Guide to the Human Genome
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Search of human proteins with 30520329

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|30520329 lysophosphatidic acid acyltransferase zeta
precursor [Homo sapiens]
         (456 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|30520329 lysophosphatidic acid acyltransferase zeta precursor...   919   0.0  
gi|21362092 1-acylglycerol-3-phosphate O-acyltransferase 9 [Homo...   614   e-176
gi|47086907 lysophosphatidylcholine acyltransferase 2 [Homo sapi...    62   1e-09
gi|33946291 lysophosphatidylcholine acyltransferase 1 [Homo sapi...    60   5e-09
gi|87116681 lysophosphatidylcholine acyltransferase 4 [Homo sapi...    59   7e-09
gi|5453718 1-acylglycerol-3-phosphate O-acyltransferase 1 [Homo ...    34   0.31 
gi|15100175 1-acylglycerol-3-phosphate O-acyltransferase 1 [Homo...    34   0.31 
gi|6041665 1-acylglycerol-3-phosphate O-acyltransferase 2 isofor...    31   2.0  
gi|239735569 grainyhead-like 1 [Homo sapiens]                          30   4.5  
gi|209862760 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, ...    30   5.9  

>gi|30520329 lysophosphatidic acid acyltransferase zeta precursor
           [Homo sapiens]
          Length = 456

 Score =  919 bits (2374), Expect = 0.0
 Identities = 456/456 (100%), Positives = 456/456 (100%)

Query: 1   MFLLLPFDSLIVNLLGISLTVLFTLLLVFIIVPAIFGVSFGIRKLYMKSLLKIFAWATLR 60
           MFLLLPFDSLIVNLLGISLTVLFTLLLVFIIVPAIFGVSFGIRKLYMKSLLKIFAWATLR
Sbjct: 1   MFLLLPFDSLIVNLLGISLTVLFTLLLVFIIVPAIFGVSFGIRKLYMKSLLKIFAWATLR 60

Query: 61  MERGAKEKNHQLYKPYTNGIIAKDPTSLEEEIKEIRRSGSSKALDNTPEFELSDIFYFCR 120
           MERGAKEKNHQLYKPYTNGIIAKDPTSLEEEIKEIRRSGSSKALDNTPEFELSDIFYFCR
Sbjct: 61  MERGAKEKNHQLYKPYTNGIIAKDPTSLEEEIKEIRRSGSSKALDNTPEFELSDIFYFCR 120

Query: 121 KGMETIMDDEVTKRFSAEELESWNLLSRTNYNFQYISLRLTVLWGLGVLIRYCFLLPLRI 180
           KGMETIMDDEVTKRFSAEELESWNLLSRTNYNFQYISLRLTVLWGLGVLIRYCFLLPLRI
Sbjct: 121 KGMETIMDDEVTKRFSAEELESWNLLSRTNYNFQYISLRLTVLWGLGVLIRYCFLLPLRI 180

Query: 181 ALAFTGISLLVVGTTVVGYLPNGRFKEFMSKHVHLMCYRICVRALTAIITYHDRENRPRN 240
           ALAFTGISLLVVGTTVVGYLPNGRFKEFMSKHVHLMCYRICVRALTAIITYHDRENRPRN
Sbjct: 181 ALAFTGISLLVVGTTVVGYLPNGRFKEFMSKHVHLMCYRICVRALTAIITYHDRENRPRN 240

Query: 241 GGICVANHTSPIDVIILASDGYYAMVGQVHGGLMGVIQRAMVKACPHVWFERSEVKDRHL 300
           GGICVANHTSPIDVIILASDGYYAMVGQVHGGLMGVIQRAMVKACPHVWFERSEVKDRHL
Sbjct: 241 GGICVANHTSPIDVIILASDGYYAMVGQVHGGLMGVIQRAMVKACPHVWFERSEVKDRHL 300

Query: 301 VAKRLTEHVQDKSKLPILIFPEGTCINNTSVMMFKKGSFEIGATVYPVAIKYDPQFGDAF 360
           VAKRLTEHVQDKSKLPILIFPEGTCINNTSVMMFKKGSFEIGATVYPVAIKYDPQFGDAF
Sbjct: 301 VAKRLTEHVQDKSKLPILIFPEGTCINNTSVMMFKKGSFEIGATVYPVAIKYDPQFGDAF 360

Query: 361 WNSSKYGMVTYLLRMMTSWAIVCSVWYLPPMTREADEDAVQFANRVKSAIARQGGLVDLL 420
           WNSSKYGMVTYLLRMMTSWAIVCSVWYLPPMTREADEDAVQFANRVKSAIARQGGLVDLL
Sbjct: 361 WNSSKYGMVTYLLRMMTSWAIVCSVWYLPPMTREADEDAVQFANRVKSAIARQGGLVDLL 420

