Search of human proteins with 29826319

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|29826319 adducin 1 (alpha) isoform a [Homo sapiens]
         (737 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|29826319 adducin 1 (alpha) isoform a [Homo sapiens]               1483   0.0  
gi|29826321 adducin 1 (alpha) isoform b [Homo sapiens]               1467   0.0  
gi|29826323 adducin 1 (alpha) isoform c [Homo sapiens]               1247   0.0  
gi|29826325 adducin 1 (alpha) isoform d [Homo sapiens]               1231   0.0  
gi|9943848 adducin 3 (gamma) isoform a [Homo sapiens]                 694   0.0  
gi|9951927 adducin 3 (gamma) isoform b [Homo sapiens]                 672   0.0  
gi|62912453 adducin 3 (gamma) isoform b [Homo sapiens]                672   0.0  
gi|9257192 adducin 2 isoform a [Homo sapiens]                         633   0.0  
gi|9257190 adducin 2 isoform e [Homo sapiens]                         589   e-168
gi|89276787 adducin 2 isoform b [Homo sapiens]                        555   e-158
gi|89276790 adducin 2 isoform d [Homo sapiens]                        208   1e-53
gi|9257180 adducin 2 isoform c [Homo sapiens]                         208   1e-53
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     59   2e-08
gi|30795231 brain abundant, membrane attached signal protein 1 [...    54   4e-07
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]             51   3e-06
gi|110349717 titin isoform novex-2 [Homo sapiens]                      51   4e-06
gi|110349713 titin isoform novex-1 [Homo sapiens]                      51   4e-06
gi|110349715 titin isoform N2-B [Homo sapiens]                         51   4e-06
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        50   6e-06
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap...    50   8e-06
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap...    50   8e-06
gi|62000702 diacylglycerol kinase kappa [Homo sapiens]                 50   8e-06
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    48   3e-05
gi|112734870 hypothetical protein LOC57648 [Homo sapiens]              47   5e-05
gi|110349719 titin isoform N2-A [Homo sapiens]                         47   6e-05
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   47   6e-05
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   47   6e-05
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   47   6e-05
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    47   6e-05
gi|153792074 proline rich 12 [Homo sapiens]                            47   6e-05

>gi|29826319 adducin 1 (alpha) isoform a [Homo sapiens]
          Length = 737

 Score = 1483 bits (3839), Expect = 0.0
 Identities = 737/737 (100%), Positives = 737/737 (100%)

Query: 1   MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM 60
           MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM
Sbjct: 1   MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM 60

Query: 61  ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS 120
           ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS
Sbjct: 61  ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS 120

Query: 121 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF 180
           LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF
Sbjct: 121 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF 180

Query: 181 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI 240
           LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI
Sbjct: 181 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI 240

Query: 241 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR 300
           HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR
Sbjct: 241 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR 300

Query: 301 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV 360
           NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV
Sbjct: 301 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV 360

Query: 361 GEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYS 420
           GEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYS
Sbjct: 361 GEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYS 420

Query: 421 FASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTKWTKEDGHRT 480
           FASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTKWTKEDGHRT
Sbjct: 421 FASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTKWTKEDGHRT 480

Query: 481 STSAVPNLFVPLNTNPKEVQEMRNKIREQNLQDIKTAGPQSQVLCGVVMDRSLVQGELVT 540
           STSAVPNLFVPLNTNPKEVQEMRNKIREQNLQDIKTAGPQSQVLCGVVMDRSLVQGELVT
Sbjct: 481 STSAVPNLFVPLNTNPKEVQEMRNKIREQNLQDIKTAGPQSQVLCGVVMDRSLVQGELVT 540

Query: 541 ASKAIIEKEYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKS 600
           ASKAIIEKEYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKS
Sbjct: 541 ASKAIIEKEYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKS 600

Query: 601 PPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEK 660
           PPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEK
Sbjct: 601 PPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEK 660

Query: 661 EEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKKKK 720
           EEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKKKK
Sbjct: 661 EEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKKKK 720

Query: 721 KFRTPSFLKKSKKKSDS 737
           KFRTPSFLKKSKKKSDS
Sbjct: 721 KFRTPSFLKKSKKKSDS 737


>gi|29826321 adducin 1 (alpha) isoform b [Homo sapiens]
          Length = 768

 Score = 1467 bits (3797), Expect = 0.0
 Identities = 737/768 (95%), Positives = 737/768 (95%), Gaps = 31/768 (4%)

Query: 1   MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM 60
           MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM
Sbjct: 1   MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM 60

Query: 61  ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS 120
           ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS
Sbjct: 61  ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS 120

Query: 121 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF 180
           LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF
Sbjct: 121 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF 180

Query: 181 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI 240
           LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI
Sbjct: 181 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI 240

Query: 241 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR 300
           HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR
Sbjct: 241 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR 300

Query: 301 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV 360
           NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV
Sbjct: 301 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV 360

Query: 361 GEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYS 420
           GEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYS
Sbjct: 361 GEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYS 420

Query: 421 FASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTK--------- 471
           FASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTK         
Sbjct: 421 FASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTKVWTNITHDH 480

Query: 472 ----------------------WTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQ 509
                                 WTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQ
Sbjct: 481 VKPLLQSLSSGVCVPSCITNCLWTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQ 540

Query: 510 NLQDIKTAGPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTTLTD 569
           NLQDIKTAGPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTTLTD
Sbjct: 541 NLQDIKTAGPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTTLTD 600

Query: 570 RELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTG 629
           RELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTG
Sbjct: 601 RELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTG 660

Query: 630 DDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVA 689
           DDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVA
Sbjct: 661 DDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVA 720

Query: 690 EEAAPSAVEEGAAADPGSDGSPGKSPSKKKKKFRTPSFLKKSKKKSDS 737
           EEAAPSAVEEGAAADPGSDGSPGKSPSKKKKKFRTPSFLKKSKKKSDS
Sbjct: 721 EEAAPSAVEEGAAADPGSDGSPGKSPSKKKKKFRTPSFLKKSKKKSDS 768


>gi|29826323 adducin 1 (alpha) isoform c [Homo sapiens]
          Length = 631

 Score = 1247 bits (3227), Expect = 0.0
 Identities = 620/620 (100%), Positives = 620/620 (100%)

Query: 1   MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM 60
           MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM
Sbjct: 1   MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM 60

Query: 61  ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS 120
           ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS
Sbjct: 61  ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS 120

Query: 121 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF 180
           LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF
Sbjct: 121 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF 180

Query: 181 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI 240
           LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI
Sbjct: 181 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI 240

Query: 241 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR 300
           HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR
Sbjct: 241 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR 300

Query: 301 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV 360
           NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV
Sbjct: 301 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV 360

Query: 361 GEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYS 420
           GEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYS
Sbjct: 361 GEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYS 420

Query: 421 FASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTKWTKEDGHRT 480
           FASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTKWTKEDGHRT
Sbjct: 421 FASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTKWTKEDGHRT 480

Query: 481 STSAVPNLFVPLNTNPKEVQEMRNKIREQNLQDIKTAGPQSQVLCGVVMDRSLVQGELVT 540
           STSAVPNLFVPLNTNPKEVQEMRNKIREQNLQDIKTAGPQSQVLCGVVMDRSLVQGELVT
Sbjct: 481 STSAVPNLFVPLNTNPKEVQEMRNKIREQNLQDIKTAGPQSQVLCGVVMDRSLVQGELVT 540

Query: 541 ASKAIIEKEYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKS 600
           ASKAIIEKEYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKS
Sbjct: 541 ASKAIIEKEYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKS 600

Query: 601 PPDQPAVPHPPPSTPIKLEE 620
           PPDQPAVPHPPPSTPIKLEE
Sbjct: 601 PPDQPAVPHPPPSTPIKLEE 620


>gi|29826325 adducin 1 (alpha) isoform d [Homo sapiens]
          Length = 662

 Score = 1231 bits (3185), Expect = 0.0
 Identities = 620/651 (95%), Positives = 620/651 (95%), Gaps = 31/651 (4%)

Query: 1   MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM 60
           MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM
Sbjct: 1   MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM 60

Query: 61  ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS 120
           ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS
Sbjct: 61  ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS 120

Query: 121 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF 180
           LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF
Sbjct: 121 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF 180

Query: 181 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI 240
           LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI
Sbjct: 181 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI 240

Query: 241 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR 300
           HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR
Sbjct: 241 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR 300

Query: 301 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV 360
           NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV
Sbjct: 301 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV 360

Query: 361 GEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYS 420
           GEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYS
Sbjct: 361 GEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYS 420

Query: 421 FASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTK--------- 471
           FASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTK         
Sbjct: 421 FASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTKVWTNITHDH 480

Query: 472 ----------------------WTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQ 509
                                 WTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQ
Sbjct: 481 VKPLLQSLSSGVCVPSCITNCLWTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQ 540

Query: 510 NLQDIKTAGPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTTLTD 569
           NLQDIKTAGPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTTLTD
Sbjct: 541 NLQDIKTAGPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTTLTD 600

Query: 570 RELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEE 620
           RELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEE
Sbjct: 601 RELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEE 651


>gi|9943848 adducin 3 (gamma) isoform a [Homo sapiens]
          Length = 706

 Score =  694 bits (1791), Expect = 0.0
 Identities = 384/750 (51%), Positives = 502/750 (66%), Gaps = 65/750 (8%)

Query: 1   MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM 60
           M+ D+   V+T+PPP + PHKERYFDR++EN+PEY+RERNM+PDLRQDFNMMEQ+KRV+ 
Sbjct: 1   MSSDASQGVITTPPPPSMPHKERYFDRINENDPEYIRERNMSPDLRQDFNMMEQRKRVTQ 60

Query: 61  ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS 120
           ILQSPAF E+LE +IQEQ KKG NPTGLLALQQIAD++  N  + + + P        +S
Sbjct: 61  ILQSPAFREDLECLIQEQMKKGHNPTGLLALQQIADYIMANSFSGFSSPP--------LS 112

Query: 121 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF 180
           LGMVTP+NDL G+D+ +Y KGEKL RCKLA+ YRL DLFGW+ L   +I+ R++ EQ+H 
Sbjct: 113 LGMVTPINDLPGADTSSYVKGEKLTRCKLASLYRLVDLFGWAHLANTYISVRISKEQDHI 172

Query: 181 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI 240
           +I+P GL +SE TAS+LVK+N+ G++VD+GSTNL ++  GF+ H+AIY+ RPDVKCV+HI
Sbjct: 173 IIIPRGLSFSEATASNLVKVNIIGEVVDQGSTNLKIDHTGFSPHAAIYSTRPDVKCVIHI 232

Query: 241 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR 300
           HT A AAVS+MKCG+LPIS E+L LG+VAY+DY G L ++EE++ +QK LGP  KVL+LR
Sbjct: 233 HTLATAAVSSMKCGILPISQESLLLGDVAYYDYQGSLEEQEERIQLQKVLGPSCKVLVLR 292

Query: 301 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV 360
           NHG+V++GE++EEAF+YI N+ +ACEIQV+ LA AGG DNL +L+ +KYKA + +  +  
Sbjct: 293 NHGVVALGETLEEAFHYIFNVQLACEIQVQALAGAGGVDNLHVLDFQKYKAFTYTVAASG 352

Query: 361 GEGT--GSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTG 418
           G G   GS  KW++GE EFE LMR LDNLGYRTGY YR+P +REK +  SDVE+PA+VT 
Sbjct: 353 GGGVNMGSHQKWKVGEIEFEGLMRTLDNLGYRTGYAYRHPLIREKPRHKSDVEIPATVTA 412

Query: 419 YSFASDGDSGTCSPLRHSFQKQQREKTRWLNSGR---GDEASEEGQNG-SSPKSKTKWTK 474
           +SF  + D+   SPL++  Q+QQREKTRWLNS          EE +NG +SP++K  W K
Sbjct: 413 FSF--EDDTVPLSPLKYMAQRQQREKTRWLNSPNTYMKVNVPEESRNGETSPRTKITWMK 470

Query: 475 -EDGHRTSTSAV-----PNLFVPLNTNPKEVQEMRNKIREQNLQDIKTAGPQSQVLCGVV 528
            ED  + S         PN FVPLNTNP EV E RNKIREQN  D+KTAGPQSQ+L G+V
Sbjct: 471 AEDSSKVSGGTPIKIEDPNQFVPLNTNPNEVLEKRNKIREQNRYDLKTAGPQSQLLAGIV 530

Query: 529 MDR--SLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGS 586
           +D+  S +Q E         + ++ P        PNPF+ LT+ ELEEY+R +ERKQ+G 
Sbjct: 531 VDKPPSTMQFE---------DDDHGP-----PAPPNPFSHLTEGELEEYKRTIERKQQGL 576

Query: 587 EENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSP 646
           E+   E       S     +    P + P KLEE+          S  +   P +     
Sbjct: 577 EDAEQELLSDDASSVSQIQSQTQSPQNVPEKLEEN----HELFSKSFISMEVPVMVVNGK 632

Query: 647 DEPSEALGFPMLEKEEEAHRPPS--PTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAAD 704
           D+        M + E+E  +  S   T    E        P  + E  +P          
Sbjct: 633 DD--------MHDVEDELAKRVSRLSTSTTIENIEITIKSPEKIEEVLSP---------- 674

Query: 705 PGSDGSPGKSPSKKKKKFRTPSFLKKSKKK 734
              +GSP KSPSKKKKKFRTPSFLKK+KKK
Sbjct: 675 ---EGSPSKSPSKKKKKFRTPSFLKKNKKK 701


>gi|9951927 adducin 3 (gamma) isoform b [Homo sapiens]
          Length = 674

 Score =  672 bits (1733), Expect = 0.0
 Identities = 377/748 (50%), Positives = 493/748 (65%), Gaps = 93/748 (12%)

Query: 1   MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM 60
           M+ D+   V+T+PPP + PHKERYFDR++EN+PEY+RERNM+PDLRQDFNMMEQ+KRV+ 
Sbjct: 1   MSSDASQGVITTPPPPSMPHKERYFDRINENDPEYIRERNMSPDLRQDFNMMEQRKRVTQ 60

Query: 61  ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS 120
           ILQSPAF E+LE +IQEQ KKG NPTGLLALQQIAD++  N  + + + P        +S
Sbjct: 61  ILQSPAFREDLECLIQEQMKKGHNPTGLLALQQIADYIMANSFSGFSSPP--------LS 112

Query: 121 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF 180
           LGMVTP+NDL G+D+ +Y KGEKL RCKLA+ YRL DLFGW+ L   +I+ R++ EQ+H 
Sbjct: 113 LGMVTPINDLPGADTSSYVKGEKLTRCKLASLYRLVDLFGWAHLANTYISVRISKEQDHI 172

Query: 181 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI 240
           +I+P GL +SE TAS+LVK+N+ G++VD+GSTNL ++  GF+ H+AIY+ RPDVKCV+HI
Sbjct: 173 IIIPRGLSFSEATASNLVKVNIIGEVVDQGSTNLKIDHTGFSPHAAIYSTRPDVKCVIHI 232

Query: 241 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR 300
           HT A AAVS+MKCG+LPIS E+L LG+VAY+DY G L ++EE++ +QK LGP  KVL+LR
Sbjct: 233 HTLATAAVSSMKCGILPISQESLLLGDVAYYDYQGSLEEQEERIQLQKVLGPSCKVLVLR 292

Query: 301 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV 360
           NHG+V++GE++EEAF+YI N+ +ACEIQV+ LA AGG DNL +L+ +KYKA + +  +  
Sbjct: 293 NHGVVALGETLEEAFHYIFNVQLACEIQVQALAGAGGVDNLHVLDFQKYKAFTYTVAASG 352

