BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|30089966 CDC42 effector protein 5 [Homo sapiens] (148 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|30089966 CDC42 effector protein 5 [Homo sapiens] 309 6e-85 gi|23238226 CDC42 effector protein 1 [Homo sapiens] 76 1e-14 gi|13786127 Cdc42 effector protein 4 [Homo sapiens] 70 5e-13 gi|5802998 Cdc42 effector protein 2 [Homo sapiens] 52 2e-07 gi|19923356 Cdc42 effector protein 3 [Homo sapiens] 45 2e-05 gi|156071470 hyperpolarization activated cyclic nucleotide-gated... 44 4e-05 gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo sapi... 44 4e-05 gi|120587019 zinc finger protein 318 [Homo sapiens] 44 4e-05 gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 44 6e-05 gi|122692281 hypothetical protein LOC645369 [Homo sapiens] 44 6e-05 gi|224465238 hypothetical protein LOC283999 [Homo sapiens] 43 1e-04 gi|237757312 synaptojanin 1 isoform c [Homo sapiens] 43 1e-04 gi|6382071 diaphanous 2 isoform 12C [Homo sapiens] 43 1e-04 gi|5803003 diaphanous 2 isoform 156 [Homo sapiens] 43 1e-04 gi|239745177 PREDICTED: hypothetical protein XP_002343381 [Homo ... 42 1e-04 gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 42 1e-04 gi|56549694 enabled homolog isoform a [Homo sapiens] 42 2e-04 gi|39930375 enabled homolog isoform b [Homo sapiens] 42 2e-04 gi|47132519 Ras association and pleckstrin homology domains 1 is... 41 3e-04 gi|22027541 programmed cell death 7 [Homo sapiens] 41 3e-04 gi|153792074 proline rich 12 [Homo sapiens] 41 3e-04 gi|126090663 zinc finger homeodomain 4 [Homo sapiens] 41 4e-04 gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho... 41 4e-04 gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 40 5e-04 gi|52485606 formin-like 2 [Homo sapiens] 40 5e-04 gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 40 0.001 gi|122937267 lemur tyrosine kinase 3 [Homo sapiens] 40 0.001 gi|115334682 SNAP25-interacting protein [Homo sapiens] 40 0.001 gi|124107614 PR domain containing 13 [Homo sapiens] 40 0.001 gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] 39 0.001 >gi|30089966 CDC42 effector protein 5 [Homo sapiens] Length = 148 Score = 309 bits (791), Expect = 6e-85 Identities = 148/148 (100%), Positives = 148/148 (100%) Query: 1 MPVLKQLGPAQPKKRPDRGALSISAPLGDFRHTLHVGRGGDAFGDTSFLSRHGGGPPPEP 60 MPVLKQLGPAQPKKRPDRGALSISAPLGDFRHTLHVGRGGDAFGDTSFLSRHGGGPPPEP Sbjct: 1 MPVLKQLGPAQPKKRPDRGALSISAPLGDFRHTLHVGRGGDAFGDTSFLSRHGGGPPPEP 60 Query: 61 RAPPAGAPRSPPPPAVPQSAAPSPADPLLSFHLDLGPSMLDAVLGVMDAARPEAAAAKPD 120 RAPPAGAPRSPPPPAVPQSAAPSPADPLLSFHLDLGPSMLDAVLGVMDAARPEAAAAKPD Sbjct: 61 RAPPAGAPRSPPPPAVPQSAAPSPADPLLSFHLDLGPSMLDAVLGVMDAARPEAAAAKPD 120 Query: 121 AEPRPGTQPPQARCRPNADLELNDVIGL 148 AEPRPGTQPPQARCRPNADLELNDVIGL Sbjct: 121 AEPRPGTQPPQARCRPNADLELNDVIGL 148 >gi|23238226 CDC42 effector protein 1 [Homo sapiens] Length = 391 Score = 75.9 bits (185), Expect = 1e-14 Identities = 39/76 (51%), Positives = 45/76 (59%), Gaps = 8/76 (10%) Query: 23 ISAPLGDFRHTLHVGRGGDAFGDTSFLSRHGGGPPPEPRAPPAGAPR--------SPPPP 74 IS PLGDFRHT+HVGRGGD FGDTSFLS HGG R+P + + PP Sbjct: 38 ISHPLGDFRHTMHVGRGGDVFGDTSFLSNHGGSSGSTHRSPRSFLAKKLQLVRRVGAPPR 97 Query: 75 AVPQSAAPSPADPLLS 90 + APSPA P +S Sbjct: 98 RMASPPAPSPAPPAIS 113 Score = 41.2 bits (95), Expect = 3e-04 Identities = 31/77 (40%), Positives = 37/77 (48%), Gaps = 13/77 (16%) Query: 68 PRSPPPP------AVPQSAAPSPADPLLSFHLDL--GPSMLDAVLGVMDAARPEAAAAKP 119 PRS P + P +D LLSF LDL GPS+L +LGVM + PEA AA+ Sbjct: 167 PRSEKPHDRDRDGSFPSEPGLRRSDSLLSFRLDLDLGPSLLSELLGVM--SLPEAPAAE- 223 Query: 120 DAEPRPGTQPPQARCRP 136 P P PP P Sbjct: 224 --TPAPAANPPAPTANP 238 Score = 27.3 bits (59), Expect = 4.8 Identities = 25/82 (30%), Positives = 29/82 (35%), Gaps = 25/82 (30%) Query: 57 PPEPRAPPAGAPRSPP-PPAVPQSAAPSPADPLLSFHLDLGPSMLDAVLGVMDAARPEAA 115 PP P A P G +PP A P + A +P+ P AA P Sbjct: 231 PPAPTANPTGPAANPPATTANPPAPAANPSAP---------------------AATPTGP 269 Query: 116 AAKPDAEPRPGTQPPQARCRPN 137 AA P A T P C PN Sbjct: 270 AANPPAPAASST--PHGHC-PN 288 >gi|13786127 Cdc42 effector protein 4 [Homo sapiens] Length = 356 Score = 70.5 bits (171), Expect = 5e-13 Identities = 37/63 (58%), Positives = 43/63 (68%), Gaps = 4/63 (6%) Query: 1 MPVLKQLGPA----QPKKRPDRGALSISAPLGDFRHTLHVGRGGDAFGDTSFLSRHGGGP 56 MP+LKQL + + + R D A ISAPLGDFRHT+HVGR GDAFGDTSFL+ G P Sbjct: 1 MPILKQLVSSSVHSKRRSRADLTAEMISAPLGDFRHTMHVGRAGDAFGDTSFLNSKAGEP 60 Query: 57 PPE 59 E Sbjct: 61 DGE 63 Score = 45.1 bits (105), Expect = 2e-05 Identities = 42/133 (31%), Positives = 50/133 (37%), Gaps = 36/133 (27%) Query: 37 GRGGDAFGDTSFLSRHGGGPPPEPRAPPAGAPRSPPP-------------PAVPQSA-AP 82 G GGD G PR A P SP P P VP++ Sbjct: 150 GEGGD---------EEAGTEEAVPRRNGAAGPHSPDPLLDEQAFGDLTDLPVVPKATYGL 200 Query: 83 SPADPLLSFHLDLGPSMLDAVLGVMDAAR--PE-----------AAAAKPDAEPRPGTQP 129 A+ ++SFH+DLGPSML VL +MD PE AA A P P Sbjct: 201 KHAESIMSFHIDLGPSMLGDVLSIMDKEEWDPEEGEGGYHGDEGAAGTITQAPPYAVAAP 260 Query: 130 PQARCRPNADLEL 142 P AR A +L Sbjct: 261 PLARQEGKAGPDL 273 >gi|5802998 Cdc42 effector protein 2 [Homo sapiens] Length = 210 Score = 52.0 bits (123), Expect = 2e-07 Identities = 57/196 (29%), Positives = 74/196 (37%), Gaps = 88/196 (44%) Query: 1 MPVLKQLGPAQPKKRPDRGALS---ISAPLGDFRHTLHVGRGG--DAFGDTSFLS----- 50 +P+ + G + KK