSILTTVRVAQIGIVFSFKSMLLVLP 160

Query: 170 TPFT 173
            PFT
Sbjct: 161 FPFT 164


>gi|52693925 olfactory receptor, family 51, subfamily A, member 4
           [Homo sapiens]
          Length = 313

 Score = 30.8 bits (68), Expect = 1.4
 Identities = 19/64 (29%), Positives = 29/64 (45%)

Query: 110 ATGFFCFENVAVHLSNLIFRTFDLFLVIHHLFAFLGFLGCLVNLQAGHYLAMTTLLLEMS 169
           A  FF      +  S L+  +FD FL IH+   +   L  +   Q G   +  ++LL + 
Sbjct: 101 AQEFFIHGFSVLESSVLLIMSFDRFLAIHNPLRYTSILTTVRVAQIGIVFSFKSMLLVLP 160

Query: 170 TPFT 173
            PFT
Sbjct: 161 FPFT 164


>gi|42542394 lysophosphatidylcholine acyltransferase 3 [Homo
           sapiens]
          Length = 487

 Score = 30.4 bits (67), Expect = 1.9
 Identities = 21/60 (35%), Positives = 30/60 (50%), Gaps = 6/60 (10%)

Query: 6   DGGTSESIFDLD---YASWGIRSTLMVAGFVFYLGVFVVCHQLSSSLNATYRSLVAREKV 62
           DGG  ++    +   YA  G+ S L VAGF ++ G F+V  Q S +    Y  LV  E +
Sbjct: 161 DGGKDQNSLSSEQQKYAIRGVPSLLEVAGFSYFYGAFLVGPQFSMN---HYMKLVQGELI 217


>gi|5032143 TBP-associated factor 1A isoform 1 [Homo sapiens]
          Length = 450

 Score = 30.0 bits (66), Expect = 2.4
 Identities = 19/61 (31%), Positives = 25/61 (40%), Gaps = 5/61 (8%)

Query: 140 LFAFLGFLGCLVNLQAGHYLA--MTTLLLEMSTPFTCVSWMLLKAGWSE---SLFWKLNQ 194
           LF  L F GC  N+ A  YLA  +  +L+     +    W   K  W     S FW  + 
Sbjct: 333 LFGVLDFAGCTKNITAWKYLAKYLKNILMGNHLAWVQEEWNSRKNWWPGFHFSYFWAKSD 392

Query: 195 W 195
           W
Sbjct: 393 W 393


>gi|21536362 TBP-associated factor 1A isoform 2 [Homo sapiens]
          Length = 336

 Score = 30.0 bits (66), Expect = 2.4
 Identities = 19/61 (31%), Positives = 25/61 (40%), Gaps = 5/61 (8%)

Query: 140 LFAFLGFLGCLVNLQAGHYLA--MTTLLLEMSTPFTCVSWMLLKAGWSE---SLFWKLNQ 194
           LF  L F GC  N+ A  YLA  +  +L+     +    W   K  W     S FW  + 
Sbjct: 219 LFGVLDFAGCTKNITAWKYLAKYLKNILMGNHLAWVQEEWNSRKNWWPGFHFSYFWAKSD 278

Query: 195 W 195
           W
Sbjct: 279 W 279


>gi|52317140 olfactory receptor, family 51, subfamily A, member 7
           [Homo sapiens]
          Length = 312

 Score = 28.5 bits (62), Expect = 7.1
 Identities = 19/64 (29%), Positives = 29/64 (45%)

Query: 110 ATGFFCFENVAVHLSNLIFRTFDLFLVIHHLFAFLGFLGCLVNLQAGHYLAMTTLLLEMS 169
           A  FF      +  S L+  + D FL IH+   +   L      + G  LA+ ++LL + 
Sbjct: 99  AQEFFIHGFTVMESSVLLIMSLDRFLAIHNPLRYSSILTSNRVAKMGLILAIRSILLVIP 158

Query: 170 TPFT 173
            PFT
Sbjct: 159 FPFT 162


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.329    0.139    0.484 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,639,621
Number of Sequences: 37866
Number of extensions: 424021
Number of successful extensions: 1015
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1003
Number of HSP's gapped (non-prelim): 14
length of query: 286
length of database: 18,247,518
effective HSP length: 101
effective length of query: 185
effective length of database: 14,423,052
effective search space: 2668264620
effective search space used: 2668264620
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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