Query: 361 GEGT--GSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTG 418
           G G   GS  KW++GE EFE LMR LDNLGYRTGY YR+P +REK +  SDVE+PA+VT 
Sbjct: 353 GGGVNMGSHQKWKVGEIEFEGLMRTLDNLGYRTGYAYRHPLIREKPRHKSDVEIPATVTA 412

Query: 419 YSFASDGDSGTCSPLRHSFQKQQREKTRWLNSGR---GDEASEEGQNG-SSPKSKTKWTK 474
           +SF  + D+   SPL++  Q+QQREKTRWLNS          EE +NG +SP++K  W K
Sbjct: 413 FSF--EDDTVPLSPLKYMAQRQQREKTRWLNSPNTYMKVNVPEESRNGETSPRTKITWMK 470

Query: 475 -EDGHRTSTSAV-----PNLFVPLNTNPKEVQEMRNKIREQNLQDIKTAGPQSQVLCGVV 528
            ED  + S         PN FVPLNTNP EV E RNKIREQN  D+KTAGPQSQ+L G+V
Sbjct: 471 AEDSSKVSGGTPIKIEDPNQFVPLNTNPNEVLEKRNKIREQNRYDLKTAGPQSQLLAGIV 530

Query: 529 MDR--SLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGS 586
           +D+  S +Q E         + ++ P        PNPF+ LT+ ELEEY+R +ERKQ+G 
Sbjct: 531 VDKPPSTMQFE---------DDDHGP-----PAPPNPFSHLTEGELEEYKRTIERKQQGL 576

Query: 587 EENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSP 646
           EEN     E   KS      +    P   +  ++D+       D  D    + +    S 
Sbjct: 577 EEN----HELFSKS-----FISMEVPVMVVNGKDDM------HDVEDELAKRVSRLSTST 621

Query: 647 DEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPG 706
              +  +     EK EE              SPE +P  +P                   
Sbjct: 622 TIENIEITIKSPEKIEEV------------LSPEGSPSKSP------------------- 650

Query: 707 SDGSPGKSPSKKKKKFRTPSFLKKSKKK 734
                    SKKKKKFRTPSFLKK+KKK
Sbjct: 651 ---------SKKKKKFRTPSFLKKNKKK 669


>gi|62912453 adducin 3 (gamma) isoform b [Homo sapiens]
          Length = 674

 Score =  672 bits (1733), Expect = 0.0
 Identities = 377/748 (50%), Positives = 493/748 (65%), Gaps = 93/748 (12%)

Query: 1   MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM 60
           M+ D+   V+T+PPP + PHKERYFDR++EN+PEY+RERNM+PDLRQDFNMMEQ+KRV+ 
Sbjct: 1   MSSDASQGVITTPPPPSMPHKERYFDRINENDPEYIRERNMSPDLRQDFNMMEQRKRVTQ 60

Query: 61  ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS 120
           ILQSPAF E+LE +IQEQ KKG NPTGLLALQQIAD++  N  + + + P        +S
Sbjct: 61  ILQSPAFREDLECLIQEQMKKGHNPTGLLALQQIADYIMANSFSGFSSPP--------LS 112

Query: 121 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF 180
           LGMVTP+NDL G+D+ +Y KGEKL RCKLA+ YRL DLFGW+ L   +I+ R++ EQ+H 
Sbjct: 113 LGMVTPINDLPGADTSSYVKGEKLTRCKLASLYRLVDLFGWAHLANTYISVRISKEQDHI 172

Query: 181 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI 240
           +I+P GL +SE TAS+LVK+N+ G++VD+GSTNL ++  GF+ H+AIY+ RPDVKCV+HI
Sbjct: 173 IIIPRGLSFSEATASNLVKVNIIGEVVDQGSTNLKIDHTGFSPHAAIYSTRPDVKCVIHI 232

Query: 241 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR 300
           HT A AAVS+MKCG+LPIS E+L LG+VAY+DY G L ++EE++ +QK LGP  KVL+LR
Sbjct: 233 HTLATAAVSSMKCGILPISQESLLLGDVAYYDYQGSLEEQEERIQLQKVLGPSCKVLVLR 292

Query: 301 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV 360
           NHG+V++GE++EEAF+YI N+ +ACEIQV+ LA AGG DNL +L+ +KYKA + +  +  
Sbjct: 293 NHGVVALGETLEEAFHYIFNVQLACEIQVQALAGAGGVDNLHVLDFQKYKAFTYTVAASG 352

Query: 361 GEGT--GSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTG 418
           G G   GS  KW++GE EFE LMR LDNLGYRTGY YR+P +REK +  SDVE+PA+VT 
Sbjct: 353 GGGVNMGSHQKWKVGEIEFEGLMRTLDNLGYRTGYAYRHPLIREKPRHKSDVEIPATVTA 412

Query: 419 YSFASDGDSGTCSPLRHSFQKQQREKTRWLNSGR---GDEASEEGQNG-SSPKSKTKWTK 474
           +SF  + D+   SPL++  Q+QQREKTRWLNS          EE +NG +SP++K  W K
Sbjct: 413 FSF--EDDTVPLSPLKYMAQRQQREKTRWLNSPNTYMKVNVPEESRNGETSPRTKITWMK 470

Query: 475 -EDGHRTSTSAV-----PNLFVPLNTNPKEVQEMRNKIREQNLQDIKTAGPQSQVLCGVV 528
            ED  + S         PN FVPLNTNP EV E RNKIREQN  D+KTAGPQSQ+L G+V
Sbjct: 471 AEDSSKVSGGTPIKIEDPNQFVPLNTNPNEVLEKRNKIREQNRYDLKTAGPQSQLLAGIV 530

Query: 529 MDR--SLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGS 586
           +D+  S +Q E         + ++ P        PNPF+ LT+ ELEEY+R +ERKQ+G 
Sbjct: 531 VDKPPSTMQFE---------DDDHGP-----PAPPNPFSHLTEGELEEYKRTIERKQQGL 576

Query: 587 EENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSP 646
           EEN     E   KS      +    P   +  ++D+       D  D    + +    S 
Sbjct: 577 EEN----HELFSKS-----FISMEVPVMVVNGKDDM------HDVEDELAKRVSRLSTST 621

Query: 647 DEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPG 706
              +  +     EK EE              SPE +P  +P                   
Sbjct: 622 TIENIEITIKSPEKIEEV------------LSPEGSPSKSP------------------- 650

Query: 707 SDGSPGKSPSKKKKKFRTPSFLKKSKKK 734
                    SKKKKKFRTPSFLKK+KKK
Sbjct: 651 ---------SKKKKKFRTPSFLKKNKKK 669


>gi|9257192 adducin 2 isoform a [Homo sapiens]
          Length = 726

 Score =  633 bits (1632), Expect = 0.0
 Identities = 348/733 (47%), Positives = 476/733 (64%), Gaps = 32/733 (4%)

Query: 12  SPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSMILQSPAFCEEL 71
           SPPP   P  + YFDR  E++PEY+R RN A DLRQDFN+MEQKKRV+MILQSP+F EEL
Sbjct: 11  SPPP---PQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQSPSFREEL 67

Query: 72  ESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMSLGMVTPVNDLR 131
           E +IQEQ KKG N + + AL+QIADFM +    V+P +        +M++ M+TP+NDL 
Sbjct: 68  EGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTS--------SMNVSMMTPINDLH 119

Query: 132 GSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHFLIVPFGLLYSE 191
            +DS+   KGE+L+RCK+++ YRL DL+GW+QL   ++T RV+ EQ+HFLI P G+  SE
Sbjct: 120 TADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSE 179

Query: 192 VTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHIHTPAGAAVSAM 251
           VTASSL+K+N+ G++V++GS+   V+  GF LHSAIYAARPDV+C++H+HTPA AAVSAM
Sbjct: 180 VTASSLIKVNILGEVVEKGSSCFPVDTTGFCLHSAIYAARPDVRCIIHLHTPATAAVSAM 239

Query: 252 KCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILRNHGLVSVGESV 311
           K GLLP+S  AL +G++AY+D++G +  E +++ +QK LGP  K+L+LRNHG+V++G++V
Sbjct: 240 KWGLLPVSHNALLVGDMAYYDFNGEMEQEADRINLQKCLGPTCKILVLRNHGVVALGDTV 299

Query: 312 EEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPVGEGTGSPPKWQ 371
           EEAFY I +L  ACEIQV  L+SAGG +NL+LL  EK++          G   G   K +
Sbjct: 300 EEAFYKIFHLQAACEIQVSALSSAGGVENLILLEQEKHRPHEVGSVQWAGSTFGPMQKSR 359

Query: 372 IGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYSFASDGDSGTCS 431
           +GE EFEALMRMLDNLGYRTGY YR+P ++EK+K  S+VE+PA+VT + F  DG      
Sbjct: 360 LGEHEFEALMRMLDNLGYRTGYTYRHPFVQEKTKHKSEVEIPATVTAFVFEEDG--APVP 417

Query: 432 PLRHSFQKQQREKTRWLNSG----RGDEASEEGQNGSSPKSKTKWTKEDGHRTSTSAV-- 485
            LR   QKQQ+EKTRWLN+     R + A E  ++  SP+ KT W K D    S+S +  
Sbjct: 418 ALRQHAQKQQKEKTRWLNTPNTYLRVNVADEVQRSMGSPRPKTTWMKADEVEKSSSGMPI 477

Query: 486 ----PNLFVPLNTNPKEVQEMRNKIREQNLQDIKTAGPQSQVLCGVVMDRSLVQGELVTA 541
               PN FVPL T+P+EV EMRNKIREQN QD+K+AGPQSQ+L  V+ ++S       T 
Sbjct: 478 RIENPNQFVPLYTDPQEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPS---TE 534

Query: 542 SKAIIEKEYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKSP 601
           S+ + + +         T PNPF+ LTD+ELEEY++EVERK+   +   + A E+     
Sbjct: 535 SQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPA 594

Query: 602 PDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKE 661
              PA P   P+   + +  LV    + ++    T         P E ++  G  +  +E
Sbjct: 595 KSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEP-ETTQPEGVVVNGRE 653

Query: 662 EEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKKKKK 721
           EE       ++  ++ +     D      + +    E   +     +GSP KSPSKKKKK
Sbjct: 654 EEQTAEEILSKGLSQMTTSADTD-----VDTSKDKTESVTSGPMSPEGSPSKSPSKKKKK 708

Query: 722 FRTPSFLKKSKKK 734
           FRTPSFLKKSKKK
Sbjct: 709 FRTPSFLKKSKKK 721


>gi|9257190 adducin 2 isoform e [Homo sapiens]
          Length = 643

 Score =  589 bits (1518), Expect = e-168
 Identities = 314/606 (51%), Positives = 423/606 (69%), Gaps = 32/606 (5%)

Query: 12  SPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSMILQSPAFCEEL 71
           SPPP   P  + YFDR  E++PEY+R RN A DLRQDFN+MEQKKRV+MILQSP+F EEL
Sbjct: 11  SPPP---PQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQSPSFREEL 67

Query: 72  ESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMSLGMVTPVNDLR 131
           E +IQEQ KKG N + + AL+QIADFM +    V+P +        +M++ M+TP+NDL 
Sbjct: 68  EGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTS--------SMNVSMMTPINDLH 119

Query: 132 GSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHFLIVPFGLLYSE 191
            +DS+   KGE+L+RCK+++ YRL DL+GW+QL   ++T RV+ EQ+HFLI P G+  SE
Sbjct: 120 TADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSE 179

Query: 192 VTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHIHTPAGAAVSAM 251
           VTASSL+K+N+ G++V++GS+   V+  GF LHSAIYAARPDV+C++H+HTPA AAVSAM
Sbjct: 180 VTASSLIKVNILGEVVEKGSSCFPVDTTGFCLHSAIYAARPDVRCIIHLHTPATAAVSAM 239

Query: 252 KCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILRNHGLVSVGESV 311
           K GLLP+S  AL +G++AY+D++G +  E +++ +QK LGP  K+L+LRNHG+V++G++V
Sbjct: 240 KWGLLPVSHNALLVGDMAYYDFNGEMEQEADRINLQKCLGPTCKILVLRNHGVVALGDTV 299

Query: 312 EEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPVGEGTGSPPKWQ 371
           EEAFY I +L  ACEIQV  L+SAGG +NL+LL  EK++          G   G   K +
Sbjct: 300 EEAFYKIFHLQAACEIQVSALSSAGGVENLILLEQEKHRPHEVGSVQWAGSTFGPMQKSR 359

Query: 372 IGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYSFASDGDSGTCS 431
           +GE EFEALMRMLDNLGYRTGY YR+P ++EK+K  S+VE+PA+VT + F  DG      
Sbjct: 360 LGEHEFEALMRMLDNLGYRTGYTYRHPFVQEKTKHKSEVEIPATVTAFVFEEDG--APVP 417

Query: 432 PLRHSFQKQQREKTRWLNSG----RGDEASEEGQNGSSPKSKTKWTKEDGHRTSTSAV-- 485
            LR   QKQQ+EKTRWLN+     R + A E  ++  SP+ KT W K D    S+S +  
Sbjct: 418 ALRQHAQKQQKEKTRWLNTPNTYLRVNVADEVQRSMGSPRPKTTWMKADEVEKSSSGMPI 477

Query: 486 ----PNLFVPLNTNPKEVQEMRNKIREQNLQDIKTAGPQSQVLCGVVMDRSLVQGELVTA 541
               PN FVPL T+P+EV EMRNKIREQN QD+K+AGPQSQ+L  V+ ++S       T 
Sbjct: 478 RIENPNQFVPLYTDPQEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPS---TE 534

Query: 542 SKAIIEKEYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKSP 601
           S+ + + +         T PNPF+ LTD+ELEEY++EVERK+      LDE  +++E  P
Sbjct: 535 SQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEYKKEVERKKL----ELDETGQERE--P 588

Query: 602 PDQPAV 607
              PAV
Sbjct: 589 GSGPAV 594


>gi|89276787 adducin 2 isoform b [Homo sapiens]
          Length = 559

 Score =  555 bits (1431), Expect = e-158
 Identities = 286/531 (53%), Positives = 383/531 (72%), Gaps = 23/531 (4%)

Query: 12  SPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSMILQSPAFCEEL 71
           SPPP   P  + YFDR  E++PEY+R RN A DLRQDFN+MEQKKRV+MILQSP+F EEL
Sbjct: 11  SPPP---PQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQSPSFREEL 67

Query: 72  ESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMSLGMVTPVNDLR 131
           E +IQEQ KKG N + + AL+QIADFM +    V+P +        +M++ M+TP+NDL 
Sbjct: 68  EGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTS--------SMNVSMMTPINDLH 119

Query: 132 GSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHFLIVPFGLLYSE 191
            +DS+   KGE+L+RCK+++ YRL DL+GW+QL   ++T RV+ EQ+HFLI P G+  SE
Sbjct: 120 TADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSE 179

Query: 192 VTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHIHTPAGAAVSAM 251
           VTASSL+K+N+ G++V++GS+   V+  GF LHSAIYAARPDV+C++H+HTPA AAVSAM
Sbjct: 180 VTASSLIKVNILGEVVEKGSSCFPVDTTGFCLHSAIYAARPDVRCIIHLHTPATAAVSAM 239

Query: 252 KCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILRNHGLVSVGESV 311
           K GLLP+S  AL +G++AY+D++G +  E +++ +QK LGP  K+L+LRNHG+V++G++V
Sbjct: 240 KWGLLPVSHNALLVGDMAYYDFNGEMEQEADRINLQKCLGPTCKILVLRNHGVVALGDTV 299

Query: 312 EEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPVGEGTGSPPKWQ 371
           EEAFY I +L  ACEIQV  L+SAGG +NL+LL  EK++          G   G   K +
Sbjct: 300 EEAFYKIFHLQAACEIQVSALSSAGGVENLILLEQEKHRPHEVGSVQWAGSTFGPMQKSR 359