R LS IS PLGDFRHT+H+G GG D FGD SFL Sbjct: 5 VPIYLKRGSRKGKKEKLRDLLSSDMISPPLGDFRHTIHIGSGGGSDMFGDISFLQGKFHL 64 Query: 51 ------------------------------RHGGGPPP------------EPRA---PPA 65 GP P P+A P A Sbjct: 65 LPGTMVEGPEEDGTFDLPFQFTRTATVCGRELPDGPSPLLKNAISLPVIGGPQALTLPTA 124 Query: 66 GAPRSP-------PPPA-----------VPQSAAPSPA--------DPLLS-------FH 92 AP P P P+ +P++ +P+ +P LS H Sbjct: 125 QAPPKPPRLHLETPQPSPQEGGSVDIWRIPETGSPNSGLTPESGAEEPFLSNASSLLSLH 184 Query: 93 LDLGPSMLDAVLGVMD 108 +DLGPS+LD VL +MD Sbjct: 185 VDLGPSILDDVLQIMD 200 >gi|19923356 Cdc42 effector protein 3 [Homo sapiens] Length = 254 Score = 45.1 bits (105), Expect = 2e-05 Identities = 27/51 (52%), Positives = 31/51 (60%), Gaps = 5/51 (9%) Query: 4 LKQLGPAQPKKRPDRGALS---ISAPLGDFRHTLHVGRGG--DAFGDTSFL 49 LK + KK R LS IS PLGDFRHT+H+G+ G D FGD SFL Sbjct: 9 LKAANNKKGKKFKLRDILSPDMISPPLGDFRHTIHIGKEGQHDVFGDISFL 59 Score = 34.3 bits (77), Expect = 0.039 Identities = 16/21 (76%), Positives = 17/21 (80%) Query: 88 LLSFHLDLGPSMLDAVLGVMD 108 LLS LDLGPS+LD VL VMD Sbjct: 231 LLSLQLDLGPSLLDEVLNVMD 251 >gi|156071470 hyperpolarization activated cyclic nucleotide-gated potassium channel 2 [Homo sapiens] Length = 889 Score = 44.3 bits (103), Expect = 4e-05 Identities = 30/84 (35%), Positives = 32/84 (38%), Gaps = 22/84 (26%) Query: 50 SRHGGGPPPE-PRAPPAGAPRSPPPPAVPQSAAPSPADPLLSFHLDLGPSMLDAVLGVMD 108 +R GGG P E P A PA P PPPPA PQ P P P Sbjct: 3 ARGGGGRPGESPGATPAPGPPPPPPPAPPQQQPPPPPPP--------------------- 41 Query: 109 AARPEAAAAKPDAEPRPGTQPPQA 132 A P A P PR PP+A Sbjct: 42 APPPGPGPAPPQHPPRAEALPPEA 65 Score = 43.9 bits (102), Expect = 5e-05 Identities = 20/46 (43%), Positives = 24/46 (52%) Query: 39 GGDAFGDTSFLSRHGGGPPPEPRAPPAGAPRSPPPPAVPQSAAPSP 84 GG G++ + G PPP P APP P PPPPA P P+P Sbjct: 6 GGGRPGESPGATPAPGPPPPPPPAPPQQQPPPPPPPAPPPGPGPAP 51 Score = 38.1 bits (87), Expect = 0.003 Identities = 31/85 (36%), Positives = 38/85 (44%), Gaps = 9/85 (10%) Query: 56 PPPEPRAPPAGAPRSPPPPAVPQSAAPSPADPLLSFHLDLGPSMLDAVLGVMDAARPEAA 115 PPP P PA A PPPPA P A SP P S + L + L G AR + Sbjct: 761 PPPGPA--PAAASPGPPPPASPPGAPASPRAPRTSPYGGLPAAPL---AGPALPARRLSR 815 Query: 116 AAKPDAEPRP----GTQPPQARCRP 136 A++P + +P G P A RP Sbjct: 816 ASRPLSASQPSLPHGAPGPAASTRP 840 Score = 32.7 bits (73), Expect = 0.11 Identities = 32/113 (28%), Positives = 46/113 (40%), Gaps = 16/113 (14%) Query: 42 AFGDTSFLSRHGGGPPPEPRAPPAGAPRSPP-PPAVPQSAAPSPADPLLSFHLDLGPSM- 99 A G + R GP P +P P SPP PA P++ SP L + L GP++ Sbjct: 751 ALGSPRLVRRPPPGPAPAAASPGPPPPASPPGAPASPRAPRTSPYGGLPAAPL-AGPALP 809 Query: 100 ---LDAVLGVMDAARPE--------AAAAKP--DAEPRPGTQPPQARCRPNAD 139 L + A++P AA+ +P + PR G P P+ D Sbjct: 810 ARRLSRASRPLSASQPSLPHGAPGPAASTRPASSSTPRLGPTPAARAAAPSPD 862 Score = 29.6 bits (65), Expect = 0.96 Identities = 12/31 (38%), Positives = 14/31 (45%) Query: 56 PPPEPRAPPAGAPRSPPPPAVPQSAAPSPAD 86 PPP P PP P P P ++ P AD Sbjct: 37 PPPPPAPPPGPGPAPPQHPPRAEALPPEAAD 67 >gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo sapiens] Length = 729 Score = 44.3 bits (103), Expect = 4e-05 Identities = 28/87 (32%), Positives = 35/87 (40%), Gaps = 7/87 (8%) Query: 44 GDTSFLSRHGGGPPPEPRAPPAGAPRSPPPPAVPQSAAPSPADPLLSFHLDLGPSMLDAV 103 G S S G P P P+ P AP S PP P A P PA P P+ ++ Sbjct: 305 GAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACP-------SAPAPRRSI 357 Query: 104 LGVMDAARPEAAAAKPDAEPRPGTQPP 130 + + P AA P EP P + P Sbjct: 358 ISRLFGTSPATEAAPPPPEPVPAAEGP 384 Score = 26.9 bits (58), Expect = 6.2 Identities = 31/106 (29%), Positives = 40/106 (37%), Gaps = 22/106 (20%) Query: 58 PEPRAPPAGAPR---------------SPPPPAVPQSAAPSPA--DPLLSFHLD--LGPS 98 P P P A APR + PPP P AA PA + F D L S Sbjct: 343 PPPACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSVEDFVPDDRLDRS 402 Query: 99 MLDAVLGVMDAARPEAAAAKPDAE---PRPGTQPPQARCRPNADLE 141 L+ D + A AA+ D++ G P A + + DLE Sbjct: 403 FLEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLE 448 >gi|120587019 zinc finger protein 318 [Homo sapiens] Length = 2279 Score = 44.3 bits (103), Expect = 4e-05 Identities = 33/87 (37%), Positives = 44/87 (50%), Gaps = 23/87 (26%) Query: 56 PPPEPRAPPAGAPRSPPPPAVPQSAAPSPA-----------DPLLSFHLD---LGPSMLD 101 PPP P PP PPPP +P AAPS A +P++S L +GP++L+ Sbjct: 1442 PPPPPPPPPP----PPPPPVIPHPAAPSAAQANAILAPVKSNPVVSQTLSPGFVGPNILN 1497 Query: 102 AVL--GVMDAARPEAAAAKPDAEPRPG 126 VL +M +A+P AA P E PG Sbjct: 1498 PVLPVAIMASAQP---AAIPSDETAPG 1521 Score = 27.3 bits (59), Expect = 4.8 Identities = 19/60 (31%), Positives = 25/60 (41%), Gaps = 10/60 (16%) Query: 38 RGGDAFGDTSFLSRHGGGPPP---EPRAPPAGAPRSP-------PPPAVPQSAAPSPADP 87 R G + G +S +R PPP PA PRSP P+ P+ SP+ P Sbjct: 24 RSGRSSGSSSGPARRSSPPPPPSGSSSRTPARRPRSPSGHRGRRASPSPPRGRRVSPSPP 83 >gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sapiens] Length = 505 Score = 43.5 bits (101), Expect = 6e-05 Identities = 33/90 (36%), Positives = 36/90 (40%), Gaps = 14/90 (15%) Query: 50 SRHGGGPPPEPRAPPAGAPRSPPPPAVPQSAAP--------SPADPLLSFHLDLG-PSML 100 +R G PPP P P AP PPPP+ P A P P P L G P Sbjct: 304 ARGRGAPPPPPSRAPTAAP-PPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPP 362 Query: 101 DAVLGVMDAARPEAAAAKPDAEPRPGTQPP 130 +VLGV P A P P PG PP Sbjct: 363 PSVLGV----GPVAPPPPPPPPPPPGPPPP 388 Score = 35.4 bits (80), Expect = 0.018 Identities = 23/76 (30%), Positives = 27/76 (35%) Query: 50 SRHGGGPPPEPRAPPAGAPRSPPPPAVPQSAAPSPADPLLSFHLDLGPSMLDAVLGVMDA 109 S G PPP P G PPPP P P P L S P+ ++D Sbjct: 353 SAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPPGLPSDGDHQVPTTAGNKAALLDQ 412 Query: 110 ARPEAAAAKPDAEPRP 125 R A K + RP Sbjct: 413 IREGAQLKKVEQNSRP 428 Score = 33.5 bits (75), Expect = 0.067 Identities = 19/41 (46%), Positives = 20/41 (48%), Gaps = 9/41 (21%) Query: 54 GGPPPEPRAPPAGAPRSPPPPA-------VPQSAAPSPADP 87 GGPPP P P P PPPPA P S AP+ A P Sbjct: 285 GGPPPPPPPPHNSGP--PPPPARGRGAPPPPPSRAPTAAPP 323 Score = 30.0 bits (66), Expect = 0.74 Identities = 14/29 (48%), Positives = 16/29 (55%), Gaps = 4/29 (13%) Query: 56 PPPEPRAPPAGAPRSPPPPAVPQSAAPSP 84 PPP P P G P PPPP P ++ P P Sbjct: 277 PPPPP--PSRGGP--PPPPPPPHNSGPPP 301 >gi|122692281 hypothetical protein LOC645369 [Homo sapiens] Length = 621 Score = 43.5 bits (101), Expect = 6e-05 Identities = 34/104 (32%), Positives = 43/104 (41%), Gaps = 22/104 (21%) Query: 37 GRGGDAFGDTSFLSRHGGGPPPEPRAPPAGAPRSPPPPAVPQSAAPSPADPLLSFHLDLG 96 G GDAFG + L++ G PP P AP G PR P S+ P +P Sbjct: 267 GGSGDAFGAAAMLAK--GSWPPHPAAPSGGRPRGAASPPDLASSPRCPREP--------- 315 Query: 97 PSMLDAVLGV-----------MDAARPEAAAAKPDAEPRPGTQP 129 PS+ +AV V AA AAAA + P P + P Sbjct: 316 PSLAEAVYSVYRERSGVAGSRRAAAATAAAAASSCSSPAPCSPP 359 Score = 29.3 bits (64), Expect = 1.3 Identities = 14/32 (43%), Positives = 18/32 (56%), Gaps = 2/32 (6%) Query: 57 PPEPRAPPAGAPRSPPPPAVPQSAAPSPADPL 88 PP P PP +P S P + P + A SP+ PL Sbjct: 481 PPSPEPPP--SPGSADPDSSPLAKAASPSPPL 510 >gi|224465238 hypothetical protein LOC283999 [Homo sapiens] Length = 394 Score = 42.7 bits (99), Expect = 1e-04 Identities = 27/75 (36%), Positives = 32/75 (42%), Gaps = 4/75 (5%) Query: 9 PAQPKKRPDRGALSISAPLGDFRHTLHVGRGGDAFGDTSFLSRHGGGPPPEPRAPPAGAP 68 P +RP RG + + A G R GR GD R PPP PR P AP Sbjct: 110 PQGRAQRPQRGGVDLPATPGGPRGQC-AGRSGDVLRRAG---RRRARPPPVPRLPAPRAP 165 Query: 69 RSPPPPAVPQSAAPS 83 R P PA P + P+ Sbjct: 166 RRPRGPATPDPSPPA 180 >gi|237757312 synaptojanin 1 isoform c [Homo sapiens] Length = 1295 Score = 42.7 bits (99), Expect = 1e-04 Identities = 29/92 (31%), Positives = 41/92 (44%), Gaps = 9/92 (9%) Query: 56 PPPEPRAPPA--GAPRSPPPPAVPQSAAP------SPADPLLSFHLDLGPSMLDAVLGVM 107 PPP P APP P+ PPPP+ +S AP +P P + ++G S G+ Sbjct: 1109 PPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGAPKSPGTTRKDNIGRSQPSPQAGLA 1168 Query: 108 DAARPEAAAAKPDAEPRPGT-QPPQARCRPNA 138 + A+P PR G PQ+ R +A Sbjct: 1169 GPGPAGYSTARPTIPPRAGVISAPQSHARASA 1200 >gi|6382071 diaphanous 2 isoform 12C [Homo sapiens] Length = 1096 Score = 42.7 bits (99), Expect = 1e-04 Identities = 22/41 (53%), Positives = 23/41 (56%), Gaps = 4/41 (9%) Query: 53 GGGPPPEPRAPP--AGAPRSPPPPAVP--QSAAPSPADPLL 89 G GPPP P APP GAP PPPP +P P P PLL Sbjct: 559 GVGPPPPPPAPPLPGGAPLPPPPPPLPGMMGIPPPPPPPLL 599 Score = 34.7 bits (78), Expect = 0.030 Identities = 22/76 (28%), Positives = 26/76 (34%), Gaps = 11/76 (14%) Query: 55 GPPPEPRAPPAGAPRSPPPPAVPQSAAPSPADPLLSFHLDLGPSMLDAVLGVMDAARPEA 114 GPP P P G P PP P +P A P P L ++G+ P Sbjct: 550 GPPAAPPLPGVGPPPPPPAPPLPGGAPLPPP-----------PPPLPGMMGIPPPPPPPL 598 Query: 115 AAAKPDAEPRPGTQPP 130 P P G PP Sbjct: 599 LFGGPPPPPPLGGVPP 614 >gi|5803003 diaphanous 2 isoform 156 [Homo sapiens] Length = 1101 Score = 42.7 bits (99), Expect = 1e-04 Identities = 22/41 (53%), Positives = 23/41 (56%), Gaps = 4/41 (9%) Query: 53 GGGPPPEPRAPP--AGAPRSPPPPAVP--QSAAPSPADPLL 89 G GPPP P APP GAP PPPP +P P P PLL Sbjct: 559 GVGPPPPPPAPPLPGGAPLPPPPPPLPGMMGIPPPPPPPLL 599 Score = 34.7 bits (78), Expect = 0.030 Identities = 22/76 (28%), Positives = 26/76 (34%), Gaps = 11/76 (14%) Query: 55 GPPPEPRAPPAGAPRSPPPPAVPQSAAPSPADPLLSFHLDLGPSMLDAVLGVMDAARPEA 114 GPP P P G P PP P +P A P P L ++G+ P Sbjct: 550 GPPAAPPLPGVGPPPPPPAPPLPGGAPLPPP-----------PPPLPGMMGIPPPPPPPL 598 Query: 115 AAAKPDAEPRPGTQPP 130 P P G PP Sbjct: 599 LFGGPPPPPPLGGVPP 614 >gi|239745177 PREDICTED: hypothetical protein XP_002343381 [Homo sapiens] Length = 252 Score = 42.4 bits (98), Expect = 1e-04 Identities = 32/86 (37%), Positives = 37/86 (43%), Gaps = 13/86 (15%) Query: 62 APPAGAPRSPPPPAVPQSAAPSPADPLLSFHLDL------GPSMLDAV------LGVMDA 109 A AGA R+P PPA P S PADPLL P A G + Sbjct: 131 AGAAGAARAPKPPA-PGSGQALPADPLLQAAASTLAGRPRAPPPAPAAGQRGLGSGALGL 189 Query: 110 ARPEAAAAKPDAEPRPGTQPPQARCR 135 R E AA+P A PR ++PP CR Sbjct: 190 GRREKLAARPAATPRRASRPPWQGCR 215 >gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] Length = 538 Score = 42.4 bits (98), Expect = 1e-04 Identities = 31/93 (33%), Positives = 34/93 (36%), Gaps = 21/93 (22%) Query: 51 RHGGGPPPEPRAP---PAGAPRSPPPPAVPQSAAPSPADPLLSFHLDLGPSMLDAVLGVM 107 R G PP PRAP PA A + PPP P+P V Sbjct: 103 RRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAP------------------VAAAA 144 Query: 108 DAARPEAAAAKPDAEPRPGTQPPQARCRPNADL 140 A P AAAA A P PG P R + A L Sbjct: 145 PARAPRAAAAAATAPPSPGPAQPGPRAQRAAPL 177 Score = 37.4 bits (85), Expect = 0.005 Identities = 19/36 (52%), Positives = 19/36 (52%), Gaps = 4/36 (11%) Query: 56 PPPEPRAPPAGA----PRSPPPPAVPQSAAPSPADP 87 PPP P APPA A PR PPPAV P P P Sbjct: 180 PPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPP 215 Score = 32.3 bits (72), Expect = 0.15 Identities = 40/153 (26%), Positives = 53/153 (34%), Gaps = 