Query: 421 WDGGLKREKVKDTFKEEQQKLYSKMIVGNHKDRSRS 456
           WDGGLKREKVKDTFKEEQQKLYSKMIVGNHKDRSRS
Sbjct: 421 WDGGLKREKVKDTFKEEQQKLYSKMIVGNHKDRSRS 456


>gi|21362092 1-acylglycerol-3-phosphate O-acyltransferase 9 [Homo
           sapiens]
          Length = 434

 Score =  614 bits (1583), Expect = e-176
 Identities = 301/436 (69%), Positives = 356/436 (81%), Gaps = 11/436 (2%)

Query: 14  LLGISLTVLFTLLLVFIIVPAIFGVSFGIRKLYMKSLLKIFAWATLRMERGAKEKNHQLY 73
           L G  L+   TL+L FI++P++FGVS GI ++YMK L+K   WAT+R+E+G   K   L 
Sbjct: 6   LAGKILSTWLTLVLGFILLPSVFGVSLGISEIYMKILVKTLEWATIRIEKGTP-KESILK 64

Query: 74  KPYTNGIIAKDPTSLEEEIKEIRRSGSSKALDNTPEFELSDIFYFCRKGMETIMDDEVTK 133
              + GII +D + +E+ +  +R            +FELSD+FYF +KG+E I++DEVT+
Sbjct: 65  NSASVGIIQRDESPMEKGLSGLRGR----------DFELSDVFYFSKKGLEAIVEDEVTQ 114

Query: 134 RFSAEELESWNLLSRTNYNFQYISLRLTVLWGLGVLIRYCFLLPLRIALAFTGISLLVVG 193
           RFS+EEL SWNLL+RTN NFQYISLRLT++W LGV++RYC LLPLR+ LAF GISLLV+G
Sbjct: 115 RFSSEELVSWNLLTRTNVNFQYISLRLTMVWVLGVIVRYCVLLPLRVTLAFIGISLLVIG 174

Query: 194 TTVVGYLPNGRFKEFMSKHVHLMCYRICVRALTAIITYHDRENRPRNGGICVANHTSPID 253
           TT+VG LP+   K ++S+ VHL C RICVRAL+  I YH+++ RP+ GGICVANHTSPID
Sbjct: 175 TTLVGQLPDSSLKNWLSELVHLTCCRICVRALSGTIHYHNKQYRPQKGGICVANHTSPID 234

Query: 254 VIILASDGYYAMVGQVHGGLMGVIQRAMVKACPHVWFERSEVKDRHLVAKRLTEHVQDKS 313
           V+IL +DG YAMVGQVHGGLMG+IQRAMVKACPHVWFERSE+KDRHLV KRL EH+ DK 
Sbjct: 235 VLILTTDGCYAMVGQVHGGLMGIIQRAMVKACPHVWFERSEMKDRHLVTKRLKEHIADKK 294

Query: 314 KLPILIFPEGTCINNTSVMMFKKGSFEIGATVYPVAIKYDPQFGDAFWNSSKYGMVTYLL 373
           KLPILIFPEGTCINNTSVMMFKKGSFEIG T++PVAIKY+PQFGDAFWNSSKY MV+YLL
Sbjct: 295 KLPILIFPEGTCINNTSVMMFKKGSFEIGGTIHPVAIKYNPQFGDAFWNSSKYNMVSYLL 354

Query: 374 RMMTSWAIVCSVWYLPPMTREADEDAVQFANRVKSAIARQGGLVDLLWDGGLKREKVKDT 433
           RMMTSWAIVC VWY+PPMTRE  EDAVQFANRVKSAIA QGGL +L WDGGLKR KVKD 
Sbjct: 355 RMMTSWAIVCDVWYMPPMTREEGEDAVQFANRVKSAIAIQGGLTELPWDGGLKRAKVKDI 414

Query: 434 FKEEQQKLYSKMIVGN 449
           FKEEQQK YSKMIVGN
Sbjct: 415 FKEEQQKNYSKMIVGN 430


>gi|47086907 lysophosphatidylcholine acyltransferase 2 [Homo
           sapiens]
          Length = 544

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 45/174 (25%), Positives = 76/174 (43%), Gaps = 4/174 (2%)

Query: 246 ANHTSPIDVIILASDGYYAMVGQVHGGLMGVIQRAMVKACPHVWFERSEVKDRHLVAKRL 305
           A H++  D I     G  +MV +     + +I R +++A   V   R +   R      +
Sbjct: 144 APHSTFFDGIACVVAGLPSMVSRNENAQVPLIGR-LLRAVQPVLVSRVDPDSRKNTINEI 202