Query: 372 IGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYSFASDGDSGTCS 431
           +GE EFEALMRMLDNLGYRTGY YR+P ++EK+K  S+VE+PA+VT + F  DG      
Sbjct: 360 LGEHEFEALMRMLDNLGYRTGYTYRHPFVQEKTKHKSEVEIPATVTAFVFEEDG--APVP 417

Query: 432 PLRHSFQKQQREKTRWLNSG----RGDEASEEGQNGSSPKSKTKWTKEDGHRTSTSAV-- 485
            LR   QKQQ+EKTRWLN+     R + A E  ++  SP+ KT W K D    S+S +  
Sbjct: 418 ALRQHAQKQQKEKTRWLNTPNTYLRVNVADEVQRSMGSPRPKTTWMKADEVEKSSSGMPI 477

Query: 486 ----PNLFVPLNTNPKEVQEMRNKIREQNLQDIKTAGPQSQVLCGVVMDRS 532
               PN FVPL T+P+EV EMRNKIREQN QD+K+AGPQSQ+L  V+ ++S
Sbjct: 478 RIENPNQFVPLYTDPQEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKS 528


>gi|89276790 adducin 2 isoform d [Homo sapiens]
          Length = 253

 Score =  208 bits (530), Expect = 1e-53
 Identities = 110/209 (52%), Positives = 145/209 (69%), Gaps = 11/209 (5%)

Query: 12  SPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSMILQSPAFCEEL 71
           SPPP   P  + YFDR  E++PEY+R RN A DLRQDFN+MEQKKRV+MILQSP+F EEL
Sbjct: 11  SPPP---PQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQSPSFREEL 67

Query: 72  ESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMSLGMVTPVNDLR 131
           E +IQEQ KKG N + + AL+QIADFM +    V+P +        +M++ M+TP+NDL 
Sbjct: 68  EGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTS--------SMNVSMMTPINDLH 119

Query: 132 GSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHFLIVPFGLLYSE 191
            +DS+   KGE+L+RCK+++ YRL DL+GW+QL   ++T RV+ EQ+HFLI P G+  SE
Sbjct: 120 TADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSE 179

Query: 192 VTASSLVKINLQGDIVDRGSTNLGVNQAG 220
           VTASSL+K  L+     R      V  AG
Sbjct: 180 VTASSLIKEVLEMRNKIREQNRQDVKSAG 208



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 25/36 (69%), Positives = 31/36 (86%)

Query: 497 KEVQEMRNKIREQNLQDIKTAGPQSQVLCGVVMDRS 532
           KEV EMRNKIREQN QD+K+AGPQSQ+L  V+ ++S
Sbjct: 187 KEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKS 222


>gi|9257180 adducin 2 isoform c [Homo sapiens]
          Length = 420

 Score =  208 bits (530), Expect = 1e-53
 Identities = 110/209 (52%), Positives = 145/209 (69%), Gaps = 11/209 (5%)

Query: 12  SPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSMILQSPAFCEEL 71
           SPPP   P  + YFDR  E++PEY+R RN A DLRQDFN+MEQKKRV+MILQSP+F EEL
Sbjct: 11  SPPP---PQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQSPSFREEL 67

Query: 72  ESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMSLGMVTPVNDLR 131
           E +IQEQ KKG N + + AL+QIADFM +    V+P +        +M++ M+TP+NDL 
Sbjct: 68  EGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTS--------SMNVSMMTPINDLH 119

Query: 132 GSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHFLIVPFGLLYSE 191
            +DS+   KGE+L+RCK+++ YRL DL+GW+QL   ++T RV+ EQ+HFLI P G+  SE
Sbjct: 120 TADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSE 179

Query: 192 VTASSLVKINLQGDIVDRGSTNLGVNQAG 220
           VTASSL+K  L+     R      V  AG
Sbjct: 180 VTASSLIKEVLEMRNKIREQNRQDVKSAG 208



 Score =  132 bits (332), Expect = 1e-30
 Identities = 87/238 (36%), Positives = 124/238 (52%), Gaps = 9/238 (3%)

Query: 497 KEVQEMRNKIREQNLQDIKTAGPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIV 556
           KEV EMRNKIREQN QD+K+AGPQSQ+L  V+ ++S       T S+ + + +       
Sbjct: 187 KEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPS---TESQLMSKGDEDTKDDS 243

Query: 557 STTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPI 616
             T PNPF+ LTD+ELEEY++EVERK+   +   + A E+        PA P   P+   
Sbjct: 244 EETVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEA 303

Query: 617 KLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTE 676
           + +  LV    + ++    T         P E ++  G  +  +EEE       ++  ++
Sbjct: 304 ETKSPLVSPSKSLEEGTKKTETSKAATTEP-ETTQPEGVVVNGREEEQTAEEILSKGLSQ 362

Query: 677 ASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKKKKKFRTPSFLKKSKKK 734
            +     D      + +    E   +     +GSP KSPSKKKKKFRTPSFLKKSKKK
Sbjct: 363 MTTSADTD-----VDTSKDKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKKSKKK 415


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 53/193 (27%), Positives = 86/193 (44%), Gaps = 17/193 (8%)

Query: 545 IIEKEYQPHVIVSTTGPNPFTT--LTDRELEEYRREVERKQKGSEENLDEAREQKEKSPP 602
           ++EK  +  VIV         T  +T+ E +E + E  ++++G EE   E  E++ KSPP
Sbjct: 446 VVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPP 505

Query: 603 -DQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKE 661
            ++ A P     +P+K E     E  + +  +A   K      SP++            +
Sbjct: 506 AEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEA---KSPAEVKSPEKAKS-------PAK 555

Query: 662 EEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKKKKK 721
           EEA  PP       E +  PA   +P  E+A   A EE  A  P    SP K+ S  K++
Sbjct: 556 EEAKSPPEAKSPEKEEAKSPAEVKSP--EKAKSPAKEE--AKSPAEAKSPEKAKSPVKEE 611

Query: 722 FRTPSFLKKSKKK 734
            ++P+  K   K+
Sbjct: 612 AKSPAEAKSPVKE 624



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 65/305 (21%), Positives = 115/305 (37%), Gaps = 24/305 (7%)

Query: 431  SPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGS-----SPKSKTKWTKEDGHRTSTSAV 485
            SP++   +  ++ K+      +  E ++  +        SP++KT   KE+    +    
Sbjct: 724  SPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTP-AKEEARSPADKFP 782

Query: 486  PNLFVPLNTNPKEVQEMRNKIREQNLQDIKTAGPQSQVLCGVVMDRSLVQGELVTASKAI 545
                 P+    K  ++ ++ ++E      K   P+ + +   V +    Q   V      
Sbjct: 783  EKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEI-PKKEEVKSPVKEEEKPQEVKVKEPPKK 841

Query: 546  IEKEYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAR-EQKEKSPPDQ 604
             E+E  P     T            + E  + +VE K++ + E   E++ E K++   D+
Sbjct: 842  AEEEKAP-ATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDK 900

Query: 605  PAVPHPPPSTPIKLE--EDLVPEPTT----GDDSDAATFKPTLPDLSPDEPSEALGFPML 658
              VP P    P K+E  ED  P+  T     +  DA   +P+     P E  EA      
Sbjct: 901  KKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPS----KPAEKKEAAPEKKD 956

Query: 659  EKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSA--VEEGAAADPGSDGSPGKSPS 716
             KEE+A +   P E P   +     D     E + P A   E+ ++ D      P K+  
Sbjct: 957  TKEEKAKK---PEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATE 1013

Query: 717  KKKKK 721
             K  K
Sbjct: 1014 DKAAK 1018



 Score = 34.3 bits (77), Expect = 0.43
 Identities = 32/143 (22%), Positives = 52/143 (36%), Gaps = 17/143 (11%)

Query: 578 EVERKQKGSEENLDEARE-QKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAAT 636
           EV+  +K      +EA+  +K KSP  + A       +P+K E     +  +   ++A  
Sbjct: 631 EVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAK- 689

Query: 637 FKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSA 696
                   SP++    +       +EEA  P        E +  P    +PV EEA    
Sbjct: 690 --------SPEKAKSPV-------KEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPE 734

Query: 697 VEEGAAADPGSDGSPGKSPSKKK 719
             +    +        KSP K K
Sbjct: 735 KAKSPVKEEAKSPEKAKSPEKAK 757



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 41/191 (21%), Positives = 71/191 (37%), Gaps = 29/191 (15%)

Query: 569 DRELEEYRREVERKQKGSEENLDEARE-------QKEKSPPDQPAVPHPPPSTPIKLEED 621
           ++E  +   EV+  +K      +EA+        +K KSP  + A       +P+K E  
Sbjct: 568 EKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAK 627

Query: 622 LVPEPTTGDDSDAATF-------KPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAP 674
              E  + + + + T        K   P+    +  E    P+  + +   +  SP +A 
Sbjct: 628 SPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAE 687

Query: 675 TEASPEPAPDP------------APVAEEAAPSAVEEGAAADPGSDGSPGKSPSKKKKKF 722
            + SPE A  P            +PV EEA      +    +        KSP K++ K 
Sbjct: 688 AK-SPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAK- 745

Query: 723 RTPSFLKKSKK 733
            +P   K  +K
Sbjct: 746 -SPEKAKSPEK 755


>gi|30795231 brain abundant, membrane attached signal protein 1
           [Homo sapiens]
          Length = 227

 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 48/183 (26%), Positives = 76/183 (41%), Gaps = 12/183 (6%)

Query: 541 ASKAIIEKEYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKS 600
           A  A  E+E  P          P      +E  +   E + ++K  E++   A+E+  K+
Sbjct: 26  AEGAATEEEGTPKESEPQAAAEPAEAKEGKEKPDQDAEGKAEEKEGEKDAAAAKEEAPKA 85

Query: 601 PPDQPAVPHPPPSTPIKL--EEDLVPEPTTGDDSDAATFKPTLPDLSP-----DEPSEAL 653
            P++        + P K   +E   P P  G ++  A      P  S      +EPS+  
Sbjct: 86  EPEKTEGAAEAKAEPPKAPEQEQAAPGPAAGGEAPKAAEAAAAPAESAAPAAGEEPSKEE 145

Query: 654 GFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGK 713
           G P   K+ EA  P +P    T++   PA D  P + EAAPS+ E  AA +  S     +
Sbjct: 146 GEP---KKTEA--PAAPAAQETKSDGAPASDSKPGSSEAAPSSKETPAATEAPSSTPKAQ 200

Query: 714 SPS 716
            P+
Sbjct: 201 GPA 203



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 48/176 (27%), Positives = 71/176 (40%), Gaps = 25/176 (14%)

Query: 573 EEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDS 632
           +E  +E ++K +G+    +   ++ E     +PA        P +  E    E     + 
Sbjct: 16  DEKAKEKDKKAEGAATEEEGTPKESEPQAAAEPAEAKEGKEKPDQDAEGKAEEKE--GEK 73

Query: 633 DAATFKPTLPDLSPDEP---SEALGFPML--EKEEEAHRPPSPTEAP--TEASPEPAPDP 685
           DAA  K   P   P++    +EA   P    E+E+ A  P +  EAP   EA+  PA   
Sbjct: 74  DAAAAKEEAPKAEPEKTEGAAEAKAEPPKAPEQEQAAPGPAAGGEAPKAAEAAAAPAESA 133

Query: 686 APVAEE---------------AAPSAVEEGAAADPGSDGSPGKSPSKKKKKFRTPS 726
           AP A E               AAP+A E  +   P SD  PG S +    K  TP+
Sbjct: 134 APAAGEEPSKEEGEPKKTEAPAAPAAQETKSDGAPASDSKPGSSEAAPSSK-ETPA 188



 Score = 33.1 bits (74), Expect = 0.95
 Identities = 33/156 (21%), Positives = 53/156 (33%), Gaps = 25/156 (16%)

Query: 569 DRELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPS--TPIKLEEDLVP-- 624
           +++    + E  + +    E   EA+ +  K+P  + A P P      P   E    P  
Sbjct: 72  EKDAAAAKEEAPKAEPEKTEGAAEAKAEPPKAPEQEQAAPGPAAGGEAPKAAEAAAAPAE 131

Query: 625 --------EPTTGDDSDAATFKPTLP----------DLSPDEPSEALGFPMLEKEEEAHR 666
                   EP+  +     T  P  P            S  +P  +   P  ++   A  
Sbjct: 132 SAAPAAGEEPSKEEGEPKKTEAPAAPAAQETKSDGAPASDSKPGSSEAAPSSKETPAATE 191

Query: 667 PPSPT---EAPTEASPEPAPDPAPVAEEAAPSAVEE 699
            PS T   + P  ++ EP P  AP A       V+E
Sbjct: 192 APSSTPKAQGPAASAEEPKPVEAPAANSDQTVTVKE 227


>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
          Length = 1970

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 37/140 (26%), Positives = 59/140 (42%), Gaps = 2/140 (1%)

Query: 600  SPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAA-TFKPTLPDLSPDEPSEALGFPML 658
            SP   P  P   P++P          PT+   S  + ++ PT P  SP  PS +   P  
Sbjct: 1689 SPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNY 1748

Query: 659  EKEEEAHRPPSPTEAPTEASPEP-APDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSK 717
                  + P SP+ +PT  S  P +P+  P +   +P++      +   S  SP  SPS 
Sbjct: 1749 SPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSS 1808

Query: 718  KKKKFRTPSFLKKSKKKSDS 737
             +   ++P++   S   S S
Sbjct: 1809 PRYTPQSPTYTPSSPSYSPS 1828



 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 37/138 (26%), Positives = 60/138 (43%), Gaps = 2/138 (1%)

Query: 600  SPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAA-TFKPTLPDLSPDEPSEALGFPML 658
            SP   P  P   P++P          PT+ + S  + ++ PT P  SP  PS +   P  
Sbjct: 1752 SPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRY 1811

Query: 659  EKEEEAHRPPSPTEAPTEASPEP-APDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSK 717
              +   + P SP+ +P+  S  P +P   P +   +PS+ E    +   S  SP  SP+ 
Sbjct: 1812 TPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTS 1871

Query: 718  KKKKFRTPSFLKKSKKKS 735
             K    +P++   + K S
Sbjct: 1872 PKYSPTSPTYSPTTPKYS 1889



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 36/138 (26%), Positives = 57/138 (41%), Gaps = 2/138 (1%)

Query: 600  SPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAA-TFKPTLPDLSPDEPSEALGFPML 658
            SP   P  P   P++P          PT+   S  + ++ PT P  SP  PS +   P  
Sbjct: 1633 SPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSY 1692

Query: 659  EKEEEAHRPPSPTEAPTEASPEP-APDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSK 717
                 ++ P SP+ +PT  S  P +P  +P +   +P++      +   S  SP  SP+ 
Sbjct: 1693 SPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTS 1752

Query: 718  KKKKFRTPSFLKKSKKKS 735
                  +PS+   S   S
Sbjct: 1753 PNYTPTSPSYSPTSPSYS 1770



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 35/140 (25%), Positives = 56/140 (40%), Gaps = 8/140 (5%)

Query: 602  PDQPAVPHP-----PPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFP 656
            P  P +P P     P  +P     +  P    G    + ++ PT P  SP  PS +   P
Sbjct: 1577 PSSPYIPSPGGAMSPSYSPTSPAYE--PRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSP 1634

Query: 657  MLEKEEEAHRPPSPTEAPTEASPEP-APDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSP 715
                   ++ P SP+ +PT  S  P +P  +P +   +P++      +   S  SP  SP
Sbjct: 1635 NYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP 1694

Query: 716  SKKKKKFRTPSFLKKSKKKS 735
            +       +PS+   S   S
Sbjct: 1695 TSPSYSPTSPSYSPTSPSYS 1714



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 36/140 (25%), Positives = 55/140 (39%), Gaps = 2/140 (1%)