23/153 (15%) Query: 8 GPAQPKKRPDRGA-LSISAPLGDFRHTLHVGRGGDAFGDTSFLSRHGG-GPPPEPRAPPA 65 GPAQP R R A L+ P + G + +R PPP+P APP Sbjct: 163 GPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQ 222 Query: 66 GAPRSPPPPAVPQ---------SAAPSPADPLLSFHLDLGPSMLDAVLGVMDAARPEAAA 116 PP P P +A P ++ + G + G + E AA Sbjct: 223 QQQPPPPQPQPPPEGGAVRAGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQGLLEEEAA 282 Query: 117 AKPDAE------------PRPGTQPPQARCRPN 137 A+ E RPG PP A RP+ Sbjct: 283 ARGRLERTRLGALALPRGDRPGRAPPAASARPS 315 >gi|56549694 enabled homolog isoform a [Homo sapiens] Length = 591 Score = 42.0 bits (97), Expect = 2e-04 Identities = 16/33 (48%), Positives = 17/33 (51%) Query: 55 GPPPEPRAPPAGAPRSPPPPAVPQSAAPSPADP 87 GPPP P P G P PPPP +P P P P Sbjct: 335 GPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPPP 367 Score = 34.3 bits (77), Expect = 0.039 Identities = 16/31 (51%), Positives = 16/31 (51%), Gaps = 2/31 (6%) Query: 55 GPPPEPRAPPAGAPRSPPPPAVPQSAAPSPA 85 GPPP P PP P PPP P A P PA Sbjct: 346 GPPPPP--PPPPLPNQVPPPPPPPPAPPLPA 374 Score = 30.0 bits (66), Expect = 0.74 Identities = 17/40 (42%), Positives = 17/40 (42%), Gaps = 8/40 (20%) Query: 56 PPPEPRAPPAGAPRS---PPPPAVP-----QSAAPSPADP 87 PPP P PP A S PPPP P S P P P Sbjct: 313 PPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPPP 352 >gi|39930375 enabled homolog isoform b [Homo sapiens] Length = 570 Score = 42.0 bits (97), Expect = 2e-04 Identities = 16/33 (48%), Positives = 17/33 (51%) Query: 55 GPPPEPRAPPAGAPRSPPPPAVPQSAAPSPADP 87 GPPP P P G P PPPP +P P P P Sbjct: 335 GPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPPP 367 Score = 34.3 bits (77), Expect = 0.039 Identities = 16/31 (51%), Positives = 16/31 (51%), Gaps = 2/31 (6%) Query: 55 GPPPEPRAPPAGAPRSPPPPAVPQSAAPSPA 85 GPPP P PP P PPP P A P PA Sbjct: 346 GPPPPP--PPPPLPNQVPPPPPPPPAPPLPA 374 Score = 30.0 bits (66), Expect = 0.74 Identities = 17/40 (42%), Positives = 17/40 (42%), Gaps = 8/40 (20%) Query: 56 PPPEPRAPPAGAPRS---PPPPAVP-----QSAAPSPADP 87 PPP P PP A S PPPP P S P P P Sbjct: 313 PPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPPP 352 >gi|47132519 Ras association and pleckstrin homology domains 1 isoform 1 [Homo sapiens] Length = 1250 Score = 41.2 bits (95), Expect = 3e-04 Identities = 26/84 (30%), Positives = 34/84 (40%), Gaps = 8/84 (9%) Query: 56 PPPEPRAPPAGAPRSPPPPAVPQSAAPSPADPLLSFHLDLGPSMLDAVLGVMDAARPEAA 115 PPP P PP P PPPP +P +APS F + + +A++ A Sbjct: 629 PPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMF------VKYSTITRLQNASQHSGA 682 Query: 116 AAKPDAEPRPGTQ--PPQARCRPN 137 KP P +Q PQ PN Sbjct: 683 LFKPPTPPVMQSQSVKPQILVPPN 706 Score = 35.0 bits (79), Expect = 0.023 Identities = 26/80 (32%), Positives = 30/80 (37%), Gaps = 8/80 (10%) Query: 57 PPEPRAPPAGAPRSPPPPAVPQSAA----PSPADPLL-SFHLDLGPSMLDAVLGVMDAAR 111 PP PP P PPPP P SA P+P P L F P + V + A Sbjct: 704 PPNGVVPP---PPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAP 760 Query: 112 PEAAAAKPDAEPRPGTQPPQ 131 P P P P PP+ Sbjct: 761 PTPPPPPPIPAPLPPQAPPK 780 Score = 34.3 bits (77), Expect = 0.039 Identities = 24/81 (29%), Positives = 32/81 (39%), Gaps = 16/81 (19%) Query: 56 PPPEPRAPPAGAPRSPPPPAVPQSAAPSPADPLLSFHLDLGPSMLDAVLGVMDAARPEAA 115 PPP P + A +P P++PQ +AP P P + V + A P Sbjct: 717 PPPTPGSAMAQLKPAPCAPSLPQFSAPPP------------PLKIHQVQHITQVAPP--- 761 Query: 116 AAKPDAEPRPGTQPPQARCRP 136 P P P PPQA +P Sbjct: 762 -TPPPPPPIPAPLPPQAPPKP 781 Score = 33.1 bits (74), Expect = 0.087 Identities = 16/34 (47%), Positives = 20/34 (58%), Gaps = 7/34 (20%) Query: 56 PPPE-----PRAPPAGAPRSPPPPAVPQSAAPSP 84 PPPE P PP+ P PPPP P +A+P+P Sbjct: 919 PPPESSLVFPPPPPSPVPAPPPPP--PPTASPTP 950 Score = 29.6 bits (65), Expect = 0.96 Identities = 14/34 (41%), Positives = 15/34 (44%) Query: 57 PPEPRAPPAGAPRSPPPPAVPQSAAPSPADPLLS 90 P P PP + PPPP P A P P P S Sbjct: 914 PDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTAS 947 Score = 28.1 bits (61), Expect = 2.8 Identities = 12/29 (41%), Positives = 13/29 (44%) Query: 56 PPPEPRAPPAGAPRSPPPPAVPQSAAPSP 84 PP P PP AP P P P P+P Sbjct: 760 PPTPPPPPPIPAPLPPQAPPKPLVTIPAP 788 Score = 28.1 bits (61), Expect = 2.8 Identities = 15/48 (31%), Positives = 20/48 (41%), Gaps = 15/48 (31%) Query: 56 PPPEPRAPPAGAPRSPP---------------PPAVPQSAAPSPADPL 88 PPP P P P++PP P V Q+A P+P P+ Sbjct: 763 PPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPV 810 Score = 26.9 bits (58), Expect = 6.2 Identities = 28/92 (30%), Positives = 33/92 (35%), Gaps = 16/92 (17%) Query: 56 PPPEPRAPPAG------APRSPPPPAVPQSAAPSPADP-LLSFHLDLGPSMLDAVLGVM- 107 P P P PPA A PP P P P P P SF PS L V V+ Sbjct: 804 PTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVK 863 Query: 108 -------DAARPEAAAAKPDAEPRPGTQPPQA 132 P A ++P +P P PQ+ Sbjct: 864 QIASQFPPPPTPPAMESQP-LKPVPANVAPQS 894 >gi|22027541 programmed cell death 7 [Homo sapiens] Length = 485 Score = 41.2 bits (95), Expect = 3e-04 Identities = 28/88 (31%), Positives = 32/88 (36%), Gaps = 5/88 (5%) Query: 54 GGPPPEPRAPPAGAPRSPPPPAVPQSAAPSPADPLLSFHLDLGPSMLDAVLGVMDAARPE 113 G P P P PP AP PPP +P A P P L L + A E Sbjct: 10 GRPGPPPPQPPPPAPFGCPPPPLPSPAFPPPLPQRPGPFPGASAPFLQPPLALQPRASAE 69 Query: 114 AAAAKPDA-----EPRPGTQPPQARCRP 136 A+ A P P PP +CRP Sbjct: 70 ASRGGGGAGAFYPVPPPPLPPPPPQCRP 97 >gi|153792074 