Query: 306 TEHVQDKSKLP-ILIFPEGTCINNTSVMMFKKGSFEIGATVYPVAIKYDPQFGDAFWNSS 364
            +      + P IL+FPEGTC N + ++ FK G+F  G  V PV ++Y  +     W   
Sbjct: 203 IKRTTSGGEWPQILVFPEGTCTNRSCLITFKPGAFIPGVPVQPVLLRYPNKLDTVTWTWQ 262

Query: 365 KYGMVTYLLRMMTSWAIVCSVWYLPPMTREADE--DAVQFANRVKSAIARQGGL 416
            Y  +   +           V ++P      +E  D V FAN+V++ +A   G+
Sbjct: 263 GYTFIQLCMLTFCQLFTKVEVEFMPVQVPNDEEKNDPVLFANKVRNLMAEALGI 316


>gi|33946291 lysophosphatidylcholine acyltransferase 1 [Homo
           sapiens]
          Length = 534

 Score = 59.7 bits (143), Expect = 5e-09
 Identities = 37/132 (28%), Positives = 61/132 (46%), Gaps = 3/132 (2%)

Query: 288 VWFERSEVKDRHLVAKRLTEHVQDKSKLP-ILIFPEGTCINNTSVMMFKKGSFEIGATVY 346
           V+  RS+   R    + +    Q   K P I+IFPEGTC N T ++ FK G+F  GA V 
Sbjct: 173 VFVSRSDQDSRRKTVEEIKRRAQSNGKWPQIMIFPEGTCTNRTCLITFKPGAFIPGAPVQ 232

Query: 347 PVAIKYDPQFGDAFWNSSKYGMVTYLLRMMTSWAIVCSVWYLPPMTREADE--DAVQFAN 404
           PV ++Y  +     W     G +  L   +  +     + +LP  +   +E  +   +A+
Sbjct: 233 PVVLRYPNKLDTITWTWQGPGALEILWLTLCQFHNQVEIEFLPVYSPSEEEKRNPALYAS 292

Query: 405 RVKSAIARQGGL 416
            V+  +A   G+
Sbjct: 293 NVRRVMAEALGV 304


>gi|87116681 lysophosphatidylcholine acyltransferase 4 [Homo
           sapiens]
          Length = 524

 Score = 59.3 bits (142), Expect = 7e-09
 Identities = 62/265 (23%), Positives = 111/265 (41%), Gaps = 20/265 (7%)

Query: 170 IRYCFL----LPLRIALAFTGISLL-VVGTTVVGYLPNGRFKEFMSKHVHLMCYRICVRA 224
           +++C L     P+R+ LAF  + LL       V  L   + +E ++     +C+   V  
Sbjct: 37  VKFCLLGALLAPIRVLLAFIVLFLLWPFAWLQVAGLSEEQLQEPITGWRKTVCHN-GVLG 95

Query: 225 LTAIITY----------HDRENRPRNGGICVANHTSPIDVIILASDGYYAMVGQVHGGLM 274
           L+ ++ +            R +R +   +  A H++  D I+L       +V +     +
Sbjct: 96  LSRLLFFLLGFLRIRVRGQRASRLQAPVLVAAPHSTFFDPIVLLPCDLPKVVSRAENLSV 155

Query: 275 GVIQRAMVKACPHVWFERSEVKDRHLVAKRLTEHVQDKSKLP-ILIFPEGTCINNTSVMM 333
            VI  A+++    +   R +   R  V + +        K P +L FPEGTC N  +++ 
Sbjct: 156 PVIG-ALLRFNQAILVSRHDPASRRRVVEEVRRRATSGGKWPQVLFFPEGTCSNKKALLK 214

Query: 334 FKKGSFEIGATVYPVAIKYDPQFGDAFWNSSKYGMVTYLLRMMTSWAIVCSVWYLPPM-- 391
           FK G+F  G  V PV I+Y        W     G++  L    +    +  V +LP    
Sbjct: 215 FKPGAFIAGVPVQPVLIRYPNSLDTTSWAWRGPGVLKVLWLTASQPCSIVDVEFLPVYHP 274

Query: 392 TREADEDAVQFANRVKSAIARQGGL 416
           + E   D   +AN V+  +A+  G+
Sbjct: 275 SPEESRDPTLYANNVQRVMAQALGI 299


>gi|5453718 1-acylglycerol-3-phosphate O-acyltransferase 1 [Homo
           sapiens]
          Length = 283

 Score = 33.9 bits (76), Expect = 0.31
 Identities = 39/185 (21%), Positives = 76/185 (41%), Gaps = 32/185 (17%)

Query: 238 PRNGGICVANHTSPIDVIILASDGYYAMVGQVHGGLMGVIQRAMVKA---------CPHV 288
           P    + V+NH S +D++         M+  + G  + + +R ++ A            +
Sbjct: 94  PSQPYVVVSNHQSSLDLL--------GMMEVLPGRCVPIAKRELLWAGSAGLACWLAGVI 145