Query: 600  SPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAA-TFKPTLPDLSPDEPSEALGFPML 658
            SP   P  P   P++P          PT+   S  +  + PT P+ +P  PS +   P  
Sbjct: 1710 SPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSY 1769

Query: 659  EKEEEAHRPPSPTEAPTEASPEP-APDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSK 717
                  + P SP  +PT  S  P +P  +P +   +PS+      +   +  SP  SPS 
Sbjct: 1770 SPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSS 1829

Query: 718  KKKKFRTPSFLKKSKKKSDS 737
                  +P +   S   S S
Sbjct: 1830 PSYSPTSPKYTPTSPSYSPS 1849



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 31/130 (23%), Positives = 56/130 (43%), Gaps = 2/130 (1%)

Query: 600  SPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAA-TFKPTLPDLSPDEPSEALGFPML 658
            SP   P  P+  P++P          PT+   S  + ++ P+ P  +P  P+     P  
Sbjct: 1766 SPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSY 1825

Query: 659  EKEEEAHRPPSPTEAPTEASPEPA-PDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSK 717
                 ++ P SP   PT  S  P+ P+  P + + +P++ +    +   S  SP  SP+ 
Sbjct: 1826 SPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTT 1885

Query: 718  KKKKFRTPSF 727
             K    +P++
Sbjct: 1886 PKYSPTSPTY 1895



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 34/128 (26%), Positives = 56/128 (43%), Gaps = 11/128 (8%)

Query: 600  SPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAA-TFKPTLPDLSPDEPSEALGFPML 658
            SP   P+ P   P++P          PT+   S  + T+ PT P  SP  P+ +   P+ 
Sbjct: 1843 SPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVY 1902

Query: 659  EKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKK 718
                  + P SPT +PT      +P  +P +   +P++  +G+   P    SPG SP+  
Sbjct: 1903 TPTSPKYSPTSPTYSPT------SPKYSPTSPTYSPTS-PKGSTYSP---TSPGYSPTSP 1952

Query: 719  KKKFRTPS 726
                 +P+
Sbjct: 1953 TYSLTSPA 1960



 Score = 37.0 bits (84), Expect = 0.066
 Identities = 28/112 (25%), Positives = 39/112 (34%), Gaps = 1/112 (0%)

Query: 595  EQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAA-TFKPTLPDLSPDEPSEAL 653
            E    SP   P  P   P++P          PTT   S  + T+ PT P  +P  P  + 
Sbjct: 1852 EYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSP 1911

Query: 654  GFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADP 705
              P        + P SPT +PT          +P     +P+      A  P
Sbjct: 1912 TSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSPTSPTYSLTSPAISP 1963


>gi|110349717 titin isoform novex-2 [Homo sapiens]
          Length = 27118

 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 51/166 (30%), Positives = 70/166 (42%), Gaps = 33/166 (19%)

Query: 577  REVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIK--------LEEDLVPEPTT 628
            + V RK+   EE      E K+     +PAVP PPP  P++          E  +PEPT 
Sbjct: 4645 KSVLRKRPEEEE---PKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPT- 4700

Query: 629  GDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPV 688
                     KP +P L   EP      P  E E +  +PP P E      PEP P  APV
Sbjct: 4701 ----KVPEIKPAIP-LPAPEPK-----PKPEAEVKTIKPP-PVE------PEPTPIAAPV 4743

Query: 689  AEEAAPSAVEEGAAADPGSDGSPGKSPSKKKKKFRTPSFLKKSKKK 734
                 P   ++  A  P  + +  K P K   K +TPS ++  ++K
Sbjct: 4744 ---TVPVVGKKAEAKAPKEEAAKPKGPIKGVPK-KTPSPIEAERRK 4785


>gi|110349713 titin isoform novex-1 [Homo sapiens]
          Length = 27051

 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 51/166 (30%), Positives = 70/166 (42%), Gaps = 33/166 (19%)

Query: 577  REVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIK--------LEEDLVPEPTT 628
            + V RK+   EE      E K+     +PAVP PPP  P++          E  +PEPT 
Sbjct: 4578 KSVLRKRPEEEE---PKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPT- 4633

Query: 629  GDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPV 688
                     KP +P L   EP      P  E E +  +PP P E      PEP P  APV
Sbjct: 4634 ----KVPEIKPAIP-LPAPEPK-----PKPEAEVKTIKPP-PVE------PEPTPIAAPV 4676

Query: 689  AEEAAPSAVEEGAAADPGSDGSPGKSPSKKKKKFRTPSFLKKSKKK 734
                 P   ++  A  P  + +  K P K   K +TPS ++  ++K
Sbjct: 4677 ---TVPVVGKKAEAKAPKEEAAKPKGPIKGVPK-KTPSPIEAERRK 4718


>gi|110349715 titin isoform N2-B [Homo sapiens]
          Length = 26926

 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 51/166 (30%), Positives = 70/166 (42%), Gaps = 33/166 (19%)

Query: 577  REVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIK--------LEEDLVPEPTT 628
            + V RK+   EE      E K+     +PAVP PPP  P++          E  +PEPT 
Sbjct: 4453 KSVLRKRPEEEE---PKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPT- 4508

Query: 629  GDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPV 688
                     KP +P L   EP      P  E E +  +PP P E      PEP P  APV
Sbjct: 4509 ----KVPEIKPAIP-LPAPEPK-----PKPEAEVKTIKPP-PVE------PEPTPIAAPV 4551

Query: 689  AEEAAPSAVEEGAAADPGSDGSPGKSPSKKKKKFRTPSFLKKSKKK 734
                 P   ++  A  P  + +  K P K   K +TPS ++  ++K
Sbjct: 4552 ---TVPVVGKKAEAKAPKEEAAKPKGPIKGVPK-KTPSPIEAERRK 4593


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 71/328 (21%), Positives = 128/328 (39%), Gaps = 48/328 (14%)

Query: 440 QQREKTRWLNSGRGDEASEEGQNGSSPKSKTKWTKEDGHRTSTSAVPNLFVPLNTNPKEV 499
           +Q++K +  + GR  E+S      S  + + K +K+  HR+ + +        +  PK  
Sbjct: 186 KQKKKKKKKDRGRRSESS------SPRRERKKSSKKKKHRSESESKKRKH--RSPTPKSK 237

Query: 500 QEMRNKIREQNLQDIKTAGPQSQ-VLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIVST 558
           ++ ++K R+++     T  P+S+        D +       + S++   K +   +   +
Sbjct: 238 RKSKDKKRKRSRST--TPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRS 295

Query: 559 TGP-------------NPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKS----- 600
             P              P TT T R       E   KQ  S    D+ +++KEKS     
Sbjct: 296 PSPASGRRGEGDAPFSEPGTTSTQRPSSP---ETATKQPSSPYE-DKDKDKKEKSATRPS 351

Query: 601 --PPDQPAVPHPPPSTPIKLE------EDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEA 652
             P      P PP  TP+  E      + L   P + +  +  +      D SP +  E 
Sbjct: 352 PSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEK 411

Query: 653 LGFPMLEKEEEAHRPPSPTEAPTEAS-----PEPAPDPAPVAEEAAPSAVEEGAAADPGS 707
           L  P     E +   P PT+    AS     P+PAP P    E ++    +  +      
Sbjct: 412 L--PQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKR 469

Query: 708 DGSPGKSPSKKKKKFRTPSFLKKSKKKS 735
           D S   +PS++  + R+P+  K+ + +S
Sbjct: 470 DKSHSHTPSRRMGRSRSPATAKRGRSRS 497



 Score = 39.3 bits (90), Expect = 0.013
 Identities = 37/152 (24%), Positives = 55/152 (36%), Gaps = 19/152 (12%)

Query: 605  PAVPH-----PPPST------------PIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPD 647
            P VPH     PP ST            P K         ++   S +++   +    S  
Sbjct: 2499 PGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGS 2558

Query: 648  EPSEALGFPM-LEKEEEAHRPPSPTEAPTEASPE-PAPDPAPVAEEAAPSAVEEGAAADP 705
              S++ G  + ++ E    R PSPT AP EA  E   P+P P   +   S+    +++  
Sbjct: 2559 SSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSS 2618

Query: 706  GSDGSPGKSPSKKKKKFRTPSFLKKSKKKSDS 737
             S  S   S S       + S    S   S S
Sbjct: 2619 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPS 2650



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 21/77 (27%), Positives = 33/77 (42%), Gaps = 4/77 (5%)

Query: 659 EKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKK 718
           E ++ A  PP P     E+S   +P P    ++          ++ P  +    +  S K
Sbjct: 159 EAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRE----RKKSSK 214

Query: 719 KKKFRTPSFLKKSKKKS 735
           KKK R+ S  KK K +S
Sbjct: 215 KKKHRSESESKKRKHRS 231



 Score = 30.8 bits (68), Expect = 4.7
 Identities = 42/193 (21%), Positives = 72/193 (37%), Gaps = 46/193 (23%)

Query: 571  ELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAV-----------PHPPPSTPIKLE 619
            E+++  R   R Q GS    D + E K  +P   P             P P  S+  +  
Sbjct: 1603 EVKDKPRAAPRAQSGS----DSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESS 1658

Query: 620  EDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEK---------------EEEA 664
             +  P+  T      ++ +P     +P     +   P L +               E  +
Sbjct: 1659 PEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRS 1718

Query: 665  HRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSP--GKSPSKKKKKF 722
              PP    +P+ +SPEPA        E + S+    +A+ P +  +   G+SPS K    
Sbjct: 1719 RTPPRHRRSPSVSSPEPA--------EKSRSSRRRRSASSPRTKTTSRRGRSPSPK---- 1766

Query: 723  RTPSFLKKSKKKS 735
              P  L++S+ +S
Sbjct: 1767 --PRGLQRSRSRS 1777


>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo
           sapiens]
          Length = 2462

 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 45/149 (30%), Positives = 55/149 (36%), Gaps = 19/149 (12%)

Query: 596 QKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGF 655
           Q    PP       PPP  P    ED +P PT    +  AT  PT P   P   +     
Sbjct: 747 QNGPKPPATLGADGPPPGPPTPPPED-IPAPTEPTPASEATGAPTPPPAPPSPSAPPPVV 805

Query: 656 PMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADP-------GSD 708
           P  EKEEE    P     P E   E  P   P AEE    AV+ G A +P        ++
Sbjct: 806 PKEEKEEETAAAP-----PVEEGEEQKP---PAAEEL---AVDTGKAEEPVKSECTEEAE 854

Query: 709 GSPGKSPSKKKKKFRTPSFLKKSKKKSDS 737
             P K    +  +      LK  KK+  S
Sbjct: 855 EGPAKGKDAEAAEATAEGALKAEKKEGGS 883



 Score = 35.4 bits (80), Expect = 0.19
 Identities = 31/112 (27%), Positives = 46/112 (41%), Gaps = 10/112 (8%)

Query: 597  KEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFP 656
            +E + P +PA P PPP   ++ E D   +P  G      +  P  P  +  E  + + FP
Sbjct: 969  REDAAPTKPAPPAPPPPQNLQPESDAPQQP--GSSPRGKSRSPAPP--ADKEAEKPVFFP 1024

Query: 657  MLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGA--AADPG 706
                E +      P + P   S  P P P     +A+P A +  A   A PG
Sbjct: 1025 AFAAEAQ----KLPGDPPCWTSGLPFPVPPREVIKASPHAPDPSAFSYAPPG 1072



 Score = 33.1 bits (74), Expect = 0.95
 Identities = 33/128 (25%), Positives = 54/128 (42%), Gaps = 17/128 (13%)

Query: 621  DLVPEPTTGDDSDAATFKPTLPDLSPD-----EPSEALGFPMLEKEEEA---------HR 666
            D V E   GD +   + +P+L   + D      P + L    L++   A         H 
Sbjct: 907  DEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPIQVTKVHE 966

Query: 667  PPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKK-KKKFRTP 725
            PP    APT+ +P PAP P P   +    A ++  ++  G   SP     K+ +K    P
Sbjct: 967  PPREDAAPTKPAP-PAP-PPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFP 1024

Query: 726  SFLKKSKK 733
            +F  +++K
Sbjct: 1025 AFAAEAQK 1032


>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo
           sapiens]
          Length = 2524

 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 45/149 (30%), Positives = 55/149 (36%), Gaps = 19/149 (12%)

Query: 596 QKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGF 655
           Q    PP       PPP  P    ED +P PT    +  AT  PT P   P   +     
Sbjct: 764 QNGPKPPATLGADGPPPGPPTPPPED-IPAPTEPTPASEATGAPTPPPAPPSPSAPPPVV 822

Query: 656 PMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADP-------GSD 708
           P  EKEEE    P     P E   E  P   P AEE    AV+ G A +P        ++
Sbjct: 823 PKEEKEEETAAAP-----PVEEGEEQKP---PAAEEL---AVDTGKAEEPVKSECTEEAE 871

Query: 709 GSPGKSPSKKKKKFRTPSFLKKSKKKSDS 737
             P K    +  +      LK  KK+  S
Sbjct: 872 EGPAKGKDAEAAEATAEGALKAEKKEGGS 900



 Score = 35.4 bits (80), Expect = 0.19
 Identities = 31/112 (27%), Positives = 46/112 (41%), Gaps = 10/112 (8%)

Query: 597  KEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFP 656
            +E + P +PA P PPP   ++ E D   +P  G      +  P  P  +  E  + + FP
Sbjct: 985  REDAAPTKPAPPAPPPPQNLQPESDAPQQP--GSSPRGKSRSPAPP--ADKEAEKPVFFP 1040

Query: 657  MLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGA--AADPG 706
                E +      P + P   S  P P P     +A+P A +  A   A PG
Sbjct: 1041 AFAAEAQ----KLPGDPPCWTSGLPFPVPPREVIKASPHAPDPSAFSYAPPG 1088



 Score = 33.5 bits (75), Expect = 0.73
 Identities = 33/127 (25%), Positives = 54/127 (42%), Gaps = 16/127 (12%)

Query: 621  DLVPEPTTGDDSDAATFKPTLPDLSPD-----EPSEALGFPMLEKEEEA--------HRP 667
            D V E   GD +   + +P+L   + D      P + L    L++   A        H P
Sbjct: 924  DEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPIVTKVHEP 983

Query: 668  PSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKK-KKKFRTPS 726
            P    APT+ +P PAP P P   +    A ++  ++  G   SP     K+ +K    P+
Sbjct: 984  PREDAAPTKPAP-PAP-PPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPA 1041

Query: 727  FLKKSKK 733
            F  +++K
Sbjct: 1042 FAAEAQK 1048


>gi|62000702 diacylglycerol kinase kappa [Homo sapiens]
          Length = 1271

 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 41/137 (29%), Positives = 58/137 (42%), Gaps = 21/137 (15%)

Query: 595 EQKEKSP-PDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEAL 653
           EQ  +SP P  P  P PPP  P        P P    ++         P+L+P    EA 
Sbjct: 18  EQPAESPEPPPPWPPPPPPPAP-------PPAPPLLSEASPEPIPEPCPELAPGPCPEAT 70

Query: 654 GFPMLEKEEEAHRPPSP---TEAPTEASPEPAPDPAP-VAEEAAPSAVEEGAAADPGSDG 709
                E   E +  P+P   TE  +E +PEPA +PAP  A E AP       A +P ++ 
Sbjct: 71  S----ESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPE-----PAPEPATES 121

Query: 710 SPGKSPSKKKKKFRTPS 726
           +P  +P    +    P+
Sbjct: 122 APEPTPEPALESVPEPA 138



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 47/157 (29%), Positives = 59/157 (37%), Gaps = 28/157 (17%)