proline rich 12 [Homo sapiens] Length = 2036 Score = 41.2 bits (95), Expect = 3e-04 Identities = 27/77 (35%), Positives = 30/77 (38%), Gaps = 14/77 (18%) Query: 56 PPPEPRAPPAGAPRSPPPPAVPQSAAPSPADPLLSFHLDLGPSMLDAVLGVMDAARPEAA 115 PPP P P P+ PPPP PQ A PSP PL++ P P Sbjct: 1457 PPPTPPPAPTPQPQPPPPPPPPQPALPSP-PPLVAPTPSSPPP-------------PPLP 1502 Query: 116 AAKPDAEPRPGTQPPQA 132 P A P P PP A Sbjct: 1503 PPPPPAMPSPPPPPPPA 1519 Score = 38.1 bits (87), Expect = 0.003 Identities = 21/43 (48%), Positives = 22/43 (51%), Gaps = 9/43 (20%) Query: 56 PPPEPRAPPAGAPRSPPPP---AVP------QSAAPSPADPLL 89 PPP P PP P PPPP A P + AAPSP DP L Sbjct: 1498 PPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPEL 1540 Score = 33.5 bits (75), Expect = 0.067 Identities = 27/91 (29%), Positives = 32/91 (35%), Gaps = 19/91 (20%) Query: 55 GPPPEPRAPPA---GAPRSP-----PPPAVPQSAAPSPADPLLSFHLDLGPSMLDAVLGV 106 GPPP P P A G P P PPP P + P P P P A+ Sbjct: 1432 GPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPP------PPPPPPQPAL--- 1482 Query: 107 MDAARPEAAAAKPDAEPRPGTQPPQARCRPN 137 + P A P + P P PP P+ Sbjct: 1483 --PSPPPLVAPTPSSPPPPPLPPPPPPAMPS 1511 Score = 32.0 bits (71), Expect = 0.19 Identities = 37/136 (27%), Positives = 48/136 (35%), Gaps = 38/136 (27%) Query: 11 QPKKRPDRGALSISAPLGDFRHTLHVGRGGDAFGDTSFLSRHGGGPPPEPRAPPAGAPRS 70 + KK P+RG P G +H G G G +FL + Sbjct: 727 EKKKGPERGG---ETPEGLATSVVHYGAGAKELG--AFLQKS-----------------P 764 Query: 71 PPPPAVPQSAAPSPADPLLSF---HLDL-----GPSMLDAVLGVMDAARPEAA------- 115 PPPP QS P+P LL L L P +L +VL + P A+ Sbjct: 765 PPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLL 824 Query: 116 -AAKPDAEPRPGTQPP 130 A D P+P PP Sbjct: 825 EPATRDGAPQPPPPPP 840 Score = 31.6 bits (70), Expect = 0.25 Identities = 24/84 (28%), Positives = 33/84 (39%), Gaps = 6/84 (7%) Query: 53 GGGPPPEPRAPPAGAPRSPPPPA------VPQSAAPSPADPLLSFHLDLGPSMLDAVLGV 106 G GPP PAGA RSP P VP ++ P L P+M + G Sbjct: 898 GVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGG 957 Query: 107 MDAARPEAAAAKPDAEPRPGTQPP 130 +A + + +P+ G PP Sbjct: 958 AADDYGKAGPPEDEGDPKAGAGPP 981 Score = 31.6 bits (70), Expect = 0.25 Identities = 28/98 (28%), Positives = 37/98 (37%), Gaps = 16/98 (16%) Query: 55 GPPPEPRAPPAGAPRSPPPPAVP--------QSAAPSPADPLLSFHLDLGPSMLDAV--- 103 GPP + P AGA P PPA +++ P P L + P + V Sbjct: 966 GPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAE 1025 Query: 104 -LGVMDAARPEAAAAKPDAEPRPGTQPPQARCRPNADL 140 LG++ + P AA P P P PP P L Sbjct: 1026 PLGLIQSG-PHQAAPPPPPPPPP---PPAPASEPKGGL 1059 Score = 30.8 bits (68), Expect = 0.43 Identities = 22/65 (33%), Positives = 27/65 (41%), Gaps = 12/65 (18%) Query: 31 RHTLHVGRGGDAFGDTSFLSRHGGGPPPEPRAP-PAGAPRSP-------PPPAVPQSAAP 82 R + V R G A S GG P P+AP P P +P PP P++A P Sbjct: 1669 RPPVPVRRSGQAKNPVSA----GGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMP 1724 Query: 83 SPADP 87 P P Sbjct: 1725 EPPAP 1729 Score = 30.0 bits (66), Expect = 0.74 Identities = 18/46 (39%), Positives = 20/46 (43%), Gaps = 6/46 (13%) Query: 37 GRGGDAFGDTSFLSRHGGGPPPEPRAPPAGAPRSPPPPAVPQSAAP 82 G GG D S + GGPP P PP PP A QS +P Sbjct: 460 GFGGGQAQDLSKAPSYSGGPPQPPSGPP------PPGLATCQSYSP 499 Score = 30.0 bits (66), Expect = 0.74 Identities = 26/77 (33%), Positives = 29/77 (37%), Gaps = 25/77 (32%) Query: 56 PPPEPRAPPAGAPRSPPPPAVPQSAAPSP--ADPLLSFHLDLGPSMLDAVLGVMDAARPE 113 P P PP P PPPPA+P P P A PL AA PE Sbjct: 1491 PTPSSPPPPPLPP--PPPPAMPSPPPPPPPAAAPL--------------------AAPPE 1528 Query: 114 AAAAKPDAEPR-PGTQP 129 AA +P P T+P Sbjct: 1529 EPAAPSPEDPELPDTRP 1545 Score = 29.6 bits (65), Expect = 0.96 Identities = 17/46 (36%), Positives = 18/46 (39%), Gaps = 4/46 (8%) Query: 52 HGGGPPPEPRAPPAGAPRSPPPPAVPQ----SAAPSPADPLLSFHL 93 H PPP P PP AP S P + S P SFHL Sbjct: 1035 HQAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHL 1080 Score = 27.3 bits (59), Expect = 4.8 Identities = 22/66 (33%), Positives = 24/66 (36%), Gaps = 12/66 (18%) Query: 37 GRGGDAFGDTSFLSRHGGGPPPEP---RAPPAG---------APRSPPPPAVPQSAAPSP 84 GR A +T L PP P A P G AP PPPP P + A P Sbjct: 996 GRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEP 1055 Query: 85 ADPLLS 90 L S Sbjct: 1056 KGGLTS 1061 Score = 26.9 bits (58), Expect = 6.2 Identities = 22/67 (32%), Positives = 26/67 (38%), Gaps = 18/67 (26%) Query: 66 GAPRSPPPPAVPQSAAPSPADPLLSFHLDLGPSMLDAVLGVMDAARPEAAAAKPDAEPRP 125 GAP+ PPPP P P P+ P L+A L + E AA P P Sbjct: 831 GAPQPPPPP-------PPPPPPM--------PLQLEAHL---RSHGLEPAAPSPRLRPEE 872 Query: 126 GTQPPQA 132 PP A Sbjct: 873 SLDPPGA 879 Score = 26.9 bits (58), Expect = 6.2 Identities = 20/76 (26%), Positives = 25/76 (32%), Gaps = 20/76 (26%) Query: 55 GPPPEPRAPPAGAPRSPPPPAVPQSAAPSPADPLLSFHLDLGPSMLDAVLGVMDAARPEA 114 GPP P A G P P P+ + P P PLL + P Sbjct: 1421 GPPLAPAAAVPGPPPLPGLPSANSNGTPEP--PLL------------------EEKPPPT 1460 Query: 115 AAAKPDAEPRPGTQPP 130 P +P+P PP Sbjct: 1461 PPPAPTPQPQPPPPPP 1476 >gi|126090663 zinc finger homeodomain 4 [Homo sapiens] Length = 3571 Score = 40.8 bits (94), Expect = 4e-04 Identities = 19/45 (42%), Positives = 23/45 (51%) Query: 56 PPPEPRAPPAGAPRSPPPPAVPQSAAPSPADPLLSFHLDLGPSML 100 PPP P PP P PPPP P +AP +S L L PS++ Sbjct: 1993 PPPTPPPPPPPPPPPPPPPPPPPPSAPPQVQLPVSLDLPLFPSIM 2037 Score = 34.7 bits (78), Expect = 0.030 Identities = 25/86 (29%), Positives = 31/86 (36%), Gaps = 2/86 (2%) Query: 57 PPEPRAPPAGAPRSPPPPAVPQSAAPSPADPLLSFHLDLGPSMLDAVLGVMDAARPEAAA 116 P P +P P PPPP P PS P+ + P L A P Sbjct: 1949 PISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTP--LQAPPPTPPPPPPPPPP 2006 Query: 117 AKPDAEPRPGTQPPQARCRPNADLEL 142 P P P + PPQ + + DL L Sbjct: 2007 PPPPPPPPPPSAPPQVQLPVSLDLPL 2032 Score = 32.7 bits (73), Expect = 0.11 Identities = 23/83 (27%), Positives = 35/83 (42%), Gaps = 10/83 (12%) Query: 56 PPPEPRAPPAGAPRSPPPPAVPQSAAPSPADPLLSFHLDLGPSMLDAVLGVMDAARPEAA 115 P P+P P +P+ P P+ + PSP L L + D P+A+ Sbjct: 2348 PSPKPE-PEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDP---------PQAS 2397 Query: 116 AAKPDAEPRPGTQPPQARCRPNA 138 A+P +P+P QP P+A Sbjct: 2398 TAQPQPQPQPPKQPQLIGRPPSA 2420 >gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo sapiens] Length = 247 Score = 40.8 bits (94), Expect = 4e-04 Identities = 34/126 (26%), Positives = 45/126 (35%), Gaps = 19/126 (15%) Query: 9 PAQPKKRPDRGALSISAPLGDFRHTLHVGRGGDAFGDTSFLSRHGGGPPPEPRAPP---A 65 P +P++ P +G P H G+ SR PP +P+ PP Sbjct: 138 PGKPERPPPQGGNQSQGP------PPHPGKPEGPPPQEGNKSRSARSPPGKPQGPPQQEG 191 Query: 66 GAPRSPPPPAVPQSAAPSPADPLLSFHLDLGPSMLDAVLGVMDAARPEAAAAKPDAEPRP 125 P+ PPPP PQ P+ +P P A G P +P P Sbjct: 192 NKPQGPPPPGKPQGPPPAGGNP-------QQPQAPPA--GKPQGPPPPPQGGRP-PRPAQ 241 Query: 126 GTQPPQ 131 G QPPQ Sbjct: 242 GQQPPQ 247 Score = 33.9 bits (76), Expect = 0.051 Identities = 15/34 (44%), Positives = 17/34 (50%) Query: 51 RHGGGPPPEPRAPPAGAPRSPPPPAVPQSAAPSP 84 R GG P+ PP G P+ PPP QS P P Sbjct: 40 RPQGGNQPQRPPPPPGKPQGPPPQGGNQSQGPPP 73 Score = 29.3 bits (64), Expect = 1.3 Identities = 25/89 (28%), Positives = 31/89 (34%), Gaps = 19/89 (21%) Query: 9 PAQPKKRPDRGALSISAPLGDFRHTLHVGR-------GGDAFGDTSFLSRHGGGPPPEPR 61 P +P+ RP +G P H G+ GG+ T PPP+ Sbjct: 75 PGKPEGRPPQGGNQSQGP------PPHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGG 128 Query: 62 ------APPAGAPRSPPPPAVPQSAAPSP 84 PP G P PPP QS P P Sbjct: 129 NQSHRPPPPPGKPERPPPQGGNQSQGPPP 157 Score = 28.1 bits (61), Expect = 2.8 Identities = 21/84 (25%), Positives = 26/84 (30%), Gaps = 7/84 (8%) Query: 55 GPPPEPRAPPAGAPRS-------PPPPAVPQSAAPSPADPLLSFHLDLGPSMLDAVLGVM 107 GPPP P P P+ PP P P+ P + G G Sbjct: 70 GPPPPPGKPEGRPPQGGNQSQGPPPHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGN 129 Query: 108 DAARPEAAAAKPDAEPRPGTQPPQ 131 + RP KP+ P G Q Sbjct: 130 QSHRPPPPPGKPERPPPQGGNQSQ 153 Score = 27.3 bits (59), Expect = 4.8 Identities = 14/36 (38%), Positives = 15/36 (41%), Gaps = 6/36 (16%) Query: 55 GPPPEPR------APPAGAPRSPPPPAVPQSAAPSP 84 GPPP+ PP G P PP QS P P Sbjct: 59 GPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPP 94 Score = 26.9 bits (58), Expect = 6.2 Identities = 13/27 (48%), Positives = 13/27 (48%), Gaps = 2/27 (7%) Query: 58 PEPRAPPAG--APRSPPPPAVPQSAAP 82 PE R P G R PPPP PQ P Sbjct: 36 PEGRRPQGGNQPQRPPPPPGKPQGPPP 62 >gi|149773456 hypothetical protein LOC643314 [Homo sapiens] Length = 1427 Score = 40.4 bits (93), Expect = 5e-04 Identities = 23/70 (32%), Positives = 34/70 (48%), Gaps = 2/70 (2%) Query: 56 PPPEPRAPPAGAPRSPPPPAVPQSAAPSPADPLLSFHLDLGPSMLDAVLGVMDAARPEAA 115 P PE A PA A +P PA P +A P+P +P +F P+ ++ + PE + Sbjct: 1112 PTPEEPASPAAAVPTPEEPASPAAAVPTPEEP--AFPAPAVPTPEESASAAVAVPTPEES 1169 Query: 116 AAKPDAEPRP 125 A+ A P P Sbjct: 1170 ASPAAAVPTP 1179 Score = 36.6 bits (83), Expect = 0.008 Identities = 23/75 (30%), Positives = 29/75 (38%), Gaps = 9/75 (12%) Query: 56 PPPEPRAPPAGAPRSPPPPAVPQSAAPSPADPLLSFHLDLGPSMLDAVLGVMDAARPEAA 115 PPPE PA A +P P P +A P+P +P S AV + P AA Sbjct: 1034 PPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEP---------TSPAAAVPTPEEPTSPAAA 1084 Query: 116 AAKPDAEPRPGTQPP 130 P+ P P Sbjct: 1085 VPTPEEPTSPAAAVP 1099 Score = 35.0 bits (79), Expect = 0.023 Identities = 23/75 (30%), Positives = 29/75 (38%), Gaps = 9/75 (12%) Query: 56 PPPEPRAPPAGAPRSPPPPAVPQSAAPSPADPLLSFHLDLGPSMLDAVLGVMDAARPEAA 115 P PE PA A +P P P +A P+P +P S AV + A P AA Sbjct: 1073 PTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEP---------TSPAAAVPTPEEPASPAAA 1123 Query: 116 AAKPDAEPRPGTQPP 130 P+ P P Sbjct: 1124 VPTPEEPASPAAAVP 1138 Score = 32.7 bits (73), Expect = 0.11 Identities = 22/73 (30%), Positives = 28/73 (38%), Gaps = 9/73 (12%) Query: 58 PEPRAPPAGAPRSPPPPAVPQSAAPSPADPLLSFHLDLGPSMLDAVLGVMDAARPEAAAA 117 PE A PA A +P P P +A P+P +P S AV + P AA Sbjct: 997 PEEPASPAAAVPTPEEPTSPAAAVPTPEEP---------TSPAAAVPPPEEPTSPAAAVP 1047 Query: 118 KPDAEPRPGTQPP 130 P+ P P Sbjct: 1048 TPEEPTSPAAAVP 1060 Score = 32.7 bits (73), Expect = 0.11 Identities = 22/75 (29%), Positives = 27/75 (36%), Gaps = 9/75 (12%) Query: 56 PPPEPRAPPAGAPRSPPPPAVPQSAAPSPADPLLSFHLDLGPSMLDAVLGVMDAARPEAA 115 P PE PA A +P P P +A P P +P S AV + P AA Sbjct: 1008 PTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEP---------TSPAAAVPTPEEPTSPAAA 1058 Query: 116 AAKPDAEPRPGTQPP 130 P+ P P Sbjct: 1059 VPTPEEPTSPAAAVP 1073 Score = 28.9 bits (63), Expect = 1.6 Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 3/60 (5%) Query: 56 PPPEPRAPPAGAPRSPPPPAVPQSAAPSP---ADPLLSFHLDLGPSMLDAVLGVMDAARP 112 P PE A PA A + PA P +A P+P A P S P++ A + M+ P Sbjct: 1275 PTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSP 1334 Score = 27.7 bits (60), Expect = 3.7 Identities = 