Query: 289 WFERSEVKDRHLVAKRLTEHVQDKSKLPILIFPEGTCINNTSVMMFKKGSFEIGATV-YP 347
           + +R    D   V   + + +  +  + + +FPEGT  +N S++ FK+G+F +      P
Sbjct: 146 FIDRKRTGDAISVMSEVAQTLLTQD-VRVWVFPEGTRNHNGSMLPFKRGAFHLAVQAQVP 204

Query: 348 VAIKYDPQFGDAFWNSSKYGMVTYLLRMMTSWAIVCSVWYLPPMTRE--ADEDAVQFANR 405
           +       + D +             R  TS    C V  LPP+  E    +D    A+R
Sbjct: 205 IVPIVMSSYQDFYCKKE---------RRFTSGQ--CQVRVLPPVPTEGLTPDDVPALADR 253

Query: 406 VKSAI 410
           V+ ++
Sbjct: 254 VRHSM 258


>gi|15100175 1-acylglycerol-3-phosphate O-acyltransferase 1 [Homo
           sapiens]
          Length = 283

 Score = 33.9 bits (76), Expect = 0.31
 Identities = 39/185 (21%), Positives = 76/185 (41%), Gaps = 32/185 (17%)

Query: 238 PRNGGICVANHTSPIDVIILASDGYYAMVGQVHGGLMGVIQRAMVKA---------CPHV 288
           P    + V+NH S +D++         M+  + G  + + +R ++ A            +
Sbjct: 94  PSQPYVVVSNHQSSLDLL--------GMMEVLPGRCVPIAKRELLWAGSAGLACWLAGVI 145

Query: 289 WFERSEVKDRHLVAKRLTEHVQDKSKLPILIFPEGTCINNTSVMMFKKGSFEIGATV-YP 347
           + +R    D   V   + + +  +  + + +FPEGT  +N S++ FK+G+F +      P
Sbjct: 146 FIDRKRTGDAISVMSEVAQTLLTQD-VRVWVFPEGTRNHNGSMLPFKRGAFHLAVQAQVP 204

Query: 348 VAIKYDPQFGDAFWNSSKYGMVTYLLRMMTSWAIVCSVWYLPPMTRE--ADEDAVQFANR 405
           +       + D +             R  TS    C V  LPP+  E    +D    A+R
Sbjct: 205 IVPIVMSSYQDFYCKKE---------RRFTSGQ--CQVRVLPPVPTEGLTPDDVPALADR 253

Query: 406 VKSAI 410
           V+ ++
Sbjct: 254 VRHSM 258


>gi|6041665 1-acylglycerol-3-phosphate O-acyltransferase 2 isoform a
           [Homo sapiens]
          Length = 278

 Score = 31.2 bits (69), Expect = 2.0
 Identities = 15/54 (27%), Positives = 27/54 (50%)

Query: 312 KSKLPILIFPEGTCINNTSVMMFKKGSFEIGATVYPVAIKYDPQFGDAFWNSSK 365
           +  L + I+PEGT  +N  ++ FKKG+F +        +        +F+N+ K
Sbjct: 162 RENLKVWIYPEGTRNDNGDLLPFKKGAFYLAVQAQVPIVPVVYSSFSSFYNTKK 215


>gi|239735569 grainyhead-like 1 [Homo sapiens]
          Length = 618

 Score = 30.0 bits (66), Expect = 4.5
 Identities = 12/34 (35%), Positives = 20/34 (58%)

Query: 106 NTPEFELSDIFYFCRKGMETIMDDEVTKRFSAEE 139
           + P  ++  IF  C+KG+   MDD + K +S E+
Sbjct: 565 DVPHDKIGKIFKKCKKGILVNMDDNIVKHYSNED 598


>gi|209862760 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11,
           17.3kDa isoform 2 [Homo sapiens]
          Length = 153

 Score = 29.6 bits (65), Expect = 5.9
 Identities = 17/38 (44%), Positives = 25/38 (65%), Gaps = 2/38 (5%)

Query: 184 FTGISL-LVVGTTVVGYLPNGRFKEFMSKHV-HLMCYR 219
           F G+S+ LV+G+T V YLP+ R KE+  +    L+ YR
Sbjct: 92  FFGVSIILVLGSTFVAYLPDYRMKEWSRREAERLVKYR 129


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.140    0.425 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,999,047
Number of Sequences: 37866
Number of extensions: 668306
Number of successful extensions: 1975
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 1965
Number of HSP's gapped (non-prelim): 10
length of query: 456
length of database: 18,247,518
effective HSP length: 106
effective length of query: 350
effective length of database: 14,233,722
effective search space: 4981802700
effective search space used: 4981802700
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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