Query: 586 SEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLS 645
           +E   + A E   +  P+    P P P+T    E    PEP T + +   T +P L   S
Sbjct: 79  TEPTPEPATEPASEPAPEPATEPAPEPATEPAPEP--APEPAT-ESAPEPTPEPALE--S 133

Query: 646 PDEPSEALGFPMLEKEEEAHRPPSPTEAPT---------EASPEPAPDPAPVAEEAAPSA 696
             EP+     P L  E      P PT  P          EA+PE  P PAP   +     
Sbjct: 134 VPEPA-----PELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCPVDT 188

Query: 697 VEEGAAADPGSDGSPGKSPSKKKKKFRTPSFLKKSKK 733
            E G    P    SP  SPS      RTP    + KK
Sbjct: 189 RERGLKTSP----SPSPSPSP-----RTPMSWSRIKK 216



 Score = 39.3 bits (90), Expect = 0.013
 Identities = 31/96 (32%), Positives = 43/96 (44%), Gaps = 17/96 (17%)

Query: 631 DSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAP---TEASPEPAPDPAP 687
           D  AA  + T P    ++P+E+   P          PP+P  AP   +EASPEP P+P P
Sbjct: 2   DRGAAAAQGTAPPQDGEQPAESPEPP--PPWPPPPPPPAPPPAPPLLSEASPEPIPEPCP 59

Query: 688 -VAEEAAPSAVEEGA-----------AADPGSDGSP 711
            +A    P A  E A           A +P S+ +P
Sbjct: 60  ELAPGPCPEATSESATELYTEPTPEPATEPASEPAP 95


>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
            sapiens]
          Length = 1130

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 47/168 (27%), Positives = 67/168 (39%), Gaps = 28/168 (16%)

Query: 569  DRELEEYRREVERKQKGSEENLDEARE--------QKEKSPPDQPAVPH--PPPSTPIKL 618
            + E  E   E E + +  EE L+E  +        + E+  P  P +P   PPP +P K+
Sbjct: 936  EEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKV 995

Query: 619  EEDLVPEPT---------TGDDSDAATFKPTLPDLSPDE-------PSEALGFPMLEK-E 661
            + +  PEP          T ++  A T     P+  P +        S A G P  E  E
Sbjct: 996  QPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVE 1055

Query: 662  EEAHRPPSPTEAPTE-ASPEPAPDPAPVAEEAAPSAVEEGAAADPGSD 708
            EE   PP+  E  TE  S +  P P   AEE   +  E  A  +   D
Sbjct: 1056 EEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEALQEKEQD 1103



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 39/153 (25%), Positives = 64/153 (41%), Gaps = 19/153 (12%)

Query: 569  DRELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTT 628
            + E EE   E E +++  EE+ +E  E +E+   ++            + EE+   E   
Sbjct: 889  EEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEE-------EFEEEFEEEEGE 941

Query: 629  GDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPS------PTEAPTEASPEPA 682
             ++ +    +    +L   E  E  G    E EE A  PP+      P E+P +  PEP 
Sbjct: 942  LEEEEEEEDEEEEEELEEVEDLE-FGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPE 1000

Query: 683  PDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSP 715
            P+P  + E   P   EE      G+D +P  +P
Sbjct: 1001 PEPGLLLEVEEPGTEEE-----RGADTAPTLAP 1028



 Score = 37.4 bits (85), Expect = 0.050
 Identities = 40/125 (32%), Positives = 43/125 (34%), Gaps = 17/125 (13%)

Query: 601 PPDQP---AVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPT-LPDLSPDEPSEALGFP 656
           PPD+     VP P      K E   V      D  D+    P  LP L P  PS A   P
Sbjct: 751 PPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSGATPPP 810

Query: 657 MLEKEEEAHRPPSPT-EAPTEAS------PEPAPDPAPVAEEAA---PSAVEEGAAADPG 706
           +         PP P  E P E        P P P P PV        P  V EG    PG
Sbjct: 811 IAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEGT---PG 867

Query: 707 SDGSP 711
             G P
Sbjct: 868 GGGPP 872



 Score = 31.2 bits (69), Expect = 3.6
 Identities = 22/96 (22%), Positives = 37/96 (38%), Gaps = 10/96 (10%)

Query: 586  SEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDL---------VPEPTTGDDSDAAT 636
            S+  ++   E     PP Q  V   P + P  LEE+           PE    ++ +  T
Sbjct: 1033 SQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETET 1092

Query: 637  FKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTE 672
                L +   D+ +  L    ++   +  +PP PTE
Sbjct: 1093 EAEALQEKEQDDTAAMLA-DFIDCPPDDEKPPPPTE 1127


>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
          Length = 1094

 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 38/141 (26%), Positives = 54/141 (38%), Gaps = 10/141 (7%)

Query: 597 KEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFP 656
           K++SPP  P   + PP  P K  E +V  P+  + ++     P  P   P  P E     
Sbjct: 725 KDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEE----- 779

Query: 657 MLEKEEEAHRPPSPTEAPTEASPEPA-PDPAP--VAEEAAPSAVEEGAAADPGSDGSPGK 713
             +    A  PP      + ASPEPA P  +P  V+  AA S+        P     P  
Sbjct: 780 --QDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPP 837

Query: 714 SPSKKKKKFRTPSFLKKSKKK 734
           +P         P  + K  +K
Sbjct: 838 APPAPAPASSAPGHVAKLPQK 858



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 35/120 (29%), Positives = 51/120 (42%), Gaps = 14/120 (11%)

Query: 601 PPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEK 660
           PP +P  P+P  + P      +VP P +   +DA+   P  P  +     E+   P++ K
Sbjct: 673 PPSKPRSPNP--AAPALAAPAVVPGPVS--TTDASPQSPPTPQTTLTPLQES---PVISK 725

Query: 661 EEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVE--EGAAADPGSDGSPGKSPSKK 718
           ++    PPSP   P    P P P   P     APSA E  E    DP     P  +P ++
Sbjct: 726 DQSP--PPSP---PPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQ 780


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 47/163 (28%), Positives = 69/163 (42%), Gaps = 27/163 (16%)

Query: 577   REVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKL-----EEDLVPEPTTGDD 631
             + V RK+   EE   E ++ ++   P  P  P P P   +++      E  +PEPT    
Sbjct: 10950 KSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPT---- 11005

Query: 632   SDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEE 691
                   KP +P L   EP      P  E E +  +PP P E      PEP P  APV   
Sbjct: 11006 -KVPEIKPAIP-LPAPEPK-----PKPEAEVKTIKPP-PVE------PEPTPIAAPV--- 11048

Query: 692   AAPSAVEEGAAADPGSDGSPGKSPSKKKKKFRTPSFLKKSKKK 734
               P   ++  A  P  + +  K P K   K +TPS ++  ++K
Sbjct: 11049 TVPVVGKKAEAKAPKEEAAKPKGPIKGVPK-KTPSPIEAERRK 11090



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 69/316 (21%), Positives = 116/316 (36%), Gaps = 39/316 (12%)

Query: 394  PYRYPALREKSKKYSDVEVPASVTGYSFASDGDSGTCSPLRHSFQKQQREKTRWLNSGRG 453
            P+  P   E  + Y +++V A    +                 F++ Q    R      G
Sbjct: 9088 PFEQPYYEEPDEDYEEIKVEAKKEVHE-----------EWEEDFEEGQEYYEREEGYDEG 9136

Query: 454  DEASEEGQNGSSPKSKTKWTKEDGHRTSTSA-VPNLFVPLNTNPK--------EVQEMRN 504
            +E  EE           K   E+ H     A VP    P    PK        ++++   
Sbjct: 9137 EEEWEEAYQEREVIQVQKEVYEESHERKVPAKVPEKKAP--PPPKVIKKPVIEKIEKTSR 9194

Query: 505  KIREQNLQDIKTAGPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIVSTTGPNPF 564
            ++ E+ +Q  K      +++      R+ VQ E++      +  +     +V +     F
Sbjct: 9195 RMEEEKVQVTKVPEVSKKIV-PQKPSRTPVQEEVIEVKVPAVHTKK----MVISEEKMFF 9249

Query: 565  TTLTDRELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDLVP 624
             + T+ E+     EV+ K+  +EE +  A  ++ + PP  P +P  P        E++ P
Sbjct: 9250 ASHTEEEVSVTVPEVQ-KEIVTEEKIHVAISKRVEPPPKVPELPEKPAP------EEVAP 9302

Query: 625  EPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPA-P 683
             P        A   P +P      P E    P+ +KE  A  PP   E P +  PE   P
Sbjct: 9303 VPIPKKVEPPAPKVPEVP--KKPVPEEKKPVPVPKKEPAA--PPKVPEVPKKPVPEEKIP 9358

Query: 684  DPAPVAEEAAPSAVEE 699
             P    +EA P+ V E
Sbjct: 9359 VPVAKKKEAPPAKVPE 9374



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 50/190 (26%), Positives = 76/190 (40%), Gaps = 21/190 (11%)

Query: 537   ELVTASKAIIEKEYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQ 596
             E+V   K  +    +P V  +     P   + ++++ E    +  K +     + EA ++
Sbjct: 10531 EVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPE---AIPPKPESPPPEVPEAPKE 10587

Query: 597   --KEKSPPDQPAVPHPPPSTPIKLEE---DLVPEPTTGDDSDAATFKPTLPDLSPDEPSE 651
                EK  P  P  P  P  TP+K+ E   ++VPE             P  P++ P +  E
Sbjct: 10588 VVPEKKVPAAP--PKKPEVTPVKVPEAPKEVVPE------KKVPVPPPKKPEVPPTKVPE 10639

Query: 652   ALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPS-AVEEGAAADPGSDGS 710
                  + EK+     PP P   P    PE   +P  VA E  P+  VEE   A P     
Sbjct: 10640 VPKVAVPEKKVPEAIPPKPESPP----PEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTV 10695

Query: 711   PGKSPSKKKK 720
             P K P  +KK
Sbjct: 10696 PPKKPVPEKK 10705



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 40/154 (25%), Positives = 61/154 (39%), Gaps = 11/154 (7%)

Query: 587   EENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSP 646
             +E + E +    K P   PA     P  P+  E+  VP P   +      ++    +++P
Sbjct: 10754 KEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEP-EEIAP 10812

Query: 647   DE---PSEALGFPMLEKEEEAHRPPSPTEAPTEASPEP-----APDPAPVAEEAAPSAVE 698
             +E   P E    P+ E+EE    PP+  E P +  PE          AP  +E  P  V 
Sbjct: 10813 EEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVI 10872

Query: 699   EGAAADPGSDGSPGKSPSK--KKKKFRTPSFLKK 730
             E     P     P   P +  K+K F+  +  KK
Sbjct: 10873 EKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKK 10906



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 40/141 (28%), Positives = 58/141 (41%), Gaps = 20/141 (14%)

Query: 597   KEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFP 656
             ++K P   P  P  PP+   ++ +++VPE             P  P++ P +  E    P
Sbjct: 10731 EKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVA--------VPKKPEVPPAKVPEVPKKP 10782

Query: 657   MLEKE------EEAHRPPSPT-EAPTEASPEP--APD---PAPVAEEAAPSAVEEGAAAD 704
             +LE++      E A  PP    E P E +PE   AP+   P PVAEE  P         +
Sbjct: 10783 VLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEE 10842

Query: 705   PGSDGSPGKSPSKKKKKFRTP 725
             P       K P  KK +   P
Sbjct: 10843 PKKIIPEKKVPVIKKPEAPPP 10863



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 57/219 (26%), Positives = 88/219 (40%), Gaps = 33/219 (15%)

Query: 528   VMDRSLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTTLTDR-ELEEYRREVERKQKGS 586
             V+ +  ++ E+V A    I +E + H +        F  + +  +LE++R E E + +  
Sbjct: 10359 VVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGEFHEVEEFIKLEQHRVEEEHRVEKV 10418

Query: 587   EENLD--EARE----QKEKSPPDQPAV------PHPPPST-------PIKLEEDLVPEPT 627
                ++  EA E    +K K+PP  P +      P  PP+        P K+ E  VP+  
Sbjct: 10419 HRVIEVFEAEEVEVFEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPE--VPKKI 10476

Query: 628   TGDDSDAATFKPTLPD------LSPDE--PSEALGFPMLEKEEEAHRPPSPTEAPTEASP 679
               ++      +P +P       L P E  P + +  P  +K E    PP   EAP E  P
Sbjct: 10477 VVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAP--PPKVPEAPKEVVP 10534

Query: 680   E-PAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSK 717
             E   P P P   E  P+ V E   A       P   P K
Sbjct: 10535 EKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPK 10573



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 41/162 (25%), Positives = 63/162 (38%), Gaps = 20/162 (12%)

Query: 571   ELEEYRREVERKQKGSEENLDEARE---QKEKSPPDQPAVPHPPPSTPIKLEEDLVPE-- 625
             E EE   E E      EE L E  E   ++E+ PP++  VP      P   EE+++PE  
Sbjct: 10122 EEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVP---EEEVLPEVK 10178

Query: 626   -------PTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEAS 678
                    P           K  +P      P++    P   +E+    P      P E +
Sbjct: 10179 PKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVT 10238

Query: 679   PEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKKKK 720
              E  P+  P++EE  P   EE  + +   + +P + P   KK
Sbjct: 10239 EE--PEEEPISEEEIP---EEPPSIEEVEEVAPPRVPEVIKK 10275



 Score = 36.6 bits (83), Expect = 0.086
 Identities = 43/155 (27%), Positives = 58/155 (37%), Gaps = 17/155 (10%)

Query: 578   EVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPS-TPIKLEEDLVPEPTTGDDSDAAT 636
             EV RK    E+      ++KE  P   P VP  P    P+ + +   P P          
Sbjct: 9952  EVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAK-------- 10003

Query: 637   FKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEP-APDPAPVAEEAAPS 695
               P +P      P E +  P+ +K E    P    E P +  PE   P PAP   EA P+
Sbjct: 10004 -VPEVP--KKPVPEEKVPVPVPKKVEAP--PAKVPEVPKKPVPEKKVPVPAPKKVEAPPA 10058

Query: 696   AVEEGAAADPGSDGSPGKSPSKKKKKFRTPSFLKK 730
              V E        +  P  +P  KK +   P   KK
Sbjct: 10059 KVPEVPKKLIPEEKKP--TPVPKKVEAPPPKVPKK 10091



 Score = 35.4 bits (80), Expect = 0.19
 Identities = 50/215 (23%), Positives = 87/215 (40%), Gaps = 16/215 (7%)

Query: 496  PKEVQEMRNKIREQNLQDIKTAGPQSQVLCGV-VMDRS----LVQGELVTASKAIIEKEY 550
            P +V E R ++ ++    I+    + Q +  V +M+       ++ E V+  +    +EY
Sbjct: 9689 PAKVTEFRKRVVKEEKVSIEAPKREPQPIKEVTIMEEKERAYTLEEEAVSVQREEEYEEY 9748

Query: 551  QPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHP 610
            + +         P T   D+  E   RE ER ++  E   +  +    K  P++P VP  
Sbjct: 9749 EEYDYKEFEEYEP-TEEYDQYEEYEEREYERYEEHEEYITEPEKPIPVKPVPEEP-VPTK 9806

Query: 611  PPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEP----SEALGFPMLEKEEEAHR 666
            P + P K+ +  VPE             P  P   P+EP     E +   + ++E+E   
Sbjct: 9807 PKAPPAKVLKKAVPEEKVPVPIPKKLKPP--PPKVPEEPKKVFEEKIRISITKREKEQVT 9864

Query: 667  PPSPTEAPTEASPEPAPD--PAPVAEEAAPSAVEE 699
             P+  + P +     A +  P P  E A P  V E
Sbjct: 9865 EPA-AKVPMKPKRVVAEEKVPVPRKEVAPPVRVPE 9898