21/71 (29%), Positives = 25/71 (35%), Gaps = 2/71 (2%) Query: 55 GPPPEPRAPPAG--APRSPPPPAVPQSAAPSPADPLLSFHLDLGPSMLDAVLGVMDAARP 112 G P P P AP P AV S PA P + P+ A + + Sbjct: 969 GTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTS 1028 Query: 113 EAAAAKPDAEP 123 AAA P EP Sbjct: 1029 PAAAVPPPEEP 1039 Score = 26.9 bits (58), Expect = 6.2 Identities = 13/31 (41%), Positives = 17/31 (54%) Query: 56 PPPEPRAPPAGAPRSPPPPAVPQSAAPSPAD 86 P PE A A A +P A P +A P+PA+ Sbjct: 1151 PTPEESASAAVAVPTPEESASPAAAVPTPAE 1181 Score = 26.6 bits (57), Expect = 8.2 Identities = 22/76 (28%), Positives = 28/76 (36%), Gaps = 14/76 (18%) Query: 57 PPEPRAPPAGAP--RSPPPPAVPQSAAPSPADPLLSFHLDLGPSMLDAVLGVMDAARPEA 114 P EP +P A P P PA +A P+P +P S AV + P A Sbjct: 1023 PEEPTSPAAAVPPPEEPTSPA---AAVPTPEEP---------TSPAAAVPTPEEPTSPAA 1070 Query: 115 AAAKPDAEPRPGTQPP 130 A P+ P P Sbjct: 1071 AVPTPEEPTSPAAAVP 1086 Score = 26.6 bits (57), Expect = 8.2 Identities = 22/76 (28%), Positives = 28/76 (36%), Gaps = 14/76 (18%) Query: 57 PPEPRAPPAGAP--RSPPPPAVPQSAAPSPADPLLSFHLDLGPSMLDAVLGVMDAARPEA 114 P EP +P A P P PA +A P+P +P S AV + P A Sbjct: 1049 PEEPTSPAAAVPTPEEPTSPA---AAVPTPEEP---------TSPAAAVPTPEEPTSPAA 1096 Query: 115 AAAKPDAEPRPGTQPP 130 A P+ P P Sbjct: 1097 AVPTPEEPTSPAAAVP 1112 >gi|52485606 formin-like 2 [Homo sapiens] Length = 1092 Score = 40.4 bits (93), Expect = 5e-04 Identities = 31/105 (29%), Positives = 36/105 (34%), Gaps = 26/105 (24%) Query: 40 GDAFGDTSFLSRHGGGPPPEPRAPPAG--------------APRSPPPPAVPQSAAPSPA 85 G++ G T + G PPP P PP+ P PPPP P P P Sbjct: 511 GNSVGPTMGAASSGPLPPPPPPLPPSSDTPETVQNGPVTPPMPPPPPPPPPPPPPPPPPP 570 Query: 86 DPLLSFHLDLGPSMLDAVLGVMDAARPEAAAAKPDAEPRPGTQPP 130 P L GP+ P A P A P PGT P Sbjct: 571 PPPLP-----GPA-------AETVPAPPLAPPLPSAPPLPGTSSP 603 >gi|122937496 WAS/WASL interacting protein family, member 3 [Homo sapiens] Length = 483 Score = 39.7 bits (91), Expect = 0.001 Identities = 39/126 (30%), Positives = 44/126 (34%), Gaps = 17/126 (13%) Query: 8 GPAQPKKRPDRGALSISAPLGDFRHTLHVGRGGDAFGDTSFLSRHGGGPPPEPR--APPA 65 GP P +IS PL + G+TS PP P APP Sbjct: 125 GPGSRAPSPRLPNKTISGPL--------IPPASPRLGNTSEAHGAARTAPPRPNVPAPPP 176 Query: 66 GAPRSPPPPAVPQSAAPSP-ADPLLSFHLDLGPSMLDAVLGVMDAARPEAAAAKPDAEPR 124 P PPPP P + SP PL+S L L V A P A P P Sbjct: 177 PTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVV------APPVPCAPPPPPPPP 230 Query: 125 PGTQPP 130 P T PP Sbjct: 231 PPTPPP 236 Score = 38.1 bits (87), Expect = 0.003 Identities = 30/91 (32%), Positives = 34/91 (37%), Gaps = 11/91 (12%) Query: 56 PPPEPRAPPAGAPRSPPPPAVPQSAAPSPADPLLSFHLDLGPSMLDAVLGV------MDA 109 PPP P PP P PP + A PL HL P L + + Sbjct: 223 PPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPL---HLPPIPPPLPLLPPCGYPGLKAEP 279 Query: 110 ARPEAAAAKPDAEPRPGTQPPQARCRPNADL 140 A P A +P A P P PP A C P A L Sbjct: 280 ASPAQDAQEPPAPPPP--LPPYASCSPRASL 308 Score = 33.5 bits (75), Expect = 0.067 Identities = 18/35 (51%), Positives = 18/35 (51%), Gaps = 3/35 (8%) Query: 56 PPPEPRAPPAGAPRSPPPPAVPQSAAPSP---ADP 87 PP P PP GAP PPP A P S S ADP Sbjct: 9 PPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADP 43 Score = 31.6 bits (70), Expect = 0.25 Identities = 24/96 (25%), Positives = 35/96 (36%), Gaps = 22/96 (22%) Query: 56 PPPEPRAPPAG----------------APRSPPPP------AVPQSAAPSPADPLLSFHL 93 PPP P PP G P +PPPP P+++ P+P P ++ Sbjct: 261 PPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSS 320 Query: 94 DLGPSMLDAVLGVMDAARPEAAAAKPDAEPRPGTQP 129 + P + + A A P PG+QP Sbjct: 321 ETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQP 356 Score = 27.7 bits (60), Expect = 3.7 Identities = 12/31 (38%), Positives = 15/31 (48%) Query: 60 PRAPPAGAPRSPPPPAVPQSAAPSPADPLLS 90 P PP P PPPP + P P+ P +S Sbjct: 2 PVPPPPPPPLPPPPPPLGAPPPPPPSAPPVS 32 >gi|122937267 lemur tyrosine kinase 3 [Homo sapiens] Length = 1489 Score = 39.7 bits (91), Expect = 0.001 Identities = 30/81 (37%), Positives = 35/81 (43%), Gaps = 5/81 (6%) Query: 53 GGGPPPEPRAPPAGAPRSPPPPAV---PQSAAPSPADPLLSFHLDLGPSMLDAVLGVM-D 108 G GPPP P PP PR+P PA P SA SP L S G S + + Sbjct: 775 GRGPPPAPPPPPP-PPRAPADPAASPDPPSAVASPGSGLSSPGPKPGDSGYETETPFSPE 833 Query: 109 AARPEAAAAKPDAEPRPGTQP 129 A P AA+ + PRP P Sbjct: 834 GAFPGGGAAEEEGVPRPRAPP 854 Score = 31.6 bits (70), Expect = 0.25 Identities = 22/76 (28%), Positives = 31/76 (40%), Gaps = 3/76 (3%) Query: 63 PPAGAPRSPPPPAVPQSAAPSPADPLLSFHLDLGPSMLDAVLGVMDAARPEAAAAKPDAE 122 P G P P + ++ S AD ++ P LD ++G AA P+ P Sbjct: 725 PALGCPHPPEDDSSLRAERGSLADLPMAPPASAPPEFLDPLMG---AAAPQYPGRGPPPA 781 Query: 123 PRPGTQPPQARCRPNA 138 P P PP+A P A Sbjct: 782 PPPPPPPPRAPADPAA 797 Score = 30.8 bits (68), Expect = 0.43 Identities = 36/137 (26%), Positives = 50/137 (36%), Gaps = 23/137 (16%) Query: 7 LGPAQPKKRPDRGALSISAPLGDFRHTLHVGRGGDAFGDTSFLSRHGGGPPP-------- 58 L P ++ P+ G AP L +G GG A T + GGGP Sbjct: 1113 LEPGTERRAPETGG----APRAPGAGRLDLGSGGRAPVGTG--TAPGGGPGSGVDAKAGW 1166 Query: 59 ----EPRAPPAGAPRSPPPPAVPQSAAPSPADPLLSFHLDLGPSMLDAVLGVMDAARPEA 114 P+ PP P PPP A P+ P+P + P D+ G A + Sbjct: 1167 VDNTRPQPPPPPLP--PPPEAQPRRLEPAPPRARPEVAPEGEPGAPDSRAGGDTALSGDG 1224 Query: 115 AAAKPDAEPRPGTQPPQ 131 KP+ R G + P+ Sbjct: 1225 DPPKPE---RKGPEMPR 1238 Score = 28.9 bits (63), Expect = 1.6 Identities = 22/64 (34%), Positives = 23/64 (35%), Gaps = 18/64 (28%) Query: 45 DTSFLSRHGGGPPPEPRAPPAGAP-----------------RSPPPPAVPQSAAP-SPAD 86 D S L G P APPA AP R PPP P P +PAD Sbjct: 735 DDSSLRAERGSLADLPMAPPASAPPEFLDPLMGAAAPQYPGRGPPPAPPPPPPPPRAPAD 794 Query: 87 PLLS 90 P S Sbjct: 795 PAAS 798 Score = 28.5 bits (62), Expect = 2.1 Identities = 13/21 (61%), Positives = 13/21 (61%), Gaps = 4/21 (19%) Query: 58 PEPRAPP----AGAPRSPPPP 74 P PRAPP GAPR PP P Sbjct: 848 PRPRAPPEPPDPGAPRPPPDP 868 Score = 27.7 bits (60), Expect = 3.7 Identities = 30/106 (28%), Positives = 38/106 (35%), Gaps = 17/106 (16%) Query: 46 TSFLSRHGGGPPPEPRAPPAGAPRSPPPPA--VPQSAAPSPADPLLSFHLDLGPSMLDAV 103 T LS PPP P P G P PPA P+ S PLL P D V Sbjct: 438 TYLLSERPPRPPPPPPPPRDGPFPWPWPPAHSAPRPGTLSSPFPLLDGFPGADP---DDV 494 Query: 104 LGVMDAAR----------PEAAAAKPDAEP--RPGTQPPQARCRPN 137 L V +++R A + P +P + PP P+ Sbjct: 495 LTVTESSRGLNLECLWEKARRGAGRGGGAPAWQPASAPPAPHANPS 540 Score = 27.7 bits (60), Expect = 3.7 Identities = 15/36 (41%), Positives = 16/36 (44%) Query: 55 GPPPEPRAPPAGAPRSPPPPAVPQSAAPSPADPLLS 90 G PPEP P P P PA APS L+S Sbjct: 575 GSPPEPLFPNDWDPLDPGVPAPQAPQAPSEVPQLVS 610 Score = 27.3 bits (59), Expect = 4.8 Identities = 14/35 (40%), Positives = 15/35 (42%), Gaps = 4/35 (11%) Query: 53 GGGPPPEPRAPPAGAPRSPPPPAVPQSAAPSPADP 87 GGG E P AP PP P P+ P DP Sbjct: 838 GGGAAEEEGVPRPRAPPEPPDPGAPR----PPPDP 868 Score = 26.9 bits (58), Expect = 6.2 Identities = 15/31 (48%), Positives = 16/31 (51%), Gaps = 6/31 (19%) Query: 57 PPE----PRAPPAGAPRSPPPPAVPQSAAPS 83 PPE P PPA P +PP PA P PS Sbjct: 1405 PPEGDTDPSTPPA--PPTPPHPATPGDGFPS 1433 >gi|115334682 SNAP25-interacting protein [Homo sapiens] Length = 1183 Score = 39.7 bits (91), Expect = 0.001 Identities = 38/115 (33%), Positives = 50/115 (43%), Gaps = 17/115 (14%) Query: 22 SISAPLGDFRHTLH--VGRGGDAFGDTSFLSRHGGG---PPPEPR--APPAGAPRSPPPP 74 S +A D +L+ G GG +GD G G PP P+ A A P PPPP Sbjct: 439 SAAALQSDLEDSLYKAAGGGGPLYGD-------GYGFRLPPSSPQKLADVAAPPGGPPPP 491 Query: 75 AVPQSAAPSPADPL-LSFHLDLGPSML--DAVLGVMDAARPEAAAAKPDAEPRPG 126 P S PS P+ SF D G S + ++ G +A + A P +E PG Sbjct: 492 HSPYSGPPSRGSPVRQSFRKDSGSSSVFAESPGGKTRSAGSASTAGAPPSELFPG 546 >gi|124107614 PR domain containing 13 [Homo sapiens] Length = 707 Score = 39.7 bits (91), Expect = 0.001 Identities = 36/114 (31%), Positives = 51/114 (44%), Gaps = 12/114 (10%) Query: 32 HTLHVGRGGDAFGDTSFLSRHGGGPPPEPRAPPAGAPRSPPPPAVPQSAAPSPADPLLSF 91 H + G GG AF +R G P + G SP PPA P AAPS A L Sbjct: 159 HCVFSGGGGGAFLHHEHAARQGAVPAAD------GLGLSPKPPA-PDFAAPSQAGTLRPH 211 Query: 92 HLDLGPSMLDAVLGVMDAARPEAAAAKPDAEPRPGT--QPPQARCRPNADLELN 143 LGP + A G + + EA++A P PG QP + + + + L+++ Sbjct: 212 --PLGPPPVQA-CGAREGIKREASSAPSATSPTPGKWGQPKKGKEQLDRALDMS 262 Score = 34.3 bits (77), Expect = 0.039 Identities = 44/133 (33%), Positives = 52/133 (39%), Gaps = 16/133 (12%) Query: 9 PAQPKKRPDRGA-LSISAPLGDFRHTLHVGRG-GDAFGDTSFLSRHGGGPPPEPRAPPAG 66 P + + +GA L++ LG R G G A G H P+ AG Sbjct: 311 PYREESSSKQGAGLALGRLLGGGRACGRPGSGENSAAGGAGHHHHHHAHHHHHPKCLLAG 370 Query: 67 APRSPPPPAVPQSAAPSPADPLLSFHLDLGPSMLDAVLGVMDAARPEAAAAKPDAE---- 122 P PPPP +P S A PLLS + P A V A P AAAA P A Sbjct: 371 DPPPPPPPGLPCSGA-LRGFPLLS----VPPEEASAFKHVERA--PPAAAALPGARYAQL 423 Query: 123 -PRPGTQPPQARC 134 P PG P RC Sbjct: 424 PPAPGL--PLERC 434 >gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] Length = 502 Score = 39.3 bits (90), Expect = 0.001 Identities = 22/53 (41%), Positives = 23/53 (43%) Query: 37 GRGGDAFGDTSFLSRHGGGPPPEPRAPPAGAPRSPPPPAVPQSAAPSPADPLL 89 GRGG R G PPP P A P PPPP P S+ PA P L Sbjct: 363 GRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPL 415 Score = 36.6 bits (83), Expect = 0.008 Identities = 17/35 (48%), Positives = 18/35 (51%), Gaps = 3/35 (8%) Query: 56 PPPEPRAPP---AGAPRSPPPPAVPQSAAPSPADP 87 PPP PR PP G P PPPPA +S P P Sbjct: 352 PPPTPRGPPPPGRGGPPPPPPPATGRSGPLPPPPP 386 Score = 32.7 bits (73), Expect = 0.11 Identities = 30/98 (30%), Positives = 34/98 (34%), Gaps = 21/98 (21%) Query: 38 RGGDAFGDTSFLSRHGG--GP-PPEPR--APPAGAPRSPPPPAVPQSAAPSPADPLLSFH 92 RGG+ + + G GP PP P APP PR PPPP + P P P Sbjct: 321 RGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPPPG--RGGPPPPPPPATGRS 378 Query: 93 LDLGPSMLDAVLGVMDAARPEAAAAKPDAEPRPGTQPP 130 L P P A P P P PP Sbjct: 379 GPLPP--------------PPPGAGGPPMPPPPPPPPP 402 Score = 31.6 bits (70), Expect = 0.25 Identities = 11/28 (39%), Positives = 15/28 (53%) Query: 56 PPPEPRAPPAGAPRSPPPPAVPQSAAPS 83 PPP P PP + P PP +P + P+ Sbjct: 395 PPPPPPPPPPSSGNGPAPPPLPPALVPA 422 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.315 0.137 0.428 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,520,114 Number of Sequences: 37866 Number of extensions: 675249 Number of successful extensions: 18092 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 907 Number of HSP's successfully gapped in prelim test: 1005 Number of HSP's that attempted gapping in prelim test: 6737 Number of HSP's gapped (non-prelim): 7921 length of query: 148 length of database: 18,247,518 effective HSP length: 93 effective length of query: 55 effective length of database: 14,725,980 effective search space: 809928900 effective search space used: 809928900 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 57 (26.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.