 Score = 35.0 bits (79), Expect = 0.25
 Identities = 40/149 (26%), Positives = 56/149 (37%), Gaps = 22/149 (14%)

Query: 572   LEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDD 631
             +EEY  E E +    EE      E     P   P VP  P    +  E+  VP P   + 
Sbjct: 9918  VEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKP----VPEEKKPVPVPKKKEA 9973

Query: 632   SDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEE 691
               A      +P++ P +P E +  P+L  ++E   P    E P +          PV EE
Sbjct: 9974  PPAK-----VPEV-PKKPEEKV--PVLIPKKEKPPPAKVPEVPKK----------PVPEE 10015

Query: 692   AAPSAVEEGAAADPGSDGSPGKSPSKKKK 720
               P  V +   A P       K P  +KK
Sbjct: 10016 KVPVPVPKKVEAPPAKVPEVPKKPVPEKK 10044



 Score = 34.7 bits (78), Expect = 0.33
 Identities = 38/143 (26%), Positives = 54/143 (37%), Gaps = 17/143 (11%)

Query: 595   EQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALG 654
             E+K   P  + A P   P  P K+EE  +  P   +          LP    +EP E   
Sbjct: 10196 EKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEE---------VLPVEVTEEPEEE-- 10244

Query: 655   FPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGS---P 711
                + +EE    PPS  E   E +P   P+    A   AP+ V +   A P         
Sbjct: 10245 --PISEEEIPEEPPSIEEVE-EVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPE 10301

Query: 712   GKSPSKKKKKFRTPSFLKKSKKK 734
              K P   +KK   P+ + +  KK
Sbjct: 10302 EKVPVPVQKKEAPPAKVPEVPKK 10324



 Score = 33.9 bits (76), Expect = 0.56
 Identities = 33/140 (23%), Positives = 52/140 (37%), Gaps = 20/140 (14%)

Query: 578  EVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPS-----TPIKLEEDLVPEPTTGDDS 632
            EV +K    E+      +++  +PP  P VP  P        P+  +++  P        
Sbjct: 9318 EVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQK 9377

Query: 633  DAATFK-------------PTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASP 679
               T +             P +P++   +  E    P+  KEEE   PP     P +  P
Sbjct: 9378 GVVTEEKITIVTQREESPPPAVPEIPKKKVPEERK-PVPRKEEEVPPPPKVPALPKKPVP 9436

Query: 680  EP-APDPAPVAEEAAPSAVE 698
            E     P PVA++A P   E
Sbjct: 9437 EEKVAVPVPVAKKAPPPRAE 9456



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 39/144 (27%), Positives = 52/144 (36%), Gaps = 19/144 (13%)

Query: 587   EENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSP 646
             E+ + EA   K +SPP  P V   P    + LEE   P     +   AA  + T+P   P
Sbjct: 10647 EKKVPEAIPPKPESPP--PEVFEEPEE--VALEEP--PAEVVEEPEPAAPPQVTVPPKKP 10700

Query: 647   DEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPE----------PAPDPAPVAEEAAPSA 696
                 +A   P +  ++    P    E P E  PE          P   PA V E      
Sbjct: 10701 VPEKKA---PAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVV 10757

Query: 697   VEEGAAADPGSDGSPGKSPSKKKK 720
              E+  A     +  P K P   KK
Sbjct: 10758 PEKKVAVPKKPEVPPAKVPEVPKK 10781



 Score = 30.0 bits (66), Expect = 8.0
 Identities = 48/212 (22%), Positives = 76/212 (35%), Gaps = 37/212 (17%)

Query: 537  ELVTASKAIIEKEYQ---PHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEA 593
            E++   K + E+ ++   P  +     P P   +        ++ V  K + +   ++E 
Sbjct: 9148 EVIQVQKEVYEESHERKVPAKVPEKKAPPPPKVI--------KKPVIEKIEKTSRRMEEE 9199

Query: 594  REQKEKSPP-DQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEA 652
            + Q  K P   +  VP  P  TP++ E   V  P         + +  +   S  E   +
Sbjct: 9200 KVQVTKVPEVSKKIVPQKPSRTPVQEEVIEVKVPAVHTKKMVIS-EEKMFFASHTEEEVS 9258

Query: 653  LGFPMLEKE----EEAH--------RPPSPTE-----APTEASPEPAPD----PAPVAEE 691
            +  P ++KE    E+ H         PP   E     AP E +P P P     PAP   E
Sbjct: 9259 VTVPEVQKEIVTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPE 9318

Query: 692  AAPSAVEEGAAADP---GSDGSPGKSPSKKKK 720
                 V E     P       +P K P   KK
Sbjct: 9319 VPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKK 9350


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 49/184 (26%), Positives = 73/184 (39%), Gaps = 17/184 (9%)

Query: 558 TTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKSPPDQ------PAVPHPP 611
           TT  N  T+   +E     +E +  +K S ++L    +   K  P        PA+  P 
Sbjct: 155 TTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPK 214

Query: 612 PSTPIKLEEDLVPEPTTGDDSDAATFK--PTLPDLSPDEPSEALGFPMLEKEEE--AHRP 667
             TP   +E   P  TT  +    T K  PT P      P+     P   KE      + 
Sbjct: 215 EPTPTTPKE---PASTTPKEPTPTTIKSAPTTP--KEPAPTTTKSAPTTPKEPAPTTTKE 269

Query: 668 PSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDG-SPGKSPSKKKKKFRTPS 726
           P+PT  P E +P    +PAP   ++AP+  +E A   P     +  K P+    K  TP+
Sbjct: 270 PAPT-TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPT 328

Query: 727 FLKK 730
             K+
Sbjct: 329 TPKE 332



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 43/148 (29%), Positives = 59/148 (39%), Gaps = 22/148 (14%)

Query: 599 KSPPDQPAVP------HPPPSTPIKLEEDLVPEPTTGDDSDAATFK---PTLPDLSPDEP 649
           KS P  P  P       P P+TP +      P PTT  +    T K   PT  + +P  P
Sbjct: 292 KSAPTTPKEPAPTTPKKPAPTTPKE------PAPTTPKEPTPTTPKEPAPTTKEPAPTTP 345

Query: 650 SEALGFPMLEKEEEAHRPPSPTE----APT---EASPEPAPDPAPVAEEAAPSAVEEGAA 702
            E       +      + P+PT     APT   E SP    +PAP   ++AP+  +E A 
Sbjct: 346 KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP 405

Query: 703 ADPGSDGSPGKSPSKKKKKFRTPSFLKK 730
               S  +  K PS    K   P+  K+
Sbjct: 406 TTTKSAPTTPKEPSPTTTKEPAPTTPKE 433



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 42/145 (28%), Positives = 56/145 (38%), Gaps = 16/145 (11%)

Query: 591 DEAREQKEKSP--PDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDE 648
           + A   KE +P  P +PA   P    P   +E   P PTT  +    T K   P  +P E
Sbjct: 332 EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE---PAPTTPKEPAPTTTKEPSPT-TPKE 387

Query: 649 PSEAL--GFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVA-EEAAPSAVEEGAAADP 705
           P+       P   KE       S    P E SP    +PAP   +E AP+  ++ A   P
Sbjct: 388 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP 447

Query: 706 GSDGSPGKSPSKKKKKFRTPSFLKK 730
                  K P+    K   P+  KK
Sbjct: 448 -------KEPAPTTPKEPAPTTTKK 465



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 36/131 (27%), Positives = 54/131 (41%), Gaps = 19/131 (14%)

Query: 597 KEKSP--PDQPA--VPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEA 652
           KE +P  P +PA     P P+TP +      P PT        T K   P  +P EP+  
Sbjct: 323 KEPTPTTPKEPAPTTKEPAPTTPKE------PAPTAPKKPAPTTPKEPAPT-TPKEPA-- 373

Query: 653 LGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGA---AADPGSDG 709
              P   KE     P  P    T+++P    +PAP   ++AP+  +E +     +P    
Sbjct: 374 ---PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT 430

Query: 710 SPGKSPSKKKK 720
               +P+  KK
Sbjct: 431 PKEPAPTTPKK 441



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 40/142 (28%), Positives = 58/142 (40%), Gaps = 22/142 (15%)

Query: 597 KEKSP--PDQPA---VPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKP--TLPDLSPDEP 649
           KE +P  P +PA      P P+TP +      P PTT   +   T +P  T    +P  P
Sbjct: 362 KEPAPTTPKEPAPTTTKEPSPTTPKE------PAPTTTKSAPTTTKEPAPTTTKSAPTTP 415

Query: 650 SEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVA-EEAAPSAVEEGAAADPGSD 708
            E       E      + P+PT  P + +P    +PAP   +E AP+  ++ A   P   
Sbjct: 416 KEPSPTTTKEPAPTTPKEPAPT-TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP--- 471

Query: 709 GSPGKSPSKKKKKFRTPSFLKK 730
               K P+    K   P+  KK
Sbjct: 472 ----KEPAPTTPKETAPTTPKK 489



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 37/131 (28%), Positives = 56/131 (42%), Gaps = 17/131 (12%)

Query: 595 EQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALG 654
           E+   + P++PA   P    P   EE   P PTT ++    T K   P+ +P EP+    
Sbjct: 496 EKLAPTTPEKPAPTTPEELAPTTPEE---PTPTTPEEPAPTTPKAAAPN-TPKEPA---- 547

Query: 655 FPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEA-APSAVEEGAAADPGSDGSPGK 713
            P   KE      P+PT  P E +P    + AP   +  AP+ ++E A   P        
Sbjct: 548 -PTTPKE------PAPT-TPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKEL 599

Query: 714 SPSKKKKKFRT 724
           +P+  K+   T
Sbjct: 600 APTTTKEPTST 610



 Score = 38.5 bits (88), Expect = 0.023
 Identities = 44/141 (31%), Positives = 62/141 (43%), Gaps = 26/141 (18%)

Query: 597 KEKSP--PDQPA---VPHPPPSTPIKLEEDLVPEPTTGDDSDAATFK---PTLPD-LSPD 647
           KE +P  P +PA      P P+TP +      P PTT  ++   T K   PT P+ L+P 
Sbjct: 448 KEPAPTTPKEPAPTTTKKPAPTTPKE------PAPTTPKETAPTTPKKLTPTTPEKLAPT 501

Query: 648 EPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVA-EEAAPSAVEEGAAADPG 706
            P +    P     EE    P+  E PT  +PE   +PAP   + AAP+  +E A   P 
Sbjct: 502 TPEK----PAPTTPEEL--APTTPEEPTPTTPE---EPAPTTPKAAAPNTPKEPAPTTPK 552

Query: 707 SDG-SPGKSPSKKKKKFRTPS 726
               +  K P+    K   P+
Sbjct: 553 EPAPTTPKEPAPTTPKETAPT 573



 Score = 36.6 bits (83), Expect = 0.086
 Identities = 36/131 (27%), Positives = 58/131 (44%), Gaps = 24/131 (18%)

Query: 603 DQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEE 662
           D+PA   P  + P   +E   P PTT          PT P+  P   SE +  P   KE 
Sbjct: 682 DKPAPTTPKETAPTTPKE---PAPTTPKKP-----APTTPETPPPTTSE-VSTPTTTKE- 731

Query: 663 EAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKKKKKF 722
               P +  ++P E++PE + +P P A E +P         +PG   +  K+P+  K + 
Sbjct: 732 ----PTTIHKSPDESTPELSAEPTPKALENSPK--------EPGVPTT--KTPAATKPEM 777

Query: 723 RTPSFLKKSKK 733
            T +  K +++
Sbjct: 778 TTTAKDKTTER 788



 Score = 35.0 bits (79), Expect = 0.25
 Identities = 37/179 (20%), Positives = 69/179 (38%), Gaps = 22/179 (12%)

Query: 557 STTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPI 616
           S T      T+      E +      ++ S +  ++    KE    ++ +     P++ +
Sbjct: 134 SDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKV 193

Query: 617 KLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTE 676
                 + +PT    ++  T  P L   +P EP+     P   KE  +  P  PT    +
Sbjct: 194 ------LAKPTP--KAETTTKGPALT--TPKEPT-----PTTPKEPASTTPKEPTPTTIK 238

Query: 677 ASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPG----KSPSKKKKKFRTPSFLKKS 731
           ++P    +PAP   ++AP+  +E A   P +   P     K P+    K   P+  K +
Sbjct: 239 SAPTTPKEPAPTTTKSAPTTPKEPA---PTTTKEPAPTTPKEPAPTTTKEPAPTTTKSA 294



 Score = 33.9 bits (76), Expect = 0.56
 Identities = 33/119 (27%), Positives = 43/119 (36%), Gaps = 15/119 (12%)

Query: 602 PDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKE 661
           P  P  P P    P   +E   P  TT D     T K T P  +P EP+          +
Sbjct: 588 PTTPKKPAPKELAPTTTKE---PTSTTCDKPAPTTPKGTAPT-TPKEPAPTT------PK 637

Query: 662 EEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKKKK 720
           E A   P  T   T   P P     P  +E AP+  +      P S  S   +P+  K+
Sbjct: 638 EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK-----GPTSTTSDKPAPTTPKE 691



 Score = 33.1 bits (74), Expect = 0.95
 Identities = 31/90 (34%), Positives = 36/90 (40%), Gaps = 9/90 (10%)

Query: 597 KEKSP--PDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFK-PTLPDLSPDEPSEAL 653
           KE +P  P +PA   P    P   E    P PTT + S   T K PT    SPDE +  L
Sbjct: 690 KETAPTTPKEPAPTTPKKPAPTTPE---TPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 746

Query: 654 GFPMLEK--EEEAHRPPSP-TEAPTEASPE 680
                 K  E     P  P T+ P    PE
Sbjct: 747 SAEPTPKALENSPKEPGVPTTKTPAATKPE 776


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 49/184 (26%), Positives = 73/184 (39%), Gaps = 17/184 (9%)

Query: 558 TTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKSPPDQ------PAVPHPP 611
           TT  N  T+   +E     +E +  +K S ++L    +   K  P        PA+  P 
Sbjct: 196 TTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPK 255

Query: 612 PSTPIKLEEDLVPEPTTGDDSDAATFK--PTLPDLSPDEPSEALGFPMLEKEEE--AHRP 667
             TP   +E   P  TT  +    T K  PT P      P+     P   KE      + 
Sbjct: 256 EPTPTTPKE---PASTTPKEPTPTTIKSAPTTP--KEPAPTTTKSAPTTPKEPAPTTTKE 310

Query: 668 PSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDG-SPGKSPSKKKKKFRTPS 726
           P+PT  P E +P    +PAP   ++AP+  +E A   P     +  K P+    K  TP+
Sbjct: 311 PAPT-TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPT 369

Query: 727 FLKK 730
             K+
Sbjct: 370 TPKE 373



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 43/148 (29%), Positives = 59/148 (39%), Gaps = 22/148 (14%)

Query: 599 KSPPDQPAVP------HPPPSTPIKLEEDLVPEPTTGDDSDAATFK---PTLPDLSPDEP 649
           KS P  P  P       P P+TP +      P PTT  +    T K   PT  + +P  P
Sbjct: 333 KSAPTTPKEPAPTTPKKPAPTTPKE------PAPTTPKEPTPTTPKEPAPTTKEPAPTTP 386

Query: 650 SEALGFPMLEKEEEAHRPPSPTE----APT---EASPEPAPDPAPVAEEAAPSAVEEGAA 702
            E       +      + P+PT     APT   E SP    +PAP   ++AP+  +E A 
Sbjct: 387 KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP 446

Query: 703 ADPGSDGSPGKSPSKKKKKFRTPSFLKK 730
               S  +  K PS    K   P+  K+
Sbjct: 447 TTTKSAPTTPKEPSPTTTKEPAPTTPKE 474



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 42/145 (28%), Positives = 56/145 (38%), Gaps = 16/145 (11%)

Query: 591 DEAREQKEKSP--PDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDE 648
           + A   KE +P  P +PA   P    P   +E   P PTT  +    T K   P  +P E
Sbjct: 373 EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE---PAPTTPKEPAPTTTKEPSPT-TPKE 428

Query: 649 PSEAL--GFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVA-EEAAPSAVEEGAAADP 705
           P+       P   KE       S    P E SP    +PAP   +E AP+  ++ A   P
Sbjct: 429 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP 488

Query: 706 GSDGSPGKSPSKKKKKFRTPSFLKK 730
                  K P+    K   P+  KK
Sbjct: 489 -------KEPAPTTPKEPAPTTTKK 506



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 36/131 (27%), Positives = 54/131 (41%), Gaps = 19/131 (14%)

Query: 597 KEKSP--PDQPA--VPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEA 652
           KE +P  P +PA     P P+TP +      P PT        T K   P  +P EP+  
Sbjct: 364 KEPTPTTPKEPAPTTKEPAPTTPKE------PAPTAPKKPAPTTPKEPAPT-TPKEPA-- 414

Query: 653 LGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGA---AADPGSDG 709
              P   KE     P  P    T+++P    +PAP   ++AP+  +E +     +P    
Sbjct: 415 ---PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT 471

Query: 710 SPGKSPSKKKK 720
               +P+  KK
Sbjct: 472 PKEPAPTTPKK 482



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 40/142 (28%), Positives = 58/142 (40%), Gaps = 22/142 (15%)

Query: 597 KEKSP--PDQPA---VPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKP--TLPDLSPDEP 649
           KE +P  P +PA      P P+TP +      P PTT   +   T +P  T    +P  P
Sbjct: 403 KEPAPTTPKEPAPTTTKEPSPTTPKE------PAPTTTKSAPTTTKEPAPTTTKSAPTTP 456

Query: 650 SEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVA-EEAAPSAVEEGAAADPGSD 708
            E       E      + P+PT  P + +P    +PAP   +E AP+  ++ A   P   
Sbjct: 457 KEPSPTTTKEPAPTTPKEPAPT-TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP--- 512

Query: 709 GSPGKSPSKKKKKFRTPSFLKK 730
               K P+    K   P+  KK
Sbjct: 513 ----KEPAPTTPKETAPTTPKK 530



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 37/131 (28%), Positives = 56/131 (42%), Gaps = 17/131 (12%)

Query: 595 EQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALG 654
           E+   + P++PA   P    P   EE   P PTT ++    T K   P+ +P EP+    
Sbjct: 537 EKLAPTTPEKPAPTTPEELAPTTPEE---PTPTTPEEPAPTTPKAAAPN-TPKEPA---- 588

Query: 655 FPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEA-APSAVEEGAAADPGSDGSPGK 713
            P   KE      P+PT  P E +P    + AP   +  AP+ ++E A   P        
Sbjct: 589 -PTTPKE------PAPT-TPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKEL 640

Query: 714 SPSKKKKKFRT 724
           +P+  K+   T
Sbjct: 641 APTTTKEPTST 651



 Score = 38.5 bits (88), Expect = 0.023
 Identities = 44/141 (31%), Positives = 62/141 (43%), Gaps = 26/141 (18%)

Query: 597 KEKSP--PDQPA---VPHPPPSTPIKLEEDLVPEPTTGDDSDAATFK---PTLPD-LSPD 647
           KE +P  P +PA      P P+TP +      P PTT  ++   T K   PT P+ L+P 
Sbjct: 489 KEPAPTTPKEPAPTTTKKPAPTTPKE------PAPTTPKETAPTTPKKLTPTTPEKLAPT 542

Query: 648 EPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVA-EEAAPSAVEEGAAADPG 706
            P +    P     EE    P+  E PT  +PE   +PAP   + AAP+  +E A   P 
Sbjct: 543 TPEK----PAPTTPEEL--APTTPEEPTPTTPE---EPAPTTPKAAAPNTPKEPAPTTPK 593

Query: 707 SDG-SPGKSPSKKKKKFRTPS 726
               +  K P+    K   P+
Sbjct: 594 EPAPTTPKEPAPTTPKETAPT 614



 Score = 36.6 bits (83), Expect = 0.086
 Identities = 36/131 (27%), Positives = 58/131 (44%), Gaps = 24/131 (18%)

Query: 603 DQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEE 662
           D+PA   P  + P   +E   P PTT          PT P+  P   SE +  P   KE 
Sbjct: 723 DKPAPTTPKETAPTTPKE---PAPTTPKKP-----APTTPETPPPTTSE-VSTPTTTKE- 772

Query: 663 EAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKKKKKF 722
               P +  ++P E++PE + +P P A E +P         +PG   +  K+P+  K + 
Sbjct: 773 ----PTTIHKSPDESTPELSAEPTPKALENSPK--------EPGVPTT--KTPAATKPEM 818

Query: 723 RTPSFLKKSKK 733
            T +  K +++
Sbjct: 819 TTTAKDKTTER 829



 Score = 35.0 bits (79), Expect = 0.25
 Identities = 37/179 (20%), Positives = 69/179 (38%), Gaps = 22/179 (12%)

Query: 557 STTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPI 616
           S T      T+      E +      ++ S +  ++    KE    ++ +     P++ +
Sbjct: 175 SDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKV 234

Query: 617 KLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTE 676
                 + +PT    ++  T  P L   +P EP+     P   KE  +  P  PT    +
Sbjct: 235 ------LAKPTP--KAETTTKGPALT--TPKEPT-----PTTPKEPASTTPKEPTPTTIK 279

Query: 677 ASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPG----KSPSKKKKKFRTPSFLKKS 731
           ++P    +PAP   ++AP+  +E A   P +   P     K P+    K   P+  K +
Sbjct: 280 SAPTTPKEPAPTTTKSAPTTPKEPA---PTTTKEPAPTTPKEPAPTTTKEPAPTTTKSA 335



 Score = 33.9 bits (76), Expect = 0.56
 Identities = 33/119 (27%), Positives = 43/119 (36%), Gaps = 15/119 (12%)

Query: 602 PDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKE 661
           P  P  P P    P   +E   P  TT D     T K T P  +P EP+          +
Sbjct: 629 PTTPKKPAPKELAPTTTKE---PTSTTCDKPAPTTPKGTAPT-TPKEPAPTT------PK 678

Query: 662 EEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKKKK 720
           E A   P  T   T   P P     P  +E AP+  +      P S  S   +P+  K+
Sbjct: 679 EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK-----GPTSTTSDKPAPTTPKE 732



 Score = 33.1 bits (74), Expect = 0.95
 Identities = 31/90 (34%), Positives = 36/90 (40%), Gaps = 9/90 (10%)

Query: 597 KEKSP--PDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFK-PTLPDLSPDEPSEAL 653
           KE +P  P +PA   P    P   E    P PTT + S   T K PT    SPDE +  L
Sbjct: 731 KETAPTTPKEPAPTTPKKPAPTTPE---TPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 787

Query: 654 GFPMLEK--EEEAHRPPSP-TEAPTEASPE 680
                 K  E     P  P T+ P    PE
Sbjct: 788 SAEPTPKALENSPKEPGVPTTKTPAATKPE 817


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 49/184 (26%), Positives = 73/184 (39%), Gaps = 17/184 (9%)

Query: 558 TTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKSPPDQ------PAVPHPP 611
           TT  N  T+   +E     +E +  +K S ++L    +   K  P        PA+  P 
Sbjct: 248 TTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPK 307

Query: 612 PSTPIKLEEDLVPEPTTGDDSDAATFK--PTLPDLSPDEPSEALGFPMLEKEEE--AHRP 667
             TP   +E   P  TT  +    T K  PT P      P+     P   KE      + 
Sbjct: 308 EPTPTTPKE---PASTTPKEPTPTTIKSAPTTP--KEPAPTTTKSAPTTPKEPAPTTTKE 362

Query: 668 PSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDG-SPGKSPSKKKKKFRTPS 726
           P+PT  P E +P    +PAP   ++AP+  +E A   P     +  K P+    K  TP+
Sbjct: 363 PAPT-TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPT 421

Query: 727 FLKK 730
             K+
Sbjct: 422 TPKE 425



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 43/148 (29%), Positives = 59/148 (39%), Gaps = 22/148 (14%)

Query: 599 KSPPDQPAVP------HPPPSTPIKLEEDLVPEPTTGDDSDAATFK---PTLPDLSPDEP 649
           KS P  P  P       P P+TP +      P PTT  +    T K   PT  + +P  P
Sbjct: 385 KSAPTTPKEPAPTTPKKPAPTTPKE------PAPTTPKEPTPTTPKEPAPTTKEPAPTTP 438

Query: 650 SEALGFPMLEKEEEAHRPPSPTE----APT---EASPEPAPDPAPVAEEAAPSAVEEGAA 702
            E       +      + P+PT     APT   E SP    +PAP   ++AP+  +E A 
Sbjct: 439 KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP 498

Query: 703 ADPGSDGSPGKSPSKKKKKFRTPSFLKK 730
               S  +  K PS    K   P+  K+
Sbjct: 499 TTTKSAPTTPKEPSPTTTKEPAPTTPKE 526



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 42/145 (28%), Positives = 56/145 (38%), Gaps = 16/145 (11%)

Query: 591 DEAREQKEKSP--PDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDE 648
           + A   KE +P  P +PA   P    P   +E   P PTT  +    T K   P  +P E
Sbjct: 425 EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE---PAPTTPKEPAPTTTKEPSPT-TPKE 480

Query: 649 PSEAL--GFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVA-EEAAPSAVEEGAAADP 705
           P+       P   KE       S    P E SP    +PAP   +E AP+  ++ A   P
Sbjct: 481 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP 540

Query: 706 GSDGSPGKSPSKKKKKFRTPSFLKK 730
                  K P+    K   P+  KK
Sbjct: 541 -------KEPAPTTPKEPAPTTTKK 558



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 36/131 (27%), Positives = 54/131 (41%), Gaps = 19/131 (14%)

Query: 597 KEKSP--PDQPA--VPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEA 652
           KE +P  P +PA     P P+TP +      P PT        T K   P  +P EP+  
Sbjct: 416 KEPTPTTPKEPAPTTKEPAPTTPKE------PAPTAPKKPAPTTPKEPAPT-TPKEPA-- 466

Query: 653 LGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGA---AADPGSDG 709
              P   KE     P  P    T+++P    +PAP   ++AP+  +E +     +P    
Sbjct: 467 ---PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT 523

Query: 710 SPGKSPSKKKK 720
               +P+  KK
Sbjct: 524 PKEPAPTTPKK 534



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 40/142 (28%), Positives = 58/142 (40%), Gaps = 22/142 (15%)

Query: 597 KEKSP--PDQPA---VPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKP--TLPDLSPDEP 649
           KE +P  P +PA      P P+TP +      P PTT   +   T +P  T    +P  P
Sbjct: 455 KEPAPTTPKEPAPTTTKEPSPTTPKE------PAPTTTKSAPTTTKEPAPTTTKSAPTTP 508

Query: 650 SEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVA-EEAAPSAVEEGAAADPGSD 708
            E       E      + P+PT  P + +P    +PAP   +E AP+  ++ A   P   
Sbjct: 509 KEPSPTTTKEPAPTTPKEPAPT-TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP--- 564

Query: 709 GSPGKSPSKKKKKFRTPSFLKK 730
               K P+    K   P+  KK
Sbjct: 565 ----KEPAPTTPKETAPTTPKK 582



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 37/131 (28%), Positives = 56/131 (42%), Gaps = 17/131 (12%)

Query: 595 EQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALG 654
           E+   + P++PA   P    P   EE   P PTT ++    T K   P+ +P EP+    
Sbjct: 589 EKLAPTTPEKPAPTTPEELAPTTPEE---PTPTTPEEPAPTTPKAAAPN-TPKEPA---- 640

Query: 655 FPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEA-APSAVEEGAAADPGSDGSPGK 713
            P   KE      P+PT  P E +P    + AP   +  AP+ ++E A   P        
Sbjct: 641 -PTTPKE------PAPT-TPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKEL 692

Query: 714 SPSKKKKKFRT 724
           +P+  K+   T
Sbjct: 693 APTTTKEPTST 703



 Score = 38.5 bits (88), Expect = 0.023
 Identities = 44/141 (31%), Positives = 62/141 (43%), Gaps = 26/141 (18%)

Query: 597 KEKSP--PDQPA---VPHPPPSTPIKLEEDLVPEPTTGDDSDAATFK---PTLPD-LSPD 647
           KE +P  P +PA      P P+TP +      P PTT  ++   T K   PT P+ L+P 
Sbjct: 541 KEPAPTTPKEPAPTTTKKPAPTTPKE------PAPTTPKETAPTTPKKLTPTTPEKLAPT 594

Query: 648 EPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVA-EEAAPSAVEEGAAADPG 706
            P +    P     EE    P+  E PT  +PE   +PAP   + AAP+  +E A   P 
Sbjct: 595 TPEK----PAPTTPEEL--APTTPEEPTPTTPE---EPAPTTPKAAAPNTPKEPAPTTPK 645

Query: 707 SDG-SPGKSPSKKKKKFRTPS 726
               +  K P+    K   P+
Sbjct: 646 EPAPTTPKEPAPTTPKETAPT 666



 Score = 36.6 bits (83), Expect = 0.086
 Identities = 36/131 (27%), Positives = 58/131 (44%), Gaps = 24/131 (18%)

Query: 603 DQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEE 662
           D+PA   P  + P   +E   P PTT          PT P+  P   SE +  P   KE 
Sbjct: 775 DKPAPTTPKETAPTTPKE---PAPTTPKKP-----APTTPETPPPTTSE-VSTPTTTKE- 824

Query: 663 EAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKKKKKF 722
               P +  ++P E++PE + +P P A E +P         +PG   +  K+P+  K + 
Sbjct: 825 ----PTTIHKSPDESTPELSAEPTPKALENSPK--------EPGVPTT--KTPAATKPEM 870

Query: 723 RTPSFLKKSKK 733
            T +  K +++
Sbjct: 871 TTTAKDKTTER 881



 Score = 35.0 bits (79), Expect = 0.25
 Identities = 37/179 (20%), Positives = 69/179 (38%), Gaps = 22/179 (12%)

Query: 557 STTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPI 616
           S T      T+      E +      ++ S +  ++    KE    ++ +     P++ +
Sbjct: 227 SDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKV 286

Query: 617 KLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTE 676
                 + +PT    ++  T  P L   +P EP+     P   KE  +  P  PT    +
Sbjct: 287 ------LAKPTP--KAETTTKGPALT--TPKEPT-----PTTPKEPASTTPKEPTPTTIK 331

Query: 677 ASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPG----KSPSKKKKKFRTPSFLKKS 731
           ++P    +PAP   ++AP+  +E A   P +   P     K P+    K   P+  K +
Sbjct: 332 SAPTTPKEPAPTTTKSAPTTPKEPA---PTTTKEPAPTTPKEPAPTTTKEPAPTTTKSA 387



 Score = 33.9 bits (76), Expect = 0.56
 Identities = 33/119 (27%), Positives = 43/119 (36%), Gaps = 15/119 (12%)

Query: 602 PDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKE 661
           P  P  P P    P   +E   P  TT D     T K T P  +P EP+          +
Sbjct: 681 PTTPKKPAPKELAPTTTKE---PTSTTCDKPAPTTPKGTAPT-TPKEPAPTT------PK 730

Query: 662 EEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKKKK 720
           E A   P  T   T   P P     P  +E AP+  +      P S  S   +P+  K+
Sbjct: 731 EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK-----GPTSTTSDKPAPTTPKE 784



 Score = 33.1 bits (74), Expect = 0.95
 Identities = 31/90 (34%), Positives = 36/90 (40%), Gaps = 9/90 (10%)

Query: 597 KEKSP--PDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFK-PTLPDLSPDEPSEAL 653
           KE +P  P +PA   P    P   E    P PTT + S   T K PT    SPDE +  L
Sbjct: 783 KETAPTTPKEPAPTTPKKPAPTTPE---TPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 839

Query: 654 GFPMLEK--EEEAHRPPSP-TEAPTEASPE 680
                 K  E     P  P T+ P    PE
Sbjct: 840 SAEPTPKALENSPKEPGVPTTKTPAATKPE 869


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 49/184 (26%), Positives = 73/184 (39%), Gaps = 17/184 (9%)

Query: 558 TTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKSPPDQ------PAVPHPP 611
           TT  N  T+   +E     +E +  +K S ++L    +   K  P        PA+  P 
Sbjct: 289 TTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPK 348

Query: 612 PSTPIKLEEDLVPEPTTGDDSDAATFK--PTLPDLSPDEPSEALGFPMLEKEEE--AHRP 667
             TP   +E   P  TT  +    T K  PT P      P+     P   KE      + 
Sbjct: 349 EPTPTTPKE---PASTTPKEPTPTTIKSAPTTP--KEPAPTTTKSAPTTPKEPAPTTTKE 403

Query: 668 PSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDG-SPGKSPSKKKKKFRTPS 726
           P+PT  P E +P    +PAP   ++AP+  +E A   P     +  K P+    K  TP+
Sbjct: 404 PAPT-TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPT 462

Query: 727 FLKK 730
             K+
Sbjct: 463 TPKE 466



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 43/148 (29%), Positives = 59/148 (39%), Gaps = 22/148 (14%)

Query: 599 KSPPDQPAVP------HPPPSTPIKLEEDLVPEPTTGDDSDAATFK---PTLPDLSPDEP 649
           KS P  P  P       P P+TP +      P PTT  +    T K   PT  + +P  P
Sbjct: 426 KSAPTTPKEPAPTTPKKPAPTTPKE------PAPTTPKEPTPTTPKEPAPTTKEPAPTTP 479

Query: 650 SEALGFPMLEKEEEAHRPPSPTE----APT---EASPEPAPDPAPVAEEAAPSAVEEGAA 702
            E       +      + P+PT     APT   E SP    +PAP   ++AP+  +E A 
Sbjct: 480 KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP 539

Query: 703 ADPGSDGSPGKSPSKKKKKFRTPSFLKK 730
               S  +  K PS    K   P+  K+
Sbjct: 540 TTTKSAPTTPKEPSPTTTKEPAPTTPKE 567



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 42/145 (28%), Positives = 56/145 (38%), Gaps = 16/145 (11%)

Query: 591 DEAREQKEKSP--PDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDE 648
           + A   KE +P  P +PA   P    P   +E   P PTT  +    T K   P  +P E
Sbjct: 466 EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE---PAPTTPKEPAPTTTKEPSPT-TPKE 521

Query: 649 PSEAL--GFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVA-EEAAPSAVEEGAAADP 705
           P+       P   KE       S    P E SP    +PAP   +E AP+  ++ A   P
Sbjct: 522 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP 581

Query: 706 GSDGSPGKSPSKKKKKFRTPSFLKK 730
                  K P+    K   P+  KK
Sbjct: 582 -------KEPAPTTPKEPAPTTTKK 599



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 36/131 (27%), Positives = 54/131 (41%), Gaps = 19/131 (14%)

Query: 597 KEKSP--PDQPA--VPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEA 652
           KE +P  P +PA     P P+TP +      P PT        T K   P  +P EP+  
Sbjct: 457 KEPTPTTPKEPAPTTKEPAPTTPKE------PAPTAPKKPAPTTPKEPAPT-TPKEPA-- 507

Query: 653 LGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGA---AADPGSDG 709
              P   KE     P  P    T+++P    +PAP   ++AP+  +E +     +P    
Sbjct: 508 ---PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT 564

Query: 710 SPGKSPSKKKK 720
               +P+  KK
Sbjct: 565 PKEPAPTTPKK 575



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 40/142 (28%), Positives = 58/142 (40%), Gaps = 22/142 (15%)

Query: 597 KEKSP--PDQPA---VPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKP--TLPDLSPDEP 649
           KE +P  P +PA      P P+TP +      P PTT   +   T +P  T    +P  P
Sbjct: 496 KEPAPTTPKEPAPTTTKEPSPTTPKE------PAPTTTKSAPTTTKEPAPTTTKSAPTTP 549

Query: 650 SEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVA-EEAAPSAVEEGAAADPGSD 708
            E       E      + P+PT  P + +P    +PAP   +E AP+  ++ A   P   
Sbjct: 550 KEPSPTTTKEPAPTTPKEPAPT-TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP--- 605

Query: 709 GSPGKSPSKKKKKFRTPSFLKK 730
               K P+    K   P+  KK
Sbjct: 606 ----KEPAPTTPKETAPTTPKK 623



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 37/131 (28%), Positives = 56/131 (42%), Gaps = 17/131 (12%)

Query: 595 EQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALG 654
           E+   + P++PA   P    P   EE   P PTT ++    T K   P+ +P EP+    
Sbjct: 630 EKLAPTTPEKPAPTTPEELAPTTPEE---PTPTTPEEPAPTTPKAAAPN-TPKEPA---- 681

Query: 655 FPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEA-APSAVEEGAAADPGSDGSPGK 713
            P   KE      P+PT  P E +P    + AP   +  AP+ ++E A   P        
Sbjct: 682 -PTTPKE------PAPT-TPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKEL 733

Query: 714 SPSKKKKKFRT 724
           +P+  K+   T
Sbjct: 734 APTTTKEPTST 744



 Score = 38.5 bits (88), Expect = 0.023
 Identities = 44/141 (31%), Positives = 62/141 (43%), Gaps = 26/141 (18%)

Query: 597 KEKSP--PDQPA---VPHPPPSTPIKLEEDLVPEPTTGDDSDAATFK---PTLPD-LSPD 647
           KE +P  P +PA      P P+TP +      P PTT  ++   T K   PT P+ L+P 
Sbjct: 582 KEPAPTTPKEPAPTTTKKPAPTTPKE------PAPTTPKETAPTTPKKLTPTTPEKLAPT 635

Query: 648 EPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVA-EEAAPSAVEEGAAADPG 706
            P +    P     EE    P+  E PT  +PE   +PAP   + AAP+  +E A   P 
Sbjct: 636 TPEK----PAPTTPEEL--APTTPEEPTPTTPE---EPAPTTPKAAAPNTPKEPAPTTPK 686

Query: 707 SDG-SPGKSPSKKKKKFRTPS 726
               +  K P+    K   P+
Sbjct: 687 EPAPTTPKEPAPTTPKETAPT 707



 Score = 36.6 bits (83), Expect = 0.086
 Identities = 36/131 (27%), Positives = 58/131 (44%), Gaps = 24/131 (18%)

Query: 603 DQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEE 662
           D+PA   P  + P   +E   P PTT          PT P+  P   SE +  P   KE 
Sbjct: 816 DKPAPTTPKETAPTTPKE---PAPTTPKKP-----APTTPETPPPTTSE-VSTPTTTKE- 865

Query: 663 EAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKKKKKF 722
               P +  ++P E++PE + +P P A E +P         +PG   +  K+P+  K + 
Sbjct: 866 ----PTTIHKSPDESTPELSAEPTPKALENSPK--------EPGVPTT--KTPAATKPEM 911

Query: 723 RTPSFLKKSKK 733
            T +  K +++
Sbjct: 912 TTTAKDKTTER 922



 Score = 35.0 bits (79), Expect = 0.25
 Identities = 37/179 (20%), Positives = 69/179 (38%), Gaps = 22/179 (12%)

Query: 557 STTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPI 616
           S T      T+      E +      ++ S +  ++    KE    ++ +     P++ +
Sbjct: 268 SDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKV 327

Query: 617 KLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTE 676
                 + +PT    ++  T  P L   +P EP+     P   KE  +  P  PT    +
Sbjct: 328 ------LAKPTP--KAETTTKGPALT--TPKEPT-----PTTPKEPASTTPKEPTPTTIK 372

Query: 677 ASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPG----KSPSKKKKKFRTPSFLKKS 731
           ++P    +PAP   ++AP+  +E A   P +   P     K P+    K   P+  K +
Sbjct: 373 SAPTTPKEPAPTTTKSAPTTPKEPA---PTTTKEPAPTTPKEPAPTTTKEPAPTTTKSA 428



 Score = 33.9 bits (76), Expect = 0.56
 Identities = 33/119 (27%), Positives = 43/119 (36%), Gaps = 15/119 (12%)

Query: 602 PDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKE 661
           P  P  P P    P   +E   P  TT D     T K T P  +P EP+          +
Sbjct: 722 PTTPKKPAPKELAPTTTKE---PTSTTCDKPAPTTPKGTAPT-TPKEPAPTT------PK 771

Query: 662 EEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKKKK 720
           E A   P  T   T   P P     P  +E AP+  +      P S  S   +P+  K+
Sbjct: 772 EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK-----GPTSTTSDKPAPTTPKE 825



 Score = 33.1 bits (74), Expect = 0.95
 Identities = 31/90 (34%), Positives = 36/90 (40%), Gaps = 9/90 (10%)

Query: 597 KEKSP--PDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFK-PTLPDLSPDEPSEAL 653
           KE +P  P +PA   P    P   E    P PTT + S   T K PT    SPDE +  L
Sbjct: 824 KETAPTTPKEPAPTTPKKPAPTTPE---TPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 880

Query: 654 GFPMLEK--EEEAHRPPSP-TEAPTEASPE 680
                 K  E     P  P T+ P    PE
Sbjct: 881 SAEPTPKALENSPKEPGVPTTKTPAATKPE 910


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 42/145 (28%), Positives = 48/145 (33%), Gaps = 33/145 (22%)

Query: 598  EKSPPDQPAVPHPPPSTPIKLEEDL-----------VPEPTTGDDSDAATFKPTLPDLSP 646
            +  PP  PAVPHPPPS    L   L            P P    D +      TLP  S 
Sbjct: 1323 QPQPPATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKRLDEELKRNLETLPSFSS 1382

Query: 647  DEPS----------------EALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVAE 690
            DE                   AL  P L   ++   P  P  AP  A P P P P     
Sbjct: 1383 DEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLP----- 1437

Query: 691  EAAPSAVEEGAAADPGSDGSPGKSP 715
               PSA   G    P  +  P  +P
Sbjct: 1438 -GLPSANSNGTPEPPLLEEKPPPTP 1461



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 45/142 (31%), Positives = 52/142 (36%), Gaps = 15/142 (10%)

Query: 597  KEKSPPDQP------AVPHPPPSTPI-KLEEDLVPEPTTGDDSDAATFKPT-----LPDL 644
            K+ S PD P      AVP PPP   +     +  PEP   ++    T  P       P  
Sbjct: 1414 KDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPP 1473

Query: 645  SPDEPSEALGFPM-LEKEEEAHRPPSP-TEAPTEASPEPAPDPAPVAEEAAPSAVEEGAA 702
             P  P  AL  P  L     +  PP P    P  A P P P P P A   A +  EE AA
Sbjct: 1474 PPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLA-APPEEPAA 1532

Query: 703  ADPGSDGSPGKSPSKKKKKFRT 724
              P     P   P    KK  T
Sbjct: 1533 PSPEDPELPDTRPLHLAKKQET 1554



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 38/159 (23%), Positives = 59/159 (37%), Gaps = 8/159 (5%)

Query: 561  PNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEE 620
            P+P   L D EL+     +       E+++ + R+ +E       A+  PP + P   ++
Sbjct: 1360 PSPCKRL-DEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGP---KD 1415

Query: 621  DLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPE 680
               P+      + A    P LP L     +     P+LE++     PP+PT  P    P 
Sbjct: 1416 TSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPP 1475

Query: 681  PAPDPA----PVAEEAAPSAVEEGAAADPGSDGSPGKSP 715
            P P PA    P      PS+        P     P   P
Sbjct: 1476 PPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPP 1514



 Score = 33.5 bits (75), Expect = 0.73
 Identities = 32/135 (23%), Positives = 50/135 (37%), Gaps = 15/135 (11%)

Query: 594  REQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPD-LSPDEPSEA 652
            R  + K+P        PPP  P    +   PE TT +     T +  +P+  +P++PS  
Sbjct: 1676 RSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPSLL 1735

Query: 653  LGFPMLEKEEEAHRPPSPTEAPTEAS-----PEPAPDPAPVAEEAAPSAVEEGAAADPGS 707
                  +++E+  R   P       S     PE +      A    P A      A+P  
Sbjct: 1736 RPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARPTKVKAEP-- 1793

Query: 708  DGSPGKSPSKKKKKF 722
                   P KK+KK+
Sbjct: 1794 -------PPKKRKKW 1801



 Score = 33.1 bits (74), Expect = 0.95
 Identities = 33/120 (27%), Positives = 41/120 (34%), Gaps = 33/120 (27%)

Query: 601  PPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEK 660
            PP QPA+P PPP         + P P++          P  P L P  P      P    
Sbjct: 1476 PPPQPALPSPPPL--------VAPTPSS----------PPPPPLPPPPPPAMPSPPP--- 1514

Query: 661  EEEAHRPPSPTEAPTEASPE------PAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKS 714
                  PP P  AP  A PE      P     P       +  +E AA    +D   G+S
Sbjct: 1515 ------PPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAVCGETDEEAGES 1568



 Score = 31.6 bits (70), Expect = 2.8
 Identities = 45/181 (24%), Positives = 64/181 (35%), Gaps = 31/181 (17%)

Query: 552  PHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPP 611
            P  +  T+   P + L D E   +    E    G+ ++  +A   +++  P   A P P 
Sbjct: 924  PRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPG 983

Query: 612  PSTPIKLEEDLVPEPTTGDDSDAATFKPTL---PDLSPDEPSEALGFPMLEKEEEAHR-- 666
            P        D       G  S A    P L   P+  P+ PS     P+   +   H+  
Sbjct: 984  PPA-----YDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAA 1038

Query: 667  PPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKKKKKFRTPS 726
            PP P        P P P PAP +E               G   SP    +K KK  +T S
Sbjct: 1039 PPPP--------PPPPPPPAPASE-------------PKGGLTSPIFCSTKPKKLLKTSS 1077

Query: 727  F 727
            F
Sbjct: 1078 F 1078



 Score = 30.4 bits (67), Expect = 6.2
 Identities = 37/140 (26%), Positives = 52/140 (37%), Gaps = 25/140 (17%)

Query: 597 KEKSPPDQPAVPHPPPSTPIKLEED--------------LVPEPTTGDDSDAATFKPTLP 642
           ++ +P   P  P PPP  P++LE                L PE +             L 
Sbjct: 829 RDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALE 888

Query: 643 DLSPDEPSEALGFPMLEKEEE--AHRPPSP--TEAPTEASPEPAPDPAPVAEEAAPS--- 695
            L P      +G P  E ++   A+R PSP  T+AP          P  + ++   S   
Sbjct: 889 PLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFP 948

Query: 696 AVEE----GAAADPGSDGSP 711
            +EE    GAA D G  G P
Sbjct: 949 TMEEMFGGGAADDYGKAGPP 968


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.130    0.374 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,738,728
Number of Sequences: 37866
Number of extensions: 1893294
Number of successful extensions: 19235
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 204
Number of HSP's successfully gapped in prelim test: 1046
Number of HSP's that attempted gapping in prelim test: 12411
Number of HSP's gapped (non-prelim): 5589
length of query: 737
length of database: 18,247,518
effective HSP length: 110
effective length of query: 627
effective length of database: 14,082,258
effective search space: 8829575766
effective search space used: 8829575766
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.